LOCUS       DAFLWC010000001       100707 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.001, whole genome shotgun sequence.
ACCESSION   DAFLWC010000001 DAFLWC010000000
VERSION     DAFLWC010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 100707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 100707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..100707
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.001"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(553..2166)
                     /locus_tag="L1V17_000001"
     CDS             complement(553..2166)
                     /locus_tag="L1V17_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBN1234801.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2307..3215)
                     /locus_tag="L1V17_000002"
     CDS             complement(2307..3215)
                     /locus_tag="L1V17_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1234802.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            3398..4522
                     /locus_tag="L1V17_000003"
     CDS             3398..4522
                     /locus_tag="L1V17_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBN1234803.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            4749..5666
                     /locus_tag="L1V17_000004"
     CDS             4749..5666
                     /locus_tag="L1V17_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1234804.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            5659..6492
                     /locus_tag="L1V17_000005"
     CDS             5659..6492
                     /locus_tag="L1V17_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1234805.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            6575..7693
                     /locus_tag="L1V17_000006"
     CDS             6575..7693
                     /locus_tag="L1V17_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBN1234806.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            7687..9585
                     /locus_tag="L1V17_000007"
     CDS             7687..9585
                     /locus_tag="L1V17_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HBN1234807.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            9579..10802
                     /locus_tag="L1V17_000008"
     CDS             9579..10802
                     /locus_tag="L1V17_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBN1234808.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(10888..12822)
                     /locus_tag="L1V17_000009"
     CDS             complement(10888..12822)
                     /locus_tag="L1V17_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBN1234809.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            13048..13704
                     /locus_tag="L1V17_000010"
     CDS             13048..13704
                     /locus_tag="L1V17_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBN1234810.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            complement(13778..14131)
                     /locus_tag="L1V17_000011"
     CDS             complement(13778..14131)
                     /locus_tag="L1V17_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBN1234811.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            14323..15252
                     /locus_tag="L1V17_000012"
     CDS             14323..15252
                     /locus_tag="L1V17_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBN1234812.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            15263..16099
                     /locus_tag="L1V17_000013"
     CDS             15263..16099
                     /locus_tag="L1V17_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HBN1234813.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            16347..17123
                     /locus_tag="L1V17_000014"
     CDS             16347..17123
                     /locus_tag="L1V17_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1234814.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            17299..18042
                     /locus_tag="L1V17_000015"
     CDS             17299..18042
                     /locus_tag="L1V17_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1234815.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            18035..19615
                     /locus_tag="L1V17_000016"
     CDS             18035..19615
                     /locus_tag="L1V17_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HBN1234816.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(19866..20345)
                     /locus_tag="L1V17_000017"
     CDS             complement(19866..20345)
                     /locus_tag="L1V17_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBN1234817.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(20361..21113)
                     /locus_tag="L1V17_000018"
     CDS             complement(20361..21113)
                     /locus_tag="L1V17_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBN1234818.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            21230..21300
                     /locus_tag="L1V17_000019"
     tRNA            21230..21300
                     /locus_tag="L1V17_000019"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21262..21264,aa:Gly,seq:ccc)
     gene            21661..22386
                     /locus_tag="L1V17_000020"
     CDS             21661..22386
                     /locus_tag="L1V17_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HBN1234819.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            22641..22907
                     /locus_tag="L1V17_000021"
     CDS             22641..22907
                     /locus_tag="L1V17_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBN1234820.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPSYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            22904..23335
                     /gene="ruvX"
                     /locus_tag="L1V17_000022"
     CDS             22904..23335
                     /gene="ruvX"
                     /locus_tag="L1V17_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBN1234821.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            23360..23665
                     /locus_tag="L1V17_000023"
     CDS             23360..23665
                     /locus_tag="L1V17_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBN1234822.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(23746..24891)
                     /locus_tag="L1V17_000024"
     CDS             complement(23746..24891)
                     /locus_tag="L1V17_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1234823.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(24952..25599)
                     /locus_tag="L1V17_000025"
     CDS             complement(24952..25599)
                     /locus_tag="L1V17_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1234824.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            25793..26086
                     /locus_tag="L1V17_000026"
     CDS             25793..26086
                     /locus_tag="L1V17_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1234825.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            26130..26441
                     /locus_tag="L1V17_000027"
     CDS             26130..26441
                     /locus_tag="L1V17_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1234826.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            26438..27062
                     /locus_tag="L1V17_000028"
                     /pseudo
     CDS             26438..27062
                     /locus_tag="L1V17_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            27203..27361
                     /locus_tag="L1V17_000029"
     CDS             27203..27361
                     /locus_tag="L1V17_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1234827.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            27362..27724
                     /locus_tag="L1V17_000030"
     CDS             27362..27724
                     /locus_tag="L1V17_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1234828.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            27761..28609
                     /locus_tag="L1V17_000031"
     CDS             27761..28609
                     /locus_tag="L1V17_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HBN1234829.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            28599..30074
                     /locus_tag="L1V17_000032"
     CDS             28599..30074
                     /locus_tag="L1V17_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HBN1234830.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            30340..30747
                     /locus_tag="L1V17_000033"
     CDS             30340..30747
                     /locus_tag="L1V17_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HBN1234831.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            30750..30965
                     /locus_tag="L1V17_000034"
     CDS             30750..30965
                     /locus_tag="L1V17_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1234832.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            30969..31349
                     /locus_tag="L1V17_000035"
     CDS             30969..31349
                     /locus_tag="L1V17_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBN1234833.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            31483..31638
                     /locus_tag="L1V17_000036"
     CDS             31483..31638
                     /locus_tag="L1V17_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HBN1234834.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            31707..32180
                     /locus_tag="L1V17_000037"
     CDS             31707..32180
                     /locus_tag="L1V17_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HBN1234835.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            32177..33871
                     /locus_tag="L1V17_000038"
     CDS             32177..33871
                     /locus_tag="L1V17_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBN1234836.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            33837..34022
                     /locus_tag="L1V17_000039"
     CDS             33837..34022
                     /locus_tag="L1V17_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1234837.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            34026..35201
                     /locus_tag="L1V17_000040"
     CDS             34026..35201
                     /locus_tag="L1V17_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBN1234838.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            35194..36717
                     /locus_tag="L1V17_000041"
     CDS             35194..36717
                     /locus_tag="L1V17_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBN1234839.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            36773..37057
                     /locus_tag="L1V17_000042"
     CDS             36773..37057
                     /locus_tag="L1V17_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBN1234840.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            37044..37379
                     /locus_tag="L1V17_000043"
     CDS             37044..37379
                     /locus_tag="L1V17_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBN1234841.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            37674..38300
                     /locus_tag="L1V17_000044"
     CDS             37674..38300
                     /locus_tag="L1V17_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1234842.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            39042..39878
                     /locus_tag="L1V17_000045"
     CDS             39042..39878
                     /locus_tag="L1V17_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBN1234843.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLINLYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            39942..40373
                     /locus_tag="L1V17_000046"
     CDS             39942..40373
                     /locus_tag="L1V17_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1234844.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(40435..41757)
                     /locus_tag="L1V17_000047"
     CDS             complement(40435..41757)
                     /locus_tag="L1V17_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HBN1234845.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(41911..43551)
                     /locus_tag="L1V17_000048"
     CDS             complement(41911..43551)
                     /locus_tag="L1V17_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HBN1234846.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            43884..44354
                     /locus_tag="L1V17_000049"
     CDS             43884..44354
                     /locus_tag="L1V17_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HBN1234847.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            44576..45679
                     /locus_tag="L1V17_000050"
     CDS             44576..45679
                     /locus_tag="L1V17_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBN1234848.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLKDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            45963..46643
                     /locus_tag="L1V17_000051"
     CDS             45963..46643
                     /locus_tag="L1V17_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBN1234849.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            46733..47767
                     /locus_tag="L1V17_000052"
     CDS             46733..47767
                     /locus_tag="L1V17_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBN1234850.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            47781..48116
                     /locus_tag="L1V17_000053"
     CDS             47781..48116
                     /locus_tag="L1V17_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1234851.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            48100..50580
                     /locus_tag="L1V17_000054"
     CDS             48100..50580
                     /locus_tag="L1V17_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1234852.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWKLTAGPTS"
     gene            50636..52195
                     /locus_tag="L1V17_000055"
     CDS             50636..52195
                     /locus_tag="L1V17_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1234853.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            52192..53556
                     /locus_tag="L1V17_000056"
     CDS             52192..53556
                     /locus_tag="L1V17_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBN1234854.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            53727..54797
                     /locus_tag="L1V17_000057"
     CDS             53727..54797
                     /locus_tag="L1V17_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1234855.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            54812..55480
                     /locus_tag="L1V17_000058"
     CDS             54812..55480
                     /locus_tag="L1V17_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1234856.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            55500..56078
                     /locus_tag="L1V17_000059"
     CDS             55500..56078
                     /locus_tag="L1V17_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1234857.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            56479..57390
                     /locus_tag="L1V17_000060"
     CDS             56479..57390
                     /locus_tag="L1V17_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBN1234858.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(57478..58395)
                     /locus_tag="L1V17_000061"
     CDS             complement(57478..58395)
                     /locus_tag="L1V17_000061"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HBN1234859.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            58597..59034
                     /gene="zapA"
                     /locus_tag="L1V17_000062"
     CDS             58597..59034
                     /gene="zapA"
                     /locus_tag="L1V17_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBN1234860.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            59093..59641
                     /locus_tag="L1V17_000063"
     CDS             59093..59641
                     /locus_tag="L1V17_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HBN1234861.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            59756..62116
                     /locus_tag="L1V17_000064"
     CDS             59756..62116
                     /locus_tag="L1V17_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBN1234862.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEEQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLYDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            62203..62517
                     /gene="trxA"
                     /locus_tag="L1V17_000065"
     CDS             62203..62517
                     /gene="trxA"
                     /locus_tag="L1V17_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBN1234863.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            62699..64477
                     /gene="uvrC"
                     /locus_tag="L1V17_000066"
     CDS             62699..64477
                     /gene="uvrC"
                     /locus_tag="L1V17_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBN1234864.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            64622..65521
                     /locus_tag="L1V17_000067"
     CDS             64622..65521
                     /locus_tag="L1V17_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1234865.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            65514..66776
                     /locus_tag="L1V17_000068"
     CDS             65514..66776
                     /locus_tag="L1V17_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1234866.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            66937..68835
                     /locus_tag="L1V17_000069"
     CDS             66937..68835
                     /locus_tag="L1V17_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HBN1234867.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(69165..69884)
                     /locus_tag="L1V17_000070"
     CDS             complement(69165..69884)
                     /locus_tag="L1V17_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBN1234868.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     gene            70221..70553
                     /locus_tag="L1V17_000071"
     CDS             70221..70553
                     /locus_tag="L1V17_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1234869.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            70540..72543
                     /locus_tag="L1V17_000072"
     CDS             70540..72543
                     /locus_tag="L1V17_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBN1234870.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            72562..73032
                     /locus_tag="L1V17_000073"
     CDS             72562..73032
                     /locus_tag="L1V17_000073"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBN1234871.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            73053..73637
                     /locus_tag="L1V17_000074"
     CDS             73053..73637
                     /locus_tag="L1V17_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HBN1234872.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            73652..74638
                     /locus_tag="L1V17_000075"
     CDS             73652..74638
                     /locus_tag="L1V17_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HBN1234873.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            74628..74939
                     /locus_tag="L1V17_000076"
     CDS             74628..74939
                     /locus_tag="L1V17_000076"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBN1234874.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            74961..76742
                     /locus_tag="L1V17_000077"
     CDS             74961..76742
                     /locus_tag="L1V17_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBN1234875.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            76735..78111
                     /locus_tag="L1V17_000078"
     CDS             76735..78111
                     /locus_tag="L1V17_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBN1234876.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            78118..78753
                     /locus_tag="L1V17_000079"
     CDS             78118..78753
                     /locus_tag="L1V17_000079"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBN1234877.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            78783..80138
                     /locus_tag="L1V17_000080"
     CDS             78783..80138
                     /locus_tag="L1V17_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HBN1234878.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(80330..81724)
                     /locus_tag="L1V17_000081"
     CDS             complement(80330..81724)
                     /locus_tag="L1V17_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBN1234879.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRTQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            81816..82787
                     /locus_tag="L1V17_000082"
     CDS             81816..82787
                     /locus_tag="L1V17_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBN1234880.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            82784..83566
                     /locus_tag="L1V17_000083"
     CDS             82784..83566
                     /locus_tag="L1V17_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBN1234881.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(83735..84106)
                     /locus_tag="L1V17_000084"
     CDS             complement(83735..84106)
                     /locus_tag="L1V17_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBN1234882.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            84240..84683
                     /locus_tag="L1V17_000085"
     CDS             84240..84683
                     /locus_tag="L1V17_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBN1234883.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(84726..85535)
                     /gene="yidA"
                     /locus_tag="L1V17_000086"
     CDS             complement(84726..85535)
                     /gene="yidA"
                     /locus_tag="L1V17_000086"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBN1234884.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(85554..86921)
                     /locus_tag="L1V17_000087"
     CDS             complement(85554..86921)
                     /locus_tag="L1V17_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBN1234885.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(86905..87735)
                     /locus_tag="L1V17_000088"
     CDS             complement(86905..87735)
                     /locus_tag="L1V17_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBN1234886.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            87898..88335
                     /locus_tag="L1V17_000089"
     CDS             87898..88335
                     /locus_tag="L1V17_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBN1234887.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            88411..89031
                     /locus_tag="L1V17_000090"
     CDS             88411..89031
                     /locus_tag="L1V17_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HBN1234888.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            89220..89726
                     /locus_tag="L1V17_000091"
     CDS             89220..89726
                     /locus_tag="L1V17_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HBN1234889.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            89743..90642
                     /locus_tag="L1V17_000092"
     CDS             89743..90642
                     /locus_tag="L1V17_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBN1234890.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            90729..91613
                     /locus_tag="L1V17_000093"
     CDS             90729..91613
                     /locus_tag="L1V17_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBN1234891.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(91805..91876)
                     /locus_tag="L1V17_000094"
     tRNA            complement(91805..91876)
                     /locus_tag="L1V17_000094"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(91841..91843),aa:Arg,seq:ccg)
     gene            91936..93270
                     /gene="rpoN"
                     /locus_tag="L1V17_000095"
     CDS             91936..93270
                     /gene="rpoN"
                     /locus_tag="L1V17_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBN1234892.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            93419..94510
                     /locus_tag="L1V17_000096"
     CDS             93419..94510
                     /locus_tag="L1V17_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HBN1234893.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            94551..95552
                     /gene="gap"
                     /locus_tag="L1V17_000097"
     CDS             94551..95552
                     /gene="gap"
                     /locus_tag="L1V17_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBN1234894.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            95662..96852
                     /locus_tag="L1V17_000098"
     CDS             95662..96852
                     /locus_tag="L1V17_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBN1234895.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            96956..97711
                     /locus_tag="L1V17_000099"
     CDS             96956..97711
                     /locus_tag="L1V17_000099"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBN1234896.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            97827..99125
                     /gene="eno"
                     /locus_tag="L1V17_000100"
     CDS             97827..99125
                     /gene="eno"
                     /locus_tag="L1V17_000100"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBN1234897.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            99524..100663
                     /locus_tag="L1V17_000101"
     CDS             99524..100663
                     /locus_tag="L1V17_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HBN1234898.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT        33406 a        17205 c        20781 g        29315 t
ORIGIN      
        1 gttaaataaa taggaacaaa aaaattaaat tatttaatac acacattagg gatcattcat
       61 tgaaggatta gaagacaacg aggatggcga aaaatatgat tacaatagaa aagtcgttct
      121 aaaccaatca gttcctagta tcacacaacg caagccagtc gatttggtga gattagagga
      181 gtgaaagcaa actttattat ataagaaaaa atattcgaaa gggatgctag tttaggtact
      241 agtgctgata gattaatatg atgcctcgta atattaggcg tagttactct agagacatca
      301 ctatggacta tgatttgtct cagagtcaca acatgttttt ttatgaaaag aaacagctaa
      361 aataattaaa ttgcgcaatg tttaaacttt cttaaactat aacctaataa atgtgaagaa
      421 ataatgcaca atttcttcac atttatcttc tattctatat acataccaac caacaaccct
      481 atatactttt tcatttttac tcctcaagta aaaataactc ctagaccgcg gctacccacc
      541 gcggtcgttt ttttattctt caatcaaaat cgctttgata cccaaacctg ccaagattcg
      601 ggcagaagta taagtattca atcctcttct gaaagtaatg taaacttttt tatcttttgg
      661 gatttcattg attcgatctc gtaactcatt cattggaata ttttttgttg ccgagatact
      721 gccagaaggt gctttattag gttcacgtat atctaaaaag aacgcttctt tcaaatcgtt
      781 ttcgggtata tcacttgctt tgatcgtttc tacgatattc gtcatttgat tgattgcgac
      841 ataaccagct atattcaacg ggtcacgggt agtagaatac ggtggagagt aaggcaactc
      901 caaatcaggc aaatcaaaga ctgtcaagtt tccggtgatt gctacagaaa gttctcccat
      961 ccgtttatcg acaccttttt ctccaaatgc ttgtccacct aaaatacgac cgctatctgc
     1021 atcaaaaatc agctttagat ttaatcttgt agcttctgga tagaaatagg catggtcaaa
     1081 gggagtgata aaaacagttt tataatttgt tatgcctgat gcttttaatt catgttctgt
     1141 cattcccgca taacttgctg tatgatcaaa gatttttgcg acacctgcac caatatatcc
     1201 gcgatagcgc ataggcgtac catttaaaat atctgccagc atatgtcctt gacgattggc
     1261 cgcactggaa agcatacttt ggatcggctg accagtcact acactagtcg tttcgataat
     1321 atcgccaatc gcatagatgt ccggcagatt ggtttgtaac tggtcatcaa caatgatctg
     1381 acctgtatct gataattgta tgccggttgc tttcaccact tcattcttcg gagaaacacc
     1441 aacagcaaaa attagcatat cagcagaaag gacggagcca tctgataata ctatttctcg
     1501 acctttatca cggatctcag taactcttgt ttctaaatga acggctaatc cttctttcag
     1561 caatttgtca taaactaaat tagcaatttc tggatcataa gggaaagcga cttgtggcaa
     1621 ttgatcgatt aaagtcacgt ctaagccgcg atgcttgaaa ttctcagcta attccagacc
     1681 cataacacct gcaccaagaa tgacgacatg ttgtggattt ttttcttcaa ggaacgattt
     1741 gattcgatcc gcatccgtca cactacggag gacaaagccg ttttctgctt caaaaactcc
     1801 gggaatatcc ggataatctg gtctagcacc agaagagatg atcaacttat cgtaatctgt
     1861 ttttatttct tcatttgtgg ataggtcttt aactgttaat cgcttagtag aaggatcgat
     1921 tgctgttact tcgtgtttag taaagacatc gatgttgttt tttgttttca atatttctgg
     1981 tgtacgttcg atcagcgagt cacggtcagt gatcacacct cctaaataat aaggcaaagc
     2041 acaacttgca taagaaatat tttctccgcg ttcatagata atgatttcgt gcgcttcatt
     2101 caatcgacgg aaacgagtgg caaatgaagg accgccagct acaccgccaa tgacaacaac
     2161 tttcataaaa acatctcctt ttctacgttg atcgtactat gttatggtaa aaaacagcaa
     2221 ataattgtgc cggaaaatta ttgtttattt tgaatagaca gaaaatatag agaaataatt
     2281 tgtggataaa acctaaaaat ttttttctat tttaaggata gataatactt tgaaggggat
     2341 aaccctgtat attttttaaa agctgaagaa aaatgatgga tcgaatgaaa tcctaatata
     2401 tctgcaattt ctgtataggt taattcattt tctagcacga gacgttttgc tttttccatt
     2461 tttagttctt taaaatagct aataacactt tttccattca cttttctaaa atgttttttt
     2521 aagctggctg gactgataaa aaaaatttgg gctaattgtt caagcaaaaa attttctgaa
     2581 agatgttctt ctaaatatcg tatgattgga tcaactaatt catctgaata aagaatatgc
     2641 ttttttttag gaatgacttt ctcatttgaa ggtattgtca ataaagcaag ttcctgttga
     2701 taatgccttg gtaaggaaga caattgaatt ttttgcagac aataagtaac taataaggaa
     2761 agcaaatgaa tgctcatctg ttggcatagt atgaaaaaag aattgatttc ctgatcatag
     2821 gaaatagctg gcttactatg ttttagataa tcaattttga actgttcatt tttcagaaaa
     2881 gtaatgatag atgttatttc ttgatctata gaaaaagatt gtcccgtaat atgtgctaat
     2941 aattgctcat caaaataaaa ctggataatg ataaaagttt gtgtttcctt ttgagtagaa
     3001 aagatttgga cttcttgctg tttatcaatg aataaaaggg aaggattatc tagttctata
     3061 gatttatgtg caaattcagc atataaatta gcgctttcat ttattagtag tcgaaaatag
     3121 ggagcagcag ataaatgaag atgggtatct atggaatagg ttagtgtttt tttgacaaga
     3181 ttggaggatt ggttgtttgt taacaaaaga accactttcc tttctctttt tatataaaaa
     3241 gctttctatt tataattaat gactattata acaaaaatga aaagccaaaa cgacaagtaa
     3301 aatatttttt tatataaata tttgtgttac taattccgtt aatatacata agtgaaagcg
     3361 ttttatataa gaacttgaaa agaaagaagg gatagacatg aaaaaaagat acaaattggt
     3421 gatagctttg ctaaacatta ccctattatt cagcttaagt gcatgtggaa aaactaacga
     3481 agaagtaaca gcaaacatcg cagatccaat gataaaaaaa gccactacat tagaagtata
     3541 tgtcgcaaac ggcaaactga caaactatgt tgaaaatgct gcaaaaatct ataaccgcaa
     3601 aactggagca aatattgact taaaaattgt gaatgtagct tcgggaacag caacagtaca
     3661 aatgatcacc ccaaaattgg taacacacga agatatgccg gatattatct ccatggcaga
     3721 cacttcagca gcaggtgtgc tggaaaaatt tcaagatgct ttttatagtg ctgatgaata
     3781 tggattttat gacaaatatg gcgatcagtt ttatgatcaa aaattgaata ttttgcgtca
     3841 acaaacgagt aatgaaacga ttattccttg ggctagtgat tttaccccag cactttgtta
     3901 ttatcaacca aaaaaatttg ctgaaatagg tgtagatttt gaagaaatca gttcttggga
     3961 agaatatatc caggtggcaa aagcattaaa agaaaaaact ggtagttttg gaattgcctt
     4021 gccagaatct ggggaccaag aattgtttat caacatgcta gcccagcaga atcaatcttt
     4081 gcttgatgaa gaaggaaata tccgtctgaa tactaaagaa gcgaaacatg ctgcaaagtt
     4141 aatcaaagaa atgatcgact cagatattgt acatttctac ggtgcacaag atgctgagaa
     4201 agcatttcaa gaatctgcaa tgtttgttgc tggcggctgg tatgctacga atatgtcttt
     4261 gaattttcct gatgcatctg acaaatggcg catggctcca ctgattcctt tttcaaaaga
     4321 aaatccagga aaaggtgcag tatcaggagg atcaagtttt tatgtcccta aagatgcaaa
     4381 aaatccacaa gtggcacaac aatttcttac atttatgctg acagatgaag aatgcttagc
     4441 caacgcactg gagctgggcg tggctacatc taactcattg gcctatcaaa cagaagcagc
     4501 tgagaaaaag tttgactact aaggaggaca aaaatactat gaactattga ataaaatcaa
     4561 tgaaaataca tcaaatactg ttttaccagc cacttattca gatgctacgt cttatttgac
     4621 taccgctgca tataactatt ggcaaacagg tgattttgaa aattcatatc taaaagaagc
     4681 agaaaatttt gctcataagt acggcgtaaa attaactggt gattaaaaaa tattaggagg
     4741 acttaacgat gatgcaatct tcgttaccaa gcaagacaat aaagaacagc aagaaaaaag
     4801 caacagatac gtctcataaa aaaagtgctt atggattggt cacacctttt gttattttct
     4861 ttattgtgac gattttgatt cccatcatta tctcgtttgc ttttagtttt atgaaaattg
     4921 gctactcatt tgaatttgtt ggatttgaca attatctagc tatcttccga gatccattgt
     4981 ttattaaatc ttacacgaat gttttgatta tcatggcagg atcaattcca ataacgatgc
     5041 tattagctat ttactttgct gttttattga attcagcaca gttaaaagga aaaggatttt
     5101 ttagaactgt ctattatatt ccaaccatta catcaacggt ggctgtagct tccgtattca
     5161 tgactttttt caatccgact gggttattca atggattttt gaatgcgcta ggaattaacg
     5221 gtgtacagtg gttaacaaat cctttttgga tacgaatatc aatgatcatc acgatgattt
     5281 ggcttagtgt aggatataac actattttat ttttagctgg tcttcaaggg atttctaaag
     5341 agatatacga aagtgctgaa atagatggag catcgaaatt tcggcaattc tttttattaa
     5401 cgatccccat gctaaagcca atcattttaa tggccacagt tttagccact atcaatggct
     5461 tgggtaattt caatatccca aatatattct ttgggacttc caatggacca gaaaattcag
     5521 ctttggtcgt aggagtcaat ttatataaaa caagttttga aatggttgat tttggaaaag
     5581 cctctgctat tgcctggacg atggtgtttg tatctgttat attatcggct attcaattta
     5641 aattcggagg tgataaaaat gactaaacaa aagatacaaa gcagaatttt tacgtacgtc
     5701 attattgtgt ttggtgcctt aatatttttg atgccatatt tatatatgat tgtagcttca
     5761 acgcaaagta atcaagaaat tttaagtggc ggaatcaatt tcaagtttgg ggatatgcta
     5821 ttaaaaaact ggcaagccat catggcgaga tataattatc ccttgattat ttggaattcg
     5881 attgttattg ctgtaatcag tacagtttta gctacagcca gttctacaat ggcgggttat
     5941 gcattagcaa agtatcgttt tatggggaat aaactgttgt tcaatacagt tatgctatct
     6001 aggatggtgc ctttttttac cacattgatt cctttatttt acattatgag tcgtttagga
     6061 ttatcgaata cttatgcagg tgtgatcatc ccttcgattg ccagtacaac ttcagtgttt
     6121 atgatgcgac aatatagcag tcaatttcct acagcactga tggaggctgc cagaatcgat
     6181 ggtgccaatg agtgggtgat ttttacgaaa atcgctgtac cgattttatc acctacgatt
     6241 attactagtg gtttacttat ctttatggga agttggaatc aatatctatt tccattagtc
     6301 atgctttcag ataaagataa atatacggtt cccttaatta tcaaaaatat gacggtttct
     6361 agtacaggtg agccaattaa ttatggcgca attatgctaa ttttagcaac ttcagtgatc
     6421 ccaatggtct tgatttatgt gtgggcgcag tctaaattta aggagaatga cattggagct
     6481 gcaaataagt aaaaaaaata acgaatgtta accatctagt tcgttctagg agcaactcca
     6541 cattcataaa aattaaaaga atggcgggat atccatgaat gaacagacga aggaatggtc
     6601 aagaaaaatt ttgaatgtag cttctgaaaa gatagatgcg gaattagaca gaatggggaa
     6661 taaaattcca tatatttctt acaacggaaa atatacagac gtaataaagg acagaggaat
     6721 cgactggtgg accaatggtt tttggagtgg tattttatgg cagctctttc acaagacaaa
     6781 acgagaaaag ttcaaagagg cagcaataca acaagaacaa ttattagaat ctgccctgta
     6841 ccatttttca gacgttcatc atgatgtagg ttttttattc ttaccatcgg ctattgcaca
     6901 ttatcaacag tctcaaaaca aacatagtcg acaactaggg ttacatgcag ctacggtact
     6961 tgctggacgc tataatattt cagggaacta tttagtagca tggaatgacc ataaacctgg
     7021 ttggatgatt attgatagta tgatgaattt accattactg tattgggctt cgagggaaac
     7081 tggtgatccg aggttctcta aaattgctcg gcagcatgca gatacaacag ctaagtatct
     7141 agtgaggaaa gatggatcaa ccgggcatat cgcagaattt gatgcagaat cagggaaata
     7201 tattcggtta cttggcgggc aaggatacaa tgagaattct tgttggagca gaggaaatgc
     7261 atgggcttta tatggattcg cgttaagtta tcgttacaca aaaaatccgt actatctagc
     7321 tatagcagaa aagatagcag taaattttat tcagaaaatc gaaaaaactg gttatattcc
     7381 tctcattgat tttgctgtaa aagattcgaa tattgatacc agtgctggag tatgcgctgc
     7441 atgcggtctt ctggaattag caggatatgt ttcctctgta cgatcaaaaa tgtatcatga
     7501 agctgctatc aatatactcc aaaagacaga aaagcactat gcaaattgga atatggatga
     7561 agatgggatc attggaggcg gagcagaagc ataccataga gaactgactt ataatgtgcc
     7621 actgatctat tctgattatt tttttattga aggcttactt cgattagaac agtcggaatt
     7681 agctatttgg tagtaaaaag aggagaaaat acaatgaaac atccagtacc actattaagg
     7741 accagacagg attactttga cttatttaaa aagataaatc aaccactcca gccgttttat
     7801 cgagcaagtg gcgcacaaat tgattatata catcaagggg taggatatgg aaataaaatt
     7861 gcaggaatgg aaggattctc tcgggtttta tggggagcgg ggcccgcaat tgaccaatta
     7921 gatgaacgat ggttgaaatt aattctatca ggaataaaag ctggaacaga tccttcccat
     7981 cccgattatt ggggagaaat acatgaaaga gaccagcgta tggtagaaat gcccgcaatg
     8041 ttattagcgt tatatcatca tgaacaatta ttatggaaaa aattagatac aggagaaaaa
     8101 agccagatta ttcattggtt ctcgcaaatt tttgaatatg aatgtgcaga tggtaattgg
     8161 caatttttta agataattgt cggaacaatt atccaaaaat ttggttatcc agttaaagaa
     8221 tcagcactga aagaagcatt tgataatata gaaaattgtt atcttcaaaa tggctggtat
     8281 cgagacagtt caagaggtcg ccaagattat tataatcctt ttgcatttca ttattatggt
     8341 ttgatttata gcgtactaga accagaaaag cccattagcc agatatataa gaaccgagct
     8401 attgattttt ctagagacta tattcatttt tttgcggaag atggtgcaaa tgtgcctttt
     8461 ggtcgaagca tgatttatcg ttttgcagtt tcaagctttt ggtcagctat gttgtgggcc
     8521 gatcttttgc cttttaaatt aggtgaaatc aaggggttag tcaatcggaa tataagatgg
     8581 tggatgcaaa aagaaatatt tgatgaaaaa ggtatcctga atattggtta tacctaccct
     8641 caattgacat tgactgaacc ctataatagt acgttatctc cattatggct gaataagatt
     8701 tttttattgt tggcgctacc tgaagaccat gagtattgga cggctaaaga aatgcctatg
     8761 cctattcgtg aaggaactaa acttctttca gaagccaatt tgctcataca acatgataat
     8821 ggacatacat tttttttgaa tgcgggacaa ttagggccaa atttccatac attgaccaat
     8881 gaaaaatatt taaaatttgc ttattctagt caatttggtt tttcgatacc gcgagcgaat
     8941 caattgaaag cagaaatggc aatggattca atgctaggga ttcagcgagc ggacacatat
     9001 atcacgacca gttttaagaa tgagagcatc aaaacctatg gacagttcat cgttcgaaat
     9061 aatgtacgag acattgtatg taagaaagag gtacttgcct ctacatggga acctacttta
     9121 caggcaaaaa tcagaacttg gcttattcct tttgaaggct ggcagattcg cgtacacaaa
     9181 gtagaattag atacagaata tgttctatat gagacagggt ttgctattga atgttctcct
     9241 gagaaagaag gaataatcat agaagaagac aaggaaaact atagggtgag tgaagctggc
     9301 ttttcaggta ttatctgttt aagtgacgat actattaaac gaaaatccac agctattatg
     9361 ggtttgccca atacaaactt gatgacatgg gaaaacactt ttattcctgg attagagggt
     9421 acatttggaa aaggaaccca ttggctcgga acaggagtgg ttgctcatca agatcgggat
     9481 tatagtttag aagtatggaa caatcgtccc aaaattgatt ttgatgggac aaccgggcta
     9541 actatccaaa ataaaaacaa taaaaaaaga ctaaaattat gctaaaggct ggtggggaaa
     9601 tgcttgataa agtgatgttt gaagagataa tacatccaga aaaatggata aatgaatgtt
     9661 ataaagaatt aatggaaaaa gaatggaata atgagatcga gcgttgtcgc agacacacgg
     9721 agaggttaat caaacgtatc agtaacagtc agtatcaatt cccaagcgag tgtcctataa
     9781 aaggacgtta tccattaaga gacaatattg gttggacaga aggattttgg acaggaatta
     9841 attggttgtt atttgagaag acgggtgatc ctttatttca acaaacagct gaaaaagcag
     9901 atatagattt tatccacagg attgactgtc aaattatcac taatcatcac gatcttggtt
     9961 ttttgtattc tttatcaacc gtagcagatt ataaaataac gggaaatcga aaaatgaagg
    10021 aagcttcaat tgatgctgca gaaacattac ttcagcgttt ttgggagaag gcaggagtta
    10081 tacaagcttg gggagatcct agtgatcctt cacaacaagg tagaatgatc atggattgtt
    10141 gcatgaatct tccattattg tattgggcga gtgaagaaac tggaaatcaa aaatataaaa
    10201 aagctgctca ggctcatatt caaaatgcag cagattattt agtaagagaa gatggttcaa
    10261 cttatcatac attttatatg gatgtcaaag atggaaaacc aagatatgga agtacgcatc
    10321 aaggttatag tgataattcc tgttgggcta gaggccaagc atgggggatt tacggttttg
    10381 cattaagtta tcgttatttg aaagaacaaa aatattttga tttaagcaaa atattagcca
    10441 attattttat gaatcggttg ccagaagata ccatttgtta ttgggatttg atctttgatg
    10501 attctagcag agaagaaaaa gatacatcta gtatggtgat catggtttgt ggattattag
    10561 aattaataga atcaggtcta ttagacaaaa cagaaaagaa cttataccag tctgctgttt
    10621 ggaaaattat gcgacaattg aaagaaagat atgctacaac ggaagaagaa gatggctttt
    10681 taacacagtc tgtttataat aagcccaaaa ataatggggt aaatacacct tgtatttggg
    10741 gtgattacta ttatttagaa gctttagtga gaatgactag taattggtct tcttattggt
    10801 gaaaaaggta aatatggaat ttttgtttga taaaataaaa aaagaaaaac caaaacagca
    10861 tgaatggttt ctgttttggt tttttcgtta attttcatat tcttctaatt ccaagcttag
    10921 ttcttcccat tccgtcaatt ttgtttcttg atcttgtcta gcagcttcta aatcttggtt
    10981 cagctcattg agttttacgt gatcttccag gttttctggc gcgaccattt cttgttccaa
    11041 ctgatcgatc cattcatcga tccgcgccat ttcttcttca acctgagtaa tttttcgttg
    11101 aaggctacgg ataagctttt gctgttcttt gctttggtaa taatcagatt tgttcgtggg
    11161 agcaggagca gattctggct catcttgtgc caacaattcg gcgatttctt cttcttcctg
    11221 ctttttctct aaataataat catagtctcc tagatagact ttgctgccat tttcagagag
    11281 ttcgacgact tttgtcgcga tccgattgat gaaatatcgg tcatgggaaa caaaaagcag
    11341 tgtgccgtca taatcgatca atgcattttc taatacttct ttgttgtcaa tatctaaatg
    11401 gtttgttggt tcatccaaaa tcaaaaaatt ttctttgttc atcgctaact tggctaaagc
    11461 aacccgtgct ttttcaccgc cacttagcag agggattggt ttttctacat cttcgccaga
    11521 aaataagaaa gcacctaaag cacttcggat ctctttttct ggagtggtag gatgctcatc
    11581 ccacaattct gctaggatcg tcttgtttgt atgcagatca gcttgacctt gatcgtaata
    11641 gccgatggtg acatttgtcc ctagcgtttc ttttccacgg ataaaaggga tctggtgaat
    11701 gattgatttc agcaacgtcg atttcccgat accattcgga cctactagag caatcgcttc
    11761 ttgacgacgg atatctagat tgattggttc agataaggtg acattatcat atccgatagc
    11821 ggcatcttcg atttgcaaga ctacatttcc agaaggcttt tctatactga atagaaagtt
    11881 tgcttgtttt tcatcccctt gaggacgatc cagccggtcc attttttcta atgtctttct
    11941 gcggctttgc gctcgttttg tggtagaggc gcgaacaagg ttccgagcaa cgaagtcttc
    12001 taatttatgg atttctgttt gctgcttttc ataagccttc cattcacttg ctaactgttc
    12061 tgctttcaaa tctagatatt tcgaatagtt acctttgtaa tggcgcattt ttcttctgct
    12121 taattcatag acttcattga ctactttatc taaaaaataa cggtcatggg aaacaatcaa
    12181 taatgcacca gtatagcttt gcagataatt ctcaagccag gaaagtgtct cgatatctaa
    12241 atggttcgtt ggttcatcta gaatcaaaat gtcagggtgt tgcaaaagca tgcgagctaa
    12301 agctaaacgt gtgcgctgtc cgcctgataa agtatcgatt ttctgatcat aaaatgaaga
    12361 atcgaattta aacccatgca atacggaacg aatttcattt tcataaccat agccgtttcg
    12421 atctgaaaaa tcgtgttgca gccggtcgta ttcttttaaa taagaactat aagcaggtgt
    12481 gtctggcgta ccttcgctaa tgaaaatctc tagctcgcgc atccgctctt ccatttgtct
    12541 aacttgttca aaagctttca gcatctcgtt ccaaactgtt tcattggaat caagtcctgt
    12601 gtcctgagcg aggtatccga gagtcgctgt tttattttta gcgatctttc cttcatcagg
    12661 tgcttcaatt ccagcaatga tctttaataa agtcgatttt ccagcgccat ttctgccaac
    12721 taaagcgaca cgagcgcctg tactgatttc taaatgtatg ttttcaaata agacttctgc
    12781 accaaaatgg cgagcaatct gattggcttg taataatatc atggaatcct cttttctact
    12841 ttgtgaattc tcctcaaata aaaaactatt tttcaattag tagtctacca taaattccat
    12901 tatactgcga gatttgcaga aatgataaat aaatgaataa agaataaaat ttcacaatat
    12961 ctgagcaatg gaattgattt tttcctataa atactgctat gatggagaaa tcaaagatgt
    13021 aattagacaa tacgtggagg tcatttcgtg aaagatcata ttattccaaa ggcgacagct
    13081 aaaagactgc ctttgtatta tcgctattta aggattttaa ataatgctgg aaagaaaaaa
    13141 gtgtcttcaa ctgaattaag tgaagccgtt caagtagata gtgcaacgat ccgtcgagat
    13201 ttttcttatt ttggcgaatt aggaaaacgt gggtatggtt atgatgtaga agatcttatg
    13261 cacttttttg caaagacatt aaacgacgat caattgacaa atgttgcgct gatcggtgta
    13321 gggaacttgg gaagtgcttt actaaaatac aaattccatc aaagtaatag catacgtatc
    13381 agttgtgctt ttgatgtgaa tgaggaaatc gttgggcgca tcgtagacgg tatccccgtt
    13441 tatccaatgg aagatatgtc agaacaaatc aagatccaac aaatcgaagt agcaatttta
    13501 acgatacccg ctgaaagagc acaagaagta gtcaatcagt taacggaagc aggaatcaaa
    13561 ggaatcttga actttaccgc tgctcgattg aatgctccgt cagatgtatt gatccaaaat
    13621 gttgatttga cgaatgaatt gcaaaccttg atctatttct tgcattctga cgcaaatgcg
    13681 cattccgaaa atacagcaga ataaaaataa aaagcgattg aacaaatgaa ggcaaaactt
    13741 tcacttgttc aatcgctttt ttctgtttgg acaacgatta ttttgttcgg aagatttctt
    13801 cataagaaag ggaatcatct tctgctgtca gttcatctag tagataacgg atttttttaa
    13861 agtcgatgaa ccgtgcttgc cgaaagactt cttttccttg atgaaaaatc aggacaactg
    13921 gcgcagtcag cacttcaaat ttactagcta cttctggtgt ttcaaatgca tccaaatgaa
    13981 gtgccggaat atcataatgt gtgagaagtt cctctagtcg tggacgaaca gcgtgacaaa
    14041 cactgcaatt aggcatcgaa agataaatga cggcaacgga tgactgttgc agtatgtctt
    14101 gaacttcagt caagttagtg gtttgtttca tttttattct cccttttatg atagaagtga
    14161 tatgtatgag accttaattt aatgggaata acagaaaaag tcaattgaag tgctttggta
    14221 aaaaataaga gttgtgtaaa aatttacaga gcaacttgtt ttttttgaat aaaagcgtat
    14281 atttgcaaag cgaatgaact agaaataaaa aggaggaaac tcatgttttc ttttattcca
    14341 aattcggttt tgcagatgag tacgattttc ttatcgatcg ttattgaagc attacctttc
    14401 gtattattag gctgtcttat ctcaggcgcc ttacaagtat ttttgacccc agaacgtgtg
    14461 aagagatggc ttcctgaaaa tcgtatcttc tctattttta ctggttcgat cttaggattt
    14521 ttctttcctt catgtgaatg cggcatcgta ccgatcgttc atcaatttgt taaaaaaggc
    14581 gtaccagttc acacagcgtt tgcttttatg ctgactgctc cgatcatcaa tccaatcgtg
    14641 attttttcca cttttatcgc atttggcaat tcttggcaga tggcaagctg gcgggtgata
    14701 ggcagctttt ttgttgccct tgtgattggt gtctggcttg cctattttca aaaagacgct
    14761 gtattgaaag aaaaaatcac gtctaaagta gcagaaaatc accatcatca tgtccatgaa
    14821 gaagaacaaa gtgagaagaa tgaaccaaaa aatcagctga tccatcaaac tgggcatgtg
    14881 ttgacacatt caatcgacga attttttgat acaggtcgtt atttgatcat tggcggatta
    14941 atcgcagctg cgatgcagac ttatttacca actagaatta tgctaacgct cggctcaaca
    15001 aagattttag ccattatcat catgctgtta ttggccttta cgatgtctct ttgctcagaa
    15061 gcagatgcgt ttataggatc ttctttgtta agtctgttcg gcacagcacc tgtagctgcc
    15121 tttttggtct ttggcccaat ggtcgatatc aaaaatctac tgatgatgaa acgatatttt
    15181 acaggacgct ttattttatc gctgatcgga ctgattgccc ttagcgttat tggattcaca
    15241 ttatttattt aggagggaaa atatgctgcg gtttttgatt ttatctgggt atttcgaatt
    15301 gatgatgtac ttgcaagttt ctggcaaact cgatcaatat atcaatgtcc attatcgcta
    15361 cttagctatt ctttcaatga ttttatctgc tcttttggct ttagttcagc tgtatttgtg
    15421 ggtcaaaaac ggaaaagcag aagaaaaggc acacgagcac gatcatgacc atgggttgtc
    15481 aaaaccttat caacgtggaa tcgcttatgt actgctagct ttgccagtaa tcgtggggac
    15541 gttgtttcca acagttagtc tcgacactac gatcgtagaa gccaaaggat ttaatttccc
    15601 agtaagtaaa gaatcagtag gggatccgga gatgcagaca caatacttaa agccggatac
    15661 cagtatttat ttcaacaaat cagactactt agaccaaatg aatgagttga aagaaaagta
    15721 tggggataag caaactatca agatcacaga tgaaaactat ttagaagtta tggagctaat
    15781 ttataattac cctagcgaat tcattggcaa aaaaatcagc tatgaaggat ttgtttacca
    15841 aacaccgaac gatagcaata cagatatctt cttgttccga ttcggcatta tccattgtgt
    15901 ggcagattca ggagtctttg gtttgttgac gcatatgccg gaaggagtaa cggttaaaaa
    15961 tgatgaatgg tataaaatag aaggaaccat ccaatcagac tattatcaac cattcaagcg
    16021 tgaaatccca tctgtagttg ttacaaacgc tgagaaagtc tctgctccga aaaatcagta
    16081 tgtgtatcgt tctttttaaa agaacaaaat aaataaacat agctcagaca gctgacacgc
    16141 aaggacgtcg gttgtctggc tttttttgca tgatgtattc atttgtttga tatttatttt
    16201 agaagcagca tcctgaaagt atttgatatc ggtttcaaag gtgttggaaa agattgtgaa
    16261 gagaattaca atttattcct aacatgtatg ttgaaaagtt gtatgaaatg attttgatag
    16321 taaaatatcg agtggaggta ctttttatgg taacgcgtat atttattttg gatgatagtt
    16381 tggtttttga aaaaatgcta gtagaaattt tggaagaatc cagaatttta ttaagtcctt
    16441 ggaaatttga gatcgttcag ggattgaacg ttatacaatt tgttgaattc attaaaaata
    16501 atgaaatcta ttcctcagat atttttttcc tagacatcga tttgaacgcc tattatagcg
    16561 gtatcgaact aggcgaaatg cttagagaaa agaatgaaaa gtgtaaaatt gtttatctaa
    16621 cgtctcatcc gaataaagca ataactgtta ttaatcgaaa gattacgcct agtggttatt
    16681 tgataaaaga attcacttat gaaaaaaata aaaaaagcat ccaaagttac ttattgaaag
    16741 aaaaagaaaa ctatcctgtt caacatgcta cgaaaaaaag gtggacaact gtccgttatg
    16801 gtaatagcga tcactatatc cattacgatg aaatccttta tctaatgagc atgccaggtt
    16861 ataaaaataa aataggccta gtattgaaag atgaagagat tctcgtaaac ggcacaatta
    16921 aaaaatataa aaaatcactc gaatatgagt atttatgtaa agatttaaaa gcttatatca
    16981 ttaatactga aaacattaca tctattagca gagtaaacga aatagtaaca tttgcaaatg
    17041 gagaacaact agagatggga aagagaagta ttgataaact aaagaatttt atgcaagaaa
    17101 agatagaaaa tgaatcattt taaagaaaac aaagactcat atcttacctg ttagaagagt
    17161 gttttcctgt agaagagaac aacccaagta gcagcctagt cgtttctatc cttttttgtt
    17221 atgcactctt tttgacattt actccaccaa taacgaaggg tacaataaaa agtaataaca
    17281 aacaaaagga gtacagaaat gattgaattc atcaatgtaa gtaaaagtta cgggaaaaaa
    17341 caagcattaa aagacttgtc tctctcgata agacaagggg aaatttttgg atttttagga
    17401 cataatggtg ccggaaaatc aactacgatt aaaagtttag ttagtattat tgaaccatca
    17461 tcgggaacga ttttagtaga tggaatgaaa ttgacggaaa atcgattgag tatcaaacaa
    17521 aaaatcggtt atgtgcctga ttccccagat atttttttac aattgacggc tggagaatat
    17581 tgggacttga tttcagctgc ctatgaatta gacacacaaa aaaaagaaaa gcgtttagca
    17641 gaattgacag cgctttttga tatgtatagt catcaaaatg aaacaatcgc aagtttttca
    17701 catggaatgc gtcaaaaaac gattttgatc ggcacgttgc tgccagatcc agatatttgg
    17761 gtattggatg aacctttgca aggacttgat cctcaagcag catttgattt gaaagaaatg
    17821 atgaaggctc atgccgcaaa aggaaaaaca gtcatttttt ctacacatgt attggatacc
    17881 gcacaacagt tatgcgataa actggctatt ttgaagaaag gtgaattgat ttatcagggg
    17941 gcagttagtg aattattgaa tggctcacct gatgaaacgc tagaaaagat ttatttgaaa
    18001 atggctggaa ggcaagcgac aggagatgga ccgtatgtat aagcgacaat tattagaatt
    18061 aattcgagtt aatcttttat atgttaatcc acagctcacg aataaagcaa gagagaaagg
    18121 aaaaaaggga aagcgattaa ctatctatct tttgtctcaa aatctttttt cagggctgat
    18181 ttttttactg atttacggat ttgctatgtt tgctatgaac tttgttaaat tgccaggttt
    18241 ctttacttat tacgtggcac tttttggtat gttaggttta actcaaagta tatcagtcat
    18301 ttataatatc ttttttgaag gaaatgacct gcaagtattt ttgcctctgc cttttggaca
    18361 agaacaggtt ttttcagcaa agattttggt agttgctttg accatcattc cttttgtttt
    18421 tccgcttcta gtcatgttta ttttaaccgg atggcgagct gatctaggga ttttgcttac
    18481 tatcattatc tcaatccttt tgttttctct atttttgatt attctttttt gtctggctag
    18541 tttgattgtt tttggtttgg ctcgaacagc agtgtttaaa aaacatagaa aaacagtttc
    18601 tagtatcttg cttggcagct cgatgctgat cgcatttgct ggaatcatgt ggatgaatca
    18661 tcaaacgggg actattgaaa atgagttaac agatcggcat ccgatttcga tattattgcc
    18721 attctatgat gctgccagtc agccactttc tcaacaaggt ttattgggtt ggggaatact
    18781 agctatcacg gctctgggat ttttccttgc tgtaaaacag ctgatagtac caaagcttac
    18841 agagcaactg actgattcaa acagtgagtt caaaataaaa agaacccata aaaagaacca
    18901 aaatgtgcat cagcttttat ttagttacaa tgctcaatta gtaaaagaac ctaatttgat
    18961 tatgcaagtt ctttcttctt ccttgttaac tccaatcatt tttattcttg cttttgccct
    19021 aggaggcgaa ataaaattaa ctgatttaga taataagtta atcggtgttg ttttcctggt
    19081 agggatcgca ttggctttct taacagttaa tcagacttct tttatcagca atcttatttc
    19141 tttggatcaa gaaaattttc tgtttatccg ttctttgcca atctctatga accaatattt
    19201 aaaagaaaag ttcagattcg gatggatatt gcagagtttt ttaactggtg ggatcgcatt
    19261 attaagcgga ctgtcttttc agctgccttt gttttttatc cctagcttgc tatttggttc
    19321 tttattcggc tgctacttat tgtcactacg ttatttcgct agagattatc ggttgctgct
    19381 gctgaactgg accaatatta accaattatt taacagaggt tcaggaagtt tgggtttagt
    19441 cgcaactatg atgggttcat tgatcatcag tattattctt atcgtcttat acggaatgtt
    19501 ggctttgttt tatccatttt ggttagtgaa tattcctgtg atcggtttag ttctaatact
    19561 ttccgctcta tggatcgttt attatcaacg aacgttttgg aaaaaatttg aataaagaag
    19621 aggggccgtg acaaaaatca tgtcgcagcc ccttttttac agatagaggg tgttcaaaag
    19681 tcagtttctc agtattaagt caattttatg taaaaatgtg agaagctatt tttacaaaac
    19741 tttttttaat actcataatt acttcttatt gctcctgcgg ttacttgtcg caatgtttgt
    19801 gagatatttt gtcatcgctc aaggctgaac gtctctttca caaccttttc tttgttacac
    19861 ttcgtttatt taaaaagccg tttttttcgt ttcatcatga ttgcgtcacg ctttactttg
    19921 aaattacgga tgttatggtt aaagacttct gataatacaa gacctaaagc gattgctcca
    19981 gcaatcataa ttgcttggac cgcataatga gccgcttctc gataggattc agtaacgaga
    20041 tttcgaaccg cttgataagc taaaccacca gggactagag gaaccatccc gggaatattg
    20101 aaaatcgtta cgggcatttt caaacgttta gagaaaagat cgctgatgaa tgctactcct
    20161 aaagaaccaa gcaatgaacc aaaagcagca gatccgccta tttgaacaca gatccagtag
    20221 atcatccagc caaaagcacc agaaagacca caacaaatca atgaacgcct aggtacattt
    20281 gtaataacgg caaatgccgc agtcgctaaa aaactaaaag aaaactgaat aaatatcgtc
    20341 cccatacttg tgttcctttc ctaataaaaa agctggaaaa taaaagcaat cgcaaaaccg
    20401 atcatcgtag cagtcatcat cgcttctgtt ccgcgagaaa ctcctgagac ataatgtcca
    20461 gctagcaaat cacggatagc gttcgtaatt tgaactccag gaactaaagg catcacacat
    20521 ccgataatga ttagatcctg attgcttcct aagccaaaac gtacgctgta gatagcggct
    20581 atgccaatca ataaagaaga taaaaattcc gataaaaatt tgattctaaa aaatttcaaa
    20641 ctatatagat aagctgcgta tcccaatcct ccaatgacta aagtcacagg taaatcggtc
    20701 atctttccgc caaataacac cataattgtt ccactgatca ctgccgcgct aacgatttgc
    20761 aaccagacag gaaagaaaga acggtctcgg tcgattgctt gcagttcgca gtaaagttct
    20821 tctaatgtta gctctgaagc aacatattta cgtgaaagat catttacttt tactactttt
    20881 tctaaattaa tcgaacggtt ggtaatttgt tccattcgga tggtcgaggt acgatcaaga
    20941 ccaataaaga gaccggtttg agtgacatag ctgaccaaac ggaaatttcc agaagctaaa
    21001 gcaattcgac tcatcgtatc ttctacccga tacatctccg cattgctttc catcatgatt
    21061 ttcccagcga gtaaacaagt gtccagcaac agatctaatt cttttcccgt catagcatct
    21121 tctccaataa ttgattgatt agttttattt tactacaaaa cataccagaa gcgtaaagaa
    21181 taaaaaaact tgaggaagga ataaaagagg cgtatactgt ttttgtattg cgggtgtagt
    21241 ttagtggtaa aatcccagct tcccaagctg atgtcgcggg ttcgattccc gtcacccgct
    21301 taaaataggt tgtgaaaaag ctgctctgca acaagtaata agaacagcca agcaaaaaca
    21361 acttcttatg tttttaactt ggatggactt attaccgcag atgcaagctt ttgcgcaccg
    21421 tttaccaagc ggttgtgaaa tcagtgtatt gtcttgagta tgaagaaaat ttttgaataa
    21481 taataaatac cttacagata gagtggtgac tgattagaga cgaggaatcc gtctcttttt
    21541 tgtattttta agccatctta aaacaggttt tattttttgc tgtttctatt tctttctagt
    21601 atttatttat aggggaacat atgttaagat ttagggagct gttagtaaag gagtaaagaa
    21661 atgagcaaaa aaacaaccaa ggcgatcgtg gggatcgtcg ctgctgtgat tgcaggggca
    21721 ttcggtgttt ccaccacaca aaaagattca gatatctttc agcagattac aactattttt
    21781 gattccacac cacaagcttc tcaagtagcg gatgtgccag aatatgatgg aaaacatcaa
    21841 gaaatagaaa tcaatgggaa tcagccggaa tttacaaaag aggatcttag cctttccaaa
    21901 ggaacatggg aaagctattc aaatattgat aaattgaaca gagtaggaca agccaatgct
    21961 atgcttggaa aagatttgtt ccctactgaa aagagagagc ctttgtatat tgacccgaca
    22021 ggttggaaac aaaagaaatt aagtgacggg caatggttat ataatcgcag ccatttaatt
    22081 ggtttccagc tgactggtca aaataacaac attaaaaact tgatgacagg gacacgttcg
    22141 ttgaatgctc catacatgct tgctcacgaa aatgatattg cggcatatat caaagaaaca
    22201 aatcatcatg tacgctaccg tgtcactcct cattttgagg ggaatgaact ggtagccagg
    22261 ggagtgcaat tggaagcaga aagcattgaa gacaaaaaaa ttgaattcaa tgtctttatc
    22321 tacaatgttc aagatggcta cacgatcaat tatgagacag gacaagcaac aaaaacaaaa
    22381 aattagtagc agctattcga attttttatg aatattatga aaaaattgtg taaaaacata
    22441 cattcaaaga aatatagcgt atactttatg aaaagagtac ttttgataaa gctacagaaa
    22501 aaaggaaaaa aacatacaaa tagtgtttct taatttattc ggaagtttgg aatatttgtt
    22561 tgtagttttc cctttcttcg agtaaaataa ggttgtagaa ggtaagctgg aattaccttg
    22621 cgggaaagag gtgtagaatc atgggtttta cagatgaaac cgtacgtttt ggttttgacg
    22681 atagtcgcaa aaaagaagtg agcgaaacat tagcgattgt ttatcgggct ttggaagaaa
    22741 aaggctacaa tccaatcaat cagattgtcg gctacttgct ttctggagac ccgtcctaca
    22801 ttcctcgtta tcgtgatgct cgaaatttga ttcgccgtca cgaacgcgat gagatcatgg
    22861 aagtaattgt caaggactac ctctcaaatc atggagtgaa tttatgagag taatgggctt
    22921 ggatgtcggt tctaagacag taggtgttgc tatcagtgac ccctttggct ggacagctca
    22981 aggagtagag atcattcgga tcaatgaagc agaagaagag tttggctttg atcggttgaa
    23041 ggaattagta gcacaatatg aagtagaccg gtttgtagtt ggattaccta aaaatatgaa
    23101 caattccatc ggaccaaggg cagaagcttc catgtcatac ggagaaaaga tcaaagaact
    23161 attctccttg ccagttgatt atcaagatga acgattaacc actgttcagg cagaacgtat
    23221 gctagtagag caggcaaata cttcaagagc caaacgaaaa aaagtcatcg ataaattagc
    23281 agctgtgatg atcttacaaa attatttaga cggctcaggt aagcaattat tttaataata
    23341 aaagaaaaga ggtaatctta tgacagaaca taaccattcc cacgaccatg aaggacacga
    23401 acacatcaca ttggtggatg accaaggaaa tgaaacatta tatgaaatcc tactaacagt
    23461 tgacggacaa gaagaatttg gacgtaacta tgttctttta tatcctgctg gtgtttcaga
    23521 agatgaagat gtagaattac aagcttatgc atacatcgaa aacgaagatg gaacagaagg
    23581 cgagttagaa caaatcgaaa cagacgcaga atgggacatg attgaagaag tattcaatac
    23641 attcatggcg gaagaagaag aatagactat aaagctagga gaaaccttga tatgataggg
    23701 tttctccttt ttttattttt tactgtatgc catattgtat gccatctagt caatatttaa
    23761 gtgttgtact aatttttcaa cagtcttttc tttcgtttct tttgccaagt gaccgtaaca
    23821 atcgatcgtc tgactaattt ttgtatgccg taatctagtt tgaacttcta ccatagtagc
    23881 tccagcgtcc aagagcattg aagcatgagt gtgtcttgct acatgcacac cgagaaatgg
    23941 aaccatagct ttttcacaaa tagtaatcaa tcttgcataa atagcgtggt gtgtgattag
    24001 ttctttatag ataccacaaa aaatcatagt cggatcagtt acaccaagtg tcagcatata
    24061 tttccgctga ttaatctgcc atttttttaa tatagaaatt gttctttcat ctagtggaag
    24121 aaccccagca ctacaatcag ttttaggatc actgatttta tagccatttt tggattggct
    24181 tagtgtttta ttgatggtga ccgtattttc ttgaaaatca atgtctgacc aattcaatgc
    24241 aagggcttca ctgatcctaa ccccgctata aaagagaaag cgtagtaacg ttttatcaaa
    24301 gtcgtttcga taagtttcag gtttgctgtt taggtaatca aacaaggtga tcagttgttc
    24361 tttactgtaa actttgacct tttctttatg cttagtggtg gttcttttag gcattaatac
    24421 gttgtctagt ggattagtct caataatccc aagattgata gcgtagctaa aaatacgctt
    24481 agaagttgaa tgaagtacct tgtattggtc agtagtttca gcccagctat ttacaatttg
    24541 ttgggctttt tttaccgtga cttcattcac acgaagattt ccatattttg gaagaatcca
    24601 ctttctaaac ttgatttcag ttttcatgaa ggtggcttct cggacagtgg ttttatatgt
    24661 ttctagccac aagtcataaa cttctttaaa cgtttcgttg ttcgcttttt taataccgtt
    24721 tttatcgtag tccacttgca agcgtgacaa ggcaagctgg gcttcttttt ttgttttgta
    24781 acctcgtcta cgaaccttat caggtttgcc agtcattttg ttcattccaa gataggcttc
    24841 atagagccaa aatttacctt ttttagtttc atattgcttg aatgttgcca taatagtttt
    24901 ccctccatag tgtagcaagc cgtgggggcg gttggaggag gcagtttatt attattttga
    24961 atagtgttta tttagctcag taacaagagc tgtgaactct tttagaagat cattttcata
    25021 aaattcttga tactcttttt tctcatctgt atttttttct gaatcattaa ttaatgagtc
    25081 atatcgtaaa agcgtattta gaagagctgc gagataagca attggggtac tcccgtcagg
    25141 aaattcaatt cgagatcctg ttttaagata ttttattgcg tttgttaaat aaatcttctg
    25201 tgagacagtc aggttatctt cttcgatgtt attgatagca ttagaaagat tagaatcaat
    25261 tatagagtta tttttttcaa tagttttttt caattgcttt tcaagcacat ttcgcttaat
    25321 ttcgggcatc atatgcatat ctcttaatgt ataagatccg tttaatagat aggtagtgga
    25381 tacatctaat acctttgaaa gttgtttaag cctggtgtta ttgggaagat tatagccatt
    25441 ttcccaatta ctaacggcac ctttactggc cggtggggat aatttacctc caagttgttc
    25501 cattgagagt cccttttcaa ttctagccag tctaattctt tgtcctgtct ccactgcttc
    25561 ggggtatttt tttctagcca cattttcacc accattcata tattttctct actatatcac
    25621 gatttaaata tgtgtgaaac ataaaagttc aaaaaagtat gttaaaattc ttgcaaatga
    25681 aaaggtatga tggtatattg agtttataag aggtatagaa atgtattcaa gagcctcttg
    25741 cattttttta aaatctttgt atagaaatgt atgctaacga ggggggataa atatggaatt
    25801 aaaaattgac aaactcacgc ttgatgatcc agcttttaaa attattgacg atcgagttgt
    25861 tcaacaagta gagcaaactc aaggaacgtt actttcatta ttagaaaaaa agtaccagtt
    25921 tccaaaatat atgaacaagg cacaagctgc taagtatatg aacgtttcat acaatactat
    25981 gatgcagaaa tatgttccta acggtttaaa gttgattata gttgatggag tcgtaagaat
    26041 ttcacaagat gaatgtgatc gctttatgga agaataccaa aaataaacgc aagccgtggg
    26101 ggcaaaggga ttaataggag gaaataataa tggaatcgac acaaaataaa gcaatcgaaa
    26161 aagtattatc aacaattctt acagaagaca cagcggcaga attagcaaac ttggaaggca
    26221 aagcgctaga agaaacgttt gaatgtttgt acgaacaaat ggactatcaa aaattgctac
    26281 cacaagaacc aacggtaagc ggagtattgc gtggcttgaa cgatttagta caagcagagt
    26341 ttaaagaacg actttctatt gaagagtatc aagaaatttt gtatcagcaa gttgagttgt
    26401 tagcgagctt gctagggctt gaactggagg acgttgaatg aaaactgaaa tttggaacgg
    26461 acacattata agatttgtcg atattaatga tgaatggtgg gcagtggcga aagatgttgc
    26521 ggaagcgtta ggtcttaaac aggttactag agccattcac tctttgccta aagatggggt
    26581 tactactagt aaggtcatcg attcattggg cagaacacaa gatgtaaaca tcatcaacga
    26641 aaaaaaatat ttaccgcatg gcattcaaaa gccgtaaaaa agaagccgag gcatttcaag
    26701 actggatttt cgacatcatc aaagaactac gccagtccac aggacttgaa ggctttcaag
    26761 tattccgcat gctagacaaa gaacaccaaa aagaagcaat gactaaatta agccacgcta
    26821 ttactgaacc aaaaccagta gactacatta aagcgaatgt gatagccaat aaagctgtat
    26881 caactattta tggtcattcc aaaatggtaa aaaagaaaga tatgactcct gaaatgttgg
    26941 ttgatcgtga acctatttta gatgagacag tagaattaat gactgttaaa gaaaaatatg
    27001 ggttgcagtt ttcagtgagt gagaaaattt ataatcgttc tgctgaattg cagacaactt
    27061 aggagcatta acatgatcga gaacaaagaa aaagccttat ccataacagt cttggcggac
    27121 aggataaagg caacttaatt gggataaaac ccgatattct ttgttccgat tataccatat
    27181 taaaaaatcg gagggaacca ttatgaaacg aaacttaatt ataggaagca ttttaatcgg
    27241 cggaattttc ggcttattac cattaattgc aaaaatagct atctttgcag gattagcgtt
    27301 atatctcttc actgcttatg acgagtacga ctatcaatta agaactggag ggcataagta
    27361 gatgtacaaa acaaaactat taaaccaact cgatagcctt gaattagagg aaattaatca
    27421 agggatcgct gaactagaaa ataatatcgg gaaaacctac tttggaaatt cattcaatga
    27481 aaaactaaca gttttgtatg tactcaaaaa acatgcagaa cacaaaataa tttgtcgaga
    27541 aatcaacgag ctaaaaaatc agattttaac cgcatggtta aacattactg atatgcaaga
    27601 agcaagggtg aaaacattta atacatgggt aaagtatcag aatcaattaa aaggtgctga
    27661 atttgttcgg gatgggttga aatacgaact tgagcagttg aagctcatgg aggtgtctga
    27721 atgatttata ccagtatttt gaaaaaggag gagaggttta ttggcaaata attatcaagc
    27781 agcaacggaa ttacaaaagt cgggatggtc aatttatccc ttatctcctg gaactaaaat
    27841 tccaataaaa ggctctagtg gttggaatga tgcaactaac gattctaatc aaattaatga
    27901 atggtggacg gaagatgcaa ctagaaatat tgggttaatg cttgaagatc atcaaatggt
    27961 ggtagttgac ctagatcaac attctgaaac acgaaacggc gttgagaatt ataaaaaact
    28021 tgcttcaatg tatgatccat ttccttctac ttatacggaa atcacaccag gtaaaggaat
    28081 ccatttcttc tttaaaattc ctgatggtgt aattatccaa caagaaacag gtgcatttgc
    28141 tgatatcttc gggcgtgatg ataaaggtaa aagtttaagc gggattgata ttatcactaa
    28201 aggagttcca atagcgccaa ctatgattat ttcaagaagt gttgggagag catatgaacc
    28261 tattgaaaac gtatctctaa ataatattgc accagctccc gattggctag tgaacctact
    28321 gctaaaaaaa ccgcaagaaa taaagactca ataccgaccc gtagcaaaaa cagggacagc
    28381 aaaaaaatta gatatgattg ttcaaggcgc tggcgaaggt agtagaaacg atcatttaac
    28441 taagttatgc ggttggttac tatggcacgg tgtagataat caaactttag cagaattgat
    28501 ttatacagca aatgcgtaca atgaaccacc gctaaaagat aaagaagtga atcaaattat
    28561 tcgatcgatg attaaaaaag atttgagggg gaaagctcat ggctcataag cataaattag
    28621 atagtatttt agactttccc gaagccagcg agcgtgaaga caatatcatt gaattgaaaa
    28681 cctggatgtc acgattaaga tgcaataaag acgatcagat taaaagtaac agtgttgtga
    28741 atgcagaatt gattttaacc aatgatagca atttagctgg aacaattgct tataacgaat
    28801 ttagcggata cattcaccta ttaaaagatt ctccttggat caatcgtacc gctggagaat
    28861 gggaagacag ttttgaggat gccttaacgg catatattga agaaaactac aatgtagttt
    28921 ttgatgacaa caaaatacac aaagcagtag taaatgtggc tagaaagaat gttttcaacc
    28981 cagtaaaaga acgtatcgaa aaagttaaat gggatcaaca gcctagactg gaaacactgt
    29041 ttattgacct tttaggggta gacgacaacc tttacacacg agaagtaaca aaacgttgga
    29101 tagtcggatc agtcgcacgt atctataaac caggaataaa gtttgagatc gttccagttt
    29161 tggatggacc gcaagggatt ggtaagagta ccgttccagc attactttac acggatgatt
    29221 ttttcaccga ttcattagat tcgctaggtg aaaagaaaga tgattatatg cagcttcaag
    29281 gcaatgtaat tattgaactt ggagaattat cttcaatgaa caaaactaaa attgaacaga
    29341 taaaaaactt catcagtgcc aagatcgata aaattagacc tccttatggt cggaatgtca
    29401 tagcttgggc aaggcaatgt gtatttattg gaacgtcgaa tgatgggcag tatttgaaag
    29461 atgatacagg aaaccgccgt ttttatcctt tgccttgtaa gaataagcca aagatgaatc
    29521 cgtttaaaac aaaggatgaa tattttcttc aagtgttagc tgaagcaaag gtgctttttg
    29581 ataaaggaca acgaatctat tttagtcccg atgaagataa agaagtctta gaaattgcaa
    29641 aagactatca agaggatgcc aagatggaga atccaattaa agaagcaatc actaaatatt
    29701 tggaaatgga aatcccgtat aaatgggaag aagctccagc gtgggcgaga cgttcttatt
    29761 atcagaacta tcctgacagt aaatgtaatg agaaaaattt acagcatttc tataatggag
    29821 ctactatgca acaagagttt tatttagttg atagcgtact caccgctgat attttggaag
    29881 ctgtttttga taaacaagca aaggatttat tgaatggtcg atcagatgca gaaactaaaa
    29941 agattgcctt gattattagc agtattcctg gttgggaacg gaagcaactg ccaaaaagaa
    30001 ataaacgacg aggattttac aataagtcaa atgcctatga aaataaaaat cgagctggaa
    30061 agtacaaaaa gtaacgggta gtaacgggtc agtaacacct agcccgttac tagtttaccc
    30121 ttactgcccc aagggataca gcaatttggt aacggggtaa caccttattt ccttaaaact
    30181 tttgaaatag ttagctaata tgctggggaa taatgttact ggattttacc cgttacctgt
    30241 taccaaaacg ctagaaccct tgtccccgtt gggattgagt ggtaacgggt acctgttacg
    30301 taggtgttac cacgtgttac gaatcaagga ggaaagtaaa tgctcaatat tatttcaaca
    30361 aacaaagcac cgaactttca atatacagat gaaatggatc ggtttctaat gaacacgctg
    30421 gcatttagtg tgggattggt aacagaagat tattccacat ttgatccaga agtattaaag
    30481 ataatggaag aagaacctga ttggctgcag gagtcagtag cgtggtgtca atcgctagta
    30541 gtgggatcat tggtagatag tggcaactat gatgatacag gtgagctaat ggatgaattt
    30601 aattgtctgc ttaacctata tgatcgagcg agacaacgag agcttacatc gaatgaggat
    30661 aatttgtttt taaacatcca tgataagttc ttggctttgc tactaacaga tgatgaattg
    30721 ataactaatt tattggaggt agaataatta tgcatatgga aagtattaga tacttcgatg
    30781 gtgagaaaca cattgagtat tcaaacactc aagaagatgt agactttatt agttttgagg
    30841 aagataaaat cactaaagtt aattttaaag acggaacgtg cttgaagata gtttcgcctt
    30901 atattgaata caaatcaaaa tgggaacaag atgattctga cgaacgagat cgctttggtt
    30961 ggtaatctat ggcagttaaa aaacaatgta atcatgctgg atgtaaaaca ttgattgatt
    31021 ataggcagaa gtattgtggg aagcataaag caaagcaaac ggcaattaag cgtgaagaaa
    31081 gaaagcaaag cgaaggtaaa tattttcaat tctatcaaag tagaacatgg cgaaaggctt
    31141 catacttgta tcggttaaat catccagtat gtgaggattg cctagaagaa ggcttgataa
    31201 ggaaagctga tgttgtagat cacaaaattg aactaaaaga tgattggaat agacggttag
    31261 atgaaactaa ttttcgttct ttatgccatg cacaccataa ttccaagaca gccaatgaaa
    31321 gacaaagacg agaaaagagt accctttgag ttaagggggc atagtgtgaa acttactgac
    31381 aatcgatgcc tactcatttt ggtacaaata accgttgtga aaaggcataa gggtaattac
    31441 aaataacgat tacacttgta atcacaagtg aaaaagtata taatgaaagt aggagattta
    31501 ttgaaaaata caattgttat tactgataaa acagggaaac agcgcaccat tgagttacct
    31561 cattttggtc aagtgaccat tcaaatgcag aacggaaaaa tcatttatat agataaatta
    31621 gataaagaaa aattctgatc gaaaaacgaa ggaatgtgag cttaattgct tacgttcctt
    31681 tttcttttgt ctgaaaggag gacaacatgg gacaccctaa aatattacac gatacaaaag
    31741 gcaatatatc aagtgaagaa aaagcaatcc gtgtggacgc tagagaagaa ttgttcaagc
    31801 agcaaccatt aataaatatc acgccccctg actggatggc agcgagcgct agaagtgaat
    31861 ggaatcgtat cgtaccaaca ttaaaaaaag attatccatt gagtgaagca gattatggtt
    31921 cattggtagc ctattgttta gcctttgctc gaatgaaaac agccgaagcc gagataagaa
    31981 aatcaggtac gtttatcaca tgcgaaaacg gagtaaagaa agccaatcca gcggttcggg
    32041 ttcaatcaca agctatgagt gatttgaaaa aacaagccac ctcactaggt atgaccttag
    32101 aatcacgatc aaaactagct ttgaacaagg ttaaaaatga tgaacccgaa gacccgttca
    32161 aagagttgat gaattcatga atgattacat tgagaaagtc ctatcaggta agctgattgc
    32221 acccaagaaa attatccaag cgtgtgagcg tcatataagc gatttggagc gttctaagtc
    32281 agatagcttc ccttatgtgt tcgatgaaga acaagccacc aaagcgatta aattcattga
    32341 gttgctacca tctacggacg gtaaagcaat caagatgtta ggatttcaaa aattcattct
    32401 aggcagtctt tatggctggc gtactaaaga agggaattac aggcgattca atcgagcgtt
    32461 taccagtatg agccgtaaga atgggaaaac gtatatcgca agtggcatgg ctgccaatgc
    32521 gttgattatg gaacaagaac cagcagaagc aaggcaagta ttgtttgtaa gtaacgcttt
    32581 gaaacaagct aaattgggct atgatatgct gtctaattca cttagaaacg tggtcaagtc
    32641 tagtaagttt ttaagaccac aactgaaaat tatgaactct aagattcagc acttgccctc
    32701 taattcgttc gctatggcac tggctagtga aaccagcacg ctagatgggt ttgcaccaac
    32761 aaccgcaatt cttgacgagt ggcacgaagc aaaaactcgt aaaacgtaca acgtcattaa
    32821 gtcaggaatg acccaacaaa agaacggctt attgtgtgtt attagtaccg ctgggcttga
    32881 tttaaacgtt cctatgtacg aggaatactt attgttagat cgtgtgctaa aaggcgaaga
    32941 acaagccgac aggtacttta tagcgatatg ggaattggac gatcccgaag aaattcacga
    33001 tcaagagaaa tggatcaaag ccaatccgat ttttgaaagt gaagaaatca aaaaagtaat
    33061 gattccaacc attcaagatg atgtgaacct tgctttgaaa caaaataacc ttaattctgt
    33121 attggtgaaa aacttcaatt tatggagaca agcgagtgag gacagctata tgattgctga
    33181 agactggcag gcaaccgaag tagaaccaca agatattaca ggcaagcccg tttatatcgg
    33241 agtggattta tctaaaacag atgatttaac tagcgtttca tggatcgtac cgctagataa
    33301 cggcgaactt tattgtgatt cacatagctt tgtagccacc aaatatgggc ttcaagacaa
    33361 agaaaagcgc gacggtttgc cttatcgaga actagaaaaa gctggtgagt gttccattac
    33421 tcaattagaa agtggaatcg tggactatga ccaagtattt cagtttattc aagatttgat
    33481 tcaagaaaat gatttggaat gtatggggat ttgttatgac ccgtataacg ctaattcgct
    33541 tatcagtaaa gctgaaaaag ccaactaccc aatgttagaa gtaagacaag gaacgattac
    33601 tctaaacgtt ccgacccgaa cttttagaga acaagtttat gaaggcaacg ttattcacaa
    33661 taaaaatacg attctcaccc atgcagtgaa caacgctatt ttaaaaacgg ataacaacgg
    33721 cattcagatt aataaatcaa agaacagtaa caaaattgat ccaatagctg cattaatcaa
    33781 tgcctatgtg tttgcaatgg attacttcac cacaacggaa ggagcgaaag cagacaatga
    33841 attttataca agtgaagaat tttctttcta attacattca taccgttctt ttacttcttg
    33901 gattggtgtg tgtgttggtt gctatcacct tactaacaaa tgtctactat ggcttgttag
    33961 cgctgggcat agtgcttatt ggggtagcgg tcatgctaaa tacagaacag aagggaggtt
    34021 aaaagatggc attttttaaa gcgagacaaa atacaacggg agatcctttc ctacaacatg
    34081 tggtatcaat ccaatcggat gattacacca ccagctttac aagcgttcgt gcattaagaa
    34141 atagtgatgt gtttgcagcc gttcgaatta ttgctagtga tattgcttca agtccgattc
    34201 aattggtcaa aaacaatatg ccacaagctg ataatgaact ggtgaagtta ctaaacgaga
    34261 aacctaattc agaaatggat ggttggcatt taaagtttgc tttggcggtc aatatgttgc
    34321 taaacggtaa tagctttgca gagattaaac gcaacggtga aaaggtagaa gaaattcact
    34381 tattacctaa ctcaagtgta acggttactc aattagataa tggtacgttg tcttatcaga
    34441 ttggtgataa aaaaagacgt gtgaagtcta gcgatatttt gcacttcaaa tatttcaccc
    34501 aagatggttt aacaggatta ccaccacttt atgcgttacg tgatgaactg aaaattcaac
    34561 aagctggcaa ccgcacattg cacaatttct ttactcgtgg tgtcagtggg tcaggtattt
    34621 tgaaggttca taagtcagat ttagacggat cagcaaagaa cgcaattcgt gaaaagtttg
    34681 aagaagccaa cggttcaagt agtggagata atgctcttag aacgatcatt cttgatgaaa
    34741 caatggacta caaaacatta gaaataaaca ccgatgtttt gaagcttatc aattccaatg
    34801 attggaacac aaaacaaatt gccaaggcgt ttggtgtacc gattgagcgt ttaggcgttg
    34861 aaaatgaaca ttctagcacc gttcaaagta atctccagta tatccaaagt acgctgattc
    34921 attactttaa tgtgtttgtg agtgaattag atacgaaact tgaaaccaat atccgcttta
    34981 attccgatca gttactagag actgatcctg aaacaaaagt aaaaaatgta ttggatcagg
    35041 tcaaagggtc acttctcacg attaatgagg ggcggtcgaa aatggggcta ccccccatgg
    35101 atggtggcga tcgtttacta gcaagtttga actttacgta tttagatacg ttggagaaat
    35161 atcaattaaa agaacaggaa ggagttacac cagttgaata atgaagaaga aaaggaaaaa
    35221 cggctgacag aagaagctga gctaacagcc gattctccca aagtagagaa agaaaatgaa
    35281 aaacaaccaa cagacggcaa aactatttca ggctatgcgt tgaaattcgg gcaaccgtca
    35341 aaagatttag gcggctttgt agaagtgatt acacccgaag cattaaaaga ggtggattta
    35401 tcaaatgtgt tcttattata tggacacgat tattcaaagc cactagctag tgtcaaagca
    35461 ggtacgttga aattgaatgt cgatgataca ggattacatt ttgaagcaga gctaaccgac
    35521 acgacctatt caaatgatgt gtatgagaat atctcaaaag gggttgttga ttctatgtcc
    35581 tttgggttcg tgcttggatt agattcattc gacaaaaaag aagatggcac aattgaacga
    35641 tcaatagata aaatcaaagc acttaatgaa attagtgtcg tgaccgttcc cgcttatgat
    35701 tcatcaaatg tccaagtaaa taagcgttct tacgaatcgt ttatgagtaa caaccaagca
    35761 aaacaaacaa acaatagctt agaatccact tctaaagcac aaaaggagag taataacatg
    35821 gaaaaaactt taatcgataa cgaaaaaaca gaattgcgtg ggtatgaaga atatatccgt
    35881 tcacaaggcg aagtgcgtga tggagtcact actgtaaatg cagcggcagt tgttcccgaa
    35941 gaagtaatcg gtgaagtctt tgatttgaaa cgttcaaatt ataacttagc tcaatatgca
    36001 acagtaaaaa cagtatcaaa tggacaaggt aaatatccag tagcaactaa ccaacaagca
    36061 gtgttagcaa caaaagctga acttgctgaa attggtgata ttgacgctga aatgtttact
    36121 tcagttgatt ataaagtaga aactcgtgct ggtaagattg ccttatcaaa tgaggttgtg
    36181 gaagattcag cagtgaatat tgtacaagag gtcaaagatc agttagcgaa attggtagaa
    36241 aacactgaca ataagcatat catggattta ttaaaaacat tcactaagaa aacggctgct
    36301 acgttggacg atttgaaaca actatacaat gtggcattag acccagcatt aaataaaatg
    36361 gtaattctaa accaaagcgg atattaccac ctagatacat tgaaagattc agatggacgt
    36421 tacattttac aacccgatgt gacagcacct agtggtaaat cattattcgg tatgccagta
    36481 gtattgattg cagatacatt gtttgccaat cctaaagctg gaacattccc tatgattatg
    36541 ggggatattg cacaatctat ctttgttgct cgtagaaatc aagtaacgac tcaatgggaa
    36601 aaattcgatt actactcaca aggacttgca gtgatcgttc gcaacgatta taagaaaatt
    36661 gatcaaaatg cttcagtgta tattgagttt acgccagttg taacaccaaa agtatagaaa
    36721 aatattgggc ggcggtttat cccactgcct ttttttcatt aggagagata aaatggtaat
    36781 tttggatagc ataaaaaaaa gtatgcggat cgatcacact attgatgatg actttattca
    36841 acaattgatt gatacagcag gcgaatatat aaaaagtgct attgatagta gcgcaacgga
    36901 taaagatatg gataattatc agcaatttga tttggcggtg tcattactta ctcaacattg
    36961 gtatttgaac cgtcaagaag ccagcagcga acggatacca gtaacggtac aagcattagt
    37021 acaacaaatg agaggtgctt attatgccaa tcattaagaa tgtaaatgaa ttgactgaga
    37081 gagtcaagtt taaaaagaca aaacgggtaa aagatgaaga tgggcagatg gtggatagtg
    37141 aagaaactgt atttgaatgt tgggctaatg tgcgttcaca aatgctaaaa gacgtgcttg
    37201 ctagtgtagg taccattctt gaaggaacgt tgacgtttat tattcgatac gatcaagatt
    37261 atgaactaac aaacgatatg aaagtagctt ggaaaaacaa gagttataaa attatttcaa
    37321 tcaatgaagg aacggcgttt aaagattata caacgatcat agctaaacag atttcttaga
    37381 atgattacac ttgtaaacgt tgtgggtatt tagtataatt aaggtagtaa atgaagggtt
    37441 agctgcctga attttgcaag acttagctag tcgaaatcta ttgttggact gaaaattgta
    37501 ggtgtggttg caaacatgct ggactaagaa agatgataga tgatgaacgt tcaattttaa
    37561 tacaggcatg ctaggactga ttggatggtt ttggcaagct gattgtgtag aaatcaaaga
    37621 acacgtctgt tgtggacgtg ttttttttgt tataattcaa aagaggtgat ttaatggaca
    37681 aagcagagtt tacaaatttt tattggaagt attatctaca tttagaaaat gagtttatta
    37741 ataccacaga ttttgtgatg ctcgatgaga ataatttcaa aacattctct attgaatatc
    37801 aaaaactact actagcgatt ggttcggagt gtgagattat tttcaaagaa ctttgcggat
    37861 ttgatagcag tagcaataaa agcataactg attttaaagc tgttattaaa tctagcgaat
    37921 taatgtgttt ggataatggt gttagggtta tgaattcttt aacattgact tcactaaaac
    37981 cttttggaga tgggtggcct gaagatacac cagattggtg gaaaatatat aacagagtaa
    38041 aacatggtcg ttcttcaaat tataaggaag caaatttgga aaatgtgttg tatgctttag
    38101 caagtctata tttattagag gaatatttgc ataagaaagt aatactagaa ggtgaagtag
    38161 actttataag tccagagtca aatctattta cgttatcttg ggaaagaaaa cattcgtcga
    38221 tgcaaaaagt gacgtttgaa aaagtggatt caaattatgt agctccactc attgatttta
    38281 aagaacaaga agaaatttaa aaacccccac ggcttattga agtttttgta tgccatattg
    38341 tatgccattt ggtttaaatc gcttgaaaaa tagtgataga taactctaat tcatttagtc
    38401 ataaacgctg ttttgataac ctttatagtt ctttgatatg ggtttctcat tcatggcgga
    38461 agaagaagaa tagaacaaaa gaatgaatta ataagatata aaaaaaggga ttgtgacaaa
    38521 cgtcttgtca caatcccttt ttccaaataa acgatgttca atcagctgcc cctcggcatt
    38581 cgctcgaaaa acggcgaaat atgaagaact attttgccat ttgtttctct aataatcagg
    38641 tcaaaacgtt gacttcacag tctcttcctt aaacggtgtt ctcctgccaa ctcctcggtc
    38701 acaagtcaca atattcaaca aacatgagaa gctgtttttt gaaattgttc cttgtgactc
    38761 ggagctgaac ggcaggctca cgacctcttt cttaaacggt gttcaaaagc ttgcatctgc
    38821 ggtaataagt tcaaccaaac gaaaattatg aggagctatt tttgtttggc tgttcttatt
    38881 acttgatgca ggacagcttt ttcacaacct cttttcgttt agcactaaat ttccttaaaa
    38941 agtagaaaag ctttcgaagc ctcgtttgtt tcttttactg tataataaaa gaaaagagta
    39001 acaatcgcta aaagatataa acaagagaaa ggaaatacaa gatgattggt ctgatttatt
    39061 ttgtggtgat cgttctggcg aacacagttg gcgctatttc cgggatgggt ggaggcgtgt
    39121 tgatcaaacc gattcttgat cttatcggcg cccattctgt tgcagggatt tctttttact
    39181 caacagttgc ggtattcacg atgtccattg tttcgactgt gcgacaagta tcaagcggga
    39241 aatcactgaa ttggcagatt gtcggttggg tatctagtgg agctgttgtt ggaggagtag
    39301 tcggcaacat tgtattcgaa gtttttttac agttatttga aaacgagaag catgtgcagc
    39361 tgatccaaat ttttttgacg gtattgacct tggtttttgc gttcttctac accaagcatc
    39421 atcagccaaa atttcatttg acgtcatgga cttggtacct tatatgtggg ggggttctgg
    39481 gctttttagc tagtttttta ggtattggtg gtggaccagt caatgtttct ttgttgatgc
    39541 tgatgtttgc attgccaata aaagaagcaa cactatattc tctatctacg attttctttt
    39601 ctcaactggc aaaattggta acgattgctt taacaagtag ctttatgcgc tttgatttat
    39661 ctatgttgtt ttatgttatc cccgctgctg ttattggagg tttgtgggga gcaagattta
    39721 gcagggtttt gtctccaaaa aaagtgacct ttatttttca agtaattgtc ctcgtggttc
    39781 ttttgatcaa tctttacaat gctttcgtca tcttacaaac attaggagaa tctagactaa
    39841 cgcaagtcaa aatcactgaa acatattgtt ctaaatgaaa aaaggagtat actgtgataa
    39901 aaaaattcat ttaaaaaaat aaaaattggc tggtgatttg gatgttgcgg gaaatgcgtt
    39961 taggagatgc agaagcacta cgagaaatca atgcggaaca attaggatat gatgtaccat
    40021 taaccgttac ggtgagacaa atgaagaaac tgttgaagga gccagaaaaa aattttttct
    40081 tggtctatga agatcctact tctaaaaaag cagctggcta tgtacaagcg gagtcctatg
    40141 aatcgatttt cagcgatccg atgttcaata ttatggcact tgctgtgtct aaacatgctg
    40201 aaaaaagagg aatcggaaag gccttgatga ctggcgtaga agaagcgaaa agacgaggaa
    40261 tatcagcaat aagacttaat tctgcagaat acagagtaga agcacaccga ttttatgaac
    40321 gcatcggtta tcattccgat aaaatgcaaa aaagattttt gaaaatcctg taaattttta
    40381 tcaaaaaata cctggtcatc aagccgatac ttgatgatca ggtatttttt ttgactaaga
    40441 aagtaattgc atcaagaaac ctgagatgat caaaacgatg gcaccaccaa gccgattgcc
    40501 catttgagca aaagcaataa gttccatccg attagctgca gataagacag ctacatttcc
    40561 tgtaccaccc atcgagttgt tgcataagcc agcagtaata gttgattcga ttggatataa
    40621 accaaacaaa cgaccgacaa atcctgaaac tactgaaatc gcgataacac ttgtcaaaca
    40681 taagacaaca aattgccatg tcaaagcaga agccaataca tttagattca ataacgcaat
    40741 accgataccg gcaagaacag ctgctgtcaa gtttttgaca atcaagttgt tgaacatgat
    40801 agctgcatct tcgtaatatt ctggtaatag gtttgcgatt ttacagataa caacgataat
    40861 gatcatgaat gcgtaagcat ggactttagg aacaaaatag ttacagattt gtcctaagat
    40921 gaagaaagtc aatgatacca tcaaaccgac acctaattgt ggaatggaag gttttacatt
    40981 tctaggtttt ccatcgccaa ggtcgccttt ttccattaat ttaccattac cgttgaattt
    41041 tggcattgat tgtcccgcac gagcaactaa cgctgcacca atgatagcta ggacatttgt
    41101 cattgctgtc gcaggaatca ggcgggaaat gatagaagaa gcgtccgtac ctaaaacatt
    41161 tgcataaatc gttgataaag gtacagctcc ggctccaaca ccaccagcca ttgcgggcaa
    41221 tgagatatat aaaacggaat ttgcaaaacc atttccgata agcataccta cgagtcctac
    41281 ggcaaaaaag gagacgacca ttgaaataag tgcaacggga ataaaacgaa cagaagcttt
    41341 catcaataga ttacggttca taccaaggat gctaccagta atcaaggcag caatataaaa
    41401 gtctaaaaag cccatattgc tgacaaagtt ttctgtggat tttactacat actcaggtaa
    41461 gatcccaaat gtagcaatcg cggcagaggc aaagatcgca aaaacggagc caccacctaa
    41521 ataacttttg acgataggga tttttgttcc gataaaatga aataaattac cgaaaatgac
    41581 caaaacagcg attgggccaa tcatattcgt cggtaatttt cctaaagcca ttgcaatgat
    41641 caggacaagg accatgatca aataaagggg caaacttacg ccggtaattt ttgttgacca
    41701 aaacccttct tttttctttt cctcaactgc agttgcggtt gttgtttttt gtgccatttt
    41761 tacagatcct ttcttattct gtatcgtatg aaaaaagcca aagagaagcg gcaaaagagc
    41821 agtagttggc tggctgctgt tttgccgcag tcgctttttt ctttttagac gtcatacaaa
    41881 gtttctgtat gttcttttac tataacaatc ttaatcttct aaagatttat attcaggaac
    41941 ccatttagca gattcaacag cttctttgat atccgtgatt tcttcacgat tcaatttttg
    42001 tgcaacaact gattttgcga cagtttcagc aatcgtttga gagaattcag tgatttttgc
    42061 tactggaggc aagatagctg ctcctggttt tgttacatca acgattccgc ctaatgctcg
    42121 actagcttga gaaatgattt cagcatttac tcgtgtagct gttgaagcaa tcaaaccaag
    42181 ccctaaacct gggtacatca acgcattatt tgcttgaccg atttggtaag ttacaccgtt
    42241 atattccaca tcagcagcag ggatacctgt tccaactaaa gcttttccgt ccgtccattc
    42301 aatcaaatct tttgcttttg cttctgccaa ttttgttgga ttagacaaag gcatgatgat
    42361 tggacgtggg gtatgagccg ccatttcttt cacgatttct tcagtgaatg ctccaggttg
    42421 ggtagaagta ccgatcatga tcgttggatg gattgctttt acaactgctt ctaagtttgt
    42481 caattcatca gcattagtga attctgagcg tttacgagcg aatgggattt gaccaggagt
    42541 caatcctttt gtatcttcaa acaataaacc ctgtttatct acttgataga aatgttggcg
    42601 tgcttcttct tcaggtacac cttgacggat catttcatct aaaaggatgt ttgcgatacc
    42661 tacaccagca gtaccagcac caaatgtcaa gatcgtttga tctttcaatt gctcacctga
    42721 tatattcaat ccacctaata caccagctag tacaacgatt cctgtgcctt ggatatcatc
    42781 attgaaagta gtgattttat cttcgtattt ttctaagatc gttgcagcat ttcctcgtcc
    42841 aaaatcttcc caatgtaata acaattctgg gaataattca gtagctgatt gaacgaattg
    42901 atcaatgaat tcgtagtaag tttcgccttc tacacgagca tgacgattcc ctaagtataa
    42961 tggattattc aataattctt cgttattagt accagcgtcg attgatacag gcaagacttg
    43021 tgcaggattg ataccagccg cagcagtgta gaccatcaat ttaccgatag cgatgtcaac
    43081 accgttcaca ccccagtcac ccatacctaa gattccttct gcatctgtca caacgatcaa
    43141 acgaatgtcg cgtccatctg ctgcgttttt caaacttgct ttgatatttt ctggttcgtc
    43201 gattgaaaga aatgcagcat cttgtggttt caagaaaatt tcgttgtatt gttcgattga
    43261 atccgcaacg acaggatcat aaacgacagg catgaattca actaaatgtt cgcccatcaa
    43321 tttataaaac aatgtccggt tcgtattgaa tagattcatt aagaagatac gtttttccaa
    43381 atcggtctgt ttgcttaagt attgaccgta agcttggaca gattgttgtt ccaatgtttg
    43441 gacagtactt ggaagcatac cagtgattcc gtattttgcc cgttcttctt ttgtaaaagc
    43501 tgttccttta tttagaaaag gattatttaa taagtttagc cctgtaagca tgaatgattc
    43561 ctcctaagtt ttaatacaaa cgaagtatag gagtcagatg aggatatagt caaaaagagc
    43621 aggtataata aattttattt atatgagtaa tagagtcaaa agaaatcaaa atagcggtat
    43681 ttgttctttt tatatcaaca atccttgctt gattactatg cgtatctctt atatgctaaa
    43741 gaaagaaaag tagaagaata aaggatatgt tagatagata aatagaatct ctgaagaata
    43801 aatcacgtga tcgtgacgat aaaatacact tacgtcaggt gataaaaaat acataagtag
    43861 aaaactaaga ggaggaacag aaaatgaaag aagttcaatt gatcagaaaa agcgaactat
    43921 cagaaggtgg ttgcaatgca tgcggcgtag tagaagcaac aagctataca ttaaagcttg
    43981 gtgccaacaa agcgataatc tctgagttga cagtaggcgg tcttgtggac agtctggcgc
    44041 ttgctgaagg ttttattgga gaagatattt atgagatgtt ttcagaaatc cgtcagttaa
    44101 aaaaagggga aaactgcata gaggttcatc atgagagccc gaatgtgaga ttcaaacgtg
    44161 gtgataatga gatgatcttc aataatcatg tgtccgatca caccgagcta tatggaatcg
    44221 tgaatcaaat actaactgag ctttttggat tgggacctta tgcgttcaag gaagaaaacg
    44281 gtaatccaaa attaaacgaa gaatggcaag aaacgattga aatacaaaga aacaacccgc
    44341 acttatttca ataggcatcc acagtatttc gtaaaaggga ctttgacacg acttttgtca
    44401 aagtcccatc gttttttatc tatttgtgtt ctaaacattt ctttcagagt agtaacaact
    44461 ggaatgactg aaatgtaaac agattatttg cctgtatcaa tacggaagag taatataaag
    44521 tgtgtaaacg ctatcatatt attcattcaa ttttttatag agggaaggca ttgaaatgga
    44581 aaaaacgtat caagcaggta caaatgaagg aatagtggat tttatcaata tggaagattt
    44641 agaaatagcc gcttcacaag tgattccagc tggtggttat ggttacatca gcagtggtgc
    44701 tggcgactta tttacttatc aagaaaatga acgggcattc aatcatcagc tgattattcc
    44761 tcatgtatta aaagatgtag aattacccga tacaactaca cattttgaca aagaaacgct
    44821 gactgcacca atcatcatgg caccagttgc tgctcatggc ttagctcatg tgaaggcgga
    44881 gaaagcttct gcaaaaggtg tagcagattt tgggacgatc tatacagcaa gttcttacgc
    44941 ttcttgtaca ttagaagaga taagagaagc aggcggggag aaagcaccgc aatggtttca
    45001 attttatatg agcaaagatg atgggatcaa tttggatatt cttgaagtgg ccaagcgtaa
    45061 tggagcaaaa gcaatcgtat tgacagcgga tgcaacagtt ggcggaaacc gtgaaacaga
    45121 ccgcagaaat gggtttacct tcccactgcc aatgccgatc gttcaggctt atcaatcagg
    45181 agtaggccaa acgatggatg ctgtgtacaa atcttccaaa cagaagctta gtccaaaaga
    45241 tgtagaattt attgctgctc attctgattt gccagtctat gtgaaaggtg tccagtcaga
    45301 agaagatgtc tatcgttcat tagaatctgg tgctggcgga atctgggtat ctaatcatgg
    45361 tggccgtcaa ctagatggtg gtccagcagc gtttgattcg ttgcaatatg tggcagaagc
    45421 agtagataaa cgtgtaccaa tcgtgtttga cagcggtgta cgacgcggac agcatgtttt
    45481 caaagcaatc gcatcaggtg cagatcttgt tgctattggc agacccgtta tttatggatt
    45541 gtctttagga ggaagtacag gagtccatca agtgtttgat ttctttaaaa cagaattgga
    45601 aatggtcatg caattagctg gaacacaaac agtagaagat atcaaaaaaa taaaattgcg
    45661 tgagaatcgt tttatttaag aaacaaatga cgaaaaaaat aggagtgcgg cagatgatgc
    45721 cgtactccta tttttatagt tcaaggatgt cactaataga ataatttgaa acgaaaaaat
    45781 aaaattgaaa tattttttca tacttaataa aaaaggaaga atattcatgt aaacgatttt
    45841 attgtttttt tctcttttat acaaaaaggg tcataatttc aagtaagcgg atgaattcat
    45901 gaggattttt tgcatactgt ctctactata cttaggtcac taagaaaaag gagtgattta
    45961 ttatgaaaaa gaacatgatt gggacattat tactttcaac acttcttcta ggcggcttgg
    46021 caacaccagc ttttgctgag ggtcaagcga cttcaaaagg agatattacc tttactgaac
    46081 caacaaatac cgtggagcct cttaacccta ctgatccttc aaaaccagta gagccagcag
    46141 atccggaaaa tccagcaact ggccagacag gtcctttaac actggatgta gttcccgaat
    46201 tgccatttgg tacacacgag attgaaagcg gaacaaaaac gtatcaagta gacgcttcaa
    46261 aaaacgatac accttatctc caagtatcag atcgtcgagg tgtaggtgca gatggccaag
    46321 cacaagggtg gaacgtgaca gtttcggttt cagattttgt aaacggttca caagttttgc
    46381 aaggcgctga attagatttt ggaacatcca ctgttaaaag tacgtcagat aacgaatcca
    46441 ctggaccaac tagtcaaact gtaactgggt tgagtaaagc aagtgcagcg acaccaatat
    46501 ttacagcagc aaaagatcaa ggtctgggaa catggctttc tgtttatgat ccagcaaata
    46561 tcacactgaa agtgccgaaa gcagcagctg gaacattcac ggctgatttg acttggaacc
    46621 tcgtggctgg cccagtagca tagagtatga aataaattca acaaactgcg gtgaaaatac
    46681 tataggtgaa ggatttttta ccgcagtttt tgttgaaagg atgtggtgga caatgaatca
    46741 aagtaaacga ctgtttgttt cgtttttttc tattttaagt ctatttttca tttttccgtc
    46801 aatcagccaa gcaaaggatt cagcaggaga ctttggaatc aaaccggtat ttccagagaa
    46861 ccaaatagat aaagcaatcg gttattttga tttattagtg gcaccggaac aaaatcagac
    46921 actagaagta attatcagca attcttcaga tgaagaacga acatttgagg tctctgtcaa
    46981 tccggcggta acgagtgatg gtggaacgat cgattatagt caaaaaaacc caacgttaga
    47041 tgagacattg ccgtttgatg tccgtgacgt tttgctcatt gcgaaaaagg aaatcaatgt
    47101 atcagcacat gcagaaacaa ctgtacctat agaagtgaaa atcccagcaa aaagctttaa
    47161 gggacgtgta ttagcgggta ttcatgtttc acctaaagaa gaagctgaaa cagaaaatgc
    47221 tacagaagga gcacaaatca aaaatcgtat tgcttataat ctcgcagtcg ttttacaaga
    47281 aagtcaagag acgatagaac cggatctgaa acttttatca ggagatttgg acgaggtcaa
    47341 cgcaaagcca actgttcagc ttcgtttcca aaatcctcag cctaggatta tcagcaattt
    47401 gatatttacg agcaagatct tttatgaaaa tcagctttat attgaaaata cgtctaatgc
    47461 atttttagtt gcaccaaatt cgaattttca cttgaatctt gatttagctg gtgataaagc
    47521 aaaagccggc gattaccgcg cagaaatcat agcaaaatca ggcgacagta atgaatggcg
    47581 atttacacaa aactttacga tcaaaaaaga aaaagcacaa aaagtaaatg aaaattccgt
    47641 ttttgcagta caagaacaat ctttcccatg gctttatgca ggattggttg ctgcagttct
    47701 agtgttatgg ttgattttgc tgtttttgtg ggtccacaag aaaaagaaaa aaggagaaac
    47761 aacatgatga ggtgatttcg ttgaaaacat cgatcttatt gggagggatt attgcaagtt
    47821 tgctgttctt cagctggcaa gagccagtcc aagcagatac caaaagttca ggtacgatta
    47881 cattttatga tctaagtcca attccgcatc caagtggttc agtcaatggc gcatcaaaac
    47941 agcagacaca gctaccgatt tataaagaat ctaatcaaca tggcgtattc ccggagacga
    48001 atgaacaaaa gatccgtttt ctttatttga tcattggtat agaattatgg cttcttgcgt
    48061 ggttgttgtt atggagaaga aaggaaaagg aggatgaaca tgttgctaca aaataaattt
    48121 tcattttttc gctccttctt ttttacttcg ctttttgttt taagtatatt tatcttttca
    48181 ccttcggcag aagctgttgg agcaacgcct cctgccattt cttatgatcc atacacgtat
    48241 gaaaatatcg tacctccaaa tggtggacgt agtgcagtca atggcgggaa gcttgtccaa
    48301 ctaactgggg ctaaccaatt gcctaaattg actgctactt atttgaacga tggttcaaat
    48361 gatccttgga aaggtggcac ggtccgtttt cattgggaaa gccatgtgaa actaacaaat
    48421 gtacttgatt tggtgaatat cactgcacaa ggatttgcat ttgtggcgat catcaatttg
    48481 ccggaacatg tatcaagcag tgatgtatta aaagcaattg actggaacaa cgcctacttg
    48541 tatattgccg gtgcccccat caaggttact agcggaagtt tattatcagc aggaagccat
    48601 accttgcgtt ttgggatggg gtcgtgggat acaaatactc tattgacaga tattattgct
    48661 attattacgc gaggcgaatt caacgtggac gatatcccgc ttcaatttga tgttacagct
    48721 aatgtcgcga agatgacaga aaacggagat aaatatgata cgagtccaaa caaaattttg
    48781 accaagggta aattacaacc ttctatgtct aaaaaggccg ttttttctgt tgatttttat
    48841 gattcgaata atattatcca agatcgtatg ttcaattcga ttttagctcc agctgcaggt
    48901 agattttatc ctaaattaac tggcggaaac ttgaatccag gagcatatgc attttctgca
    48961 agtgcagaga taaatacgtg gaatagttac atctcaccaa gtgattcaac aggaaaatat
    49021 aatacatttg ctgataccac agaatacgtg gatggaaata accagaacct tccaggctct
    49081 accaatagtc ggacattgac gatggggctg actgaaggac gttttgatca gttgccattt
    49141 agtcgctttg atcgcgtagt caactatttt acaggaaaaa acgttacaca aggagcaata
    49201 ctgactcata ctccagcaag cacaagtgga ttgaatcaga cagccaatat cgtgtacagt
    49261 gggaaagatg cgcaaggcgg attgctttct cctgttgctt taaaggtatt ggagcagtac
    49321 aagctagacg gaacggtttt accaacaaac ttaacagccg atagtcagtg gggaaagctc
    49381 ctttcttctg catcgtacca agtcacggcc aattggtcag caactgaact aaaaaagggt
    49441 tcgatccatt acaggcttta ttcgaaagga acccaaaaat tagcgacagg atggacagat
    49501 caacttttcc aaacgatcca atcaaataac gggggtgtaa atacagctac ttctacacta
    49561 cctgcattgg cttcagggca atattatttt gattatcgct tggtggacga tgtacttact
    49621 aacatgtatc cgtcttttgc gtacaaatgg cagtctgaac aagctggaat caccactctt
    49681 cctcaaataa cagtggctaa ttttccatct gtgagtgcag atagtcagct aaaaaacctt
    49741 agcagacaac ctgagacagg agatcccctg tctgctctat caggagatac gattcaagaa
    49801 aatgtgacat tcacgttaac aaaatctggg gatgcgataa ccgacaaaaa aatcacgatc
    49861 tcacttcctg aaaatactac ttatatcaat ggttccttaa aattaaatgg tacaactatc
    49921 gcagataccg gcattcaaca aggagtttct gtcccagcag atctattgag caaaatagga
    49981 gataccattc atcttactta caactatcaa ttaaatactg tagatacttc tttacaatcc
    50041 gtcagcatac tgacaaaggc agctgtactt tccagcaata ttacattagc agatggtgct
    50101 aagcttccta acccagttgt ccaaacatct gctaaaacaa ttcttgtccc caaacaagaa
    50161 ttaacattag ttaatgtacc agatgatttt acatttggta acgatctccc caaaccgttg
    50221 aagacaagtt attatgaatc aaaaggcgat ttttcttttg atgtgcggga tactcggctt
    50281 ccaagcacgt ctccttggca actgacaggt acattgactt ctttatttaa gaatgatcaa
    50341 ggtcaagaat taagcggaac aaaattatac ttcaatcatt ctggatcaaa gcaattgatt
    50401 cagcaaggtc aaaacacgtt gatttatgag agtgatggaa cagctaaagg agaggttctc
    50461 gttgactttc ccgataccga tggtttactc ttagaggtaa atagcagtac gaatgctcaa
    50521 cctggcgcaa cgtatcaagg catggtcaca tggaaactga cagctgggcc aaccagctaa
    50581 gtgattagaa tttgtatgga tctgtgataa ctgtcacaga tcctcttttt caaggatgag
    50641 aaggaaactt ctgctgttaa aatcagaaat gcttgaagga gtggacttgg aacttttcag
    50701 tttgcttgaa aaaaatgaac aacggcaaat caaacttttc caacttttat tagaggaaaa
    50761 aggagaggtt tccgttaata acgtacttac ccgcttatca gttgatcggg ctaccttgaa
    50821 agaagatctg ttttatttac aagctaactt ggaaaatatc aaacaattgg aaattgttat
    50881 ccaagaaggg aatattttat taatcagaca tggaaatata gcagcagtcg atgtttatta
    50941 tcattgttac ttgcgctatt ctacaaaata tcagatactt ctttatctgt tggaaaatgg
    51001 ctcatttgat cggcagaaac ttgtcatgga acttaatatc agttcggcta ctttgtctcg
    51061 cagagtgaag gaattaaatg attctttaaa tgagtttcat ctgaaaataa aaagcgggcg
    51121 gctgaccggt ccagaaagtc aaattcgtta tttttatttc caattatttt ggtttggacg
    51181 tccctatctt gaaaacaaaa aagaatacag tgatttatca ggaaacactt ttttagatct
    51241 gctgcaaaaa gagtttagtt ttgctattac agaagaagga cgattgaaat ttgaaatatg
    51301 gctttccatt atgaagaagc gaatgcgctg tacgaaaaaa tccaaaccag attatagcaa
    51361 tcttcctgtt ggattgtttc aaacgacaca atttttattg gacctccata catttttgac
    51421 ccgttacttc tttcaatatg cctttccttg gaatcaaaat gaaacgttgg ttttttatct
    51481 tttcatgatc agtaacttta cattagatac acataactcg catgtccagg agtttttgat
    51541 aagcgaaaaa tacaaagacg acgtagtagc tcaattgaat cgaacgttta aacaatcgat
    51601 agaagaatat ttctcttttt atgtttttcc agaagagatt tcgcaaaaga ttgcgttgac
    51661 agtgatgcaa aatcacgctc attttgccta ttttagagga tggatgaata tttttggcca
    51721 agaaggatta aaacagcggt taactgaagt agaagataaa caattcctgg ttttatgtga
    51781 aagattggtc agacaaacat ttgctattgt tgattttact gaagtagacg aggaaaatgc
    51841 ccgctttgaa ttatttgctc gctatgcatc tattttacgg acgctgatca agcagttaga
    51901 attacgtctg caaattgctt atgatcttcc ttatgaaagg ctaatggcgg atatcgtgaa
    51961 agaaatcatc caggaacaat tgctgaatac gatcaaatat gatttagtcg aatacgagaa
    52021 agaaaagcag tatgatatca ttttgactag ccaattgaaa gagtacccgt cacagaagtc
    52081 cgctaaagtt tttgtattca ctagcaacga atataattat gatttcccct atttgaacca
    52141 atttttaaaa gaatgttatt tagaaaaatt gaatttaagg atgaataaaa catgaaaatc
    52201 gtgatcattg gtgcttccca tgcaggcatc acagctgccc taaatctaag aaaacttcaa
    52261 ccgaaagcag aagttttact gatcgatgaa gatcataaag atggactagg ctatgtttca
    52321 aatggaatca acctttattt aaaaggaaag atacgtagtt tagctgaagt tgcccataac
    52381 atgcggactc ttcaagaaag tggggcaaaa ctgatcaccg aatggagagt aactgaactt
    52441 gatccagaca aacatcagct catcctcgca tccaaagaag gaaaaaacga gaccataacc
    52501 tatgataaat taatcgtagc gacaggttcc tctcctgtca ccttgtataa acaaattgaa
    52561 gctgaaaatg tctacaccta taaaaatcta gtgcaatcta agcaagtact tgccgcttta
    52621 aaagaagcaa aagaagtagt gatcttcggt gctggttaca ttggattgga attagcagat
    52681 gctttgagaa ataaaggata cattattcat ctagttgatt atatgccgaa tgttttatca
    52741 agatatttcg ataaggatat gatcaacagt tttcaaaatc agctgcaaac taagcaaata
    52801 aatttttatc caaatgaatt cttgatcgat tggaaaaaat cagaagagaa agtagtatcc
    52861 gtacaacttc tgtctcaaac aataaaggca gatatggtca ttttttctgc ccaaactcgt
    52921 cctaatacga cattgttaaa agaaaaagtg gctttgtatg aggatgagac tgtgatagtc
    52981 aatgaatatc tgcagacaag tgatccggac atctatgcga ttggagatat cgtcccagtc
    53041 agttttgaca aaaataaacg gcatctcttt ttacctttag ttactcgagc tgtacatatg
    53101 gcaagagcag tagcgctaac tttgagtggt cagccaaccg cttacgacct cagacaaaag
    53161 ataacagcag cagtcattat agactacttt ttaggaactg tagggctgac agaagatgaa
    53221 gcgccattct tggaacaaaa taccggttcg tgttcaggag aatttgatct atttccacaa
    53281 tacgacgaag aaaacaaaac agtaaatgca aagctgatct accatccgga tacattagaa
    53341 ataattggcg gacagctgat aagccaagaa ttcttattat cagatttgaa cctgcttgcg
    53401 gatatcgtga aacacaaaac tacgattcca cagctagcag ttgaggattt tggatttctg
    53461 tctgaataca cctctcgttt tcactacctc aatgagttag cttttaaagt actagctaag
    53521 agagcaaata gcaatagagt agataaaaga ctgtgagaaa tatcacggtc ttttattgtg
    53581 tggggatata ataaatatta atcaatcgag aataaaaaat tcatataatg aaatagcgga
    53641 agaatttttt gagcataata ttcgccaaaa atttatcaag tgataaaatt gttgtataaa
    53701 atgattattt caggaggagg agttaaatgt ttttagcatt aaatgaaatt atgcattcaa
    53761 agttacgtta tgcgttagtt gcaggggtga tgtttttgat cgcctacctg gtattttttt
    53821 tgactgggtt agcttatggc ttagctcaag ataatcgaac agcagtcgac aagtgggagg
    53881 cagattcgat tgtgctttcg aaagatgcaa attcaaatct agggatgtcc atgattacta
    53941 agaagatagc agaagaagtc gaaggtggga aagtggcgta tcttgcccaa acacctggag
    54001 tcgtgactag taaagacagt acagaagaag gaaaaatcaa tgttagcttc ttcggtatcg
    54061 ataaaaatca attcatcatg cccaatcttg ttgaaggaaa agcttttgat aacgatgatg
    54121 aggcagtagg cgatattagt ttgaaagaag aatatggtct agccatagga gatacagtta
    54181 agttatctgg tagtgacaag acgtttaaac taactggctt tacggatcat gccaaattca
    54241 atgtctcacc agttctctat acaaccatca atgcttacca agaaatccgc ttcgaaaaag
    54301 aagatacaag tgaaaatgca cggattaacg caatagttgt cagaggtaaa atcagtaatt
    54361 tacctgaaga tttagaacag atcaaaattt ctaaattcat caatgaatta cctggatata
    54421 atgcgcaagt attgactttt ggatttatga tcggattttt gatcgttatt gcggctattg
    54481 tgatcgggat tttcatttat gtactgacga tgcaaaagat taatatcttt ggtgtaatga
    54541 aagcacaagg gatcacagga ggatttattg cgcgttctgt agtggcacaa acattcattt
    54601 tatcatttgt tggtattctt cttggtctat taggaacagt gggaacatcc cttgttctac
    54661 ctgatgcggt tccattccaa agcaattggc tgttttttgg cgtcattagc ttgttgatgt
    54721 tagtagtagc tgtgttaggc gcactatttt ctgttcggac aatcgtaaaa atcgatccgt
    54781 tgaaggcaat tggataagaa ggaggaagaa catgaaagca atagaattta aagaagtaga
    54841 aaaaagtttc caagatggcg accaagtagt taaagcattg aaagaaacaa ccatgagtat
    54901 cgataaaggg gaatttgttg caatcatcgg tccttctggt tcaggtaaaa gtactttttt
    54961 gactttggca ggcggattgc agacgcctag cagtggctct gtatttatca atgatcaaga
    55021 attcagtaat caaaaagaaa gcgaacgcgt taaactacgt tttaaagaaa ttggctttat
    55081 tttgcaagct tccaatctgg ttccttttct gacagtaaaa aagcagttat tattagtaga
    55141 taagattaaa catgaacatc gtcaaaaaga agcaaacgaa ttatttgagc agcttggcgt
    55201 ggataagttg atcaacaagt atccagaaga actatctggt ggagaacggc aaagggtcgc
    55261 aatcgctcgt gcattgtaca atgatccgtc cattattcta gcagatgaac caactgctag
    55321 tttggattca gaaaaggcac gagaagtagt cgatatcttg gcaaaagaat caaaagacaa
    55381 aaataaagca acgatcatgg ttactcacga tacacggctg attgacaaat gcgatagaat
    55441 atttatgatg gaagatggtg tattgaaaga aaaagaataa ccaaaaagca ggtggaaaaa
    55501 tggtccatcg atacaacaaa gatacacagc aaaaaatttt gaaagaagcg actgacttgt
    55561 ttatgtccaa gggatatctc ggcacttcaa caagagaaat cgcacaaaaa gttgggatca
    55621 cccagcccaa tctctatcat tatttcggtg ataaagaaaa actatatacg gcagttttag
    55681 aaaaccactt aaaagatgtt ggaaaagctt tgagagaaat cgttcaaaca agcgaaacgg
    55741 gatttcaagt aaccttgaca aaaatggcgc agtttttgat tgagacacat ctggtcgatt
    55801 tgtttctgat gcttcacgat cttgaaagca atctttcaaa ggaaacaaga gatcatcttt
    55861 tctttctatg gaagaaaaat tatcgtgaac cttttgaaga aatcttttca gcaaaccaat
    55921 ctgtgctaag aaatgggatt tcaaaagaaa tcgcagcaag gcattttttc ttagtgttag
    55981 caccttacat cactcggtcg aaaagacctg tggaagaacc gctaaatgtg gcgcaattga
    56041 tcgatttata tttgaatggt gtattaggag aagcgtaaag ctgttatata gggagaaaat
    56101 agttaggtga agaagcaaga tatgacgaag atcgttatat cttgcttctt tatataggta
    56161 gtttttcata aagacaaatt tgttattctc tcatgattat cagggtatat ttttatttat
    56221 tatgtcggtg ttccaggaag tgttttaatt taataacgaa gaaattaatt gtttgtagaa
    56281 tgaaggaaac tatttattgg gtagatgaat caccacgaat agtcaaaagg agatttcagg
    56341 atatgccaaa aatgaaaaaa atcattttag cagtaatgtt attttctacg gttatatctt
    56401 ttacagcccc ttttttgctt acttaagctg attttaagtt ttggccctta gtctggatct
    56461 acgaggtgag agtcaagaat gaaaaaaata attggagctt ttgtatttgc aatcattatc
    56521 attattatct gttttcaaat agatgttttt ggtcaaaaaa agatagttgg acaaacggtc
    56581 agcagtacga acagtacggt tacaaagaca aaggaatcat ttgatgatac agaacaagag
    56641 acattaatca aaatcggaaa aaatgaccgt acactatata cagatgactc gctaactacc
    56701 ccacttgcaa ctataaacgg cggagagctg gcggagtttc tttctgaaac aaaaaatgct
    56761 tatcagatca agacaaatga tggctatact ggatatttag ccctcgaaga tggaaccaaa
    56821 gtcacaaaga atatacaaac aaaaccggaa gagctatctg atgcagtgat tgtattagat
    56881 cctgggcatg gcggaaatga tactggggca ttaagcaatg atgaacaaac agaagaaaaa
    56941 gatataacat taagtacagc cataaaagta aaaaaggcgc tagaggatgc tggagcaacg
    57001 gtttatttga cccatactac agatgaatta gtacagcttg gagatatatg cgactacagt
    57061 gaagaaaaaa aggcagatgt ctttatcagt ttacacgcag actctacgga atatgcgaat
    57121 gaagcaactg gaatcacgac atattattac tatggacaag aggaaacatt agcacagaca
    57181 attgctgact ccttcactga tctgcctctg gattcaagag gaatctccac tgggaactat
    57241 caagttcttc gagaaaatct tcaaccttct attttaatcg agatgggtta tatgaataat
    57301 gatagtgatt taaaggaatt agtaacagac agttatcagc agcagattgc tgcaagtttg
    57361 acacaagcat tgaccactta ttttcagtaa taaataagcc cagccaaaca aaaatagctc
    57421 ctcatatttt tcgtttggcc gggcttatta tcgcagatgc aagcttttga acaccgttta
    57481 tttttttagt agcttcaaag ctttttctgt atttgcaaag tgaagtttgg catatttttc
    57541 aagcataggc atgccgcctt tctccaatag ttttgccgct acttggtcag atttcgttcc
    57601 agctcctgat ggaagggtga ttccagcttc agctgatgct ttgtgtaact cttccaaaaa
    57661 gctggcacga ctgatgatag aagcagcagc aacagctaaa tgatattgtt ctcctttagt
    57721 aacgaagtac agtttttctt gtaattgatt tttttctaaa cgcgcatatt ttttaaaatt
    57781 tgcttccggc gtaaactgat cgatcaaaat cgcttctggt ttttctggct cgattttttt
    57841 tagcagcaaa tggatcgctt gattgtgcaa agcgactttc atccgaacgg cattgtattt
    57901 tggttggatc tcattgtatt tttctggaga taagacaagc agtttatagg ggatggtttt
    57961 ttttaagatg tcagcaagct ggatgatttg gctatctttt aactcttttg aatctctaac
    58021 accaagttta cgtaattctg caagctgatc acgtttcaca taagcagcac atactgttag
    58081 cggaccgaaa tagctgccat ttccgacctc atcactacct aaaacggata attgactgat
    58141 attttttggc aaagaagagg ctgtttttgc tggcttggct tgtttatcct gtgcctcccc
    58201 ccatttatca gcttctattg ctgcattcgt accttgaaac atcacttttc cggatgtata
    58261 agcggtaatg gtcgtcccgt ctttttttgc agcaaagcta gtataaggaa tctgtttatt
    58321 taacaaataa gagcgatagt atgctttcat ttgactaagt tggtcgtttg ttgctttgat
    58381 aatgacgttg ctcataaaat tctcctcgtt tttatacata aaactatacc gcaactcacg
    58441 acttttcgtt ttctaagaga ttgcgagaca tagcattttt ttaaagttta tcatataata
    58501 gttaagtatg tgaaaaatat ttgtggagaa cggtgaaaga accaacttca tggtacacta
    58561 aataaaactt tcatcaaata ggaggaaatg attcgtatgg cgcacgaaaa aacacgctac
    58621 aaagcggtga ttgccaacca aacatatact attatcggac gggaaaccaa gcatcatatg
    58681 gatatcgtaa cgaagctgat caatgaacag ttagcagaat tgaaacaatt atcaccacaa
    58741 atggataatg aacaagcagc aatcttgatg gctgtcaatg cgctttcgga tcaattgaag
    58801 aaacaagaaa gaatcttgga gctggaagaa gaaacagcag aattaaagaa aaaaatgatc
    58861 aaatttacag agcttgaaaa tcgtgtgaaa cgcattgaag caatcgagaa cgaagctcgg
    58921 gaagtattga aagaaaatgg tcaagcagat cataccatta aaaatcatgt ggaagcacaa
    58981 cagattttaa acgagaaacg aaaaggacaa attaaacaaa aatcttctaa ttaagatcct
    59041 tttatcaaaa taagaaaaat ttaaaaaaag ttagaagaga aaggaacgta gcatgctgag
    59101 tttgctgatt ttatttttat tgctaattgc gtttttttct ggagcacgtc gcgggtttgc
    59161 tttgcaaatc atattcgcga ttggatatgt attgtcattt attgctgccc agcattttta
    59221 caaaccatta gcaagtcatt tggaattata cattccatac ccagctgtca cgccaacatc
    59281 aaagttagca ttttttgatc aggtatttgc ctttcaccta gatgaagctt tttatgcagg
    59341 aactgctttt ctgattattt tgctaattgg ctggctgctt acccgatttg tgggggtttt
    59401 tgtccatgga ttgacgtatg tgccgatctt gagacaggta gactggattg caggaggcat
    59461 cctgtcacta atcatggctt acgttactat atttttgatt ttgcagttac ttgcctttgt
    59521 tccattagat gtggtccaaa atcaattcgg cgagcatagt ttcgctcgct ttatcgttga
    59581 gagaacgcca tttcttacca acaagatgta tgagctttgg gtaacgaata ttttgaatta
    59641 aggaaaatag tgctggaaaa tatttcgttt tttgtacaga gtagattatt taagaaggct
    59701 gcgtagcgta tgtccggcac agctcttttt tcatagtgaa agataaggtg ataaaatgaa
    59761 taaccgaatc cttgaaacat tggaatttga aaaagtcaaa cagatggtca gacaatttgt
    59821 agtgactgca caaggaaaag aagaactggc agaattggta ccagtgagcg aggaacaaac
    59881 gatcacaaac tggcttcaag aaactgagga tggattgaaa gtgcaacgtc tgcgaggcgg
    59941 gatccctata cctaaacttg aaaatatccg tccccatatg aaacggattg agatcggagc
    60001 agacttgaat ggagtggagc ttgcacaagt ttccagagta ttgtctacga caagcgaatt
    60061 gaatcgtttc attgatgatc tttatgacag tgaaatcgaa tttgcacgtt tgtatatgtg
    60121 ggcagatcag ttagtcacga tccctgtttt gagccgccgt ttaaaggaag caatcgatga
    60181 agacggacgc gtgactgatg acgcttctcc tgagttaaag agcataagac agaacattcg
    60241 gcgaagtgaa caagctgttc gtgaacagtt agatgggatc gtccgtggga aaaatgcaaa
    60301 gtatttaagt gatgcgatca tcaccatgcg aaatgaccgc tacgttatcc cagtcaaaca
    60361 agaataccgc ggtgtatttg gcggtgtagt ccacgatcaa agtgcttcag gacagacttt
    60421 atttattgaa ccaaaacaag tggtggattt gaataatcgt ttgcgtcaat accaaatcgc
    60481 tgaacgaaat gagattcaac gtattttaag tgaactttct gctgaacttg ttccccatcg
    60541 tcaagaaatc atccacaatg cttatgtgat tggtaaaatg gatctgatga atgcaaaagc
    60601 acgatttggt aaagaagtaa aagctatcgt gccgggaatc agtgaagaca atcatgtcgt
    60661 cttgaaacaa gcaagacatc cactgatcga tcaggaaaaa gtagtttcta atgacatcac
    60721 aatcggaaaa gactatcaag ccatcgtcat tacaggacct aacacaggtg ggaaaacgat
    60781 cacgttgaag actttaggtc tgttacaact gatggggcaa gcaggattac cgattcctgc
    60841 aggtgaagaa agtcaaatcg gtatttttga ggaagtattt gcggatatag gagacgaaca
    60901 gtcgattgag caaagtctat cgaccttttc ttctcatatg acgaacactg tagatatttt
    60961 atcaaaagtc aatgaaaaaa gtctggtatt atttgacgag ctcggtgcag gaacagatcc
    61021 gcaagaaggt gctgctctag caatcgcaat cttagatgat cttggtaaaa agtctgctta
    61081 tgtgatggca acaacgcatt atcctgaatt gaaagtttat ggatataatc gggcaaatac
    61141 gattaatgcc agcatggagt ttgatgtgga tacattaagt ccaacgtatc gtttgctgat
    61201 tggcgttcct ggacgaagca atgcgtttga aatctctagc cgattaggtc ttgatacaga
    61261 agttattgat gaagcgaagc agttgatgaa tgatgagagc caagatttaa acgaaatgat
    61321 cacagattta gagaatcgcc ggaaaatggc agagaccgaa tatctggaaa tgcgtcattt
    61381 tgtttctgag gcacaagaac ttcacgatga tttgaaagaa gcttacagct atttctttga
    61441 agaacgtgaa aaagaaatgg aaaaagcaaa gaaaaaagca aatgaagtcg tgtcagaggc
    61501 ggaagaaaaa gcagaaaaaa tcattgctga tattcgtaaa atgcaacagc agattgggca
    61561 aggaaatgtg aaagagcatc agttgatcga tgcaaagacc caattagcaa atctacatca
    61621 agaagaaact ttgaagaaaa ataaagtatt gaagaaggcg aaagaacaaa aaacgttgaa
    61681 accgggagac gaagtgttgg ttacgactta cggccaaaga gggacgcttt tacgtaaaaa
    61741 cgggaatcag tggcaagtag aaatcggtat attaaaaatg aatgtgtccg aagacgagct
    61801 gacgcctgtt gctcctcaaa aagagccgac acaacgagtt atccatgctg tacgatctga
    61861 atctagtagt cacgtgccga atcaattgga ccttcgagga aaacgatacg aagaagcgct
    61921 aagtgaggta gatcaatatt tggattctgc cattctagct ggttatcctc aagtgactat
    61981 tgtccacgga aaaggaacag gcgcacttcg caagggaatt actgattatc ttaaaaacca
    62041 tcggagcgtc aaaagctttg agtttgcacc ggcaaaccaa ggcggaaatg gtgcgacaat
    62101 tgttaaattt aagtaaagct tactaaaggt aagcagatgg ttcgctatcc aagtatagaa
    62161 atgctatact agtcatagat tttaaaaatg gaggtctttg atatgtcaca agtaattaca
    62221 gataagacat ttaatgaaga aacagataaa ggacttgtat tgattgattt ttgggcaact
    62281 tggtgtggtc catgtcgtat gcaagcaccg attttggatc agttggaaca agaatatgat
    62341 gaagaagaat tcagaattgc taaaatggat gtggatgaaa atccagaaac tcctcaacaa
    62401 ttcggtatca tgagcattcc aacattaatg ttgaaaaaag atggtcaagt agtagaaaaa
    62461 gctgttggtg ttcattcaaa agaacaacta cgtcaaatga tcgatcaata tttataaaaa
    62521 cttacagcaa aaataagctg agggtgggac tgaatccagt tccgtcctcg gtttttttgc
    62581 ggttgagtta aggttattca aattaatatt ttttgagtat aattacgttg tcaggctgga
    62641 ttgttttttt gacagacatg ctataataac tttaattgaa tatgaagggg agtaccagat
    62701 gaacgaacga atcaaaaaca aattagcttt acttcctgat cagcccggct gttacttgat
    62761 gaaagataaa aatggaacga tcatttatgt cggcaaagcc aaaatattaa aaaatcgtgt
    62821 ccgctcatat tttactggta gccataatac gaaaacggaa cggcttgtta gtgaaatcga
    62881 agactttgaa tacatcgtta cagaatcgaa tatcgaagca ttgctcttag agatcaatct
    62941 gataaagaaa aatgatccta aatacaacat tatgttaaag gatgataaaa cctatccttt
    63001 ccttaagata acgaatgaaa aatatccccg tttggtgatt actcgtaagg tactaaaaga
    63061 caaagcactg tattttggac catatcccga tgtcggtgcg gcgaatgaga caaagaagat
    63121 cctcgatcga ttatttcctc tgagaaaatg caaacctagt cagacgaagg agccttgtct
    63181 ttactatcat ttgggacaat gtctgtgtcc ttattatttc gacgtagatc cgaaagtcta
    63241 tacgaaaatc gttgatgaag tgaaaaactt tttaaacgga ggacacgaaa aaatcgagtc
    63301 agagatccat cagaaaatgg aaaaagctgc tgaaaacatg gagtttgaaa aagctgcaga
    63361 ataccgagac cagatccgtg ccattgagac aatcatgact cgccaaaaaa tgacaaatac
    63421 tgatttactg gatcgagatg tatttggtta tgcgattgat aaaggatgga tgtgtgtcca
    63481 agtgtttttc gtaagacaag gaaagctaat tgaacgagat gtttcaatgt ttcctttcta
    63541 taacgaagca gaagaagatt tcttgactta cctcggtcag ttttatcagg aaaatgagca
    63601 tttcattcct aaagaagtct tgattcctga tacgatcgac aagcccagtg tagaagcttt
    63661 gttagctacg aaagtgctgc aaccaaaacg aggagaaaag aaaaaattag ttgaattggc
    63721 gagtaagaat gcctcagttg ctttgaatga acggtttgat ctgattgcca gaaaacagga
    63781 acggacgatc ggagcagttg aacgtttagg aaacgcgatg aatatcccga ccccaatacg
    63841 tatcgagtct tttgataact ctaatatcat ggggacgaat cctgtggctg cgatggtcgt
    63901 attcattgat ggaaaaccgg caagaaaaga atatcggaaa tataaaataa aaacagtcaa
    63961 cggaccggat gattatgcat caatgagaga agtcatctat cgcagatatt cgcgagtgat
    64021 tcgcgaaggg ttgcctttac ctgatttgat cttgatcgat ggaggaaaag gacaagtaga
    64081 tgtggcaaaa gatgtcttag aaaatcaatt aggaatcgat attcctattg ctggcatggc
    64141 aaaaaacgat aaacataaaa caaatgagtt gctattcggt acagatttgg ctgtagtacc
    64201 gcttgagcga aattcaccag agtttttctt actccagcga atccaagatg aagtccatcg
    64261 attcgcaatc actttccatc ggcagctacg cagtaaaaac agttttgctt cccgattaga
    64321 tgaaattgaa gggttaggac caaaacgaaa aaaaatgctg cttaaagagt tcaaatcgtt
    64381 gaaaaatatc acagcagcca cgacagaaga attacaagaa atcggactgc cgaaaaatgt
    64441 cgcacaaaac gtatttgata aattacatca ggaatgagga aagggcactt tacaaagaaa
    64501 gtaaagtgtc ctatcatttt atgtacaaca aaaagagcgt ttacgttttg ttggtaaata
    64561 ataaatcgct tacgtctggt gtctaaggat atatgtgatt tcttgaagaa ggagtgaaga
    64621 aatgttagaa gtcaaggatc ttgttaaaac ttttgggaac tacacagctg tcgatcatgt
    64681 ctctttccaa atccccgatg gaaaaatcat ggggctaatt ggccaaaacg gggctgggaa
    64741 gacaacgact tttcgtttga tcttggattt tttgacacaa gaccaaggag aagtgttatg
    64801 gaatggccat catcttgggg agaaagatta tgatgtcatc ggttatcttc cggaggaacg
    64861 gggactttat ccgaaagtaa cgattcaaga ccaactgctt tattttgcag aacttagagg
    64921 gaaatcaaga aaagagattg aaccaaaaat cgacttttgg atggaaaaat ttcaggtaaa
    64981 agggaaaaag acggataaag taaaatcttt gtctaaagga aatcagcaaa aagtccagct
    65041 gatcgccacg ttaatccatg aacctaaatt gatcattttg gatgagccat tcagcgggtt
    65101 agatccggta aatgctgaat tgctaaaaga tggaatattg gaattgaaaa aacatggttc
    65161 atgtgtcatt ttttctagcc acaatatgga taatgtagaa aaaatctgcg atcatttgat
    65221 catgttgcga aacggaaaaa tggttttgaa tggaaaagta catgagattc gtgaatcatt
    65281 tggccgtacg aagttattct tggaatctgg tttaagccaa caggaagtag aagaaatcga
    65341 aggcgtgaaa aaagtgatcc ttcatgaaga caatacgtta gagattacct tagaagatcc
    65401 tgaagctggg aaagaaatct ttactcgtgc gactcagttc ggctacattc ctatgtttaa
    65461 ccagcaaccg ccaactttgg aagagatttt caaattgaaa gcaggtgaaa tcgatgcgta
    65521 agttttggat tattaccaaa gatgtctatt taaaaaatgt taagtcgatt tctttcttga
    65581 tcatgatatt agtccctttt atcatgctgg gtatcattta tgtagcagga aactttgctc
    65641 aacaaaatag tgatgtcaat aaaatcggcg tattggctga taatgagcaa atcagtcagc
    65701 aaatgagcca agtcaaaaca gatgattttg agttcaaagc agttgattct gaagaaaaag
    65761 cacaaaaaga gctttcggaa gaaaaaatcg atgcgtattt agtagtctca actgagaatg
    65821 ataagataaa tgggatgctt tatagcgaaa attcattagg acaaagtaca caactactga
    65881 tacaacaaca actgactggc ttgcaatcga tgcttcgagc gagtcaatta ggcatttcac
    65941 cagaagaagt agctagcttg agccaacaag caagtttgac tcgacaaaaa gtcaattttg
    66001 attcaaaagg aaaaatgaca gtcggagaag ataactcgac agtccaatac gtcgtaagtt
    66061 atgtagcaac gattgtcttg ttcattatta ttttgacgta tgcgcagatc attgcacaag
    66121 agatcgcttc tgaaaaaggc acgcggatca tggaagtgat cctgtccagt acgactgcac
    66181 aaaagcattt ttacggaaaa ttaacaggtg ttttacttgt tgcattaacg caaatggcat
    66241 tatacggtat tatttttggt ataggataca gtcaattcaa agatatggaa atggtcaaaa
    66301 atatattaga cggtatctca ttggataact tgattggacc attcttgtgg tattctcttc
    66361 tattcatgat ctttggcatt ttgatttttt ctgttttagc agctttatgt ggctctttgg
    66421 tcaacaaagc agaagataca gcaaaagcaa ttttgccagt gacttatcta tctctaggcg
    66481 gatacatgct tggattgata ctaggagctt cagatccaaa caatatcgtt attcggatca
    66541 cttcgtatat tccattctta tcttcatata ttatgccggt tcgcttagca aatgagacag
    66601 tcggtatggg tggagcattg atttccttgt tggtacttgt agccgtaaca ttcttattga
    66661 tgatcttgtc tgcaaacatg tacaaatcga atgtactcgt ttatagcgaa ggcggattat
    66721 ggagttcatt gaaacaatcg atttcaatta tgaggaatga acgaaaaaaa gcataaaaca
    66781 atcctaaaat acagaaggaa gctggacatc tattgttccc agcttctttt tgtatagacc
    66841 tattttattt attttactat attggatata tattcattga aaatagtgta taacaacttt
    66901 ataatattga gtataccaat ttttggaggc gttttaatgg accgttattt agatttactt
    66961 tcagaaaaat tcccctcaac ggaggatgtc atcacggaaa tcatcaatct cgaagcaatt
    67021 ttgcagcttc caaaaggaac agagttattt ttgagtgata tacatggcga atttcctgct
    67081 tttgatcata ttctgcgtat cggttcagga aatcttaaag aaaagatcaa agaccttttt
    67141 tctgaacaaa tgacggaaac ggatatcagc caattcacta tttttacggc ttatccagaa
    67201 tatgcattaa cgactgattg gtacaaagaa caagataaat cgcagctgat ccatcatttg
    67261 atcgatcttt tacggtttac gacagtcaaa tatacccggt caaaagttcg aaaaggattg
    67321 ccgaaagaat atagctatat cattgaggaa ctcttgtata tcgatgaccg tatcaatgga
    67381 aaaaaagact atgtaaaaaa aatcattgaa caacttgttt tgatgaagga agaagaaaaa
    67441 tttttaacga aacttgcaca gacgatccaa aaatctgtca tcgatcattt gcatatcgtt
    67501 ggagatattt ttgaccgagg aactcaagca gccaaagtga tggatcgaat catggatttt
    67561 tcttctgtag atatccaatg gggaaatcat gatattttgt ggattggtgc gtattgcggc
    67621 tctgaggcat gtttactgac acttttacgg attgcagcac gctataatta tttatttgaa
    67681 ttagagaaag aatatgggtt gaatttacgt ccattgtttt cttttgctca tcaaacttat
    67741 cagaagaatc cagtatttgc gcctaaaaac agtaaaaatc tatccgaaag agagcaagaa
    67801 gaattagaaa aaatccatca ggcactttct atccttcaat tcaaatcaga acatcagtta
    67861 ttggatcgtc gacctgaatt taaaatggac gatcgtaaat tgctggaaaa aatcgactat
    67921 gaagcatcaa cgattgattt agaaggtcag ctctatgagt tgaaaggaac ttgttttcaa
    67981 acgatccagc cagatgatcc aaaaaaattc ttggaagagg aacaaaaagt gattgatagt
    68041 ttgatgtatt cattccagca ctctttgaga atgcaaaaac atatgacgtt tttgatcgaa
    68101 aaagggggaa tgtatctcac gaacaatcag catgtgctgt ttcatggctg tatacctgta
    68161 gacgagaagg gacagctctt agcatttgaa ttagaccaat cttatcgcgg aaaagaactg
    68221 ctgggctttt ttgaaaaaca gataactgaa agcgcaaaag atctgactgc aaaagaagat
    68281 ttagcaaccg atttgatttg gtatgcgtgg agtgggccat tttcgccttt attcggcaag
    68341 agtaaaatgg cgacttttga acgttatttt ctcacagagc ctcatacgca cgtcgagaaa
    68401 agcaatcctt attatcactt gcgagatgaa gagtggttca gtgaaaaaat tttagcagaa
    68461 ttcgacacaa aagaagaagg gtcagcaatc attaatgggc acacgccagt aaaagtaaaa
    68521 aaaggggagt caccgatcaa agcaaatgga aaagtatttg tcattgacgg aggtttatcc
    68581 aaagcttatc aaaaaacgac aggaattgcc ggttattcac tattatgcaa ttcttatggt
    68641 ttccaaatcg tgacacatta tccgtttttg cctattgaac aacaatttgc aaaaaaatcc
    68701 gaccaaacaa atgtgaaaaa agtaatcgaa cagcaactac cacgcaaact caatcgtgat
    68761 acaacaaaag gtatggaact gcagcagcag attacccagc tcaaaaggct gttggactat
    68821 cgaaaggacg attgagaaga attccagtga acattgttcc atagactgga gactgagaca
    68881 aaagtcgtgt cgcagtctct ttttccggat aaacggtgtt cttctgccaa ctcctcggtc
    68941 acaagtcaca ctattcaaca aacatgaaaa gctgtttttt gaaattgctc cttgtgactc
    69001 agagttgaac ggcaggctca cgacctcttg gtataaacgg tgttcaaaag ccagtttctc
    69061 ggtattaagc caaatttatg caaaaatgtg aaaagccatt ttcacaaaat ttttcttaat
    69121 actcgaaact aaacagcttt ttcacaaccc cctcagaaag tctattaaaa ttcattcaca
    69181 aagaaatcga ataagcgctg ttcagatgga tgtacacggt gggtaagttc cggatgccat
    69241 tgaacaccga ggattttatg catatcatct ttgctttgaa ccgcttcaat gagtccatcg
    69301 ttagaaaaag cgatggcttt taataaaggt gaaagatctt tgactgcctg atgatggtaa
    69361 gaattcacaa aatatggatc ggggagaagg ttgcttaaca aactgtctga aacaatcttg
    69421 acttcgtgag tcgtaaattg cggggcagtg ggctgttgtt catgttttac tgaccacttt
    69481 ggatataatg aaagatcttg ataaagtgta ccttccaaaa cgacattcaa tagttggagt
    69541 ccccggcaga ctgcaaaaat tggttttctt tgtttcaatg cttccaagat cagtgcctgt
    69601 tcaaattggt ctcgttgaat atttgtttcc gttagctttg gatgaggatc ttccatgtaa
    69661 agttgtggac tgacatcttg accacctgca agaataagtt tgtcgatttg tccaatcagt
    69721 tgaggagctg aatctggaga catgactggc agaataagag gcaatccttg agcatctaaa
    69781 actgcatcca cgaatccttg cggtgtatag ctcacttgat ttccttggaa agtatctgtt
    69841 gctcgaatca gttgatttcc ggcaatgccg atgattggtt tcatttgtat tccccctaaa
    69901 gtagacttat tgtaacaagg atttaaaaaa aattaaacta tgtaagactt gcccctatac
    69961 ttatctgttc ttgctgtgtt actatctgta aagagaaatt tcgtgtgaaa ttcatgacga
    70021 tagttgaaaa tattgcttaa tttgttataa taaaaagtaa gcagaaataa aaaggttggg
    70081 cgtaagcttc aaggatctag ttcttcaagg ggtgagaagg acattttatt gaaggggcct
    70141 gcctatacta agttatcttt agaggtacat actttcaatg aaaaaagaaa gcatgtacct
    70201 cttttttaaa tcgaaaggaa gtgaagcaag tgttagaagc tttggaacaa atccgaaaag
    70261 cagaagaaga aaatgaaaag cgtgctcaaa cactgcggca gcagctgaag atctatgcaa
    70321 cagaaaaaga gcaggaattg gaaacgatcc aaacaaacta tcgacaacaa ctaaaacagt
    70381 tggtggaaga aaaagaacaa tttgaaatac aagaattaga aaaagaaaaa atgaaattga
    70441 aagcagaagc agacaaggtg caagcaactt tgaaagatca atatcaaaag catcagagtc
    70501 aagcgatcgg tgcgatcatt gaaagggtga aagaaactta tggccgtcac taagatggaa
    70561 aaagtgaccc tcatttcaga taaaagaaat caggagagga ttttacaagc agtacaagga
    70621 atccaaaacg ttgaaatccg ggatctgtat caaaatagaa caaacaacca gtgggtggag
    70681 aagtattttc cagataccac gattattgat aaagaagcaa aattaagcgc tttaggtaat
    70741 cggttgaaag acatccaaga agctatccaa ttcatacaac accacggcga tagccgtcaa
    70801 aagaaactcc atttgaaacg tcaagaactt tccttacaag atttggaagc caattattcc
    70861 gaagaaaatt tcataaataa attgaaagaa gtccttgatt taaaagaaaa gtgggaacaa
    70921 ctaactgaag aacgtgatcg tttagaagaa gaggaagaat ggcttcttca ttggcaacag
    70981 ctggatattg ctccaagtat gtatgcaagt aagacgacca tttttgagat ggggactgtg
    71041 agtgcagcaa attttgaaag tttcaaggaa gaactgagta agcttgatga cgtttatatg
    71101 gaagaaatag attatacgcc aaaacaagtt tatctttcgt atgttgcttt aaaaaaatca
    71161 gttgctgtta tagaagaaat tgctgggaaa tacgggttca ataaagaaac gtatccttat
    71221 gaacaaaatc ctaaagaaaa actgcaagag accaagcagc aattatccat tgttcacgag
    71281 cagcaaaaga agataacgac agcgttaggt cagtgcagtg gctatatcca agaatttgaa
    71341 tgggtagaag aagtcacact tgccgttgca gaacgagaaa aaataaaaga acggtttatc
    71401 catgcgactt atctgatcgt tttgcaaggt tgggtagatg cagaagaaaa acagaatttg
    71461 ctgcatgtgt taaacgaaac cgtatcagaa gaagatatat acgtcagttt cgaaacacca
    71521 aactcagaag agattcagca ggaagtccct actaaattga aaaaccatcc gcttgtcgaa
    71581 ccttttgaat tgctgactga aatgtacagt ctgccaaaat atgaagaagt agatccaaca
    71641 ccttggatga caccatttta tcttgtcttc ttcgggatga tggtcgcaga tgttggttat
    71701 ggtttgctga tgctcattgg gacaatacta gctcaaaaac tacttgttct accacgcggg
    71761 atgaaacgtt tcgtaaaatt ctttgagatt ctctcgatac catcgatcat ctggggattg
    71821 atctacagtt catttttcgg acagtcatta ccaaaagaac tgtttggcat ccgcttgcct
    71881 ttcccaatcc tatctacgac ggatgacgtc aatacgattt tgattttatc cgtgattttc
    71941 ggtctgatac agattttggt tggattattt gtggcagcaa aggaaaatat caggagaaaa
    72001 gattacttga gtgctgtcag tgatggattt gcctggcaag ggatcctaat tgggatcgtt
    72061 attgcgttgg ttggtgccat gttgataaaa aatacagcat ttgtttacct tggcgctggg
    72121 ctatcgatca ttgctgcctt atgtatcttg atcgttccga ttatccaaac gccgtctaaa
    72181 gtcaaaggtg ctgccaaagg tgcgtataat ctttacggac tgaccggcta tatcggtgat
    72241 ttagtcagtt atacacgttt gatggcattg ggtatttcag gcggaagtat tggagcggca
    72301 ttcaatatgc tagttgcttt catgccgcca gctgctcgat tcagtgtagg gatccttttg
    72361 atcatcgctt tacacgcact gaatatgttt ttgacactgc taagtgccta tgtccatggc
    72421 gcacgattgc agtatgtcga attttttggg aagttttata caggaggcgg acgtgccttt
    72481 gatccgctga aaacggcgga aaaatacgtc aacatcaatc acaagaaaaa aaacaataaa
    72541 taattggagg atttttatat aatgatggat tacttaatta gtcaaaatgg tggaatggta
    72601 tttgcggtat tagcgatggc aacagcgacg attttttcag ggatcggttc agctaaaggt
    72661 gttggaatga caggtgaggc agcagcagca ttgacaacaa gtcaacccga aaaattcggg
    72721 caggctctga ttctgcaatt gcttccaggt acgcaaggtt tgtatggatt cgttattgcc
    72781 tttttgattt ttatcaactt aggaaatgac atgtcagttg tacaaggact gaactttcta
    72841 ggtgcttctc tgccgattgc ttttacaggc ttgttttcag gtattgccca aggaaaagtc
    72901 gcagcggcag gtattcaaat tttagcgaaa aaacctgaac atgctacaaa aggaatcatt
    72961 tttgctgcga tggttgaaac atacgcgatt ttaggtttcg ttatttcctt cctattagtg
    73021 ttgaatgcct aagcataaag gaggaaaagc agatgaacgc cattgaaaaa atcatctctc
    73081 agatgaacga agcagcagag caggaaagag cggcgttaga acaagaagag cgaatgaaga
    73141 tcgatcaaaa ctttgaacaa aaacgtacgc aagttgaaac agaacatcaa aaacaaaaag
    73201 aaaaacaaat cgaattactc gaaaaaaaat accgtcagct aaggaatcgc cagcaagtag
    73261 aagtacgaca agaaaatttg aatgcgaagc aggaattttt aagacgattg tttgcagatg
    73321 cggtaactga aatggaaaat tgggatgaat ctgaacaaat ccagtttatc aaaaatgcat
    73381 tgtattcatt acctttgaca ggaaaagtag cattcattgc tggagaaaaa tcagcagcct
    73441 atctttctca gacgttgttg gatgaatgga acaatgaact tccctttatg atggttttaa
    73501 gtgatgaaac tgttgctgat caagcgggtt ttctgataaa cgatcaagga gttcagtata
    73561 attttctttt cagcagcctt gtacaagata tccaaggaac gatgagtttt gagattgcca
    73621 atcaattatt cgaataagga gggatcagtg tatggaatac cacgaactaa atcccttgat
    73681 tcgcggaaga gagcttgaac ttttgtccaa tgagacattt gaacggatga ttcaaacaaa
    73741 ttctgtcgaa gcacttggtg aaatattgaa atccacgatt tacagtccat atatttatga
    73801 cggatatgaa tatgacttcg aacagaatct tttaaaggag cagagccgtc tatttcgctg
    73861 gttaaaggaa tcagcaccgg agcctgaaat cgtttggatc tatacgatgc gttatacttt
    73921 ccataatctg aaggttttga caaaagctga gatgacaaat caaaatctgg accatttgta
    73981 tatcgacgat ggattttatt cattagaaac cttgaaggat gccattcata cgcaagtttc
    74041 aaatgaactt cctgaaagca ttatggacag tatacgagaa gtacgtgatt attttgaaga
    74101 gtctaccatt cttcagggaa ttgacgtgat ttatgatcga cagtttttga cagagcagcg
    74161 acggcttgcc gataagctag gatatcaaga attgctgaca gaagtcattg cttttattga
    74221 cttgaccaat atcacaacga tggctcgagg aatattgcag aaaagaacat atgggttcat
    74281 gacgacggta ctttccagct cgggaagtat cgaaaaagaa gtatttttga actttgtaga
    74341 taaagatatg gaagattaca cgaattttct attagagaca gattatgctg attttctgcg
    74401 ccctgtcatc cgtgagggaa atattgatct cgtaaagctt gaacagttga aagatgatta
    74461 tctaagttca ttgtatcaag aagcacaaac ccaggctttc ggaccactgc cactactagc
    74521 ctttttgaac gcaaaagagg tagaaagcaa aaaccttcgt ttactggtta tcggcaaaag
    74581 aagccatttc gaatcagaaa caatcagaaa gcgggtgaga caagtctatg acgcataaga
    74641 tcggtgtagt tggcgacaaa gattctgttt tgccattcaa attgtttggc tttgatgttc
    74701 gttatggtac aaccaagcaa accgttcgtc aggcaattga agaaatggca aagaatgagt
    74761 atggcgtgat ttatgtcaca gagcaatgtg cagcattgag cccagaaacg atcgaacgtt
    74821 acaaggaaca aatgatacct gctatcgtat tgattcccaa tcatcaagga tcattaggga
    74881 tagggctgga agaaattcaa aaaaacgtag aaaaagcagt aggtcaaaat atcttatagt
    74941 atgaaaagga gatagaaatt ttgcaaattg gaaaaatcat aaaagtctcc ggacctcttg
    75001 taatggctga gaacatgtct gatgccagta tccaagacat gtgtctagtg ggagatctag
    75061 gagttatcgg agaaattatc gagatgcgtg gcgatgtggc gtctattcaa gtatatgaag
    75121 agacttctgg aattggtcca ggcgaaccgg ttcgctctac tggtgaagct ttatctgttg
    75181 aattaggacc agggatcatt tcacaaatgt ttgacggaat ccaacggcca ttagatacct
    75241 ttatggaaat cacacaaagt aatttcttag ggcgcggagt tcaattgccc gcattggacc
    75301 atgagaaaaa atggtggttc gaaccaacag tagaagccgg agaaacggtg agtgctggag
    75361 atgttatcgg gatcgtagaa gaaacaaaag ttataaaaca taaaatcatg gtgccaaatg
    75421 ggataaaagg aacgatcaaa acaatcgaaa aaggttcatt cactattgat gaaacagtat
    75481 gtgtcattga aaccgaaaat ggtgacaaaa atttgacgat gcttcaaaaa tggccagtaa
    75541 gacgtagtcg gccaatcaaa gaaaaattaa acccggatgc acccatgatc actggacagc
    75601 gagtgattga tacattcttc ccagtgacaa aaggaggagc agcagctgta cctggtcctt
    75661 ttggtgcagg gaaaacagtc gttcagcatc aaattgcaaa atgggccgat gtggacatgg
    75721 ttgtctatgt gggatgtggc gagcgtggaa atgagatgac ggatgtttta aatgaattcc
    75781 ctgaattgat tgaccctaat acaggagaat cgttgatgga acgtacggta ttgattgcta
    75841 atacatcaaa catgccagta gcagctcgag aagcttctat ctatacggga atcacaattg
    75901 cggaatattt ccgtgacatg ggttatgacg ttgctatcat ggcagactcc acttcacgat
    75961 gggcagaagc acttcgtgag atgagcggac gtttggaaga aatgcctggt gatgaaggtt
    76021 atccagctta tcttggttca cggcttgcgg aatactatga acgatctgga agagtcattg
    76081 cattaggatc agaaggtcgc gaaggaagta taaccgcaat cagtgctgta tccccgtctg
    76141 gaggggatat ttcggaacca gtcacacaaa atacattgcg ggtcgtaaaa gtattctggg
    76201 gtcttgattc cagtttagcc caaaaaagac attttccttc gatcgattgg atacaaagct
    76261 attctcttta ttcaacagaa gtagggaagt atatggatca tatccttcaa gctgactggg
    76321 catccatggt caccgagggc atgcgtattt tgcaggaaga acagcagctg aatgaaatcg
    76381 tgcgtttggt agggattgat tccctttcag ataatgaccg tctgacatta gaagtggcaa
    76441 aatccattcg tgaagattat ttgcagcaaa atgcttttga tgatgtcgat acattcactt
    76501 caagagagaa acaattcaaa atgttgaaga tgatcttgac ctttggtgaa gaaggacgcc
    76561 gtgcgttgtc gttaggtgct tatttaagtg agatcatgga cggtaccgta tcgattcgtg
    76621 aaaggatcgg acgaagcaaa tatatcccgg aaacagaatt agaaaaacta gatcaaatta
    76681 ttggtgaaat caagcaaacg atgcaaacga tcgtttcaga aggaggcatg agcaatgatt
    76741 aaagaatatc gtacgatcgg tgaagtcgtc ggtccattga tggcggttga aaaagttgct
    76801 ggtgtcaaat atgaagaatt aatcgaagtc cgtatgcaaa atggcgagat tcgtcgtgga
    76861 caagtattgg aagtccaaga agataaagca atggtccaaa tattcgaagg aacaagtggt
    76921 atcaatttac gtgactcttc tgtacgattt ttaggccatc ctttagaact aggtgtatcg
    76981 gaagacatga tcggtcgagt attcgatggt ttgggacgac cgaaagataa cggaccagag
    77041 atcctgcctg aaaagcattt ggatattaac ggagaagtaa tcaatccagt agctcgggat
    77101 tatccagatg agtttatcca aacaggtatc tctgcaatcg atcatttgaa tacattagtt
    77161 cgtgggcaaa aattaccagt attttctggc tctggtcttc ctcataaaga attagctgct
    77221 cagatcgcgc gacaagcaac ggtactcgat tcatcagatg atttcgccgt agtctttgct
    77281 gctattggaa tcacttttga agaagctgaa tttttcatgg aagattttcg tcaaacgggc
    77341 gcaatcgacc gttctgtcat gtttatgaat ttagcaaacg accctgcaat cgaacgtatc
    77401 gctactcctc gtatggcttt gactgctgca gaatatcttg cttatgaaaa gggaatgcat
    77461 gttttggtta tcatgacaga catgaccaac tatgcagagg cattgcgaga gatttctgca
    77521 gcacggcgag aagttccagg aagaagagga tatcctgggt atctttacac gaacttagct
    77581 actttattcg aacgagcagg aagaatccgc ggactaaaag gatcggttac tcaaattccg
    77641 attctaacaa tgccagaaga cgataaaact catccaatcc ctgacttgac tggttatatt
    77701 acagaaggac agatcatctt gactagagag ctttacaaga gtgggattca gccaccaatt
    77761 gatgtactcc cgtctctttc gcggttaaaa gataagggaa ctggacccgg aaagacaaga
    77821 gaagaccatg cagctacgat gaatcagctt tttgcagcct atgcacaagg aaaacaggca
    77881 aaagaattag ccgtagtttt aggtgaatct gctttatctg atgtagacaa gatctatgcg
    77941 aagtttgctg agcggtttga aaaagaatat gtcaatcaag gattctacac gaaccgttcg
    78001 attactgaaa cacttgatct agggtgggaa ctgctatcga tgttgccaag aaccgaatta
    78061 aaacgaatca aagacgacat gctggacaaa tatctgccag aagggaagtg agttctgatg
    78121 gcacgattga atgtgaatcc gacccgcatg gaattgactc gattgaaaaa acagttgaca
    78181 actgccacaa gagggcataa attattaaaa gataagcaag atgaactgat gcgtcaattc
    78241 atcctgttga ttcgaaagaa caaccagctg cgtcaagaaa tggaagagtc tatgacagaa
    78301 gcaatgtctg attttgtatt ggcaaatgct tcgatcacgg aacctttcat cgaagaatta
    78361 tttgttttgc cggcggaaaa cgttgatttg tctatcgtag acaaaaatat catgagtgta
    78421 aaagtacctg tgatgaattt tgaatatgat gaacagctga cagacacacc tttggaatac
    78481 gggtatttga attccagtgc cgaactggat cggtcaatcg atcggtttac taccctgctt
    78541 ccaaaacttt tggaactgac agaaatcgaa aaaacttgtc aactgatggc gagtgaaatc
    78601 gaaaagacac gtcggcgagt caatgcatta gaatatatga cgatccctca attagaagaa
    78661 acgatctatt atattcgtat gaagctggaa gaaaacgagc gcgcagaagt aacaaggttg
    78721 atcaaagtaa aaaatatggg taccactgac taagtggtat ctttttttaa aagaggaaaa
    78781 cgatgattaa acaaagcaaa caaataaaga aacgtttgcc ggctgttcag cttctcgcat
    78841 taggattttt tctcctgatt ttagttggcg gcggcctact taccctacca ttttttagta
    78901 atagtgggca tgggacaaat tttatcgatg cgcttttcac tgcaacttct gctgtctgtg
    78961 taacgggatt gacaacattg aatacagcag agcattggaa cagtgctggt caatttttga
    79021 tcatgctttt gattgagatc ggcggtcttg gttttatgat ggttccgatt ctatgctttg
    79081 cattgataaa gaagaaagtc agtctcagca cacgtattat attaaaagaa gcgctgaatc
    79141 tagaagaagt atcaggtgtg atgaagctca tgctttacat cctaaaattg gcctttgtga
    79201 tccaattgat tggtacggtt gctttatctt ttgtatttgt gcctgaattt ggctggttga
    79261 aaggtatctg gtacagtttg ttccatgcaa tctctagttt ttgtaatgca gggtttgatt
    79321 tgttaggaga cagtttagcc aatcaccagc aaaatgttta tttgatcatg gtggtatctg
    79381 ctttgatcat ttctggtggg ttaggcttca tcgtatggcg tgatttactg gaatatcatc
    79441 agaaaaagaa gatgacgatt cattcaaaaa tcgcattaac cgttacaggt acccttttat
    79501 taggcggatt cgttgtgttc tttttcacag agcgcaatgg ggcaacgcta gtggaaggga
    79561 atatgtttca acgattggca aacacctttt ttatgagtgt gacacctaga acggctggat
    79621 attattcagt tgattacctc catatgagcc atgcaggtct gattttaacg atgtttttga
    79681 tgtacatcgg cggaacatct gggtcgacgg ccggcggatt gaaaacaact acgttaggtg
    79741 tgttgctgat ccagatgcgt tcgatgttga aaggacgtac gagagcggaa gcatttggcc
    79801 gtaccatccg acaaggcgca gtgttgcggg cacttacttt attttttgtt acgttgacgt
    79861 tgtgtgtagt cgccatcatg attttatcgg tgactgaaac gatacctaaa acttctggca
    79921 tcgaatatat tgcttttgag gtcttctctg cgtttggtac agtaggtctt acgatgggat
    79981 tgacgccaga cttgactgca atagggaaat tgatcattat agcgcttatg tacattggac
    80041 gagttggtgt attgactgtg gtcttctctc tgatgacaaa agcacaaaga acacaatcaa
    80101 aatacaaata tccagaagaa agtgtcatga ttggataatt tcatcttctg acagaaacct
    80161 agtgatttag taaaataaga aaataaaata atttttcttg cttcttggat actttaagtg
    80221 caaaatgttc gtttattttt tgaggcacta cccgttgttg aacctcgggt agtgcctctt
    80281 ttttattgaa aggaatcaat aagatttgat tcctttattt atcaataggt tataattcat
    80341 atttttttat tttttctttt acgatactta gtccagaagc taaaatttca aggttattag
    80401 aggataggga aattcgaacg aatgcatctg gttgcgtacg tgtagtaaag cgtctggaat
    80461 gataaagtcg gataccgtta gcaagaaagt cattctcaat tatcttaggg tcaatctcag
    80521 gatcaactgg aagaattcga tagtaaggga cacgattcgt tggtttttct actttgaaaa
    80581 gagaatcaaa aagctgattg gctctttttg taagacttaa tttagtttct aagatcctat
    80641 ttgcttcatt tgaatggagg atttgagtga tgacttccac atctaatcca gaagttttca
    80701 catttatatt aaaaattgct tgttctatct tgctttggac atgtactgga actacaagat
    80761 aagcaactcg caatccagaa caaataaatt ttgtcattcc agctaagtag attgtttggt
    80821 taggtaataa attttggaaa ggaggaatga tcgtatgttg atagtaagtt gttaaaaatg
    80881 aatggatatc atcttcaata acccatagac cttctttttc aatcacttcg gctaattgct
    80941 ctcgtctttt gtgagagatt tgaaacccta taggattatt acaagaaggc ataagaaaga
    81001 caccatgaat cttctttttt ctacattcct gaatcaatat atcaggtcgc attccttgct
    81061 cgtcaaaatc aattggaacg atctctaaat gatataactg agccaattca atgaaattag
    81121 cgtatgtata tcggtctgtt gctattctat cacctggaga gaaaagtgca gaaagtgtga
    81181 tagccaatcc attttgaaca ccggaaacaa tagatagaga ttctaaggac ggaatgactc
    81241 cttgagtttt taaccaattt gctgcagtag tcaattgaaa atttgtgcct ttgggatctt
    81301 ggtaattaag caaaccaaca agatttgggt tattactagt tgattgaata aacgggacaa
    81361 cgaatttatt acattcttca aaagaactaa ccagaccaaa atcaatgata tgttcggtta
    81421 cttcattggt agagatggtg atggactcaa agacattggg agaaataaat gtgccacttc
    81481 caatattcgt atacagcaaa cctttctcaa ttccatattt ataagccttg ccaacggtag
    81541 taaaatttaa atctaaataa tcagctagct ctctttggga gggtaactga gtgtttttct
    81601 gtaatttatt ctttaaaata tcttgttcta attgttgaat caacgatcga taataaggac
    81661 gcttcaattt ttgtttgtct ggtcgccaag ttaacgggta attgtcataa gaattaatag
    81721 gcattttctc cactccttaa aattgtatac catacaattt taccattgat tgtattgatt
    81781 ttagaagtta atcttttgtg aggagggaat tgtctatgaa aattattaat tttgaggaag
    81841 tagtagcttc ttttagtttt gaagaagcga ttcaagtaat gaaaaaatgt ttttttgatt
    81901 atgaaagtgg taaaatcagc caaaatcctc gattggtgga aattttacct gacggaaaag
    81961 gcaaaaatat gtttgcgatg atgcctgctt atttggggga gaacagatat tttggcacaa
    82021 aagtcattac cgcttttccg gataatcatc agtatcattt accttctcat ttaggagaga
    82081 ttttcttgtt tgatgctcaa aacggactac ccaaagcatt gataaacgca aatgcagtca
    82141 cctggattcg aacagctgct gtatctgcgc tggcaacaga ttacttagca aatccgcatg
    82201 cagaaacact tgctttaatt ggagctggtc aacaagcatt gtcgcatttg actgcgattt
    82261 ctaccattcg tcccatcact acagtgtttg tttacgatat tttagaagaa agacgaaata
    82321 cttttatcgc taaagctaaa aaacagtatc ctaaaataac gtttataaat gcaatatcag
    82381 tagaagatgc agtacgtcca gcggaaatca tttgtacgtt gacctctagt aaagaggcat
    82441 ttcttcaaaa agagtgggta agggaagacg cacatatcaa tgctgtgggc acatttactc
    82501 ctgatacaag agagataagt acatcgttga tggaaacttc tcaaatctat gtagatgatt
    82561 actcagctgc cttaacagaa agcggggacc tgcttatagc catggcagaa ggagatttag
    82621 aggaatcttg tattgttggt acattaggcg aattagtttc tgagaaaaaa acattttata
    82681 aaggagaatc gaggccgacg attttcgacg cagttggtct agctattgaa gatctttgtt
    82741 gtgcagaata tatttataac aaattagaga aaggggcttt aaaatgaact tagattatta
    82801 cgtagttgat gcatttgcag atgaggtgtt caaaggaaat ccagcagcgg tttatgtgct
    82861 agaagaatgg ctgccagaag gtacgatgca aaaaattgcc attgaaaaca atttatctga
    82921 aacagcattt acagtgaaga aaaaccaaga atttgagctt agatggttta cgccagatcg
    82981 agaaatcgat ctttgtggtc acgcgacatt agcaacagca tttgttttat ttaactatta
    83041 caaaatacct gatgaaacga ttaaattttc tactcaaagc ggtaatctat ttgtgacaag
    83101 aattaaagat tattattaca tggattttcc tagtattatg ccgaaaaaag tgccgatatt
    83161 gtctgaatat gaagaagcga ttggggctaa gattaaagaa gcctacttag cacgtgattt
    83221 atttttcgta ttagaagatg aaaaaacggt ggctaaattg cagccagatt ttacagctat
    83281 caaaaatttt gaattaggaa taggagtcat cgtgacagca gaaagtgtgc aaaaagactt
    83341 tgtttctaga accttctttc caaaattaac aatcaatgaa gatccagtat gtggatcagc
    83401 acattctaat cttattcctt attgggcaga aagaatgaat aaaacaaaat tgtcagctta
    83461 tcaaatgtca tcaaggggcg gggatctaga atgtgaatta aaagaagatc gtgtgataat
    83521 aggaggaaaa gcagttttgt tttctaaagg tacctcgttt atttgatttc tttcaaatga
    83581 attaaaaata aattggtgga gagtggcaac cttatagcta caatggttgt taaaaaaaga
    83641 cgcaaacttt ttcaatttaa tgaaaagttt gcgtctcatt ttaattattg gtgtttgttt
    83701 tttattcaat caagagtaaa atgccccata ctaactatcc tcggatgact tcgattttat
    83761 aaccatcagg gtcaatgaca aagtagtaag aaggcgcagt gccaggtaat ccttttaagt
    83821 cagtaatctc aagaccagca gctttatgtt gctcgtgtaa tttttctaga tcatcagctg
    83881 ctatagcgat atgaccatag ccgtctccta gatcatacgc accatgatca tagttgtaag
    83941 tcaactctaa ttcatagtca tccccaggaa gtgtcaaata aacaagtgta aatttgtttt
    84001 ctggaaaatc acggcggcgg ctttcttcaa aaccaaatgc cttttgataa aattcgattg
    84061 atgcttcaag atctttcact cgaacacatg tgtgagccat tttcatagat tcatctctcc
    84121 ttttcctttt actcaatcat aacaaaaaga agtaaggaaa tagttgattt gtgcttgttc
    84181 atgagaaatt tctcatgtaa aatggataga aaataaaact gttaaggtgg aaactattca
    84241 tggataaacc aatttttggt gaaaaaaagc aatttgctga ttatcaaacc cgttatgcag
    84301 catatattgt catagaaaga gatcagcaga ttgcagtaat cgaggctcca aatggtgctt
    84361 tttttcttcc tggcggggaa attgaaggag aagagacgaa agaagaagcg attgtccgtg
    84421 agctgataga agaaatggga attgtggcag aaatttcttc ttatctggga gaagctgatg
    84481 agtattttta ctcgaattat cgtgcaactt attattataa tccaggatat ttctttgttg
    84541 ctgattcttg gaagcgtata ggagaaccaa ctgaaaagac caataaaatt tggtgggtga
    84601 gccctcaaga agcgcttgtg aaattgaaac gtggtagcca ccgatgggca gtcgagagat
    84661 ggatcgaaaa aaataaaaac tgaaagaaag cgagtagatc agctttctct cagttttttt
    84721 atttattaca gtacatattt tttgattgct tcagctacac cgtgctcgtc gtttgatgaa
    84781 gtgatgacat ttgctgcttc tttgacaaga gaaacggcat ttcccattgc tactcctaga
    84841 ccagcatatt caatcatgga taagtcgttc tcgttatctc cgatagccat gatttcatct
    84901 tgatcaatac caaggtgctg tgcgagattc gcaactgccg cacctttact tgcttcttta
    84961 tttagtactt cgaagtaata gggcgcactt ttgaccgttg tgtatttatc acggaaagtt
    85021 tgcggtaaac gcgcaattgc tgcatctaaa atttctggtt cgtcgatcat catcattttg
    85081 acgatgttca tgtctggtgt catttcttca ggtgttcgat attttagcgg catcttgact
    85141 aaacttgctt cgtggatcgt ataagcgctg atatctcgat taggcgtgta gatcgctttg
    85201 tcatcgatcg aatggagatg actgccgaca cggcgtgcca tcacttcgat ctctaggaaa
    85261 tcttcatgtg tcagtccgtg acgggcgatg attttacctg atttcgtttg ttgtacgagt
    85321 gccccgttat aagtaataac gtaatcatta tcttgaaaaa ggttcaactc gtttaactgt
    85381 tcctggacac ctggtaaggg acggccagtg cataaaacga tcgaaacacc ttttgcaaca
    85441 gcagcggcaa tcgcttcttt tacttctttt gttacttctc ttttctcatt taataaagta
    85501 ccatcgatgt cgatagcgac tagtttgata gacataattt cctccaatat attttaattt
    85561 atttcaatca atgcgccatt acggatatgg ctggcaaatt cttgataagt ttcgtcaaat
    85621 aaatcataat gatcacgcaa ggacggatca accatttctt ttggaaagaa aaatcgctca
    85681 tctccttgtt cttgtcccgc taatgcagca acaagctgac taacctgtga taattctatc
    85741 aaagttccgt catttcgcaa aatctcgatt tgtgtgcgat gtctgccttg ttctgggcga
    85801 taaaaatcat aaggtagatc gtagctagaa ttcacagcag tgtaataaac aggattatat
    85861 ccgacctttt ctactaacaa agtgagttct tggactaatt ttgaatcccg gttgccagaa
    85921 aaagtagcag atttcagtgg tttacgattc aaaaaacgtt tagctaaatc atttaaaata
    85981 ggatcagcag attcagacca ttgagtaaag taagtgccca agaccccatc atcaagtttg
    86041 aggtattctt ctaaagtaaa gcttccgtca agaaatggca gaagtaattg agaatggagt
    86101 tcaaaactgc tggcatcttc ttgatacaac tcgtgtgcgc gatgaagcag atgctccaaa
    86161 attacttcca taccacggga aacaggatgg aagtacactt gcacatacat ttgatatcgg
    86221 ctaacgatat aatcttccac tgcatgcatg ccactcatgg aaaaagcgat cccgccttca
    86281 taaggacgaa tcacacgtaa tattcgggta agatcaaatg ttccatattc tgttccagtg
    86341 aaataagcat cccgaagcaa atagtccatt cgatctgcat cgatctgact agaaatcatt
    86401 tggacaactt gtgggttggg gtaagttttt tggatcacac tagctacctt ttcaggaaaa
    86461 ccttcttcta ctcggttaag aatctgatac acttctgttt ctggagaagt gatgatctct
    86521 acagtgatgg cttcatgatt cgtatggaag atatgttcaa atgtatgaga gtaaggacca
    86581 tgaccgacat catgcaacag tgccgcacat aaagtcacca gccgttcctg atcatcccag
    86641 cctccgttgc ctattttttc ttttgaaaaa tttcgagaaa agatatcgca gattcgtctt
    86701 gaaatctcat aaacgcctaa tgaatgagta aaacggctat gttctgctcc gtgaaaagtg
    86761 aaagaagaag tgcctaattg tttaatgcgt cgtagacgtt ggacttcttt cgaattgatc
    86821 aaatctaaga ttacttgatg ctggacatgg atatagttat ggactggatc acgaaaaact
    86881 ttttccatag gcagcatttg atatttataa ggggttgtca taatgtagct cctttatgtt
    86941 attacgttgt tccattctct ggatttggtt gttccattgc tccagctgga tttctttttt
    87001 tagccagtcg gtagaatcct gtaaatcact tgcagaatac agcttttcaa aagcttttgc
    87061 aaatgcttct ttgacttctt ttacaaaaag gggttggtca agcagttctt caagtgttgc
    87121 cattgtagca ggatccactg caggatagcc atttgtacca aagtcttctt ttaaagcaga
    87181 ttgataaaat cgcttcatga cttgcccgcg tttttcctga ttaccgttga cacttaagta
    87241 catcataaca gaaatcccat ttttgatccg acgctgagcg ataccggcaa attttttgcc
    87301 atggatgctt aaatcataag ttccaggaca ataagaatgg gtgatttcga atgcttgtat
    87361 cggtgccttt ggaaaagcgt atttagtcaa taggagcatt tgctcgtaag cgtcatctat
    87421 ggttattttt tttgtgtcac tttgggggaa aatcaaagaa atattcaaaa ttccttcatc
    87481 tgatacgatc cctaatccac ctgaatttct gatcactgga gcgtaacctg catctttcag
    87541 tgtttggatc ccgtcactta gaaaaggagt tcgaacatcc ttcataccta agatgactgt
    87601 gcagtcatat tgccagaaat gtaaaaagat ttgctggtgt tctttagaat attccgttaa
    87661 tatatctgtt aatgcaaaag gggaaaagtc gtttttttga taaatgtgct gatctagtcg
    87721 aatcgcaggg ttcattcaac cggctccttt gtataaattc atattttcta caatattata
    87781 ctctaaaatc aaagagttgt tttggaaaaa aggttttctg taaaaatgga caagttggtt
    87841 gacaaaacaa aagaaactag gaacaatgta gctatgagaa gtaaaggaga atgaataatg
    87901 gaattatcac aaggaacacc gatttcaatc aaattgcgta caaaagtaaa acagcaaggg
    87961 gaagtgcaag atttttattt tgatttgaaa gggcaaatgg tgacaattgg cgatacgctg
    88021 tacatacgtt ataaagagat tcaggaggag acgggcgatg agattcctgt aacgatcaaa
    88081 ttagttccag atggtcatgt acagctgatc cgtgcaggag aaatgcggat gcgtttgaaa
    88141 tttggctata aagaacggtt agaaacatcc tatcgaacac catacggtat gatccagatt
    88201 gctactttta cgaaagaact gcatgttagt ttgaaagacc gtcccacagc agggaaggtt
    88261 cgaatcgatt atgatctgtt catgggaccg gaaaaaatcg gcgaatatta tttgaccttg
    88321 gattttacag cgtaaatata aaagaaaagt ttgatttttt gtgtctgatt ttgtatgata
    88381 aggagtagac tgtgaaagga cgtgtcctga ttggaaatta gtgtatttga aggtgcaaac
    88441 aaaagcgaat tatcaatgat cgaagtagca cacgcgatct tagaacaacg tggcgatgtc
    88501 atggattttt ctgatttagc taaccagatc caaaactatc ttgggaaatc agacagtgaa
    88561 attcgtgatt cactcgcaca attttatact gacttgaata ttgacggcag ctttatctca
    88621 ttaggggata atcgttgggg cttgcgttca tggtatgcta tcgattcgat cgatgaagaa
    88681 gtaaaccatg gaatggacga agaggatgaa gatactccac gtcgccgtaa acgcaagaaa
    88741 gtcaacgcct ttatcaatga tgatgaagac gcgatcgatt acaatgacga tgacccagaa
    88801 gatacagatc tgacagaaga agatgacgat gatctgtttg atgacgatga tgatgaagat
    88861 gaagaaatcg ctgcttataa ttctgacttg caagaaatcg gagcagatga cccgacagat
    88921 gatgaagaag acttgccagg aaatatcgaa gaagatttaa gtatcataga cgaagacgat
    88981 gatgatgaag attatgaaga ggaagaattt tctgactctg aaaaagaata aacattattt
    89041 tcttacgaga ggttgtgaca gagacgatca gcctatcaga ataaggaggt gtgacacgat
    89101 ttttgtcaca ccttcttttt tgtatataaa aatcccaagt aaatacataa aaaataaaaa
    89161 aattgaaact tttagcgcac cttgtacgtc atattaagtg aggcagaaag gagtggagaa
    89221 tgatttttac tggatataag aaaaaacggc agatcgaaaa ataccgtcac ctgctgaatg
    89281 gactcatcga aactgattat caaaaaatgt tccgtatcac gatgaattac gtacatgata
    89341 aagaagaggc cttagatgtg atgcaagata gttttcataa agccctgaac tattttgaaa
    89401 aagaaaaaga gatcgagcat tttagtgcat ggttttatcg gatattgatc cgcacggcat
    89461 tagatagttg gcgcagacaa aaaaggacgc ctgtggactt atttgaaatt caagatatcc
    89521 cccaacagtt acctttagaa acttccgttg cagagctcca tatgatttta gataaaatag
    89581 acagtccgga aaaagagatt ctgatcctct acttttttga aggatttcgt ttgaaagaaa
    89641 ttgcgactat cttggatatg aatgaaaaca cagttaaaac gaaaatgtac cgctcattga
    89701 atgctttacg tcaaatccta gaatgaagga gagaagagtg ccatgtattc ccaaaaagaa
    89761 aatttaaaaa aactaaagaa aacttataaa gaacaagcaa ttcccaaagg gcttaaagag
    89821 gagatccgcc agcgttttat tatcgaagag caatcattta taaaagcaaa gcggagaaag
    89881 agacgtctcc aagggttcgg agtatctttg gctatcgtaa tgattacaac aagtagcctt
    89941 ctttttaata gtcaagttcg aagctttgca gaagatttac ccatcttagg atcagtcatt
    90001 gaattgatct taggcgaacg ctttactgat cgatctgaaa aaatcgatat tcaggtaccg
    90061 aagatcaata cacaaaatga gaaagaaaat aaaacaattc atggattaaa tcaaaaatac
    90121 tttcgcgaag gacaagcaga ttttgaaaaa gctgaaaaag aatatggaaa ttttgaaacg
    90181 gatcattacc aagttttggg agattatcag aaaatcgtag acgataaccg gtttctcgtg
    90241 attgaaaggc agatcaccca aacagcagca gatagccatg ttgaaaaaag atacgacaca
    90301 atcgacaaga aaaacagtgt ccagctctca cttccacttt tattcaaaga tgacacctat
    90361 ctatctgttt tgacaaaaga agtcaaacgg cagatggccg aacaagtcaa ggaagatcca
    90421 tctaagtact attggactga gcaagatatt caagaaggga cgatagaaaa accaacactt
    90481 gttacgccta cacgaagttt ttatttgaac aaagagcatc aattagtttt gactttttct
    90541 caatacgaaa ttgctcctgg ttatatgggt acaccagaat ttgtcattcc taagtccgtg
    90601 acaaaaacga ttttggcatc ggaagattat ttggatcatt agacgagaag tagttgcgac
    90661 tagcagtttc aattttcaag taagtacaag taaataataa gaagagaaaa agagaaagaa
    90721 gagatatagt gaaaagaaat tatttagtta tcagtattat tgctttatcc gtgcttttgt
    90781 ttttcgaaat tacttcggtg gcctccttga tcaccgaagt aaaaggacaa acacactctt
    90841 cggagcattc gtcacaatct ttcaaacaat cagaacaatc aaccattaaa agccaatcaa
    90901 ctgaaacagc taacgtcaaa gaagccattc aagaatcagc ggaaaaggta caaagtcagt
    90961 catcacaatc aacacaagac agtacaaaaa cgagccgaga tccggctgtc aaaagcgtcg
    91021 caatcagctt tgatgatgga ccaggagcga ccacaacacc gcagcttctg cgaatcttaa
    91081 aagaaaaaaa cgtgcatgcc acttttttcg tcttaggaga aaatacggcg cagcatcctg
    91141 aaatcgtgaa gcagacagct gaagcagggc acgagattgg caatcacaca tacgatcatc
    91201 agaatctggc cactctttct gcccagtcga tgacggagga agtgacgaaa gcagacactg
    91261 agatcaaaaa agtcactggc aaaaccccca cttttgttcg tccgccctat ggttctgtca
    91321 cgaatgtagg agcaacgatc atccagcgac cgatcatcga atggtctgtt gattcagaag
    91381 attggaagac aagaaatcct gatttgattt tgcagaagat ccaagcaaca gtatacgatg
    91441 gggcaattat tttattccat gatatctatc ctgaaacgat tcgtgccgtt cctcaagtga
    91501 tcgattatct gaaagagcaa gggtatcgca tcacgacagt tggggattta ttagggcatc
    91561 caacggctgt cgagaactat tatggcagaa acgatcatcg gccagttcag taagtgagac
    91621 aagtatcttt aataaataac acattttaat aagtagttga acacataact accttacttg
    91681 caaaggctta acaatatcta tacaggtaca acaaaaaact gtccaccaat tttctttggc
    91741 ggacagtttt cacttaaaaa taaagaagca actattcgta aattatgcta aaatagcagt
    91801 agaacgcgtc ctgagggaat cgaacccccg tctcaagaac cggaatctta cgtgatatcc
    91861 actacactaa ggacgcaagc actgggataa ttgtaactaa acagataaaa aattacaagg
    91921 ggattggaca aaaaaatgaa atttgagcaa aatttttcac aaaaacagca gcagacacag
    91981 aaactagcca tgacgcaaca gttgcaacag tccatccaag ttttacaata taacagtgag
    92041 gagctgttgg cattcgttga gaatcaagca atggaaaatc cattggtgga agttgttgag
    92101 ccggaatggc agccagatta cataaaagct tcttcatctt cttatgaagg agaagagaca
    92161 aattacctaa atcagattcc tgatacaaaa gggtctttat ttgattcatt gatcgaacaa
    92221 gtccatttga attaccgaga tacttttttg aggaaaatcg ttctttatct tgtagaatac
    92281 atcgatttga acggattttt gacgattagt ttagaagaag ccggaaaaga gattggagct
    92341 acgcctatcc aaatgctcga tgcgttgact ctgattcagc aattagaacc agctggagta
    92401 ggtgcacgta gtttgcaaga atgtctcatg cttcaaacag aacgagatga ttatgcgccg
    92461 gaattagctt atatcgtgtt ggaagaatgt tttgaggaac tggtggagcg aaaatggaaa
    92521 gaaatcgcac aacgtttttc tgttgatcta catgctgttc agcagatatt cgactattta
    92581 caaacgttga gtccaagccc tggccggatt ttcgaccgta gcagcgaatt gtacattatt
    92641 cctgatgtcc gggtattagt ggacgacgat aaaaatgtac aagttatctc aaaccgaaaa
    92701 aatcagccaa atatacgctt tcaagagagt tacttcaaac aaatgtcaca acaagcagat
    92761 aaagaaactg aaaattattt aaaagaacgg aaacaggaat tcgaatggtt gaagaaaacg
    92821 atcctacaac gtggggatac aattttgcgg gttgctcaag tcattgtttc ccggcaaaaa
    92881 gctttcttta tcgacaagga acgtccaatc aagcctctta cgttaaagga agttgcaact
    92941 gagatagatg tgcatgaatc cacggtcagt cgtgcagtca acgggaaata tttggaaaca
    93001 gacttcggtg tatttgaatt aaaaaaattt ttcactacac gaattcctac gaatagtaca
    93061 gaacagacag aagacctttc agcagataca gcgaagaaaa agctgcagga attagtcgat
    93121 caagaagaca aaaacaagcc gttgtctgac cagaaattgg ttgaattgct gaaaaaagat
    93181 gagatagcga tctcaagacg aacagtagca aaatatcgtg atttattagg aatcccgagt
    93241 tcatcaaaaa gaaaacgtta tgataactaa tcagtcaaaa gactagaaaa agtatttcac
    93301 tttttctagt ctttttagtt gaaaaacgag agcaaaactg ttagacttac agtcgtgagg
    93361 ttgagatttc cctttattga tgtgaaattc gaatagttaa tttctttttt tatcgtatat
    93421 gggtcgtttt aagtctacat tggacgtaaa gtgtccaact aaggagatcg ctatgctgga
    93481 tgaaataaaa atgattgaat ctgttgcacc agatattatc gaagtgttgc aagaacgcta
    93541 taaaatttta cgaaatatct attggatgca gccgattgga cgtcgaagtt tatcggaaag
    93601 tatggggatc acagaacgag tattgcgaac agaaacagat cttttgaaaa atctgaattt
    93661 gatcgacacc tcaaaaagcg gtatgacgct gacaactaag ggcgaagaag tttatcaaag
    93721 ccttgaaaac ttcatggatc agcttttagg tacgcatcaa accgaacaac agttggcaga
    93781 atattttggt aaccaacgct gtatcgttgt ttcaggaaac agcgaagagc agaccaaagt
    93841 ggctgatgca ttcggcgaag cgctgagcga agccctagac cgactacttc cagaaggcga
    93901 gaatatcatc gctgtgatgg gaggaactac tatggctgtg gtagccgaac aattgtctaa
    93961 tctggaaaat aagaaacggc ataacctgtt tgtccctgca agaggcggga ttggtgaagc
    94021 gataactgta caggcaaatt ctgtcagtgc aagaatggct gctaaagcaa acggtaacca
    94081 ccgtgcactt tatgttccgg aacaattaag tctggcaact tacaattctt tactcaatga
    94141 gccatctatc caagaagtct taaacttgat tagtgaagcg aattgtgtta ttcatagtat
    94201 tgggcgtgca ttacacatgg cagcacgtcg taagatgact gaaaaagaat tagtcatgct
    94261 gaaacaagca aatgctgttg cggaatcttt tggctacttt ttcaatgaaa aaggtgaagt
    94321 cgtttataag gtccctagaa tcggcataga attgcaagat ttggaaaaag tcccgatcat
    94381 catggcaatc gcgggcggaa aatcaaaagc taaagcaatt cgagcttata tgaaaaatgc
    94441 accaaaacaa acgtggctca tcactgatga agctgctgca aatgagattt taaaaggggt
    94501 aaccctttaa aataaatatt tttttgattt tcataaggag gaaatcttaa atgacagtta
    94561 aagtaggtat taatggtttt ggacgtattg gacgtctagc attccgtcgt atccaagatg
    94621 tagatggaat cgaagtagta gcaatcaacg acttgacaga tgctaaaatg ttggcacact
    94681 tgttaaaata cgacacaact caaggacgtt tcaacggaac agttgaagtt catgaaggtt
    94741 cattcaacgt aaacggaaaa gaagttaaag tattagctaa ccgcaaccca gaagaattac
    94801 catggggcga actaggcgta gatatcgttc tagaatgtac tggtttcttc acttctaaat
    94861 cagcagctga aaaacattta acagctggtg ctaaacgcgt tgttatctct gctcctggcg
    94921 gaaacgatgt tccaacaatc gtttataaca caaaccacga aacattaact ggtaaagaaa
    94981 cagttatctc aggtgcttca tgtactacta actgtttagc tcctatggct aaaacattga
    95041 acgacaaatt tggtgttgtt gaaggattaa tgacaactat ccacgcttac acaggtgacc
    95101 aaatgactct agacggacct catcctaaag gtgacttccg ccgtgcacgc gctgctgctg
    95161 caaacatcgt tcctaactca acaggtgctg ctaaagctat cggtttagta attcctgaat
    95221 tgaacggtaa attagacgga gctgctcaac gtgttcctgt accaacaggt tcattaacag
    95281 aattagtaac agttcttgaa aaagaagtaa ctgttgacga aatcaatgca gcaatgaaag
    95341 aagcttcaaa cgaatcttac ggatacaaca cagacgaaat cgtttcttca gatatcgttg
    95401 gtatgactta cggttcatta tttgatgcta cacaaactaa agtaatgaca gttggcgaca
    95461 aacaattagt taaaactgtt gcttggtacg acaacgaaat gtcatacact gcacaattag
    95521 tacgtacttt agaatacttc gctaacttat aagatagaca aacgtacaag tgtaaattat
    95581 agacatgtac atttaaaagc ggggaagcaa tcgcgcttct tccgcttttt ttgataataa
    95641 gtttattcag gaggaaataa aatggctaag aaaacagtga aagatatcga tttaaaagac
    95701 aaaaaagttc ttgtccgtgt tgacttcaac gttcctttga aagacggcgt gatcactgac
    95761 gacactcgta tcaaagcagc attgccaaca atcaactacg ttctagaaca aggcggaaaa
    95821 gcaatccttt tctctcacct tggacgtgta aaaacagaag aagataaaga aggaaaatct
    95881 ttagctccag ttgcaaaacg tctaggcgaa ttattaggta aagaagtaac attcgtacct
    95941 gaaactcgcg gagaacaatt agaagaagca atccgcaaca tgaatgacgg cgacgttgtc
    96001 gtattcgaaa atacacgatt tgaagatatt gacggtaaaa aagaaagcaa aaatgataca
    96061 gaactaggta aatactgggc ttcattaggc gatgtatttg ttaacgatgc tttcggtaca
    96121 gctcaccgtg cacatgcttc taacgtaggt atcgcttcaa ctggtatccc aacagttgct
    96181 ggattcttga tggaaaaaga aatcaagttc atcggtgaag cagtagaaga accaaaacga
    96241 ccaatgattg caatccttgg tggcgcaaaa gtttctgata aaatcggcgt aatcgaaaac
    96301 ttgattccta aagcagataa aatcttgatc ggtggcggaa tgacttacac attctacgaa
    96361 gcaaaaggaa tcaagatcgg taactctcta gtagaagctg ataaagtgga actagcaaaa
    96421 gaattaatcg aaaaagcagg cgacaaactt gtcttgccaa tcgacaatgt ctgtgcacca
    96481 gaattttcaa atgatgttga aacacaagta atcgaaggag acattcctga tggtttgatg
    96541 gctttagaca tcggcccagc atcagtaaaa ttatttgctg atacattaca aggtgcaaaa
    96601 acagttgttt ggaacggacc tatgggtgta tttgaaatga gtaactttgc taaaggtaca
    96661 atcggtgttt gtgaagcaat cgctaactta gaaggcgcaa caacaatcat cggtggcgga
    96721 gactcagccg cagcagcaga acaattagga tttgctgaca aattcacaca catctcaaca
    96781 ggtggcggcg caagcttgga attgcttgaa ggtaaagaat taccaggact agcagcaatc
    96841 aacgataaat aaacgaccaa gtttgctcaa ttctgacgag taatcgaaca aaaggtgaag
    96901 ggagttttca tgactcccta gccatttttc aataaattaa ggagtgtgtt cctcaatgcg
    96961 taaacctatt atcgcaggta actggaaaat gaacaaaact gcatcagaag caaaagaatt
    97021 tgctgaagca gtaaaaaaca aaatcccttc aaatgacaaa gttgattcag tcatcggatc
    97081 tcctgcatta ttcttacaag aattaatgac atcagctgaa ggtacagaac taaaaatctc
    97141 agcacaaaac tgctactggg aaaactcagg tgcgttcact ggtgaaactt caccagcagc
    97201 tcttgctgat ctaggtgttc attatgtgat catcggacat tcagaacgtc gtgaatattt
    97261 ccatgaaaca gacgaagaca tcaataaaaa agcgaaagct atctttgcaa atggtatgac
    97321 accaatccta tgctgtggcg aatctttaga aacctatgaa gcaggcaaaa ctgctgaatg
    97381 gatcgaagga caaattacag ctggtttagc tgatctttca gctgaacagg tgtcaaacat
    97441 ggttattgct tatgaaccaa tctgggcaat cggtactggt aaatcagctg acgcacaaat
    97501 cgctgacgaa atttgtggag ttgtacgtca aacagttgaa aaactttatg gaaaagaagt
    97561 atcagaagca gttcgtatcc aatacggcgg ttctgtaaaa ccagaaaata ttgctgaata
    97621 catggcaaaa gaaaatgttg acggtgcttt agtcggtggc gcaagcttgc aagcagattc
    97681 attcttgtca ttgttagacg ctgtaaaata attgttgaaa atttgcgaaa aatgcaagaa
    97741 atgtttgcac taatgagcaa aattaactaa aatcgtatat gagggaaatc ccttaggaaa
    97801 aaacaaactc aaaggagaga caaaacatgt caattattac tgatgtttac gctcgcgaga
    97861 tcttagactc acgtggtaac ccaacaatcg aagtagaagt atacacagaa agcggagctt
    97921 ttggccgcgg aatggttcct tcaggtgctt caactggtga atacgaagca gttgaattac
    97981 gtgacggaga caaagctcgt tatggcggta aaggtgtaac taaagctgtc gacaacgtaa
    98041 acaacatcat tgctgaagca atcattggct acgatgttcg tgaccaaatg gctatcgaca
    98101 aagctatgat cgctttagac ggaactccta acaaaggtaa attaggtgcg aacgctattt
    98161 taggtgtttc tatcgctgtt gcacgtgcag ctgctgacta cctagaagta cctttatacc
    98221 actacctagg cggattcaac acaaaagtat tgccaacacc aatgatgaac atcatcaacg
    98281 gcggatcaca tgctgataac tcaatcgact tccaagaatt catgatcatg cctgttggcg
    98341 ctccaacatt caaagaagct ctacgtatgg gtgctgaagt attccacgca ttagcttcaa
    98401 tcttgaaagc tcgcggatta gcaacttctg ttggtgacga aggtggattt gctccaaacc
    98461 ttggttcaaa cgaagaaggt tttgaagtaa tcatcgaagc aatcgaaaaa gctggctatg
    98521 tacctggtaa agacgttgtt cttgctatgg atgctgcttc ttcagaattc tacgacaaag
    98581 aaaaaggtgt ttacgtacta gctgattcag gcgaaggcga aaaaacaact gacgaaatga
    98641 tcaaattcta cgaagaatta gtttctaaat atccaatcat ctcaatcgaa gacggattag
    98701 acgaaaacga ctgggacgga ttcaagaaat taactgacgt attaggcgac aaagttcaat
    98761 tagttggtga cgacttgttc gtaacaaaca ctcaaaaatt atctgaaggt atcgaaaaag
    98821 gaattgctaa ctcaatcctt atcaaagtga accaaatcgg tacattaaca gaaactttcg
    98881 aagctatcga aatggctaaa gaagctggct acacagcagt tgtatctcac cgttctggtg
    98941 aaacagaaga ttcaacaatc tctgatatcg ctgttgcaac aaacgctggc caaatcaaaa
    99001 ctggttctct atcacgtact gaccgtattg ctaaatacaa ccaattacta cgtatcgaag
    99061 accaacttgg tgaagttgca gaatacaaag gtttgaaatc tttctacaac ttaaaaaaca
    99121 aataattctt ttctaatgaa gatacatgat cgactattga aagatagtcg agtatgatca
    99181 cttagttaag taatcgaact ctctacttgc tgaaatatca gcaggtagag agtttttttg
    99241 caactagctt ctgtatatga tgtttacaaa gaatggtaca agaaaagatc atccttgaaa
    99301 aaggaaagct aacaataact agcatcatat aagagctttt aaggatagaa cagtagaata
    99361 ggaatctatg agcaagtcct ctcgtataaa taaaatagga gggaagtagc agcatatttt
    99421 tcataaagtg gctctctttc ttcattttta ctttggttgc tcctatttga aaattcgagc
    99481 acactcaaat acaataaaaa gaaatggcaa gggagaggat tagatgaaaa aagaagaaaa
    99541 aatcgcgatt ttacaagaga tcatccgaat taaatcagtg aatggaaacg aaggtgaagt
    99601 agcagcctat ttgaataagc ttttggcaaa gcatgacata acaggagaga ttgtttctta
    99661 cagagatggt agagataatt tgattgctcg ttaccaaaag ggccaatcag gaaaagtgtt
    99721 aggcctatct gggcatatgg atgtcgtggc ggctggtgat gaatcgtctt ggacctatgc
    99781 accctttgca gcagaaatcc atgggaaccg tttgtacgga cgtggtgcta cagatatgaa
    99841 gagtggcttg gcagcaatgg tgattgccat gatcgaactg aaagagtcag gaaaaccatt
    99901 taacggaaca gtcaaattat tagccactgt cggagaagaa gtgggtgaac taggtgggga
    99961 acagctcacg aaagcaggct atgtagatga cttagatgcc ttgatcatcg gagagccaac
   100021 caattacagt ttgatgtata cgcacatggg atcaatcaac tatacagtca cctcgcacgg
   100081 aaaagaagcg catagctcta tgccagacca aggttataat gcaatcaatc acctaaatga
   100141 attcattacg aaagcaaatg ctgaaatgaa tcacctcgct gaaacaatcg agaatcctgt
   100201 cctaggaaaa acaatccata atgttacatt gatcagtggc gggaatcaag tcaacagcat
   100261 cccaagccat gcgcagctcc aagggaacat tcgatcgatt ccagaatacc caaatgataa
   100321 aatcattgca ttgctgcaat caatcgtcaa tgaattgaat caagagacag actatcattt
   100381 ggaattgatg atcgattaca acaaaatacc tgtcaaagct gatccagatt ctcctttgat
   100441 tcattgcatt cagcaacaat tcagccagcc attaccttta gttggagcgg cagcaacaac
   100501 ggatgcagcc gaatttacga aagctaacca ttccttcgac tttgtcgtct ttgggcctgg
   100561 tgtcgttact ttgcctcatc aagtagatga gtatgttgaa atcgataatt atttggatat
   100621 gatcgaaaaa tatcaaggaa ttattttatc ctacttagcg taagattttt ttaataaatg
   100681 aaaaaacaga gccagattag cattatt
//
LOCUS       DAFLWC010000002        77766 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.002, whole genome shotgun sequence.
ACCESSION   DAFLWC010000002 DAFLWC010000000
VERSION     DAFLWC010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 77766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77766
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.002"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(93..1262)
                     /locus_tag="L1V17_000102"
     CDS             complement(93..1262)
                     /locus_tag="L1V17_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfa13 family transposase"
                     /protein_id="HBN1234899.1"
                     /translation="MNDFTTEIMEILINKGDLDDLFRRHLELAINALLQAELTVFLDY
                     EKYDRAGFNSGNSRNGNYSRSFKTEYGELNLVIPRDRNGDFSQQTLPAYKRTNDSLET
                     TIIQLVQKGITMSEISDLIEKMYGHYYKPQTISNMSKIVSEDVSAFKERTLEAKYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFTIAPTESAYVWKEILQDLKDRG
                     LEEVLLVVTDGLSGIDDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
     gene            complement(1333..1883)
                     /locus_tag="L1V17_000103"
                     /pseudo
     CDS             complement(1333..1883)
                     /locus_tag="L1V17_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299296.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
     gene            complement(2086..2565)
                     /gene="rlmH"
                     /locus_tag="L1V17_000104"
     CDS             complement(2086..2565)
                     /gene="rlmH"
                     /locus_tag="L1V17_000104"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBN1234900.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            2993..4282
                     /locus_tag="L1V17_000105"
     CDS             2993..4282
                     /locus_tag="L1V17_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBN1234901.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            complement(4321..4926)
                     /locus_tag="L1V17_000106"
     CDS             complement(4321..4926)
                     /locus_tag="L1V17_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HBN1234902.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(5131..5595)
                     /locus_tag="L1V17_000107"
     CDS             complement(5131..5595)
                     /locus_tag="L1V17_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBN1234903.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(5617..5937)
                     /locus_tag="L1V17_000108"
     CDS             complement(5617..5937)
                     /locus_tag="L1V17_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBN1234904.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            complement(6081..7160)
                     /gene="pepA"
                     /locus_tag="L1V17_000109"
     CDS             complement(6081..7160)
                     /gene="pepA"
                     /locus_tag="L1V17_000109"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HBN1234905.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            7360..7710
                     /locus_tag="L1V17_000110"
     CDS             7360..7710
                     /locus_tag="L1V17_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBN1234906.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            7933..8880
                     /locus_tag="L1V17_000111"
     CDS             7933..8880
                     /locus_tag="L1V17_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1234907.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(8937..10355)
                     /gene="pepV"
                     /locus_tag="L1V17_000112"
     CDS             complement(8937..10355)
                     /gene="pepV"
                     /locus_tag="L1V17_000112"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBN1234908.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            10504..11349
                     /locus_tag="L1V17_000113"
     CDS             10504..11349
                     /locus_tag="L1V17_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HBN1234909.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            11353..11793
                     /locus_tag="L1V17_000114"
     CDS             11353..11793
                     /locus_tag="L1V17_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HBN1234910.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            11843..12037
                     /locus_tag="L1V17_000115"
     CDS             11843..12037
                     /locus_tag="L1V17_000115"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1234911.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            12173..12850
                     /locus_tag="L1V17_000116"
     CDS             12173..12850
                     /locus_tag="L1V17_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1234912.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTRFRWLR
                     LTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDYFED
                     IQDRPIK"
     gene            complement(13258..13947)
                     /locus_tag="L1V17_000117"
     CDS             complement(13258..13947)
                     /locus_tag="L1V17_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1234913.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(13922..16051)
                     /locus_tag="L1V17_000118"
     CDS             complement(13922..16051)
                     /locus_tag="L1V17_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBN1234914.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLLENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            complement(16099..17436)
                     /locus_tag="L1V17_000119"
     CDS             complement(16099..17436)
                     /locus_tag="L1V17_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HBN1234915.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            complement(17688..18047)
                     /gene="rplT"
                     /locus_tag="L1V17_000120"
     CDS             complement(17688..18047)
                     /gene="rplT"
                     /locus_tag="L1V17_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBN1234916.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(18100..18300)
                     /gene="rpmI"
                     /locus_tag="L1V17_000121"
     CDS             complement(18100..18300)
                     /gene="rpmI"
                     /locus_tag="L1V17_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBN1234917.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(18372..18896)
                     /gene="infC"
                     /locus_tag="L1V17_000122"
     CDS             complement(18372..18896)
                     /gene="infC"
                     /locus_tag="L1V17_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBN1234918.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     misc_feature    complement(18940..19065)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            19216..19848
                     /locus_tag="L1V17_000123"
     CDS             19216..19848
                     /locus_tag="L1V17_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBN1234919.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(19850..20755)
                     /locus_tag="L1V17_000124"
     CDS             complement(19850..20755)
                     /locus_tag="L1V17_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBN1234920.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(20840..21499)
                     /locus_tag="L1V17_000125"
     CDS             complement(20840..21499)
                     /locus_tag="L1V17_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBN1234921.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            21815..22759
                     /gene="mvk"
                     /locus_tag="L1V17_000126"
     CDS             21815..22759
                     /gene="mvk"
                     /locus_tag="L1V17_000126"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HBN1234922.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            22752..23729
                     /gene="mvaD"
                     /locus_tag="L1V17_000127"
     CDS             22752..23729
                     /gene="mvaD"
                     /locus_tag="L1V17_000127"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HBN1234923.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            23742..24827
                     /locus_tag="L1V17_000128"
     CDS             23742..24827
                     /locus_tag="L1V17_000128"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HBN1234924.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            24824..25888
                     /locus_tag="L1V17_000129"
     CDS             24824..25888
                     /locus_tag="L1V17_000129"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HBN1234925.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(26137..26940)
                     /locus_tag="L1V17_000130"
     CDS             complement(26137..26940)
                     /locus_tag="L1V17_000130"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HBN1234926.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(26960..27802)
                     /gene="kduI"
                     /locus_tag="L1V17_000131"
     CDS             complement(26960..27802)
                     /gene="kduI"
                     /locus_tag="L1V17_000131"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HBN1234927.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            complement(27818..28825)
                     /locus_tag="L1V17_000132"
     CDS             complement(27818..28825)
                     /locus_tag="L1V17_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBN1234928.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            complement(28832..29476)
                     /locus_tag="L1V17_000133"
     CDS             complement(28832..29476)
                     /locus_tag="L1V17_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HBN1234929.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            complement(29576..30334)
                     /locus_tag="L1V17_000134"
     CDS             complement(29576..30334)
                     /locus_tag="L1V17_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBN1234930.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIKTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            complement(30461..31612)
                     /gene="fucO"
                     /locus_tag="L1V17_000135"
     CDS             complement(30461..31612)
                     /gene="fucO"
                     /locus_tag="L1V17_000135"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HBN1234931.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            complement(31694..32005)
                     /gene="rhaM"
                     /locus_tag="L1V17_000136"
     CDS             complement(31694..32005)
                     /gene="rhaM"
                     /locus_tag="L1V17_000136"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HBN1234932.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            complement(32007..32852)
                     /gene="rhaD"
                     /locus_tag="L1V17_000137"
     CDS             complement(32007..32852)
                     /gene="rhaD"
                     /locus_tag="L1V17_000137"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HBN1234933.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            complement(32866..34122)
                     /gene="rhaA"
                     /locus_tag="L1V17_000138"
     CDS             complement(32866..34122)
                     /gene="rhaA"
                     /locus_tag="L1V17_000138"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HBN1234934.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(34119..35579)
                     /gene="rhaB"
                     /locus_tag="L1V17_000139"
     CDS             complement(34119..35579)
                     /gene="rhaB"
                     /locus_tag="L1V17_000139"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HBN1234935.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            35732..36601
                     /locus_tag="L1V17_000140"
     CDS             35732..36601
                     /locus_tag="L1V17_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HBN1234936.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            complement(36727..37626)
                     /locus_tag="L1V17_000141"
     CDS             complement(36727..37626)
                     /locus_tag="L1V17_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1234937.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(37791..38615)
                     /locus_tag="L1V17_000142"
     CDS             complement(37791..38615)
                     /locus_tag="L1V17_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBN1234938.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            complement(38626..39921)
                     /locus_tag="L1V17_000143"
     CDS             complement(38626..39921)
                     /locus_tag="L1V17_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HBN1234939.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            complement(39937..40416)
                     /locus_tag="L1V17_000144"
     CDS             complement(39937..40416)
                     /locus_tag="L1V17_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HBN1234940.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(40422..41450)
                     /locus_tag="L1V17_000145"
     CDS             complement(40422..41450)
                     /locus_tag="L1V17_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HBN1234941.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            complement(41467..42573)
                     /locus_tag="L1V17_000146"
     CDS             complement(41467..42573)
                     /locus_tag="L1V17_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBN1234942.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(42802..45399)
                     /gene="adhE"
                     /locus_tag="L1V17_000147"
                     /gene_synonym="adhC"
     CDS             complement(42802..45399)
                     /gene="adhE"
                     /locus_tag="L1V17_000147"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBN1234943.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(45704..46084)
                     /gene="yajC"
                     /locus_tag="L1V17_000148"
     CDS             complement(45704..46084)
                     /gene="yajC"
                     /locus_tag="L1V17_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBN1234944.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(46181..47326)
                     /gene="tgt"
                     /locus_tag="L1V17_000149"
     CDS             complement(46181..47326)
                     /gene="tgt"
                     /locus_tag="L1V17_000149"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBN1234945.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            47544..48242
                     /locus_tag="L1V17_000150"
     CDS             47544..48242
                     /locus_tag="L1V17_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBN1234946.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(48410..51049)
                     /locus_tag="L1V17_000151"
     CDS             complement(48410..51049)
                     /locus_tag="L1V17_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBN1234947.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(51668..52699)
                     /gene="queA"
                     /locus_tag="L1V17_000152"
     CDS             complement(51668..52699)
                     /gene="queA"
                     /locus_tag="L1V17_000152"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBN1234948.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            52892..54067
                     /locus_tag="L1V17_000153"
     CDS             52892..54067
                     /locus_tag="L1V17_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HBN1234949.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            54071..54712
                     /locus_tag="L1V17_000154"
     CDS             54071..54712
                     /locus_tag="L1V17_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1234950.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            54709..55626
                     /locus_tag="L1V17_000155"
     CDS             54709..55626
                     /locus_tag="L1V17_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1234951.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYSFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            55623..56294
                     /locus_tag="L1V17_000156"
     CDS             55623..56294
                     /locus_tag="L1V17_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1234952.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(56835..57323)
                     /locus_tag="L1V17_000157"
     CDS             complement(56835..57323)
                     /locus_tag="L1V17_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HBN1234953.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(57524..57790)
                     /locus_tag="L1V17_000158"
     CDS             complement(57524..57790)
                     /locus_tag="L1V17_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBN1234954.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(57790..58053)
                     /locus_tag="L1V17_000159"
     CDS             complement(57790..58053)
                     /locus_tag="L1V17_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBN1234955.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            58529..58714
                     /locus_tag="L1V17_000160"
     CDS             58529..58714
                     /locus_tag="L1V17_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBN1234956.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(58856..60679)
                     /locus_tag="L1V17_000161"
     CDS             complement(58856..60679)
                     /locus_tag="L1V17_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HBN1234957.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(61277..63982)
                     /locus_tag="L1V17_000162"
     CDS             complement(61277..63982)
                     /locus_tag="L1V17_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBN1234958.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(64288..65235)
                     /locus_tag="L1V17_000163"
     CDS             complement(64288..65235)
                     /locus_tag="L1V17_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HBN1234959.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            65425..65694
                     /gene="rpsN"
                     /locus_tag="L1V17_000164"
     CDS             65425..65694
                     /gene="rpsN"
                     /locus_tag="L1V17_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBN1234960.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(65870..66232)
                     /locus_tag="L1V17_000165"
     CDS             complement(65870..66232)
                     /locus_tag="L1V17_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBN1234961.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(66243..67364)
                     /locus_tag="L1V17_000166"
     CDS             complement(66243..67364)
                     /locus_tag="L1V17_000166"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBN1234962.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(67380..67730)
                     /locus_tag="L1V17_000167"
     CDS             complement(67380..67730)
                     /locus_tag="L1V17_000167"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBN1234963.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(67860..69371)
                     /locus_tag="L1V17_000168"
     CDS             complement(67860..69371)
                     /locus_tag="L1V17_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBN1234964.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(69693..71045)
                     /locus_tag="L1V17_000169"
     CDS             complement(69693..71045)
                     /locus_tag="L1V17_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBN1234965.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(71198..72274)
                     /locus_tag="L1V17_000170"
     CDS             complement(71198..72274)
                     /locus_tag="L1V17_000170"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBN1234966.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            72470..74215
                     /locus_tag="L1V17_000171"
     CDS             72470..74215
                     /locus_tag="L1V17_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBN1234967.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(74495..74932)
                     /locus_tag="L1V17_000172"
     CDS             complement(74495..74932)
                     /locus_tag="L1V17_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HBN1234968.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(74916..76289)
                     /locus_tag="L1V17_000173"
     CDS             complement(74916..76289)
                     /locus_tag="L1V17_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1234969.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(76611..77099)
                     /locus_tag="L1V17_000174"
     CDS             complement(76611..77099)
                     /locus_tag="L1V17_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1234970.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(77121..77723)
                     /locus_tag="L1V17_000175"
     CDS             complement(77121..77723)
                     /locus_tag="L1V17_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBN1234971.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT        22351 a        16541 c        14159 g        24715 t
ORIGIN      
        1 tattaatatt ttataacttt acgcaagatc ataattttgt cgggagcgtc aataattttg
       61 tgtaaatgga aaagcccatt ctgttgatca agttaaaaca ttgattctaa tgtatcatgt
      121 atttctttaa aacctttatg aactcggcat agaaactttt gattatagtt gttgaattga
      181 gatactagaa atctctccag agattcttca ttaggaaatt gctcttttct tttggtatat
      241 ttctttaatt gtttgttaaa accttcaatc aaattagttg aataaatagt tcttctgatt
      301 gacggaggga aattataaaa ggttaatata gcaggattca tgagcaattt aaccactcgt
      361 ggatactgct ttttccattt atctatcata aaccttattt gattatttgc ttcttctttt
      421 gaacttgctt ggtaaactaa tttgaaatcg ctacagattt cttgtcgatc actaacacga
      481 accttatgag cgatatttct agatatatgg acacaacatt gttgaaattg agcatttgga
      541 taaacactat gaatactatc gtcaatacca cttaaaccat ctgttacgac taacaaaacc
      601 tcttctaaac cacggtcttt tagatcttga agaatctctt tccaaacata agcagattca
      661 gttggagcta tagtaaatcc tagaacctct ttagttccat ccaacctgat accaattact
      721 atatagacag cttcttttga tacggtttgt ctttttaagg gaatatgagt agcatccata
      781 aaaatgactg agtatttagc ttctaaagtt ctttctttaa atgccgaaac atcttcagac
      841 acaattttac tcatatttga aatagtttgt ggtttgtaat aatgaccata cattttttcg
      901 attagatcag agatttcgga catagtaatt cctttttgaa ctagctgaat aatagtggtt
      961 tctaaagagt cattggttct tttataagca ggtaaagttt gttgagaaaa gtctccattc
     1021 ctatctctag gtattactaa attcaattca ccgtactctg ttttaaaaga gcgcgaataa
     1081 ttcccattac gggaattacc tgaattaaat ccagctctat catacttttc atagtcaaga
     1141 aataccgtta attcagcttg taataaagcg ttaatagcca attctaggtg acgacgaaac
     1201 aaatcatcca aatcaccttt attgattagt atttccataa tttctgtagt aaaatcgttc
     1261 atatggaagt cctcttttct gtgaatgtgt tgtggtaact ctattctaca gaagggactt
     1321 ccttttttct atttacacaa aatattttac actctcttca acgatattct tgtaagtaat
     1381 tatgccccaa ctaggatttg tgggttcatt tccatctgga gttaaaaaaa caaaaatttt
     1441 tttatagtta gaataattgc gttctatata tatttggtat ttattaagtt gccctccaga
     1501 ctccgaagac agaattttat tttcgatgca caccactatt ttattttttt ccgataccaa
     1561 taaaatatca atattcttat tttctctgta aacaattaaa tcttcatagc tattaagtaa
     1621 agcatcaaaa taattgatag cagctttggt atcatcatta gaatctatat accttttcaa
     1681 aaacatttta aaaaactcat cagataaatt gtgggtttca tttggagcaa acaaaaaagc
     1741 taaaaaatta ctatgtctta tttcattttt agatagctta agtatctgaa atatatttgt
     1801 tttcccagtc catttagata gttttcttca atatcatcca tatcctctaa tagatttttt
     1861 aaacactttt tttcatctat catgtttttt ctccttgcca ttattctaac taaaatttta
     1921 cgtatttgtt tctatgtcta cattatcttt ttaacagtat ctatttttct tttgcaactt
     1981 acttggctac caaagcaaat aaaaaagtta tttataaatt tctccctacc actacctatt
     2041 gctattattt aaaataggga taattttttc tcttaaaaaa tatcattatt tgtggtatgg
     2101 agcccccgca ttgatccgga aggcacggta gatttgctcg acaaggatca gacgcatcaa
     2161 ttgatgtgga tacgtcattt ttccaaaaga gatctgagca ttgcttcttt tcatgacggc
     2221 ttcgctgagt cctaaagagc cgccgataac aaaaacaagg tggctttttc cttggatacc
     2281 taattggtcg atttgtttag caaaagattc acttgtagga tttttccctt caattgctaa
     2341 ggcatagacg tattcttgtt ctttgatttt cgctaagatc cgttcccctt ctttttcttt
     2401 tacttgtctc atttgcgctt cgcttaaatt ctccggggct ttttcgtcag gaacttcgat
     2461 caattcgatt tttgcatagg cattcagccg tttgacatac tcattgatac cttggatcag
     2521 gtatttttct tttaattttc ctactgagat aattttgata ttcatgtttt ctctcctttg
     2581 gtcttcatgc tcactttgtt tattataatc aattttttcg tctatatgtt tattttggct
     2641 atttttgtta aaaagatttc cccaacagtt atgcacaaca tccacaggtt tatccacaga
     2701 aaacagtgtt attttacctt atttcatcac attcattagg caaacatacg ttttataaga
     2761 atttatccac tttatacaca ggctgtggat atgttttatc ccttattttt ccaatcctat
     2821 ccgcgtagtt ttacacagta tctgtggaaa aagaaaatca aatattttca tctgaaaaca
     2881 atgatttttc ctaaagtttt tcataaaaag ttcacagtct caaagtagac taaagtcaac
     2941 aaataagact atactaacag tagataaatg aatgtaattg gaggaggaac acatggatag
     3001 aaaaaatgtg acaccaaaga tgaaaaaaag taaaaataat agcctctggc gtaagttagg
     3061 tctggggctt gttggaggga tcgttggagg actactgaca gctggcattt tttatgcagc
     3121 gatgggcact ggcaacaata gttctactgc tacaagcggc aatcagaatt ctgccggtga
     3181 aacagttgtg gaaaatgtca aagtcaatgt agattctgat atcaccaaag cggtagataa
     3241 agttcaagac gctgtcgttt ctgttatcaa cttacaaagt caaaaccaat caagcggttt
     3301 tggcggacta ttcgggcagc aagaagaaag tagcagctca gatgatagta atttggaagc
     3361 ttatagtgaa ggaagcggcg tgatctacaa aaaagacggg aatactgctt atgtagtcac
     3421 gaataatcac gtagtagatg gccagcaagg tcttgaagtc ttgatgaaag acggtacgaa
     3481 ggtaaaagct gaattagttg gaacagatgc ttattcagat ttagcggtgt tgaagatcaa
     3541 ttcagacaaa gtcgaaacag ttgcctcttt tggtgactca agtgctctga aggttggtga
     3601 gcctgcgatt gcgattggtt ccccactagg atctgaatat gcaaattctg tcacttcagg
     3661 aatcatttct tccttgaacc gacaagtgac aagtacgaat gaatcgaacg aaacagtcaa
     3721 tatcaatgcg atccaaacag atgcagcaat caaccctgga aattctggtg gtcctttagt
     3781 taatatcgaa ggacaagtta tcggtatcaa ctcaagtaag atcgcaagta cttctgaatc
     3841 tacttctaat gtaagcgtag aaggaatggg atttgctatt ccaagtaacg atgtagtgaa
     3901 tatcatcaat caactggaaa aagacggaaa agtgacacgt ccagctctag gtatcacaat
     3961 ggtcgactta tctgccgttt ctactcagca acaagaacaa atcttgaaga ttccttcatc
     4021 tgtaactaac ggtgtcatcg tgacaaatgt ccaaacagct acaccggctg aaaaagctgg
     4081 attgaaacaa tacgacgtca ttactaagat cgatgacaaa gaagtttctt ctggtgtaga
     4141 acttcaatct gctttgtata agaaaaaagt gggagattct gtcaaaatca cttactatga
     4201 aggctcgaaa gaaaaaacaa ctactgttga attgacgatc gatcaatcgg cattaaaaca
     4261 aaatcaaaat agtgaaaatt aataaaaaag aggttgtgac aaagacttgt cacaacctct
     4321 ttattttgga aatgcttctc cgactacggc atcctcaggc aatactaaga ttcctttttt
     4381 tgctggagca tttggcaaat gcaattcacg agcggaacag atcattccat agctatctac
     4441 ccctcgcaaa gttcctggcc agatcatcat tccatctggc atcatagctc ctggttttgc
     4501 aacgacaact ttttgtccag cttcgatatt gggtgcaccg caaacgattt gcaatactgt
     4561 accattgtct acttctgtct cagtaatcga taaatggtca gaatcaggat gtgggacgca
     4621 tgtttttacg tacccgacaa cgatcttcgg ttcatgatca gcttcaagct gttcttcgaa
     4681 tcctgcttct ttgatcaatc gattcaattt cgctaattcc tcatctgtta agcttacttg
     4741 gccgttccct tcgattgtta gatgatcgga gatatggaaa aagttccaag caacaacttg
     4801 accttgttca tctttgatcc gagcaacatt ccatttgcgt tcaacagtgt tttctgttcc
     4861 tttatcgtcg gctataataa ccatcaaggt gtctccgacg tgtgctttgt tataagcaaa
     4921 aatcatgttc tttcctccat tatcctttgc tgagatttat cttaacaaaa aattgcattc
     4981 actgcatgaa atttttttca tgctttattt ccgaagaagc ctcttctgga acaccattta
     5041 ttcgtaacaa gggactgtga caagactttt gtcacagtcc ctttactgtt ttagttaatt
     5101 gattaaaaag gtcgtacaag ttccacttgc ttaattactt ggctgttctt cttcgtcaga
     5161 aacgatcaag acatcacaag gtgaatgacg tatcacgtag ctggctacac ttcctgtcat
     5221 aaagcgttcg actgcattta gacctgactg cccaaccatg attagatcga tctcatattt
     5281 ttttggcaat ttgactgcca tggattcacg aacagaacca tatgcaataa ttccttctat
     5341 atttgtgtaa tcaacagatt tcccatattc tttacattct tcgatcattt ccttggctgt
     5401 ttcagtttgc tgatcgacta gattttgatc aataggtgca tagcccataa agttataaaa
     5461 ttgctgatcg attacgtttg ctacatatac tttcccatta ttacggcgag ccacttctac
     5521 cgcttttttg aaagcagcaa gtgcttgttc actaccgtcg atacctacta aaatattctt
     5581 atattcttga ttcatcttga cccctcctaa cagatgtcag ccttttgtta cactttctag
     5641 gaacgattcg atttcctgtt ttgttttacg atctttattc actagacgac ctaattcttt
     5701 tccgtcttgg atcacgacaa aacttgggat accaaaaatg ttccattcag cggctacatc
     5761 tatgtacttg tcacggtcta cttcaataaa ttgccaatca gaaaagtcat tttcaatttc
     5821 aggcatttgc ggtttgataa aacggcagtc tccgcaccag ccggcagtaa agaaaaatac
     5881 actctttcca gtttctacgt agcctgctaa ttcttctaaa ctatttggga taatcattct
     5941 ttgtcctcta ctttctgttt atgtattttt caattaaatt atacaccttt ctttcgaact
     6001 aacaaacatt gatcctcttt ttataaaaaa aatctggcaa aaagcaatct tttgccagat
     6061 tttatagttt cactatcgca ttattttccg tatacgatcg tatttactgt tgatttatcc
     6121 aaacctttca gtgtttgaat caacatttct cgtgcagctt caaaatcgcg aatactgaac
     6181 atcgtttgat gcgtatggat ataacgtccc actacgccaa tcactgtact tgggattcct
     6241 tcgttttgtg tatgagcagc acctgcatct gtaccgcctt ttgaaacaaa gtattgataa
     6301 gggatattgt ttgtttcagc gatatccagc aagtactcgc gcaaacgagg aagcatgatc
     6361 aaacctggat cttggatacg catcaatgta ccttctccta aatgtccgaa tgtgccattt
     6421 ttcgtcactg tatcatctgc tgcagagcag tctactgcaa agaacagatc tggcttgaat
     6481 ttattgacag aagctttaga accacgcaag cctacttctt cctggacatt cgcgcctgca
     6541 atcaatgtat gacctaatgt ttcattttgc aacgcttcta aagcttctaa taccattgta
     6601 cagccatagc ggttgtccca tgatttactg ataatattct ttccgttggc tgttttgatc
     6661 gtttcagcgt aaggaacgat tgtgtctcct ggaaggacac cgtaactcat tgcctcttct
     6721 cttgattcaa acccagcatc gaacaaaata tcggttactt ctactgattt ttgtccgctt
     6781 gttcctcgca ataaatgtgg gggaacggaa gaagaaatac atggataatt cttaccagta
     6841 gaggttttaa gtgtaaaacg ctgagcagaa acaacgtaag gattccagcc gcctagaggt
     6901 acgactttaa aaagcccgtt ttcttggatt tgtgtcagca tgaatccgac ttcatccata
     6961 tgtgctgcga ccattacacg gggtgcatcc gcttcttcat gatggcgcag accaaaaatg
     7021 ccgcccaaac catctaactg taactcatct accagcggtt ccatatgact ttccatataa
     7081 gcgcgaacat cttgttcaaa accgcttgtt ccttgtaatt ctgttaactc tttgattcgt
     7141 tgaaatgttt tttcttccat atgctattcg tctaaatttc agactaaact cctctcagac
     7201 ttatattgat ctgcggataa aatatgattt tttctgcaga ccgatcgtat ttattatagc
     7261 ttattttttc tggtagcggt tatttatttc aaagaaaata tgagagtgtg gtaaaataag
     7321 cacaaggagt aacaagtgag aagaaggagg tatgtccaca tgtatgaaga aagcgaacta
     7381 agctatttta aaggcgggtt agcagttgga atcggtctag gattattgag cggggtagct
     7441 tcaacgattt ggtatcatcg caaaaaagta ttgtcagcag accaagtact tgaaaatatc
     7501 aagtcatctt ttctaaaaga aggtgcaatc gaaggttctt ggatctcttt tgaaaaggaa
     7561 cctattagga aattcgccgt tcggtcgagt gcttatcggg gaggtctttc tcgaatagaa
     7621 gatggcgaaa ctgtttatta tgaattttta gcagatgctc atacaggaac cgtattagaa
     7681 atttcaagaa aaaaaggtgc aacagattaa tacgtcaaaa aagtgagaga acgaatacgc
     7741 acccactatt caaaagagag gtatcatgtc cttcttttgt agtgggtggt tttttagata
     7801 gagctttcca aacatatatt ccagtatttt ctttttaaat aaatgatatt tagcgggaaa
     7861 aactagcatt tcctttgatt atgaggtatt tttaatttag cttttgtttt ctatagttaa
     7921 ggagagtgaa aaatggaaca acaagaaaaa attgctgttc tgattccttg ttacaatgag
     7981 gaagcaacaa tttcaacagt cattgcagac tttaaacgag aattaccaga agcagatatt
     8041 tatgtctatg ataataattc gaccgatcga acatacgaat tggccgttca aggtggagca
     8101 atcgtaaaaa aagaacctcg tcaaggaaaa ggaaatgtga tccgccaaat gttctttgat
     8161 atcgatgccg actattattt aatggtagat ggcgatgata cttatcctgc agaagctgta
     8221 catggtttgc tcgagaaatt acgttctggt gaagcagata tggtcattgg tgatcgccta
     8281 tcaaatggaa cctactttga tgagaataag agacctttcc acgattttgg aaataacctt
     8341 gttagaaata caattactag aatgtataaa acaaaaattc ttgatgtcat gaccggctat
     8401 cgaggattca atcgtatctt tgtcaaaagt tttcctatta tgagttctgg ttttcaaatc
     8461 gaaacggaat tgacgatcca tgctttagat aaaaaattca agttcgttga aatcccaatc
     8521 gattatcgtg atcgtcctga aggcagcgaa tcaaaattga atacattctc tgacggattc
     8581 aaagtgatca tgatgattat taaaatgttt aaagattata agcctttgct tttctttggg
     8641 atttggacca tcttcttctt tttatttgga ttggtcacgg ggattcctgt gattcgcgaa
     8701 tatatgctga caagctttat tacacgcatc ccttctgcga ttttaagtac tggattgatg
     8761 actttagcac ttctttcatt agtaacaggg ttgattttgg atacagtcgt cacgaacgct
     8821 aagaaagaat atgaattgaa tctatatcat gtttatcatg aataccacag tagaaagtaa
     8881 aaaaaggatc aagactgcaa aaataatttg caattcttga tcctcttttt aattaattat
     8941 ttcgccaaac gatagatggc atctgcatag attgctgttg ctctgaacaa gtcatcaaga
     9001 ctcataaatt cgtttgcttg atgcattgta tcagtatatc ctgggaacat cgctccataa
     9061 gcaacgccac gtttcaacaa acgtccgtaa gttccgccac cgatgatttg ttcgtagcct
     9121 ttttctccag tgtggtcttc atagacttgc aataatgtag ccaccaatgg atcatccatt
     9181 ggtacgtaat gtggttccat tacgcgagca cctcgagtaa ctgttgcgcc ttcttgcccc
     9241 actgtttgtt cgatgtcact ttgcaatccg tctactgtta caccttttgg aaaacggaaa
     9301 ttcatattga tgaagttcgc ttcctctgta ccattttctt caaaagcaaa tagtccagca
     9361 ttcattgtca atttgcccat tttttcatct tcataagcga ctcctagttt ttctccataa
     9421 aaatcttcat ggacataagc agctgctaca tggataaatt gtttagcaga tcctaggaat
     9481 tcatagttat ctaagaacaa tgccaagaaa gaacctgcat tgataccaga ttgtgggctt
     9541 gcaccatgtg cgcctttacc aactaattcg atttttacat acgtattgtc cgcttcaatc
     9601 gttccgctta ctggatttgc ttcgatgaat tggtaaaatg cttcttccat cgcgatagct
     9661 gcatctgcac ttggtacttg aagtgctgca gttgctgttc ctggcaccat attttcgcga
     9721 agtccggaaa caaaagattt caagacataa tctcctgcat tgtcgccttt gaagcgtaaa
     9781 gctaaagaaa catttccttt ttcaccattg atgattggga attcagcatc tggtgagaaa
     9841 ccaaaatctg gttcttcttc atgttcgaaa taataagcca tatcgcccca gccgctttct
     9901 tcatcgctgc cgactacgaa gcgaactttt tttgatagtt tcaagtcaag ttctttaatg
     9961 atcttcatcg catagtaagc tgccatactt ggacctttgt catcgcttga tccgcgtgca
    10021 aagatctttc catccttgat tactggttca taaggatctg tgtcccagcc atctcctgca
    10081 ggaacgacat ccatgtgtcc aaatatccct agcgtttcgt ctccttcgcc aagatcaata
    10141 tgccctgcat agttatcgac attttttact ttaaatccat cacgttcgcc ataagctaac
    10201 atatgtttca atgcgtcgcg aggtccaggt ccaaatggtg catctggtgt tacttttgag
    10261 tcatcgcgct cgctgttgac acgtaaaaga tttttcaagt cttcaagcaa gtcttcttta
    10321 cgtgcttcta cttctttttg ccaatcaatt gtcataaagt taatcctcca cttatttaag
    10381 tcttcgtgtt catgatacca caaattacag aaaaaaatag ttcaaaaaat ctgacaattc
    10441 cttttcttat ctgtttttct ctaaaaaaaa tatacgctat aatgagtaaa aggaggtttt
    10501 tagatgctga taaacgaaca actagtgaaa agagtcatca cacctcgtcc aaaaatttca
    10561 cataaaggaa catttggacg tatcgttttg attggcggca atgaacaata tggcggagca
    10621 atcattatga gtgctttagc tgccgtacac agcggagcgg gtctcacgac tgtagtaact
    10681 gatgaaaaaa atcggagtgc tcttcacagt catctgccag aagcaatgat tgtagtttgg
    10741 acggatactg accagtttct ttccgtaata aagcaagcag atgtactctt gattggtccc
    10801 ggattgggta cttcttctaa gagtttggaa cgtttcaaac aagtactaga aaaccaatca
    10861 aaagaacaat ggctggtgat tgatggctct gctttaagtt tacttgctgc taatcatctt
    10921 ttgctaccct atcccgaaca aactgtactt acacctcatc aaatggagtg gcaacggttg
    10981 agttctctac cgatacaaga acaacgggat aaagaaaaca aaaagaagca acaggaaatc
    11041 ggtgctgtgc tcgttttgaa aagtcatgag acaaaaattt atggtcacca gcacttctac
    11101 accaatcctt taggttctgc tgctatggca acgggcggca tgggtgacac tttagctggg
    11161 atgatcacag gatttttagc ccagtttcct caaaatgacc aaacgattgc agcagctatt
    11221 tatcttcata gtttcattgg agaccagctg gcaaaagaac aatatattgt tttgccgaca
    11281 caaatcagcg aagcacttcc gaaatggatg aattattttt gtaaaaaatc aatggaaaac
    11341 gaggcatgag tcatggagaa atttacaggt tatgtgcgag aaccttttta ttatgaaaca
    11401 gatcaaatgg ggattattca tcacagcaat tatatccgct ggtttgaaga ggctcgggta
    11461 gccttattgg tacatctagg gtttccctat aaaaaaatcg aagaatctgg gatcatcatc
    11521 cccgttctgg aagtaaattg cagctataaa gaaatgatcc attacggaga aaaagtgagc
    11581 atccatccaa ctatccaaaa gtatacgggg acacggttgg attttagcta cgaaattgtg
    11641 ggaactgaag acaaaaaatt aaaaactact ggcagtagta aacactgttt tttactttct
    11701 gattcgcaac gattagtgaa gctgagcaaa gtcaatccgg agttagatca gttattccaa
    11761 gcgtacgctt ctttggatga tgtaaattct taataaagac cgtctaagca tttttcttgt
    11821 attgtgtcga gtagttcgta taatgaaaag aaaaaagcag gtgatcccca tgtatgtcgt
    11881 taaagtaatg cacggttaca tcgataaaac tggctgtcgc actcgggaaa aaaacttaga
    11941 caatctgctc attttcaaag acaaaaaaga atccgaagct tttgctaaaa gaatcggcgg
    12001 tcgtgtcaaa ccgatccaag aggtacgacc agattgattc aatatttttc ttttcgaggc
    12061 tctaataggc atgcctatca gggctttttt tgcagactgt gtttttatgc ccacacgatt
    12121 tgtaagcgat ttatgttata atagattata tctgcataga aaggaaggtt aaatggttat
    12181 caataatttg caacagcaag cttatgaatc tatacgtaaa caaatcattt attccgagtt
    12241 agcacctgga agtaaaatct ccgataaagt gttagaagaa caactagcta tcgggcgtac
    12301 accgattcga gaagcactga tccaactgcg caatcaagag cttgtaaaaa ccattccaca
    12361 gtccggcact tatgtttcaa aaatcgatat ccgatctgct tcattagccc gttatacgcg
    12421 ggaaaagttg gaaaaaccga tcctgcaaga atgcagtgcg aaaatgacca agcaagatca
    12481 agctaaacta gaaaaaatac tagaacaaac cgatcaggca gtaatcgctc aaaataaaaa
    12541 agcttttttt gatttggata ctgattttca ccgaacttgt tatgaaattg ctggaaaacg
    12601 agaaatttgg gattggctag aaagttatag tacgcgtttc agatggttac gtttgacgat
    12661 ttcagaatta gactggggtc gagtattaga tgaacatcag acaatgcttc aatcaatgat
    12721 tgatcataac tttgatgaag tcggatttct ttgcacgatg catttacata tgattatcga
    12781 ggagcaagaa tacgtgattc ataattaccc cgattatttt gaagatattc aggacagacc
    12841 catcaaataa gaggttttgg aatcagcgtt ttgacctgag tattagagaa agaaacggca
    12901 aaatagttcc tcatattttg ccgttttttt tgagctaata ccgagggtca gctgattgca
    12961 caccgtttat tgagaggttg tgaaaaagct gccctgcatc aagtaataag aacagccaag
    13021 taaaaatagc ttcttatgtt tttaacttgg ctggacttat taccgcagat gcaagctttt
    13081 gaacaccgtt ttccaagagg tcgtgagcct gccgttcatc tccgagtcac aaggaacaat
    13141 ttcaaaaaac agcttctcat gtttgttgaa tattttgact tgtgaccgag gagttgacag
    13201 gagaacatcg tttattcgga aaaaaaggac tgtgacacga cttttgtcac agtctcttta
    13261 tttgtaatct aaatcatact ccgtacatct tttttctatt ttttttattt cttctaagat
    13321 cccttggcta cgaatttcat tatatggcca aagtaagact gcctctaata cataaggcga
    13381 aaaatcgctt tgattcatct cttttgaaaa actcatcgct gctatctcgc tcaatgcacg
    13441 aatgtttgat tgatgtgtat aaaaaggcaa ccgccacagc acaatttttt cgctttgcgt
    13501 ataaattccc ttaacagaag cttcgatgtg gtgaaatagt tcatgtccaa taatcaaagc
    13561 ttgcgctgtt tctttagaga tcgaagctag tcctgaacat tttaattttt ctaacggctc
    13621 cgtcatcaat cgaatccctt catcttctgc ataagttgca aaagtgattc gttcgtttat
    13681 ttgctctgat tcacaggaaa cgattggaac agccatttgt tcacaaattt ctcctacatc
    13741 ggcaaaaggg tacttttttt tgatgctaca tgccgtttcg ataccacaat cgattgattg
    13801 ttgtataaga attttctgct tggacaaagg aatctttttc caaaataaat ctcgccgaaa
    13861 ctggtagaat ccccaaattt cttcggggat ctgttgtaat tcgtttagta actcttctaa
    13921 cttatgtttg tttgatattt ccggcaacga cgatcacttc ttcctccggt tccatagtag
    13981 atacttccag atccatcaaa agctgtagtt gttccagatc cgtcgctgta aaatcagaga
    14041 ctcttgctcc taagcagaga taaaattctg gtcgggcaat caattcagtt tgataaactg
    14101 ccatatcttc ccaaagttgt tcgacagctg tcatataatt ggctgcagtt gttttcatac
    14161 atgaagcatg tccacgttgg accttgataa atcctttttg atcgatgatc cgaagacttc
    14221 cagcattttt tgaacgattc tgttcgccgc atacataaaa gaaaggtgta ttttccaata
    14281 agcaaacttc atttttattt aatcgcatat cctctgcagc aagctctagt gcttcttctg
    14341 ttgtgatctc cttggttaga tcggttgctt tcacttccgt agaaccagta gcgatagccg
    14401 ttacttttga agtctgtgga tcgatttcta cgtggacttc gatcgattct ggtgtagcgc
    14461 ctgattcaat cgctttattc atcgcttcat ttttcaacga tcgtatatct tctttacttg
    14521 gcgaagggat gatacgttct acaacatctc ggaccattgc aagtgctaca ccaatagaag
    14581 aaatcacttc ggcgttttca ggaatcgaat atttcacacc cattttatta ctaaagtaag
    14641 taatcaatga ggcagcgccg ccccctacac ctacaagaga aatctgatct ttctccaagt
    14701 gatacttgtc tgccaattct aaaatcaccg gttcaatctt agcataggat ttttccatga
    14761 tctgttctgc gatgtcttca accgtcgtat gacaataatc agctaatgct tggatggctt
    14821 ttcgtgcaga tgggacattt ccataagaaa aatgttcttc ttgcactaat ccaaggacat
    14881 tggctgcaca tgtatttgta atagtcactt cttctccgtc ttccatcact accttgacgt
    14941 aatcagcagg gtctccttct ttaggagaga aaaattcaac cttaggacct ttgatttttt
    15001 ctgtctccgt aaatactgca taatctagac cggcaatatg tgcagaacgt ggaccgacat
    15061 cgatgattcc tgactgatta gcccgtacca tcgaaccgcc tgccacacct agaacccgaa
    15121 catctaatga agagatatat gttgggtggc cacctacaat tgaataatcg attgctggac
    15181 gtccattttt aatgaccccg atattggttg ttgttccgcc tacttcaaaa taaacaccat
    15241 tagacgctct caagtacatc aaagagccca tgactgatgc tgctggaccg gaaagcatgg
    15301 ttaaaacagg tcgttttttc atttcattga tttccattac tccgccgtct ccgcgcataa
    15361 tcatcaaaga aacattgacc cctgcttctc gtacggaatc ttctgtagag gttgccgtat
    15421 ctagcatttt tggtaaaata gatgcattga ttgctgctgt ccgagttctt cttgtcaatc
    15481 catataattt tgtgatgtca gaagccatcg ttgtagggat cgattttacc gatgctgctt
    15541 cataaacaac tcgttctggt tccccattat ctactccaaa tgccatagaa gaaaccaaga
    15601 cctccgctct ttctctttct aaagaagaaa tcgtttctga aacacggtct acatttaagt
    15661 gtttgacagg taagaatgca ttgacaatct ctattttttt cttattccct aaatcgatat
    15721 cgttcaatct agtttgtcgt tttgctaaaa aaccttctaa tccacctttt gccatcccga
    15781 ttacgccgac ttttgctacg tctccttcaa tcagtgcatt agtcgcttgt gtggtagaat
    15841 gtgcaacaaa cacaacatct tctggactga tattattttc cagcaaacaa ttttgaaaag
    15901 actgaacgac acctgcggct actccacgga catcatcgtg ggttgttttc actgaagatt
    15961 ttccgatgat ttcgtgcgtc gcattatcga ttgcgactgc tttcgtatgt gtaccgccaa
    16021 catcaattcc cattcgcaca aaacgtttca ttttcttttc ctccattcat ctaatcgttt
    16081 ttatcgacgt tttgtttact aggcgttccc gtacaataag aacgtgatca ggcataagat
    16141 cgctccgatg atccaaccag ttgggatgga tttcttcata tattctcgag aagttacttt
    16201 tgtataacct aatccccaag caacccaaga ttgtgtaata tctaaatgct gaggagcaat
    16261 cgttgtgatt gcaaataacg ggaacaaaaa ggctggcgac atcgttggat taacagctaa
    16321 tacgacagct aaaatagctg agcctgaacc gactagattc attggaccgc ggaaaaatcc
    16381 tagtggtgtc aatatagcaa atacgattgc caagactaat ggtgattgcg gtatccaatc
    16441 tccaaaaata gctgaaaaat aaggagaagc atacgcagct gaattattga acatcgctaa
    16501 ggtcatcaag aaaccaacca ttggcgcaac atctactgcg ccatctgtaa ataatttcgc
    16561 aaactgacga cagatttctt tataacctcc gcgcaatttt ccagtaaaca gcaatgccca
    16621 gatacctgct agaataaaac ctaagatgat tggaagatct aaaagaacga cccctaaaac
    16681 tggtaataat acggctaacc atgagatcat tggtgcgtcg ccaccttcag ctggtacgtt
    16741 tgctgccatt gcatagcgtt tctttttgtt cattgatata ttagcgaccg ttagtaccac
    16801 aactaagctt acaatcatcc caatcatacc aatttggaaa tagtcattat aagtatagct
    16861 ttcagccgct ggattgaaac cagcataaat cgtttgatat tgtttgaaat tgacgatatt
    16921 agcaaagatt ccagccataa tcgagcccat aaatgagaac agtgcaaccg gtactgaaat
    16981 acctaatgac atcaagattg gcaacacaat aactgcaata gaaatcactg gtccgattcc
    17041 tgtcatcgac atgaatataa cagcggttac aatacatagt aagctcatcg tgattcttgg
    17101 cttgtcccct ccaagttcaa ctacctttcg aatcagggta gctgcgattc cgctatctac
    17161 tagaacacgc ccgaaaaagg caccaaagaa gacatttacc aagatcgatt tggcgtactc
    17221 agctggcccc gtcgtataga tatgcgtcaa cacatcaatt actccttgcc cttccatcgc
    17281 cgggtttggt gaaaacgtgt ttccgactag cgctaatccc atccatacag tagccatgat
    17341 ggcaaagccg accatcaagt tgtagccttt tacacagtac cagaccatga aaaagaatga
    17401 gataactaac aaaataccaa taataatatc actcatgtta ttcctccgtc cattttgttt
    17461 ttctgataag caaactaata tatcagtcaa actcattcta acttatgtag ttagcgcttt
    17521 cattaaaggg tgaccataaa tgttcagttt tcaattaaaa aaccttaatt atgctatttt
    17581 agacttatac gttattgtcc tgtttcattt gatggaggat tgtaaataaa aaaagaggaa
    17641 agaacataac ttttcgttat cttctttcct ctttataatt gtttagctta tttagccaaa
    17701 gcttcttttg cttggtcagc caatgcagta aatgctgctg catcgttaac agccaagtca
    17761 gctaacattt tacggttgat gtcgatttca gcaactttca aaccgtgcat taattttgag
    17821 tagctcaagc cattcatacg agctgctgcg ttgatacgag caatccacaa tttacggaag
    17881 tcgcgtttct tttgacgacg atcgcgatat gcgtagttgt atgaattcat tacttgttct
    17941 tttgctgttt taaataaagt gtgttttgaa ccgtagtaac cttttgctaa ttttagcact
    18001 cttttacgac gtttacgagt tactgttcca cctttaacac gtgccatgta taattcctcc
    18061 taataaaaat aaatcttcag attctgttat ttgtacttct tatttcattt ttgctagttg
    18121 ttggcgaata cgtttgaagt cgccactaga aaccatgctt gctttacgca attgacggcg
    18181 ttgttttttt gttttgccgt ggaaacggtg acttgtaaac gcgcggaagc gtttcaatcc
    18241 gcctttacca gtacgtttga aacgttttgc tgatccgcgg tgtgtttttt gttttggcat
    18301 gactatattt cctcctcaaa atctttcgtt atccgactat cggctgtcca acagccagtt
    18361 agtcattcaa attacttact gtcgtttttc ggtgccagcg tcaagaacat gctgcgtccg
    18421 tccattttcg ctttttgttc cactgttgca atatccgcag tttcttcagc taagcgattc
    18481 aagacttttt gaccaatttc tttatgggta atggcacggc ctttgaaacg gatagaagct
    18541 ttcactttat cgcccttttc caagaactta cgtgcattac gaagttttgt attgaagtca
    18601 ttcaagtcga tcgtaggact taagcgaact tcttttacat tgatcacttt ttgtttttta
    18661 cgcgcttcgc ggtctttctt ttgttgttcg aaacggtatt taccgtagtc catgattcgc
    18721 gcaactggtg gtttcgcacc aggggcaact aacacaagat ccaagtttgc ttgttctgca
    18781 atattcaatg cttctgcttt tgtcttaact cctaattgct caccatctga accgatcaat
    18841 cgtaactctc gtgcacgaat gccgtcgtta accatcatat cctttgctat ggtcattcac
    18901 ctccaaatat tatgagagaa agaaaagctt accgaataaa cggcaataaa aaaacgagtt
    18961 ctcttacaga acccgcgcgt acttcaccta atagaaccag tgaaaactat ctagcccagt
    19021 gacattatca actaaggcga gaagcgggtg cttctgcttt tatttctcaa ccatcatagt
    19081 atagcaaaaa ctaatctttt tgtcaatgtt tttcatacag tttgtcttcc ttttctgaaa
    19141 atgattagat tagcagactt tctagcagtg attcccgctt ctttgctata ctaaagaaaa
    19201 acgaggtgaa cccacatgaa aaaaatcgaa cctattccac cttctcttcc tcttcttaca
    19261 aagggagagt tttatttaga agatgaggag atcttctctg gtcttctgat caacgggggt
    19321 gaccaaagct atctcgatgc caaaaatatg gtattaagag agagtcatat ccaaaaactt
    19381 acgatgcaaa aaacagtttt acgtcatttt gaatgcagta atgtcatttt tgaaaaatgt
    19441 gatttttcca atctggagtg gattggtggc agtttccacc aagtcgtgtt tcatcaatgt
    19501 aaattaacag gtacgaattt tgccgaaagt tatcttcgag actgtacttt cactgattgt
    19561 attgcttcga tggcttcctt tagtagtaca aacttgaaag ctgtctcctt cgatcattgt
    19621 caattagaag acagcgaatt ttatgaggtc acttggaaaa accttttttt gtctgacaat
    19681 cagttgaccg gttcgaactg gtttcgaact tctctgaagg gattagactt tacgactaat
    19741 ttcttcacag caatcgcttt atctcaagat tctttggcgg gactaatcgt caaccaagag
    19801 caagcacttg tgatcgccca agcccttggt ttgcagatca aagactagat caacgaatcc
    19861 gccgccacag tgcaataagc atccaaatag ataagaccaa actgatgatc aaggcgattc
    19921 cccatccgaa aacggaatgg gtaaagggta actggagatt cattccgaag aatcctgtca
    19981 caatagttgg aacggtcaag atcagcgacc agaccgtcaa aaatttcatc gtgtcattca
    20041 agttgttatt cagcaaatta ttataagtgc cagagagctg gtctaaaatc tgcgaagcta
    20101 agttcgtcat ttcaactgct tgtcgtgctt cgatcagcgc atcgtccaac tcttcttttt
    20161 ccttttctga caacttgcga taaatagcca atgccttgat ttgttctaaa agtactacat
    20221 tttgttttgt tcctgtaact aagtaaacca aaccgatctc taaatctgaa agttgcagca
    20281 gattcttgtt cgttgttttt tctcttaatt tcagattaag ccgctgacgt tcactattca
    20341 cttcctcgat taaaggaaaa aaggaatcag aaatcaaaaa caatgtacga aacaataaac
    20401 tgtatacact catgtctggc attcgttcca aaagcgatcg aattagtcga atcacgtact
    20461 cggtattcgg cgtggtaaat gtaaacaaac cgtcttcttt taaaataaaa gcgataggac
    20521 tagtttcata atgattatcg actttttgct ggtgcggaac atttgataca agcagtaacg
    20581 cttcatcaaa agaatcgtac tctacgcgcg cccgttcatt tttatctaga gaataagtca
    20641 gcatctcgtc actaatgcca tattcttctt ttaagttttt aacagctagc acatcgtttt
    20701 gctgtacatt gatccaaaaa ttacggtctt gattaaaata gtgtttttcc cgcatactct
    20761 atcctcctga catttgtttc cagtataaag aaaaaagtcg ctcaaataaa ggtttaccct
    20821 ttatttgagc aactgtaaat caaatggcta ctttggtttg gcgaatctct gctaattttt
    20881 cttcgatcat tttcaagact tcttcttttg cttgaggatc ttccacaaaa ttatagcggt
    20941 ctccatcgat ttggattttt ggactttctt tgtattcttc ataccattga tcgtaacgtc
    21001 tgttcaattc tttgtaataa tcgtatagac ttggatcaaa ggacaattgt tcatacgaac
    21061 gaccacgttt ttcgatacgc tccaacatcg tatcaaaaga tacacgaata tgaactaata
    21121 aatccggatg ttttttatgg gcagcatagg gaagttcttc catcatgttt tccagcagtt
    21181 catcatacac acgaacttct gtttctgttg ctcttcctag atctgcattt agatggaaaa
    21241 gcagtgaatc ttcataaatc gaacggtcca atacattatt gtcatctttc attgcttgtt
    21301 tgatgcttgc aaaacgttta ttcaaaaaat aaatttgcag caaaaaagca tactgttcag
    21361 ggtttgcata aaataagggc aagacttcat tatcatcaat cgattcataa aatgcctgac
    21421 tatcaaagtg ttcagccatc atttctgtta aacttgattt tccggcacca attgtacctg
    21481 ctaaaacgat cacgctcatt tacctccagc tcacttcatc actaaatatt gtgtttaact
    21541 ccaacctttt taaatatacc cccaatatct agtagtgtca attgtatttt tttctagtca
    21601 aagaagaaaa aaagtcaaaa aattcttaag aaaaaagtgt tttttcttta gaaaacgtat
    21661 tcttagtttt acttctgaga tggttttagt aaaataaagg aggaatgttt tttgagaccc
    21721 ttagtggaca aaaaaattcg tgaagcagcg caactcgttt tgggcgcttt attttttgct
    21781 taaaaatcac ttttacgtga gaaggagtta gattatggca aactatggcc aaggagaatc
    21841 aagcggaaag atcatattga tgggcgagca cgcggttgtt tatggagaac cagcgattgc
    21901 ctttcctttc tatgcaacaa aagtcaccgc attccttgaa gagctggatg caatggacga
    21961 tcaactggtt tcttcctact attcaggaaa tttagccgaa gctcctcatg cattaaaaaa
    22021 tatcaaaaaa ttattcattc acttaaaaaa acagcatgac atccaaaaaa acttgcaact
    22081 gaccattgaa agcacgattc ctgctgaacg tggaatggga tcaagcgctg cagtcgccac
    22141 agcagtcact cgtgcttttt atgattactt agcatttcct ttgtctcgtg aaatactatt
    22201 agaaaatgtc cagctttcgg aaaaaatcgc ccatggtaat cctagtggaa tcgatgcagc
    22261 cgctactagc agcttgcagc cgatttattt tacaaaaggg catcctttcg actacttttc
    22321 tttgaacatc gatgcttttt tgattgtcgc tgatacagga atcaaaggac aaacaagaga
    22381 agccgtcaaa gatgtcgctc acctctttga aacccagcct catgaaactg gacaaatgat
    22441 ccaaaaatta ggatacttga cgaagcaagc aaaacaagca atcattgaaa attcaccaga
    22501 aacgttggca cagacaatgg atgaatcaca atcacttctg gaaaagctga caatcagcaa
    22561 tgattttctt aatctattga tccaaacagc aaaagatacc ggggcattgg gtgccaaatt
    22621 aactggcggt ggacgcggtg gctgtatgat tgcattagca caaacaaaaa caaaagccca
    22681 agaaatcagt caagcacttg aagatgcggg tgctgctgaa acttggatac aaggattagg
    22741 agtacatacc tatgtttaaa ggcaaagcac gcgcatatac caacattgct ctaatcaaat
    22801 attggggtaa gaaaaatgaa gaactcatcc ttccaatgaa caacagcctt tcgttaacat
    22861 tggatgcatt ttatacagag acagaagtca tcttttctga tagctatatg gtagatgaat
    22921 tttatctaga tggcaccttg caagacgaaa aagcaacaaa aaaagtcagt cagtttcttg
    22981 acctttttcg taaagaagcc ggcctctcac taaaagcttc agtaatcagt cagaatttcg
    23041 ttcctaccgc agctggatta gcctcctctg ccagcgggct agctgcttta gcaggcgctt
    23101 gcaatactgc tcttaagctt ggattagatg atctctctct ttcaagattt gctcgacgcg
    23161 ggtctggttc agcttgccga agtattttcg gtggtttcgt cgaatgggaa aaaggccatg
    23221 acgacttaag ttcttacgct aagccagtcc cttccgattc tttcgaagac gatttagcaa
    23281 tggttttcgt tttgatcaac gaccagaaaa aagaagtgtc cagcagaaat gggatgcgtc
    23341 ggacagtcga aacatccagt ttttatcaag gctggttaga ttccgttgaa ggggatctat
    23401 atcaattgaa acaagcaatc aaaacaaaag atttccaact tctcggagaa acgatggaaa
    23461 gaaacggact aaaaatgcat ggaacgactt tagctgccca gcctccattc acttactggt
    23521 ctcctgacag cttaaaagcg atggatgcgg tgcgacaatt gagaaagcaa ggcattccat
    23581 gctactttac gatggatgct ggccctaatg tcaaagtttt agtggaaaac agccatttat
    23641 ctgaggtaca agaaacattt accaaattat ttagcaaaga acaagtaatt actgcacatg
    23701 ctggtccagg aattgcgatt attgaataaa gggagatttt tatgattgaa gtatctgcac
    23761 caggcaaact ctatattgcc ggagaatatg cagttgttga aacaggccat ccagcagtta
    23821 tcgctgcagt cgatcaattc gtgacagtca ctgtagaatc tgcacgaaaa gtcggaagta
    23881 tccaatctgc acaatatagt gggatgcctg tacgttggac aagacgcaac ggagaattag
    23941 ttttagatat tcgggaaaat ccttttcatt atatccttgc tgctattcgc ttgactgaaa
    24001 agtatgcaca agaaaaaaac attcttttat ccttttatga tctgaaagta acaagtgagt
    24061 tagacagttc aaatggccgg aaatatggat tgggttctag cggtgccgtg accgttgcaa
    24121 cggtcaaagc cttgaatgtt ttttacgcgt tgaatttatc tcagttggag attttcaaga
    24181 ttgcagcact agccaattta gcagttcaag ataatggttc ctgcggcgac atcgctgcta
    24241 gctgttatgg tggctggatc gctttctcaa ccttcgacca tccttggctc caagaacaag
    24301 aaactcagca ttctatcagt gagttacttg ccctggattg gccaggtcta tccattgagc
    24361 cattgattgc tcctgaagat ttacgtttat tgattggttg gacgggtagc cctgcctcta
    24421 cttctgattt ggtcgatcaa gttcaccgtt cgagagaaga taaaatggtg gcttatcagc
    24481 ttttcttaaa aaatagtaca gaatgtgtca acgaaatgat caaagggttt aaagaaaata
    24541 atgtaacgtt gatccaacag atgattcgaa aaaaccgaca attactgcat gatttatctg
    24601 caatcactgg ggtcgtcatc gaaacgcctg ctttgaacaa attgtgtaat ttagctgaac
    24661 agtatgaagg agccgcaaaa tcttctggtg caggtggggg cgattgcgga atcgtaattg
    24721 ttgaccagaa atctggcatt cttcctttaa tgagtgcatg ggaaaaagca gaaatcactc
    24781 cactgccgtt acatgtctat agcgatcaaa gaaaggaaaa ccgatgaatc gaaaagacga
    24841 acatgtttca ctagctaaag cctttcatga taaacaaaaa aacgaatttg acttcgtacg
    24901 gatcatccat aaccctttgc cgcaaatagc agtttctgat gtcgatctaa gtacacaggc
    24961 agttgggttt acactaagca gcccatttta tatcaatgcg atgactggcg gaagcgaaaa
    25021 aacaaaaaaa atcaaccaag atcttgcaat cgtcgcaaga gaagcagatt tgatgattgc
    25081 cactggttca gtcagcgctg ccttgaaagt cccttcttta gccgatactt atacgattat
    25141 gcgacaagaa tatcctcacg ggaaaatcat tgccaacatc ggtgcaggga cttctgtcga
    25201 aagagccaaa gaagctatcc gattgtttca cgcagatgcc ttacagattc atttgaatgc
    25261 acctcaagag ttggttatgc ctgagggaga ccgtgatttt accaattgga aagtacttat
    25321 tcaagaaact caaacagcca ttgacgtccc cctcatcgta aaagaagtcg gttttggcat
    25381 gacaagagaa acgctcaatg atctagctgc tttaggagtt catacagttg atatcagcgg
    25441 tcgaagcgga acaagcttca cccagatcga aaacgcccgt cgctccaagc gggaactgag
    25501 ttatttagct gactgggggc aatcgacagt ctcttcattg cttgaagcaa atgaagcaga
    25561 cacttctatg gaaatcctag cctccggagg tatccgcaat gcctatgaca tatttaaagc
    25621 cctttgtctc ggcgcaaatg ccgtgggtac ttcaggaacc gtactgacgc atctgatgaa
    25681 tcacggcgta gaagaaacta ttatactgat gaagcaatgg caagaagagc ttcgtctgct
    25741 ttatactatg gtcggcgcaa cgaataccgc ggccctacac caacaatctc tgatcttttc
    25801 cggaccagtg aaggattggt gcgaagcaag agggatcgac ttagtgaagt atggaagacg
    25861 cacagaaaag agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta
    25921 caaacggcgg aagtaaaagc aactccttcg gaaataagct gaaattcaca aaaatttgaa
    25981 aagcaatttt cgtgaattcc ttcttatttc ttggagttaa atgcttctgt cccagcctct
    26041 tttttcgaat aaatgatgtt taatcagctg tccttcggta ttcgttcaat ccgctgattt
    26101 cacaacctct ccactaaaca gtgtactaaa gctcttttaa ggttgttttc cgatataggc
    26161 aagtatgcct ccgtccacat acaagacatg gccgttaacg aaatcagatg cgctagaagc
    26221 caagaagaca gatggtccag ccaaatcgat tggctcgccc cagcgtgctg ctggcgtacg
    26281 tccaacgata aattgatcga atggatgacg ttcaccgttt tcttgtgttt cgcgtaatgg
    26341 agcagtttgc ggtgtagcaa tataacctgg tccaattcca ttacattgga tattgtattg
    26401 accgtattca gaagcgatgt ttttcgtcag catttttaat ccgccttttg ccgcagcata
    26461 agcactgacc gtttcgcgtc ctaattcact catcatggag cagatattga tgattttacc
    26521 gccgcctttt tcgatcatat ccggaataac tgcttttgaa acgatgaatg gggcatttaa
    26581 atccacgtcg attacttggc ggaagtctgc cgcatccatt tcgatcatcg gtgtccgttt
    26641 gatgatccct gcattgttga ctagaatatc aactgaacct acatcttctt tgatctgttg
    26701 aaccatcgct tgaaccgctt cttcatcggt cacatcgcag acataacctt ttgcatcgat
    26761 gcctgcttct ttataatgcg ctataccttc atcaactgat tcttgattca agttattaaa
    26821 tacgattttt gctcctgctg tagctaaaga gcgtgcaatc tcaaatccaa taccatagac
    26881 agcaccggtg actaatgcta cttttccatc taaacgaaac atatccatac taaattccat
    26941 cattttctct cccttatgct tattttaatt gatccatttg caccatatcc atgtctgtat
    27001 aggtgatatt ttctccgcac attgcccaga tgaatgagta attgcttgta cctacacctg
    27061 aatggatcga ccagcttggc gaaataatgg cttgttcatt gtctacaact aaatgttttg
    27121 tttcatctgg tttgcccatc atgtggaaca cacgtgtatc ttcattggca taatcaaagt
    27181 agacataagc ttccatacga cgttcatgtg tatgacaagg catcgtattc caagcgcttc
    27241 ctggttctaa aatcgtataa cccatttgta attgacagct ttcgcataca tttggatgga
    27301 tgtattggta gattttacgt tcattcagtg tcaggccttc accagtctcc attggtttta
    27361 cttggtcgat actgattttt acatttggat atttatgatg agctggaaca gaactaatat
    27421 agaatttagc tgggttttca gcatcttgag aagaaaatac aacatgtcgt gtttcttttc
    27481 cgatatagta tccgtcttgt tttttcattt cttctttttg cccatcgatc tcgatgaatc
    27541 ctggtccacc gatattgatc acacctagtt cacgacgctc taagaagtaa tcaacaccta
    27601 gttctttgtc taatgtgatt tctaattctt tttcagtagg tgtcactcca ccaaagatca
    27661 ttcgatcgtt gtgcgtataa gtcaaactga ttttccctgg ttcaaatacc ttttctacta
    27721 aaaattcttt tctcaattgt tccgttgaat aatgacggat atcttctgga ctgtgtgtat
    27781 aacgtgtttc catttcttgc attttcttct actccttcta tcgaatgatt tttccagagc
    27841 cgcatgctaa aaattgtgcg acttcttctt gactaaattg gttgcagtcc ccatggatcg
    27901 tatgcttcaa ggcagaagct gccgtagcaa aatcaatgat ttcttgcgga gacatattgg
    27961 ataaaatccc atggagcacg ccacctgcaa aagcatctcc gccacctact cgatccacga
    28021 ttggggtgat tctatggact tgggattcca catattcatg gttcatccac aatgtcccct
    28081 tcaattcatt ttcacttgct gaatgaacgg tacgcttggt cgaataaaac acctgaatat
    28141 tcgggaactt ttcctgcatt ttttgataat aataaattag aggttgttct tctgcttctg
    28201 gcgctttctc gatacctaac aaataaagag catccatttt tccagctgag cagatatcta
    28261 ctaaaggtaa aagctgatgg attacttcgc tggcttcttg ctgtgtccat aattttccac
    28321 gatagttgat atcgaagctg atcaggcagc cagctttttt tgcagcttct atcacctgtt
    28381 tcgtcatttt ttgccatttt ttagacaaag ctggggtgat tcctgaaaca tgaaatatat
    28441 ctattccttg gaataactcc tctagcgacc attccaaatg atccatttca gcaaaacttg
    28501 atccggcacg atcatagatc actgaggcgg cgcgttcgcc actaccagtt tccatataat
    28561 aagtacctag tcttgatcca ccagataata cctgtttcgt atctactcca taacattgca
    28621 agtgcttttt gactgctttt cccaatgcgt tatcaggtac ttttgtagca aaaatcgctt
    28681 catgtccgta attagctaaa gaaattgcta cgtttgcttc ccctccgcca taatgggcag
    28741 cgaatcgttc acttgaatcg atacgggttc cctgctctgt ggacaatcgc aacatgattt
    28801 ctccgagtgt cactactttt cccataagca gctacctctt gatttctttc atttttgctg
    28861 catactgttg cgcgacttcc gttactttgt caaaatctcc tgtagctgcg ggtgctaaaa
    28921 ggttcccacc tactccgact gttacgacac cagcatcgaa ccactctttc atattgtcca
    28981 gactcacacc gccagttggc atgatattga cttgaggcat cggcgccttg aaggcagaaa
    29041 tgatacttgg tccataagcg cttccaggaa atagtttgac gatatctacc ccgcttttca
    29101 gcgctgtttt gatctcggta atagtcatac atcctggtaa gtaaggaatt tgatacagat
    29161 tgcacatctc tgccgtttct tgatcaaagg aagggctaac aatatactct gcgccagcta
    29221 agatagccaa gcgagctgtg acagcgtcta atactgtgcc tgcgccaatc actatttctg
    29281 gttggtcttt gtagaatgac aaaagttctt tgattacttg atctgcttga gggactgtaa
    29341 aagtcaactc aataccagtt agaccacctt tgatgattgc gtggcaagca ttcaaagctt
    29401 cttctttgct ttttccgcgt accaccgcaa tcactccggc gtttttcaat cgagataaaa
    29461 tatcaatttt tttcatcttc tccacctatt tcctatttag aaattttatt ttataacttg
    29521 gaaatctata cccatattat acggcagaaa agaaaaattg caaacgcttt tttcattatt
    29581 tttgaattct ttgctcgatt tcgctttttg tttgcttgag ggcactgatt atttgttctt
    29641 ttgtctcatc tgttaaacga tatttcggca tacttacact aaatgcacca atgatttgtt
    29701 cgtttttcac gattgaggct cctatacaaa aaatatcacg ttcgatttct tcatcgtcaa
    29761 atgcgatgtg ggtttctttt accgttttga tttccttttt caaccgtaat gcattggtga
    29821 tcgtatattc tgtgtaaggg atcaacggat gcttttcaag ataatcagtg tactgctctt
    29881 cactgaattc tgctaatacg gctttgccca tcgcagaatt gtataatggt cgggtgattc
    29941 cgatttttga agacatgcgg atcgtttgat gttttggatc tagtttgttc acgtacaaga
    30001 tctcattgtt gtccaatacc cctaagtgga tagtctcatc gatcttttgc tgcagctgtt
    30061 ctaaaaacgg taaagtcaac tctaccaaat cgatttgttc aatgttttta ttcgcgtagc
    30121 gaataagctt tgcacctaaa cgatagtttt tctctgaatt tttatttacg tagccgatca
    30181 tcaacaaagt atctagtatt ttcaagactg tagaagaggt cattcccaca ccctttgcga
    30241 tcgtctgcaa agagacatct tggttttccg ctaaatagtc tagtatttta gaggctttga
    30301 tcaatacagt tccataaggc tttttatttt ccatataata ttctcctatt tctttataag
    30361 aaaaattata gcggaaatac catcaattta aaagagatat ccagatataa actaccattt
    30421 ctctttacag gcaatttaat gttgaagatc cgcttcgttt ttacatcaaa ctttgatata
    30481 aagcaatgat ttcttctact gtcgtttctc ttggatttcc tggtgtgcat acatctcgca
    30541 aagcatcttc tgcaattgct ggaatatctg cttcttttac acctaattca gaaatggttt
    30601 ctgggattcc aaccgctttg ctcaaccgat cgatctcacc acaagccgct tctcttacat
    30661 cttctaaaga catttcagct gctcctttaa tccctagaac aagagcgatc tcacggtact
    30721 tttctccagt atattctttg ttatatttca tgacagttgg caaaagtgct gcacacgcta
    30781 cgccatgagg aatgttgtac catgcactta acgggtgagc catcccgtgt accagtccta
    30841 aaccgacatt tgagaagccc attcccgcaa tatactgtcc taatgccatt ttttctcgcc
    30901 cattttgatc gccatctaca gaagcttcca aagaatggcc gatgatttcg attgctttta
    30961 aatgcagcat atcagtcatt tcccaagcgc cttttgtgat aaacccttca atagcatgcg
    31021 tcatagcatc catacctgtt gatgcagcca attttttcgg cattcccatc atcatatcgc
    31081 tgtcgatgaa cgcgacgatt gggatatcat gaggatcaac acaaacaaat tttcggtgat
    31141 ttacttcatc tgtgatgacg tagttgatcg ttacttctgc tgctgttcca gaagtcgttg
    31201 gtatagctaa tataggtaaa catggatttt tcgtatcagc aacaccttct aaactaatga
    31261 cgtctgaaaa ctctggattc gtcaaaataa tcccaatggc ttttgccgta tcgattggcg
    31321 aacctccacc gattgcgatc aaacagtctg cctctgcctc tttaacaaaa gccactccat
    31381 cttttacatt ttggatcgtt ggattaggta cgatcccgtc gtataaagca taagcgattg
    31441 ctgctttatc tagaagttct gttacttttg ttgctatacc gtgctcgatc aatcctttgt
    31501 cagtaatgac agctgctttg ccgaatcctc gctgctgaaa ttcagggacg atcgactcaa
    31561 tcgctccttt tccaaaatac gatgtttcat ttaaaatcat tcgattactc attttctatt
    31621 cctcctaatt tgtattattt ttcacaataa aaacgaaaga accccaagca accggttgcc
    31681 cagttgcttg ttgctacagt tcaaagactg gcatcaattc ccaactgact ggagaggcat
    31741 ctggatttgt ctccatgata tcttccatgt acttccacca tttttgattg atagatgtat
    31801 ttgccatttt ttcccataac ttttcatctt cgatcactaa gtaaccaaat aacaaacttg
    31861 tactcggatc aagatagatc gaatagtcga tgaccccgtg ttcacgaagt gctgtacgca
    31921 tttctggcca aagttcatca tgtctttttt tgtattcttc ttgtttttct gggtaaactt
    31981 tcatgcaaaa agcttttttc accatgtcag acacctgctt tcgtatgaac ttcctccaaa
    32041 taacctgctt ttggagtgac accaaacgca tctgctaaat gccacaggtt ttcgtccgtg
    32101 attgtttgca agattggtcc ttgcgctttg acgtacgtat agacttctgc tgccttttct
    32161 gctgtctcga tcaaaccaaa gacttcatcc atgtcttttc ctgacccgta gattccatgt
    32221 tgtggccata aaaccaatcg agtttctttc attttttcag ctgttgcttc cccaatctca
    32281 tttgttcccg gaaccatcca cggaatgatg gaaattcctt ctggaaaaac aactaagcat
    32341 tccgtacaca tttgccatag cgtacgacta aaggaacgtt cgtctaattc atgcgtaaaa
    32401 ctcatcgcta atagatgact agcatggcaa tgcataacga tccgattatc tgggtctact
    32461 tctaaacggg cgatatgact catgaaatga cttggcaact cgcttgtagg aaggcattcg
    32521 ttttccagcc cccacaaaag ttccagtgtt ttgccatctt cagcaactcg aacgattcca
    32581 agattctcgg caggttcgct cgctacattt ttaaaatatc ttcctgaacc agttacaata
    32641 aaatagcatc ctgctaaacg gctggcatca aaaatcatcg agatgcggcg gatcactttt
    32701 tcaggatcca agaacggtgt gatctcttct tcttttagta aataagaaat attcccgcca
    32761 tttctttcat cccatcccaa gcgataaaga ttcgacgtcg tttcgatcat ttctttcaca
    32821 taaggcgctt gtaaaatatc tatttttttc aatatagcca cactcctatt ttcttaattc
    32881 caacacgtct ttttgatatt cctggacttc ttccagccaa tccaaaccaa ctggaacttg
    32941 atttttgtaa cagaaataat tccatacatc ggcatacggg aaatctttca attcttccgt
    33001 ataagccatt cttgaagtaa agtcaaaagc cagctccatt tctttcaatc gctcaactgg
    33061 ttccagcata gctttcagca gtgctttttg tgtatttctc gtaccgatga cccaagcagc
    33121 gatacggttg atcgttgcat caaagaaatc cagaccgata tttgtttttt ccaacaattc
    33181 gttacggact aattctttag cgatttcctg caattcatca tccatcaaaa ccacatggtc
    33241 tgaatcccaa cgcactggac gggaaacatg caacatgatt cctttgctga ataaagctaa
    33301 tgaagataat ttattggaaa tcacttctgt tggatgaaaa tgtccagcat ctagacaaac
    33361 aagtttgtca cgagtcaacc cgtaacccat ataaaattca tgggaaccga ctgtataagc
    33421 ttcagcgcct aaaccaaata gtttgctttc tactgcatct tgtacatacc gttcatctaa
    33481 ctcttctgta aaaatttcat cgagtgattc cattaaacgt tcccgtgggg taaaacgatc
    33541 aatcggatta tctttcatcc catcaggtac ccaaaagtta ttgatacttg tttgcccagt
    33601 ttctttccca aagtactccg cgattttgcg gcttcttttc ccgtgttcga tccagtattc
    33661 acgaacttct ttatctggat gagccaatgt aaagccgtct ttcatcattg gatgcgaaaa
    33721 gaaagtcgga ttgaagtcaa gaccgatttc ttcttttttt gcccactcta cccatttttc
    33781 aaaatgtttc ggctcaattt catttagatc gacagattct tctgtatcca aatagatagc
    33841 atgaaggttc aatttgtgtt tgcccggtat caacgaataa gccttctcca gatcttgtct
    33901 aagctcttca ggtgttcgtg cggctcctgg aaaattccct gtcgccatga ttccaccggt
    33961 caattcgcca tccggtgtca agaaaccttt gacatcatct ccttgccagc aatgcataga
    34021 aattttgatg tcctgtatct tttctagtac agcatctgta tctacaccga tagttgcata
    34081 tttttctttt gcttgttcgt aatttctttc aatcgtgttc atacgattac tcctttgatt
    34141 ttattcacgt accattccat cgtgttttgc ttattttcat ctgggtaaaa agtttcacat
    34201 ggaaacgact gtttgattac atttcttgct tgttctatat tcgaaaactg acctgtactg
    34261 agcatttgca tggcaacatt cccgattgct gtggcttcac taggtcctgc ttctacaatg
    34321 attccggcat aatctgctgt caattgattc agtagacgat tattcgatcc gccccctacg
    34381 atgtgcagct tttccaattt cgttccagtt aagtgttcta ctttgatcag ctcttgtgcg
    34441 taacaaagag caagattatc atacacacaa cgagcgatag ctcccgatga gacagggact
    34501 ggctgctctg tttcaaaaca gtattgctga atctcttcta tcatatttgg gggattcaaa
    34561 aatcgagggt cattgatttc catcacttgc tgcagcggtt tttcttttgc agcaagctct
    34621 gccaattccg cataactgta ctcgtactct tgcattcggg caacttcctg gatcaaccac
    34681 atccccatga tgtttttcaa aaaacgcacc gtgttatggg caccccattc attcgtataa
    34741 ttttcagaaa aagcattgcg agaaacattg gcgatctttg tttcaatccc taaaagcgac
    34801 catgtcccac tgctgatata accccaacgt tctccttgac ctggcgttcc taatacagct
    34861 gacgccgtat catgacttgc tactgtgata aaggtcacat ctggcaaatc atattttgaa
    34921 aattgttctt tttgcagatc tcctagtatc gttcccggct ctgtcaatgg tggaaataat
    34981 tccttcgaga caccgatttt ttcaagaagt tctatttccc attcttttgt ccctgcattc
    35041 agcagctgca tagtagatgc attagttttc tccgtcacca tgttaccagt aaagacatac
    35101 cctaaataat caggtatcag taacaattta tgtgcttttg ccaaattttc tttttcttca
    35161 gcaaacaatt ggaacaaggt attgaaaggc tggatctgaa tccctgtctg ctcatacaac
    35221 ttatctagag aatagatttc agaaaactgt tctactgctc cattggtacg cttgtcccga
    35281 taagcaatcg gatcatttat ccgatcccct tgttcatcaa tcagacagta atcgactgcc
    35341 catgtatcga tccccgcaaa aaggcgatca atccctgtct gctttaattt ttcaaatcca
    35401 atcaaaatct ctttgataag ataatcgatc ttccagcgat cgtgaccgtc tttgttccga
    35461 aagccgtttt tgaaccggtg tacttcttcc aagatcaaag aaccttttgc atccctcgta
    35521 cttttcatta gtcgtccgct tgatgcaccg atatcgatgg caacaaatgt tggattcatt
    35581 tctccacctc ttttacttta ttgttgatta gcactttatt aataaagcgt tatcatttat
    35641 tgacaatgct atcataatac agaatcttat attttgcttc acactatttt ggtatataat
    35701 tgcattatct tgacaagttg ggagtgttta catggattac tgggaaaaag ccaaccactc
    35761 atggtcggaa gactcaaaaa gagtgatctt gacgcctaca caaagaagca ggaatttatt
    35821 tttttatatc caagaaatcg gttacttcaa agcaccaatc ccttactata ctgaacgagc
    35881 acatttacct tcttacttga taaagtttac tttgtctggc aaaggttcgc ttacatataa
    35941 tgataatcag caacagctaa aagctggaga cttatttttt attgactgcc aagaatatca
    36001 gcgttatcaa acgatcagcg aagaaccatg ggaaatggat tggatccatt tgaatggtca
    36061 gaacgtccaa tcattttatc aggagttcac aaaagacggc cataacacct tccattcaac
    36121 aggagatcca tcagaaaaca agatccacca tttgatcaca gaattgatcc acatgcaaca
    36181 aggcacgaat gcccgtaccg atttccagtc ctctgtagct atccacgagt tgctgaatga
    36241 actgattttg caaaagtatc agctagattt cgaagaagag gatattcccg cctacgttta
    36301 caaactgaag caatacttag acgaacattt caaagaaacg attacacttg atcaattaga
    36361 acaacaattc ttattgaata aatatcagct gagcaaagat ttttccaaat ttatcggttc
    36421 tccaccaatc gattatttga tcagcaaaaa actttcttac gctaaagacc ttcttcggta
    36481 tacagaattt acggttcgaa tgatttccga agaaataggg attgagaatt ttgcttactt
    36541 tagccgcctg ttcaaagcaa aaacaggact atcgccgaga gactttcgta aattcagctg
    36601 attcatataa tatgtacgtc attttttcaa aatattttga aatatataga taaaaataaa
    36661 ataaccgcag tttctgcttc tatgtaaaca acagcagcta ctgcggttat tttttagtga
    36721 tcattctcat tgttcatctt caaaatgttc ataatgaacc aactgtttct gtgtatcacg
    36781 tttcaaaaat tctttaggcg ttatgccgaa ctctctcttg aatgctttca gaaaatgcgg
    36841 ataagaagaa aaaccacttt tactatatac agcactagag ctgcggtatt ctcgcaacaa
    36901 gtgcttggca tagatcagct ttttcttcat tacatactga tgaaacgtaa atccagtgta
    36961 ctttttaaat tctcgtgtga tatggtattt gctgacaaaa aactgctttt ccatttcctc
    37021 taaagaaagc ggatgagata aattttttga gatatattgt aacatttgtt ccacacgctc
    37081 attaggaact acagcattct gttcttgcgc actctcttct ttttgtacaa cttgattgag
    37141 aaaaatcaag tattctacca gagcttgttc atattttatg tcttcaccgt aaattttttt
    37201 atcaggagga tggtcgataa atgataattt ttgcttcaat acttcctgtt ctatttgcaa
    37261 tacacgactc ctcttctctc ccattggttg aaaacaagcc gatagattag accatggcgt
    37321 ggaacgactt tctagaaaag aaggggtgac aaagatatag acacgctcga atacatctga
    37381 agattggcgg acgatacgat gcaaatcatt ggaatggatg agcagcacac ttcctgcttt
    37441 gatcgtaaat tgtcgtccgt tcaaataaaa agtcgcttct ccctttaatg tagcatggat
    37501 ctcatagaaa tcatgatgat gatagatcgt tttattttgg ctgacgacat ctttgacatg
    37561 atagatttca tactgatcag aaaccatcgt attgacttgt tcaccgctga ttttcttttg
    37621 gagcatgtgc cgcacctcct tttgttcact tatgcacaat tttattatac cacgtttttt
    37681 gtaatcaaaa agagctgctt ttatatactc ttataaaaaa gaagagacgt ggcatcttct
    37741 agccccgccc cctccattct aaatattagt taaccaacgt cttctttaca ttattcaaga
    37801 agacttcttc cataacgaat cccatcatct tttgtttctt caagaaccac atacaggtac
    37861 ggacgattct tcatgatgat ttctttgatt tttgtgtact cgatcacacc gtctcccaaa
    37921 tttaccggca cgattttttc ctgttcgaca cgaaaatctt tcaaatgaac cgcacatatc
    37981 ttttcaccaa aacgttcaaa agcttcttct accaattgga cttgttcttg ataatcacta
    38041 cttgtgatca aattggtcgg atctaaaatg attcctagat agtccgaatc tactgcttgg
    38101 atcagctgct ctacccttgc taaagaatac accggatgat tcaaacctgg ttctatcccc
    38161 accatcattt ggtatttttc tccagctttt accaagcgac ggataacgga cacagcttca
    38221 gcaaatgctt catctgtgaa attttcttcc gtatattgga tttccggcaa aacacatcca
    38281 gtttccgaag caaccatcga cgcaccaaag gaagaagcat agcgaagata ctgctcgaac
    38341 tttgtcagca actcttgtcg tatcgttaaa tctggatgaa tcatattgat atagcaactt
    38401 aaaattccta cggtcacttc ttgcttttct aaaactcgtt tgacataatt tcccatccca
    38461 gaattgatct catttgcgcc agaaggtatt tcaggaaacg aaagacctaa ggcgagctgc
    38521 agtgtatgaa tcccttgttc ttttgttttt tctgcaagat cttctatcgt ttggacttcg
    38581 gaaagatcat gtcctctaat tgtaatgttc aacataacta ttctcctaac tcagcatatt
    38641 gggtagccac atgacgattt gcgggaagta agtaatcaaa aacaagacga ctaagataac
    38701 cccataaaaa ggaagaagcg gtttcagcat tgcctctgct tttacgcctc ctacacttgc
    38761 accgacatat agtcctgtac ctactggcgg cgtgatggag cctacacaca gattcatgat
    38821 tgaaaacaac ccgtaatgta caggatcaac ccctacactt gtgacgattg gtaaaaatat
    38881 tggtgtaaaa atcaagatag caggcgccac atccataaac atacccacca gtaataacac
    38941 aagattgact aataacagaa taataaattt attatccgtt acgcccataa tcaacgaact
    39001 aattgcctga ggaataccgg taaacgccat ggcgaaagac atcatggaag aagtagccaa
    39061 taagaacatg atcgtccctg acattgctac tgattgaaac aacatattag gtatatcttt
    39121 tagttttacc gttttatagt aaaacatagc aatcaacagg gagtaaatga cagctatcgc
    39181 tgaagcttct actgctgtaa atatccccgt caagatacca ccgataatga tgacaatcaa
    39241 tagaaggcta ggaatcgcct cttttattat ttttccagca tgagccatct gtcctttttc
    39301 gacaacaggg tatttattct ttttagcaac gatgaatgct actagcatga ttcctagcgc
    39361 ccacaaagcg cctacgagat aacctcccat aaacaaagca gagatcgaag caccaccagc
    39421 aacaagtgaa tacatgataa aagcagtact tggaggaatg accatacctg tcggagctga
    39481 cgcgatattg accgctgtcg caaacttccg gtcatatcct tcttccactt gctgagggat
    39541 caacactccg ccaatcgcgg tagaagcggc aatggccgag ctagagatgg aaccaaataa
    39601 agcattccct aacacattcg tatgagccaa agcccccggc acgcgcccga cgaacaacat
    39661 cgcaaaatcc actagtttct tagctatccc tccattattc atgataatgc ccgagagaac
    39721 gaaaaacgga atagcgatca gcgaaaaact attgatactt cccaccattt tttgagctga
    39781 actaaaagca gaaacatcaa acggtataac taacaataaa gtcatcatcg atgagaatgc
    39841 aatacttata gcaatcggca tccctaatac aagcaacaca acaaatacaa aaaataacac
    39901 taatccggct tctattgcca ttttattcct ccatttttat attttttctt gaattgctgg
    39961 cttgttgctt aatgtatcga ttagattgat caggctatag ataatgatga gtacccccga
    40021 tacaggtact gacagataaa catatcccat aggaatactt aaagaaggcg agatctgccc
    40081 cattgtcaat gtgacagcat tccatccgcc atacaccatg atcatcgcag caaataccag
    40141 aaataaactt tgaacaacaa cttctaaaat tttacttttt ttgccagtta atttttcact
    40201 taaaaccgtt acggctaaat gtgctttttg tcccacaaca tacgcggaag acaacatggc
    40261 aaaccagaca agaccgaatc gaacaagctc ttccgtgacc gtatttggat ttcctaaaac
    40321 cgttctggaa aatacttgcc ataaaacaac agcgaccatc ccaacaagca aaacagctcc
    40381 caggatctct aataccttgt ttaaaatcat tttcatcaca gctacgctcc ttgctcttgg
    40441 atcttttgat aaaggtcttt gtaggtagga tcgtttttga atatatcatg aagtggggca
    40501 actgcctctc gaaacggtgt attatctaca tcattgaatt ggactccatg ttcttcttgt
    40561 gctaaagctt tttcttcttc aattgctttt gcaaaagctt caatttcaaa aaccgttgat
    40621 tctttcgctg cttcttcaat ggctttttcc tgctcatcag ttagctgttc tttgatggca
    40681 tcattcatga tgatgatatc tggcacacgt gtatgctcat cataggaata gtatttagcc
    40741 acaccaccat gtccagctgt atacaagaca aattcattgt tttctgatcc gttgatcaaa
    40801 ttggattgaa gagacgtgta cacttcatca cttcccatag gtacgggcga accgcctaaa
    40861 agctctacca ttttgatagc ggtttcgctt tgcatcacac ggatcttctt tcccttcaaa
    40921 tcttccggcg tatggatcgg accgtctacc atataaaagc tgcgctgacc agaatcataa
    40981 taggtcaatc cggtaaatcc taaatttttg gtcgattggt agattggctc cattatttct
    41041 tcattatcca tcaccttaaa gaaatgttct tcatcattga atagataagg aactgaaaaa
    41101 atcgaataat ctttagagaa actttccaac gctgaggcac ttacttttgt gaaatctact
    41161 gctcctgact gtgtcaattc gatcagttca cgttctccac ccagttgtcc atctgggaaa
    41221 tactggatct gtacggaacc atctgttttt tcttttacta aacgcccaaa ttcattcatt
    41281 gcatcaatta ctggctggct gttgcttgca taagcaaagc gcaaggtaac tatctcattt
    41341 acatctgcat ctgcgacagt tgccacacta gaattatttc cgcagccgct tagacctagc
    41401 agacctaggc taagcgaact tgctgcaaac agcagtgatg tttttttcat atgggtttcc
    41461 tttcttttaa caataagaga cgagcaattc tgtcaaacaa agcaccgtta acgactgtcc
    41521 ataaggcatt gctgtgattc cgatattccg ataaaaatct aaactgtccc ccattcctgt
    41581 cccgattgaa acgttttgaa cttctccttt ttcatcgatt tgttcaagca atccttggat
    41641 agcacgataa gcgacttctt tatattcttg tggtaaataa cgtttatgga ccgctttcaa
    41701 aataccgtaa gcaaatcctg cagttgcaga agattctacg taagaagaag gatcatccaa
    41761 caacgtatgc cataaaccgc tttcagactg ataagttttt aatgcacgca cttgtgcttc
    41821 aagtgtttcg atcaataatt tgcgcaatgc atcttctttc gataattcta agatttcaat
    41881 gatctctgga atagcaatcg tcaaccagca gtttccacga gcccaaaatg cttcggcata
    41941 gttatgattt ccttcaaacg tccagccgtg ataccacaat cctgttcgtt tatccatcaa
    42001 gtatttgata tggatcataa actggtaacg agcttcttct aaatattctg ggcgattcaa
    42061 cagtttcccg atttttgcca aaggaagcac tgtcatcatc aatgtatcgt cccacaactg
    42121 attcttattt tccggtccat atgtggcatg ctgtaacccg tcttcatttg tccgaggcat
    42181 gtcattcatg acccattctg cccattgttc taaataaggc aaatagcgtg aatctttcgt
    42241 gtcttcatac aagtaagcca tagtcaatag cggtgccatt gtattgacgt ttttgggcgg
    42301 agcgccttct tccatacgat cctcaaacca ttcattgacc acttgataag cgcgaggatt
    42361 ttttgtcatc tggtaatttt tataaatacc atatagaccg acaccttgtg gccaattcca
    42421 cactgtccag cttttgtcat ctactttcag tccatcaaag tccaacaaaa attcaccatt
    42481 atcgtctttg atcgttgtca ggttttcaac gagcaggtca attttttctt tcactaattc
    42541 tttaggtaca aaaatctctt ctttaataat catctttacg ccaccttttt aaacgctttc
    42601 attttatatc cttaatatag cagtaatacc gtccactata aatatcgctt tttgaacaaa
    42661 aactgtctaa aattgaccta aatgttaaat aacaaaagta actttcagtt acttggaaat
    42721 taaaaaaaga acttggagaa acaacgtttt ccaagttctt tttcatctat tttcttatct
    42781 tttttctacg ctttcttttg cttatccgtt gtaagcatca atgatgatct gtttcaattc
    42841 agagatcaat ggttctttcg gattagctgt cgtacattgg tcttcgtaag ctaattcagc
    42901 catacggtct acggttgtat ctagtgtttc ttgtgtgact ccttgagctt ttagactcat
    42961 gttgatgccg acagattttc ctaattcata aacagccgtt gctaaagctt cgactaattc
    43021 ctctgttgtt tcgcctttca gacctaagaa ttttgcgata tctgcgtaat ctgtatctgc
    43081 acggaaatag tcatatttag ggaacatcgc atgtttttgt ggatcttttg cattatagcg
    43141 gataatatgc ggtaaaagaa tcgcatttgt ccgtccatga gggatcccgt attccccgcc
    43201 gattttatgt gcgactgagt gacaaatacc taggaatgcg ttagcaaacg ccataccagc
    43261 cattgtagaa gcgttgtgca ttttttcacg tgattccata tcaggtgttt ttactgattt
    43321 ttctaaatag tcaaagacta acttgattgc ttgtaggctc aatccacgtg tataatctga
    43381 agccatgact gaaacatagg attcgattgc atgtgttaac acatccatcc cggtatctgc
    43441 tgtgacagat gctggaactg acatgacgaa ttgaggatcg acgattgcga catctggcgt
    43501 caatgcataa tctgctaacg gatatttcac atgtgtttca ctgtcagtga tgaccgcaaa
    43561 tggcgttact tcagaaccag tccctgatgt tgtcgggata catacgaatt gtgttttttc
    43621 tggtttgtcg atcttatatg tccgtttacg gatatccaag aatttttgtt ttgcaccaaa
    43681 gaaagatgtg tctgggtgtt catagaacat ccacattccc ttagctgcgt ccattgcaga
    43741 accgcctcca agagcgatta ctgtatctgg cttgaagtct gccatcagtt tcgttcctgc
    43801 gtatacggta tttgtcgatg ggttcggttc aacatctgag aagacttcga tcttcacatc
    43861 atttttacgt cgtgccaata cttcacgaac tgtatcgcag taaccgaatt ggaccatacc
    43921 agggtcacaa acgatcatga cacgttcaac gttttccatt ttctctaagt acaatagaga
    43981 gttcttttca aagaagattt ttggcggtaa tttgaaccat tgcatgttat ttctccgttt
    44041 cgctacagtt ttgacattga ttaagtttac agcagagacg ttacgagaaa cagagttctt
    44101 accataagaa ccgcatccca aagtcaatga cggaatcatt tcgttataga tatcaccgat
    44161 gccgccttct gcagatggtg tattcactaa aatacgacaa gctttcattc gaagaccgaa
    44221 tttgacatgc aactcttcgt tttctgaatg gataactgct gtatgtccta atcctccaag
    44281 attcaacata ccttcacaca aatcaaacgc atggtccgtg ttgttagctt tgatcatggc
    44341 aagaactgga gaaagttttt ctcttgatag cggataatct gggcctacgc cttccaattc
    44401 agcaatcagc attttcgttc cttttggtac actgattcct gccaattttg cgatttccat
    44461 cgcagaatgt ccaacgattg atggattgac cgcatatttt ccttcgttca tcactgcatc
    44521 ttctaatttt tgcaattcat ctggttttac gatataaact tggtgtgctt ggaattctgc
    44581 ttttactgct gcatagattt ctttatccac gatcacagct tgttcagaag cacaaatcat
    44641 tccattatca aatgttttcg aaacgatcaa atcgttcact gcacgtttaa tttttgctgt
    44701 tttttcaata taagctggta cgttacctgg acctacacct aaagctggtt ttcctgtaga
    44761 gtaagcagac ttgaccattc cagctccacc tgtcgctaag acgatcgcga tacctggatg
    44821 gttcattagc atagaagtcg cttcgatcga aggatgttcg atccattgga tacaattttc
    44881 aggagctccg gcagcgatag cagcatcacg taccactcgt gctgcttctg cagaagattt
    44941 ttgggcactt ggatggaaag caaaaacgat tggatttctt gttttcaacg cgatcattga
    45001 tttgaaaatc gttgtggaag tcggattcgt tgttggagtt actccgcaaa ccacaccgac
    45061 tggttcagca atttcaatca accctttttg gacatcttca ttgatcacac caactgtttt
    45121 atcatgtttg atattatgcc aaatatattc ggacgcatac atatttttga ttgctttatc
    45181 ttcgtaaaca ccgcggcctg tttcctctac agccatcttc gctaatggca tatgttgatc
    45241 caaagctgcc attgccattt catgcacgat atggtctact ttttcttgat caaagctttc
    45301 catttctttc aatgctgcat ttgctttttc tgccaaatca tcaatcattg cttgtacgtc
    45361 aattgtcttc gttttttctt tttctattac tttagccatc attatcctcc taatgggtca
    45421 tggttatttg ttaaataatt cacatgtata tcatacaata tttatttttc tatgtaaaca
    45481 cttttttgtg atttttttca cagttatttt taaatataaa attgctttat ttacaggtgt
    45541 ttgtatagaa aaatatataa agttatttat tattatttat atgacacacc cgattattca
    45601 atattgagca atatatccca tgctcttatc tctttctttt ttgaataaaa aatgaggtag
    45661 gacatctttc tgccctacct cgtctttaaa taagctttga tacttatttt tcttccttct
    45721 cttctgtctc ttccagcgtt tctgttgttt cagtttttac ttcaactgtc tcagctggtt
    45781 cttctgttgt ttcaacagta gtcgttgcat catttgttac gacagtccct ggtttgaccg
    45841 ttttgattgc tgcacgatcg tactcaagga agatcccttc gcagtctaaa acaactgtcc
    45901 gtttgtcatt gtcgatttct gaaacaactc catgtaatcc gccgatcgtt acgactgaat
    45961 cacctggttt catgctatct aacaagtttt gacgttcttg ctgttgtttc ttttgcgaac
    46021 gtgacataaa aaaccacatt gctaatagcg cgataaacat cacaagcatt ggtaatgttc
    46081 ccattttttt cacctcacta attctgtatc tacaaaaaac actttagcag aaaaatgctg
    46141 ataacactag ttttttactt aatttttaaa agattttcct ttagaagctt tttgcgtttt
    46201 ctttattgaa cccgtattct tcaaaaaagg cttctctaaa ttcaagcaaa ttatcatcca
    46261 tgattgcttg acgtacttgt ttcattagat tcaacaagaa gtataaattg tggtaagaag
    46321 tcaaacgaat cccaaatgtt tcatcacatt tgatcaaatg gcggatatag gcacgtgtat
    46381 agtttttaca tgtataacaa tcacatttct catcaattgg acggaaatca tgggcatatt
    46441 tcgcattttt cactactaga cggccttgag aagtcataca tgtgccattt cgagcgattc
    46501 gagtaggcaa gacacagtca aacatgtcta ctccacggat aacaccatcg atcaatgaat
    46561 cagcagcacc gacacccatc aagtaacgtg gtttgttttc ggggatcaac ggtgtagtga
    46621 attctaatac acgattcatt tctgatttag gttccccgac agataacccg ccgattgagt
    46681 aaccagggaa atccatcccg actagatctt tcgcgctttg acgacgaaga tcttcaaacc
    46741 ctgctccttg gatgattcca aataatcctt gacggtctgg attagcatga gctttcaatc
    46801 ctcgttctgc ccatcgagac gtacgttcta ctgatttttt cacgtagtcg taactttcat
    46861 cgaatggtgg acattcgtca aaactcatca tgatatcaga gcccaattta ttttggatgt
    46921 tgattgcttt ttctggtgat aaaaacatac gcgaaccgtt caagtgattt ttgaaatgca
    46981 cgccttcttc ttcgatattc cgcatatcac ttaatgaaaa aacttgaaag ccgcctgaat
    47041 ctgttaaaat cggttgatcc cagttcataa atttatgcag tccgccagct tcttctacta
    47101 agtcttcacc agggcgtagc cataaatgat atgtattact taaaataacg ccagcaccca
    47161 tttctttcaa ctcttctggg gacattgttt ttactgtagc taatgttcct actggcatga
    47221 acattggtgt ggggaaagtt ccgtgtggcg tgatcaattc ccctaaacgc gcgccagtat
    47281 gtttttcttt cttgattaaa cgatagcgaa tggcaggttg cgtcattcat ttccctactt
    47341 tctatataaa atatcttgac aactcccacc atcataatcg tttcaagtgc tttttgcaag
    47401 ttccctcggc ttccttctac tttatttaat attctttttt ttatcctttt tttatgaata
    47461 acaaaaaaaa gaaaaacatt atgacagaaa tattttttga tacatggtat attggtgtta
    47521 ttaaagaaaa ggagggaaaa atcatgcaat cttctgcaga attaaaacgc caagcaaaag
    47581 agagtctaaa aggacgttgg ggacaagctg ttttactaaa tctaatccct acattgattg
    47641 gtattgctac tattcttctt attatgattc ctattatctt gtttgccacc accatatatg
    47701 atggatcagc gagcgtctca gaagcgacaa cttcaggagg cggtagttca ggaggcggtg
    47761 gcggaattat ttccagcatc attagcgctt tgttcatgag cggtatttct tggacttatc
    47821 ttgatatttt acgtggacaa aaagatcaga tcgaaccatt caaagatgca tttcgtggat
    47881 tcaaaggttt gtttatcggc ggagtgatca gcttagctgt gctgatctcg atctttacaa
    47941 cattatgggg tttgctatta gttattcctg gaatcattaa aagctattct tattctcaaa
    48001 gctattttat ttactacgat atcgtccaag aaacaggaca aacacctaaa gtactggata
    48061 cgatcactgc aagtcgaaaa ttgatggatg gttataaagg acaacttttc tggttagatc
    48121 tttcatttat cggctggcat atcttagcat tagcaactgc tggtattggt tatctatggc
    48181 tcagcccata catttctgca acaaaagcag cattttatga acaattgcca aaagatattt
    48241 aaaagagagt gtgacttgtg accgaggggg tggcaggaga acaccgttta tcgagaggca
    48301 gtaaaagaaa cattcagccc attagcaaaa aggaggtgtg acaacattca tgtcacacct
    48361 cctttttgta tagttccagt aaaaagaaaa tcaacttaga aacagttaat cattcctctt
    48421 cttctgcttc cggtaatcga tggaacttga tcagttcatt caccgcgatt ggtacgatag
    48481 ataaaatccc taccaagaac cagtgattca aactgatgtg tactaggccg aatagttctt
    48541 gcgtaaatgg cagcaaagca acagccgttg taatagctaa tgccagtaac gccatttcta
    48601 ccaaagcttt attggtcgct aaattgactt tgaagatcga ttggctgctg cgtacattga
    48661 acacatgcag aatcgatgaa taagctaaga tcaagaatgc aacagtttga ccgacatgct
    48721 gacttgcgtc tacccatggg ctgatagtat cgacataact acctaaataa taaccaaaca
    48781 aggttacgat ggtgaagacc cctgcattta tggcaatttt ttgcaataaa cctcgagcaa
    48841 agatcccttc atttttcgga atgggtggct gatccatgat gccgtgttcc gctggctctc
    48901 ttcctaaagc aaatcctgga agtccatcag caactacatt gacaaacagt agttgcacag
    48961 ctgtaaatgg tgctccccat cctaacagca tcgcaatcaa aacaataaag atctccgaaa
    49021 tattacagct tagcaaaaag ttgatagctt tacgaatatt ctgataaacc gaacgtcctt
    49081 gactgacagc gtctacgatc gtcgcaaagt tgtcatccgt caaaatcata tctgcggcac
    49141 tttgcgccac atctgttcct gtgatcccca tggcacaccc aacgttactt gctttcaacg
    49201 ctggtgcatc attcacacca tccccagtca tcgctacgac tgcacccgta cgttgccaag
    49261 atttgacgat ccggatcttg tcttctggcg ttacccgagc atagacagag agagctttga
    49321 cacgcgcatc taattcttcg tctgataatt gatgcagttc tgatcctgaa agtgcttctg
    49381 acggatcatt caagatacct aattctttcg ctatggcact ggcagtcacc acatgatctc
    49441 cagtgatcat gactgttttg atgccagcct ttttcgctcg cttgattgct cctttacttt
    49501 ctggacgtgg tggatcgatc attccgatca gaccaatcaa acgtaagtct ttttccagtg
    49561 cttcagaaga aatatcttgc ggttcttcgt cataagtagc ataaccaaca gcaatcactc
    49621 tcagtgcccg tttaccaaag cgatcattaa cgatcgccgc ttgttctaca tcgcctgaac
    49681 taaagcgcgg agcaagaaca tcgaatgctc ctttggtgat tgagatgtat ttttcgccca
    49741 tttggtgaac tgttgtcatc atttttcgtt cagaatcaaa aggaagctcg tttactcgtg
    49801 gatatttttc ttctaattct gcctttgtat gataattctc ttcaacagcc cttacgatgg
    49861 ctacttctgt tggattacct ttgataacaa ggtcgtcatc ttcttgctcg accgtcacat
    49921 ctgtacatag tgcagccatt ttcaatattt ccatcgcgct gttcgtcatt gaatcttcga
    49981 tattcgttac ttcatcttct ttgctccata cccggcggac gcgcatttca ttttgtgtca
    50041 gcgttcctgt tttgtctgag cagataacat tagcggttcc tagcgtttca actgctggca
    50101 actgtcggat gatcgcatgt ttcctcgcca tcttctgcac accgtatgca agtgtcaacg
    50161 taacaataac agtcaaggtt tccggtacag ctgcaacagc caaggaaatc gaagtcatga
    50221 acatctcaag gagtggttct ccttgcagtt caccaatcac aaatactaaa gccgcagccg
    50281 ctaaagcgat catactgatt cgtttgccta gctgattcaa tcggacctgt aaaggtgttt
    50341 tttgcatagt attttcgttc aaaagatccg cgatcttacc catttctgta gccatgccaa
    50401 tggcagtgac gatcgctttc ccacgacctg cagcaaccgt acatccttta aataccatat
    50461 taagttggtc acctaatgac tcatcttctt cagcaataaa tgctgcatct ttttcaactg
    50521 cttcactttc tccagtcaac gccgattctt ctacacgtaa ttgtgatgct tcgatcaaac
    50581 gggcatcggc agaaatagca tcaccggact ctaaaacaag aatatcaccc actaccagtt
    50641 gctctgactc aacagtggtc actttgccgt ctcgtatgac agttgccgtt tgtttattca
    50701 tatcttgcaa ggattccagt gctttttctg cgtttccttc ttggacaatc gccaataccg
    50761 agttgatcac aacgatagcg atgatcagca gtccttcaaa taaatcccca tgttctgtag
    50821 caaatgcggt ataaaaggaa atcaccgctg ctacaagaag gatgatcgtt gtaaaatcgg
    50881 acaagcttcg aaagaatttt ttgatcatcg attctttcgg cgcctcatcg aatttattca
    50941 atccctgctt ttttcgccgt tcatccactt cttgtgaaga caacccagta tctggatctg
    51001 cttctgttac cttctttact tcttctattg tctgcttgta ttcttccatc ctattcctcc
    51061 tttaaaatct tcgtacaaaa aaaggtactt attttactat aacatccttt ttttatttac
    51121 ttcaaataaa gggcttatcg attatttgtt aagaaagcgt aaaatttaaa gtgcttatat
    51181 ttgcaaacgc taccaaagga tgctattata tagatgtaag gaaggaggat accatcaaat
    51241 agacagaaga atttctcgat agaacagtgt aagcaaacaa agttgttaga agtacaggtt
    51301 tcacccagac atgcgtgtag agtacaaacc tataaatagt gaatgcgtat ggatgtttgg
    51361 atcacgaagt atccgaaaca agaagtaatg cgatacgtaa caattgaata acgtaaacgt
    51421 ctgaaaattg aataggaaca agagatgttt caaatgttga agatgtaacg aaaacaaaat
    51481 ttttgtttaa catgaagaaa ttcaacaccg tgctttgcat gtatgatgga aagttacaat
    51541 catttctgtt tatttgaatc cttccgaggt acaagaaagc cgagcttatc gagagctcgg
    51601 ctttttcttt gtcataaaat ctttgtaaag cttttttgtt attcaaaact agcggctttt
    51661 cataacctta tttcacgaac atcgcatctc caaaactaaa gaaacgatag cgctcttcaa
    51721 tcgcatgctg gtaagcagat aaagtcaatt ctcttcctgc aaaggcacta actaacatga
    51781 ctaaagtcga ttttggcaaa tggaaattag ttgagaaagc ttctaccact ttgaattcat
    51841 agccaggcgt aatgaaaata tcagtccatc cgctgtctgc tttgatttct ccattaaatt
    51901 tcgttccaat cgtttctaat gttcgaattg aagttgttcc gacagccacg attttcccgc
    51961 catttttacg tacttggttc aatcgctcag ccgcttcttc cgtcaaacgg tagaattcac
    52021 tatgcatatg gtgttcttca attttatcta cgctgacagg tcggaatgta cctaacccta
    52081 catgtagtgt cagatagact aattcaacac cctttgcttc gatctcatca agtaattctt
    52141 tcgtaaaatg caatccagct gttggcgctg cagcagaacc attttctttc gcatagacag
    52201 tttgatagcg atctgggtct tccagacgtt ctttgatata tggaggcaat ggcatttctc
    52261 ccaatgattc aagaatctct agaaaaattc cttcatactc aaagtcaatg atccgtccgc
    52321 cgtgttccaa ttcttctttc actactgctt gcaatctgcc atcaccaaaa gagattcttg
    52381 tcccaacttt ggcacgtttc gcaggtttga tcaatgtctc ccacgtatct ccttgtgtat
    52441 tcgttagaag aaggacttct aaatgcgcac cagtatctgg tttttctcca tataaacgag
    52501 caggcagaac tcgtgtatta ttcataacta gcgcatcacc aggctgtaac tcttcaatga
    52561 tttcatggaa atgtttatct tccatctctc cagttttccg atccaaaaca agtaaacgag
    52621 aatgatcgcg gtcttttaat ggtgtttgtg cgattaattc ttccggcaag tcaaaatcaa
    52681 aatcttctgt tgttaacata tcgtcactca ctttctatca tgtgcttcat cattctatca
    52741 tgtttttcgt tctgttggca aaatcagcac tttttcactt ctattttttg ttttcctaaa
    52801 taaaaaaact accctatttg tattttttca ttgttttagg catactagta atagatagtt
    52861 cttcattgaa aatagaaaaa gaggtggcac catgattgaa tttcaaaatg tgtcaaaaat
    52921 ttataaaggt ggaaaagtcg ctgtagagga cgtcaatctt tcatttgaaa agggtgagtt
    52981 catttgtttt atcggtacga gcggaagcgg aaaaacgacg acgatgcgga tgatcaaccg
    53041 aatgactgat ccaacacaag ggaaaatttt gattgatgga aaatccatcc aagaaattga
    53101 tccagtggaa ttgcgacgtc agatcggcta tgttatccaa agtattggat tgatgcctca
    53161 catgacgatc cgtgaaaata tcactcttgt ccaaaaattg ttgaaagtca gtcaagaaga
    53221 acggaataaa acagctgaaa aaatgattga tcttgtggaa ttgccccgtg agatgttaga
    53281 tcgctaccca catgaattat ctggtggtca gcagcagcgt attggagtcg ttcgtgccct
    53341 tgcagcgaat caagatatca tcttgatgga cgagccattc ggtgcgcttg atccaatcac
    53401 tcgtgattcc ttgcaagacc ttgtcaaaga tttacaagag cgtttgggaa aaacgatcgt
    53461 atttgtaacc catgacatgg atgaagcgat taaactagca agccgtatcg ccatcatgag
    53521 tgaaggccgt gtgatccaat ttgatacacc agaaaatatt ttacgtcatc ctgcaaacga
    53581 tttcgtagaa gagttgattg gagaagatcg cctactacaa gccaagccaa atgcgacaag
    53641 agtcggcgaa gttatgctaa atacagcaat cacgattaca ccggaaaaat cattacaaga
    53701 agcaatcaaa ctgatgaggg aaaaacgtgt agatacgttg ttagttaccg ataattcgaa
    53761 tgtattaaaa ggatttatcg atgtagaaac gttgaataaa aaacgaggaa aagtatccag
    53821 tgtcggcgac attttgaata aacatgtttt ttacgtaaaa gaatccgcct atcttcgtga
    53881 taccttgcaa cgcattttaa aacgcgggct gaaatacgtg ccggtcgttg atgaacagaa
    53941 caaagtcgta ggtatcctga ctcgtgcatc attagtggat atcgtctacg atgtgatttg
    54001 gggagaagat cccgcaacta ctgatgttgc agagtcagct actcctgaag aatctaagga
    54061 ggtctgacct atgcagcagt tttttcatca gcacggttca gaaattctct caaaaggttt
    54121 tgaacatctt tatatttcag gacttgcttt gatcattggt atcatcattg ctgtaccgct
    54181 tggtgtctta ctgacacgtt ttccaaaagc tgccacgatt gtgattggct taaccagtgc
    54241 cttgcagaca atcccttctc ttgctttatt ggcattgatg atcccgctat ttggcgtagg
    54301 taaattacct gcgattatcg cactctttat ttattcatta ttgccgattt tacgtaatac
    54361 gtacattggg atgaaaaatg tcgattggaa ttatcgggat gtggcaaaag gcatggggat
    54421 gactgagttc caatccattt tttccgttga attgcccatt gctatgccaa cgatcatggc
    54481 tggtattcgt ttagctgccg tttacgtgat tgcatgggct acacttgcct cttatatcgg
    54541 cgctggtggt ttaggcgatt tgatttttag tggactgaat aattaccaac cagatctcat
    54601 tttggcaggt acgatccctg taacaatttt agcactattg gctgattggc ttctaggtct
    54661 cttggaacac cggctgacac cgatcgcact tagagaggag aatgaagaat gaaacgtata
    54721 ctaaaaatga ccatggttct tttctctctt cttatacttg cgagttgttc cttccctggt
    54781 cttgccagca atacagatga agacaccatt tcgatcacag gtggaatcac ttcagaagca
    54841 cagatcttag caagtctagt tgccggaatg gttgaacatt atacagataa aaataccgca
    54901 atcatcaaca atctggctac tacaactatc aaccatcaag cgatgatgaa cggagatgct
    54961 tcaatttcag cggctcgcta cacaggaaca gatttaacga ctacattgaa ccttcctcct
    55021 gaaaaagatc cgaaaaaagc gtttgctacc gtgaaagatg aatttgagaa aagatacggt
    55081 caaacgtggt tcccgtccta tagttttgaa aatacgtatg tctttcttgt tcgaaaagac
    55141 accgcacaaa aataccatct atctaaagtc agcgatctga aaaatgtagc ggatgaatta
    55201 gtagctggtg tagatacttc ttggatcaat cgtaaaggag acggttatga cggcttccaa
    55261 gaaacttatg gcttctcctt caattcgata ttacctatgc agattggact tgtttatgac
    55321 gcagtcgaag caggaaaaat ggatattgtt cttggctact ctacggatgg acggatcgcc
    55381 agttatgatc tagtcatgtt ggaagatgat cgtcaattct tcccaccata tgatgctgct
    55441 ccagttgtag acaacaagat attagctgat acgcctcatt taaaagaagc cttaaataag
    55501 ttaggtcata ccatcagtac ggaaaaaatg caggaattga actacgaagc agataataat
    55561 ctagtggaac catcagtagt agcacaacgt ttcttacaag aaaaccacta ttttgaaggg
    55621 aagtgaagca attggataaa atgaatgtct ttcaacaatt tttctattat ttccaggaaa
    55681 atggctccta tatctttgca caatttatcc gtcacttcct gatttctatc tatggtgtcc
    55741 tctttgcagc agttgtcggg attccggttg ggatcatgat ttctaggaga cgtaaattag
    55801 caaactgggt gattcgtttg gcgaatatca tccagacgat cccttctcta gccatgatct
    55861 ccattttaat cattggatta ggcctgggag tcaatgtcgt gattgttact gtatttttgt
    55921 attccctctt accgatcatc aagaatacgt ataccgggat gatccaagta gacaaaaaca
    55981 tccttgatgt cggcaaaggc atggggatga ctgctagaca acgactattc atggtagagt
    56041 taccactctc tgtttctgtt atcatggcag gcataagaaa cgcgttagtt gttgccatcg
    56101 ggataaccgc gatcggtgca ttcgtcggtg ctggtggtct tggagatatc attatccgag
    56161 gaaccaatgc aacagagggc acatcgatta ttttagcagg tgcattgcca actgcattaa
    56221 tggcgatcat cacggactgg cttttaggta ttttggaaag acggctagat ccagccagcc
    56281 gtacatcacg ctgatgttat tgtaaaaaac aaaagcttct gcgaccattt gttggtcgca
    56341 aaggcttttt tagttctgtc atttttaagg caataatcca ctctgattct tccctcctta
    56401 tgggcaaaga gttgcttttc ttagctattt atccattccg tatactccaa cttcatactg
    56461 ccaacgggtt catatctgca tccaccgact aagttttttt cttatccgct aaggcatttt
    56521 gccaatccat tttcccatca ctcgtcatgg aattcatacc acatgatctc taaatactcg
    56581 tctgcttgtt ctttgaattg ggcatcaatt cttacatcct ttggcgtggc tttcatttaa
    56641 gccttttcca tcagtcctcg attgttcgat gccttcagct gcatcatcaa aactggtgac
    56701 tgccgtatcg gtaacttcga tcatctttta tacaatcggg aacttgccat cctcatcctt
    56761 ggctaaaaac atatctagcc attccagctt ctcgccatgg gaggtttgcg gttcctaaaa
    56821 ccggtacacg attcttatgg actgcatccg tcgcaactag acttggcgat acgatgatcc
    56881 ttcaccagaa gagcaccccc gtaaaccaat tgatcgatat attgccaata agaaaagaca
    56941 ttggcgtaaa agatatcgat ccctcgtgat gcattgccgt tgatactgct attcatggcc
    57001 gaaagcgcca cgactttaac ttcttccgtt tgagtgacat tcatgttcgg caatgtcgct
    57061 ttggataccc gctctgctaa aggaacgaca ctggtattgt atttcgtatc tgtatctttt
    57121 ccaaaagacc atgccaacga atcctctggg aaccaataag acgactccgg ttgattgtcc
    57181 attgcttttt tcaacatact tttggctgtt tctcgataaa cgacatttcc aattgtcttc
    57241 gcctcacttt ggcgataatc gatggtcgtt gccactgcca acactaacaa cgatgctcca
    57301 attttactga ttttccttgt cacacttctt cctccttgtt ttacataaac ccgtcaacat
    57361 tccattccta aactcaaaca atgacccttc aaaggtggag atataggaac aaattaaaga
    57421 aatcatgcaa taaatccaag aaggttggtt ttagaacaaa aaaagagtct cctttttggg
    57481 gagactcttt gttaactatc taaaaaggtt ggctcttctc acttcactca taatgtgtcc
    57541 aggcagaata aatttctaca actttatttt cctcatcaac tttgtaaacc actcgatgct
    57601 gtctattcag cctgcgtgag tatctgcctt catgtgtagg tctcagcttt tcaaaagact
    57661 gcgtgggcat atatggatct tccttcaatg tctgaatcac ttcttcaaat tgtttcttta
    57721 aattcgtttg cttgattttt cttaaatcca ctttcgcaga gtttttgatt gcgactgtat
    57781 agttactcat caaagagctt cccaatcaat atcatcgata ttcgtaaagc tactgtcgtc
    57841 tttttcgcgg tctcgtactt tatctaaagt acctgtttgc tcaagaaaaa gggtttcttg
    57901 aatcgctctc cagtcttcca gcccaatcaa tacagcattg tttccactac gatcactaat
    57961 aatctcgatt tcagtatgat tttcatttac ctctttcaat aactgataaa aatttttacg
    58021 agcagtgcta ggattcatcg ttgtattagc cattgtctct cctccttttt ctgatataat
    58081 tatagcgtac ttgattaagt acgtcaaaaa aatacaataa agcacttaaa ttcagcaaac
    58141 ttttcctctt ttttacatag agaaaaagac ccctttttag ggaggatctt tgtccacgct
    58201 cacttcttac tcctttacga ctagcggtag ccaaacgtaa agtaattggt aacaacgtat
    58261 catctttagc aaaggtcgaa tccaaagcct gtgagtctat gcaacaacac caatacacga
    58321 aggttcctcg ttgcagtgtg acttgattga tatcttgaat aacctgagga tacgcacgaa
    58381 agatttgtaa cggttattca aaactgattt tggccgtcaa gtcttctact gcctcaaaaa
    58441 tgattgcctc tttcgtctcc tgtcattcat gttcactatc gatttgatac ttgcttagac
    58501 cgttgggttt gtgaatcacc aattaaaaat ggcactgagt tatggtaaca aaaaatggtc
    58561 acttgacgag gctgagattc ctacttatga agacacatgg cacttaagag tcgaggtaaa
    58621 ggaagaagct gaaaatatag gaggctgtac attatttggc aaaggattcg gaaattatga
    58681 tcaagacatc aaaatcaaaa tgttttacag ctaaatagga agaataataa catttcatac
    58741 gctgttccca tctttaatgg cttatagagg gcacctttag ctgagaataa gacaaaacag
    58801 accctctagc ttcaattaag agctagaggg tctgtttttg attttaaaac ttggtttatt
    58861 tcttcaaatg gtagctatag gtgctgacaa cgatattttc acgccaagac aatcgcaatc
    58921 ttaaccgcaa acttgtttgg ttatggagaa tattctgcca gcgtctgttt ggtacaaatt
    58981 gaggaatcaa cacagtagtt gtatagtttt gtttcgctgc atttttactt acgatatcta
    59041 cataacggat aattggattt tcaatcgagc gataagaaga gtggacgatt gaaaaacgga
    59101 catctgggaa atgcttttta aattctgctt cgatttcttt ttctttttcg acatcttcgt
    59161 ctagcgaaac atgcatcgca acgacataat caccgatcga acgtgcgtaa ttcaacgcac
    59221 cgatatttac ccgtgtcaca ttcccgacta atacaagaac ggtattcccg tcataatcat
    59281 gtagttttgc atcattttct aaacgaagct gttctgctac ttttttataa tgatcatgga
    59341 tcttataaaa aatgaacata acgattggca taatgatgaa gaaaggccaa atgtccccta
    59401 accgatagac aaacaaaatc gcaatgattg catatgagat gaacgcaccc gtaatattgg
    59461 caatcgattt gcttaaccat ctttttcctt cttttttcca tttgacgacc atccctgttt
    59521 gagataaagc aaatggaatg aacacgccga tagagtataa cggaatcaag cgttctgttg
    59581 agccatggaa aataaacagc aatacgatcg aacctagcgc tagtgtgata atcccattgg
    59641 aatagcctag tcgatcccca cgatcttgat acatgtgagg catgaattta tcttttgcca
    59701 gattgtatgc aagaactgga aaagcagaaa aaccggtgtt agcagcaact gctaaaatca
    59761 gcgctgtagc aaattgaagg acgtaataca aaataccatg tccaaagaca gctttaccaa
    59821 tttgagacaa aacagtgact tctttttcag gaacgatccc ataccaatag ttgataaatg
    59881 tgatccccac gaagaagaaa cctaagatca atgccatcat cgtcaatgta gcagcggcat
    59941 tttttgctct tggcttctta aagaatggta cagcattact aatcgcctcc accccagtta
    60001 aagaggaaga accagaagaa aatgctcgta aaatcaaagc gatagaaaca cccggcacag
    60061 ccgctcctgg aagtgcagta gcttgcaatg gcacagcacc tgtcacgata ttatataaac
    60121 caacaacgat cagtaacgag atcacaagga taaatgtgta caccggaaat aataggaacg
    60181 atgcagattc cctcagccca cgaagattca gcatcatcag tagcaaaacg attgtcacag
    60241 aaatagcgac ttgatgaccg tagagtgctg gcaccgctga tgtgatcgct tcagcacctg
    60301 ctgagacaga tactgctact gtcaacatgt agtcgatcaa taaagagcca ccggaaatca
    60361 agccagcatt ctttccaaga ttctcactgc tgacgacata tgctcccccg ccatgaggat
    60421 aagcatggat gatttgacga tatgatagcg ttaatgaaat caataaaata ataacaaaag
    60481 cggcaatggg tagcgaatac cagatggctg cagcagacaa agcgactaaa acgacaacga
    60541 tttgttccgt accatatgca atagatgata acgcatcaga cgacaataat gccaaagcag
    60601 caaatcgggt taatttgtgc tcatcatttt cagcagattt taaaggctta cctactaaca
    60661 acctttttaa gtaatccaat ttctaaactc ctttacacac aattttactt caagttttat
    60721 agtcgaaaat ttatagtaaa caagatgtta tagtacgctc actgacctta aaagtcaata
    60781 aactttaaga aaataattgg aaaaaaacag aaaaatatca agcgcttttt caaacgcttt
    60841 aatacagcaa aaatctaaca tttttttatg ggctttttct ttgaattcta taataaaagg
    60901 atagaacttg acttagaaaa tcaagttcta tcctttttga tatcttaact tttggaagag
    60961 agatgtaagg ctgctttcta cccatcattc ttactactcg aagcatagcg cagttgtcac
    61021 aacctcttga taaacggtgt ttaaaagctt gcatctgcgg taataagccc aaccaaatta
    61081 aaaacataag aagctgtttt tatttggtcg ttcttattac ttgatgcaga gcagcttttt
    61141 tacaacctct tggtacacgg tgttcaatca gctgaccctc ggtattagct caaaaaaacg
    61201 gcaaaatatg aggaactatt tttccatttt tttctctaat actcaggtca aaacactgat
    61261 ttcacaacct ctttttttaa tgaaaaatat ggctctcatg cgccgcttct ttgaatttcg
    61321 tcattttttc ttcgatgaac ggatagattg ccgttcctac gattccaaag acaacaaaca
    61381 aaccgatcat gatccagatt gctttcgtag catttggcca ataaattcct cctgcagatt
    61441 cccgtaacaa gtttaccgca tgagtaaatg gcaagaacgg attgatcatt tggaagaatt
    61501 tccctgagac ttggatcgga tagttcccgc ctccgccaga gatcgacagt actaagatga
    61561 taatagcgat ccctttaccg acattatcga ataatgcagc caagacatag acgatcatca
    61621 tgaacgctaa ggcgatcaag acagcaaatg acacgctgta gaccggattt tggacatcta
    61681 ctcctagtaa gaaaatattc cctaatgtaa cgatcaagct ttgcgcaatc gccattgtca
    61741 aaaatgtcag catacgagca acgaattgtt ctcgtttcgt aaaattgttt cggtctttct
    61801 ttcctaaata gtattctgtc gtagcaacac ttgaaagaag aacagcgccg acccacagac
    61861 atagtgcagt ataaaacggg gtgctagctg aaccgttatt tgcgattgga taaagcgcat
    61921 tggtttgtag ctcaacaggt tgtgtaaaga agtcactttc ttttgttgcg tctagtttca
    61981 ataatttgat gacttcgcct agatcgactt cttgttcgcc ttttcggatc gcgtctgctg
    62041 ctttttggat accagctttg atatttggcc agtcattgtt gatcaagtcc gcagcagcgt
    62101 tcacagctgt ttcgacttct ggcatttttt catttactgt tgtcaatgta ccggtgattt
    62161 cattttttag tgctggccaa tcattttgga taaaatcagc ggccaatcct aatttttgct
    62221 gaatgatcgg taattcattg ttgtataggt ctgccccttc attgatgcca ttgacgatgg
    62281 tatccatatt tccattcagc attgtattgg catcatggat ttcttgtcca attgcaggca
    62341 tttctttttg atatttttct aaaattgcca ctgcattcgt tacagttgct ttcgttgagc
    62401 tgagaagcga atcaaagtcg atctggtccg ctttgctcag tgcgccttgt gcagtcccaa
    62461 tcgtatcgat gacttggtct agtagagaag tgacagtgga actgatttga cctgtattga
    62521 taccagcaat gatgccattg atattattaa caacggcatc aatttgatct agcaattcat
    62581 caatagcctt cgtgtcttca ttttgaacag ctgtgttcaa agcagatagg cggttttgca
    62641 gattgcttag caagggtttt aattgattta gctgatcaat aattggctgt aatttcgtat
    62701 ttccagcact tgtttgcaat ttagtcagga actcgaccag tttatcgatt gcattttgtt
    62761 gttgagatat tccgtcaata aagccgttca atacattgct gatgtttttc ttttcatcat
    62821 cagtcagctt accatcttca atagctgttc ttacagtatc tattaacgaa cctgtcgttg
    62881 ttgccacttg tccaattgac ttcaatgtaa catctacact gtttgtgatg cttggtatcg
    62941 catctttcag ctgagaggca cctgattttg tttggtttgc tagatcactt gcctgatttt
    63001 ctaaattttt cacatctggc aagatatctt gtacttgttg gatgatcgtc aagccttgtt
    63061 ttgcttcatc gattccttgg ttcattgtct cttggatcga agcaaaatcg ccgtcgatct
    63121 ctgctagttg cttaccggca ttttggatct ctgggatttt ttcttgcaaa tcaaggatga
    63181 tttttgcttg atctttcaac tcaggcattt tgtcattcaa tgcaacgact ttttcaccca
    63241 tctcatctac tttagggatg taatccacga attcatttgc tttattcagt ttttccttga
    63301 tttcaggtag ttgactttgt aattcgagga cttgttttgt gtagccgtcg atcgtgtcca
    63361 aattttcatc tgttgataaa atcatatctt taactttatt gatacttact aggttcgtat
    63421 cgatgtcgta acctatctca ttgaatactt tcaataaagt cgaactggct gttttgataa
    63481 attcatttgt gatttgcgat tggatcgaac ttgctccttt atcggtgatt ttcggtgcaa
    63541 tcgcattgat tttttcattt accgtatatt cgatttttgg tttcttgata tcaccactag
    63601 taaaactcag cagatcttct gagaaatcct ttggcaagta aatacctgcg taatactttc
    63661 cggaacggac tccgtcttct aattgttctt ttgaatcaac gaattgccat cctaattgtt
    63721 tatttttatg aagcgattcg atgacttgct ccccaatggc cacttcttta ccttgaaact
    63781 ctgctggctt gtctgcactg taaacagcaa ttggcagctc tccagtattt ccatatggat
    63841 cccataatgc tttgatgtta aaccacgcat atagcgaagg gatgatcatg atcgcgatga
    63901 tcagaagtgt tgcaatcggg tttttgaaaa tccgtttcca gtcaagcaaa tataatcgaa
    63961 gcgtattttt gattgactgc atagttctcc cccttcttct tttttcagct gaattacttt
    64021 accatgtatt tcatactttt ttcaatcggc ttttttcaaa aaagtcgaat ttttggacat
    64081 atcacggcaa ttgtctcatt gtaatctctt acatattgag aaataattaa ggattacagc
    64141 ctttacttta tcatgaaata aaagggaaag ataattttat gccaaagttt ttatctatta
    64201 tacgtatacg caaaaaagct aaaacatttt ttgtctttgc ccctacaaaa atgtttcagc
    64261 ttttttcgtt ttttattcct gtatttctta tttttcgaat gacaggatga ttttcccagc
    64321 aggaggatgt ccttcaacta gctgatgtgc ttggatgaca tgcttaagtg aagcagacag
    64381 attcattgaa ataaaaacat gaaaggctcc tttttggtag gctttgatta tgccagcaaa
    64441 ggcttctgca tctagatatt cctttcttgg aacaaacgat tcataaaagc cttccttttt
    64501 ttgccgcaaa tctagatctg ggaggtcatt taatgcaaca tacctgccgc ctggtttcat
    64561 gatctggatg ccggtttctc ctttgatact tcctttcgtc gcatcgatta caaggtctgc
    64621 ctgatcagca aattgcagac ctggatttgt tttatcataa gcagcaaatg ctgaagctcc
    64681 taattttttt accttttcct catttttact ggatgcactg gttaagattc ggattccctt
    64741 ttcatggaga agctggatca gacttgaccc gaccgcacct gatgctccta gtatcattac
    64801 agtatctgtc ggctggattt ccgtcaaatg gttgattaga ttataagccg taattcctgg
    64861 cgtgaccatt ccggctgctt cttcccaact cattttatct ggaatttttg ctacttttgc
    64921 tgatggcaac acgacttctt ctccgtaagt cccgccgact gcatggacag ctactcgatc
    64981 acctacatga acagttgtga catctgaacc aatctctgtc acaataccag cgccatcatt
    65041 acctggtaca taagggaatt tcaatgttcg tatctctttc atttctccta aacgcaaggc
    65101 aacatcataa ggattcacac tgaatgcttt tatttctaca cgaacatgtc cagaaccgac
    65161 ttctctggga tgagcatcga tttcttcaaa aacatcttgt gcttctccgt aaccgttaat
    65221 tgcaaatctt cgcatggtca ccatctccct ttttctttaa gtttacgttt atgcctttat
    65281 tttgacaaaa aaaatgtctt ttcgttttgg cgcatgattc aaaacaaaat agttgtcttt
    65341 tttcgcgtaa cgtgttaaat tatttatcta aaagcgtaaa gattacgatt tacgctaata
    65401 aaaaataatt ggaggaattt gttgatggct aaaaaatcaa agattgccaa agcaaaaaaa
    65461 cagcaagaaa cgattgaacg ctatgctgct ttacgccagg aattaaaagc gcaaaaagat
    65521 tacgaaggct tgcgtaaact tcctttagat gctcgtccag aacgattgaa aaatcgtgat
    65581 ttaatcgatg gacgccctcg cggatacatg cgtaaattcg ggatgtcccg tataaaattc
    65641 cgtgaattag cacataaagg tttgattcca ggagtaaaaa aagccagctg gtaatccaag
    65701 tctggctgta atgtaaagga ggagggcgca tggaccactc cttggatcat caaaaaagat
    65761 acgttcgctt cttctagcag aaatgctggt actagaagca gacgtatctt tttttacgca
    65821 cagctggtcc ttttttatat gtaaaggctg catggttact tcgctatatt tatttagtaa
    65881 caggagtcag tgcttcgata cccacactaa ttttcaatgc tcggtcaact tctgccataa
    65941 tgggtcgatc caaatggcag accttttctt tcaatcttga tttatcgatc gttctgatct
    66001 gctccaacag gataacggag tctctttcta ttcctgttcc agtagctttg atcccaatgt
    66061 gagtcggaag cttaggttta gccatttttg ccgttatggc cgcaacaatg atcgtcgggc
    66121 taaaatggtt acctagatta ttttgaataa ccaaaactgg gcgtgttccg ccttgctccg
    66181 atcccacgac tggagaaaga tcagcaaaat aaatatctcc tctttttacc ataggatcct
    66241 ccttattctt gatattctct tggtatccgc tgtcctaatc cgcaagccac ttcatagtgg
    66301 atcgtaccta attgatctgc tatatcctgc atagtgattt ctttgtctgc atttttgccg
    66361 ataagcgtca cttttgttcc gacaggaaat tcttgaggca atcggatcat cagttgatcc
    66421 atacatacac gcccaatcgt ttcacagtag ttcccttcta ccaatagaga aaaaccctgc
    66481 atctttcgtg gccagccatc tgcataaccg atcggtatcg ttccgatcca ctctgcttca
    66541 ggagtgatat atgtttctcc atagccgatt ccttcacctg ctgggagttt tttgacttga
    66601 atcaattcag aaaccagctc aagtgctggc tgcaatggat aaacttccgg tagtgcgtgc
    66661 ccagagggat taagtccgta cattgctact ccataacgaa tcatattgcc gattgtttca
    66721 tcatgccata aagccgttgc actattgctg acatgtacat atcgaggaag ttcgggaagt
    66781 tttttcagca cttctataaa gcgttctttt tgcagattcc aatatgtatc atctgcctga
    66841 tctgctgtag aaaaatgggt aaataaacct tcccattcta atacacgact ttctttgatg
    66901 aatgcagctg cctcttttac ttcttcaggt gtacaaaatc cgatacgacc catcccagtg
    66961 tctgctttta gatgaatcga aagaggcgtc tctagcttac ttttctctaa aacagcagct
    67021 gctgcttgca accattcccg tgtacctgca gttactgata aatcatgagc aacagctaca
    67081 gtcagtgcgt cgtaaggaac catattcaag ataaggatgg gctgagtaaa tccagcttct
    67141 ctcaactcga ctccttcatc taaatttgaa acacaaaagc ccgaagctcc acctgcaact
    67201 gctgcctcag ctgtttcaat agctccatga ccgtatccgt tcgcttttac tactgcaaac
    67261 aattcttttc cttgcggaag tcttgcaact tcatttgcta cattttcagt tatagctttt
    67321 ttatgtatca ctgctttcgt tgggcggtgc caagcgacaa ccatcgtttt tccttctttc
    67381 tagtcttcca aaataatttg tgcaaaagct gtttcatttg tatgagtaat actgacccat
    67441 acattgcctt catgaggtga acgcgtcaca acaggctgac cattttcatt ttttaaaatc
    67501 tcgacatctt gaaaggtaac ttttccgatc ccagttcccc aagctttaga gaaagcctct
    67561 ttgcaagcgt aacgcccgcc taaaaattct acttggcgat gaaaaggcaa ggactggaat
    67621 agtttcattt catcagaggt caagattcgt gcaatgaatt ttggtttttc ttcgatcagc
    67681 cgagtgatcc taggaagttc gactgcatcg atcccaattc cttttatcat atgcttttct
    67741 cttttcaata aatttagaac actctcattc taccaaatta taaccatttt gccacaaata
    67801 agtccacaaa taacaaaaat gaaagtttct cttaaaaaag agaaactttc attttatgtt
    67861 taatcgttat ttgaacggat tacaaatccg cgttttttat cattgtgacg tttaccgcca
    67921 tctttttggc tgttattatt tttgctataa ccgccttttg atttgtttcc acgataatta
    67981 ccgccgtcac gacgattacg gttgtttccg ccaccacgtt tgccattttt attgtatcct
    68041 tttttctgca ttggcaatgg gcgttctggt gtgatcttca ctggcactgc atcagctgga
    68101 tcttttgctg tcgtttttag caaaagtgca actaaatctt gtgcagaata ttcttctaat
    68161 aatttatctg ctgtttgcag gtatttatct agaccatttt ctgcaagttt tgtttcgatt
    68221 tgttcaactg cagcacctaa ttgacctttg aatgcttctt tttcggttgg tggacgtaaa
    68281 gtcgtcatcc gttttttcgt caagttttca atcacatgca agtagtccat ttcatttggt
    68341 gtaacgaaag tcacagacat accgcctttt ccggcacggc ctgtacgtcc gatacggtga
    68401 acgtagcttt ctggatcttg agggatatca tagttgtaca catgagtgac acctgaaata
    68461 tctaatccac gtgcagcaac gtctgtcgct acaaggatat ctaaatgacc gctcttaaat
    68521 gaacgcaata cgctcattcg tttttgttga gacaaatcgc catggattcc ttctgcacgg
    68581 taaccgcgtg cttctaatcc gcgtgccaat tcgtctacac ggcgttttgt acgtccgaag
    68641 acgattgtta attcaggtgt ttgaacatca aacaagcgag tcatgatatc gaatttttcg
    68701 tattcttttg cgcggacata gtattgatcg atcaagtcag ctgtcatttc tttcgctttg
    68761 atcttcacat gatgtggatt tttcatgaat ttaacgccaa tattcttgat agctggcggc
    68821 atcgttgctg agaaaagtaa tgtttgtctt tgatcaggaa cttgtgaaat gattttttcg
    68881 atatcttcca agaagcccat attcaacatt tcatctgctt catccaaaac taatgtttga
    68941 acggttccaa gtttcaatgt gtggcggtta atgtggtcaa gcatacgtcc tggtgtaccc
    69001 acaacgatat gtggacgatc tttcaagcca cggatctgac ggccaatatc tgctccgccg
    69061 taaacggctt gtacacgtac ttttttgtcg cgccctaaac gatataattc ttcttgtgtt
    69121 tggatagcta attcacgtgt tggtgcgata actaaacctt gtaattcgtg acgatctgga
    69181 tcgatttttt ctaacattgg taatccaaat gcagctgttt tccctgtacc tgtctgtgct
    69241 tgtccaataa cgtcttttcc agctaatgct agtggaatcg tttctgcttg gataggcgtt
    69301 gcttcttcaa aaccagcgcg ttcgactgat ttcaacaatt ctggtgataa ttctagttct
    69361 ttaaatttca aatgaatcct cctatatggt tgttaactga ggatgtagct tttttgctac
    69421 cccgtcgatt tgttcggtca aagtgtattg tttctttttg acagtggcca cgcacgtttt
    69481 tatccattct tagcccctgt ggcaccaccg aaaaatcact ttgcgaagtt taggcattag
    69541 aaaagccaaa cgggtcgcgt tcagctttat cattattatg acatctggct tcaacaagtt
    69601 gtttctatgg caaaaccagt ccaatttctc ttcatctttc ggcaataggt tattctaaca
    69661 tagtttttcg ttttctgcaa gtttacagat ttttatttca tttgctgaag ttgttctacc
    69721 acttcaaata agcccatgct gttgctgcct tttagcataa tactatctgt tgcttcaaga
    69781 ttttgtttga tagcatcaat caatttattc ttttcttttt caaaatagaa cacaggtagt
    69841 tgggggtatt tttggttcaa ttcttctttt agtgcatgca tttgttcccc ataaaggaaa
    69901 atcatggcga atttctcagg atcgatatgt tcactcattt gcgcatgcat atttaaagac
    69961 tctttcccta attccagcat atctgctaac acagcgattc tgcgtccttt tgttggcaga
    70021 tttttaaaag tatctaatac cagtcccatg gctgttggat ttgcattgta gacatcgctc
    70081 aaaatagctg caccatttcc tgccgttagc cattcggttc tgttttgagt gatagaaaca
    70141 tgggcgagcc cttggcgtat ctcaggtatg gacagtccaa agaagcgccc gatcgtatac
    70201 gcaatcaaag cattcgttac attataactt ccaggcagcg ggatcgtaaa tgtttctcct
    70261 tctactacaa aatcggtttg tgcttttcct tttgctgtca cttccgcatg aacatcgcca
    70321 tttccaatac cgaatgttgt gactgtttgt actaatgttg ccgttaaagg tgtcagcaac
    70381 ggttcatctg cgggcacaac gagtaatccg tctgatacaa gtccgtcagt gatttccatt
    70441 ttggctttag cgattccttc tcgcgaccca agattttcta tgtgtgcttc accgatcatt
    70501 gtgattgctg cagcttttgg ttgagccata agtgaaagtt ccgtgatttc attggcgtga
    70561 tccatgccca tttccaaaac gatcttttct gtatcttggg gcatgtgcaa aatcgtgtaa
    70621 ggaagaccaa tattattgtt gtaatttcct tgcgtcttat atgttttgta tttttcagac
    70681 aagacagacg cggttagatc tttcgtggtg gttttaccat tgcttcctgt aattgcaacg
    70741 acttctgcgc ctactttttc caagtaatag gttgccaatt gctgcatggc tttcaaagga
    70801 tctgctacag gaataactgg aaaatttttt ggagcttgtt caacaggcaa gctccaaaat
    70861 gaagcagatg ctccgtttgt gatcgcttgc tggataaatt catgtccatc tcgcgtacca
    70921 gcaagaggaa cgaataaact tccttcggtt atcttccggc tgtcaaattc gacattggta
    70981 atctttgtca gtgcagagca ttcgctgccc acggcttgtg caatttcttg tattgttaga
    71041 ttcattgaga tctctcctaa aaaaggttgt gaaaaaagcg tttggcctaa acggcgggtt
    71101 cgcatgactc tcacttccaa gtaaatttct ctattcgtat ttagaagcta gaatgaacgc
    71161 ggttacgcaa tcactccagc ctcttcttta tttctcttta ttcatttttt tcaaaaaaag
    71221 attgacgctg atggtatcga ttcattccta actggatcag ttcttcaatc aaatcaccgt
    71281 atttcaagcc catattttcc cataagagtg ggtacatact gaactccgta aatcctggca
    71341 tagagtttaa ttcattcagg aataattcat ttttatttgt caaaaagaaa tcgcaccggc
    71401 tcaatccgct tccacctaac atcgtgtaag ctaacttcgc gtactcttgc gctttttgat
    71461 aaacttcttc tggcacttcg gctggaatct gcatttcgat tttattattg atatattttg
    71521 cttcataatc atagaatgct acgtctttta cgacttcacc aggcaaagtc gtccgaacgt
    71581 cttcatttcc taatacagca acttcgattt cgcgcgcttc aattccttgt tcaacgattg
    71641 ctcgagaatc atactgatag gctgttgcta aagcattttg cagctcttct cggttttctg
    71701 cttttgtaat gccgacacta gaacccatat tcgccggttt gacaaacatc ggataaagca
    71761 aagaaccttc acattgatca aatacttttt taggattttc tttccattga ttcttaagta
    71821 ctggtacata aggaacttgc ggcacaccag cagcttgtaa aatatacttg gtcatgattt
    71881 tatccatggc acatgcactg gtcaatacgc ctgcgccgac ataaggcata ttcaatgtct
    71941 ctaagaagcc ttggatcgtt ccatcttccc cgtttggccc atgtaaaact ggaaaaacga
    72001 tggctccttc ttctttgatt tcgcccggat tgatcacttt tcctgtaaag ccttcctctg
    72061 tctgtccact tgggtcccat gaaagatgca agacatcttt gctggcaggt ttttctgtta
    72121 gtaatggacc tttgacccat tgtccttctt ttgtaataaa tacgagttga acttggtaat
    72181 aattataata aatggcattt aaaactgaaa atgcggaaag aatggacact tcatgctctg
    72241 cgctgcgtcc gccatatagt aaagtaatct tcaaaagatt gtcctcctgt attctaaatc
    72301 gttcagtgat ttactctcat attttagcac aaaacaaaaa taaacgaata acttatttat
    72361 aaaaaaacga gccagcttct aaaagaacga gcgtcattta ttttttgtca gctagattat
    72421 ttgtcccgtt ttttataaaa agttatgata aagaaaagga gggatgatga tggcgcaaac
    72481 aaatccacgc agccgcttgg cagaaatcat tcgagtgttc atcaattaca atgtagtgcc
    72541 aaactttgta cagcaaaaaa atcccgaaca ggtaaaaaaa gcctttgaag aactaggccc
    72601 caccttcatc aagataggac agatgctttc tgttcgagaa gatttgcttt cttctgcctt
    72661 cactcaaaca ttcaaaacat tacaagatag tgtacctagc gacacatttt caacggtcaa
    72721 aaagacgatc gaaacagaac tttctctttc attatcagat atattcgatg atttttcaaa
    72781 atcgcctttt gcctctgctt ctatggggca ggctcatcgt gccaagctga agaacggtga
    72841 cgcggtagtc gttaagatcc aacaccctaa catcgccgaa gagatccgac ttgatcttca
    72901 actatttgaa cgagcgatcc ctttgatcaa atacattcct gaaactagcg tagttgatct
    72961 aaaaggggta ctccaagaag taaaacgttc cttgatcaat gaaatggact tcttaaaaga
    73021 aagtcaaaat ggcgaacaat tctatcaaaa gaacaatggc tggaaagaga tccgcagccc
    73081 caagatttat gacgcttttt gttcgaaaaa agtgatcgtg atggaagaaa tgtctggtaa
    73141 aaacttgaat catttaatga acgccgaaaa caaaactgaa acttttatca ctggaattca
    73201 aaacaagcag ctgaaacaag aagttgcaaa gcttttagtt gagaacttta tgaaacaggt
    73261 gtttgatgat ggttttttcc atgctgatcc tcatccaggg aatctgctat tccatgtact
    73321 aacaaaagaa gaacagacac aagctagccg aaaaactgaa acagtccatg aaaaagagtt
    73381 cggttccttt gcttttcgag cctccacttc tgcagaagac cctgttgcgc catataccat
    73441 caactacatc gattttggta tgatggggca tctttctgca ggacttaggc aaaaactcac
    73501 acaagccgtt ttagcgctgt atacgaaaga tgcttatcga atcgaaaaag cggtccttcg
    73561 actttgtcag caagaaggct cgtttgatga aagtcggttc caccaagaac tgacaagttt
    73621 tcttgaacag tattatgatt ctcctattga tgaaatcaac ttgcaagaag tattcacaca
    73681 tgtcgtgacg atttgtcatc aaaataatct gcagttcgat cgtgatatca cgcttttgct
    73741 gaaagcattt gggacattag aaggggtgat ccgcgtcctc gatcctgaag tttccctcat
    73801 ggaagtcgct tcgccttttg ctcaacatta ttttctcact catctggatg tagaagatac
    73861 attgaaacaa agcggattag acttattgga agggatgaag gctgcgccta agatccctca
    73921 acagctccac catctattag aaatgtggac ttcgggacaa ggaaaagtca atttggaatt
    73981 gaaaaagcaa gacaaattat tgagcaggat cgaaagtatg atcaatcggc ttgttttcgg
    74041 tatgatttta gctgcattga tcgtagggtc ctccctgctt gtccaagcag cacctgtaga
    74101 aaacgcagag gtcgtttcct tattagggat atttacgtat gctattgccg cattcgtcat
    74161 tatttttttg gcaatcgatg cattgatcca aatgtataag aagaggaaaa agtagaaaaa
    74221 ggttgtgaca gaaagaatca gcttcaagaa ataagaaggg gttttacata aattgtttct
    74281 caaatttttg tgaaaattcg gcttattttt cgaagaggct acttctgaaa caccgagaat
    74341 aaaaaatgtg aaaaagctgt tctgcaccca gtaataagaa caatcaaaaa gggaacatgg
    74401 aacacattta tcctgtttcc ctgttccctt tttgatgtat tcgagcataa ataaaatacc
    74461 ttcgttacct actatcttct gtacttggta aaccttagtc aattgccttt tttaacgctt
    74521 gacgaaaaga catatgatct ttctccgtaa agggttttgg accctttgtc cttatgccag
    74581 cttttcttaa ctttccacta tgataacgtt gttctagaag cgtgccgata ttcgcttcgt
    74641 caaattcttt tccagagtga tggaacactc gcacaccctt cggcaataca agtgaagcta
    74701 aaccataatc ttgcgtgatc aaaaagtcat tcttcttaac cataccgacg attttataat
    74761 ccgcactatc agctccgcgg tctacgtaga cgatttggac atgattagcg tattctttgg
    74821 tcgtataatg gtccacactg gtcacgataa ccacgtcaag accataggat tctcctaatt
    74881 ttatgacatc ttcttttact ggagaaccat ctccatcaat gaatagcctc attctttttc
    74941 gccttcttcc ataaatgata aacagttact aatccgctca gtaaaagacc aacattgatc
    75001 cattttgcca agataagcag ttgtacactt tctatcggca ctgattcatg gttcagcgtg
    75061 atcaataata gatggattgg ctctcccatt tcttttgcta aaacaaacaa aagcgtcatc
    75121 aataaaaact ggtggatcac actcccttta ttttgagtag tatacttgac aacgatccgg
    75181 cgatccattg gaatagctgt atcagtttga taatattcct tatttagcca gctgcctgtt
    75241 actacgtgcc agaaactaag cagaaagaca cctatcgcaa aaccatttgg aatcaagagg
    75301 accaataaag aagaactcag tccaagcaat tgcatagcca atggagacca tgttaaacgt
    75361 ttcaaaatcc atggtccgac tatttttgct gcaatcaagc ctgctgcata aggcaaatac
    75421 ataaaaatcg aaagtttttc taatccgtac agtatgccaa cataaaaact gctaaataaa
    75481 aaaaggaaat tccctagcat tccatttaga aaagtaaaca gatttagcca gcttggcaac
    75541 ttccattcct tcttctggtg tcctaaaaca aacacgaaca agatgaacag cagcaagaaa
    75601 ccataaatag caagatcaaa aagcctttca tcgaataaca atcgggcatt tctcaaaaga
    75661 aacaataagc caaagaatat caaaaataaa acaagctctc gcgtagctac cagatttctt
    75721 ttgatgtctt tgaaatccag ttcgtaacgc ggataatgac taaccgtatg gtaggccatg
    75781 acgtaaaaaa gtgtataaat agtaaagctt gctgcaatct gagtcggtgc aggcaactca
    75841 atcgcttgat acaggagaaa tagccagata gctgcaaata agtacttttt cccatccata
    75901 ttgataaaac cttgcgtctt ttcgtgaaaa ttgaccgtgg tattagcagg tacaagccat
    75961 gctgcactca gccctagcaa aacacttgaa aaataaaata aaggaaaata aaatacgcct
    76021 aatattccaa gcaatgaacc agcaccacca atcagcagag cgatcatcag caacgtgtaa
    76081 ctatctagac caaatcgtag actgttgact aaaaatagtc cagtcatccg aaaggcataa
    76141 aacagcgtaa atggcaaaat cgtcagccaa ttatgcgagt ctgttagtcc caaaaataaa
    76201 agataaggaa taaaaataac cgtgttactt aagataaagg gcgttgtttg tgtaaaatta
    76261 cgcccaaatc gtttgagttt ttcgaacatg acaatggctc cttaaacagt cttataacta
    76321 atctgctctt cgattttagc attaaagggg aaataaacca attttacaga atatattctt
    76381 gtaaaaaaaa atacagaaag aagcataagc ttctttctgc atttttacgg tacttgatta
    76441 ctcaagcaga caagcccttc tccacaaaag tcttgcccga cacccctgca tccggcaggt
    76501 gataaagata gaaatcaatt atcctgtgcc tccaaaatca attaggagct ctgtaaacca
    76561 gagtccttct cgacccgtcg cataaattta ctttaacaca gttcctatgt ttatgcgaga
    76621 gcttttttca ttttataatc gaccatttga aatccttgac cgatatctga aataagttct
    76681 tctgtaatct caaatccttc atgcttataa acctcgattg cttgatgatt cccctgattc
    76741 actcgcaaaa agatctctct ttcctttgtt tgcgcagcaa gttcttcata ccagcgaaaa
    76801 actgaagaag tcaatccttg accacgtact ttatttagca aatataattt acttaaataa
    76861 atttttccat ttatctcttc ataagcagtg taaccgacag tcttttcttc gctttttaat
    76921 aaaaagtagg acacaccttc tgtcagttct ttttgaatct gtttttttga ctgataagtt
    76981 ttcagcatgt aatccacttg tttttgacca atgatcggca caaaaacttc cggccatact
    77041 tcttgtatga ctgccatcag ctcatccagt tcattttctg ttacttttat tttttccata
    77101 cacccacgtc cttttttaca ttataaatga ccttgcgctt gatggaataa aaagagcatg
    77161 atcatgctat acacacccac cgaccacggt ttcaagaaaa tcacaatctg cataaattcc
    77221 ctaaaagata atttcgtcaa accagctact agacagatca agtcgtctgg cgcaaaggga
    77281 agcagcaagg taacaactag tactttttta atatctttcg tttttcttgt cagcaattca
    77341 tcaaatttct gatacttttt tggcgataaa ataagctgga caaaggctac gccatagtaa
    77401 cggacaagca aaaatccgat tgcttcccca atcactaggc caatacaact atataaaagc
    77461 ccaaatccat tgccaaacat cagcatgccc gctactgagg agatccctcc cggcaaaata
    77521 ggaatgatca cttggatcac ttgcaacaga acaaatatca tcactgcata cttgccaaat
    77581 tgctggataa acgcttgcaa agacgtgctc gatcgaaaaa tcccatgatg ataagcataa
    77641 agaatcaaca caaagaaaaa aaacagacca ataatgggca tgatctgaag acatttttgt
    77701 aaaactgatc cttttttaga catctatatt ccccacatct tttttcattt attaaaactg
    77761 cctcct
//
LOCUS       DAFLWC010000003        63635 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.003, whole genome shotgun sequence.
ACCESSION   DAFLWC010000003 DAFLWC010000000
VERSION     DAFLWC010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 63635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63635
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.003"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..616
                     /locus_tag="L1V17_000176"
     CDS             <1..616
                     /locus_tag="L1V17_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBN1234972.1"
                     /translation="FVFAPLEGEDLASFLVGAAIMMIGMTLFLFGADYSMMEVGDLVG
                     KYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQQVYDISDGEIGRVLLIGIVSVGT
                     GVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFTSSEFMPIAFDSGGVTTGPVTVPF
                     ILALAGGMTSMIKQKKNENDSFGMVGIASLGPILAVMILGVIFQ"
     gene            613..1386
                     /locus_tag="L1V17_000177"
     CDS             613..1386
                     /locus_tag="L1V17_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBN1234973.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            1383..1781
                     /locus_tag="L1V17_000178"
     CDS             1383..1781
                     /locus_tag="L1V17_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HBN1234974.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            1966..2637
                     /locus_tag="L1V17_000179"
     CDS             1966..2637
                     /locus_tag="L1V17_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1234975.1"
                     /translation="MNFLVVLKDTLIERFTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            2696..3136
                     /locus_tag="L1V17_000180"
     CDS             2696..3136
                     /locus_tag="L1V17_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1234976.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            3148..3816
                     /locus_tag="L1V17_000181"
     CDS             3148..3816
                     /locus_tag="L1V17_000181"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBN1234977.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            3880..4503
                     /locus_tag="L1V17_000182"
     CDS             3880..4503
                     /locus_tag="L1V17_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HBN1234978.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            4559..4945
                     /locus_tag="L1V17_000183"
     CDS             4559..4945
                     /locus_tag="L1V17_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HBN1234979.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            5158..6549
                     /locus_tag="L1V17_000184"
     CDS             5158..6549
                     /locus_tag="L1V17_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HBN1234980.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            7160..7528
                     /locus_tag="L1V17_000185"
     CDS             7160..7528
                     /locus_tag="L1V17_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HBN1234981.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            7708..8649
                     /locus_tag="L1V17_000186"
     CDS             7708..8649
                     /locus_tag="L1V17_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HBN1234982.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            8718..9449
                     /locus_tag="L1V17_000187"
     CDS             8718..9449
                     /locus_tag="L1V17_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HBN1234983.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            9593..11773
                     /locus_tag="L1V17_000188"
     CDS             9593..11773
                     /locus_tag="L1V17_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBN1234984.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            11793..12275
                     /locus_tag="L1V17_000189"
     CDS             11793..12275
                     /locus_tag="L1V17_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HBN1234985.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            12291..13052
                     /locus_tag="L1V17_000190"
     CDS             12291..13052
                     /locus_tag="L1V17_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBN1234986.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            13183..14517
                     /locus_tag="L1V17_000191"
     CDS             13183..14517
                     /locus_tag="L1V17_000191"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBN1234987.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            14824..15309
                     /locus_tag="L1V17_000192"
     CDS             14824..15309
                     /locus_tag="L1V17_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HBN1234988.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            15302..15985
                     /locus_tag="L1V17_000193"
     CDS             15302..15985
                     /locus_tag="L1V17_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HBN1234989.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            16111..18756
                     /gene="polA"
                     /locus_tag="L1V17_000194"
     CDS             16111..18756
                     /gene="polA"
                     /locus_tag="L1V17_000194"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBN1234990.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            18801..19637
                     /gene="mutM"
                     /locus_tag="L1V17_000195"
     CDS             18801..19637
                     /gene="mutM"
                     /locus_tag="L1V17_000195"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HBN1234991.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            19601..20230
                     /locus_tag="L1V17_000196"
     CDS             19601..20230
                     /locus_tag="L1V17_000196"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBN1234992.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEILVGQIENWLFANRFL"
     gene            20282..20614
                     /locus_tag="L1V17_000197"
     CDS             20282..20614
                     /locus_tag="L1V17_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBN1234993.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            20926..21417
                     /gene="nrdR"
                     /locus_tag="L1V17_000198"
     CDS             20926..21417
                     /gene="nrdR"
                     /locus_tag="L1V17_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBN1234994.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            21440..22813
                     /locus_tag="L1V17_000199"
     CDS             21440..22813
                     /locus_tag="L1V17_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBN1234995.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            22813..23739
                     /gene="dnaI"
                     /locus_tag="L1V17_000200"
     CDS             22813..23739
                     /gene="dnaI"
                     /locus_tag="L1V17_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HBN1234996.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            23868..24308
                     /locus_tag="L1V17_000201"
     CDS             23868..24308
                     /locus_tag="L1V17_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBN1234997.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            24452..25153
                     /locus_tag="L1V17_000202"
     CDS             24452..25153
                     /locus_tag="L1V17_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HBN1234998.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            25150..26271
                     /locus_tag="L1V17_000203"
     CDS             25150..26271
                     /locus_tag="L1V17_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBN1234999.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            26286..27518
                     /gene="pepT"
                     /locus_tag="L1V17_000204"
     CDS             26286..27518
                     /gene="pepT"
                     /locus_tag="L1V17_000204"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBN1235000.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            27650..28558
                     /locus_tag="L1V17_000205"
     CDS             27650..28558
                     /locus_tag="L1V17_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBN1235001.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            28593..28865
                     /locus_tag="L1V17_000206"
     CDS             28593..28865
                     /locus_tag="L1V17_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBN1235002.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            28876..29922
                     /locus_tag="L1V17_000207"
     CDS             28876..29922
                     /locus_tag="L1V17_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBN1235003.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            30173..32782
                     /gene="clpB"
                     /locus_tag="L1V17_000208"
     CDS             30173..32782
                     /gene="clpB"
                     /locus_tag="L1V17_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBN1235004.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(32933..33619)
                     /locus_tag="L1V17_000209"
     CDS             complement(32933..33619)
                     /locus_tag="L1V17_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235005.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(33597..34091)
                     /locus_tag="L1V17_000210"
     CDS             complement(33597..34091)
                     /locus_tag="L1V17_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBN1235006.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(34111..35331)
                     /locus_tag="L1V17_000211"
     CDS             complement(34111..35331)
                     /locus_tag="L1V17_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1235007.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            35478..37313
                     /gene="lepA"
                     /locus_tag="L1V17_000212"
     CDS             35478..37313
                     /gene="lepA"
                     /locus_tag="L1V17_000212"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBN1235008.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            37509..38420
                     /locus_tag="L1V17_000213"
     CDS             37509..38420
                     /locus_tag="L1V17_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1235009.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGKLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEILKEINRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFKKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
     gene            39416..39667
                     /locus_tag="L1V17_000214"
     CDS             39416..39667
                     /locus_tag="L1V17_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235010.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            39750..40022
                     /locus_tag="L1V17_000215"
     CDS             39750..40022
                     /locus_tag="L1V17_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235011.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            40112..40351
                     /locus_tag="L1V17_000216"
     CDS             40112..40351
                     /locus_tag="L1V17_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235012.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            40498..44781
                     /locus_tag="L1V17_000217"
     CDS             40498..44781
                     /locus_tag="L1V17_000217"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HBN1235013.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            44880..45245
                     /locus_tag="L1V17_000218"
     CDS             44880..45245
                     /locus_tag="L1V17_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235014.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            45247..45699
                     /locus_tag="L1V17_000219"
     CDS             45247..45699
                     /locus_tag="L1V17_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235015.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            46313..47623
                     /locus_tag="L1V17_000220"
     CDS             46313..47623
                     /locus_tag="L1V17_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HBN1235016.1"
                     /translation="MYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLV
                     RMLIDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGH
                     LLSEVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPN
                     MLIAGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEE
                     MIICLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDME
                     ARNRVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYL
                     MTFGEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYD
                     FTVKEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            47646..47957
                     /locus_tag="L1V17_000221"
     CDS             47646..47957
                     /locus_tag="L1V17_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235017.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            48317..49573
                     /locus_tag="L1V17_000222"
     CDS             48317..49573
                     /locus_tag="L1V17_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBN1235018.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            49570..50115
                     /locus_tag="L1V17_000223"
     CDS             49570..50115
                     /locus_tag="L1V17_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235019.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            50116..50616
                     /locus_tag="L1V17_000224"
     CDS             50116..50616
                     /locus_tag="L1V17_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235020.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            50697..51253
                     /locus_tag="L1V17_000225"
                     /pseudo
     CDS             50697..51253
                     /locus_tag="L1V17_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            51273..51617
                     /locus_tag="L1V17_000226"
     CDS             51273..51617
                     /locus_tag="L1V17_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235021.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            51636..52547
                     /locus_tag="L1V17_000227"
     CDS             51636..52547
                     /locus_tag="L1V17_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBN1235022.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            52626..53618
                     /locus_tag="L1V17_000228"
     CDS             52626..53618
                     /locus_tag="L1V17_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBN1235023.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            53615..53833
                     /locus_tag="L1V17_000229"
     CDS             53615..53833
                     /locus_tag="L1V17_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235024.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            53846..54256
                     /locus_tag="L1V17_000230"
     CDS             53846..54256
                     /locus_tag="L1V17_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235025.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            54308..56836
                     /locus_tag="L1V17_000231"
     CDS             54308..56836
                     /locus_tag="L1V17_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBN1235026.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            56852..59062
                     /locus_tag="L1V17_000232"
     CDS             56852..59062
                     /locus_tag="L1V17_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235027.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            59070..60161
                     /locus_tag="L1V17_000233"
     CDS             59070..60161
                     /locus_tag="L1V17_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBN1235028.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            60182..60724
                     /locus_tag="L1V17_000234"
     CDS             60182..60724
                     /locus_tag="L1V17_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235029.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VGQEAQKIDAIKIYYVRSAY"
     gene            60919..61176
                     /locus_tag="L1V17_000235"
     CDS             60919..61176
                     /locus_tag="L1V17_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235030.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KGYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            61190..61522
                     /locus_tag="L1V17_000236"
     CDS             61190..61522
                     /locus_tag="L1V17_000236"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235031.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            61567..62115
                     /locus_tag="L1V17_000237"
     CDS             61567..62115
                     /locus_tag="L1V17_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBN1235032.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            62122..62574
                     /locus_tag="L1V17_000238"
     CDS             62122..62574
                     /locus_tag="L1V17_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235033.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
     gene            62671..63006
                     /locus_tag="L1V17_000239"
                     /pseudo
     CDS             62671..63006
                     /locus_tag="L1V17_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313007.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT        21516 a        10288 c        13673 g        18158 t
ORIGIN      
        1 gtttgttttt gcaccgttag aaggagaaga cctcgcttca tttctggttg gtgcggcaat
       61 catgatgatc ggaatgacgc tctttttgtt tggagcagat tattctatga tggaagtcgg
      121 agatctagta gggaaatata tgatcaaaaa gaaaagtttg accgttttgg tcagtttggg
      181 atttgctatc gggatcgtga tcacgattgc tgaaccttcc gtgcaagttt tgggacaaca
      241 agtatatgat atatctgacg gagagattgg cagagtgttg ctgattggga tcgtcagcgt
      301 cggcactgga gtatttctag cctttgcgct gcttcgggtc gtattcaagc tatcctatta
      361 tcaattgatg gctataggct acataggcgt tttgatcgcc tcatttttca ccagttccga
      421 atttatgccg attgcttttg attcgggggg agtgactact ggtccagtaa ctgttccatt
      481 tatcttggcc cttgccggag ggatgactag tatgatcaaa caaaagaaaa atgaaaatga
      541 cagttttgga atggtcggta ttgcttcgtt agggccgatt cttgccgtga tgattttggg
      601 ggtgatcttc caatgagttt ctggcagcaa gtgatagatg gaatcgaaat cgttaccatg
      661 gaagtcattt tggcagtggc acctatcgta atcctatttg ttttaatgaa tatcattagt
      721 tttcgtatgc gcaaaaagcg tttctttgac attatgaaag gtttcttgat aacgactatt
      781 gggttgatcc ttttcctgca cggagtcaat atggcttatg taccggtagg acagcattta
      841 ggcagtgcta ttgcgggatt gccttacaat tatatactgg ttccccttgg ctttttaatg
      901 gggttcttag tagggtttgc tgagccggcg attcatgtaa tgatcaaaca ggttgaagaa
      961 ttgagcgagg ggagaatccg atcgaaaatc atgctgatgg taatttcaat tgggatcggc
     1021 gcagcagtag gattgtctat gtggcgtttg ctcgtcggat tctctcttta ttatttcttg
     1081 atcccaggat acgggctagc atttatttta ggacgaaaag tggacaagat ctttttagca
     1141 atggcttttg ataacggtgg agtagcaacg ggcccgatgt gttcgacatt tattttatca
     1201 atgagcgtgg caatcgctgc acaaattgaa ggaagagatc cgatcattga cgggtttggt
     1261 gtggttgcaa tgattgcatt gacaccaata ttatccactt tagtactagg atatatttat
     1321 aaacgaaaag atgaaaaaga cagaatcgaa aaagaaagat tgcaaaaatt gggggaaagc
     1381 aaatgaaaga tcttgtagca ttgaatcttc acatgattgt gacgatcgtt gacggaggaa
     1441 tgggcgaaga tgttatcgac ttttcaaaag aagcaggtgc agcaggcgga acgatcttac
     1501 atggaagagg ttctggtgta catgattcag ggaaattttt aggtttggac atttcgccag
     1561 aaaaagatat tgtgttgaca ttagtacccg atagtttgac gaataaagta atggatgcga
     1621 ttggtcaagg catcaacatc gatattccag gtaatggtat ttgttttagt attgatgtag
     1681 acaaagtcat tggtatcact aagattcatc aatatcgaga aattatcgga atgcaagaac
     1741 ttttagatga aaataacgat agagaaaagt ctgaatcata gacaagcgtt tgaagaggaa
     1801 ataaacacaa acaagaaggc ggatgagcgt tatttccgct tttttgtttg tatttttctc
     1861 gtgaatactt atgaaatagt aaatttttat gaaattctac tctaagcatc agactttctt
     1921 ttcaaaatat gctattttaa aaatgatgaa aaaaggggga gaaaaatgaa ttttttagtt
     1981 gttttaaaag atactctgat tgagcgattt acatttctat atgttcaatt gcaggaaaat
     2041 aaaacattgc tgcatttttc accagagttc catctagagg ggctaacatt aggagaaatc
     2101 tatcaagcag aagggctgtc ggctgttttg cactttttta aggtagaatt ggaattacca
     2161 gtaaaagatt atatcgagct ttctcttgaa tcttgggatc gagcagtggt tgaactgttt
     2221 ccagaaggtt taatgatcga tacaaacgat gggaagatcc atctgactgc agcagaactg
     2281 caaaaacaaa tgcgttatca aatagatgac gaaaattctt tttctatttt tagacgtcag
     2341 caaaagattc taaaaagctt tttaaaagtg atcagtaaaa aacggaatct gatcaaaacg
     2401 acacagctgt tgaaaaaata tccaggtctg cttcacacgt ctattcaatt tcctcaattg
     2461 attacgatga tccatcgttt tatacgtatg caacagctac catctaagaa gctgtttctt
     2521 ccattgacgg acacatttcg agtagtcaac agagaagata aaaagaaagt gattgtgatt
     2581 gactttacca gaaatcggaa tgtccttcac caagttgcaa tggaaaaggc caattaaggc
     2641 tttttctttt tggatttttt tgtcataata aatattagat gatggaggag ataatatgat
     2701 gcaaacatgg ttagaaaggc taatacgatt tcagcagaac tatcacaaac ttatgcaggg
     2761 aagatatgcg aaatttgatc agttgaatcg cggtctattg atcgctgcgc ttgtctttag
     2821 tttgctaagt cgttggttgc cctatagaat cggacaattg ttgttcatcg tctttttcgg
     2881 atggatgata tttcgtttcc tatcaaaaaa aatctacccc agactaaatg agaatcaacg
     2941 ttatttgaaa tatcttgata gagtcaaaga aaaatatcat cagataaaaa acaaaaagca
     3001 agtcaaaatg gatcgaaaaa gttatacttt ttttgagtgc ccgaattgtc atcaaaagca
     3061 gcgtgcacct aaaggaaaag gacgaatacg tgtgacatgc aaaacatgtg gtataaaatt
     3121 cgaaacgaat gtttaaggga gaaaagaatg aaattagtat tattacgtca tggcgaaagc
     3181 gaagcaaatt ttgaaaatta ctggacagga tggctagatg tcgccttaac agaaaaagga
     3241 aaagaacaag cagcagttgc cggtcaaaaa atgcttgaag ccggacttca attcgatgcc
     3301 gtttatacct ctgttttgaa acgtgcgatt cttaccggac aagtcgcact agaagaaatg
     3361 ggtcagttat ggcttcctat aataaaaaca tggcgtctaa atgaacggca ttatggggat
     3421 cttgtgggta aaaacaaaga taagatgaaa gaaatatacg gaaaagatca agtaaaaaca
     3481 tggcgcagag gatatacgga agttccgccg ttaaccgcag aaaatagatt tgaccgcaga
     3541 tatgatcact tggatccgca tttgatccca tacggagaaa gtctggaaat gacagtgaat
     3601 cggatcattc ccttatggca agatcatcta gcaccaaaac taaaagatcg gcaagattta
     3661 ctagttgtgg gtcatggtaa tagcatccga gcactgacaa aatatttaga agatgttcct
     3721 gaagatcaaa tggatacgat cgatatccca aatgcacaac caatccagta tacattagca
     3781 gatgatttga caattctgga caaaaaaata ctttaaagaa cacctttatc taaaagtgag
     3841 agatagaaaa aagaagcaaa ggaatggaac aaaaggaaca tgaaaaatta tatatgggac
     3901 tttgatggta cattgtttga tacgtatccc gcaatggtag atggtgcatg gcaagcacta
     3961 aaagattttg gtatcagtat ggacaaaaaa gaaatctact tcaaaatgaa aaagtattct
     4021 actagttatt tgatcaatga atcaaacttg aatgccagag agtttaatga attatttcac
     4081 cgatatgaaa aagaaagtac ggaagtttcc cgtccatttc cagaaacgaa acaagtactg
     4141 gaaatgctaa aagacaacgg cggtcgtcat ttcatcctga cccaccgttt gacagaatca
     4201 acatggggcc tgttaaaaga acatcgattg gcacatctga ttgaggaagt agtagggatc
     4261 gatcaggact ttcctcgtaa acctgatcca gcatctttaa attatttgat cgatactttt
     4321 catttagaaa gaacagacac gatgatgatc ggcgatcgtc gtttagatat cgaagcaggg
     4381 aaaaatgcag gagtcgctac ttgtctttac gacatcgatc attttctggg tgagatcccg
     4441 gcagattatg tggtaggaaa tctgaatgaa atccttacct tgcagagcat cattaaaaag
     4501 tagtatcccc tttcaaagga gatatgttat aattttcata aaggagtgat aaaattatat
     4561 ggaaatcaga agacaaaaag aagttgtaga agcatttcat tatgatatga gattgccgaa
     4621 ccaagaagta gaaacagatt tgaaagtagg cttctcgcct ttaaaagaaa cgatcgaaaa
     4681 ctatccgaaa gaacatagca tcgtaggagc acgcttagag ttccgtttag tgtttgatac
     4741 atatgtttta tctggaagtg tgagtcagat caatcatatc ctcaatcgga aaattgaagg
     4801 tcaaaatgat gtcacacaag aagaagtgga cgagctagta gcaccgttat tcgatatcgt
     4861 acgccgaatg tcttatgagg tgacagagat cgccttagat cagcctgggg taaaattgaa
     4921 ttttcaatca gaaaaacaag aatagacagt aaaaacatac ctgcgataga ttaaagctat
     4981 cacaggtatg tttttttatt actaattgta agcaaaaaga atgtcatttc gataaaaatc
     5041 gtctaaaata taaaagtcac tgaaaaaaat tttttcagga ggatggttga agaatcattc
     5101 tcgggaacct ttacttcctt cgatggactt gtcattaata atatgaggag gagaaaaatg
     5161 acaacactca tcacagtttt agtggttcta gtttttgcgg cattattata tgtgttctat
     5221 cgtatgcaaa agcgccatac aaaattttca acacgcgtct ttacagcatt aggagttggt
     5281 atcgtctttg gcggtctgct tcaattgatc tttggtgtag acgacaaagt cgttactcaa
     5341 tcaatggaat ggatcgggat tgtaggtcaa ggatatgtat cattcttgca aatgctagtt
     5401 atgcctttag tgtttatttc gatcattggt gcattcacaa aaatgaaagt ttctgaaaag
     5461 ctagggaaaa ttagtgcgac tgtattgact tctttacttg gaacaacagc tattgcagca
     5521 ttgatcggaa ttggttcaac aatgctgttc ggactccaag gagctaaatt cacacaagga
     5581 gctgcagaaa cagcacgaat ctctgaactg gcaacacgtc aggaaacagt tgaaaactta
     5641 tcgattccac agcagatttt atcctttatc cctaaaaacg tttttgctga tttagcaggt
     5701 agtcgtgcaa caagtacgat tggagtcgtt attttcgcgg catttgtcgg aatcgcttat
     5761 ctaggcgtga aaagaaaagc gccaaaagaa gcagcattct tttcagattt agtcgacagt
     5821 ctgtataaaa tcattatgcg gatcgtgacg cttgttttgc gtttgacacc ttatggagta
     5881 tttgctttga tgacaaacgt tttggcaaca agtgattttg cagctatcgt caatttaggt
     5941 aaatttgtcg ttgcttctta cgtagcattg cttgctgttt tgattgtcca ctcactgatt
     6001 ttgattggtg caaaagtcaa tccaatcaac tatttcaaaa aagcctttcc ggtattgagc
     6061 tttgcgttta cttcacgttc aagtgctgga gctttgccat tgaatatcga gactcagaca
     6121 aaagctttag gagtagatga tgcaacagct aatttctcag caagttttgg tttgtctatt
     6181 ggacaaaacg gctgtgctgg cgtttatcca gctatgttgg caacgatcgt cgcaccagca
     6241 gctggagtga atgtctttag tttggaattt attttgatgc ttgtggcaat tgtaacaatc
     6301 agttcttttg gtgtagctgg agtcggtggg ggcgcaacat ttgcttcact gatcgtttta
     6361 ggggcaatga acttgccagt agcaatcgtt gggttagtta tctctgttga accattaatc
     6421 gatatggcac gtacagcagt aaacgtcagc ggtagcatgg tagctggtat cgtgacaagt
     6481 gcacgcatca aagatttaga tcgcgatgtc atcaatgatg attctaaagt gatcgatgtg
     6541 aatgcatagt caaaaagagg ttgtgataga agtggtcagc tttaagaaat aagaagaagt
     6601 ttcctaaaaa tagtttctca aatttttgtg aaatttcggc ttatttccga gaagctactt
     6661 ctgaaacacc gtgaataaga ggttgtgaaa aagctgccct gcatcaagta ataagaacag
     6721 ccaaacaaaa atagttcctc atattttacg tttggttgag cttattaccg cagatgcaag
     6781 cttttgaaca ccgtttaaga aagaggtcgt gagcctgccg tttcactctg agtcacaaag
     6841 agcaatttca aaaaatagct tctcatgttt gttgaatatt gtgtcttgtg accgaggagt
     6901 tgtcaggaga acaccgttta ccagaggttg tgacttgttt ttagtcacga cctctttttt
     6961 tatttattcc atataaatac acattattta ttccgaaaag tgaaagcgca aataacaaaa
     7021 acaaccaact tatttattat taaagaaaag cgtatttaag taggacgatt ctgttgagag
     7081 ctttcgtaga ttttcccatt ttcctatggt aaactgacaa agttgagaat gttagaacag
     7141 atcgtttagg aggaaacaga tgtttacgaa tgaaataaaa atcatgcttt atgtggacga
     7201 tgtagaaaaa aatgcaacgt tttggagagc agttggcttt gcggaaaaag atcgtcaaga
     7261 aatggatggg acgcttataa ttgaagtagg agttgaggac agtcaaacct catttctgtt
     7321 atatgatcga gcatttgttg agtcccattc acctggcaca gctactagtg ccccatcttt
     7381 gatgttttac agtaaagata tctttggact atataaaaaa atgcagacgc aatcagtcac
     7441 attaggtgat atggtacagc ttggagaaga atatgtcttt aactttgctg atcccgatgg
     7501 caactacttt gcggttacag gtaaataata gaaataaaga ctttgttttt ctgtgcgaaa
     7561 caggaaagcg aagtcttttt aattcaaata ataatattat gtaaacaaaa aactttccat
     7621 gcgtaattat acacaagcaa ataaatcgtc aaatgcgaac gccttcttta tactgtttag
     7681 gaacgaaaag aaggaaggaa gaaatacatg gattatcaag tactgcttta ttacaattat
     7741 acaaaaatcg aagaaccaga ggaatttgcc aaaaatcatt tagccttttg caaatctttg
     7801 gatcttaaag gtcgtattct agtagctgaa gaaggaataa atggtactgt gtctggaacc
     7861 gttgaaaaca cgactgccta tatgaaagca atgaaagctg atcctcgatt tgctgatacg
     7921 atgttcaaga tcgatccaag cgaaggacat gcctttaaga agatgtttgt aagataccgt
     7981 ccagagcttg taagtttaaa gctagaagag gacattgatc caaaccaagt gacaggtgcc
     8041 tatctttcac cgcaagaatt taaagaagct attttagatg aacagacagt ggtgattgat
     8101 gcacggaatg attatgaata tgacttggga cattttcgag gggctgtacg cccagatata
     8161 cgcagttttc gagagcttcc agactggatc cgcgagcaca aagaagaatt tatggaaaaa
     8221 cgggtagtga cctactgtac tggtggcatt cgttgcgaga agttttctgg ttggcttgtc
     8281 cgtgaaggat tcaaagatgt cggacagctg catggcggta ttgctactta tggtaaggat
     8341 cctgaagtcc aaggagaatt atgggacggc aagatgtatg tgtttgatga acggatcgct
     8401 gtcgatatca accaagtaga taaacaaatc gtcggtcgcg actggtttga cggaacacca
     8461 tgtgaacgat atatcaattg tagcaatcct gagtgcaatc gtcagattct tgcttccatt
     8521 gaaaatgaag aaaaacattt aggagcatgt agcatagagt gtgcgaaaca tccgcgcaat
     8581 cgctatgttc aagaccatgg aatctctcca gaagaagcag aactgcggtt tacagcttta
     8641 attaaataga aaacaatagt tttgattgtc gaccatttcc aatatgcgct atactagcgt
     8701 tgaggatggt gatccacatg aaatcattga tttatgctat tggggatgtc catggcaaac
     8761 atgagctttt tgaaaaactt attcactatt atgatccaaa gatccatcag cttgttttat
     8821 taggggatct caatgatcga ggtcctcgta caaaagaatg ttttttatta ggaaagcaat
     8881 tagtcgaaga aacaggagcc atttacctcc ggggaaacca tgaagaatat tttttgcaat
     8941 ttctgcaatc accggaggac tggtatgcgc cttatatgag aaatggtgga aaagaaacgt
     9001 ttgaaagcct gattcaccca ggggcatcgg aggaatactc cccaactgaa atctcgatga
     9061 tgatccaatc gagatattca gaactgatta aatttttagt ccagcgcccc ttgtattatg
     9121 aatgggaaaa ttatcttttt gtccatgccg gtgtggattt gacaaagaaa gactggcgta
     9181 agacaagtct aagagacttt atttggataa gggaaccatt tcatgaaggg aaaaacaata
     9241 caggtaagac aattgtattt ggacatacga ttacaccaat gctccatgga gatatgcaga
     9301 caacagacct ctggattcag gatcataaaa tcggaatgga cggtggggct gtattcggag
     9361 ggtcattgca tggggttgtt tttgacaagg aaggtattct tcaagatatt gaatatcaga
     9421 acaacgaagg accttggcat ggaatctgac taatggaaag aatgaaggag ctgtgacttt
     9481 gttgcggctc tttttatttt tatagagaat attgtttctt tcagtagttt aacccaggat
     9541 aaaaagtatg atagaataaa gaagcaattt ttagcagaaa agaggcattt taatgacgga
     9601 aaatttgaac cagacgatca ttcagcttgt acaaaaagaa ctttcagact atcgtcctaa
     9661 gcagttgact actgtactta atttgttaaa tgaaggaaac actgttcctt ttatcgcgcg
     9721 ttaccgaaaa gaaatgactg gaagtcttga tgaagtccag attcgtgaaa tcgaagagcg
     9781 gtatgcctat cttgaaaact tagaaaaacg taaaactgaa gtgattcggc taatcgatga
     9841 acaagggaaa ctgactcccg agttagaagc agaaatcacc caagccgtga aaatgcaaca
     9901 agtggaagat ttgtatcgtc catacaaaca aaaacgacgg acaaaagcaa cgattgctaa
     9961 agaaaaagga cttgaaccac tcgcgaagtg gctgatgcag cttacagatg gagaggtgca
    10021 atctgaagca gaaaaatata ttgacaaaga aaaagaagtc tcttctgccg aagaagcgtt
    10081 gcacggtgct catgagatta ttgctgaaca agtcagcgat aatgcaaaat ttcggacttg
    10141 gattcggtct tatacgtata acaaaggtat gtatgtcagc aatgtcaagg atgagcaagc
    10201 agatgaaaaa ggcgtatatg aaatgtatta tgactttgca gaacccgtcc ataaaatggt
    10261 ttctcatcga atattagcta ctaatcgtgg agaaaaagaa gatattctga aagtattctt
    10321 tcaagtagat gaagcagcaa ttttagctta cttggatcgc caaatagtca aaaatcctgc
    10381 ctctccttct tcttcattcg tcagagaagc ctatcaggat agttataaac gctttattca
    10441 gccagcaatc gagcgagaac tgcgcaatga attgactgaa aaggcagatg agcaagcaat
    10501 cgctattttc ggcgaaaacc tccgtaatct tttgttgcaa ccgccactaa aaggtaaagt
    10561 tgtcctggga tttgatccgg cttatcgtac tggatgtaaa ctagcagtcg tagatgcgac
    10621 agggaaagtt ttagcaatcg aagttattta tcctcataaa cctgcagcgc aagcaaaaag
    10681 agaagctgct ggaccagctt ttatccaatt aattaataaa tatcaagtag atatggtagc
    10741 tatcggaaat ggtacagcca gtcgggaatc tgaacttttt gtggctgagc agttgaaatc
    10801 cgccgaccat aaaacctatt acgctatcgt caacgaagca ggcgcttctg tttactccgc
    10861 tagcgaaatt gcacgaaaag aatttccgca tctacaagtt gaagaaagaa gtgctgtttc
    10921 tattgcccgt cgcctgcaag atcctttagc tgaattagtc aaaatcgatc ctaaagctgt
    10981 cggagtaggc cagtaccaac atgacgtttc tcaaaaacgt ttggctgaac aattggattt
    11041 tgttgtggaa acagcggtta accaagtagg tgtggatgtg aatacagcaa gcccgcagct
    11101 cttgcagcat atatcaggat tgaataaaac aactgcccaa aacattgtca tttatcgtga
    11161 agaaaacgga gaattcaccg cacgaactca attgaaaaaa gtgccacgct taggaccaaa
    11221 agcatatgaa caagcaatcg gattcttgcg agtccctggt gggaaaaaca ttttggacaa
    11281 cacaggtatc catcccgaaa gttattctat tgcaaaagaa atattaactt cagtccaact
    11341 ttcagaaaaa gagcttggta cagaagaagc agtagaaaaa ttgacacgat tatccgtaga
    11401 gaaactggct gaaagcctat cagtcggaga agaaacgtta gccgatattt tagctgggct
    11461 gacacaacct ggacgagata tgcgtgatga gatgccagcg cccttattac gtacagatgt
    11521 attgagtatg gaagacttga aaccagggat ggaattgact ggaacggtcc gtaatgtcat
    11581 tgacttcggc gcatttgttg atatcggtgt gaagcaagac ggacttgtcc atatatcgaa
    11641 actcagcaaa aaattcgtca agcatcctac agatgtcgtg tcagtaggag atatcgtaac
    11701 agtttggata gaacaagtcg atacgaaaaa aggcagaatc agtttgacga tgctttcccc
    11761 ttatgaagag taacaatgag gagtaacaaa aattgacaca agaagaactg cagcagttag
    11821 tagaagagat atcattaaaa agcttccagc ttcctttcaa gcaccaagca atgttcaatc
    11881 cacgcttacg tacaactggc gggcgctatc atttaaacga tcatcattta gattttaatg
    11941 cgaagctatt tgaagagtca gacgaagaga cgattgcagg aatcatcaaa catgaacttt
    12001 gccattatca tcttcatcta gctggaagag ggtatcagca taaagatatg gatttcaagt
    12061 atcttttgaa aaaaacagga gggttgcgct atgcaccagc cttgacgaag aaacagataa
    12121 agatggagta ttatcgatgc caagattgtt ctgccacgat ctgccgcaag agaagaatcg
    12181 atgtacgcaa atatcgttgt ggaagatgtc atggagaaat caaatggatt gagacaaaaa
    12241 gagaagactt taatgaagca caaaaaatca gatgaaagga tagaaggcct ttggaaaaaa
    12301 gtgagcagag gaatctaaaa gactggaatc agctattaaa ttttttagcc gcacctgaag
    12361 agggaaattt tgaggaactg acggcaccta cacttatttt agctggaaac tgtcttccta
    12421 tcttagctga taaagcagca caaatgtatt taaatggcca agtagatcaa ttgtttttgg
    12481 tcggaggggt ggggcatgcg actagaatcc tttatgagaa ttttgaaaag caaggatttc
    12541 attttgaaga tggcatgagt gaaagtgaaa tctgtcgtca gtatctaaaa gaagtctatg
    12601 atttgcccga taaggctttt ctgatagaat cgaagtctac aaattctgga gagaacgcca
    12661 ctttttcact ggagattctt cattccttag gagctgtacc agaaaaaatc ttattgatga
    12721 atgatccgac actgcaacgc aggactcgag caacttttga gaaagtatgg caaaatgaac
    12781 aaactatttt cgcgaatgct gtgccatttg tgccggaaat ccttcacttt tctgaagaga
    12841 tcatctttac agcaaaagaa ctgaatcatc aatggcctaa ggaatatttc catgcgctag
    12901 tattaggaga aatggaacgt ctccatgacg atgagaacgg ctatggtccg aaaggaaaag
    12961 attttattcc tcacattgat atatcagagg aagtttggtc ttcttacacc agaattaaag
    13021 agtcaataaa aacggatttt tctcgtactt gaccatttta gcaagcgaat cctcctttcc
    13081 aaataaattt ggttgaaatt ttcaatcgtt tataagataa tgaggagcgt gttgaatgta
    13141 atagctaaaa gaatggacgc tagataagag aagaggattc aaatggaaaa tcaaaataaa
    13201 ttgtatcatt ttgttggtat caaaggttca ggaatgagct ccttggctct tgttttacat
    13261 gaacaaggtc taaatgtcca aggatcagac attgaaaaat atttctttac acaaagagat
    13321 ttagaaaaag caaatatcac gattctgcca tttaacgcag ataatgtaaa accagggatg
    13381 acgatcattg caggaaatgc atttcctgat tcacatgaag aaatccagcg agcaaaagaa
    13441 ttaggtttgg aagtgattcg ctatcacgac tttattggtc attttatcca aaattatacg
    13501 agtatcgctg taacaggctc tcacggaaaa acaagtacga ctggactgct ctctcatgta
    13561 ttgagtggtg tccgtccaac aagttatcta attggagatg gaacaggaca tggtgatccg
    13621 caagcggaat tcttttcatt tgaggcctgt gaatatcgcc gtcatttcct tgcctattca
    13681 ccagactatg caatcatgac caatatcgat tttgatcatc cggattatta tacaagtatc
    13741 gacgatgtat ttacagcttt ccaaacaatg gctggacaag tgaaaaaagc tatttttgcg
    13801 tatggtgacg atgcttattt acgcaaatta aaagcaaatg tgccgattta ttattatggt
    13861 gtcacagaaa acgatgatat ccaagcacga aacatcgaac gcacaacttc tggttctgct
    13921 tttgatgtct atcatgggga tgaatttgtt gggcacttca ctgtaccagc attcggtaaa
    13981 cacaatatct taaatgcttt aggtgttatt gcagtagctt atttcgaaaa actggatctg
    14041 aaagaagttg cagaagaaat gctgactttc ccaggagtaa aacgtcgatt cagtgaaaag
    14101 atcgtagcag acatgaccgt agtcgatgat tatgcgcatc accctgcaga gatcaaagca
    14161 acgattgatg gcgcacgcca aaaatatcca gataaagaaa taattgcagt tttccaaccc
    14221 catacgttta cgcgtacgat tgcattgatg gatgaatttg cagaagcact tgatttagct
    14281 gataaagttt acttatgcga tatttttggt tcggctcggg aagaacaagg aaacgttaag
    14341 attgaagacc ttggagcgaa aatcaaaaaa ggtggagaag tcatcaaaga aaataatgta
    14401 tctccattgt tagattatca tgatgcagta gtaatcttca tgggtgctgg agatgttcaa
    14461 aaatttgaac aagcgtatga aaaactttta agcagcacga cgaaaaatgt actgtaatac
    14521 aattactgca gtgtccttat aaaaatagaa agagggggag tggcaaaaat cttgccaagc
    14581 cccctttttt gcaacttatg ataaacggtg ttcaaaagct tgcatctgcg gtaataagcc
    14641 caatcaaatc aaaaacatga gaagctgttt tttcttggct gttcttatta tttgatgcag
    14701 gacagctttt tcacgacctc tgtaaactat aggaatctgt taaatcaagg gagcagaact
    14761 tgccttttac gctacttttg gtacaataat gtatgattaa aaataaactg gagggtttct
    14821 atcttgaaca taggtaagcc gagaaaacta ggaaaaacaa taaatgaaat cgaggaaggc
    14881 gactcgttat ccttaacaga atctattgaa gataaccagc ttttgctgta tttgggattg
    14941 acgaatgatg caaatccttt gtatatccaa catgactttg cacaaaaaac agaatatcaa
    15001 cagccaatcg ttccatcagt gatgctgatg gggatcatca caagtgcaat ttcaaagcat
    15061 cttcctggac caggatcaca tgttgtcaat ttttctgtca attttattga accggttttc
    15121 cattatgaaa cactgacttt tcagtttgag gtcataaaag tagataagat gaaggatgtg
    15181 gtgacgattt ctgtagaagc ggagaatacg aacgaagatc gtgtgttgga tgctgtcgtt
    15241 atggtccaac cgccacaagt tcctgaattg gaaatagcaa tcgaaagtga aggtgaattg
    15301 aatgaataat ccaagtacat caatgtcagg tatcaatcgt ttttatgcaa aagtttatgg
    15361 atttttaggt atgggacttg cccttagtgc agtcacttct tacttggctc tttgggtatt
    15421 tcctttgcaa ttagcaactt ttatcaataa ttttccacta ggctttgtgg gtctgtggat
    15481 cgttgaactg attttagtaa tggttctagg cgtaaaagca caaaagaatc cgagcttagc
    15541 aatcggtgga tttattgcct actctctttt gaatggcata acattagcgg ttactcttgc
    15601 atactacgat attggaacag taacgcaagc tttcttgaca gctactttga tgttcatggg
    15661 gatgtctgtt gtcggagtaa caacaaaaag agatcttagc ggggttggaa gagcaggaca
    15721 ggcagcttta atcggagtga tcattgcact agtcttgaac atcttcattt tgagaagtag
    15781 cgtagttgag ctgttcatct ccctactgtt agtcgtcatc tttgcaggga ttacagctta
    15841 tgataaccaa agcatccgta atatctatgt ccagacaaac ggaacagcac atagtggaat
    15901 tgctgtattc atggcattga agctgtattt ggactttatc aacttgttct tggcgtttct
    15961 gagaatcttt ggacggaaca actaaaaaag aaaaaaattc atcagttggg gctataccga
    16021 attatttggt atggtcccgc tttttctttt cgcattccgc aggattcttt gttagaatga
    16081 ataagaactt tacagtaagg agttaagaag atgacaaaaa ataaattatt actcgttgat
    16141 gggaacagtg tggcttttcg cgcattcttt gcgcttcaca attctcttga acgtttcaaa
    16201 aatagaaacg gtcttcatac aaatgcaatc tatgcattca atacgatgtt tgaaaatgtt
    16261 atgcaaaaag agcaaccgac tcatgttctg gttgcgttcg atgcaggaaa aacgactttt
    16321 cggacagaaa tgtatgcgga gtacaaaggt ggaagatcca aaacacctgg cgaattcaaa
    16381 gaacaaatgc catatatacg tgatttgttg acaggactag gggtacagta ttacgaattg
    16441 cccaattatg aagcagatga tattatcggt actttggcag aaaaagtaga caaagatcaa
    16501 tttgatgtcg tcgtgctttc aggtgatcgg gatttgactc aattagctag taaagaagta
    16561 aaagtggata tcactgtaaa aggtgtcagc gatatcgaaa gctatacacc agaacatgta
    16621 gcggaaaaat atgatgggtt gacgccaaaa cagattattg acatgaaggg actagccgga
    16681 gatgcctctg acaatatccc cggtgtgact aaaatcggtg aaaaaacagc tatcaagcta
    16741 ttgaaacaat atggctcagt cgaaggaatt tatgaacata tcgatgaaat gaagcaaagc
    16801 aaaatgaaag aaaatctgat aaatgacaaa gagcaggctt tcttatcgaa aaaattggcg
    16861 accatcaata cttcagcgcc tgtggatgtc tctatcgact cattgaagta tgaagggaaa
    16921 aatctcgata aactcgttcc gttttataaa gaaatggatt tcaatcagtt cctttctaaa
    16981 ttgaatatcg tagaagaaga agtaaaaatg gatgatattt tgtttgaagt cgttcatgaa
    17041 ttcaaagagg aaatgtttac tacggatatg gcgttgtacg tggaaatgat gggcgacaat
    17101 tatcatacag aggaaatcgt cggagtagcg tgggggacag aaaagaaaat ttatgtcacg
    17161 aacgatctat ctgtattcga aaaccgagcg ttccattctt ggatcactga tccgactcgg
    17221 ctgaaaaaag tatatgatgc gaaacgaact tatgttgctt taaaccgcta tactggaaaa
    17281 acgaaaggaa tcgattttga tgtcttgcta ggtgcatacc ttctcgatac gaatgaaaaa
    17341 agcacagata tcgaaggaat agctgctcat tacggataca acgatatcca atcagatgaa
    17401 gctgtatacg gcaaaggggc gaaaaaaggt ttaccagaag aagaggaact cttttttgct
    17461 catttagcgc gaaaagtagc tgcaatcaat gcgttgacac caaaattgag ccaagaactg
    17521 gcagaaaaaa accaagaaga tcttttccgg aaaatggaac tgccattgtc tatcattttg
    17581 gcagagatgg aaataagcgg gatcaaagta gatgcgactc gcttacaaga aatgaagggc
    17641 gagttctctg ctcgcttaag agagatcgaa caaaaaatct acgaagaagc cggcgaagaa
    17701 ttcaatttga attcaccaaa gcaattagga gtgatcttat ttgaaaaaat gggattaccc
    17761 gttatcaaaa aaacaaaaac tggatattcc acagccgtag atgtactgga acagcttcgt
    17821 gaacaagcac caatcgtaga ggatatcctc acctatcgtc aaattgcaaa aattcaatct
    17881 acctatgtcg agggactgct gaaagtgatc caatcagatg gaaaagtgca tacccgttat
    17941 gtccagacat tgacccaaac aggacgatta agctctgttg atcctaattt gcagaacatc
    18001 ccgattcgat tagatgaagg gagaaagata cgtcaggcat ttgttcctag agaaaaagac
    18061 tggctgattt attcttctga ctattcacaa atcgagttac gcgtacttgc gcatatctca
    18121 aatgatgaac atttgaaagc tgccttccta gaaggtcaag atatccatgc cagcacagcg
    18181 atgcgtgtat ttggaatcga aaaggcagag gatgtcacac caaatatgcg taggcaggca
    18241 aaagcagtga attttggtat cgtgtatggc atctctgatt acggactttc acaaaatcta
    18301 ggaatcagcc gaaaagcagc acagcaatac atcgatacgt actttgaaaa atacccaggt
    18361 gtcaaagaat atatggaaag aatcgtacgc gaagcaaaag accaaggcta cgtcgaaacg
    18421 ctgtatcacc gccgtcgata tctgccagac atcaattcaa gaaattacaa tatccgttct
    18481 tttgcggaac gaacagctat caatacacca atccaaggaa gtgctgctga tattttgaaa
    18541 atcgcgatga tcgaattgga taaacgatta aaagaaacag gtcttcaagc tacgatgctg
    18601 ttacaagttc atgatgaact tgtcttcgag gtaccggaaa aagaacttga atcattagat
    18661 aaattggtga aggaagttat ggaacaagct gtttctcttc atgtaccact gatcactgac
    18721 agcagttggg gaaaaacgtg gtacgaagca aaataaacat tgtttaagac agagcaatat
    18781 aatgaaggtg aaaagaaaaa atgccagaat taccagaagt agaaaccgtt cgtaaaggat
    18841 tggaacggtt agtagtagga aaaacgattc aaaaagttca ggtcttgtgg cccaagatca
    18901 tcgagcaacc agagacaccc atctttgagg cttctcttgt tggcgaaacc atccaatcca
    18961 ttggacgtag agggaagttt ttaatttttc atctcgatca ttgtgaactg atctcacact
    19021 tgcgaatgga aggaaaatat caatttacga aagaaaatac accaatcgat aaacatacgc
    19081 atgtactttt cttttttgag gatggaagcc aacttcgcta caacgatgta cgaaaatttg
    19141 gtcgtatgac aatcgtcgaa aaaggagcaa gtgcaactta ccgaggaatc atgaaattgg
    19201 gacctgagcc tttgccagat agcttcttat tagcagattt cgcaaatgga ctgaaaaagt
    19261 cccacaaagc aatcaagcca ttgctgctag accaacgtct agtgactggt ctaggtaata
    19321 tttatgtaga tgaagcatta tgggaagcga agatccatcc agaacaaccg gcgaacacac
    19381 tgcgccccaa agaggtagaa caattacgtc tatcgatcat tgatgttttg gatcgtgcaa
    19441 tagaagccgg aggtaccacg attcgcagtt atttgaatgc attaggagaa tcaggcggat
    19501 ttcaagtagc actgcatgtc tatcagcaaa ctggcaaacc atgtatacgt tgtggaacgc
    19561 cgatcgtgaa aacaaaagtg gcacaaaggg ggacgcacta ttgtccgaat tgtcaaaggc
    19621 taaaaatcgc aaagtaggat ttgttttagg tttgacgggt ggaatagcta ccggtaaaag
    19681 tacggcagcc aaagtctttc agtctcatgg atttcctttg atcgatggcg atgtgattgc
    19741 cagagaaact gttgagcctg gaacgcttgc tctgaggaaa attgtatcag tgtttggcca
    19801 agaggtattg cagcctgatg ggcaactaga tcgagggaaa cttgggatga ttgtttttcc
    19861 atcaaaggaa aaacggcaaa aacttgatca gctattagat ccgtttatcc gaaaagcgat
    19921 aaaagatcaa atcgcctctc taagttccaa tcatccttta gtaattgtag atatcccatt
    19981 gctctacgaa ggtcattatg accactatat ggatgcagta gctgtcgttt atactacgcc
    20041 agaaactcag cttcagcgtt tgatgaaacg taatcaactg acgctagaac aagcgcagca
    20101 gagaattagt agtcaacttc caatcgaaga aaaaaagcag cgtgcggata ttttgttcga
    20161 caacaatgga acaaaagaaa tacttgtggg acaaatcgaa aattggcttt ttgctaatcg
    20221 ctttctttga gtatctgtgt caattttgct atcctgagta tatagaaagt gagggatagc
    20281 gatgggatca ttaaaaaatc aaaaggataa agtcgtaggt aacgcaaaag aaaaaatcgg
    20341 cgagatgctc aataaagaaa atctaatcga tgaaggtcgt acgcaatcag aaacagcaga
    20401 agaaaaagaa aagcagtacc aagcaagaat cgatgaaata gaagaccagc aggcagaaga
    20461 agaagcgaag cggcaagatt tgactcaaga acgaaaaaat ccgacacctg atcgtagtaa
    20521 aacaccgctc ccagaaagtg accacattcc cgatgagcaa aaaatcgagg aacagcgaat
    20581 gaaacactat acaggaatcg aagagaagtt ataaaatagt aaaaaatcga gatgtgactt
    20641 gaagcagatg agaaggtgtt catctgcttc aagttttttg tgctagatga ctaaatcagc
    20701 ttttgtgtaa gttatttctc agtaatcaag gtgatcagta ttggaaaatt gaaatttagt
    20761 aaggacaggg gacacaatta cgcatgaaag tagaaaaaat tgttcttata tccgtgtttt
    20821 ttgggtagga cagtcgcgtt tgtgatttgt ttcgtgttat aatacaacta gttgtaaaga
    20881 aagacacatc ctttatataa aatgcgatgc aagaggtgag acaaaatgag atgtcccaga
    20941 tgtcaacata ataattcacg agtaatcgac agccgtcaag cagatgatgg acgtgcgatc
    21001 cgtcgccgtc gcgaatgtga gaattgttcg ttccgattca ctacatttga acgaattgaa
    21061 gctgctccgt tattagtaat caagaaaaac ggggaacgcg aagagttcaa tcgcgataaa
    21121 attttaagag gactcatccg ttcagcagaa aaaagacctg tagctatgga acaaatggaa
    21181 caaatcgtca accatgtcga aaaccgcgta cgcagtctcg gagaaaacga agtatcgacg
    21241 aatctaattg gtgaatatgt gatggaagat ttagttgatt tagacgaaat cgcttatatt
    21301 cgttttgcaa gtgtttatcg ccagttcaaa gatatgtctg ttttcttaaa agagttgcaa
    21361 gatatcgtgg ataaagcaaa agaaaataat aaagagaata ataaagaaaa caattaagaa
    21421 acaaaaagga ggcatttcct tggaaaatgc ttggaaagag cttcaaccaa aaaatattta
    21481 ccaaggaaga aaagcggctc cgctgagaga agacagcaag aacgccttgc tgtatcttta
    21541 tcagccacta atcggcggag aagccttgag tatctatttc accctgttat cagaaatctc
    21601 tcaagaatct ggcaaaggtc ctgaagggat gcatgcagat ctgcttagta gtctaggctg
    21661 cggtatcccg caattttatg atgcaagaaa aaagctagaa ggaatcggct tactggatgt
    21721 ttattttaaa gaagatagtg atctgggacc tcgttttatt tatgagctgt tagaaccact
    21781 cattcctaaa gcatttttca aagactctgt tctggctttt cttcttctgg aaaaagttgg
    21841 tgaacgacga ttccagaagc ttacccaatt ctttgaacct aaaaggcata cagcagaggg
    21901 atatcaaaaa atcacaaaaa aatttttaga tgtttatcgc ttcaatgaag cagtgtacgc
    21961 tgctaatcaa gaaaacatcg aatcgctgaa taaatctttt gaagaatctg aatcagtagc
    22021 attacttgaa gcagattcga cattcgattg gcagtttttg aatgattggc tggcaaaaaa
    22081 acatattgca agtcttgatg atccaatcat caaacaagtc gacatgtatc atcagcttta
    22141 cggtttcgat gaattgacac ttggcgaact gatcagtcaa tcttatgact ttagtgaaca
    22201 aaaagtatct gaaaaagaac tgcaaaaagc cattttggca atgcagagac gtccggtgaa
    22261 gcaaacaaaa gaaacagttg cggtttctga aaacagtaat gaaccctcgt caaacgaaca
    22321 tttgacaaac gcagcgcttc agctgataaa agaagcacag agcattccac cgatgaaata
    22381 tctggaagca atcaagtcag aaaaaggcgg atatgtttct aaacaagaaa actggttact
    22441 gcaagatctt gtttctcaat caggtctttc cagtagcgtg atcaatgttt tgctgaatta
    22501 tgtactagtg atcaagaata atgctagctt aaatgccagt tatgtaaata cagtggcaaa
    22561 tgaatgggca caaaagaaaa tcgccacagc agaagaagcg atccagcaca ttcggcaaat
    22621 aagtaatcaa gcaaaacaat caaaacaaaa gaagcaaaca aattatcaaa ctggcaagcg
    22681 aaatgttcga cgggaaaagc ttcctgattg ggtcaaccag ccaaaagatg aaaaacagat
    22741 cagcagcgag aaaaaagcag agattgaccg ccgttttaaa gaatacctgg caaaaaagga
    22801 gggtgatatc tagtggaaga cgtaggcaaa gaattgaaga ggatcatcag caaacgcaat
    22861 tatcaagaaa agtatgctga aatgatcgct gaagtcttaa atgatgcgga tgttcaagct
    22921 tttctaagcg cacaccaaga agaattgaca caagcggata ttgaaaaaag ttacgctaaa
    22981 ttgtatgaat tcgtgcaaga aaagcgtaaa tatcaaaaaa acgatccaac gatgatcgct
    23041 cccggctatg agccgaagct gacgttgaat tttcattatg tggatgtcac ttatgtacca
    23101 acggaagcat tgttagcacg gcaaagacaa gaagaaatca gaagccgagt aaaagcaatg
    23161 gatatgccaa aagatattca atcggcttct tttgaaaact ttgaacgtac agatggacga
    23221 ggatatgcga gcttagaagc cctagatttt gtagagaaat atactgctga tccaaaaggg
    23281 tatcataaag gactgtatct agtaggaagt tttggtattg gaaaaacata tttattagga
    23341 gcaacagcga gagaattagc gattgctgga ttcaccacga cgctagtcca ttttccgaca
    23401 tttgccgttg agatgaaaca ggcaatcgga aaagatcaag tggcagaaaa gttagatgca
    23461 gtgaaacgtt cacctatttt gatgatcgat gacattggtg cagatgcgat gagtagttgg
    23521 atacgagacg aagtattcgg tgttatcctt caatatcgga tgcaggaaca gttaccaacc
    23581 ttcttctcat cgaattttac aatggatgaa ttggaacagc atttgtccgt cactcaacgt
    23641 ggagatgaag agccgctaaa agcgaaacgg ataatggaac gcatacgtta tttgacaaaa
    23701 gaaatcgaaa tgactggtcg caaccgacgc aatggttgaa cagttgacaa gtccaactga
    23761 catttgacct agtagtaaaa gcaggtcagc gaatcattat atggacagaa atgaccggag
    23821 acaatcaccg caacaagtaa tgcagaaact taaacggagg attttttatg agggctattt
    23881 tttctagtat atctgtagtt ggtctatttt ttcttttagc aggctgcggt agcgcagata
    23941 gcaacacagg ttctgttgat tcgattgatg cgggtcaaac agtaaaaaca agcagtacga
    24001 aaacggagag acaaagcata tttgtcggaa cgattgaaag tatcactcaa gtagaagcag
    24061 aagaagaaac gcttcagttg aaactcgtcg atgtcatggc caaagaagat ccagcgaata
    24121 tgggaacgtc attcagcaat gacggagtga tcttaaatgc tactgctgaa aaaataagcg
    24181 tggacataaa tgaattgaaa atcggtgaca aagtccaatt tacattagtt gagatgccga
    24241 tcatgacgat gtctatccca ccgcaagttc ctggagattc gattattgat gtttcattga
    24301 acaaataacc aataacattt tttcaaaaat aagaaaatgt tgttttatag aacgaaaagg
    24361 tatatttttt aaggagatat gggaattttt ttattcctag tctccttatt ttatttggaa
    24421 aatgctataa ttatctagaa ggagtgaagc tatgaaccat ttagatttat ctcagcgctt
    24481 agccgcagtg ggtgactttg tccctgaatc cgctcgttta gcagacattg gatcagatca
    24541 cgcttactta cccgttgcat tgatattaag aggaaaaatc gaatatgcag ttgctggtga
    24601 agtcgttcaa ggtccttatg aatcagcacg taagcaagtc aaaaaagatg gattagaaga
    24661 ccgtatcacc gtacgccttg caaatggtct agatgctatc cagccacaag atggtattac
    24721 agctgtcacg attgcgggta tgggaggttc actgatccga gatatcctag aagctggcaa
    24781 gttgaatcaa cgcttaagcg gacaagaacg tttgatcctt cagccaaaca tcggagagcg
    24841 tacattacga tcttggctgc aagaaaatca gtataaaatc caatcagaaa aaatacttga
    24901 agaaaataaa aaaatatatg aaatcattgt agccgaaaaa gaacaaaaac cagttactta
    24961 caatgaaatg gagctgatgt tcgggccatt tctgcttgaa gagaaaagtg agatcttcaa
    25021 atcaaaatgg acaagagagc ttcaacaaag aaaagctatc cgtgaacagc tcaaacaagc
    25081 agctaatcaa gaggcacgtc aaaaacaaat cgagcaggaa atccaaatga ttgaggaggt
    25141 tttaaagcca tgacaatcag cggacgcact ttcatccaaa agtttgaaag ctattgtcct
    25201 cagtggctag ctgaagaagg agacccagtc ggactgcata tcggaacatt ggataagcca
    25261 atccaacgag taatgatgac attagacgtt cgtccagaag tggtcgaaga agcaatcaag
    25321 aaaaaaatcg atttgctgat tgctaaacat cctccaatct ttcgtcctgt aaaacggctg
    25381 gttactgatc agccacaaga aaaaatgtat gcagatttgt tgaaacatga tattgccgtc
    25441 tatgcagcac acacgaacat ggatattatt tgggatggac tgaatgactg gttttgtgaa
    25501 cttctcggta ttgaagtgga gagttattta gtaaagactc atgagattca ttataaaaaa
    25561 ctggccgttt atgtacctgt ggatcatgca cagaaaatgc gtgaagtatt agctgcagct
    25621 ggtgctggta cacaaggtga ttataccggt acaagtttta cctcgattgg acacggtcga
    25681 tttactccgg aagctggtgc acaaccagcg attgggaaag tagggaagac agaacaagtt
    25741 caagaggcaa aagttgaggt tattttgccg gaaactatcg aaaaacaagt gattcaagcc
    25801 atgcggtcag ctcatcctta tgaggaacct gcttatgatc ttttcgctat agatgaacca
    25861 gtcgaaatgt ttgggttagg acgagtaggt gaattgccgc aagaaatttc tatagaggca
    25921 tttgtagaac aagtaaaaga agcgttccaa ctagatggac tgagaatagt ccagccaaaa
    25981 aatgcaaaat cctctgtgaa gcgcattgcg atttgcggtg gaagcggtga aaaattttat
    26041 ccgcaagcaa tcgcccaaag agcagatgtc tatatcacgg gagatatcta ttatcatacg
    26101 gctcatgata tgcaaagcgc tgggttgatt gcaattgatc ccggtcatta tattgaatcg
    26161 ttatgcaagc aacgatttat cgagaaattt gaatcttgga aacaagaaga aaattgggat
    26221 attaactttt tcgtttctga aacaaataca aacccatttc aatttaatta aaaggagaga
    26281 atactatgta cgaaaatctt ttgccacgtt ttttacgata tgtcaaaaca gaaacacgct
    26341 ccgatgcaac aagcaaaacg actccatcga ctcagacaca agttgctttt gcgcaagaat
    26401 tgaaaaaaga attagaagag ttaggcttag ctgatgtttt ctataatgaa gataacggat
    26461 tcgttatggg aacattacca agcaatgttg atcatgaagt gcgttccatt ggatttattt
    26521 cccacatgga tacagcagat tttaatgcag taggagtcaa tccacaaatc attgaaaact
    26581 atgatggcga gtctacgatc gtactagatg cggaagaacg ctatacattg aatacaaaag
    26641 attttccaaa tttgaaaaat tatgaaggcc acacattgat cacaacagat ggcagtacat
    26701 tactgggagc agatgacaaa tcagggattg cggaaatcat gactgcaatg gagatcttga
    26761 tcaataatcc ttctatccct cacggtacca tcaaagtggc ttttggtcct gatgaagaaa
    26821 tcggtgtcgg agcggataaa ttcgatgttg agcaattcga tgtagatttt gcttatacag
    26881 tcgatggtgg tcctttaggt gagttgcagt atgaaacgtt tagtgctgct caagcaaata
    26941 ttacgatcca agggaaaaat gtacatccag ggacggcaaa agatacaatg atcaatgctc
    27001 tacagttagc aatcgatttt cataatcagc ttccagccga tgaagttcca gaaaaaacgg
    27061 aaggatacga aggtttcttc catttgatgg cattggatgg gaatcctgaa gaagcttcta
    27121 tgagttatat cattcgcgat catgatcgtg aaaaattcga agcacgcaaa gcacaaatca
    27181 cacatatcca agaagagttg aatcagcgat ttgatcaaga acgaatcaaa gtagatatgt
    27241 atgatcaata ttacaacatg aaagaaatca ttgaaaaaga tatgagcatc gtggaattag
    27301 cgaaacaagc aatgatcgag cttggtatct ctccagtgat cgaaccagtt cgtggaggaa
    27361 cagatggttc aaaaatctct tacatgggta ttccgacgcc aaatctattt gccggaggag
    27421 aaaatatgca cggacgattc gaatttgttt ctttacaagt aatggaaaaa gcaacagacg
    27481 tgattgtaaa aattgcagaa ttgaacacaa agagttaaaa tcgaaaaaga acagcttatg
    27541 acaaggcgtt cgtcccaatg atggaatgtc atctgtctaa ggctaaaggg caggacaatg
    27601 gaattggttg tcccgccctc ttttttgaag agtaaatagg aggtaaagaa tggaaaagct
    27661 gctagttttt tataacaaaa gttcagggaa agatgagggt gagaaattag cacgctggtt
    27721 tcaagattat gtaaaagaaa agcagccaga attatatgta gaactagctg aaactggccc
    27781 atcgattgat gatgcggaat tagtcaagaa agcagaagcc atagaagctg atactttagt
    27841 aattataggt ggagacggca cgattcatca tatcgtccaa gcgttccaaa aaacattatc
    27901 tcaataccat gtcggattac ttccaggtgg aactgtcaac aaccttgcac gtgttcttga
    27961 gattcccctc aaaaaagaag aagctgctga cgtgatcctg gaaggcaatg tacggaaaat
    28021 agactatggt caagtcaatg atgaagtcat tatctctaca ctgacaatcg gaatcttagc
    28081 agatacagca gtttggatca gtcaagaaga aaaacagcgt tacggctcgt ggatctttat
    28141 caagaagttt tttaagttat tgctgaagaa gaaaaaatat catttggatt tagaaacaga
    28201 cgaggagcat tggaaaggaa aatcccaact gttgacagtc acgatgtcta actccgtggg
    28261 cggttttaca aattttgacg actcagcgac cctagatgat ggaaaatttc atgtaacgat
    28321 cgtaccttcc ttagatattt tccgatttat tttttatttg cctagaatca tgagaggcaa
    28381 attctatacg atccccggca ttacttattt cacagccaaa cgcatgaaaa tccaagcgca
    28441 ggaaaaatct gtgggcactc gaacggatgg agacacgaca gatgatcttc cagttgaatt
    28501 atctgttgta tcaaaaggat taacagttta ttcaccaaag aaagaagaaa aagcttagaa
    28561 atagtagtta acagaaagtt ggaagaagag taatggatgt attgttacac aatcctttgt
    28621 ggttttacct tttcattgtg aatttttact tattttgtct gatggggtat gataaacatc
    28681 aggctagaac tagcggctgg cgtgttcctg agaataattt gatatttgtc agcctgttag
    28741 gcggtggttt gggaggattg atctctcgaa aagttttcca tcataaaact cggaaaaaga
    28801 agtttactat aggattcgct gcaggtgtac ttgttgattt gattctcatt tattttttcc
    28861 attaaggagc aggagatgtc gtctaaagga acgaaaacta aaatcattct gaatctgctt
    28921 ttgctgattg tgatttttgc cattatttat tatttaatca atcaatcatt tgcagatatc
    28981 tttgccgaat tgctgtctac cagtgttgtt gttttggcag cggctgttat attagggaca
    29041 gtttaccaaa tcgctgaagg gcgctcaatc aaagaaattg ctgaaccttt cgcgccgaat
    29101 tttacaacga aagatgggtt cttgacctct agctatattg cgttttaccg aatcgtttcg
    29161 tttggtacag gaacgctgat ctcggagatt tatttttata acaaaaaagg aatgaagcta
    29221 tcccagggag caggggtgac agcactccat atgattatgt acaaactggc agtgatcact
    29281 tatgcattag ctggcttggt catccaattc tctctttttt attctaatgg tccatcaatg
    29341 atctggttta tcatcgctgg tatccttttg acgatcgtga ttgttgcctt tttattggcg
    29401 atgtccgtca gcttgaatgt tcaaatattt tttgtcagct tatcgaataa gttatttaaa
    29461 agtgagcgtt tgcggaaatg ggtggataca tgcaatcagc agatctactc tttaagggaa
    29521 acggtccaaa ccattatcca agacaggact gcgctattgc ggatttatct atggaatatg
    29581 ttaaaacttg tattttggta tgtacttcct tatttgattc tgattgaaaa ccatcctaaa
    29641 atagattttc tactgaccat ttcgtttatc agctttgcag tagtgctttc aggggttatt
    29701 cctacgcctg ctggtattgg ttcctttgaa tttgtctatt tgttattatt cagaccagtt
    29761 gttggaacag ttgacgcagt ttcttcgctt ttactgtatc gtttcagttc ctttatcttg
    29821 ccatttctct atggatttgt gtatgtgatt gctgaacggc gaagagtgat caaagaagaa
    29881 ataatagaag taaaaaaaga gaataaagaa aatcaagggt aggtctttta taagatctac
    29941 cctttttatc aaatcaaaga aaaacgttat ggataagata attttacgtt tgtttggctc
    30001 tttttttata tacatacaat caattttgtt tttttaagat ttatataagt cgagaaaaaa
    30061 agtcaaaaaa ctatgtgtat attttgacca aaattgacca aagcgatata atagtttttg
    30121 taaagatcaa agaaataagt gatcttacct ttaattagga gggtatacct gtatgaatat
    30181 tgagaaaatg actacgacgc ttcaagaagc gattgctgaa gctcaacaga ttgcggtcac
    30241 tcgaaaacat caagatatcg acattgccca tgtatggaaa atctttttac aatctaatca
    30301 ttttggtcga aatttctata cggatgccgg attggatgtc gaatcttttg aacatgaaat
    30361 tgatcgtcta ctggatgagt atccagttgt ttctggtgga aacgtccaat atggacaaaa
    30421 cctcagccag aatttctttc gattattgaa tgaagcagac caaatacgtg aaagcttcgg
    30481 cgacgagttt ctttcaacgg aagtcgttat tttagcgttg atgaaattaa aaaattatcc
    30541 gttaactgtt tatttgaata aaaacggatt atctgaaaaa gaattgcgta aaaacatcga
    30601 agagatgaga ggaggagaaa gagtgacctc acaaaaccaa gaagaacaat acaaagcatt
    30661 agaaaaatac ggcgttgatt tagtacagca agtcaaaagc ggaaaaatgg atccaatcat
    30721 cggtcgtgat gaagaaatcc gtgatgtcat ccgtattctt tcacgaaaaa caaaaaataa
    30781 tcctgttctg ataggagaac ccggtgtagg gaaaacggca atcgttgaag ggcttgctca
    30841 acgtatcgta cgcaaagatg tgcctgaaaa tttaaaagat aaaacgattt tttcattaga
    30901 tatgggtgca ttgatcgctg gagcaaaatt ccgtggtgaa tttgaagaaa gactaaaagc
    30961 agtcttgaaa gaagtcaaaa aaagtgatgg acgtatcctc ttgttcatcg atgaaatcca
    31021 caatatcgta ggggcaggaa aaacagaagg aagtatggat gccggaaatc tgttgaaacc
    31081 aatgcttgct cgcggtgaat tacatttgat cggtgccaca actttagatg agtaccgtca
    31141 atatatggaa aaagacaaag cgttggaacg tcgctttcaa aaggtattag tcaaagaacc
    31201 aacagtggaa gatacgatca gtattctgcg tggattaaaa gaacgttttg agatccacca
    31261 tggtgttaac atccatgaca acgcattagt agcagcagct actttatctg accgttatat
    31321 tactgatcgg ttcttaccgg acaaagcaat cgatttgatc gatgaagcca gtgcaacgat
    31381 tcgggtagaa atgaactcta tgccaacgga attagatcaa gttactagac gtttgatgca
    31441 gttggaaatc gaagaagctg cactgaaaaa agaatcagat gatgcaagta aaaaacgctt
    31501 gaaaaatttg caagaagaat tagctgaact tcgtgaagaa gcaaatgcga tgaagatgca
    31561 gtgggaaaca gaaaaagaag aagtcaattc tgtttcagca aaacgtgctg aaatcgataa
    31621 agcaaaacac gaattagaag atgcagaaaa taactatgat ttagaacgcg ctgctgtatt
    31681 gcgtcatggt acgatacctc aattagaaaa agaattgaag gaattagaag ctaaagcaaa
    31741 agacagcgag attaagatgg ttcaagagtc cgttaccgaa aatgagattg ctcaagtcgt
    31801 tggcagatta acgggtatcc ccgtaacgaa acttgtagaa ggtgaacgag aaaaactaat
    31861 taaattgaat gaaacacttc ataaacgagt gattggtcaa gatgaagcag ttgatgcggt
    31921 cagtgacgcg gtaattcgtt cacgggctgg attgcaagac ccaaatcgtc ctctaggttc
    31981 tttccttttc ctaggaccaa ctggtgtcgg aaaaaccgaa ttagcgaaag cgttagctga
    32041 gaacttgttt gactcagaag atcatatggt acggatcgat atgagtgaat atatggaaaa
    32101 acatgctgtg tctcgtctag tcggagctcc tccaggctat gtaggttacg aagaaggtgg
    32161 tcaattaacg gaagctgtca gacgaaatcc ttatacaatc gtcttgttgg atgaaatcga
    32221 aaaagcgcat cccgatgtct tcaatatctt gttacaagtc ctagatgacg gacgcttgac
    32281 tgattcaaaa gggcgagtag tagatttcaa aaatacggtt ctgatcatga ccagcaatat
    32341 cggttcacag ttactgctgg aaggcgtgac tgctgatgga acgattccag aagcagtggc
    32401 tgaacaagtc aacacgctat tacgtggaaa cttcaaacca gaattcttga accgaatcga
    32461 cgacacgatt ttatttacac cattgagcct agacaacgtg aaaggaatcg ttgacaaaat
    32521 ggtggcgcaa ttggcacaac gtctggaaca tcaagaaatc ctgctgacaa tcagtgatga
    32581 agccaaaacg tggattgctg aaaatgctta tgaaccagca tatggtgcaa gaccattgaa
    32641 acgatttatc actaaggaag tagaaacacc actagctaaa gaaatcgttg caggacatgt
    32701 tatgcctaaa tcaaaagtaa cgattacttt acttgatgga caacttcatt tcaaaacaga
    32761 agagctagaa gaaatcgtct aatcttccat tgagactata aaagaaaaaa ggggtctgac
    32821 acaactagtg tcagacctcc ttttttcaaa taaacagtgt tccagaagta gtttcttcga
    32881 aaaataagcc gaaatttctt gaagctgccc gcttctgtca caacctcttt tattaggtat
    32941 ttttcacttt ttctaattta taactttcaa agtaacgctc atctttttta ctttgagacc
    33001 atgcaaacaa tcccattaag gcagcaccta tcgtatttgt cagcaagtcg cccatcgtat
    33061 ccatcaatgc tgctcgtccg acaaacagtg tgccatcaga agcagcaaaa cgttgaagat
    33121 tcatgcctaa gaactggtcg cataagaatt cccagaactc ccaaaacacg ccgcaaagtc
    33181 cagcaaacgc aaagccgaat aagaggaaca accaaggact ggtttttgat atctcagcat
    33241 ctttcatcaa gtaaccaatc aatccatagc caagagctgt caggaccatt ggactcaccg
    33301 catgtaagat tttgtcccaa aaagagatga tactgatcaa atgcatccct gtgcctaaaa
    33361 agacagagat gaacaagaaa aaccagtaaa acaaaacgat tgctgctggt attttaagtt
    33421 tgaaaacttt caaaatgact tgtggcatga aaatcaatgc aatccctaat aaagattcca
    33481 cgataaatgt gattccttga gaagtcgaat atttttgtgt gataaattca taaaaattat
    33541 agcagacaac gaatacacca aaagcaagta aagctatttg cacctttttg atttctttaa
    33601 tcactgaaag tccctccatc taaaaatctt tttacttctg aaagcaactc aatttctgaa
    33661 gaaaccactt ttccgttcaa tttgatcaaa cctattgtat ataagttcag gtagtgaaat
    33721 tgattttcag ctgtttcttg tagtgcagcg atttttttcg ggtgggttcc gccttgctgt
    33781 cgagtatcag tatataagcc gatcactggg atgcctttcg cataagccac accgatttcc
    33841 gatgctaccc cggcatcgat cgtcagccca tctagtaaag caatcattaa atcactagcc
    33901 aacacttttt ctgtgtcagc aagagcaatc attcgactgt ctgcataagc agttttgtca
    33961 ttgattgctt cattttcttg aggaagatag atcgaaagct cagaagagag ctctctgatt
    34021 tctttaacta actgttggtt atataacaaa tcacttttag caaacattgg tgcggcaaaa
    34081 taaattttca tctaaacatc atccttttta tcaaaaataa tcgctaaagt aagcttccat
    34141 gtttggaatg atacgctcta gtgacttcag tgtttcttca tctgtttcta accgttcgat
    34201 tcttgccaaa taagaagcac ggcgataatt catcatcaag caagtcaatg tttggatatc
    34261 cagtcgaacg gattttccta taggttcatt taagacacgg acttgtccct gttcatccca
    34321 tgttaaagcg aagacaccat tattccaagg agcgacagga tcttcaatga tgaaatgaaa
    34381 agcatcagct gttccaacaa acggaaaccg ttgaaggaat tcttttacat caacgatccg
    34441 agccataaaa tatggttcga tctgctcttt gatctgacta tcttcaatca aaaatgctaa
    34501 aggctcattt ttataaatat ctccatgtac ccagtagatc atggaaaaat gtgcggaaat
    34561 aaagttccat aagccatttc gagcttcttg atcaagatag aacatttctt ttacgtgaaa
    34621 tatttcttca gctacccagt agaacagaac acctcttggt tcatggttgc tatcgtagta
    34681 gacagcggct gtgcgctcat cttcattttc gaaacgccaa tactcttccc aatgaaaatc
    34741 actgcggaat aaagcaccat ggttttgttg ggcaaatttg tcataaacgg aaaatacgtc
    34801 tggatgatca actggtaatc gctcaaccat accacttact gggatttgtt taggtagctg
    34861 tgtatctctg attttaaagg aaagtttatc agacatgatt tcccatcctt tacgccgata
    34921 gtaggggata ctgtaaggat acaaataaga gatccattgc ttattcttgc gcatattatc
    34981 caatgcaacg ataattagat cttgcatcaa tccatggtta gcatattctg gataagttcc
    35041 aactccagtc acaccaccca ttttataacg tgcaccgtga atattgactt cacaaggata
    35101 gatagcgatt tgagagatca gtttattttc gtggaaccat ccgaacactt tcgatacttc
    35161 caaaatcggt tttttggaac ggataaaagc tcgtttattc tcaaacccgc tttcctcgat
    35221 gtctgcttca gtcacttgga acacatagga aagcaattca ttgaattgat cgatatgttc
    35281 ttgagtgacc ggttttaatt caagattttc tctaaaatct ttttgatcca ttttttcatc
    35341 tccatttatt agcttgataa cagtatagca aaattctaca aaaaaaactt ctatagctga
    35401 ctaattaaaa actctttaaa ttactgcttt tcgttggtat aatggaaagt gctgattata
    35461 tgaaaagagg agacgctatg gatataaaga aaatgaaaga acgccaagag cagattcgta
    35521 atttttcgat catcgctcat atcgaccatg ggaaatctac attggccgat cgtattttag
    35581 aaatgacgca cactgtgacg tctcgcgaaa tgcaagatca gctgttagac tcgatggatt
    35641 tggaacgtga acgtggaatc acgattaaat taaatgctgt agaactcaat tacacagcga
    35701 aaaatggaga aacatatatc tttcacttga ttgacacccc agggcacgtc gacttcacct
    35761 atgaagtctc tcgaagcctt gctgcctgtg agggtgccgt tttagtggtc gatgcagcac
    35821 aaggaatcga agcacaaaca ttggccaatg tttatttagc gttagacaat gatttggaga
    35881 tcctgccagt catcaataaa atcgacctac ccgcagcaga tcccgaacgt gtccgtcaag
    35941 aaatcgaaga cgtaatcgga atcgatgcta gtgaagctgt attagccagt gccaaatcag
    36001 ggattgggat tgaagatatt ctcgagcaga tcgtggaata tgttcctgca ccaagtggag
    36061 acttagatgc accgctaaaa gctttgatct ttgactctat ttatgatagt taccgcggtg
    36121 ttgttctaaa tgtccggatc acggacggta tggtcaaacc cggagacaaa atcaaactga
    36181 tgagtaatgg caaaacattt gatgttacag aggtcggggt cttctcgcca aaagcagttg
    36241 ctagagactt tttgatggtc ggtgatgtcg gttatatcac agcaagtatc aaaactgtcc
    36301 aagatacacg agtaggggat acagtaacgt tagcagacaa tcctgccgct gaagctttac
    36361 caggttaccg aaaaatgaat ccgatggttt attgtggtct ttatccaatt gatacttctc
    36421 gttacaacga tttgcgggaa gctttagaaa aactgcaatt gaatgatgct gctttacaat
    36481 tcgaaccaga aacctctcaa gcattaggtt ttgggttccg ctgtggattc ctcggacttc
    36541 ttcatatgga tgtcgtccaa gaacgcttgg aacgggaatt caatctagaa ttgatcacga
    36601 ctgcaccatc cgttatttac catgttaata aaacggatgg tacgactgct acagtagata
    36661 acccggcaga ttttcctgaa cctgtaacga ttcaggatgt agaagaacca ttcgtcaaag
    36721 cacagatcat ggtcccaaat gattttgtcg gtgcagtaat ggaactttct caacgaaaac
    36781 ggggagaatt cattacgatg gattatttag atgattaccg agtaaatgtc gtctataata
    36841 ttccgctttc tgaaattgtc tttgactttt tcgacaaatt gaaatcaagc acgaaaggct
    36901 atgcctcatt ggattatgaa atgtctggtt atcaaaaaag caagttagtg aagatggaca
    36961 tcttgctgaa tggagaaaaa gtcgatgcat taagctttat cgttcaccga gactttgcct
    37021 atgaacgtgg aaaagcaatc gttgaaaaac tgaaaaaact aatcccacgc caacaatttg
    37081 aggtgccaat ccaagcagct attggacaaa aaatcgttgc ccgttcagac atcaaagcct
    37141 tgcgtaaaaa cgtcttggct aaatgttatg gtggagatgt ttctcgtaaa cgtaaactct
    37201 tagagaaaca aaaagaaggg aagaagcgga tgaaacaaat cggctccgtc gaagttccgc
    37261 aagaagcctt catggccgtt ctgaaaatgg atgagcaaga tagtgtgaaa taacttataa
    37321 tcaatcgaaa aacctattaa ataaaccttt ttgagtagat gcaacactga ggattatctg
    37381 tataaaagat tttaaactgt catttggtta tcacggcgat actaaaatta acaaaattgg
    37441 aatatttttc ttgaagattt ttagctgtca gtatatgatg aaagcatctc ataggaggtg
    37501 cttttttcat ggttgataat tcaagtggaa gggttcttaa atctctaaga aaagagaaaa
    37561 aactatctca aaaaaagtta gctgatttag caggtatttc acaaagtact ttagttaaat
    37621 atgaaaaagg gtcaagaaaa atccctaaag acgtagataa tactctaagc aagattctga
    37681 atatagaaac tctaataaaa gatgaggaag ataagattga gattctcatc ggtaaactaa
    37741 ttgcatacag agatatgaat aagttactta acaaagagtt agctgataat ataggaatta
    37801 gtgaagtatt actcagttat gtgttaaata gaaagagaaa tccgtcaaaa gaaatgcaaa
    37861 aaaaaatcga tatttttcta ttaagtaatg aaaaagaaat tttgaaggag attaatcgtg
    37921 atagtgagat atttagttta tcaaaagacg ataaaattgt tatgggaaaa agaatacgag
    37981 aagtccgaaa gaaccgggaa gagacgcttg aaaaatttgg taaaaacttt accatctata
    38041 caggcaaaaa tgttataagt agatgggaaa aaggtattaa tattccagat attgaaaaac
    38101 taatgaatat tgcctatctt ggtaaggtca ctgttcctta ccttatgtac ggagaagatt
    38161 ataagaatat acttccaaaa gatgaaagag ttagcgattt taaaaagata aattctttta
    38221 gtatgggatt aaggatgagg aaaattagga aagattatta tctagaaagg gaggagtttg
    38281 gaaagctttt ttctccttca atttcaaaat ggtccataga taggtatgag aatggtagag
    38341 atatacccaa tactaatcga attatccaat atgcttatat aggaaatctt tctttagaat
    38401 ttttgattta cgggatataa aaatagttta cgtcgatact tattaagtta tcgacgtttt
    38461 ttattataga aaaaatttat aaaaggaggt ttcttgatat gataagaaac aaaaagggtt
    38521 tgttgaaagt tgctttactg gcagcttttt tctaagtaac tttttgacaa gctcaatggc
    38581 aacacaagcg gaagaagtaa tacaagaact aactgttatg aataacagct agataaaatg
    38641 ggctatgtat gttatccaac aatttagtaa tcactagaag cctagcgaaa gttcgcttga
    38701 taagttatag atgagtattg atttgtagtg tttccaaatc aaaagggtac agagccacat
    38761 gaaatatgtt gtcctctgca gcgtcaggat gggaatccat accatggaga ttcggagatc
    38821 tgtgagggaa tacttacgtg gttaatatgt cagttgtgtt ggacgtagta atggtcatag
    38881 tgggtagatt gactgaattc ttatatgaga aaatgaaacc aacaagaaga tagggttatt
    38941 tatacagaat tggggatctt ttctggaaaa gtaatcggat aatgcgagat tcgtacggtc
    39001 ttttttaaat ttctctaaaa aaaacggcat cgaatgggtt gggtgattga taagcaatga
    39061 atcatagact gatatagaat aaaaaatgat tctatttatc tttttacatc tatcgttttt
    39121 tcaagtagcc gcaaattata tcagcattca acaatttttg tatacaagtt ctagtaaaag
    39181 gatctgaaga aaaagttggt tgttgtgaag ataaaaaaag aatcaggttt tactgagttt
    39241 ttcttcaaaa tttgtgttat taggttagga caaagataag aagaagtatg aagatttaaa
    39301 aaaggaatga ggaaaagata gtaatttccg attattggag tttttttatt tataaagaag
    39361 aagcgaataa gttgtgattc ctagatttcg cgcgtgatta attaatgagc aaaaaatgcg
    39421 gaaagtttta gtgtttaata cacgaggaca aagtttctta ggtattgaag gcacacgtgt
    39481 aacggttgat gggtggtgtg attgtttcga ggttggaaaa catgttgaac ttatggcatt
    39541 tactgagcta aaagataaga acaacgtgga atttttcgag agtgatattg gttgggacga
    39601 tcatgaagaa gtttatggaa aatttatttt gcggaaggga aattcttata cgaatgggga
    39661 agcataagta gcgatttgtt agagatcatt gataggattg aaattgtcgg gaatatttat
    39721 gagaatctag agttatttga ggtgatagaa tgagtgatgg ttttgaacaa gtatcaataa
    39781 ttaaaaatca agttcgggag attcttagaa aaaaaggcta tttggtagat agttattttg
    39841 aaggagatta cgaaacatgg gtaggtgtct atgctcgtcc agagaataaa cctacctatt
    39901 tagatcctac gacgtcagaa gatgcctatt tacaaaatag gtatcgagta gatggtttta
    39961 agcaagactt tgcggagtgg tttgaatggg aaattgaaaa cggagaagta aaagaagaat
    40021 aagagtactt gttgtatcaa aataagccag tagaacaacc aaaccagtag ctagtaatga
    40081 caataatact gaggaatcgg atcattatgg tatgattgat atttctcttc cagaagatct
    40141 taagccagat cctgtaacaa ttggcaatag tgtcatgatt tttgattcat tagatgaagc
    40201 tatgtcatat ggttggaaag aaattaagga tgaaggtagt aattggtatg gcatgagatt
    40261 tggtgatggt gaagttgcca aaaaagctgg tattccaatt gggaaatgga cagttgattt
    40321 ccacgaagca ggttcttttt ttgttctgta attatagtgg gagggtaaaa tcattgatga
    40381 aatgtgttca gataagagcg ccagataaaa atagaagaga cagttcacgt cgttatcact
    40441 tttggtaacg gcgttttgtt ttattatata aaattctcag gaaaaggagg aattcttgtg
    40501 tatgcaaaaa cgaaaatgaa ttggttgaaa gcactcgcat tggtggcttt ttctcaattc
    40561 tgtttcttgg tgggaactgc tcaagcacat gcagaagaaa cgacggctat acaacctacg
    40621 atggaagcca ttgcccaagt cgcttctgaa gtgacagaag tccaaccagc agaagccggg
    40681 gtcccagctg gtgaagccac tgttgaacag gcccctgtga cagaagcgcc aacggtcaat
    40741 tccaaaacga ctctcgatca gacgattggg gaaacacaac acccagggaa tagtcctggt
    40801 acttcacaac cagttgaaga aactgcctca attacaaccc ctgcttcaga aacgtccact
    40861 ctagaaggag aaaaagctgc cgaagcaacg ccttctgtgc agccagagtc ttctgagaaa
    40921 caagcggaag aaaagaaacg aatagaagaa acagtggaac aaccagcggc tactgctgac
    40981 aaagaaggaa aaaatgagga aaacgttgaa aaaacaatct cttcaaccgc agctagtcaa
    41041 aatcaaccaa cgaaaccaaa caaagaatct acggctagta ttgaaaatca aaagaaaaaa
    41101 gagcagaaca ttccaaaaac aggtacacct acactgttag taacagtacc aaccaatcgt
    41161 tcggttcgtg ttcgccgtgc aaccaatgca gctgttttag gtggtcggaa aattgattgg
    41221 ggcgaaaata ttggtgttac ttctagtccg aacaatctaa acttcacttt aaattatatg
    41281 gttcgttttg agattaatgg acaagtggcg ttttgtattg agcctggtgt ctcagccgca
    41341 gaaggtcaag tttatacagc tactgctttg aaaaactatt tgaaaaattc aaatgtacgg
    41401 aaaaaaacaa gcttgatctc ttatttagga tatgtcacaa ataaagacaa atccgatgaa
    41461 caatacattg cggcacaatt tatgatttgg gaagctttgg gcacaaaaat cccaatcaaa
    41521 aatatccgtg ttgattatga tcgtcgaaaa gcagaaattc aacgtttgat taataacttt
    41581 ggtgaaaaag caacttttaa taatcaaaca catacggtaa aaattggcga aacgttgaaa
    41641 gtaaagaata aaaatgattt tttgaaatat gtgaaagaca ttcaaaaacc aaaaggtgtc
    41701 aatgtatcta ttcacggcaa tgaagtatgg attacagtca caaaagaggc accggataaa
    41761 gcaaaaattc aattgaataa aattaaagtt caaggtgcgc cattagccta tcgtcgtcca
    41821 ggagctcaaa caattggtgt gttacatcca acagaaccta atgcgtctgt tattaattta
    41881 caaattctaa aacaaggaaa cattcgtgtg tttaaagaag atgcggaaac tggtgtgaaa
    41941 gcacaaggtg cagcttcttt agaaaatgcg gtctatggtt tgtatcaagc agatgggaaa
    42001 aagattaaag aaattacctt gaaaaaaatt aacggcaaag tacaggcaga aattaaagat
    42061 cttgatcctg gcaaatatgt tttaaaagaa atcaaagcgc caaaaggtta tgtgctttct
    42121 gatgaagcaa ttgaaattgt tgttgaacct ggaaaaactg tcaatgcgac cgcaaaagat
    42181 caagtgatca aaggaaccat tgatttagtg aaagttgcta ataaagattt agtcgattca
    42241 acgaatccag ataacaaacc aaaattagct ggcattgaaa tcactttgac gtcaaaaaca
    42301 actggcaaag tggtgaaaac cgttgtgaca gacaatgatg gttatgctac ttttggtaaa
    42361 aataccgttg tctttgatac gtacattctt tctgaaacca aaggaaaaga agggtataaa
    42421 ctatttgaac cacttgaagt cacaatttct gaaaatgggc aaactttcca ttatgtttta
    42481 gaagataaag taattgaaca acgtcttaaa gtggtgaaag tggatcaaga aacaggaaaa
    42541 gtgattccac ttgctaatac agaattcaag atttttgata ctttagccaa tcgttatgtc
    42601 acaatggaga ttccaaatga tacagaaaca acggatatct ttaaaaccaa tgaaaaaggc
    42661 tttttcctaa ctaacggtac acttacttat ggaaaagatc gctatcgttt ggaagaaatc
    42721 aaagcccccg taaattacgt tttgaatcaa aacccattag tgttctcgat taccaatgat
    42781 acagaaccga tcaaagtgat ccattttgcg aaccgtcaag cacggaaaag tgtaaaatta
    42841 ttcaagtatg aagaatggaa caagaagaaa acgccgctcg caggtgtgaa ctttaccttg
    42901 tataacggta aaaatcaagc aattggtgaa tataccactg atcaaaacgg ggaaatttta
    42961 gtgaaaggtc tagttgccga tgactattac ttcttggaaa atgccccatt agaaagtttc
    43021 caaccaaata cagataaaca agcattcacg gttgcattca aacaaaatgc gccagatgat
    43081 ggggaaacgt tagtggtttc tgtacgtaat tacttgattc caccaaaact agaaacacaa
    43141 gcgtcaaata aagccgatgg tgaaaaagtg gttgatccat tagaaacgat cgtcattaaa
    43201 gacagtgttt cttataccaa cttgtttgtc ggaaaagaat acaccatttc aggagtattg
    43261 atgaacaagg caacgaatgc gccaatttta caagatggca aagaaatcac aagtaccttg
    43321 gcctttattg cagacaaagt caatggcaca aaagaccttg aatttgtggt taatgctagt
    43381 gttctgaaag gtcaaacgat cgttgttttt gaaaaacttt tccgtgatgg cattgaagtt
    43441 gcagcacatg cggatatcaa cgatgaagcc caaagtgtga aagtgaataa tccaaccgtt
    43501 cataccacgg ctgtctttga agacggattg acagtcgcag acccaacagg attgtttacc
    43561 ttaaacgata ccgttgaaat taccgagatt cttccaggaa aagcatactt ggtcaaaggg
    43621 atcttaatgg ataaagcaac cggtgaaccc ttgcttgtgc atggaaatac ggtagaaacg
    43681 agtgttggct ttattgccaa agcagaaaat gaaacggtga tcgtaccatt tacctttgat
    43741 ttgacaggta taaatggtcg tgaaatcgtc gtgtttgaaa gtctttttag aaatgatgaa
    43801 gaactagcaa accataaaga catcaacgac aaagggcaaa cggtacgagt aactaaccca
    43861 agtgtacgta caacggctac acataaaccc actggcttga aagaggttaa tccattaacg
    43921 aaagtcacca ttacagacgc tgtgaaatac cacgatttgg tcgttggaaa aacatacaca
    43981 gtcaacggtg ttctaatgga caaagtaacg gaaaaaccag tgctagtaga tggaaaagaa
    44041 gtcacaagta ccttaacgtt tgtggcagaa acaacggatg gtacagtcaa tctagacttt
    44101 attctagacg cacgtgcgtt gcgaggcaaa gaagtcgtgg tctttgaaga tctgtttaga
    44161 gaaggcgtat tattggcttc tcacgcagat attaccgaca atgaccaaac catcaaaatc
    44221 agtaatccaa ccattacgac gaaagcgacg aataaaaatg gcggaaaaga gatcttggcc
    44281 ttgccaaatc aaactgtgct tgaatgggtc aaagtagacg gtcttgcgat tggtcaaatc
    44341 tatcgcttaa ttgttcaagg ctacttaaca ccagacggca caccatttga aggcactcat
    44401 gcggaaaaag tctttgcggc cgataaagaa atgatggaat tcttatttga attcttagtg
    44461 gacggtcgca atcttgcagg aaaaggcttg agttttgcgg aatggctcca agcgaaaacg
    44521 gaagatgaga aagaaacgtt tgaagaagtg gcgaaacaca atgtagatct aacaaacaaa
    44581 gatcaaacgg ttcaaattgt ggaagcgcca aaaccaccgc aaccagtgaa accagaacaa
    44641 cgggttaaac cagctactgt tgtaccaatg ttgccaaaaa caggtgaaca aacaagtagt
    44701 atacttatgg ttcttggatt agtagtatta gtcattgctt taggtataac actttataaa
    44761 gtacgtaaag ccaaagatta gtcatgagga acaagcggtt aggattttta accgcttgtt
    44821 tgattgtaat gtagaaatat ttagaattta ttttggtttt taagaggagg aaaaacttta
    44881 tggcagaaaa agcattgcgt atgaagaaag agtttttagg tcaagtattt ttattgggtt
    44941 cacgggaacc taatccacca aaggaaatta atggtgtgtc tgggcgatat gttcaattac
    45001 aagcagagtg ttcgcgagaa gaacagcctg ctttttttgt ttatctcaca gctgaagagg
    45061 ataaaagatt acgattacca gaaaaagagg tgcgtatttc atttgaagaa gcttattttg
    45121 tttttcgtaa agaacgagtg aatagtcgtg aaacaaatga tatgggacaa acagagcgtc
    45181 gaacaactgg ctatcaagat gttggtgtct ttttaactgg tgtaaaaatt ggggaggttt
    45241 tgtaagatgg gattaaaatt tccaaataat tatgacatta cagaagcatt agatgaaact
    45301 tgtttaggag ccgtacgctt tggcgcatta gaagagtctg atcgtgtatt tgataatgaa
    45361 acaggcgatt atacgggaga aattcgatca cagcgagcac aattagtttt tggaaatcca
    45421 gatgaaccaa agattgcacg acgagttaaa tttccagcag atgtagattt gactggtttt
    45481 aaacgacgtg atcctgtgaa attaattgat ccagaatatc atgtggtata tattccagca
    45541 caagatggca atcgtgaata ttcagattta gtgatttatg cgaaaggatt agagaaagta
    45601 gaagctccaa caaataatcc taatatgaaa caatcacaag aaaaaggttt agatcaaaaa
    45661 caaccaagtg ttgattctaa ggaaaaagag aaaaaataag gtttttttga aagaatagga
    45721 aggagtcttc ctattctttt tatctaagat agaaggaagg ggagattttg aattcagata
    45781 aaaccaatca aatactttga gagattgtgc ttgttatcaa aatatccaac aattgattga
    45841 gtattttgga gacaatccaa cgatttttgt acaaacaaat gcatatattt gtgcggttat
    45901 tgggcagtgt atgtttttac gtgatcttgt tcgtttttca ttaccgtacc agtggaaaca
    45961 agatcatcag gaagtgattt ggattcgtat agtacgaata tgtaatatgt gtgcacaccc
    46021 ttataaaaat cgattaaatc tttttcgatt atgttttttt actaaatgtg atattcctgt
    46081 attagttgct ttttgtcaaa agtttttagc acaggaaaag taaaaacaga aaggaggaat
    46141 gtgacaattg aaagctcatt ttttcaagta tcgtggtcgg cgaattcgct atttcaatcg
    46201 ttatttatgg ttttgctatt atggtttctt tttgtttcca tttttgattc tgttaggttg
    46261 gtttagttgg aaagtatttt atccacgttt aagtacgttt tcgaattggc aaatgtatct
    46321 tattcctgga ataagtattg tgttgtattt gttgctggtt agtgggttaa ttttagggtt
    46381 gatgcattgg tcgcgactaa aagaaggata ttttgcctct gtttattggc gtcagttact
    46441 tgttcgaatg ttaattgaca atcggtttgt ttatacaaag aaacaagtta gtgagaaaca
    46501 aacaagggaa aaaatgagat taccaaaagt ttatttttat caaaagaaac aagaattagt
    46561 ggtttctttt cctttagatg gtgggcgttt tcacgaacga tttttaaaaa tgggtcattt
    46621 gttatctgaa gtatttttgc gtgatttaat tcgtgaagaa cgagaaaaag cccgaatcaa
    46681 ttatgtattc ctttcagatt ctggtcggat tcctattgat caatgtatag cagaaaatgg
    46741 acgtattcat ttaatgaaaa ctttggattg ggtatatgat caatcaccaa atatgttgat
    46801 tgctggtgca atcggtggtg ggaaaaccta tttattgtat tctttaattc aagcttgttt
    46861 aagtgttggg acagtagata tttgcgatgg aaaagcggca gatttagcag cattaggtga
    46921 cgtcgatgta ttcaaaggac atgtgtttta caaaataaat gaagaaatga ttatttgttt
    46981 acgaaatgca ttaaaagaaa tgaatcaacg gtatgcctat atgaaaacca tgaaagatcc
    47041 taaatatgaa ccagggaaaa attatgctta ttatgggtta ccaccgcatt ttatcttttt
    47101 tgatgaatgg gcagcttttt atggttcgtt ggatatggaa gcgagaaata gagtcgataa
    47161 attgattcag ccattagtat taaagggtcg tcaagcaggg atgtacatta ttttagcaat
    47221 gcaacgacca gatgcagaat attttccaag tggtgttcgg gataatttaa cattccgtat
    47281 ttctgttggt cgattgtctc ccattggtta tttaatgact tttggagaag attttaaaaa
    47341 taagccattt tacaacaaag atcaacctgg tcgtggatat gcttttccag gatttgatgt
    47401 acctgtagag ttttttgcgc catttgttta caaagattat cactttatca aagaatttga
    47461 gaaatttact gaaatgattg tctatgattt tacagtaaaa gaggatagtc aagatcaaac
    47521 gatgggagat gataatcagt tgttacaaga acaactagag cgccaaatgt atttagcaaa
    47581 agatccaaaa ggaacaagtt tttctgatgc gcatattttg taatcaacta aggaggtgaa
    47641 gttaaatggc agagagttgt tattatagag tagctacagc aatacgaatg attaatcctt
    47701 ctctttcttc cagaacgttt tatgattggt tgaatcgtat tgaacaagta actgattacc
    47761 gctttttgcg caaagaacgt gtttttacag gaaaagttat taatcaagta ttgctaacga
    47821 aaaaagatat agaacgattg actcgattgt atcattatcg agtagattta gaagaggatt
    47881 taactttgtc aatttatcgc gttttttctc ctgaaaaata tagtgaaata acaaaattag
    47941 atcatttaat tttgtagtta ttatctatcg ggagggctct agacgtagtc tggtagccgc
    48001 actctgcctg gcggtgcgca ttaaggctgc gaagcatggg cctataatgc gcactcgcta
    48061 gcagcgtgtg cagctcacaa agaggtcgtg cgcttgcgca cggcctcttt gtgtaaagcc
    48121 ccccgatata taatatgggg ggcagaaata acataacaca tagaaaaaag ttttataaac
    48181 ccttttgtat caagtgatta tctaaggtca gcagttgtac tacttttccc aaaaaacgag
    48241 ggggactagt tgatatatcg gtgtttctaa agggttaaaa aaatcgattt tgttatttta
    48301 taaaaggagc gagaaaatga caccgattga gctaaaaagc tacagaaaga agttaagtgc
    48361 aattcataat ataagtggag ataaaaagcc gctatcacaa gcaagatttg cgcaattgat
    48421 gggctgctca aaagattaca ttagaaagat ggaacaaggg aaaagaaaaa tcccagagga
    48481 ttttgaacaa cgaatcaagg aacgctttcg attgtatatg aaaagcggaa tagatcttcg
    48541 agcaatgatt gattatttgc gtctttcctt ttttgggaca gactacaaaa cagtgattca
    48601 acgtgtatta cgaatggatc tgacagaatt tgaaacacgt ccaacgggct tgtatctttt
    48661 tgactgtctt tctgttcgtg ggaatatctg ggtgttctgg cattcaaaac gaactgtaac
    48721 agaaaatgta cttgtgcaat tttcaggaca aggttgccgg gaatatgagg aagtcatgcg
    48781 tgaacaacaa acagattggc gaacatggct atattccatt tggaaaaatc aaggaaagtt
    48841 ggaagctggt tatacacgtg tgcaatgtag ccgattcgat attgcgttag atgaactttg
    48901 gggattggaa acggaagaac atttcgatct ctttgaatta ctagaaaaac aaaaagcagg
    48961 tttattagaa atggacttta agagattcca gaatattggc ggttgttttt tagatgatgg
    49021 ctattttcga agtgaaggat tatctttgta ttttggatcg cgaaagagtc ctctcttttt
    49081 taatttttat gagaaacgtt ttgaaattgc gaaccgagaa aaaatttcag aattagaagc
    49141 attaacgaaa tatggtattt ataatcgata tgagttacgg ttagccaatg agaaagcaac
    49201 acaagcagta gaagcattta ttttaggtga ttcaccgaaa cgtttaggag agattggcgt
    49261 tggtttaatt aatgcaaaac ttattgtttg ggatagactg gaaagtgatg cacggattgt
    49321 tgataaacga tgggcaaaat tatttcgttc gatggaagaa ttggatttta cagtaaagcc
    49381 agaaaaattc tcattagatc gttcagaacg ctggtttttg aaacaagtag ctccgacatt
    49441 aaagttgtta caagaagcag atcgtatttt aggaagagac tttgtacaag aagggattga
    49501 taatgccgaa ctaaatgacg agcaacaaaa ctatctagaa tggatgggaa cgtcaggagg
    49561 gaaaattgca tgaatgcata tacgacaaca gaatggctgc gcctgttgga tttaaaggct
    49621 gcaatcgaag cattaaatga aaagatggtt gatttgtctt attttcgttt tcgagttcct
    49681 tatattgaac aagcggtaaa agctggacgt tatcaggaaa aagagaactg gcaagaaatt
    49741 gcacgcttat tagaagttcg taagggatac gaacaagaac tcgaagagtt ggaatttagc
    49801 cgaaggaaag gaaggctaga attcattcgc ttttatcgat tttcattgcc aatacctgcg
    49861 attttagcgg ttaaaaaagg ctgcgataaa atgaagatat atgaaaactg tgtggcagca
    49921 cttagcagcg aaaaacctct tatggaagaa atttcattgg tgactgtcac ttgggaaatg
    49981 agtcgccagc caacagaaga acagacatat ctttctttag aagagattga gatagaatta
    50041 gaggaaattg gtcgctatgc cacttgttct acctattgtg gatcggtcat tagtattgct
    50101 ggtgtgattg tctaaatgaa aaaaattatg atttatgttg gtgcgtattg gtcacgtgat
    50161 ccaacagtat tagaaaatcc agaggcggta cactattgct tgcgccaatt attctatctg
    50221 tataaagaac gattagaatc gttgattcgt cagttaccat atactgacag acgtttagat
    50281 gaacttcttc taaggtatcc agcaatgtat aaacgacgaa aaaatagatt gttaccagaa
    50341 gagtatccca ttgaaaaaca tgaacttgaa gggcgatttg tggcttattt ctatgatgat
    50401 gttcgtatgc gcttagtaga acaacgaatg gaaatagaaa atgatcgcta ctattttatc
    50461 aattattgta agaagcgtaa gtatcaagta actgatgatt tttatgattg tattttacaa
    50521 gatggggaag tgattctatc caaaattgct ccaagttttc gtgaacttgt gccgattgat
    50581 tttttgaaaa aatgtcattt gcggattctt ccgtaaaaaa gagctataaa aggaaagaaa
    50641 agtagaagcc aaatcggttt ctgctttttt atttttttta ggaaggagaa gatggtatgt
    50701 cactggaatt tttaggagag ccaattgaaa aggaagagtt cgtttcgcat tatatggatt
    50761 tgtttattca ggtgataaaa aactttgtgc gattgatgaa ttttatccac gcgaacaaga
    50821 ctatctagcc gctgaacgaa taaaaatcag tttattatgg gaaaaattca cagatgaaaa
    50881 taaccgaccg ccagattatc gctatttatc agattgttta acgaataatg tgctttctaa
    50941 agaataccta tttcacaaac gtgagaaaaa tcaaatgtcg gttgaacatt tttgtgattg
    51001 ttatattgca ttattgcgta gtcaacagtt attaacagta gaacgatatg gtgcagagtt
    51061 tggttatgtc ttgcaagctg agcgtcatag agctacaaga tgctatgaaa aagaagatca
    51121 agtgattgat ggctatgaag aattatgtat tcgaaacaat cgctatttgc aacaacgttt
    51181 atatgaacaa ttgatgatgg atttttcaaa tctctataga gggtatgaat gttcgatgat
    51241 tcaagaaagg tagaagaaaa gggggaattt ttatgtggcg attattattt ttggtggtat
    51301 gtggtatggc attgttctat gtgtatcgtg tctatctcta tccacgaatg gaacgatgga
    51361 caagttggta tagagatcct ttaaaacaac gaaaaggatt gaagcggtat cgttatgaat
    51421 tacttgttga attttcggat gggcgacaag cacagtatta tttttttgca aactatccaa
    51481 aatacaacac cagtgaacta ttgattcaat tattcaaaaa taatccatat gttgggttag
    51541 aagaaaacgg acgggagttc ttttatcgtt cagataatat tagtgcggcg tctatgaaca
    51601 aaacacgaat tgcataaaaa attggaggaa taatcatgaa aaaaacaaca ttagcagtcg
    51661 taacaacact aggaatttca ttattttcgt ttcaattagg gagttcattg gtttatgcag
    51721 atgaaactgt agaaacacct aagtcagaaa ttgtagaaac attgccaggg gaaggattac
    51781 cagatgttga gacagagcta aatggaggaa caacggaaaa accagcagaa cctgaacaat
    51841 tgcagtcaga gaaacctgaa aaagagccag tgacaccaga accagagttt cctgaatcaa
    51901 ctttaccgac tgattcgatc gaagaagaag gtgtgcatag ttcaacaaca acggattcaa
    51961 gtatagtcac aactccggaa caatcaggaa caaccagttc ttctgaaaag aatactgatt
    52021 cgtcaagtac ggaacagcca acgatgtcgt ctaccagtga agaacaaaaa gaagaaccga
    52081 aacaacctgt tgaaaaatca gaagcaattc caaaagaaaa taaacctatt gttccagcaa
    52141 aagaagtcac agtatcggta accccaagcg gtgaaattac gacgaatact tctcaaggaa
    52201 tgagtgtacc gattgtcact agtaatgtag aggaattgac ccatattcca acaccaacca
    52261 ccccattaaa agtagcaggt gatcaaacaa ttgttggtgt aaaagatggt attccattaa
    52321 tccaagatag tgaagggaat ttggtaaagg atttgtcgat tcctgtaaag aaacttccaa
    52381 gtggcaatat tgaaatcaaa acagcagatg gaaaaacaaa agtcttacca aagactggtg
    52441 aagaaataca tgttgcactt tctgttctag gaggagtgtt gacaagtatt gctggatttg
    52501 ttggatataa aagaaagaga aaaggaatag aaaatgaggg taattgaatg gactattttt
    52561 cagaaaaaca agcttatcgt tgtcaatcgt acgtactagt aaaaacatac tagaaggagt
    52621 agcttatgaa aaaacgacaa ctacggcgga aagaaaaagt ttatacagag aaagtaccga
    52681 agcaaaagaa aatccattca aaaaaagcag tgaaatggat ttggtgtttg gttttatttc
    52741 tttgtttttc agggggcttg gcattttttc aatccatgaa aacgaaggtt caagtgtcgt
    52801 ttttgaaaga tgaaatccaa caattacaaa agaaagaagt acaaagtcgg tcagaattaa
    52861 cgtacacacc tgaaattgaa tcctttatga atcgttttgt tgctttgtat atgaatacat
    52921 tcgataatca tgaacaagaa caacaacgtc aagaaacatt aaaaaaagag ttttatgcac
    52981 aaaactttat tcaagaacca ggaagtgttt caggtgttcg aaaattaact gctgcttcgt
    53041 ttattggatt aaaagaaatt gaaaccattc caactgctag ttataaagta acttatgata
    53101 ttcgctcgat gaatccagag agtaagaaag aaacaagtgt gacaatcaca caagtactca
    53161 atcttccctt ttctatttca aacaagggct gtcgtattat tgcttatcct tattttacgg
    53221 cactaccaaa gaatacagaa aaacaacgaa tgattactta tgatgacaca ttatacgaaa
    53281 cggttgatgc gtcggaagcg aaagatgttg aaggatttgt ggaagatttc ttagataagt
    53341 atgcgaaaaa caatgcaaaa gatatgtcat acatgatgaa agaacctgaa ggactcaatc
    53401 aaacagctaa agttgatcaa gtagagatga aagtattgcg ttataaagaa acgaaaaaac
    53461 cttttattgt aaaagcaacg gtcgtctttc gagatggtga tacgtcactt ttacaaaaag
    53521 aacaaatgac gattgtcatt acgaaaaaaa caaatcagta ttatgttgaa aaattaacac
    53581 ataattggtt ggataggaaa ggagaagaac ggaaatgaca ctgaagggaa ttgtagattt
    53641 tatattaacg caaggtggct attttttaat aatggtggtt gtttatctgg gattgcgaaa
    53701 ttttatgaaa tcaaaagtag gaaatgcatt aatatctatc gcagcaggtg ccgcagttta
    53761 tttcttctta aatgatccaa cacgtgtatt tgatgcgttt ggtaaaatca ttgaaaaatt
    53821 atttatggat taggaggata gtgaagtgga ttgggaacct tatgattatt cgattgttta
    53881 tgcggaacct tatcgcgtac aacagattac aagcaattgg cgtcttccat ttccagttgc
    53941 attagtcaat gcagcaactt ttttgttggt cgtaatcttt gaatatttat ttttacgttc
    54001 atttattggt tgggtcattt ctttttttcc accagcagga gttgtttttt atataggact
    54061 cccctattta tgtgtgttag cactggcaaa actaaaacct gatggaaaaa aagtgcattt
    54121 ttatttatgg gattggtttt gttatatgat tcgtatgatg aatggtgatt gtgtgtatta
    54181 taactgggac aaggtatcaa acaatgcatt ggaagaatta ctttttgtga ataagtatgt
    54241 ttatttagag gattagaaaa agggacaatc aactggttgt tcctttttta ttgggaggtg
    54301 aaattcattg gtgcttgtaa aagaaccagt aaaagcattc aagaaaaatt gtttgttaaa
    54361 tggagaggat tgtatctggg cctactatca tgtttttcca cgaacaattt caaaaaacac
    54421 accaaaaaag acacaggaaa taaaagaaat gatggctcgt ttactgttgc ttttagcaga
    54481 ttatgaagat gtggagttgg tgatgtatcc acgaacaatg aatttacgga cgaagtttga
    54541 cacattagga aagggatttt ctcccgatag tcaagcaatt ggtgcgtatt atgcaaaaga
    54601 aacagtgaca ttgttggaac gagaaggtca agtctatcgt ccttcattta ttttaggaat
    54661 caaagtcaaa gaaaaagcaa cggtggagag ttttcatgat gtaataaatc taatctggtt
    54721 agatttagca ggaagtttag cacgcttatt tggattagaa gtagatgatt tggaaacttt
    54781 gttttctgaa agtgatcctt atgtaaaaga agtgacacaa ttactttata gcttttctat
    54841 tcgtccctta gtaaaaaaag agctgttgta tctcaatcgt ctgcaatata ttcgaggaat
    54901 ggctcacaaa gtagaagaac aaaataattg ggaagtactg aaagacaatc aaggaacgta
    54961 tgtacgtata ccgaaggaac ataaaggcct tcttcaatta gaagatgagt tagggagtag
    55021 ttatttagca ttgttgccta ttggggaaac acctgaaaat atgagaaatt gtgatctatt
    55081 tcaatttgct caggatcttt ctttcccagc agaattgcga atgaaaattc actatccacg
    55141 cttgaaagga cagggaggta ttggtttaaa actgaattgg ctatcggaac ggttcaaaac
    55201 agagcataag gaattggttc aaaatgatga agaacctagt gaacgcttat taactgttcg
    55261 aggattagta aaacatttaa agcaacgagt agataatggg caacctgtcg tcgattggat
    55321 cgcatgtttt attgtatacg gtcaaacggt tgaagaagtt cgtcaaaata gtgcaacggt
    55381 tattcaacaa cttcatacga ttatccatat ccaccgtgca aaaaatgatc aacgagaatt
    55441 gttctataaa tgtttattag ggcaaccatt gggacggcag ttacattgga agcaccgaac
    55501 aactgtagaa gcagttggcg aatggttgtt ttcagcagta tcagaattag gtatggaatc
    55561 cggctggtat attggtcggc aagatacatt aggggatggt ggttctcgag gagaaaaaac
    55621 accattagaa gaattaattt atgcgtcaaa tcgttttgtc tttttgaatc ttctagccat
    55681 tgcggaagga atcaaaggtg cgttgtttga tgcgcctcat gtagcagtaa ctggaaaaac
    55741 cggtaaaggg aagacctttt tagttggctt gctctttttg tatagttcgt ttatgaatgt
    55801 acaaagttta tttgtggatc ccaaaggaga aaagcgcaaa tggtttacga aactcattca
    55861 agacccgtat tatcagaaac attacccttt gtttgtagaa catttgcaaa aaatgagtta
    55921 tgtcacgtta gatgctacaa atccccgtaa ttatggtgta ttagatccaa ttgtttgttt
    55981 atcccgagta gatgcgaaac aagtagccca ggatatgatt gatgagttaa gtccgttagg
    56041 taccaatcac cttttaaaag gggcggtatt aaagggaatc caagaagttt tagttcaaaa
    56101 agaagccgga caacaagttg gcttgatgca tgtggtcgac tatttagaac aaatggaaca
    56161 aaaagaggtt cgagaatatg gtgagttttt acgcttgacg gtagaagatt cgattttacg
    56221 tttaggattt tcttatggag aaaacccggg attagacttt aatgccaaaa caacgatttt
    56281 agagatccaa gatttgaaat taccaaatga caatgtccga ccagaactat atacagatgc
    56341 ggatcgaaag tctttgtgtt tgatgattag tttaggtcgt ttttgtgaaa tgtttggaaa
    56401 acgagatagt agtaagaaaa cagcgattta ttttacagaa gcatgggtat ttaataattc
    56461 gaacgcagga cgtagtatta ttgcagcaat ggcacgtgtg gggcgttccc agatgaatca
    56521 attagtgtta gatacacaat ttattggtga cttaggttca gataaagaaa aagggaattt
    56581 tggtgtcgtc tttgcttttg atgaagacag tgagcgagaa aagattttga atcatttacg
    56641 tttggaagta aatgaagcga acttagctga aatgagccac atgattaaag gacagtgttg
    56701 gatgttagat ccctatggac gtgtaggaaa actcaatgta cacagtttgt ttgaagaaat
    56761 gaccgctgca ttacaaacaa cggaaaaaac aagtcactct caagtagaag aacaggatac
    56821 gttaatcatg caatagaaat gaggtgaaac aatggcttat ataaagcata aggaaaagaa
    56881 atggtgcgtt ttgttttttt taacgattgg attcggactg ctttttgttg gtggattggt
    56941 gtatgcggca gaaaagcagg tggatcaatc gatctatgag attgggaaat ttcatattga
    57001 taccttttct tcttatttat ctgatagtga attttcatta ggcaaaatgt tatttggggc
    57061 aaatggcaca gattttctaa aaatgatgac gaatatgttc tttagtttaa gtaaattgat
    57121 ttggcaaggc cttgattttg tcattgagaa gctctatgaa ggagctgcaa tgaacgagtt
    57181 aattcaccag tttttcactt tttcggatac tatttattca aaaatatacg atcctattgg
    57241 tgcggggatt gtcgtcttgt atgtgttata tctatttact cttcgtatat ttagagggaa
    57301 acattacgca aaaatggtgt ttattcgatt tctcttcgtt gtcatttttt caatggtttg
    57361 gtttggctat ggtagtaacg tacctagtaa aggagaagct tttaccaaag ggttaaatga
    57421 tttgtccgtg gaggtagaag gctttatttt ttctgctaca aatagtctag atgaattggc
    57481 gacaaaagat gtcaatggtg ttttagtgcc aacgacacaa aaggaagcca ttcaaaaagt
    57541 gcgccaactt tattataaag cggctgttgt tgatccgtat atattgttaa attatgggac
    57601 aacaaattta gaagaattgt atcaagcaga gattgaacca caagaatttc tagccaagga
    57661 agcgtcaagt gaagaattat ctgatattga gacaaaagtg accactgctg caggagaaga
    57721 tagagggaaa aagaaggctt atcgtgtcta tattcaacca actaaagctg tttataaagc
    57781 agtcgttggt tctatggtgc cattgcttaa tctaagtatt ggattaccac ttgtagtgat
    57841 tggcatgatt cgttttatct ttcaaatgtt ggtgttgtgt ttattacttg tgattccttt
    57901 ttcattactc gcttcttttg ttccagtatt tgattatatg ctcatgaata ccttaaagtc
    57961 ctttttgggc ttgatgtttc aaaaatcttt ttacagtgtg attattttgg tggcattttt
    58021 gatctataac atagtagacg atttaattcc aatgaatact gtttttggtt ttttaggaaa
    58081 tatgtttgtc aaagcactcc tatcaatttt actcattgta aaacggaaag atttattaaa
    58141 gaaactaggg ttaggagctg cagatcaaac tataaacaac acgaaaaaca tagcaagtca
    58201 ttctttgtct caaatgaaac aactgcctgg tcaactatca actgctggac aaaatttggc
    58261 aatcaaaggt gcaggattag cagggaatgt gtatcgagca acgaatccac tcgcttctgc
    58321 agcgatacat ggatttcaaa agtttcaaca aaaacgtaca ccacaagaat cggtaaaagg
    58381 gaggcaagtg gttaatccct ttgaactagg tgggcgttca aatcaagcct tgccttatag
    58441 tggtcgtcat gttcgttatc atggggtaga gcctgaaatg tcttctacca aatcgaaaac
    58501 agagtggaat tctggtcttt caaatggttt gattccaaat tcgtccatga attcagtaag
    58561 accaaaacaa caggtacaat cattggcaca attgagtaag caacaaggga ataatcaaag
    58621 aaaaccattg ttaaataaag gtatcgcttt tgttggtcaa tcgattccgt tgccttctgg
    58681 aaaagtaccc gtgccacaat taacagctgc tggttctctt tcacaacaga ttcgccaagt
    58741 gaaaaatcag gcgaaaaatg ggagttatcc agcaatgcag cagttattga accaatactc
    58801 tgttcctaat tcgtcggtag ccactctatc aggaaatcgt tctgtgcaac aaccggggca
    58861 acgttcgtct gaaagtaaac cgtcgatttc cgcaccaaaa tcgttacaac ctgcattttc
    58921 ttctttagat aagccaacag agcaatcgga aaaaatagaa aaggatccta aaacactgcc
    58981 gattttggac gcaaaaccag gaactgattt tactttacca aaaggacgaa cagtccaaaa
    59041 accattatcg aagaaaggat gaggaagaaa tgaagaaagg gtgtctaggt tgtcttcttt
    59101 tctttattct tccctttttt ctattgccat tctttttttc aggagaactt tctgagcatg
    59161 gaggagaagc tacaggtcta gctgtcgctt ttaatgggga atataccgaa ggattaccga
    59221 ttttttcaga gattaaagga cgtggtccaa tcacagatga acatgcgcaa gcagcagttg
    59281 gtgcagctgt aaagtatcag ttattaccga gtgtgattct ttctcaatta ggctatgaat
    59341 cagcttatgg acagtcacaa tctggaagaa acgatacgaa cttttttggg attacctggt
    59401 ttcctggttg tccctaccca caaggttctg cacgtggaat tggtggttct gaaggtggtt
    59461 tctatatgaa gtttccgaac ttaaaagctt gttatgacta ttatggcttt atggtggcga
    59521 gccaaagcaa ctttaatcaa tgtgtgggca ataaagatcc tggaagttgt ttattgattc
    59581 taggtcgtgg aggctatgcg gcagcaggta ttaccgaagg gagtccgtat tatcgaggag
    59641 caatgagtat cataacgtcc tataacttaa cggaatatga tacttttgcg atcaagcatt
    59701 ggaatagcct accaacaaaa aaaacttcgc ttattgcagg aaaaagtaaa ggcaatgcga
    59761 aggttttgga tcggatcatt ggacgatccg taaataatgg ggaatgttat ggtggtacgg
    59821 catggtatgt atctcaatta ggtggcccac agttaatggg ttctggacac atgtttgcga
    59881 tgttaatagg ggaagattat aactggacaa cctatggttg gcaagtaatc atgaacccaa
    59941 aaccaagtga tttacaagca ggagatgtgg tgaattggca agcaggtggt gcattgtctc
    60001 ctggaatcta tggtcacacc ggaattataa cagatgtttc atatggcgga caacatttct
    60061 ctagtgtgga acagaatgcc gagcaaggac ggattatggc tcggtatcaa cgcacgtaca
    60121 atcaaacaaa aattcgtagt ctggttcgta aggtgaaata agaaaggcag tgactagaaa
    60181 cgtgaaaaaa gggataattt tagtatttag ttggttatgt ttgataggtc ttactggttg
    60241 tcattggttt tcttctgaaa aacaaaaaac acaattgaga acgacagaag aaacaatcga
    60301 agcagtaaaa gaaacaagtg gaactcttca aagtactgaa agtaacagtc aaattggttc
    60361 attagaagac gagacagcgc aacaaatgca aatagatgaa atgacaaaaa atttcttaaa
    60421 agattttgct agaaaatgga gtaatttcac agatgtttat aaacgcaatc aagctgtgag
    60481 ggactatatg acagatcgtt gtattaaaga caatagtatt gatgtagacc cgcatgtaca
    60541 aatgaaaaca actgggaaac tttaccaggt gacacaagat atagagaatc cggatcaata
    60601 tttgttattt ggagaagaaa caatgaataa ggttactcaa tttgtattac ttcaattgaa
    60661 agtaggtcaa gaagctcaaa agattgatgc gatcaagatt tattatgtac ggagtgcgta
    60721 ttaaaataaa aaatgaacac tcatatttat tatacaccga agaaatagaa aaaaacagac
    60781 tgttttttta agaaaaacta tgtcattctt tacttgaaaa aagttgttat aggacagaaa
    60841 ggataaaaca aaaacggaaa aaatatgtct tatgaataac tataagaact attctatttt
    60901 ttaggagatg gatacgagat gaaaaaacta attggctata gtgtgatgtg tattggattt
    60961 gttggtgtgg gattgtttgt atcgactgaa tctgcttctg cggctgaatg gtataatcct
    61021 atctggtata atccgaacat tgaatgtcaa aaaggctatc cgtatggacc gacaaatctg
    61081 aaaaatggaa aatgtagagt aaattggaat ggcgttgtag atagtgtaat tactggttca
    61141 atggactctg ctctacatgg ctttacgggt cactagaagg aggaagaaaa tgtctgaaga
    61201 gaaaaaagaa atcgttgaat cattagtagc tttaaaagat tctctttcta agattgaata
    61261 tgttgatagg caagaaattc aaaaactaat tgatgatact attattgaaa tccaagatgc
    61321 gcgttgtgaa ggtataaaaa tttctgtagc tttatctaaa gtaatagaaa aaatgaaccg
    61381 ttcattagcg tttaatggat tgaagctaga tagacaaact agtctgatat gggatcattt
    61441 aaaagacttg tatgacaagt ctaaaagaag tgaacggact gctgtatcaa tcttaaaagg
    61501 cctttgggga atgaattcat aaacaagata tttaaaaagt aacttatttt ttatggagga
    61561 gaaattatga aaagaataat taaaatattt ggtgttttag gtgttttctt attaggttta
    61621 agtacttttg ttagtactgg aacaagtgtg tatgccacag aaaaagtgaa tacagttgat
    61681 ttagaaataa agaataaatt agtagatgaa ttaacttttt attttgatac agttggtttt
    61741 ttagacgaac atggtgtata ccatataaag gattttggtg ctattcgtga acgaatcagt
    61801 caagataacg aacaaggaag agcagcaaga gtcttttatg aacatattat tgttcctaga
    61861 atggagaaag ttgattggaa acgatatgct ggatgtgtag ccattaattc tcttcctgga
    61921 ggaggagtgg cttgggctat aggtacgcag ggagatttta ttgaagcatt aaaagctttt
    61981 aattttgaaa aagctgcgga tttattatta aaaattgcag aaaaacaatt aggaaaagct
    62041 gcagctaaag agttagctaa ggtaaatatt gtagcaggaa ttgcagcagc tgctgctagc
    62101 tgtgcattag agtaaaagtt tatgaaaagt ttagaacaag agcatatggc ttttaaacaa
    62161 gcaatgttta aagaaaatat ctatttaaac cataactata ttcgtgtttc taaggcatgt
    62221 tcaccagtat tgaatatgct tggaggtgga aatggattat atcatttact gtttgtcgat
    62281 gtttgttggt taattttttt accagatgaa ctagttatag tcaatgaaaa aataacaagt
    62341 aaaaatgaag tgtttaatta ttctttaaca agaattaatt acaaagagat taccaagttt
    62401 tcactagaaa aagttccttt ttggggagaa ttttgtttaa aaattaaatg taactggaaa
    62461 agaatgtatt tctatattga tggtgatgat gctcttacat tcggtaaaac tactttttct
    62521 agttttaatt ttcagtttct attaaaaaat aatttttatg gtttattgaa ataaggttgc
    62581 gaaggaagat gtagagttat ttgcactgtt gtgttggtat atctcttaat gctgtgtctt
    62641 tttggggaga ttaattagtg gagtgattat atgagtatag atgattgttt agaagaacaa
    62701 ataagattat ttttaaagtt tttaaaagtt aaagttcaaa ataactactt cacatgttat
    62761 agttatgcac accctgtttt aaatagtctt ccttttaatt ctttagtgca aggattgatt
    62821 acaaatattg ttttattagt ctgtacacca aatgaaatat ttgtaaaaaa gataggcagt
    62881 ggtatttctt cagtaagatt aaaagagaaa gaatatactc aaaagattat tcatattcct
    62941 aagcctgaaa ttaagcgttt tgagataaaa gactattctg ctttagggct gttctcaatt
    63001 ggttactggt gataaaaaat aagaatacta aaactatacg tagaatataa gtaatcggca
    63061 tcaatcctaa ttatgtgatt gaatgccgat ttttgttacg cgctattttt aattatctgt
    63121 aagaagaata attttatttt actcatattc gttttcactt tgaagaagta aattgcaatt
    63181 tcttataagt taagcagcta tgcaaaaggc tatttattct attgtgaaat ataagatgta
    63241 gttgaaacag gatatataga atcaaaatac gaatcttatt ttgatttttc tagttttttg
    63301 aaaaaagcac cctttgatcg ttgtattagt ggaaaagaga aaaaggagca tacttatcat
    63361 gtcacaaaac tacaactaaa tatctaaaca acaccaattt gatgcctatt gaaaaaaagt
    63421 attgcgaaat gaagccaagt ctattagaaa atgaaataat agaataaaag aaaatgggaa
    63481 accgctgaat gatgtaaatg aaggtaagta tccacgaact aattttgatg aacaagatat
    63541 ctatttttta tttgtattgg agatactagt ttaatatcaa aagttatcag cagtcataat
    63601 tagttatcca atgtaaaaag tacaaacaat agttg
//
LOCUS       DAFLWC010000004        60487 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.004, whole genome shotgun sequence.
ACCESSION   DAFLWC010000004 DAFLWC010000000
VERSION     DAFLWC010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 60487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60487
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.004"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..1420)
                     /locus_tag="L1V17_000240"
     CDS             complement(<1..1420)
                     /locus_tag="L1V17_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HBN1235034.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAG"
     gene            1672..2853
                     /locus_tag="L1V17_000241"
     CDS             1672..2853
                     /locus_tag="L1V17_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBN1235035.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            complement(2913..4541)
                     /gene="treC"
                     /locus_tag="L1V17_000242"
     CDS             complement(2913..4541)
                     /gene="treC"
                     /locus_tag="L1V17_000242"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBN1235036.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(4992..7703)
                     /locus_tag="L1V17_000243"
     CDS             complement(4992..7703)
                     /locus_tag="L1V17_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1235037.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            complement(7713..8414)
                     /locus_tag="L1V17_000244"
     CDS             complement(7713..8414)
                     /locus_tag="L1V17_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1235038.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            8600..9199
                     /locus_tag="L1V17_000245"
     CDS             8600..9199
                     /locus_tag="L1V17_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBN1235039.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            9280..10293
                     /locus_tag="L1V17_000246"
     CDS             9280..10293
                     /locus_tag="L1V17_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBN1235040.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            10401..11318
                     /gene="rbsK"
                     /locus_tag="L1V17_000247"
     CDS             10401..11318
                     /gene="rbsK"
                     /locus_tag="L1V17_000247"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBN1235041.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            11346..11741
                     /gene="rbsD"
                     /locus_tag="L1V17_000248"
     CDS             11346..11741
                     /gene="rbsD"
                     /locus_tag="L1V17_000248"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HBN1235042.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            11741..13114
                     /locus_tag="L1V17_000249"
     CDS             11741..13114
                     /locus_tag="L1V17_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1235043.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            13471..15615
                     /locus_tag="L1V17_000250"
     CDS             13471..15615
                     /locus_tag="L1V17_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBN1235044.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLRLDKSFWLDLPLKK"
     gene            complement(15667..16707)
                     /locus_tag="L1V17_000251"
     CDS             complement(15667..16707)
                     /locus_tag="L1V17_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBN1235045.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(16984..18786)
                     /locus_tag="L1V17_000252"
     CDS             complement(16984..18786)
                     /locus_tag="L1V17_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1235046.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            complement(18800..19552)
                     /locus_tag="L1V17_000253"
     CDS             complement(18800..19552)
                     /locus_tag="L1V17_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1235047.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            complement(19561..19923)
                     /locus_tag="L1V17_000254"
     CDS             complement(19561..19923)
                     /locus_tag="L1V17_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBN1235048.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            complement(20099..20971)
                     /locus_tag="L1V17_000255"
     CDS             complement(20099..20971)
                     /locus_tag="L1V17_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBN1235049.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            complement(21022..21510)
                     /locus_tag="L1V17_000256"
     CDS             complement(21022..21510)
                     /locus_tag="L1V17_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBN1235050.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            complement(21648..22439)
                     /locus_tag="L1V17_000257"
     CDS             complement(21648..22439)
                     /locus_tag="L1V17_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBN1235051.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            complement(22494..23102)
                     /locus_tag="L1V17_000258"
     CDS             complement(22494..23102)
                     /locus_tag="L1V17_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBN1235052.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            complement(23095..23412)
                     /locus_tag="L1V17_000259"
     CDS             complement(23095..23412)
                     /locus_tag="L1V17_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBN1235053.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            complement(23568..24296)
                     /locus_tag="L1V17_000260"
     CDS             complement(23568..24296)
                     /locus_tag="L1V17_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBN1235054.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            24455..25336
                     /locus_tag="L1V17_000261"
     CDS             24455..25336
                     /locus_tag="L1V17_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1235055.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            complement(25573..26616)
                     /locus_tag="L1V17_000262"
     CDS             complement(25573..26616)
                     /locus_tag="L1V17_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBN1235056.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(26619..27287)
                     /locus_tag="L1V17_000263"
     CDS             complement(26619..27287)
                     /locus_tag="L1V17_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1235057.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            27429..29765
                     /locus_tag="L1V17_000264"
     CDS             27429..29765
                     /locus_tag="L1V17_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1235058.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            complement(29880..30191)
                     /locus_tag="L1V17_000265"
     CDS             complement(29880..30191)
                     /locus_tag="L1V17_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235059.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            30372..31847
                     /locus_tag="L1V17_000266"
     CDS             30372..31847
                     /locus_tag="L1V17_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBN1235060.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            31894..32478
                     /locus_tag="L1V17_000267"
     CDS             31894..32478
                     /locus_tag="L1V17_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HBN1235061.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            32480..32863
                     /locus_tag="L1V17_000268"
     CDS             32480..32863
                     /locus_tag="L1V17_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HBN1235062.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIK"
     gene            complement(33180..33464)
                     /locus_tag="L1V17_000269"
     CDS             complement(33180..33464)
                     /locus_tag="L1V17_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HBN1235063.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(33816..34526)
                     /locus_tag="L1V17_000270"
     CDS             complement(33816..34526)
                     /locus_tag="L1V17_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HBN1235064.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(34523..35995)
                     /locus_tag="L1V17_000271"
     CDS             complement(34523..35995)
                     /locus_tag="L1V17_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBN1235065.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            36133..36606
                     /locus_tag="L1V17_000272"
     CDS             36133..36606
                     /locus_tag="L1V17_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBN1235066.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(36759..37310)
                     /locus_tag="L1V17_000273"
     CDS             complement(36759..37310)
                     /locus_tag="L1V17_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBN1235067.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            37415..37945
                     /locus_tag="L1V17_000274"
     CDS             37415..37945
                     /locus_tag="L1V17_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HBN1235068.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(38428..38871)
                     /locus_tag="L1V17_000275"
     CDS             complement(38428..38871)
                     /locus_tag="L1V17_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1235069.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(38887..40047)
                     /locus_tag="L1V17_000276"
     CDS             complement(38887..40047)
                     /locus_tag="L1V17_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBN1235070.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            40554..42254
                     /locus_tag="L1V17_000277"
     CDS             40554..42254
                     /locus_tag="L1V17_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235071.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(42356..43189)
                     /locus_tag="L1V17_000278"
     CDS             complement(42356..43189)
                     /locus_tag="L1V17_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBN1235072.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(43493..45658)
                     /locus_tag="L1V17_000279"
     CDS             complement(43493..45658)
                     /locus_tag="L1V17_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1235073.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            45918..48212
                     /locus_tag="L1V17_000280"
     CDS             45918..48212
                     /locus_tag="L1V17_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBN1235074.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            48205..48870
                     /gene="pgmB"
                     /locus_tag="L1V17_000281"
     CDS             48205..48870
                     /gene="pgmB"
                     /locus_tag="L1V17_000281"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBN1235075.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            48863..49870
                     /locus_tag="L1V17_000282"
     CDS             48863..49870
                     /locus_tag="L1V17_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBN1235076.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            49892..50911
                     /locus_tag="L1V17_000283"
     CDS             49892..50911
                     /locus_tag="L1V17_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1235077.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(51192..52559)
                     /gene="nhaC"
                     /locus_tag="L1V17_000284"
     CDS             complement(51192..52559)
                     /gene="nhaC"
                     /locus_tag="L1V17_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBN1235078.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(52668..54089)
                     /locus_tag="L1V17_000285"
     CDS             complement(52668..54089)
                     /locus_tag="L1V17_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1235079.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(54332..56209)
                     /gene="tdc"
                     /locus_tag="L1V17_000286"
     CDS             complement(54332..56209)
                     /gene="tdc"
                     /locus_tag="L1V17_000286"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBN1235080.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(56500..57756)
                     /locus_tag="L1V17_000287"
     CDS             complement(56500..57756)
                     /locus_tag="L1V17_000287"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBN1235081.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(57868..58073)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            58336..59637
                     /locus_tag="L1V17_000288"
     CDS             58336..59637
                     /locus_tag="L1V17_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBN1235082.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(59706..60305)
                     /locus_tag="L1V17_000289"
     CDS             complement(59706..60305)
                     /locus_tag="L1V17_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1235083.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
BASE COUNT        18278 a        12361 c        10834 g        19014 t
ORIGIN      
        1 ttcctgcata taaatgaaaa tgttcggagt cagccggtgc aatcgtgtga tcactgaatt
       61 gaatatatct aaaagcgcca ctttccttat cttctgcttc gaatagatac cttacgccac
      121 ggtttcctgc ctcgtaggtc aagatttctt tccctacata acgataattt gaacgtttcg
      181 ttgttccatt cttaaacgta aatgccatct ctttctcact gatcttgatt gaagcaatat
      241 ctgtttgata gcccttcgta taatattctt tatattcttg tgctgtctta tcctgattca
      301 atttttcttt atattcaaaa acaggatcaa aagtcccatc ttctacatac gtatctactg
      361 tttgccaagt tcctgcccaa tctgaaagag agcgatcttg tacatcctcg tcttcaaaat
      421 aaccgttgta gacgctcttt tcttttttgg gggtcaaagt atcttctagc gggttttctg
      481 tctctgtcgt ttttttcaac gcttcgaggt ttgcttccat gatagaaaga tagttttctc
      541 cattttctat ttgttcattc gtcaatcctt ccaaaggatt caatacttct aaagatacac
      601 ctgcttcgtt tgctaacgtt ctggcaatac tatctttggc gttttcttca aaataaatat
      661 agttgattcc atgttcttta acaaagtgtt tcagttcagc aattctcgcc gcagacggtt
      721 cttcactaga agaaagacca gcaatcgata cttgattcaa tccatattct aacgctagat
      781 agttgaatgc agcatgttgc gtgacaaaag atctttgttt tgcttgctta aaggtttctt
      841 gataaagctg atggagtgct tgaagtttct cggtataggc tgctgcattt tttgtccata
      901 cttcctgttt ttctgggtaa gcttcaatca gctgatcacg tatgtttgct acctgcttga
      961 ttgctaaact tggagctagc catacatgtg ggtctagctc atgtgtatgg ccttcttccc
     1021 cgtgttcatg gtcatgatca tgtccttctt cacttcccgg aagtaaaagc ataccttctg
     1081 tcgcttttat cgtatggaca ttgccttctt gtaatgtttt ttggattgcg gggacccatg
     1141 tttccatgtt ttcatcatta taaacaaaga tatctgtatc ttggatcttt gccatgtctt
     1201 tagcagaagg ttcataatcg tgggaatcag tccctgctgg aatcaataac tctacttctc
     1261 cttcatcccc gacgattgct tttgtaaaat catacatggg ataaaaggtc gtcatcacgc
     1321 tcaatttttc tttactgtcc tcggctttcc cacttgcccc gcaagcagtt aacatacctg
     1381 ctaaaaccag catggccaat atacctatca atcgtttcat ttatgacact cctcttctca
     1441 tcttctttca tttgaatgtt ccgattcgct tttcgcaaac cgtaatagtt acgttttagc
     1501 aacaggattt aatttatcat atggttaaaa gaactgtcaa gcgttttctt attttaattg
     1561 atgagaaagt ttatatgaat gattgacgat atttttgcaa tcaacctcta tcattttcct
     1621 tttatacccg cttttgtcta taatgaagtt atagataaag gaggaaaaag agtgaaaaaa
     1681 gaaacagata caacgaatcg tttgatccgc tttttaggag gaaaaacctc ttactatgtt
     1741 ttaggaatag ttatcttact tgcgctgatc atttattttt tccatcagat ctcgtttata
     1801 ttcaagcctg tcggaatcat tatcgctact atcttgcccc cattattgtt tgcactgatc
     1861 ttgtattatc ttttggaacc agtcatcaaa cgtttgagca agcacctttc gaggaacttg
     1921 tcagtcatta tcgtttatgt gattatttta tttttattgg ggcttggaag catatggctt
     1981 attccttttc ttgaagaaca ggcaaagaca ttgatcagta gtttgccaga tttgtttcaa
     2041 gattttcaag agagtctccg acaatttttg gagaaaacac cttttgccga ttcatttaat
     2101 caatttttcg cttctattga cgacgtgacg tctgatatag ctggatttat tggaaattat
     2161 tgggaaagtg gcgcacaacg gatcagcaac attttttcaa ctgttacagc tatttttatt
     2221 actttattta ctggtccaat tgtcgctttt ttccttttga gagatcctca aaaattttat
     2281 cagtcagttt tagcgattgt cccaccagca tttcgtacag attttaaaaa tttgacaaag
     2341 attgctaatc aacaattggg ttcatttcta aaggggcaaa tcattgcttc atttatcctt
     2401 ggagcagtct actgggtttg tttcttactg atcggattag aatttgctag tgttttagct
     2461 atttctgctg ggttgttatg tatcattcca tatattgggc cgtttatcgc cttctttcca
     2521 ggtttgatca ttgcattcca agactctact tttatggctg tcaaatttgt cattgtctgg
     2581 tttgccgtac aacttctcca cggtgacttg gtgattcctc gagtaatggg tgatcgttta
     2641 cagatccatc cgattacgat cttaatcgtt ttacttgtca tgggtgatct aatgggaatt
     2701 gtgggcgtta tttttggtat tcctatctat acgttagtca aattactcgt tacttttatt
     2761 ttccgtaaat tcaaacaacg ctacaataaa ttttatggcg ataaaggaga gtatgaaaac
     2821 tcttcatttt ctgaagaaga ttattttaaa taaaacacaa aacgtcgatc ttacgagaat
     2881 agctcgtagg aacgacgttt tgtgtttttg ttttaatttt tcagcaaagc aattgcctgg
     2941 tatggtttta gctccagact ttgatgaaga acagtatcgg aataattatc gataagaata
     3001 ttggcttctg tgaatccttc tgggatggcg atccttgtat ctttatcata gaaatttgtt
     3061 aatacaagca gctgctgtcc ttcaaattgg cgaagaaagc cataaacttc cggatgattt
     3121 gcttcataag catgataatc tccttgtgca acgattggat atgtttttct cagccgaatc
     3181 aatttcttgt aataggacaa aatagaatct tcagaagata gttctttttc tacattaatc
     3241 tcttctagct tgcctccaac ttttaaccaa ggtttccctg tagtaaatcc tgcttgttct
     3301 gtgtctgacc attgcatggg tgttcgagag ttatcgcgag attttgcttt gatccgacga
     3361 aacgcttctt tttctgtgaa tccttgttca aggagtaact tataagcatt caaactttct
     3421 acgtcaatat agtcggaaat cgatgaatag tctgggtcga tcatgccgat ttcttctccc
     3481 atataaatat agggcgtccc acggttcaaa tggatcatgg ttgctagcat ctctgctcct
     3541 tgttttcgat actgatcgat agctacaaat cgattgagcg cacgtggctg atcatgatta
     3601 ttaaaaaata gagcattcca gccgttaccc tcactcatct tttctcccca tgtatgaaat
     3661 agtcgcttta attctgcaaa atcaaatgga ggagtagacc atttattccc attttcataa
     3721 tcgactttca aatgatggaa attaaagacc attgataatt cttctctact aggttctgta
     3781 tacaagatac aattttcgat cgtcgtagag ctcatttcac cgactgtgat gatagtggaa
     3841 tccgtcccaa acgttgcttg gttcaattct tttagatacg tatgggtgat tggtttgtcc
     3901 gtatattcag gtttgccatc attttcttta ttatttttca attgttcgtc tttaccgata
     3961 acattgataa catcgaaacg gaatcctttt accccttttt ccatccaaaa acgaacaact
     4021 ttgaatagtt cctctcttac tgcttggttc cgccagttca agtcagcttg tgtccgatca
     4081 tataagtgca aataatattt ccccgtatct ccaaatggcg accaagcact tccaccaaat
     4141 tttgataccc aatccgttgg ctcttctctt aaaatgaaga agtcctgata atgctggtcc
     4201 cctgctagtg cttttttgaa ccattcatgt tctgtcgaaa cgtgattcag caccatatcg
     4261 agcatgattt ctatccggta tttctttgct tcggctatta gctgttcgaa ttcctccatc
     4321 gtaccaaaga taggatcgat ggctgtgtaa tcagagatat cataaccgtt gtctttttga
     4381 gggcttggat aaatagggtt tagccaaatc atgtcgatgc ctagatcatt cagatacggg
     4441 agtttttctt tgattccttt taaatctcca attccatcac cattactgtc tttgtaagat
     4501 ttgggataga tttggtaaat gactttgtct ttaaatgtca tggatattta cctccattca
     4561 actgatttat tacctaccac aacttatata tacaagttat catttattat tataactgaa
     4621 ccgaaagcgt ttgtaaaatt tatctttata cattctaaga ggtctgttgc ccaataaaaa
     4681 acaagagatc agacatgtat ttgtctatcc tcttgtttaa aatagcaaaa tattcttgtt
     4741 tcttctataa atggtgttca aaagctttta tctacggcaa tcagtcttct caaatgtaaa
     4801 acatgaggag ctaattttat ttgagtattc tttttgctcg atgcaggacg gcttttttac
     4861 aacctctgat tcatggtgtt caatcagctg tccttcggta ttagctcaaa aaacggcaaa
     4921 atatgaaaaa ctattttgcc gtttgtttct ctaatactca ggtcaaaccg ctgatttcac
     4981 aacctctgtt tttattcatt cgatttcaac gcatcaatca tatcgatatg ctttaatttg
     5041 aaatgggtaa caatcatcac aataaccgta aatacgatag ttaatcctgc tgataagaca
     5101 taagcccacc atgtgatcac taatggaaag atgacattct ccatagacgc ttgttgcaag
     5161 atgaagtcag tcaatatata tcctacacca aatcctccga tgattcctaa aagagtaaag
     5221 atgatatttt ctcgaacaat gtacatcgtg acttctttat caaaaaatcc aaggactttt
     5281 attgtagata attcgcgtac acgctcggaa atattgatat tagttagatt atacaagacg
     5341 ataaaagcca gcagtcctga taatacgaca aagattaaga caaccgagtc taagttcgcc
     5401 attgattctt cttgcgtttc gatttgtttg gacatgaaag acgtatttgt cacagcgtct
     5461 gtggcaagca gtttctcgga aagcatttct tcttcttttg ttgtcatctt atctgtacgc
     5521 agcaaaaatg cattatccat catcgattga tcagtaactg aagcataata ttcaggggac
     5581 atataaataa agctacctag atagtttttc acgatttctt ttacttcgac tttccattct
     5641 ttttgatctt catcataaag cgaaatatga tctcctgtag ataagtcaaa tagttctgct
     5701 actttttgcg taatagcgat tcctgtttta ggcaaggagc gtgggttctc ttcaagatca
     5761 gttaaatgga taaaacgatc caaatcagct gttttacttg gtacgatcac tgtcagactt
     5821 tgcgaagcat gtcctttttt tctcaattct acggtttgag tatgaatagc taggatctca
     5881 tttacttttt cttgcttctg cagcatatcc gctgcttttt gacgactatc ttccgtggat
     5941 gaatccaatg taacgattgc ttgatagtca atgatcggtc caaattgttt ggctgaaaca
     6001 gaacttagag aatctttcaa tcccacgcct gcaaccatca gcccggcaca tccagcaatt
     6061 ccgataatcg ccataagcat tcttgactta tatcggaaga gatttcggta actgattttt
     6121 tgattaaagc taaggcgtga ccacagcgga gtgatgtatt caagaaaaat gcgtttccct
     6181 ggcttcggtg ctttcggttg aagcaatgca gcaggccgtt ctcttaaatc tttgaataaa
     6241 acgatcattg cagcgccaaa tgcggcaatg aagaatgcgg cagctgcttg taaaatcggc
     6301 ggccagtcat aaaaaataag cgcactccca atatcatacc gctcgttaga cagctcaaaa
     6361 atgatccttg gcaaaagatt cgttcctaat atcgttccta aaacaatacc tatccctgag
     6421 gctagacttg catagattgc atattttttt gcgatttcaa ctttcgtata acctaacgcc
     6481 tttaatgtcc cgatttccct gcggttttct tctaccatac gtgtcattgt cgtaaaggtg
     6541 atcaatgcgg caataaagaa aaagaaaaca ggaaaaacat tggcaatcgc agcgatacga
     6601 tcagacagat caccaaattc ttgaaaaccg acattttctg aacgttcatt gtataggtat
     6661 gatggtttag ttaaattttc aattttttct gcatttcgat tcaattcttc ctctgcagag
     6721 gccagttcac gttctttctc aactaattgc ctttcttgtt cagcaagttg agcttcttgt
     6781 tgagataatg tttgaacagc gattgttcgt tgcgcttcag gaagctgctg gatagttgct
     6841 gactgttgcg ctaactgttt tttagcatct tctaaccgtg ttcttgcttg cgttgtttgt
     6901 gctttgccat ccgctatttt ttgctgtgcc ggttctaatt cttcgttggc cgattttttc
     6961 agctcttcta agcgttcttc gggtcgatct tgtaaatact tttctgcctt ttcttgattt
     7021 tgctccattt tatctttgta agctttgctg tacgtattca aattctttac gtttgtaaaa
     7081 tcaagatata agacagaata aatatctgtt ttaaaaacgg attcaggtaa atagacaaaa
     7141 taatcgacgc taccatttcc gacgttcgcg tatcctctct ccaaattgtt gatgaacaat
     7201 ggagaacgga caaagcccgt gatggtatac tctttttctt tcaattcatc tgaatcaatc
     7261 tgataaatat caccgatttt atacccttca tcttccgctt tttcatccaa tacaagctgg
     7321 tttggttttt ccgggagttt tccatcagtt aattgtagct tgttctgctt gttatttttg
     7381 ttataagaaa atatttgaat cacttcgttt ttgccagtat tggaataata gatctgtttt
     7441 cctgtttcta cttttgcatc tgggatcttt tctgcttgag caatatcttt ttgtgtcaag
     7501 ccaccagtag aaacgatttg caaatcagaa agtcctgctg taccaacata gtgatccatc
     7561 gttttttgca tgacaggtcc agcagttttg acacctacaa ataaaagtgt tcctagcatg
     7621 acaataagga tgattgcaat gaatcgtcct ttagattgcc gaatttcgcg aaaacctgct
     7681 ttaagatatg ttcttgtttt cataaaatcc ccctaccata caatctcatc aatggatgaa
     7741 ggatgatcat ttaattcaac agaccttact ttagcatcat taatgtgaat gactctatca
     7801 gcgatgggcg ctaaagcaga attatgtgta atgatcaaaa cggtattgcc gtgttgtctg
     7861 ctagcgtttt gcaataattt caatacttgc ttgcccgttt caaaatccag cgcgcctgtc
     7921 ggttcatcac ataaaagaag tttgggattt ttagctagtg cacgagcaat tgaaaccctc
     7981 tgctgttcgc ctcctgataa ttgggacgga aagttattca atcgatgagc taggcccact
     8041 tgcctcaata cctctacagg atcaagcgca tcaggagaaa cttccgttgc caattccaca
     8101 ttttcttttg ctgttagatt aggaacgaga ttgtagaatt ggaaaacgaa ccctacatct
     8161 gttcgtcggt aagcagtaag ctgtttatct gaaaattgcg caatatctgt gtcatcaata
     8221 atgatctgac cttcatcagg tgtatccatc ccacctaaaa tattaagaat cgttgacttt
     8281 cctgctccac ttggaccaag tataatcact aattcgcctt tttcaattga aaaagaaata
     8341 tcgtcatttg ctgtaatggt cgtttctccc attttgtatc gtttgtattc attttttact
     8401 tcgacatact tcactctgat tcctccattt tcacgatatt tctcgctata tctatgcatc
     8461 gaatgcgttt tctcacactt atttatttta ccactgaatt tctctagact aaagaaagga
     8521 atcctttaat ttagttgaca aataaacgat ttatgattta cttacataaa aaacattgtt
     8581 atttgaaaga aggaacatca tgaatgattt aaaggaaaat atgatttttg atttatcaaa
     8641 aactgctttt gtcgcgatcg acatgcaaaa agagatcgta aataacggta cactctctcc
     8701 acacactgca gcatctattc tgacaaacaa tgatttgtta gtaagaacat tgaaacgtac
     8761 cgctgccttg aaagttttag tgaacgtaga catctccact ttcccttatt tgagtcaaca
     8821 aactgatatg ggtggaatga ctgcttctgt acctccagaa ttcactgatt tacttttgaa
     8881 ggattctttg aaagatacag ataatatgtt gactatcaca aaatacaatc caagtgcttt
     8941 ttttggtact tctcttgatc ttcaacttcg ccggcgtgga atcgaaacta tcattttaag
     9001 cggtgtagcg acaacaaacg gtgtatatgc tactgcatta gatgcctttc aacacgggta
     9061 ccatatcgtg cttgctgaag atgcttgcag tgatcgtgac aaagaatccc atcaattgtt
     9121 cataaaaaag atatttccga aaactgcacg agtacgctca acgaaacaaa taatcgaagc
     9181 tatccaacaa agcaaataag tactggcaca cgtgattttc atttacttct ttttgatttc
     9241 atgggaaaat aaccacagga tttagatagg agtatgaaca tggtgaaaaa aaagatcaca
     9301 atcaaagaag tcgctaaact ttccggcgtt tcaatcacaa ctgtctcctt gatattaaat
     9361 ggaaatacgg agaaattcag tccgaaaact gttcagaaag ttttagctgc caaagaagaa
     9421 ttaggctatc agcctgacta ttttgctaga caaatgatta ccaaggaaac gaaaacaatt
     9481 ggtgtactcg ttcctgatat cacgaatcca ttcttcagta cactgatgcg aggaattgag
     9541 gatatcttgt ataagcagaa tttcgtcacg atattatgta atgctgattc tgatcatcaa
     9601 aaagaaatcg aatatctagc cgagctcaca cgtcgaggtg tggatggatt cattatcgcg
     9661 acttctgctg tctctacaga tgcaatcaac gaaaatttga aaaaacaagg ccggcccttc
     9721 attgttttgg atcagaaaaa atctgaagga tttagtgatg ccgtacgaac agacgatttt
     9781 cgcggtggtt acctagcggg catgcacttg cttagtctag gacatcaaac gatcgccctt
     9841 gtctatcctg aaaatccacc ggaaaatgtc cacgctcgga ttgaggggtt taaatctgct
     9901 cttgatgttt accaaatccc tcacgaccaa ctgatcctct tacctacaca gttctcaaaa
     9961 caaggtggct accagatcac agcagaactt cttgattctg ctgcaactgg tgtgtttgct
    10021 ttaaatgatg aattagcttt tggattatat cgcggattag aggaagctgg aaaaagcatc
    10081 cctgaagact acagcattat tggctatgat aatatagata tgtgcgagta tatcaagccg
    10141 aaactgacaa cgatcgcaca accaatcttc gaattgggac aaacatctgc caagttattg
    10201 ttagatcgga tccaattccc agaaaaagaa tgggaagaaa aaagattacc tgtacgatta
    10261 gaaaaaagat tttcaactgc acccttgaaa tagctttcaa ggtgtgctat atttttatcg
    10321 aactattaaa acgttttact aaaacgtttt aaaaaataat tttcccatca aaataaatga
    10381 gatagttgga ggtttgtaaa atgaacacgg ttacagtaat tggaagtatt aatatggaca
    10441 ctacccttcg tttaaccaac atgcccaagc caggcgaaac gatgcatgcg catgagattt
    10501 ttcacgctgg cggaggtaaa ggtgccaacc aagcagtggc agccaaacgt tcaggcgcac
    10561 ggacatcttt tattggaggc gttggggctg acagcgaagg acaacagtta ttagatctac
    10621 tgacaaaaga aaacatcgat acatctggga tagctgaaat ccaaggcgcc acaaccggac
    10681 aagcaatgat tatggtagac gcagcaggag aaaatagtat cttgatccat gcaggggcaa
    10741 ataatgcttt ccatgaacaa gaagtcctaa aaaacaagca actgattaca aacagtgact
    10801 ttattattgc tcagtttgaa agtagcttag atgcgacgat cctagctttt tctattgcaa
    10861 aagacgcagg aaaaacaacg atcctgaatc ctgcaccagc tcgtgaaacg attcctactg
    10921 aactacttga aaagacagat atcattatac caaatgaaac agaaacagaa atcattacag
    10981 gaatcagagt gacagatcat aacagtttgg tcgcagcagc cgaaaaactc catgaattag
    11041 gtattggaac agtaatcatt acactaggca gtgccggcgc tttctatcat acagaaaaag
    11101 aacacggtat cgtccctgct tttaaagtgg atgccgttga cacaacagcc gcaggtgata
    11161 catttattgg cgcattaagc agcacacttc agccagacct tagtaacttg aaagaagcga
    11221 tcctttatgg aaatctagcc tcttctgttg ctgtgcagtc ttatggtgcg caaccttcta
    11281 tcccttaccg cgaagcttta gaacaatcag cagtctaaaa ttaacaatga gaggaagaaa
    11341 caaacatgaa aaaaggaaaa gtaatcaatt cagatatttc acgagtaatc gcacaaatgg
    11401 ggcactttga taaattaagt atcggggatg caggcatgcc tgtccccttt ggtactgaaa
    11461 aaatagattt ggctgtctca aacggtcttc caagtttttt atctgtttta gaaaacgttt
    11521 tagaagaact tgaggtacaa tcgattgaat tggcggaaga aataaagaca atgaacccgg
    11581 aaatattgga aaaaatcaaa ttattgttac cagatacacc gattagcttt atcccacatg
    11641 aagaaatgaa aaaagagttg aataactgtc atgcatttat tcgtacaggc gaaatgacac
    11701 cttacgccaa tattatatta gtgagtggag tggtcttcta atggaaacga caatgaatcc
    11761 tgaacagatg gtactgtccg agcagattca tatgctgatt gaacagttgg gaggaaaaga
    11821 caatattgat tctgtccttc catgtgcgac tcggcttcgt atcaaattga aaaaacagcc
    11881 agtagccaat gcagaaaaat taaaacagca aatcccttcc attaagtatt tcattttact
    11941 cgatagatat gcagaaataa tcatggatca gggattggct cctgcttaca aggaattgac
    12001 gcgtcaaatc gatcattcag ctccgaaaga aaagctaaat ccgatcgaaa aactatttgg
    12061 tttgatatcg gaaatcttta cgccgatcat tccgctgttt gccggttctg gtatattaaa
    12121 aggtctggtt gttttagcga ctacgattgg ctggcttagt gaaacaagcg gaacttatca
    12181 tattttgtct gctgcgtcga atgccgtctt ttattttctg ccaatctttc ttgctttttc
    12241 tgctgccaaa acgtttaaag tgaatggata tattgcggct gtcattgctg cagcactgat
    12301 tgaaccgaat ctgacctctt tactttcaga cagtggcaaa gcagctactg attttctggg
    12361 gattcctgta gtactgatgc agtatacgtc tactgtcatg ccggcgattt taggtatttt
    12421 cttttattct tttgttgaaa aattcctcaa aaaatatatt cgcgaaaata tgcaattagt
    12481 atttgtacct ttactttcat tagttatcac ggttcctttg acgttaatgg tattcgggcc
    12541 tgcgggtgtt taccttggcg aaggtttagc tgccgcaatt acttggatga tggatattaa
    12601 cggaccgatc agtggcgcaa tcatcgctgg tggttggaat attttggtaa tatttggtat
    12661 ccaatgggct gtaaaccctg tcatgatcag taatatctct gcttatgggt tcgaccgaat
    12721 cgttccgttg acaggagcag ccaattttgg aatggctggt gcagctttag gtgtatttct
    12781 gcgaagtaaa cgttcaaaaa cccgttcgat ctccggttct gcttttgctt cgattttact
    12841 tgcgggagtg accgaaccaa ctgtttacgg aattgcgatc ccattgaaaa aaccatttgt
    12901 tgctgcttgc attggtgcag ctgctggtgg agctgtaatg ggatttgccc aagtgaaagc
    12961 gatcgctttt gtatttggta gtctgaccac attgcctgca ttcatttccg gtactttttt
    13021 ctggtactta gcaggactgg ctgttagtct agtcgtagca atgatcacta ctctcgttag
    13081 cgggtttgat gaagacctaa tgtcttatga atagttaatg aaaaagactg aagtatgaga
    13141 tgtttatcac atatttcagt ctttttcttt ttaggatcat tatttttata aatttttgtg
    13201 atactttcca aactttggta taatttacat atgcataacc atttttatcc ccacttgttt
    13261 atccccaaac aaaggtggtc tatgcaataa aatgaacgtc aaagaaaaac gaatgaatgc
    13321 tcgttgctta tttacaaatt gttttattta gaatacacag acagatttat gaaaagaaaa
    13381 agcttttcga cacgattatc tgttccaaaa aatgtctaat gaatgctgaa taagacagaa
    13441 aatcaatgaa aggaaaagga ctagtttatt atgaaaaata aaaaaacgat acgtttgcta
    13501 gctgctactt ggctgattgc tccgtctgtt ttgtcgacca ataccgtatt tgccgtagat
    13561 aatcaaatag ctgatcaaac agtcacaaca gatacgacta catccagctc agctactagt
    13621 gaaacaacgg attcttttac agaagaccca actggaacaa ctaactcaac aacaggatcg
    13681 accgagccaa ctgaaattga tccggctgat ccatcagaaa atgaaaagcc agccgagaca
    13741 tattccctta caattgctcc ttctttgatt ggtaagatcc aactgactgc ttcgacagcg
    13801 gattcccctg aacagcaacc tttggatatt acggaaagtg gaacggtaga aggtttatta
    13861 gcggaaacga aggtaactta cactattacg ccagctgaag gtgaacaaat tgcttcagtc
    13921 gctgttaatg gtgccaaaga agtaaattat gatgcaaaga cctttacagt aggtacgaac
    13981 aatttatcta ttactgcaga atttaaagct ggaccggata cttcaacaga gaaaccaact
    14041 gatcctagtg aagaagtccc tagtacacca gatccggaaa cgccaaacaa accagatgtg
    14101 ggtaataaca acaataataa tggttcaaat aattcaaaca ataataacaa taattcgaac
    14161 agcgggaatt cttcgaatca aacaaaccca tctggatcga ataacaatgg aaatactcag
    14221 agagaaccaa accatccaaa caatggttca tcgaatggcg gaacgaacaa tgcttcatct
    14281 cgtccaaata cagcaaatca aagcggtata gagaatccat cttctgcttc ttctgatttt
    14341 gttgtaaaat caccaattga tgctgtattg cctacaaata caacgaatgt ccaacaagca
    14401 atcgttcgag aagcattcaa gcatcttgga aaaccatatg tatggggagc aaaaggtcca
    14461 aatacttttg actgttctgg tttgacttat tacgtatata tgaaagcaac cggtcattat
    14521 atcggtggct ggacaggcga acagcaatat gcaggtacgc agattccagt aagtcaggcc
    14581 caacctggcg acctcgtctt ctggggacct tcttccggtg ttactcacca tgtaggtatc
    14641 tatattggga acggacaatt tatccatgcg cctcaaccag gagataaagt tcgagtaact
    14701 tctatttcag atttcacgcc tgattttgct gtccgagtaa acttagcagg tttacctgct
    14761 gcttcaggtt cgctgacagg cggctcatct attttagatg gattagatgg ctcgttccat
    14821 ttcagtcaaa accaaacaac tgatcagttc ttgaaaaaga ttgcagatga tgcacaggaa
    14881 atcgggcaaa aagaaggaat ctacgcatca gtcatgatgg ctcaagctat ccttgaaagt
    14941 ggatctggaa acagcttatt atcaagcgaa ccaaatcata acctttttgg tatcaaagga
    15001 tcatataaag gaagcagcgt gaccttcaat acacttgaac aagatagttc cggacaaagc
    15061 taccaaatcc gcgcacaatt ccgtaaatat ccttcttaca aggaaagttt ggaagactat
    15121 gccgacttga tcaaaaatgg actgactggc aatcctgatt tctacaaacc aacttggaag
    15181 tcggaaacaa aagactacaa agaagcaacc aaatatttgg aaggacgtta tgctacagat
    15241 cgccaatatt cacaaaaatt gaacgcgatc atcgaagcgt acgacctgac aaaatatgat
    15301 gaaccgaaaa aagaagcagc aacaactgaa gaagcaaacg ctgaaatcct caatatgtct
    15361 aagcgattcg atgtgccaat caaatggaca acagatggcg tgccaatcac aggattagaa
    15421 ttttcaacga taaaacgcgt caacaacgct tcttccatct tccgtgtcgc ttcaatctgg
    15481 gatttgtgga acaattttac ggcaagacag ataccagaaa caactactcg tacagttaaa
    15541 gctgcaactg ttcctgtact aaccttgtta aggttagaca aatcattctg gcttgatctg
    15601 cctttaaaga aatagaataa attaaaaagg ggatgtgaca ctgtcacact ccctttttaa
    15661 tttattctat ttctttatat ttattttgta ttccgttaca aactcgcgta cttggttagg
    15721 ttccagagtg acatctccaa aactttcaag tcgctccgct cctggcagtt cttgagtctc
    15781 aaatgtgata ccgccatgat ttactaattt attcccgcgc atttccggtc catcttctcc
    15841 aaaatttgct gtaaaaatca cgattcctga agcatctgtt tttacttgga tcgatacttt
    15901 ttcatctggg cttgtcaatt ccgcagcatt tagtaaacca gattgttttt tcaacaaaaa
    15961 tggatgatcg atgccgccca ctatcattga ttggcgaaaa tcactggcaa agacctcacc
    16021 taatttttta ggacgttgga agtcaaatgc tgtgccactt actgaaacta cttctcctgt
    16081 aggcgttgta tctttattga gcgtagcaaa taatcggcta ttcaaccaaa gtatatgttc
    16141 gtcgattgac tgtgctggat caccggttaa attgaaatag acatgatttg taggattgaa
    16201 tactgttttg cggtcactga tcccttggac cgtcactcgc catgtatcat cgttcgtcag
    16261 cgtataccgt acttctacat ctaaagttcc aggaaatccg ttttccatat ctgggctagt
    16321 ctgatagaaa atgaccgatg cttcgttttc accattgatg actgtataat gccactgctt
    16381 ggcttcaaag ctaggtgcac caccatgtaa acaatgacca gtgtccgggt ctgtttttac
    16441 ttcgaacgtt tcatcatcta atttgaatgt gccattcgta atccgtccag ccatacgtcc
    16501 gattgaagca ccgatataag ggtctttttc tagatattct tttgcttcat caaaacctaa
    16561 gatcaactct cgtttttcat tatcgattat tgtttgaaaa tgaacaaccc gtgccccaag
    16621 atcactgaca gacaaagatg tcccattttg attcgtgatc gtaatcaagt gatagttttc
    16681 gccaaaattt tgttcattga tttccatgtt ccttgcaccc tcttttcttt catttgcact
    16741 gattccagta tacatggaaa ccgttttctt aacagcttat tccgtgagta acgagaaaaa
    16801 atttactata ttctaataaa agaccgtgaa aaaaaggttg tgacaaaaat attgtcacaa
    16861 cctctttttc cgaacaaacg gtgttcaaaa gcttgcatct gcggtaataa gcccaaccaa
    16921 acgaaaaata tgaggagcta tttttgcttg gctgttctta ttacttgatg caggacagct
    16981 ttttcacaat ctctttttca atacgattcc agtatataac catgtcgtca gtacatagta
    17041 gatgaaatac aatacgaaga atatcgtaaa cggaacccaa atatctttgt atggattttg
    17101 catgaataga ccaaacattt gtaatccgaa taagacatgg actacaccta agattcctgg
    17161 tgctaagaat aacacgccta cttctctacg gatcgattgt ttaagcaacc cgcgtcgtgt
    17221 tcctatcttt tcaagcattt cataacgagc aatgtcactc ttgcttcctg acaagatctt
    17281 gaacatcaaa cagctagcaa gcatggtcaa gaaagctaaa cctaggaaga atcccataaa
    17341 ttcaaaacca gagaatagac cattatacac ttcatacatt tcatatttct ggttgctgta
    17401 ctctactttt tgcaaagatg gattgttcat tttattttga gcaacaagtg tttcgattgg
    17461 tttcaggttt gcttggaagt cttttacctg aactagctgt aaagtggatt gtggcaagtt
    17521 cagttgatca aattctgatt gactgactac cttgatttct ttttcttgct gttccggcaa
    17581 ttcatagctt cgaagttcct cttgtacagt cagttcattc atttttttag caggaacttt
    17641 ttctttcgtg atcttcggcg gtgttccatc ttcatgtttt atcatgatca atggttgagc
    17701 cgcaaattca cttgcattat agtaaatcgt tcccgcatct tctttttgag tataagaagc
    17761 agaaagtgtt ggtgaaagtt ctttgatttt ttgctgatct tctgcccgag gattattcat
    17821 cactagatca tatccagaat tgttttctgt caagtctgca atttcatttt taaaacctaa
    17881 tcctaccgtc aaagcgccca gtgccaaggc aaacagcata gcgaccattg agagcatttg
    17941 tgtatattca cgaatacgaa agtttaactg tgacaatgtg aaattgttca attttttcaa
    18001 tgaaatctgt tctgatttct ttagtaatga taaaaagaaa atgatcacag aatggaaaat
    18061 gaaataagtt cctaatacga tcgtaactaa ggctacccct ataccaaaga cttgataggt
    18121 ccccacgtgt ttcatcatat agtaaccgca gcctagaaaa gcaattccca gtactacttc
    18181 aaggaaaaac aagaatttat gctgcttgat tcttgttggt gtctgatccg cacgaatcaa
    18241 tgctaaaatc ggttttttga caatcgaaaa agcattgaca acagcagcta ataaaaacaa
    18301 aacagcaaaa aacaaaacag tgatcaacaa cccgtgaata ctaaaaggtg taaaatgcga
    18361 aatattgaga tctaactgat ccactaataa tcggtggacg atacttgtca atcctacacc
    18421 gacagctgaa cccactaaag tagctgcgat ccctactaag aatgtttcag aaaaaatcat
    18481 ctgtgcgatt tttctgcctt ttgctcccag catcataaac attgcatagt ctttttgccg
    18541 catcgtcatc aaaaaggaat ttgcatataa aatataaacg aatgtgatga tccctagtaa
    18601 aacagaaccg aatcggaaaa tgataactgt agccgcaacg atcgtattac ttttcaaaaa
    18661 agcttcgttg cttgccattg attcaaacat gtaaaaaata gcagatgcca taactaatcc
    18721 tgagaataac accaagtagt ctcttaaacg gctcttgatc ccagtaagtg ataatttcca
    18781 aagcatagtc aatctccccc tactgttcca agtttccaag aatagatagt atttctcgat
    18841 agaaggaatc acggctttga tctccacgtt tcacttcttg atggataccg ccatccttga
    18901 tgaataaaat acgttggcaa taacttgcag aaaacggatc atgcgtcaca agaagaatcg
    18961 atacatgatc ttttgtattc aattcgtcca tcgtatctaa aagatcccgg gcacttttgg
    19021 aatccagcgc acctgtaggc tcatccccta atagaatcgt tggttgtgtg atcaatgcac
    19081 gtgcggcggc gacccgttgt ttttgtccac cggaaatctc agaaggatag ctttccaaaa
    19141 tatgagagat ggataaacgt tctgcaattt tttggacacg ttgcttgatt tcttttggtc
    19201 tgacgccttg taaagaaaga ggaacagcga tattttcttg tgctgtcaag ctttctaata
    19261 aattgaaatc ttggaaaata aagccaatct cattcgcacg aaaatctgct agttgatttc
    19321 cttttaatgt ggtcacatct ttttgattga ttcggatatg cccatctgtt ggtttatcta
    19381 atgtggataa aatattcaaa agtgtcgact taccagaacc agaagcgccc atgatcccaa
    19441 taaattcgcc tttttctaca tcgaagctga tgccgcttaa tgcttgcgtc tttttctcat
    19501 tgttttttcc gtatactttt gttacattct gtacttcgac tattttgttc atttctttcc
    19561 ctacccttta attagttttt ccagtgctgt tttcggcacg tctttttttt cgacttcttc
    19621 atacgaagtg acacctttat ttttgttcca ggtgattttt aaatatgctc ctttacgaag
    19681 cggtcgagtc aattgtccct tgaagtccag ttctttttcc ttaccctctt tcgtatagcc
    19741 aggcaggata tatctatagt tgactgtttc ttgtccagag tctgattttg aaactgtttt
    19801 tgtaccatct gtcgtaattt gtacatagta ttcttctcca cccataacta cgtaatctgc
    19861 gattttcacc cctgcaagta ccacaacgat gaaaacaagt agaccgatca gaagtttttt
    19921 cactttttcc ccttctctct tactttatat actgattata gaaaaaagcg aacaattctg
    19981 ccttcgaatc aactatcatt cttctttcaa ttttgtcatt ttctttaaaa caactaaaaa
    20041 aagagttcaa gacaataatc cgtcctaaac tccttcttcc tatcttacaa aaagtatgtc
    20101 acttacggtc tttcatgtcg cctgtattga taacaggttg cgttcctttg tctgtaatga
    20161 ttgagacaag taaattattg atcaattgga ctttccgatc atcggtgaaa ttgatttctt
    20221 gtccatcttc gatttgctct aaggccattt gagtgattgt gacagctcct tcaacaatgg
    20281 tttgtcgagc agacaaaatg gcttttgctt gttgacgttg gagcatggca ctagcgattt
    20341 ctgttgcata ggctaaatgg ttcaagcgtg tttcgattac ttcgacacct gctactgcta
    20401 aacgctcttg cagctctttt tgcaactcgt cagacactgc cgtcgtgttt cctcgaagcg
    20461 tcaaatcatt ctcattgaat gtatcatacg ggtattggct agcgatatgc cgaatggctg
    20521 tctcactttg gatttctaca aaatcttgat aatacgctac atcgaataat gcctttgctg
    20581 tatcaacgac tttaaagact actactgctg agatttcgat ggggtttcca tccaaatcat
    20641 tgacttttaa aacagaacta ttgaaattcc gaactttcaa cgaaacagtc attttttgtg
    20701 ccaaaggtat cgtaaggaaa aagccatttt ctcgaatcgt acctaaatat tgtccaaaaa
    20761 acaaaattac ttttgcttga ttaggactga ctacagttgc cgaacttaac aacaataacg
    20821 tgatcaacca aagaaaaata cttaaaaaaa gtgcccaaac tttcgcttgc cacataccta
    20881 aatagaagaa aaacaatcca actaaagcta atacgaccaa tccgacaatc cctgcataac
    20941 cattgatata aaatgctctt ttttctctca tgctacttcc tgcgctcctt tatccttcaa
    21001 taaatatcta atgttacttt tttaattttt ttttcgaata cgcgccatta caccttctag
    21061 ttctaactct ttgtcttcag tgatgtacca accgcttgcc tgtgtccctc cggctgcctg
    21121 cggtaaataa tccaattttg ttcgaaccca gtgcttttct tctgtaaaat agtcttctac
    21181 caagacctct agatccatcc ctgctgaaag aggcaaatct tcccgaacag atttaaagat
    21241 aaatcgttcc ttcttcccat catacttcaa tattcctgta tcgataatcg gtaaagaata
    21301 ataatccagc tctttcttca ccgtcaataa atgtttgaaa acttcatggt acacttgctc
    21361 taattggcga ccttctgaat tgttcgggta attaaccatc actttttctt tgtctggatc
    21421 atagaaggtt tggcttagtt gagtgatata agtatgtaat ctttccattt ctgtttttaa
    21481 cttttctctt tgaccttctt ctaccttcat atactctttc accctgtttt ctttttagat
    21541 attttctttc ttattttact atagttatgt gcgttaagcg atgaaaaaca gcaaagattg
    21601 gaaggatctt tgctgttttt tcttaaaata tccagttgag tacaggatca atctgtttca
    21661 ttgtcctctt gatccgtcgt aatattgatc gatgtgtctt tagcagtgat ctttagcttt
    21721 ttctgtcctt gttctaacaa agtatttgtt attggctggt agtctttttc aatataagat
    21781 tcaccagacg tttggatagt atagccactg ttttccatct catgcaaaga taaattgcca
    21841 ccgtttagga tgacttttcc ttctttgctg atcaaactgt cttctagatg gaagttgctg
    21901 ttttcacctg tgacgatcaa gttatccaca ttggcctcat ctaatcgaag tgagcctaat
    21961 tcatctttcg cagttattgt tcctcctgta aattcattga acgataccca gccatcatgt
    22021 gtcttagtat tcactttttt gattgatact tcgttgatat caattgcact attattccct
    22081 tcgattgtca attcagataa ttcatgatct gcagggacaa caatagtgat ttgtgcactt
    22141 gtgtcttcta aactaatgat tgcacctgtt gattttttga ctgcattcac agtcaacacg
    22201 ccatttttct cctttatttc tggcttttct gtcttatcat aagtcgtttt tatctcaaaa
    22261 tccaatccgc gtatgaccga aactgtttga ttttctgcat ggatgacgat tttgtttgca
    22321 tccttgattt tttttgtctc agtaaccata tcgatcaacc gaggaccatt atcccaagtc
    22381 agactctttt gagcgcctaa tgtataagtt gcacctgcta ggaggccacc agtaagcatc
    22441 agaccaatac cggtaatcaa aaaatgtttc aatctcaatt tatgtgtcct ccttcaaacg
    22501 cccgctgaat gcagatctct ttttgtaata aaacgtcgtc ccatccattt aacaaagttc
    22561 atcatgacat aaaaaagccc ttttgttcct ttcagcaaca gtggcgaaat aaatactgcg
    22621 cttcctgtgg cgaacagacc gacaccgata aagaataatc cactcagaat cgattgtcca
    22681 aacacactga ttcctgagat gatcatgaat aggccaacac ctaagatact gatacataaa
    22741 acatagatac taaaaatgag cgctagtaaa gcaaccaata gtcccccaat aaccaatata
    22801 aaccccagtg ctagtggaat gaggacagga gaagcaaata aaccgataat gattaaccaa
    22861 atcaggcgaa tttgtctttt tggatttttc actaactcgt tttctgcttg ttcttcttct
    22921 gaaaagtaac tgatttttaa ttttaaggca aactgctttg gtgtaccata ttcatcaatg
    22981 atctgatcta atgtttttcc agaatctaaa aaatattcct cataatactg gatcaaatca
    23041 aaacgatcgt cttcaggaat ttcttgaaga tgatccacaa cttcattcaa atattcattc
    23101 atttgtgctc tcctccaata accggtctaa agaatctcga aaaacaatcc attcatcaat
    23161 aatttcttct aaatgacgac ttcccattgg tgtcaacgag taatatcgac ggtttctgcc
    23221 ttcaaaaggt tcatcatagg tctcaagata tccttctttt ttcaatcttc tcaaaaccgg
    23281 atatagtgta gattcactga cagagagact ttcttgtacg atttttgtta aggcataccc
    23341 atacatatct tccttgctta atgctgctag cacagtacca tcaagaagaa cagttggaat
    23401 ctggatgtgc attacgtcac cttctattct caagtgtaat attttatttc aatctatatt
    23461 atacaacata taatatagtt tcaaaatcag tttgtcaaat acaaaaaaac tgactaaaag
    23521 atttgatcct ttttagtcag caaaaaatgg cttctctttg atttttatta taacagtggc
    23581 ataatccaat ttgtccacat ccagctcagt ggcatgataa cgatcattgc aggtatcatg
    23641 tcagctactg ggaacatttt cacgttgatc attctaaaac cggtagcgac catcaagaat
    23701 ccgccgcaag ctttaaaatc taagatcatg tctggtgtag tcaatggata aataaatttt
    23761 gccaataaga acaaaatata aaaaataatg aattggggaa ttgctatcac agaaacgaca
    23821 taccctaaat tacacgcaaa aatagctgct gtgaaaaaat caaggacaga tttagaaatc
    23881 aaaatcgtac tgtctcctgt catcccagaa tctaaacttc catagatccc cgtaccactt
    23941 gcacaaaata gaacaatgac cgtcactaat gtgctgataa attcatcgtg ggtcatacca
    24001 agcttttcac tagggaagat tttagaaata ggtacttgca tcagcgcagc ccccttattt
    24061 atcccattac ctaaatgaac aatcaaacca atcgctgttc ctatcactaa agcaaaaata
    24121 acagccggca tatttttcat cggcgcaatg gaatagattc ccatccccat cgaacacaca
    24181 ccaaaaacca tcgtcagctg tgctttaaaa tgttcactta atttatttcc tactaatccg
    24241 ccaattagtc cgccaaacaa aacggaacct acattgatca aaactccagt tggcatcaaa
    24301 aaactcctct ctttttctac gaagcgaaaa aaatcagaaa aatttctgta attattgctt
    24361 tcgctgcaag aaagattgta acagacagag aagattacac caattcattt tttgtgttaa
    24421 agtattcttt attggaataa gtaggaggaa tatgatggat atccataaat tcgaagtttt
    24481 tcttgattta gccgaaacaa tgaatttcac caaaactgct gatcgacaat tcaccaccca
    24541 aggaaatatt tctaaacaga ttctttcgtt agaaacagaa ttagacgtca aattattcga
    24601 acgcgcccat agaaaaatcg aattgaccga agctggaagc ttattgctcc catatgtaaa
    24661 aaatgtcgta gaacaatacc atgctatgca agaagtgctt gaaacctata cgaaagacaa
    24721 caatctttca ttaaatatct taacgatacc gacaatgatc aattataaag gtttttccaa
    24781 aatcaccgag tttttgaaac gccatcctga atttacagtc cagttgaaag aagtggaaag
    24841 tgtcgaatta acttacaatg acgccaatga acatagtgac acgatccact ttgctagaag
    24901 tttccaggcc ccaccaagtt cgattgagtg gttgcctact gaaacagacg attttgtagc
    24961 agttctacct aaaaatcatc ctttagctag taaaaagaaa ttggatctaa gcgaactgaa
    25021 aaaggagaac tttttgctcc ttggccccac tacgaacttg tatcaacctg tactagatct
    25081 gtgtcgcgaa gctggatttg aaccaaaaat ctcttataaa ggagcaagaa tcgacttgat
    25141 catcaatatg attgcaaatg acatggggat tgctattgtt atggaaaaaa cagtcaagaa
    25201 tctattaaaa gaaaatactg tgattctccc tatttctcca acaacagaga gttatcttgc
    25261 atttactcgt aaagtcggtg agcattcttt ggcttcagat acattttggg agtatttaaa
    25321 tcaagaagaa aactaagccc tacattttct gtccatctat ccacccaaaa aaagagagcg
    25381 acgcatgact ttcgctctct ttcttgcatc atgtccttgt ttcaatgaca cctctaacat
    25441 ttctcgtagt tcaataagaa agcagcgatt tttatgccaa aagaaccgta agaacatttc
    25501 cctaatcaca aaaaaacgac taaaaacccc taaaaacctt caatagaatt tttaggggtt
    25561 ttattctttt tcctattgtt tacttaaccg tatcattgct gtcgttccta ctccttcgat
    25621 actgctataa tcaatacgtc catcatgcag ttctagaatt tttttaacca gtgaaagtcc
    25681 tagcccattc ccagaaattt gacgacttgt atctccttga taaaattttt caaacattcg
    25741 atctctggtc tcttcattca ttcctacacc tgaatcggtc acttccagta caatctctgt
    25801 ggctgtctca aatagtttga tatgaatctg tccattgatt tgattgtact ttatggcgtt
    25861 atccatgata ttcagccaca cttggtacaa aaactcttca ttgcctgtgt aatttactgc
    25921 agcaagttcg atatccaatt ctagctgttc tttctcccat ttaggctgaa aaaaaacgat
    25981 tacttctctg atttgttcat ctaatcgata ctctttcttt tccagttgga tacgctggtt
    26041 ttccagtttg ttcaatttta agatgttctc tgttaattgt gaaagctgcg tgatactttc
    26101 gataatccga tataaaaata tttggcgttc ttcgtcagag agatttgggg cttgtaacaa
    26161 ttgaacatat ccttggattg ttgctagtgg tgttttgaat tcatgggata cactggacac
    26221 aaagtcattc ctcagtgtct cgatactatt gagttcttgg accataacgt tgaaatcttt
    26281 atacagttgc tgtacttctg ctactttctg ctgttcatcc attcgaatcg aaaaatctcc
    26341 cgttgctacc agactcatat ttgtccctag cgcactgatt ggatgcagga tacgccgccc
    26401 aacaaaaatc gatattcctg tacccacgac catactgaac cccgcaaaga cgaataacgg
    26461 gtataacgtt ggttttccag ccgattcagc aggcgagata gaatgtcgag acaataagaa
    26521 aataaaaccg agaaaacaca gcagtgtcac taagatcgaa atgaagacaa tactagcaaa
    26581 atagatccat aattgtgaaa atagcttttt tttcatcttt aaataaccgc cttatagcct
    26641 agtccccgta ctgtgatgat ttgaaaatct tccgtctttt caaaacgggt ccttaaacgt
    26701 ttgatatgta catcgatcgt tcgttcttct gtattcgtat ctaatcccca aatatcatcc
    26761 atcaactgtt ggcgagtgaa gatcttgttg ggataagaca gtaatttata cagaagcaga
    26821 aattcttttt gaggcagaat caacgaatgc tgatcttgta acactgtata agcatctagc
    26881 tctaattttg tttgtccgat tatcaagcta ctgctgtaat tgatctttga acgtcgaagc
    26941 aatgcttcca cacgtaggat catctcattg acatcgatgg gttttgtcat ataatcatct
    27001 gctcctaatt tgaacccgcg tttcttatcc tcaaaatcgg cctttgccgt aatcattaga
    27061 acaggtgtgt caaatctggt gctacgtaat gagtctagca agtcatagcc atccattttc
    27121 ggcatcatga tatctgtaat gattaattct atacgtgtcg cttctagttt tttcagcgca
    27181 tcctctccat tcaatgcggt gatgactgaa aagcccgctc gttccaacac agaacggtaa
    27241 agcaactgta attgcggatc atcttctact actaaaatac gattcattga tctccctctg
    27301 ttttttgaaa aatttctaga ttttttcttg tagttcatct tcagttaaca tttatttcgt
    27361 atactacgat cattgttctg atatacttat tagtataccg aatatttcaa tacgggagaa
    27421 gggtgattat gcttcaatta aaagatataa aaaaatatta taaagtcggc gaaaccacca
    27481 ccaaagcatt ggatggtgtg tctgtcgctt tcagacaaaa agaattcgta gcgattttag
    27541 gtcctagtgg ttctggtaaa acgactatgc tgaatgtgat tggtggacta gataattatg
    27601 attccggtga tatggtaatc aacggaaagt ctactaaaga ctttaaggac agtgactggg
    27661 atgcctaccg aaacaactct atcggtttca tttttcaaag ttacaacttg attggtcatc
    27721 taggcattat tgaaaacgtt gaacttggga tgacattaag tggtgtttct aaagacgaaa
    27781 aacgaaaacg ggcagaagat gcattgcacc gagtcggctt gacaaatcat atgcataaaa
    27841 agccaaatca gttatctggt ggacaaatgc agcgagtggc catcgctcga gcactagcca
    27901 atgacccaga tatccttttg tgcgatgaac caaccggagc gttagataca gaaacaagta
    27961 tccagatcat ggaattgatc caagagttat cgaaagaaaa attagtgatc atggtcacac
    28021 ataatcctga actggcccat caatacgcag atcgaatcat tgaattttct gatggtaaga
    28081 tcttaacaga ttcccatcct cacatcgaac gaccaaaaga tgatcaattt aacttacgca
    28141 gaacaaagat gagtttttgg acagcgttaa agctttcctt caacaatatc cgaacaaaaa
    28201 aaggacgtac tttcttgacc tcctttgctt ccagtattgg gatcatcgga atcgcgatcg
    28261 ttctgtccct ttcttctgga ttccaaaaac aaatcgataa cacgcaagct gaaacgatgg
    28321 cgaaatttcc gattactatt tctaaggtaa cgactaacca gactcgtgac gatgccggat
    28381 tgggtgcaag caaagcggat tatccagaca gcaaaacgat tactgcaaaa gtcagcgaag
    28441 aagataaagc acagcacacg aataagattg atcaaacata cgtcgattac gtaacagaca
    28501 tcgatcctaa cttaagtaat aatatcggat ttacccgtac tacaggaatc aatcttttac
    28561 gtgatgtaaa tggcaaagta cagcctgtca gcttctcgaa tcaaaatcct gatacggaat
    28621 ctctttcttt atctagtacg atgtcagcaa tgacaggtgt gggagtgtca agtttcccta
    28681 cacagcttga cactagcaaa gaaaactttt taaaagacaa ttattcttta cttgccggaa
    28741 gttatccagc ctcagcaaca gatgtcgtgc tgatcgtaga cggcaataat aatactaata
    28801 tcaacgcatt gaagaatctt ggatttgatg tgaaagaaga cgaaaaactt gattttgatg
    28861 atatcgttgg tacaacattc aaattagtaa acaacaatac ttactataca aaacttccaa
    28921 ctgggaattt tatccctaat acagattatg atgcgatgta tcagaatgct tctgatgaat
    28981 tgaagatctc ggggatccta cgcgtgaaat cttcttctac aatgaatctc ttatctccag
    29041 gaatcgctta tagcgatcaa ttaacgactc aaatcgtcaa cgaaaacaaa gaatcagaaa
    29101 tcgtcaaagc tcaaagagac agtggtgtaa atgtcttaac tactgaaaaa gttgacgaaa
    29161 atgccaaaca aacattgctt agttatttag gtggagacag cttgccttca agtatcatga
    29221 tttatccgaa caattttgaa gacaaagaaa agatcttgga ttatctagat gattacaata
    29281 aaggcaaatc agatgaagat aaaatcattt atactgattt agctggaacg atgactgaac
    29341 tgactggcgg attgatggat gctatcactt atgtccttat tgcttttgca gggatctctt
    29401 tagtaacaag tatgatcatg atcagtatca ttacttatac atctgtgatt gaacggacaa
    29461 aagaaatcgg tgtactaaaa gctttaggtg cacgtaaaaa agacatcact cgcgtatttg
    29521 acgcagaaac gtgtatttta ggtatttctt ctgggatatt aggtgtgttt attgcatggc
    29581 tagctacgtt ccctatcaat agcatcttat acaacatgac ggatctaaaa aatgttgctc
    29641 aactaaatcc tgtccatgcg attattctag tgatcgtctc tactatattg acgatgcttg
    29701 gcggtcatct tcctgcacga atggcagcga aaaaagacgc cgctatcgct ttgcgtgcag
    29761 aataaggttg tgacaaccac atttagattt gagtcataag agcgctgaaa tagtagaaaa
    29821 cagcaagaaa cgaggaagta atatgttcct tgtttcgcgc tgtttttttt aattattttt
    29881 tataattctg gtatactttt ctttcctttg taccacaact cttctggcgt atacctgtct
    29941 tttccattta tgaatactgt tccatctgct tcaatcgtta cttcagtccc aatccacata
    30001 ttacgagaaa gtgcgagaag attttttctt tttcctcttc ctttttttcc aaattgcaag
    30061 gcatcggtta tctcttctgt ccaatgagat ttcacgtatt ttacttctcc gttttcaaat
    30121 gtaactttca aaatattcgc tatattttcc acttttactg ctttaggaaa tgactcctcc
    30181 atttttttca ctttccttcc tccaacacta agtatgcgct ttcttttagt gataagtata
    30241 tcatagttta ttctattatc aaaaaaacgc atccattcca ttgtagaata ctttaccgaa
    30301 caagttgaat tgttttcctc tttttcacct tttactatag ataggtaaag acaactaagg
    30361 aggaatctct catgacagat caaccgtatg atttaagaaa agtcatcgaa gaactaaaaa
    30421 cacttccagg tcaatatcac gaaacagata ttgaaatcga tcctgaagca gaattatctg
    30481 gtgtttaccg ttatatcggt gctggcggta cagtaaaacg tccgactcaa gaaggaccag
    30541 ctatgacttt caacaatatc aaaggtttcc ccggcacacg tgtgaacatc ggaacaatgg
    30601 ctagtcgtaa acgtgtaggt gaaattttgc accatgatta tcgaacactt ggtcgtttct
    30661 tgaaagacgc tgtagaaaat ccaatcaaac ctgtgaaagt agacaaagca gacgctccag
    30721 cacaagaagt cgttcatcta gctaccgatg cagacttcga tattcgcaac attttgcctg
    30781 cacctacaaa tactcctgaa gatgctggtc catacatcac aatgggtgta gtcttaggat
    30841 cagatccaga aaaaacaatg agcgatgtaa cgatccatcg tatggttcta gaagataaag
    30901 atacgatcgg tatgtacatc atgcctggcg gacgccacat tggtcacttc caaaaacaat
    30961 tcgaagcctt gaataaacca atgcctatca ctatcaatat tggtttagat ccagcaattg
    31021 ccattggcac gactttcgaa ccacctacca ctccacttgg ctacaatgaa ctatggtgtg
    31081 caggagcttt gcgtaacgaa cctattcaaa tcgttgatgg tatagcagtc gatgaagtgg
    31141 gtattgctcg tgctgaattc atcattgaag cagaaatcat gccaaatgaa acaatgcaag
    31201 aagatatcaa cacgaactca ggaaaagcaa tgccagaatt tcctggctat actggggatg
    31261 ctaatccagc tgtacaagta gtgaaagtca aagcagttac tcaccgaaaa gacaatccaa
    31321 tcatgcaaac aacgattggt cccagtgaag aacacgtatc tatggccggt attcctacag
    31381 aagcaagtat tcttgccttg gtcgataaag ctattccagg aaaagtagta aatgtctaca
    31441 atcctcctgc aggtggtggt aaattgatga ccatcatgca aatccgtaaa gaaaacgaag
    31501 cggatgaagg tattcagcgt caagcagcta ttcttgcttt atcagccttc aaagaattga
    31561 agacagtcat tttagtcgat gaagatgttg atattttcga catgaacgat gtagtttgga
    31621 ctttcaacac tcgtttccaa ggagataaag atatcatcgt gatcccagga atgaggaacc
    31681 atccattgga cccatcagaa ttaccagaat ataatcctgg ctctattcgt ttccgtggga
    31741 taagtgcaaa aactatcttt gacggtacag ttcctttcga tatgaaagaa cattttgtac
    31801 gtgcaaaatt ccaagaagta gaagattggg aaaaatattt gaaataatga atgatctgca
    31861 actgttttga catcataaaa aggagtgcgg aaaatggaac aattggcaca acggaagaaa
    31921 aaaatcgtga ttggtgtaag tggcgcttca ggcaccattt atgccatcaa cctagtgaag
    31981 aaactaaaag aatatccgat gatagaaaca cacggaatca tcagtccatg ggcaaaacag
    32041 aacttaaagc tggaatccga cttatcacta actgaattcg aaagcctgtt tgattaccat
    32101 tattcaaaca aagatttagg tgctgctgtc gccagcggat catttttgac cgatggaatg
    32161 atcatcgtac cggcaagtat gaaaacagtc gcaggtatct ctgttggttt aggcgacaac
    32221 ctgattgcac gtgctgctga tgtaacaatg aaggagcaac gaaagttagt cattgttcct
    32281 cgtgaaacgc cattaaatgc cattcacttg gaaaacttga ctaaattagc acgactaggt
    32341 gtgcaaatca taccaccaat tcctgctttt tataatcagc ctcaaacgat ccaagatctt
    32401 gttaatcacc atacaatgaa acttttggat caatttgaaa ttgtaaatga gcattcaaaa
    32461 cgttggcagg gtgattaata tggaaaaaga aacgatagtt gaagtaacca aactaggttt
    32521 cacgatccaa gctgctgtta aagtaatcgg taaagactta ttgatcactt taacaggcgg
    32581 agatacacca catatcggaa cagtcactac attttctcgt gatacagaga tgcaaactgt
    32641 acgtttccct agccacgatg gtcggttcca taaagacgat gtcttagccg aaaaaatagc
    32701 tgtgatcatc aaaactgccg ttccgggaag ttgtacgatc acttccggta tccatgttga
    32761 ccatatctcc aatgcacaaa tcaacgcctc ttttccgatg tcagaagagt taggttacaa
    32821 gattttagat tggttggaaa aaatagattt ccatatcaaa taaccagttt attataaaga
    32881 tggtgaaaaa ccattatgaa agaagaggtt gtgaaatcag cgttatgacc tgagtatgag
    32941 agaaaaaaat ggaaaaatag cttctcatat tttgccgttt ttgagctaat accgagggac
    33001 agctgattga acgccgttta tcaagaggtt gtgataaagc cgcttcgttt cgagtagtaa
    33061 gaaaaatttt gtaaacatgg gtttccacat ttttgcataa atttgactta ctaccgagaa
    33121 actggctttt gaacaccgtt tatcaagagg ttgtgacacg tcttttgtca caacctcttt
    33181 tatttttgct tcactgtaac tgctacaata tcaccgattt cttttccgat gtttttacga
    33241 atatcttttc gtagtccaag gatgtagcag actgaaccat ctggattttt cacgcccata
    33301 ttcacgatac tgccttcata cggcacattg tcaaaagttg cttggacttt aactcttcca
    33361 gcaccgaatt cttttcttat atcatacgga aaaataatat atgccccgcc cttgccgact
    33421 tcggaagcat agatttttga ttcaaaagaa taaatttccc tcattttatt tctcctattt
    33481 tttacatcta gtatagcata gcaaaaaaaa gaaggaactg tgacaaaagt cttgtcgcag
    33541 ttcctttttt cgaataaacg gtgttctcct gccaactcct cggtcacaag tcacaatagt
    33601 caacaaacat gagaagctgt tttttgaaat tgctccttgt gactcagagt taaacggcag
    33661 gctcacaacc tcttccttaa acggtgttca aaagcttgca tctacggcac taagcccaat
    33721 cagatgaaaa atatggagtg ctatttttat ctgattgttc ttactgcttg atgcagagca
    33781 gctttttcac aacctcctac atggtgttca aaatattatt cgccttttgc ttctttcact
    33841 aattttgcga atgcttgttg ttggaattca gcagctaagg ctttcgtacg ttgttcttgc
    33901 tctgctttgc tcatttttgg attttcagtc attgctttta ccataccgtc ttgaacataa
    33961 gcttttgctt cactttccat cgtactttgc tgtttcttca ctaattcagc taacttggct
    34021 gcttggtccg tacttaattc tacccatgtc tctgggattt tgaatgtatt cactcggctg
    34081 tcatattcgt gattgttatc agcaatattg aaccagaatt tatacatgtc gtttttgtat
    34141 tcccaataag tagttttcgt cactttttca gcatcgccgt ctgtcttttc tactttattt
    34201 gtttcgttat ccgtaccagt tgcttttggt ttttcttgtt tttcatttgt tcggtaaaga
    34261 tacacttttt cttttccatt ccctaaagct ttatacaaaa gcatatctgc tccttgggaa
    34321 tcagcactgg aaacaatttt ttctgttttt gtttccgtta ctttttccat tccaaagtga
    34381 ttggacaaat tagcgacgat caaacttagt gaagcgacga agattagtcc gaaaatcaaa
    34441 gataaaaagg tttgccatgt ttttttagcg aacacgttcg ttaaagcaaa agcaagcaag
    34501 ctgacaatca aaactccaat aatcatgcat tatcccccgc tttcattaga acaggttctt
    34561 ttttcttcaa taaaaaggca ataataaagc caagaatccc aaagatgatc gctacgataa
    34621 acgcggcatg gtaacctgac agtgtggcat tgattgcctg atctttataa gctaatggcg
    34681 tattatccaa tacagatttg cttgggatat ttgcttttgt cacattcgtc aacacactga
    34741 tcaaaatagc tgtaccaatc gagcttgcga tttgacggaa tgtattattt accgctgtcc
    34801 catgactgat caagttattt ggcaatgcat tcataccaga agtcgttacc ggcatcatga
    34861 ccatggagat cccaaacata cggatcgcat aaaggatcac gatatataaa actggagtcg
    34921 tttttgtcaa gaaagcaaat ggtgcagttg ccgctgtcaa aatgaacatc cctgtgatgg
    34981 ctaaacgttt cgcgccgtat ttatcgaaaa tcgcacccgt cacaggcatc atagccccca
    35041 tgatcaatgc acccggcaac aacatcaagc cagaatggaa tgctgattct ccacgaatat
    35101 tttgaatata caatggtacg accatttctg cccctaccat cgccatattt gttacaccag
    35161 ctaaaacagc tgcaatcgtg aatgtagatg atttgaatac acgaagttcc aagaatggat
    35221 gttccaaatg taattgacgc catgagaaca aggcgatgaa aatcacacca acaactaaga
    35281 aaccaattac tttcaagctt ccccagccgt catctcctac actagaaaat ccgtaaagta
    35341 aactaccgaa tccaatcgtt gataaaatag cggataaaat atcaatgcta ggatttgaca
    35401 atggaataac acttttcatt aggaagaatg ctaaaaccaa gacaagaaca acgattggca
    35461 gtaccatacc aaacaagtca cgccaatggt agttatcaat gatataacca gataatgtag
    35521 ggcctaaagc aggagcaagt ccaataacga tccctgacat ccccattgct gatcctcttt
    35581 tttctggcgg gaaaatagat agcatgatat tttgcaataa tggcatcgat actcccacac
    35641 cgcaagcttg gatcaaacga ccgattagta atgtactaaa attaggtgct gtaaagcaag
    35701 taatcgttcc gatcaaaaag atcgtcatgg cagaaagata taaatttctt gaactgaatt
    35761 tattgatcag ccatgctgtt attgggatca tgatcccgtt gactagcaag aaaccagtcg
    35821 ttaaccattg cacatcagac gctgaaatat cgaaagcttt catcaatgta ggaaaagctg
    35881 tcgtcaataa ggtctgattc aaaacggtac aaaatgtacc aattaataag acaacaacta
    35941 aaagtgtccg attatatggt tttccgtaaa tatctacggg ttggttgtta ctcatatttc
    36001 tccttctttc tgaatttttt ctgaaactac tagaatactt tagtcctaaa ttcgctattt
    36061 gtcaacctac ttgacacata agttaatacg gatataatta agggaagcaa gaggacaaaa
    36121 ggagtgacaa aaatggttgg ggcttccctt aaacgtttgt tggaaaatga tcaattggtt
    36181 gttggcatca gtgaattaag tgatatcgta ggtgtgtctc cacgtcaatt aaggtattgg
    36241 gaacaaaagg gattcattcg ttcgatcgaa gctgatgcga attgtcctag aaaatatcgt
    36301 ttacctacag tcataaaagt agaactgatc aaaaaatatt tagatgacgg atttactttg
    36361 tcaaaagctg cagaaaaggc agaaatccgc caaaagaaaa tgcaccatgt ccgtaaagtt
    36421 ttttcaaaag caatcaaaga tatcgaattg atcgacgaac gctatacgat tttacaaatc
    36481 ggtaacttca aagaagagaa tgctaagatg tacatcattc atgacaacga gacagacgaa
    36541 ttaacttaca agctccttcc tgtcgatgaa aaagctgact acgaacagtt gttaaaagaa
    36601 ctctaaacgc cactaatctc ctaagtacca agctttttaa taagtagatg ctacataaat
    36661 acttgaaaaa aggcctgttt gaacataaga atatccgaac ggtgatctgc gtttctttca
    36721 tatagaaagg aattctccat cactgttcgg atattttttt atttttttcg gttactttct
    36781 tctaatacat ctgttagcca atttgcatat tctgtttccc gattgatcgc atgcgctaaa
    36841 atcaggtagt gtccgtaatt ttcatgtttt tctttttcag taggaaagat cgtttttttt
    36901 cgctctaata gatgaagtcg tttttcttca tgaaggtcac gctgctgctg aataatttct
    36961 actaatgccg gatcattcac gtctttgacg aaatacaatt tcagaacaaa ttcgtctcga
    37021 ttaaccggta gttcattggt gggtgtatga atccactctg ccaattgttc cttcccttct
    37081 tctgttaatt cataaacttt cttttccaat ttttcacctg tgatctctac ttgatgctga
    37141 atgattcctt gctcttccat ttttgcaagt tcaggataaa tctgactatg ttttgcttgc
    37201 caaaattctc ctatttcatt tttgaacgat tgattcaatt catatcctgt catcttcttc
    37261 ttacttaata accctaacaa aatatatcga agtgtatttt ttcttgccat cagttttccc
    37321 tccttgacaa atctttaaat ccattctatc ataaatgagt aatcgaaaac atgtagttta
    37381 ttacatgttt taatttataa ggagatgctt aaacatgaaa gaatttaaag aattggaaga
    37441 ttttattgga actcacttta tctatacgta tgacaatggt tgggaatatg aatggtatgc
    37501 caaaaatgac catactgttg attaccgtat ccatggcgga atggtcaaag gccgttgggt
    37561 aaaagaccaa gaagctgata tcgttaaatt gacggacggc gtattcaaaa tcacttggac
    37621 agagccaaca gggacagacg tggcattgga ctttatgcca aatgaaaaga aacttcacgg
    37681 aatgatcttt ttccctaaat gggttgaaga acatccagaa atcactgtta ctttccaaaa
    37741 cgaacatatc gcagaaatgg aagcagctcg tgaaaaatat gaaacttatc caaaattact
    37801 tgttcctgaa tttgctacga tcacttatat gggtgatgca ggtatagaca atgaagatgt
    37861 tattagcgaa gaaccatacg atggaatgcc agatgatatc cgtagcggaa aatacttcga
    37921 tgaaaattat aaacgagtaa aataaggttg tgaaagagag gttgtgaaat cagcgttctg
    37981 acctgagtat tagagaaaga aacggaaaaa tagttcctca tgttttgccg ttttttgagc
    38041 taataccgag ggtcagctga ttgaacaccg tttatcaaga ggttgtgaaa tcagcgttat
    38101 gctttgagta ataagaacgc tagttagaaa atagcttttc atattttcta ggctagtggg
    38161 cttattaccg agaagcagcc gtttgaacac cgtttatcaa gaggttgtga aatcagcgtt
    38221 ttgacctgag tattagagaa acaaatggaa aaatagttcc tcatattttg ccgttttttg
    38281 agctaatacc gagggtcagc tgattgaaca ccgtttatca aagattgtaa caactgcata
    38341 ttcacacagt taaattagtg acttcaaaat gaaataatgc tcccagcaaa aaattaggct
    38401 gggagcatta tttcgttatt ctgttcatca aaaatcagcg ttttgattcc atttcatcac
    38461 aagttcctcc tcatttactg cttcatcttt ttgctgtgtt tgaattgtaa aaccttgtga
    38521 aagatagaaa tgaatagctg attgattttt ttgatagact gtcaaagtca gtgttttatt
    38581 ggtttctttt atttttttca ttagttgcgt accgattctt tgttgccggt attccctttt
    38641 cacaaagatt cctgcgataa actgatcaat caccccagca aaaccaataa tttcttgatc
    38701 tatttctgct aagtaaatca ctgcatctgg taaagctttc ctaacagatt ctacttgatt
    38761 ctcccaataa gttgatggaa tgaattcatg agaatccaag ttagcatgca gccaaatcga
    38821 tagaacagat tccagttctt tggcagacaa ttttgttgtt gtgcggatca ttttttctct
    38881 ccttacttat tcattgattt taaaataaaa accatttttt tgaagctctt ttacaagttt
    38941 tcgcccctca aaaaagtata tcttctcttg ttttactttt ctaataccaa aagaaacagc
    39001 aactttagga tcatcagctg aaacgattcg ataagttcca ccaggcaatt gatccagctt
    39061 gactttccca tgatggtcgc tttgtactga aaacggcaca ccatttctag taagtgtttt
    39121 tttcttatgt ttcaaaatga atgaactacc atttaccggt ttccctgacg aatcactaat
    39181 aataaatgaa aaatcaagca cttttttact taatctatac tgatagatta gtcgtccgat
    39241 aaacactaac agtatgacta cagctattat cgttcctgca agaataaacc attgccgcat
    39301 ggttctttcc tgatttcctt ttccttcttc tttttttacc gattcgttat aaggaatccg
    39361 atgtcctgtc actagcaaac gatgcgtgtt gatcatatac ggcgtacatg taagcaaggt
    39421 aactaagtct tctccttctg aaatcgttag aacagacgtg tcatctggca gtaccacttg
    39481 tatattttta acttgataag ccaatttctc ccccaaaaca gtcaaaataa acgtgtctcc
    39541 gttttctaaa cgatctaatt cggtaaataa ccgtcgatta ggtaaaccgc tgtgagcaga
    39601 gatcactgaa tgcgtcgaat ttccaccaag cgggaaagag gttccttgca agacgcctgc
    39661 tccattttca aggatcctac cattgagccg atcataaagt gaaatattta attggatctt
    39721 aggtatattg atacttccga tcagccattc ctctaattgg ctggatgttg tactttcatt
    39781 tctgttcttt tcattgaaag gatcagtacc aggattgaat ccttggtcag ttaatcgttg
    39841 gtttttctcc tccattttct ttcgctgcac ttcaatttca gctgcggtcc gtttttgtac
    39901 ttgttcgata cgtttttgat caataaaact atttaaagaa tccacataaa atggatataa
    39961 agcgatcagt aaccctacga cgatacatat taataaaaac aaacgaaaca aaagtcgacg
    40021 agactgtttt tgcttactct gcttcacatg tgtcctccct tgcaagtttt tttgttcttt
    40081 cttttattat atgggttcag gaaaaaaata gaaaatgaaa gccgatgagg ttgtgaaaaa
    40141 gctgtcctgc atcaagtaat aagtacagcc caaaaaaata gctactcata ttttttgttg
    40201 ggttgggctt attaccgcag atgcaagctt ttgaacaccg tttaaggaag aggttgtgaa
    40261 aactgcgtta tgctttgagt aataagagcg ctagtcagaa aatagcttct catattttct
    40321 aggctagtga gcttattacc gagaagcagc tgattgaaca ccgtttaccg agaggtcatg
    40381 aaaaagctac tttgtttcga gtattaagaa aaattctgtt tcaaaacaag gagatgcaac
    40441 aaaacttatg tcgcatcctc tctccttaga actttcactt atgtttttct tgtaaaattc
    40501 ataaatattt tcatgaattt tctaatttct tgcctacctc tcgcatagga tatatgatga
    40561 atttatctaa agtttgcaaa ggagttcgac aattgaaaaa atatggccca tttttagcaa
    40621 tttttttcat tgctttggca tttctcatgc ctcatttatt cacacataaa ctaattttgg
    40681 gtgctgatgc cccattccat tacaatcggt tctatgatgc cgcgcaacaa attaaatatg
    40741 gggatttcca ttattttcct tccctttatg gattccagca aagtggcagg atcgtgaatg
    40801 ccgtttacgg cccatttttc gcttatttac aaggattgat cgtgttgctt gcaggtagct
    40861 ggtttcatta tcagattctt tcaaatttca ttctttatct tatttcagga ttttctatgc
    40921 tgattttact gagatatgtc aatgttcgaa attgggtaag tgtaccagta gccgttttat
    40981 tcatgagtac gtattctatt caatactggt ctatcaacca aggattcact agctggggga
    41041 cttgttttta tcctttatgt atgatcccta ttgctgattt cgtccttcat aaaaagttcc
    41101 ctgttatcaa agtcgctgtc tcagtgggac ttatgacaca gatccattta ctgtcttcga
    41161 tcatgttagc tttgatgtat atcccttttt atctttatta cttttttaac cagactgaaa
    41221 aaggaaaagc actgcttcaa ctgattaagt cggtcttgct ttattttgtt ctgacagcaa
    41281 atatttgggc aggattagct attgtttaca gtgggaataa gattcttcct ccctttgtta
    41341 acagagaaat gagtcaaaag gcgatagatc tggatggcag ttattggctc cattacccta
    41401 aggcctttcc tatattgata ttatcaggtt ttttgctttt tattttcttt caacaaaaga
    41461 acaccttatt ccaaaaaatc gtgttgtaca caagtcttgt tttctttttt ctttctacta
    41521 gcttgattcc atggacgaca ttgatcgaaa aaaatgtgcc ttttattagt ttgatccagt
    41581 ttccatttcg atttttcgtg ccatttacgc tattgcttct actttacctt gccctttcac
    41641 tgaaccagtg gtctgaacaa aagtggttcc gtcttttaag tatatttggc attcttattt
    41701 tttcagcaca gacgatccag aacttatacc agcatctgga aaagtgggaa aatgaaacat
    41761 ttgtcagtcg acatacttat ctattcgata cgccggaaga agcaaggaaa acattcttca
    41821 gcaaagatat gtctaccagc ttgttcgttt tccaaaaaac cacacctgac tatctgccaa
    41881 tctataagga gacaaaagac aataaatacg accggtataa cgaagaaata ctagaaaacg
    41941 aaacaacttt tataaaaaca catccaggcg gtcttttgac aatcaagtgg aaaaacactg
    42001 gggacaaaac tgttcatatc cctgttatcg tctacgatcg gactgtgcta cagcaaaatg
    42061 gaaaaacatt gactgattat gaagtaacag atatcgggac cccaatcgtg aagcagcaaa
    42121 aaggaatcaa cgagctcacg cttcattatc aaacgccaat ctatttctat ttcattcttt
    42181 ctcttacttt gattggctgg tttaccttgc tatgtttatt tatttatcat agatacaagc
    42241 ttttacgtgc ttaggcaaaa gggataaata catccgatca aaaaactctc caaacggtat
    42301 aatcgtttgg agagttttat tttaatcagt ttttttatgt tatatgttat attttttatt
    42361 cgttcacatc taattcgatt tccaccccgt agtgatcact gatgattgga ctatcgatcc
    42421 catcaaaaat ccgttgatat tttttaacct gcattccttc agggacgaaa ataaaatcta
    42481 tacgcaattt ttctgtattt tgttcccaac catctatttt cttttccaca gtagctgctt
    42541 ttcctttttc attcgcgaca acatacgaat cttgaagaag aaggcaactt tctcttacag
    42601 tataataacc ttgagagtct actggattat tgaaatcacc taggaaaaaa agtggtacgc
    42661 gagtttccaa aaagtagttt tccaagtttt tccactcaaa ataaaagcca ctttttttat
    42721 ctgtccacca agaaaagtgg cagctcgaga caaaaatgtc ctgatcatct atctttgttt
    42781 tcccaatcaa gatcttgcgt gtctgataat cttctttctt ttgaaattgg gagacggtaa
    42841 ggacctgact ttccaatgtt tttttcgtaa gcagtgcatt tccttcttca tatttatcat
    42901 aaccgatgtg gctcatttcc caactccaaa aatactcttt tccgtgttcc tttaaaagct
    42961 gaactaaacg gtaggcaaaa ttatctttac ggataggtac ttgattcttt accggacaga
    43021 acttcattag cttcgcaggt tctacttctt cagattccag taattggttg atttcttgta
    43081 aagcaatcac ttcataatct tctaacagga tcttatctgc taattcttgc aattttttct
    43141 ctggttctgg ctcaagccag ctatgcgtgt tgagtgtcat gaatttcatt ggttttctcc
    43201 ttgtcttcat ttcgaaacaa aagggttgtg acaaaatttt tgtcacaacc tctccagcaa
    43261 atagtgttct cctgctaact cctcagtaat aagctcaatg gaccaggagc tattttttgt
    43321 ttggctgttt ttatcacttg gtgcagggca gctttttcac gacctctcca ctaaacagta
    43381 ttcaaactgc tgcttctcgg taataagccc aaccaaacga aaaataggag gagctatttt
    43441 tgtttggctg ttcttatgac ttgatgcagg acagcttttt cacaacctct ccttacattt
    43501 taatggagcc gatcacttta ccagctgtca ctgtacctaa ttgcttgatc actacttctt
    43561 ctactttatc gtttgtaaat acgatcatga tcgttggatc tttttcttcg ttttggatca
    43621 catcaagatc catctcagct aatttcgttc ctgttcctac ttcttggcct tctttgacag
    43681 caatctcaaa agctggctga ttcatttgga ctgtatcgat tcccatatgg atcaaaactt
    43741 cgataccatc tttcgtttcc agcccaattg catgtttgct agggaaaata cttgtcactt
    43801 ttccagcgat cggcgcaaca acttctcttg atgttggaat aacagcaaag ccgtcaccca
    43861 tcattttttg tgagaatacc ggatctttta cttcagataa aggaatcact tctccagaag
    43921 ctgcggaaac tagttcttgt tctataccta agtattgctt actacctgct tgtccatttc
    43981 ctgtagaaac catttctggc tctggaatct ctgctcctga ttgcagcaga tcttcgatat
    44041 ctgatttcaa gacatctgct tttggtccat aaactgcttg gactccattg tctttgacga
    44101 tcaatcccat cgcccctgct cgtttccagg cttcttcagt ccctactttt tctcgatcat
    44161 ttacacttac gcgtaaccga gtcatacaag catcgacatc tttgatattt tcttttcctc
    44221 ccagcaaatg aatgatctgg accacttgct gatctgctgt tcctgttccg ctgttagata
    44281 caacggtttc ttcactgtca ttgtcgtaat ttccgttacg tcccggtgta gcaaagttga
    44341 attttttgat caagaaattt gctaagaaat acgtaacaac accaaaagcg atcacacaca
    44401 acacgaagtt gataagatct ccacctagac ccgctttgat agctaacggt gtccgagtca
    44461 gcaattcgat attcccaaat gaatggaccc gcaatggcaa gatatctgcc atcgcaaatg
    44521 cagccccttg gatcactgaa taaatgacat ataatggcac agcagcaaac ataaacatga
    44581 actccaatgg ttctgttaca cctgttagaa agacagccaa cgctgctgaa aaatacattg
    44641 atttatatct tgctttctta tcaggatcga cattacgata catcgcaaaa gccattccca
    44701 tcaagatacc tgaagaacca atcatttgtc ctactttgaa acgagccggc gtccagttat
    44761 gcaacacaaa ctcatattgc gacatatccc ctgcaccttt aagattcact aaatcagtgg
    44821 cccaagccaa ccataacgga tcttgcccaa atacttgtgt ccccgcctgt gcgcctgata
    44881 aaatctcata cgatccgcca agctgtgtat agttgatagg aatcgtcagc atatgatgca
    44941 atccaaatgg caatagtaaa cgttctaatg ttccaaataa aaacggtgct agaatcggtg
    45001 cgctttcttg tgattctgca atccataaac caaaattatt gattccagcc tgtacgtttg
    45061 gccacaccac agcaagaatc aatgccacga ttgttgacca taagataaca acaaacggaa
    45121 caaagcgctt tccattgaaa aatgacaaag catccggcaa ttttctataa ttatagtact
    45181 tattataagc cattgccccg acaaatccag cgatgatccc tacgaatact cccatattca
    45241 aagctggtgc ttccaataca cttgtaaaaa atcctttaac catgatcttc gtaccgaaca
    45301 gagtgtgggt aaatgcatct tcattcgcaa gcatgtcact tgtgacacca aagatagccc
    45361 cagtgatccg attgattaaa ataaatgaga tcccagctgc aaatgctccg cctgctcttt
    45421 cttttgccca acttcctcct attgctaaag caaataaaat atgaagatta ccaataattg
    45481 cccaaccaat attttcaatt actccgcccg ttgtgacaag cggcgtccaa tcaggattga
    45541 tcaagggaat tgatttccct atactgatca tcaacccagc tgccggcata actgctacca
    45601 caaccattaa agcctttcca aatttttgcc aaaactcaaa actaaatatc tttttcattc
    45661 cgtttagctc ctttacgcaa tcggtttcgt taaacgtatt atagcgtgcg ttttcttttt
    45721 tgtaaatgct ttatttttta tttttctgtc tataccattc tataaaacct ataatacgtg
    45781 tgttcccttc tataattttc tcctaaaaat ttattttttt aagctttttt ctatgaaata
    45841 ttttcttttg tctattgact tgtgcaatcg gttgcgttta ttatgaacgt ataaaacagc
    45901 tcattaggag gagaaaaatg aaacagatca aacgactatt tgctattgat ccatggaaaa
    45961 tcagcacgac acaattagat aaaaaaaatc ttcgactgca agaatcttta acaagtattg
    46021 gaaacggtta tatggggatg cgcgggaact ttgaagaaac ttactcaggg gaccaccatc
    46081 aaggtactta tttggcgggt gtctggtatc ccgataagac acgtgtcggc tggtggaaaa
    46141 atggttatcc agaatacttt ggaaaagtga tcaacgcctt gaactttatc gcgatagata
    46201 tttcgatcaa cgatcagctg atcgacttgg cttctttgga accagaagac ttttactggg
    46261 aattagatat gaaaaatggt gtattatctc gtacattcac aatcactact tctactaata
    46321 aagtacgcat ttccttcgaa cgttttctga gcattgtcaa aaaagaatca gcttatatct
    46381 atttaactat agaaatgctt gaaggtagcg gaacagtcaa actcgtatca aaattggatg
    46441 gaaatgttca aaacgaagac agcaactatg atgaacattt ttggaatgag attgatcgtg
    46501 gaactataga agaaatcggc tatttgacga ctaaaactat tccaaacaac tttgggattg
    46561 aacaatttac tgttactgca gcaatgcgcc atttcgttaa tggaaaatca gtcatccctg
    46621 actatcacga agatacttta gcattacatg gttgcttgtc tgcagaatta tctcaaggtg
    46681 agacatggtc agtggaaaaa gaaattatcg ttcttactag tagagatatt ccagaagcgc
    46741 agcaagcaga aaaagctgtc tcagaattaa cgaaccagac aaacaattat atccaagcaa
    46801 aagaagagca aacagcggct tgggcagaac gatggaagct tgccgatgtg gtcatcgaag
    46861 gagacgaaga agcacaacaa ggtattcgat tcaatttgtt ccaactattc tctacttact
    46921 acggcgaaga tgaacgattg aatatcggcc ccaaaggatt cacaggagaa aaatacggcg
    46981 gagccactta ctgggataca gaagcgtatg ctgtccctct ttatcttgct ttagccaaac
    47041 ctgaagtaac taagaatctg ctgaaatatc ggcataatca actgccgcaa gcaatccaca
    47101 acgctcagca acaaggatta aaaggcgcgc tttatcctat ggtcaccttc actggtgtcg
    47161 aatgccataa cgagtgggaa atcacattcg aggagattca ccgaaatggc gcgattgcct
    47221 atgcaatcta caattatacg aattacaccg gcgatacgga atatttgaaa aatgaaggac
    47281 tggaagtttt agcagaaatc gcacgcttct gggcagaccg tgtccatttt tcaaaacgag
    47341 caaataaata catgatccac ggtgtgaccg gcccaaacga atatgagaac aatatcaata
    47401 acaattggta tacaaatacg atcgcagctt gggtcttgcg ttacacgcga gaaaattatt
    47461 taacttatca aaaagaagct gctatcacta tcagcgaaga agaactagcc aaatggaaag
    47521 atatcgcaga gaacatgtac ttcccagttg acgaagaatt aggaatcttt gtccagcatg
    47581 acacattctt agataaagat ctcatgcctg tatccgatat tcccacaagc gatcttcctc
    47641 tgaatcagca ttggtcttgg gacaaaatcc ttagatcttg cttcatcaag caggcagatg
    47701 tactacaggg gatttatttc ttcaatgata cttttacaaa agaagaaaag caaaaaaact
    47761 ttgatttcta tgaaccaatg actgtccatg agtcttccct ttcgccaagt atccattcga
    47821 ttttagcagc agaattagga atggaaagca aagctgtaga aatgtaccag cgaacagctc
    47881 gcttggattt ggataattac aataacgaca cagaagacgg cttgcacatc acttccatga
    47941 ctggtagctg gttgtcgatt gtccaaggat ttgctcaaat gaaaactgcc catgatcagt
    48001 tgagattcgc accatttctg ccaaaaactt ggaaagctta ttctttccat atcaattatc
    48061 gcggacgttt attgttcatc tcagtcacag atgaacaagt tactttcgag ttattagaag
    48121 gttctcctct agaaatttac gtctatgaac agtcttattc tttagcggat cgtctagaaa
    48181 taacgctaag aaaggaggaa gcaaatgttt aaaggggtat tgtttgattt agacggtgtc
    48241 attaccgata ctgctgaatt ccattatcgt gcttggcgaa agcttggtca ggaaatcggc
    48301 attacgatcg accacacatt caacgaacag ctaaaaggcg tcagccgaga agactcactc
    48361 tctttgcttt tagcttatgg cggaaaagaa cactcttttt caaaggaaga atttgcagaa
    48421 ttagcgaaaa gaaaaaacga ttattattta gagatgatcc agacgatcga accaaaagat
    48481 gtcttccccg gggtcgtgcc tttactggat tctttaaaag aagaaaaaat caagattgct
    48541 cttgcttctg caagtaaaaa cgggccattc ctacttgaaa aaatgggtct tacaccttac
    48601 tttgatgcta ttgccgaccc ggcagaagca acaaacggaa aacctgcgcc agatatcttc
    48661 ctccttgcag caaaagctgt cggactaaaa gcagaagaat gtatcgggat cgaagacgcg
    48721 caagccggta tccaagccat cctctcaagt ggcgctcaac caattggcgt gggacgtgct
    48781 gaagaccttg gagaggagat cccgcttgtc cctgatacga cttttcttac gatcgattac
    48841 ttgaaagaaa agtggcatga ccatggataa tccagagatc tccgtcgtac cagttccaga
    48901 gactgaaata aagaaaatca cattgaagaa cgactactta gaagtcgttc ttctcaatta
    48961 cggtgcccgc ctgcaccaaa tcttcgcacc agacaaagaa ggaaaatcag aaaatgtttt
    49021 attgtcttac gatcgtttcg aagatgttct aacagacaaa agcttttttg gagcaactgt
    49081 cggacctgta gccggaagga tccgggatgc ttcttggggt gagcatagat tggagaaaaa
    49141 ctgcggatca caccatatcc acggtggcac gaaaggctgg tctttccaat tttgggaagt
    49201 agaagttttc aaaactccat catcaatagg tgtggtcttt tacttaaaag atgaattttc
    49261 tacctatcca ggaccaatca ctgctacgat cacttaccgt ttaacaaaaa acgaattaga
    49321 gatgacaacc tctgctagta gccttgttga aaccatctgc aatccgacca accatgccta
    49381 cttcaacctt tcaggaaatg gaacaagaga catctatgaa catcagttaa cggtcttttt
    49441 agatggtgtg cttgaattag atcaagaaaa actgcctact ggaaattgga caaaaaaaga
    49501 aaaactgcca atcgacttta gaaaatcccc aacactgcaa gagatccttg catgttatcc
    49561 agatggacta gatgatgtat ttcttttgca tcatcctagg ctttccaaaa cttccttaca
    49621 attattcgag aagcattctg gtcgccaaat gactatagca acttctaata aaagtatggt
    49681 attattttct acgactggat tcgaagctga tttctctgtc aatggaaaac agatgcattc
    49741 aaactacgga ttagcaatcg aaccgcaaga aatccctgat atcgttcatt tccccaaatt
    49801 tggatcgatc aacctccatc ctggtcaaga acggatcagt cagacgattt atcggttctc
    49861 tgcacaataa caagagaaag gtgtttttat catggctatt accgtaaaag atgtggcgaa
    49921 aaaagccggt gttgccacct cgaccgtctc tcgtgtcatc aacgatcatc ctagtatttc
    49981 cgagacaaca aagaagaaag tccgaaaaat tatggatgaa ctaggttatg ttcctaacat
    50041 gactgcccgc aatctaggaa aacgcatttc cagtgccatc ggcgtaatct taccccctct
    50101 tgattcaaaa gagcggatcg gtaacccatt ttatcttgag atcatggaag caatcaacga
    50161 agaagcgcgg aattatgata tgactacagc aatcgctact gctaaaaatt ttgaattgct
    50221 gttagagaac gtccagcgta tgcatttaca aaaacaagta gatggtttta ttctagtgta
    50281 ttcagatagt caagatactg tcattgatta tttataccaa aaccacatcc ctttcacttt
    50341 gatcggacag ccttatcatc atgagaacga aatcgtttat gtagataatg ataaccagct
    50401 tctaggtaaa caagcaacag aatttttgat ccagaatgga cataagaata tcctgtttgt
    50461 gacaaacacg actcatgaaa gtttgtattt cgaacgatat ttcggttatc aaaaagcaat
    50521 gatgatggct ggtcttcctg cgttatccag tgtagtacta gagcatccgg aggattatct
    50581 gtcctttgag aaaacgttga aagaaaacga agccacagca ttggtggtca ttgacgatat
    50641 cttcgccctt cgcacgatgc agttggcgca aatgtatggc tatgtcattc cagagacact
    50701 ctccgtcatt agcttcaaca actcgatctt ctcaacatta acacaccctt accttacaag
    50761 tatcgatatc gatatctccg aattaggacg tgtcgctatg caaaagctgc gcgaattgat
    50821 ccatgaagaa ttgagcagtg gcgtacgttt ggtcatccct catcgcttga tcaaaagaga
    50881 gacagtcgtt cctttagaaa acccatacta aatagctgac tcactaaata cgctgaccat
    50941 ttatcctatg gtcagctttt tatgtaaaag aagatactac ttctaacaca ttgtttatct
    51001 gtaaaaaaga gcgtgggaca aaagtaaaga acacttttgt ctcacgctct aaacacgtat
    51061 aaacggcgga agcagaagca actccttcgg aaataagctg aaattcacaa aaatttaaaa
    51121 agcaattttc ttgagtttct tcttatttct tggagttaaa cgcttctgtc ccagcctctt
    51181 ttttccttcc ttcaattttt tacacgtcga cgattcaata aaaaaccgcc taatattgta
    51241 aagacaggtg caagaatcga gaaaaaggcg aatggcaagt aatgcaacgc gctaactttc
    51301 atcgttccca taatgaatgt gccgctgact ccccacggta cgagagaatt gacggtcgca
    51361 cctgaatccg ctagtgttcg tgtcaaatag gtttttgata agccaacgtc atcaaaagaa
    51421 cgcttgaatg tttctcctgg aagaatgatg gacagatact gttctccaac gatcagattg
    51481 attccgatac agctcaaggc agtaaacccg actaaacgag aaggtcggtc catcttttct
    51541 tttaattctt gaacgatggt atcaacgatc agatatttga tcagtaaccc acctaatgcc
    51601 aatgcaagta aaatcaaact agcagaacct aacatactca tgatcccgcc tcgagaaagc
    51661 agttcatcta gctttggatc aggtgtattt gcgacataac cattcatcaa gatgtctgct
    51721 gcttttccga ccgtcaaact tttctcatgg ataaaagaaa gaacgagagc agctgtcgat
    51781 cccgctagta atgtagggat agccggaatt tttttgattg cccccccaaa taaaataact
    51841 agtggaatca atgtccaagg agagatccaa aagctcgctt tcatgttttg gatcatttca
    51901 ttgatactag ctagatcggc tgaatgactg ttatgtccta atatcgtata aaaaatcaac
    51961 gaaaggacga atgctgggaa atccgtataa cgcataccag cgatatgttc gaatagatta
    52021 actcctccaa tacccgctgc caagttggtc gtatctgata aaggcgagca gttattccct
    52081 aaaaaggcac cggaaacgac tgcgcctgta gtcattgcat cattgaatcc aagtaaatga
    52141 ccgatcccca aaaaagcaat tccaatcgtc gaaatcgttg taaatgaact gccgacagtc
    52201 actccgacaa ttgcacaaac aagaaatgct gtcggtaaaa agaaacgcac agaaacaagt
    52261 ttaaatccat aaaccataat cgtagggatg gttccagata aaatccatga agcaactaag
    52321 acaccaatca aaagaaaaat caggattgga atgatccctg gagtgattcc tttgatgatc
    52381 ccgtcatgga tctcatccca tgtgaacttt ttaaatctgc cataaaacaa caaacacatg
    52441 aaagctgcaa ggatcgggat atgtggcgag agctggaatc cgatgatcag tactcctagg
    52501 agtgccaaca acacgatcaa tacagcgata ctttctttta aagaaatatt tttattcatc
    52561 gtcgatctcc tatttcaaat gaaaaggccc tgccatgaaa aaactattca cttggcagga
    52621 cctcctacta aatcagcgac aaaacgtcgg ctgaaagact tattttttta tttttcttct
    52681 aaactttttt ctacctcaat cccccaagaa tctttcttga agtgattgat gatcaatgga
    52741 ataacgaaca tgaccactgt gatagctgct actaataatg catcactcaa tgtcgctgta
    52801 cctaatgtag caaatacgac aacgatgata gagaagatca gcatgcagct gactacccaa
    52861 gctaatccgt ttccgttttt accaattcgg taaggacgtt cgaattctgg atgtttctta
    52921 cgcattttaa gcaatgaaac agcaatcaaa atgtacacga tacaataaat aacagttgta
    52981 gcatttgtaa gtgtcaagaa tacagcactt acgtcatcca ttacaccata aagcaaagca
    53041 aataatgaaa taacgattga ttgtgttaga acgacatttc tagatacgcc gtatttgttt
    53101 tctttatgga atccgaattt tggtggaagg aatccttcac gagctacttg gatgattgtt
    53161 tttgatggtc cagtaaccca agctgataat tgtaaaagca caccaataaa taccatgaag
    53221 ctgaagatat ttccgatcac ttctggtaag cctaggattt gacagtcaat caagataggc
    53281 tgcgtgatat ttgctaattc catttttcca tctggtacga catttgctac aagcatcgca
    53341 ttgatgacat tcaataaaac taatccgatc aaagcgataa atacgccttt tgtataattt
    53401 tttgttgcgt ctttcaaacg aggcatgtaa acagaactca tttcgatccc aacaaaaata
    53461 aatgtgatac cagctaagta tttcaatgaa tcaatatgtt ccaagtcagg gaaagctttt
    53521 gaccatgaaa agtcacctag atagccgttt gagactagtc cgactttgaa ggctgccaaa
    53581 acacctaaaa cgaacatgat gactactggg atatataccc ctagccatac accgatgttc
    53641 ccgccgactt ttgccatatc gaatttcaag ttcaagatcg tgatgatcca gtagataact
    53701 aaaatacaac ctaaaacgaa ccagtgatta ttgccaagtt ctacattacc aaatgtgttt
    53761 cctaacaatg gtcctaaagt agaagcgacc attaccatac ctgggaacat ttgcacccat
    53821 aatagccatg caacgacaaa tccccatttg ctgcccagtg ctgtttttac ccataactga
    53881 ggaccgcctt cttgaggaag catcgtggaa agctcaccgg aaaccattga tatcggaccg
    53941 gcaaaaaaca aaactgcaaa aattgaataa aaaatcaatg tccaaccgac tgcggctaac
    54001 gtaggaatac tccgaaccgt tgcacacagt gccattgtca gaccgataaa ggtcccaaga
    54061 cccattttac ttacttcaga tttactcacc gttgacactc tccttgattt tttggataaa
    54121 ataacggtgt ctttgaagta gtttcagcaa taaacgaaac aattcagcga atatttgagg
    54181 ggattctttg agtttattgc ttgaagggtt tcttcaaaga caacctcaaa acaaagggat
    54241 cgaagagctt aggtctcccc ttgctcttca gatccaaaca tgcgtcagaa acagttagta
    54301 ttcaagctgt tttctaacat gattaccttg cttattttgc ttcgcttgcc aataattggt
    54361 ctgcgtagat tttttccaat ttttcttgaa gagctgcttt gattttttca gcatattctt
    54421 caaagtgttc ttctttgttc atgtatggtg tcattacgct ggcacgcaat acagttactt
    54481 ttccggcacg gttccattct tcatctgaga atcctagttg gttcacaaat tgtaatgggc
    54541 tgttgccata gtctgggata gcaaagtcag tatgtgaagt taagaactca ttaccgtaaa
    54601 tgcttccttt cacgtatgaa gaataatcat atacgtcatg gttcaattta ttcattgcaa
    54661 ctaagtcatc gttgcctttt tctttgaata catagtctac catattgaaa tctggataag
    54721 ttaatggatg aacttcgatt tctttgtctc ctactttaaa tgacaagtca ttcaagaagt
    54781 tgtagaaacg atgtgcacct tcgattgatg cacccattaa tttaccatat cctgtgacat
    54841 tcaaaggtaa gacatggtgt gctgcccaaa cgctggctgc tgttgcccct gcttttgaac
    54901 cttccaagat ataagcccca agtaatgctg ggatatctgc gcctttttca aatacatatg
    54961 tcgcaaagta agagataacg tctctcatgc ggatatcttt gatgacgata ccaccggcag
    55021 aatatggaac atagcccatt ttatgtgggt caatcgttac agattctgct tcttcgattg
    55081 ctttatatgc actgtgtact tcttctaaga tataatcttt gttttctgta aagacattgt
    55141 atttgtaatg aacatctttt aaatcttcaa atggaatgaa gttgttgtct tcgtctaaga
    55201 aaatcgcacg gccgtatccg ccataagcag catctacgtg taagtagaag taaataccgt
    55261 ctttttctaa tacgcgacgc aatgcaacga ttttatcgat accgtcgatt gctccttctt
    55321 ctgttgatcc tacaacaccg actacaccta ggattggtgt tttttcagct gctagaccac
    55381 gaacgatttt ttcaagttcg ttgatgtcca tgcgatagtt gtggtcaact ggcactggaa
    55441 tcacttggtc taaaccgata ccgatgatgt cggcagcttt tagccatgaa tagtgtttag
    55501 tttgtggaac caaccatttt cctaattttt ctaaatgttt tccgctacgt gctgagtgag
    55561 ctttgatttc gtcgattttt tctgggacgc tgtctaacag attcatgatt tcttctgttg
    55621 acaagttcat taattcccaa tcgctttttc cagcaactag ttcaggtgtc acttctttca
    55681 ttgcaagcgg caatgatttg atgttgcggg cataccaaag tccttctaag tttgctaaag
    55741 aaccatcagc aacgatgtgg ccccagccat ctttatagct cattaatttt gcaaattcca
    55801 ttcctacttc ttcttccatt tggcttgttg caggagaaga ttcataggca acgttattac
    55861 cattccatag catagcaaaa ttgtacgcta gtaaagatgg catcaatgtt tcagagttca
    55921 tatgacccca gtaacgtccg gcattatgcc aaggaacgga atgggtacgc atccgcgctg
    55981 aaatttctga tagaacatcc tttgttttat tcacagtgtg ttcaaaacta gcactgcttt
    56041 tttcttctgg cgtaataata ggcatgtctt gaggcatgta gttttgacgc cagcctaaat
    56101 gttcatccac caattcattc aacaaagctt tatagatttg gccgttctca gctttgtccc
    56161 caatgaatag ggcatttagg tttagatctt tcgacaatga ttcactcata gtgaaaccct
    56221 cctaaaaaaa tatttaaatt ttgtcgagcc ctacattaca cctgttcttc tattctgtaa
    56281 actaagtttt ggcctgattt ttaatcatat tttaatatgt atcaattatc cgaattgttc
    56341 acacttttga aataattaaa aaaaacgagg gaatttacaa atgtaaactc cctcgcaaag
    56401 attgtattaa cgacaaccag cgttctattt taggatgggt ttcaaaattg gaatgttgta
    56461 atagtatttc cctttttcaa ggtaaaaact tactaaattc taatcaatta ctttggccaa
    56521 aaagtaattt ttcttacctt ttcgaataac cacaaactta ccatcgaatt catcggatgg
    56581 atttatgaca aaatttaaat cggtaacgcg gtcaccgtta atacttatag ctccgtttga
    56641 aacatcttca cgtgcttgac gtttagatgg ttcaattttt gtggaaacaa gcagttccac
    56701 gatattttca ggtgtgcttg aaatttcaac gttcggcatt ttaccgaatc cttgcgcgat
    56761 ttcttccgca tttagttctt taatatttcc agagaacaat gcttgcgtta ttttttgcgc
    56821 ttctttcaag tcttcttcac tatgcacaaa tcttgtaact tcttctgcca aacggcgttg
    56881 tgcttcacgt ttctcaggtt ctgtctctac ttttttcgct aagtcttcga tttcttcttg
    56941 agacaagaaa gtaaagaatt tcaagtattt cactacatcg cgatcatctt gattcaacca
    57001 gaattggtag aactcaaatg gtgaagtttt cttcggatca agccaaacgg caccgcctgc
    57061 agtttttccg aatttcgttc cgtcagcctt cagcatcaat gggatcgtta aaccgaacgc
    57121 ttctgcttct ggtccttcta attttcggat taggtctaat ccagctgtga tatttcccca
    57181 ttggtctgct ccaccgattt gcaattgcac atcgtatgtt ttatgcagat gcaaaaagtc
    57241 gatagattgc aggatttggt aagtaaactc tgtaaatgag attcctactt ccaaacggct
    57301 ggcaacgata tcttttgcta acatcgtgtt gatgttgaag tttttaccgt agtctctcaa
    57361 aaattcaagt aaagagattt ttgacaacca gtcgtagttg ttcacaaatg tgatatttgc
    57421 atctttacca aacaattttc tcatttgatt ggaaagtgcg tccacgttat gttgcacttg
    57481 ttccatcgtt tgcaacacac gttctgtttt gcggccgctt gggtcgccga tcgttcctgt
    57541 tccgccgcca atcagaatat atggatgatg gcctgccaat tggaatcttt tcatcatcat
    57601 aaatggaatc aaatgtccga tatgcatcga atcaccagtt ggatcaacgc cgcaataaag
    57661 tgaaatgctc ttttcttcaa cgagctcgcg aagtctttct tcgtttgttt gctgattaat
    57721 ggcgtcgcgc caagttaatt catcaataat attcatttta ctgacctccg tgtagttttt
    57781 ttatgaaagc aggaacctgc tagcatatgt aattaattat ttcttcagga taggatagga
    57841 aataaaaaaa gtcccttggc atataagcca agggacgaaa tctcgcggta ccacccaatt
    57901 tgtatgtcta gatatccaac atacctctcg aacatttaac gctgtcgcgt ggcaatcact
    57961 gccaaagact cctgaaatgt aattcgcttt aaagcatgta ctggtttgca gcgaccacca
    58021 gctttctgaa acattggctt taacaactac ttcgtttcga tcttcgtctt gttattatta
    58081 atatgtgtct atcatagagc gcaacttttt ctttgtcaac agaaaaagga tatttttttt
    58141 aaattcctca ttttttcttt tttgaatccg ctctaattcc gaacatttta ttttcaatta
    58201 ttgttaaaag aaataacttt ttctgtattt tttctgcaat ttatcgagaa gtcactttac
    58261 tttgcctctt attctttctt cgttacaata aggaatggga caagtaaaaa aatgaaaaag
    58321 caagggacga ggtatatgga aaaaaagcaa aaaattattt taggagccac ttctgcttta
    58381 actatcgtta ttttaattct aagtttgttt tttgtcatcc gatcatctac aaaaaaagaa
    58441 ccaatcattc ctgaaaaaaa aataacagaa aaagcaaaag aaccgacaga tgataagcaa
    58501 caactagtta ctcaagcaaa aaatctggct caaagctacg attatgacca agcgattgcg
    58561 ttattggaaa aagatagtaa gaacggatct actgaaacac aacagcttct tcaaacacta
    58621 aaaaaggaga aagaacaact gatcgactgg tctgatccta ctcagatctc tcatgtcttt
    58681 ttccacagct tgatcgtgga cccgcaaaaa gccttccact ctcaacaggc acaaggatac
    58741 aaagattata tggtgactgt tgaagaattc aaccgttcga tcgaacaact ttatcaaaat
    58801 gattttgttt tagttaattt gaatgatttg atccaaaaag acgaacaagg aaatctttcc
    58861 tttaacgggc ttgcgctacc tgaaggaaaa aaaccattgg ttctttcaca agatgatgtc
    58921 agctattatg aatatatgga taattccggt tttcctagcc gattggtcgt atcaaataac
    58981 aatgaaatca aaaatgtcta taaagagaaa gataaagaag aaatcggtga ctttgacatg
    59041 gttcctctga tcgatgcctt tgtcaagaaa catcctgatt tttcttatcg aggcgcaaaa
    59101 ggtaccttgg ccctgacagg ttacaacgga gttttaggtt atcgaacatc aaaatctcaa
    59161 tatggagaca atgaaaaaac aaaaaaagag attaaagaag ctaaaaaagt ggcggaacag
    59221 ttgaagaaag acggctggag ctttgcttcc catacatggg gtcacttgaa tatgactcaa
    59281 gcttcactag aagatgtaaa aaaagacaat gaattgtggc agcaagaagt tgcacctatc
    59341 ctaggaaaaa caaatattct gatttatcca tttggtgcag acatcagcga ctggcagcct
    59401 tattcagcag aaaatcaaaa atttgcttac ttgaagagtc aaggtttcga tattttctgt
    59461 aatgtcgatg cttctacacc agcttgggga caattaggta cggatttcta tcgaaatgct
    59521 cggatcaata tcgatggcat tcgttttcaa tctgatttag acggaaaaaa tcctattctt
    59581 gatccattca tcaatgtcca tgatgtctat gacaaagaag cacgcgaatc tgcttgattt
    59641 tacgtcattt atgaaccaaa aaagccgaac tgacatttta tcgtcagttt cggctttttt
    59701 atgctttatt tcttcttcgg tgcgattccc ttgatcagga cttctgtcca ttctgctgta
    59761 tatggaagca gttttgcgta tatctccggc ttagaaattc cttctaccat tgcttgaaaa
    59821 tagaggatca agaactcatc cgaatatttc aaatccactt ttccttcttt ccgccctcga
    59881 tggaaaagat caagcatgat actgaaactt tcttgcgtat acgcatccat cgcgtcagaa
    59941 aattcttttt tttctttttt tgtatagtat gtcatcaaat cgatataaaa ttgtttgttc
    60001 actcgattga gataacggat tttgttttca ctcatggcaa tcagtgtttc ttcaaatgga
    60061 agattttccg caatcaacgc tttcgcttct tgccctaaat cattcataaa tgcaaaaaat
    60121 acttcataaa tcagcccttc cttgctgcca aaatatttaa aaatcgtcgc tttacttacc
    60181 tgagcgttct cagctacctt atccattgtc actccagcgg ttcctatgtc tgtgttcatc
    60241 aagtcaaaag ctgcttgtaa aatctctttc tttttctctt gtgctctctt ttcaaaaccg
    60301 ttcatttgta gagcctcccg taattttaaa cttttataat atatatagtt caaatttatt
    60361 ctgaggttta ttataactat ctattgagaa agtatcaagc tagcaattcc ttgtttatga
    60421 attcattgac agaaatttat aaaaagaata ttatgtacta aaataataaa aaaagtttta
    60481 taaaaag
//
LOCUS       DAFLWC010000005        58789 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.005, whole genome shotgun sequence.
ACCESSION   DAFLWC010000005 DAFLWC010000000
VERSION     DAFLWC010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 58789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58789
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.005"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(199..939)
                     /locus_tag="L1V17_000290"
     CDS             complement(199..939)
                     /locus_tag="L1V17_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235084.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(1069..2016)
                     /locus_tag="L1V17_000291"
     CDS             complement(1069..2016)
                     /locus_tag="L1V17_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1235085.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            complement(2145..2909)
                     /locus_tag="L1V17_000292"
     CDS             complement(2145..2909)
                     /locus_tag="L1V17_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBN1235086.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIQLMEEASTFLAKNLIKKYK"
     gene            complement(2913..3302)
                     /locus_tag="L1V17_000293"
     CDS             complement(2913..3302)
                     /locus_tag="L1V17_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235087.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            3437..3979
                     /locus_tag="L1V17_000294"
     CDS             3437..3979
                     /locus_tag="L1V17_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HBN1235088.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            4127..4759
                     /locus_tag="L1V17_000295"
     CDS             4127..4759
                     /locus_tag="L1V17_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235089.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(4893..5018)
                     /locus_tag="L1V17_000296"
     CDS             complement(4893..5018)
                     /locus_tag="L1V17_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1235090.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(5152..6045)
                     /locus_tag="L1V17_000297"
     CDS             complement(5152..6045)
                     /locus_tag="L1V17_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HBN1235091.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(6227..7153)
                     /locus_tag="L1V17_000298"
     CDS             complement(6227..7153)
                     /locus_tag="L1V17_000298"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HBN1235092.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(7238..7999)
                     /gene="pflA"
                     /locus_tag="L1V17_000299"
     CDS             complement(7238..7999)
                     /gene="pflA"
                     /locus_tag="L1V17_000299"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBN1235093.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(8243..10474)
                     /gene="pflB"
                     /locus_tag="L1V17_000300"
     CDS             complement(8243..10474)
                     /gene="pflB"
                     /locus_tag="L1V17_000300"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBN1235094.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(10751..13201)
                     /gene="parC"
                     /locus_tag="L1V17_000301"
     CDS             complement(10751..13201)
                     /gene="parC"
                     /locus_tag="L1V17_000301"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HBN1235095.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(13213..15258)
                     /gene="parE"
                     /locus_tag="L1V17_000302"
     CDS             complement(13213..15258)
                     /gene="parE"
                     /locus_tag="L1V17_000302"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HBN1235096.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(15424..15858)
                     /locus_tag="L1V17_000303"
     CDS             complement(15424..15858)
                     /locus_tag="L1V17_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBN1235097.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            15985..16623
                     /gene="plsY"
                     /locus_tag="L1V17_000304"
     CDS             15985..16623
                     /gene="plsY"
                     /locus_tag="L1V17_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBN1235098.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(16755..17630)
                     /locus_tag="L1V17_000305"
     CDS             complement(16755..17630)
                     /locus_tag="L1V17_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBN1235099.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(17712..18503)
                     /gene="codY"
                     /locus_tag="L1V17_000306"
     CDS             complement(17712..18503)
                     /gene="codY"
                     /locus_tag="L1V17_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBN1235100.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(18521..19921)
                     /gene="hslU"
                     /locus_tag="L1V17_000307"
     CDS             complement(18521..19921)
                     /gene="hslU"
                     /locus_tag="L1V17_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HBN1235101.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(19935..20483)
                     /gene="hslV"
                     /locus_tag="L1V17_000308"
     CDS             complement(19935..20483)
                     /gene="hslV"
                     /locus_tag="L1V17_000308"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HBN1235102.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(20520..21425)
                     /gene="xerC"
                     /locus_tag="L1V17_000309"
     CDS             complement(20520..21425)
                     /gene="xerC"
                     /locus_tag="L1V17_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HBN1235103.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(21623..22999)
                     /gene="trmFO"
                     /locus_tag="L1V17_000310"
     CDS             complement(21623..22999)
                     /gene="trmFO"
                     /locus_tag="L1V17_000310"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HBN1235104.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(22968..25046)
                     /gene="topA"
                     /locus_tag="L1V17_000311"
     CDS             complement(22968..25046)
                     /gene="topA"
                     /locus_tag="L1V17_000311"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBN1235105.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(25168..26025)
                     /gene="dprA"
                     /locus_tag="L1V17_000312"
     CDS             complement(25168..26025)
                     /gene="dprA"
                     /locus_tag="L1V17_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBN1235106.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(26081..26848)
                     /locus_tag="L1V17_000313"
     CDS             complement(26081..26848)
                     /locus_tag="L1V17_000313"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBN1235107.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(26841..27701)
                     /gene="ylqF"
                     /locus_tag="L1V17_000314"
     CDS             complement(26841..27701)
                     /gene="ylqF"
                     /locus_tag="L1V17_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBN1235108.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            27961..28359
                     /locus_tag="L1V17_000315"
     CDS             27961..28359
                     /locus_tag="L1V17_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBN1235109.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            28638..29138
                     /locus_tag="L1V17_000316"
     CDS             28638..29138
                     /locus_tag="L1V17_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBN1235110.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(29221..29772)
                     /gene="lepB"
                     /locus_tag="L1V17_000317"
     CDS             complement(29221..29772)
                     /gene="lepB"
                     /locus_tag="L1V17_000317"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBN1235111.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(29924..30151)
                     /locus_tag="L1V17_000318"
     CDS             complement(29924..30151)
                     /locus_tag="L1V17_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HBN1235112.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(30148..30666)
                     /gene="msrA"
                     /locus_tag="L1V17_000319"
     CDS             complement(30148..30666)
                     /gene="msrA"
                     /locus_tag="L1V17_000319"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBN1235113.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(30686..31399)
                     /locus_tag="L1V17_000320"
     CDS             complement(30686..31399)
                     /locus_tag="L1V17_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HBN1235114.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(31402..32298)
                     /locus_tag="L1V17_000321"
     CDS             complement(31402..32298)
                     /locus_tag="L1V17_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBN1235115.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(32456..33298)
                     /locus_tag="L1V17_000322"
     CDS             complement(32456..33298)
                     /locus_tag="L1V17_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBN1235116.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            33430..34083
                     /locus_tag="L1V17_000323"
     CDS             33430..34083
                     /locus_tag="L1V17_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBN1235117.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(34146..34673)
                     /locus_tag="L1V17_000324"
     CDS             complement(34146..34673)
                     /locus_tag="L1V17_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBN1235118.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(34693..35640)
                     /locus_tag="L1V17_000325"
     CDS             complement(34693..35640)
                     /locus_tag="L1V17_000325"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBN1235119.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(35652..37538)
                     /locus_tag="L1V17_000326"
     CDS             complement(35652..37538)
                     /locus_tag="L1V17_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBN1235120.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            complement(37698..39776)
                     /locus_tag="L1V17_000327"
     CDS             complement(37698..39776)
                     /locus_tag="L1V17_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBN1235121.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(39789..40064)
                     /locus_tag="L1V17_000328"
     CDS             complement(39789..40064)
                     /locus_tag="L1V17_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235122.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(40426..40881)
                     /locus_tag="L1V17_000329"
     CDS             complement(40426..40881)
                     /locus_tag="L1V17_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235123.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(41035..42243)
                     /locus_tag="L1V17_000330"
     CDS             complement(41035..42243)
                     /locus_tag="L1V17_000330"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBN1235124.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(42355..42687)
                     /locus_tag="L1V17_000331"
     CDS             complement(42355..42687)
                     /locus_tag="L1V17_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBN1235125.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            42835..43710
                     /locus_tag="L1V17_000332"
     CDS             42835..43710
                     /locus_tag="L1V17_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBN1235126.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(43792..44373)
                     /locus_tag="L1V17_000333"
     CDS             complement(43792..44373)
                     /locus_tag="L1V17_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HBN1235127.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(44379..45638)
                     /locus_tag="L1V17_000334"
     CDS             complement(44379..45638)
                     /locus_tag="L1V17_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBN1235128.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(45640..46686)
                     /locus_tag="L1V17_000335"
     CDS             complement(45640..46686)
                     /locus_tag="L1V17_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235129.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(46921..47196)
                     /locus_tag="L1V17_000336"
     CDS             complement(46921..47196)
                     /locus_tag="L1V17_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBN1235130.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(47439..48749)
                     /gene="der"
                     /locus_tag="L1V17_000337"
     CDS             complement(47439..48749)
                     /gene="der"
                     /locus_tag="L1V17_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBN1235131.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(48931..50160)
                     /gene="rpsA"
                     /locus_tag="L1V17_000338"
     CDS             complement(48931..50160)
                     /gene="rpsA"
                     /locus_tag="L1V17_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HBN1235132.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(50295..50975)
                     /locus_tag="L1V17_000339"
     CDS             complement(50295..50975)
                     /locus_tag="L1V17_000339"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBN1235133.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(51024..51659)
                     /locus_tag="L1V17_000340"
     CDS             complement(51024..51659)
                     /locus_tag="L1V17_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBN1235134.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(51725..53128)
                     /locus_tag="L1V17_000341"
     CDS             complement(51725..53128)
                     /locus_tag="L1V17_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HBN1235135.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWGTILLNLFKKNMEH"
     gene            complement(53115..54146)
                     /locus_tag="L1V17_000342"
     CDS             complement(53115..54146)
                     /locus_tag="L1V17_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1235136.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            54177..54398
                     /locus_tag="L1V17_000343"
     CDS             54177..54398
                     /locus_tag="L1V17_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBN1235137.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(54563..55300)
                     /locus_tag="L1V17_000344"
     CDS             complement(54563..55300)
                     /locus_tag="L1V17_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HBN1235138.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(55453..56793)
                     /locus_tag="L1V17_000345"
     CDS             complement(55453..56793)
                     /locus_tag="L1V17_000345"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBN1235139.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(57030..58553)
                     /locus_tag="L1V17_000346"
     CDS             complement(57030..58553)
                     /locus_tag="L1V17_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBN1235140.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
BASE COUNT        16112 a        12373 c        10011 g        20293 t
ORIGIN      
        1 aaactatttt tgcaaacgat ctgcgaaaat agtttgtttt tttattttgc cattattttc
       61 ttacttattg ggagaaaaaa ttcgcttaaa ctcaaaaaaa tttgaggata cgatataaac
      121 tttcggatag agtataaaat aaggaaacgc cgcagcgttt cctttccaac tgtagccgaa
      181 tataaatttg tatatcactt atttaaaata gctattttct cccaaagagt ttccttgatc
      241 atcgatcaat ccttgtaatg agcgttctaa gataccatgg ctttttttcg attttttttc
      301 ttctgactgc tttgtttcct ctaacgtttt tgttcgattg aatgttcgta cagacggctc
      361 accatttctt ttttcttgat acggcgtcgg ttctgtatcg aacaacagat aagagtcatc
      421 cgtttttttc atcgattcga ttaaatgatc ctcagaaatt ttgctttctc tagggtctgg
      481 gataatcgat gcgggtacat atttaggaac aaaataagaa cgctcccgca ccttcgtgtc
      541 aacagatgcg tttcgtgtag tatgcttgga ctctgtcctt gtttcacttt gtctgacaga
      601 acgagaggaa tcaccaaaaa gtttttttcg tcctgtcgat gtgatttctg attggtaatg
      661 gccggtataa tccggtaatt ttcctttatg cttttccaaa ttttccttac gcggagctga
      721 cttcaatcca tttgttgcac gacgcttgcg acggattttc tcggtgttcg tgttcgtgaa
      781 atgaaattct ttcatctgtt caaacgggga ctgattctgt tcagtcaaaa gatcttcttg
      841 tccgtcaaat aatactcgct tcttgtcgtt ggttaatttt acgcctaact catcatcgta
      901 cgcaggaaaa cggaaatgtt ttcgtctgat ttctttcatt caaaccatcc ttctcaaaaa
      961 tggaactttt ctcaataata gcacagattc attgttttca gtagcaatgc gctgattatt
     1021 ttaagaaaat agcgatgaat ttcataaata tatatatagt aataagactt aattcgttgt
     1081 ctctctgata actagttcag gaaaaaaacg acgataacct tgactcgccc ctttttcttc
     1141 tatttttttt aacaacattt ctccacatac ttcacccata cgtataatat cttgcttgat
     1201 cgttgtcaat ttaggtgaac tgatttggtc taaaaatacc ccatcaaatc caatcacacc
     1261 aaattcttcg ggcaagtgtc ctccagcatt tataatccct cttactgctc ctagtgctag
     1321 ccgatctgaa ctacatacaa aacaagtttt atctgtaaaa tctgcccagt tttctgtcat
     1381 atatctttct acttctgtcg aatgatttgg aaaccgcaag attttactag gaagatcaac
     1441 ttccttcatc acagataaat aaccagtttc ccttgaaatt tcaaaaggct cgtccacttc
     1501 gataccgata taaataatcg tttgataatc tctttctaag gcatattgcg ttgcttttgc
     1561 tgtaccatat tcattatcgc tgtctacata atcatatcct tcagaatttt ccccaaacaa
     1621 gacaactggt ttttccaaac ggtcgatcca atcgaagtct ttttttctga cacctgtgat
     1681 gatgtatcca tcacaagaac cgacgtcgaa ggcatcattt gtaactaatt ggagagaata
     1741 atgcgcttta ccgatccgtt tagcgattcc catcagcaaa ttcatgtaat agggctcagt
     1801 tgtgtcgatt tcttccagta taaataattt gatgatctgc gaccgattcg tgacaagtgc
     1861 ttttgcagca atatttggac ggtaatccag ttcagccatt gctgagaaaa ctaactcttt
     1921 caattcgtca gtcacctgtt ccggatgatt gatgactcga gagaccgtca tttttgaaac
     1981 attggcacgt tttgcaacat ctgctaaagt gggcatgctc tcttcctttc taacatgttg
     2041 tcattcttac tatcaattat accaaatttt cctaacagag tttattatag cccaaaataa
     2101 aaaacggaaa atcctctatc gtcatgagtg attttccgtt tcaattattt atactttttt
     2161 atcaaatttt ttgctaaaaa agtggaagct tcttccatta gttgtatttg taccatatgt
     2221 cgctgtgttt ttgaggaacg aaaaacaatt tcttttccgt aagacttatg ccgatttttt
     2281 tctacaaatc gttccgtttg tatataaggg attttttcgt cagcttgtcc atgccaaaag
     2341 aacagaggac gtccagctaa cttttccggc tgcaatgaca aatcatagct cttaacccat
     2401 gaaatcaaat caaaatagtc ttttggtacg acataattat attccgatgc gcgccttacg
     2461 atttcttttc catattccaa aggtgcaggg gaacccatca aacacacgcc cgctactata
     2521 tgaggatgtt tagccaacaa ggcgcatgtt gtcattcccc ccatcgaaac cccgccaact
     2581 gcaagctgat catgtagaag acctcttttt tctaaatgct tgataagtgt gtcaaattca
     2641 aacagatttc cgtagatact atcccaaaat gtataggatg gaatagaaga aaccggctgt
     2701 ttgcgctccc catgattcat cgcatctggc aggatcacac gaatgccctg ctgcgcaatt
     2761 tttcttcctt gcgtcaaaac taactcctta cttgtctgcc atccgtgata atagatgaca
     2821 acgggaatac gttcctctct taattctttc agaacaactt ctaacactgg aatatgatgg
     2881 acagaacgtt tcaatataat tggattcaat tgttactcac ctattttcat taaatttcct
     2941 gatcgccata gcaaccatgc tccaacagtt gtctggaaca ggttcagtgt accaaataat
     3001 ataaatgcag gactgaatgg ctcgggaaat aagcacagag aacaaagtcc caccactcct
     3061 aatgctagcg aaaggagtgg ataaatagaa aaattcaaaa aactggcaac gctaccgaaa
     3121 atattaccaa taaacagtat caaaaagaaa aaaacgctta aaattaaacc atctgtcagc
     3181 gacatctgaa aaacaatgtt ctctacctca attggctgtt gaatcgaata gacacctaag
     3241 tatatactga gaaggagact tagcacgtgg ctggcacaaa acacacgatt gaccgttttc
     3301 attttaatca cctaacctat ctttataatt ctattataat cattttatca tttttttgta
     3361 tgtataaagt ttcaattttt cttcacttac gatttttttt gatattgttg ttatataaat
     3421 gaaaggagtt ttacaaatga ttgatccaaa aatgttgggg atgatcttcc tcattaattt
     3481 tgcttatatc actctgaaca cgttacgttt catgttgaca atgaaaggct atcgactgat
     3541 tgctccactt gtcagtatgg tcgagatcac gatttatatc gtcggcttat cccttgtttt
     3601 agatcgttta gataatccac tgaatttatt tgtctatgcg ttaggttacg cagtaggtat
     3661 cagtgtcgga attttgattg aagacaaatt ggcattagga tacatcatgg tcacaacgat
     3721 tttgccagca aatagcgcag aagataaaag tttgccgggt atactgagag aacacggtta
     3781 tggtgtgaca cagacttctg caatggggct ggaaggtgag cggctagttc tcgaaatact
     3841 ttctcctaga aaaagcgaac gtgaactgta tcgcctgatc aaagaaatcg aagagcgtgc
     3901 ttttatcatt tcttatgagc caaaatatat ttcaggtggt ttctggacta aaaaagtgag
     3961 aaaacgacaa ggaaaataac tcacaaactt aaaaactgtc taatatctaa attaaatttt
     4021 aaatgttaga cagtttttat ttattatttt gattaaaaaa catcgacata tactcatcaa
     4081 tttgttatta tactttatat acttatcaat ttaatttgga gatattatgg aaattcaacg
     4141 tagaaccact aattttttac atttaggctc tttttttgca actttgacga tcttattttt
     4201 tctatgttat tcatacctta agacctcaca tgcgccttct agtgcattag gctggttgct
     4261 tttggatcat tctgatatca cagaagccga agaaaatccg ttttttttga ttttgtcttc
     4321 tctttgcggc ttactgtttt ctgtttattt cggtgcctat ttttttcatc gacatcctgg
     4381 tacgttaaac gaagcttcaa gcgtattgat tgcatttaaa acgttttctt ttttagcaat
     4441 tcttttttat tcgtttaatc acaatacgct tttcttcttt atcatgaatg gtttagtcgt
     4501 gattttatcc atttttactt attttatttt ttcactcatt tttagccaat tgaaatgtcc
     4561 gctcttcttt cgattagttc ctgtcacctg ttttatttac agcttgtttt ccttttttgt
     4621 ccttgcttta atgccactga ccaacccttc gacgatccaa gtcgcaggaa atctgttgga
     4681 tatgctcttc atcgtcagtc taggtgtatt tatgtggcaa agaaaaaaca aacaaaataa
     4741 aaagcatttt gaagcctgac tattacgact tcataaatgc ttttttagtt ttaaacactt
     4801 caatctaaaa gaataaccca agattggata aattattaat gactcgccat tcgtttctta
     4861 gtgattctgg attatcaaat ggacttccta atctaatcag ctagttcttc ccataaaatg
     4921 ccatacttga ctgaatcata atattgatta tttaaaaatc taacttttct tatcactact
     4981 tcctttgtca ttccacattt ctcaccattt ttttgcattc ctttgtttcc agaccatgta
     5041 gtgaatctaa taggtggtag ataggcaaaa tactcaaata attcttttaa ccataaagga
     5101 agagaaaggc tcctcctgca agagtcagta taatttttgc ttactgctct cttaggtttt
     5161 actcactaaa actgttccat attctttgat ataagaaaat gcatgcggta taaatttctt
     5221 gctcagctca gaaaagattt gtcgtttaag aaaggccatt tcctccattg tcaatgaagg
     5281 atccaatgtt ggtaattcaa tctcaaaatt gtttttttcg acaataggta attctaatgt
     5341 gaatgattct tcttccttta tagtattcgt cacaagtaga gactgatgga aaatactagg
     5401 ccggcgattt ttatatttat tcttacgtat cctgtcaacg ataacttcta tttgatcaaa
     5461 aaagtacgat tcatttacgt ctccaataag ttcggctaat tctttgaatg ccttcgttac
     5521 aggaagctga ttcttctgta caaaaaagta attagccaaa gtaagcggga agtgttctat
     5581 agaggaaagt gtgataaaac ggtacttctc atttcctgca gttgtcctca gcaattctgt
     5641 ctctcggctg tttcttactc cataaaaata cgcttctttc cgttcatctt cgaaacaata
     5701 cgcccaaata acttctccca tcgctaattt ttgttcatca acagagagtc tcttcaattg
     5761 ttcagctatg gtttcagcag ccgaagtggc ttgttgcaag taatctttag gatcaaatat
     5821 tggaaagttc aaatgatatc ttcgttcttc cctcttgatt aatcctgcat cgatcaataa
     5881 atcaagaaaa tgggaaaatt tattttgcga aaattctttt ttcaattctc ttagaatcgt
     5941 ttcttgttct cgatgttcat atagataatc ggtcaatgaa gaaaaaagcg gatcatcggt
     6001 cagtttttga taaaagtttt ccttattttt tgaataatag ttcatatatg ttctcttttc
     6061 tatccgtttt attttactta aaaggctttt acgtaaaaag gaggaagaac aagagtcata
     6121 attgactgtt attctcctcc atttcttcgg cctttagtat gttctatgtt tctttttata
     6181 tcaatcgctt atccattcat tttgaatgct tcatactacc atttgattag ctaaatacag
     6241 ccgtcaattg aggtacgact tgttttttac gtgaaacgac acctttaagc aaagcacggt
     6301 tgttggtcaa agttgtttgg aaagcttctt ctactttttc ttttccttta ccagcaacaa
     6361 gtaattctga atcactgtct aagatgtttg tgacaactaa tacgaacaga tcgtagccat
     6421 ttgctttcat ttcatcttcc attgctgctt ctagctctgc ttgtcgatcc atcacttcat
     6481 taaggtccac tgtattgact tgagcgatac gaacgttgga actgcccatt gggaaacttt
     6541 ttgcatccaa atcaagaaga accgcagctg atttatcact tagatttgtt cctgctttca
     6601 acatttcaag tccataagtg tttagatcga cttcagcgat tgctgcaagt tcttttgcag
     6661 ctgcttcatc ttcaggcgta catgttggtg atttgaacaa caatgtatct gaaatgatag
     6721 ctgagagcat gattcctgcg atttctttag gaattgttac ttggttttct ttatatagtt
     6781 ttaaaataat cgtacttgta catccaactg gttctgcacg atagtacaat ggattagctg
     6841 tttcaaagtt tgcaatacga tggtggtcta ctacagctaa aatatttact tcgctgatat
     6901 ctgaaatact ttgttggaat tcattatgat ccacaagcat gacatctgca ttttctgctt
     6961 tagctgactc tactactcgt ggtgcagata gctgaaagtg gtctaatgcg tattgtgttt
     7021 cttcattagg tgtacctaga gcaactgctt ctgtttcttt acctaattca ttttgcaagt
     7081 gtgaaaacgc aatggctgcc ccgattgcat ctgtatctgg attttggtga ccaaaaacta
     7141 aaatttttga catgtcattc gctcctttgt gatttctcct atttaataat agcaaaaaaa
     7201 cggaaagaag caatacttat cttctttccg atgcgaccta tcgcgttaaa tattttgtat
     7261 actcttctgt atgaagcaat cgtttagcat tttcgacacg ttcttttgta ggtggttcga
     7321 tcccttctaa tggatatttc aaaccaagtg tttcccactt gtattttccc atcgtatgat
     7381 aaggaagaat ctctactctg tctacatttg acaaggtttg aataaagttg tctagtcgga
     7441 tcaaatattc atcataatca cttcgctcag gaactagtac atggcgaatc caaaccggtt
     7501 tgttgatttt tgacaaatat tgagccattt ctaaaatatt ttcattgtcc caatgcgtta
     7561 gttttttatg ctcttcatta tcgatgtgtt tgatgtcaaa taacagtaaa tctgtatact
     7621 tcatcaattc ttgaaaacgt gaaaagaaag gttcttcata cgtaaaaggt tttccgcatg
     7681 tatccaatgt agtatgcatc ttccgctctt ttgctttttt aaatagttcg atcaaaaaat
     7741 cgatctgcaa tagaggttct ccaccactaa cagtaatacc acctttatct ccccagtaag
     7801 gtctgaagcg ttctgcttta tctaaaagtt catctgctgt gtattctttc cctccgccaa
     7861 tattccaagt atctggattg tgacaaaatt ggcaacgcat gcggcatcct tgcataaaca
     7921 cgacaaagcg cagtccaggt ccgtctactg aaccgaaagt ttcgatagaa tgaacatagc
     7981 cgattgtttt ttcttccatt taagttcaca tcttttcttt gatttcattt taagtacaag
     8041 ttagctgtcg aagcgaagct ttctgaacaa aatttttcgc aattgccgct tcgttatgtg
     8101 taaaatttac agggacggaa catacaagtc ctgcccctgt aaatcgtttc tttcaaataa
     8161 gcatactgat tattcgattt tgatgcgatg gctattcaac gtcctttcga cgctaagtcg
     8221 aaaaactttt ttcacgaact ttttacattc tgtcgtgtga agttctcatc aagacatcta
     8281 attgttgttc tcttgtcaag tcacggaatt taactgcata accagatacc cggatcgtca
     8341 agttcggata tttcattgga ttttccattg catcacgcaa taaatcatta ctgaatacat
     8401 tgacattcaa atgataagct ccttttgaga agtatccatc taagacatta cgcaagtttt
     8461 cgattcttgt atcttgttct tttccaagac ctgaaggatt gattgtttgg gtatttgaaa
     8521 ttccatccaa tgcacagccg taattcattt tagctgttga gttcaggcta gctaataacc
     8581 cactttgttc cgcattgtaa cttggatttg ctcctggcgc aagtggtttt ccagcttcac
     8641 ggccatcagg agtatttcct gtatttttac cgtaaacaac atttgaagta atcgtcaata
     8701 atgaagttgt tggttttgag ttgcggtaag ttttatgacg tttgatttgt cccatgaagt
     8761 attccaagat ccatgaaact aattcatctg cacggtcatc atcatttccg tatttaggga
     8821 agtcgccatc cacttcaaaa tcaactgcta ttcctttttc attacggatt gcttttactt
     8881 ttgcatattt gatcgctgac aagctgtctg ccgcatgaga gatcccagca atacctgtag
     8941 caaatgtgcg ttgcaagtca gaatccatca aagccagctg agctgcttca taagaatatt
     9001 tatcatgcat ataatgaatg atgttcaacg tattgacata tagttctgct aaccaatcca
     9061 tcatattcat gaagttatgt ttcacttctt caaagtctag tatttctgat gtgattggac
     9121 gatattctgg tccaacttgg gcgccagtca cttcatcgac tccgccattg atggcatata
     9181 atagtgtttt agccaagtta gcacgagcgc caaagaattg catgtctttt ccgacaactg
     9241 ttcctgatac acagcaagca atcgcacaat catcagaacc ccattgttca cgaagctgat
     9301 tatcattttc gaattgaatc gaagaacttt cgatagcgat tctgctagca tatgttctga
     9361 atccttctgg aaggtgttca gaatacaaaa cagtcaagtt tggttctggt gaaggtccca
     9421 tatttgttaa tgtatgaagc agacggaaat cattctttgt aactaatgaa cgaccatcta
     9481 atcccatacc tgcaatggat aaagtagccc agatagggaa tcctgagaat aattggttat
     9541 attcaggtgt acgcgcgaat ttgaccatac gtaatttcat tactaagtgg tcgatcaatt
     9601 cttgtgcttc tttttctgtg attactccat tatccaaatc acgttggata tagatatcaa
     9661 ggaatgctga gatacgtccg attgacatcg cagcaccatt ttgtgatttg attgctgcta
     9721 aatatccgaa gtatagccat tggacagctt cttttgcatt tgcagctggt ttagaaatat
     9781 catagccata tttcgcagcc atttctttca tttgcgctaa tgcacgatat tgttcagtga
     9841 tttcttcacg taaacgaatc acttcttcac tcattgtatg ataaccagtc atatcatgat
     9901 cttttttctt ttgttccatc aaatagtcga ttccatacaa tgccacacga cgatagtcac
     9961 cgatgatacg tccgcgaccg taagcgtctg gaagccctgt aatgattttg tttttacgag
    10021 cagcacgcat ttcagcagta taagcgtcaa atacaccttg attatgtgtt ttgcgccagt
    10081 cagtgaaaat atgtgtcaat tcatcgtttg gtgtatagcc attgcttttt agcgcattgt
    10141 tagccatatt gattccgccg aacggcatga atgcttgttt caaaggtttg tctgtctgta
    10201 gaccgacgat tttttccaaa tctttatcca aatagcctgc atcgtgtgaa gtaatagttg
    10261 atacgatttc tgtgtccata tcatagacac cgttacgctc gaattggata tcatttaact
    10321 tttgcaattc atcccataat ttttctgttg cttctgttgg gccttccaaa aagctgtcat
    10381 caccgcgata ttcagtgtag ttattttgaa taaagtctct agtgtctacg ccttctttcc
    10441 atttggtacc tttaaatcca ttccattgct ccattgtatg gacctcctaa atttctgttt
    10501 tatgtaacag tttttacgtg attagtataa cacagcaccc tatctttgca agggttttct
    10561 tgttttttat ttaacaattt ttatgtttta tttacatata tttaaatcaa cgttgacata
    10621 ccaacattta agcattgtga acactttcat ctttttttgc aaacgtataa ggatttatta
    10681 aaaatgaatg aaaaagagac gccacctgta ttaatacaga tggcgtctct tcattaaaat
    10741 actacaacag ttacgactcg atgaaaatct caggagcatc gataacttcg atgacttctc
    10801 cacctttttt ctcatccatc gcaaatgatc cattcgatgt tcgatcacct atagggaaat
    10861 cagttgggtc aatcgttaac tgctgccctt tttgattcat caaggttatt tcttttgatc
    10921 ttccttccga catatagata atacggtgcg gatttttttt cagctcacgc atgaccgtca
    10981 ctccccgctt cgcacgtgaa gtttggctga tttcttgagc aagcatgcgt ttaacagctc
    11041 ctcgctgagt aacgattacg atcggcgtat caccttctgc taacacaagc agcccgttga
    11101 taatcctatc tccatctttc aaattcatag acttcactcc agctgccttt gctccaacaa
    11161 cgggaacatc tgttaaagga tagcgcaaac ccattccttg atgcgttact aagaaaacat
    11221 ctaagcctgg ctgatcttct ttcagataca cagcaatcag ttcatcttct tccgccttta
    11281 gcttcataca gctgagcgga cggctcttat aggtgcgcca tggttcgaac tctgtcattc
    11341 gtgtttgctt gatcaatcca ttcttgctga tgaatacaaa tgttttctct gcttgaattt
    11401 tttgatatgg gaaaacagct aaaatcgatt cgtctacaga cagattggag attgtttgag
    11461 aaatgtgctc accagcatct ttccatttca aatcgggtag ttcatggaca gggcggtaga
    11521 tcacatttgc tttatttgtg atcagaagaa catggtccaa tgtactcaat tcacctgagt
    11581 atagcaagta gtcgccttct cgcatcccga tttcttctgg tttggaagca ctataagaac
    11641 gaaggcttgt tcgcttcaca tagccttctc gcgtcacact gacaattacg tcttcttgtg
    11701 ccactaagac ttgcgtatca attttgattt cttcgatttc gtcttcgatt gtcgttagac
    11761 gagcggaaga ataatttttt ttcacttctc gcaattcttt tttcataaca gagaaaagct
    11821 ctttgtcatt tgaaaggatt ttattcaact ctgtgatttg cgcaatcaag ctttcggatt
    11881 ccttttgaag ctctgtgata tccgtgttcg tcaaacggta taattgcaat gtgacaattg
    11941 cttctgcttg ttcttctgta aattgaaaga cgtcgactaa attctttttg gcgtcttttt
    12001 tgtctttact ttcacgaatc gttgcgatta cttcatccag aatcgataaa gctttcatca
    12061 atccttctac gatatgctgt cttttttgag ctttggctaa atcgaattga ctacgttttg
    12121 ttatgacttg ctttcgatgc tcgatataac ttcttaaaat gtctttcagt ccaacttgat
    12181 gcggagtcat atggtcgata gcgaccatat tgaaattgta attgatctgt agctcagtgt
    12241 ttttgaacaa ataattcaaa attccttgag cattggcgtc ttttttcaat tcgacgacaa
    12301 tttgcagacc tgttctatca ctttcatctc gtacttcagc tattccatcg attttcttat
    12361 tcaaacggat ctcatccatt tttttcacca aggtcgcttt atttacttca tatgggattt
    12421 ctgtgatcac gatttgctgt ttattaccct tcattgcctc tatctttgtt ttcgaacgaa
    12481 gaataacttt tcctcgtcct gtttcataag cttttttgat ttcatctttt ccttgcaaga
    12541 tccctcctgt tggaaagtca ggtccaggaa tatattccat caatttttca aggctcgctt
    12601 gtggatgatc gatcatatag attgtgccat cgatcacttc agctaagtta tgagtcggga
    12661 tttctgttgc atatccagca gatatacctg tcgatccatt gacgagaagg tttgggtatc
    12721 gagctggaag gactgttggt tctttttctg tatcatcaaa attccacacg agatcgactg
    12781 tttctttctc gatatctgct agcatctctc cacttaactt ggataatctg gcttcagtat
    12841 aacgcatcgc agcaggtgga tcaccgtcca tactcccgtt attcccgtgc atttcgatca
    12901 gtacttcccg caacttccag tcttggctca tgcggaccat cgcttcataa atactgatgt
    12961 caccatgagg atgataattc cccatgatat ttccgacaga ttttgctgat ttacggaatc
    13021 ctttgtcata cgtattgcca tctttgttca tggcaaataa tatccggcgt tgcactggct
    13081 tcaatccatc acggatatca ggcagtgcac gttcttggat aatatatttg gaataacgtc
    13141 cgaagcggtc acccatcact tcttctaaag ttaattcttg tacttcttgt cgattttcca
    13201 tcaggtgacc tcctattcta cttcaaataa ctgattgttt tcatttttat ctgctcgttc
    13261 ttcatctaat aaatcattag aaactgaagg agagatttca gtatcctctt ttttatctaa
    13321 gatactgcca tcttcttcga gcgtaaattg cacgtgattt tcgatccatt ttcttcgagg
    13381 ttctactttg tcacccatca gtgtggttac tcgacgttca gcttgcgcag catcatcgat
    13441 acggacgcgg atcaacgtac gggaagtcgg atccatcgtt gtttcccaca attgttccgc
    13501 attcatctct ccaagtcctt tatatcgctg cagcatatat cctttgccga cttttttaat
    13561 cattgctgcc aattcgtcat ctgtccacgc atattcaatg acttgcttct ttccttgtcc
    13621 tttggatact ttatataaag gcggtaacgc gatatatact ttcccagctt caatcagcgg
    13681 tttcatataa cgataaaaga aagtaagcag taatacttga atatgggcgc cgtctgtatc
    13741 cgcatcggtc atgatgatta ctttgtcgta attacagtct tcgatagaaa actcaggacc
    13801 gactcctgca ccaatcgtat agatcatcgt attgatttct tcatttttca agatatcttg
    13861 cattttagct ttttcggtat tgatgacttt tcctcgtaaa ggtagaattg cttggaactt
    13921 tctgtctctt ccttgtttag cagatccgcc agcagaatcc ccttcgacta aatacaattc
    13981 atttttctta gggtttcggg attgtgcggg tgtcaatttt cctgaaagaa gagattcgcc
    14041 ttttttacgc ttcttcccat ttcggctttc ttctctggct ttacgtgctg cttctctcgc
    14101 ttctctggct ttgattgctt tacggaccaa catctggctc atttcgctat tttcctgcaa
    14161 ataaaagccc atttgttcac tgatgacgtt atctactacg gtacgagcaa ctggcgtacc
    14221 aagtttttct tttgtttgcc cttcaaattg cagaagattt tcaggtacac ggatagaaag
    14281 tacagcagct aacccttctc tgaaatcact accttccaga ttcttgtccc gttctttcag
    14341 caaaccaact tttctcgcat attcattata agatttcgtc atcgccgctt tcataccagc
    14401 ttcatgggtt cccccatctt ttgtccgaac gttattgaca aaagataaaa cattttctga
    14461 ataaccgtca ttgtattgat aagcgacctc tacttcgata ccttcttttt ctcctgaaaa
    14521 ataaacaact ggtgtcaatg tatctttttc ttcattcaga taatcaacaa attctttgat
    14581 tccttcttcg taatgaaaaa tttccttgac tggttcttct ccacgaagat cagaaagaga
    14641 gattttaacg ccttttagaa gaaaggcaga ttctcttaac cgttcggcta aaatttcata
    14701 tgaaaatttc gttgtactga atattgtatc atctggtaaa aaatggacag tcgtcccgtt
    14761 tgcttttttt gtttttccta tctttttcaa agtaccgtca ggtttaccgc cgtttttaaa
    14821 tttctgctga tactctacgc catctctaac gatcgttaca attagccatt tcgataaggc
    14881 atttaccaca ctggctccta caccgtgcag tccaccagaa gttttgtacc ctccttgacc
    14941 aaactttccg ccagcatgca gcacagtaaa aatcacttca actgttggta ttccggaagc
    15001 atgcattcct acaggcatcc cacgtccgct atctgcaaca gttatactat tgtcttcatg
    15061 gatggtcaca tcaatctcac tgccataacc tgataatgct tcgtcaactg cattatcgac
    15121 gatttcatag actaaatgat gcaagcctcg gctgtcagtg gatccaatgt acatccctgg
    15181 tctttttcta actgcctcta atccttccaa tacttggatg gacgagtcat tgtattcgtt
    15241 gtttactttt tttgccaagg caaacgctcc ttcaataata ctttgcggca aaaccgcacc
    15301 acgattatca tactagaaaa ggtcgtgaaa aaaaagaggg tagacgagaa atcaatttta
    15361 attatctcct aaccgctttt tcgacattcc cctctatcga tcatctcttc tttgtggtca
    15421 tttttatttt tggttttctt tcaacttacc aagttcaatc ttaatacaac gatccattac
    15481 gatatctgta cgtcctgctt ttcttagcat ctcagctgct tctttgtttt caatccctaa
    15541 ttgtgcccag aacactttag catcagtttt caaaaaatca cctgctattt caggtaaaaa
    15601 ttcactccgt ctaaatacat ctacgatatc gattggatca tcgatttctg tcaaattcgc
    15661 atagactttc tcgcctagaa tttcttcacc agccaataat ggatttactg gtatgatttt
    15721 atatccattg tcttgcaata cctgtgcaac catgtaactt gttcgttctg gtttattgct
    15781 caagcctacg acggcaatat tttttgcttc ttccaaatag ttgaaaatcg tttcttgtgt
    15841 tggatttttt acagacattt ctgccacccc ttgcttttct ttttattcca tctattatac
    15901 ttgtatcttt cattttttca attgttcctg ttacctattc atgctaaaat aaaggatagt
    15961 tttcaacttg aaagagggta aaaaatgaaa ttgatcttat tacttatttt agcatatctt
    16021 ttaggttcta ttccttccgg tgtctggatt ggcaaattgt ttttcaaaaa agatatccga
    16081 caacacggga gcggtaatac tggaacgacc aatacatttc gtgtattagg caaaacagcc
    16141 gggattgttg tcctgcttat ggatatttta aaaggtacat tggctacttg tttgccgatg
    16201 atcttccacc tttctgggat taaccctctt tggtttgggg tatgcgccat tcttggccat
    16261 acatttccga tttttgctgg gttcaaagga ggaaaagctg ttgcgacaag tgcaggaatg
    16321 cttttaggat ttaatcctgt attttttgtt tattcttgta tcatctttat cgttagttta
    16381 ttttgtacaa gtatggtgag tttgagcagt atgatcagtg cagtattgat cactttatct
    16441 acgatcgtcc ttccttatgt agctcctgtg attttggcta agcccaattg gttactgacg
    16501 atcattgcct ttttagtttc ttcctttatc ttttatcggc ataaagacaa tatcaagcgt
    16561 atcagaaacc atactgaaag tcgaatcccg tttggtttga atagcagcaa gaaaaaatcc
    16621 tgatactttt tcattccaaa gagataaaac gggagtgtga caaatcgatg tcacactccc
    16681 ttattactta caggatagct tttttacaca ccttggtaaa cggtgttccc tgctaacttc
    16741 tcggtcacaa cctcttactt cactgtgatg gaatattttg tcttgaagat ttcatgggca
    16801 cctagttgat tgatccctac tttttccatc aagtttccac tactgttcac cgtgtcagcg
    16861 attccgcacc acggttcgat acaaacgaaa ggcgcttctt ttggataagg agaccagatc
    16921 cctacataag gcatatcttt atagcttaaa gttacgctat gggaagattt ttcacttcga
    16981 atggcgtacg catttagacc ccttgtttca aaaaccaagg catcttgctc aaaaagttca
    17041 cgattcaaag ccagattcgt atttgtctga cctaacgtct tttgatccat atcgatgaat
    17101 gggcctttca atggtaggcg taatcttgat ttcaatggag aaaatgccag atagaaatct
    17161 tcaaatgaca atccttcttc aagaggtaca ttgaaagcag gatgtccacc gatagaaaag
    17221 aacatttctt tttcaccggt atttgccact tgataatgaa ccgtgatgcc gtctcctcct
    17281 aattcatagc tgatcactaa ttcaaaatca aatggatact tttctaatgt ctccggcgta
    17341 ctccttaaga tgaaactagc catttcttgt ccatgttcaa tgacttcaaa atccatatcc
    17401 cgagcaaatc cgtgttgccc catttgatat gttttccctt gataaacata ctgatcatct
    17461 tttaaacgtc caacaaaagg gaataaaacc ggtgcatgtc tgccccaata cgctggatca
    17521 ccttgccaga tatactctaa accatgttct tttgatttca gactgatcaa ttccgcaccg
    17581 tgttcagcga tttcggcgat cagctggtca ttttgaataa taacagtcat tgccattcct
    17641 ccaacttcga cttacttttt aaaatgggaa ggctggaaca aacatttcta tctgccccag
    17701 tccccttact tctaataact gtgttttgct aactcgtctt taaaacggga attcaatact
    17761 tttaaataag ttcccttcat gcctaacgaa cgagattcaa tgattccagc tgattccaat
    17821 tttcgtaaag cattgacgat cacagaacga gtgatgccga tactatcggc aatattagaa
    17881 gcagtcagac gaccttcatc tccatccaat gcttcaaaga tagcttgtac agccttcaat
    17941 tcgctataag ataatgtgtt gattgccatt tggacagccg ttgcactccg tacatctgct
    18001 tcgatgcttc gagacttctg ataaaggatc tgcataccga caaccgtagc tccatattct
    18061 gctaagacta gatcgtcatc tgcaaacgat tgttccatac gagataagat aatcgtaccc
    18121 aaacgttcgc cagctccaaa gatcggaacg acagtcgtca gaccaaatgg atatttctct
    18181 cttgactcta ccggaaatgc agtaatatca ctagtaattg ggatattagc ttcagttttc
    18241 atcaactgtg ccactgtatc agtataagat tcaggaaatt gtttctcaac aaacattgtt
    18301 ttgattcgtt cattgttcac atcgtgacgt tcattataac ctagtaatac tccgtcactt
    18361 cctatgatat aggtgttgct gtcaagaata ccacctagtg tgacagccat tttatcgtaa
    18421 ggcaaatctg cttgcatgtc aaaagtattc ttttgctgca aaagtgtgtt tatcttgcgg
    18481 gttttcgtta gcaagtctgt cattgtcgtc ctccgatttt ttataaaata tagcgactta
    18541 aatcttcatt tgccgcaatt gagccaagtt tgtcatccac atatgcttct gtgatcgtta
    18601 tttctcccat ttgcatatct ggtgcttcaa ataatagatc ttctagtagt ttttccaaaa
    18661 tggtatgcag tctgcgtgcg ccgatattat ctgtgtcacg gttgacatcg aaagcgattt
    18721 gagcgatccg ttcaattgct tcttttgtaa acgtaactga cacattttct gtaccgatca
    18781 acgcgacgta ttgttttact aaagcattat ttggttcggt cagaatcttc acaaaatctt
    18841 cagctgtcaa atcatctaat tctacccgta tcgggaagcg tccttgaagt tctggaatta
    18901 gatcacttgg tttagacaaa tggaaagctc ctgaagcaat gaataggacg tgatctgttt
    18961 ggatgatccc gtattttgtg tttacttgtg aaccttcgac aattggcaat atgtctcttt
    19021 ggacgccttc tctggatact tctccagatt gctgtgattt agaagtgatc ttatcgattt
    19081 catcgataaa aataattcca ctttcttccg ctaatttgat tgcctcacta tggatatcag
    19141 catccttgac taattttgct gattcttcct tgatcaataa ctctaaagct tctttgactg
    19201 ttaccgtccg ttccactttt ttcttcggtg tcaaagcacc tagagtttca tttaggtcga
    19261 tccccatttg ctccaatcca ttgttcatca ttggtgcagg tttcttttgg tcttcaactt
    19321 caatggttac ttcacgacta tccagtaaac ccttttgtag ttgttccaag actgtacggc
    19381 gattgattcg aatatcttct gtcacttctt cttgcggttc agcggtattt tgctgactag
    19441 cattaaaaag attcatcatt tgttcaaatt gattagtgga ttgtttctgt tcttttttga
    19501 taccaggtac caagattttt accaaacgtt tttctgcatt ttttttagca cttgtgtata
    19561 cacggctgta ctgctctttt tctacgattt ggatcgcatt ttctactaaa tcccgaacca
    19621 ttgattctac atctcttccg acataaccga cttcagtaaa ttttgttgct tcgactttga
    19681 caaatggtgc attgacgatt tttgccaaac gtcgtgcgat ttctgtttta ccgacccctg
    19741 taggtccgat catcagcata ttttttggtg taatatcttg ttgcattttt tcatctaact
    19801 gcaaacggcg atagcggtta cgcaaagcaa cggcaacaga tttttttgct gcgtgctgtc
    19861 ctacgatata ttcatctaat tcacttacga tttgtcttgg tgtttgtttt aattcataca
    19921 tatctactca cctcttacag ttcttctacg ataatattat gattagtaaa gatacagata
    19981 tctgcggcaa tatttaacgc attttctgca atttctttcg cactcatgtc gttttgagca
    20041 tagtttttca ttgctcgggc tgcagccaac gcaaaattcc ctcctgatcc gatagctaag
    20101 ataccatcat ctggtgtgat aacttctcct gtacctgaaa caagaagcat ttctttatca
    20161 ttcattacga tcagcatcgc ttcaagtttt tgcatagatt gctgtgtccg ccattcttga
    20221 gctaattcga cagctgcgcg ttgtagattc ccgttatatt cgtttagttt gccttcaaat
    20281 ttttcttcta aagtaaacgc atctgcaaca cttccggcga aacctacaac aacttctcca
    20341 ttgtagatac gtcgtacttt ctttgcagtg cctttcatga caacagattc acccattgtt
    20401 acttggccat ctccagccat agcaaatttc ccgtcttttt cgacggcaca gatagtggtt
    20461 gaatgaaatg gtgattcgac catgtttgtt tcctcctaaa tttgttcttt tccttatttt
    20521 tacgctcttg gatggaaaga acgatagttt ttttgtaaac tttcttttgt tacatgggca
    20581 tagatctggg tagtcgataa attggcatgt cctagcaatt cttggactgt ccgcaaatct
    20641 gccccattat ttaataaatg agtagcaaat gtatggcgca gcatgtgagg atggatatca
    20701 ctatccaaac tgcttttttt gatcatttga ttcaagacat attcaattcc agtaggcgtg
    20761 attggttttc catgatgatt cacaaaaacg atatcatgct cttcgtgata ttttgtcatc
    20821 aatacctggc ggccttccct gaaatattct tgcagagcat cttgagcaaa agaacctaga
    20881 ggagcatatc tctctttgtt ccctttacca tggatcaaca tgacctctga atcaaaatca
    20941 atgtctgata ccgacaaact gctacactca cttaaacgga tgcctgaccc gtaaaggact
    21001 tccagtaaag cgcggttcct caaatccaaa ggactatctc ctgctacgct gtcaaaaagt
    21061 gcttgcattt cattttcata aaaaaaacgt ggcagtctca aatttttctt tttgagatga
    21121 acgtaagaaa atggattttc ttttatcact tcttctttga gaagatactg ataaaacgaa
    21181 cgtaggctgg ctatcttgcg actgatagaa tttctgctat agctaggacg atgatcagct
    21241 aatgcactca aatagacacg aaccgtaaaa tattccgcct tcagcagatc agcgtctcca
    21301 gattcctcca aaaaatgttt gaaatggaga atgtcttctt catatgcttc tttcgttttt
    21361 tctgaatatc ctctttcgac aatcaaataa cgcaaaaatt tttgttccca cgtggcttct
    21421 gtcattttct caccttcctt ttgtcccaga gaataattta gcacagcgtt tataaaaaga
    21481 caaataaatt gtcagaattt aaccaatatt tctaagtttg ttcacaattg gcgcaattcc
    21541 tcacattttg tttgagaaat tcttaagaaa aacgcaagaa aaagagcgag actatccgtc
    21601 tcaccctctt catggagttt ccttactcat ttgggattgc agttttttct aattctgttt
    21661 ttattgcctc attagctttt aaagctcgtt gtgcaattgc ttcatatctt gcttttttgt
    21721 ctcgaatgcg ctctggcagt tcaggaaaca gaccatagtt ggcattcatc ggttggaaat
    21781 gttttccttc cgcatgagta atgtagtaag ccatacttcc aatagctgtt tcttgtggaa
    21841 actcgactgg ttccatttct tttgctaagc gtgcggcgtt gattccagca agtagtccgc
    21901 tcgctgcact ttcaacatag ccttctacac cagtcatctg acctgcaaag aacagatctt
    21961 cgcgtttcgt tgattggtaa gtcggtttca gcaattctgg cgaattcata aagctgtttc
    22021 ggtgcatcac accatagcga acgaattcag cattttctaa cccaggaatc atccggaaaa
    22081 cacgtttttg ctcgccccat ttcaagtgag tctgaaagcc cacgatgttg tataaagaag
    22141 ctgcagcatt gtcttgacgc agctggataa cagcataagg acgtttgcca gttttaggat
    22201 cttccaatcc aactggtttc ataggtccga aaagcatcgt tttgaatcct cgctgtgcca
    22261 ttacttcaat tggcatacat ccttcaaaat atttttcttt ctcaaaagat ttaagttctg
    22321 ccacttcggc attgattagt gcctcatgga aagctttgaa ttcctcttct gtcatcggac
    22381 agttcaagta agctgcttct cctttgtcat agcgggactt caaatatact ttatccatat
    22441 cgatcgtagc tttgtctacg attggtgcag ctgcatcata gaaataaaaa ccatctgaac
    22501 cattgaatgc tttgatgctt tctgctaatg gatgagaagt caaaggtcct gttgctacta
    22561 cggtgattcc ttccggtatt tcagtaattt cttcgtttat cactgttact aatggatgct
    22621 ctttgacttt tcgggtaatt gtttcagaaa aagaatcgcg gtcaacagct aaggcaccac
    22681 cagctggcac tgctgtttca tctgccgaag tgattactac cgaattcaat cggcgcattt
    22741 cttctttcaa taaccctact gcattagcca aactgtttcc tcttaatgaa ttggaacata
    22801 ctagttcagc aaaattactt gtgtgatgcg cctcagtcga tttgactgga cgcatttcat
    22861 ataaacggac agggactcct gcttgtgcga tctgccaagc agcttcactt ccggcaagcc
    22921 ctgctccaac aacatttacc attttcaatg aaagaacctc ttttctatta tttttggatg
    22981 tcttcttcgt aatctccatt tacacagact acttgtttac cgcctttgac tttcttctcg
    23041 accagatatc cgtcacattt tggacaattt ctgcccactg gtttatccca agaagtgaat
    23101 tcacattctg ggaaacggga acaaccatag aatagtctgt ttttcttaga ttttcgttca
    23161 atgacttgtc cttcatgaca tactgggcaa gtcacaccga tttcttttac gattggtttc
    23221 gtattccgac aatcaggaaa attactgcaa gcataaaact tcccatattt ccctaatttt
    23281 atcaccatcg gatgtccaca gacatcacaa tcgaatcctg ctggttcatc tttgatttga
    23341 attttttcga ttttttcttc cgcattcgtc agttcttttt caaacggttt atagaaacga
    23401 tcaaccactt tgacccacgc ttccgtgcct tcttcaattt tatccaaatc tccttccatt
    23461 tctgctgtga aatggatatc gacgatttga gggaagaatt cacagattaa tgaattgaca
    23521 atttctccta gttcagtcgg ctcaaatctt ttttgtgtca attttacata gtagcgtctt
    23581 tggatcgtat caagtgttgg tgcataagtg gaaggtcgcc ctaccccgtt ttcttctagt
    23641 gcacgaatca acgtagcctc actaaaacgt gctggtggtt gagtaaaatg ttgttttggt
    23701 tcaatatcaa cagattggac tacatcgcct tcttcaagtt ctggaagaat attttctttc
    23761 tcttctttgc cgtcatctct accttccaca tacacttgca tgaatccttt gaatttgatt
    23821 tttgaaccgt tcgcaatgaa gatgacacca ttttgttcta atgtcacttt cattgtatct
    23881 aaaatagctg gtgtcatctg actagccaca aaacgtgacc agatcaatgt ataaagtttc
    23941 aattgatctt tatctaaata ttgtttgagt tcatctggtg tacgaagcac actcgttgga
    24001 cgcacagctt catgggcatc ttgtgcgcct tgagcatttt tgatctttcg gtgatcatgt
    24061 ctagaaaatt cttttccata cgtatcttca ataaatgctg cggcctctgc ttttgctgta
    24121 tcggcaatcc gggtagaatc agtacgcatg tatgtaatca agccgactgt tccttgttta
    24181 cccaaagtga ttccttcata taattgctgt gctaccatca tggtttttct tgttcgaaag
    24241 tttaacttac gggcagcttc ttgttgcagg ctacttgtag tgaaaggatt cgcagggttt
    24301 cttttgcgct ctttcttttc tactttttta acttcgaagt ctgttccatc aattctagca
    24361 gtgacttctt ttacactttg tgcatctggt aatttctttt tcttaccgtc gattccccag
    24421 aaatttgctt tgaatttctt gcgagctttt ttaaaattac cgtcgatgct ccaatattct
    24481 tctggaacaa attctcggat ctctttttca cggtcaataa taatttttaa agcgacagat
    24541 tggacacgtc ctgcacttaa ccctttcttg accttacgcc agagaatagg actgatcgaa
    24601 taaccaacga ttctgtctaa ggtacgacga gcttgctgtg catctactaa atctacatcg
    24661 atcgttcttg gttccttaaa agctgctttg actgcgtctt ttgtgatttc attgaagacc
    24721 acccgatttt tttctttcag atccaaccca agtaggtacg ctaaatgcca agcaatcgct
    24781 tctccttctc tatccgggtc acttgccaag taaacttttt gagctttttt tgctgcggct
    24841 ttcaggcttt tgatgacatc gccttttccg cgtatagaaa tataatgggg ttcataattg
    24901 ttttcaaaat cgatacccat tttacttttc ggtaaatctc ttatatggcc aacactggcc
    24961 attactttat agtttcgtcc aagatatttc tcaattgtct tggcttttgc aggtgattct
    25021 acaatcacta aatatttata cgccattact gaatggactc ctttccattg tcgtgttcct
    25081 actattaaaa gaggattcat acaaatcgta gctaatcata tccattcaga aaacgtttgt
    25141 caagaaaagc aaatgaaaag tatggtgtta ttctttaaat tctgccaaga tatcttcacc
    25201 cgaaaccgtg caaactgcac cgtcttggat caaatgatga catccggtag aatgttctgt
    25261 taaaatattt cctggaacag aaaaaactgt tcttccaaga tccaatgctt gctgtgctgt
    25321 tatcagagag ccgctttttt tcttggcttc aaagacacat gttcctttag acaaagctgc
    25381 gataatccga tttctcattg gaaaacaatg ctttttcggg ccggattgag gaggatattc
    25441 actcaaaaga agatgatcat ttgcaatcac ctcttgcaag tcacgatttt cagcaggata
    25501 gacttgctct atccctgttc caatgactgc gattgtccgt ccaccatgag agattgctgc
    25561 ttggtgaccg tatgtatcta tccctttcgc gcagccactg acgatcacat atccagcttc
    25621 tatcactggt tttagtaaat aataaactgt ttttttggct aaagcagaag tgtgtcttcc
    25681 accaacaacg cttaacatgt tacaagaaag taaagataga tcaccattat aaaacagtac
    25741 aattggcgga taggtcaagt gaagcagctg agggggatat ttgggatcaa agcaagtgat
    25801 aaacgactgt ttcgattgga ttttgcccca gttagcgtga atttcctgcc aacttttgcg
    25861 aaacagctcc cggtgtttgg ttattttacc tatcttaatg atgtcttcaa atccgatttc
    25921 tttataagga tactgcatca tccagttagc aagtgcccat tttccttgac tactgattcc
    25981 ttttgtataa gcaagtttca ataaattttc ttctatttga tacatcataa aaccgccttt
    26041 cgtctctctt tctaataaga tacgtaaaag cggctgtttt ttattgtaaa tattttttta
    26101 caggtgcaaa acttttacga tggattggcg taattccttg tcgttcaagt ccttctaagt
    26161 gttcctttgt tccataacct gcattatgcg agaaaccata tccaggataa agcacgtcat
    26221 attctttcat caattggtct cgatatactt tagcaatgat acttgcagca gcaatcgaca
    26281 cagatcgtgc atcccctttg attatttttt cctgctgaat aggcaaatcc aaggtcatcg
    26341 catcgatcaa caaatagctt ggtacaatgg acaatttttc tactgcttgg atcatcgcta
    26401 atttacttgc ttcataaata ttcacatcat cgattgtctg ctgatcaacg atcccgatcc
    26461 cgattgccag ggctttttct tgaacttgtt gataaagaag ttctcgcttt ttctctgata
    26521 attgtttgga gtcattcagc cctaatatga tctcattttt cggcaagata actgcagctg
    26581 ccacgacagg tccagctaat ggtcctcttc ctacttcatc aatgccggca atccattggt
    26641 gaccttgtgc gtacccttgc ttttcaaagc aaaacatttc ttcatatttt tccttaatta
    26701 atgcttcctt tttcaatcgt cgttcaaaag aagccagtgc ttgctgcacg cctttgcgtg
    26761 gatcatttct taatgattct agtgtaggat catctattct ctgtatgctt ttcaatcgtt
    26821 ctttgatact ttggatggat tcagtcatca cttttttgct ccatttcttc gcaacgatcc
    26881 agtgtgtatc gtccaagttt tccttgacga atatcatgca cgactaattc gctgccacga
    26941 tcatagtctt ctttataccc acgttttgct gtaatatcca tcagtaattc cggtgccaat
    27001 ttttcttctt gctcgattga taaaccataa cgatcgctga ttcttcctga ataatatcgg
    27061 gcaaaaaagt ctaatccgta aatcgctaaa tcatctaaat ggacaagctg gtctttgatc
    27121 gcgcctgtca gcgctagttt tttgccgatt tcttcatctt caaatttggg ccataaaatc
    27181 cctggtgtgt ctaacaattc caactcatta cctaaacgaa gccactgctg accttttgtt
    27241 acgccaggct tatttcctgt ctgtgcaatt ttcttgccta ctagtcgatt catcaacgta
    27301 gatttcccaa catttggaat acctaagacc attgcccgaa tagcgcgagg cttgatcccc
    27361 cgagcagcat ctcttgcccg tttttctttc aatgcttctt tagccgcagg tactagacct
    27421 ttaattcctt tactttcttg tgccgtgata gctaatgcaa gatggccttg tttacgaaaa
    27481 tattcttgcc acagctttgt ctgttgtgga tctgccagat ccgctttatt caataaaaca
    27541 aggcgaggtt tttgctgaat gatctgatct agcattggat tacgagaaga taaaggtaat
    27601 cgtgcgtcta ccaattcaaa tacgatgtcc acatatttca ttttttcaga aacttctcgt
    27661 cgggcttttg ccatatgtcc cggaaaccat tggatggtca ttgttctctc cattcctttc
    27721 ataccggaat attccccggc tttacttgtt tttttctttt tcaatataaa ttcacttttt
    27781 tattataaag aaattccatc tattagttaa gtgaaagtga accagtcctc attctatcac
    27841 atcttcactt ttttgatgat gcaaattttt attttggttt ctatatatga atctaaattt
    27901 ttgacagcgt ttcctaaata agagatgata gacgaacaaa acagaaagga gacgaaacaa
    27961 atgaatagta tggtttttgt taattttcct gttgctgatg tcaatcgttc cgttgctttt
    28021 tatgaaaagc tgggttttaa aaaaaatgaa gaattttcta ctgaagaagc tggttcaatg
    28081 gtatgggatg acactttttg gataatgctt ctctctcatg atttttataa aaaatttata
    28141 aaagataaag aaatagctga taataaaaaa acaagtggtg ctttgatttc gtttagtgtt
    28201 gaaaatgcgg atgaagtaaa aaaatttgct caaattgcaa aagaaaatgg tggtactttc
    28261 cacgaagtag atatgggaat gcctgaagaa gaaatgtttt cattagaagt ccaagatcta
    28321 gacggaaata cattagaacc cgtatggatg aagatgtaag cagataacta atctgacgtt
    28381 ttttataaca aaaaaacaaa ggcggatgat acgataagta ttctccgcct ctattttttt
    28441 tattcgtaca atctcttttt tacagtttat aaaagcagtc ttctcaccct ttttttaatt
    28501 gttagatgcc agtgtatgta aatcaccaat gtgtcatgac acattggtga ttttatggta
    28561 tccttttatt attaactgac aaaggagaga atattttgaa cactttgatt gcaaaagacg
    28621 tttttagatt gcccgaaatg aatgcaagat tgttgtcgac ctctgctctt ttattagccc
    28681 ttgatgtcat cttatacaag atagcgattg gtcctgctta ttttcaaatc acattcggat
    28741 ttttaagtat ggcgcttatg ggttatctat atggaccgat ctgggctggt ttgcttgaaa
    28801 tgttgtcgaa cactttaaat ttcacgatat ttggttcagg aacgtttcaa gctgcttttc
    28861 ttatcacggc tttccttggt ggatttatta atggcttatt tttatatcat aaaaagataa
    28921 acctgccttc cgtcatcgct gcccaattat tgattatgat cccagtcagc ctttttatca
    28981 attcttggct gatgtctgtt ttgtttggtg cagatttcaa agtaattttt ctaggtagat
    29041 tcatcaggaa tatgatccaa atccctattc aaataatggt tgtttattca tttatcaaaa
    29101 ctttagaggc tagaaaagtg tttaaacgag ctgtttgatt ttacgtacta aggtagtaaa
    29161 ctgattttgg attaaacaat aaagcgtgca gtctcaacag actgcacgct ttattgtttc
    29221 tcactggatc cattttattt catcaagtgg ataatagaca aatcttgctt tacctagaat
    29281 atcagtttta ttgatcgtgc caaacgaacg actatctttt gaaactcttc gattatctcc
    29341 aagtacaaaa taattatctt ccggaagctt ggattgtccc gttagctctt gtagtgtaaa
    29401 gtccgtcgta taggatgcat ttgcatgatc tgatttcagg tttttagtta gataaggttc
    29461 cttaactact ttcccattga tcttcaattg atcattttgg tagctgacat tttctcctgg
    29521 aagaccgatt actcgtttga tataaatcgt gccatctgct aattgaaaaa caacaatatc
    29581 aaatcgtctg atctccgaaa atttttccat cacaaccata tcaccttgct tcaacacgtt
    29641 ttccattgaa ttgccttcca ctggtaccgg gatgaataaa aatccccgca acatgaacgc
    29701 aaggaataca gaaacaagta agtatttgaa tacaagccag aagcgattaa tatagcgttg
    29761 tttttttgtc aatctctatc aatccatccc tctttttttc attctttctt tattataaga
    29821 aaaatatcaa aaaaatgcga ctagatagct gaaataaaaa taattctttc aattaggcta
    29881 ttggacaaaa aacttttttg atcataaagt acaaaactat ctcttatatg tcatgattat
    29941 tttctaaata tttttcccat gcttcgtcaa agatatccat ggacggcaaa tagtcgacat
    30001 tcagttccag ataattagaa atttcttcgt agctagagct gtgcttagga aattggatgt
    30061 ctttaccggc ttctgtagcg aaaacagata aagcatcatg tgtgccaccg cctcgcagtg
    30121 tcattaaata atgaaaaaag cttcgattca cccttcgttc ctccaatttt cttcgataaa
    30181 ggcagcccgg cgtgcatggt ttcttttaaa attttcagga tgctttttat aatactcttg
    30241 atggtcttct tctgctagat aaaatggttg ggctggttcg atttttgtaa cgattggctg
    30301 ttcgaaacgt ccactttcag ctaactgttt cttacttttt tcagcaatga tccgctgttc
    30361 ttctgtcaaa taaaagatca ccgggcgata attgtcaccg cgatcctcga attgtccgaa
    30421 agcgtcagtt ggatcagttt gctgccagta aagttctact aattgttcat atgaaatcaa
    30481 tgttggatca tagataatct ccactgcttc tgtatgtcca gtcgtttggc tttttacttg
    30541 ttcataagtc ggatctggta catgccctcc agtatatcct gacatcactg tatggatacc
    30601 aggaagcgtg tcgaaaggct ggatcataca ccagaagcag cctcctgcaa atattgctcg
    30661 ttccattatg attccccctc taatactact catccgatga ttttttattt tcttttgtct
    30721 tgctttcagt actgctggtg ctagttttgt tggtatttga gttgtttgaa gcatcagagg
    30781 tatcttttgg caaatataga ctaaaccgaa tgtcatcatt tactaagtcg attttatctg
    30841 ctttaatata catcccgttt tgcattcgga attgatccaa cctaagcatg atagtcagat
    30901 catctgtatt gacttcgatc caatctggta atttatagtt tctcttgatc atattcatca
    30961 catctttgat tggcaaactc aatgttccga tagaaagact tctagctttt agttggacat
    31021 ttccgttttc catcacatac ggatcaaaat ataaatagaa atcgatagga aaacctagta
    31081 cttcgaaagt accattgagt agtgcttcat tttccaaata aaatttatat tcaatatcac
    31141 tatctttttg atactcacta aggaaaaagc tgatgatttg attgactttt tctttatttg
    31201 aattgatcgt taagacagga tctccttgtc tttccgtaag agctggtatt tctgggagtt
    31261 ctggttcccg attagcaaaa atacggctgc ctaaaaatac ggtcgaacca agtactaccc
    31321 caagaaggat aaggaaggcg aatttccagt aatttgtttt ctttgttttg tttgaagata
    31381 cgtcagatct tgttttcatg tttattgatc atcctccttc tctaaccatt ggttttgtgt
    31441 ctcgatcagc tgatctctca ctgcatttgc catcaattga taacctaaat tatttggatg
    31501 gaaatgatct tcttcataga gcacattatt tttgatgcca tttagatttt ctgtcgtgct
    31561 agttgtttga tctgttcctt cttctgtgac acctacttcc tgattcaatc cttgataaag
    31621 caaatcattg attgggataa agtagcagtt cggcattttt tttgtcaccg tttctgttcc
    31681 tttgttccaa ttgttaacaa ttgtctgcat gtcagtgatc tcaggaaagt tcaaataaaa
    31741 tggattgtag atgcctaaaa tgtaaatagg tgcggtttta ttgagggatc gaaattcttc
    31801 caatagttct gtgacatttt cctgatagtt tttcagtggc tttttaaagg aattgaccgt
    31861 taacccgaat aaattatttt ggataacttt catcaaatca ttaccgccaa cagtcagtgt
    31921 gataaaatca gctgttttga tattgtttcg aatttcttct tttgttttta ctcgctttaa
    31981 gatctggtca cttcgttcac catttacacc atagttttct gtttcaaccg cggtcaaatt
    32041 ataacggtct tttagatcat ttgcgacaag gggaacgaat cctccttgct tggtttgatc
    32101 tcctactcct tcagtcagcg aatctccgat agctatgtag tgaagttttt cttttttatt
    32161 tggatcttct ctcacagtag ttactggttt cattagtggg ccagctttcg gtatagaagc
    32221 agctaaacct gcatagatga tgatcgcaat taataatggg aacaaaacga ggatcaaatg
    32281 tcgtttcgtt aatttcattt tttcacctct tgtattcgat tggttctaat gttatcaaaa
    32341 attttatcaa aaaggtagtc tttatgaaaa aagaaaacaa ttattttcct aattttataa
    32401 agaaaaagag aataagctgc aagcctttca ggctgagggc ttatcctctt ttcgactaat
    32461 ctacataata catgattgca aacgcgtctt taccagtatg cgtagcgata accggattcg
    32521 tatgcagtac agggatatgc atgtccggga ataattcttg caaaccctct ttgaattctt
    32581 gcgccaattc ttttgcatcc gcatgtgaaa taccgatttg tcgcacattt ggcaattctt
    32641 tcagttcatt tttcaaatta ttaaaccatt tatcgaacgt tttctttcct cgccccttag
    32701 ttacagggat taattcagaa tgggcgaaat tcatcaccac gcgtatgttc aaaacactag
    32761 acagcaaacc agttgttcgg ctgattcttc caccttttac caagttatct agtgtggata
    32821 ttccgatgta taattttgta ttgtcttgta cttttttgac ttcttcaagg attttctcta
    32881 ctgttttacc ttcttttgct aattcagctg ctcgaattac ctgaaaagat aatccttggt
    32941 cagtggtatc actgtcgata accgttactt tcgtttttgt tagattactg gcttgtcttg
    33001 ctgcttctac tgttccactc aagccttttg tcatatggat cgaaatcact tcactgccgt
    33061 cttctcctag ctcatcatac atcgagatga attctccaat tggtggttgg cttgttttgg
    33121 gcagattttt tgctttcgcc atcatttcca taaatctttc gccgtctagt tggtcatcat
    33181 cgggatatac tgttccgtcg atcatgatgg atagcggcat gacacgaatg cctaaagcat
    33241 cgcgtacatt tttttccatc gtacatgaag aatctgttac gatttttaca tttgtcatta
    33301 ttttctctct ctctttcttt aacaagatgc cttattcatg ttaaactaca tgtaagacaa
    33361 tttctatttt tagtataaca gacaaataat gatttttcat taattacacc tagtaaagga
    33421 gccgttttca tggaaaaaac gaaatttaat cgaacgtatg aaatattaaa tgaagtgttt
    33481 aatgcagtca cccatggaat tgggactgga ttgagtatcg cgggactagt ggttctttta
    33541 gtaaaaggtg cccacttgca ttcctccctc catattgtct cttatgctat ctatggatcg
    33601 atgatgattc ttttattttt aacgtctact ttgtttcatt cattgatttt tacaaaagca
    33661 aaaaaggtgt tccaagtatt cgatcatagt tcgatttttc ttttgattgc aggaagttat
    33721 actccttttt gtttgctgag tatccgagga tggctaggtt ggactttatt tgtattaatc
    33781 tggttgtttg cgattcttgg cattatatat aaagcgttga cgttgcataa acgggagaga
    33841 gtatcaaaag tatctacgat catctatatt tttatggggt ggctctgtgt cgtggctgct
    33901 gttcctcttt atcactctct tggaatgact ggtgttattt tgatggtagc aggcgggctt
    33961 tcttacacga taggcgcatt cttttatagc ttgaattcta tccgctatat gcatgttgtt
    34021 tggcatttgt ttgttatgtt aggtgcaggt tttatgtact tctctgtttt attctttact
    34081 taataaaaaa aataaagcta tggatgggac agctctaaat aacagctagt ctatccatag
    34141 cttttttata tcgtcaattc gcctgtcccg ctttttacag gattctcatt acgctgatac
    34201 gtttcaaatt gatgcggata acgatttttt tcatccattt ctccttgact agtattgatc
    34261 agtgaccaat cagaccagtc aacaggtgga aaataagcat ctccatcgaa tacatgatgg
    34321 atgactgtac ggtataatat cgtacaaaat ggcagaaatt cttgataaac agctgaccct
    34381 ccagcgatga aaaagatacc gtctgtttct ttttccagag caagcacgtc ttccacacta
    34441 tgcatgacat gcacgccttc tgctttatag gaagaatctc tcgtcaaaac aatcgtctga
    34501 cgattcggca acggacggct acccatccct tcgaatgttt ttcgtcccat cactagtgta
    34561 tttgcttctg tcatttgttt gaagaatttc agatcatttg gcaaacgcca aggaagacgg
    34621 tcttcttttc caatcaatcc gttttcatcc tgtgcccaaa ttgcagctaa cattttctca
    34681 tcctttctga ttctaaacag cgataggagc tttgatcgcc ggatgtgggt catatccttc
    34741 taattggata tcttccatct caaaatcaaa tactgactgc ttttcctgat tcaaaactaa
    34801 agtcggaaat gcgcgtattt ctcggctcaa ttgttctttc atttgttcga tatgattgat
    34861 ataaagatga gcatctccta atgtgtgaac aaattcgcca accgctaaac ctgtttcatg
    34921 tgcaattagg tgagtcagca acgcataact tgcaatgttg aacggaacgc ctagaaacac
    34981 atccccactg cgttgataca attggcagct tagccgtccc tcttgaacat aaaattgaaa
    35041 catcgtatga caaggaggca aagccatgct aggaacatct tccggattcc atgcagaaac
    35101 gatcaatctt ctagaatcag gagtcttttt gattgcttcg atcacttgtt tgatttgatc
    35161 gataaagcca ccgtcttttg tttcccagtg acgccattga tagccgtaga tgtgtccaag
    35221 atcgccgtat gtttcagcaa aggaatcatc ggttaggatc ttctcgcaaa aaagcttgct
    35281 ctgcttttta tattcttcat tgaattcagg atctgtcaaa catctatggc caaaatcagt
    35341 catatctggt ccattatagt ctggactttt gatgtagcgt tcaaatgccc attcatccca
    35401 aatatggttt ttattttgta atagatagcg gatattcgta tctcctttta aaaaccaaag
    35461 caattcgctt ttgatcaatc caaaaggtac tcgtttcgtt gttaacaaag gaaacccttt
    35521 ttgcagatca aaccgcattt ggtatccgaa taagcttaat gtgcctgtgc ctgttctgtc
    35581 ttctttacga tgcccttctt ccaacaattt tcttcctaag tcaagatacg cttgttccat
    35641 cctttttcct cctaatcttc tacccattca ctcaagtatt cccaccgtgc cattttttct
    35701 tcaagttgtg cttctgtttc agatacgtcg ttttgcaatt cttgtaatcg agtgaaatta
    35761 tctccttgat gattcatctc ttcttggagc aatgagattt tttcttcaag ttctgcaatc
    35821 tcatcttcaa tcgtttccca ttctttttgt tccatgtaag ataatttctt cttttcagca
    35881 ggttccttgc tctgtatttt tggtttcgct ttttcagcag gctgctgggt ctctttttgc
    35941 ttcagtaaat aactggacat gtttccgtaa taaagttctt gttttccgtt tccttggaat
    36001 actaataact tatctgctac cttgtccaag aaataacggt catgggaaac agtgatcaca
    36061 gcacctggaa aacttctaaa ataatcttcc aaaatcgtca atgttgctat gtccaaatca
    36121 ttggtcggtt catccaataa taaaacatta ggttgctgaa tcagcagttt caacaaaaat
    36181 aaccggcgtt tttctccgcc tgaaagtttg cctatcagtg tcccatgcat aaatcttgga
    36241 aataaaaatc gttcaagtaa ttctgctact ccgatttgac tgccatctgc tgtttttgct
    36301 tcttcagcag cttcttgtaa gtaagcaatc atccgtttat ctggtgccat ttcttcattt
    36361 tcttgtgtat aatacgcaag atgaaccgtt tcaccgatag acattgtacc gctatccagg
    36421 ggaattctgc cagctagaat attaagcaat gtcgattttc ccgcaccatt tttaccagta
    36481 atacctagtc tttcccgaga ttgaatcaat aaatctaaat gttctagcag tgtttggtca
    36541 tttatacggt aactgccatc tttgatttcc agtacttttt tccctaaacg ttgtgtcgct
    36601 aggttcagct ctaaatcatc ttcttggttt acttggtaca agttctcctt tagatcttcg
    36661 aaacggttga tccgtgcttg ctgcttggtg ccacgtgcct gtacgccagc cctcatccaa
    36721 gctaattcct gtttataaag ccgcttgcgc ttttcttctt gttctacttc tacacgatca
    36781 cgttctgctt tttctaagac gtaagcttca taatttcctt tatactcgta taattttcca
    36841 aatgaaagtt cgaagattcg gtttgctact ctatctagaa aataacgatc gtgggtaacc
    36901 atcaatagtg cgccacggta ttgtttcaaa tagttttcca accactcgat cgcttcataa
    36961 tctaaatggt ttgttggttc gtctagtaat agtaaatcgg gttcatcaat caacacttgc
    37021 gccagactaa ctcgtttttt ctgaccacct gataaagtac tgattttttt atctaattca
    37081 ctgattccta atttttgcaa aataatcttt gcgttggtat ctgtagtcca agcatcttct
    37141 ttattcattt gttcttctgc tttagcataa cgtttttgca catcagggtc ttctccgttt
    37201 tcccctagtt cgatcaatgc ttcctcatat gctcgaacag tttggatcaa ggggctgttt
    37261 ccttgaaaga ctgcttggag aacagttaat tcatcggaaa attcagctgc ttgagaaaga
    37321 taaccaatac ggtaatcagt tggataaaac actgtttgcc gatcaccgtc gctgctatcg
    37381 ataccggcaa taatatttaa gagacttgtt ttacccgtcc cgttcgtccc aatcaacccg
    37441 atacggtctt tttcgtggac caaaaaagaa atctggtcaa acaaatcttt ttcaccataa
    37501 gtttttttga ggtcagttac ttttaattct ttcaacatgt tccctcctta tcttggatat
    37561 tgtatcataa aaatagtgaa cttcaggaaa atttttttgg tatttgttct ttttgtgttc
    37621 tcaaaaaaag aacaggaccg attcgatcct gttctgatat gttttgtttt ttataaaact
    37681 tgaaaatttt taccttttta ttttattgga ctcgtttttt ttgactttgc tcgaaacgca
    37741 aatcggaaag aaaagttatc agatggtttg ttcatcgtat aagattctaa caaattgata
    37801 ttcctgcgat agctgttcgc agaaaacgtc gtgatttttt cagcaacttc gtattcatca
    37861 atgatttttc tttcaagata ataacctctt agcatttttt tcgtaaacag actatcttgc
    37921 tggatcatcc acgaagaaat caaattcccc gagttcattt ttattccttc aagtttgcgt
    37981 tgctggataa aaaattgaac catcgtttca tcataaatat cagtcaagtt atctaaactt
    38041 tcaataatca actgagtatt tttttgatat gtctctctga tttcttggat atcttcatca
    38101 ctaataaatg tctgacgatc agcatatctt ctttgccaaa acattttcgg atggagaacg
    38161 attcgcatta acctacggac aacaatgaac caaaagccga taaaagacaa aatctggctt
    38221 gtgatagaat gttcgaatcg agaaagaaaa cgggagtaaa aacgataacc attagaagaa
    38281 agcttgcccg aacgataact ttcatccaat ccatcccgtt cgatcgacaa aatcagtgct
    38341 tgtatttctt gtacttcttg cttttcatca tcggttaaat cttccaagta cagatcacgt
    38401 atccgttctt gataattttc tatcactgct tcagtggcta aaaattcttt tgtattacga
    38461 tcaatttcct ttatttcttt tcgcaaaact tcaacgacct cttctaaaat catcaaagca
    38521 ttcaaatccg tgcttttcgc ttcctctgtt tccgtcagca taggcaagac aatgatccct
    38581 atgaccaaag tcactaagat gacacccgcc gtcagaaaca aaagcaaaga ccgctggtaa
    38641 aacatcatat tattgattga aaatggcaaa ataaaaatcg tagccaaact gactgttccc
    38701 tttacaccgc caaatgttaa gatcaagatc tcgttcaact gttttttgaa ctttttactg
    38761 ccatctttga atacataaaa aagactgata gaaatgaatc tgatcacaaa aagcatgaca
    38821 gagattaata cgataatcgc taataaaaga ccgtttggat ataaaccgtc tccccatact
    38881 ggcgagaaca cttgcgtcaa ttcgattcct aaaaatataa atactaatgc attcagtgta
    38941 aaagcaatag ttgtccatgt actgtgggac aagctcgaca attctgcatc aaacacagag
    39001 attttcctaa aaccagaagc ttggagaata cctgctgcca ctgcagcaat gattccagat
    39061 acatcaaatg cctctgccaa tacataggct agaaaaggaa gcaaaagttc gatcagcaga
    39121 taccctgtga catcttgtgc tgatgctttt tcgatcaaat gaattatttt ttgtttgaac
    39181 cagacaagca aaaagccgat caaagctccc ccaatactag aaactactag actcatcccc
    39241 gcgtttactg ctgaaaaaga tccggtgatc agcgcaccaa gagcaaactg gaaggcagta
    39301 acaccagatg catcattcaa aagaccttct ccttccaaaa tatgcatcgc ctttttaggg
    39361 atattcactc gtccagaaag agaactgact gctaccgcat ctgtcggacc taacgctgct
    39421 ccaaaagcaa agcaggcagc aagtgggaca cttggcaaca ggaatgataa cgtcgcacct
    39481 accccgacaa gggtcaaaat gactcctcca aatgccaaga acaaaattgt cccgaaattt
    39541 ttgagaatcg aagaaatatc tgctttttct ccttctctaa ataacaatgg tgcaataatc
    39601 ataactaaga acaattcagg ttcaaaatcg attgattgtc cccactctgt cagacctaat
    39661 accactccaa ggaaaatttg gatcagtgga gctggaatca ttggcaaaat gcggctagct
    39721 atgttcgata aggtgatcgt tactgcaaat acaataacta actcagcaaa ttccatcgtc
    39781 catccccttt attttttatt ttgtgtaagc atttttaaaa attgttcttt tttctttaaa
    39841 attttggttt cgactacttc aacctgtgtt tggttcccct ctaattcaca ctgtacacgt
    39901 tttgactcca aacgaagcag atcatgtttc agacgttcca actgacgata catcaatata
    39961 tttcttttac gcaacttaca aagtatttga cggcggtcat ccatcgaaag ggcgccatag
    40021 cgatcatgca acagtttttt ttgttgttca aaactctctc tcattttcca gatctcctat
    40081 acacaaactt ccatcattat agcaaagttc tttttggatg aaaaatattt cattgtttca
    40141 tcgtttattg ctagttagaa atttccataa atttttcaac gcctcattct attccaaata
    40201 gtatcagata tcaagtaaaa cttaagaaag ataaaagttt ctgacaaaag gatgtttact
    40261 ttcccattcc tgcctttctt gttcttttat cacaacaaaa aaatggggct gcgacaaaaa
    40321 tcttgtcaca gtcccttatt ctgaataaac ggtgtggaag agacagccta tcagtagtaa
    40381 taagacacat ctctttcaca gcctcatttt tgcgtaaaaa tcgatttatt cgaaaaattc
    40441 cccgtataca tcttctacac gttgatctgg attgatcacg atatacaagt tacctgtttt
    40501 ttcgctgatt tttgttgatt gatattgatt gtctaatcct tctgttcctt tatctagata
    40561 tgggaagtac acaagatcag gtgtgccatt tcggtaaagg atttccattc gctcgatatc
    40621 ttcgtatttc aatgcgcgat taaacatgcc catttccagt ccgcctaggt tgatatcatg
    40681 tgtcgcaact gcgtcccctt catggaagat ttcgatttta aatccagcac acggatggat
    40741 ttcaacaaat tcactgccat tgattcgtcc aaaacttgtt gtgatttgtt tgatccaaag
    40801 atcgccgata tgacggcggt tgatcgtcca ggtttctcca tttctaaaat aaaattttag
    40861 cgctgtcatt tctttactca ttaaaaagac tcctttatga tgtaatttat tcttgtacta
    40921 cctcagttta gcacaaattt atgtaagtgg tcacatctta tgttttttct tctaatgacg
    40981 tatctgccca ctttaagtag ccaacaaagc tgagcagata cagtctagtg ttttttaaat
    41041 caatttttct ttcgataaaa aatccaaaac ctgtttttta tcatttttta ttctttgttc
    41101 tacgacggct ttttcagcta attgcaaagc ttcactaacc cacttaccag gtttttttcc
    41161 agtttcttct agcaagattt taccatctac tgctaattcg cttaatgact tgataggtaa
    41221 acgatcatag gattctccta cggcatccat ctgaggtgtt tcgtcaaaat agatcatcaa
    41281 ttcttctact tgcagtgcat gttttttgcc taagaagtac aattcgaatg gttccaaagc
    41341 tccagtttct cgttgtcgta gtccttggac aagtgcttga acgtctttaa tcatttggtt
    41401 agaacacttc cacgatttca aaaaggaacg aatctcattt tcttttagat ccagttggct
    41461 gatcaataat gcccatgctt ggctctcttc tttcaatggg acggatggta attcagcaaa
    41521 acgtaaaagt gcttcgcctt cttctttcaa accgggacag caaatgtagc actctgtttc
    41581 aataaatgca tggattcccg cggcccgttc atttcccaag agcatcttga tgaattccac
    41641 atttatacgt tctacagata ttttacctaa tagctcgtgg ttttctttga tggcgtagaa
    41701 ggtttcttcc tctaatttga accctagttg actgacaaaa cgcaacccgc gcatcattcg
    41761 taaggcatct tcatggaacc gctcatgagg attgcctaca gctcgcaaga tctgttcttc
    41821 tagatcttgc agaccatcga acaaatcgat gatttctcca tcttctttca aagcaaacgc
    41881 attgatcgta aaatctcttc ttttcaaatc ttctgccaac gaacgaacga attcgacatg
    41941 atctggtcta cggtagtcct gataagttga ttccgtccga aatgtggtga tctcatattg
    42001 ttcatcattt tctaatacca acacagttcc atgttcgatc ccaatatcta tcgtttttgg
    42061 aaaaagctgt ttgatttctt ctggaaatgc gcttgttgcg atatccacat catggattgg
    42121 ctggttcagc aagatatcac gaacacttcc acctacaaaa taagcttcat atcctgcatt
    42181 ctctaatttt ttcagaactg gaattgcctt ttggtattcc agaggtaatt gttttaattt
    42241 catttttcca acctttcctg cgtgtttctt gtcctgagat aaagactcag ttgcatggtg
    42301 actgtttgac aagtccgttt cagagtcttc aaggccagga ccacttcatc ttgtttactc
    42361 gtccttacgc tcaaagcgat tatggtctct ttgattgaat ttttccatgt ttttttcaaa
    42421 aacttcagtt aagtcgatat tcaatgaatt agccatgatc atcgtaacga ataaaacatc
    42481 accaagttct tctgctaccg agttaactgg ttcagaagcc tttttgcttt tttctccata
    42541 agtgtggttg acttctcttg ccaattcacc tacttcttca gttaatcgag ccatctgagc
    42601 taatggagag aaatacccca ccttgaattg ctggatatat tcatccactt cctgctgcat
    42661 actgtataaa gaacgctttt tatccatctt tttccctcca aaactatctt accaaaactt
    42721 taacgcaaat cctagataag agcaattgag aaaatcgaat ttccatgcta catttaggaa
    42781 ggaatttcta aatggaaatt ctgtgaaaat acataattga aagctggaat tcatatggtc
    42841 aaacgaaaaa cagtaaaaga agttcttttt atcattatag gaacaagtat ttatgcattt
    42901 ggtcttgttt acttgaacat cgctaatcat ttagcagaag ggggagtctc agggatcacc
    42961 ttgatcttaa gagctttatt tggtattgat ccagcttata cgactttatt aatcaacatc
    43021 ccattgattt tactaggagg aaagatcctc ggtaaacgtt ccttggccta tactgttcta
    43081 ggtacacttt ctttgtcatt ctttttatgg atctggcaaa gggttccact agaaatcaat
    43141 ttacagcatg atctactgat cgtttctcta cttgcgggtt tagttgcagg tgtaggaagc
    43201 gggatcgtct accgcatggg tggaacaaca ggcggcagtg atattatcgc tcggatttta
    43261 gaacaaaatt acggcatcac tatggggcgt tccctattgg catttgatat catcgtctta
    43321 cttgcttcat taacctatat cgacttgaaa cgtatgatgt atacgttgat tgtttcgtat
    43381 gttttcagtc gtgtgattga ttcgatctta gatggcggat attctgcaaa aggtctactt
    43441 gtcgtctcca acaaaagcga agagattgca ccactactga tgaccggtct gcaaagaggt
    43501 gtgactttcc tttctggaga aggcgcattc tctggtaatt caaaaaaaat catctatatg
    43561 gtcgttagct ctagtgaatt aactgaagct aagaggatcg tccacgagat tgacgaaaaa
    43621 gctttccttt caatcatcaa tgtgcatgaa gtggaagggc aaggctttac ttatttgaag
    43681 ccacagacaa gattactgaa aaaactataa gaaaaaagac aaagataggc tatgaggaaa
    43741 gattccacat ccagctgacc tttgtctttt ttagtactat actattttta actaattgtt
    43801 atgttcactt acccggttac ttttcttttg tgtctgcaaa aggatctttc ggttaacttc
    43861 atcagataat ttcaaaaaag catccctatc tccatcttct agtgcttgat cgatttgagc
    43921 ataaagcatt tttagttttg cctcttcttc tttttcttga aaatatcgtt caattaattc
    43981 agtatcttct tcactgactg aagaatccca agaagaaaat ggattgtctt ctaagataga
    44041 tagatattct cttgtctgcc aagcattttc gaatatacat tccacatata aaggcttttt
    44101 ccaattcaaa cggatttcat gaaaaatctg gtctgtgtcc gtaaattctt ttccctgcaa
    44161 aaacaatttc atgggttccc cttcaacaga tagatcactg atctgcagtc ctcgatccgc
    44221 aaaattcgcc ccttcaacaa agtggacatt gcttaaaatc gcttcatgat tggcaagata
    44281 attcaagatc caaaaaactt ctcttcggct aaaagataca tgattgacca tccacgttaa
    44341 aaaattcttc ttttcccgta catcaattag catttttctc acctctctgt taggtcatct
    44401 aataatgaca gtgcctccat atctcctggt tcaagtgtta aataataagt caataattct
    44461 tgcgctcttt tcagctgccc ttcttctctt aagaaaaagg catactcttt caagaaatct
    44521 ggttcatgtg atagttcatg ataagcctgt tcatagtgta cagctgcaac ggtaaagtct
    44581 tctaattcat tataagcatg ggctaggttc cattctgcat aaggattagc agtttcttcc
    44641 atctgattga tcacttgtat cacatcttca tatctttcat catccaagta aagattactt
    44701 aaagtaagta atgtttcatc ttgtttgtct cctacttcta aagctttcag taaaagttct
    44761 tctgctcgct gtctatcatg cagacggaaa gcattttccg aggccaggtg ataaagttcg
    44821 acttggtaag gattttcttt gattccttct tctaacactg tttgtgcttc ttcaatcatt
    44881 tcttcttctt gaagagcttg tcctagatat agatataacg attgataatg cggattaact
    44941 tctcgaagtt cttccagata gttgattgcc tgctgatttt ctttcaattg aagattcgta
    45001 aaagctagct ggaacagtcg atcatctgtc ctttcttctt tcagtgcttc ttctaaaggt
    45061 acgatagctg cttcgaattc tccttgcata cttaaggatt gtcctaaacg ttcctgcatc
    45121 gagattcctg aaatttcatt tatcccgctt gccaacaatg tttcataaac cactgctgcc
    45181 tctttgaaac gatcaactga aaaatacaat tcagctagcg caaactggat caatggttca
    45241 tcaggaagca acccagctgc ttctttcaat tttgcttcac tcacttcagg gattccgata
    45301 acttggtaca aatcagctat cgccaataag ctttgcggat agtaatcact ttgcttatcc
    45361 actttttcca ggtattcaaa agctaagtcg atctcattat cttcgattgc aatttctgct
    45421 aacgggatgt tcagtccgtc attttctggg tattggttga tcagttgttc aaaaatctgt
    45481 tttgcttcga tcaaaaagcc aatagccagc aattcttcgc ctagttcagc taatatatct
    45541 gctgggtctt cttttaatgc tttttctaaa aagatttgtg cttgtgacaa gtcttcatct
    45601 gataaagctt gcaacatttt ttcgctattt gtattcattt caattccctc ttatctcact
    45661 gacgatttgt tgaaataccg tcattgttct caataattct ttttcgtttg gatgttggta
    45721 tccgtctatt atacctattt tttctaaaac aagtattttt ttgctttttt ctgccaaaaa
    45781 aagaactttt tccaaatact ccatctttga aatctgttcc agccagtgga ttggatagcc
    45841 aagcaagtcc agccacacaa aaaagttttt tagttggaaa tcaaaaggat atgcttggag
    45901 attccacacg aaatgaaaca tcattcctaa aaattttttc atactagcag aaagtagatg
    45961 gccattttcg gtcagataaa aagcttgttc aaacagttta ccataatttg acaggttttc
    46021 tgcctctaat tgataaaaat agatcatttc ttcgatcatc ccggcaaacg gccgagtcgt
    46081 taattgcttt ttatttggat agtttttata cagattttgc aaaaaacgat gatcacaaat
    46141 cattccgcaa cagataaaag tcaaaaagtc aatctgcttt ccgtccacct gccgctcgct
    46201 gattgtttga tcataaacga tgcgttctgg cagattgatg gtttgcagca ctacacgatt
    46261 tggtagctgc aaaatcgtcc gctgcggtgt taatgctcgg cttagagaac ggatcgatac
    46321 agggatcatc catagtgatg aatcaagggt tgtatgtttt tgaaaaaaac ctgccagatc
    46381 catgatccct tcatttccaa atccgatgat aaacatggat tgattttcgg gatagcgttt
    46441 gacgaaatca agcaggttct ttaattctgt taaatgattg cattgagtgt tggcacaaat
    46501 ataccagtca ttgtttgctt gatttgcaaa taacgggttg atcttatctg caaacaaatc
    46561 ataatagcgc tgattcgtta aaaataagat tggctgatca atggaaagtt ctcttagctg
    46621 actgactagc gtttctccgt aaaacacttt cgtcaacgca tcttctactt gataatcaag
    46681 ttccatacgc atccctcctc ttcttatttt tattttacca ttagtaagca aattctagaa
    46741 aagataagag caaagctcac ctcataactt gcaaataaat aaaaattaaa taaaatacat
    46801 gtgttttcta tgtatgacat acggattcgg aatctctgtc tcttatttat tccttttctg
    46861 ctaggaaata aaaagaaaag cacttgtagc cctagagcca caagcgcttt ttcaactgtc
    46921 ttatttaaca gcgtctttta atgctttacc tggtttgaat gcaggtactt tgctagctgg
    46981 aatttcgatt tcttcaccag tttgtgggtt acgacctttg cgagctgcgc gttcgcgaac
    47041 ttcaaagtta ccaaaaccga ttaattgaac tttttcgccg ttagctaaag catcttgaat
    47101 agttgaaaat acagcatcta ctgctgcagt tgcatctttt ttagttaaat cagtagctga
    47161 agcaactttt tcgattaatt ctgctttgtt tgccatggat agattcacct cctccacaag
    47221 agatatgata gaaatatcat ttagttaaaa ctttctgagt ggtccagaag tttaaaaaga
    47281 aatattgatt aacttcaata ttctgttatc acgatatcat atgaaccgct taatagcaag
    47341 gtttttacca attttcacat gcttttttta gtcatagaaa cgtaacaaac gaaactgtct
    47401 ttttcttttg aaaaaaaaac gtcgatatgg taaaatgcct attttctcct acgagggata
    47461 attcggatgg acgtcccttc aaaagtaaat gcttttctga tttgattttc taagaaacgt
    47521 tcataagaaa aatgcatcaa ttcctcttca ttgacaaaaa cgacaaatgt aggtggtttg
    47581 acagcgactt gtgtagcata aaaaatcttc aggcgttttc ctttatctgt tggtgttgga
    47641 ttgattgcta cagcatccat aatgatatca ttcaacacag ccgaagagat acgaagattc
    47701 tggttcatac ttacttgttc gatcatttca ggcagacgtt ccaaccgttg tttagtcact
    47761 gcagaaacaa aaacgattgg agcgtaatca agataccgga attcatcacg aatctcttgt
    47821 tcgaaatcac gcattgtatt ggtttctttc tttacaagat cccatttatt cacgacgata
    47881 ataattccac gaccagcttc atgggcgtaa cccgctactc gcttgtcttg ttcccgaatc
    47941 ccttcttcag cattcagtac catcaaaacg atatcagaac ggtcaatggc acgcattgca
    48001 cgcatcacgc tgtatttttc agtattttcg tatacttttc cgcgtttacg cataccagct
    48061 gtatctatca ttaagaattt ctgaccactt tcagaaacga agtgggtgtc gattgcgtct
    48121 cgggtcgttc cttcaatatc cgaaacaatt acacgttctt ctcctaaaat cgcattgatc
    48181 aaagaggatt taccaacatt tgggcgacca atcaaactaa acttaatcgt gtcgtcgtcc
    48241 tcttcttcag tctcttcaga gaaatacttc actgcttcat ctaaaatatc accaatccct
    48301 agtccatggc ttcctgaaac aggataagga tcgcctagcc ctaaggaata aaattcatag
    48361 atatcgtttc tcatttctgg attatctact ttattgactg ctaaaatcac tggtttatta
    48421 cttctgtata aaattttcgc aaccatctca tctgcgtctg tcacgccttc gcgtccgctg
    48481 actacacaaa tgattacatc tgcttcttca atcgcgattt ctgcttgatg cttgatctga
    48541 tccataaaag gttcatcgcc aagatcaatt ccgcctgtgt cgatcacgct gaattctcga
    48601 cctaaccatt caccttttgc ataaatacga tcacgagtta ctccaggagt atcttcgaca
    48661 atcgagatac gctcaccagc gatgcggtta aaaatcgtag acttaccgac gttcgggcgg
    48721 ccaacgattg caattgttgg atttgccata ttatttcctc ctcacaagtt tccaatctca
    48781 cttagtttaa cgaatgcatt gccaactttc aagcatagat tgtcaattaa acgaagtatt
    48841 tttattcctt attgaaatac taatcgcttt tcaaaagaaa aactgagaca aaagcagctg
    48901 ctttcatctc agtcacagat acaaaatcaa ttatttttca gaatcatcgg ttgctttttc
    48961 ttctacttct tctttcaacg catcacctaa aatgtctccc atagtaaatc cagtattttc
    49021 ttctggtaat tcataagact caacattttt tggttcttct tctgaagctg gtttttcttc
    49081 taaagctttg atactcaatg caatacgatg ttcttctgga tggatctcta atactttcac
    49141 tttcacttcg tcaccttcat gaagcacttc atgtggtgtc gcaatatgtt tatgtgaaat
    49201 ttgagagata tggactagcc cttctactcc agggaacact tcaacaaagg caccgaagct
    49261 tgtcaaacgt ttaactgttc cgtctaatac tgtgccaact ggagcttttg tatcgatttc
    49321 tgaccaaggt ccaggctgtg tgtctttgat tgacaaggaa acacgttctt gttcaggatt
    49381 gatagacaac actttgacat ttacatcatc attgacagcc aatacatcac ttggttttgc
    49441 tacatgacta tgtgaaatct ctgagacatg gactagaccg tcaattccgc ctaggtcgac
    49501 aaatgcgcca aaatcagtaa gacgtgcaac acgtccactg agaacatctc cctcatggat
    49561 agttgaaaga atttcttttt tcttttcttc tctttcgttt tccactaccg ctttatgcga
    49621 taagatcaaa cgattttctg atggttcgat ttcgatgatt ttaaagctca atgttttgcc
    49681 tttatagtct gaaaagtctg caacaaaatg atcttccacc attgatgcag ggacaaaacc
    49741 acgtacaccg acgtcaacga ctaaaccgcc tttgacaaca tttgtaacag gtgcttcgat
    49801 gaccttgccc tcttggaaat ctctttcgat atcttcccaa acttttttag catctaaacg
    49861 gcgttttgaa agtagatagc tgccgttttc tttatctttg ccgatcgtac tgataacgac
    49921 taaatctaat acatcaccga cttttactac ttcgctgata tcttctaccg gcaaagttga
    49981 taattctttt gccggaacga ctccttcaac tccagcccct tcgattccga caatcacttg
    50041 tttgtcttca atgactaaaa cttcgccctt aacaacatcg ccaactttta cttcttgtac
    50101 gcttttcatt gcgtcttcca ttgactggtt gttctcttga ttttgatcaa attctgtcat
    50161 aacacttgtc ctcctaacca acattctgcc gtaagtacgg tactgttttt agtttaattg
    50221 attattcaaa aaaaataaag cgatttcgtt cgttttcctt gaaaaaacaa ttgtttttca
    50281 ttttttttct taatttaaaa aagaagataa ccttttttca aaacaacagc ttttattgct
    50341 gcaacgactt ctggaatcga tttgccagtc gtatcgatac gaacagcatc ctctgcttgc
    50401 ttcagcggag agacgtccct tgttgaatca taatggtctc tttcctgtat ctctttcgtc
    50461 agtgtttcaa gatcagtcgg aattcctttt tcttggttct ctttgaaacg tctttctgca
    50521 cgctcactta cgcttgctac taaaaagatt ttcacttctg cattcggtaa tacagctgtc
    50581 ccgatgtctc ttccgtccat gacaacgcca ccgcgttccc ctatttttcg ttggacagca
    50641 actaattctt ctctgacttt tccatgtgca gagacttcag aaacagcttt tgtgacatct
    50701 ggttgacgga tttctaaagt cacatctttt gatgctatga atacatgctg tccatcttct
    50761 tgttgcgaaa aagagatagg atactttttg atcagcgaaa ctagcccttc ttcatctgaa
    50821 aaagatacat tgttcgtaat agctaaataa gttactgcgc gatacatggc accggtatct
    50881 gtataaatat aattcaattc ttttgctaat atcttggcaa cggtactttt cccagatgaa
    50941 gcaggcccgt cgattgcaat actgatttgt gtcatgatat aactcctttt tctcagaaaa
    51001 aaagccgcaa agcgcggcta ttattattta attcttaatt cttgaccagg gtaaagcata
    51061 aagttgtttg gatctaagcc attcaattca aacaattgat cagtggtgat ccctgcacgc
    51121 tcagccactt gttttggacc ttcgcctgct tgaacagtcg ttgttgaacc ggctgcagct
    51181 gatgaagaag gtgttgtttc tgctgcattg ctgcttgaat cccctgcttg ataagttgcc
    51241 tcacttgagg aagtcggtgt tgtctctgct gcaatactgc tttctgacgt tacacctgta
    51301 tcttgagaca cagtagattc ttccgcgatt gtactagatt ctactgttga agtctcagtt
    51361 gactcctctt ttgttgtact tgtagaactt tctactactg atgtcgaagt ttcagaagaa
    51421 gttgctgctg ttgcattgtt gcttgatcca tttctgatcc agaaataagc acctgctgga
    51481 atagcgatac ataagaccag taaaatcaaa aatagcgaaa gaaataatgt atttcctttc
    51541 ttttgttgtc tctgagaact tcttgatgaa acttcatcat ctgtatcgta gattggttgt
    51601 tcccatggtt cttgtgtttc gttattttct gtagattgat gtctatcttt tctgctcact
    51661 gttttacctc ctaaactcta tcgtgtgtat tataccatag gaaaaagtgt cttgtcctaa
    51721 aaaatcaatg ttccatgttt tttttaaata aatttagtaa aatcgttccc caatgaagtt
    51781 gttcagtctt agaaaaaagc ttcctctttg gcagaagttc tgcttttgct ccatcaatat
    51841 cacaacaatt ctgcggcttt tcggagagtt tttcgccaaa ataagctaag atgaattttc
    51901 tgcggcagtt ttcttcatta atatagcgaa gcatctgctg caggcggaat tctttttctt
    51961 tttcctgacg tttgagccgt tccacccaat tttctggttt ttcagactgc tggatcagct
    52021 ccatccattt tttttgcagc tcatcaaagg gagcttgctc tgtggcatat tccaaataaa
    52081 gctcaaaact ttgtcgctgt tctctagaaa gttgattaaa gaaataatgg atacgttcat
    52141 ccccactttg ataaaaaaga attgctgcac tttcttcctg atctctgcct gctcgaccga
    52201 tttcttgtac atagttttct agactgtctg gcaaatcata atggaccaca taacggatat
    52261 cagatttatc gatccccata ccaaatgcat tcgtagcaat gagaaactgc agctgatttt
    52321 ttacaaactg ctgttgaagt tgtcttcttt gagctgcatc aagaccaccg tgatagtatc
    52381 caactgtaaa acgttccctg aataaatgat acaatcgttc gacttctttt tttgttgcac
    52441 aataaatgat tgccgctcct tgtgctcttt ccatgaagtg ttcaagttct tgttcttttt
    52501 gctgcgtttt ccgaacaaaa agcgagatat tttgccgatt gactgattgt ctgatctctt
    52561 ttggtggtcg atcaaatagt acatgacgta tatctcttgc tactaaatct gttgctgtcg
    52621 ccgttagtgc cagtgtgacc gggtttccta aaagctttcg gatttttcct aactgttgat
    52681 attctggacg gaaatcaact ccccattgag acacgcaatg agcctcatct actacatata
    52741 acgcaatatt ttgttttttc agatgctcta aaagagaagg attagtcaac atttcgggac
    52801 tcaaaaacaa aaatttatat tgcgatagat gacggaggac gtatcttctt tcagattgcg
    52861 aaagtaaact attgaaagca gctactcgtt tctcccctcg tttttgtaat tgcgtcactt
    52921 gatcttccat tagagaaagc agcggtgaca cgatgatgac cagaccttcc attaaatacc
    52981 ccgtcaattg atagcaaagg ctttttcccg ttcctgtagg caaaatagcg agagtatctt
    53041 ctccatcaag caacgcctga ataatttctt cttggccggg acgaaatgaa tcaaatccaa
    53101 aatatttttt taattcattt attaacattc tgtatcgctt cctttctcaa tagatagatt
    53161 tgatacaaac gaaattctcc ataatctaat tgtccatcta cattccattc gctaaagcgc
    53221 cactctcgca cggaatcctt atttggttcc aaacgttcga ttgtttctgc agagagaatc
    53281 cactcgtatg gaaaatcatc aaaaaacaag gcccactcaa taagatgatc tgttactgtt
    53341 cctcttttta aatgacggat tgccatgatc tggtcaattg tctgaccatt cataaacatc
    53401 tgcttggtga tcatcatgct ttgattgaaa ttttgctgta ataatgaatc gatcaaagcg
    53461 tgccaaagcg aatctggccg tttttcgatt tgtgctaaca aaaggtggat acatctgctt
    53521 tgttgcagat aaaccgctga ctcatcattg ttttttgcca gctgataagg aagcagccct
    53581 gttcgctcat ttccagataa ttggttagct aaaaaatctg ctgcttcttc tggtatctcc
    53641 gaaaacagct gcaccaaact ctcatacgca gtatcaatca aaatttcacg tggcaattgg
    53701 ctttcactaa gccatttttt tagttggaaa gtataaaaag gacttgtctc tgctggaaga
    53761 tagtcttgaa tacccgttgc cagattagaa attacttgaa cagcaaattt aatgagccgc
    53821 caactagttt cccctgttct gccatagcgg tcaaaacgca aaccagtatg ttctatttga
    53881 tgttcggaca acatatcagc ccctgcaggc gttagctttg cttcattttc atttatttcg
    53941 atccaacctt gctgcgcaat tttttgcaaa atttgataaa acttatcctg cttcaattct
    54001 ggaaaactgt tatggataaa caaaagttcg tgggtaaatc cataaataag tactgaagtc
    54061 gttcgttttc ccacaaggag ttggtaaaga gaactaatcc gcagcttgtg tcctgatgaa
    54121 aatagcgata aaataaaaac aatcatatta ttctccttaa gttaggatgg ttagaaatgt
    54181 cactactatg taaacttgta cctgaacgct gtattgcatg cggtctttgt caaatcgaag
    54241 cgccagatat tttcgattat gatgaagaag gaatcgtttt atttgcccaa gaaccagagg
    54301 ctcatcaaca gttcgtgatg ccggaagaag aaacatatgt aaaaaaagcg tatcaaaaat
    54361 gtccagttcg agcgatttta ttagaaaata aaatataaat ataaacgaaa ctttaaaaac
    54421 gtacactaag ttctctaaac ttgaaaataa gccgggatct gtttctcttg ttccgtgaaa
    54481 tcccgactta ttttgaaaga ttcatttgct atctatagtt aattgactag ttttttcacg
    54541 gaccctatag gacccattta tattatttca actttttcag ccagttttcc aatgtattga
    54601 cgatcacagt ttgctggtct gcgttagaaa tttctgcctc tccatctcct ttttgctcac
    54661 catagctgcc aaaacctcca tgatttccgc cattgattga tacatactct gttctttccg
    54721 gtaaatactg cttagcttct tgataagctt cctgattcaa tactttatct tttgtcgccg
    54781 tgatcgataa aacaggaaca gctgattctg tcaatgttcc ttttttgtcg ggataacttg
    54841 ccatgaagaa tacccctttt aaatgtttgt ctgaatgatt cttattgaca taacgacttg
    54901 ccattacgcc acctaatgaa tggccaccga tcacataatc ggaatttgga aaatcttctt
    54961 tgaccttatc cgctttgttt ccgcccatca ctgctagatc aagtggcatt ttgacaatag
    55021 cgactgaaaa gccgtttttt gctaaatctt gcgcccaaat actataactt tctggctcta
    55081 cgagagcacc aggataaaaa ataagtaatg gagactttcc atgattcttt ttctctcctt
    55141 caaaaaataa gtaatcttct ttgttttttc cttcttttac caacacttgc gcttctgacg
    55201 atggttcgta cgtattttgc tgtatatagt aataaccggc tccaccgagt aatcctaaaa
    55261 tgatgactaa gccaattagt attcgtctaa atattttcac tttctcccac cttttctatc
    55321 tgagtgaccc ctttttctta atcaagtatg attatacctt aaaaaaataa gagagaaatg
    55381 caaactttcc agcatcaaat aaaaaaagac ggaatatcca tttgaatatc cgcccttttt
    55441 gtatgtttat ttttatttag cacataaacg atacacagct tctgcataaa tttccattgc
    55501 tttatacata ctacttaatt cccatcgttc attcgcctgg tgcataaagt caggagtatc
    55561 agggaacatc gcaccgaatg ccacacactg gttcatcgta cgagcaaaag tagcgccgcc
    55621 tgatacaaac ggttcagtca tgtctccagt aatatcgcga tatgtcccca atagattttt
    55681 cactaactca ctgtctagtg gcacgtataa tgaatcaagg aagtcaaatt cttcataagt
    55741 caacccatat ttttctgctg ttttagttaa tttagctact aaatcatctt tcttgaatgt
    55801 aacagggatt ctcatatcta caccgatttt tgtttgttct ggtgtgattt ccaaacttgc
    55861 aaagttcatc gttagctcgc cggattgttc atcttctgtt ttgcccacga cagcttcacc
    55921 agttgcattt tcttgaacta attttcctaa gaaattgatt gggccaaaat caaatacttc
    55981 tgaaagagca attgccagac gagaaatagc attcactcct tgtgctgcat ctttcgcgtg
    56041 gatactttta ccaagaacga cgatgccttc accttgttct tcgaaatcga attcgtgttt
    56101 tttcaatgct tcttttactt cagaaagctt ttctccagag taaggagctg catcaggaac
    56161 aacattcaac gctcctccag cttttacaga aaactcgttc gttcctggtc ctgtcaagta
    56221 agcttgcaat aagccttttt ctgcataaat taaaggaaat tcagcatctg gcgcaaatcc
    56281 ttgcgtaatt ccttcttctt tttcgttata tttttctaaa caacgccata aattttcttc
    56341 atctgtacca aagataaaac gaatacgtgt cttgaattcc acgccagcat caatcaaagc
    56401 tttgacggca tacattgccg caatagaagg acctttgtca tcttgggatc cgcgaccaac
    56461 taaccagccg tcttttatag ttggatcgaa tggttttgtt tcccaattat tttcgtcccc
    56521 tgctggaaca acgtccatat gacacaagat accgaataat tcatctccag agccaatctc
    56581 tgaataaccg taatagcctt ctggatcttt aaatgttcta aatcctagct tttcactgat
    56641 ttccaatact ttatccaaag cttcaatcac ttttttaccg aagggatgtc cttgtcctga
    56701 atctgcttca tctagtacgg aaggaattcg gatcaattcg ctcaatgatt ctaatgcttg
    56761 ttcatgatgt tgttctgtca caaatttttt catgatatta tcctcctaat atgttaaaaa
    56821 gggtcatgtc aaattcctcc gacacaacct cttcttctca aataatgacg ttttaagcct
    56881 gctccatcag caagcagaat gttcttaaca aatgatgaaa gaaaaaacac tcactgaatg
    56941 gagctattga cttatccacg tgcttatcga tagccgttta tcggtttctt cattcttatg
    57001 atagaccttg tacctgtatt tgtctaggtt tagaacattg ctgctacacc taggatcaca
    57061 cagatggcta caaataatat cgcaattaat ttaccggtaa atttccacca cactgaaaca
    57121 tcgaaacgag caattgctac agcacccatt acgatagcag atgttggtgt aattaagttt
    57181 actaaaccag atgcagattg ataagcagtg attactaaat ccttaccgac gccggcaaat
    57241 tcacccatag gtcccatgat tcccattgtt gcagcagcta agccggaagt tgaaggaatc
    57301 aagaatgaca tagggatata gaaaataaat gtaataatga tgaatacact tgaagataat
    57361 gaacttaatc cttgttcgcc ccaatgtaag atggtgtctg tgattaatcc attgttcata
    57421 accacttgga taccacgagc aacagctact acgattgcta caccgatcaa atcagaagca
    57481 ccagctaaaa attcagagac aaattcagac tctttcatgc cataagtgat tgctactacg
    57541 atggacatta ctaagaataa catagtaatt tctgggaagt accagtcacc taatggaagc
    57601 atgcttttac ctagaaccgt acctagtacc ggaaggtttg ttaaccagtt tgtcaatgat
    57661 tcaaaaatcg tgaaattcgc attcaaggtt gtccaaggaa tcaaactgat gatcatgata
    57721 ccaaaagtaa taaagaacaa tacattaaca tgtttttgtt ttttcgtgat tacttcttga
    57781 cgaccgattg cttcaatatc gaaatgcttc atatcttctt tacgttggtt gtatactaat
    57841 gattttgttg gatctttttc gatctttgat gcataacgat acacatatac aatagaaata
    57901 gctaacaaaa taacgaacat caagaatcga agaccaatac cttcacccat cgaaatccca
    57961 acagcttgtg aagctacgcc tgttgcaaaa ggatttaccg ttgaagctag acagcctact
    58021 tgagacccta ctaatacgat tgctacagct actactgtat caaagcctac agccatcatg
    58081 actgggatca gtaaagcata gaatggaatc gtttcttctg ccattccgta agtagagccg
    58141 cctaatgcaa ataacagcat caatactgga ataagcattt tttcttttcc tttgaatttc
    58201 ttcacaactg aagcaatccc ggcatctagt gcccctgttt tgttgataat acctaaaaat
    58261 ccaccaacaa ccaaaatgaa gaaagagatt gggattgcag caggtgtttc tttagttagc
    58321 tcccccgctg gtacacctag catcccattg attggcgcca tgaaaatatc ccacagccct
    58381 tgaggatttt gttgtactcg ttcatatgat ccagcgacga tgttgcctgc atcgtctaca
    58441 ctatagtgcc cagctggtat aaaccaagta agtacagcga ttactgcaat aataataaat
    58501 aagaccgtat acgctgaagg catttgaaat tttttctttt ttgtttgttc catcttcttc
    58561 ttcctttctt ttccgttaga gacaacaatt ttggctctaa tgttatttta tcaaaaagag
    58621 tatcagaaca aaaataataa cacgcatttt gtaaaacttt tgttcaaaaa gttcgttttt
    58681 ccctattccc tcctcttttt tcaggttttt aaagctttct tctttttcat tgtagcgttt
    58741 cctttttttt ataaacaaac attttcgtct tttaaaagga gaagaattt
//
LOCUS       DAFLWC010000006        55483 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.006, whole genome shotgun sequence.
ACCESSION   DAFLWC010000006 DAFLWC010000000
VERSION     DAFLWC010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 55483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55483
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.006"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            137..994
                     /locus_tag="L1V17_000347"
     CDS             137..994
                     /locus_tag="L1V17_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HBN1235141.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            1109..2029
                     /gene="pstC"
                     /locus_tag="L1V17_000348"
     CDS             1109..2029
                     /gene="pstC"
                     /locus_tag="L1V17_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBN1235142.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            2029..2913
                     /gene="pstA"
                     /locus_tag="L1V17_000349"
     CDS             2029..2913
                     /gene="pstA"
                     /locus_tag="L1V17_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBN1235143.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            2928..3734
                     /gene="pstB"
                     /locus_tag="L1V17_000350"
     CDS             2928..3734
                     /gene="pstB"
                     /locus_tag="L1V17_000350"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBN1235144.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            3750..4508
                     /locus_tag="L1V17_000351"
     CDS             3750..4508
                     /locus_tag="L1V17_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBN1235145.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGINLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            4521..5198
                     /gene="phoU"
                     /locus_tag="L1V17_000352"
     CDS             4521..5198
                     /gene="phoU"
                     /locus_tag="L1V17_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBN1235146.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            5436..5735
                     /locus_tag="L1V17_000353"
     CDS             5436..5735
                     /locus_tag="L1V17_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235147.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGRLMNTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKK"
     gene            5761..6468
                     /locus_tag="L1V17_000354"
     CDS             5761..6468
                     /locus_tag="L1V17_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBN1235148.1"
                     /translation="MSIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLL
                     NISILFVVIGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYE
                     ELNYLTRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQV
                     GRDVIGSMTNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVL
                     SIPISVLFFLTVRRLKR"
     gene            6465..7232
                     /locus_tag="L1V17_000355"
     CDS             6465..7232
                     /locus_tag="L1V17_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBN1235149.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            7332..8900
                     /gene="liaX"
                     /locus_tag="L1V17_000356"
     CDS             7332..8900
                     /gene="liaX"
                     /locus_tag="L1V17_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HBN1235150.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEITQVQL
                     STTTGSIYLKDTDK"
     gene            9197..9517
                     /locus_tag="L1V17_000357"
     CDS             9197..9517
                     /locus_tag="L1V17_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HBN1235151.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            9517..9867
                     /locus_tag="L1V17_000358"
     CDS             9517..9867
                     /locus_tag="L1V17_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBN1235152.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            10034..10972
                     /locus_tag="L1V17_000359"
     CDS             10034..10972
                     /locus_tag="L1V17_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBN1235153.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            10987..11817
                     /locus_tag="L1V17_000360"
     CDS             10987..11817
                     /locus_tag="L1V17_000360"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBN1235154.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            11861..12886
                     /locus_tag="L1V17_000361"
     CDS             11861..12886
                     /locus_tag="L1V17_000361"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBN1235155.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            12901..13839
                     /gene="galU"
                     /locus_tag="L1V17_000362"
     CDS             12901..13839
                     /gene="galU"
                     /locus_tag="L1V17_000362"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBN1235156.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKKLEAEGSKIDHNPKGITEIKEEKKK"
     gene            13964..14404
                     /locus_tag="L1V17_000363"
     CDS             13964..14404
                     /locus_tag="L1V17_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBN1235157.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            14407..15009
                     /locus_tag="L1V17_000364"
     CDS             14407..15009
                     /locus_tag="L1V17_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBN1235158.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDTKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(15077..16183)
                     /locus_tag="L1V17_000365"
     CDS             complement(15077..16183)
                     /locus_tag="L1V17_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBN1235159.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLASIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            16393..17394
                     /gene="ccpA"
                     /locus_tag="L1V17_000366"
     CDS             16393..17394
                     /gene="ccpA"
                     /locus_tag="L1V17_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HBN1235160.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(17697..20042)
                     /locus_tag="L1V17_000367"
     CDS             complement(17697..20042)
                     /locus_tag="L1V17_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBN1235161.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            20321..21223
                     /locus_tag="L1V17_000368"
     CDS             20321..21223
                     /locus_tag="L1V17_000368"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBN1235162.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
     gene            21436..23211
                     /locus_tag="L1V17_000369"
     CDS             21436..23211
                     /locus_tag="L1V17_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBN1235163.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSFYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYSSSKKMLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYSIAAIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHAVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFAFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTAFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            23468..24685
                     /locus_tag="L1V17_000370"
     CDS             23468..24685
                     /locus_tag="L1V17_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBN1235164.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEENTLCSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFLNRLTPYALILIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKEALATQMIKKAEGSPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSGKYTGQDRINKRGNPKARK
                     IIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVATVACMNKLLKCMHAMVRAH
                     TEYDYAYAVSVDH"
     gene            complement(25132..26718)
                     /locus_tag="L1V17_000371"
     CDS             complement(25132..26718)
                     /locus_tag="L1V17_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HBN1235165.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
     gene            26969..27193
                     /locus_tag="L1V17_000372"
     CDS             26969..27193
                     /locus_tag="L1V17_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HBN1235166.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            27335..29086
                     /locus_tag="L1V17_000373"
     CDS             27335..29086
                     /locus_tag="L1V17_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1235167.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLAPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAALLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGCSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQKLEAKIEGGEA"
     gene            29086..30870
                     /locus_tag="L1V17_000374"
     CDS             29086..30870
                     /locus_tag="L1V17_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1235168.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPTITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLTKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            31328..32179
                     /locus_tag="L1V17_000375"
     CDS             31328..32179
                     /locus_tag="L1V17_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBN1235169.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELYQVIQKKYKDTFGCVEKIADFLAEIFNYQMSTDEKMYLTIHIARL
                     VHENRCK"
     gene            32276..34162
                     /locus_tag="L1V17_000376"
     CDS             32276..34162
                     /locus_tag="L1V17_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1235170.1"
                     /translation="MGKYQELASKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGVVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTALLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPAFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNPGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEAGETDDRQKRSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSEAGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEEEGYSLETPVIVTNYTDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(34203..35105)
                     /locus_tag="L1V17_000377"
     CDS             complement(34203..35105)
                     /locus_tag="L1V17_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBN1235171.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            35335..36738
                     /locus_tag="L1V17_000378"
     CDS             35335..36738
                     /locus_tag="L1V17_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBN1235172.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPTMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMNELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            36735..38171
                     /locus_tag="L1V17_000379"
     CDS             36735..38171
                     /locus_tag="L1V17_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBN1235173.1"
                     /translation="MMGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFP
                     VITGKKKMFEFDENHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGD
                     EKEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENL
                     CRVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASA
                     IATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPA
                     YALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFAS
                     VKNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDY
                     RIDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGN
                     GTLARSKKKSFNWYKKVIDSNGENLSND"
     gene            38316..39242
                     /gene="trxB"
                     /locus_tag="L1V17_000380"
     CDS             38316..39242
                     /gene="trxB"
                     /locus_tag="L1V17_000380"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBN1235174.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            39455..41182
                     /locus_tag="L1V17_000381"
     CDS             39455..41182
                     /locus_tag="L1V17_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBN1235175.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     TIIQKMTEE"
     gene            41198..41548
                     /locus_tag="L1V17_000382"
     CDS             41198..41548
                     /locus_tag="L1V17_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBN1235176.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAIIQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(41632..42492)
                     /locus_tag="L1V17_000383"
     CDS             complement(41632..42492)
                     /locus_tag="L1V17_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBN1235177.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPSVEFNLFRRT
                     FVTDEKTLMQALQDALEEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            42584..43012
                     /locus_tag="L1V17_000384"
     CDS             42584..43012
                     /locus_tag="L1V17_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBN1235178.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            43174..43350
                     /locus_tag="L1V17_000385"
     CDS             43174..43350
                     /locus_tag="L1V17_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBN1235179.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            43377..43823
                     /locus_tag="L1V17_000386"
     CDS             43377..43823
                     /locus_tag="L1V17_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBN1235180.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(43979..45358)
                     /gene="brnQ"
                     /locus_tag="L1V17_000387"
     CDS             complement(43979..45358)
                     /gene="brnQ"
                     /locus_tag="L1V17_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBN1235181.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            46064..47035
                     /locus_tag="L1V17_000388"
     CDS             46064..47035
                     /locus_tag="L1V17_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBN1235182.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            47059..49251
                     /locus_tag="L1V17_000389"
     CDS             47059..49251
                     /locus_tag="L1V17_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HBN1235183.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            49268..49744
                     /gene="ybeY"
                     /locus_tag="L1V17_000390"
     CDS             49268..49744
                     /gene="ybeY"
                     /locus_tag="L1V17_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBN1235184.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            49728..50123
                     /locus_tag="L1V17_000391"
     CDS             49728..50123
                     /locus_tag="L1V17_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HBN1235185.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            50138..51037
                     /gene="era"
                     /locus_tag="L1V17_000392"
     CDS             50138..51037
                     /gene="era"
                     /locus_tag="L1V17_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBN1235186.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            51180..51992
                     /gene="recO"
                     /locus_tag="L1V17_000393"
     CDS             51180..51992
                     /gene="recO"
                     /locus_tag="L1V17_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBN1235187.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKSGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            52376..53293
                     /gene="glyQ"
                     /locus_tag="L1V17_000394"
     CDS             52376..53293
                     /gene="glyQ"
                     /locus_tag="L1V17_000394"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBN1235188.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            53295..55370
                     /locus_tag="L1V17_000395"
     CDS             53295..55370
                     /locus_tag="L1V17_000395"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBN1235189.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEIIPFEILDVKTDRASRGHRFLGEDVTFTHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKNHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
BASE COUNT        17978 a         9938 c        11791 g        15776 t
ORIGIN      
        1 agcatagaaa cttttaatga gatagttttt tttacaatta tgagaattta ttttgttatt
       61 taatgatttt gattcgtttt catcaagtaa tgaaaatgat aaaataaaca tactttagga
      121 ttaaaggaga tttctaatga aaaaacttaa attattctta ccaataatag gattagccat
      181 tcttttatca ggctgttcaa agtggattga tcgaggagaa tccattacgg ctgttggctc
      241 ttctgcttta cagcctttag tagaaacagt tgctgaaact taccagacag aaaatcctgg
      301 aaaattcatc aatgtacaag ggggcggaag cggaactggt ttgtctcaag tacagtcagg
      361 agcagtcgac atcggaaact ctgatttgtt tgcggaagaa aaatcgggga tcgatgcctc
      421 agcattagtc gatcatcgag tagcagttgt tgggatcact cctattgtga acaaggatat
      481 tggcgtaaaa gacatcagta tggaaaacct gaaaaaacta tttacaggcg agatcaaaaa
      541 ctggagtgaa gtcggtggaa aagatcagcc agtagttata ttgaaccgcg cttcaggaag
      601 cggaacccgt agcacgtttg aaaaatgggt attggacgga gaaacagctg ttcaggcaca
      661 agaacaagat tcaagcggaa tggtgcgcca gatcgttgcc gacacacccg gtgcaatcag
      721 ctatgttgct ttttcttatg tttccgatga tgtagatacg ttgaatgtta acggtgtaga
      781 accgacagat gaaaatgtga caacgaacaa atggacgatt tgggcatatg agcatatgta
      841 cacaagagat catccaaaaa aactgacaaa agaattttta gactatatct tatctgatga
      901 agtacaagat aacatcgttg gagaactagg ttatatccct gtttctcata tgaaagtcga
      961 acgtgattgg caaggaaata tcgttaaaga gtaatcttta cacaaaattt acaaacttag
     1021 ctaaactttt acatgttatt aaaaccaaat tgatgttcaa tttgtacact gagtgagtat
     1081 gttaaacctg attaaggggg agtcatctgt ggaagatgtg aaaaaagtat tattaacaaa
     1141 atcaaaacgt tcaaaaatgg aacagcgtgg aaaattcatc agttttttat gtatcgcgct
     1201 gatcgtgttg gttgtattat ctatttttta ttttgtagct agtaaaggat tggccacctt
     1261 ttttactgat aagatcaatg tatttgattt tctgtttggt acagattgga atccaagcca
     1321 aatcggagca aatgggaaac caatggtagg ggcattgcct atgatcacag gttcgtttat
     1381 tgtgaccttt ttatctgcta tcgttgccac gccatttgcc attggtgcag cagtattcat
     1441 gacggagatc tctcctaaaa acggaacgaa gatcttacag ccggtcatcg agctgcttgt
     1501 aggtattcct tctgtcgttt atggttttat cggtttatca gttatcgtgc cttttgtcag
     1561 aagtattttt ggcgggacag ggtttggtat cttagctggt acatttgtgt tgttcgttat
     1621 gatcttgccg actgtcacaa cgatgactgt tgatgcatta aaggcagtgc cacggcacta
     1681 tcgggaagct tcattagcgc ttggtgccac aagatggcaa acaatctaca aagtcgtgct
     1741 acgagcagcc gtgcccggga ttttaacagc agtcgttttt ggtatggctc gtgcgtttgg
     1801 tgaagcctta gctatccaaa tggtcatcgg taatgcagca ttgatgccaa caggacttac
     1861 tactcctgct tctacattga cgtccatctt aacaatggga atcggaaata caatcatggg
     1921 aacagttgaa aataatgtgt tatggtcatt agcgctgatc ttgctattga tgtcattatt
     1981 ctttaatatc gtgatccgta tgattgggaa gaaaggagag ctgaaataat gaacgcaaaa
     2041 cgctcagata aaattgctac aggtgtttta tatatagttt cggggatcat cgtattgatt
     2101 ttagcagctt tactacttta tatcttagtt cggggaatac cgcatatttc atggtccttc
     2161 ttgaccgaac cttccaaagc ctaccaagaa ggcggtggaa tcgggatcca gctatttaac
     2221 tcgatttatt tgcttttgat cacgatgatc atcagttttc ctatttcttt aggtgcgggt
     2281 atctatcttt cagaatatgc tggaaaaaac tggctaacag atgtgattcg cacgtcgatt
     2341 gaaatcttga gctcgttgcc ttctgtcgtt gtcggtttat tcggtttctt ggttttcgtt
     2401 attcaattcc agtatggttt ctcgattatt tctggtgcat tggctttgac tgtattcaac
     2461 ttgcctcttt tgactagaac agttgaggag tctttacaag cggtccatta cacacaacga
     2521 gaagcaggat tggccttagg tttgtcacgc tgggaaacag tgataaaagt ggtggttcca
     2581 gaagcgacac cagggatttt gactggtgtg atcctaagtt ctggaagaat ttttggtgaa
     2641 gcagctgcat tgatctatac ggctggacaa agtgcacctg cgttagattt tacgaactgg
     2701 aatccattaa gtgtttcaag cccgatcagc attttccgtc aagctgaaac attagctgtc
     2761 catatttgga agatcaatac agaaggcacg atgcctgatg gtgtttctgt ttcggctggc
     2821 gcttctgccg tgttgatcat tgctgtttta ctgttcaact tcggcgctcg tgcgattggc
     2881 aaacgattat accgaaaaat gacttcagcc taaggagaag aagcaaaatg aaaaaatata
     2941 actggaatga aacaaatgtc atcaccatgc caaaagagaa agaagtagca ctatatacgg
     3001 atgatctaca tgtctggtat ggcgacaatg aagcaatcaa aggagtggat ctggaatttg
     3061 aaaaaaataa gatcactgca ctgattggtc cttccggctg cggaaaatct acgtatcttc
     3121 gttcgttgaa tcgaatgaat gatgggatcg ctaatacgaa aatcactggg aaaatcatgt
     3181 atcaaggcgt agatattaat gcgcctcaag tggatgttta tgagatgcgc aaacggattg
     3241 gcatggtttt tcaacgtcct aatccgttca gcaagtcgat ttatgacaat attacatttg
     3301 ctttgaaaca gcacggcgaa aaaaacaaaa agaaattaga tgaaatcgtt gaaacaagct
     3361 tgaaacaagc tgccttgtgg gaccaagtaa aagacagctt ggacaaaagt gccttggctt
     3421 tatctggcgg gcaacagcaa cgtttatgta ttgctcgtgc gatcgcgatg aaacctgata
     3481 tcttgctgct agacgagccg gcaagtgctt tggaccctat ttcgacagga acggttgaag
     3541 aaacacttgt aaacttgaaa gaagactata cgatcatcat cgtgacgcat aacatgcaac
     3601 aagcagctcg tatcagcgac tatactgcct ttttctatct aggaaaagta atggaatatg
     3661 acaaaactaa caagatattt accagaccaa aaattcaggc aaccgaagat tatgtgtccg
     3721 gtcattttgg ttaagacgga ggcctcaaca tgacaaaaga aattatttca tctaaagatc
     3781 ttcatctgta ttatggaaag aaagaagcac taaaagggat caatctaagt ttcaatcaag
     3841 gggaaatcac tgcgatgatc ggtccttctg gttgcgggaa atccacttat ctgcgttctt
     3901 tgaaccggat gaatgacctg attccgaatg taacgatcac cggaagtgtt ttatataaag
     3961 acaaagacat ctatggtcca aaaacagatg ttgttgaact aagaaaagaa atcggcatgg
     4021 tattccagca gccaaaccca tttccttttt ctatctatga aaatgtcatc tatggattga
     4081 aattaaaagg ggaaaaagat aaaaaagtcc ttgatcaagt agttgaagaa agcctgaagg
     4141 cagcgtctgt ttgggatgat gtgaaagaca aattgcataa aagtgcttta tctttatccg
     4201 gtgggcagca gcagcgtgta tgtatcgcac gtgttttggc agttaatccg gaaatcatct
     4261 tattggatga accaacaagt gcgcttgatc ctgtttctac tgggaaaatc gaaagtatgc
     4321 tgttagaatt aagagagcgg tatacgatga tcatcgtgac ccataatatg tctcaagctt
     4381 cacgtatttc agataagacg gcattctttt tagatggtca cttgatcgaa tacaacgata
     4441 cgaagaagat attcatgaat ccagaaaaac aagagacaga agattatatt tcaggtcgat
     4501 ttggataagg aggaaacgga atgctacgta cacaatttga agaagaattg ctgaatctcc
     4561 ataatcagtt ctacgaaatg gggatgatgg tgagcagcgc cgtgcacaag tcagttcgtg
     4621 catacatcaa acacgataaa atcttagccc aagaagttat cgaaaacgat ataaatatca
     4681 ataacatgga aacacgcttg gagaagaaaa gttttgaaat gatcgcattg caacagccag
     4741 ttacaactga tttgcgtatg atcattacgg tcatgaaagc tagctcggat ttagaacgta
     4801 tggccgatca tgcggtgtct gttgctaaat ccacgattcg cgtaaaaggg cagacgagaa
     4861 taccggaaat cgaaaaagag atctccgata tgtccgatta tgtgaaaaaa atggtggaca
     4921 acgtcctagt tgcttatgtc aaaacagacg aaaaagacgc acgtacgatc gccaatatgg
     4981 atcaaagagt caatgactat ttcaatcgaa tctataatgc aacaatcaaa aatatgcagg
     5041 aaaatcctga gacagtcatc agtggaacag actacttgaa tgttgccagt tatctagaac
     5101 ggatcggaga ctatgtgaca aacatctgtg aatggatcgt ctacttggct acagggaaaa
     5161 tcactgagtt aaatacgaac cacaatgaga ttttctaaac tgaagctgtg attatgccgt
     5221 ttgtttagga aaagaggttg tgaaatcagc ggttgtgaaa aagctgttct gcatcaagta
     5281 ataagaacag tcaaacaaaa aatagctcct catatttttc gtttggctgg acttattacc
     5341 gcagatgcaa gcttttgaac accgtttatt cgggaaaggg tttgtgacaa aacatgtcac
     5401 aaaccctttt catcatttca tagaaaggat aaagaatgca aaaaaaaatt agcatcatca
     5461 ctatattttt tatttgtgtg cttacttcat gggttattca gcatcaagct gctttatatg
     5521 aagtacctgt catcgagatc gaaaaagtac gaataaaaga ggatcatcaa ttgattacag
     5581 gaagactgat gaacacggat caaaaaggag aatcgattta tttatcggtt ccttatcaaa
     5641 aaaatcaaat agaaacagca aatataaaag cgagacaaat gtatctagtc caaatgcatg
     5701 gagatgaatg gcagctagta gcaaaaaaaa aatgatggct ggcttttctt cttcacaagt
     5761 atctccattg gcgccatgtt gcttattggc ggaaaacagg gtctatttgc tttaggaagt
     5821 ctcatcatca atatcgtttt acttttactt ttgttgctca tctttactaa aacagaaggg
     5881 atttctctat taaatatatc tatcctgttc gtcgttatag ggatgattat tagcatattg
     5941 gctttagatg gatggaatag aagcagtata atcaaaattt cagctgcagt tacgagtgtt
     6001 tttttagcat tttttatttg tcttttgaca atgaatcatt ggaaagacca aggactgcgc
     6061 tatgaggaac tgaattatct gacacgaccg tatcgttctg tttttctttc tagcgtactg
     6121 attggaacag ctggaggaac actcgatacc gttatcacag tcattgcgac attagaagaa
     6181 ttgactaagc gacaaccaga aataacagcg aaacagttat ggctttcagg aaggcaagtg
     6241 ggtcgagatg tgattggctc gatgaccaat atccttttgt tcgtctatat cagtgggtca
     6301 gttccatcgc ttcttttata tttaggaaat caatggtcgt tcaaagaaac gatagaacag
     6361 catttatcat tggaattttt acgcgtcatt gctggcagct taggaatagt attatcgatc
     6421 cctatctcgg tcctcttttt tctgactgta aggaggctga aacgatgaat gtacttatta
     6481 tacttgttgg gattttagca atcagcgtgc tacttattgg cggtacgcaa ggtatgtata
     6541 ttcttttagg cttattcatc aatttaggga tctttttcct gttgttattc ggttatcatc
     6601 agaagtggcc gatactggca ttgtcggtca taggattttt attgattgct gtggttatct
     6661 tattttttat caacggttat aatctaaaaa tgcgtgcagc ttttgtgagt atactgatct
     6721 ttttattttg tttcctacta ttgcttccta tcactgattt tttagcgatc caaggtttta
     6781 catcggtaga actagaagaa ttatctggct tagataagac tttagcgatt gattttagat
     6841 tacttacgag atcgttgctt ctgattagtc ttagtggtgc tgttttagat gctagtgtag
     6901 caatttctag tgggacattc gaagtatatc aggcaaatcc gcaattatct ttttaccaat
     6961 tgcgccattc tagtttcgct attgctaaaa aaatattggc gtcaacagta atgacacttc
     7021 tttttgcatt catgggaagt tctttagcgt tgatcctctg gtttattgat ttagacattc
     7081 cttttcagca agtgatcaat gaaaaatcat ttgttctaga atatacgatg gctattctta
     7141 ccacattgtc tgcactactt gttcttcctt taacctgcgt gactacagca tatctcttta
     7201 caaaaaagaa agaacaactc aagatggagt aaaagttaca acttaagtcc tatgacattt
     7261 ttactgaatc agtgcataat atggatgtaa ggaaaagctt gcaaacaatt ttgcttaagg
     7321 aggcaatttc catgaaagaa agagaacgta ttttagattt agtgaaaaaa ggaatccttt
     7381 cgactgaaga aggcttagat ttattagaaa gcatggcaac tgaaaaagac gaaaagcaaa
     7441 taaaaaaaga agcagacaag gtaactgcta gtcataaaga aaaagatcag gcaagtcaat
     7501 tgatcgataa acttgaaaac ggcgaagaag aaatttctga gccagttgat ccaaaggaaa
     7561 gagaaaggca agatcaagaa aacttagaaa agatcttaga tgaactagca actgaagcga
     7621 ataaaacttc ggcgcgtcta gatgaagtaa atgctcaatt cgctgacaat aaggcagcac
     7681 gcaatgagaa acaggaagca ttgatgcagc tgaatacaaa agaagaatta ggcgagttga
     7741 cagaagaaga attagcacag cgtcagacgt tagaagcaga aatcaaagaa ttagaagcta
     7801 gtggcgatac actgttagaa gaacaattga aattagaagc agaattaaaa gatatccgta
     7861 agaatcaatg gtctgagaaa aaagaaacgt ttactgataa gtttgaattg ccagatgatt
     7921 ggaaagatca agcaacagat acactgaatc aagtaggcga aaaaatgtca gaagctggat
     7981 cacagttagg caaattcttg aagaaaacat tccaaactgt ttcagaaaca gtgaatgaca
     8041 acatggaatg gaaagatgtc agcttacgtg tccctgggat tgcgacaacg aaatttgagc
     8101 atgaatttta ctatgaagct cctgcagcaa gtatccttga tatcaaggca gcaaacggaa
     8161 acgtgacgtt aaaaacgtgg gacagcaacg atgtgaaagt tgaagctaag atcaaacttt
     8221 acggaaaaat gggtgctgaa ccatttgaag cattctctga acggagccag attgaggtta
     8281 atgaagatca tatctccttc caaattccaa ataaacgtgt gcgtgcagac cttgttttct
     8341 acttacctaa acgagtatac gaccacgcag ctattaaact tctaaatggc aacatcatga
     8401 ttgaaacatt ggaagctaaa gatatttata caaaatctac gaatggtaac atcatcgtgg
     8461 accaattaac tgcaacgatg ctggaagtag aaggtgtaaa cggcaatatc gatattcgaa
     8521 acgggaacat cttagattct attatcgaaa cagtaaatgg tacagtgaca tttggtgcga
     8581 cagcagaaaa cctttctgtg tctttggtaa atggtgatgt acgtcttacg attaaagaag
     8641 ataatttgaa aaaagtagaa gcaagttcag tgaacggaaa tgtcaaagtc gctttaccag
     8701 atggcatcgg tttggaagga catgctaaaa caagtcttgg aagtatcaac agccgtctgt
     8761 ccaattacga agtagttcgt gagaaaaaag aacggacaaa ccaaatgttg caattccgtc
     8821 gtgtttcaga tggtgaaatc acgcaagtgc aactttcaac gacaacagga agtatctatt
     8881 taaaagatac agataaataa agaggttgtg aaagagatgt tcagccttga gcaataagaa
     8941 gcgattttgt aaaatagctt cccctatttt acaaaattgt gccttattgc cgataggcta
     9001 tctcttgaac accgtttacc aagagattat gaacctgcca attatcgccg agtcacaagg
     9061 aataatttca gaaaaagctc gtcacgtttt atgaatatgg taatttgtga ccgagaattt
     9121 tgcagaaaga caccgattaa gaagaaggtt gtcacaacga ttttcttcat ttaaaatagt
     9181 agaacagagg tgagacatga tgaaaaaaaa gttgacaaaa tccaataaaa atgttgtttt
     9241 gacagggact ttagcaggaa taggagaata catcgggatt gatccgactg ttatccgtgt
     9301 gctttatgta ttcctgagct tagttgcttt tggaagtcca atcattttat acattttatt
     9361 agctttgatt atcccatctg cgcgttctgc acgaacaaac tatggacata acaatgcata
     9421 ttatgaaaaa aacaattatc gtgaacaaac tcgtgaacaa acaaaaaaac gcaaagaagc
     9481 ggaaaaaatc gatgatgacg aatggagtga cttttaatgt cgtactttca acgtatttta
     9541 gttaatacgt taacattcat atcattggct gttctttttc ctgcgatggt ccatgtgagc
     9601 agtatttgga cggccgttct tgccagcttc gtattgtctg tgttgaatat gtttgtcaaa
     9661 ccgattttga cgatactgtc cctgcccttt acattagtca cattgggatt gtttacgttt
     9721 gttatcaatg cagcgattct taaaatgacc tccttttttg tgggagcaga acattttagt
     9781 ttttcttcat tcggtgcagc gttgttagta gctatcttga tgtcgcttgt caatgtaatt
     9841 gtcagtgaac ataacagtag aaaataaaag aaagctgtgc cgaactatcg gcgcagtttt
     9901 tttatttaga atcaggaatg cgttttctat tacattggta attaaataaa aacgtttttt
     9961 ttaattggta gtacttttgg ctagacaatg ataaaatgat agagaacact ctaatagaaa
    10021 tgaggtagca tgaatgtcag aagttgtaaa agttagccaa ttagtgaaaa aattatcttt
    10081 ggaaatcgtg acaggcgacg agaaaagctt agaccgtgtc atcgtaactg gggacatctc
    10141 acgcccagga ctagagttga ctggttattt taattattat tcccataatc gtttacagct
    10201 atttggcagt aaagaaatca gttttgcgga acggatgatc ccagaagagc gtttgatcat
    10261 catgagaaga ttatgtagtg aagatatgcc cgcatttatt atttcaagag gattaccggc
    10321 tccagaagaa atgatccagg cagcaaatga aaatgggata gctgtactgc gttctcccat
    10381 ctcaacttct cgtttattag gagaattatc cagttattta gatggtcgcc ttgcccctcg
    10441 aacaagtgtc cacggtgttt tagtggatgt ttacggatta ggtgtactga ttcaaggtga
    10501 cagtgggata ggaaaaagtg aaacagcgtt ggagttgatc aaacgcggtc atcgattgat
    10561 cgcagacgat cgagtagatg tttatcagca agatgaatta acggtgatcg gagaaccgcc
    10621 taaaatcctg gaacatctaa ttgaaatccg aggaatcggg atcattgatg taatgaatct
    10681 ttttggtgcg agtgcggtac gtggctctat gcaagtccag ttggctgttt atctggaagc
    10741 atgggcaaaa gataagaaat acgaccgtct gggctctgaa gacacgaccg ttgaaatcgc
    10801 ggaagtgggc attccacaaa taaaaatccc tgtcaaaaca ggacgaaacg ttgcaatcat
    10861 cattgaagta gccgcgatga atttccgtgc acgtacaatg ggctttgacg caacgaaaac
    10921 atttgaagaa agattaagtc gcttgattga agaaaactca ggcaacgact agcaaggagt
    10981 gacaatatgt tagcacaaat caatcgagtt gcttttgagc ttgtagggat tcctatctac
    11041 tggtatgcat tgatcatcgt atcaggtatc attatcgcca tgtggcttag cagcagagag
    11101 gctgttcggg taggattaaa agcagatgat gtgacagatt ttatgttgtg gggattgcct
    11161 atctccatta ttggtgctcg cttatattat gttttatttg atcttcccca gtatatagct
    11221 gatccaatcc aaatattcaa tatccgttca ggaggcttag ctatttatgg cggactgatt
    11281 gcaggcgcga tcacgctgta tttttttact aaatatcatt ttatttcttt gtggactttt
    11341 ttagatatcg ctgcaccaag tgtattatta gcacaggcaa tcggtcgttg gggaaatttc
    11401 atgaaccacg aagcatatgg accagacacg acgcgaagct tcttagaaag tctgcattta
    11461 ccgcaattca tcattgataa tatgtatatc gaagggatct atcgtcaacc aacatttctt
    11521 tatgaatcac tttggagttt gattggattt attttgcttt tgtttttacg aaagaaacca
    11581 caccttttga aaaaaggcga agtcctttta tgttatctaa tgtggtatag tttcgggcgt
    11641 ttctttattg aaggattacg tacagacagt ctttactttt taggtgtgat ccgtatttct
    11701 caattattat ctgctgtgtt atttgtcggt acattgattc tatttatttg gcgcagaaaa
    11761 aaaggaaatt taccggatta tgaccgctca ttaggaaaaa atcaacaaat tatctgattt
    11821 ttagagcgtt aaaaatgaaa aaaatttcag gagtggtaaa atgaattata gagtagcggt
    11881 tttaggacca ggctcttggg gtactgcttt ggcacaagtc ctcgccgaaa acggacatga
    11941 cgttcggatt tggggacatc gtgcttcaca agtagaagaa atcaacaccc aacacacgaa
    12001 tcaacgttat ttaccagatc attatctacc cgattccatc caagcattca ccaatatgga
    12061 agatgcagta aaagacgcag atgcggtgct attcgtcatt ccaacgaaag caatacgttc
    12121 tgttgcaaaa gaactagtgc ctaaattgaa tacaaagcca gtgatcatcc atgcaagtaa
    12181 aggattagaa cagggaacac ataaaaggat ctctgacatc ttgttagagg aaatcccagc
    12241 agaaaaaaga aaagctgttg ttgttctttc tggaccaagc catgcagaag aagtagcgaa
    12301 acatgacatc actacgatca cagctgcaag tacagatgca aaagcagcaa aatatgtaca
    12361 agagctgttc atgaataatt attttcggat ctataccaat cctgatgtga tcggtgtaga
    12421 gatgggggca gctttgaaaa atattattgc tattggtgct ggcgctattc acggcttagg
    12481 gtttggcgat aatgcaaagg cagcaatcat gacgcgcgga ttagctgaga tcagccgttt
    12541 aggtgtagca atgggtgcca acccgctgac ctttatcgga ttaagcggag taggcgatct
    12601 agtcgttact tgcacaagtg ttcattctag gaactggcgc gcaggcaact tgttaggaca
    12661 agggcagccc ctagaagagg tgctagccaa tatgggaatg gtcgttgaag gtgtgaatac
    12721 tactcaagca gcgatggaac tagcccaaat aatggaaatc gaaatgccca tcactcaaac
    12781 aatctatgaa gtgctgtatg aacaaaaaga aatcaaaaca gccgcaaaag aaatcatgtt
    12841 acgtgatggg aaaaaagaaa atgaattctc attaacaatt ttttgaagga gcgaatgtat
    12901 atgaaagtca aaaaagcagt tattccagcg gcaggattag gaacaagatt tttaccagca
    12961 acaaaagcta tggcaaagga aatgttgcca attgttgata aaccaacaat ccagttcatc
    13021 gttgaagaag cgttgaaatc aggaatcgaa gacatcttga tcgttacagg aaaagctaaa
    13081 cgaccaatcg aagatcactt tgattcaaat attgaattag aaacaaacct aagtgaaaaa
    13141 ggaaagaccg aattattgaa attagtagaa gaaacgacag atgtcaactt gcatttcatc
    13201 cgtcaatctc atccaaaggg tttaggacat gccgttcttc aagcaagagc ctttattgga
    13261 aatgaaccgt ttgtcgttat gctaggcgat gatatcatgg aagatgaagt accattgaca
    13321 cagcaattaa tcgatgatta cgaacgtact catgcttcta cgatcgccgt tatgcaagtt
    13381 cctcatgatg aaacttcaaa atacggaatt atcaatccag gagaagtatt ggaagatggg
    13441 ttatacaatg tcaaaaactt tgttgaaaaa ccagatccaa gcaaagcacc aagtgattta
    13501 gctattattg gacgttactt attgactcca gaaatttttg atgtattgtc cgagcaacaa
    13561 ccaggagccg gaaatgaaat ccaactaact gacgcaatcg atacattgaa taaaacacaa
    13621 cgcgtatttg cccgtaaatt cacaggtaaa cgttacgatg tcggtgacaa atttggtttt
    13681 atgaaaacaa gtattgaata tggtctaaca catccagaag taggtgcacc tttacgtgag
    13741 tatatcctgt ctttaggtaa aaaattagaa gcagaaggaa gcaagatcga tcataatcca
    13801 aaaggaataa cagaaatcaa agaagaaaag aaaaaataac ccttttttct aacgagcttc
    13861 agctgctaat tgaataaaaa gtagttgaag ctcgttttta tttgtttaaa aaacacgaaa
    13921 atgctatcct tatagaaaag agagacaaga agggagtttg atcatgtcag gaggagaaat
    13981 tgcaggattg atcgcagcaa tcgcctttgc gatacttgtc gtttttatcg ttcgtgtgtt
    14041 gttgcaagtt tctaaaactt tagaaaaagt agatcagact gtagcagaag caaatacgac
    14101 gatcgaaatc gtcacaaaag acgtagatct tttgtctaga caagtagaag gcttgctggt
    14161 caaaagtaat gaactgctct tggatatcaa tggaaaagtc gcaacgatcg atccattgtt
    14221 cacagcagtt gctgatttaa gtgaaagtgt atcagaactt aatcattcta gtaaaaacat
    14281 cgcgacgaaa gtcggcggaa tcggtaaaac gacagctaaa gcgacggttg ccggaaaagt
    14341 cggtgggaca gcgatgaaat tttttaaaaa caaaaaacat actgaaacga caggaggaaa
    14401 ataaaaatgg ctaaaaaagg tggattttta ttaggtgcag tagtcggagg aacagccgca
    14461 gcaatcgccg cgttattgtt agcaccaaaa tctggtaaag aacttcggga tgaattagct
    14521 gcccaagcgg atgatttgat ggatatggct tcagattaca cagatatggc gaaagaaaaa
    14581 tcgactgagt taacaggtat tgcaaaagaa aaagcgcaag atctttctca acaagcaggt
    14641 gatctagcag gtagtgtcaa acaaaaagta agtgaatcag cagatgaagc aggaagtgaa
    14701 tctgacgata tcttgttaaa tcttaaagaa caatcagctg acttatctaa tcgtttcaaa
    14761 aaaacggcag aagatatgaa aaaacctgca gatgaattag gaagtattgc taaagatact
    14821 tcagaagata tcatgattga tgtaaaagac gctgctggta aagcaggaga tactgtcaat
    14881 gaaggaatgt cagaagcaaa accagttgca gatgacacaa aagaaatgat gaaaatggca
    14941 aaagaagatg cgaaagaagc taaaaaagaa ataaaagata caatgacaga ttcatctaca
    15001 aatcactaaa atcactaaaa tcacaaattt atagaataaa aaggtgggag cggactagct
    15061 ctcacctttt ttactcttat ttttctaaaa ctagtaattc ttttggtgta gtcgtgaatg
    15121 gcacacagcc atcgcttgtc acatatacac agtcttcgat acgtacccct actttttcag
    15181 gaatatagat tcctggttca agagagaagc acatcccttc ttcgattact aagtcatttc
    15241 cttctacaag ggaagggaat tcgtggacgg ttgttccgat cccgtgacct aaacggtgat
    15301 tgaaatattc gccgtagcca tagctgttga tcacgtttcg tgcgatttga tcaagttcac
    15361 ctgctgtcac acctggacgg acggcttctt gtgcggcaag ctgtgcttca agagtgatgt
    15421 tgtatatttt ttcttggaag tcggttggtt tttgataagc aattgtacga gtagcatcac
    15481 tgcaatagcc attccaaaca acgccaagat cgaataacac aagttcattc ggtgaaatct
    15541 tcgtgtttcc tggtgtacca tgagggcttg cagcatttgc tcctgcaagg actaatgtgt
    15601 cgaaagacat ttgtgaaaca ccttgttttt tcaattggta ttcgatttct gcaatgatcg
    15661 cttgttcagt cacgccttct ttcactgctt taaagccaat ctcaaatgca acatcggccc
    15721 atttaccagc ttcgatcagt ttgtcttttt cctctagagt tttgatcagt tgtagacgtt
    15781 ggatgatgga agctagatca gtgtaagaat ccgttcccgt caagatatca gagatagcat
    15841 cgaagcgctc gacagtcaag gcgttctttt caatccctac attgccaggc tgaccatagc
    15901 gagcacgaag ttcttttccg atgatctccc aagggttttc gctgtctaaa tagccacgga
    15961 catcatacgc ccaactactg ttttgagcat cttcaacttc caaagcagga gtgaaaagga
    16021 aaggatcttg ttcaagaggg ataaaaagag ctagtacacg ctcatgagga tcactttcgt
    16081 atccggaaaa gtaagcgatg tggccagggt cgctgatata agccaattcg acttggtgtt
    16141 gtgccatcca ttgacgtagt tcattgattt ttacgttatt catttggcaa cctactttct
    16201 aaattaattt tgtattcaat aattgtacca ctgatttatt aaaagaccaa cgttctaaaa
    16261 actgaaaaaa gtaaaaattt tcatgaaaac agagataaaa cggttgcaat tcttgagatt
    16321 atttgatatt ctattttaga aatgtaagac gtattttcag aaaacatata aaatatgaat
    16381 aggagaacac aaatggaaaa gcaaacaatc actatctatg atgtagcgag agaggcaaat
    16441 gtttcgatgg ctactgtttc acgtgtcgta aatggcaatc caaacgtcaa accagcaaca
    16501 agaaaaaaag tcttggaagt tatcgatcgc ttggattatc gtccaaacgc agttgcgcgt
    16561 ggcttggcaa gtaagaaaac aacaacagtt ggggtaatca tccctgatgt cagcaatatg
    16621 ttctttgctt ctttagcacg tggtatcgat gatgtggcaa caatgtacaa atacaatatt
    16681 atcttagcaa attcagatgg taacgaccaa aaagaagtca atgtattgaa taacttactg
    16741 gctaagcaag tggacggcgt gatcttcatg ggtcaccata tcacagacga aatccgtgga
    16801 gaattttcac gttcaaaaac tcctgttgta ttagctggct ctattgatcc agatgaacaa
    16861 gtaggtagcg taaacattga ttatgtatca gcaacaaaag atgcagtaaa caaattggca
    16921 aaaagcggca ataaaaaaat cgcttttgtc agtggtgcgt tgatcgatcc tatcaatgga
    16981 caaaatcgtc tgaaaggcta taaagaagca ttaagcgaaa ataacctacc atatagcgaa
    17041 ggattgatct ttgaagcaca atacaacttc aaagatggtc tatctctagt cgatcggatc
    17101 cataatagcg gtgcaacagc tgtctatgtt tcagatgatg aattagccat cggtattttg
    17161 gatggtttat tagaccgtgg cgtgaaagta ccggaagaat tcgaaatcat cacaagtaac
    17221 aattcactac tgacagaagt agctcgtcct cgtttaacaa gtatcacaca accattatac
    17281 gatttagggg cggtatctat gcgcctattg acgaaaatga tgaataaaga agaagtcgaa
    17341 gaaaaaacga ttatcttgcc ttatggaatc gaagaaaaag gatctacaaa ataataaaag
    17401 gacaaccatt cagaggttgt gagcctgccg tttaactctg cgttacaagg agcaatttca
    17461 aaaaacagca tttcatgttt gatgaatatt gtgactcgtg attcggagtt ggcaggagaa
    17521 caccgtttat tcgggaaaag gggttatgac aaaattttgt ttaatccttt ttttttgtct
    17581 taaaaaagag agaaagtggt tgaaattaca tttatcgtat ataaaacaat ccgtgtatag
    17641 atgctgcatt atgttcacca ccatcaaaaa aataagggac tgtgtattct attaaatcaa
    17701 tcatctttct catctgattc tttggttgct tgattcgctc ttgcataagc tgaagcggtg
    17761 ttccagtaat ctgtatagtt ttcatcggta ccgccaacgc caaatttaaa ggcgcttttc
    17821 ttcggtccat ttttcgccca tagcgattca actgtttttc ctggtgtttg gatggatttt
    17881 ttattgacag taacttttcc aggtgtttga ccagtaaatc cagatacttt tttcttcatc
    17941 acatcagatg ataattcgaa tttctcatca gtgccaaaaa tgtcaggttt tgcttggtaa
    18001 gcttgattga tcagattggc aagataatta gccgaacgta tccttgcttt gctgtccatt
    18061 ccagtattgt catcgtgccc tgcccagcta ctgatggtaa tagacggagt agagacaatt
    18121 agccatgaat ctcggtattc attggtagaa ccagtttttc cgacccaatc tgcttttcct
    18181 agatttccgt ttaagcttga gatggcatct ttgaatggtg tagtgatttt tgcattgatc
    18241 acactgcgca tcatgtcatt catgatcgat gccgttgctt ccgaatagat ccggacagag
    18301 ttgctttcgt gtttataaat tacatttcct gcgttatctg tgatggaatc gatgatatag
    18361 ccttcttcat agacgccgcc gtttgctaaa gcctgaaatc cattggtctg ttgaagcgtc
    18421 gtgacatcta ctgtacctaa aggagcagat tcaacgcccc aattgtcatt tgccgggtag
    18481 ttcatctttg ccaagtagtg ctcgtaagca tattgtttcg atccaccgga attcaacaca
    18541 tcttgatata agtgataagc cgggatattg ttggaccatt ctagtgactc acggacggtt
    18601 tggaaggtgt tcgatccttc gttagtagca ttgacgattt tctcgccagc attttctcct
    18661 tcttgccaag ttgttgcata atctgataca cgggattctg atccgataag ccccatgtcg
    18721 attgcaggtc cataaacaag aactggtttg attgatgagc cagcttgacg ttctgtatcg
    18781 aaggcatggt tattttgatt ctgactgtaa ttccgtccgc caacgaatcc gtagatgcgg
    18841 ccagttctgt tatccatcaa tacatttccg gtttctactt gactgccagc accatcatct
    18901 aacatgtatc cataattttc tacgccattt tgcaatgcag catagacatc tttatcgatt
    18961 gtcgaatgga ttgtatatcc tttattttgg atcgtttgct gtgccttttg ataataagcg
    19021 tcactgaccg atgaatcaga catatcagcg ttgtcttttt cagccaattg ttgtgcaatg
    19081 attcttgttg cttcattcat cacagtataa tacaagaatt ctctgtcagt ctgttctgcg
    19141 atttgttgtg gtagaaagtc ttttgtaagg tcataggctt ttgcttcttc gtattgttct
    19201 ttcgtaattt ggccttcacg atacatactg aataaaacaa aatcttttct ggcaaggccg
    19261 gcagaaagat cttcttttag cgcacctgtg ttcgtgtatg gactatacgt gatcgggctt
    19321 tggggtaatc cagcgatata agcagcttgc ggcagcgtca catcttttgc atctacacca
    19381 aagattcctc ttgcagcttc ctggactcca gcaatgtttt gtcccttatt attacgacca
    19441 aatggtgaga cattcaaata cgtagcaatg atctcatctt ttgaaaagta tttttctact
    19501 tgtgcagaaa gaatgatctc gtttgcttta cgtttgaatg ttgtttcatc tgtaaggatc
    19561 tgctgtttga ctaattgctg tgtcaaagtt gatccaccag aagagccaat accagtagct
    19621 tcagatacta atgctcgtaa aacagcttta ggaacgtaac cttggtgttt atcgaagtat
    19681 tcatcctctg tgctgataat tgcagttttc aataaaggtg aaattttatc agatgaaata
    19741 gtcgtgcgca tcagatctgt ctggattttt gatatctctg tattatctgc ataaacaatc
    19801 tttgacgttt ctgtaatgtt tcctagttct gtctgcagtg cttttttagt cggcaattgt
    19861 gtgtcttcga cgagataggc aaaatagcca gcgcctattc caatacctag agctgcgaac
    19921 atcaaaagaa gaacagtaat aaaaacagtc aatgattgaa aaactctaaa aataatctta
    19981 ggaacaaacc atttttcttt ttttcttcta ttctgttttt ttcgagtatt tttgcgtggc
    20041 aaaagggtca cctcaactaa tggttttatt tcgctaatta tagcaaataa tagaacaaaa
    20101 aaacagacaa ggctgttttt ggcaggaatt tcttttttaa aagagttaaa acgtgagaaa
    20161 atgatctttt ttataaaaga gttcttaagc ttttctttag agaaaatttc agttactatg
    20221 gagaacaggg caaagaaaaa tcaatcattt tctttgtata tcatcttacc aatatatagg
    20281 aattgttagt aacaattgcc tttcaaggag gaatccatcc atgttattag gctcacacgt
    20341 cagcatgagc ggaaagaaaa tgctgttagg agcagcagaa gaagcagcca gttatggatc
    20401 ttcgactttt atgatctata caggcgcccc tcaaaacact agaagaaaag ccatcgaaga
    20461 gatgaatatt gatgccggaa aagcgtacat ggcagaaaac ggtctaacaa atatcgtcgt
    20521 tcatgcccct tatatcatta atttggggaa tacgatcaaa ccagaaatgt ttccttttgc
    20581 cgtccaattt ctgagagaag agattgttcg tgcggaagct ttaggcgcta ctcaaattac
    20641 acttcaccca ggtgctcatg taggggcagg aacagaagcc ggaattgcta gaattattga
    20701 aggcttgaat gaagttttga caaaagaaca gacggcacaa atcgctttgg agacaatggc
    20761 aggtaaaggt acggaaatcg gtcgaacatt tgaggaatta gcgcaaatca tcgatggagt
    20821 aaaattgaat gaaaaattat ccgttacttt tgacacctgt catacgaatg atgccggtta
    20881 taatattaaa gaagactttt caggtgtaat ggaagagttt gataagatca tcgggttaga
    20941 tcggcttaaa gtactccata tcaatgattc taaaaatccg caaggttcgc ataaagaccg
    21001 gcacgccaat attggttttg gaacaatcgg attcgacacg ctgaataaga tcgtccatga
    21061 tccaatgttt gacaatattt cgaaaatctt ggaaactccc tatgtcggca aagataaaaa
    21121 gaaagcttac gcaccatatg gaaaagaaat cgccatgttc aaagcacaaa tattcgatcc
    21181 agaagtgttt cctgagttat tagcagaaga agtgatactc taagattttc tatctgacag
    21241 cagcaaaaaa ggaccaggca cattgccttg tccttttttg tttaagaaac aaaggagtgc
    21301 tttttgcagt ctttttcatc atgcatcttc tcccccctct ttttaaattt agacaaacag
    21361 ggtatactgg tagaaaagta aaaaaacgaa aagtttcaca agcaagtggc aaaacgtgat
    21421 tggaaggacg aaaagatgct gaacacttta aaacccttga tcaaccaact aaaaaagaaa
    21481 catacatact ttattcttgg catagcccta ttatttacaa ttattcgttt gtatttatat
    21541 agtaaagcaa tctatggaac agacatgtcg gcaacctatg atgaccagct gctgattcgc
    21601 tatgctcaaa atattttgga cggtaaatgg ctaggggagt atacgactac aacactttcc
    21661 aaaggaatct cctacagctt atttttagta cttgcacata aactgcatct ttcttatgca
    21721 gttttgttcg gcatgttcag tatttttgcc agtatattgg ttgcactcgc gtttaaaccg
    21781 atcgtgaaga acaagtatct tcttttaagt ttctattttt attttttgtt ttctccgatt
    21841 agttttacac atgaatattc cactcgaacg tatcgtaatg ccctcgtgat tccggctgtt
    21901 gagatcatta tcgcttgttt actagctatt tattaccgta aatatagttc cagcaaaaaa
    21961 atgctgccgt ggtttttagg gctagctgtt tcttttcctt tcttttggtt cattcgcgaa
    22021 gattccatct ggcttcttcc ttttactgta gtcgcgttag gcatcagttt cgtccagatc
    22081 ttgctaggac aagacttttc tttcaaagaa gcaaagaagt taaaagaacg accatttctc
    22141 ctttcgaaac aagaatggct gaaactttca ttgtttttac tccctctagt cggtttctcc
    22201 atcgtctatc agtggatcga atataaaaac gagacaacat atagtattgc cgccatcaat
    22261 gaccgttcga gtggcgaatt tggacgtttg atgaaacagc tgatccgaat agatgacgaa
    22321 acgaacttaa ataaagaaaa cagtgagata tgggtctcgc atgctgcatt aaataaagca
    22381 ttagacgcat ctcctacatt tcatgctgtt tctactcgta ttgacgaatt gtatacgact
    22441 catgcgtgga cccaaggtgg aaaagtaaaa gaattaccag gagatatcat tttttgggca
    22501 ttgcgagatg tggtaagcga atctggttat taccaaaaca atgcaaaaga aaccaatgat
    22561 ttttggaaaa aagtcaatca agaattagaa gaagcctatc aaaagggaac tatcaaaaag
    22621 aaaaaagaat tctatctgat gggatcaggg gatggaaaga cgatgaatga tctgccaatc
    22681 gtatttgctt ttctgaaatc aggatatgcc tatgcatggc gatacaaaga tttccatcaa
    22741 ggggggaatt atagtttcgg tacgcaagaa caagtcgaac aggcccaaga attattgaat
    22801 cttccactaa tggataattg gatcgatagc agtgatccga gaacacctga tttccagttg
    22861 acaaaaacag caaaagtcgc gaatgtcatg ataaaaattt accaagttct ggccattccc
    22921 gtgctgattg cttcaatagc agggatatta cttatgatac taggaaccgc atttgcaaaa
    22981 gctgatcgtg cctattatag ttcctctttg attgtagtca ccggattaat actgacacaa
    23041 ttggtttttc ttttcggcgt ctcgtggttt tgttcttatg cgccagaaaa aaaggattat
    23101 tttttaagtg tctacactgg cgcaggcgtg ccattaacgc aattcatcgt agtaacaagc
    23161 atgctagttt tcagtaaatt gaatctgaaa aaagctttat cttccaaata aaaacatact
    23221 aagattagag gagaacatca ttgacgaatg atgttctcct ctattttcta tttttagatt
    23281 atagtgaaga gtgaaagaaa gttcgaacaa agccttgagg actatgagtc cctatcaaaa
    23341 accgaacttc tttactgtca ttttagaatc aggtttacgt atgttggggc catgagcccg
    23401 tgtataggaa attggaatcg aaatgaagca gtaaagttct ttcaaaactt aaaaaggagg
    23461 aaaacaaatg ccttacattc ttgcattaga tgtttcaatg ggacacagct acagtgtcct
    23521 atacaaagac gacacctgct tatttgaaga cgagatcgaa cacactcaaa gaggatttca
    23581 tgcattactc gaagagatcc agcacttgcc tgaacgtcca ttgattgttt ttgaagcaac
    23641 ggggatttat tccagaccag tcgaaaagtt ctttcaagat catcactttt cttactgttt
    23701 gttaaacccg ttagaagcga aaaaacagat ggaagaaaac accttatgca gttggaaaac
    23761 agataaatcg gatgcccatc ggctcgcaca gactcatctt aaaaatcaac gtcagccaaa
    23821 agaagtacaa agcaattttt acttagagat gcgcgattta gcccgttttt atcaagaaat
    23881 tgagaagaaa atcactcgtc tgcgcatgga tttacacaac tgccttcagt tgacttttcc
    23941 agagcttgaa cagttctttt taaacaggct gaccccttac gcattgatat tgatccgtct
    24001 ttttccccat ccagattttg tattggcatc tactcggaca aaaataaaaa ataaactgat
    24061 caacgaaaca cggaaaaaaa tctccgcgaa tcgtgccgag caaaaggcag atcaaatcat
    24121 ccactatgca cagtgtgcct atccagctgt tgaaaaagac agtatccact gtcaaaaaac
    24181 gatctattac gctgaacttc tccaagattt actcgaacaa aaagaagcac tggcgacaca
    24241 aatgatcaaa aaagccgaag gctctccttg ctttttgttg taccaaacgt tccctgggat
    24301 tggcgcactc acagccgctt tattgctcgg tgaattagga gatatcacac gatttaaaac
    24361 ccataaacaa ttgaatgcct ttgtcggaat cgacatccga cggtatcatt caggtaagta
    24421 tactggccaa gaccgcatca ataagcgtgg taatcccaaa gcacggaaaa ttattttctt
    24481 caccattcga aatatgattc gccagcaacg cgcagctcct aatcatattg tcgattatta
    24541 ctacaaatta aaaaagcaac ctatccctaa gaaagataag gttgccacag ttgcttgtat
    24601 gaacaagctt ctgaaatgta tgcacgctat ggttagggca catacagagt acgactatgc
    24661 gtacgcggtc tcagtggacc attaactaaa ccacttacag tataccactt ctttgcccag
    24721 atcgaaaatt ttttacgaac ggggctttat ttggtgtgcc ttgattttgt cgctttcgtt
    24781 tatgagctat ttttcttaca ccttttactt gactaatcgt aggaaaggga actgtgacaa
    24841 aagtcttgtc gcagttcctt tttccgaata aacggtgctc aaaagcttgc atctgcggta
    24901 ataagtccaa ccaagttaaa aacataaaaa gctgttttta cttggctgtt cttattactt
    24961 gatgcaaggc agctttttca caacctctga tacacggtgt tccagaagta acttcttcgg
    25021 aaataagccg aaatttcaca aaaatttgaa aagcaatttt cttaaattcc ttcttatttc
    25081 ttgaagctgc ccacttctga cacaacctcc tttgtgtaaa agaatcagtt tctactcgat
    25141 ttcttctatc gtttcctgca aacgctgttc atattttttg tttcctttat ataaatcacc
    25201 aatcgtccat gccaacagga gaaggacaag aacaatgatt acataagcga tttgatcagc
    25261 caatgctagt tgagctgagg tggcttgctc gccgaagaaa ctttcgattt gacctggtaa
    25321 tcctcgtaaa ttcaagtaag tcagactaat cacagagaac cagccaagta gttttacaac
    25381 aaatgaattt ttgaatcggc tccccatctc cgcttggcta ttggtcatca tcagtaaagg
    25441 aatcatcgag aatggcaatg caaaagccag aaaaacttgg gattcattca tcaagttatt
    25501 caaagcggta tgttcttcga tcgttccttt tgtacttgta aacaaaacac aaatcaatac
    25561 aggaatcaca gaaagcaatc gtgtgactag tcttcttagc caaattggga tacgcatatg
    25621 gatgaagcct tccatgatga cttgaccggt caacgtacca gtaatagtag agttctggcc
    25681 agaagcaaga agtgctacag caaataaagt agacaagata ccagattttg ctacagcaat
    25741 caagatacca ttgctcatag ctgatggatc agataaagct tcatacagac caaaaaagga
    25801 aggatcttgg acagaaccgg ttttgaatac agccacaccc atgatcaata gcagtgcatt
    25861 gactagaaaa gccattgaca actggatatt agaatcccaa gtagaaaagc gtaccgcttg
    25921 tgctacatct tcttcgtctt ggtgatcgat cttccgagtt tgagaaactg ctgaatgaag
    25981 atataagtta tgcggcatga ctgttgcacc aataatccct aaagctccag tcagcggagt
    26041 ttcgccgccg atgaccggtg agtctgagaa tgtgtgactg ttagggataa atccggcaaa
    26101 caaactgtgc caatcagggt tagacaagcc aacttgatag acgaaaacga ataaaatgac
    26161 gaaaatcaag cagacaacca aagcttcgat tttacgaaac ccgacttttg tcagcaataa
    26221 aaggacgaaa acatctaaca cagtgataaa tacggcaatt accaatggaa tatcaaaaag
    26281 caggtagagg gcgattgctg caccaatgac ttctgcgatg tctgttgcca taatggctaa
    26341 ttcagtcaag atccataaaa tgacacccaa tgtcttactt gtccgtgctc ggattgcttg
    26401 ggccaaatcc atttgggtca cgattcctaa ttttgctgcc atatattgta aaagcatagc
    26461 aatcagacta gacatcaaaa taactgacat caataaatat tggaaatttt gtccaccagt
    26521 gatcgaagtg gaccagttac ctggatccat ataaccaact gctactaatg cacctggtcc
    26581 agagtaagca agaagtgttt taaaaaaact ttttcccttg ggtacatcca ctgttccatt
    26641 tacttcagct aaagataaac catttgtatg ttcaataagt cgatgcttat gaaattgttt
    26701 gttggattga ttattcaaga aaaaaccacc tttcctattt atctacgatt acattctaca
    26761 cctcagaaag aaaaaattaa agaaaaagat ttggtatgcc taattttttt tcgtggcgtg
    26821 tcttgctggt taatgaaaga aattttgttc ttctctaaaa aaaccactat tttttgcatg
    26881 aaactaaaga atacgccttt cttttttcaa taaactttag taaaataaat cattgagagc
    26941 aattcggaaa tagaaaggag agatttatat ggtatcaaca ggtattgtcg tacttattgc
    27001 tattattgct ttgctaatcg gcgcagtagg tggctttttc ctagcgcgta aatatatgaa
    27061 agactattta gaaaaaaatc ctcccgttaa tgaggacatg ttgcgatcaa tgatgatgtc
    27121 aatggggcaa aaaccatctg agaagaaaat tcgccagatg atgcagcaaa tgaagaacca
    27181 agggaaaaaa taggttctga cccaaagact ttttgcgggc tgattttttc agtccgtttt
    27241 ttatttcgta atttgttaga ctattcagac tattcagcaa aaaagacaag cacagacaat
    27301 cctatgctct tgataaagac aaaggaggag taaaatgtcg atttttagaa aattaggttg
    27361 gttttttcga caggaaaaga aacattattt aattgggatt ttctccctat tcgcagtggc
    27421 cttggtacag ttagctcctc caaaagtgat tgggatcatc attgatgaga tcgccgataa
    27481 aaatttatca ataaagatca tttcctggtg gatcttatta ttgatccttg cagctctctt
    27541 acaatatctt tttcgttata tctggcggac gaatatttgg ggaagtgcag ctcggttgga
    27601 gaaagaactt cggcagcagc tattcaaaca ttttacagaa atggacaatc tcttttacca
    27661 aaaatatcgg actggagatt tgatggctca tgcaacgaat gatttgaatg caatccaaaa
    27721 tgtagcagga gctggtatct tgacctttgc agattcagtg atcacgggcg gaacaacgat
    27781 cattgcgatg attttgttta ttgattggcg cttaacactg attgcgctga ttcctctgcc
    27841 tttactagcc gttacttcac gagtgctggg gtcaaaactc cacgatgctt ttcgtgattc
    27901 gcaagaagct ttttctagta tcaatgataa gacacaagaa agtattactg ggatcaaagt
    27961 cattaaaaca tttggacaag aaaaagaaga tctcgcggat tttgaagaaa agattgaaga
    28021 tgcaattatt aaaaacaaac gagtcaattt tttagactcc ttatttgatc cattcattac
    28081 cttgattatc ggtctgtctt atgttgcaac aattatttta ggtggaaagt atgtcttgga
    28141 aggcacgatc tcaatcgggc agatggtctc atttattagc tatatcggta tgcttgtttg
    28201 gccgatgttt gcgattggtc gattgttcaa cgtattggaa agaggaaatg cttcttatga
    28261 tcgcgtcaat gaacttttgc atgaaaagac gcatatcgtg gaacaactgg gtgcagtgca
    28321 gactccggca aaaggcgagc tgaatgtagc tatttcctct tttaactatc cgaaagaaga
    28381 atcaccagca ttagaacaaa tcaaatttgc gatccaagaa ggagaaacat taggtattgt
    28441 tgggaaaact ggtgcgggaa aaacgacaat catcaaatta ctgatgcgtg aatacgatga
    28501 ttatcaagga aaaattcaat ttggcggatg ttcgatcaaa gaatattcat tgaatgcttt
    28561 attaggatca atcggctatg tgcctcaaga tcacttcttg ttttcgatga ccattcgaga
    28621 taatatccgt ttttctaatc caaaactttc agaagaagaa gtagagcatg cggcttcttt
    28681 agcatttatc aacaatgaaa tcaaggaatt accaaaaggt tatgatacct tagttggaga
    28741 acgtggagtc tctttatctg gcggacagaa acaaaggatt tcgattgctc gagcattgat
    28801 caaaaatcct gaattgctga tcttagatga tgcactttct gcagtagatg ccaaaacaga
    28861 agaagctatc ttgcataatt taaaagaaat aagaaaagag aaaacaacca tcattgcagc
    28921 tcaccgttta agcagcgtga tgcatgcaaa agaaatcatt gttgtcgatc aagggaaaat
    28981 cattgaacga ggaacccatc atgagctgct tgcattaggc ggctggtatg aacgaatgtg
    29041 ggagaaacag aaattagaag cgaagataga aggaggcgag gcctgatgga tgaaaattat
    29101 caatcggaat ggacaaaatc gattccactt aaagaacaga agaagatcat caaacgactg
    29161 atgaagttcg ccaaaccttt tagaagaacg ttcatcgttg ctatcttatt tgcgtttgcc
    29221 ctgtctgtga tcaatgtcct attgccaagg atcatccaaa cttttatgga tgatcatctg
    29281 gctaaacagt cggctacgac acaagttatt ttgttttttg ctggtatgta cttgtttgga
    29341 gtcatagtca aaagtatcat ttggtttttc caatggtatt tgtattccat ggcttcattg
    29401 aagacctatc agtatgttcg ggtaagatta tttgaaaagc tgcatacact aggtatgcgt
    29461 tattttgatc agacaccggc aggatcgact gtttctcgag tgacaaatga cacagaaacg
    29521 ctatttgaat tttggtatgt ctttttgatg gtattgactg ggatctttgc agtcgtttct
    29581 tccttcattg ccatgtttca aatcaatgga gaaattgcct tgtggacttt ggtgttcttg
    29641 ccgattttag gaatcgtcat ctggtattac cagaaattca gttctcgtat ttaccggaat
    29701 atgcgggaaa aattaagtca gctgaacacg aaattgaatg aatcgatttc cggcatgcgt
    29761 attatccagc agtttcgcca agaagctcgt ttagctaaag aatttgaaca agtgaacaac
    29821 gagtatttag acacgcgcta tgcgatgatc aaaacaaatt cgattctgtt aagtccgatc
    29881 atcaattttc tatatgcatt ggcgattgcg ttggcgttga ctttgtttgg gatcgatgcg
    29941 ctgcattctc ccgtagaagt tggactgatc tatgcattta cgacctatgt ccagggattt
    30001 tttaatccaa tgtctcaaat gatggacttt ttgagcacct ttacagatgg aatggttgcc
    30061 ggtagtcgta ttttgaaaat catggataca gaagaatatg caccgcaaca aaatcctgga
    30121 gcagatcaag cgattacttc aggtaagatc gagtttcgca atgtaagctt ttcttatgat
    30181 ggagagcaca atgtattgaa caatatctct tttgtcgcta atccgggaga gaccgttgca
    30241 ttagtggggc acaccggaag cggaaaaagc tcgatcatca acgtattgat gcggttttac
    30301 gaattttatg aaggccagat cttgattgat gatcatgaca ttcgagaata tccaatggaa
    30361 gagttacgta agaaaatggg attggtcttg caagatgcct tcttgtttta tggagatatc
    30421 gcaggaaata tccggatgat gaatccaact atcacagacg aacagattcg ccatgcagct
    30481 gagtttgttc aagcaaacaa gttcatcgat gaattaccaa aaggatatca ctcaaaagtg
    30541 atcgaacacg gtgccagcta ttctagcgga caacgacagc tgatcacttt tgcgcgaaca
    30601 atcgtgacag atcctaaaat actagtattg gatgaagcga cagcaaatat cgatactgaa
    30661 acagaaggat tgatccaaga aggattgaca aaaatgcgac aaggacggac aacgattgcg
    30721 attgcccatc ggctgtccac gattcgggat gcagaattga ttttagtttt agacaaaggt
    30781 catatagtag aacgtgggaa tcatgaaaca cttctagcgc aaaatggttt gtatgcagat
    30841 atgtacaaac tgcaaagcag tggtgtgtaa aaagtggttg tgacagggct ccgttcagct
    30901 ttaggtgata agaaaaaaat tgtaaaaaag gctttccaga tttttgcata aatttggctt
    30961 atcaccgata agctggtact ggaacaccgt atattagaag ttgggacagt agcatagtag
    31021 cattttgacc taagcgctag agtgaaaata aaacagagct tcccagattc ttcatctgtg
    31081 agcgttagtg tcgtaattac cagatttaaa aaaaatcacg acagctagtc agaagtgccc
    31141 aatagccgct aagaaagcgt tgacaaaagt gcttgctttc gataatataa agaaaacgat
    31201 acaacttgga tagtgattgc ctgatgcaag ctaaacctga tgagtctccc atggttccat
    31261 ggacggcttt ttgggttttt ctttttgttt tggatacagc cctatatatc atggaaagga
    31321 gtaaaacatg ctgattgaga aagtactgaa taacaacgtc gtaataacca gggatgaaag
    31381 aaatcaggaa atgatcgtga tgggaaaagg tttggcattc aaaaagaaag tgggtgaccc
    31441 gatttttgac tcatgcatcg acaaaaaatt tcagttgaca aatgacggac tttcacaaca
    31501 gttccaagaa ttggcacaag cgattcctct tgagtactta gaaatttctt gtgaaatcat
    31561 tgaatataca aaagaggctc tacaagtcca gttgaatgat tcggtgtata ttgcattgac
    31621 ggatcatttg tatacggcta tcgaacgtca caaaatggga atatttgtac caaatgtatt
    31681 gctgtatgat atcaaacaac tatttcctaa agagtatgcc atcgggaaaa aaacagtgaa
    31741 gaaaatctcg gataaatacc acatcaagtt atcagaagat gaagccggat ttatcgcatt
    31801 gcatttagtc aatgcacaag gcattcaaag ccaacaagac aatacctacc tgtttactac
    31861 aacaatacag gatattctaa atatcgtccg ctattactat aagattacat ttgatgaaga
    31921 ttcagtccat ttttttcgat tcgtcacaca cctacgtttt tttctgacac gcgtcctaga
    31981 tggagaaaaa tcagaagtgg gagaagtttc tgaggaattg taccaggtta ttcaaaaaaa
    32041 atataaggat acgtttggtt gcgttgagaa aatagcagac tttttagccg agatattcaa
    32101 ctaccagatg tccacggacg aaaaaatgta tttaacgatc catattgcgc gtttagtgca
    32161 tgagaatcgt tgtaaataaa taaaaaaagg aggataaatt aacaagaacg catgaaataa
    32221 gggtagtgac attcagttgg ctaaaccttc cactaataaa ttggagggaa tagaaatggg
    32281 aaaatatcaa gaattagcga gcaaaattgt agaaaatgtc ggcgggaagg aaaatatcaa
    32341 tggtttgaca cattgtatca caaggcttcg tttcaaatta aaaaacgaag aaaaagcaaa
    32401 tgatgagatc ttgaaaaata tggacggtgt tgtgacggta atgcgagcgg gaggacagta
    32461 ccaagttgtc atcgggaatc atgtgccagt cgtgtttgaa gaggttataa aagcaggaaa
    32521 ccttactttt gatgaggctg tttcaacaga aaaaatgaga ccgtttgata tgcttattga
    32581 tggaatatcg ggctgtttcc agccattcct tgctattcta gctgctggtg ggatgattcg
    32641 tggactgaca gcattacttg tcttcttagg cgcatttgac cgcggttctg gcacatttgt
    32701 tatgtttgat aatatcggtg attctgtatt ccaatttatg cctgttatta tcggtttaac
    32761 agctgcccgt aaatttaaag taaatgaatt cgtagggatg ttgcttgggg cagcattaat
    32821 gaatcctagc ttgtcgctgg aagctttgag tggtgcagca gaagcaccac tgactaccat
    32881 attttctggc actatttttg aagcacctat ttatcaaaca gtattcggca ttccctggat
    32941 tgcgcgtaac tacgcttctt ctgtcattcc cattatcttt attgtgttgt tagctagcca
    33001 aattcagaaa ccaattaaaa agttagtacc tgagatgatc gcgaatttct tcgttccatt
    33061 cttcaccgtt cttattacaa tgcccttagg ttttttactc gttggaccag cattcacatt
    33121 cgcaactgat attttaatgg ctggatttga aacactttta gcactttcgc cagttattta
    33181 tggagcaatc gtaggcttct tctggcaaat tctagtgatg tttggtctcc attgggcaat
    33241 cgtaccaatg ggattgatgc aattttctgt gaatggttgg caaaatatca tgacacctgt
    33301 tgcagtagtg tcttttggac aaactgcagc acttactgca ctctacttta agcttagaaa
    33361 cccaaaagac aaagcaatcg caataccagc cattgtttct ggtattgtgg ggattacaga
    33421 gccagctatt tatgggttta cattgccacg taaaaaaata tttattttta cctgtgtcgg
    33481 tggtgcgtta gggggcgcgt atagtggatt aatgaattta acttcttgga atccaggtgg
    33541 attaggcatc tttacaattc ccaactatat tagaccagat ggtgatttaa cggatgtgat
    33601 taatgtattg attggaatcg ccattgcgat ggtggtatcc tttgcgctga cttttttctt
    33661 ttggaaggag gaagcaggtg aaacagatga tagacagaaa agatcaggta aagaaattgt
    33721 aaaaacaccg atacaaggac aaatcgctcc actgaatgca gcaaaggatg cagcttttgc
    33781 acaaggaaca ctaggtcgag gaatcttgat ctaccctgaa aaaggagaag tacgtgcccc
    33841 ttttgacgga acagtcatga ccctgttccc gacgaaacat gcaatcggaa tggtttctga
    33901 agcaggtctg gaattgctga ttcatgtcgg attggatact gttcagttgg aagggaaata
    33961 ttttgaaagc ttggtgcagc aaggagaaag agtgaaacaa ggcgatctgt tgctccgctt
    34021 cgacaaaaag aaaatcgaag aggaaggata cagtttagaa acacctgtga tcgtcaccaa
    34081 ttacacggat tatttggata ttttggaaaa tcaaggggag acggtcgggc cagacgatgc
    34141 acttatcacc gcactgacct gaacggttag gtgaaagaat ggactaggct taattattct
    34201 ttttagtcca cttctttatt ttcaaaattg aaaggctctt tcatgatggc tgagctgata
    34261 gggcgtttat caaatttttg tcctacagaa attagatgga ctaaattctg ttgataattt
    34321 tctgcaaaaa cacaactata taacacgtct agaagataac aaatcgatgt attgatcgta
    34381 aaattaccaa ttttcgaata cagtcgttcg cgtgtcgtaa gtcgcaaagc ggctgtactc
    34441 attgaagata gcgttgaatc accgatactg gtcaaagcta aaattggaac atgattttgt
    34501 ttcaatattt ctgcggtacg aaggatcaca ttgttttcac ccgtataaga aatcagaatc
    34561 ccgcacatat cactcgtgca attgtacgct tcatagaacg attcaccaaa agtggtgaca
    34621 atcgtgacat ccattttgat gcgcttcatt ttcagcatga aatcttgaga aatcaaagta
    34681 ttcgagttac tggcgaaaat cacgattttt tttgcttgaa gcattagttg tttggctttt
    34741 tgcagttggt catgatgaat gagagaaagt gtatcttgaa tcgtcatctg ttctaaagaa
    34801 gccattttat ttgcgatcgt cataataccg tctgtggtgg aaaaaggaag attcgcatct
    34861 acgtcttgaa aattcccttc aagataggct gtttcagcta aaaaagcatt acgaaaactg
    34921 acccagccat caaaacccat tttttttgct acacggatga gtgtggacgg gtggacataa
    34981 catcgctcag caatctcttg gatggtcatt tcgccaagtg ctggagaatc gcttaagaga
    35041 aactgaatca cttcattttc tgaaggagaa aaggagattt ctttgatttt ttcacgtaat
    35101 aacatgtaga taccttcttc ttgttttttt acgtaaatta taactttttt gaaaatgatt
    35161 tgtaaacgga tttatgttat atagcttaat aaagacattt tttgacaaga tatttacaaa
    35221 aatccagtag aaaacactaa cttttgtaaa tgttactgga aagaaacgaa tttctattgt
    35281 ttgttttgtt tacaaaaaag ataataaaag tgtaaaaagt aaaggagtga gaacatggca
    35341 aaaggaatca aaatcgctac gattggtgga ggcagcagtt acacccccga gttgatggaa
    35401 ggatttatca aaagatatga ggaattaccg atacgagaaa tctggctcgt agatgtagaa
    35461 gaaggaaaag aaaagcttga gatcgtcagt cagatgtctc agcgtatgtg ggatgcttct
    35521 ccgtatgaag tcaaaatcta tgcaactctg gatcgggaag aagcattgaa agatgcggat
    35581 tttgttacga ctcagtttcg tgtcggtcaa ttagatgcac gaatcaaaga cgagcggatc
    35641 cctagttatt atgggatgat tgggcaagaa acaaatggtg ctggcgggat attcaaagct
    35701 tttcgtaccg ttccagtggt tttggcaatc gttgaagaca tgaagcgttt atgtccaaat
    35761 gcttggctga tcaatttcgc gaacccaagc gggatggtga cagaagcagt tatcagatat
    35821 ggcaaatggg ataaagtgat aggattatgc aatgtgccag taatggcgat gatgacagaa
    35881 ccaacaatgc ttggcaagaa aaaagaagag ctgatctaca agtttgccgg tctaaatcac
    35941 ttccattggc acaaagtagc agataataaa ggaaatgacc gcacggcaga attgattgat
    36001 cgtttatacg atgaagacaa tggattgccg aaaaatatct ttgatatccc gtttttcaaa
    36061 gaacaattaa aacaaatgaa catgatccct tgtggctacc accgctatta ctaccgtgaa
    36121 gaagaaatgc tggaacatgc tttagaagaa tatcaaacga ttggtacaag agcgcagcaa
    36181 gtgaaagaaa cagaagcaga gctgtttgaa ttatacaaag atccagaatt ggatcataaa
    36241 cctgaacaat tgcaaaaacg aggtggtgct tattattcag atgctgcctg tgaaacgatt
    36301 gcttcgatct atggaaataa agaaacacag atcgtggtat ctacaaagaa tgatggagct
    36361 gttcctgatc tgccggcaga ttgtgtagta gaagtcactg cctatgttgg cgcacaaggc
    36421 gcacgaaatg tagcgtttgg ttcccttcct gctgctgaaa gaggctggtt gcaagtaatg
    36481 aagaatatgg aattgctgac gatcgaagca gctgtgactg gtgattatgg aacagcttta
    36541 caagcgttta cgatcaatcc gcttatacga tcaggaaaga cagcaaaacg gatcatgaat
    36601 gagttgttta ttgcacatca gcagtattta ccgcaattca aggaaacaat cagccggtta
    36661 aaagcagaag gaatcgaagt ccaagatgaa ctggcaagag aattatcaag caatacacat
    36721 gtaatggagg aagtatgatg ggattcagaa aagatttttt atggggcgga gctacagcag
    36781 ccaatcaatg cgagggcggt tatgatgaag gcggacgtgg gttagcgaac gtagatgttg
    36841 tgccaatcgg agaagaccgt tttcctgtca ttactggaaa aaagaaaatg tttgaatttg
    36901 atgaaaatca tttttatcca gcaaaaattg cgatcgatat gtatcatcat tataaggaag
    36961 atattgcttt atttgcagaa atggggttca agacttatcg gatgtccatt gcttggagtc
    37021 gtatttttcc aatgggcgat gaaaaagagc caaatgaatc tggtttgaaa ttttatgagg
    37081 atgtctttaa agaatgtcaa aagtacggga tcgagccgct tgtgacgatt acacattttg
    37141 attgtccgat gcatttgatc aaagaatatg gtgcgtggcg ttccagagaa ctcgttggtt
    37201 tttatgaaaa tctgtgccga gtcatcttca atcgctataa aggacttgtc aaatattggt
    37261 tgacattcaa tgagatcaat atgatccttc atgcaccatt catgggcgca gggctgtatt
    37321 ttgaagaagg agaaaatgaa gaacaaatca aatatcaagc ggcacatcat gagttggttg
    37381 caagtgccat cgcaacgaag attgctcatg aagtagatcc ggagaacaaa gtaggctgta
    37441 tgctggcagc aggagcatat tatccataca cttgcaatcc tgaagatgtt tgggcttcta
    37501 gaaaatcaga tcgagaaaat tatttcttca ttgatgtcca gtcacgagga gaatatcctg
    37561 cttatgcatt gaaagaaatg gaacgaaatg gcattcagat caaaatggaa cctggggatg
    37621 ccgcattgct gaaagaacat actgttgatt ttatctcctt ttcttattat tcttctcgag
    37681 tttcgactac tgacaacgaa ctcttggaac agactgcagg aaatatcttt gcttctgtca
    37741 aaaatccata tctggaagca agtgaatggg gttggcaaat tgatccatta ggcttgagaa
    37801 taacgatgaa tgatatttat gatcgttatc aaaaaccact atttattgta gaaaacggct
    37861 taggtgcagt cgatacgccc gatgagaatg gttatgtgga agatgactat cgaatcgact
    37921 atctggcagc acatatccag gcaatgaaag atgcagtaga attagatgga gtcgatctat
    37981 taggctatac gacttgggga tgtattgatt tagtatcagc tggtacaggt gagatgaaga
    38041 aaaggtacgg attcatttat gtcgatcgtg acaacgaagg aaatggcaca ttagcccgtt
    38101 cgaagaagaa atcattcaac tggtataaaa aagtaattga ttcaaatgga gaaaatcttt
    38161 cgaatgattg atcaatgatt tataaaagtc tattgttttt cagcggattt ttcgagtata
    38221 ataaagctat tcgagaaacg caagcagaac aatagacttt ttttcgcatt ggctgtaaag
    38281 tatgcttact tgattaagta aaggagaatc tacatatgta tgatgtaatc gttattggcg
    38341 caggtcctgc tgggatgact gctgctttat atgcttcacg ttcaaactta tccgtattga
    38401 tgatcgaaca aggcgcccct ggcggccaaa tgaacaatac ggcagaaatc gaaaactatc
    38461 ctggtttcga ttcaataatg ggtcctgatc tagcttataa gatgtatgaa ggtgtttcaa
    38521 gatttgggac agaaaatgct tatggaatcg tgcaagatat caaggatcac ggcagccaca
    38581 aagaagttat ttgtgaagat aaaacttacg aaggaaaaac agtcattatc gcaacaggct
    38641 gtatccaccg taaattaggc gtacctggcg aggaagaatt tgctggacgt ggcgtttctt
    38701 actgtgcagt ttgtgatggt gcgtttttcc gtaacaaacg tctagtagtg atcggaggag
    38761 gagactcagc agtagaagaa gccatctatt tgacacaatt tgcttctgaa gtagtcatcg
    38821 tccaccgtag agatgaatta cgtgcacaaa agatcatcca agaccgtgca tttgcgaatg
    38881 aaaaaatttc ctttatgtgg gatacagtcg ttgacgaaat cgttgggaat gaaatggtag
    38941 tgacaggtgt gaaagcacgt aatgtcaaaa ccggcaatga gtttgatttg gcagcagacg
    39001 gagtattcat ctatgttgga ctggatccat taactgcacc atttagagaa gcagggttga
    39061 cgaacgaagc tggctggatt ccaacagaca acgaaatgaa gacgaatata ccaggcgttt
    39121 ttgccatcgg agatgttcgt gaaaaagatt tgcgacaaat cactactgct gttggtgatg
    39181 gtgggatcgc tggacaacaa gtgtataaat acttggaatc tttagaagaa acaactgcat
    39241 aagtttaaaa agagtggaag aacggtttaa ttgttctttt actctttttt ttcgcgtgaa
    39301 atctactgaa tccgatttat gcgaatactt gcaaccgtgc ttgataaaag aatcctttct
    39361 tgatttaagc gttttttggt cctcatactt tcatatctaa taagtgaatg ctatacttat
    39421 taagaaccat atttcagaaa gaggtgttat tttcatgtct tgggaacaag tgtatgaaca
    39481 atgggtacat gaagaaaatt tagaagaaaa cttaaaaaaa caattaaatg atctgggtga
    39541 agatcctgaa aaacttgaag atgcttttta tgcaccgttg gaattcggta ctgcaggcat
    39601 gcggggaatc ttagggcctg ggatcaatcg aatgaacatc tatacggtaa gacaagcaac
    39661 agaaggactt gcacgtttca tggatacaca aggcgaagaa acaaaacgcc gaggtgtcgc
    39721 tatcgcttat gactcacgcc atcaatcacc agaatttgcc atggaagcag ccaaaacatt
    39781 agcacatcac aatatcccat cttatgtatt cgaaagtcta cgtccaacac cagagctttc
    39841 ttttgcagtc cgtcatttga agacgtttgc gggaatcatg gtaaccgcat cccacaatcc
    39901 agcagcttac aacggatata aagtctacgg agaagatggg ggacaaatgc ctcctgcaga
    39961 cgcagatgca ttgacgaaat atgtccgtga agtcagcaat ccgttaaaag ttgaagtatt
    40021 atctgacgaa gaagctgaac atagcggatt gatcacgatc atcggagaag aagtggatgc
    40081 cgcttatcta gaagaaatca aagcagtaac gattgatcat gaattggtgg aaacaatggg
    40141 gaaagatttg aaacttgtgt acacaccact tcacggaaca ggaaaaatgt tgggcgaacg
    40201 tgcgttgaaa caagctggat tcgaacaatt cgtactagtt ccagaacaag ctgtcgcaga
    40261 cccagatttc actacagtca aatcaccaaa tccagaagaa cactctgctt ttgagtatgc
    40321 gatacgactt ggcgagaaag aaggcgctga tttgctgatt gcaacagatc ctgatgcaga
    40381 ccgtttaggt gcagccgttc gtttgccaaa tggctcctat gaagtattga ccggaaacca
    40441 aatcggagca ctgtttgctc aatatatttt ggaagcacac caatcgcgag gcactttacc
    40501 tgaaaacgca gcggtattga aatcgatcgt ttctagcgaa ttacctacag caattgcgga
    40561 acactatggg gctaccatgt tcaatgtatt gacaggattc aaattcattg ctgaaaaaat
    40621 tcaacaattt gaagaagatc attcccatac ttttatgttc ggattcgaag aaagttacgg
    40681 ttatttagtt aaacctttcg ttcgcgacaa agacgcgatc caagcattgc tcttattagc
    40741 agaagtagca gcttactata aaaaacaagg caaaacgttg tatgatggct tgcaaacgat
    40801 ttttgaaacc tatggctact acgcagaaaa aacgatttct gtgacaatga gcggacaaga
    40861 aggttctgcg aaaatctctg ctttgatgga aaaattccgt gaagaagcac caacagaatt
    40921 tgccggagca aaagtcatcc aaacagaaga cttcaaagag ttgacgagaa cagaccgtga
    40981 aggaaacgta gaaaaactaa cgacaccgcc atctgacgta ttgaagtata cgctggaaga
    41041 aaatggctgg atcgctatcc gtccttcagg aactgagccg aaaatcaaat tttatatcgg
    41101 tgtaaaagga aactcttcag aagacgcagc tgaaaaagta gccgcttatg aaacgattat
    41161 ccaaaagatg acagaagaat aaaaaaactt gagactgatg gaaaaagtgg taaactttag
    41221 aagtcagtct tttttcaagt tggaggtgaa tggattgcca gacacgcaaa aaacaaaagt
    41281 agagaaagtc agccaactat tcaaaatgtt gagtgacccc actcgtctca aaattctgct
    41341 gtatctgaaa gacggggaac aaaatgtgac agcaatcatc caagcagtgg aaatggaaca
    41401 atctgctgta tcgcatcaac tgcgtttatt aagagaaaac catgtcgtca agtcccatcg
    41461 tgagggaaaa gcgattttgt atagtcttga tgattctcac gtactggata ttttgaacca
    41521 gacactcaaa catgtggaac atcaataacg ataggtgcaa atagagacaa actggactgt
    41581 gtcaacgaat cttcttcgct gacacagtcc agttttttta aagaaaaatt gttagtctgt
    41641 ttcttcggtg gtttcagttc cataataact atggtcttct aggtctaaag cattcaaaat
    41701 aagcgaagct gtttcttcaa tagataaaga agcgacattg attactacgc agcccaattt
    41761 ttcataaaga tcattcgcaa aatcgagttc agctcgtatt ttttcgatat cggaataagc
    41821 agtatcagga tttaatccgt aagagcgcat ccgttcttta cggatattgt ttaaaatatc
    41881 tgggttattc gtcagtccca cgattttttt aggatcgatc tcccaaagct gtttgggaat
    41941 atgtgcttgt gggatcaaag gtagattggc aacttttaaa tttttgttag ctaaaaacaa
    42001 gctcaaaggc gttttggaag ttcgggatac gcctagcaaa acgacatctg cttctagaaa
    42061 cccacgagga tctttcccgt catcgtattt tacagcaaat tccattgctt tgatccgttt
    42121 gaaatagttc tcattcaata aatgaagggc gccaggttgc cgaatgggct tgataccagt
    42181 taagcgctcg atttctgata tcggcggagt catcacatca aaactaaata attgatgttc
    42241 ttcacaaaaa gaacgcgtca tctcgatcaa ttcttgattg atcaatgtgt gcaggacaag
    42301 agctttttct tctagtgcat cttgcagtgc ctgcatcaat gttttctcat ctgtcacaaa
    42361 tgttctgcgg aataaattga actcaacgct aggatattgg gccatagtgg cttgcgctag
    42421 ttttgtcgca gtttctccag cagagtcgga gatgacaaaa aaagtaacga tttctgtaga
    42481 atcggaagac atggataaaa cctcacttgc atttttttta tgtttattat accatactct
    42541 agaatgtgta cttcgtaatc attttgattt ggaggaataa gtcatgaaaa aacagacgtt
    42601 gatcgaacaa tcactagaaa cattgaaaaa taacggtttt aaatatacta aaaaaagaga
    42661 agcattgtta acttatttag tgaagcgcaa tcgctacgta tccgctaaag aagtttttga
    42721 ctatatgaat caggaattca aaggagtaag ttacgatacg atttatcgaa atctccatga
    42781 ttttgcagaa atcgatttac tggaagaaac cgatttaaat ggagagatga agtttcgttt
    42841 tcattgctgt caaggggaaa tcggccatca ccatcacttt atctgtacgg tgtgcggaac
    42901 aacgaaagaa atccatatgt gtccaatgaa ttatttcgaa gaacagctcg gtggatgtac
    42961 gatcgaaggg catagattcg agattttcgg aagatgtgaa aattgtcaat aaggatttaa
    43021 ataaaataac atttgataat tttaaaaaaa agcaagattt ccttgacggt caaaacagca
    43081 ttagatataa tatttacagg acagtcttgt tttttgagat atatttcaat aacaattacg
    43141 gttacttttt aagctcggag ggagggaatt aacatgtcaa aaacagtcgt tcgcaaaaac
    43201 gaatcacttg acgatgctct tcgtcgcttc aaacgttccg tgtcaaaagc gggtacttta
    43261 caagaatctc gtaaacgtga attctacgaa aaaccaagtg taagacgcaa gaaaaaatct
    43321 gaagcagcta gaaaacgcaa aaaattctag ttctgtgatg aattggagtt ggtagtgtgt
    43381 cactactaag tagattaaac gatgacatga aaacagcgat gaaagcgaaa gataaggaat
    43441 ctttacaagt catccgaatg atcaagtcat ctatacaaaa cgagcagatt aaagaaggtc
    43501 acgacttgac agaagaagaa gaattaacgg tgttgtctcg cgaaatgaaa cagcgacgtg
    43561 attctttgca tgagtttgaa gaagcaggac gtgacgattt agctgaaaaa gtaaaaagtg
    43621 aaattgtgat agtcgaaaaa tacatgccgg aacaactttc cgacgaagaa attcgacaac
    43681 ttgttcaaga agcaatcacg caaactggtg cttcatcaat gaaagaattt ggcaaagtca
    43741 tgggtgcgat catgcctaaa gtcaaaggaa aagcagatgg aaaccaagta aatgccattg
    43801 tgaaagaact attacaatct taattttatc atttaaactg cggacaatca ttgtccgcag
    43861 tttttttgtg ctcgtaaaaa agagatctaa aaaatagcta gacgaaagaa taggattctt
    43921 tcatctagct gtttttttcc tgtttaatat ttcttatgtt aaattgtgtt tgatctggtt
    43981 attcttctgg tagttcattt gcttcttgtt tataccctga taggcgatag gcgtaataga
    44041 agagtaagct gccagcatac ccaagtaacg ttgggaccat ccagccaagt cccaatgcag
    44101 caaaaggaac gtgatgatga taaaattcga gcatgcttgc tacaactctt tgttgactca
    44161 ctaaagcagg cgaatttgcc agcatatcca atacggcggg aacagcagca aacaacatcg
    44221 ttacttgata gacaaatggt gtcttttgga aaaattttgc tgttaaggaa agcaaaatca
    44281 acgcaagcga caatggatac aaaagcatca atactggtaa agaccattgg atgatattgt
    44341 ccaaaccagc atttgcaacg acaaaagaga cgaaagtcgt taaccgcagc catgtcatat
    44401 aactgacttt agggaacagt ttatggaaat cttgtgcaaa agaaacaacg agtcccatag
    44461 cggtagtgaa gacacctaat gtgaccatca ctcctaagaa gctagcgccg aagttaccta
    44521 aataaaaatt agtgatctga gaaagtgcag ttccgccatt ttctgataaa gacatcttat
    44581 tcaaactcat cgcaccgaga agaacaagac caaaatagat catgacttct agcgcaacgc
    44641 tcaggctacc agcttttgct gttaattctg tgactttttt atctttgaaa ccaaggtcac
    44701 ggactgcatg gacaaaagtg acacttaagg caagcaaggc tactgcatca accgtgttat
    44761 aaccttctag gacaccattt gttaaagcgt ttgtttggta agtatctgca gcagattgat
    44821 ttagatttcc cattgggtgg aataaagaaa cgacaaaaat gattgctaat aatgcaagaa
    44881 acaaggagtt tagatacttt ccgacgtatt tgaccaaccg tgtgggatgg acagtaagga
    44941 aataagcaag taaaaagaaa agagcagaga ataaaaacat acctaatgaa ttatattttt
    45001 caggcaaaaa tggtttagca gccatttcaa aagcagtagc agctgtccgt ggtgtaccga
    45061 aaaatggtcc gatcgtcaaa tgaacaagga ttaagaacaa ggcagcatac cattttccga
    45121 caggtttagc taagtcatac agaccatcac tttttgtcac tactacagct aagatagcta
    45181 gtaatgggaa aagagcgcct gagatggcaa atcctacgcc agcactgacc cagtttgcgc
    45241 cagccatttg acctaagtgg acaggaaaga ttagattacc tgacccgaaa aacatcccga
    45301 agataagtga actgaccatc aatagttgtt tccatgaata agtttttgtt tcttccataa
    45361 atttttcctc caataattat cattttgatt gacgatataa acgttgcagc aattagtaat
    45421 gccactaata tcagattcca tgaaaaccac caccttaaaa tataaaaaaa agcccttttc
    45481 cacttgggaa aagggctcta gattctagaa cggtaccacc ttttttcgct taaaaaagct
    45541 tcttcattca cggacgcttt ttgataaagt tatccgctag cctgataatg gaggcagcca
    45601 caatgatcta cgttttcgac attgactcgg aaatgatgtt cgtctattcg atttattgtc
    45661 atttctcact tacatgactc actgggaata aatcgttgaa tagcctactg ttttcctcga
    45721 cgctttgctg tatgtttatt tgttgacgta ataatacacc tgtttttttt gaaatgcaag
    45781 aatattttaa ctattttgtt ttcttttttt gaaacaagaa aaatacctag agaatacctc
    45841 tgaatgaaac ggaatatttt gttctccact ttcatataac ttacattctc agattctttt
    45901 tatcaaaacg agacctttag cgaatggaaa cagctatttt ttaacgtttc ttggtacgta
    45961 tggttaaacg actcttttac aaccttttct tatttgctat atagtttctt ctgagtatgg
    46021 taaaatagga aagaatgaat cgaaaaaaag gggatgtcta tttttgacgg aagagtctag
    46081 ttctttagag attagattga cagctgctga tgatgtcagc atgcttttag gtgcacacga
    46141 caagcatata aaactgatcg aggaaacaac ggaaacaacc atccatacac gtggagaaat
    46201 cattcagatc attggtgaac aatcccagat ttccttggct gcctcagtca ttcggacatt
    46261 acaggaattg atcaaacgag gaatccacgt aagtacacca gatgtcgtga cggcattgaa
    46321 aatggggcaa aaaggtacat tagattattt tgttgagatg tatgaggaag agatcgtcaa
    46381 agaccgtaat ggaaaaccta tacgggtaaa aaacagcggt caaaagaaat acgttgaatc
    46441 ggtagccaaa catgacatcg tatttggtgt agggccagcc ggaacaggga aaacgtttct
    46501 tgccgtagta ttagcaattg ctgccctaaa aaaaggcgaa gtgcaaaaaa tcattttgac
    46561 gcggcccgct gtagaggcag gggaaaacct aggctttcta cccggggatc tgaaagaaaa
    46621 agtggatcct tatctgcggc ctgtttatga tgctttatac caaatttttg gattggatca
    46681 tacgaaccga ttgatggaac gaggcgtaat cgaaatcgca ccattagctt acatgcgggg
    46741 gcggacattg gatgatgcat tcgttatctt ggacgaagca caaaacacga cagtcgctca
    46801 gatgaaaatg ttcttgaccc gtctcggtta tcaatcaaaa atgattgtca atggggatac
    46861 aagtcagata gacttgcctc gagggacgac aagtggtctt gttcatgcag aacgaacact
    46921 aaagcaaatc aaaaaaatcg attttgttaa ttttgaagca agtgacgttg ttcggcaccc
    46981 tgtagttgcc gaaatcatca aagcttatga aaaggcggat cttcatcaag aataagcttt
    47041 gcttaggagg ataagcacat gttgaataaa acactgcaga aactacaaga aaaactcgga
    47101 aaggcagcat tgcctttcct tctgttcttg ttttttatca ttgtctgcgg cgttacattt
    47161 agtagtgtca aacaaaaggc caatgatttc agagaaggcc aagtagcaga agagagtatc
    47221 cgtgcgaata aaacgatcga gaacacggaa gaaaccgaac aaagaagaaa actggcagca
    47281 gaagcagtga ctccagaata tacttatcaa aaagatctgg cagatgacca gaacaatcgg
    47341 atcaagcaat tattcgaatt gatcgataag acgaatgata ccatcaacaa atcttataat
    47401 gacaaggtag ataaggcgaa ggaagatgaa aatatcccga aacctactac agaagagcgg
    47461 attgctacac tgaagaaaaa ttttgaaaac gtgaatgcag aaaacgttgc gttttaccaa
    47521 aaactgccga acaattttta ttcgacgata tttgaaatga ctgaaacgga aattcacacg
    47581 gttagggatg aaagtttgaa gctcattgac gaacagatga gtaaacaagt tcgtgaaagc
    47641 gaattggaag cttttaaaca agaagcagaa gatcagattc agtatttgaa tgtcacaaca
    47701 gagcagcaac aaatgattcg ctacttagtg gatcaaggca ttgtagtcaa tgatgtattg
    47761 aatgagaaaa agacagaaga attaaaacaa tctgcacgag aagctgtaca accagtgatg
    47821 atcttccaag gagaaatcat tgttcgcgaa ggaaatcaaa ttgatgcttc agcgatgaaa
    47881 aaattggaat tactaggatt gacgaatcaa acgacttcga ttttcccact cattgccatg
    47941 gttttagctg ttttgcttca aatcggcgta ctgatttata attcacttca attccaaaat
    48001 gcaggagaaa gaacaaaata cgtgcttttc tatgtgacag ctatgtcagt cagcatagtg
    48061 ctgatgaaat ttttccaatt attccaaacg gaacaagcta cttatatccc gctgttttat
    48121 cccgctgctt ttgcaccact tgttttaagc tttttcttga accgaagagc agggatcatg
    48181 gctggtattt tccaagcagt atctgcactt ttcatttttt atgattcgat tggcacgaac
    48241 tttctaacga ttatcttgat gtcttatgtt ttctctgggc tcatggcaac gattgtcaga
    48301 cgcaaacgga tctcagaaca aggattatct gctgccatgt gggtcattat ttttcctgtg
    48361 atgatggatg tcattttgat cgtctatcaa ggaatgagct ttggtgatgc aacgacttgg
    48421 ttaatgcttg tctgcgggtt cactggtgca ctcttctcat tcttgctgac gatcggtcta
    48481 cacccatata ttgaattgat ggtcaatgat gacagtgtaa ttgtattaaa tgaactcagc
    48541 aatccaaatc atcctttatt gaaacagttg ctggaagaag cgccaggtac ttatcatcat
    48601 agtatgatgg tagctaatct aagtgctaac gctgtagcag aaatcggcgg acgttctttg
    48661 ctaactcgag tagcttgcta ttatcatgat atcggcaaga tcaaacatgc tagctttttc
    48721 gttgagaact tgccttcagg agcggaaaac ccgcacaatt tcttattgcc agaagacagt
    48781 aaacatatta tctttggaca tgtgacagat ggagccaaaa tattggaaga ttataatatg
    48841 ccgcaaatgg tgatcgatat ttgcaaacag catcatggaa ccacgctaat gcgttatttc
    48901 tacatcaaag cgaaagaacg caatccggaa gtaacagaag agcaattccg ttatcctgga
    48961 ccaaaaccgc aaagtcgtga agcagggatc gtcaatattg ctgacagttg tgaggctgca
    49021 gtacgggcaa tggatcatcc gacgagcgaa aaaatcgaaa gttttgtcca taatcttatc
    49081 gaagagcgta tttccgatgg tcaattagac gatagtggac tgaccttgaa agaaatccga
    49141 aaagtggaaa aatcattgat cagcggttta agtagcacct tccattctcg gatcaaatat
    49201 cctaaaatga aaacagaagt tgagaagata aaggaagaac aagaagaata gaaagaagcg
    49261 atgtataatg gatattacct ttatggatga aacaaaccaa gtctcagaag agaaaatgaa
    49321 agaaatcgat gacttgctgc aatttgcagc atcttattta aagctgccag aggaaacaga
    49381 aatgtctgtt actttcatgg acaatgcggc aatccaagta atcaatcgtg attaccgtgg
    49441 aaaagatgca ccgacagacg tcatcagttt tgctctggaa gaagaaggcg aagacgaaat
    49501 cccagtgatt tttgaagatg gagagaatcc tttgcctcgt gtactaggag acatcatgat
    49561 ttctattgaa cgtgctgctg aacaagcaga agcttacggc cattcatatg atcgggaact
    49621 tggcttttta gcggtacatg gattcttgca tatcaacggg tatgaccata tgacaccaga
    49681 agatgagaaa gaaatgtttg gtttacagaa agagatcttg gatgcctatg gactcaaaag
    49741 ataaaaacgt agagaaaaac aaacatttcc tgatgtctgt ggaatttgct gtccaaggag
    49801 tcaaaaccgt ttttgaggaa gaacgcaata tgaggaaaca tgttgcgttc ggtatccttg
    49861 ctttatttat gggcgtgatt ttccagcttg atcggataga gtggttatgg ctgcttttag
    49921 ctgtttttct cgtttggata gtagagatca tcaatactgt ttttgaaaat gtagtggaca
    49981 tgtttacgga ttttcatttt catccgattg ggaaaaaaat caaagatatg gcagctggag
    50041 cagttttagt gaccgcttgt tttgctgtca tcattgggtt gattttattt gtccctaaaa
    50101 tatatcattt gttgtttaat taaaaaggag aacgtatatg ccagaacata aatcagggtt
    50161 tgtcgcaatc gtcggccgcc cgaatgtagg aaaatccaca ttattgaacc gaatcgtggg
    50221 tcaaaaaatt gccattatga gtgacaaggc acagacaact agaaataaaa tccaaggagt
    50281 atatactaca ccagaagctc agctgatttt tatcgataca ccaggaatcc ataaaccaaa
    50341 gcatcgtcta ggagatttta tggtagaagc agcttacagt gcgttgaaag aagtggatgc
    50401 agtcttattt atgatcagtg ctgatcaaaa acgcggccgg ggagacgatt ttattattga
    50461 acgtctaaaa aacgtgcatt ctccagttta tctgattatc aataaaatcg ataagatcca
    50521 tccagacgag ttgctgggaa tcatcgaaga ttattcgacg cagatgcctt ttgcacaagt
    50581 gattccgatc tctgctacag aaggaaacaa tgtcgaacgc ttaatggatg tattagtcag
    50641 tgaaatgcca gagggcccac aatattttcc agatgatcaa gtgactgatc atcctgaata
    50701 ctttatcgtt tctgaattga tccgtgagaa agtcttgttt ttaacacgag acgaagtgcc
    50761 tcattctgtc gcagtcgttg ttgattcgat gaagcgaaac gagaatgata aaatccatat
    50821 ccaggccacg atcatcgtcg aaagagatag ccaaaaagga atcattatcg gcaaaggcgg
    50881 aaaaatgctg aagcaagtag gaacgaaagc aagaaaggat atcgaaaatc ttttaggaga
    50941 caaagtattt ctagaacttt gggtcaaagt ccaaaaagac tggcgagaca aaaaagtcta
    51001 tctgcaagac tttggctacc gaaaagacga atactgatat tctgaacttc ttataggtta
    51061 agtatagaaa taaactggat aaaaatccgc acgttgagaa aaacggcgga agatcgaaac
    51121 ataaataatc tggatcggca gaatctgctt ttccagattt attttttagg agggagaata
    51181 tgagccagct tgcagaatcg aaaggcttga ttttatctag ccgtaattac aaagaaaaag
    51241 ataaattagt caaaatcttt acggaatctt ctggcaaaat gatgttttat atcaaaggaa
    51301 tccatcggca aaatcagcca ttagctccgg ctttgctccc ctttaccgaa gcagtctata
    51361 tcggtaattt tcgaagtgaa ggtttgtcgt ttttaagcag tgtcaaagac gtccatgcgt
    51421 ttcggaacat ccaagaagat atctttttga gcggttatgg tacctatttg ctaaatctag
    51481 tagatgcagc aatcgaagat catcaatatg acccgcattt attccaattt acgcaacaag
    51541 ctctgcagcg gatggatcaa ggagatgatg cagaaatcat cacgaatatc tttgaagttc
    51601 aaatactgca acgcttcgga atcgcgccaa tttggacgca ctgtgtcgta tgcggggaaa
    51661 caaaaggaaa atttgactat tcttccaaat ctggcggtgt gatatgcgag aaacactggc
    51721 caatggacga acaccgttat catgcagatc ctcgcgctgt ttatttcgtt cgaatgtttt
    51781 cggctatttc ttatgataag atcagtggaa tccacttgaa agaagaaacg aagcaggcaa
    51841 tccgtgacct cattgaccag ttgtatgatg aatatgtcgg tattcatcta aaaagcaaaa
    51901 agttcattga tcaaatgaag tcttgggcac acgtattaaa gacgccagag aaaaatatgc
    51961 ctgaaaaaga gatacctgaa aaagaagaat aaatgaaaga tacaacaaaa aaatcaaaac
    52021 tatttgacaa atacagggac ttccgtctat tattaaccgt agattaaata gatcgttcac
    52081 tgagaggatc tattatataa acaagaaaac tgcaaaatga atacgtacat tgaccaagat
    52141 cagtaaaaaa cacgtggttt agcgagttcg ggagagtgga agccggaccc aaacgatttt
    52201 tgaagaggca cttgcgagta cgataaatga agctgccgaa tctttattcg gaagtagggt
    52261 ggaaccgcga aattattcgt ccctatgtct gtaatcagac atagggactt tttgtcgttt
    52321 tctttcctgt attcttattg acagcaacgc ttaaaaattg aaaggggcaa aacagatgag
    52381 taaaaaattg accgtccaag atatgatttt aacattacaa aaattttggt catcaaacgg
    52441 ctgcatgctg atgcaagctt atgacacaga aaaaggagca ggtacgatga gcccatatac
    52501 attcttacgg gcaatcggac cggaaccatg gaatgctgct tatgtagagc catcccgccg
    52561 accagctgac gggcgttatg gagaaaaccc aaaccgtttg tatcagcatc atcaatttca
    52621 agtcgtaatg aaaccttcac ctgaaaatat ccaagagctt tatttagaaa gcttgcgtct
    52681 tttaggaatt gatccattag aacacgatat tcgttttgtt gaagacaact gggagaaccc
    52741 atcgatgggg tgtgccggtg tgggttggga agtatggctt gatgggatgg agatcacaca
    52801 attcacgtac ttccagcaag tcggaggact accttgtaaa ccagttactt ctgagatcac
    52861 ttatggacta gaacgtcttg cttcatatat tcaagaagtt gaaagtgtct atgatctgga
    52921 atgggctgat ggtgtgaaat atggcgagat cttcaaacaa ccagaatatg aacattccaa
    52981 atattctttt gaagtaagtg accaagactt gctactaagc aactttgacc gttttgaaaa
    53041 agaagctaaa cgctgtatcg atgaaaatct tgttcatcca gcgtatgatt atattttgaa
    53101 atgcagccat acattcaatt tattagatgc tcgcggtgca gtatccgtaa cagaacgagc
    53161 aggttatctt tcccgtatcc gcaacatggc tcgtgctgta gccaaaatct ttgtggcaga
    53221 acgcgaaaaa ttaggattcc ctttattgaa taaaaacaca gcaaatccag aaaacatgaa
    53281 ggaggctgaa taagatggca aaagacttat tacttgaaat cgggctggaa gaaatgcctg
    53341 ctcatgttgt cacaccaagc atgaaacaat tagaagaaaa aacagcaaaa tttttagatg
    53401 aaaaccaatt gacttatgat acgatcgaaa cgttttctac accgcgccgc ttagcaatca
    53461 aagtaacaaa cattccagaa cgtcaagcag acagcgaaga agaagtcaaa ggaccagcca
    53521 aaaaaattgc tttggacgca gatggaaact ggacgaaagc agctgaagga tttgtccgcg
    53581 gacaaggtct gacgacagat gctatcactt ttagagaatt aaaaggcgtg gaatatgtct
    53641 atgtaacgaa atacactcac ggcaaagaag caaaagaagt attgacaggt ttagcagatg
    53701 tcattaaaag cctcactttc ccagtaacga tgcactgggc agaatacgat tttgaatata
    53761 ttcgccctat tcactggatc gtggcattgt tagatgacga aataatcccg tttgagatct
    53821 tggatgtcaa aacagacaga gcttcaagag gtcatcgttt cttaggcgaa gatgtgacat
    53881 ttacgcatgc aaaagaatac gaagaaaaat tgaatgaaca atttgttatt gcttcaccgc
    53941 aaaaaagaaa agaaatgatc atcacacaag caaacgaatt agccgaaaaa aatcactgga
    54001 tcattgatct agatgaagat ttactagaag aagtcaacaa tttagtcgaa tatccaactg
    54061 tcttttctgg cgacttcgaa gaaaaatatc tatctgttcc tgaagaagta ctagtcactt
    54121 ctatgaaaga acatcaacgt tatttcgaag tacggaacga tcaaggtatg ttgcttcctc
    54181 attttatttc tgctcgtaat ggcgatcggg taaaattgga aaatgtggta cgaggcaatc
    54241 aaaaagtatt gacggctcgt ttagaagatg cggaattctt ttataatgaa gacaagaaag
    54301 cttcaatcga ccaatacgtt gaaaaattaa aaactgttac tttccatgaa aaaatcggta
    54361 gcatctatga gaaaatgcaa cgggtacaag tcatcgctcg catcataggc gaacaagtag
    54421 gactatctga ggaagaattg atggatctgc aacgcgctgc tgaaatctat aaatttgatc
    54481 tagtaaccaa catggtagga gaattccctg aactacaagg gatcatggga gaaaaatatg
    54541 ctctgctgaa aggcgagaaa ccagccgtag caacagcgat ccgtgaacat tacatgccta
    54601 tatccagtga aggagattta cctgagacta cagtaggttc tgttttagcg attgctgata
    54661 aattagatag tatcttttct ttctttgcag ttgggatgat cccaagtggc tcaaacgatc
    54721 catatgcttt gcgccgtcaa gcatatggtg tcgttcgaat catcgaatcg aaaaaatggg
    54781 cctttccttt gtctgttctg caagaaacga ttagtgaagt tatcagtaaa gatacggatc
    54841 gttttggcat tggcttgtca gcgggacaac aacaggtgat cgactttatc aaaggccgtc
    54901 tgcgccaatt attgacaacg aagaatatcc gtcatgatgt catcgaagct gttttgaatg
    54961 cagaacaaaa agatctgaca aaagtatttg cagcagcaca attgttcaag cagcatcttg
    55021 cagatgaaga cttcaaacca tcgatggaag ctttgacacg tgtcgtgaac ttagcgaaaa
    55081 aagcggagct tgaaaaacaa tcagaagtag accctgaact gttcgaaaac gaagcggaga
    55141 aagaactgca caaagcagta gaggcaatga aaacaagctt tgctgaccaa acgatcaacg
    55201 aaaattatga tcagcttgta agccttcgcc cactgatcga aaattatttt gatcagacga
    55261 tggtcatggc agaagaacca gcagtacgta agaaccgatt aacgcaatta agtcaaattg
    55321 ctgccatggc tttgtcacta gcaagtttag atcaaatcat cacaaaataa tttctaatat
    55381 gtaaataaac cagagaacag gcacaaaata ggctatttct ctggtttatt tgttataaat
    55441 ataaataact attattaatt caatgttaat ttttttgtta ttt
//
LOCUS       DAFLWC010000007        53057 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.007, whole genome shotgun sequence.
ACCESSION   DAFLWC010000007 DAFLWC010000000
VERSION     DAFLWC010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 53057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53057
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.007"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(94..1137)
                     /locus_tag="L1V17_000396"
     CDS             complement(94..1137)
                     /locus_tag="L1V17_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBN1235190.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(1514..2479)
                     /locus_tag="L1V17_000397"
     CDS             complement(1514..2479)
                     /locus_tag="L1V17_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBN1235191.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            2713..3558
                     /locus_tag="L1V17_000398"
     CDS             2713..3558
                     /locus_tag="L1V17_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1235192.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            3749..4936
                     /locus_tag="L1V17_000399"
     CDS             3749..4936
                     /locus_tag="L1V17_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBN1235193.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            4942..5298
                     /locus_tag="L1V17_000400"
     CDS             4942..5298
                     /locus_tag="L1V17_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBN1235194.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            5300..5638
                     /locus_tag="L1V17_000401"
     CDS             5300..5638
                     /locus_tag="L1V17_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HBN1235195.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     misc_binding    5714..5970
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6033..7067
                     /locus_tag="L1V17_000402"
     CDS             6033..7067
                     /locus_tag="L1V17_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1235196.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            7060..7746
                     /locus_tag="L1V17_000403"
     CDS             7060..7746
                     /locus_tag="L1V17_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1235197.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            7770..8618
                     /locus_tag="L1V17_000404"
     CDS             7770..8618
                     /locus_tag="L1V17_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBN1235198.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            8815..9588
                     /gene="sufC"
                     /locus_tag="L1V17_000405"
     CDS             8815..9588
                     /gene="sufC"
                     /locus_tag="L1V17_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HBN1235199.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            9601..10887
                     /gene="sufD"
                     /locus_tag="L1V17_000406"
     CDS             9601..10887
                     /gene="sufD"
                     /locus_tag="L1V17_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HBN1235200.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            10884..12119
                     /locus_tag="L1V17_000407"
     CDS             10884..12119
                     /locus_tag="L1V17_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBN1235201.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            12106..12576
                     /locus_tag="L1V17_000408"
     CDS             12106..12576
                     /locus_tag="L1V17_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HBN1235202.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            12581..13972
                     /gene="sufB"
                     /locus_tag="L1V17_000409"
     CDS             12581..13972
                     /gene="sufB"
                     /locus_tag="L1V17_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HBN1235203.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(14070..15212)
                     /locus_tag="L1V17_000410"
     CDS             complement(14070..15212)
                     /locus_tag="L1V17_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1235204.1"
                     /translation="MATFFSYKLQNGEKYWGFETYLGKDPKTGKDIRTKRRRFKSKAE
                     AQTALNRLLVDFKEKQEFKINVTTFQELYELWIDNYRTRVKPSSVAVAQRFCKNHILP
                     AFGELRLDKISVSYCQKQVNEWHKTLKQYGFLRKTTAQIFKFGVAMEVCKDNPMSKTL
                     LPRKIEEEQPLKFYTKDQLQLFLQNTKENNSVKLYTFFRLLAYTGMRKSEALALQWED
                     IDYFNKTITIGKTIAQDEFNQVVLQVPKTKNSSRTIQLDDFTLKQLRIWQQEQMKIMI
                     LYGYNTNSPKQFLFTTNTNKLYYPQVVNDWLDWIYKKTPMEPQITPHGFRHTHCSLLF
                     ESGASIKEVQERLGHKDIKTTMNIYAHVTPQSVKKTGDRFAKFMGE"
     gene            complement(15263..16060)
                     /locus_tag="L1V17_000411"
     CDS             complement(15263..16060)
                     /locus_tag="L1V17_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1235205.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSDTFSLDKDYELLNPIIKNIFTKYYSKDFEIYLNEILANNINPLIEEYANQRH
                     SISKELFFKRANSKLQDKIRNGDFKYGEKERMIDSLKQLLDEMDLAYKDISKYSSVED
                     FFYKITKNQFETEKFISDLSKKYNFPYEKNSIIAKFLTDNHDKFKNN"
     gene            16262..16561
                     /locus_tag="L1V17_000412"
     CDS             16262..16561
                     /locus_tag="L1V17_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1235206.1"
                     /translation="MEAIKLMISEEQEEMFLKQFYQIATKAIEKAQENAGMTREYLNQ
                     KEMAEYLNVSENFLKNAVRNEGLPVVELGARKFYSKKAVNEFMFARMKRGENIGR"
     gene            16826..17701
                     /locus_tag="L1V17_000413"
     CDS             16826..17701
                     /locus_tag="L1V17_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235207.1"
                     /translation="MNAIVILAEITYWYRPKKIFNDDGQLLGYQKKFLEDILQKSYKQ
                     LSKKTGLSERAIKDAIVYLEKKGIIKRVFRNIYYEKRAVTLSNVMYIVLNVHKLIEIT
                     FPTLDCEKKEYMPKIRQRGIEKKRYVSLKKGRGMYKFVYTYTKTTSQNISKTTLVMEE
                     EDINIKRIYSKISVLYDANNEDGRKLFQVYHYLRNANVDTEDIRKIIEYLSENTQYLI
                     AECIIKQHEACFFQRKTEEGLYDYVTYFLNGLQKRYKSQFLENVEPIDQFKKAFEIKE
                     LPEITMHNWLKGEES"
     gene            17698..17916
                     /locus_tag="L1V17_000414"
     CDS             17698..17916
                     /locus_tag="L1V17_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235208.1"
                     /translation="MIKNRLIDQMWCLDQNTDTLELIESICFNTVVLDLRAENDNCVT
                     HIIINQKMAQQLSESLRKWAEGENYESN"
     gene            17903..20530
                     /locus_tag="L1V17_000415"
     CDS             17903..20530
                     /locus_tag="L1V17_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235209.1"
                     /translation="MKAIKEKIVSRKINWLALSVLVLMISVVFTSNIVEASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSVINTIVVGLMILSLMFVGYKMITGKGTIDLRSVGMNIVMSVALI
                     LLMPTMISSGIQFAKIFYNDATTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNKLTRKNFQQTDLTQVLTDKVIDKLEKENPAADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNAGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSTGFNRAKGSGN
                     GNGSDSGEGEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERAIK
                     PFKSMRDMANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSMPTRLSDR
                     KDGAKVENADRIMSSSERMREAMKNNAESNNNPVSAIQQKVQQDIEERKNAMHGQAKS
                     AEELINQKRQEAKYTPEAMNREEMLRKRVEGRTGANTDEKEALTKERIQEAKNSNTGL
                     EKLVKENLQNSTSSQGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNGQGTKTIDV
                     RENVQNSTSSQGFKSMDVRENVQNSTSSQGFKSMDVRENVQSSTSSQGFKTVDVRENV
                     QKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKPRRRFTYEDNE
                     LFRDTLNDPNPLFDNLLKK"
     gene            20545..20763
                     /locus_tag="L1V17_000416"
     CDS             20545..20763
                     /locus_tag="L1V17_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235210.1"
                     /translation="MKLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKHEIKNNLKYCYLEKSEEIIHELNGF"
     gene            22282..22596
                     /locus_tag="L1V17_000417"
     CDS             22282..22596
                     /locus_tag="L1V17_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235211.1"
                     /translation="MADENKVVPLETLVINKEEFEQLFLDFFVQYDRIYDFSSSLDLF
                     ELEAEIIENSREENGKIIISVEKFNELFSETFEIDTDYYQPQEVFQSFRNQIIRSGKT
                     VN"
     gene            complement(22649..23422)
                     /locus_tag="L1V17_000418"
     CDS             complement(22649..23422)
                     /locus_tag="L1V17_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235212.1"
                     /translation="MKKFAIILTCALLIGTISGCTTSDTSSTSTETSTTTSEKNYPIH
                     FFPVPDGFEAYYHDKKLDVPLSETESTEKILPIEIERNQDDIKLKADLPLLNSTQIDR
                     HENIKVNIEKGALAQLYTEKVEQFFEAGANKDFSKISDYSDNFFNETQDEITNSTFMA
                     EDMYNMKLKKIKSYDYPLNLTLNKGILSFVLAGYVDYEYTADYLETPLQHDNNDINFR
                     FIYNSKSKTWLVDQLSTINTGFHELPKPDNETALVIKTF"
     gene            23527..23772
                     /locus_tag="L1V17_000419"
     CDS             23527..23772
                     /locus_tag="L1V17_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1235213.1"
                     /translation="MLFLKEEKIIDKENVIGSNIRRVRLEKGIGQTELIRDLQLRKIA
                     ITRETLVKIEGGRQHIKLDQLKAIKDILQVSYEDLLQ"
     gene            23928..24779
                     /locus_tag="L1V17_000420"
     CDS             23928..24779
                     /locus_tag="L1V17_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HBN1235214.1"
                     /translation="MYKAYELDFTNADLNAFSSSSQSYTHVVNQIDHNQKSINKRIEN
                     LFESENDLVDYYSKDSKILDADEIIKDWFPTIKADIFISHSHADEKLAIRFASWLFEN
                     FGLTAFIDSSVWGYSSDLLKKIDQKYCYKEQTKTYDYDKRNVTTSHVHMMLSTALNNM
                     IDSTECLFFLNTPNSISLSNEITNEQKFTYSPWLYSELTTASIVEKKNPRLESNPQMS
                     TEDVRSIIKHYSSQENLQIKYSLNLSELTYLRKADLKKWALDAVECTKGSNTLDILYK
                     NTIFTNL"
     gene            24812..25486
                     /locus_tag="L1V17_000421"
                     /pseudo
     CDS             24812..25486
                     /locus_tag="L1V17_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287699.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
     gene            25743..25931
                     /locus_tag="L1V17_000422"
                     /pseudo
     CDS             25743..25931
                     /locus_tag="L1V17_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604486.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            25977..26942
                     /locus_tag="L1V17_000423"
     CDS             25977..26942
                     /locus_tag="L1V17_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1235215.1"
                     /translation="MAVFRVEKNKGYTVMSNHHLRNKNLTLKAKGLLSQMLSLPEDWD
                     YTLKGLSYINRESIDAIRTAVWELEKAGYIRREQGRDAKGKMADMVYTIYEQPVLENP
                     VLENPTSDNPVLENPTSDNPASENPTQLNKEVQRTDLSKKEKIITDGQSTHSIPIPSP
                     TPAPMEGEAAATPPERKRTGKDEAVRIYREIILENIEYAYLIQDRSIDREQLDEIVDL
                     MLETVCTARKTIRVAGDDYPAELVKSKYMKLTGEHIRFVLDCLRENTTKVRNIKQYLR
                     AMLFNAPSTISNYYTALVAHDMAQPDWGKPKSGLPDYSCGEGESL"
     gene            26964..27176
                     /locus_tag="L1V17_000424"
     CDS             26964..27176
                     /locus_tag="L1V17_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBN1235216.1"
                     /translation="MKQGALIFDERTDRYDIRFDLADYYGGLHCGECFDVMIGGKWRP
                     TRIEMAENWYLVGIRADDLSGLRVRI"
     gene            27251..27727
                     /locus_tag="L1V17_000425"
     CDS             27251..27727
                     /locus_tag="L1V17_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HBN1235217.1"
                     /translation="MQEEVTQKTIALSMKTGKLTAQVLQAALKKYLQHRAKGKNTLHH
                     GQQSLKQLKKHGADLSNIEITEANIGAFKPCAKKYGVDFTLRKDKTTQPPHYVVIFKA
                     KDADNLDLAFREFTAKTLSKEQRPSIRKVLSAVKQKAAAQTKQRAKEKIKERGLEL"
     gene            27724..29532
                     /locus_tag="L1V17_000426"
     CDS             27724..29532
                     /locus_tag="L1V17_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBN1235218.1"
                     /translation="MKPDVKKLLILNLPYLIFVYLFAKCGEAYRLAAGADLSGKLLHF
                     ADGFAAAFANPLPSLHLFDLCIGIAGAVIVRLVVYCKSKNVKKYRKGMEYGSARWGTA
                     KDIAPYIDPKFENNILLTQTERLTMTGRPKDPKTARNKNVLVIGGSGSGKTRFFVKPN
                     LMQCFPTTDYPTSFVVTDPKGTLVLETGRMFQQAGYRIKILNTINFSKSMKYNPFVYI
                     HSEKDVLKLVNTLISNTKGEGEKSAEDFWVKSERLFYSALIGYIWYEAPAEEMNFSTL
                     LEMINASEAREDDPEFQSPVDLMFERLEQKDPDHFAVRQYKKFLLSAGKTRSSILISC
                     GARLAPFDIREVRELMEDDEMELDTIGDEKTVLYLIMSDTDTTFNFILAMLQSQLINL
                     LCDRADDVYGGRLPVHVRLILDEFANIGQIPNFDKLIATIRSREISASIILQSQSQLK
                     AIYKDAAEIISDNCDSVLFLSGRGKNAKEISDALGKETIDSFNTSENRGSQTSHGLNY
                     QKLGKELMSQDEIAVMDGGKCILQLRGVRPFLSEKFDITKHPRYKYLADADKKNTFDV
                     DRFLTITRRKRQQVVTQDEVFDLYEIDLSDEDAAAE"
     gene            29609..29824
                     /locus_tag="L1V17_000427"
     CDS             29609..29824
                     /locus_tag="L1V17_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016147847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HBN1235219.1"
                     /translation="MAFFNSAVTTLQTIVIGLGGALCVWGGINLLEGYGQDNPGAKSQ
                     GVKQLVAGGGVALIGVTLVPLLSGLLG"
     gene            29916..30779
                     /locus_tag="L1V17_000428"
     CDS             29916..30779
                     /locus_tag="L1V17_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235220.1"
                     /translation="MISEIIEEWIKGILMDGITGNLSGLFDTVNAKVGEIAADVGRTP
                     QAWNSGIFNMLHSLSETVIVPIAGAILALVMCYELIQMITEKNNMHDFDSSMFFRWIF
                     KSAFAILIVTNTWNIVMGVFDATQSVVNQSAGVIIGQTSIDFNTLIPDLESQLEAMSV
                     GALLGLWFQTLVVGLTMNILSICIFLVTYGRMVEIYVVTSLGPIPLATMGNAEWRGMG
                     QGYLKSLLALGFQAFLIMVVVGIYAVLIQNIGSASDISGAIWGCMGYTVLLCFCLFKT
                     GSISKAVFGAH"
     gene            30816..31352
                     /locus_tag="L1V17_000429"
     CDS             30816..31352
                     /locus_tag="L1V17_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methyltransferase"
                     /protein_id="HBN1235221.1"
                     /translation="MSTYNIIYADPPWRYDCKNVQGAAENHYSTMSIDELCALPVERL
                     ASKDCLLFLWATFPMLPEALRLIKAWGFSFKTVAFVWLKQNRKSLTWFYGLGRWTRGN
                     AEICLLATHGKPKRRSASVHQFIISPIEQHSKKPDVTREKIVELAGDLPRVELFARQK
                     TPGWDVWGNEVECDLILT"
     gene            31366..31788
                     /locus_tag="L1V17_000430"
     CDS             31366..31788
                     /locus_tag="L1V17_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBN1235222.1"
                     /translation="MAYVTVPKDLTHVKSKVVFGLTKRQLICFSGALVIGVPLYFLTR
                     DYLTNSAAALLMVFAMLPGFLLAMYERHGQPLEVVIMQIIQCCFIQPKERPYQTDNTY
                     TALVRQYQMEQEVKAIVQKGNPKRNRKNKADPRPAKRN"
     gene            31718..34117
                     /locus_tag="L1V17_000431"
     CDS             31718..34117
                     /locus_tag="L1V17_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBN1235223.1"
                     /translation="MSKKEIPRETEKTKLTRAQRKEIDAVIRKYKGDGRPHTAQQSIP
                     YEVMYPDGVCRVSPGVFSKCIEFADISYQLAQPDTQTAIFEKLCDLYNYVDASIHIQF
                     SFLNRKVDPVQYAKSFEIAPQGDDFDDIRAEYTGILQKQLANGNNGMVKTKYLTFTIE
                     AESVKAARARLKRIGFDLLGYFKSMGAVAHVMDGWERLNLLHGVYHPDGEIFNFDWKW
                     LAPSGLSTKDFIAPSSLCFGNAKTFGMGGKYGAVSFLQILSPELSDDMLADFLNTESG
                     VLVNLHVQAIEQTKAIKTIKRKITDLDAMKIAEQKKAVRSGYDMDILPSDLATYGEDA
                     KKLLTKLQTRNERLFQLTFLVLNVADTKQKLNNDVFQAAGVAQKHNCPLVRLDYQQEQ
                     GLASSLPLGVNQIKIQRSLTTSSVAVFVPFVTQELFQGGAAMYYGINAKSRNMIMLDR
                     KQARCPNALKLGTPGSGKSMSCKSEIVSVFLTTPDDIFISDPEAEYYPLVKRLHGQVI
                     RLSPTSKDFVNPLDINLNYSEDDNPLALKSDFVLSFCELVMGGKNGLEAIEKTVIDRA
                     VRVIYRPYLADPRPENMPILSDLHKALLDQHVPEADRVAQALDLYVSGSLNVFNHRTN
                     VDIGNRLVSFDIKELGKQLKKLGMLIVQDQIWGRVTANRSQGKATWYFADEFHLLLKE
                     EQTAAYSAEIWKRFRKWGGIPTGATQNVKDLLSSPEIENILENSDFITLLNQASGDRK
                     ILAERLNLSTEQQKYIDNSEPGEGLLIFENVVLPFTNPIPHNTQLYKIMTTRLNEVAG
                     V"
     gene            34149..36140
                     /locus_tag="L1V17_000432"
     CDS             34149..36140
                     /locus_tag="L1V17_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBN1235224.1"
                     /translation="MKELKAKAKVTQAMTRDGLTLENQATGEVENISSREAEQDLSAP
                     GPGGTADKLLERADAIHDGHKAKKAAKQAGAVAAEGDAALHRPSARLQLSEEERADPD
                     LQPYIRKSDKRADKLDKARAAIPKKRVPVKETVFDEASGKAKTVLHFDKQDKGPPSLK
                     PNPAGRPVSEVFLFGHGKIHEVEHENVGVEGGHKGEELAERQAGKAIRSTIRHHRLKP
                     YWDAEKAERRLLSANAEYFYQKSLRDNPEIAQAASNPISRFWQKQQIKRQYAKAARTA
                     GQTAGAAAQGAAKTAGASTKAAKAAAKESERAASFVARHWKGALAVLVLGLLMLLIIG
                     GLQSCTAMFGSAGSGITASSYFSEDSDMLAAEDAYAELEAELQDYLDNYEATHDYDEY
                     HFDLDEISHDPYVLISILSALHDGIFTIGEVQGDLSMLFDKQYILTENVVVETRYRTE
                     TDTWTDAEGNTHTDTYQVPYDYYICYVTLENFDLSHVPVYIMDEETLSFYSLYMSTLG
                     NRPDLFSGSQYPNASTLTPPTYYDVPPEALEDATFAAMLKEAEKYIGYPYVWGGSSPS
                     TSFDCSGFISWVINHSGWNVGRLGAQGLYNICTPVSSSQAKPGDLVFFKGTYDTPGVS
                     HVGLYVGNNVMLHCGNPISYTNLTSNYWQSHFYSYGRLP"
     gene            36163..36414
                     /locus_tag="L1V17_000433"
     CDS             36163..36414
                     /locus_tag="L1V17_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HBN1235225.1"
                     /translation="MATKLDRIEKDIQKTKSKIAEFQKQLRELETQKTEQENLQIIQL
                     VRGMNMKPEEFAAFLRSGAMQAAPAATPYHEQEDNAHEE"
     gene            36404..37633
                     /locus_tag="L1V17_000434"
     CDS             36404..37633
                     /locus_tag="L1V17_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HBN1235226.1"
                     /translation="MKNKTRRISRILPALLAVMLCVTAFPVTALAGGNDPAPAPLPEA
                     TTEPATGGLEPETDETGTATDGTETEAEKDTGPLTGKDITDLFSALFGSKVSIAATDD
                     GIQITTGTDKKEPEQTGTVTTNGGRLNVRTGAGLDKTAFTQLPNGTTVEVVGTDGDWI
                     KILLPERIGYVHSDYMTVSEKEVAATGEGGFSLSIDPEEIASLLELFNGGGASAALSP
                     DGNLSLIDDIGSAAKNGKQFITVETKNGNVFYLIIDRDDEGKETVHFLNQVDEADLLT
                     LMEDGETVTPAAVCSCTTKCKAGAVNTNCPVCKTNLTECSGPEPQEPQPEEPEAPEEE
                     PKGGAGGLIVFLLVALAGGGAALYYFKFKKPKAETTGSDDLGEYDFGEDEDLEDEEPE
                     TEFDPEADFVSEQEDEE"
     gene            37630..39711
                     /locus_tag="L1V17_000435"
     CDS             37630..39711
                     /locus_tag="L1V17_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HBN1235227.1"
                     /translation="MTYKLVIAEKPSVARSIAGVIGATEKHDGYLEGNGYLVSWCIGH
                     LVSFADAGRYDERFKKWRYEDLPILPETWQYIVPDDKKQQFDVLCSLMQRPDVTGLVC
                     ATDAGREGELIFRFVYQMAGCQKPFERLWISSMEDSAIKDGFAHLKPGGDYDPLYQSA
                     LCRAKADWLIGINATRLFSVLYHKNLTVGRVQTPTLKMLVDRDAKITDFKKEKYHIVH
                     ITAGGADAVSSRFSDAAEANTVKAACAKAQAVCVSVTREKKTEQPPKLYDLTTLQREA
                     NRLFGYTAKQTLDYAQALYLKKLLTYPRTDSQYLTDDMLPAVESLVSGLWELVPFAKG
                     LNLSPQFDRILNSKKVSDHHAIIPTAEFVKQGFGTLAESEKKLLSLICCKLLCAVAGP
                     HIYEAVTATFTCAGQEFTAKGKTVLSPGWKEIERRFRSSLKTDADEDAEAVRELPELC
                     EGQTFADVAASVTEHFTTPPKPYTEDTLLSAMERAGAEDMPEDAERKGLGTPATRAAI
                     LEKLVQMGFVQRKGKQLIPTKDGINLAVVLPEALTSPQLTAEWENRLTEIAKGQADPD
                     EFMDGIETQARELVQTYSCISEEKQKLFQAERVPIGTCPRCGEAVYEGKKNYYCGNRA
                     CQFVMWKNDRFFEERKKAFTPKIAAALLKTGKVKVKGLYSVKTGKTYDGTVLLADTGG
                     KYVNYRIEHRS"
     gene            39860..43780
                     /locus_tag="L1V17_000436"
     CDS             39860..43780
                     /locus_tag="L1V17_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
                     /protein_id="HBN1235228.1"
                     /translation="MNEVFSIQVHNRQFLEQGKQGVWLDLPTTTETLQAALRDVGITA
                     DNPQDFFINGYSCPEDRHLAIPYDMVLAADVDELNFLAARLGQLDAAEIAELNAALQN
                     PRGGFENIGQIIDYTENVDYYVHLPDVRGDGQLGDYYLNRSGMVDMPEEWKAGIDTAQ
                     FGRHIAQQEQGVFTQYGYLVRSGDEWQRVHEGQPVPEEYRVMHYPQPEADREEPQAQQ
                     PEASESPDKAPPPVIPIMLDGMNSKERMKVITDRLETGVQELFESSRYMAYLSAMSKM
                     HDYSLNNTLLIAMQGGSIVAGYNRWQDEFDRHVKRGEKGIKILAPAPFKVKQQMEKTD
                     PATQQPVIGADGKPVTEEQEVTVPAFKVVTVFDISQTEGKDFPMPYISELTGDVQQYQ
                     DFFAALERTSPYPISIEPISDGAKGRCFYAKQRIAINEGMSELQTLKTAIHEIAHAKL
                     HAIDREAPAEEQAARPDRSTREVQAESVAYTVCQYYGLDTSDYSFGYVADWSSGRELS
                     ELKASLETIRATASELITEIDGHFAQLQQEREARQEQEAVTVDVTPEAAAPAQAEEEQ
                     APALDPAAEPLVTVLWSESPQLKDGQQMPLHEADALFARLDAAYPAEAGYDKTAFRID
                     CIFQGEPDSYEGRQDFGDRDGSLIEHIQSYHQFYAQDENWKKHVIATTGIEGWEQDKA
                     HRDMLLGEFVPYMKLHCSLAQMEQTAQGRLQSGETLTPEETAYLGALLSYVQECRPML
                     NQGQYQLPEPPKLADFDQSLQDYKAQVQAEIAQEAAAAGMTVEEYAAAGYEAPQQDTF
                     SIYQLRGGEETRDYRFEPYERLQAAGLAVDSANYDLVYTAPLDKSTSLEDIYRTFNID
                     HPADFRGHSLSVSDVVVLHQNGQDTAHYVDSFGYMEVPEFLRENPLRTAELSTEQNEN
                     MIDGIINNTPPEPQPEEPEQLSFEDVAVASGQTQEEPPEAAPPQTAVRYYPINEGAAR
                     RAKEAMSFSDYRPGSATAEYRHYVDQAVEIAERQKKRVEPEYHEKIDSLLDTYARKLA
                     ENMNKGYEITARVPSVLIAGPSNFPVRAKEKQNAASDRNMEEFQYIQGLLDKIRSTGM
                     GGISADDPQAVSKLEKKLEKLEASQELMKAVNAYYRKHGTLDGCPHLIERGIENLKAD
                     MASGWHYEKKPFQSWQLSNNNAEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRVA
                     NRLQIFFEGKPDAAVRDELKSNGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGEK
                     PSALQLAARREKEKPSIRAQLNAAKTEQAKQPPAREKSKGLEVE"
     gene            43781..44725
                     /locus_tag="L1V17_000437"
     CDS             43781..44725
                     /locus_tag="L1V17_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235229.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            44729..44932
                     /locus_tag="L1V17_000438"
     CDS             44729..44932
                     /locus_tag="L1V17_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HBN1235230.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMPVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(45232..45468)
                     /locus_tag="L1V17_000439"
     CDS             complement(45232..45468)
                     /locus_tag="L1V17_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1235231.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(45651..46037)
                     /locus_tag="L1V17_000440"
     CDS             complement(45651..46037)
                     /locus_tag="L1V17_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HBN1235232.1"
                     /translation="MDARAMSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECI
                     CVQSISYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAA
                     CSKRMRRRKEAERQRKRYWKPTHLEL"
     gene            complement(46019..47347)
                     /locus_tag="L1V17_000441"
     CDS             complement(46019..47347)
                     /locus_tag="L1V17_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBN1235233.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            complement(47308..47637)
                     /gene="mobC"
                     /locus_tag="L1V17_000442"
     CDS             complement(47308..47637)
                     /gene="mobC"
                     /locus_tag="L1V17_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBN1235234.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            complement(47895..48265)
                     /locus_tag="L1V17_000443"
                     /pseudo
     CDS             complement(47895..48265)
                     /locus_tag="L1V17_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            48410..48595
                     /locus_tag="L1V17_000444"
     CDS             48410..48595
                     /locus_tag="L1V17_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBN1235235.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            48753..48920
                     /locus_tag="L1V17_000445"
     CDS             48753..48920
                     /locus_tag="L1V17_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235236.1"
                     /translation="MKKRNFIMTEMENARNKDEEAAAVSAVYGRIEKAGIWILYGEVS
                     RHWITAGLMRL"
     gene            49538..50197
                     /gene="vanR"
                     /locus_tag="L1V17_000446"
     CDS             49538..50197
                     /gene="vanR"
                     /locus_tag="L1V17_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance response
                     regulator transcription factor VanR"
                     /protein_id="HBN1235237.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            50200..51561
                     /gene="vanS"
                     /locus_tag="L1V17_000447"
     CDS             50200..51561
                     /gene="vanS"
                     /locus_tag="L1V17_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBN1235238.1"
                     /translation="MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPNFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQARSRKSGRSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLT
                     STL"
     gene            complement(51652..52953)
                     /locus_tag="L1V17_000448"
     CDS             complement(51652..52953)
                     /locus_tag="L1V17_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBN1235239.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT        15717 a        11382 c        12566 g        13392 t
ORIGIN      
        1 tgttgttgtt agaaggatat ctgcaaaatt aaaaacagtt gtgattcgga cattgttcca
       61 tgcgagaatc acaactgttt tttcatgttc attctaaact ttgatcagcc aaataaatag
      121 taaagccatc actgtttgga gaagcccgac agctaatcca taagataaga agcgtgtacc
      181 ttctttcatg aattttgcaa agtctaaacg cagaccaatt gccgctaaag cagtgatctc
      241 aaaccagctg ctgataaaat gtgccgattg gtcaataact acaggtaaag aaaacaagct
      301 gttgaccaaa caaaagatca caaaccctaa tacataccaa ggaagcggta attttcgttt
      361 tttctgcgta tcagttggcg tttcaaacag agctggttgt ttcttgtgca tgaatttttc
      421 aaacagatag acaacaacaa cgagcatcat aatacgtaga atcttaaata gcatggcgaa
      481 ttcgacaaca gaattgtcaa gtaagcttgc cccagcgact acttgaccaa cagattggag
      541 tgtaccaccc aaaagtgcac ttttttcaat gagatttcca ccaaacaact gtaatccaag
      601 aaaagggaga gtcaacatca tcacagtacc cagtagattg actagtgtga tgatctgtcc
      661 tttttcttcc tctttcgcat ggatggaagg ggcgattgaa gcaatagcag aagaaccaca
      721 aacagcgttt cctccagcca tcatcaaaga agaagtatcg ctgaattgca gttttttacc
      781 aatcaagtaa gcaccgatga tagtgactga catttgcagt aacacaaaaa caattccttt
      841 tacaccaatt tgagcaatcg tttgagctgt gacagttgca cctagtaaaa aaacagagaa
      901 ttctaatagt ttgctttcag caaattttgt gccgattgct agaacaggct gtttaaaaaa
      961 agtatttcct aataaaatac ccaataaaat agcaatagtc gctccaccta actgtggcag
     1021 ataaatagca agaagcctgc tgaaggcagc gatggcaaaa gaaagcagta aaccgggtaa
     1081 gatttcgcgg accgctgaat cctttacaga ttttattgga tgtgacaatg atttcatttg
     1141 atcggttcct ttcgtcaata aatactaaaa gcatactcga acatagtagc actaaaccag
     1201 tattttgaca aaagaacaag aggtcgtgac aaaagtcttg tacgacctct tgtttcgaat
     1261 aaacggtgtt ccagaagtag cttctacgga aataagccga aatttcacaa aaatttgaga
     1321 agcaattttc gtaaattcct tcttatttct tgaagctgac cacttctttt acgacctctt
     1381 ggtaaacggt gttcaaaagc ttgcatctgc ggtaataagc ccaaccagta caaaaacatg
     1441 aacagctgtt tttgtttggc cgttcttatt acttgatgca gaacagcttt ttcacaacct
     1501 attgaatcga ttattaagcg atttttttag aaacaaattt tccatgtttg ctatgttctt
     1561 taattaagaa acgtacgtaa tgagcaagaa cgtagaagac aactacactt gcaaacagac
     1621 attccgcaac ttttaagaaa tccaatacgc tactatagat acctaaactg ttgaagtaat
     1681 gaacagtagt aaatatagct gttgcagaga taacaagcgg gaatgtaaag gctgcatagc
     1741 ttggataaaa acgaagcttg aacaaacgtg gaagcataga cagcacaacg aaatacaata
     1801 cttgagataa agcgaacaat gctacgacaa gataaaaatt aggttcagca aagtttttaa
     1861 gataacctgt taggcaaaga gaaccaggtg ctgcaacgat cgtaatcagc ggacgtgtcg
     1921 gatgagccat atttcttacg aaaaagacac gtttgatgat gatcggcaat aagaacgcat
     1981 agcagatcaa tgaaatccaa aagaaaattt ttccaataag tgggaagaag ttcccggcag
     2041 ttacagtgat gaccccaaat ccaacgtaaa tgataaacca gcttggataa attgcttcaa
     2101 ttgaaagatc agctttgata acatggtgat aattgaaata aaagacaagg atcacttgga
     2161 agataacagc gcacagccaa atgaatttga caattggtgc aatactttca tatgaaacaa
     2221 aataagtaca aataaccatg agtgacatcg taaaagttgg tgaaacggag gcgatgattg
     2281 gatcatgcaa cgtttgtttc gtgtgttcga ataagataaa caatttaaca aaaatgaata
     2341 tcataagaat catagagata ccgccagtta gattgcctaa agcaacatgg tgatagtctt
     2401 taaacagatt tccaagggaa gctaacccaa ggatcaaccc gcagatcggg atcggaataa
     2461 ttttcaaaaa gttcttcata tataatattc tcctttttat ttaatagatt ttagtaccaa
     2521 gatgaacgaa tacattgtaa aatgaatagg aatgtatgat tacgagcaag cagacagctg
     2581 attgtcttca tctaagttac tagttggatc agcaactgtt ttgttgtaca tttctattat
     2641 agatggtttt ttgtatattt aaatcaaata gtttttatag taattatcat aaaaagttat
     2701 ggaagtggtg ccatgtttaa gttattaacg acttttcgag cagtatatga aacaagaaat
     2761 ttttccagag cagcagaagt actgttttta tctcaaccag cagtctcgaa tcaaatcaaa
     2821 cagttggagc gggaattgaa tatcgatctt tttcaacgta acggaagaaa agagatgctt
     2881 ccaactaagc aagccgactt attatatgaa cggacactgg ttttgttaga agaatgggaa
     2941 gaaactcagc aaaaattgct caatgaacaa aatgaagaag aagtatgtcg gatcgttgct
     3001 tcccacacct ttgctgtcta tcttttgcct cagttgatga aacatctgat caaaaggttt
     3061 cctaaagtgc attttgagat cgaaatcacg aattctcatg aatcattaga acaagtagcg
     3121 aaacatgaat ccgattttgg ttttatcgaa aagccattag agacttccgg cgtacaaaga
     3181 tactctttga tggaagacca gctagtcatc gctggggacc caaaaagcaa attgtggctt
     3241 gtaagagaag caaactctgg tgtttttcat tacacgcagc gttattttga agagatgaat
     3301 atccaagata agaagatgat cgtgaaaagt aacgatgtaa ttgttgcgtt gctgaaggaa
     3361 ggaatcggtc gctcgatttt gtctaagcgc tctgttccag aaaatgtgcc aatgactccg
     3421 ttgaatttcc atcgatattt ttatttcatc caacgaacca atctggtttc tgatcagctg
     3481 ctagagattg ccgaagagat ccttcgatac aatgaaagca cagaaacttc tcacagcgag
     3541 gagaatctca gctggtagat aattgcatgt atcaaaaaaa gttctatgat acactaaaga
     3601 taagcagtag gcttttgtac tgcatttgct caagcaactg cacaaacgga aagttaattt
     3661 ttcccaaatg tctatggaaa gactttccat tatctaactg gaccgctata ataatcagca
     3721 gtatggtttt taagaaaagg gatgaaacat ggaaaaaaaa ttaaaagctt cgaacgataa
     3781 tcgtattgat tatggcgtga ttttaccagt ctttctgtta tgtttgattg gtctgctctc
     3841 attatatgta gcacttagcc atgatccgaa caatccagca gtcttgaaag gcgtagggat
     3901 gcaagttgtc tggtatttag ttggagcggc agcaatcgtt gtcatcatgc atttgaattc
     3961 caaatggatc tggaaactga ctccttacct ttatggtttg gggttagtgg taatgggact
     4021 cttgctcaaa ttctatgatc agaatttagc tgcttcaaca gggtctaaaa actggtttcg
     4081 attcggtgcg tttactttcc agccagcaga gttgatgaag attgcgtaca tcttgatgat
     4141 ggcactgatc gtaactaaac ataatacgca agtaaaagaa cggacgatga aatcggactt
     4201 ttggctgatt gggaagctct tgatcgtgac aataccggtt ttagcattga tcatggccca
     4261 agatgacttt ggaacgatgc ttgtctttct tgcgatcttt ggcgggattt tcctgatgtc
     4321 tggaatctct tggcgcatca tcgcacctgt agtaatcttg gcagtagtcg ttggagcagg
     4381 aacgatcttc ttggttacga ctgaaggcgg aagagacttg ctttataaag ttggattcaa
     4441 atcttatcag tttgcacgta ttgattcatg gctggaccct ttccatgata cgtcaggaat
     4501 gagttatcag ccggcccaag gacttttggc aattggtacc ggtggcttgt ttggtaaagg
     4561 attcaacgta agcaatatct atgtgcctgt tcgtgagtcc gatatgattt ttaccgttat
     4621 cggtgaaaac ttcggcttta tcggtggtgc attcgtcatt ttcttgtatt ttattttaat
     4681 ctatcgtatg attcgggtgt gtttcgatac gaataatgaa ttttacgcct atatcgcaag
     4741 cggtttgatc atgatgctgc tgttccatgt ctttgagaat attggagcaa atatcggatt
     4801 acttccttta acagggatcc cattgccttt cattagtcag ggaggatcct cgattttagg
     4861 gaacatgatc ggtatcgggt tgatattatc gatgagatac caaaatgaag cacctgcaag
     4921 atcttcaagg aggtaagaaa attgtacacc ttttactggt acccgaaatg ttcaacatgc
     4981 aaaaaagcca aagcgtggtt agaccagcat ggcgttagtt atcaaaccgt tgatatgatc
     5041 aaagaagtac cgaaggcctc aacgattgag acttggctag aaacgagtca agtaccaatc
     5101 cgtcgcctgt tcaacacaag cgggatgaaa tatcgggaac ttggactgaa agatcaagta
     5161 ggcgagttta cggcttcaaa agcgagccaa gtcttatcga cagatggtat gctgatcaag
     5221 cgaccactga tcttacgaga ggaccagctt gttgcaattg gattcaatga aaaaatttat
     5281 gaaggagaac tgatataaaa tggcaggcaa gcatttgaag aaaaaggaca acctttggat
     5341 cttatttaat ggaaaagaat actgtgttgg tttgacaaat gaagcgcaag aagaacttgg
     5401 agacatcacg tttgccaatc tgccaaaagc aggacaatcg ctaaaaaaag atgaacctct
     5461 gatcgaagtt gaagcggaaa aagcggtcaa tgaatttgcc agcccgctaa cgggtacagt
     5521 ttcttctgtt aatgataaaa tcggtgaaga tatcaatatc ttgaatgatt cagatgaaat
     5581 gaatgcgtgg atcttaagtt tcaaagatgt tgatccaaaa gaatttgacg aattataaaa
     5641 tcagaaaatc acttgaaaaa agttgacact gattcttcca gttgctataa tcataagcaa
     5701 tcctatatga aacgagaaag ctttgaaaag aagagtacat gtcacggacg tttgaagaga
     5761 gccctgtttg ctgaaaatgg gtaacgaaaa tgagatggaa gatggtctta gagcagagta
     5821 agcgagcgta agcaaactta ctacgggagt gcccgttaca gcgcgacagt atacggaaag
     5881 aagctaagtc caagtactgg aagaggctgt tattgcgaag taacggtaaa tcaaggtggt
     5941 aacacggaag ttcaagcttt cgtccttttg cttaaggcaa gagggcgaag gcttttttgt
     6001 ttgaaaaatt ataagagaaa gatgtgaatg gcatgtcatt aatccaacta acgaatgtca
     6061 aaaagacatt caatgggaaa aacggaaaca tccaagccgt caatgacgtt tcactaaacg
     6121 ttgaaaaagg ggatatttat ggaatcgtcg gctattctgg cgcaggaaaa agtacattag
     6181 tccgtctcct gaatggactt gagcttccca cgagcggcga agtgatcgta aacgatcaag
     6241 atattacaaa attaaaaaac aaagaattac gtacattccg aaagaaaatc ggtatgatct
     6301 tccagcattt caacctgtta tggtcaagaa ctgtacttga aaatatccag ctgccgctgg
     6361 aattagctgg cgtaccaaag agcaaacgta aagaacgggc agaagaactg ttgcgtttag
     6421 tcgggttaga aggacgcgga caagcatatc cttcacaact ttccggcgga cagaaacaac
     6481 gcgtcggtat cgcacgagca ttggcaaatg atcctgagat cctgctttgt gatgaggcta
     6541 ctagcgcatt ggacccgcaa acaacagaag aagtattaga cttattgtta gcgatcaata
     6601 agaaattgaa tttgaccatc gtcttgatca cacatgaaat gaatgtgatc cgcaaaatct
     6661 gcaacaaagt cgctgtgatg gagttgggga aagtcgtaga agaaggagac gtattgactg
     6721 tcttcagaca accgaaaaaa gaagtaacca aacgctttgt acaacaagac atcgaaccag
     6781 aagctgattc gacagaacta ttagctgaac tcatcaaaga aaatccaagc ggccgtttgg
     6841 caactttgac ctttagcgaa agaaatgcca acgagccagt catttcccaa gcgattcgac
     6901 gctataacat cgatgtcaac gttgtgtatg gaaagatcaa acaagtgaaa gaaggttcct
     6961 ttggttcatt gactgtcttg atgactggtg aaaccaaaga attagatcaa gcagaagtgt
     7021 tcatcaaaga acaaggagta ggaattgagg tgatccatcg tggataaaag cttttcagaa
     7081 acatatctag attttaaaca aatcaacccg gaaacgatga atcaggctat ccttgataca
     7141 ctatatatga cattaatctc aatggtctta gtgacgatca tcggattagt tttgggattg
     7201 atcctttact ctattggacg caaaaacaaa ccgtatgctc gaatcattta tggaatcgta
     7261 tcgatcatca gtaatatttt ccggtcaacg ccatttatga tcctgatggt tttgatcatt
     7321 ccatttacta aagcaatcgt aggcactatg ctaggtgcgc aagcagccat tccagctctt
     7381 gttttatccg cagcaccatt ttatgcccgt ctagtagaga ttgcttttcg tgaagtcagc
     7441 cctggtgtac tggaagcagc agatgcaatg ggagcaagtt actgggaaat catctggaag
     7501 gtcttgatac ctgaaagtat tcccgcattg atttctggat taacagttac aacgatctcg
     7561 atgatcggat ttactgcgat ggccggcgcg atcggcgcag gtggacttgg aggtcttgct
     7621 tggcaggaag gctaccagcg tggtaatcta acagtgacat tcgttgcgac tttaattatt
     7681 ttactaatcg tatttatcgt tcaaggaatc ggtgatttct taactaagaa aacagacaaa
     7741 agataatagg atataggggg atgtaggata tgaaaaagaa aatttttgga tttgcagcag
     7801 cgcttttgct gactgtagga ttagcagcat gcggtaacaa cagcgacagc aaagattcag
     7861 caaataaagc agacgacacg acattgaaag tcggcgcttc accgacaccg cacgcagaga
     7921 ttttggaaca tgtgaaacca ttattgaaag atgaaggaat cgatcttgaa atcgtcaaat
     7981 tcgatgacta tgtattaccg aaccaatctt tggaagaagg cgacattgat gccaattact
     8041 tccagcatat tccttatttg aacaaagaaa tcaaagaaaa aggatatgac tttgtcaatg
     8101 ccggtgctgt ccacatcgaa ccaatgggct tgtactctaa aaaagtcaaa gatgtttccg
     8161 aattaaaaga tggtgcaaca atcattactt caaattctga atcagactgg ggacgcatca
     8221 tcacaattct acaagatgct ggcttagtca aagtcaaaga tggagtagat ctggaaacag
     8281 caacattcga tgatattgaa gaaaacccta agaacttgaa gttcaaccat acgatcgacc
     8341 catcactttt agcttctacg taccaaaatg atgaaggtga cctagttgca atcaacgcaa
     8401 acttcgctta cggcgcaggg ttgaatccat tagaagatgc cgtattgctt gaaaaggaca
     8461 actctcctta cgtgaatatt attgcgactc gtaaaggtga tgaagacagt gacaaaatca
     8521 aaaaactgat tgaagtgctt caccgcaaag aagtccaaga atggatcaca gacaaatggg
     8581 gcggctctgt taaaccagta aaggctgatg caaaataagg tatggaacaa aaaagatgag
     8641 aaataagtct gtaatggctt atttctcatc ttttttatac ctattctaat ttagaaatca
     8701 aaattgttta ataataaata aaagatattt gattttagta aggaaggtca ttgcgcttca
     8761 ttctcaatta gtctaaaatg agtgagaacg aaagagaatt tgggggtata atgcatgtct
     8821 gtcttagaaa taaaaaatct acatgtgtcg atcgaggaaa aagaaatcct taaaggcgta
     8881 aacctaacaa tgaaaaccgg agaaatccat gccatcatgg gacctaacgg cacaggaaaa
     8941 tctaccttat ctgccgctat catgggcaat ccaaactatg aagtaacaga aggcgaaatt
     9001 ttgtttgacg ggaaaaatgt tttagacttg gaagtagatg aacgtgcgcg acttggctta
     9061 tttttagcta tgcaatatcc aagtgagata ccaggtatca cgaatgcgga attcatgcgt
     9121 gcagcgatca atgcgaaacg tgatgaaaac gacaaaattt ctgttatggc atttttgaaa
     9181 aagttagatg aaaaaatggc tttactaaat atgccagaag aaatggctga acgttatctg
     9241 aacgaaggtt tttctggcgg agaaaagaaa cggaatgaga tcctgcaatt gttgatgtta
     9301 gaacctacat ttgcaatttt agacgaaatc gattcaggtc tggatatcga tgctttgaaa
     9361 gtcgttgcta aaggagtaaa tgaaatgcgc ggagacaatt tcggtgcatt gatcatcacc
     9421 cactatcaac gattattgaa ctatatcaca cctgatgtcg ttcacatcat gatggaaggc
     9481 cgagtagtca tgacagggaa tgctgaccta gctaaacgtc tggaagcaga aggctacgct
     9541 ggtatcagta aagaattagg aatcgactat aaagaagaag aagcgtaagg gggagcaaga
     9601 atgaaagaaa aaaactggct cgattatctt gacgcggtaa atgatttttc tttaagtaaa
     9661 ggcgaacctg attggatgag aaccttccgt caagacgcac tagcgaaagc agatgaactg
     9721 ccattgccgc atatcgatcg ggtgaaattc catcgctggt cgttatttga tgtgaaagaa
     9781 acacaaacca tcagtgaaac aggcacgatt ccggcatttg atgcaatgaa agacaatcct
     9841 gtgcttgtcc aacaaggttc atggacgatt tttgaacaac tgcctgtgga attagcagaa
     9901 aaaggagtca tttttaccga cttgttcact gcaatgatcg aatatccaga actagtccaa
     9961 gaatattata tgaaaaaagc agtaaacatg aacgaagacc aattgactgc actccatgta
    10021 gcttttatga acagcggtat tttcctgtat gtgcctaaaa atgtcgtgat cgatgaacca
    10081 ctcgagtcct tattcattca agatggcgca tccgatgagc acttcttcaa gcatgtgttg
    10141 atcgtggcag atgaacatag tgaattttct tatctggaac gtttccagac aaccaaagaa
    10201 caagtagcaa aatcatcagg taatatcatc gtggaagtca tcgctaaagc tggttcaaaa
    10261 atcaaatatt cagccgtaga tcaattagga gaaaatatta cttcttatat gaatcgccgt
    10321 gggcacattt tacgagatgc ttctgtcgac tgggcaattg gtgtcatgaa tgacggtcat
    10381 gtgatcgctg actttgactc agatttagca ggagaaggtg cacacgcaga agtcaaaatc
    10441 gtggcaatca gctcgggcag acaaatccaa ggaatcgata cacgagtaac caataaagcc
    10501 cctcatacga tcgggcatat tttgcaacac ggagtgatcc gagaaaaagg aacattgacc
    10561 tttaatggta tcggccacat cttgaaaggg gcaaaaggtg cagatgccca acaagaaagt
    10621 cgtgtcttga tgctttctga taaagcacgt ggtgatgcga atcctattct tttgatcgat
    10681 gaaaacgaag taactgctgg acatgctgcc agtgtaggac gagttgatcc agaagaaatg
    10741 tactatctga tgagtagagg attgcataaa gaagaagcag agcgcttagt gattcgagga
    10801 ttcctcggtt ctgtcttaac agcaatccct gtagaacaag ttcggaaaga attagtcgaa
    10861 gtaatcgaag ggaagttgaa tggatgatcg atgctaaaaa gctacgcaat gattttccta
    10921 tcttatttca agacgtcaat gatgaacctt tagtttatct ggataatgca gcgacgaccc
    10981 aaaagccaaa acaagtactc caggcattag cgtactatta cgaacacgat aacgccaatg
    11041 ttcatcgcgg tgtccatacg ttagcagaac gcgcgaccca tgattatgaa caagcaagag
    11101 aaaaagtacg ggcgttcatc catgcaaaag aaacagcaga agtgctgttt actcgtggta
    11161 cgacgacaag cttgaattgg gtagccagaa ccttcggcga ccgctatatc aaagcaggag
    11221 acgagatagt gctctcttac atggaacatc attctaatgt tatcccgtgg cagcagttgg
    11281 caaaacgaac aggtgctgtc ttgaaatata tcgaactaac agaagaaggc ttcctggata
    11341 tggaggatgc agcgaaaaag attacggaca aaaccaaaat cgtctccatt gctcatgtat
    11401 ccaatgtctt aggtgtcttc aatcctgttc aagaattagc tgaacttgtc catgaaaacg
    11461 gcggggtcat cgtagtagat ggtgctcaat ctgccccgca catggccatt gatgtccaag
    11521 cactagactg tgatttcttt gctttcagcg gacacaaaat gtgcggacca acaggtattg
    11581 gtgttttata tggtaaacga aaatggttag aagaaatgga acctgttgaa tttggtggcg
    11641 aaatgatcga ttttgtcgaa ttatacgaca gtacatggaa agaactacct tggaaattcg
    11701 aagcagggac accaaatatc gccggcgcta tcgcattagg ccatgcaatc gattatttgc
    11761 aaaaactcgg tatggacaat atccatcgat atgaagaaga actagccgct tatgtgttgc
    11821 caaaattaca agcaattgat ggattgactg tttatggtcc acaagacccg aattttcgga
    11881 caggagtcgt tgcattcaat ttggatgggt tacatcccca tgatgtcgcg acagctttag
    11941 acatggaagg ggtagccgtc agagcaggtc atcattgtgc gcaaccgcta ttgaagtacc
    12001 ttgaagtatc agcgactgct cgcgcgagct tttatttcta caacacaacg caagacgccg
    12061 accgtttagt tgaagcaatc atggcaacaa aggagttttt ccaacatggg actatctaaa
    12121 ttagacaatt tataccgtca agtgatcttg gatcattctt cccatccgca tcatcgtgga
    12181 agcttgactg actcgacaag caagatcgaa ttgaacaacc ccacatgtgg agatgtgatc
    12241 gaattgcaag tcgatgtaaa agacggaatc atcaaaaata tcgcctttga cggcagtggc
    12301 tgctccatca gtacggcaag tgcctcgatg atgacagacg ccgtcatcgg aaaatcaata
    12361 gaagaagcag aacatttaac tgtagacttt ctacagcttg tccaaggaaa agaagtcaaa
    12421 gatcccgacc aattaggcga tgctgctatg cttggtggtg tagctaaatt tcccgctcgg
    12481 atcaaatgtg cgacacttgc ctggaaagca ctaggaaaag caatggaaaa cgatggtacc
    12541 gcagctttcc atcattacca caaggaagag gagtgagaac atgggcgtac cagaattaga
    12601 agaatataaa ttcgggtttc acgatgatgt cgaaccggtt ttcagtacag gagaaggctt
    12661 gacagaagaa gtgatccgtg agatgtcaag aatcaaaggc gaaccagaat ggatgcttga
    12721 attccgtctg aaatctctag aaacatttaa caaaatgcca atgcaaacat ggggccccga
    12781 cctttcagac atcgatttcg atgccatcaa atattaccaa aaaccaagtg acaaacccgc
    12841 tcgtgactgg gaagacgtac cagaaaaaat caaagataca tttgaaaaga ttggtatacc
    12901 agaagctgaa cgagcttatc tagccggtgc ttccgcacaa tatgaatcag aagtcgtgta
    12961 ccataatatg aaagatgaat tcgaaaagtt aggaatcgtc tttactgaca ctgactctgc
    13021 tttgaaagaa taccctgaat tattcaaaga gtacttttca aaacttgtac cgccaaccga
    13081 caacaaatta gcagcgctga attcagccgt atggtcaggt gggaccttta tttacgtgcc
    13141 aaaaggcgtc aaagtcgatg ttccattaca aacgtacttc cggatcaatg cggaaaacac
    13201 ggggcaattc gaacgtacgc tgatcattgt tgacgaagga gcaagcatcc actatgtcga
    13261 aggttgtacg gcacctactt attcaagtaa cagcctgcat gccgccatcg tagaaatctt
    13321 tacaagaaaa gatgcgtatt gccgttacac aacgatccaa aactggtcag acaatgtgta
    13381 caacttagta accaaacgag caaaagcata cgaaggcgca accgttgaat ggatcgacgg
    13441 aaacctaggt gcaaaaacaa cgatgaaata cccaagtgtt tacttagatg gaaaaggtgc
    13501 acgaggcacc atgctctcca tcgcctttgc aggagcaaac caaatccaag atacgggtgc
    13561 aaaaatgatc cacaatgcac caaatacatc tagctctatc gtctctaaat caatttcaaa
    13621 agacggcgga gaagtaaact atcgaggaca agtaaccttt gccaaaaaca gtgcgggttc
    13681 gatctctcat atcgaatgtg acacgatcat catggacgaa tggtcgaaat ccgatacgat
    13741 cccattcaat gagatccaca acagccaagt ctctttagaa cacgaagcca aagtctcaaa
    13801 aatctcagaa gaacaactct actatctgat gagccgaggc ctgaccgaat ctgaagcaac
    13861 tgaaatgatc gtcatgggct ttgttgaacc attcaccaaa gaacttccaa tggaatatgc
    13921 agtcgaactc aatcgattga tcagttatga gatggaaggg tctgtaggtt aataactatt
    13981 tcattgctcg aaacgttgat attaaagcgt ttcgagcgtt tttttatttg tattttaatg
    14041 gttggctacg tttttggcta cgtttggaat tattcgccca taaattttgc aaatcggtca
    14101 ccagttttct taacagattg tggtgtgaca tgagcataga tattcatggt agttttaata
    14161 tctttatgac ctaatcgttc ctgtacttct tttatcgacg caccactttc aaacaataag
    14221 ctacagtggg tatgcctaaa tccatgtgga gtaatttgag gctccatcgg tgtctttttg
    14281 taaatccagt ctaaccaatc gtttactact tgggggtagt acaacttgtt tgtgtttgta
    14341 gtgaaaagaa actgttttgg tgaattcgtg ttatagccat ataagatcat tattttcatt
    14401 tgttcttgtt gccaaatacg cagttgttta agtgtaaaat catcaagctg aatcgttctt
    14461 gatgaatttt tagttttagg tacttgtaga actacttgat taaactcgtc ttgagcgata
    14521 gttttaccaa ttgttattgt tttattgaaa tagtctatat cttcccattg aagcgccaat
    14581 gcttcgcttt tacgcattcc tgtataagct aataaacgga aaaaagtgta cagtttaact
    14641 gaattatttt ctttagtatt ctgtaaaaac agttgtaatt gatctttcgt gtaaaacttc
    14701 aagggttgtt cttcttcaat ttttcttgga agcaatgttt tagacatagg attatcctta
    14761 cagacttcca ttgctactcc aaatttaaat atttgagcag ttgtttttct caagaaacca
    14821 tattgtttta atgttttgtg ccattcattc acctgttttt ggcaatagct aacacttatt
    14881 ttatccaatc gtaattcccc aaaagcaggt aatatatggt ttttgcaaaa acgttgagca
    14941 acggcaacag aagacggttt tactcttgtt ctgtagttat caatccataa ttcatacaac
    15001 tcttgaaaag ttgtaacatt gattttaaac tcttgttttt ctttaaagtc tacaagtagt
    15061 ctattaagtg ctgtttgcgc ctcagctttt gatttgaatc ttctacgctt tgtacgtata
    15121 tcttttccag tcttgggatc tttccctaaa taagtttcaa atccccaata tttttcgcca
    15181 ttttgtaatt tataactaaa aaatgttgcc atttgattct ctccttactt cattattgca
    15241 ggtagagaag ttatttgaag aatcaattat ttttaaattt atcgtgatta tcagttaaaa
    15301 attttgcgat tatactattt ttctcatatg ggaaattgta ttttttacta agatctgaaa
    15361 taaatttttc tgtttcaaat tggtttttag taattttata aaagaaatcc tcgacagatg
    15421 aatactttga aatatcttta taggctaagt ccatttcgtc taatagctgt tttaaagaat
    15481 caatcattct ttctttttca ccgtatttga aatcaccatt tcttatcttg tcttgaagtt
    15541 tactgttggc tcttttgaaa aatagctctt tagagataga gtgtctttgg ttagcgtact
    15601 cttcaatcag aggattgata ttattagcaa gtatctcatt tagataaatt tcaaaatctt
    15661 ttgagtaata ttttgtaaat atatttttta ttataggatt caataactca tagtctttat
    15721 ctagcgaaaa cgtatcacta tatctttctt gaatgtcttt aaagactttg tgaggtattt
    15781 ctgggaagtc cttaatatat agctcatacc ctatatcgat aaggtatgaa gttatatatt
    15841 cttctaaagt tccccattta atccagtcaa ttgttgaatt agtgatagtt gataataatt
    15901 tcagcttttg tggatttggt aaattggtcc cacgttccca gttggatatg gtcgcacgtg
    15961 gtgaattatc tattttcctt ccaagttctt ccatagtaaa accacatgaa aggcgtaatt
    16021 gtttgattcg ttttcctgct tctgaaggat ttggcttcat cttttttctc ctttttattt
    16081 ttaaagatag tatatcatat ttataaaata aaagtattta aaagtattta ctttttatct
    16141 ggagtatgat actttattct tataaataca aataaataca tttttttacg caatttgtat
    16201 ttatttgtac ttataaaggt agaggagtta tagaataatt aattaaaaag gagaggtttt
    16261 tgtggaagca ataaaattaa tgatttcaga agaacaggag gaaatgtttc taaagcagtt
    16321 ttatcaaatt gctacaaaag ctattgaaaa ggctcaagaa aatgcgggga tgacaaggga
    16381 atatctcaat caaaaagaaa tggcggaata cttaaatgtg agtgaaaact ttttaaaaaa
    16441 tgctgtgaga aatgagggat tgcccgtagt tgaattaggg gcaagaaaat tttattcgaa
    16501 aaaggcagtt aatgagttta tgtttgctcg aatgaaaaga ggggaaaata ttggaagatg
    16561 atgaagtaga aattataaaa aaatgcttta aaaaaagaaa aaaagtgttc ccaaaagttt
    16621 gcagactggg ggaacactca ataataaagt gctgagaaaa ctttatttat agctattata
    16681 tcaaaaaaga aggtgaaaag gtgttttctt ctggaaatgt tgtagttgac aaacttagag
    16741 aaataaattt tgacggaaat gtaatccaca cacatggtac gatcaattaa gaaaaaaaac
    16801 gaaaaaaggt gttgagaagc cctatttgaa tgcaatagtt atcttagcag aaattaccta
    16861 ttggtataga cctaaaaaaa tttttaacga tgatggtcag ctacttggtt atcaaaaaaa
    16921 gtttcttgaa gatattttgc aaaaatcata taagcaatta agcaaaaaaa caggattatc
    16981 agaacgagct ataaaagatg caattgtgta cttagagaaa aaggggatta tcaaaagggt
    17041 ttttagaaat atttattatg agaaaagagc agttacatta tcaaatgtta tgtacattgt
    17101 tttaaatgta cataaattga tagaaattac ttttcctact ttggattgcg aaaaaaagga
    17161 gtatatgccg aaaattcgtc agaggggtat cgaaaaaaag agatatgtct ctttaaaaaa
    17221 aggtagaggt atgtacaaat ttgtatatac gtatacaaag actacttcac agaacatatc
    17281 aaagactact ctcgttatgg aagaagagga tattaatata aagaggattt acagtaagat
    17341 tagtgttctt tatgacgcaa ataacgaaga tggtcgaaaa ttatttcaag tgtatcacta
    17401 tttgagaaac gctaatgtag atacagaaga tatcagaaaa atcattgaat atttatctga
    17461 aaatactcag tatcttattg ctgagtgtat tataaaacaa catgaagcat gcttttttca
    17521 aagaaaaact gaagaagggt tatacgatta tgtaacatat tttttgaatg gacttcagaa
    17581 aagatataaa agtcaatttt tagaaaatgt agagcctata gatcagttca aaaaagcttt
    17641 cgaaatcaaa gagttacctg aaattactat gcataattgg ttgaaaggag aagaatcatg
    17701 attaaaaatc gcttaataga tcaaatgtgg tgtcttgatc aaaatacaga tactctcgaa
    17761 ttaatcgaga gtatctgctt caacacagta gttctcgatt taagagctga aaatgacaat
    17821 tgtgtaactc atatcataat taatcaaaaa atggctcagc agctctctga gagcctaaga
    17881 aaatgggctg aaggagaaaa ctatgaaagc aattaaagaa aaaatcgtta gtagaaaaat
    17941 aaactggtta gcactcagtg tacttgtttt aatgattagc gttgttttta caagtaatat
    18001 tgttgaagct agcattttca attggtttga tgacacaaaa agtcaaacag agtttttgaa
    18061 taattctctt tatagacctt acctaaaaaa atacaatgga gatttcctta gtcagttcgg
    18121 gatttggctt ggatgggctg tggtaaaagg catgtttact gtgactgatt cgattcaaaa
    18181 tatgattcca gatgtgttgg atttgttcaa tttcattgaa agtacagggc taaataatgt
    18241 ttatcaatca gtcataaata caattgtcgt tggattaatg atcctttcat tgatgtttgt
    18301 tggctacaag atgattactg gaaaaggaac aatagattta agatctgttg gaatgaatat
    18361 agtgatgtct gtagcgttaa ttcttttaat gccaacaatg atttctagcg gtattcaatt
    18421 tgccaaaata ttttacaatg atgctactac gattacaaat tcagatgacg gagtcgcttg
    18481 gtcattgata aaacaaggag taacagatct ggcatatatt aataaaacag atcaatactc
    18541 aagcattgat aaaacggagg atcgaaataa gttaacacga aaaaattttc aacagacaga
    18601 tttaacacaa gtgttgacgg ataaagtgat tgataaattg gaaaaagaaa atccagctgc
    18661 ggataatctt cgctatgaat tagttgaaaa ttctaataat gaatttgttg ccacaaagtt
    18721 ttctgataac ttcttatcaa cattttctga tagcttgaaa tcaggttatt atcgatatca
    18781 agcaaatctt tgggggattt cgattgggtt gacagcgttg gcaatcgcct atgtgttcag
    18841 cgcgtttgtg atcattacag caatattaga acttgcattt aaacgtgtgt taggtgttct
    18901 tgtttttgcg acagatattg aaacaggaca acgttcaaaa gttgttttat ccgatatttt
    18961 acaatgttac ttaacagttg gatttcaagg gtttggacta tctatgtttg ctatgtttat
    19021 caatttttta aatgctggac aaggtatctc cacaaatatt tttataaaaa caattgctta
    19081 tatctgtgct gtgtttgtgc tgataaaagg cagtggaaca gtcatgagat actttggtgt
    19141 tgatattgga ctcaaagaag gctatgggca acttgcttct gcttttggta tgggcgcaat
    19201 gctgtttaga aaaggatcaa ctggatttaa tcgtgctaaa ggaagcggaa atggaaatgg
    19261 atcagacagt ggagaaggag aagatcgaaa accagaaaag aatttcggcg aaactctatc
    19321 aaaaaaagct ggcaaaactg gaagagcttt gggatatgcc catgaacgtg gattatcagg
    19381 tttagcttca gatggagcta caatggctag tgaaagagca ataaaaccat ttaagagtat
    19441 gcgtgatatg gctaatgata ccaagaataa gttcaaagaa ggtttagatg atggtacagt
    19501 gtccgctatt aataaaaata gcaaacctat gttagctaaa aataaagaag atgaaactgg
    19561 aaaatatgct gattccatgc caacacgtct ttcggataga aaagatggtg ctaaggttga
    19621 aaatgccgat agaattatgt ctagttctga acgtatgcgt gaagcaatga aaaataatgc
    19681 tgaatcgaat aataatcctg taagtgcaat tcagcaaaaa gttcaacaag atattgaaga
    19741 acgtaaaaat gctatgcacg gtcaagctaa gtctgctgaa gaattaatta atcagaagcg
    19801 acaagaagct aaatacacgc ctgaagcaat gaatcgtgag gaaatgttaa ggaaacgtgt
    19861 agaagggcgt acaggagcta atacggacga aaaagaagcg ttgaccaaag aaagaatcca
    19921 agaagctaaa aactcaaata ccggattaga aaaattggtc aaagaaaatc tacaaaattc
    19981 tacaagtagt caaggtggcc gatcagtaga tgtccgagaa aatattcaag gttcattgaa
    20041 tggtcatgtc ggacggaatg ttgatgtaag agagaattta caaagctctt caaatggtca
    20101 aggtactaag acaattgatg ttcgagaaaa tgtacaaaat tctacaagta gtcaagggtt
    20161 taaatcaatg gatgtaagag agaatgtaca aaattctaca agtagtcaag ggtttaaatc
    20221 aatggatgta agagagaatg tacaaagttc tacaagtagt caaggattca aaacagtaga
    20281 tgttcgggag aacgttcaaa aagatagtgg agaaatgaaa gaaaaaacac aaaaaatcaa
    20341 tatcgttgaa gacagaaagt cagcgaaaaa atttgattca aatcatgaaa cagtgattat
    20401 tgatagtgaa atccgtgaaa atgataaggg atcaaaacca agacgaagat ttacctatga
    20461 agacaacgag ttattcagag atacacttaa tgatcctaat ccgcttttcg ataatctatt
    20521 aaaaaaataa aagggggaat tgtcatgaaa ttaattctaa agattagtac gcatgatttc
    20581 ttagaacttg acgaattatg tgaatcagta aagaacgcaa caaatgaaaa aatcacggtc
    20641 actaattata ttgaactgat gattcaagaa gaattaaaga tgaaacatga gataaaaaac
    20701 aacttgaaat attgttatct agaaaaaagt gaagagataa tccatgaatt aaatggcttt
    20761 taaaaattgt atttgacatg aatttacgac aaggaattag tggggattaa gcgattattc
    20821 tcttccactt tagagaaata atgggttaaa aagccagaat acgtagagca atattgacaa
    20881 cctataaagg agctattgtt gaaaattgaa gtaacaaaaa gataaaggga ggtttacatc
    20941 tatcagatta aaagtgatag tacacccatg aaacctgcaa aagagttgaa cctaatgtat
    21001 atcggtttaa ctctttttat ttgcaaatta aaaaaatatc accgaagtga cgaatgaaac
    21061 tatgaccaaa ttaagcaaga aaatatatct tgcaaataaa gtagtataaa aagatattga
    21121 taaagccaat caaaactttg aatttcaaac gttagataat caaacagata caaaaaatga
    21181 aatcagttct acgcgtacga ttattaaaaa taataaattt tcactagaag aaaatggaaa
    21241 taaaatcaaa taattaggaa gaaaaaacaa agcaattaga aaagcctgca agcaaatttg
    21301 agtaatcgag atccaatttt tttaaggaag tttaacaaaa atatgtaatt ctattatcac
    21361 tattaaagag aaagttggag cggaatataa agaaaagaga aaagtaatta aacgcaaaaa
    21421 aatgtagaac ttaaaaaata taaagaggaa caaccgttaa aattaggaat gatgttgtgt
    21481 aaacattata attgctatga tataaatgaa gtgttaaaga aagcaaattt aaaccaattt
    21541 tgtgaacaga aaagccttag tcactatgac caaaactacg gacgaaacta tgaccaaaag
    21601 taggtactaa attatgaccg aaaataggtc caaaatggat ttttttatga tatcaaaaat
    21661 tatgaaatga ttttgaaaga aaaccagttg gcacagccaa cttagccacc ttcctgtagg
    21721 aaggtgctat cagttttccc ttatgctctt ttctttcttt tttgtttcat atgtcaaatg
    21781 ccattttgaa atgtaccatc ttaagaaatt tatccttaaa aacaattgcg ttattggata
    21841 aaaagatgct acattatctt aaaaaaggaa tcaaatatga tgaatttagt ggctagcata
    21901 tcgtgtgatt aagatacttt atagtgtaag ttgaaggaga aaaaatattt aaaatatact
    21961 tcccatttca gtgggaagta aaattaatct tgttgtttct actagtaatg tatctttttg
    22021 gaaactatgt aacgatgtaa acaagatttt tttcagaaga aaaaacgata aaagttgtga
    22081 taaacgattt aaaaaatagg agaaaatata tcaagcgcat ggtatgaaac gcacatttaa
    22141 aaagattcga ctaactaaaa aaataagttt acaaagcatt gttgtgtatt acaagtgatc
    22201 tatacactga aaaatgatag agaaaatctg atacgtccgc aacaatggac aattgaaaat
    22261 gaaagtgagg aaattggaag aatggctgat gaaaataaag ttgttccgct tgaaacacta
    22321 gtgataaata aggaagagtt tgagcaactt tttcttgatt tttttgttca atatgacagg
    22381 atttatgatt ttagttcgtc actagattta tttgaattag aggcagaaat aatagaaaac
    22441 agtcgagagg agaatggtaa aatcatcatt tcagtagaaa aattcaatga attattctca
    22501 gaaacatttg aaatagatac agattattat caaccacaag aagttttcca atcatttaga
    22561 aatcagatta ttcgctcagg taagaccgta aactgaaaaa caataaaaga aacgttgaaa
    22621 gaataattat tccttcaacg tttctttttt agaatgtttt aatgaccaaa gcagtttcat
    22681 tgtcaggctt aggtaattca tgaaatcccg tatttatagt gctcaattga tcaactaacc
    22741 atgttttact ttttgaattg tagataaatc taaaattaat atcgttatta tcgtgttgaa
    22801 ggggcgtctc caaataatct gctgtatatt catagtcaac gtaacctgct aatacaaaag
    22861 agagtatccc tttatttaat gttagattta atggataatc atacgacttt atttttttca
    22921 acttcatatt gtacatatct tcagccataa aagttgagtt cgtgatttca tcttgggtct
    22981 cattaaaaaa gttatccgaa taatcgctta tttttgaaaa gtctttattg gcaccagcct
    23041 caaaaaattg ttcaactttt tcagtataaa gttgtgctaa cgctcctttt tcaatattaa
    23101 ctttaatatt ttcatgtcta tcaatttgtg tgctgttcag taagggaaga tcagctttta
    23161 gttttatatc gtcttgattt ctttcaattt caattggcaa aatcttttca gtagattcag
    23221 tttctgataa aggaacatct agttttttat catgataata agcttcaaat ccatctggaa
    23281 ccggaaaaaa atgtattggg taattctttt ctgaggttgt tgtactagtt tccgtacttg
    23341 tagaacttgt gtcagaagtg gtacacccgc ttatagttcc gatgagtaaa gcgcaagtta
    23401 gaatgattgc aaatttcttc aaaaaaattc ctccttaaaa ttgaatatgg actaatacta
    23461 gtcccattgt agcataccga atctttaaga ttaataagaa aaaggactaa ttttagtcca
    23521 aaaggtgtgc tattcttgaa agaggaaaaa attattgata aagaaaatgt aatcggtagc
    23581 aatattagac gagtccgatt agaaaaagga attggtcaaa ccgagctgat tagagaccta
    23641 cagcttcgta aaattgctat aactagggaa acgttggtta agattgaagg tggccgccaa
    23701 cacattaagt tggatcaatt gaaagccatc aaagatattc tacaggtgtc ttatgaagat
    23761 ttgcttcaat gactacttgt agtcatttcg tttgaaatta ttatgttaca cccttatgtg
    23821 tcacgaagaa atactggtat aataatgaat gggatatgta acgatagggt atactgttat
    23881 gttgcctaat aaattgtgga tcaaaataca agaatggagg gatatccttg tataaggcat
    23941 atgaattgga ttttacaaat gctgacttaa atgcattctc ctcaagctcg caatcatata
    24001 cacatgtagt aaatcaaata gatcacaacc aaaaatctat taacaagaga atagaaaatc
    24061 tatttgaaag tgaaaatgat ttagttgatt attattctaa ggacagcaaa attctagatg
    24121 cagacgaaat tattaaagat tggtttccaa ctataaaagc agatattttt atatctcact
    24181 ctcatgctga tgaaaaatta gctatacgtt ttgcatcatg gctatttgaa aattttggtc
    24241 ttactgcatt tattgattct tcggtttggg gatacagttc tgatttatta aaaaaaatag
    24301 accaaaaata ttgctataag gaacaaacaa aaacatatga ttatgataaa agaaatgtaa
    24361 caactagtca tgttcatatg atgctttcta cagctttaaa taatatgatt gatagtacag
    24421 aatgtctgtt ttttcttaat acacctaatt caattagttt gagcaatgaa atcactaatg
    24481 aacagaaatt tacgtattcg ccatggctat atagcgaact gacgacagct tcaatagtgg
    24541 aaaaaaagaa tccacgattg gaaagtaatc ctcaaatgag caccgaggat gttagaagca
    24601 ttataaagca ctattcttcg caagaaaatc tgcaaataaa atattcttta aatttaagtg
    24661 aattaactta tttacgaaaa gctgatttga aaaaatgggc tttagatgct gtggaatgca
    24721 ctaaaggaag taatacatta gatattttat ataaaaacac cattttcact aatctctaat
    24781 caatttactg aatcgaaagg aaccgggtag aatggataag aaagttttaa taaagaggtt
    24841 ctctgaagct attgaaaaag gaaatgcagc aatatttgca ggtgcaggat tatcgatgtc
    24901 acaaggatat gtaagttggc cggaactact taatgatcct gcaacagaaa tcgggttgga
    24961 ttctaaaaaa gaaacagact tagttactct ggctcaatat tataaaaatg aaaatggtgg
    25021 atcaagagga attttgaatc agatacttat ggataatttt ggtgaagaat tagaaatatc
    25081 tgaaaatcat cgaatactag caagtttacc tattgaaact tattggacaa ctaattatga
    25141 tcatctaata gaaaaatcaa tccgagaagc ttataaaaac cctcaggtta agaaaaatta
    25201 tactcagtta gcaacaacta atccaaatgt ggatacaatt gtttataaaa tgcatggtga
    25261 tatagatgat gtcagttcga cagtaataac aagagatgat tatgaaaaat atgatgattc
    25321 gtacgcgtta tttaaagaaa ctttaaaagg agatttgtta acaaaaactt ttctcttttt
    25381 aggatttagt tttacagacc ctaatttaga aagaatttta tcagatataa gatgggtttt
    25441 gagagaaaac caaagacctc attattgtat aatgagaaaa atattataga aaaaatttta
    25501 ggttatcgct gaaagccccg gaaatacggg catttcgcag gatatgagaa ctcaatttac
    25561 taccaattta ctactttcgg attgagccgc atatatgctg aaccatactg ctaatacccg
    25621 ccaccccaaa tacggcacat cataaattga atacgacacc gtaaacgcgg cgttcctctt
    25681 tcccgtcatg ggagaacagg acgccgcttt tttatgccca aatagagaaa ggaggcgacg
    25741 ccatgctatt tacttccggc cctgaccggg cgtttgaacg gctgatgcag gaaaagcccg
    25801 gtttcgatca ctacgacggc ggcggggcgg acgcgccgga ggattgcggc acctgccgat
    25861 tttaccgccc ggattggaaa tatcaattct gccagtttgc agagtgtccc tatcagccgg
    25921 gcaagctgac cgactatgca gcggtcaaat tcacagtgaa aggagcgaac aacgctatgg
    25981 cagttttccg tgtggaaaag aacaaaggct atacggtgat gtcaaatcac cacctgcgga
    26041 ataagaacct gaccttaaag gccaagggcc tgctgtcgca gatgttgtcc ttgccggagg
    26101 attgggacta taccctaaaa ggactgtcct atatcaaccg ggaaagcatc gacgcgatca
    26161 ggacagcggt atgggagctt gaaaaagctg gatatatccg gcgtgagcag ggccgtgacg
    26221 caaaaggcaa aatggccgat atggtctata ccatctacga acagccggta ttggaaaacc
    26281 cggtattgga aaatccaaca tcggataacc cggtgttgga aaatccgaca tcggataatc
    26341 cggcgtcgga aaatccaacg caattaaata aagaagtaca aagaactgac ttatcaaaaa
    26401 aagaaaaaat aattacagat ggacaaagta cccattccat tcctatccca tccccgaccc
    26461 ctgcccctat ggagggcgag gcagcggcta cgccgccgga acggaaaagg acaggaaagg
    26521 atgaggctgt acggatttat cgggaaatca ttttggagaa catcgagtat gcctatctca
    26581 ttcaggacag gagcattgac cgtgaacagc ttgacgaaat cgtagacctg atgctggaaa
    26641 ccgtctgcac cgcccgaaag acaatccgtg tcgccgggga cgactaccct gccgagctgg
    26701 tgaaatccaa gtacatgaag ctgaccggcg aacatatccg ctttgtcctt gactgtctgc
    26761 gggagaacac aacgaaagtc cgcaatatca aacaatacct gcgggctatg ctgttcaacg
    26821 cccccagcac catttccaac tactacacgg cccttgtcgc gcacgacatg gcacagcccg
    26881 attggggaaa gcctaaatcc ggcctgccgg actattcctg cggcgagggc gaaagcctgt
    26941 aacgagaaaa ggaggacgac cctatgaagc agggcgcatt gatttttgac gagcgaacag
    27001 accgttacga catccgcttt gatctggccg actattacgg cggcctgcat tgcggggagt
    27061 gtttcgacgt gatgatcggc ggcaaatgga ggcccacccg cattgaaatg gccgaaaact
    27121 ggtatcttgt cggcatccgg gccgacgacc tttccggcct gcgggtgcgg atttgaccta
    27181 tatctacctg cggcgtctgg tggttccgcc ttagacgccg cttttgactt tctgacaagg
    27241 agggatgcga ttgcaggaag aagttactca aaagaccatt gccctgtcca tgaaaacggg
    27301 caagctcacg gctcaagtgc tgcaagcggc gctgaaaaag tacctgcaac accgggccaa
    27361 gggcaaaaac acgctgcacc acggccagca gagcctaaag cagcttaaaa agcatggggc
    27421 tgatctctcc aacattgaga tcaccgaggc caacattgga gcgttcaagc catgcgccaa
    27481 gaaatacggc gtggatttta ccttacgaaa agataagacc acccagccgc cccactacgt
    27541 tgtgattttc aaggccaagg atgcagataa ccttgatctg gcgtttcggg agtttaccgc
    27601 caagacgctt tccaaggagc agcggccctc tatccgcaag gttttgtccg ctgtgaagca
    27661 aaaggcggcg gcccagacca agcagcgggc caaggagaaa atcaaggaaa gggggctgga
    27721 actgtgaagc ctgacgtaaa gaaattgctg atcctgaacc tcccgtatct gatttttgtg
    27781 tacctgtttg cgaaatgcgg ggaggcgtac cggctggccg ctggtgctga cctgtcgggg
    27841 aagctcctgc attttgcgga tggttttgcg gcggcttttg ccaacccgct gccaagcctg
    27901 cacctgtttg acctgtgtat cggtatcgcc ggtgccgtga tcgtgcggct ggtggtgtac
    27961 tgcaagagca agaacgtgaa gaaataccgc aaaggcatgg agtatggcag cgcccgctgg
    28021 gggacggcca aagacatagc gccttacatc gaccccaagt ttgaaaataa tatcctgctc
    28081 acccaaacgg aacggcttac catgaccggc aggcccaaag accccaagac agcgcggaat
    28141 aaaaacgtgc tggtgatcgg tggcagcggt tcagggaaaa cgagattttt cgtgaaaccc
    28201 aacctgatgc aatgctttcc gaccacggac tatccgactt cgtttgtggt gacagatccg
    28261 aaaggcactt tggttctgga aaccggcagg atgttccagc aggcgggcta ccgcattaaa
    28321 atcctgaata ccattaactt ttccaagtcc atgaagtaca acccctttgt ctacatccat
    28381 tcggaaaagg acgtgctaaa gctggtaaat accctgattt ccaacaccaa gggcgagggg
    28441 gaaaagtcag cggaggattt ttgggtgaag tcggaacggt tgttttattc ggccctgatc
    28501 ggctatatct ggtacgaggc cccagcggag gaaatgaact tctcaacgct gctggaaatg
    28561 ataaacgcca gtgaagcccg cgaggacgac ccggagtttc aaagccccgt cgatctcatg
    28621 tttgagcgtt tggagcagaa agaccccgac cattttgcgg tgcgccagta caagaaattc
    28681 ctgctgtccg caggcaagac ccgttcttcc atcctgattt catgcggtgc cagacttgcg
    28741 ccctttgaca tccgggaggt acgcgagctg atggaggacg acgaaatgga gctggacacc
    28801 atcggggacg aaaagacggt gctgtatctc attatgagcg atacggacac gacctttaat
    28861 ttcattctgg ctatgctcca aagccagcta atcaacctgc tttgtgaccg ggctgatgat
    28921 gtgtacggcg ggcggctgcc tgtccatgta cgcctgattt tggatgaatt tgccaacatt
    28981 ggccaaatac ccaatttcga taaactcatt gccaccattc gaagccgtga aatatcggcc
    29041 tctattattt tgcagagcca gtcgcagcta aaagcgattt acaaggacgc cgccgagatc
    29101 atttcggata actgcgatag tgtgcttttc cttagtgggc gcggcaaaaa tgccaaggag
    29161 atttccgatg cgctggggaa agaaacgatt gacagtttca acaccagcga gaaccgggga
    29221 agccaaacgt cccacggatt gaactatcaa aaattaggaa aggagttgat gtcccaagac
    29281 gaaattgccg tgatggacgg cggcaagtgt atcttgcagc tacggggtgt gcgcccgttt
    29341 ttatcggaga aattcgatat taccaagcat ccccggtaca aataccttgc cgacgccgac
    29401 aagaagaata cctttgacgt ggacagattt ttgactatca cgcgccggaa acggcagcaa
    29461 gtggtaacgc aggatgaagt attcgacctg tatgaaatcg acctgtcgga cgaggacgcc
    29521 gccgctgaat aaacagcggc ttttttcatt ccaacaacaa aatcaaaaaa tcattatgag
    29581 ccggaaaccg gcagaaagag gtaaatttat ggcatttttt aattccgcag ttactacttt
    29641 gcagactatc gtgatcggac tgggcggcgc tctgtgcgta tggggcggca tcaatctgtt
    29701 ggagggatac gggcaggaca atccgggggc aaaatcgcag ggtgtcaagc agcttgtcgc
    29761 tggcggcggc gtggccctga tcggtgtcac tctggttccc ctgctgtccg ggctgctggg
    29821 ctgatcctgg cctttgtccc tgtccaaacc cttaactaat cgcctccgcg tcctcccggc
    29881 cagaccggga gggcgcggga aaggaggtgc tacccgtgat tagtgaaatc attgaagaat
    29941 ggataaaagg catcctcatg gacggtatca cgggcaacct gtccgggctg ttcgatacgg
    30001 taaatgccaa agtcggagaa atcgccgccg acgtgggacg aaccccgcag gcatggaaca
    30061 gcggtatttt caatatgctg cacagcctgt cggaaaccgt gatcgtcccc atagccgggg
    30121 ccatactcgc ccttgtcatg tgctatgagc ttatccagat gataacggaa aagaacaata
    30181 tgcacgactt tgacagctcc atgttcttcc gctggatatt caaatccgcg tttgcaatcc
    30241 tgatcgtaac gaacacatgg aacatcgtca tgggcgtatt cgacgccacc caaagcgtcg
    30301 tcaatcaaag cgccggtgtg attatcgggc agacatccat tgattttaac accctgatac
    30361 cagaccttga aagccaattg gaggctatga gcgtgggcgc tcttttgggg ctgtggttcc
    30421 aaacccttgt tgtgggcctc accatgaata tcctttccat ctgcattttc cttgtgacct
    30481 atggccgcat ggtggaaatc tatgttgtca cgtcgctggg gcctatcccc cttgccacaa
    30541 tgggcaacgc ggaatggcgc ggcatgggcc aagggtatct gaaatccctg ctggcgctgg
    30601 gcttccaagc ctttttaatc atggttgtgg tgggtatcta cgcggtgctg atacagaata
    30661 tcggttccgc ttccgacata tccggcgcaa tctggggctg tatgggctat acggtgctgc
    30721 tgtgcttctg cctgttcaag accggcagta tatcaaaggc cgtattcggg gcgcattgat
    30781 cccaaaatcc aagcatacac aggaggaact tgtttatttc aacgtacaac atcatttacg
    30841 ctgacccgcc gtggcggtat gactgcaaaa acgtacaggg cgcagcggaa aatcactatt
    30901 ccaccatgag cattgacgag ctgtgcgccc tgccggtgga acggctggcg tccaaagact
    30961 gcctgctgtt tttgtgggcc acattcccca tgctgccgga agctctgcgg ttaatcaaag
    31021 cgtggggctt ttcattcaag accgtggctt ttgtatggct gaaacagaac cgtaaaagcc
    31081 ttacatggtt ttacgggctg ggccgctgga caaggggaaa cgcggaaatc tgcctgctgg
    31141 caacacacgg caagccgaag cgtcgttctg cctctgtcca tcagtttatt atcagcccga
    31201 ttgaacaaca cagcaaaaag ccggatgtga cccgtgaaaa aatcgtagag ctggcgggcg
    31261 atttgccccg cgtggagctg tttgccagac agaaaacccc cggctgggac gtgtggggga
    31321 acgaggtgga atgtgacctt atcctgacgt gaaaggaggt gccaaatggc ttatgtaacc
    31381 gtccccaagg acttaaccca tgtgaaaagc aaggttgtgt ttgggcttac caaacggcaa
    31441 ctgatctgtt tttccggggc gctggtgatc ggcgtcccct tatattttct cacccgtgac
    31501 tatcttacca acagcgcggc ggccctgctc atggtatttg ccatgctgcc gggctttttg
    31561 cttgccatgt acgagcgtca cggccagccc cttgaagtgg tgattatgca gatcatccag
    31621 tgctgcttca tccagccaaa ggagcgtccc tatcagaccg acaacaccta caccgccctt
    31681 gtgcggcaat accagatgga acaggaggta aaggccattg tccaaaaagg aaatcccaag
    31741 agaaaccgaa aaaacaaagc tgacccgcgc ccagcgaaaa gaaattgacg cggtaatccg
    31801 taaatataag ggcgacggca ggccccacac ggcgcagcag agcatcccct acgaggtcat
    31861 gtacccggac ggcgtgtgcc gggtatcgcc cggcgtcttt tccaagtgca ttgagtttgc
    31921 ggacatcagc tatcagcttg cccagccgga cacgcagacg gctatctttg aaaaactgtg
    31981 cgacctgtat aactatgtgg acgcctccat tcatatccag ttttctttcc tcaatcggaa
    32041 agttgacccg gtgcagtacg ccaagagctt tgagatcgcg ccgcaggggg acgacttcga
    32101 cgacatccgg gccgagtaca ccggcattct gcaaaagcag cttgcaaacg gcaacaacgg
    32161 catggtaaag accaaatacc tgacattcac catcgaggcc gaaagcgtga aagcggcgcg
    32221 agccagattg aagcgcatcg gctttgacct gttaggctat ttcaagagca tgggggccgt
    32281 agcccatgtg atggacggct gggaacggct gaacctgctg catggcgtgt accacccgga
    32341 cggcgagata ttcaattttg actggaagtg gctggccccg tccggcctct ccaccaagga
    32401 ttttattgcc ccgtcctccc tgtgcttcgg caatgcaaag acattcggca tgggcggcaa
    32461 atacggcgcg gtaagtttcc tgcaaatcct gtccccggag ctgtcggacg atatgctggc
    32521 cgacttcctc aatacggaaa gcggtgtttt agtcaatctc catgtgcagg ccattgaaca
    32581 gaccaaggcg atcaagacca tcaagcgcaa aattaccgac cttgacgcta tgaagattgc
    32641 ggagcagaaa aaggccgtcc gcagcggtta cgatatggac attcttccca gcgaccttgc
    32701 cacctacggc gaggacgcca agaagctgct gacaaagttg cagacccgca atgaacggct
    32761 gttccagttg acgttccttg tcctcaacgt ggccgacacc aagcaaaagc tgaataacga
    32821 cgtgttccaa gccgcaggcg tggcccaaaa gcataactgt ccccttgtcc ggctggacta
    32881 ccagcaggaa cagggccttg caagcagcct gccgctgggc gtcaatcaga tcaagataca
    32941 gcgcagcctt acgacttcca gcgtggccgt gttcgtcccc tttgtgacgc aggagctttt
    33001 tcagggcggc gcggccatgt attacggcat caacgccaag tcccgcaaca tgattatgct
    33061 ggacaggaag caggcccgtt gccccaatgc cttgaagctc ggcacccccg gcagcggcaa
    33121 atccatgagc tgtaaatccg agatcgtcag tgtgttctta acgacgcctg acgatatttt
    33181 tatttcagac ccggaggccg aatattaccc ccttgtcaaa cggctccacg gacaggtaat
    33241 ccggctgtcg cctaccagca aggactttgt gaacccgctg gacatcaacc tgaattattc
    33301 ggaggacgat aacccgctgg ccctgaaatc cgactttgtg ctgtcgttct gtgagcttgt
    33361 catgggcggc aagaacgggc tggaagccat tgaaaagacc gtgatagacc gggctgtgcg
    33421 cgtgatctac cggccctatc tggcagaccc ccgcccggag aatatgccga tcctgtccga
    33481 cctccacaaa gcgttgttag atcagcatgt cccggaggct gaccgggtgg cgcaggccct
    33541 tgacctgtat gtgtccggct ccctgaacgt atttaaccac cgtaccaacg tggacatcgg
    33601 caaccggctt gtgtcctttg acattaagga gctgggcaag cagctcaaaa agctggggat
    33661 gctcattgtc caagaccaga tatgggggcg cgtcacggcc aaccgaagcc aaggaaaggc
    33721 cacatggtat tttgccgacg agttccattt gcttttgaaa gaggaacaga cggcggccta
    33781 ttctgcggag atttggaagc ggtttaggaa atggggcggc attccaacag gtgccaccca
    33841 gaacgtcaaa gacctgcttt cctccccgga aattgaaaat atccttgaaa acagcgactt
    33901 cattacgctg ctcaatcagg cgtccgggga tagaaaaatc cttgcggaac gcttgaattt
    33961 gtccaccgaa cagcagaagt acatcgacaa ttccgaaccc ggcgagggcc ttttgatctt
    34021 tgaaaacgtg gtgctgccct ttaccaaccc catcccgcac aacacccagc tttacaagat
    34081 tatgacgacc cgcttaaacg aggtggcggg agtatgaccc ggcgacgcca caaaggaggt
    34141 gaaccaccat gaaagagctg aaagccaagg cgaaagtgac gcaggccatg acccgcgacg
    34201 ggctgacgct ggaaaatcag gccaccggcg aggtggagaa catttccagc cgggaggccg
    34261 aacaggattt gtccgcgccg gggccgggcg gcaccgccga taagctgctg gaacgggccg
    34321 acgccatcca tgacggccat aaggccaaga aagccgcgaa gcaggccggg gctgtggccg
    34381 ccgaggggga cgctgccctg caccggccat ccgcccggct ccaactgtcg gaggaagaac
    34441 gggccgaccc ggatttacag ccctatatcc gaaaatcgga caaacgggcc gataagctgg
    34501 ataaggcccg cgccgccatc cccaagaagc gcgtcccggt caaggaaacc gtctttgacg
    34561 aggcaagcgg caaagcaaag accgtcctgc actttgacaa acaggacaag gggcctccct
    34621 ccctgaaacc caatccggca ggccgtcctg tttccgaggt ttttctattc ggccacggga
    34681 aaatccatga agtcgagcat gaaaacgtgg gtgtggaggg cggccataag ggggaggaac
    34741 ttgccgagcg gcaggccgga aaagccatcc gcagcaccat ccggcaccac aggctgaaac
    34801 cctactggga cgcggaaaag gccgagcgca ggctattgtc tgccaacgcg gagtatttct
    34861 accagaaatc tttgcgggat aacccggaga tcgcacaggc ggccagcaac cccatttccc
    34921 ggttctggca gaaacagcag atcaagcgcc agtacgccaa ggccgcccgg acagcgggcc
    34981 agaccgcagg cgcggcggca cagggcgcgg ccaagacagc cggggcctcc acgaaagcgg
    35041 ccaaggccgc agccaaagaa agtgaacggg cggcctcctt tgtggcccgc cactggaaag
    35101 gggcgctggc cgtccttgtg ttggggcttt tgatgctgct tatcatcggc ggcttacagt
    35161 cctgcaccgc catgttcggc agcgccggaa gcggcatcac ggcgtcctct tacttttccg
    35221 aggatagcga tatgttggcc gccgaggacg cctacgcgga gctggaagcc gagctgcaag
    35281 actatctgga caactacgag gccacccatg actatgacga ataccatttt gaccttgacg
    35341 agatcagcca tgacccctat gtgctgattt ccattctgtc ggcgctccat gacgggatat
    35401 ttaccatcgg ggaggtacag ggtgatttgt ccatgctctt tgacaagcaa tatatcctga
    35461 cagaaaacgt cgtggtagaa acccgttacc gcaccgaaac cgatacatgg acggacgcgg
    35521 agggcaacac ccatacagac acctaccaag tgccgtatga ctattacatc tgctacgtca
    35581 cgctggaaaa cttcgacctg tcccatgtgc cagtctatat catggacgag gaaacgctaa
    35641 gtttctattc cctgtatatg tccacgctag gaaaccggcc tgatctgttt tccggcagcc
    35701 agtaccccaa cgcctccacc ctgacgccgc cgacctacta cgacgtaccc ccggaggctt
    35761 tggaggatgc cacctttgcc gccatgctca aagaggcgga aaaatatatc ggttatccct
    35821 atgtgtgggg cggcagctct cccagcacca gctttgattg cagcggcttc atttcgtggg
    35881 taatcaatca tagtggatgg aacgtgggac ggctgggggc gcagggccta tataacatct
    35941 gcacccctgt ttccagttcg caggccaagc ccggcgacct tgtatttttc aagggaacct
    36001 acgacacccc cggcgtgtcc cacgtcggcc tgtatgtggg caacaatgtg atgctgcatt
    36061 gcgggaaccc gatttcctac acgaacctta cttcaaacta ctggcaatcc catttttaca
    36121 gttacgggcg tttaccttaa cgccagaaag gagctttcaa ttatggcaac caaacttgac
    36181 cgcatcgaaa aggacatcca gaaaaccaag tctaagatcg cggagtttca gaaacagctt
    36241 cgggagctgg aaacgcagaa aaccgaacag gagaatttgc agatcatcca gcttgtgcgc
    36301 ggcatgaaca tgaagccgga ggaatttgcc gcgttcttac gcagcggcgc aatgcaggcc
    36361 gcccctgccg caacccctta ccatgaacag gaggacaatg cccatgaaga ataagaccag
    36421 acggatttcc cgtattctcc ccgcacttct ggccgtgatg ctctgcgtca cggcctttcc
    36481 cgttaccgcc cttgcaggcg gcaatgaccc ggcaccggcc ccgctgccgg aggctacaac
    36541 cgaacccgct acgggcggtt tggagcctga aacagacgaa accggcaccg ccacggacgg
    36601 gacagaaacc gaggccgaaa aagataccgg ccctctgacc ggcaaggaca tcaccgacct
    36661 gttttccgcg ctgttcggtt ccaaggtgag cattgccgcc acggacgacg gcatccagat
    36721 caccaccggc accgacaaaa aagaacctga acagaccggc accgtcacca ccaacggcgg
    36781 caggctgaat gtccgcaccg gcgcggggct tgacaagacc gcgttcaccc agcttcccaa
    36841 tgggacgacg gttgaggtag tcggcacaga cggcgactgg attaaaattc tcttgccgga
    36901 gcgcatcggc tatgtccatt ccgactatat gaccgtcagc gaaaaggaag tagcggctac
    36961 cggcgagggc ggtttttccc tctccattga cccggaggaa attgcttctc tgctggaact
    37021 gttcaatggc ggcggggcca gcgccgccct gtccccggac gggaacctgt cactgattga
    37081 cgacatcggc agcgccgcga aaaatggcaa gcagtttatc accgtggaaa ccaaaaacgg
    37141 caatgtgttt tatctgatta ttgaccggga cgacgaggga aaagaaactg tccatttctt
    37201 aaatcaggtg gatgaagccg atctgctgac gctgatggag gacggggaaa ccgtcacccc
    37261 cgctgctgtc tgctcctgta ccacgaaatg caaggccggg gctgtgaaca cgaattgccc
    37321 ggtatgtaaa accaacctga ccgagtgcag cggcccggag ccgcaggaac cccagccgga
    37381 ggaacccgaa gccccggagg aagaacccaa gggcggcgcg ggcggcctga tcgtgttcct
    37441 gctggtggcg ctggcgggcg gcggtgcggc cctttactat ttcaagttca aaaagcccaa
    37501 ggctgaaacc accggcagcg acgatttggg cgagtatgat tttggggagg acgaggattt
    37561 ggaggacgag gaacccgaaa ccgagtttga cccggaagct gattttgtga gtgaacagga
    37621 ggacgaggaa tgacatataa acttgtaatc gcggaaaaac ccagcgtggc ccgcagcatt
    37681 gcgggcgtga tcggggccac ggagaaacac gacggctatt tggaggggaa cggctatctg
    37741 gtgagctggt gcatcggaca tctggtgtcc tttgccgacg ccggacgcta tgacgagcgt
    37801 ttcaaaaaat ggcgctatga ggatttgccc attctcccgg aaacatggca gtacatcgtc
    37861 cccgacgaca agaaacagca gtttgacgtt ctctgttcgc tgatgcagcg ccccgacgtg
    37921 accggccttg tgtgcgccac cgacgccggg cgcgaggggg aattgatttt ccgtttcgtc
    37981 taccagatgg cgggatgcca aaagcccttt gagcgccttt ggatttcctc tatggaggac
    38041 agtgctatta aggacggctt tgcccacctg aaaccgggcg gcgactatga tccgctgtat
    38101 caatcggccc tgtgccgggc caaggccgac tggctgatcg gcattaacgc cacccggctt
    38161 ttttccgtcc tgtaccacaa gaacctgact gtgggccgcg tccagacgcc gaccttaaaa
    38221 atgctggtgg acagggacgc caagattacc gatttcaaga aagagaaata tcacatcgtc
    38281 catatcacgg cgggcggcgc ggacgcggta agcagccgct tttccgacgc tgccgaggca
    38341 aacaccgtca aggcggcttg tgcaaaagcg caggccgttt gcgtttccgt gacgcgggag
    38401 aaaaagacgg aacagccgcc caagctctat gaccttacca ccttgcagcg ggaggctaac
    38461 cggcttttcg gctataccgc caagcagacc cttgactatg cccaggcact gtatctaaag
    38521 aagctgctga cctatccgag aacggatagt caatatctta ccgacgatat gctgcccgcc
    38581 gtggaaagcc ttgtgtccgg cctgtgggag ctggtgccgt ttgccaaggg cctgaacctt
    38641 tccccgcagt ttgaccgcat cctgaacagc aaaaaggtgt ccgaccacca cgccattatc
    38701 cccaccgctg aatttgtgaa gcagggcttt ggcactctgg ccgagagtga aaaaaagctg
    38761 ctgtccctga tctgctgcaa gctcttatgt gccgtggccg ggccgcatat ctatgaggcc
    38821 gtcaccgcca catttacctg tgccgggcag gagtttaccg ccaagggcaa gaccgtcctt
    38881 tcccccggct ggaaagagat tgaacgccgg ttccgttctt ccttaaagac cgacgccgac
    38941 gaggacgccg aggcggtgcg ggagctgccg gagctttgcg agggccagac ctttgcagac
    39001 gtggccgcct ctgtcaccga gcatttcacc acgccgccca agccctacac cgaagatacg
    39061 cttttgtccg ctatggaacg ggccggggcc gaggatatgc cggaggatgc cgagcgcaag
    39121 ggattaggca caccggccac ccgcgccgcc attctggaaa agctggtgca gatgggcttt
    39181 gtccagagaa aaggcaagca gctcattccc accaaggacg gcatcaatct ggctgtggtg
    39241 ctgccggagg cgcttacttc tccccagctt actgccgaat gggaaaaccg gctgaccgag
    39301 atcgccaagg ggcaggccga tcctgacgaa tttatggacg gcatcgagac gcaggcgcgg
    39361 gagctggtgc agacctattc ctgtatcagt gaggaaaagc agaaattgtt tcaggccgag
    39421 cgtgttccta tcgggacgtg tccccgctgt ggtgaggctg tctatgaggg caagaaaaac
    39481 tactactgcg gaaaccgggc ctgccagttc gtcatgtgga agaatgaccg attttttgag
    39541 gaacgcaaga aagcgttcac cccgaagatc gccgctgcgc tgctcaaaac cggcaaagtc
    39601 aaggtaaagg gcctctattc cgtaaagacc ggcaaaacct acgacgggac ggtgcttttg
    39661 gctgataccg ggggcaagta cgtcaactac cgcattgaac acaggagcta aaggacagta
    39721 acacagcaag catagggagt gtggctacac tcccggtaaa atcccccggc cgcgtccctg
    39781 ccgggccggg gatttttgct tgttggggaa gtccccaacc ccctattttt tgaaacagaa
    39841 cagagaaagg agtgaccgcg tgaacgaagt attttctatc caagtccata accggcagtt
    39901 tttggaacag ggcaaacaag gcgtctggct ggatttgccc accacaaccg aaacgctgca
    39961 agccgccctg cgggatgttg gcattactgc cgacaatccg caggattttt ttatcaacgg
    40021 gtattcctgc ccggaggaca gacaccttgc cattccctat gacatggtgc tggccgccga
    40081 cgtggacgag ctgaatttcc ttgccgcccg gctgggccag cttgacgccg ccgagatcgc
    40141 agagctgaac gccgccctgc aaaatccccg tggcggcttt gagaatatcg gccagatcat
    40201 cgactacacc gaaaatgtgg attactatgt gcatcttccc gacgttaggg gggatggaca
    40261 gttgggcgac tactacctga accgttccgg catggtggat atgccggagg aatggaaagc
    40321 cgggattgat acggcgcagt ttggacgcca cattgcccag caggaacaag gcgtttttac
    40381 ccagtacggc tatctggtga gaagcggcga cgaatggcag cgcgtccatg agggccagcc
    40441 ggtgccggag gaataccggg tgatgcacta cccccagccg gaagctgacc gggaggaacc
    40501 gcaggcccag cagccggagg catccgaaag ccccgacaaa gcgccgcccc cggttatccc
    40561 gatcatgctg gacggcatga acagcaaaga acgcatgaaa gtgattactg accgtctgga
    40621 aaccggcgta caggagcttt ttgaaagtag ccgctatatg gcttacttat ccgctatgtc
    40681 caagatgcac gattacagtc tgaacaatac gctgctgatc gccatgcagg gcggttcgat
    40741 tgtggcgggc tataacaggt ggcaggatga atttgaccgc catgtgaagc ggggcgagaa
    40801 aggcattaag atactggccc cggccccgtt caaggttaag cagcagatgg agaaaaccga
    40861 cccggccacc cagcagcccg tgatcggcgc ggacggcaag cccgtgaccg aagaacagga
    40921 agtgacggtt ccggccttta aggtggtgac agtctttgac atcagccaga ccgagggcaa
    40981 ggattttccc atgccctata tcagtgaact taccggcgac gtgcagcagt atcaggattt
    41041 ctttgccgcg ctggaacgga catcacccta tcccataagc attgagccga tttcagacgg
    41101 ggccaagggc cgctgcttct acgcaaaaca gcgcattgcc atcaacgagg gcatgagcga
    41161 attgcagacc ctaaagaccg ccatccatga gattgcccat gccaagctcc acgccattga
    41221 ccgggaggcc cccgccgagg aacaggcggc ccggccagac cgcagcaccc gcgaggtaca
    41281 ggccgaaagc gtggcctata ccgtctgcca gtattacggg ctggacacgt cggactattc
    41341 ttttggctat gtggccgatt ggagcagcgg cagggagtta tccgagctga aagcctccct
    41401 tgaaaccatc cgggccacgg ccagcgaatt gataaccgag atcgacggcc attttgccca
    41461 gcttcagcag gagcgcgagg cccggcagga acaggaggcc gtcacggttg acgttacccc
    41521 ggaggcagcg gccccggcgc aggccgagga agaacaggcc ccggcccttg atccggcagc
    41581 cgagccgctt gtgactgtgc tatggagcga aagcccccag ctaaaggacg gccagcaaat
    41641 gccgttgcat gaggccgacg cgctgtttgc ccgtctggat gcagcatatc cggcagaggc
    41701 aggctatgac aaaaccgcgt tccgcattga ctgtatcttt cagggcgagc cggacagcta
    41761 cgaggggcgg caggattttg gagataggga cggttccctg atcgaacata tccagagcta
    41821 ccaccaattt tacgcgcagg acgaaaactg gaaaaagcat gtaatcgcta caaccggcat
    41881 agagggctgg gagcaggaca aggcccatcg ggatatgctg ttaggcgagt ttgtccccta
    41941 tatgaagctg cattgcagcc ttgcccaaat ggaacagacg gcgcagggcc gcttacagtc
    42001 cggggaaacc ctgacgccgg aggaaacggc ctatttgggg gcgcttctct cttatgtgca
    42061 ggagtgccgc cccatgctca atcagggcca gtatcagttg ccggagccgc cgaaactggc
    42121 tgacttcgac cagagcttgc aggactacaa agcacaggta caggccgaga tcgcgcagga
    42181 ggccgccgca gccggtatga ccgtggagga atacgcggcg gctggctatg aagcacccca
    42241 acaggacacc ttttccatct accagcttcg aggcggggag gaaacccgcg actatcggtt
    42301 tgagccatac gagcgtttac aggccgcagg gctggccgtg gacagtgcca actatgacct
    42361 tgtttatacg gcaccgctgg ataaaagcac gtctttggag gatatttacc gcacattcaa
    42421 catcgaccac ccggcagatt ttaggggaca cagcctttcc gtttccgacg tggtggtgct
    42481 gcaccagaat ggacaggaca ccgcccacta tgtagacagc ttcggctata tggaagtgcc
    42541 ggagtttttg cgggaaaatc ccctgcgtac cgccgaactg tctacggagc agaacgaaaa
    42601 catgattgac ggcattatca acaatacgcc gcccgaaccg cagccggagg aacccgaaca
    42661 gctatctttt gaggatgtgg cagttgcttc cggccagaca caggaggaac ccccggaggc
    42721 tgcgcccccg caaacggctg tccgctatta tcccatcaat gagggagccg cccgccgcgc
    42781 caaggaagcc atgagctttt ctgactaccg gcccggcagc gccacggcgg aataccggca
    42841 ctatgtcgat caggccgtgg aaattgcgga gcgccagaaa aagcgtgtgg agccagagta
    42901 tcacgaaaag atagacagcc tccttgacac ctacgcccgc aagctggccg agaacatgaa
    42961 taagggctat gagattaccg cccgcgtccc ctctgtcctg attgccgggc cgtccaattt
    43021 cccggtacgg gcgaaagaaa agcagaacgc cgccagtgac cgcaacatgg aggaatttca
    43081 gtacattcag ggcttgcttg acaaaatccg cagcaccggc atgggtggta tcagcgccga
    43141 cgatccgcag gccgtttcca agctggaaaa gaaactggaa aagctggaag cgtcgcagga
    43201 gttgatgaag gccgtcaatg cctactaccg caagcatggg acgctggacg gatgccccca
    43261 tctgatcgaa agaggcattg aaaacctgaa agcggatatg gcgtcgggct ggcactatga
    43321 gaaaaaaccg ttccagtcct ggcagctctc caacaataac gccgagatac gccggttaaa
    43381 gggccgcatt gaggaattga cccgccaaaa ggaggcggcc tatgtgggat gggagtttga
    43441 cggcggcact gtggagatca accgggtggc caaccgcctg caaatcttct ttgaggggaa
    43501 gccggatgct gctgtacgcg acgagctgaa aagcaacggt ttccgctggt cgcccaaggc
    43561 cggggcatgg cagcggcagt taaacgacac cacaatccgc gtcgctgacc gtatcaagtg
    43621 catccagccc ctttccggcg aaaagcccag cgccttacag cttgcggccc gcagggagaa
    43681 agaaaagccc tctatccggg cgcagctcaa cgcggccaag accgaacagg ccaagcagcc
    43741 accggcgcgg gaaaaatcaa agggattgga ggtagagtaa atgcagaagt ttgaaaatgt
    43801 ggacgttctg gccgcgctgg aacagatcat gcggcagaac accgcgtttt atcaaagtga
    43861 ctttggcatt gacaaagaca ttatcaggcg ggatgccgcc agcgatcagg ccgcagacaa
    43921 gaccctgctc tggatgtccc ggccctccgg gacgtactgt ttccgggaac gtgatgtttt
    43981 cctgaaagac acccgacagt acaacacatg gaaattttac ggggagcaga cccgtgacaa
    44041 gatactggcc tacgcggtgg agctgaccgg cacacagggc ggcactatcc ggggcaatct
    44101 ctatgagctg gactatccgc agcatttccg gcacgtcatt gaaaccgccc agccggtgag
    44161 tgtgaaccgg ctcttttatg agcatggcac ccgtgacatc ccggagagcc agcgttttga
    44221 cggaagccct gaccgggtat tgggaaactt tttgtactat gaggcccagc cccatgaccc
    44281 ggctgtgctg caggaggcgc tacggacgga gcagcacagc cgggggcggg ccgtccccgg
    44341 cgatttcaaa gtccacgtca ccgctttgca tgacagccgg attgaaaccg aggcccggcg
    44401 tattgtggac agcctgaaag atctgtccgc gcctaacagc cccaataaaa cgcatttcat
    44461 ggtggagatc tccccgcact ttgcggcgat tgcttccacc aaggataatg accggctctt
    44521 tgccatgctg ccctataaat ccctgtgttt taccgggatg aaaggcaggc atggcgtgta
    44581 tgccgtgatt aaccgggacg agcgccggga tgtgagtatt cgcaggcccc ggccctctat
    44641 ccgcaagcag ctatccgaca gcaaacaggc cgccagccca aaaaaggcgg cggccagaac
    44701 caaaaagaat gaattggagg tataaggaat gatgcacttt accgtggagg aagaaaacct
    44761 gatctgtatg taccacaatg cagaccggcg cagaacgata aacaggctca ccgccgtcat
    44821 gccggttatg gatggggata tgcgggcgca ggcccagcag accctttcca agctggaacg
    44881 catgacggat gccgactatg acggccagaa gttccacttc acagacgaat aacgaacagc
    44941 agacgccggg cgcggcggcc atgtggtcgc ttgcgtccgg cgtcttttct ttttgcctat
    45001 tcctacgcat ttagaacccg gtattgtcgg ggataggatg aagtattcgc ttgcccctgc
    45061 aaacatgcgg gagaagcctt gcagcgggcg gttttcaatc ccttaaatgc gtaggttgca
    45121 gctataatta gacccctgaa acagatatag ccgcgcagcg ggtgtatctg tttcaggggt
    45181 gtgcaggtga tagccgcaaa gcggcgtaag agggtgcagc cctcttgccg tctatctctg
    45241 ttccagcggg aagctcggca atgcttccag cagtttcagg gaaatgcgct gccgtatatc
    45301 ttcgtcaatg actttcttct ttttgccgtt tgcctgtctg atctccaccg tggaaagctc
    45361 gttgatgtag tcagcataat gggccaacac tttttccgtg gcccacctct caccggcaac
    45421 ggcggctttg atcgtttcat agtccagcag cttttcttgt ccgtccatcc tgataccccc
    45481 gtcagactga ttttttctat gataccatat tcggaagcat ggaaccagag aaaacggcgc
    45541 ttttctgctg gtaaattcta cgcatttaga acagcacttc ggcggggata ggataaaaca
    45601 cccacatacc ccgctgacca tgccggaaaa gccttgaaat ataagggctt ttacagctct
    45661 aagtgcgtag gtttccagta tcttttccgc tggcgctcgg cctctttgcg gcggcgcatc
    45721 cgtttggagc aggccgcgca gtatttggcc cggttagact tcggcgtgaa cgtggccccg
    45781 cactcacagc agcgtttcac ttcgtcccgg tctttggtga tctcggcata cagggccgca
    45841 tccagcggga ggacagcggc cttaaaccag cggcacagaa gcgaatagga aatgctctgt
    45901 acgcaaatac attcttcgcc gtcgtccagc aacaggcagt tgccgtcaca atagttgcag
    45961 cactcatgcg tcagcttccg ggccttgcga tattgagggt aattcattcg tggaatactc
    46021 atagctcttg cgtccattcc tttcccggcg tcatacgcaa aatgccgtcc acattctgct
    46081 tgatgatgcc gtattcctgc atctgctttt tcgcttcgcc gtacttctca tacagccgtt
    46141 ccttttcctc ggccaatcgc ttgtactcgg ctttcagggc gtacagatcg gggagctttt
    46201 tcacaccctg tccctttagg gcctttgccg cagcttcata caaaatcaac gtgctttcat
    46261 gctcacgccg gaattttgcc ttatccgctg cattgcggta ttccatagcc acgggccaga
    46321 gctgcttgta ggtagaaata ttctttatca gcaccgccat atccgcaagc cggtgttcca
    46381 tagctttgag ggtagcggcg gcctcgtcgc tggcggcggt gatctcggcc actttgcttt
    46441 ccaaatccgg gtaggtgtct atcccatgtt cagtcaggaa attcaaagtc tttgcggcct
    46501 gcttcaaatt gtggagcttc gcccacctct catagcctgc cgactgctgg gccttaatgt
    46561 tgttttccag atcaatccgc aaagaaatcc ccttgcgctc tttgggcgct ctggtgataa
    46621 cgcggccttt gatacgctct ttgatggctt cctcggtgta ggcttccccc aatgtcttgc
    46681 agcgggtaaa gcgttcctgt ccgggagcgc ggaaagaaat aaactttccc ggcttgatct
    46741 catagccctg cgcctgcatg agccgcagga aatcatcaaa atcttttgcc tgcgggatag
    46801 cggcgtcaat ggctgctttg agcttcgctt tccagctcgt ccctttccgc tgggcgtccc
    46861 actcggcata gctcttgccc ttactctggc cgggcttcac cacggacaat ccgttttcct
    46921 tgcacagcct gtcgctggtg cgccggatat aggcatagct ctgtttgttg gaaatgtact
    46981 tgcgctgatt taccatatcc acggcacaga aaataatgtg attgtggacg tggcccttat
    47041 caatatgggt agtcagcaca tagggatatt tcccttgcag cacttcctcg gcaagctgct
    47101 tcccgatctc atgggcctgt tccggcgtgg cttcgccggg ggcaaaggat tgtatcaggt
    47161 ggtggcccag attattgccc ttttggtatg cctgcgccag cagcatttca aattcaatgt
    47221 ccgctgtttc ataagagcag gcaaaggagg ccaccagcag cttgccgtca gttttgtccg
    47281 ggttctcgat gtagtcaagg gcttttttca gcgttgactt gataggatgt atctttgtaa
    47341 ctgccatatc tgcgccagcg ccccctttat atcctcgatg tcctgtgcgt acaccggccc
    47401 cataccgttc agcctctttg caatctgatt gacgttgacg ccgatcttct gtatctcggc
    47461 ggtctgcgcc cggatgtcgc tggtgtccat gttgacgata tagccgtcaa tgagcatctt
    47521 ccgggcgtag gctgaaaagt tcttcgtatg cagcagcgcc attttctgtt caatcatagc
    47581 ccgttcctcc ggcgtcacag ggacgcgcag cacgattttt cgctttctgt ttgccatgct
    47641 tcaccgtcct ttccattcag gggtttgggg atttccccaa caagcaaaac ggacgcggcc
    47701 cggcagggac ggggcaggcc gtttttccgg gagtggctac actccctatg cttgctacgt
    47761 tactgtttct ccactaacaa gacgtttcca aagccccaaa ctacccgcaa aatagccctc
    47821 tggaaagaaa aaagtgcaaa aaaatagaag ctacgctgtg cagctcccgc taaaagtaaa
    47881 acagaggatg ccagttacac atcctccgtt tcattcttct tcggcttttc aattagtatg
    47941 gcgctgtcaa tcgcgccctc gatgatcggc aggtattctt cggggcagag tttcagcttg
    48001 tggctgaccc tttgccgcag ttcgctttcc tcccgcatga tctccgggtt aaagtagcgt
    48061 tccacaggaa gcccgcaggc tttaataagc tgtatgacaa ccggcagact gggaatggcc
    48121 cgtcgttttc gatgttggca agatagcgcc agtcaatatt tattttctct gccattgctt
    48181 tgcgcgaaac gcgctttgct tgccgggccg ctttcacatc cgcgccgaaa gtttcaaagc
    48241 cgggacaatc ttcaatattc gccatatcgc acctcccact tacattgtat atttcatact
    48301 ctgcccgtgg aatgttggta tatgcacctt tcttaaagtt tatatttcac attttgtttc
    48361 ttttattctt cgagcaaaag aattataatg taccctgtgg aggtgtacta tggactacat
    48421 gacgttgaaa gaggcaggcg agaaatgggg tgtgccccca cgatggataa actactattg
    48481 tgctgcggga cgcatccccg gcgctgtaaa gatggcgacg atctggctca ttcccaaaac
    48541 tgcggaaaag ccgattgaca ggcgtacaaa gaaaggaaag gcggttactg aatagtataa
    48601 tgaaaccggc gcattttgga tatggttttg aagagagaga aagcatggta ttttgtcacg
    48661 gaaaaactat aagatgatag atggcaggct gctccagacc gataaaaagt attctcatct
    48721 gaaacagaaa gaaaagattt acacatggat gtatgaagaa gcgaaacttt atcatgacag
    48781 aaatggaaaa tgcccgaaac aaagacgagg aagctgctgc tgtatcagcc gtatatggta
    48841 gaattgaaaa ggccggcatc tggattcttt atggtgaagt ctccagacat tggataactg
    48901 ctggtctaat gcgcctttga gtatggggtg attgatttta ataccgggga ggtacggctt
    48961 tttgaggaaa atattctggg atttacattt ggcgattatt acatttcctg taactgcaag
    49021 gacacggatg atgaagatat gaggaatata gacttgctga ttttctactg tcttgaacgg
    49081 tattaggact gaatctgctg cgcggagtgc ggcaagagcg accggaggga gtacacacag
    49141 gccctgcctg tgtgaaaagc cataccgcaa ggtgcattcg caaaaaagag gccgcgcatt
    49201 ttgctgaggc ttggggtgtc cccaacaagc aaaacgagaa cgccgcaggc gggcaagtgg
    49261 tggatcagaa tatccgtaaa ggatattctg atccattgct tgccagtatt atcgggatgt
    49321 tttgacaacc gctgtaatcg aaacatccca aacattaaga aggtgttaat tattattatc
    49381 ttgatttaat tcgtttaaac caataatata gatacataca ccatgaaaag aagcgagtat
    49441 cccaatgacg gatgattaaa atccgaaaag aaatcgcttt gaaactacag ggaaactaca
    49501 gactgttatg ttatcttctt aaaatggagg gatttttatg tcgatacgaa ttctacttgt
    49561 cgaggatgat gatcatatct gtaatacagt aagggcgttt ctggctgagg caggatatca
    49621 ggtggatgcc tgcacagatg gaaatgaggc atacaccaag ttttacgaaa acacttatca
    49681 actggttatt cttgatatta tgctgcccgg tatgaacggg catgaacttt tgcgtgaatt
    49741 tcgtgcgaaa aatgatactc ccattctgat gatgacagcc ctgtcggatg acgaaaacca
    49801 aatccgggcg tttgatgcag aggcagacga ctatgtaaca aagccattca agatgcagat
    49861 tttactaaag cgggtggaag ccctgctgcg gcgcagcggt gcgctggcaa aggaaatccg
    49921 tgtcggcagg ctgacacttc tgccggagga tttcacggta ctttgtgacg gtacagagct
    49981 gcccctgaca cgaaaagaat ttgaaatcct tttgctgctg gtgcagaaca aaggcagaac
    50041 cttaacgcat gaaatcattt tgtcacgtat atggggatat gactttgagg gtgatggcag
    50101 cacagtccac actcatatca aaaatttgcg ggccaagctg ccggaaaata tcatcaaaac
    50161 cattcgcggt gtaggatacc gattggagga atcataataa tggaaagaaa agggattttc
    50221 attaaggttt tttcctatac gatcattgtc ctgctactgc ttgtcggtgt aacagcaaca
    50281 ctgtttgcac agcaatttgt gtcttatttc agagtgatgg aattacagca aacagtaaaa
    50341 tcctatcagc cattggtgga actgattcag aatagcgata ggcttgatat tcaagaggtg
    50401 gcagggctgt ttcactacaa taaccaatcc tttgagtttt atattgaaga taaagaggga
    50461 agcgtactct atgccacacc aaatgccaat acatcaaata gttttagacc caactttctt
    50521 tatgtggtac atagagatga taatatttcg attgttgctc aaagcaaggc aggtgtggga
    50581 ttgctttatc aagggctgac aattcgggga attgttatga ttgcgataat ggttgtattc
    50641 agccttttat gcgcgtatat ctttgcgcgg caaatgacaa cgccgatcaa agccttagcg
    50701 gacagtgcga ataaaatggc aaacctgaaa gatgtaccgc cgccgctgga gcgaaaggat
    50761 gagcttggcg cactggctca tgatatgcat tccatgtatg tcaggctgaa agaaaccatc
    50821 gcaaggctgg aggatgaaat cgcaagggaa catgagttgg aggaaacaca gcgatatttc
    50881 tttgcggcag cttctcatga gctaaaaacg cccatcgcgg ctacaagcgt tctgttggag
    50941 ggaatgcttg aaaatatcgg tgactacaaa gatcattcta agtatctgcg cgaatgcatc
    51001 aaaatgatgg ataggcaggg caaaatcatt tccgaaatac tggagcttgt cagcctgaat
    51061 gatgggagaa tcgtacccat agctgaaccg ttggacatag ggcgcacggt tgccgagttg
    51121 ctgcccgatt ttcaaacctt ggcagaggca aacaaccagc ggttcgtcac agatattcca
    51181 gccgggcaaa ttgtcctgtc cgatccgagg ctgctccaaa aggcactatc caatgtcata
    51241 ttgaatgcag ttcagaacac gccgcaggga ggcgaggtac ggatatggag tgagcctggt
    51301 gctgaaaaat gccgcctttt tgttttgaac atgggcgttc acattgatga tactgcgctt
    51361 ccaaggctgt tcaccccatt ctatcgcatt gatcaggcgc gaagcagaaa aagtgggcga
    51421 agcagaaaaa gtgggcgaag cggtttagga cttgccatcg tacaaaaaac gctggatgcc
    51481 atgagcctcc agtatgcgct ggaaaacacc tcggatggcg ttttgttctg gctggattta
    51541 ccgctcacat caacattgta aatatttaaa acttaaatga ttttgggctc tttgtcaaat
    51601 aggactgata gagtgagata agaacatcta aggtagaatt ccttttctac tttagatgtt
    51661 ttttgattca taggtaatca gattatttag taagaaaatt ctggtcttca ttttccgaaa
    51721 gcttcgaaag ccataagcga ctcgtttcaa tgctttgatg tgggtatgca gattttctat
    51781 tttggcattt gaataaggca attcgagggc taaacgaatg ccggattcat agtttataaa
    51841 agcttttttt atagaatgca gttcttttgg aacggaattg ggcatcgttc ttacaagttt
    51901 aaagaaagtg tccgcctctt tgtcgtgaaa cgcttgaaga atttcttgat agtaaaaata
    51961 ggcgattcgt aattcgtcag agatcgaaag cagacgatcc accacttcac tttcggtgag
    52021 atacgcccaa ccaaaattgc gccatttggt ccatttgtca taaacaagct tgtcctgtcg
    52081 tttgatcaga agccgagaca acgcctttaa ttgtcgataa tatttggctt gtgttggatc
    52141 gtttcgatca aagcttttca tgattcgtac gcgaatatcc tcaaatttac gaatgagatg
    52201 tttgacaatg tgaaaacgat ccacaacgag ttttgccttt ggaaaacatt cctttatcag
    52261 agaggcataa gaaacattca tgtccgtcac gatgaccttt accttcaatc gtgcgcgtcg
    52321 ttcaaattgc ataaaataag aaacgagagc ctttttcttc cgtgaaggaa gaatatccag
    52381 taattttcca gtatcgccat ccatacaaga aaaggagtag ggaccgactt gatttttcag
    52441 tgaacgaaat tcatccatta ataaacaacg cggtaaccaa tttcttttta cttttgtcat
    52501 ggggatcaga gaagcgagtg tccgagaaac ggtcgaccaa gaaacgccgc aatgcttagc
    52561 aattgtcgtc attgcttgtt tttcagttag ctcttctaaa attttatagc gcacttgttt
    52621 agcgataaag cagtttctat cgacaatgta ggtattcgcc gtaaaatagg tgtggcagcc
    52681 acgacagtgg tagcgttgtt tcgctaaagc aagataagtc agttggttcg cacatttatt
    52741 aagttgaatg agcgattttt tctttccgtt cttaacgatc atgccttcat gattcatctg
    52801 tttacacaaa ggacagcgac gaatttcttt acttaacgtc gcagaaacaa caagactctt
    52861 gatattctta atgctcttcg attccacatt tgtgatgaaa atgtttttat ctttgattcc
    52921 aagtagtagt ttgatatgat gaagatcagg catacagaac gctcctttga ttgtgttgtg
    52981 gtgattcaat tctaacggag cttctgtatg ttttgttttt tcatgctcaa aagggaccga
    53041 tagaatgatt ttctatc
//
LOCUS       DAFLWC010000008        52637 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.008, whole genome shotgun sequence.
ACCESSION   DAFLWC010000008 DAFLWC010000000
VERSION     DAFLWC010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 52637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52637
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.008"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            84..938
                     /locus_tag="L1V17_000449"
     CDS             84..938
                     /locus_tag="L1V17_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HBN1235240.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            939..2276
                     /locus_tag="L1V17_000450"
     CDS             939..2276
                     /locus_tag="L1V17_000450"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBN1235241.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            2281..2505
                     /locus_tag="L1V17_000451"
     CDS             2281..2505
                     /locus_tag="L1V17_000451"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBN1235242.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            2507..3397
                     /locus_tag="L1V17_000452"
     CDS             2507..3397
                     /locus_tag="L1V17_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBN1235243.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            3406..4224
                     /locus_tag="L1V17_000453"
     CDS             3406..4224
                     /locus_tag="L1V17_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HBN1235244.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            4331..4780
                     /locus_tag="L1V17_000454"
     CDS             4331..4780
                     /locus_tag="L1V17_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBN1235245.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            4798..6480
                     /gene="recN"
                     /locus_tag="L1V17_000455"
     CDS             4798..6480
                     /gene="recN"
                     /locus_tag="L1V17_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBN1235246.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(6535..6651)
                     /locus_tag="L1V17_000456"
     CDS             complement(6535..6651)
                     /locus_tag="L1V17_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HBN1235247.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(6724..7680)
                     /locus_tag="L1V17_000457"
     CDS             complement(6724..7680)
                     /locus_tag="L1V17_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBN1235248.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            7851..8219
                     /locus_tag="L1V17_000458"
     CDS             7851..8219
                     /locus_tag="L1V17_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HBN1235249.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            8389..8820
                     /gene="mraZ"
                     /locus_tag="L1V17_000459"
     CDS             8389..8820
                     /gene="mraZ"
                     /locus_tag="L1V17_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HBN1235250.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            8841..9800
                     /gene="rsmH"
                     /locus_tag="L1V17_000460"
     CDS             8841..9800
                     /gene="rsmH"
                     /locus_tag="L1V17_000460"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBN1235251.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            9805..10206
                     /gene="ftsL"
                     /locus_tag="L1V17_000461"
     CDS             9805..10206
                     /gene="ftsL"
                     /locus_tag="L1V17_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HBN1235252.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            10207..12399
                     /locus_tag="L1V17_000462"
     CDS             10207..12399
                     /locus_tag="L1V17_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBN1235253.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            12425..13387
                     /locus_tag="L1V17_000463"
     CDS             12425..13387
                     /locus_tag="L1V17_000463"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBN1235254.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            13401..14762
                     /locus_tag="L1V17_000464"
     CDS             13401..14762
                     /locus_tag="L1V17_000464"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBN1235255.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            14788..15876
                     /gene="murG"
                     /locus_tag="L1V17_000465"
     CDS             14788..15876
                     /gene="murG"
                     /locus_tag="L1V17_000465"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBN1235256.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            15891..17111
                     /locus_tag="L1V17_000466"
     CDS             15891..17111
                     /locus_tag="L1V17_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HBN1235257.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            17267..18592
                     /gene="ftsA"
                     /locus_tag="L1V17_000467"
     CDS             17267..18592
                     /gene="ftsA"
                     /locus_tag="L1V17_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HBN1235258.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            18615..19856
                     /gene="ftsZ"
                     /locus_tag="L1V17_000468"
     CDS             18615..19856
                     /gene="ftsZ"
                     /locus_tag="L1V17_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBN1235259.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            19873..20550
                     /locus_tag="L1V17_000469"
     CDS             19873..20550
                     /locus_tag="L1V17_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBN1235260.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            20564..21163
                     /locus_tag="L1V17_000470"
     CDS             20564..21163
                     /locus_tag="L1V17_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBN1235261.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            21178..21465
                     /locus_tag="L1V17_000471"
     CDS             21178..21465
                     /locus_tag="L1V17_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBN1235262.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            21514..22296
                     /locus_tag="L1V17_000472"
     CDS             21514..22296
                     /locus_tag="L1V17_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBN1235263.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            22317..23024
                     /locus_tag="L1V17_000473"
     CDS             22317..23024
                     /locus_tag="L1V17_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBN1235264.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            23286..26084
                     /gene="ileS"
                     /locus_tag="L1V17_000474"
     CDS             23286..26084
                     /gene="ileS"
                     /locus_tag="L1V17_000474"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBN1235265.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(26133..27659)
                     /locus_tag="L1V17_000475"
     CDS             complement(26133..27659)
                     /locus_tag="L1V17_000475"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HBN1235266.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(27674..28321)
                     /locus_tag="L1V17_000476"
     CDS             complement(27674..28321)
                     /locus_tag="L1V17_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HBN1235267.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(28505..28834)
                     /locus_tag="L1V17_000477"
     CDS             complement(28505..28834)
                     /locus_tag="L1V17_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HBN1235268.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            29011..29739
                     /gene="sfsA"
                     /locus_tag="L1V17_000478"
     CDS             29011..29739
                     /gene="sfsA"
                     /locus_tag="L1V17_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HBN1235269.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            29755..30768
                     /locus_tag="L1V17_000479"
     CDS             29755..30768
                     /locus_tag="L1V17_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1235270.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            30768..32045
                     /locus_tag="L1V17_000480"
     CDS             30768..32045
                     /locus_tag="L1V17_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBN1235271.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            32108..34810
                     /locus_tag="L1V17_000481"
     CDS             32108..34810
                     /locus_tag="L1V17_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBN1235272.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            34962..35279
                     /locus_tag="L1V17_000482"
     CDS             34962..35279
                     /locus_tag="L1V17_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1235273.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            35309..35629
                     /locus_tag="L1V17_000483"
     CDS             35309..35629
                     /locus_tag="L1V17_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBN1235274.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            35737..37197
                     /locus_tag="L1V17_000484"
     CDS             35737..37197
                     /locus_tag="L1V17_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1235275.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            37265..37486
                     /locus_tag="L1V17_000485"
     CDS             37265..37486
                     /locus_tag="L1V17_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235276.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            37517..37699
                     /locus_tag="L1V17_000486"
     CDS             37517..37699
                     /locus_tag="L1V17_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HBN1235277.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            37699..38112
                     /locus_tag="L1V17_000487"
     CDS             37699..38112
                     /locus_tag="L1V17_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBN1235278.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            38235..39416
                     /locus_tag="L1V17_000488"
     CDS             38235..39416
                     /locus_tag="L1V17_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1235279.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(39487..39651)
                     /locus_tag="L1V17_000489"
     CDS             complement(39487..39651)
                     /locus_tag="L1V17_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235280.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            39805..39878
                     /locus_tag="L1V17_000490"
     tRNA            39805..39878
                     /locus_tag="L1V17_000490"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:39839..39841,aa:Arg,seq:cct)
     gene            complement(39947..41086)
                     /locus_tag="L1V17_000491"
     CDS             complement(39947..41086)
                     /locus_tag="L1V17_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1235281.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(41385..42020)
                     /locus_tag="L1V17_000492"
     CDS             complement(41385..42020)
                     /locus_tag="L1V17_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235282.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(42133..42768)
                     /locus_tag="L1V17_000493"
     CDS             complement(42133..42768)
                     /locus_tag="L1V17_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HBN1235283.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(42802..43263)
                     /locus_tag="L1V17_000494"
     CDS             complement(42802..43263)
                     /locus_tag="L1V17_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBN1235284.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(43393..43824)
                     /locus_tag="L1V17_000495"
     CDS             complement(43393..43824)
                     /locus_tag="L1V17_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBN1235285.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(43842..44162)
                     /locus_tag="L1V17_000496"
     CDS             complement(43842..44162)
                     /locus_tag="L1V17_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1235286.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            44461..45237
                     /locus_tag="L1V17_000497"
     CDS             44461..45237
                     /locus_tag="L1V17_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HBN1235287.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            45252..45455
                     /locus_tag="L1V17_000498"
     CDS             45252..45455
                     /locus_tag="L1V17_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1235288.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            45471..45809
                     /locus_tag="L1V17_000499"
     CDS             45471..45809
                     /locus_tag="L1V17_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HBN1235289.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            45796..45975
                     /locus_tag="L1V17_000500"
     CDS             45796..45975
                     /locus_tag="L1V17_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235290.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(46018..46488)
                     /locus_tag="L1V17_000501"
     CDS             complement(46018..46488)
                     /locus_tag="L1V17_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235291.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            46575..47273
                     /locus_tag="L1V17_000502"
     CDS             46575..47273
                     /locus_tag="L1V17_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HBN1235292.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            47451..47792
                     /locus_tag="L1V17_000503"
     CDS             47451..47792
                     /locus_tag="L1V17_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235293.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            47785..48456
                     /locus_tag="L1V17_000504"
     CDS             47785..48456
                     /locus_tag="L1V17_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HBN1235294.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            48462..49154
                     /locus_tag="L1V17_000505"
     CDS             48462..49154
                     /locus_tag="L1V17_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235295.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGGEK"
     gene            49151..49900
                     /locus_tag="L1V17_000506"
     CDS             49151..49900
                     /locus_tag="L1V17_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1235296.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            49912..50181
                     /locus_tag="L1V17_000507"
     CDS             49912..50181
                     /locus_tag="L1V17_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235297.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
     gene            50187..50351
                     /locus_tag="L1V17_000508"
     CDS             50187..50351
                     /locus_tag="L1V17_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235298.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            50344..50643
                     /locus_tag="L1V17_000509"
     CDS             50344..50643
                     /locus_tag="L1V17_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235299.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            50643..50945
                     /locus_tag="L1V17_000510"
     CDS             50643..50945
                     /locus_tag="L1V17_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBN1235300.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            50985..51350
                     /locus_tag="L1V17_000511"
     CDS             50985..51350
                     /locus_tag="L1V17_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235301.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            51840..51980
                     /locus_tag="L1V17_000512"
     CDS             51840..51980
                     /locus_tag="L1V17_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235302.1"
                     /translation="MNEIAADHELSETALIDQIELARQYFVPYADTWSKHKNDIIFPE
                     EQ"
     gene            51977..52159
                     /locus_tag="L1V17_000513"
     CDS             51977..52159
                     /locus_tag="L1V17_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235303.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKI"
     gene            52172..52366
                     /locus_tag="L1V17_000514"
     CDS             52172..52366
                     /locus_tag="L1V17_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235304.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
     gene            complement(52399..52611)
                     /locus_tag="L1V17_000515"
     CDS             complement(52399..52611)
                     /locus_tag="L1V17_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235305.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
BASE COUNT        17739 a         8808 c        10912 g        15178 t
ORIGIN      
        1 tctatgaatc atcataaacc tgttataaat cgggaaaatt ctatggtaga atgaaaacac
       61 aaaaaatatc tgggagtggt tagatggcag aattgattaa cggaaaagaa ttagctgaaa
      121 aaatgcaggc agagattgct gaaaaaatcc aaaaattgaa agataatggt atccatcccg
      181 gattagtcgt tttattggta ggggaaaatc cagccagcca aatctatgta agaaataaag
      241 aacgtgtagc aaaagaaatc ggaatccatt cattggtaga gcgttatcct gagacgattt
      301 ctgaagacga actacttgca gaaattgaaa aatacaatca agatcctagt tttcatggta
      361 tattggtcca attaccattg ccaaagcata tagatgaaga aaagatcctg ttagctatcc
      421 gccctgaaaa agacgtagac ggttttcatc cgatgaattt aggcagactc cttgcgggta
      481 aaccggacaa gattccttgt actccatacg gcatcatgaa aatgtttgaa gcttattcta
      541 tcgatccggc gggtaaacga gcagtagtta tcggacgaag caatatcgtc ggtaaaccga
      601 tggctcagct actcttgatg gcagatgcaa ctgttactgt tgctcattct aaaaccgaaa
      661 atctggctga actggcacaa gaagcagata ttttagtcgt agcaatagga cgtggacatt
      721 ttgtcacaaa agaattcgta aaaccaggtg ctgtagtgat agatgtaggg atgaatcgtg
      781 atgctaacgg taagctgatc ggtgatgtga aatttgatga agtggagcct attgcaggct
      841 ggatcactcc tgtgccaaag ggtgtagggc caatgactat cacgatgctg atgtatcaaa
      901 ccgtaaaatc tgccgaagct tttggagcag gtgaatagat ggcacaagaa tatttaactg
      961 tcactacatt aacgaagtat ttgaaaagaa aatttgatgc cgatccttat ttagaacgcg
     1021 tatatttaac aggcgaaata tcgaatttcc gtttacgtgc caatgcccat caatatttca
     1081 gcttaaaaga tgaccatgca aaaatatctg ctattatgtt caaaggagca ttccaaaaat
     1141 tacgattcca gccaaaagaa ggaatgaaag tccttgtcgt tgggcgtatt tcattatatg
     1201 aagcgggagg ttcttatcaa atctatgtag agcacatgga gcctgatgga ataggtgctt
     1261 tatatcaaga attggaagaa cgaaaagaaa agctgatgaa ggaaggcctt tttcaagggc
     1321 ctaaaaaaat gctgccacgt ttcccaaagc gaatcgcggt ccttaccagt ccaagcggag
     1381 cggttatccg cgatatcatc acgacggtga aaagaagata tccaattgtc caattggttt
     1441 tgttcccaac agttgtacaa ggaaaccaag cagcggacaa tgttgtcagg aatatccaga
     1501 gagtagaaga gatgggcaat ttcgatacaa tgatcatcgg tcgtgggggt ggttcgattg
     1561 aggatttatg gccgtttaat gaagagcggg ttgctcgggc gatttatcaa gctaatacgc
     1621 cggtgatttc atctgtagga catgaaacag ataccacgat cgctgattta gtagcagatg
     1681 ttcgggctgc cactccaaca gcagctgcag aattagctgt tcctgttttg tcagaagagt
     1741 tgatgcgcat tcaagaacgg caagctagat tgcagcaggc gtttgtacgc cagatccagc
     1801 gcaaacaaga acggttcgag cgtgctcgac gttcctatgt atttcggcag cctgaaagat
     1861 tgtatgaagg tcagaccatc aaattagacc agttgaaaca gcgattatat caagctacac
     1921 agcaaattta tcatgcgaaa gaaaaacaaa cgatcgcatt aagccaccaa ttggaacaag
     1981 tggctccgct ttatcgagtt aaagcagctc gccaagaaac tgcttatcta gaaaaacgct
     2041 tagaagagaa aatccaacaa tatatgaaac aacagcagca gcgttttgct caagctgttc
     2101 aatctcttga tttgttgagt ccattgaaaa tcatgggaag aggctacagc tatacgacgt
     2161 taaatgatca agtagtaaaa agtgtcaccg agattcatca aggggatttg ctgacgatcc
     2221 attatcaaga tggaatcgtt aaaggacaag tacaagagat agacaaagga gaataaaaat
     2281 atggaaaatc caacttttga agagtcactg caagaattag aaaaaattgt catgcagtta
     2341 gaacaaggag acgttccatt agaatcagct ctagattcgt ttaaacgagg aatggaatta
     2401 agcaaacatt gccaagatac attagctaaa gcagaagaga ccttgacgaa aatgatgaca
     2461 gaatcaaatg aagaagttga ttttgacgga aacgaggaaa gctgagatga gattaactga
     2521 cttttcagct attcatctac ctgctgtaga aaaagaaatc ttgtcttttt tagatgagca
     2581 tacaacggat agaggactct atgatgcgat gagttattca gtgaaagcag gcgggaaaag
     2641 aatacgtccc ttattacttt taacggccgt tgcttccttt gatgagccta ttgatgttcc
     2701 cgtctatcaa gtagcagctg ctttagaaat ggtgcatacg tattccttga tccacgatga
     2761 tttgcctgcg atggacaatg atgatcttcg tagaggaaaa cctaccaatc ataaagtatt
     2821 cggcgaagca ttagctatat tggccggaga tggtttgctt acaggagcat tccagctaat
     2881 cagtatggca cacttaggta attctcctaa gcttctgctg cttcagcaat tagctgtttg
     2941 tgcgggatca caaggtatgg ttgctgggca agctgcagat atcgagggcg aatcgaaaaa
     3001 gctttcttta gaagaattag catttattca tgaaagaaag acagggcatt tgattcgtta
     3061 tgccttgctg gctggtggca tattagcgaa gcaacctgaa gaaatcttat tgctacttca
     3121 acgattagcc gaacatttag gtttagcttt tcagataaga gatgatctac tcgatgtgat
     3181 tggtacaacg aaaacattag ggaaaacagc tggtaaagat gaacgtatgg aaaaaaatac
     3241 ttacccgcgt ttattaggcc tagaaaagac acgtgaggcg ttggagattg agctgttatc
     3301 cgccaacaag atcatagaca aattagaaga ggacgttttt tcttttgatg gcgggctgat
     3361 gcgccagatg atcaagcaat ttgatgtgga gaaatgaggg aaagaatgga aaaagaacgc
     3421 gtagatgtat tagcggtcaa acaaggatta tttgaaacaa gagaacaagc caaacgttca
     3481 gtgatggctg gtttgattta caacgaaaaa aacgagcggt ttgataaacc gggagaaaaa
     3541 attccagtga gtagtgaatt aagagtcaaa ggtaaaaaac ttccttatgt ttctcgaggg
     3601 ggattaaaat tagaaaaagc actcaaagca tttgatctat ctgttgaagg aaaaacattg
     3661 ttagatattg gtgcatccac tggcggattt actgatgcag ctttgcaaaa tggcgcaaaa
     3721 atgagttatg ctttagacgt tggctacaat cagctagctt ggaaaataag acaagatcct
     3781 agagtcgtcg taatggaaag agtgaatttt cgttatgcaa aacccgaaga ctttacctta
     3841 ggaattccag aagttgctgt tatcgatgtt tcttttattt cactaaaact gatgctgcct
     3901 ccattacatg ctattttaaa agaagaggga gaagtgattg ctttaatcaa accccaattc
     3961 gaagcaggca gagaagctgt agggaaaaac ggaattgttc gtgaccctca gacccatcaa
     4021 aaagttttag aagacatttt gtcatttgcg gcacaaggtg gatatgatgt gctggaatta
     4081 agttattctc cgatcacggg gggagaagga aatatcgagt tcttggctca cttgaggaaa
     4141 gtacccgaaa gcggaacaat caattcagct attaatatgg cagaagtggt ttcaaatgca
     4201 cacgaacagt ttgaccataa ataaattgta actgtgaaaa tcaagtgaga agtatgcgga
     4261 ttcttcttta ttataccaag gaaataagct atcattgatt aagaagaata tgctaaggag
     4321 cgaagacgta atgagaaaaa aagatcggca tcgtttgatt actcgattgt tgagtgagca
     4381 agatatccga aagcaggaag aatttgttga aatcctgaaa agcaaaggaa tatctgttac
     4441 tcaagctacg atttccagag atataaagga actgaaactg atcaaggtac cggcttcaga
     4501 tggcggctac cgttatagca taccagctga aacaaacgaa gatgtaaata ctaaattgga
     4561 aaaactatta aaagacgctt tcgtggcagt tgaccaaatg gaaaaatttg ttattttgaa
     4621 aacattgccg ggaaatgctt cggcagcagc aaatttgatt gataaacgtt acaagaaaga
     4681 attattttcg attatcaatg atgacgataa tgttttgatg attacacgaa ctgaagacca
     4741 ggcagtttta ttgaagaaag acttcctgca ttacctttaa gttgaggagc gaatgtgatg
     4801 ctacaagaaa tcagtattac taactttgcg attattccgg aattgcggct ttcttttcac
     4861 gaaggaatga ccgcgctgac cggagagact ggtgcgggta aatccattat tatcgatgct
     4921 ttaggtctgt tagcaggagg aagaggttca agcgattata tacgtcaagg agcagaaaaa
     4981 tgtgtgcttg aagggttgtt tgaactacca aaacaagaag gattctctga actgatggtt
     5041 gaattaggga tcgaaacaga tgaggacaat ctgattgttc gacgggatat gtccttaact
     5101 ggaaaaaatg tttgtcgagt gaatggtcat attatcacat tagctaatct gagaagaatc
     5161 ggcagttatt tagtagatat ccaaggacaa aacgaacatc aggaactgct ccagcctgaa
     5221 tcacatcttg ctttattgga tcgttttgga gatgtagctt tccaacagaa gaaaaagagt
     5281 tatcagcaag aatatatctc ttatcgtgag ctggaaaaaa gggtacgaaa agtgcagcaa
     5341 aatgaaaaat cctatgttca gagaatagat atgctccatt tccagcaaga agaaatagct
     5401 gctgctgatt tgcaagtcgg agaagaagag aaattaaaag aagaaagaga aaaacttagc
     5461 aattatcaaa aaattgctga tggattagct gcaggttacg gagcactgac gaataatgaa
     5521 caaaacagtg tagatggtgt tggcttggcc gtttcagaac tgcaagggat cgcccatcta
     5581 gatgtggagt atgaagcaat ttatgaaaat atccaaagtg cttactattt gctgcaagat
     5641 gcaatcggcg atatgagtcg tcagattgat ttattggagt tagatgagag tcgtttagaa
     5701 gaagttacgc aacgtttaga attaatccga cagttgaaac gtaaatacgg cgaatccatt
     5761 gagtcaatat tggcttacta tgacgaaatc accgaagagc tagcttcttc tgatttttca
     5821 gaaggtcaat tggacaaaat gaaagaggaa ctagagcaaa aagagcttct acttcagcaa
     5881 caagccgcag atcttcatga agcgcgtaaa aaaatcgcaa aagaattgga aaaatccatt
     5941 ctgcatgaat tgaaaagtct gtatatggaa aacactgagt ttgaggtacg tttcttaaaa
     6001 gaagaaaata gacaattgaa tcatgatgga tttgaccaaa tcgaatttta cattacgacc
     6061 aatccaggag agccactgaa gcctttggtg aaagtcgctt ctggtggcga actgtctcgg
     6121 atgttgcttg ctttgaaaac tattttttct tctgagcaag gtgtgacaag tattattttt
     6181 gatgaagtgg atacaggtgt gagcggaaga gttgcacagg ccatcgcaga taaaatttct
     6241 caaatatcga aatactctca agttttgtgc atcactcatc tgcctcaagt tgctgcagtc
     6301 gccgactatc aatattatat tgtgaaagca gtgattgatg gacgtacgca aacttctgtt
     6361 tcagagttga aaacaaaaga aagagaagaa gaaattgcac gtatgctggc tggaagtgag
     6421 attacaaaac tcacactcga acatgcaaaa gaactattga aactcgcaaa aaggacctga
     6481 gccacctcgc agtggttcag gtccttttca gcagctgata gctatatttt atttttacat
     6541 gacactcatt acagcagtca atacaacaga tccaatcgtt aaaatcagca ttgtccaaat
     6601 gacaaatttt gttactttag caaaagtact tgtttgtttt ttttcacgca ttgttttcaa
     6661 cctcgtcatt aattagttga ttcaagtgta caatcttttt tccatttcca caagagggct
     6721 tttttataaa aacttccctt tttttaaata ataggtagtt acgatacaaa taaataatgt
     6781 taatagaact agccatataa aggcatcatc cctttcagca ataggtaact taatgttcat
     6841 tccatagata ctgccgacga ttgtcggtat agttaaaata atcgttaaag aagttaaaat
     6901 tttcataata ttattcagat tattcgatac gattgctgaa aaagtctgat tcatttgttc
     6961 tactagtttt aattgaatgc gagaagtagt cattgcctgc tctgtttcca ccaatacatc
     7021 acgtaaatga tttttcaaag catgattttc ttggaaaagt ttattttgcg ctagttcttt
     7081 caatgcatct aaattagcag aagtcgcttc tctgaaataa acgaggcttt tttggatatc
     7141 catgatttga taaagttgtt tgttttcagt ggatacttga agtttggctt ccaaagtatc
     7201 gcattgagat tgaagcgtag ctaaataact gttgtaagag agtgtgacct gccaaatgaa
     7261 ttgaaagaag atattgagat taggcgaaat atcacttttt ggaaaggtct ggctaaagac
     7321 tttctttaaa aacagtggtt catgattcgt aattgtgata agcttctttt tgggcgtcaa
     7381 aataatagag agcgggtatg tatccacttg aaaataaccg ctaggacttg ttttagcaaa
     7441 aggatattgt aacaataata acgctggctt tgtcaacttt gattgattga attcttctgt
     7501 acgggaattt tctgcatcgt ccaatatgga agtgatgtaa tctgacggaa tttcaaattg
     7561 atgtgtcagc tgatgaatct cttcttgatt aggacgttct acacaatacc agatcgtttg
     7621 gtcagtttcc tttccggtat tacgcagttt ctcattatct aatgtaaaat atttgatcat
     7681 gattttcctc ctgttgcctg tttcttttat tataacggat agggaattgg aatacatgga
     7741 atgtgtttgt aagatataga atataactgc ataaatttaa ataaaatgaa acagttgtgt
     7801 aaagtatata cagtatactt gaagcaacga taaaaaagga gtttacgttc atgggcacat
     7861 tcacaccact tatcttgttt tggtatattt acccggtaat cgttttgttt ggttgccaat
     7921 ttcttgtaaa attattttcg ttaaatcgtc gttttaaaat aaaagcccct gatttggcga
     7981 ttcctttttt gtggggcggt atgcatgcat tgtctagaaa tacagggaca atttctatct
     8041 taccgttttt ctttatttct gttttgctaa tgggaatttg tattgctgtt ttccaagcat
     8101 attattatga agaaattatt tatccgcgtt atttcaagat gacttggcgt ttggtttttc
     8161 tgttgacaat cgtcttgtac gctgtcttga tcattgtgaa catactttct tacctatgaa
     8221 aaaaatagaa aagctgtaaa aagtctttta aaaggctttt tgcagcttga tttttaaaaa
     8281 aatgtttatg aataaaaaaa gttgttcccg gatttcccag aaaaggtggt agaaagtggg
     8341 ggattgtggt agactaattt tagttagtgg aggaatgggg ggctttcaat gttgatgggt
     8401 gaattccaac ataatattga tgcaaaagga cgtttaatcg tgccctcaaa acttcgtgaa
     8461 gaacttggcg aaaagtttgt tctgacacgc ggattggatg gctgtctttt cggctatccg
     8521 atgagcgaat gggaaaatct ggaagctaaa ctgaacgaaa tgccgttggc taaaaaagac
     8581 gcacgtactt ttgtgcgatt cttctattcg gctgccactg aatgcgaact tgataaacaa
     8641 ggacgaatca atatacccag cacgttaaga aattatgcag ctttgacaaa aggttgcgta
     8701 gtcatcggtg tatctaaccg aattgaaatt tgggatgaga cacgatggca agatttttct
     8761 gcagcagcag aagagaactt tgacgaaatt gctgaaagta tgattgattt cggactataa
     8821 gaataggaag aggctgacta atgactgaaa catttcaaca ctatacagtc atgttgaaag
     8881 aaacggtaga tggattgaac atcaaaccgg atggcgttta tgtagactgt acactcggcg
     8941 gtgccggaca tagtgaatat ttattaagcc aactaagttc taaagggcat ctgtatgcgt
     9001 ttgaccaaga tcaaaaagca atcgatcacg ccaagctgcg tttagcttct tatgtcgaac
     9061 aaggtatggt cacatttatc aaagcgaact tcagagaatt agaagaacgc ttgagtgagc
     9121 atgtagataa ggtagacggc attttgtatg atctaggggt ttcctctcct cagctagatg
     9181 aagcagaacg tggatttagt tatcatcaag atgcaccgtt ggatatgcgc atggatcagt
     9241 cagctccttt atccgcttat cacgtaatta atgaatattc ctaccatgaa ttagtaaaga
     9301 ttttcttccg ctatggcgag gagaaatttt ccaaacaaat tgctcgtgaa atcgaacgag
     9361 tacgaaaaac aaaaccaatc caaacaactg gtgagcttgt cgaaatcatt aaacaagtca
     9421 tcccagctcc cgcaagaaga aaaggcgggc atcctgcaaa aagaattttt caagctgtgc
     9481 ggattgcagt aaatgacgaa ctcggtgccg aagaggcctc tttagaacag gcaatccggt
     9541 tattgaaagt caatggaaga atcagcgtaa tcacattcca ttcattggaa gacagaattg
     9601 tcaaaagtat gtttaaagaa tatagtacgg tacaagatct accaccggga cttcctgtca
     9661 tacctgacga attccaacca gaactgaaag tcattactcg taaaccaatc cttccttcag
     9721 aggaagagct aacagaaaac aatcgatcac gcagtgcaaa gttacgtatt gcagaaaaaa
     9781 taagaatgaa agaggagtag aatgatggca gaattaaaga aaatgcaaga ttacgaatat
     9841 gatttacctg aattggtgga tcagccggaa caacaaatgc ctgattcttc ttcgaatcaa
     9901 gaaatcattc ttccacaatc accggcaaaa cgattaaagc agatttctgc tttggaaaaa
     9961 attgctgtgg caagcgtggc gattgctatt gttgctttat gtgttttaac agttatgctg
    10021 cgcacaaata tcagcggagc tgaaaaagaa atcacgtcaa tacaaacaga aatcaatgat
    10081 aaaaagcaag aaaaaacgag tttagaacaa gaaaaaaacg aactttctcg tactgaacgg
    10141 attaaacaaa tcgcagaaga aaaaggattg tctattaatg acgacaattt aaggaaagtg
    10201 aagtaaatga gtcttaaaaa taaaattcgg cggtttatgg aaaagaaaaa tctaaatccg
    10261 atgaacaatc gcaaaaaagt aggtatcatt ttatttgcta cgagtattgg attgttcttt
    10321 ttatttgccg tccgtttctc gtatatcgtt attggaggtc atgttgctgg tacctcatta
    10381 gctgaaaaaa caaaacagtt gtaccaagga agtgaagtag taaaagcaaa aagaggaacg
    10441 atttatgatc gtaacggtgt ggcgctcgca gaagatgcct cctcttattc aattaaagcg
    10501 atactctcaa aaacatatac ctctggggat aaaaaactgt atgttgaaga aaagaatttt
    10561 gataaaatag cagaaatcct gcataagaat ctttctatag acaaaaaaga tgcactgaat
    10621 attttagagg acggcgcaaa aaaagagctg tatcaagttg aatttggtag ctatgggaaa
    10681 aatatctccc aagaaaccaa gcaaaacatc gaagcggaca tgaaaaaaga aggtgtcgct
    10741 ggtctttatt ttgtcgacca tcaggctcgg atgtatccaa atggcgtctt ttcttctcat
    10801 tttattggat acgcagttcc agacaaagat gagaatggct tagttggtaa actaggtttg
    10861 gagtctgctt acaatgatat cttgagcggt aaagatggta agattattta tcaaaaagat
    10921 aattttcaaa atcctctgcc aggtacagtg gcagaagaag aaaaagctgt cgacggacaa
    10981 gatatctaca cgactttaga cagcagacta caaagttatt tagaaacact gatggatcaa
    11041 gtaaatgaag aatatcagcc agaagaattg acagcagtcc tgatgaaagc aaaaaccgga
    11101 gaaatcttgg caatgggaca acgacctact ttcaatcctg aaacaatgga aggattgact
    11161 ggaaaagatg ctatctggcg taatttcttg gtacaagata gttatgaacc aggatcaacc
    11221 atgaaagttt tcactactgc agctgctatc gaagaaggag aattcaacga gaatgaaacc
    11281 ttccaatctg gaaaaatcca agtagaagat gctacgatca atgaccatga ctttggtgaa
    11341 aaaggtgtgc tgaccatgcg tcaagctctt tcatggtcaa gtaacgtcgg gatggtcata
    11401 ctggaacagc gattaggcgg acgatggtat aactatttac aaaaactggg atttggacaa
    11461 agtactcatt ctggattaga tgatgaagta aacggtgctt tacctacatt aaatattgtc
    11521 gaccgagcaa tgagtgctta tggacaagcg gtaggtgtga cgaatttcca aatgatgaaa
    11581 gctttcactt ctattgcgaa taacggtaca atgattcaac ctcgatatat cagcaaagtg
    11641 gtggatcccc aaactggaga agagcgaaca actcaaacag aagttctagg gcaacctttt
    11701 tcaaaagaaa caacagaaaa agtccgtgaa tatatgagag atgttgtcga aagcgaaaac
    11761 tacggtagtg cttatggtgt atatagtgta cctggataca atgtatcggc aaaaaacgga
    11821 acagcccaaa tcgcttctga tacaggggga tatcaaacag gagatacagc ctacctgtat
    11881 tcgattgtgg agatggttcc ttctgaagat ccagactatg tcttgtatct aacaatgaaa
    11941 caccctaaga catatgatcg aatggcattg gctaaaatcg caaatccatt gatgaaacgg
    12001 gcaatggatt ttaaagaaac tgaagaagat tcagatacag aaacaaaaac agaaaaagta
    12061 tccgtagccg attatcgtaa tcttgaagcg gacgttgcag cagctgatgc tcaaaaaagt
    12121 ggactgcaac ctgtagtgat cggtaatggt aaaaaagtac aaaaacaatc tactgccaac
    12181 ggtgatcagt tgatctctgg agaaaaactg atcctatata ctggtggtga taagctgatg
    12241 cctgacgtaa caggatggtc aaaagcagat atcatgaagc tggggaaaat cctcggtatt
    12301 gaagttagtt ttgatggaga tggttattgt gtcaaacaag aacttgctcc atatgaaaaa
    12361 atcactgaag acaaacttag ttttacttta gaagaataag aagagaaata ggagagaaaa
    12421 gagcatggaa tggacacaag cattgattcc cattgtcagc agttgtgcaa tgacaattgc
    12481 cgcaatgccg ctatttattg gttattttca aatgaaaaag caaggtcagg cgattcgtga
    12541 ggagggacca aagtggcaca atagcaaagc cggaactcct acaatgggcg gcttagtgtt
    12601 tctgatcggc tctattttga caggaatttg ggttggagct tggcaaaaac agctaactcc
    12661 tactcttttc atcttgcttt ttgtattagc gttatacgga gtaatcggct ttcttgatga
    12721 ttttataaaa atattcaaga aaagaaacat gggactgaac tcgaagcaga aattgattgg
    12781 acagattcta gggggaatca tcttttatct tgtttaccgt tctgaaggtt atccaggtgt
    12841 attgaatttc ttcggactag atctaccttt aggaatcatt tatggtattt tcgctctctt
    12901 ctggcttgtt ggattttcaa atgcagtaaa tctgacagat ggcatcgatg gattagttgc
    12961 tggcttagga agtatctctt ttgcagctta cggtctaatt gcttggcatc agcatcagta
    13021 tgatgtatta atcatttgct taagtgtttt aggaggttta ctgggtttct tcgtctacaa
    13081 cagaaaacct gccaagattt ttatgggaga tgtcggttca ttagcgttgg gcggactttt
    13141 agcggcaatt tctataatgc taaaccaaga atggacattg cttttgattg gtttgatcta
    13201 tgttatggaa acagcaagtg tgatgcttca agttacttcc tttaagctta caggaaaacg
    13261 aatttttaaa atgtctccaa ttcatcatca ctttgaaatg tgcggatggt cggagtggaa
    13321 gattgataca gttttttggt tgatcagcat tgtgacttcg ttgatcacat tatggatcgt
    13381 ttggtaggag atgacgggaa atgaaaaaaa tatcaacata tgaaaataag aaagtgcttg
    13441 tcttaggact cgcaaaaagc ggagtaagtg cggccaaatt attacatgaa ttgggcgcac
    13501 ttgtcaccgt taatgatgga aaaccttttg acgaaaatcc ggaagcacaa gagctgcttt
    13561 ctttagggat aaaagtaata acaggtagtc atccaatcga attgttggat gaagaatttt
    13621 cattgatggt caaaaatcca gggattccct acagtcatcc tttagtagca aaagcccaag
    13681 aaatgggtat tccggtaatt acggaagttg agctagctta cgaagtagcg gaatgcccaa
    13741 ttattgggat tacaggaacg aacggaaaaa caacgacaac aacgatgaca ggactactac
    13801 tgaatgcagg agcagatcaa ggaattgcac gtttagcggg taatattggg tatccagcaa
    13861 gtggtgtagc gcaagaagca aaatcagaag ataaaattgt gatggaattg tctagcttcc
    13921 aactcatggg aatcacagat ttccgccctc atatagcggt gattaccaat atctatgaag
    13981 cacatattga ttatcatggt acaagaaaag aatatgtcaa agctaaatgg aaccttcaaa
    14041 aaaacatgac agaaaaagat tatctgatcc ttaactggaa tcagtcagaa ctacaagaat
    14101 tagcgcaaag aacaaaagca cgcgtactgc ctttctcgac aaaagaagtg ttggaagacg
    14161 gtgtgtatgc tgacgattac tcaatatact ataaaaaaga aaaaataatg gaaatatctg
    14221 aacttggcgt accaggtaag cataatgtag aaaatgcact agctgctatt tctgtagcaa
    14281 aattgtatgg tatatcaaat gaagctatac gagaaacgtt gcattttttc catggcgtac
    14341 cacatcgtac gcaatatgta ggagaaatcc aaggcagaaa attttataat gattcaaaag
    14401 caaccaatat tttagcgact aaaatggctc taagtggatt tgaaacgtct aaggtcgtgt
    14461 tattggctgg cggattagac agaggaaata catttgatga attaattcct tcattaaaag
    14521 gaatcaaagc aatggtcgta tttggccaaa caaaagaaaa gttgatggat gctggaaaaa
    14581 aagcaggcat cgagacaata gtaacagccg attctgtaga acaagcagtt cctttagcat
    14641 tagaaaacag tacagatggt gatgtagttt tattatcacc agcgaatgcc agctgggatc
    14701 aatacccaaa ttttgaaact agaggaaaca gattcatgga agctgtgaac cgattaaaat
    14761 agaaaaagta gaagcgagcg ataaaaaatg aaaattttgg ttacaggcgg aggaacaggg
    14821 ggacatattt atccagctct tgcctttgtc aattatgtaa agactcaaga accgaatgct
    14881 gaattcatgt atgtgggagc aaaacgaggt ctagaaaaca aaatcgtccc tgatacagga
    14941 atgcctttcc ataccttgga gattcaagga tttaaacgaa aaatttccat gcataacatc
    15001 aagacggtcc gattgtttct taagagtatc cgtcaagcaa aaaaaatcct cagtgatttt
    15061 caaccagata tcgttatcgg tactggagga tatgtttccg gagcggtagt gtacgctgca
    15121 gccaaaatgg gtattccaac agttatccat gaacaaaaca gtgtaccagg tgttaccaat
    15181 aaatttttaa gccgatatgt ggatcggatc gctctttcat ttaaagatgc ggcttccttt
    15241 tttcctgaaa acaaagcagt tcttgtaggt aatcctcgag cacaagaagt agcagatact
    15301 aaaaaatcag atattttgaa aacatttgat ttggatccag aaaagaaaac agtcttgatt
    15361 tttggcggta gtcaaggagc acttaaaatc aatcaagcag tatcagtttt tttaagtgaa
    15421 tatattcctt cttcttacca agttttgtat gcttcaggag atagatatta tgaagagatc
    15481 ctaaataaaa taaatcctga aatacaaaat attagtgtcc agccttatat caaaaatatg
    15541 gcagaggtca tggcttccag tgatctgctg gtggggcgtg ctggtgcaac ttcgatcgca
    15601 gaattcacag ctctggggtt accggcagtg ttggttccca gcccatatgt tacgaatgat
    15661 catcagacta aaaatgcaat gagtcttgtt cacgcaggag cagcaaaaat gattgcagat
    15721 aatgaactaa caggtgaatc actaagtcag acagtcaacg aaatcatggg tgatgaagaa
    15781 ttgcaaaagc aaatgtgccg agcttctaaa gaacaaggaa tccctgatgc ttcaaaacgt
    15841 ctttatgact tagtaaaaca aataatcaaa aaataaaggc ggtggtctta gtgagtaaga
    15901 aaaaagaacc aaaaaaattg tctcatccgt cttctgatga aaacaatttg actccttggc
    15961 aaaaggctaa ccgaaaatat ctggcagaac aagagatgaa aaaccaagag ccaaaaaaag
    16021 aagacataac attagataca cccctttcag attctgaaga agaaaaaacg gttcaagagg
    16081 aacagcaaga agaaagccag tccgagaaaa aaatcgaatt ttttgaagag atcaagcaaa
    16141 agaaaaacgg tggaccatat aacggttctt ttttgaaccg gctgcccaat ttaaaaagtc
    16201 aacggcacaa agtactattt cgtcggttag ctttgatcat cactgtattg ggtataccgc
    16261 tgattttttt gatctattat gtttctcctt atagcaaatt acaagcagtt gcagtatcag
    16321 gcaataagac agtcaacagc caagaaatca tctctgatac aaaattgtca ttaggagaaa
    16381 atgtttgggg acagtatttt catcgatcta cttatatcga tcgccttaaa aaagcacagc
    16441 caagaatcga aacagcaaat atacatttca aagggatgaa tgaattcgat ttggatgtaa
    16501 cagaatataa agagattgct ttgatcgcaa aaaacaatca atactaccca gtgattgaaa
    16561 atggaacagt attagatgaa aaagtagcaa atcctacaaa aaatctccct atcttggaag
    16621 agttcaaaga ctctgcaaaa atcaaagaat taacaaagca atacaatcag ttatcatcag
    16681 aattacaaaa agcaatttct gaaatcaagt acacgccaag agcaagcaat aaaaatctga
    16741 tccaattgaa tatgaatgac ggcaatcaag ttattgtaaa tatcaataat cttgcgaacc
    16801 aaatgaaata ttattcgcaa gtagccaaag atatggatga aaaaggtgtg atcgacatgg
    16861 aagttggtat cttctcgcat ccttacggta gcactcaaga aacggaagaa tcgggccaat
    16921 cggaagaaac aactgaaagt gaagaaaatg cggatcaaac aaacgaatca agtgaagagg
    16981 cagaaacgca aaaagcacaa acacctggat cgtctagcac aaacggatca tctgattcaa
    17041 atgattcaag tgaaacaagt caaatagaag ataatccaag tacaactccg tcaagtttaa
    17101 atgaaaattg ataaaacaac tttaaaaagt aagaatgtac tttctaaaaa ccagtaattt
    17161 atggtagaat tggaagcagt gaatatatct attaataagt atattttaaa acggacgcta
    17221 gttgttcgct tgtatatgga atagtaagta ggagggaatc ccattcatgg caaaaacagg
    17281 aatgtatgta ggccttgata ttggaacgac atctgttaaa gttgtcgtgg ctgaatatat
    17341 cgacagccaa atgaatatta ttggagtagg aaacgcaaaa tcagaaggga ttaaccgagg
    17401 cattatcgtt gatatcgata aaacggtcca agcgatacaa cgagcagtac gacaagcaga
    17461 agaaaaagca ggtatccaga tcaaaggcgt aagtgtcggt ttgccagcaa acatgcttga
    17521 agtagaaaat tgccagggaa tgattgcagt taacggagat tcaaaggaaa tcaccgatga
    17581 agatgtcaga aatgtggctt cagctgccct tgttcgttca atacctcctg aacgtcaaat
    17641 cgtgtcaata ttgccacaag attttactgt cgatgggttc gagggaatca aagatcctcg
    17701 tggaatgatc ggcgtaagat tagaaatgta cggtctgttg tttacaggac ctaaaacgat
    17761 catccataac atacgtaaat gcgtggaaaa tgccggatta atcgtcaacg aaatggtgat
    17821 tactccttta gcgctgactg aatcaattct ttctgacgga gaaaaagatt ttggtacgat
    17881 cgtcattgat atgggtggcg gccaaacaac aacggctgtt atgcatgata agcaattgaa
    17941 gtttaccaat cttgaccaag aaggtggcga atttgtcact aaagatatct ctattgtatt
    18001 aaatacgtca tttaacaatg cagaagcgtt gaaaataaac tacggggatg catacccaga
    18061 acggacatca ccagatgaag aatttccagt agatgtgatt ggtcagtcag aaccagtgaa
    18121 agtcgatgaa cgctacttgt cagaaattat ttcagctcga atggaacaga ttttcaacaa
    18181 agcaaaagat gcattggacc aaatcgaagc attagagttg ccaggtggcg tcgtattgac
    18241 aggcggagct gctagtcttc ctggtgttgt ggacttggca caagaaatct tcggcgtaaa
    18301 tgtaaaattg tatgttccaa atcacatggg gctgagaaac ccggtattta caaatgtaat
    18361 aagtatcgtg gattattcag caaacttgag tgaagtgtat caattggcaa aaattgctgt
    18421 tacgggtgaa acctcagcag ctcgtcaaat ggtagttgaa caagaaacaa caaacacata
    18481 tgagagctat gaagcacctg aagaaacaat ctacgatgag ccggaaccaa aagagtccgg
    18541 agaaaatgta aaaaataaaa tcaagggttt ctttacaaat atttttgatt aattcatcct
    18601 gggaggaata agatatggaa ttctcaattg ataataatat caatgacggc gcagtaatca
    18661 aagtcatcgg agtcggtggt ggcggtggaa atgctgtaaa ccgaatgatt gaagaaaacg
    18721 ttaaaggtgt tgaattcatt acagccaaca cagacgtgca agcattaaaa aattcaaaag
    18781 ctgaaacagt tatccaatta ggccccaaat atactcgtgg tttaggtgct ggttctcagc
    18841 cagaagttgg acaaaaagcg gcagaagaaa gtgaacaatc cttacgcgaa gctttagacg
    18901 gtgcagatat gattttcatc actgcaggaa tgggtggagg aaccggtaca ggtgctgcac
    18961 caatcgttgc aggtatcgcg aaagaattgg gcgcattgac tgttggtgtc gtgacacgtc
    19021 cattcacttt tgaaggaccg aaacgtggcc gttttgctgc agaaggtatc gctcgtttga
    19081 aagaaaatgt ggatacatta ttaattatct caaataaccg tttattagaa gttgtagata
    19141 aaaagacacc gatgcttgaa gctttccgtg aagcagataa tgttttacga caaggtgtac
    19201 aaggtatctc tgatttgatc acagcgccag gttacgttaa ccttgacttt gctgacgtga
    19261 aaacagtgat ggaaaaccaa ggtacagcat tgatggggat cggtgtggct agtggagaag
    19321 atcgcgtagt agaagcaacg aaaaaagcaa tctcctctcc attgcttgaa acatctattg
    19381 atggagctga acaagtactt cttaacatca caggcggttt ggatatgaca ttgttcgaag
    19441 cacaagatgc ttcagatatc gtagcaaatg cagcaactgg cgatgtaaat atcattctag
    19501 gtacatctat caatgaagaa atgggcgatg aaatccgtgt gacggtcatc gcaacaggta
    19561 tcgatgaatc aaaaaaggaa cgcaagtcta gccgaccagc tagacaagca caaatgcaat
    19621 cacctgctca aaagactgta ttagatatgg atcaagctaa accaacttct tcagaagaag
    19681 aaaacagttt tggcgattgg gatatcagac gtgaacaaaa tgttcgtcct agagttgatg
    19741 attccaattt tgacaatatc gaaaaaaaag aatttgatac attcaaccgc gaagaaacaa
    19801 aatctcatgg cgatgatgaa ttaaatacgc caccgttttt ccgtcgtaaa aaataaagga
    19861 gaggaagagc acatgattgc tgacaacttg cagaaaatca agcaagaaat tcaggattcg
    19921 tgtgctcttg ttcatcgtga tccgaaagaa gttacattag tagctgtaac aaaatctgtt
    19981 gaatccgctc aagctgaaga attggttaga gctggcgtta tgaattgtgc agaaaaccga
    20041 gtagataaat tattagaaaa gaaacaagat ttatttgatt ttcctgaaat aaagtggcat
    20101 ttaattggta atttacagcg cagaaaggta aaattgattg taaatgaaat tgattacttt
    20161 catgcgttgg acagtttaag attagcagaa gaaatccaga agcggttaga gaaagaatta
    20221 tcctgtttta ttgaagtaaa tgtttctggt gaggaatcaa aacatggaat ttcaccagat
    20281 gagcttttac cgtttgtgga atctttagct gcctgcacaa aaatcaaggt tgttgggttg
    20341 atgactatgg cgcctaaaga agcttctgat gagcaaatcc ataaagtgtt tggtacgctg
    20401 aaagaattgc gtgatcttgt tcaagcaaaa ggttatgccc atgcaccatg tagtgaatta
    20461 agtatgggga tgagtcaaga ctttcaaatt gcgattgaag aaggtgcaac atttatccgt
    20521 gtaggaacag cgctattcaa agacgaataa aggaggaaca aaaatgccgc ttttaaacag
    20581 aggagcaatt gctaattttt tcggattagc tgatgaggaa gagtacgaat accaagatta
    20641 tcctgaaaca acaaaaaagg ctgtacagcc aactaaaaaa aatacaacac agaatcaatc
    20701 aactcattct gtatctgctg cgaatactca tgaaaaacaa aaaacggcga cttcacgtcc
    20761 tgtaacgcat gaaagtattc agccggctga aaagaaaaaa gtaattgaac tacatcaatc
    20821 acctacaaaa actgtagcga aagaaagaac agcttcaaga acctctacac aacctaaagc
    20881 aaatcttgct ggaaaaatca ctgtaatgga accaagagct tattctgaag ctatggcgat
    20941 tgctaaacga atcattgctg gagaagcaac cttagtgaat tttcatttag tagaagaaaa
    21001 acaagcgaga agaatcgttg attttctaac aggaacagtt tatgcactag atggagatat
    21061 caaacgtgtt ggagatgaga tttttctttg tacaccgact gggatggaga ttgacagttc
    21121 aaccgctcaa tcttttgcag atgcgaattt gtttgatctg taagaggagg aactacgatt
    21181 tatactattg cactattact tcatttactt caacgggcag cctatttcta tagcattatc
    21241 ttgatggtat atgcattgct ctcttggttt ccaggcgggt atcaatcagg gctaggacga
    21301 ttattagcta agatctgcga accgtatatc agtttgttcg atcgtctgcc tttgaggatt
    21361 ggacccttgg atttcacaat tttaggggca atcctgatct tgaacttagc cgtacaaggt
    21421 ttagcacaga tcgttatatg gataactgtc catttagttt attgattgaa gcaacaaaat
    21481 ctttattctc agaatagata ggaggggaaa attttggatg caaatgtata ccagcacttt
    21541 cgggcagatg aacgtacatt tatcgattcg gtaggcgatt ggattgaaca ggttcaagga
    21601 caatatgcac cctatctgac cgaatttctt gacccaagac aatcctatat tttagaaaca
    21661 ctgattcgac aaagcagtga tttgcgtttc atgttttatg gcggatatga acaggcagaa
    21721 agaaaaagat gtttgatttt ccccgattat tacgaacctg tagaggaaga ttttgaaaca
    21781 gcattgtatg aaatccatta tcctagcaaa tttgccagcc taagtcatgg gaaaatcctt
    21841 ggaactttag tgggaacggg gatcaaacgc tcttactttg gcgatatcat ctcggacggt
    21901 gatcgctggc aagtatttat tgcaaatgag gtggatcatt ttgttgctgc acaagtaaca
    21961 aagattggaa aggttgctgt acgcttggaa ccaatcaaat acacagaaat gattatgccg
    22021 aaagatagct ggacacaaga aagaggaaca gttagttcca tgcgactaga cagtgtgatc
    22081 tctgagattt ataatatttc cagacagcgg tccaagcagc tgatcgaagc tggtaaagta
    22141 aaagtgaact ggacagaaaa tacaagacct gattttgtac ttgaactatt agatattatt
    22201 tcagtcagag gttatggcag agtccagatc caagaacttg aggggaagac gaaaaaagaa
    22261 aagtacaggg tactgttcgg tgtattacgt aaataaaata aaaaggtggt ttactcatgg
    22321 ctttaactcc attagatatc caaaataaga cattcccgac aaaaatgcgg ggatataatc
    22381 aagacgaagt agatgatttc ttagatttag ttgttcgtga ctatgaggaa ttgactcaaa
    22441 gaaatcgaga attagaaaaa gcagtcaaac attctgaaga aaaacttgag tacttcaatg
    22501 aattaaaaga tgctttgaac caatcaatca tcgtagctca agatacggct gataaagtaa
    22561 aaacaagtgc aagcaaggaa tccgaagtga tcgttacttc tgcacaaaac aaagcagatg
    22621 agttagttgc gaacgctgaa aaacgtgcac atcaattaac aactgatgca gaagaaaaag
    22681 caagaaaaat cttgacagat gcaacagaaa aagcaagaca gcttgcgaca gaaactgaag
    22741 atcttaagaa aaaaacacga gtattccatc aacgtatcag cttgatgctt gagtctcaat
    22801 tagaacaagt gaaaagtccg gaatgggatg aaattttaca accattctcc agctacgtga
    22861 ctgacagcca tgaagtgatc aaagaagttt tagcaaaaca gcttgacaat gaaaatgata
    22921 ctgatgtaaa ctcagacaca ggagtcatag aagcacctat gacggcattt gatacacagg
    22981 ctattgatat ctcgatcgtg cctggtgaaa atgaaaacga gtagaacaga aaagcacttt
    23041 gttattctta aagcgagccg atgagagtgg aagttcggta agacactgca tggtgaaaga
    23101 tcctctactt gagacctgct tttccgaaat tagagtaaga agcagcggct gacctcgtta
    23161 ttggtcacag agagtttgca ctagatagat gcaactaaat ttgggtggta ccacggcatg
    23221 ttcgtccctt gcggctgaac atgctttttt gtgtccggaa aacaaataaa ggagtgtatg
    23281 gttgaatgaa aatgaaagaa accttgcaat taggaaaaac aaaattccct atgcgtggta
    23341 atttgccaaa ccgagaaggc gagtggcaaa aagaatggga agaaaatcga atctaccaaa
    23401 aaagacaaga gttgaacgaa ggaaaaccta gctttgttct tcatgatgga cctccatatg
    23461 ccaatggtaa tatccattta ggacattcat tgaataaaat cagtaaagac attatcattc
    23521 gttcaaaatc aatgtctggc tatcgtgcac catatgttcc aggatgggat acacatggat
    23581 tgccgattga acaagtattg gctaataaag gcgtgaaacg taaagaaatg tccatggcag
    23641 aatacttgga aaaatgtcgt gaatatgcac tttcccaagt agataagcaa cgagcagatt
    23701 tcaaacgcct aggagttgca ggagattggg aacatcctta tgttacatta gatccttctt
    23761 atgaagctgc acaagtacgc gtatttggta aaatggctga aaaaggctat atttacaaag
    23821 gattgaaacc aatttactgg tctccgtcaa gtgagtcttc tttagcggaa gctgaaattg
    23881 aatataaaga tgtaaaatct ccatctattt ttgtagcttt caatgtcaaa gacggcaaag
    23941 atattcttga tgaagataca gcttttgtca tttggacgac aacaccatgg acattgccag
    24001 caaaccaagg tattgctgta aatccaaaat ttacgtatgt attggtggaa gccgatggcc
    24061 gtaagtttgt cgtagcgaaa gatttgctag aaacagtcca atcagaaatc ggttgggaaa
    24121 atgtaacagt tctaaaagaa tttgctggac aagaaatgga atatatgact gcaagtcatc
    24181 cattctatga acgtgaatca cttgtgattt taggcgatca tgttacttta gacgctggta
    24241 ctggattagt ccatactgct ccaggacatg gggaagatga ctatatcgct ggtagcaaat
    24301 ataaactatc tgtagtgtca cctgtagact caaaaggatt gtttacagaa gaagcacctg
    24361 gatttgaagg tatcttttat gacaaagcaa atcctatgat cactgatcta ttaaaagaaa
    24421 aaggagcttt gctgaagcta gatttcttta ctcatagtta tcctcacgat tggcggacga
    24481 aaaagcctgt gatctatcgg gcaactccac aatggtttgc atctatcgat aaattccgtc
    24541 agaatatttt ggatgaagta gaaaaagtag agtgggttat cccatggggt aaaacacgtt
    24601 tgtataatat gatccgtgac cgcggcgatt gggtaatttc ccgtcagcgt gcatggggag
    24661 taccacttcc gattttctat gctgaaaatg gagaagcaat catcacacca gaaacaatcg
    24721 aacatgtggc aaaattattt gctgaacatg gatcaattat ctggtttgaa aaagaagcga
    24781 aagaacttct tcctgaagga tttacccacc caggttctcc taatggcgaa tttacaaaag
    24841 aaaaagatat catggatgtc tggtttgatt ctggttcttc tcatgaagct gttttacgtc
    24901 agcgaccaga attatcattc ccagcagata tgtatttaga aggatcagac caatatcgtg
    24961 gctggttcaa ctcaagtatc acgactagtg tggctatcaa tggtgtagca ccatacaaat
    25021 cagttatttc tcaaggattt gctttagatg gtgaaggccg taagatgagt aaatctttag
    25081 gaaacatcat tgcaccagaa aaagtgatca aacaatttgg tgcagatatc cttcgcttat
    25141 gggtatctag tgtagattat gaagcagatg ttcgtgtttc tatggatatc ttaagtcaag
    25201 tggcagaagt atatcgtaaa atcagaaata cgatgcgttt cttattagcg aatacagaag
    25261 atttcgatcc taaaaaagat actgtttcgt acaatgattt acgttctgta gacaaatata
    25321 tgaccgttcg attgaaccaa gtaatcaaag aaatccgaga agaagggtac gacaaatata
    25381 acttcatgca tatttaccgt acagttatga acttcttgac ggttgatcta tcgtcattct
    25441 acctggattt tgctaaagat gtagtttata ttgaagcaga agatgattat caacgtcgtt
    25501 gcatgcaaac tgttttctat caaacagctg tagctttgac aaaattattg actcctatca
    25561 ttccgcatac agcagaagaa atctggtcat tcctgaaaga agaagaggag tacgttcagt
    25621 taagcgagtt tcctggttat gaagagtttg caaaccaaga agaattgatg gatacctgga
    25681 ctgctttcat ggacttccgt gataatgtct taaaagcatt ggaagaagca agaaacagca
    25741 aattgattgg taaatctttg gaagcaaaac taactgttta tccaaaacaa caagttcgtg
    25801 aaatgttaaa agctttggat gcagatattg cacaattatt gatcgtttca ccagactact
    25861 ttgaagttat ggcagcagat gaacaagtgc cagataacgc tatggtattt gatgatgttg
    25921 ctattacagt ggaaaaagca gacggggaaa cttgcgatcg ctgtcgccaa gttcgtaaag
    25981 atgtaggagt agatgaaaaa cttcctcatc tatgcggtcg ttgtgcaaaa atcgttgaag
    26041 acttctatcc tgaagctgta gctgaaggat tcgaagaaaa gtaaaaggga aaagggggtg
    26101 tgacatgttc tttgtcacac ccccttttgt tatcaatcgt ttaattttcc acgttcacga
    26161 taccagttat ctggttgcca gatccattcg aatccgtctt tttcaagtag ttcgaaagct
    26221 gctttaggtc ccattgatcc agctttgtag ttgggaaaat ccggttgtgt ttggtcccaa
    26281 gcttttcgaa tgacatccac gatatgccaa gattgagcga cttcttccca atgagagaag
    26341 ttcgttccat caccattcaa cgcatctaat agtaattttt cgtaagcttc tgggctattt
    26401 tcaaccattt ctgcactatt tctaaattcc aatttgattg gttccgtttc aaatccttgc
    26461 cctacttctt tcccattcaa ggataaagaa aatccttcag ttggctgaat atagatcgtt
    26521 agaacattag gtggaagtgt cgtatcgtca catggttcat cgacagatgt tttgaataca
    26581 ttaacaggaa cttgtttgaa tacgatgttg atccgagtcc ctttttcagt caaacgtttg
    26641 cctgtacgta catagaaagg aacacctgac caacggaagt tatcgatagt gaatttgcct
    26701 gcgacgaatg tttcagtctc tgattgagca tccactttgt cttcttcgcg atagcccttg
    26761 aattgtacac catccaattc accttgagca tattgcccgc gaacgaagtt ttctaacact
    26821 tcttcttcgt tataaatgcg gatagctttc aatgctttga tcttttctgt acggatttct
    26881 ttttcggaaa atgctactgg cggttccatt gcaagtaatg ctacaacctg taaaatatga
    26941 ttttgcacca tgtctttaag tgcgccacta tgatcgtagt agcccccgcg atcttctaca
    27001 ccgaggtttt cgccaaaagt aatttggata ttgtcgatat agcgattgtt ccattgagcc
    27061 tcaaaaatat tattggcaaa acggatagct gagatgtttt ggatcatttc ttttcctaaa
    27121 taatgatcaa tcctgaaaat atcttgttct gggaatactt ctctgatttg ctggttcaat
    27181 tcaaaagcag actggtaatc agaaccgaac ggtttttcta tgatcaaacg attgaagcca
    27241 ttttttgtca taatattttg tgatttcaaa tgagaaacga tcgttccaaa aaattgaggt
    27301 gccatagcca aataatagac acggttaccg tttaattgat agtgtccatc taatcggtca
    27361 gacaattctt ttaatgtctg ataatgcgtt gaatcattta catcatggga ttgatagtaa
    27421 aaatggcttg caaaggtagt tgcttcttca tctgaaggat tcaatgcacg gattgtttct
    27481 ttgacaactt cacggtagtg ctcatcgctc cagggacggc gagcggttcc gattacagca
    27541 aaatgctcgc ctaaatttcc ttttctgtaa aggcggaaca aagacgggta caatttacgc
    27601 tgggctaggt cacctgtacc gccgaatatc gtaaacaata catttttttc attagacatg
    27661 tggatacact cctttatatt ttatcgacaa aaatcgtgct ggccgcctta aagctgacgg
    27721 ggattttctt tctatcattt tggatagtga tcggtccttc ataagctgcg atgtcaacga
    27781 tctcatattc ttcgttgata ttcaggtcaa tagtgactaa gtaatccaac aattcttttt
    27841 catcaagcac tcgtgcgata cgcacttttg taccgacagg ataggactcc aatgtttgtc
    27901 ggcgttcttc atggacaact tcctcttttt taggaatcga tcctccatga ggacaatgtt
    27961 caggatgatt caaatagttt tctaaatgat ctgcaagatg ttccgaagtc acatgttcca
    28021 atacttcagc atcatcatgg acttcattcc agctatagtc taaatgttca actaaaaaaa
    28081 cttcccataa gcgatgtttg cgaatcagac tgctagcttt ttgcagtccg cttgcagtca
    28141 attgtacacc ttgataaggg gaatgttcta caagctcttc tttcacaagt ttagaaatca
    28201 tttcactgac agatgcagct gagacatcta gactagatac gatttgttta ttgttgactt
    28261 tcgttgtatc tccacctagt tctaaaatga ttttcaaata atcttctcga tttggtgtca
    28321 tattcgatca tcctttcatg gtaaaaaacc atcattagta agtgtaacaa aaaaaacgtt
    28381 aattgactat ttttctaaat aaaaaacaaa ggatttttag acgtttttac aacaaaaaac
    28441 gaaagatgat agagaagact cattctttcg tttataaagg atatatatat acattgggag
    28501 ggatctattt ttcagataac aacttatatg aagtgtctgc agattcgtca taaagagttt
    28561 gttcgggata agaaaagata agataaaaac catactgatc acgtacgact aaacgatatt
    28621 catctatttc taccacagat gtgccaagag actgaccgtt gatcaaaaac gtgtaatcag
    28681 atgtaatctg taattgttgt ttttgctggc tatcactaaa gaaccatgta ccttgatact
    28741 ttgagagtcc ttctgacttt tccgcttgtt ttttcttttt caagtaaata aaacttgaga
    28801 gaacggtaat gagtgaacca agaaaataga tcattttttt tatcaccaaa tcactccttt
    28861 atgagaaaat aatcgcatag acatattctt tcttctttat ttcattgtac cgaataaaag
    28921 ctaaaatttc tctaagactt tcgactggtt tttttactgt ttttctacaa attatgatag
    28981 gatacatagt aggaagaaag gtgacataat ttgaagtatc agcaagtgga aatagctttt
    29041 tttattgacc gcccgaatcg gtttatagca cattgtatga aaaaagacgg agaaataatt
    29101 attgcgcatg tcaaaaatac aggtagagga aaagaggtcc tgataccagg cgctgaagtg
    29161 gctattgtat ttgctcctgg acctaaacgg aaaaccgcct atgatctgat tgctgtaaaa
    29221 aagaagggtg actggtttaa tatcgatagt caattgccta atcggctggc aattgatggt
    29281 attttagacg gcacgatcct tttaccagga ttaactggtc catttacggt atacaagcgt
    29341 gaagtaactt atcttcactc caaatttgat atttatttag agacggtggt cggacaaaaa
    29401 gcatttgttg aagtcaaagg tatgacactt gaaaataaag cgattggtgc ttttcctgat
    29461 gcgcccacac tcagaggatt gaaacatata ggagaattaa cgtatgccgc acaagatggt
    29521 tatgccgctt atgtcttgtt tattgctcag ttcgaacatc ttcatctggc aacgatccat
    29581 gaagaaatgc aaccagcact agctgatatg gttcgacatg cgcagcaaag cggagttcaa
    29641 atcctcgcct ataattgtca agtatcggca gatgaggtaa ctgtcaagca ggccattcca
    29701 tttgatgtag atatcccttt tgaagatcct atacaataga aagaaggtaa aataatgatc
    29761 aacttaggta ttatcggaac aaattggatt actcatcaat ttgtccaagc agctttaagc
    29821 acaaaaaaat atgaattgac agcggtatat tctagacatt tggaaaaagc acaggaattt
    29881 ggttctcatt atgaagggga tatcgaattc gcaacagatt tgaagacttt tttcaatatt
    29941 actcatatgg acaccattta tattgcttct ccgaatagtc ttcactttag tcaagctaag
    30001 caagcaattt tggcaggaaa aaatgtgata gttgaaaagc cagctttttc gacgccaaaa
    30061 gaaatggatg aaatcatcca tttggcaaat gaacacaatg tgtatttttt tgaagcagca
    30121 agaaatatcc atgaatcagg ttttaaaaag attgccgatt acttaccatt aaaagacgag
    30181 ataatcggtg caaatttcag ctatatgaaa tattcttcgc gctatgacca agtattagat
    30241 ggagaagaac cgaatatctt ctcgactcat ttctcaggtg gtgcattgat ggatttaggt
    30301 gtttaccttg tatatgcagc tgttgcttgg tttggaatgc caaaagaagt ccattatttc
    30361 ccaagaaaga tttctactgg tgtagatggt cttggatggg ggatcttacg ttatgagaat
    30421 tttgatgtat cgatccagcc aggtaaaatc ggtgattctt atttaccgtc agagatttat
    30481 tttgactcag gaacgctagt gatgaatgga gtcaatgcaa ttgaacaagc acaatttcat
    30541 gatcgcgcgc ataaagaaat cattgatttg gcggtaacag ctgcagaaaa tccaatggca
    30601 gatgaagcag aggattttgc caatgtcatg gctcatccga aagatccagc ttggggattg
    30661 ttgtatgaag agtggatcga gctagctaga aatgtgaacc aagtgattta tgatttaaga
    30721 aaaaatggcg gcatcaaatt cgatgcagat aatgaggaag atttttaatg aacgaatttg
    30781 tacaagtatt tcccgaaaat tggcagaaaa aatatgagga taaagggttt atctcacctt
    30841 ctcttattca acgagcagtt tttcagccac taagtaataa acaaagtata gtagcggttt
    30901 ctcctacagg ttcaggtaaa acactggctt atctttggcc tctactacta aacgtggaac
    30961 caggtgaagc aagtgcgttg gtcatttttg cttcttctca agaactagct attcaagtag
    31021 cagatgttgc acgtgaatgg ggaaaagaca aagagttgaa agtccaatct ttggtgggcg
    31081 gagccaacgt caaacgtcag attgagggtt tgaaggaaaa accagaaatc ttgattggta
    31141 caccaggaag aatattggaa ttgatgaaag caaaaaaaat aaaagcacat caagtgaaaa
    31201 caatggtatt tgatgaagca gaccagctat ttgacgctgg gaacagccaa atcattgatc
    31261 aaattcttca tcaagctcca acagagtatc agctagcttt tttttcagcg acagcagatc
    31321 gttcccttga aagcattgaa aaaatcactg ggaaaacgtt tgagacaatt gacgtgacag
    31381 cagaggacga ttctcgaaaa ggactgagac attacttttt acgtgtaccg atacgaaaga
    31441 aagatgacta cttgagacgt ctcacgcata tagaagattt tcatggtctg attttcttta
    31501 atcaactgac tgaattaggc gtaatggaag aaaaattgct gtatagaggt gtaccggtag
    31561 gaagtctggc ctctgatcag aacaagctac tccgaaaagc agcgctagaa caattcaaaa
    31621 agaaaatggt cagagcactt ttgaccacag atgtggcggc tagaggttta gatattacag
    31681 gtcttcctta tgtagtgaat gcagaagttc cgttaagtga agaagcttat ttgcatcgtt
    31741 cgggaagaac tggtcgaatg ggtaatgaag gaatagtaat tacactcgta caagataata
    31801 atctaagaga tttaaaacgg cttttacgtc catcaaatat aacacttgaa gagatttttt
    31861 tatacggagg taagctgcaa actgagcagc caaccaaaga agatgcagct cctgcagtaa
    31921 ataaaaagta tgcgaaaact ttttctggaa aggagcagaa cccagaatat aacaaagaaa
    31981 aaataagaaa aaaagttaaa aataaatcaa aaaaagagag aaataaagga gcaaggcgca
    32041 aataagcgcc tttttatgct atgattatga aaacgggaac aaaattggtt gccagaggag
    32101 gggttatgtg aaagaacgtc aagaagagat cttgcagcta ttgacagaaa accaacaagg
    32161 attgacagca agtgatgtag ctgagcgctt aactatcgat cgaagcaatg caagccgata
    32221 tttaagtgaa ctatacaagg cccatcatat tgtaaaaacc gctggccgac cagtcgttta
    32281 ctctttgcca acggaaaagt caaaatctga tgaagtgcat gtcgactctt ctacgcaagt
    32341 gacttttgaa acactcgttg gagaaaatga ttctttaaaa gtcagcatac agcaggcaaa
    32401 agctgcgatt ctttatccac cgcgggggtt gcatacgatt atttttggag aaactggtac
    32461 agggaagtcg atgtttgctg aatgtatgta tcattttgca atcgattcag agatgctttc
    32521 tgcagatgcg ccatttgttt ctttcaattg tgcggattat gctcaaaatc cgcaactgct
    32581 ctttggacac atctttggga tcaaaaaagg ggcttacaca ggagcagctc aagatagtcc
    32641 cggtctaata gccaaagcag acggcggtat attgttttta gatgagatcc accgtttacc
    32701 gccggaaggg caggaaatgc tgtttacttt cattgataaa ggtatttacc gtccgcttgg
    32761 agaaagtgca caagtacatg aagcatctgt tcagatcatt ggggcgacga ctgaatcttc
    32821 agaaagtttc ttatctacgt tcaatcgacg gattcctatg gcaatcacct tgccgaatct
    32881 tgcttcacgt tcactggatg agcgttatga aatcatctct ctttttatca aacaagaagc
    32941 gaatcgtttg aatcaacgta tcgatatcga aaaagaagcg attcttgcct tcatgcttta
    33001 tgatgcggaa ggaaatatcg gtcaagtgaa acgagacttg aaactagtct gtgcaaaatc
    33061 ttttttacat taccgtactc atcatgagaa aaagctaatc attcgaaaag aagaactttc
    33121 ccttcaagta caaaaaggat tactgaaaat caaggaaata ccggaacgtc tcgaccgatt
    33181 catggacagc aaaagtcagt atttgacatt tgaaccagga tttgctgatg ttgtctggtc
    33241 acaagatcca gaacgaaaca tgcaggtcta taacgatatt gaggaaaaag tcacttctct
    33301 ttccgaaacc ggtgtggaga acattgatct agagaccctc atttcaaaag atgtggatgc
    33361 ttatttccag acatatgtca aagaattgac taaaagttcg attcccaaag atcttttgcc
    33421 agatgaaatc tggcggttaa ccaatcaatt gtatgatgtg gctgaaaaac ggttagaccg
    33481 tatttataat gaaaaagctc gttttgcttt tgctttgcat ctgcaaagta cattggatcg
    33541 tgtgagagaa ggtcatatga tcgtccaccc agatttgaat aacgtacgga aaaattttaa
    33601 gagggaattc caggtagcaa tcgatctttc aacgatcatt gaagaagaag aacaagttga
    33661 gattcctttt gatgaaatcg gctttattag tatgtttctt tctatcaatc taggagaaag
    33721 tgagcctgtt aaagaaaaca aagtagatgt tctcatattg atgcacggca gacagactgc
    33781 ttcaagcatg ttggagatgg cacaagaact attaggaaca aaagtaggga aagcttttaa
    33841 tatgccactg gttatggaag ttcaaacaat gtatgaagaa gtgttacaat atgtcaaaaa
    33901 ctatcaagag catttgacga atggcctact cttgttaaca gatatgggat cattaaacac
    33961 cttcagtgat ttgatttatg aagagactgg cattcggacg aaagctatca cgatgacaag
    34021 taccatgatt gtgatagaag cgatacggat ggcaagtgtt ggaagaagct tagaagatat
    34081 ttatcaaaat atccagcttt cctttgaatc gatcgtacgt gatcagttca aagcggaaaa
    34141 gtctgaaact ttacagcgta aaaaagccgt aatcgtgaca tgctttactg gtgaaggagt
    34201 agctgccaaa ttatatcagc gtattatgcc agtgattaat caaaataagg tagaactgat
    34261 ccagatgcag tttttagaac gtgaatcatt caaaaaacac atcgatgcct tattggaaga
    34321 atatgagatc aaagcaattg cgggaacagt tgatgttgat tatcaaaata tcccattttt
    34381 ttcagcctat gacgtttttg atgatgaaaa actaaatatt ttaaagcgta tagctgatga
    34441 tgagatcccg acagctaaaa ttgtcgattc acttgctgga tcattaagcg atgtcttttc
    34501 tattgatgaa ctgatccgtt cattgcaaaa gacagttcag cagatccaga ccgatttgtc
    34561 gattatcgtg gaacctggag tagatactgg aatcgttatc catttagcct tcatgttaga
    34621 cggattgatc aaacaagaaa gccatcggca atttgagaaa ctgtctattt tctcaaaaat
    34681 ttatcgtttg gaaatggata tcgttcgggc aaacttgatg gcactagaac gaaaatatca
    34741 ggtaaaaatt ccagaagatg atatcgcatt tcttacacaa atgtttcttg aaaataaaat
    34801 aaaaaaatga acacactaat catactgttt acacactaaa catctgtgtg cgcactataa
    34861 aaaagagcta aaaagcatga aaacgctatt tcagctcttt tttttattgg catgcttctt
    34921 gcgttatata aaagtgtaaa aaaataaaag gagtgttaaa aatggcaaaa aaaacaatca
    34981 tgttagtttg ttcagcaggg atgagtacga gtttattggt cacaaaaatg caaaaagcag
    35041 cagaagaaaa agggatggaa gccgatattt ttgcggtctc tgcctcagat gcagataata
    35101 atttagaatc taagaatgtc gatgtattat tattaggtcc tcaagtacgt ttcatgaaag
    35161 ctcaatttga acaaaaactt gcgcctaaag gtattccatt agatgtcatc aatatgcaag
    35221 actatggcat gatgaacgga gaaaaagttc ttgcacaagc agaaaatcta atgaaataaa
    35281 tcaagtatgc agttgggggt ataacaacgt ggaagatcaa caaaatctag aagccatcat
    35341 ggggttaatc atgtttggcg gtaatgcaaa gagcgatgca atggaagcga ttgcggctgc
    35401 taaaatcggt gattttgagt tagcggatag gaaaatcgct gatgcagaag aatcacttat
    35461 acaagcgcat catgcacaaa cagacatgtt gacacaagaa gcacaaggaa atcatatgca
    35521 agtgacatta ttgactgttc acagtcaaga tcacttaatg acatctattg cgtttactga
    35581 tttagcaaaa gaaatcatcg aactttatcg tcgcgtatac agcgaataaa tacaacttct
    35641 tttttgaacg gaagaagaaa aatttttgaa cggatttttt attttgttat aaggagaact
    35701 ctctttatat aaaaaactta taggaggaag taaaaaatga acggactatc aagttggatg
    35761 gagaaataca tcctgccggt tgccgcaaaa atcggagcgc aaaaacattt agttgctttg
    35821 cgtgatgctt ttatcggcat actgcccgca acaatggcgg gatcagtcgc tgtaatgatc
    35881 aatgcaatta ttcgtgattt accgcaacag tttaacagta cctatgctga cagtttagca
    35941 gcagacaaag gaatctttgc cgtattgaat gtcatcatcg gaatcaatgg ttttgtctgg
    36001 aacggtacac tagcaatcgc cggattgatc tttgcctttt cttgggggta taatcttgcc
    36061 cgagcttatg gagtaaatga tctagctggg gggatcgttg gtttagctac cttgattcaa
    36121 ggtatttcct ttggtccagc attatcagca gcattagatg tgaatgttcc ttcaaatgtc
    36181 gcagatgcaa tcaatagttc tgagattggt gcaacgattg cagatggcac actgtcagtt
    36241 ggattatggg gttggctaaa actagatcat ttgaatggaa acgcttattt tacagttatg
    36301 atcatgggag ctatttcagt cattattttt tgtaaattga tgcttgccaa cattacgatc
    36361 aaaatgcctg attcagtacc accagcagta tctaaagcat ttgcagccat tttaccagcg
    36421 acgatcgctt tatacgtcat tgctattatc aattatatcg taggtcgtgt agctgatggg
    36481 caactgatca ttgatttggt gcaaaaatat attgcagaac cattcctagg attatctcaa
    36541 gggttgggag cagtattgat cgtcacagta tttgttcaag tattctggtt ctttggtatt
    36601 catggatcaa atgtattggc accagtgcta gagggaatct ggggacaagc acaactaatc
    36661 aatattgata ttttccaaaa aggttataac ggaaaaactg gtacaccagc cgtgttagat
    36721 gcaatcgaag atggaaaagc ttatatgtgg gtccgcggat cgttcgatgc ttttgcatgg
    36781 tttggcggat caggcggaac gatcgtctta ctgatagcta tcttgatttt ctctaaacgt
    36841 gcagattatc taacagtagc taaattatcc attgggcctg gtatcttcaa tatcaacgaa
    36901 ccagtgatgt ttggtctgcc aatcgtattg aatgcaatca tgtttatccc attcttgatt
    36961 gctccagtag tagcaacagc aattggatgg acagctactt atcttggcct agtcgctccg
    37021 gtatcgcagc aagtcacatg ggtagtaccg ccgttcttat tgtcattctt agcaacagga
    37081 gcggattggc gggcaccgat cgtaacatta gtatgtatgg tcgtgacttt cttgatttgg
    37141 gcaccatttg tcatctctgc aaacaaaatg gaccctgccg caggcgaaca acaataagat
    37201 gaacgtgagg agcgggacgc tttaagtttc gttcctcata atgaattttc gaggaggaac
    37261 tgaaatgatt acaattgcca gtgcaatgca acaagatgaa atcaaagaat tgttagaagg
    37321 atacaatgaa gaaggaatga cttttacatt taaagaaaaa caaggaatca agctgttctt
    37381 tgaaacaagt gcagaagatc cggaagttgc ggctaaaaaa gcaaaggaac taatcaaagc
    37441 acagccttgg ggaacagtcc tttattttca atcaacagct gtttagaaaa tggtttaaaa
    37501 agataggatg gttgagatga taaaaaacgg tttattttta tgtagtattg gttctttgat
    37561 cgtgttgtat agtttgaatc cacattcgca aaggtatgat ttgtatagta tggtcacagg
    37621 tctttttcta acaggattag gaatctattt cttcatgaag gggaaaaaaa gagaagaagc
    37681 aaaggagaaa aataactaat ggaaatcacg aaaaaattaa atattccagc atcgtttttt
    37741 tacgataaag ttatggactc tgtccttttc gatgtacgta aagcgaccgg caaatcagta
    37801 actagaaaac agctgaaaaa tttggagtac gtcaaacaat tctcgcaaaa taaccgggct
    37861 cgcataaaaa tcgaagaagt cattgaaaac cagtcttata agtttcgtac atcgacaacg
    37921 aagaatgaat tcgtcgttca ttatcaaatc aaaccattgg acgattcgac ctgtgaggtt
    37981 cattacacag aaaaaatgga gtcttatggc atgcttcaaa agttgaatga tatgctttta
    38041 ggaacaatct tgatgtattt taaacggaga cgtttcaaaa aaatgctaga tatgatcgaa
    38101 gcaacgtatt aaatcaatga aacatggtac tatttagtta ttgaaaaatg aagtaagcta
    38161 gaaggaattt ttcataggaa gatagatctt tcctgcgaat cctcactagc ttttttgtag
    38221 gaaggggcag caaaatgaca aacaaagtaa gagagctagg tgtatcttcg attgaggaaa
    38281 tgtttgattt agccacttat gcatttaatg gggcagatac acctgaaagg cgagaacgtt
    38341 ttcgtacact tgcggagaat tcttggaatt acggattttt tgatgaggag gatcggctaa
    38401 caagtcaagt catggcgacc ccttttccag tgaattttta cggacaagag tacctaatgg
    38461 ccggcattgg ctatgttgct tcttatccag aagcaagggg acaaggcggg atcaatcaga
    38521 tcatggaaaa gatccttgaa gattgccgtg atcgtaaagt aagcttatct tatctggcgc
    38581 cattctccta tcccttctat cggcgctatg gctatgaaca atcatttgat aaaatcagtt
    38641 atcaactaaa cagtcgtgat gtgccgttta tcaaaaaaaa atctggaaaa ataaagcgta
    38701 tggattttga agatgcaaaa gctgcaatca gaagaattta tgaacagatg ccggaaaacc
    38761 aacgagctgg tctgaagcgc gaagactggt ggtatacgta taaattcaag caaaaaggca
    38821 attaccagtt tgctttgcat tttgatgata atgaggaagc aacgggatat atcgtttatc
    38881 agcttgcaac gtcttccttt attattgcgg agtggggatt tttggatcat gatgcttttt
    38941 gcagccttgt tcgcttcgta agttctcaca atggtgcttt tgaaacattt gaatattcat
    39001 gcggctacgg cggtaatgat caaaattatc tattagaaaa tccatttgct tctgtaatga
    39061 tcacacctta tatgatggcg aggatcgtag atatttcttt gtttttggaa aattatccat
    39121 ttaaaaagag acaagctgca tttgccctac aaatagaaga agatcattat gcgaaatgga
    39181 atgaaggaat cgtggaagta acaatcgaaa atggaaaaaa tcatctctca aaagtagaac
    39241 aaacaaaact cccaatcgtt cgaggaagta tccaacatat cacgcagcta ttattagggt
    39301 atcgtaaagt ggaagagttg gtattccaag aaagaataca ggtgacaaaa gaatatgaag
    39361 aaacgttaag ctcaatcttg ccacagcaac agccaattct taatgactat ttttgataaa
    39421 aaacgggtga tgacaatatt tttgtcacca cccttttgtt tttcatttgg catttgaagg
    39481 aaaatgttaa agtaaatcct cttttttcgt aaatttgaat tttttgtttt cttttgtttt
    39541 agggttttct tttttgtggt cttggattgc ttctttcgta atcttttccc gatttttttt
    39601 agatgaatct aagcgttctg cgtatacttt ttcttttggc ttatcattca ttggaaagga
    39661 cctccctaca ttatttcatt ctacctctag tttatcatct gttaaggact agtggaaacg
    39721 ttttgcctaa cttataagct gattttttta gcagataagc ttgcaagtaa aaaacaaaca
    39781 agctacaatt gatttattga aattgttcct gtagctcagt aggatagagc aatcgcctcc
    39841 taagcgatag gtcgctggtt caattccagt caggaacgta taaataaccc ctgtatcctt
    39901 tgcggtacag gggtttgttt tgtatttgtg ccaaaaatgt gccaaactag ttatcatttt
    39961 tatataaact atcgaacaca gtattgattt tttctttatc ctgatcttca agctctcgaa
    40021 caatatgaag ataagtagac attgtagttt ctaaactgct atgtcctaaa cgtttcgata
    40081 cgctaagtat atttactcct tgataaagta aaatagatgc atgtgtatgc cttagtccat
    40141 gcaaagtaaa ttgcttttca atccctaatt cttttaattt tttgcgcaaa tatttgctga
    40201 cggcgtttga tgaaactaat ccatttttta agttgaaaaa aacaaaatta tgagggtttt
    40261 tgatttcaaa attctcgaat aattcttttt gattgatttt aaactttttt aagagatcaa
    40321 tcgtatgttt atcaatggaa attttcctat ttgaagtttc gttttttgtt tttccccatt
    40381 catttaattt ataattccat gttttattaa tagtgatgat ttgatcttcg aaatcgatat
    40441 cttcccatgt taatcctaga agttcagcaa atcgcattcc agtggcacca gcaactaaca
    40501 cgagcatagg agaagagtac tgcgcagaaa ggttttcttc tacgagtttc attaaagatt
    40561 taaattgatc ataatctaaa tatttatctt cttttggctt caatgaatct tttcctttga
    40621 ttactgcttt tctagttgga tcaaacggaa ttaatccttc ttctacggca tctttcaacg
    40681 acgctctaat atggttatta aacttaataa cggtagattt tacatggtct ttagcatact
    40741 tatttaaaaa gcgttgatat cccactctat ctaaatcaga aatcaatacc gctggcatat
    40801 atttctttat gttcattaac gtatcttcgt attttctata agtgatagga gatactgttc
    40861 cttctttata aagttgcatc caatcctcaa agtaatctga taataataga tttttgcgat
    40921 cccctttaag gcctttgttc aagttatatt ctaattcgtt ggcggcatct tttgcttctc
    40981 cttttgtctt aaatcctgat tttcttatct tcgtgtattt tccgtcatct tttttgtatg
    41041 aaatttcgta ttgccaacta tttccacgtt tgactaatct tgccataatt gaatcagctc
    41101 tctttctctg atacaatagg aactataaag aagcccattg tttgggtttt attatttttt
    41161 gcacatcctt tttgcttgcc ggcgcaagga tgtgctattt gtcgttttaa tggtataatt
    41221 ggatgtgtat tagatcatcc aatcagaggt gtttattatg attaaagtga tttttaaaag
    41281 aataactgaa cttccagagt ttagattatt tgttgattat tggtatgtct ggttttttat
    41341 tgttgcattg ctgataggtc tagatgtcat attagaaaga aaacttaagt aagagttgag
    41401 ttaataaatt gaattcctaa atgagatatt ttgtagccca tattttgttt gccgacatca
    41461 cctaatacta tggagctaat cgttttttct aacagaccaa aatcagataa tctatttaag
    41521 ctaccatcta ttagctcttg tgaatagcca gacatgctga tatttccagt gaaattttcg
    41581 tttccacgac tcattaagca tgctaacaat tgaatctcaa tcgatgttaa ttgattcagt
    41641 acaagaagat aatactcctc gttatcccat gaagcgttgt taattcgaag taaacaattc
    41701 ttataaagat ttttatacat atctatttta ttttgtgcct ttgatttttc tacctcgtca
    41761 tttatccctt cgaatattcc aatgagttgg tccttgttct ctaagttgaa aacatcttct
    41821 ggaatttgat cgcgaatgtt ttctaatgat tcgtttaaat ttttgtagaa tttctcgatg
    41881 cgtttgaaac gcttctcgtt tttagaccca aaataaagtg actgcacaac gccaccaata
    41941 taaggaattg ctccaatacc gccttcaact attaattcaa gatattcttt tttggttagt
    42001 ttttcattgc tattatccat agttacctcc tattttgtca tttcctttac aagcattgtg
    42061 actcctgatg gcactctttt gtataggttt tattattgtg cacaatctaa ctcttagtgg
    42121 ggcgtggttc atttattttt tacttacttt actattaatc atatcccatt gagcatagga
    42181 tttttctatg ttcgatcctc ttgaactaat ttctcctgta aaagttactt tatcgccctt
    42241 tgtaaaggta tcagcattgt ttaagtcctt cgcaaaaatt acatatgaaa ctttaggtgt
    42301 tgcagaaata tcattccaac ttttatcatc gtactctttg tctgctataa tggctattct
    42361 agtagtcatt gattcgataa cagttccttc aaaagtatat gttttaccac taatatattt
    42421 agtaaaagct gtattttgct cagtagctgg agtaatagaa taataactat ctaagaaagc
    42481 accccagtca tgattatttg tctctaaaaa ttcttcaaat tgagttaggc ttttattgct
    42541 gctgttagat gtagtagttt gagtatcaga tgatgagctt tcctgtttgt tattgtcatt
    42601 tgcctcgttt gatgaggaaa gcgagaaacc tacggtagta aaaataatcc cgataataag
    42661 gagaatcata ggtgttttct tatttgtttt tttgataaat cttacaatta acatgattaa
    42721 acctataata aataaaacaa taccagtaaa accaaatata ccgtccatta atagatcctc
    42781 tttctctttt gatattgaat attataaacc aagcaattct tttttcttaa aatcgaattc
    42841 ttcttgatta ataatccctt catctaacaa ctctttatac tttttaattt catctgcact
    42901 tgaaatttgt gtttctttgg aattattatc taatatagat tgttgcttct ctatatattt
    42961 ttttaaattt tccatttcat tccaatattt ttttgtaaac ataacggtgt tttcatcttt
    43021 cgtggccgct aatatacctc cgcgactttc gtttccgcct agcaaggtaa attgtatata
    43081 accattactc atacctggtt tttttaattg tacggctgat atatttttaa aggggatagt
    43141 tttttctcct ttaatacctt gattaactaa atttataaat ccttttctaa taattgaaat
    43201 agaatcatca gttactttaa tcaaggtttt tcctggagat tttattaaaa tctctttttc
    43261 cattttttct tcctcatttc tgtgatatga ttttttttgt agaagctcat atatgaggaa
    43321 agagcccgtg ttgcagcacg ggctttttta atgttttgct gaaatcggtt tttttaataa
    43381 ttcttgatgt attcatacat attgccttgc gtaagaatat tttttcttaa aatagcattg
    43441 gcagacagca taacaagtgt atctgagctt attctgaata gaataatact ccataaattt
    43501 ttcgagatta aactgagatt catcagtcag ttcgttctca atatagatat ttaataaaat
    43561 tagaatagct attttatctg cttctgtttc aaattttgag tgaaaagttg tagaagtatc
    43621 gtacaaaact gaaaattcaa aatgagaggc gctgaaatgt gcaagttcat gagataaatg
    43681 aaaggcttct gcagtttcac cgtatagatt ttcattcaaa aaaatgattc tgggttttgg
    43741 atagtagaaa ccaggctctt tcatctccat ataaactact ttcaaattgt attcgctcaa
    43801 catttctttc aatttcaaat acatacaaac catcactcca actattcatt ttcctctaaa
    43861 gctttagcaa ttgcaatcgc tttacgcatt gtctccttag atatttcttt tccatcaaaa
    43921 gaaaaaacag tatcgtcttc tgataaatcc acatgtttag gggtttctct ttcttctcta
    43981 cctagaaggt agtctacaga gacatcgaaa tagtcagcaa tccgacttaa ttcatctgaa
    44041 ttaggagtat tatttttcca ctttgctaga taaccgttag aatatccaaa attaatttct
    44101 aactgccgta tagatatctt tttcctcttc gccaagtctt ttattatttc ataggtattc
    44161 atcgataaaa caacctttct aaatgtttac aaaaaaagtt tagaaaaata cgcagaaata
    44221 atttgactaa ttctgagtaa tgagctatac tatatcttgt aaacagattt aacaactaaa
    44281 aagacaacaa aaaacactat tgatatgtaa atgcagaccg ccaagaaagc tttaaaatca
    44341 atgtttttat gtcttattta attatgctct tagtatagag tattactcag atactgtcaa
    44401 ttgaatttag aaaaaagttg ttaaatttgt ttacgaatat aaaagaaagg aatgagaaat
    44461 atgaacacac cgcaaatttt taatttcgaa caaaacgaag ttcggacaat tttagtaaat
    44521 gatgaaccat attttgtagg caaagacgtt gcgagtgttt tgggttattc aaacactaaa
    44581 gatgctttgt cgcggcatgt agatttggaa gataagatgg ggtcgcgaat cacgacctca
    44641 ggtcaatcaa gagagatgac aatcatcaac gaatctggtt tgtacagttt aatcttaaaa
    44701 tcaaaacttc cctctgccaa aaaatttaaa cgttgggtaa caagtgaagt gttgccagca
    44761 attagaaaac atggaggtta tctaactcca gaaaaagtag aagaagcttt gcttaatcca
    44821 gatacaatca ttcaattagc aactcaacta aaagaagaaa gaactggaag attaatcgca
    44881 gaacaaaaga ttgcagagta cgaacctaaa atctcctatt tagatagcat attatcttct
    44941 acagattcag taacaattag tcagattgca gcagattatg ggatgtctcc acaacagatg
    45001 aataaattac ttcataaact aggtattcag aaaaaagtcg gtaaccaatg gttattgtgc
    45061 aaaaaacaca tgaaccaagg atacacaaaa tctcatacaa ctgagatccc gaaagccgat
    45121 ggtggcacta aaattgtaat gaataccaaa tggacacaga aagggcgtct atttatctac
    45181 gaattactaa aaaaagaagg atattaccct caaatggatt tagaggaaat tggttagaaa
    45241 ggagttttag tatgactgac attgcagaaa tcactcaacg agatagagaa aaaatcaaag
    45301 aatatgtcga aagttcaaag ttcttaactt acaccatgct tgctgaaaga tttggaatta
    45361 gcaaaagcta cttatcttta attttaaacg gtaaaaagac ttctgcagaa gcaaacagaa
    45421 ttatagattc gattatcact atgtacgaat tgtaaaggga ggaacagcta atgcaatatc
    45481 tagaagcaaa aatcccaatt ccagaaggct atgtaattat ctcccaagtg gattatgagg
    45541 agttaaaaaa agctgatgat actggtagat ggatgacgtt gccagaagtg ctagaacgga
    45601 ttaacagaaa atatgattgg tttacttcta gagttttaaa gaacccaaga tatagaaata
    45661 ttatcgatat cgagaaaaac aaaaatggat ttgtctatta tccagttgaa ggaagagaca
    45721 catatctatt tttaagaagt aaaacacttg aatttttaga aacaaatttt tcggaaatct
    45781 taaggaggca agcggatggg aaaatttaat agagcgctag tgttcagcgc accgctaatc
    45841 atctacgctt taggactttg gggaagcagg caagcgttga taggaacgat tgtttacatg
    45901 gtttggattt ttatggggct tgatgaagct gaagctgagt acagagcgaa aaagccaacc
    45961 gagggggctg actaaaaatg aatagaaaag agaaactaga atgtatatta ctattactca
    46021 gtttaattct ttcactaatt tctctattgg gaagtttgta tttttgatat caacaatttt
    46081 gtggatttgg gttctattta gagtaaatat catttttgtt tggtgattaa ggagtttatt
    46141 aaaattaatt ttccctactt caaatgcaag gtaacaagat atagcacttt taggaggaat
    46201 atttagcggt acagcttcag agtatattct attatcatcg actgatcctc ctttagcaat
    46261 taatttctta aatggagtag ctgaccatct gcggtttaag ttagcggatg aaagttctaa
    46321 attaactaac atagctggtt ctgttgaata gttagaaatg attacttttg tataaatcat
    46381 atctgcagcg aagtaagaag cattaagttc aacttctagt tgagggcgca ttccttttat
    46441 ttttatccct gttaaaaacg tactcaatat aaaacttatt attgacatcc attgaaaaat
    46501 tgttaagtga aaaaaattca aaataaacac caccagtttt taactaaatt ataccaaaaa
    46561 ggagagaaga aataatgcaa gaattagtaa ttttgaaaaa taaagaagct gtgactacga
    46621 gcttacaagt ggcagaaagc ttcgagaaaa aacatcaaca tgttttaaga gatattgatg
    46681 cactaaaaaa agatgtgtcc aattttggac agatgtttgt agaaggtaat gaaccagatt
    46741 catatggcag aaatcgacga gttttcttca ttagtagaga tggatttttc ttgctggcta
    46801 tggggtttac aggaaagaaa gctatctact tcaaacaaaa atacattgaa gcattcaacg
    46861 aaatggaaga tgttattcgc aagaatactg ttcctcaaac aattgaagat atgatgatct
    46921 atcaattaga agaaatgaaa gatgttaaaa aagatgtttc catgcttaaa gatactatgc
    46981 gaattagcgg acaacaagag tttgaaatta agcaaaaagg aaatatgaaa gttatgggag
    47041 ttctaggggg aaaagaaagc cgagcttatg aagaaatcag caaaaaagta ttctcaaaat
    47101 tttggtctga atttaaacgt accttttcaa tcccaagata tggcgagtta cctcgtaaga
    47161 gattcgatga tgctgtttca tttattgaaa tgtggttgcc agaaactgcg atccgtatgg
    47221 aaattgatca actgaacaga caacagagac tttttggtga tgacaatgaa tagagctgaa
    47281 gcgctaagaa tagggacggc aattgctaat tgctggtgga aatactataa accaatcatc
    47341 ctaagccaac aacatattga caagcaaaaa gcatggcaac aaataaaaaa gtgactccgc
    47401 cggcaagcaa agagtcacaa agaaaacaca tcataaggag attttagcat atggaaaaag
    47461 aactttccac tctagatcaa tatttgattg atcctgattg gggcaagccg aaaattgagg
    47521 aaacaagtgg tcgaaaaatc agacgaaatc ttttgacgaa tgaagaacta gcttgggatc
    47581 aagatgattt aggcaaccat gtaactattt gggatcatgt ttatcttatc catctatcga
    47641 agcattcgaa taaacctgaa tatatttacg tcatcgaaga tggcttgatt gatgcgctag
    47701 aagagtacga cagagataac ttgattgata tctcttatta cggaccaggt aagaaataca
    47761 ttgctgaaat ggaggcagaa tttgatgagt gaaatcaaag ggacaacgaa ctttgaaaaa
    47821 ctttttagtc gtaagttaaa taaaattctc aagaaaaaag gaaattttga ttatttatct
    47881 tgggctcacg cgtgggagat tatgaaaaag aatgatccac aggcaacggt aactattaat
    47941 gagtacaaac actacagggt tgtttctgga actcatcaag actttcttgt tgaggaatat
    48001 aaaccttttc ttatggatga aactgggact tatgtatctg tctcagtaac ggttaaagga
    48061 cacacggaaa ccgaattatt tcctgtttta gattatcgaa accaaccagt tgttaaacca
    48121 aatgcaatgc aaatcaataa ctcattgaag cgatgctttg tgaaagcatt ggctctacac
    48181 ggactgggat tatatgtatt tcaaggggaa gatattccaa caccacctag aatcgataca
    48241 aagaaattaa acatgctaga gacgattcta gaagctttca atgagcagat gggtaaagat
    48301 atgaccaaaa ccttaatcga atatgttaat gagcagacag ataaattagg gctcttagct
    48361 gataacgttg aaactattga acagttaagc tatgagcaat gtgccttgat ggagcgagca
    48421 atagcagcta agagaaaaga attagataag aagtgatatg agtgtttaaa ccattaatcg
    48481 attcatattc agcggttctg aaaaagttca aaggaaaaga cataagcgca accatcaatg
    48541 aggaagtgaa cattgatcga ctaaagacga tgtatgacgg ctacgatggt gatcgagtca
    48601 ttgaaattcg ttttattgat cctagacgtt tcaccgtaca gcaacgaaac ttcatctatg
    48661 cgctgatagg cgatattttt atcgatacag gcatgccaac ggacttctgg aaggaattct
    48721 tctactttcg ttttgaaggt gtcacagggc gcaaaataag cctgaaagac gaatcgaata
    48781 caactgtgag tgatgccaat gtcttagcaa atatcatctt agatttcatc tttgaacatc
    48841 atattccttt caaagaaggc tatgagattt tacctgcgaa tcaagaatat tacttctaca
    48901 aatgcatcac aaaaagagtc tgctgcatct gtggcaaaac aggagctgac atcgatcact
    48961 ttgacaaagc gctaggaaga cgaaagcgca aagaagttga tcatgcagag tacacatttg
    49021 cagcactctg cagaatccat cacacagaga agcacaaaat aggtgtgatt aatttcaaaa
    49081 ataaatatca aatcaaaggg atcaaattaa accagaaaac aatcaaaaag ttaaatattg
    49141 gaggggaaaa atgacagaac atcgaagtta ttatgcgatt ataccagcca acgtaaggta
    49201 cgacaaaaga cttaaaccaa atactaagtt gttatacgga gagataacgg ccttgtgtaa
    49261 tgaaagaggc ttttgttggg caggcaatga gtactttgca gatttatatg gtgtgaataa
    49321 agagaccata tcgcgatggg taagtgattt gattaagttt ggatacttga atcgggaaat
    49381 catttacaaa gagggtacca atcaaataat caataggtac ctacgaatta atcaataccc
    49441 tattgacgaa aaacgcaata cccctattga cgaaaaagtc aaagataata atacatctat
    49501 taataataca tttaataata caaaagaata tataagagag ttaccgcctt cgaaaaaatc
    49561 gaaggctaag cccgtccgtc ataaatacgg agagtataaa aatgttcttt tgtcagatga
    49621 gcagatggag aaactcaaaa cagaattccc taatgattac caagagcgaa tcgaacgact
    49681 gtcagagtat tgtgaatcat ctggtaagac ttataaaaac tatttggcaa ctattcgaag
    49741 ttgggcaagg aaagaaaaaa gtgaacctaa gaacgcaagc agtggataca agcgcacagg
    49801 aagacgagag aagcttcctg aatgggcaat cgaccaagaa gcctatctca agaaaaaagc
    49861 gctagaacga gctaatagac aatcaaaagc accattctaa gaggtggaaa aatgaagatc
    49921 gattatctag aactaattaa tgaaatagcg aattataaaa agggcgagga attagacgtc
    49981 ctgagagacg tatatgatca actcgaagaa gctggaattg aaggaattaa gaatgatcgt
    50041 tcgagttgga gtaaactcag atactatttc gcactctata tcgatggaac gcaattaaga
    50101 aatttagcat ataccaaatt actattcatt gattgtgtta aaggcttgca aaaacatctt
    50161 aatgaacttg agcaggtgta aacaagatgg acctaaagac atttacagca cagatcgaat
    50221 taatgcatca agaagcttta agacaaagtg tgtcgtacga agacaagtgg ctcaacacat
    50281 ttcatggcgg acgtgagagc gcacttgatc aagtactcaa attactgaaa ggagaatgtc
    50341 gggatggata agaaagcggc aatgcagcga attatcgaat tgacttattc agaagattgg
    50401 caggaagata aaaaaatagt tgcagaagtc caaaagctcg gtaaatcaat gtggactgaa
    50461 aagcccaaac ggagaacgcc gagaaagatt gcaatctggc atggtgatcg aattctagta
    50521 acgggtaccg ctaaacagtt atctgaaatt actggtctga gcaaaaatat tatttgggat
    50581 agagctagga gcttatggat tgattcaaaa ggaagacagt ttaggtatgt ggaggagaaa
    50641 taatggacga actaatcgcg aaagtagagc agtgggcaaa agataaggga ttggatcaag
    50701 cggatttcag caagcaaatg ttaaaaacgg tcgaagaaat cggggaagtt gccgcttctc
    50761 tagctagaaa agatgaacat ggtttaagag acggaattgg cgatgtagta gtaaccttga
    50821 tcatcttggc aatgcaaaat gatatggatt tatacgagtg cttggatttt gcttatgacg
    50881 aaatcaaagg tcggactgga aagatggtca atggtgtttt cgttaagtcc agtgacctga
    50941 aataattcca ttaatggaag aaataactga ataggaggat agacatgatt gatgcaaaac
    51001 aagtgcaaaa acagaaagat ggaatgttga tgtttgaagc atatgttcta ccatttctta
    51061 atcaatttga agttttggaa tgctctgcca gcggagaaga attggagtat gttgtaattc
    51121 gtgaaaccaa agaaaacgtt cagaagctaa acgaatttct ttgcactatt aactgttggg
    51181 atatgatagc tccaggattt ttatgtccag ctatgggaga atttttggaa tattgtcgtc
    51241 ttgaagatgc aggcactttg gatttagctt atctggtata caactaccta aacatcaaca
    51301 cagatcattt gtggtttggc actgccgaaa gaaaatgggt agtccgctaa ccaccaatat
    51361 caatgaaaaa aggcggtttc ctgaaagtgg aattgccgcc attgctgtaa ggttctttac
    51421 gcgactcaag gtcacagaaa tataaatgca aatctctttt gaagtgatcc aaagctctcg
    51481 gaaaatggaa gttttttgtt tcaaagaata aatgagattt gcgtcaagaa cctgagagtt
    51541 atttccaaaa aagcttccaa agaaccgaat gagctaagga catcatgtgt aaacacataa
    51601 tatagctctc ctttcacggc taatcataac atgaaaaata ttcgatgtca gtaggaaaaa
    51661 aggtgaatta tgaaaagaat attaaattat cccggcagta acagattctg caattaaact
    51721 ccgaagctga tgtatcagta tcaactgtag aatattatga gcgtggagaa agtcaagcag
    51781 tcacaaatgt aaaaatcgat aacgtcaacg gtcttatctg tttagatgaa ggcgatagta
    51841 tgaatgaaat tgctgcagac catgaattat cagaaactgc tttaattgat caaatcgaat
    51901 tagctagaca atactttgtt ccatatgcag atacctggtc caagcataag aatgacatca
    51961 tttttccaga ggaacaatga gagcaactga tccagtaatt atccttgagg aagccaaatt
    52021 tatttggact cacgaagaga tagagcaagc acgcttgctc ttttctcaag gagttaagcc
    52081 gagcaaagta gctgaaataa tgggtcaaaa gattcttgat gtcggattgc ttttgctcca
    52141 tctagcagaa aaaatttgat ttgaggtgaa aatgatgatt caacttgcag gcatccaaac
    52201 agggaaaatt tatttttctg gagaaagcaa aagcgaagcc aaccaatggc tattgaaaac
    52261 ttacacgaac aataagaagc taaggaaaaa atatcctgat ttgttgctaa aggatgatca
    52321 gattatgccg gaaccgatga ttttgacccg taaggaggga agttgaaact aaaaaaccag
    52381 ccgtgtgggc tggagttgct atttcttttt aataatgagt ttttctaaat ttaattcatt
    52441 ctcacgagtt tgcgtccaat aatcagaata atattttaat tgtttaagag taggaatgtc
    52501 gtcttcggta aaattagaaa ataattctgg agaattatct ttttttaatt gttctaatcc
    52561 tgattcttta aaacgttgtt caacgagttt tactaaattg ttgatattca tgataaatca
    52621 cctttttaaa tttaatt
//
LOCUS       DAFLWC010000009        51564 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.009, whole genome shotgun sequence.
ACCESSION   DAFLWC010000009 DAFLWC010000000
VERSION     DAFLWC010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51564
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.009"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            108..554
                     /gene="nrdI"
                     /locus_tag="L1V17_000516"
     CDS             108..554
                     /gene="nrdI"
                     /locus_tag="L1V17_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBN1235306.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(619..2601)
                     /locus_tag="L1V17_000517"
     CDS             complement(619..2601)
                     /locus_tag="L1V17_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1235307.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(2615..3511)
                     /gene="murQ"
                     /locus_tag="L1V17_000518"
     CDS             complement(2615..3511)
                     /gene="murQ"
                     /locus_tag="L1V17_000518"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBN1235308.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(3514..4575)
                     /locus_tag="L1V17_000519"
     CDS             complement(3514..4575)
                     /locus_tag="L1V17_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBN1235309.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(4786..5352)
                     /locus_tag="L1V17_000520"
     CDS             complement(4786..5352)
                     /locus_tag="L1V17_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBN1235310.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(5380..6882)
                     /gene="eat(A)"
                     /locus_tag="L1V17_000521"
     CDS             complement(5380..6882)
                     /gene="eat(A)"
                     /locus_tag="L1V17_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBN1235311.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(7140..8261)
                     /locus_tag="L1V17_000522"
     CDS             complement(7140..8261)
                     /locus_tag="L1V17_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBN1235312.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            8387..9328
                     /locus_tag="L1V17_000523"
     CDS             8387..9328
                     /locus_tag="L1V17_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBN1235313.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(9478..10374)
                     /locus_tag="L1V17_000524"
     CDS             complement(9478..10374)
                     /locus_tag="L1V17_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBN1235314.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            10643..11983
                     /locus_tag="L1V17_000525"
     CDS             10643..11983
                     /locus_tag="L1V17_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1235315.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            12201..12644
                     /locus_tag="L1V17_000526"
     CDS             12201..12644
                     /locus_tag="L1V17_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBN1235316.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(13148..14566)
                     /gene="nhaC"
                     /locus_tag="L1V17_000527"
     CDS             complement(13148..14566)
                     /gene="nhaC"
                     /locus_tag="L1V17_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBN1235317.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(14969..16192)
                     /locus_tag="L1V17_000528"
     CDS             complement(14969..16192)
                     /locus_tag="L1V17_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBN1235318.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(16223..17062)
                     /locus_tag="L1V17_000529"
     CDS             complement(16223..17062)
                     /locus_tag="L1V17_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBN1235319.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(17079..17759)
                     /locus_tag="L1V17_000530"
     CDS             complement(17079..17759)
                     /locus_tag="L1V17_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1235320.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(17761..18834)
                     /locus_tag="L1V17_000531"
     CDS             complement(17761..18834)
                     /locus_tag="L1V17_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1235321.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(18890..19128)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(19171..19404)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(19481..20152)
                     /locus_tag="L1V17_000532"
     CDS             complement(19481..20152)
                     /locus_tag="L1V17_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBN1235322.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(20239..22917)
                     /gene="mgtA"
                     /locus_tag="L1V17_000533"
     CDS             complement(20239..22917)
                     /gene="mgtA"
                     /locus_tag="L1V17_000533"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBN1235323.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            23576..24013
                     /gene="ndk"
                     /locus_tag="L1V17_000534"
     CDS             23576..24013
                     /gene="ndk"
                     /locus_tag="L1V17_000534"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HBN1235324.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(24035..24901)
                     /locus_tag="L1V17_000535"
     CDS             complement(24035..24901)
                     /locus_tag="L1V17_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBN1235325.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLSHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(25061..27154)
                     /locus_tag="L1V17_000536"
     CDS             complement(25061..27154)
                     /locus_tag="L1V17_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBN1235326.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(27903..28526)
                     /locus_tag="L1V17_000537"
     CDS             complement(27903..28526)
                     /locus_tag="L1V17_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235327.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(28685..30082)
                     /locus_tag="L1V17_000538"
     CDS             complement(28685..30082)
                     /locus_tag="L1V17_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBN1235328.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(30114..31085)
                     /locus_tag="L1V17_000539"
     CDS             complement(30114..31085)
                     /locus_tag="L1V17_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1235329.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            31459..31884
                     /locus_tag="L1V17_000540"
     CDS             31459..31884
                     /locus_tag="L1V17_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235330.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            complement(32372..33073)
                     /locus_tag="L1V17_000541"
     CDS             complement(32372..33073)
                     /locus_tag="L1V17_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBN1235331.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(33089..33529)
                     /locus_tag="L1V17_000542"
     CDS             complement(33089..33529)
                     /locus_tag="L1V17_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBN1235332.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(33529..34104)
                     /locus_tag="L1V17_000543"
     CDS             complement(33529..34104)
                     /locus_tag="L1V17_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HBN1235333.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            complement(34952..35431)
                     /locus_tag="L1V17_000544"
                     /pseudo
     CDS             complement(34952..35431)
                     /locus_tag="L1V17_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(35590..36291)
                     /locus_tag="L1V17_000545"
     CDS             complement(35590..36291)
                     /locus_tag="L1V17_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1235334.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(36399..37808)
                     /locus_tag="L1V17_000546"
     CDS             complement(36399..37808)
                     /locus_tag="L1V17_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBN1235335.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            complement(37856..39721)
                     /locus_tag="L1V17_000547"
     CDS             complement(37856..39721)
                     /locus_tag="L1V17_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1235336.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(39842..40692)
                     /locus_tag="L1V17_000548"
                     /pseudo
     CDS             complement(39842..40692)
                     /locus_tag="L1V17_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            complement(41002..41715)
                     /locus_tag="L1V17_000549"
     CDS             complement(41002..41715)
                     /locus_tag="L1V17_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBN1235337.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            complement(41783..42109)
                     /locus_tag="L1V17_000550"
     CDS             complement(41783..42109)
                     /locus_tag="L1V17_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBN1235338.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            complement(42232..42459)
                     /locus_tag="L1V17_000551"
     CDS             complement(42232..42459)
                     /locus_tag="L1V17_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBN1235339.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            complement(42781..44034)
                     /locus_tag="L1V17_000552"
     CDS             complement(42781..44034)
                     /locus_tag="L1V17_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBN1235340.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            44095..44835
                     /locus_tag="L1V17_000553"
     CDS             44095..44835
                     /locus_tag="L1V17_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1235341.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            complement(44921..45679)
                     /locus_tag="L1V17_000554"
     CDS             complement(44921..45679)
                     /locus_tag="L1V17_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBN1235342.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(45676..46704)
                     /locus_tag="L1V17_000555"
                     /pseudo
     CDS             complement(45676..46704)
                     /locus_tag="L1V17_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
     gene            complement(46724..49891)
                     /locus_tag="L1V17_000556"
     CDS             complement(46724..49891)
                     /locus_tag="L1V17_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235343.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            complement(50115..50999)
                     /locus_tag="L1V17_000557"
     CDS             complement(50115..50999)
                     /locus_tag="L1V17_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBN1235344.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(51094..51531)
                     /locus_tag="L1V17_000558"
     CDS             complement(51094..51531)
                     /locus_tag="L1V17_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235345.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
BASE COUNT        14693 a        10907 c         8841 g        17123 t
ORIGIN      
        1 gcttttttct cattatacaa gcaaagcgcc tagtcccttt ccaaattaca ccaccaaaaa
       61 acttaaaaaa gatgctatac taaaaggaaa gaattggagg atgatccatg aacattttat
      121 atatatcgat ttcaggaaat acgcgtgcct ttgccaaaca tctagcagaa tatgctgaaa
      181 aaatgcatgc agaagatcct gtcaatcctg aagttacttt aaaagaaatc catgaaaata
      241 gtgattttac gaaagaaaca gaaccatttt ttactttcgt tcctacttat ttagacggcg
      301 gaaatggttt agataacggt gatacagaaa tcttgaccga aacgatgcgt gaatatctgg
      361 aacatgaaga caatcataaa ctttgtcttg gtgtagtcgg tagcggaaat aaaaacttca
      421 ataatcagta ttgtctaaca gccaaacaat atgcacaaac atttggcttt cctttcttgg
      481 cagattatga attacgggga acaccatctg atgtgacacg aatttatcag attttagcag
      541 aaaacaataa ataataaaaa agaagaagct gaaaaataga tttcagtttc ttctttcgtt
      601 tctattgttt ctatcatatt aagctttgac atccatcaca ggtgcttttg cttttgcttt
      661 acctgttttt tccaagacaa agttttttac acgatccata ttggttacca agacgatcat
      721 ggatgtttct ttgcctgctg ctttgatcgc ttctaagtca gcttctgcta caagcgtatc
      781 aggtgtcact tgctgccctt ctgttacttt cacatcaaat ggcgtaccgc ctaagtcaac
      841 tgtgttgatt cccatatgaa gcaagatttc taaaccattt ggcgttgtga tcccaatagc
      901 gtgtttcgtt gggaagacag agctgactac cccagtaact ggagaataga tatgtccgtt
      961 ttctggttct acaaagtagc cttcacccat catcttttgt gcaaaaactg gatcacttgc
     1021 tttatctaaa gaaacaactg ttccgtcagc aactgatgag aggatagtca cactttcagc
     1081 tgaagtttga ggtactactt tttcaggcac ttcatttact gtggctgttt cagtcgctaa
     1141 ttcttctttt tctaaacggt ctttaggaat accgaagaag aatgtagcaa cgaagccacc
     1201 agcataagct gccaataatc caaggatgta gcctaaccat ttaccgtcag agatcaatgg
     1261 gatcaaagcg gctcctgaag gtccaatagc gatagccccg acatttccga tcattccgat
     1321 cactgccccg ccgatacctc caccgataca agcagtaata aatgggcgtc ctagaggtaa
     1381 tgttactccg taaatcaatg gttcgccgat tcctaggatc ccgactggta aagctccttt
     1441 gatcatttct gttaattctt tatctttttt gcagcgaatc cataatgcca atgctgcacc
     1501 cacttgtcct gcaccagcca tcgcaagaat tggaagcaat agcgtacgac cagtttcatc
     1561 aatcatttgc acatggattg gagtcaaaat ttgatgcagt ccgaacataa ccatcggcaa
     1621 gaataatgtg cctagaacga agccggcaaa tgctccacca acgccaagta cccagttgat
     1681 cccaccgacc atgccatcag aaatgaaacc tgctaaaggc atgatgaaga aaatttcaat
     1741 cagaccgatg gcaatcaatg aaagagttgg tgtaacgatg atatctaccg catcaggtac
     1801 tactttatgc agttttttct caacgattga caatagccaa acagcgaaga tgacacctag
     1861 gatcccacct tgtccagctg caagagcttc accagtaaat aagtttttca gtggtgcttc
     1921 cggattcatc cctgtcagca tcacaacggc cccgataact ccaccaagag ttggtgttgc
     1981 accaaaaact tgtgcagcat tgatacctgt atagataact aggtagctaa acatcccgtt
     2041 tttcaagatg ttcatcacat cgatatattg ttgccatgtt gctgcatcaa gtgttccggc
     2101 tgtgactaag tttgctaaaa ctgcggcaat ccctgccacg atcccagtac cgacaaatgc
     2161 aggaatcatt ggcacaaaga tattagaaat gtcttttaat accgatttga ttttagatgg
     2221 tttttgtttc gatttttgtg ccgctttcat ttcttgtgcc cgttcgttta cacggtcttt
     2281 tccagatgct gatgaatttg ctgtagctgt acttacagaa gaaagttttt ctcctaattt
     2341 cacgcctgcc aaatcaacca tttgctgtgc tactttgttc actttcccag gtccgatgat
     2401 gacttgaagc tgttcatctt ctactacacc aagcactcct ggaatcgctt ttaattcaga
     2461 gacatttaca agatcatcat tgatgatctt catacgcaca cgagtcatgc agtggacaat
     2521 gctttctaca ttgcccatgc cgcctgcccc tttataaatt tgttttgcca gttcttccaa
     2581 agtcagttcg ttttttgcca tggtcttttc cccctcataa ggtccctttt acaaatccgt
     2641 ttgcttcagc taattttgct tgagcttcct ctttatcact atttgtcaaa atcatgacga
     2701 tagccagctt aacattttga tctgcttctt caaagtactt ttcagctgtt tcgtaatcag
     2761 cttctgtcgc ttgcatgatg attcgttttg agcgttcgat tagtttttca tttgttggtt
     2821 tgacatcgac catcaagtta ttgaatactt tacctatacc aatcatactg atagtagaaa
     2881 tcatattcaa gataagtttt tgtgctgttc ctgacttcaa tcgagtagag cctgtcaaaa
     2941 attctggacc tgcatcgact tcgattggga aatccgcgtg tttactgatt tcggcttgtt
     3001 tattgcaaga aatcgttcct gtgacagcac cgatcgattt tgcgtaatct aatccaccga
     3061 tcacatatgg tgtacgaccg ctagctgcga taccaataac tatatcattt tttgtcaaat
     3121 tcagcttgat tagatcttct tgccctagct cataagaatc ttcggcccct tcgacagcta
     3181 cagtcattgc ttcttctcca ccagcaatta gacctatgac catttccggt tctacaccga
     3241 atgtcggtac gcattcagca gcatctaaca cacctagtct tccacttgtt ccggctccca
     3301 tataaatcag acgtccacct tttttaaagg actcaatcgt gttagcaatc actggttcga
     3361 tacttgtcag ttctttttca accgcagcgg ccactttctg atcttctttg ttcattagtt
     3421 gaacggcttg agaaatactc atctcatcta atccaaaagt ttcttggttt ctgcgttccg
     3481 ttgttaggtt ctctaaattg attttgctca tttttatctt ccttcttttc ttataaattg
     3541 atagttcata ccagctttga tttggttgat caatggtagc tcttctttga taactttagc
     3601 tactacattc actttttcat ccgctggcaa atcatatttg gttaattgga tctcacccat
     3661 atagcgcaaa tacttttcgt tatctaaagt aatagaccct ttcatacgcg tagctgtatt
     3721 tcttgctggg ataggcggaa tctctcgaaa acgtgcatct acgcttcgta tgacatctct
     3781 tgcatcgtct tgccgattcg tatgcttccc taatatatat tcgtaaaatt cttcatctac
     3841 aggttccgta tggagcaaga ctgtctgttc tttttggaaa gaagcaaatt gctcctgaac
     3901 gttttctgac agacctgcat ctccgatgta aacaatatcc gtgttacttg ctaatagatc
     3961 tagagcgcct gcaagaggat ggatccctcg atgttcttcc aaagttggca atccttgata
     4021 tagtgggcct ctcaactctg tatctcctgg tacaaaacct tggacaagga gaccttgaat
     4081 tttgagccat tgattttttt tctgatacca ttctttgtcc agccctgttt cgggacgtgg
     4141 ataataatta tgccaagctt caatctgtga gaaatcagct tctgcttctt tcaattcatc
     4201 gatatcttta ggcgtgatcg tgctagcatt caaactgatt ttcaattgat gtgaccagtc
     4261 ggcaatctgc tgattggaaa tatgataatc cattcttaaa cctgttacac caattgcttt
     4321 caaaggcgtt agatcttcta atgaaaaacc cgctcgttcc aatgcctctc ctgaaatatc
     4381 gaccatcaat tctagtttat tctttttcgc ttcgcttcct agttcgatca atcgcttttg
     4441 atatgccgaa acatcatctt ctggtatatg catggaagtg aaaataccga caaagccatt
     4501 ggatgccatt tggcggatat actgtttctt ctcttctgac aaagaatcgt tcataaatat
     4561 tgaaaagcca aacatattat ccctcttttt ctgtatccgt cttcatttct atgactagag
     4621 tatatatcta aagaaacaaa atttcaatac ttttattaaa ataattaaat ttcatttcta
     4681 aaggttgagt ttatattatc aaaagaattg tcataaccta aaaaaggcac tgctaagcaa
     4741 aagcagtgcc ttgaaatatt ttatttaaat aacacaaaaa cataattact cataagaaac
     4801 caattctgta ttatctacca tgaatgtaaa gaacccctca ttaggcatcg gatgaaaata
     4861 agcattgatc actcttatca aggcattatg gcaaactaac agatagacat tttcttcgtc
     4921 ttcgatgcat tctttcaata aaggaacgat ccgtgcatac acatctaaga ctgactcccc
     4981 atttgggaat cgtacagcga acgctaaacg tgctttttga aagttctcat ctttgcttgg
     5041 cagtccatca taatccccaa aatccatttc taccaatcgt tcatcaacgg tcagcggcaa
     5101 gctgagacga tcagcaactg cttgtgctgt atctcttgct cgttgaagag gggaatggat
     5161 gattttcgtg attggaacag gcaaatctac taccttttct gctagtttct gtgcctgcat
     5221 ctgtcctttt tcagtcagcg gcacatctgc ccgtccgcaa actaatcctt gtgcgttcca
     5281 agttgtttct ccgtgtctcg ttacataaag catgtgattc tctccttcgt tggcaaagtt
     5341 ccccttaacc ataccttgtt gttcttgaga ttacaagggt tagattctct caagagaaat
     5401 aatctcagta gatactttat ccaggaaggt ttgatcatgt tccactagta acatggcagg
     5461 tttcacgttc aagatcagtt gttctaattg ttcttgattg aagacatcca aataattcaa
     5521 tggttcatcc catgtatata gttcagctgg ctgtgataaa gatttagcca attccacttt
     5581 tttccgttgg cccatactca tctgctcgat cttgttatga aaaacatctc tttccatccc
     5641 aagctttcgg aggttgttca aaaatgcttg gtagtctact tggtttttct ctgcaaattc
     5701 cgccaacgtt cctcgattgt cttcataatt ttggcttgca taactaatgc tcagatgttt
     5761 tggctggtat ttttctccta taaccttgcc gttgaatgcc cccagaagat aatggataat
     5821 ggatgacttt cctgcaccgt taggacctga aatcgccacc cgctgatgag gctcgattgt
     5881 aaaatgaatt ggctcgaata acagattttc ataccctaat tgaagatctt ctacgcttaa
     5941 aagtcgctta tggtgagacg cttggctatt catcgtcaaa gaatcgatat attcgatatc
     6001 ttttaatagt ttttctttct cgctgatctg ggtctccatc cgattcacga ttgctttgga
     6061 tcgtttcatc gtccgtgcag catcagcacc cactgctcct ttattcactc gtctagattc
     6121 agtatcgatg aatccgactt gtttctttgt tttatctcct tctcgggaac gagaccattc
     6181 ggctttttca gctgctgttt tctttagcct actgacttct tttttcaatt tttcattttg
     6241 agccatttca aattcatcac gaagtttttt ctgttcttca tagatagaga aattcccttg
     6301 ataaagttcc agttgacttt tttcgattgc taaaacatgg tccactactt catcgataaa
     6361 tccccggtca tggctgacca cgatgaagcc ttgttttttc tttttcaaat aagccgctac
     6421 ttgttttcta ccagagatat ccaaatgatt cgttggttca tcgattaacg ggaaatgagt
     6481 gtcatccaca aataaaagtg ccagtaggac ttttgtcttc tctccccccg atagtgtgct
     6541 gaattctctc cataagattt caggatctgt ttgcatcaat tggagctctc tttcgatttc
     6601 ccatatctca aaatccgtaa tatcatttaa cacgtaatag gttaaacgtt ctttatcttt
     6661 tgtctgttgc gggaaatagg caaattcttg ctgatggatt acttgccctt gataaggtag
     6721 tttgttttgt agaatattca gtaaagttgt ctttcctcga ccgtttcgtc cgataagtcc
     6781 tagtttccat tgtgtgtcaa aatttagatt tgcttgttca aataataatg tgccttggct
     6841 gtcgtagccg aatgtcagat tttttatttc gattttagac attttccatc acctcgtaaa
     6901 aaaagaccag tcctattttc agaactggct aaagaggatg caagggttgg atacacacaa
     6961 aaagacccat acatcgaaaa aaccaagcca atcccgaaaa tctgcacact gcttccttgt
     7021 ctccacaagg tacagtctga atgcagcttt catcaatcga cttaattttt caatgcacgg
     7081 atccctcact ttgtcctata tttgaaatta cgatagcata aagaaaatga ttttgtcaac
     7141 tacttcggga ggatggtgaa aaatctgcta agtgtctgtc ctaagatttt tgttttttct
     7201 aatgtttgcc tgtgttccat tgcttcttct aaacctattg gacccaaatg aatacttaag
     7261 acaattggga gaaaatcaga aagtccttct agctcttggt ctctacttcc gcaaatagcg
     7321 attattggtt ttcgatattt ttttgcaagc actgctacac cgtatggaac ttttccgtgg
     7381 atcgtttgct gatcgatccg cccttctcct gtaatgatga catctgcttg ttcgatcttt
     7441 ttttccaatc cagtgatttg gctgactaaa tcgaaaccag aaaccatctt cgctcccaac
     7501 aaaaaaaggg ctccaccaat accgcctgct gctccacttc ctggaatatc atctaaatcc
     7561 acctcccaga aatcttttat ttgctgagca atctttcctg cttgtttatc taagaaagct
     7621 agcgtcgtat ctattcctcc tttttgtctt ccaaattgcc aagcagctcc ttgttgacct
     7681 gtatatggat tggtaacatc tgcagcgata atcaatttta ctttagaaac aagaacgttt
     7741 cttcgatcaa aatgaagttt tttagtagat aataaaggat ttccttctgt gtacccttct
     7801 aaagaagcac ccaaggattg gagtaatcct agaccaccat cgctacaccc gcttcctcct
     7861 aaagtgacaa taatttgttc tacttcttga agcagtgcat ctttaataag ttctcctaag
     7921 gcataactgg aagcaagtcg gatagtttga tccgttggtt tatcaagtag atctaacccc
     7981 aatgcttgtg cagattcgat gactgcggtg ttttttcctt gccaagttgt caataaatag
     8041 ctgatttttc gctgacggaa taagagatcc atcccatcaa tggtacgcca tgttcccctg
     8101 agcgcgtaat agattgcttc tgcagtattt tctccgccat ctgcaatcgg cacattgatt
     8161 tttcttcctt tacgatcttc ccagccattt agaactgcct gatttagttc aaatgaagaa
     8221 gcacttcctt taaatgaatc aattgccgcc aaaatatcca tctgtatccc tcactttctt
     8281 cttaagtaag acactttttt tcattttttt caaacaaaac aatgctattt tcttccattt
     8341 ttctatatac taaaagggaa ctcattgaat aaaggagaga aaaaacatga aaatcgcaat
     8401 agctggggcc ggagcaatgg gcagccgaat cggattgatg ctacatcaaa gcggaaatga
     8461 ggtcctcttg atcgatcgtt ggcctgctca cattgaagcc attcgtacaa atgggttgat
     8521 tgctgacttt aacggtaaag aagtggtcgc aaaactgcca atctattcac cagaagaaat
     8581 catcgaaagc aacgaacacg tggacttgat cgtagcatta acaaaagcca atcaattaga
     8641 tgatatgttt tgttcgatcc aatccattat tactgacaat acttatgttt tgtgtttact
     8701 aaatggatta ggtcatgaag atgtactgga aaaatatgtg ccaaagaaaa atatcttatt
     8761 tgggatcacg atgtggacag ctggtctagc tggtcccgga aaagtcacat tgttaggtga
     8821 tggagaaatc gaactagaga acttggaacc agaaggcgaa gcatttacaa aaaaagttgt
     8881 agaagtcttt caagaagcaa atttaaatcc gatctatagc cataacgttc gttattccat
     8941 ttggcgaaaa gcttgtgtaa atggaacatt gaatggttta tgcacgattt tggattgtaa
     9001 tattgctgaa ctaggcgcgc aaaaagcggc agagagcatg gttcgaacaa tcgtatctga
     9061 atttgcttct atcgcagcaa aagaaggaat catactagat caagaagaag tgtaccaaca
     9121 tattgcttct acttatgatc ctgacaacat cgggttgcat tacccatcta tgtaccaaga
     9181 cctgatcaaa aaccatcgtt tgactgaaat cgactacatc aatggtgcca tttggcgaaa
     9241 aggacaaaaa tatgatattg ctacaccata ttgtgccttt ttgacccaat tagtccatgc
     9301 aaaagaagga atccttggcg cagaataaaa ggctctctga tgagaatcag ctgaatcagc
     9361 agctggttct ctttttttaa gcccaataaa agatcaaaaa gaaaacacaa ctctcatgat
     9421 gccataagaa ttgtgcttgt ttgtttcagt acataatctc ttcaaaatgt aggtttttta
     9481 tttgttttca acagaggaga ggtcatattc gtattgctca taaatagtgg aatcgttagt
     9541 gataaatcgt tttgcccaat tttctgcatc ataaaattcc aatagctctg ataggattgg
     9601 cttaaatggt gtatgcagaa attccggtaa ttcatctaaa tcacgttctc gaagcaaaaa
     9661 aatattttca ggacgataaa aatgataatg agcaatcgct tgattatccg tcactagttt
     9721 cttttgaaaa tacatggatt caaatgtccg caaagtcact ccttgctgac cctcccgcaa
     9781 cagttccaga atcccgcgcg attcccctgt ttttttcagg tactcttcat aagtaagata
     9841 tccaggttgt tcattccctc gatgtggaag aatgaaatag ttggtcgtaa catctctttt
     9901 tataaattcc tgcttatagc tttctgctcg ttcttttctc ccattattcg ttgcaccaaa
     9961 aaatagatcc gtctttggtt cgctagaaga aaaattcata tgtttcgaat aaaatgaact
    10021 attatgtttc agcccaagtt cttttgcttc caaaaaatca aaatgataaa tctcatcgat
    10081 tgccggttca tcttgtgcct gcttcagcat cgcctcgtgt tctgctttga agtgattcca
    10141 aaaaaataac acaatttttg cattggtaaa tgggcgcacg cgtcgagcca tctccatatc
    10201 aaatccataa tctaaaaaaa cgatcagctg ataatttgcc aactgttgtc tagctgattt
    10261 aatgaattcc gactgtagta aatcttttcc ggaccaaaca tctaaagagc ggatggaagg
    10321 caaaaaataa agtgatttat tttttgcaac tagcagtacg tcatttttgt tcatcttttc
    10381 cgcctcactt tctctgtcac tttttcctat gatagcctgt ttaaatagta aaaagccagt
    10441 aaaacgtttc ctatatttgt atgaaaattt aacatttgta tgaaaatatg atgaaataaa
    10501 tcattcttct attaaaattc gcctaaaagt tttctgaata gttgtaattg tctgaaaatt
    10561 tgttatcatt agtcattgtt aaatattgct atttattctt aatataaatt ttgattgtga
    10621 atttaaaaga aagaggtcat ttatggaaga taaaaaattg aaaaaacaac ttagctccag
    10681 acatatcacc atgttagctt taggtggagc aatcggtgca ggtctattta aaggaagtgg
    10741 cgaagcgatt gggatcgccg gcccttctgt attgattgct tttttgattg gtgggctgat
    10801 tttatatatc gtgatgaaag gtctgggaaa aatcgtttta agcggtggcg acacgcatca
    10861 cggattatct ggtttgatac gcccttatct aggtgctcat tctgctgatt ttactgattg
    10921 ggtctactgg tctatgtgga ttatcaatat catcgctgaa gctgttgcag ctgcttcctt
    10981 tttgcagttg tggttcccgc acattccagc ctgggtattt gtttttatgt tggctgtttt
    11041 aactacgatc atcaatcttt attcggtacg gttattcgca gaaacagaat attggctggc
    11101 ttttgctaaa atcagtgtca ttatcttact gatcattttt gctacttatc ttgtcggtca
    11161 gcaaatgttg ggcacaggcg ttttccctac ccttcagcaa ttgactgacc atggtgggtt
    11221 tactcctcat ggtatgaagg gaatcatcag ttctttgctt gtagttatct attcttacgg
    11281 cggttctgaa ctgattgcta tcacggtaag cgaagcagat gatcctaaac gtgcgattcc
    11341 taaagcaatc aaaggtgtca tgggaagaat catttccttt tacatcattc ctttgttttt
    11401 gcttttgatt ctttttcctt ggaatacttt agcaggcacg aatgtcagtc cttttgtgat
    11461 ggtatttgaa aaaatgaata tcccatttgc agcggatatc gtcaattttg tgattgtcct
    11521 tgctttgttc tcatctatca attcgggtgt gtatgcatct tcaagaattt tgttcttccg
    11581 tttgaaggat cgaaaaggtt cctctagaaa actagctgtt ttaaacaagc atcaagtacc
    11641 gcaacgtgct gttttatttt gtaccagtgt tctttatctt ggtgtagctc tttcttattt
    11701 tgtcggtgac aaattatttg gctatctggc aggttccctt tcgtatacag tattattgat
    11761 ctggatcatt atcagtgcgg catcctttgt actggcacta agaaaaggaa cattatggga
    11821 taaaggaatc agcttttttg cattagctgt cttaggattg attttccttg gtatcctgtt
    11881 cacgaactcc attggggtaa ctgtattgac tggcctgctt tacctgttca tttatttcag
    11941 ttatcaaaaa aagaatgatg cgttcgtatt gacgaatgaa tgaaatcgat agaaaatttt
    12001 attttattta tgtggaatag atggagctat tgaagaaagg agttgtgaca aaagtcttgt
    12061 tgcaactcct ttttccgaat aaacagtctc atgacctctt ggtaaacggt gttcaaaaac
    12121 cctctgtgca aaataattga ttgttctcca tgctcatgac atgatagaag aaaggaatga
    12181 aaaaaaggag tttgttttaa atgaaaaagt attggaagtt tttgttgatg atcggtgttt
    12241 caacggtagt tatgtttggt atgatgtact tgaatgtcta tgcgctcgat catatcttct
    12301 tcagtcgtac acgagtattc atggcgttga tgatgggtgc agtcatggca gtcatcatgc
    12361 tgttgttcat gtggaaaatg tatgaaaaca aaaagataaa tgttatgatc ttagccgcta
    12421 gtcttcttgt ttttgccggt tccttgttta tggtacgaag ccaaactact gtcaacgaca
    12481 cagcttggat gaaggccatg attcctcatc attctatcgc tatcctggca agtaaacgag
    12541 ctgatttaaa agatcctgaa gtaaaaaaat tagcggaaga aatcattcag gcacaagaag
    12601 aagagatcga caaaatgaaa aaaatgatca aagaaatgga atgaccatta tccgtccaaa
    12661 taaaaaaaga ggatgttcca gaagttatca gcttcaagaa ataagaagaa gctacttctg
    12721 gaacgccgtg aataaggggt tgtgaaaaag ctgccctgca tcaagtaata agaacagcca
    12781 aacaaaaata gcttctccta tttttcgttt ggttaggctt attaccgcag atgcaagctt
    12841 ttgaacaccg tttattaaga ggttgtaaaa tcagcgttct gacctgagta ttagagagac
    12901 aaatggaaaa atagttcctc atattttgcc attttttgag ctaataccga gggtcagctg
    12961 attgaacacc gtttatcgag aggttgtgaa aaagtcgctt agtttcgcgt attaagaaaa
    13021 attttgtgaa atggctttcc acatttttgt ataaatttgg cttaataccg agaaactggc
    13081 ttttgaatac cgtttattcg taaaagggat tgtgacaaaa gtcttgtcac aatccctttt
    13141 tatgttttta ttgttctaat tgcgctgtct tgcttactgc ttcttgcggt ttcacaaatt
    13201 tttttgagat tccccaacct gtgaaggcac tgaccatcga aaacacagga gaaagcaaac
    13261 tgaaaaatac gaatggcaag taagtgagtg taggaatacc aaatgtactt gctacgaaac
    13321 ttccggcaat tccccaaggc actaagtagt tgattactgt tccaccatct tctagcgttc
    13381 tacctaatac agttggatca aatcctgctt tttcataagt ttctttaaat gcattaccag
    13441 gcagaataac agataggaat tgttcaccaa taaaaatatt tactccgata cttgtcatca
    13501 atgttgtaaa aatcaaattt ggtgtgttcg tcatctttct tgatactcgt tccatcacgg
    13561 ttgagatcaa gccaaattcg atcaacaatc cacctaatga caaagttaga ataatcaatg
    13621 acacagtagg catcatactt tcgattcctc cgcggctaag cagtgaatcg atttgttggt
    13681 ttccagtatt tgaaacaaac cctgattcga tgaccccagc caacttcgtt aaggaagttt
    13741 gtgggttttg aataaaaatc attcctactg ctacagcgat attcaacaaa atcgttaaaa
    13801 ttgccggcac ctttttccat gcacacagta acattaaaaa taaaggaatc agtgaccaga
    13861 ttgaaatagt aaagtttgct tctagaacat cagtcacttc acgaatagat gaaagacttg
    13921 cggctttact tgtgtgtcct aaaatcatga ataaaaagaa agaaacaaca aatgccggga
    13981 cagttgacca catcatatgc ttgatgtgtt tgaacaaatc ggcatcaaca atagctgctg
    14041 ctagatttgt tgattcggat aatggagaca tcttatctcc aaaaacggca cctgaaacaa
    14101 tagctccaac aaccagcgct ggatttaagc ctagtgttgt cccaataccg aaaaatgcaa
    14161 tcccaatcgt tgacataaca gtaaaggcac tccctacagc gctacctacg attgcacaca
    14221 caacaaatac agaagggaca aaccactgga cactgatcaa tttgaaccca atgaccatta
    14281 gagttggaat gatccctgct tgtatccata cagcaatcaa tgaaccgact aaaataaaaa
    14341 taaagattgg gatgattcct ggtttgatgc cattgatgat tccttcgtgc agccaatctg
    14401 tcgggtatct ttttatcact gcatacaaca tgaccattcc gatcgctgct aagatcgtga
    14461 tattaggtga gacctttaat ccgacaacgc caatcgcaat gcctaaaaca ataaccatta
    14521 atacaagtgt tgcttctaaa aaacttggtg ttcctttttt tcccatgata atctctcctt
    14581 ttttagttgt tcttatgttc taaaaaagtt aagatatcgg attactccgc cgcaattcat
    14641 ccgcgattcc tcctttataa aaataaaaag acctgtttta aactaaggac gaatgactcc
    14701 gcggtaccac cttaattaaa aacagatctg tttttcactt tcaaactttt attcaaatgt
    14761 atggactttc catgtaattc gtcaattagg cttgatcggt tcacagcgac caccgacttt
    14821 ctgaacaaaa cacctaaccg ctactgcgtg aaaagttgac ttgtacgaag tttaccttcc
    14881 ataagatcat ttgtcaatga aaaagaaaat attttttcat ttttctgaaa attattttta
    14941 taactttcac acacaagttt attttttact agaaagtagc gccctcttgt ttttttcttg
    15001 ctactatttc ttgatgttct tgcttgattc tttctaatag ctttggctct ttcaacagat
    15061 caagagctgt attggcgagt agttctgctg caatcgcaat agaagcaagg cctttgtcac
    15121 ttttagcagc agctttgaat tcttctgtgt gtccggcaat atatgtctca gagattgcta
    15181 ccgtaggctg gattgttggt atgacttggc tgacatttcc tacatcagaa gaaccgagac
    15241 ttgttctttg ttccgtttct atttcttcat ctggaacacc tgcttctttt gcatgctgga
    15301 agaataagtc atcaaaagaa ggagtaacga tgacatcatc aactgcattt tggaacaatc
    15361 caaactcaaa agtcgtgccc gtacttatcg cagcacctcg tacgatattt tccacttttt
    15421 catatacttt atctaatgtt tgccgatttc ctgcacgtaa atagaaacgt ccagcagcgt
    15481 aatctggaat gacgttggca gctactcctc cgtctgtaat gatcccatgg atattgacat
    15541 cttttggcaa ttgcaagcgt agagcgttga ttccattaaa cacttggatc aatgcttcca
    15601 aagcatttac tcctttttca ggtgctgctg ctgcatggga agcgacaccg taaaatttga
    15661 tgtcgactgg atcattcgct aaagattctg tcgttttccc ataacgaaaa gctggatgga
    15721 cgcataacgc tacatcgaca tcctcaaaaa aaccttctcg aacaaagctg cctttagctg
    15781 atccgttctc gcccccttct tcccctgggg tgccatatac acggatttct ccaccagttt
    15841 catcaatgaa ttgcttcact atgctggcgg ctaatacgga gtaagtacca aacaaattat
    15901 gcccgcatgc atgaccaata cctggtaaag catcgaattc tgccaaaaag gcaattgtgg
    15961 gaccgggttt attggaaata taacgtgcat caaaggctgt tcggtgtcca gctacttctt
    16021 tttctaccca aaacctttct ttttctaatt gtttaatcaa cgctgctgag gaataaaact
    16081 catagttact tacttcagga tgttcgtgga tatctagagc aagtgcttga tattctggta
    16141 aacgatattg gattagatcc ttcaattggt ttgttgagat tgttgttgtc ataaaaaatt
    16201 cctcctatgc tagtcatttt tcttattttc tcccgaatgt ttcccatgca ggcacgcttg
    16261 atccttttga tgttttctcg attactttga ctgtgtcttc tgtttgataa gcgtctacta
    16321 ttttttgata cgttttattg ttttcatctt cttttcttgc aacgatgata ttcacataag
    16381 gacgtgcatg gtcatccact ggttctaaga agatggcatc agaagcagga ttaaatccag
    16441 catctacagc tacaccgcta ttgatcactg aaatgtctac atctgacaaa gcacgtgctg
    16501 tttgggaagc atctaattca gaaatgtcta gattttttct attctcggta atatcagaaa
    16561 cagtgggcgc ttgtcctttt gccttatcca ctttgatcaa tccagcagtt tgcaataaca
    16621 gaagagctct gccgccattt gtaacatcat tagggattgc tacttttgct ccgtctttga
    16681 tatcagctac atccttcaaa gtgttagaat aaattcccag cggtgcattg acagtatttc
    16741 cgatcgatac taaatcagtt ccgtgttctt tattgtaatt gtctaaaaag aattgatgtt
    16801 ggaaagaatt caaatcaatc gatccatctg ctaaagccac atttggttga ttgtaatctg
    16861 taaatttcac gtattccaaa ttaatgttct cctttttcaa acggtctttc acgttgtccc
    16921 atacatctgt atcttctcca ataatcccta gttttacgat agtttctttt ttgtcagttg
    16981 tatctgcttt tccttggcta caccctgcca accaaataat tgctacaaat gtaatgacta
    17041 caaaacgaat aatttttttc attttttctc ctccactttc aatgtgtaat ttttttaatc
    17101 agttgattac tgataaattg acttaaaaaa actaagatta gaatcaataa tgtagccaca
    17161 atcgttacat ctgtttggaa tcgattatac cctctcgata tagcaagatt ccctaatccg
    17221 cctgcaccta ctgctccagc catggtagtc agtccgatca cgttgatgat agtcaacgcc
    17281 gagacccgaa tgataccagg caaaccttct aacaaataca cacgtaaaat gataccgatt
    17341 ggactggttc ccatcgcttc tgccgcttcg atcaccccag gatcaacttc tagcagtgcg
    17401 ttctcgattt gacgagcaaa aaacggaaca actccaaaaa tcaatggcac taaagctgct
    17461 ttcgcaccaa tcgtcgttcc aactaagaaa cgagtagtca atgctaaaag agaaagcaag
    17521 ataatgaaag ggatggaacg aatgatattg atcagcttat caagtatttc aaatagcaga
    17581 cggttagcta gtaatccatt agggcgtgtc actactaacg tcacacctaa gatgattcca
    17641 atcatcccgc caatgaatgc tgtccaaaaa gacatatata gtgtttgctt cgtcgcttcg
    17701 acaaattcat ccggaatcaa ataaacattg ggcaaatatg ttttaaagaa atcagtcatt
    17761 ttatcttcct ccttcgatca ctttgatacg actatctaaa tcgttttttt gtaaaatatt
    17821 tatttttaca ccagatttga tcaaataatc caatgctttt ttccgctgtt tggtttctcc
    17881 agctaaagta acgatcaaac tccctaacgg cgtttcttgt aataactcta cattgccata
    17941 taaaatattc gctgttactt gatatttgct gtacagatga gcgattagag gttcgttcgt
    18001 ctgatttcca atataactta attccaccag ccatttattg gcgatctgat cggcaaaagc
    18061 agaatgggca atgatcgttt ctaatgcttg gtcaagatga gtagctgttc gaataaaatc
    18121 tttggtcaat tcttcttcag gattgctgaa gatctggatg ctgctacctt tttcaacgat
    18181 tcttccatct tccataaccg ctaccttgtt gcagatttct ttgacaactt gcatctcatg
    18241 agtgatcagg acgattgtta aacctaactg gcgattcaat ttttttaaca atgcaaggat
    18301 ctgaagggtc gttttcggat caagtgcact ggttgcttca tcacataata ataccttagg
    18361 ttcattcgcc aaagctcgtg cgattgctac tcgttgtttt tgtccccccg acagttgttt
    18421 aggataagca gatgcttttt cttccaaacc gacaagttcc agtagttcat tcactttttg
    18481 acgacgttcc tgtttcgatt ttccagaata ctttaaagaa aaatcaacgt tgtcaaaaat
    18541 agttcggctt tccattagat tgaaatgctg aaagatcata ccgatggcct ttctttcttt
    18601 tcgcaattct ttgggagaga gctgactcag attcgtctga ttgacaatga cttctcctgc
    18661 tgttggtttc tgcagcaaat tcatcacacg aactaacgta cttttccctg cacctgagta
    18721 accgacgatt ccataaacat cgcctttttc aatcgttaaa tctacagaat ctactgcctg
    18781 tatctctttt tctttttgtt tgaaacatac agaaacatct cgcaattcaa tcattaaaat
    18841 tcctccttat ctaaaaaaag cgtcctcaag aaaatgaaaa tgtcattttc ttgaggacgc
    18901 ttttttgcgt gttaccacct catgttcaag ctgtgttcac acacaactcc tcttcaagta
    18961 cgatcatact ctagcaagat atcggtcgca gccgtcatcg ccttacatct atgctcggga
    19021 tgaattgctc gatggccatt ttccaatagt cgttccttgc ttcttctcag ctaccgaagc
    19081 tctctgtcaa aggttcttct atcgtactta ccatttcaat gcaaataata ttcaaaaaaa
    19141 aagtcctttt actaacataa actatgtcag taaaaggacg acgtatcgcg gtaccacctt
    19201 ttttcggaag tttccttccc tcaagcccaa catctcaaaa agagagattg gcgttcgttt
    19261 taacggtcga acagttccga atttgcctac ttatcgacaa attattctcc aaggccattt
    19321 tcagcttttc ttacttgact cttctcacca gccagagcct ctctgcaaag tttccaaact
    19381 tactttcctt ttcaacgaaa tcgatatttt gttgttggga ttaatctaca tgaggaaaac
    19441 tgaaaagtca agtacgaaat tcaaattatt ttttctatat ttatttttct gtttttttat
    19501 ttaacatttc aataacagtt cgaagatctt ttccttccgc aagaagtttc aatttttcct
    19561 tttcttcgac ggtataattt cggacaaaac tggaatcagg tatcaaaaca acgcctaatc
    19621 ctgctcgtga agcagctgtt gctcctacta aagaatcttc cactgcaaag gctgaactag
    19681 cttctaatcc tgttcgttcc aaagctgtca gataaggaat cggtgaaggc ttgttctccg
    19741 acacttcgtc tccgaatgta aacgtgtcca agtaatcagc taatttaaag tgatccaaga
    19801 tatctgttgc tcttttcgta acagtggtcg tagcaatgcc tagtttcata tgacgttctt
    19861 ttaagtctgc caatatttct tttgcatatg gttttaagtg gatggctccg cttgtcagct
    19921 gttgataaaa atattcttca cgcttcgctc ggacttcctg tactttttca gggctacctg
    19981 ctgctttcac taaaatatca aaactttgtt tccagttttt tccgccccaa gcgtcaacga
    20041 tttcttttgg gatatggata tcaaattgct gaaatcccca aagccagcca tcacgatacg
    20101 ttttttctgt gtcaactaac aaaccatcta aatcaaatat tgcacctttc atctatacat
    20161 taatcctttc caaaacaata cacatagttt agcacgactg gtccaaaaag aacagaagca
    20221 aagaaccagc cttctcgttt ataagagttc ttggaatcga cggatataga ttttcttcac
    20281 agctgtcaca agcgccagat aagcgatgac tgtagcaaat aaccataacc agtaattgcc
    20341 aggaagtggc atcaagccta attcagcacc aaaacttgta aaaggaagga cagaaccgac
    20401 aataattcct aatgtagtga taacaaacat ggcaaatgtt gcgttgcttt ggataaatgg
    20461 tactttcggt gtacgcagtg catggagcac taaggtttgt gtccatagtg attcgacaaa
    20521 ccatcctgca tggaataatg cgatgaaaat cactcgctgt gaactatcca atgtatggaa
    20581 acttccgccc actacagcag gacaaataac aaaatacatc aacaagtaag tagtaatatc
    20641 aaatatcgaa cttgttggac caaagtaaac catgaattcc ccaatactag atgcattcca
    20701 tttttttggc tcgtccaaat attctttatc catccgatcc catggcaagg aaatgcagga
    20761 aacatcatag atcagattca aaaacaaaag ttgtaaaggc agcattggta aaaatggcag
    20821 gaacgtactt gcaatcagca cggaaaacat attgccaaaa ttagaacttg ctgtagcctt
    20881 gatatatttc atgatattcc caaaagtttc tcgtccagaa agaaggcctc tttccaaaat
    20941 cgtcaaatct ttttctaaaa ggatcacgtc tgcagattct ttcgcaatat ccacagctgt
    21001 atctacagaa ataccgatat cagccacttt cattgcagga gcgtcattga taccatctcc
    21061 taaaaatccg acagtatgac catttttacg taaagctgtc gtcaaacgtg ctttttgctg
    21121 aggattcaat tttacgaata cttcatggtc ttcagctact tgtgctaatt catgatcact
    21181 catttccgag attttctcac cggtaaccaa ttcattgatc tctagaccta cttgacggca
    21241 cactgaacgt gtaactaatt cgttgtcccc agtcagaact tttacagcta caccatgttc
    21301 tttcagagct ttcaacgctt gtttcgttgt ttcttttggt ggatcaagga aagcaagata
    21361 accaatcaaa accatgtctg actcatcttt gactgaaaat tctccaacga cgcttggatt
    21421 ggtcttttgt gcgacaccaa tcactcgtaa gccatcttca ttaagtgact gtacttttgc
    21481 aagtacggct tcttttcgtt cttttgttaa tggtgtaaca gtaccgccaa gatcaataaa
    21541 tttagaaatg ttcagcattt cttcaatcgc gccttttgtg atcatttgtg ttttaccagc
    21601 tggatcagca accacaacac tcatacgacg acgttcaaaa tcaaaaggaa tttcatccac
    21661 tttttgataa ttgatcttat ctgtatctaa agtttctgtt gcttcatcaa tgatagccac
    21721 atctaacaaa tttttcagcc ctgtttgata gtagctattt agatacgcat ggcgcaaaac
    21781 acgatcatct tcatttcctt cacaatccat atgatattca agaatgattt tatcttgtgt
    21841 caatgtcccc gttttatccg tacataacac atcgattgca ccaaagttct ggatggcatt
    21901 caaatttttg atcactgttc cttttttggc catcacactt gctcctttga ccaaattcgt
    21961 cgtaacgatc attggaagca tttcaggtgt tagaccaact gctacagata gtccaaaaag
    22021 aaaagcttct agccaatccc cttttgtaag cccattgatg acgataactg ctggagccat
    22081 caatgacata aatttgatca gtagcatgga tgttttatgg atgcctaatt caaagcttga
    22141 ttgaattggt ttttcagata gcgtttctgc tacatgacca aatagtgttt catttccaac
    22201 agaaacaatg attccttccg cacttccact gatgacatta cttcccataa agacaagatt
    22261 ttcgtaactt gtttcgcttt gctgatcgtc ttcacatact ttcgcatgct tttctactgg
    22321 atagctttcc cctgtcaatg ctgcttggga aatgaataaa tcctttgcgg acaataaacg
    22381 catatccgct ggtatcatat cccctgctga aagccgaaca agatctccac agacgatttc
    22441 ttccatagga atctctgtgt actttccatt acgttttaca gctgccgtta ctttcacaag
    22501 tgatttcagt ttttcagccg cttgattgga acgtacggac tgaatcaacg tcattgtccc
    22561 gctgacgata accatagtga agataatggc tacaccgaaa agatctttat ctccaggagc
    22621 tgctaataca tattccgtga tgaatgaaat aattcctaat gcgatcaaca ctaatgtaaa
    22681 tggcgtgatg tatgctttca atatttctac aatgaatggt gtttttttgc catatgaaat
    22741 cgcattttca ccgtaatttt ctcttgaacg ttcgatttgt tcttctgtca atccatttgc
    22801 tgatgcatgg aatagttcaa ataattcttg tttcgttttt ccagcaaaag ctgcatagat
    22861 tttttgtgta tctttctttt tttccatctc aatctctcct ttgtgtccaa aagacagctg
    22921 ttctcgctgc ttttggtctt tagctattca tcggatcgat agagaaaaaa ctgaaagggg
    22981 ctgagaacag atagataata gccctggcct ttcctctaga tccttgtttt tcgaatgact
    23041 gtcatccatt tgttctcatc tcctttacta agtaatttta attcatgact tccaatcatt
    23101 tttcgaatag ttatttttcc aattagacca cctccttttt atttttcacc gatggggatt
    23161 tgcggcaaca aaaaaacctc tcgccaaata ctcagcgaaa ggtttgaaaa agcatattaa
    23221 aaaaagcttc tcagatctca tcgttgagtt ttgacactgt acaacgtaaa aagcagatac
    23281 ctgcttttag ctaccttatg aaaagcctta tctcgacaat tcctgttcta cccattggcg
    23341 tctctcgacg tttttgggca gtagcctatg tttgtatagg agcctcacct aacaaatctt
    23401 attcggtttt ccttcgttaa tataacaact aaaaaagagg atgtcaaatc aattttccat
    23461 gtttttcata ctttttttaa aatacacacg ttatattcct gtctcacgcg gttttatttg
    23521 tctcattttc cacctcccgc tataatagaa atatagtagg aaacgaggtg ctgttatgga
    23581 aagaacactt gttattatca agccagacgg cgtgagacgc catttagtcg gaagcatcat
    23641 ccaacgtttt gaagcaaagg gactggccat tgctgaaatg aagtttgaaa ctatgactcc
    23701 tgaattagca aaagaacatt atcagcactt gactgagcgc agtttttttg atgaactgat
    23761 cgattacatg acttccggtc ctgtcgttta tcttgtgctg gtcggcgagg aagtgatcga
    23821 tatcgtccgt aagatggttg gagcaacaaa agctgccgat gctgttccag gtacgatccg
    23881 aggagactac gcgctgccgg ggactgaaaa catcattcac gcttctgatt cccgtgatgc
    23941 tgcggtaaaa gagatcgccc gctttttccc gccattcgat ataaacaaac cgtctgaaaa
    24001 agcggcgaag tgatacaaat tctaaactgc tggtctagtt gctgggttca gcaatggcca
    24061 gcagtttttt ctctaaggac ctccgttgat tctttcctaa catatattcg agcactgtga
    24121 agaattcttg gtagtctttc gtcttttctt cccctaaagc agcagaaatc aatctttgat
    24181 aataatctgc catcaatgtt tcatagatca ctgtacttct ttctttatgt gataagctcc
    24241 gtttcatatc ttcattcaca ctacgtgcct ttttcaaccg accattttct atataaaacg
    24301 aagtcaggtt cattaaaaaa gtaaagagat actgctcatg attgttcaac tgtgctaatc
    24361 gtcgcattct ttttttgatt ttcaaataat tgttctcaat gaaccgatca ctgaatatcc
    24421 aaggaaaatc agctagaata gatagttcaa attgaccata gtctggtatc tgcatcaagt
    24481 attcttcaat gattcggcat tcataacgta aaaattcaaa ttctgtctca gatacttctg
    24541 ttttttcgac catgtgaaga ttcaaaacca aataatacag atcttctgtt ttcttaaaat
    24601 gcctacggtt attgctgatc tctttataag gatcaaagct gtcttcttgt acccgatcta
    24661 gcattcgtct ttttttcttt aactttattg gttcatccag ctggtttcgc atccattcat
    24721 attctgcaag tgtcatgttc attcgctcta aaaatgatct caatgttaca aatgacattt
    24781 ttttcactga atttgtctca atcccgacta gagaagtctt aaaacagatt ccttccgcta
    24841 attgggactg tgtcaacttc ttgttgactc gaagtttctt gatcaattca ccatcataca
    24901 taatagttct cctttttaat ttaaattttt ccacattcaa taaatagata cgttaaaaag
    24961 gaaaaataca cgaaaaaaat aaaaaaatgt ttttttcata aaaaatacca accttcaagc
    25021 attagaatgt tgtctaacta ctgaaggttg gtttgattgt ttattgatta tttttttgct
    25081 gttcaacgtc tgttcttgtt actggatata agttggttgt tgttttatta ccattttttg
    25141 aaaagacact tgtcgaatgt tcgccttttt gcttttcgat tgcttcatta cgttccgctt
    25201 catttttata gtcatatttt ttcggatcaa tcgtctcaaa tccgtttggc acataaaacc
    25261 gcaagagatt ttcctgattc agcttatctg aaagacttaa cgcagtcttg actttttcct
    25321 gatctttgga gatttcctca tcgattcctg ctgctttcgt atcgatgatt tctcctgtct
    25381 gattattgta agcttttcct cctaggacgg tgtatttggg tgtcacaaag ttcccatttc
    25441 gaaaagcaac tacttgatca tgctgagaag ataataagtc tgtaccaaaa tgaagataat
    25501 ctttatcatc gattcccaat agatgtagta atgtcggcaa aacatcgatt tctccaccgt
    25561 attcatgatt gactgtccct ttagtataac caggcatatg gatcatcaat ggcactcgtt
    25621 gcatctgtgc gttgtcaaat tcatcccatg tatctggatc tttaccaaga gcgcttgcta
    25681 aatctttatt atctgtattc gagatcccaa aatgatcccc gtaaatcaca aagattgaat
    25741 tttggtaaat accagatttt ttcaaatacg taaaaaattg ttccaatgat tgatccagat
    25801 aatgtgccgt tcgaacataa ttatctactg tgctattgcc agtattcaaa gatggaaagt
    25861 cgaaattctt gtcatccgta taataaggcg tgtggttggt tacggaaaga aatttcgtgt
    25921 aaaacggctg ttgtagatgc tcaagatatt gggcagattc tctgaataaa tctttatcta
    25981 atatcccata acctaacgtt tcgtcggatt catcaaaata agatcgatca aagaaattgt
    26041 cataacctaa gtttttatat acatgatctc tattccaaaa actagctaca ttcccatgga
    26101 aaacagcgct tgtatagcct tgcttttgtc caaggatcgc tggtgcggct tgaaagacat
    26161 tgtctgaccc aagttctgtg aataatgagc cttgaggtaa accaaatgtg ccagtttcca
    26221 acatattttc agcatcactt gtctttccct gtcctacttc atgaaagaaa ttgtcaaagc
    26281 tgatcgttgc ttgattctgg aaaatactat ttaaaaacgg tgtgacttct tgtccgtcta
    26341 ccttcatatt aatcaaaaac tgctggaaac tttctaaatg gagaacgatc acatttttcc
    26401 ctttagcgat cccaaatgtt tcgggatttg gctctgcata atgtttcttt gtataatcta
    26461 aaacttcatc aatcccatta ctgcttgcat gcgcgcgaac actgctagtc attcctgttt
    26521 tgattccgtc ataaatagta tacgcatcga ttcctagata tttgacaata tatgaacggt
    26581 caaatgttcg ctgcagcaat tgtggacggt tggcttcgct cagcgctaga tttcctgaaa
    26641 aaataagccc tgaaagacag gtaacagcga tagccatcgg tttgccgaca gggttgcttt
    26701 tgataggtat tttcttgacc ttcaaccaaa ccagtagccc aatgaacaca gcgatatcca
    26761 gccagtagat gacatcatgg ggcttcatca aagaaaagga gcttcctgac aatccttgcg
    26821 acactttcga aaagcctaat acagatttga ctgtaatgaa atctgtgaat tcccgataaa
    26881 aaataatatt caagtacaac aaaagcgtat ttaaaatatc aatgatcaaa agaatagcta
    26941 acgctggctt tggcttttta atatacaaag aaaggccaaa aaacaataag gtagtcgcaa
    27001 ttgggttgat ccacaagata aagtactgga tcgtaccttc cacacctaat gaaaaatctg
    27061 catagtaggc aatgatcgtc ttcagccaga aaaagaaaac agctgtcaaa acgattgcta
    27121 aacgattttg gcacaatttt ttaagttgtg tcacgtatat cacttctctc tattcacatt
    27181 ttttcttatt ttgctcctga aaaatgaaaa tttcctaaaa aagttgttat cttaagattt
    27241 ttttattctt tctaaagatt attccgtcca cttttcacag cataaaaccg ctgcgatgta
    27301 agcgattaaa ctaatgaaga gataaaagtc ttgtggtgac cgcttcactc cacggtattc
    27361 aaaagccagt ttctcggtat tcgtacaaaa aaagaggctg tgacaaaatt cttgtcgcag
    27421 ctccttattt cttgatgcag gacagctttt tcacaacttc ttccttaaac ggtgttctcc
    27481 tgccaactcc tcggccacaa gtcacaatat ttataaaaca tgagaagctg ttttttgaaa
    27541 ttgttccttg tggctcagag ttaaacggca ggctcaagac ctcttgatac acggtgttca
    27601 atcagctgac cctcggtatt agattatgtc aggacgctaa ttttacaacc tcttggtaaa
    27661 cggtgttcaa aagcttgcat ctgcggtaat aagcccaacc aaacgaaaaa tataaggagc
    27721 tattttttga aattgctcct tgtggctcag agttaaacgg caggctcaag acctcttgat
    27781 acacggtgtt caatcagctg accttcggta ttagctcaaa aaacggcaaa atatgaggaa
    27841 ctattttgcc gtttgtttct ctaatactca ggtcaaaacg ctgatttcac aacctctgtt
    27901 tttcattgtc cataggattg atattgtcct tgtgatgact cattcgtaat aattgaggct
    27961 tgattttctt cacttcccgt tatcgtttgt ccactgccag aatctgaagg acttgttcct
    28021 gtcgactcgt ttttttgaga agagacagtt gttttcttga cttgttcatt tgtctttttc
    28081 cattccgcta aacgatcggc gaccactttt ttgtctactt tttcagaata agcggtgatc
    28141 acttttccat ttttcaaacg ggctactttg tcgccatcat gagtcaaaag caaaacggtc
    28201 aaatgcttgt ctttaaattg atattgtctg agagaaatcg cactaagtac gtcatcgata
    28261 ttaataaatt gattttcttc ttttcctttt ggcaaataaa tgtccaattc gcctttttcg
    28321 taattggcag ttattttata ctccgcccac caataagttg agaattcttt tttgaaatta
    28381 tctactgatt ctttgcttgc tacgattttt tctgtttctt tctgagcaag atctgctgtc
    28441 atttttcctg aaaatgctgc ggataaaata agcagtaaga aaaaaccgaa taaccaaaag
    28501 agaagaaacg gtcttttttt cctcatgctt tcctccactc ctatttaatt ttgactattc
    28561 tattatatac aaaaaatgaa atagaaagac aaaaaagttg aaaaagatcg taaataattg
    28621 aacttctttt tcacaaaatg gtaagaatgg agaatttcac gcatttgctc tcaactattc
    28681 tttcttaagc ctcaaatccg tttttatctg atacgtcttt gaaccaatga cccgattttt
    28741 tgattgttct ttttccatct tgtgctaagt ctactgaaat aaagccatat cgattcttat
    28801 atgcattggt ccacgaccag ttatccatac atgtccacat atgatagcct aaacaattgg
    28861 caccttcttg aatggcttga tggacatatt tcagatgaga ttggacaaat tcgatccgat
    28921 aatcatcgtg gatcatgcca tcttctttga taaatcgtgc ttcgttttct acacccatac
    28981 cgttttcaga aataaagcag tcgatatttc cataatgatc tcgtacattg atcaaaatat
    29041 catagattcc ttgttcatag atctcccatc cgcgataagg attcatttta cgaccaggca
    29101 tttcataatt gtcgaaataa tcctcaggca ttggaccgtt tttagtatcg attggtgttt
    29161 cttttgcttt tacccggcgt ggctggtaat aattgatacc taaaagatct actgtatttt
    29221 ctttgataac cgtcaaatcc tctgcatgga tcacaggcat gagatcaagt tcttttacta
    29281 tctcaatcaa ttcacttgga aactcgcctt ttacagctgg atcaaggaat gaacgattga
    29341 agaacgcatc tgctatttgc gctgctttaa catcttcagg gtttgattcg tctcttggat
    29401 agcttggtgt cagattcaag atgataccaa taacaccacc ttgctccatt tcatggtaag
    29461 atttgatggc taacgctgaa gccaacgctt catgatagcc aacttggatc gcttttttca
    29521 tatctgactc ttctggataa tgccatcgat ataaataacc tgcttcgact ggaacgattg
    29581 gttcattatg agtaaaccat ttttttactt tcgaaccaaa caattcaaaa caacttttgg
    29641 catatttttc ataggcttca accgtttctc ggttcaacca tccgcctttt tcttgcagat
    29701 acatcggcat atcgaaatga tacagattca caaagggttc gataccgttt tcaatcaact
    29761 catcaaaata acgatgatag aaacgaacgg cttcttcgtt gattgttcca gattcatcag
    29821 gtatcaaacg gctccattgg atagatgttc gaaatgaatt atgcccagtc tgtttcatca
    29881 actgtacatc ctcttgatac ttcgtataaa cttgcgaggt tttttcaggt cctacttgat
    29941 caaagaactt ttgcggttct tttttgtacc aataatcaaa aatgttctct ccttttccat
    30001 cgcctgaaat ccttccttct gtttgtgggc cacttgctgc agaaccccac caaaaatttg
    30061 ctggaaattg atattttttc atcaaagcac ctctttttct tttttagttc gttttagttg
    30121 attccatgta tgatattttc catcacaatc actttttcat tttcttcctc ttcttttttg
    30181 attcgtttta acagctgttc tgctgctcgt tccccgattt tatctgttgg tggcgtgatc
    30241 gtgattttcg gaaggatact cagatcgttt ttatctaaat aatcatagtg actgaacgca
    30301 atatccttcc cgattctgac accttcttga ttgaaacatt cgatggcacc aatcgacata
    30361 ttgtaattgc tgacaaaaat agcagttgcc cctttttcta ataatgcttt tgccccgtaa
    30421 tagccgcttt ttctagaata gtctcctgta aagacctcta attggatcga tggatcattt
    30481 tggaccgctt ctttggctcc tgctaaacgt tctcttgcta cgtagtctgt ttgagtggca
    30541 gcaataaatc cgattttttt atgtccttgt tcaccatgat gagcgatcac ttttgctaca
    30601 ctttctcgat cattcactaa tattgtatca atacctgctg gtccttctgg acaattcaat
    30661 gcgataactg gaatactcat ttttgtgagc atttcaaatc cagaccactc ttcttcggat
    30721 aagaagacaa tcagcccatc gatcacatgc ttcatcaggt attcaatttt ttgttcaatt
    30781 ttttctggct gatcggcaaa cccgcttaat aataagctat acccattttc ttcagctact
    30841 ctttcgatcc ctgagacaac ttccgaccca aaacggctgg aaatcccgtt tatcaaaagt
    30901 ccaatagaga agcttcgatt attcttcaac cctttagcaa tgatgttttc tttatagtcc
    30961 aacgctgaaa tcgcttctgc tatttttttc atgttctttt ccttcagttg ctgaccattc
    31021 aagtaacggg aaactgttcc cactgaaaca ccagccatct tagccacatc acggatcgat
    31081 gccatacatt ctcactcctg ccagttacat ttgatttctc tttcttgttg ttcgattatg
    31141 atgaccgcat tctttgcata gtgttgcttg tcatcaatat ccatataact aaagtcttca
    31201 gtagagcaac ttcctctcac tattaattat acttaaacaa gtatttgaac cggttcattt
    31261 ttaatatagc atttttttaa aagattgcaa cactttttta aaacgctttc tgaaagtggc
    31321 ggattttttg cctttttaaa attttattct aaaatttact ctatttgtgg gtgttttgtg
    31381 cgtttttctc ttccatccgt ttgaagtttt acattccaat ggtataattt ctttatccta
    31441 tcaaatgggg gaagtatttt gaagaaatta atcgtactat ttattttgtc tgcgggactt
    31501 ttgacattga ctggctgtga tttgtttggc ggctctgacc aatcctcgga cgaaacaacc
    31561 gattcttctg tcttaaaagc ggaaaaagca gataccacca acagtgtata tacgctaaaa
    31621 gtacgtaaag atatggattt atccgcggga cagttgacat ttacagataa aaaaatggaa
    31681 tggacacgca cgtatcagac acaaggaact gattcttctg aatcatctga agaaaaaaca
    31741 gtgctgacag atatcaagat cactaccaaa gatgacgaat atattatttc aggaaaagaa
    31801 aataaaaaag aaacaacagt catatttaca aaaatcggta attaccgttt gaaggatgag
    31861 gatggcaaca tctacagtct atagtgccgt ctgttggatc ttcttttgtt tctccccttc
    31921 ttttctgcta tagtaaagaa gcaagatgat tgtaaaggag acgaaatgga tgatcgatag
    31981 tcctgattat tgtacatgta ataacaacaa aaatatccat acagaattta atgaccaagg
    32041 aagcttgagc atatgcgaca actgtcacaa actagtcaaa gattcattta aaacatttga
    32101 atcttatcct gttcaaaatt atgtaaaaag tagaagaaga taaacaaatc caagcaaaac
    32161 tcactatggc tgatttttat gaacttcaaa ctcagcttct tcctttgatc aagcttcatc
    32221 agtaaaacaa acagtggatc atttcagttt acaaatcaaa gagtaaagat ttatttattt
    32281 caaatatttg aatataaaat aaccaaacga tagaaaggct tattctacat cacgtagtaa
    32341 tttttctttc ccgtcgtttg gttttttatt tttagcctaa ttcttgacct tttgcatgct
    32401 ggttatccgt aaaatatttt ccagcaggct ttccttccaa ttcagctaat ttttcttgga
    32461 tctgacggat cacctttttt gcatcttctg gattttctac aaaatcgaat ttatccccat
    32521 ccacttgtat tttaggacat acatcaaaat cttcatacca ttgattatag cgggtgttca
    32581 acgtttcata ataggtatat aacgtctcat cgctttctag ctgttcatag tcacgcccac
    32641 gttttttgat acgttctagc atcgtgtcca aagaaacttt gatatggacc atcaaatcag
    32701 gccgtttttt tggagcaaca tcatctaact cgtttagcat cgtatctaat aagctatcgt
    32761 actgctgtac ttcgatatcc gttacccgac ctaaatcagc gtttagatgg aacaacaggc
    32821 tatcttcata gatggatcgg tctagcacat tgtcatcgtt cactaaagca tttttcattg
    32881 ctaaaaatcg cttgttcaaa aagaagattt gcaataaaaa agcgtactgc tcaggatttg
    32941 aataaaagag cggcaatact tcgttatctt cgacattttc ataaaatggt ttagaatcaa
    33001 tctcttttgc aagcatatcc gtcaaactgc tcttacctgc accaatcgtt cctgaaatca
    33061 aaatcactga catacaaccc ttcctcttct ataagtactc gcctacgtaa gtttcaacag
    33121 gcaatgtttc aaaatcatat tcacgtacag cttggtctga ttttaaatac gtatggagac
    33181 tttgtgtaat catcaagttc gtaggtaccg tctcttcttg tacaatgatc atcggttttt
    33241 tcaacatagt tgccacacct aattcgtaag ccgttcctgg atcgattgtt tgatgctcaa
    33301 agtcaaggat agcaacaaca aattctgcat ttgtcagttc ttccatatct ttttcgtata
    33361 cttcctgcgc ccatccagcg ctgaatagtt cataattgct ttcttggtga tgacgtggag
    33421 agtagaaact tgtgactgtt ttgttttcct ccaacgcttt ttcgatacga cttactcgat
    33481 cgatttgctc ctctgaaaaa aatggtcctg ctaaatatat ttgactcatt attttgcctc
    33541 cttcaataat aactgatttt taatagatac tgctcgtaat tcattgacca gttccaatgg
    33601 attgttggaa aagattactt gatccaacca ttttttatcc ataaaatcct cttttgcaaa
    33661 agtttctaat aattgttgca agccgctgta ataaccgcca atattcaata ttccgattgg
    33721 cttgtcgggc gtcagaccga ttgctatcca agaaagaagt tgtgagaatt cctccaatgt
    33781 acctagacct ccagggaaaa cgaggacagc atctcccttt tcaaataata atacctttct
    33841 ttcatcgatc gtttctgtag gaataaatgt agtaacatct tttccaggca attcagtttc
    33901 aaaaagccca ttcggataga tacctgtgac ttttccgtta ttttccagta ctgttttact
    33961 aatcactccc ataatcccgg agtatgaacc accgtaaacc agttcgattt cttcttgtgc
    34021 catgtatttt cctaacgttt gcgcaataaa tttgtaactt tctttattac caaaacggga
    34081 accgcaaaaa acagtaagtt tcataaaaaa acactcccta actcaaaagt ctatcttcat
    34141 tctacacgtg tttttttaaa ataaaagact agattttgta gttttttagt ggtatatagg
    34201 atagacgcca ctatatatag tatttagaaa aaaatcattt ttcagccatt ttatagataa
    34261 aacaaaaata aataacgtgt tttcatcgat atgaaatgac ttacttatag aagatactgg
    34321 gatttcgtcc tatatgccaa taacgtgtat tattttaaac aacaaatact tgtttctttt
    34381 attaacgaaa aaatcatttt gttctcgtgt tatgtttcac tgataaatga tgtttctcta
    34441 aataaaaaag ccgacgaact aaacgatcaa aatttgatca tttttgttca tcagcttctc
    34501 ctaaaaatct ttttgttaac gataaatagc tggatttgta aaaatatcac ttgaatcgtc
    34561 actgctggaa gaaaattcag tgataaccgc acctgttgcg cctgcctgga actagtgttt
    34621 gatattgggc tcgaacgtgt actgatctct agcatgaaga ataatttctt tttttactgt
    34681 ataataactt tctttccttt ttggaatagt acaggaaagt ttttttgttt cctttccttc
    34741 gacataaggt ataccagacc ctttcgacaa cgaaaggttc tcatttttcc ttcatcgtca
    34801 tttcaaggag ggtgccgatg ctctggacag tttcgatcgc tcctaaacca aaatctgtat
    34861 attcgattct ttctaactct gattctttca taccattcct gtctcaaggt acatctattg
    34921 tacttttttc ttgtaatcca ttctgcctct cctaactaat tgtcaaatca tcccaagata
    34981 tgtcttcttc ctctttttct tcttggatga tttctgcatt cggatctact ggttttttca
    35041 ataataaaat ggttattcct gtgacaaaag aaccagctaa caatgcacca atgaatgccc
    35101 atggtctggt catcgtagcg actgcaaaca ttcccgatgc cggaatacgg ctatctgcgc
    35161 cccaaaacat gcttaatccg ccacctactg tcccaccgac tcccgttgct atgacattgc
    35221 gtgccaagtc gttcaatacg atagggaaac atccctctgt gatctgacag atccccatag
    35281 gaaaagcggt cttcaatgta tcgatttctt gacgattgag tatattttta cgaatgattt
    35341 tccctaagaa ataagcgatc gtcaagccga atggggttac catcgaagct aaaatcaata
    35401 cagtgattgg ttcatagatt ccttctgaaa atcgtgccac acccccttat ccagaataaa
    35461 tggtaatcca gaaacagccg tgtatctgcg gtaataagcc taaccaaacg aaaaatatga
    35521 gaagctattt ttgtttggct gttcttatta cttgatgcag ggcagctttt tcacaacctc
    35581 tttttttatt tatgtttcat aatcaatatg gtaaggatgc agctccgtat ggtagaccgc
    35641 ctccgaatat tcaatcattt ccccaatttg cgtagacgat ttccgtatcc gtttgatgcc
    35701 gatctgtgcg tctgttttca gaattccttg ttcttcttct gttaaaaata ctgccgagaa
    35761 atcatcagaa aatgagtcaa tagtatatcc ttttttcgtc agcaaacgat acaaagattc
    35821 tttgccaaat tcttctctgc tgaattgcat catttcttgt ggaagataat gaacaaaata
    35881 aatataaggc tgattgttca aataatataa gcgcttaaaa caaacagctt gctcaccgaa
    35941 aaaggaaaac aaaggatctt ccttctttat atggaccaat tgcaaatcca gcgtttcttt
    36001 ccggacttca tatcgggagt tctccaagat ttgcgtaaag cttgccgctt tggataatcg
    36061 attgtaagga cgattgctta gaaccgtcgt cccacgacca cttttctttg cgacatattc
    36121 atctgatgcc agcagttcga ttgcctttcg gacagtgatt ttgctgactt gaaacagttc
    36181 ttctaattca ctttctgtcg gcaacatcga accgactgga tattttcctg agaaaatatc
    36241 ttctttaatt ttatctgcga cttccaagta tagtacacgt gtccttttca taacgtcacc
    36301 ctttgcttta ctattactaa aagaatagca cataaaaaat aaaaaaagaa cacaaatcac
    36361 atgtgagaag tgtgttcttt ttcattcagc tgctttaatt acaagtttac gccatttgag
    36421 gcaattactt ctttatacca atcaaaagat tttttctttg atcgattcag tgtcccattt
    36481 ccttcatcgt ctagatccac atagataaag ccgtaacgtt tactcatttc tcctgttgat
    36541 gcactgacaa gatcgataca tccccaaggc gtatagccca tcaaatctac accgtctgct
    36601 actgcattag ccatcgcttc gatatgacga cgtaaataat cgatccgata atcatcaata
    36661 atcgtgccat cctcttccat atgatcaatg gctccaagac cgttttcaac aatgaataat
    36721 ggtttctggt aacgattgta taattcattc aatgcgattc tcagcccttc tggatcgatc
    36781 tgccagcccc attcacttgc ctcaagaaac ggatttttta ctcctcccag caagttccct
    36841 tctgaagttg ctgcttgtgg atcagtctca ttgattgccg tagacatata ataactaaat
    36901 ccgatgtagt ccactggata ttcttttagc aactggaagt ctttttccgt ttgctctaat
    36961 ttttccggat cgactccata ttttttatgg gtacgcgctg tgtatgcagg gtattctcca
    37021 cgtacttgga catccgtgca gaaaaaattg aattcttggt tttggatcat tgttgctgcc
    37081 tgattgactg gattggcatc gatgctgtaa gttgttgcat agataatcat gcagccgatt
    37141 tggatatccg aacgcaattc gtggccgatt tttacggctt tgctacttgc aacgaattga
    37201 ttatgccatg cttggaaaat attttggtac tctcctgctc cattgctttt tactaatcct
    37261 tgacttaaag ctggaaagtg aaaggccgaa ttgatttcat tgaaagtcat ccaatatttg
    37321 actttactgc tgtatctctc taatactgtc tgagcaaatc gttcatagaa gtcgatcagt
    37381 tttcgatttt tccagccacc gtattctttt gccaaatgaa gaggcatttc gtaatgagaa
    37441 atcgtgatca caggttcaat atcatatttt aagcactcat caatcagctg atcataaaat
    37501 tctaatcccg cttcgttagg agtaccttcg tctccatttg gaaaaattcg tgtccaggca
    37561 atcgaaaaac gataacattt gaatcccatt tccgcaaaca aggcaagatc ttctttgaaa
    37621 cgatcgtaat gatcgattcc tcgatgattc gggtaaatat atttttcttg atcaatcgtc
    37681 cagtcaaatt cttcactgcc gataatcgca aagcgctgct tacctccagg catagcatct
    37741 gcaacggata gtccttttcc gtctcgatca taagcccctt ctaattgatt tggcagcagt
    37801 tgctccaccc cataaaaatt tttctgaaaa acgtgattgc atcctgattt cctccttatt
    37861 ttacaattgc cagaacatct tcgtttgcaa taatctcttt ttggtctaat tcaagtatat
    37921 cggcaaatgc atcagtattc gtaatgacaa ctggagtgat tacgctatag ccagctgctc
    37981 taattgcttc gatgtcaaaa cgaatcaata aatctcctgc tttgacgaga tccccttgtt
    38041 tgactaagat ctcaaagcca ttcccattta attctactgt atccatcccg atatgaatca
    38101 aaatctccgc tccgtcagtc gttgtgatcc ctacagcatg tccagttgga aaaatagtcg
    38161 tgatctctcc gtctgcaggt gcaactagtt ctcctacttc tggatcaata gcgatacctt
    38221 ttcccatcac gccagaagaa aaaacttggt ctggtacttc actcaatggc agtactttac
    38281 ccgttaaagg actttttaag gtatgccgtg ctgaagtaat cggttctcct gcattcgcat
    38341 gtttgttttc taattgattg tcttgtgttt gttcgtcaaa tcctaaaatc aatgtaccta
    38401 cgaatgcaag aacaaaagca attcctgtag ctattactgc tactgtcaca tttgactcta
    38461 caccatccac cgtattaatg aaagtcggaa tcgtcaataa gctgaccaaa ctgctggaga
    38521 aagcttttac tccggaaaat ccgataatag ctccaccaat acctccagaa atacaagcgg
    38581 caatgaatgg tttcttcaaa ggtaatgtca caccatacac agttggttca gtgattccaa
    38641 ataacgaagt cactgtagaa gaaatcccta atgctcgaag tttcgtatct tttgttcgca
    38701 atgctacagc taaagcagcc ccaccttgtg ccaagatggc tggaagaagc attggcatca
    38761 atacatcaaa cccatattgt tcgatattca aaaacatgat cggtacgaat ccccaatgca
    38821 tgccgaacat cacgaatact tgccataaac ttcccatgat tagacctgct acgattggac
    38881 taaatccata aatcgagttg aagagaccgc ctaaagcatt accggcaacc gtcccgattg
    38941 gtcctaaagc aagaaatgtt aatggaacca tcactactaa aacgacaagc ggaactaaaa
    39001 tcatttgcag aaattgcgga atcacttttt ttacgaatgg ctctaattta ctttgaaccc
    39061 atacggctag aatgattggt atgacagaag aagtataacc agatggtgaa agaatcactg
    39121 ggatcccaaa gaaactgata gcttctcccg caccagcaac tgctgtgata gctggataca
    39181 caagtgccat agcaattgct actgctaaaa actggttggc tttgaacttt ttagctgctg
    39241 taaaagcaag catgacaggt aagaaggtaa agacaccatc tgctgcagca aacaatattt
    39301 gataagtacc gctatcagct gtcagccagc ccatcaccgt tgccaatgat aagaatcctt
    39361 tcaatacccc ggcggctgcc atcgccccta gaaaaggtgt aaatatacta gagataatat
    39421 cgatcagacg attcaaaata tttttggact cttcttttcc atcctccgaa actgcaagac
    39481 cttcctcatc cacgatcgat tgataaacat ctgctacatt actgccaatc actacttgat
    39541 actgaccgcc actttgtacg acttggatca cgtccgggtc ttcttttaac ttttgcgtat
    39601 ctgctaaaga ttcatctttt aatctgaatc gcaaccgcgt agcacaatgt actaaacttt
    39661 tgacattctt ttgtcctcct accgcttccc atacacgacg accaactgct tgattatcca
    39721 ttgttttttc cttctttctt ttttatttaa aaaataaaaa cccagattga aaaaaacagt
    39781 cacaaacatt cgtgaaccta ttttttcaat ccaggttttg cctgccatac agtaacaatc
    39841 cttatgattg gatgcttttt ttctcactta ctactctttg aatatgaatc gttaaataaa
    39901 tctgctctgc gatccccatt tcctgttttt gcgtttgtcg aagatactca ttgatccgtt
    39961 cgacacaatg aaacgctttt ggatactttc cttgaactaa tgcgtagaga aattcatctt
    40021 gctcgtcaga tccttcccct ttgagataac gctgggcaaa aaactgcaga tgagtaatga
    40081 tacgctgata attcaaagat tcttcatcga acacgatgcc gaagaattta ctgatgatac
    40141 tcagtatatc tcttaccatt gtggtagcgg tcatcgtcac ttgcatgtct tcgtttcctt
    40201 gttggctatt cacaaaatga aaggcaataa aaccggcttc atcctcagaa agttccacac
    40261 ccgtcttttg tttcacgaac aaaagagcct ctttcgctgc ttgatattct ttcggataaa
    40321 atttttttgt ttcaaataat aatggattag gcagttggat attttctttt gctcgtgtga
    40381 tcgcataatg aagatgatcg gtcaatgtca gataaatatt aggcgaaaat tcaactttta
    40441 gtttatcttc agccagttcg actacttgtt tgacccattc gatctcctct gccggaatat
    40501 cagccatcag ctgctggaat tggtttttag caaaagaatc tcttaaacaa attctttttg
    40561 gaccgcttct ggcgaaatct cgtccccaat ctttttttga aaagctagtc cttttcccat
    40621 acaaacgact tcttccccga atccattttt cgaaatgacg acattgttat tcaaaatttt
    40681 atcaattttc attttgcttc gccctctcaa gaaaaataaa aaaacctaga attcgcctac
    40741 tgtttcttag ctgaattctg gttttgcctg ccgtacagta acaatccatt tcttattcaa
    40801 aatcatcata ccatcgaatt tttatttatg caagcctttt catataaaaa ataaaaaaac
    40861 tggaacacaa gtctatctag aaaacaacca aatcagagat gcacctcttt gcgtttctct
    40921 ttttttcagc aaattggttt ttccttatcg attcatatcc tttggctgtt tttaatctgt
    40981 aacgacttat gtcccagtat cctaaaatgt ttttgtctct agattgaaag cagatctcat
    41041 atcatctgtc gcatctttta tcgatgtaac actttccagt tctccttgta caactagtcg
    41101 cgtgacggcg tccatgtcgc cacaagtaat tagtgtgaca atttcttttc cctcgacttc
    41161 attcagtaat tgggtatctg taggagcaac tttttcttta aaaaatgttt tgtatgtata
    41221 cacattttct aaatctgtca aatagatctt ggcacccatc tctaaatttt ctagcggtgt
    41281 aaacagcaat tcagggttcg ttgcacgatg gcttgctaag gcataatttc cttttcccat
    41341 ttcttgatct ggagataatg ttcctgctcc gtaaagtagt gacgtattat ccaagccttt
    41401 gaaaaccggt aaattgattg aaactgaagg gactgcgata ctagcaatca ctggtagatc
    41461 tgttcctctc atttgcgacc tcatgacccc ttctgtcgtc attggttcta ccgcatcaaa
    41521 gtcaaaactg acatctttat cgttattctt tttcagatct tcttttgtta cattcgctat
    41581 agcatattta tctcctgtct ctctgacaaa ataatccttg atctgttcat tgaaaatcaa
    41641 agctagtcct actaataaca agaggaacaa gaggatattg actagccatc tttttgcttt
    41701 tccttttttt ttcattttct ctccctccag actcatttta ctgtttttct tttgctcttt
    41761 ccaacagccg aatgacacat ttctacaact ctgtgtattt ttttcgtaca cctgcgcttt
    41821 tttctacagg atatttcaaa ttatttttga tcaatttttc ttcaatgatc tcatctagat
    41881 ccaggtgaag gttgtctgcc atcatgtatg aatagatcaa tacatctgcc agttcttctt
    41941 tgattcgttc taattgtgtt tcttttactt cttccggcgt tttccattga aaaagttcta
    42001 acaattcaga tgcttccaaa gaaatagaga tagccaaatc tttttcgtta tgaaattgtc
    42061 gccaattacg ttcatctcta aactggttga ctttttccat actattcatt tgcttgcctt
    42121 cttccaatca cttcttactt gattaatcat accatttttt tacataaaaa atagatgatg
    42181 cttttaaaaa aactcctgtt ttcttttatt taaaataaat gtcatagaaa atcaataatt
    42241 taggtagcca ccatgtgtat gcagtagcgt gtcttcttcc cttgaggctt tttgtttttc
    42301 gatacgttct tcttcccaaa cagacaacgc tactagaatc tctcttaatg attttccttc
    42361 ttcggtgagc gagtactcta ctttaggcgg gacttggtta taggcttttc gatggatact
    42421 ttcatcttgt tctaactctc ttaactgctg ggtcagcatt ttttttgtga tcgtagggat
    42481 ttgcttgctt ctccacgcct aaaataagcg atattgctct tccctttatc tggtgtaagc
    42541 aaagcagtta gcattttgac gatcgtgggt tccgcttttc acttcttatc tacttagtat
    42601 catgaagtat actttcgtac taatactaag tagcggaagt gtcaactact ttgtttaact
    42661 acatagcaaa agaaacagaa gggtgacaac ggtcatcacg cttctgtttc ttttgaatat
    42721 gctgtgttgt tgtctctatc tccgtgtaga ctttcctcaa acttatcctt tgacagtaag
    42781 tcagtaggct gatttgctct ttctagatgc cagatacatt tctacaaaaa aatagtgatt
    42841 ctgttttgaa aattcgattt ttagttctgc attttcgtaa acatccaaca tttttttcgc
    42901 actgtataga cctaacccgc catttttttt agaggttttt cctcttttga ccatctccga
    42961 tagcgtcaaa ttcgttggat ttgccttgtt cgctatacta aaacgtgatc cctctttttc
    43021 ttccagcaga ttgatcgtaa tcggactctg atcggctaca cgatgatcga atgcgttaga
    43081 aataaaaata gataaacagc gaataaaaac aaccagatca atcgggattg ttttcacttc
    43141 gacaggaata actacttgga tcgggatttt ctccgattct gctttttcta gaaattttaa
    43201 aaagacaccc ctgacagctg gggatacaat atttgttagc tgttgtattt gcggtttttc
    43261 aaaaatagct gcagaatgat cttctaatat ttctaaaaat tccaacgttt cttttttatt
    43321 ttcctgaaga gtaattttta atgaaaacag tagactttta taatcatgtt tgaattcctc
    43381 tagatgatgg taatattctt catttatttg atacagttga agcgattcct gatgttgtct
    43441 ttcttttact tggaaactga tcaacataat ggaaaaaaac aaagaaaaaa aactgatgac
    43501 tatcgacaaa agagatagaa gcagataatt agatgagcgg aagtgaacac ttcccaatac
    43561 caagtaaatc acgccccagc ttaataaaat acaaatacct ccaaaatagt gttcagttgg
    43621 ataagtaaaa agcaagttga gaaatctcgt ctgtttgtct atacttttta ctaatagata
    43681 gaaaataaat gcgataagta gtgcaaaaaa acttgctgtt ccaagatgtc tctttcctaa
    43741 ataatccatc agatcaaaaa ccagaaaaaa gctgagtcca gtgatagcaa aaaaaagatt
    43801 actgatcaaa cagctgataa acaggttttt cgtagtaaaa taaaaaagaa acatcaataa
    43861 taagccaact aggtaaggaa agctcacttt agggatagga agtaaaagtg tcaccaccat
    43921 caaagctata caaccaaagc tgttttttac tagcagttgt ttcgaaaaga ataaatagat
    43981 acctaaatct aaaatcaaag taaaggtcaa ataaagtgtc actgttgcga ccatcttatt
    44041 cctccattgt tttgtttcaa aatgtacaca tattttttta ataggagcct gcatatgaaa
    44101 aagtatttta tcatagaaga taaccagttt cacagcgaat ggatcatcag agaattggtc
    44161 aatcatcata tcgagaatat cgtgcagctc acttctatct ctcaaatcaa tcagttgatc
    44221 cagttgggca ctattgataa tcacgatgtt ttctttatcg atatcgactt gaagcaatca
    44281 ctcacaggta ttgatgtcgc cgaacaaata cgtaaaaaaa atgcacatag taatattgtt
    44341 tttttcaccg cttatacgaa ttttgcagta gagatcatca atcggaaaat ccttccgatt
    44401 ggatatatca gaaaagacag gaatttatct gaacaaattc gtcaagtgct agaacagatc
    44461 aattggaaag aacagcagat cgtaaatgtc gataaaatct ttattgatca aaaaggtgga
    44521 agtctcgtcc tgtatcctcg ggaaatttta tatattgaaa gtatcaaagg tttgaaaaac
    44581 caagttatgg tcaaaacaac tacagaagat aaattagtga atacttcttt aaaacaattg
    44641 aagacagagt tagaaaagta tgcttacttt ttacttttaa aatcttactg tatcaactta
    44701 tcgcaattgc agaaaattga ttctgctcat tatgtgttag aatttttcaa cggtgactcc
    44761 ttactcgttg gtcgaaagat ctttgaaaag acaaaggaac gtttccatga cttccaaaaa
    44821 actgcttcga gttgatgaat aagagctgag acgtaagcat agcagatttc agggagtggg
    44881 ccttgaatcg gctccactcc ctgaaatcgt tgatatgatt ttacgcttcc tcttctgtag
    44941 gagcatctgt taacgaccat gtgaatgttg aaacgtagtt gtctacagca taattggata
    45001 caggaacaaa taattccact gattgtctcc cttgttccac attctctcct aatgaataaa
    45061 tccatgtgcc aatcccttca tttgctcctg cagttactag atctactgcc tgatctgctg
    45121 ggatttcgat tccttcagcg ccagttccag aaacggtaga tggcattcca ctgctattag
    45181 ttgcgctatt tcgaatcacg gcgtttttga atttcacctt tgaaccagtt agtttattcg
    45241 tatcagatgt tgtaccaata aattctgttc gtttgactga taatttccaa ccggcataat
    45301 ttccgctttt atccgttact tgtacgaaat tctgtacttg tgtttgtgct ccagtactgt
    45361 ccgttccgct ttgtaatgca gcatatactg tttttgctgt acctaacttg attgttccaa
    45421 aatcaagatc tggagcttgg tcaatcgtca gtaatccgga tgttccctga tttggttcgt
    45481 caggtgtaaa aggagtatca ggatcatttg gatcaacagg aggaactgga acaacgtctt
    45541 caggatttgc agcatctggt ttggtcacag aaatcgttcc ttctgtagtg gctgagctct
    45601 tattctcagc aaaaacactt tgtgtacata ataatagact tccagctaga acggtactta
    45661 atgcaattgt ttttttcatt tctttttcct tctttctttt aaaataaata atccagcaaa
    45721 taagccaata agaatgactc caacaagtat cagccatcgc cagtcaaatg tttctggctg
    45781 attttttaaa tcaatatcct tttcattcaa ttggtccgct gcatcatcag ttatttcaaa
    45841 atcggtatgg agattccagc gtttttcttt ccaagcaccc ttcacaaccg cttgataatg
    45901 tcccggagct aatttttttc cttctaatgg gacaagtaaa tcaaaatttg tattgggtgc
    45961 tacatctatt ttttcttttt ttattgaaag gtaaggctct tttgtttctt ttttgtagat
    46021 ttcaaccgat gtagtcaagc cgaacatata agaagcattt ggattttgaa gattcgcctt
    46081 aatcacattt cttccatcgc tttgatccgc ataagctttt tttaatttca aatctgggga
    46141 agactctttt tcgctatttc aaatcaagat tgctttcact tgagaaaact gattgacgac
    46201 accaactgta cttttgttag aaacgttctc ttttttttct tgaaacgtga tccctcctgc
    46261 gaccacacca gccagctctt tttctggcgc tttcagtgaa agtgtctcag tgaccgcact
    46321 ttgaggagga acagttattt ctcccactgt ttttgctaag tttttcatat cataacttaa
    46381 tgtttcatca aatttacttt ttgattctcc atattcgatc acaccgtttg aattcgtcgt
    46441 agcggagtgg atcaatgtct caactgttac tgatttatct gttcggttaa agaccgtgta
    46501 ggggatttcc tgtgttttcc caggctccat ccttacattt atatatgttt tgttcttatc
    46561 aatctgatta gccggtaatt caaaatctac cgcaaaattg aattcggagg catggacagg
    46621 tgtctgccaa aggatgaatc caaggagaag gatcataagt aaagagcagt tgtttcgatg
    46681 acttttattc catattcgat tcatcaatca tcctccttga tctttattct gtcggcgcat
    46741 ctgctaatgt ccatgttatc tctgctgagt aattaccagc tatctgattt tctttggtta
    46801 agacaagttt aaacgcccga ccgttattta aatattctga ataatctgct tgcacattcg
    46861 ttgaattttg tcctctgaca atttccagtt cttcttcatt cactaattga tactcctctc
    46921 ctttcttgaa atataggaca tcctgcatag aaaatcctgc atcatttgtg aaaggctgag
    46981 ataattttat cgttaagatc cacggatttt tcgtttctcg ctgatcataa atccataatt
    47041 tttcctgtat atccatttgg ccaaatgctt cttgtgtcaa accagttgct ttgatctgac
    47101 caaaatcgag tttggaaggg gcaagaaatg agagaccacc ttctactacg atcttcgtag
    47161 caggtgcaaa aggcggggca tcatgataaa caactggcgt atcacttgga ttgtgattcc
    47221 caatttcatc gttggtactt ggcttgttct gcacaccctt agcagtagct tctcctgctt
    47281 ggtcgtttaa tacaatttct aatacatctc ctgcaaaaag ttgattttct gggatagaaa
    47341 gaacaaattc ccctgtatca tcaatagttg tttctgacaa aacagcttga ttttttttca
    47401 atgaaaccaa ggctcctgct tcacctgtac ctgtgatcgt gcgagaagct gcattgatca
    47461 atgtggtact taaattagca ggttcaggag gaatcacatc gactgtcgtt ttggcagagt
    47521 ccagttctgt cacttcttgg ccacctctta cttttttagc agcaacaact tgcacttgat
    47581 cctccgtttt taatctctca tcattgggta cttgaacttc gaacaagccg ccttgttcgc
    47641 cttctcccca tgggttatat cctgcccctt cattttcatc tgtttgtcct tgcgtgagag
    47701 cagtaatttc tacagatgat ttcgtcgtat ctgcgtaagt aatacgtaaa gtcacttcta
    47761 cttcgcctgt ccaagcatct cttggctttg cctcgacacc ttcgggaaca acgacatgcc
    47821 catagatttt tttatctgca ttcgttggca ctcttaagga ttcaatcatc gggagctgat
    47881 tattggcact gattcgatta taatttttca ttccggcacc tgtctgagca aattcatttg
    47941 ttaaacctgc actagggctt gatacgaaat tgcctaagtc ggtcccattg atcgataagt
    48001 ctgtcatatc agaaaaataa tccgggtctt tttcaaagtt atcgaatgtt gcgcctgttt
    48061 ttcgccataa agcgatttct gaatgggcga tctttaaaga agaatctcca tttccttgga
    48121 atacccagcc gcctatgcca ttggtctcgc ttccaatccg tttgttttgg aaatcaaaat
    48181 aggtaggaga ttctaagtcc acattcaaca catccccact gatgatgccg gtcttatctt
    48241 cccctgtttt cccgaccatg actaaataag ttttttcacc tgccgtaaaa tttaaatcaa
    48301 tatctccagt tgtatctaca gttgctccgg aatctgcgcg tatatcgata tttgattttt
    48361 ctccagtgac tgtaaaatca gctgaacctg gactttctag aaaaccagaa gcgtcataaa
    48421 attggatcgc ttgatttcct tgattgagtc tgttcacgta agatttgcca tcacctgtat
    48481 ttcttaccct caatgagcct ccattggtta ctgtcagctt ttgcgtacca ttctcaaaac
    48541 gaactgcgct ggaacgccca ctctgcttat cgatgtcgat aactgatccg gctccttcta
    48601 cgatcaaaga aaggcctttt cctacaaaac gcatcccatt gttcccgggt tgatcgtcat
    48661 ctccagccat tttgaccgag atttgtccac cacttgatac atggatttga ctagaatctc
    48721 cttgcaagcg aaatccgccc gtagttgctg tattgatggt gattttccca ccattcgata
    48781 cagtgacttt cgatcctgaa cctctcattt ggatgattcc gcgattgttg tcattggtaa
    48841 tattgatctt tgtatttacc gaaaattcgc ttcccgaacc actgacttca aacatgacat
    48901 taccaggtag cgtatcgact gcctctcctt catcgctaac gccatctgcc cgatcataat
    48961 caagagagac ctttgaaccg cttaagatat ggattcctgg cgctgttttt ccactaccag
    49021 tctcatctcc tgaatctaga aaaccgtaga atttccctag atacggtcca taaagttgac
    49081 taccattgat cacattcaat tgatagcttc tacaaaaata ggctttaccc ggagcggcat
    49141 tcagtccttc cttcactggt tggacatcca acacaccgga aacaccatct aatgtgacag
    49201 ttgcacgagg agcgtaaatc agtcctaatt tggacccatc atacaaatca agtgtcccgg
    49261 taaattttat ttctcccgta aaatgatatc tgcttcccca aaaatcggtc atataagcaa
    49321 tgataatggc atttccatcg atatttggtg tcaatccacc tggatgtgca gctgttcctt
    49381 taaaattctg gaactcgatc gactgaggta tctcattgat ataaatatgg tgtgtgccga
    49441 aattgtgagc gaatccacca aaatcaataa cgatatctcg tttgatctct aattccctgt
    49501 ctaaagtcaa aggctgaatc agtcggatct tagttactga ttcgtctgcg agaagctgcg
    49561 ccagttcttc tgttgtggca gcttcgctgt acccatccgc tgaaacagct cttgccagtg
    49621 ccgcttcact gctatcagac gtttgttcag ctacttctga ggtctcactt gtcttatttt
    49681 cttcttgcct tttattagta gaagcctcac tttgagattc tgtagtttca gaagtaatcg
    49741 attcttctga aaaagtagtc ttgtcaaaac tttgattctc tgattgcgtt gattcgtttg
    49801 ttttctctac atcggcaaaa acggatgtca ccatcaagag agggaagaca aacaaaatcg
    49861 acgcaatcag cttttttaca cattgattca ttctccacca tcctctctga cgttttgaca
    49921 attttatttt atcgttttaa tctatttcca attgtacttt catatttaaa atatgtattt
    49981 ttatggaaaa atttttctat taggtgtaaa tttctttttt gtacaaaaaa aaggctgtga
    50041 caaaagtctt gtcacagtcc cttatcccga acaagcggtg ttctcccgcc aactcctcgg
    50101 tcacaacctc cattttaaca ataaacctgt aaatgtgagg gcaatacttt gattgtcaca
    50161 ggtaatttat ccccttcatc tccatcaaca ttcgtcgtca attcttcctc atcagctaat
    50221 gacacaacta attgctcaca agtaaggtag gctagatttt tcgtagattc atctactcct
    50281 tttaataggt ctggcaatgt tttaagcgta tcgatcaaag aagaatcttt taaataaacc
    50341 aaatggagct taccatcatc cacttttgca tttggaagta atgtttcaaa accgccgact
    50401 gagttagtta gtcctatcag caaggtactg ctctcaattt cttccttctt tccatcaact
    50461 tctacgtgaa acgagtagga ttgtgtggaa gctaactgtt tgattcctga catgaaataa
    50521 gctagttttc caaatttcgt cttcttctcc gcatctacat cattgattga ttcagggata
    50581 gagccaattg cgacgacatt cataaaatag tcgtcattta tttttccaat atccaatggc
    50641 ttgactgatt caatcgaaaa atgattgatc gcttcctcag gttctagcgg tatccctaat
    50701 gctcgagcca agtcattcac cgtacccaat gggaaaaatc cgaaatttgg ccgatgttct
    50761 tgttcagcga ttccactgat tccttcgttg actgttccat ctccgcccat gacaaacaca
    50821 ctatgatacc cttccgtagc cgcttcgcga gtaaagtttt ttgcatcccc tgcttttttt
    50881 gtatgcaaga cgaccacttc atcaaacacc gattccaatt ttgctatcgc taattgctca
    50941 aattcctttg cttgttcacc gcctgaactg gggtttacca ctaataaaac ttttttcatc
    51001 actttctttc ccttctgatt gatttcttta atataacgat agcataaaga aaaaaattag
    51061 gctgtgatga agtactgttc atgaaacatt catttatttt ttgacaagat aaaacatcca
    51121 tactatgaaa ctgaggaaaa ttaaaacaat gatataggaa ataaaagaaa atgataggca
    51181 ttgtatacct aataaagtaa aaatcttagg tggcagataa aaacacaaaa atagcaagag
    51241 aatgtaatag cgtttcttcc actttttgtt atcagacctt atagcgatca gaggaatacc
    51301 aaatgcataa ctgaaaaact cttgatgtac tgttaatatg tcacggcctt gaataataaa
    51361 tgcgacaatc cccgctataa ttagtgtgcc taacaccaaa acggaaaatt gatgaatata
    51421 ttttatatac aaatgatcca ttgtacttcc tgccttttta tttgtgagaa aaacaaatcc
    51481 gtatacgtga ataacttcta gaaataaaag aaatttgcaa aaccactcca tttatctact
    51541 tctacgtgca ttttttgata ttgt
//
LOCUS       DAFLWC010000010        51257 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.010, whole genome shotgun sequence.
ACCESSION   DAFLWC010000010 DAFLWC010000000
VERSION     DAFLWC010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51257
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.010"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(56..1561)
                     /locus_tag="L1V17_000559"
     CDS             complement(56..1561)
                     /locus_tag="L1V17_000559"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HBN1235346.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLEFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(1653..2243)
                     /locus_tag="L1V17_000560"
     CDS             complement(1653..2243)
                     /locus_tag="L1V17_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBN1235347.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            2422..4068
                     /locus_tag="L1V17_000561"
     CDS             2422..4068
                     /locus_tag="L1V17_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBN1235348.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYFQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            4117..4836
                     /locus_tag="L1V17_000562"
     CDS             4117..4836
                     /locus_tag="L1V17_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBN1235349.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            5315..6262
                     /locus_tag="L1V17_000563"
     CDS             5315..6262
                     /locus_tag="L1V17_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1235350.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            6274..7194
                     /locus_tag="L1V17_000564"
     CDS             6274..7194
                     /locus_tag="L1V17_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1235351.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            7235..8692
                     /locus_tag="L1V17_000565"
     CDS             7235..8692
                     /locus_tag="L1V17_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1235352.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            9037..9651
                     /locus_tag="L1V17_000566"
     CDS             9037..9651
                     /locus_tag="L1V17_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBN1235353.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            9644..11368
                     /locus_tag="L1V17_000567"
     CDS             9644..11368
                     /locus_tag="L1V17_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBN1235354.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            11365..12816
                     /locus_tag="L1V17_000568"
     CDS             11365..12816
                     /locus_tag="L1V17_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1235355.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(13289..15442)
                     /locus_tag="L1V17_000569"
     CDS             complement(13289..15442)
                     /locus_tag="L1V17_000569"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HBN1235356.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDREYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(15444..16490)
                     /locus_tag="L1V17_000570"
     CDS             complement(15444..16490)
                     /locus_tag="L1V17_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1235357.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            16640..17929
                     /locus_tag="L1V17_000571"
     CDS             16640..17929
                     /locus_tag="L1V17_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HBN1235358.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            17942..20644
                     /locus_tag="L1V17_000572"
     CDS             17942..20644
                     /locus_tag="L1V17_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBN1235359.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            20629..21486
                     /locus_tag="L1V17_000573"
     CDS             20629..21486
                     /locus_tag="L1V17_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBN1235360.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(21557..22456)
                     /locus_tag="L1V17_000574"
     CDS             complement(21557..22456)
                     /locus_tag="L1V17_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBN1235361.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            22625..24796
                     /locus_tag="L1V17_000575"
     CDS             22625..24796
                     /locus_tag="L1V17_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBN1235362.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            24864..25205
                     /locus_tag="L1V17_000576"
     CDS             24864..25205
                     /locus_tag="L1V17_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBN1235363.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(25481..27235)
                     /locus_tag="L1V17_000577"
     CDS             complement(25481..27235)
                     /locus_tag="L1V17_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1235364.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(27246..28082)
                     /locus_tag="L1V17_000578"
     CDS             complement(27246..28082)
                     /locus_tag="L1V17_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBN1235365.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            complement(28084..28767)
                     /locus_tag="L1V17_000579"
     CDS             complement(28084..28767)
                     /locus_tag="L1V17_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HBN1235366.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            complement(28926..30320)
                     /gene="uxaC"
                     /locus_tag="L1V17_000580"
     CDS             complement(28926..30320)
                     /gene="uxaC"
                     /locus_tag="L1V17_000580"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBN1235367.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            complement(30359..31858)
                     /locus_tag="L1V17_000581"
     CDS             complement(30359..31858)
                     /locus_tag="L1V17_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HBN1235368.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            complement(31851..33272)
                     /locus_tag="L1V17_000582"
     CDS             complement(31851..33272)
                     /locus_tag="L1V17_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HBN1235369.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            complement(33332..34324)
                     /locus_tag="L1V17_000583"
     CDS             complement(33332..34324)
                     /locus_tag="L1V17_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1235370.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            34556..36754
                     /locus_tag="L1V17_000584"
     CDS             34556..36754
                     /locus_tag="L1V17_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1235371.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            complement(37212..38084)
                     /locus_tag="L1V17_000585"
     CDS             complement(37212..38084)
                     /locus_tag="L1V17_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1235372.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            38384..39358
                     /locus_tag="L1V17_000586"
     CDS             38384..39358
                     /locus_tag="L1V17_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1235373.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            39380..40072
                     /locus_tag="L1V17_000587"
     CDS             39380..40072
                     /locus_tag="L1V17_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBN1235374.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            40038..41546
                     /locus_tag="L1V17_000588"
     CDS             40038..41546
                     /locus_tag="L1V17_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBN1235375.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            41620..42723
                     /locus_tag="L1V17_000589"
     CDS             41620..42723
                     /locus_tag="L1V17_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBN1235376.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            42726..44063
                     /locus_tag="L1V17_000590"
     CDS             42726..44063
                     /locus_tag="L1V17_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBN1235377.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            44050..44928
                     /locus_tag="L1V17_000591"
     CDS             44050..44928
                     /locus_tag="L1V17_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HBN1235378.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            44925..45848
                     /locus_tag="L1V17_000592"
     CDS             44925..45848
                     /locus_tag="L1V17_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HBN1235379.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            45845..46255
                     /locus_tag="L1V17_000593"
     CDS             45845..46255
                     /locus_tag="L1V17_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HBN1235380.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            46259..47827
                     /locus_tag="L1V17_000594"
     CDS             46259..47827
                     /locus_tag="L1V17_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBN1235381.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            48067..49485
                     /locus_tag="L1V17_000595"
     CDS             48067..49485
                     /locus_tag="L1V17_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1235382.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            49497..50807
                     /locus_tag="L1V17_000596"
     CDS             49497..50807
                     /locus_tag="L1V17_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBN1235383.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
BASE COUNT        16518 a         9054 c        10466 g        15219 t
ORIGIN      
        1 aaatcacagt cccttttttt cttagaaatg ggaaaccact agtatataaa taccattatt
       61 cttcaatcaa ccgcttcacg attgcataat ccccttcata aggttcatct acaccattga
      121 ttttttgata gggatccacg ccttttcccg caataacgac tgaatcttgc ggagcgcttt
      181 ctgctaaagc gcgtcgaatc gcttcaggac gatccatttc ataatgaacg atcaaatctg
      241 gattagtaat tgcttcattg atttcttccg cgattttttt cggatcttca aatgctgggt
      301 catctgccgt caaaaaggcg atgtcagctg tttctgatag cacttttcca aaatcatgtc
      361 gacgggagat tgctttgttt cctgggctgc ctaatacaac aattacacgg ccatctggat
      421 gttcattttt ggcaaattcc agcaatgttt tcaagcttag ataattatgt gcatagtcca
      481 catagacatg cgctccattg gattggatca attgatccat tcggcctggt acacgagctt
      541 cttttaatcc gtcttgtgca tcttgactgg aggcacctgt tagtgctgcg gcaatgatcg
      601 cactggctgc attttcttgg ttgaatcctc cagccagcaa aatatcataa gcagtatcgc
      661 agatagctaa gcgatcttca tgagaagata aagtaaaacc gtgagtacct ttatctgaac
      721 ggatcacttg ataattgctt tcttccgaac gaccataagt gatcgttgga atctggaata
      781 gatcggctgt ttccctaagt aaatcaaaat agtcactttc atgatttaaa acaactgttt
      841 ttgaattcaa gatcaattgt cgcttgcaat agaaatagtc atcaaatgtc ggatgttcga
      901 tcggactgat atggtcaggc gagatattca agaagattcc gacatctaaa gtcaagccgt
      961 atacgcgttg tgttttgtaa gcttgtgaag aaacttccat cactagatga gtcataccat
     1021 tttcaactgc ttctgacatc atacgatata aatctaatga ctcaggcgtt gtcaaatggg
     1081 atttgaaata tgttttgcca tctaacgttg tattcatagt agaaagcaat gctgtttttt
     1141 tatttgttgt gtgatccaag attgcttttg taaagtacgc agcagttgtt ttaccttttg
     1201 ttccagtgaa tccgatcact ttcaatttat tttgcggata gtcgtaaaaa gccatagcaa
     1261 gaagcgccat tgctttacgg atatccgtta cgatgattcc tactgctgaa ttttcgtatg
     1321 gttgttctga tacataatat tgaataccct gttcgattgc tgaatccaaa tattcttctt
     1381 tgaaattcat tcctttacag aaaaacaaag tagaagcatc agcttttctt gaatcataac
     1441 ttaactgaag aaattcagct ttttctggta catcaagatg ccagcctctt gttgaaacaa
     1501 attcttttaa tagattttct tttaatagta aatgacggat gtcttctaaa gagaagctca
     1561 ttgattgatc cctcgcttta ttcaatttct tggtttatta tagcacactc tttttaatat
     1621 atcgtttgtt tccgctatga caaaatccag ctttattcaa attttcttga cacaggggac
     1681 aagcggatga gtattttcat aaacaatgaa ctgactgtaa tagataggag aacgaatagt
     1741 gtctccaaca atccaaaaac ataataattc aaaaagacga taagactatt ggtaagtaaa
     1801 agtccttgcg gcattggaag ccgaaaaaat ttgtggaaaa taatcggcgg tatcgttata
     1861 ccgccatttg aggccccgac tgtgtacaat gtgtaaaccc caagactgaa caaaagactt
     1921 cctgaaatca gtgaaaagaa atgtgaggag atcatttcca cttttggaac aatctctaaa
     1981 acaacaggaa aaagcagact tcccgctaca gtcttaaaaa atactgattt tcctaatagg
     2041 acagcggcta gaagcagcat cataagattg atgctccaaa cagtaactga gcgttggata
     2101 gaaaaggccg tttcaactaa atgtccgatg gcgcccactc cggcggaagc tatatcgtga
     2161 gggagcaaga accaattcaa tccaactgtg ataaagaaaa gacctaaaaa tataacgggt
     2221 agttttttta tttcttgtgt cattgatatc tcctataaat gttagccata aaaggctgta
     2281 tatttcttta ctttaccaaa aaaacgaaac cgaattcaaa aaaacaattg ttcttataaa
     2341 agttatataa aatcgattgc cagtttctgt tttaccaatt aaaatgatag taatgttttg
     2401 tagaaagttg gaatctgacc gatggataat caaagaaaac cagcattaga tcaattaaca
     2461 ccgcaagaaa aaatggcacg aggctctgct tggatgaccg ccagtaatat catttcaaga
     2521 ttgctaggcg ctgtctatat cattccctgg tatgcttgga tgggcgaaaa tgctaaggct
     2581 gccaatggat tattcaatat gggatacaat atatatgcat tgtttctact gatctctaca
     2641 gcaggaatac ctgctgcgat tgcaaaacaa actgcacgct ataattcatt gaatgaatat
     2701 ggcacttcac gacgattatt tatccgtgca ttacagatga tgggcgggct aggcctgttg
     2761 tttgctttgt tcatgtacat cgcctctcct tggctagctc atgcttctgg tggcggagaa
     2821 gaactgattc caacgatgcg ttctttgagt atcgctgtat tggtttttcc ttgtatgagt
     2881 gtgatacgag ggtattttca aggcaatcaa gaaatgatgc cttatgcgct gtcgcagatt
     2941 gtagaacagg tggcacgtat tttttatatg ctattggcta cattcatcat catgaaagtc
     3001 atggatggtg actatgtgac ggcggtcacg caatcaactt tcgcggcatt tatcggtatg
     3061 ctagcaagta ttcttgtcct tttgtatttt ttgaagaaac atcaagcgta tacatcggcg
     3121 tttattcact acagcgaaaa caaaataaat attgcaacga aggaattgtt gttagatacc
     3181 gttaaagaag cgattccgtt tattattgtg ggttcagggg taacgatctt caaattagtc
     3241 gatcagttca cttttatgaa gatcatgtct gcatccaccg agtattccaa tgcacagtta
     3301 ctggatcttt tttcgatttt tagtgccaat ccagataagt tgacgatggt agttattgca
     3361 ttggcaacat cgatcgcgtc tactgggtta ccgttgatta cagaagctgt tacgttgaaa
     3421 gatcgagtag gtctggcaaa attgacaagc ggaaatttac agttgttttc attttttatg
     3481 tttccggcga catttggtgt tatgttactt gcctatccgc taaatacatt attttataca
     3541 ccggattctc taggaagtaa tgtactgatc caagcaagtt ttgtaggact cttcctagga
     3601 ctatatatgc tagtttccaa catgctgcaa ggaatgtttg aaaacaaggc ggcaattaat
     3661 tatttggtta ttgggtttct agtgaaactc cttcttcaat acccagccat tcgtttattt
     3721 gaagtatacg gccctttatt ggcgacaatg atcggatttg ctgtgtcttg taccttgatc
     3781 ttaaagagaa tccatgaagt agcccgcttt aaaccaagtt ttgtctggcg caggacattg
     3841 ctgatcttta ttcttacctt gattatgctt ttggcttcgt ggatcacaaa gatgattttt
     3901 ggtgcttttt taaacgaaga tagcaaattc cagtctctat tgttgattct tgtagtagca
     3961 ggtatagggg ctttagtgta tggttattta gctttgaaaa tccgcttggc agaaagacta
     4021 ctaggaccag gaatagcgcg tttacgacat aaattaaaaa taaaataagt gaatcagaag
     4081 agctagattg atgctctttt gaaatggggg aaacgcatgc gtttagataa gtttttagca
     4141 gatatgggac ttggcagccg caaagaagtc aaaggattga tcaaaaaagg aacgatcgaa
     4201 gtcaatggac aagtggtgaa aagcgataaa gcgcaagtaa atgaattcga agatgcggtt
     4261 acttatttag gagaaatcat tacgtatcaa aaagattttt actacatttt gcataaacct
     4321 gcaggagtca tttctgctac tcaggataat catgatcaaa ccgtaatcga tttattggaa
     4381 gaccaggatt atcgggaaga tctttttcca gtcggccgat tagataaaga cacagagggc
     4441 ctcttgattt taacgaatga cggggtgttt gcccatcagt tactatcacc taaaaaacat
     4501 gtggagaaag aatatctagc tgaggttagc ggtataatga cagaagaaga tatccgttta
     4561 tttgcagaag gactgattat tgatggcgat gagcagacat tgccggcaaa actccaaatt
     4621 gatcaagtag atcaagagac agaaacttca attatccgtc tgattttgca tgaaggaaag
     4681 tttcaccaag ttaagcgaat ggtcaaagca gtaggaaaag aagtcttata tttaaaaaga
     4741 atccgtatgg gaaaattttg gctgcctaaa gatttgaata aagggcaata tcgacccatg
     4801 accaaagaag agctagaaca agtgagagaa aaataattga atggatagct aaaagaataa
     4861 gcagagtagt tgtagcgcca tctgaaaagc agacttgtcc gtctgacttt cggatggctt
     4921 ttttgtgaaa tttcggctta tttccgtaga agctacttct ggaacaccgt ttgttcggaa
     4981 taagggactg tgacaagact tttgttacag tccccattgt tccttgtgac tcagagttag
     5041 atagtaagga cacgatctcc ctaatactca ggccaaaacg ctgaattcac aacctctgat
     5101 aaacggtgtt caatcagctg accctcggta ttagctcaaa aaacggcaaa atatgaggaa
     5161 ctattttccc gtttttttct ctaatactca ggccaaaacg ctgatttcac aacctctcct
     5221 atactttgtt tcattttccc tatactttgt ttatttattc tcattattga aagcgctata
     5281 attacgttgc gaatgaatcg aaaggggttt ttagatgaaa aaacgaaagg ggttcaatca
     5341 tttttttatg aatctatggc gttataaagc acttgtcctg atggctgtac cgggtatgct
     5401 ttggatgatt tttttctttt acatacctgt aatggcgaat gtcgtagcat tcaaaaattt
     5461 tcatatttca gcagatgggt tcttggctag cttgagggaa agtccttggg tgggttggga
     5521 aaatttcaaa tttttatttt cttcggatca agcatttctc atcactaaaa atacaatttt
     5581 atataatgta gcatttatcc ttttgaatct gctgatctca gtcgtatttg caatcattat
     5641 gagcgagttg agaaataaac gactcgttaa agtttatcaa acgatgtcct tactacctta
     5701 ttttctatct tgggtcatta tcagttactt tgtttacgct tttttaagtc ctgacaaagg
     5761 aatattcaat cagtggatca ctggacatgg aggagaagct gtcaattggt ataatgaacc
     5821 gaaatattgg ccgtttatct tggtgttcat tggtacatgg aaagggattg gttataacag
     5881 cattatttac tttgcatctg ttatgggaat cgatccgact tattatgaag ctgctatggt
     5941 tgatggagct agcaaatggc agcagatcaa acatgtgacg ataccacaac ttattccact
     6001 aatgacgatt ttaacgattt tagccgtagg aaacattttc cgagctgatt ttggcctgtt
     6061 ttataacatt cctaggaatt ccggtgcatt atatgatgtg actcaagttt tggatacgta
     6121 tatctacaat ggcctgacat ccacaggaga ttttggtatg acggctgctg caggacttta
     6181 ccaatcagtt gtcggctttg tcttgttgat gatcacaaat acgatcgccc gacgttttga
     6241 tagcgattct gcattattct aaggaggaaa aaaatgaaaa aaaagaaagt ggagagagtc
     6301 caagtccgct ctttcaataa gacggctaat tttttctcta atataatgat tgcactcttt
     6361 gctatttcct gtattttgcc atttatattt gttatcgcca tctcttttac cgatgagtcc
     6421 atattgtcga ctcacgggta cagtttttgg ccagaaaagt tcagtatatt tggttatacg
     6481 tacttgttcg accagatgca ggataaaatt ttccaagcgc ttttcgtcac tgtacttgtt
     6541 actgttttag gtacactgat caatagcacg gctacttctt tatatgctta tgcgatttca
     6601 cggtcaaact ttccattccg tcgttttttt accgtttttt gtttgattac gatgttgttc
     6661 tcaccaggga tggtggccaa ttatcttgtt atgacaaatc ttcttcagtt aaaagatacg
     6721 atttgggcat tgatcttgcc aatggctgtc agtcccttca atattattgt gatgcgcaca
     6781 ttctttaaac gttcggtctc tgattcgatt attgaatcgg cacggatcga tggagctagc
     6841 gaactgcgaa tatttgttca gatcgtttta ccgttagctg ttccaggtat tgcgacaatc
     6901 agtttatttg ccgcattggg ttactggaat gactggttca atgctttact atacatccaa
     6961 gatgataagc tagttccact acagtatctt ttgatgaaaa tccaaagtaa tattcaatat
     7021 ctgacacaaa attcaggagc aggaagccaa ttgacaggcg gattagcctc agttccagga
     7081 gaatctgcca gaatggcgat cgtagtcatc tcgacgttgc ctattgcgat cagctatcca
     7141 tttttccaga agcattttgt caaaggtcta acaatcggcg gagtaaaaga ataaagaaac
     7201 aaaaatataa atcataaaat taggaggaag aaaaatgaag ttatggaaga aactagcctt
     7261 tacaggtgtt tcagcgttgt tgttgggaac attagcagca tgcggaggtt ctggttctaa
     7321 agaccaggca gaagctagca attcggacac tttgcagatg tatcaaatcg gagataaacc
     7381 agataatttc gatcaattga tggaagtagc aaacaaacga atcgaaaaag agatcggtgt
     7441 aaaagtcaat atcaattaca ttggctgggg cgattacgaa aagaaaatga acgtcatcat
     7501 ttcttccggg gaaaattatg atatcgcctt tgcgaacaac tatgtttcca atgcccaaaa
     7561 aggagccttt gctgatttga ctgaattagc gcctaagtac gctgaaaaag cttataatga
     7621 tttagatgaa gcatatatta aaggaaatct ggtcaatgga aaattatatg ctttcccagt
     7681 caatggaaat gtctttgctc aacaagtact tacttttaac aaagctttac tagataaata
     7741 cgatctttca attgatggaa tccaatctta cgctgatgca gaaaaagtct tgaaggaatt
     7801 ccatgaaaaa gaaccaaaca cggcagcttt tgccattgga caaggcttca aagtccaagg
     7861 gaactttgat tatcctttag ggaatacgtt accatttgct attgatctgg atggagatga
     7921 ttcgaaaatc atcaaccaat acgataatga aacgtatatc ggactgttac gtacaatgca
     7981 tagctggtac aaacaaggac tcattccaag tgacgctgca acgagcaata aggattatcc
     8041 actagaagga aatacttggc taatgcgtgg agaaacacaa ggaccgtatg attatggcga
     8101 tacaattttg acaaatgcag caaaacaaga acttgtctca aaagcaatta ctgttccact
     8161 aaaatctaca gctcaagcac aaatggcaaa ttttgtcgta tcaaatactt caaaaaataa
     8221 agaaaaatca gtagaacttc tagggctgct taacagtgat ccagaattat tgaatgggct
     8281 tgtttggggg atcgagggag aagcatggga aaaagtcgat ggttcagatg ataaaatcaa
     8341 attgctagat ggttatcagc caaatacaca tatgtctgct tggaatacag gaaacaacaa
     8401 gattctatat acacaagagt ctattacgga tgacatgatt gccaaacgtg atcaatcgat
     8461 tgctgatgca gaaacttcac cgattttagg attcagcttc aacactgaca gtgtcaaaac
     8521 agaattaagt aatatttcta atgtcatgaa tcaatattta gatggattga atacagggac
     8581 tgttgatcca gatgaaacat taccgaaatt gaaagacgct ttggacaagg ctggctatga
     8641 taaggtattg aaagaaatgc aaaaacaata tgatgagttc cgacaagaat aataatgaat
     8701 aaagacaaag gggttgtgac aaaagacgtg tcacaacctc ttgttccgaa taaacggtgt
     8761 tcaaaagcca gtttctcggt attaagctaa atatatgtaa aaatgtggaa agccatattc
     8821 acaaaatttt tcttactact cgaaactaag cggctatttc acaaactctt ggtaaacggt
     8881 gttcaatcag ctaaccctcg gtattcgctc acaaaacgac aaaatatgag gaactatttt
     8941 tccgtttgtt tctctaataa tcaggtcaag gtgctgattg cccaaccttt ttttgtataa
     9001 tgagaaagta taaacttaat gtttggagga gaagatatgt tagggaaggt tttggaagag
     9061 ttatttatcc ggatctgggt cattataaaa ctaaccttgt atttctggat atatacattt
     9121 gccggcggga tcatctttgg attaggtgcg gcatggaaaa cagtcaatga actattttat
     9181 ttgtacggat tcgagtataa agaaatcaca ataaaaagag gctggaatat atataaaaga
     9241 aattttttaa gaggcaatct gctatttagt ttatttttat ctggtactgc tttattgagt
     9301 tacaatttat atttatctgt tcaaatcaaa gggctcattt ttttagctat tgattttatt
     9361 ttactttttg ccttgctctg cctatttgct acttatcaat acagtatgat tttagatagt
     9421 gaatatacga tctctgttcc taatctgcta aagctaagtt ttatttcggt tttttccagc
     9481 ttttcgtctt ttctaaaaat aattattggt agcggtataa ttttaggcgt gacttggcaa
     9541 ttcaaaggat tgatcctgtt tggtgtcatt ggtcttttga cggtttggaa tggtacgatg
     9601 acaacacatt ggcgtgaaga attagataaa cagttggaaa gttatgaata agtttcggat
     9661 tctattttca aaaggaacct tactaaatcg tctgttgcgg aaatacgcgg ttatcatgat
     9721 cggtgtaacg atgactgcta ccgttatttt tagtatccat acttgggaac aaaatcaaaa
     9781 acaggcagaa aacatgacaa gtgatgccgt tcaaagcaca agcagaatgc tgaatgataa
     9841 aacaaccttg agtaggatca tcaaaaacca gcttgtaggg aattccgaaa agatcgaaaa
     9901 tgtgacgacc tacttaacaa aacccataga tcagtatctg atgtatgtat acgaacagca
     9961 aaacagtacc gatgaattag tttctttccc aaatcaaatc aaagatctct acgcaaatta
    10021 tgaagaacta agtgcgatat atatcgtgtt gaatcaacta ccggagtatt atgaatcttc
    10081 tagagaaaac aaaggtgggg aaataaaaaa ggggacacca aaattactag acgcctttta
    10141 tatcaagttg cctatcacac aaggaggagc tgagtcagga agtattttta ttggttttca
    10201 aaagaaagaa ctagatatga ttttagaaaa tctaacgtca ttcaatggac tctctttata
    10261 catgatttct ggaacgacaa atcgactata cacattccat gataataaaa tagctaaaga
    10321 aacgtttgaa agacaagaaa tgatcatcac agagagtctg aagaaaaatt cacaattgcc
    10381 gattgacgat ctggaaaaaa acaattttgt tcaacaccaa gaactgtctg atgattatcg
    10441 tatattagct gtactagata aaaaaagtgt aaaaatcgaa acgggaaaaa atcttgcccc
    10501 gctgatcatt ggtatcatta ttttagacaa tatactgctt atctttcttt ataaaacatt
    10561 caaacgatat tcacagcaag tatctatcgt catgcaggcc atggatcaaa cagcagcagg
    10621 gaatttagag acgcggatcg acataacaaa cacggaatat gaactgaagg aactttcaat
    10681 cggtatcaac gaaatgttgg atagcatcaa tcagtttgta gaagacatct acaaattaga
    10741 aatcaaacag caagacgcac atatgcgggc gcttcaagca cagatcaatc cacacttttt
    10801 atataataca ttagaatata tccgaatgta tgcaatcagc gaaggaagtg aagaattagc
    10861 agatgttgtg tatgcgtttt ccgctttgct tcgaaacaat acgaatcaag agaaaacgat
    10921 cactttaaaa gaagaactgg acttttgcga aaaatatgtc tatttgtatc aaatgcgtta
    10981 tcctaatcga gtagcctatc attttatgat cgatcctgat ttggaaaaga tcgaagtacc
    11041 taaatttgtg atccagccat tagttgaaaa ttattttaaa cacggtattg attttactcg
    11101 attcgataat gcgctaagtg tcaaagtctt gcaggaaggc aaacgggtaa ggatcatcat
    11161 caaagataat ggaaaaggga tgactgaaaa acggctaaaa cagattgaag aaaaactgtc
    11221 tcatcctaaa gtggaacttc acggttctat cggtctgcaa aacgtgaatg aacgtttacg
    11281 tgccagcttc ggcagcagtt attatatgtc gcttgagaat aatgagacag gtggactgac
    11341 cgtttctatt acattcaagg agggatgagc gtgtatcaag tgttattggt agatgatgaa
    11401 tacatgattt tgaatgggtt aaaaaagata attgattggc aaagtttagg ctttcaaata
    11461 gtagcaacag cagagaatgc caaagaagga ctagctgtac ttgaacagcg acagattgat
    11521 ttagtagtaa cggatgtgac aatgccagaa ataaatggac tggaatttat tgaagcggct
    11581 caaaaagaac gtcataattt tgaatttatg attttatcag gataccaaga attcgattat
    11641 ttgaaaggag gtatgcaatt aggcgccgtg aattatttga tgaaacccgt gaataagttc
    11701 gaattggttg aaagcctcaa gaaaatcaaa acacggttag atcagcaaaa tgaacaaaaa
    11761 aatcaacaag aaatctatca agaactgtta ttcagtcaat ggttgaatga agaattggat
    11821 gaaataagtg aagaagaaat aataggacaa ataagtgaga agcagcatag gatagtattg
    11881 attcaactgg caagaactca tgatactctt atcaatagat ggttgcaaga acggcaacaa
    11941 atcttttact atcaacgaaa ttacggagac cgtgtattga tcacgttgtt gttggaggca
    12001 gatgaagttg atggcttctg ttgttttgtt caagaaaact ttcctgatca ggaatggctg
    12061 atcagtatcg gggaagagac agattctttg gacaaaatcc ctgaaacatt ccaacaagcg
    12121 aaagacaatc tacagttgca tcaattttat ggagataaag acgagcatgt tttttacgca
    12181 gtacaagcag aaacaaaaga tcaaaccatc gatttttcaa gtttcagacg cgtgctgcaa
    12241 aataaacaat tggaagtcgc tcaaaaaatg atcactgatt tttttgaaca gtttcagtta
    12301 gcagccatga tgccggaaga tatacgatat tccagttttt tactgtttat ggagattcaa
    12361 cgggaattga ttgatctgga agatgaggaa tatttacaag gaatcgaaaa aatccatcag
    12421 gcaaaaacgg tgcaagaact tcagcagcta cttctgtcat tcatcaaaaa gcatcagaga
    12481 cagaaaaagt acagtgacaa tgtggaaaaa gtaatcgtaa tcctgcacca gcattatcaa
    12541 gaaccactta cactcaaaga agtgtcagaa aacctgcatt taaatgtcat gtatctagga
    12601 cagctgttca aaaaagaaac gaaaaaaagt ttttcagctt atttgaacca tttacgtatg
    12661 gaaaaagcga aacaactgct tttgcacagt aatcaaaaca tcaatgagat agcaagtgag
    12721 attggctaca acaacaccac gtatttctct aaattattca agaaaatcgt cggcagatcc
    12781 cctaaagagt accgagaaaa cagtggagaa tcataaaaaa aaaagccaat gtaatgaaat
    12841 aacttataaa aaattgtcta gaaatctaat tttgggctgt tcttattact tgaggcaagg
    12901 cagctttttc atgacctctc gataaacgga gttcaaaagc cagtttctcg gtattaagcc
    12961 aaatttatgc aaaaatgtgg aaagccattt tcacaaaatt tttcttaata ctcgaaacta
    13021 aacagctttt tcacgacctc tccactaaat ggtgttcaat cagctgaccc tcggtattag
    13081 ctcaaaaaat ggcaaaatat gaggaactat tttgccattt gtctctctaa tactcaggtc
    13141 agaacgctga tttcacaacc tctcaataaa cggtgttcaa aagcttgcat ctgcggtaat
    13201 aagaccaacc aaacgaaaaa tatgaggatc tatttttgct tggctgttct tattacttga
    13261 tgcaggacag ctttttcaca acctcttgtt aattatagtt tgataaggaa aaaggcaaat
    13321 cttttgcttg atatttctta gggtgaggga tgatccctaa ttggtaagag atcgtgccgc
    13381 ctttcagcaa atcttgatgg gtaaaatata atttcgtata ttctctgtcc atccgtttga
    13441 ttttatggat aaattgttgc tgcggccgat taggcgttgc ttcaatcgtc aattcctttc
    13501 catttgacaa aagcaaaaca gccttgtcaa ttaatggcat accgataaca tattcaccgg
    13561 ttccaggcgt gacaggataa aatcccagac tattgaagat ataccaagcg gccatacttc
    13621 cattgtcctc atctccaggg taacccattg gagaatcgtc gaaggtctga gtcatcaact
    13681 gtttaagcag tggctgtgcc atttcaggtt gtcctatata actgaacaag taaggatagt
    13741 gaaaacttgg ctggtttgaa atagctaatt gtccaaattc tatcgcggcc atctcactca
    13801 tttcgtggat ctcaaaacca tatcctcctg ggtcaaacgt tgggggctga ttgcacagct
    13861 caatgagttt ttctttatat ctctcactgc caccatattt tccgatcagt cctgaaaaat
    13921 cgtgataaac agcaaagctg ctttgccaag cacttccttc tgcataatct tgtccccaac
    13981 gattagctga aaatggttct ctgaacttgc catctttatc ttttgaacgc ataaatcctg
    14041 actcatagtc aaagatattt tgatagttca atgattgctg ctgatatttc ttcgtcattt
    14101 cctcttcttc tagtaccttg gcaacttggc taatacaaaa atcgctataa gcatagtcta
    14161 atgtgtgatt gactgattcg tggtagtgat taggaacata gccatatgtc aagtaatctt
    14221 ctgttccttg gcgtccataa tttggatgtt tgctttgaac cgtagcacct ttttccattg
    14281 ccgttagaaa ttcaggcatc aagtctcgtc ggatatcttt tacagcagca tctgcaatga
    14341 ccgcatcgat caatgtccca ggcataagtc cacgttcatc aggagacagc cattttggca
    14401 aatagccact ttctctatag ctgttcaaaa aaccttccag catttcttcg tatttttcta
    14461 cagcaatcaa agaataaaga ggataaaccg ttttatacgt atcccaaaac ccattatttg
    14521 tatagagaac accaggtttt atagatcgac tagtcgtatc atagtggatt ttttgcccac
    14581 taggatcaat ttcataaaat gtttgtggaa ataaaaacac ccgatataaa ttatgataaa
    14641 acgtccgcaa ttgttgttga tcatggtgtg tgagctgtat acgatcaaaa taggactgcc
    14701 attgttcttg actgtgagca aggtaagtct ctttgctttg gttttgttct agttccaggt
    14761 tataagctgc ttgttccgag ctgataaaag atgtcccaaa tcggatagtt tgtttttttg
    14821 tctgttcaaa atacaacggg atcgagtcgc tatttttgtt ggaaacagct aactcatcaa
    14881 ttgttaaagg atattcaaat ctcaatataa aataaaaaga aaaatcagga tcttctgaac
    14941 cagcaaaatg tgtgattttt ccttccactg tgtaaggatc tataacaaag agctgatggc
    15001 gtcccggaaa ggataaaagt aaaccgctgt catttttgct gtaatcaata gataagattc
    15061 cgccatacat gctaggtatc aatgtagaac agatgccata acgtaattga cagatcgaca
    15121 gatgagtcgg gcaaaatata ctttcttctg ggcggtaaga actttgagca tggaaaaggg
    15181 tgttctcctg tagttttcca ttgatcggcg taaacagcat atgactgaaa tcacccatcc
    15241 aaggacttgg ttgatgggta agacggtagc cttgaaaaac gcggtcatca ggatgaaacc
    15301 accagctgcc gttttgatcc gtagtttgcg gtgcaaaata attcatccca aaaggaacgc
    15361 cagtataagg ctggcagttc ccattagaga aatttggctg attcgctgtt gcatgtctag
    15421 tatctatttg accgatattc attttatttc tcctttgttg attgtctttt gatgaatgaa
    15481 actggaaatt tactatcgga tggtcgatct tttgtctcta accaagtgac caaagcatct
    15541 cccgcaagct tacctaactg ttcaaaatct tgtgcgatgg ttgtcagtgg cgggtcaaca
    15601 agagctgctg cttggatatc atcaaatccg ataattgaaa aatcttcagg gatatgataa
    15661 ccatgctgtc tcaagagatt catggtctgg atagcgacaa catcgttttc acaaacaaaa
    15721 gcagttactt catacttagt gatataagaa agcaattcat ctaatgtcgc gcttttgtca
    15781 tccagtgaag tgtggaaagt caaaccagct ttgtccaatg cttcaaggta accaaggtaa
    15841 cgctgtcgaa cggattgtgg atgagtctgc gtaccaaaca aataagcgat ttttgaatgt
    15901 ccctgttcga tcaaataaga ggcagcaagc gcaccgcctt ggaaattatc ggaaagaacg
    15961 gtaggaaaag gtaactcata gattttttta tctaatatga cgacagggaa ttctttcaat
    16021 gaaagctcaa aaagtaagtc aagatgttgt tctgtatcaa gagcataata aatcaatccg
    16081 tcaaattcat tgattagctc ttttgctgtt ttattttgta gaaagtcaag cgtcgtcatc
    16141 atgacatcaa tctgtttatc ttgcatcaca gggttcaatc ccttgctaaa atcaccaaca
    16201 gacaaatcag cgacatatgg aagaagaaac agaatccgtc gtgtttttgt aggagaagca
    16261 agaatctgtt ccggagaagc ggatttaacg aaactgcctt tcccgcgaac gcgataaata
    16321 agtcctaatt gctctaattc agtcaatgca cgtttggaag tgattctgct tactttatag
    16381 gtacgtgaaa gttctttttc agttggtagt tggctgtcta caggtaattc accagttaaa
    16441 atagccgttt gcaaatcatt aaatattgtc tggtacaatg gttgagtcat ataaacacct
    16501 cttaatgata tatcatattc aaataatacc ataatggatg aaaaagtaaa taaaaagata
    16561 ttttttgaaa gcgtagacat aattggctgt atgaagtata atctttaaag atatatcaaa
    16621 tagaaagaag gttttattag tggtttataa agatatacca aaatcggtgc agaaatttat
    16681 ggaagatatc acacaaaaat gtggggatat ccatgcggac tgggcaaaga attttacagc
    16741 agcatttgcc aatactctgt tgacaacagt caaaaagcaa aatgacggaa ccaccttttt
    16801 attgacggga gacattccag cgatgtggtt aagagactct actgcacaag ttcgtcctta
    16861 tttagtgatt gcaaaagaag atgaggaatt agctgacatg atcagcgggt tagtcaaaaa
    16921 gcaatttttt tatatcaata tcgatccata tgcgaatgcc ttcaacgaag aagctaacgg
    16981 tgctggccac caaacagatc atacaaaaat gaacgattgg atctgggaaa gaaaatatga
    17041 aattgattct ttatgctacc caatacagtt ggcctatctt ctttacaaaa atacaggaaa
    17101 aactgatcaa ttcaatcaat cttttattga aggtatcaaa aaaatcttgg acgtgttcaa
    17161 aacagagcaa gatcatgaac actctcctta tacatttgta cgagacacga caagaaaaga
    17221 agatacgctg atcaatgacg ggcgaggtgc aaaaacagct tttacaggaa tgacatggtc
    17281 tggtttccgt cctagcgatg atgcttgccg ttatggatat ctggtaccat ccaatatgtt
    17341 tgcggtggtc gtgttaggtt atgtggaaga aatttttcaa acgatactcg atgataaaga
    17401 aattgtacag caaacacaga aattgaagaa agagatccaa gaggggattc agaatcacgg
    17461 acgaacggtt aatcaaaaag ggcaaacgat ttatgcatat gaagtagatg gaatgggaaa
    17521 cgccacagtc atggatgaca gtaatgtgcc caatctgatc gccgcacctt acttgggata
    17581 ttgttctgaa caagaggaag attatctgca aacaagaaga acattgttga gtaaagaaaa
    17641 tccatatttc tatgaaggaa agtacgcaaa aggaattgga tcctcccata cgccagaaaa
    17701 atacgtttgg ccgattgcat tagctatgga aggaatgaca acgtcagaca aatctgaaaa
    17761 agagcggata ttgaatttac ttgtagcaac tgacgcagga acacacctta tgcacgaagg
    17821 attcgatgtg aacaatcctg aaaattatac gagagaatgg ttttcttggg caaatatgat
    17881 gttttgcgaa ttagtcatgg attactttga tattagagta gaaaagtagg aggtatcgta
    17941 aatgaaaaag aaagtatata tcatttctca tagccactgg gatcgtgaat ggtacatggc
    18001 ttacgaacag catcacatgc gactgattga attgatagac gatctactag agctatttga
    18061 agttgatccg tccttcaaca gttttcattt ggatgggcaa acgattattt tagatgacta
    18121 tcttcaagta aggccagaaa aaagacaggc aatccaacaa gcaatcaatg aaggaaaatt
    18181 gagaattgga ccattttata tcttgcaaga tgattttctt atcagctcgg aatcgaacgt
    18241 gagaaatatg ctgattggca tggaagaaag ccgtaaatgg ggaacccctg tcatgttagg
    18301 ctattttccc gatacatttg gaaatatggg acagacgcct caattaatga aacaagctgg
    18361 tatttcagca gcagcgtttg gccgtggtgt aaaaccaatt ggctttgata atcaagtttt
    18421 ggaagcagaa aactattctt cccaatactc agagatgtgg tggaaaggcc ctgatcaaac
    18481 agcaatcttt ggtctgctat ttgccaattg gtatagcaac gggaatgaga ttccagtaga
    18541 aaaagaagca gctcttgcct tttggaagca aaaattagcg gatgcagaac aatatgcctc
    18601 tacgaaccac ttattgatga tgaatggtgt tgatcatcaa ccggtacaaa aagatatatc
    18661 aaaagcaatc catctcgcaa atgaactgtt tccagattac gagtttattc attctaattt
    18721 tactgactat ctggaagcag ttcaaaaaga tgtgccagaa gacttaggct cagtagaagg
    18781 agaattgaca agtcaagaaa cggatggctg gtatacttta gccaatacag catctgctcg
    18841 ggtttactta aaacaatgga ataccaaggt ccagcgacag ctagaaaata ttacagaacc
    18901 acttgcgacg atggcttatg aagttagtgg aaactatccc catgatcaat tagattatgc
    18961 ttggaagaca ttaatgcaaa atcatcctca cgacagtatt tgcggttgtt cagtcgattc
    19021 tgtccatcgg gaaatgatac ctcgttttga aaaagcagat gaagttggaa agtatcttgc
    19081 acaagattcc ttagaacagc tgaccgcagc aatcgatacg accggattcc caaaagacag
    19141 ctttccattt gtcattgtaa atactgcagg aatggataaa actggtgaag cagaaataac
    19201 catcgaatta gaaagaaaaa gattcgctga aggaatacct gaacaactat atcaagagtt
    19261 agaaaatttg cctaaacgta agtatcatgt agaaacaaaa agtggggcca ctataccagc
    19321 tattttatct gaagaaactg tccaatttgg ttatgatttg ccgaaagacc gtttccgtgt
    19381 gccatatatg gcaagaatga tcaaagtgac tttaccatta gaaaacatgc cagcattttc
    19441 ttgggaaaca ttcgcgcttg tagaagggga agcgaaagca gaagaaaagg aaacaatgat
    19501 tcatcagagt ggacgaatca tcgaaaacgg ccctctacat ttgacgattg aaaaaaatgg
    19561 taccattaca atggaagatc gcaaaaacaa acgaaagttg aataatctgc atatttttga
    19621 agatatcggc gatataggaa atgagtatat ctttaaacaa cctttctgtg atcagccaat
    19681 cctatccagt aacaaagaaa actctgaagt aaaagtatta gtagatacac cggaaatagc
    19741 aaaaataagt attctacagg aaatggaaat ccctgtttct gcagacgagc gtttagaaaa
    19801 agaacagcag atggttgtgg aatttcgtta tcgaaaagca gaacgatcca aagaaaaacg
    19861 aatccttcaa ataaaaacaa tcatgacaat cagaaaagat agtaaaaaaa tcgactttga
    19921 aacgactctc gacaatcaga tgaaagatca tcgcttacgt gtcttgtttc ctacaaagtt
    19981 acatgtggaa catcacgaag cagatagtat ttttgaagtg gtgaagcgcc caaaccatgt
    20041 gtctaaaagt tgggaaaacc ccacgaatcc gcaacatcag caagcatttg tcaatattca
    20101 tgatgaagag tacggtgtaa cagtcggaaa ctttggtttg aatgaatatg aagtaacaga
    20161 agacggacaa atcgcagtga cgctacttcg cagtgtggga gaactaggcg attggggata
    20221 ttttccaaca ccagaagcac agtgtctagg tgagcatcgg ttcaattaca gcattgaact
    20281 acatggacca gaagaaaaat tctctactta tttgcatgca tacgcagcac agattccttt
    20341 ttccactcaa caaatcaaac atcatgaagg aacattgatt tcaaaacaac aatatttaac
    20401 gataaaaagt gaaacgtttg caattacagc tttgaaacgc agcaagttta gtgataaagt
    20461 agtagtaaga ggtttcaata tgtctagtca tttagaaaaa ttggaaataa ctaaagacaa
    20521 tggaaaaact gtcatattga atctgcttga agaaccaacg aagcaagcgg ttgtcccaat
    20581 aatccaacct tatgagattc ggacaatcgg attcgaggag gaaaacgaat gtatggcgga
    20641 atagaagcag gcggaacaaa atttgtgtgt gcggtttcag atggtggaga aattttagaa
    20701 aaattaagta tccctaccac aacaccagaa gaaacattgg atcaggtatt tgaatttttt
    20761 gatcgttatg aattgaaggg aatcgggatt ggctcattcg gcccgattgg tatcgacaaa
    20821 acaaaagata attacggata cgttttggca actcccaaaa aagggtgggc acaattcgat
    20881 tttcttggca caatcaagga acgctacaat attcctgctg cttggacaac ggatgtcaat
    20941 gctgctgcat atggggaatt gaagcaagga gcagcacaag gaaaaaatag ttgtatttac
    21001 cttaccgtgg gaacaggaat cggtgcaggt gtcgtgatca atgaagaaat tttttcaggg
    21061 atcgcacatc ctgaaatggg acatatttgg gtgaaacgcc atccagatga ccattatgaa
    21121 ggtacttgtc cttatcataa agattgttta gaaggattag cagcaggacc gtctattgag
    21181 gcacgcacag ggatcaaagg gcaagatctg ccgcaagatc atcctgtttg ggctattcag
    21241 gcttattata ttgctcaagc actgatcaac tatacgttga cgttagcacc tgaaaagatt
    21301 attttaggcg gtggggtaat gaatcaggat catctccttc aaaaaatccg tcagcaattt
    21361 gttgaattga tgggtggtta tatggaaaca cctcaagtaa gtgaatatat cgttcgttgg
    21421 ggactgccga atgaaagtgg gattatcggt agtttgctgt tagcagaaca cgaacatcaa
    21481 aagtaagcag acaaattaca caaaaagaac agagtcttat cattatctgc tgataagact
    21541 ctgttctttt ttatttctat tcccataatc caggtaaagc tttaccgact attttttctt
    21601 gagtaaatgg atggatcatg tgcagttcta atgcatggag catcagtcgt tcagctgttc
    21661 tattttggta gagagggtct ccaacgatcg gatgtccctt atgagctaaa tgaactctga
    21721 tctggtgtgt acgtccggtt tccaaaacac aatagacttg tgtttgttca gaaagtactt
    21781 tgttgacagt gacatgtgtc aaggcgctct gaccattttt atcatctacg accctttttc
    21841 tccgatcatg gcgatctcgt ccaattttat tggtgatggt catatctttg gcaatttctc
    21901 cccatacgat ggcttgatat ctccgataga tcattttttg ttccaacatt cttccaagta
    21961 tcggcaagac aaatggattt tttgcaaata aaacggcacc gcttgtttct ttgtccaagc
    22021 ggtggacaac gtaaggtcgt tgctgtttag tgtcgagata agcagctaaa tgattgagta
    22081 aggtactgtt ttctgtcggt tcatttggat gagtcttcat tcctgcaggc ttatccacta
    22141 taatcaaatg ctcatcttca tataaaacac ggatgtgctt cgcatctcct aattgaactt
    22201 cttgataatt ataatctgtt tcttcgaata acaatgtgat ctggtcattg ccctttactt
    22261 catgatggaa caaagcaggt tgttgattga tccaaacgtt tttacgtata cgcaaaaagt
    22321 gtcgaacctt tctaggaact aaccattcct tttcaagcaa gtcgcgaatt gttgtttcag
    22381 gatggttcat aggtaaagtg atcgtgattt tcacaagtgt actcctttca gtgcaatcgc
    22441 agactaattg taccattttt aaaacatatt taagaaaaaa cttacatttt tctgttcatt
    22501 cttatgttac tctacttgca ctaacgtaaa aaaacatatt gaactacaac ttaagcagga
    22561 agaaaacact ctttcactat ggtaaaataa gacgattgaa tcaaatagac aggagaagaa
    22621 gcaaatggat tttcaaagca ttttagaaaa gataaaagct gctttgatca gtttttggcg
    22681 ttggatcaga ccatatctcg gacaattcca tcgatggcga aagcgcatct ggaaaaaata
    22741 tcatgtgaac aaattgattt tgctgattgg tttgatctgt gtcttagtga caagtatcta
    22801 cctctttatt ttagcaaaac aagcaaatgt cgaaacgtta aaatcaggat taagccaatc
    22861 gacagtcatt tatgataaga aaaacgaaga agctggcaca ctgtacgccc aaaaaggaac
    22921 atatgtagaa ttaaacgcga tttctcccta tatccaagat gcagtaatct cgacagaaga
    22981 taggaatttt tacgagcatc acgggtttga tatcaaaggg attgcccgtg cagcagtccg
    23041 aatggtcttg tctggcggaa catcaggggg cggaggaagt acgatcactc agcagcttgc
    23101 caaaaatgcg tatctgacat tagaccaaac gtttgatcga aaagcgaagg aattattttt
    23161 ggcaatcgag atcgaaaaga agtacagcaa agaagaaatc ttgaccatgt atcttaacaa
    23221 tgcctatttt ggcaacgggg tatggggtgt ccaagacgct tccagaaagt attttggagt
    23281 agatgcaacg aatgttacgc tgtctgaggc tgctactttg gcaggaatgc tgaaaggtcc
    23341 tggtatttat aatccgatcg atcacccaaa aaatgcgaat gatcggaaaa acacagtact
    23401 aagtgtaatg gaagaaaacg gaaaaatcac aaaagaacaa gaacaagcag aaagccagac
    23461 agatatcagc gcgtatctta atgacacata cgataattca gattctggtt atcgttatcc
    23521 ttattatttt gatgcagtga tcgatgaagc agttaacgag tatggtcttg atgaagaaga
    23581 tgtcatgaat aaaggctata aaatctatac agctttagat caggattatc aaaagcaatt
    23641 agaagctact tatcaaaaca gtgcattatt cccagcaaat gcttcagatg gtgccatggt
    23701 ccaatctgct tcagtagctt tagatccgaa tacaggtggt gtacaagcac tagtaggacg
    23761 aagaggagat catgtcttta gaggattcag ctttgctaca cagatgcgtc gttcaccagg
    23821 atcaacgatc aaaccattaa gcgtatatac accagcactg gaagctggat acaagccttc
    23881 cagtatcttg aaagacgaac cgcaaagtta ttacgatgcg cataattttg acgggacata
    23941 ccaaggagaa gtaccgatgt atcaagctgt tgcacaaagt ttgaatttgc ctactgtatg
    24001 gcttttgcat gagatcggtt tacaaaaagg atatgataaa gcagaagaat tcggcctgcc
    24061 tttagcaaaa tctgataagt attatggctt agcccttggt ggactggaaa aaggagtatc
    24121 tccattgatc atggcgggtg cttacagtgc atttgccaat gatggtcaga tgtatacgcc
    24181 gcatcttatc acgaaaatcg ttgattcgac tggagcggtg atcgtcgata acacaaacaa
    24241 aaaaccaaaa caggtcatat caaaggaaac agccgatgaa atgaccagca tgcttcttgg
    24301 tacattttca aatggaacag cggctgctgc gaatcctgca ggttatacga tagcagggaa
    24361 aacaggaacc acagaaacta atttcgatgc cacaaaagca aatgaccaat ggatgatcgg
    24421 ttacacgcca gacgtagtga tttcgacatg gatgggttac gaagaatcca gcaagctgca
    24481 ctatttggaa gggacaagtg gaaatgttgt cgggaaagtc ttcaaatcag cggcagaagg
    24541 catccttccg tatacttcaa aaacaggatt tagtgtagca gatgcctatg ccacaggagg
    24601 acaagtggta gctgcagatc aagttggaaa cacaggaaat tctaatggag agtctggaaa
    24661 ttggcaagat aacttgaatc aatatggtga acaagcaaaa gaagggctga aaaacttcgg
    24721 cgatatggtg aaagaaggcg ttcagggaat tggtgaagcg gctaaagacc tctggcggaa
    24781 atatcaagga gagtagcccc tttgaaaacg aataacccca tgttacaata gagagtaact
    24841 actaaaagaa aagagggcat aacatgtcaa acatctacga tagcgcgaat caaatcgaac
    24901 gtgagatccg tgaattacca gaattcaaag cgttgaaaga agcgtacgag aaagtacaag
    24961 caaacgaaga agcacacaaa ctgttcaaag acttccaagc gatgcaaatc gaattacaag
    25021 aaaaacaaat gagtggacaa gagttcagcg acgaagatgc aatgaaagca caagaaatgg
    25081 ctgtgaaaat ccaatcagaa gaagtaatca atgacttgat gcaaaaagag caaggcttca
    25141 gtacaatcat caatgacttg aaccgtatca tcatgacacc agttcgcgac ctttacagcg
    25201 aataaaacta ttttatgaaa caacagaggg tgtgaaagag acgttcggcc ttgagcgatg
    25261 acaaaattgc ttcttattgc cgataggctg tctcttgaac accatttacc aagaggtcgt
    25321 gagcctaccg tttaactctg agttacaagg aacaatttca aaaaacagct tctcatgttt
    25381 gatgactatt gtgacttgtg accgaggagt tggcaggaga acaccgttta ttcagaaata
    25441 ggagctacga caaaagtctt gtcatagctc ctattttttg tcattcattt ttcaagcggt
    25501 agaaatagcc tttttgagct aacagttttt cgtaagtacc tatttcaacg atttttcctt
    25561 catcgatcac aacgatttta tctgcctctt tgatcgttga aagccgatga gccacaataa
    25621 aagtagtggg tgtttctgtc aggtaattca gggcttgctg gatttttttc tctgactggt
    25681 tatctaaagc tgaggttgct tcatctagca aaatgatttt tggctgacgt atcaacgctc
    25741 gtgcaatgga gatacgttgc ttttggccac cagacagctt gttgccatgt tcgcctacta
    25801 aggtatccag accatcagga agctggtcaa tcagtgaaga aagttgcgca gcttcgatga
    25861 cttcatctaa acgttctttt gatacgtttt tcaagccata agtgatgttc tctttgatcg
    25921 aagcggagaa caacaaagtg gtttgaggaa caacggctaa ataatttcgc acacttcgca
    25981 tatccagttc atccaaaggc tgatcatcta gaaaaatttt tcctgaagtc ggctggataa
    26041 atccaatcaa taagttaagg agtgtagatt ttccagagcc agatggccca acaaaagcaa
    26101 ttgtttctcc agctttcacc tctagagaaa aatgatcgat aatcggtttg agtgagtccg
    26161 gataaagaaa agaaacatcc tcaaaacgaa aatttccatc caaatgttgg atttttttct
    26221 taccgtgata agtttctaca tcgccagcaa tcaacagttc gccaatagaa gtgatagatt
    26281 ccatgccttt tgaaatcgta ggaatcagcg tgatcattcc agaaacggaa ttgacgatcg
    26341 tcgtgaaata cgtctgatac atcacgacat cgccgggttg gatgcgccct tgtaaagcta
    26401 atatcccagt gaaaatcaaa caaatcagct gaaatatctg aaaactagcc cagctgactg
    26461 atccgaaaac agattgcagg atatctaagt ggaatccttt ttcatagatt tgagtaaaat
    26521 gcttatttaa gcgagttgtt tcgtgttttt ctaacccatg agctcgagca atcggtgcta
    26581 attcgatcac ttcgatcact tttgcagaag tctcttccat ttcttgcctg aagtctgagt
    26641 tggactgtct gatcctttta cggaaaaaga gagtaacgaa tgcggcgaga ggaacagtca
    26701 ataagaaaaa catgaaaaca acaggacttt tataaagcgt gatacctaaa gctacgaata
    26761 aattgacagc gatatttaat ccgctgacaa atacttgaga ggacaacgtt tggatagctt
    26821 ctacatcacg gatgatcttt gactggattc gtccagattg caattctttt tgataaggaa
    26881 tagatagttc ttggattttc ttgataaggg tcgctcttag tccagcttct acttgacgga
    26941 tcgaagtgct atggtatttt acatgaaaat aattcgtcaa tatattttga ccaatcagac
    27001 aagccatcaa aaaagcgttg aaataaatgg cctgcaactg agaagaatct ttcgatgaag
    27061 ctgcattgat tacattggca atagcgatcg gcattaacca agatggaaga tgtttgataa
    27121 taaaaaagag tcctgacatg gcaaaacgcc aataatttcc ctgataaaga tgcagcaatg
    27181 tctgaaaagc atttgcatga tatttttgat aacttttctg tattcgttcc tccataatct
    27241 tctccttaac aatcttggta aataaactgc aagtgttcta ttgcttcagg aacataaatc
    27301 tcaggagtag cttcaagagt ggcgtacatt agaggacgct catatttgat ataatgcagt
    27361 accgggcgga aatctaaaca gcccttgcca acaggtacca tgcggatctt tccattttcc
    27421 atgatatagt ctttgagatg aagcgctgta atataaccat gtaaattgtc caaggcacct
    27481 cggatcactt tttcctgatc agcatgattt tctttatgca tcaaattcgc acaatctaaa
    27541 atgattttta aatttggtga agctacttca tcgattaaac gtttagctaa ctgatagtta
    27601 tagattggat gattgatccc tgcttcaaca gcaacagtta cgccaaaatt ttctgcatga
    27661 gcgactaatt caatgataga atttctggcg atctgataag cttcttcagt aaaattttct
    27721 tttgtgtaac cgacagagac actaccggtt tccgtagcaa tcatcttggc ttgataggca
    27781 gagcacagag caatttgctg tttgaaagtt gccaatgctt gtgcacgaac ttcttgattt
    27841 ttgctggata ggttgatata gcatcctaaa atggaaagtt cgatattgtt tttttggaag
    27901 tattcaccaa aataggcagc actcccaagt gtcatgtcag ttaatttaag ttgttcagga
    27961 aatgcttttt gtggtgcaaa ttggatatgg gacaagtgaa gctgtgatac tttttgaacg
    28021 atttcttcac gatttcgaac atctaaatcg tgggcacgga tgcctaaatt taatggaaac
    28081 atctcaaact cctttttgta aataattagc aagaggcaga cgggattctt ttatcaattc
    28141 aacaattatt cgggcaactt tatcagcgcc ttctggacta aagtgggtat tgtcttttag
    28201 tccttctggg taatttttac aagtatcagg tataagatgc aggtagaatt tttttgtctc
    28261 ttcttttgag aaggtctgga acaattcttg tgatcttgag aacacatcta aaagaggaat
    28321 atggtgtttc tcagcaaatg cacgcatcgc ttttggatag tctccaagta tatctggatt
    28381 caatgttccg ttttctaagt aatctcgtcg cgtcacagat gtcagtaaga ccatttggac
    28441 gttcgctttt tttgcgcatt caaaaaatat ctgcagattt tttaaatagc taccgaaggg
    28501 aagcgtacct ctttcttctt ggattttctg gtcgttatgt ccaaattgta caaataagaa
    28561 atcattcggc tgaaactgtg aagctagacg ggctaacctt ccttcctgga taaatgattt
    28621 ggtgctgcgt ccattctttg cttggttatt gatctggatc tcgggtgaaa aataagcaga
    28681 gattttttct ccccaacctg tctcgggacg cttgttttca tctttttctg ccgcagtaga
    28741 atcaccggca atatggatag taggcatgtt atctcttctt tcataaaggt ttataggcaa
    28801 tgaagcagaa cagcaagaga agaagacgga gcaaatttgg tccgtcttct tctctaaaac
    28861 gtggataaac ggattccgtt atttcactat cctgtttttg attcgttact gttactatta
    28921 atcaattagg caaaaaagcc aaagtaattt ttagcatttg tataactaat cgcttgaact
    28981 agacttccta aaagttgttc atcttcaggt gcttctcctc gcatgaccat ttcgcctaaa
    29041 aattcacaaa gaacacgacg gaaatattca tgtctagtgt aggacaggaa acttcttgaa
    29101 tctgtcagca tgccgacaaa attccccaaa gcactaccat cagcaaattg tgtcaattga
    29161 tcgcgcatac cagctcgagt atcgttgtac caccatccag aacctaactg cagttttcca
    29221 ttctgttctt tttggaaaca gcccatcaaa gctaaaatcg caggatagtc attcggattc
    29281 aatgaataaa ggatcgtctt tggcaactga tccgtttctt ctgcacggtt caataatttt
    29341 tgcagaggaa tagtcaaaga aagatcattc attccatcat agccggtatc gggccctaat
    29401 ttttccaaca tttgtgtatt acagttacga taagcatgga tgtgcagctg catcgtccaa
    29461 ttatgagaat gatagaagtg ggtcaaatgt atcagtgttt ctgtacgata agcatcgatt
    29521 tcatctgaag ataatagttt gttagctcgt gctttttgaa aaatctcttc taatactgtt
    29581 tcatccgctt ctttatagcg taagatgtct aaagcgtggt cggaaacacg acatccatgt
    29641 tgatggaagt attctatccg ctgccctaag acttctatca gttcttgata ggtggtgatc
    29701 gtttggtcag ctgcttcttc cagtagtgtg acccatgcat taaatccttc tttttcaata
    29761 ttgagtgctt tatctggacg gaatgaaggt agaaccttca aatctggttc ttcatgagca
    29821 agcaactgat gatagtgcaa gtcgtctgcg ggatcatctg ttgtacaaat cacttctaca
    29881 ttcgattttt ttgcgatttc ccgacggcga aaatcaggag ctgccaaaat ttcatttgct
    29941 tgtgtccaaa ttttctctgc attttcttca tttatcaaca agtcaatacc gaagaaacgc
    30001 ttcaattcaa gatgtgacca actgtaaagc ggatttccga taatttttgg tacggtttga
    30061 caccaagcta aaaatttttc aaaatcagaa gcatttcctg tgattttttc ttcaggcacg
    30121 ccgcaagctc gcatcaagcg ccatttgtaa tgatcgcctc ctaaccaagc ttctgtcaga
    30181 ttgctgaaat tgttgttttc gtaaatttct tttggatcta agtgacagtg ataatcaata
    30241 atgggcatgt tttttgcgta ggaatggtaa agctttttcg cccaatcgtc ttttaataaa
    30301 aaatcatcag ataaaaacat aaatcttcct tctttctttt tatactgttt tatgaaaatc
    30361 aaagtgttac tccgttttta aaaatggcaa tttctcgaac gtcattttgt tcatttttcg
    30421 tttcttctcc actagctaca gcgatgattt tttgaacaaa cgattctaag attacttcca
    30481 ttggttgttc taataagacg cctgcattaa aatccatcca atgacctttg cgttcaaaaa
    30541 gagttgtatt cgtagatacc ttgaccgttg ggacatatga gccaaacgga gtccctcttc
    30601 ctgtggtaaa caagaccaac tggcaatcgg atgaagcaag agcagaggca gctacaagat
    30661 cattcccggg agcttgcaat aaactaagcc ctggttttct gattttttcg ccatattgta
    30721 gcacatcaac gacaggagag cttcctgatt tttgcgtgca gcctaaagac ttatcttcta
    30781 atgtagtgat cccacctgct ttattaccag gagatgggtt ttcgtaaact ggttccccgt
    30841 aagacaagaa atactgtttg aagtcattga tcaagtcaac gattgagtca aaaacttctt
    30901 cattttccgc tcgtgccatc aatacttgtt ctgcgccaaa catttctggc acttctgtta
    30961 agatcgtgct gcctccttga gcaatcaagt agtcagaaaa tgcaccaagt aaaggattag
    31021 cagttattcc cgatagacca tcagaaccgc cgcatttcaa accgacattc aacttagaga
    31081 gcgggactga tatgcgctgg tcattttccg ccgctgttaa aagctcttct aatagagcca
    31141 caccttgttc gatctcatcg taaacatctt gagccactag aaatttcact cgttcttcat
    31201 catattcacc taaaattttt ttgaattcag gaactgtatt gttctcacaa cctaatccaa
    31261 atactaaaac tcctccggca ttgggatgat ttactgcgtc cgctaaaatt tctcgagtat
    31321 tttgatgatc ttttccaagc tgcgaacagc cataaggatg ctttaaaatc gtaatatggt
    31381 caaactgtcc cagatctgga tgtttttcct tgaactgttt gacgatcagt tcagcaatgc
    31441 cattcacaca cccaacggta ggtactaaaa acaaatcatt acgaatccct acttttccat
    31501 tttttcgcaa gtaaccttga aatgttcggt tctcaaaaag gtaatgactt ggatggacat
    31561 ctttttcata tcgataatcc aattcaccag aaagattggt ttttacatta tgagtgtgca
    31621 gccattgacc ggcagttacg tctgtcgtca catgaccgat tggatagcca tatttgatca
    31681 cgttgtctcc agctttcaaa tcacccaatg caatcttatg accttgcggg atatcttcaa
    31741 gagtggtgat cgtttgctga tcaatcgtca gttgtgtttg ttttggaata ggggttaatg
    31801 cgacgaccac actgtctcgt cgatttaatt tcattgttgg ttgcagggtt tcaagcatgg
    31861 accatcgttc ctttcatttc ttgtaatact gaccggacac ctttttgatc gatctttgca
    31921 gctatttctt gaactgtatc tgtcacattc ggtatttgag acaaatcttc tccccaaagc
    31981 gcagcgtttt gcaataatcg aggaatagct gttccattat cagaccaagc atcagtaaat
    32041 tcgcttatcg tcttttcatc atcatgtggc tttacttgat cgcctcgata cataagaagt
    32101 agcgcagcta gtgaaacagt gattaacggt ggtacctgat tttgttcttc gatatacttc
    32161 ttgaacactg gaagcagacg ggtgctgaac tttgaaacac tatttaatga aatcgcttct
    32221 aatttgtgat gggcaaaagg attcaagaaa cgttctttga tttggtcagc ataaatggct
    32281 aattcatctt taggtaaaga aagcatagga atcaattcta gattgaataa ctgatcaaca
    32341 tatgcggaga ataaaggatc tttcattact tcttctacag tttccaattc cgccaacaaa
    32401 gcaagaggga ccatcgctgt atgcggtcca ttaagcaaat gcaccttacg ttcacgataa
    32461 ggagtcatat catctgtgat gatgacattc aagccagcct gtttgaatgg tagttgattc
    32521 tccaattctt taggcccttc gatcacccaa agcatgaatg gttctgcttt gaccatcaat
    32581 tgatcttcat agttatgccg ttgattgaaa acacctgcat cttcgcgagg ataacctggg
    32641 acgatgcgat caactaaact acaacagaaa acattttctt tttctaacca ctcaacaaaa
    32701 gcaggttcta aatcccattt ttctgcgtag cgtaaaatga tttcttttag acgttcgccg
    32761 tttctgtcaa tcagttcgca aggaatgatg gtaaagccag ctttgtttaa tttgaaacgt
    32821 cggtataaaa aggctgtcag tttgcccggg aagctctgtg ggggagtatc tgttaaatta
    32881 tcagtctcca cgaattggat tcctgcctct gttgtattgg agacgatata ggccaagtcg
    32941 tcattttctg ctagagatag ataagcatcc cattcatcat aaggattgat catttgttct
    33001 actacggtga taatctcgga agtatcaacg atttcgccat tgctgagtcc ttgtaaaatg
    33061 accgtatata aattatcttg ctggttcatc atatttccaa gaccttgttc taaaggttga
    33121 atgattgcaa cattaccttt aaacaattgt tggttattca gctgctgaat ctgccaatca
    33181 ataaatccac gcataaaatt gccttcacca aactgaagaa cttttacagg tgcttcgttt
    33241 tttttcacta attcttttgt cagttttttc atataaactt cctttctgtg ttatgcacac
    33301 gttaacattt ttatataaaa ttacttgtag tttacaagta attgatcgac tcacgaagga
    33361 tcaacaaggt ggagagctca attttagatt gttcgatcgt cctgccttcg atcaaatcta
    33421 gtaaaagctt tgttccttct tgacacattt ctttcaaagg cttacgtacg gtggtaagcg
    33481 gcggattgag ataggagacg actggagaat catcgaaccc gatcagagaa atgttctggg
    33541 gaacacggag gccagctaaa tgtacagctc tcaatgcacc aatcgctatg tcgtcgttgc
    33601 cgcaaaaaac cagagtaggc aggtcagaaa gtgataatag gtattccatg ttttggaggc
    33661 cgctttctaa gctgtaatct cctgttaaaa aataggctgg attgacaggg atgctcgctt
    33721 tttttagact tttcaatacc cctttttccc gttcttttgt cgaacgaaaa tttttctttc
    33781 cgccaatata agcgatcttc gtatgtccgc atccaatacc gtaatctact gcctgcataa
    33841 caccggccgc atcatcggca gtgacgttga taaccgctgg atcattgatg tgacgattga
    33901 caacaacgaa aggaaattct ttttctttga gatagtcgat gaaaggctga tcatcatcac
    33961 tttgactcat aacgatcagt ccatcgtagc gttgcaggtt gatttctgtt aaatcaacaa
    34021 catcgatact ttcaacagat aaactgtaat ttgtgtctaa tactgaatgg atgcctgcaa
    34081 tggaatctgc taggaaattt gatgaagttc ctttatgcaa acttgagaaa aatagtccga
    34141 ttagatattt tttttgattc actaaacctt ttgcactata gtttggcgaa taattcattt
    34201 ccttagctag ttgtcgtatt ttttgttttg tttcattttt tattaaactg ctgttattca
    34261 aagcacgaga aactgtcgta tgagaaacgc cagctgcttt agcgatatct ttgatcgtta
    34321 ccattccatc attttcctta ctttttcact ttttgttaac gcattcatca tattacgata
    34381 actacgataa gtcaatagat ctttgatatg aaaagattgc acacgttaaa aattacttgg
    34441 atttttattt ttaattatgc tattcttgaa agcggggaat gctcatttaa ttagatgagt
    34501 atcaatttta cagaaaaatg aaagcctttt attttaaaag gaggagagga agaaaatgaa
    34561 gaaaagtaca gtattttata aaatattttt accgatgttt ttattaggag ccgtacttgt
    34621 cataggattt agtttattca tttaccagaa tacctatgaa tcgatcgaat cgagttattt
    34681 aacagacaaa aagaatttgc tcaggcaagt taaaactaac gttgaatgga aaattagaac
    34741 gattgaatat tcgttttcta cgtatggttc gaccaaaaat ttctcggaca tattcaagca
    34801 tccgctgaca tatacagatt actccactta ttctgaaatc aggaaagaac taaattttat
    34861 agaaacgatt gttatggatg ataataatta tgatttagtc agtttggctg gtaaatgggg
    34921 agtaatcaat ggatcgttga gtcaactgac cgaagaggaa gttgaaaagt atcaacagaa
    34981 gtacataaat aacaaaaata atttattttg gcaaaagaaa aacaaaggaa tcgaaatggt
    35041 gatttctttg ccaatgtttg aaaaagaaaa atatgcattg ggaattgcta cgatagagaa
    35101 acatacaata gaacaagttg ttggtgaaag tggagaagac atactttcta ttgaaaacga
    35161 agttggcaac ctttttacta ctcagacagt aaaaaataaa gagcaaccaa ctgtattaac
    35221 ggacgtggat ctagattaca atcagctgaa agtgataaga gaaaaagata aaacgtatat
    35281 agtactgaaa tcagattata ataattggat ttacagatta gaagttgact ctagtgcaat
    35341 tggcgcaatg atccgcaatc tgagaatcgg gctagttgca gtgtctttaa cactggtagg
    35401 actcattggt cttctttcct acttattttc ggacagattt gcccgtccga tttctcaaat
    35461 acaggaacgt ctgaatctta aatcaaaagg attcagtggg aaagaactag atttggtcgc
    35521 tcaatcagtc agtcggatca taggagaaaa agaagcgtta agtgcacact tagttaccca
    35581 aaagccacag ctggaaacgc tatttgtact tagtttattt agaaatcgag tagaaaggcg
    35641 agaactagat cagcggttgc agcaatttgg ttatagttct caaaatgact gctattatac
    35701 agctttggtt caaatcgatc tgttagaaga tagtcacggt ggggagcgtg atttgctact
    35761 tttagcgatc aacaacatga tcacggaaat tgtgccaaag gaaaatcgaa tgctgccgat
    35821 cgttttgaat gaagaaatgc aagccactat ttatcgaatg gataaagatg atgcagaagc
    35881 aagcaaaaaa gtcatggagt attgccgact cattcaaaaa cgtgtaaaag aatacttgaa
    35941 tttaactatc agtataggca tcagtaaccg gttcgaaacg ctgaatgaaa gcaagcaatc
    36001 ggttgatcgg gcaaaagaag ccctgtatta tcgtgtaaat actggtccaa gttcaattat
    36061 tttttatcag gaaatcgttc ctgctgctca tgaaaaaaca cttattagat atccgataga
    36121 agaacaaaat cgattgtttg aagccattcg ttctggaaat caggaagtga agaatttagt
    36181 acatgaattg attgatgcat tgtttgcaca aaataaaaat cctttgagtc gggaagtagt
    36241 ttcggtccgc ttgatcaatg aactcgttca attaggacag ttattgggag tagattcaaa
    36301 aaactttgat aacatgaaac aaatttatgt aaaagcactg aacaattatc atcccaaaga
    36361 actagaaaaa cttgttttag aacaattagt tctgccaatc acagaatgct ctcaagcaat
    36421 cactgatcat gaatttaaaa atttgtcgga gaatattatg catatcgtct acacagaata
    36481 tgatcgtgat ctgtctttag atgtgatcgc tgataggttg cattataacc ctaactattt
    36541 aagtaatgta tttaaaaagg aaacaggaga aaaatttggt gattttgttc aaaatcatcg
    36601 tttagaggta gcaaaaaaat ggttgaaaga gactaacctc tccgtaaaag agattgcaga
    36661 aagattgcaa tatcgaaatc cgcaaaattt tattcgtttc tttaaaaaga aggaatcgat
    36721 tacgccggga gaatatcgaa aaaaatattt gtgaatcaag aggctgtttt tcttgtggac
    36781 tgattcaagc aataaaagaa gttagaataa ccctagtatt tgtatttatg gatagttaaa
    36841 tttcaaggct aagcacgcaa aaagaactgt gacaaaagtc ttgtcacagt tcttttttac
    36901 gaataaatgg cgttcaagag acaggctatc gacaataagg cataattttg tgaaatatgg
    36961 gaagctattt ttcaaaatcg cttcttattg ctcctgtggg ttactcgtcg caatgtttgt
    37021 gagagttttt atcatcgctc aaggctgaac gtctctttca caacctctga tacacggtgt
    37081 tccaggagta gattcttcga aaaataagcc gaaatttcac aaaaatttaa gaagcaattt
    37141 tcgtaaatgc cttcttattt cttgaagctg accacttctg acacaactac cattttgcgt
    37201 tcagtacata atcacccttt gacagaacct acgagtgctc ctttgacaaa atatttctga
    37261 acaaaaggat aaacaatcag cataggcact gttgcaataa cgataacagc cattttaact
    37321 gtttgtgctg gtggaatcac atcaacggca ctactttctg cttgcatccc acttgataca
    37381 atgacgattt ggcgtaaaag aatctgtatc ggccatttag atgaatcgtt gatatacaaa
    37441 atagcagtca tataagtgtt ccagtaagta acagcataaa aaagcgagat agtagcaata
    37501 gacggtaacg ctaatggcag cataattttg aaaaatacac caaaatctgt gcaaccatcc
    37561 atttttgctg attcttccaa actatccggc aaggcttgga aaaagtttct cataatgatc
    37621 atattcattg cattaacagc cacaggcagg atcatggccc agtaagaatt gaccagccct
    37681 agagaacgaa caactaagaa cgttggaatc atccccccgc tgaacaacat agaaaataca
    37741 acaagaaagt tgacgaaacc tcgaccaaac aaatactttc tggaaagacc gtaggccatc
    37801 agtgaagttg cacacatact gacgatcgtt ccgacacctg taacaccaat cgaaacagca
    37861 agtgctctaa aaatggtcgg cgtagaaaga atgtagcgat acgcgtctaa agaaaaggta
    37921 gtaggaaaaa ggataaactt tttcgcgacg acttcttgtg tagaagcaaa agatgtagcg
    37981 atgatattta aaaaaggaac gatacagatc aaagctagca aaattagaaa cgtattgttg
    38041 aaaagtgtaa aacttctttc tcctatagag actttctttt tcatatagat aggctcctcc
    38101 tcaaaataaa ttaaatgttt ctgtttctat atgttcaatt tatcatcggt gaaagattac
    38161 gtatataatc atttcctatg ctaagtgtca gatagaaaaa aatagaaggt ttgctatgcg
    38221 tagtttattt gtgaaaaaat acactttatc gttttgtata gcacaaaaat cattgctatg
    38281 taagcgtttt tacttacggt aaaaatgatt atatacgtaa ttcagatagt tatctatcat
    38341 gaagtcataa gcagcaaaca ttcacaaaac taaggagggg cttatggaaa gtgtaaagaa
    38401 acaagaacca tttcaactga cgctatcgaa aaaagaagaa aagctcagaa gacgaaaaaa
    38461 aataattgca ggaatcaaaa cgaataaatt tttatatgtg atgattctgc cgggagtcct
    38521 ttatttcttg atttttaggt atcttcctat ggggggactc gttattgctt ttcaagatta
    38581 tcaaccattt ttaggaataa tgggaagtcc ttgggtcggt ttcaaacatt tcattcgttt
    38641 gtttacagaa ccgacattct ttacattatt aagaaatacg ttgatcttgt tcggattaaa
    38701 tatcttcgtg ttttttccga tgccaatcat tttgtcttta ctattaaatg aagtaacgaa
    38761 caaacgattg aaaaacggga ttcaaacgat catttacatc cctcacttca tgtcttgggt
    38821 aatcattgtt tcgattactt atgtattttt gaatgttgac ggaggggtat tgaatgaatt
    38881 ccttgcaaca atgggatttg aaaaaatcag ttttctaaca tcccctgaat ggacacgcac
    38941 agtatatatc ggacaagtga tctggaaaga gttgggctgg tctacgatca tctacctttc
    39001 agcgataact gcagtcgata cacagttgta tgaagctgca gaaatggatg gagcaggacg
    39061 cttacgcaaa acatggcatg ttacattgcc ggcaattcgt ccagtaatca ttaccttgct
    39121 gattctaaaa atcggtcaga cattagactt agggttcgag catatgtact tgttattgaa
    39181 ttcattgaat cgaagcgttg cagaaatttt cgacacctat atttatacag ctggattgaa
    39241 gaatggacag ttaagtttca gtacagcaat gggattgttt aaaggggtcg taggattgtt
    39301 tatggtaatt ttagctaata agattgccaa aaagctagga gaagacggcg tttactaaga
    39361 tagaaagaga gggaaagata tgctgcagtc attagataaa ataaacggaa ggctaaatcg
    39421 tattttacag ttggtttatt tgaattttct gtggggcggt ttagtcatcg caggtttggg
    39481 agtttttact ttcggtcctg catcgtatgc gatggttgca gtgattagaa aatggctgcg
    39541 ctcaaaagaa acgtttcctt tgacgaaaac gtacttcaca tattttaaag aaaactatcg
    39601 tgaaaccttg ctgatgagct ggatatatgg cgccatcggg attgttttac ttgtggatct
    39661 ttctttcata cacaattggt atcttaggat cgctttgtat attgctgcgt tcatatatgt
    39721 gctctcagca ctctatattt tcccaatcat ggctcattat gattggaaag gatatttttt
    39781 caaaatgaaa atggcatttt tattcggatt ctcacatctt cattactcat tagtgttgat
    39841 attaagtatg gtagggattt atctgatgat catccaaaca atgccaggtg ttttaacctt
    39901 tatcggtggc agtctcttct tttccgcagt cacgtggaca gcaaattcta tattttgcca
    39961 tttggaatgg aagaactcat atacagaaaa aacagaagaa aacaaaaata ttattaaaac
    40021 agtgaaggag aaaatttatg aaaaaagcaa cgctcgtaaa attaggtctt agttttgcag
    40081 gaattctagc acttgccgca tgcggcagca gttcaagtaa cagttcttca gagacagaag
    40141 atggaaaagc taaaatcact tggttaaata ttttgcatca tgcttcaccg cctacagaca
    40201 cgattgtgaa cttgatcgaa gaaaaaaccg atacggaact gacattcaac tggattcctg
    40261 atgcttcaaa agaagaaaga ttaacaactg cattggcttc tgatgaacta ggagatatcg
    40321 ttacacttca aattgcgatg ttgaaaaact cttctgtccg caatgcgtta aaatcaggcg
    40381 tattctggga tgtatcagaa tatttaaaag actataaaaa tttaagtcaa atttctgaag
    40441 atagaatcga agctgcgagt atcgacggtg ccttgtacgg cgtaccgata caaaaagact
    40501 acgctcgtgc tggcttagtc attcgaaaag actggttgga taatctagga ctagatgttc
    40561 caactaccat ggatgagctt tatgaagtag ctaaacaatt tacagaaaac gatcctgatg
    40621 gaaatggtgt ggacgacaca gttggttttg gcgatcgtgc gcctagtgat attcgttata
    40681 ccagctttaa acttttcact tcttattttg gagcaccaaa tggctgggct gtagacgata
    40741 atggcaaatt cactccagaa tttgatacag aagagtatat gaaagctttg aatttttcaa
    40801 gagatctatt tgagaatggc tatttggcac aagactttgc agttacccaa aagactgatc
    40861 agcaagaaca atttgcacaa ggaagaactg gaatctacac tggaatggtg gatatcaaga
    40921 atctgaagac gatgggtcaa ggtattcaag atgatatgga attagtgcct gtaaacaaga
    40981 tctcagatgg tgaaggcggc ggttatcatg tttggtcaga aggaaatggt attggcggct
    41041 tgctagcatt tcccaaatct caagtaaaag acgaagcaca attgaagaaa ttacttcaat
    41101 ttgttgatga tcttttagaa gaagatgtgt ataaattgat gactggcggt atcgaaggaa
    41161 cgcattatga attgaatgat gatggttcta tcgaatttat cgatatggat ctttggcaac
    41221 aagaggtgca accgttatca agctctcgtc ctagtgaagt gacgttctct ttcaaagata
    41281 cagaccctga aaaagaattc tctaatcaat tgatcaaaga aaatgaagaa tttgctgtaa
    41341 tggatccttc tgtgccattg gattcaccga cgaacaatga agtaggatca gaaattgaaa
    41401 aaatcgtcat tgatgctacg gtgcaataca tcatgggaca gcttgacgaa gatggattca
    41461 aaaaagctgt agaagactgg aaagcacaag gaggcgatcg aatcacacaa gagtacgagg
    41521 aagcatacaa agcagcggca cagtaatata gacgattggg acaaatactt cttggtattt
    41581 gtcccaaatc ctattttaat ttttaaagga gagcaaataa tggaaaactg gtcaaagaaa
    41641 ttagcaaaaa gtatcatgga aagaacacct cgcttatatg aagaaaagtg gtataaagga
    41701 aaatggtctt atgactatgg cgtcgtactt aaagggttcc aattactttg ggaacgaacc
    41761 caagaaaaaa tttattttga tttcataaaa gacaatatcg actatttcgt gcaagaagat
    41821 ggaacgatcc gtggctacag cgttgaagaa tacaatatcg accatgtaaa tacaggaaag
    41881 cttttctttt tattgtacaa agaaacaggc gaagaaaaat ataaaaaagc agcagaactc
    41941 ctttcccagc agttggcaaa ccatccacgc acatccgaag gagctttttg gcataaagaa
    42001 atttatcctt atcaaatttg gttggatggc ttatatatgg gttctccttt ttatgctgaa
    42061 tttatccaga attttagtga agaaaaagat taccaagatg ttttgagaca gtttgaaatc
    42121 agttataaac atctattcga tccaaaaaca aatttgctga ttcatgcatg ggatgaaaag
    42181 aaggtccaac catgggctga tccaaaaaca ggtctatccc atcatttttg gagccgatcg
    42241 attggctggt atttgatggc tgcagcagat acctatgaat tacttcatga agaaacagat
    42301 tgttctttgc tgaaagaaat tctagaaaag acactggctg cattacttcc atatcaagaa
    42361 gaaaacagcg ggacatggta tcaagtaaca acagaaacaa aacggaaagg aaattatctg
    42421 gaagcttccg gcagtagtat gtttgtttac gcaatggcta aaggaatacg tttgggactg
    42481 ctgaacaaag aagaatggct tccacaagtg aagaaatcac atcaaggatt acttgatgaa
    42541 tttgttctgg aaacaaaaga aggctggctg aacttgaata aaaactgtca agtagcaggg
    42601 ttaggcggag cagatcagcg agatggttca tatgcttact acatcagtga accaattatt
    42661 tgtaatgatc aaaaaggcgt tggtgcattc ttgcaagcat tgattgaagt ggaggcatta
    42721 taaatatgta tgatattttg acatttggcg catcaattga tgaattgaat actgaagcaa
    42781 tacaacaagc cattgatgct gcagcaagtg acggaggcgg gaccgtagtt gttccagcag
    42841 gtgaatttct aacaggagct ttatttttaa aaagcaatgt cgaacttcat ttaagcgcag
    42901 gagcggttct gaaattctct gacgatccaa aagattatcc tgttgttcat tcacgttggg
    42961 aaggagtcca tcgaaaagtt tatgcttcct gtatctatgc tcaaaatgta gagaacatct
    43021 ctgtcactgg tttcggtaca ttagatggaa atggaaaaaa atggtggcat acttttagaa
    43081 atgaaccaga taatctcgct tatcctcgtc ctaaattgat gagtttccat aactgtcatc
    43141 gaattactgt gaaagatatt aaattgatcc agtcaccaag ttggacgatc aacccgattc
    43201 tttgcagtaa tgcaacgttt gataacttga cgatcttgaa cccagcggat tcaccaaata
    43261 cagacggaat tgatccagaa tcatgcaaaa atgtgcgtat tagtaattgc catattgacg
    43321 tgggagatga ctgtattgca atcaaggcag ggactgaaga tacgtacgaa aggatcgctt
    43381 gcgaaaatat cacgatcaca aattgcacga tggtccatgg acatggcggt gtcgtattag
    43441 gaagtgaaat gagtggtagt attcgtaata ttaccatttc aaattgtatc ttccaagaaa
    43501 ctgatcgagg aatacgattg aaatctagac gaggtcgagg cgggatcgtt gaagatattc
    43561 gagtatccaa tatagtcatg gataatgtga tgtgtccatt tatactgaat ctttattatt
    43621 tctgtggtcc gcgagggaaa gaaccgtatg tatgggaaaa aaaggcttat ccgatagatg
    43681 aacggacacc agcattcaga aggatccatt tttcgaatat cacggcaagg aatgtccatg
    43741 cttctgcagg ttttatttat ggattagcgg aacaattcat acaagaaatc acatttgaca
    43801 atatcgatgt ctcgatggcc caagatgcag ttcccggtgt tcctgctatg atgacaggaa
    43861 tagaggaaat gagcagacaa ggattttata ttggctttgc gggtaaggtt tcctttaacc
    43921 agatgtcgat tgaaaatcac gagggaccag catttctatt agaaaatact aaagaaatca
    43981 gtattgagaa attccaatca aatcaatcag aaaatatgga tgaactggtt gttcgtaaaa
    44041 actttgctta tgcagttgaa tgatttttta ggtgctccat ctagcagaca tacccctagt
    44101 ggaaaacgat tataccgaga aaaacaaaac ggttttatgc ttgaatacta tcaattgtac
    44161 ttaaatgaat tggaaacagt accagccctc tatgcttatc cagaaaaaga aggaccgttt
    44221 ccgccggtcc tttacctgca ttctcacggc ggagattttt cagtcgggaa aagtgaattg
    44281 atccatggtg ctccttactt agcttctcca tcttttgcag aagtactgac aggaatggga
    44341 tatgctgttt ggtcgattga tgcttgggga tttgaagaac gcggaggtat ttctgaaagc
    44401 gagttgttca aacaattttt attaacagga aaaacgttat ggggaatgcg tatttatgat
    44461 gtgatcagct tgatcgatta tttggagaca agggaagaca cagatactca acggctcgca
    44521 acgattggtc tttctatggg aggcttatta agctggtggg tgacagcatt ggattctcgt
    44581 gtcaaagttt gtattgatct agcggcacag gtggacatcg aaatactttt gctacatcgc
    44641 cgcctagatc atcatgggtt ttattactat gtgccaaatc tattgacagc ttatacaacg
    44701 ttagcaatcc aagaaaaaat cgctccgcgc cctcgtctta gcttagttgg aaaaaacgat
    44761 acgatgtgct tggacgaagg cgtactgaag ctgagaaaag ggctggacaa aaagtatcaa
    44821 tcaatgggta gtccagaaaa cttttcttct ttttctttaa caggcggtca tatggaaaca
    44881 caagaaatga gaaatatttg gaaacaattc ataagggagc atttatgagg atgaaagaca
    44941 aactgataat tggaaagaat gctatagata ccccgacgga ttttgaaact atccaagaag
    45001 gaatcgatta tttggcaggc ctgccggata gccatccaaa ggtcttgata gtaaaagaag
    45061 gaagatatga tgaatatata gaaagcagat tatccaattt taaacttgtg ggagcaggaa
    45121 cagtagttat ctccggtaat cgttttgcaa aacaggagta tcttgacggt agccagttag
    45181 ggactttccg aagtgctact tttttcttag aaggatcgaa tgtcgtatta gaaaatcttc
    45241 acatcgaaaa tacagcaggt ccaggagaaa aggtaggaca ggctgttgct ttattcaatt
    45301 caggagatcg cgtatcttta aaaaactgtc gactatctgg ttatcaggat accttatgca
    45361 cgggtccgtt gcctgatttg caaaaagatg gtactccttt ttgtacaccg gcttctgcca
    45421 atcctgagta ttgtcgtcag acctatgaat attgctggat tgaaggaacg gtggatttca
    45481 tatttggtgg ggcagatgcc gtttttcatc agtgtcatat ccatagctta gccagtaaaa
    45541 atcctggata catcacagca gcatctacgc cgaaaaatca aaaaacaggg tatcgttttg
    45601 aaagctgtac cttgactgca gaacctgata ctagaaacgt ctatttagga agaccgtggc
    45661 gtccgtatgc aaatgtctta tttgaagcgt gtaagatagg tgggcatgtt cacccaactg
    45721 gttgggataa ttgggatgac aagaaaaatg aacagactgt caaattctct gaacgtaata
    45781 acaattatga aacatcgatc aaaagacctg aatggataca tttagaaaag cagggggttc
    45841 agaaatgaaa agaaaatggg aactattgct aggaatggtc ggtggcagtc tatctttgat
    45901 tttctttggc gggttagcag ttactttaag taatatgtct gcgtcagagt ttaaaaaaag
    45961 ttatcagtcg cttgctgtag atcattcaac tttgtcttta gaaaatacat ttggattatt
    46021 acaggacatg actggtctgt ttgccgttgt gttgtttatt tcacttgctt ttttagcagt
    46081 agcattgttt ttgactgcta aaggaaaata cttaacaact gccactggtt tgtattttat
    46141 aacaggattc atattgttga ttggcactca gtttattgcg tttccttttg cattttttta
    46201 tttcgcagct ggggcattca gtttatatcg agtaagaatg agaaaaggag cctgaatcat
    46261 gcagactatc aaagtgaaaa atcctatttt aagaggattc aatccagatc ctaatatatt
    46321 aagagtgaaa gagcggtatt acattattgt ctcctctttt gaatggcttc caggaatccg
    46381 agtatatgag tcgaaaaatt tagtcaactg gtcacataca acggatattt tgaccactca
    46441 agtatctttg caaggaaatc ctacaaatgg aagtatatgg gcgccacaaa tcagttatgc
    46501 tgatggattg ttttatcttg tttacacaga tgtcaaaagt gcaggccgtc cgtttaaaga
    46561 tgtccacaat tatttgatca ctgcatctga gatcacaggt ccttggtccg aaccaattta
    46621 tttaaatagt aacggctttg atccttcttt gttccatgat cttgaaacgg gaaaaaaatg
    46681 gcttgtcaat gaactatggg attatcgtct ggacacaccg aataaatcca gcggtatcgt
    46741 attacaagaa tatgatgcag agaagaagaa gcttgatggt cccatctata aaatatttgc
    46801 aggtacagaa ttagcgaaaa cggaggcacc acatttgtat tttcgtaacg ggtattatta
    46861 tttgatgacg gcagaaggcg gtacaggaag aggacattca gttacagttt gccgagcaaa
    46921 gaatattact ggtccttacg agcttgatcc tggttttcct atgctgacag ctagtgacaa
    46981 acctgcttct acattgcaat gtacaggaca tgggagctta gtacaaaccc cgtcaggaag
    47041 atggtacatg acatatcttt gtaccagacc attaaacggt gcggctattt tgggaagaga
    47101 aaccgctatt caagaagtgt attggacgtc cgacgattgg ttaagactta aagatagcca
    47161 gacaactccg atggaagaaa taatgattga gacaaatgaa gaggtacaac aagaaaaaga
    47221 tcatcagttt atggatacat ttgaaggaga gctaaagaag aactggaatg ccagacgcat
    47281 tttgccaaat gctgattggt gtgatacaaa atgtagacca ggttttttac gtctgatttc
    47341 cggtgaatct cttcaatcta ccttcgaaca tcatttgtta gctattcggc aaacggattt
    47401 tacttttgat gcggagacag catttgaata catgcctaat aattttaatc agatggctgg
    47461 actggtactg tacttaaatg aatccaatta tatttattgt tatgttactt ggaatgagga
    47521 caagggaaaa tgcctacgta tgatagaatc agaaaacgga gtagcacaaa tagaagattg
    47581 gacgattcca ctcacagaaa agaagacttt tttgaaagtc actgtaaaga aagagacagc
    47641 acagtttcat ttgaaagacg tatcaactga agaatggaag aaagtaggtc cgcaaaaaaa
    47701 catgtgtata ctctcaggag ggtttactgg aaattttatc gggatagcag tgcatgatct
    47761 aaataaaaaa agaggaagtt atgctgattt tgagtttttc aagtatgatg gaaaagatca
    47821 tctgtaattt aattctttaa taaatgaggt tcactaactt attttcacta gttagtgaat
    47881 ttttttgttt gtatatattg ttatgtaaaa aaagttatca atcttatgca tcaatgtttt
    47941 tagattattt tttgtttttt atctgtcaag ataatgcaat aaaaagccaa cattgtgaat
    48001 ataaaaacaa gaaaaaaaga gttataattt tgaaaacgtt tactagaaga ggtaggagga
    48061 attcaaatgc tttcacaaaa tgctgttaca gcaaatacaa taaaaaaaga aaaaaaggaa
    48121 tttgggattt ccgataagat aggctacatg ttcggtgatc taggtaactg ttttatttta
    48181 ggtttagtca atagtttctt gatgatttat tatacgaatg ttcttggcgt ttcaggggca
    48241 atcgtaggta cgttattctt gatttcgaga attttggatg cgtttgctga tgtgatggtt
    48301 ggaagattat gtgatgtctc agagttaaca gaaactggcc gatttattcc ttggatcaga
    48361 aaaatgaagt atccattttg cttagtgact gtcattttgt ttttgccatt cgtccaacat
    48421 cttccaatga cggtgaagat tgcttatatt tttgtttcat acattgttta tgggattttt
    48481 ctctcaacaa tcaatatccc gtatggagca atggcagcag caattagctc aaatcctaat
    48541 gaccgcacct cgttgtccac gttccgaagc attggttctg cgattggcgg atcaactaca
    48601 ggattcttca ttccgatttt aatgtatacc cataacaaga gtggacaaca agtcgtttca
    48661 gggaatcatt tcttttggat ttcaatcgga tgtgctgcaa tagcatttgt cgcatatatg
    48721 ttaacttgta aattgactac tgaaagagta agagttgtca aaaacgaaaa agtatctgct
    48781 tctcagttgg taaaaggttt gttagctaat cgagcactga ttattttagt cattgttgac
    48841 attttcattg tgatcaatca gattttagct gggacgaata tgacttattt attcaatgat
    48901 tacttccata ataaacaagc aatgtctgtt gctcttttat ttacttacgg aacagtagta
    48961 gttttagcac catttgctac aaagctgaca aaattatttg gtaaaaagga agcaagcgta
    49021 tttgcgttac ttgcttcttc atgtatgtac ttgctgatgt atttccttca tataacaaat
    49081 gcatgggtat atctgattct tttatttatc gctactttag gatctggttt attcaatttg
    49141 atggtctggg cattcattac tgacgtgatt gattatcatc aatataagac aggcttaaga
    49201 gaagatggaa cagtatatgg agtaaattct tttgcgagaa aagtaggaca agcatgtgca
    49261 ggagcggtag gcggatttat gctggcactc attggttacc aatcgtctac aacaggtgga
    49321 gccatccaat cagttttagt acaagaaagg atttatacga tggcaaactt gttaccagca
    49381 ttctgcttat ttgtatccgc aatcattttg ctagtaggtt acccactgaa tcgttcaaaa
    49441 actgtattta ttggtgaaga attgaaaaaa atcaatgaaa gatagggaga aacgtattgc
    49501 ggacaaaaaa agggattatc aatgctttga actttaaaac aaacgacact caacaagatg
    49561 atacaataat actgcaaaaa gcaatcgatc aaggtgcgaa agaacactta cctgtattta
    49621 ttccaaaagg catttattta gtcggagccc tttttttaaa agataagagt catcttatct
    49681 ttgaagaagg tgcagtcctc aaggggagaa cagatatcga agcatttcca gaaatcgata
    49741 cacgagtagc cggcgtagaa atgaaatggc cagcagcgat tttgaatgtt ctctcggcga
    49801 aagatattct tatagaagga aaaggaataa tcgacggtca aggagaccat tggtgggagc
    49861 tgtattgggg aaaagatcaa aaaagcggga caagagctga atacgatcaa aagggacttc
    49921 gttggattgc ggattatgct attaaacgtc cacgcgcttg tttactgtat catgcagaac
    49981 atgttgttgt tcgtgatttg atttttcaga aatcaggttt ttggaacttg caaatcactt
    50041 attctaacga tgtattagta gaaaaagtaa tcatccgcaa caatgatgga ccaagtacag
    50101 atgggattga tattgattct tcaacaaatg tgcgtgtcta tgaatgtgat ttggcctgtg
    50161 gtgatgattg tattgctatt aagtctggca gagatggcaa tggtgcaaga gtcaatcgaa
    50221 aatcatcaag aatcgaggtt gctagatgta aaatccgttc aggatacggt gtaactattg
    50281 gtagcgaagt tagtgctgga gttagtgacg tatatattca cgatatcgat ttttttcagt
    50341 cagactgtgg tattcgaatg aaatcttcaa aagaaagagg gggagtgatc gaaaatatca
    50401 gggtagaaaa tctgaatatg attgatgtac aatttccttt ttcttggata atggactggc
    50461 ataatgaata caatagaaaa aatagcaatg accttgctca aatgccagaa agttggcaag
    50521 cagtggctga agaaatacct gaatcaaagc aaatgacgaa agtcaaagac atacacatca
    50581 aaaacgtaca ggcatgcctt tctccaggtt actcacttcc ttcccgagct tttgatttag
    50641 tagcatttcc tgaaaagcct atagaagatg tctgcttttc tcattgccaa ataactgcaa
    50701 aagaattcgg gcgaatcgaa gcagtacaaa acttatgttt caaaagctgt gatttatcta
    50761 tagaaactgg caacacagct gcaaacaata cttttgacaa tcgttgaaat tataataagg
    50821 tcaagcttaa ataatatttt agcttgacct ttattttttt taatgatata ttaaacaacg
    50881 ttgtcgcgct tcattgaaac attttatgaa aattccaaaa aagagttgac acatgttttt
    50941 agacgtgata agataactaa gtcgttaaaa agaaccactt gcgaagcttg attctatcga
    51001 aaaaaacttc aaaaaagttc ttgacaaata acaaacgata agttatgata aatgagttgc
    51061 tgaaagattt cgaaaaacga aatcgaaaaa aacttttaaa aaagagttga caatcgtttg
    51121 tctctctgat atgatataaa agttgctacg gcagccaaaa atgaatcggg aaacactctc
    51181 gatgaagtag acctttgaaa actgaacaaa gtaagacaaa ccaaatgtgt agggcgtctt
    51241 gattcaattc aagacaa
//
LOCUS       DAFLWC010000011        44829 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.011, whole genome shotgun sequence.
ACCESSION   DAFLWC010000011 DAFLWC010000000
VERSION     DAFLWC010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44829
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.011"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(2..1012)
                     /locus_tag="L1V17_000597"
     CDS             complement(2..1012)
                     /locus_tag="L1V17_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBN1235384.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(1192..1536)
                     /locus_tag="L1V17_000598"
     CDS             complement(1192..1536)
                     /locus_tag="L1V17_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBN1235385.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(1529..1963)
                     /locus_tag="L1V17_000599"
     CDS             complement(1529..1963)
                     /locus_tag="L1V17_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HBN1235386.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            2101..2838
                     /locus_tag="L1V17_000600"
     CDS             2101..2838
                     /locus_tag="L1V17_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1235387.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            2831..4042
                     /locus_tag="L1V17_000601"
     CDS             2831..4042
                     /locus_tag="L1V17_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1235388.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            4246..5028
                     /locus_tag="L1V17_000602"
     CDS             4246..5028
                     /locus_tag="L1V17_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HBN1235389.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            5098..5760
                     /gene="trmB"
                     /locus_tag="L1V17_000603"
     CDS             5098..5760
                     /gene="trmB"
                     /locus_tag="L1V17_000603"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBN1235390.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(5858..7612)
                     /gene="ade"
                     /locus_tag="L1V17_000604"
     CDS             complement(5858..7612)
                     /gene="ade"
                     /locus_tag="L1V17_000604"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBN1235391.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNNQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            7744..8673
                     /gene="tadA"
                     /locus_tag="L1V17_000605"
     CDS             7744..8673
                     /gene="tadA"
                     /locus_tag="L1V17_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HBN1235392.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            8630..9679
                     /locus_tag="L1V17_000606"
     CDS             8630..9679
                     /locus_tag="L1V17_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HBN1235393.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            9676..9954
                     /locus_tag="L1V17_000607"
     CDS             9676..9954
                     /locus_tag="L1V17_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBN1235394.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            9929..10399
                     /locus_tag="L1V17_000608"
     CDS             9929..10399
                     /locus_tag="L1V17_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBN1235395.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            10416..10718
                     /locus_tag="L1V17_000609"
     CDS             10416..10718
                     /locus_tag="L1V17_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235396.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            10735..11106
                     /locus_tag="L1V17_000610"
     CDS             10735..11106
                     /locus_tag="L1V17_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HBN1235397.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            11078..11437
                     /locus_tag="L1V17_000611"
     CDS             11078..11437
                     /locus_tag="L1V17_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235398.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            11609..12616
                     /locus_tag="L1V17_000612"
     CDS             11609..12616
                     /locus_tag="L1V17_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBN1235399.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            12641..13825
                     /locus_tag="L1V17_000613"
     CDS             12641..13825
                     /locus_tag="L1V17_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBN1235400.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(14262..15845)
                     /locus_tag="L1V17_000614"
     CDS             complement(14262..15845)
                     /locus_tag="L1V17_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBN1235401.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIVLVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(16423..16566)
                     /locus_tag="L1V17_000615"
     CDS             complement(16423..16566)
                     /locus_tag="L1V17_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HBN1235402.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(16789..17268)
                     /locus_tag="L1V17_000616"
     CDS             complement(16789..17268)
                     /locus_tag="L1V17_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBN1235403.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(17341..17625)
                     /locus_tag="L1V17_000617"
     CDS             complement(17341..17625)
                     /locus_tag="L1V17_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235404.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(17703..17897)
                     /gene="ssrS"
                     /locus_tag="L1V17_000618"
     ncRNA           complement(17703..17897)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="L1V17_000618"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(17969..19255)
                     /locus_tag="L1V17_000619"
     CDS             complement(17969..19255)
                     /locus_tag="L1V17_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBN1235405.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            19393..20064
                     /locus_tag="L1V17_000620"
     CDS             19393..20064
                     /locus_tag="L1V17_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBN1235406.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            20030..20518
                     /locus_tag="L1V17_000621"
     CDS             20030..20518
                     /locus_tag="L1V17_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HBN1235407.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            20531..21478
                     /gene="prmA"
                     /locus_tag="L1V17_000622"
     CDS             20531..21478
                     /gene="prmA"
                     /locus_tag="L1V17_000622"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBN1235408.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            21479..22243
                     /locus_tag="L1V17_000623"
     CDS             21479..22243
                     /locus_tag="L1V17_000623"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBN1235409.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            22476..24689
                     /locus_tag="L1V17_000624"
     CDS             22476..24689
                     /locus_tag="L1V17_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBN1235410.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            24700..25146
                     /locus_tag="L1V17_000625"
     CDS             24700..25146
                     /locus_tag="L1V17_000625"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBN1235411.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            25317..26576
                     /locus_tag="L1V17_000626"
     CDS             25317..26576
                     /locus_tag="L1V17_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HBN1235412.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(26665..27612)
                     /locus_tag="L1V17_000627"
     CDS             complement(26665..27612)
                     /locus_tag="L1V17_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBN1235413.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            28006..29298
                     /locus_tag="L1V17_000628"
     CDS             28006..29298
                     /locus_tag="L1V17_000628"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBN1235414.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            29313..31082
                     /gene="aspS"
                     /locus_tag="L1V17_000629"
     CDS             29313..31082
                     /gene="aspS"
                     /locus_tag="L1V17_000629"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBN1235415.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            31191..32066
                     /locus_tag="L1V17_000630"
     CDS             31191..32066
                     /locus_tag="L1V17_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBN1235416.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            32332..34215
                     /locus_tag="L1V17_000631"
     CDS             32332..34215
                     /locus_tag="L1V17_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBN1235417.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(34290..34574)
                     /locus_tag="L1V17_000632"
     CDS             complement(34290..34574)
                     /locus_tag="L1V17_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBN1235418.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(34564..35298)
                     /locus_tag="L1V17_000633"
     CDS             complement(34564..35298)
                     /locus_tag="L1V17_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBN1235419.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            35427..36050
                     /locus_tag="L1V17_000634"
     CDS             35427..36050
                     /locus_tag="L1V17_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBN1235420.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            36242..37363
                     /locus_tag="L1V17_000635"
     CDS             36242..37363
                     /locus_tag="L1V17_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBN1235421.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            37370..40498
                     /locus_tag="L1V17_000636"
     CDS             37370..40498
                     /locus_tag="L1V17_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HBN1235422.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            40517..43711
                     /locus_tag="L1V17_000637"
     CDS             40517..43711
                     /locus_tag="L1V17_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HBN1235423.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(43857..44564)
                     /locus_tag="L1V17_000638"
     CDS             complement(43857..44564)
                     /locus_tag="L1V17_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBN1235424.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT        14383 a         7961 c         9406 g        13079 t
ORIGIN      
        1 tttattttga tgaatcagtt gtttcttcag ttgaagattc ttttgttgaa tcagttgatt
       61 ttgtgtcaga actctttgtt gaagctgtag tttcacttga gtctttcgta cttgatgaag
      121 ttgttgtgaa tgcactcaac acattttcaa aggcatcatc tttgattttt acatttgcat
      181 cttttaattc ttcaccgatt actttagttg tgaatgcatt gtcacttagt ttagtttcag
      241 tagcgatatc ttttagttga tctttgtatt tatccatgtc attgccttta ttttggtttt
      301 tcaccatttt gacaacgtag tattctgtcg cataagaagt aggatttgtt gtagtaataa
      361 catcggagat ctcaccgtct ttcaatttga aagctgcttc ttttacttct gcaggaatag
      421 ttgttgtcgt tgagtcgaat ttaactttac cgccatcttc ttttgtctct gtatcagttg
      481 atttgtcttt ggctaattta gagaaatcat ctccatcatc cgctgatttt ttcacatctt
      541 ttgcttcatc ttcacttgat aatttgatga tttgtgcttc tacttctgga tggaaagatt
      601 tccaagcagt tttcaaatcg tcatctgtaa tatctacgtg agctttcaag ccagcttcaa
      661 aagctaaatt gttacgaata tattctttat aagtatcttt cgtatatcca gcagcttcta
      721 attgtgattc aaaagtatca cctaatgatt tcgcttgttt gtcgtattct gcatccactt
      781 gcttatcggt tactttatcg ccatatttgt tattgaatac tttataaatg atcatccgtt
      841 gtactaagga ttggttcgat gattcaagtt ttgcttcatc atagaaatca gatacagtga
      901 tcgttccgcc tttcatcgtt gcgatatctt tattagtatc gcctgaacaa gctgctagag
      961 ttaaaacagc caacgcacta gtagctgcca aaataattga tttttttttc attaaaattt
     1021 gcactcctgt aattagttat tatttttata tattaactat accatatccc atttccttta
     1081 aaaacgttgt cgtggtagtt tcaaacaaaa ttcaaaattt catcacattc ctaggaaata
     1141 cgcaaacttt tctcacttat atagttaaat ctgttgagaa aataatcatt attatatttg
     1201 ttcaggatac tctggcagat cagcttttag tttttctact tgttcattga tttgtgtgat
     1261 acgtggttcg gcttggaatt taaaatcttc gatatctttt ttgattgctt cttggaaagc
     1321 aggaatcaca gattcagctg tttcttttgt ttcgatcaat gcgcttttaa aatgattcag
     1381 gctgttattt aaatcatttg tcagagttgt tgcttcttcc aattcttcga tcagtttctt
     1441 tcttgtttca ttcccgctcc tgggcgccaa taacagacct ccgacagtgc cagcagcagc
     1501 tccaaataac agtcctttga aaaagttttt aatcatcgca ggacacctgc tttacgattg
     1561 tttcttgaat agcttttagt tcttccgatc cataactatc ttgatgattg acaaagtgaa
     1621 tagaaaaatc atcctctttg ctgtagcgag ggactaaatg gatatgtgaa tgaaaaacag
     1681 attgataggc tagttcacgg ttgttattca agatattaag acctttcatt tctggaaaag
     1741 ctttttccaa tgcttgagca atcttaggca cacgcgaaaa aacctctcct gcaagttcgg
     1801 gatcatattc aaaaatatct gctacatgac gtttaggcac aactaatgtg tgtcctttcg
     1861 ttgcttgaga gatgtctaaa aaagcataga ccttgtcgtc ttcatatatt ttatagcttg
     1921 ggatttcttg attgatgatt ttgcaaaaaa tacagttttc catataaaac atcctttcta
     1981 taaagaataa atacttcagc ttaactttac cataagttaa agctattgta aggaaaaaaa
     2041 caaaataccg tcattttctt cgtggtataa taaataaaaa taaatggcgg aggaaaaaga
     2101 atgagtttaa ttatcgatca tgtcacaggg gggtacggac atctccctgt gttaaaagat
     2161 atcagtttcg atgtacagcc tggagagata gtagggttga ttggactgaa cggagcaggg
     2221 aaaagtacga ccatcaagca cattatcggt ctgctggaag cttcaaaagg aacgatagaa
     2281 atcaatcatc tatccttaaa gaaaaatacg gaagaatatc gcaaacaaat tgggtatatt
     2341 ccagagactc cttctttata tgaagaattg acattgagag aacatatcga agtcactgcg
     2401 atggcctacg atatacctat ggatatagca atgaaaagag cagaaaagtt gttggagact
     2461 tttcggttat ctaatcgtct tgactggttc ccagctaatt tttcaaaggg aatgaaacag
     2521 aaagtgatga tcttatgcgc ctttttgatc gagccttctt tatatatcat cgacgaacca
     2581 tttttaggct tggatccact agctatcaat gcattgcttg aattgatggt agaaatgaaa
     2641 aaagaaggag ccggtatttt gatgtctacg catattttag ctactgcaga aaaatattgt
     2701 gatcgttttg tggtcttaca taacggagag atacgagcag acggttctct tgagatgttg
     2761 agaaaagaat ttcagctgcc ggattcttct ttggacgaaa tctatattgc tttaacaaag
     2821 gagcaggcac atgagtagtt tttttcaaaa acgtttagca agacatcaaa agaaaatgat
     2881 gaaatatatg cgttatgtat tgaacgatca ttttgtttta gtttgtcttt tcttgattgg
     2941 cggtgtggga ttatattatt ctaattggtt gaaaaccctg cagccaccgt ttgcaattgg
     3001 agggctcata atctctgtat tttggatgct ctgtttattc gtgggtaaga tggctacttt
     3061 tgcagaggca gcagatattg tttttttact tcctaaagaa aaagaaatgc aaacctattt
     3121 ggaacgagct tttcgctatt cttgcatttt tccgttgatc tttttgatat tggcatgcgg
     3181 attggccatg ccattagtgg tggttagtac ggagcaatcc ttttcgatgt ttttcgtcta
     3241 tctgatcata ttatggagtt tgaaattcag tcatctgcaa atcaagagag cagaattgtt
     3301 tcgactagat caacaagtta ttcgttattg gaaattaggc tggttttttt cttctctgat
     3361 ctttttgttt ctatcatttt attggctaat atgggcagga atagcaggtg cattagtaca
     3421 ggcaagtcta tattactggt ttttgtggaa gcaacaagaa aaaggattgg attgggagaa
     3481 aatggtgcat gtagaagaac ataggttgca tcagatctat caatttatca atttattcac
     3541 agatgttcct gaaattacgg caaagatcaa aagaagacgc tatttggatc ctatattgac
     3601 tcatattaaa agagaatcaa aaaacactta tctttacttg tttgcaagaa gattggcaag
     3661 aggttctgat tttagtggtc tttatttccg attagtaatt ataggtgggt tattgattgc
     3721 cggagtagtc gacttttatt ttagtctgat tatcggtttc ttatttttat atttgatcgg
     3781 tttccaactg ttacctttag cgaaccagtt ccgctatatg gttctcgttc agctttatcc
     3841 aatccataag aatcagaaga agcaggcgat tcagtatcta ctcacatggg tattaattat
     3901 cgcgtcggtt atttttggtt tgattgctgc agtcgtatta gatgggcagc agcgatgggt
     3961 tccgctagcg gcttatttga ttgttactat gctctttgtt aaactatatg taccaactcg
     4021 tttgaagaag atgtcagact gaaaacaaag ctgtgtaggg taaaaatgag aatgaaaaat
     4081 agagcgttga cagtaagaat gctgttcgtt ctattttttt tgagaaaagc tggttttttg
     4141 aatggcaatt aaatgaaaaa gaacgtatat gtgcttgacg tgtagtgttc aggcgactag
     4201 aataataagt actgcaaaac aaagagtaag aggacgggag aatgcatgat ggagtttcag
     4261 ttagaccaag agtggcggtt acgtcccatc aaaggcgaca caggaaaaac atacataggc
     4321 atgcgtgatg aggacaaagt ctttattaaa cgaaacacga ctccgatgtt ggctgctctt
     4381 tcaagggaag gaattacacc aaaacttgtt tggacaaaac gaacggggaa tggcgatact
     4441 ttgacagcac aagagtggct ggaaggtcgc ttgctgactc ctaatgagat tggtcaaaga
     4501 aacgacgtga ttgatgtttt gtaccattta catcattcaa attctcttaa aaccatgctg
     4561 acccgtatcg gtggtcgtgt catgacgccg gagaagatgc tgcaaaaata tgaaaaagaa
     4621 ttaccggaag aactccagaa aaatcaattt ctgcaaattg tccatcgttt tcttcgtgag
     4681 cagatcccgt caatagataa ggaaaactta tcagtagtac acggagatgt aaaccatcgt
     4741 aattggttag tatgtaaaaa ttatttatat ctagtcgatt gggattcaat catgtttgca
     4801 gaccctgcgg tggatattgc aacgatttta ggaaattatg tgccactgtc tagctggaat
     4861 cagtggctga tcagttatgg catacgcccg actgacgaaa tgcttgaaaa atttcattgg
     4921 tatgcggcca tgaatttgct ccaagaaatc accagatatt gcaaacgtga agatcatcga
     4981 cggatgaacg aagaaatttt acaattaaaa cgaattttca gtggctgagg tttggcccaa
     5041 actctgcgga gatttggcca gaccttttta attagaggaa aggaatggag ataaataatg
     5101 cgtgtccgaa atcgtccggg agcagcggaa atgttagcgg ctcacccgaa ttttgtaatt
     5161 agtgatccaa cattgtggaa gggaaaatgg aatgaattgt ttgaaaacga tcatccaatc
     5221 cacattgaga ttggtatggg gaaaggccag ttcatcactg gaatggcaaa agcccatcct
     5281 gaaatcaatt atattggagt agaaatgcag gtcagtgttg tttcgattgc actagacaag
     5341 ttgatcgaac aaccgcttcc taacctgaaa cttctacatg tggatggatc agcgttgaca
     5401 gagtatttcg ctgacagcga agtagatcaa atctatctga atttttccga tccatggcca
     5461 aaaaaacgtc atgaaaaacg gcgattgaca tataagactt ttcttgctgt agatgaacag
     5521 attcttcgtc caaatggaga aatccatttc aaaacagata atcaaggatt gtttgagtat
     5581 tctctggcaa gtttttctca atatggcatg atcctcaaac aggtatggtt agatttacat
     5641 caaagtcaat ttgaaggcaa tattatgacg gagtatgaag aaaaattttc ttcaaaaggt
     5701 caacgtattt atcgagtaga agctcaattt caagataaga ccaaaaagaa aagtctgtga
     5761 aactaacttt ctgctttcat aaaaacatta atatccataa ataaatccca gaaaatgaac
     5821 attacagatg taatgtattt tctgggattt atttgattta aaatgtattt atttcatcgg
     5881 tttttccaca aggtggaatc aattggaagc gagaaaatga aaataatcct ttgtcggtga
     5941 tcttcaattc gggtatgaca gataatgtta agaaagaaag tgtcaaaaaa ggatcaaagg
     6001 ttttagctgc tcctagttga tgtgctttag ttattaattc attcaactgt tcatagacga
     6061 tcgaaaaagg ttcctgtgtc atgattccgc ctataggaag agaaacacaa gctatttcct
     6121 gctgattgtt gacaacggtc atcccgccac ctttttgaat caaaagatta gcagcataca
     6181 gcatatcctc gtcgtttgtc ccaacgacaa ctagattatg cgagtcatgg gcaatcgttg
     6241 tcgctatcgc tccttgtttc agctgaaatc ctttcactat gcctaatcca atgtttcccg
     6301 tttgatggtg acgctcgatc accgcaatct ttaattggtc tttttcgatt gaaggaatga
     6361 atcgttcgcc ttgtcggtcc actttttcta ccaaatcttt agtcactaga ctattcggga
     6421 taatttcgat cacatgggct tgtgaagaag aaagaagcag ctctaacgaa tgtggattta
     6481 atggttgagc gtttagtttt ggcagacaac acgtatatga atttgaatga tcagcaaata
     6541 aatggtcttg gagttgccca gattgaacaa ctaatgttcc cttatagaaa acttcatgaa
     6601 ttggcagctt ggtaagatcg tctgttaaga agaaatcagc ttgataccca ggggcaatcg
     6661 cacctagtgt tttcaaatca aaacattctg ctgcattcaa tgttgccatc tgaatggctt
     6721 gtaatggatc gattccaagt gcaatagctt gacggacgat atgatcgatt gatccttctt
     6781 ttactaaatc attgatcagt ttatcatcgg tgacaaagaa gcatcttctt gaattttcag
     6841 gtgtgatcgc cggtagtagc gatgccagat cttttgcaac ggtcccttct cgaaccatta
     6901 aatacatacc aagatccaaa cgttctttag cttcttttgc agttgtagct tcatgatccg
     6961 tccgaatacc tgctgcagga taaacattta actcttccat gccgatacca gctgcatgcc
     7021 cgtcaatttt tttcttatgc tggtgcatca attggatctt ttctaggatg tctgtttcat
     7081 tatttgctac tgcttgatag ttcatgactt cagctaagcc taaaacttcg ggtttttgta
     7141 aaaaaggggc taattttttt gcatttaaat ttgcaccatt ggtctcaaaa ggggttacag
     7201 gtacacaaga aggtagcata aaaaagatat tcatgagtgt ttgtcttgca tcttctatca
     7261 taaactcaag acctgtactc ccagcaatgt ttcctatttc atggggatct gtcactacag
     7321 tagtaactcc atgaagcaag gatacttttg aaaattcgct tggtgataaa agtgagcttt
     7381 cgatatgcac atggccatcg atgaatcctg gcactagata ttgcccatta gcattatgta
     7441 cgctttttcc ttcgtattca ccgattccta cgatcattcc ttcgcagatt gctacatctt
     7501 tttccatgat ttctttcgta aagacgttga cgatcttagc atgcttgatc actaggtcag
     7561 caggcttttt tttacttgct acttcgatat atttccttaa tgttgtttcc aatggagtgc
     7621 ctcccaagat aaatttttat aagtataaca taaattcggt ttttgccaat atttttttgt
     7681 aaattcattt tatttgaaac aaaaagatca aaaagacgta tgttttttgt ggaggggaga
     7741 ataatggaaa taaaacgatt atcggatcaa atgataagtg aaagttttgc caaacatgcc
     7801 caagacgtat atatattgcc agcttcagaa gtattttaca tctattttcg ctatggaaaa
     7861 aaacgaacat tctggaagaa agtctcttcg gcagatggac agcaactgat ctcaagattt
     7921 aagtatttgg gacagatgga tatcggagaa aaaagaaaag ctcagttagg tgcatttact
     7981 tattctttag aaaaacagga agttcgtctg cggttgtctt ctgtaggaga ttaccttcaa
     8041 cgagagagtt tagtgattcg gctattatac ggtacttttg aaacacccca tcgttgcttt
     8101 agttctcgag attttgcaac tattttacag aaaaccgtca gacgtggatt ataccttttc
     8161 agcggaccag tcggatcagg caagacttct ctaatgtatc ggttggcttt ggaagaaaaa
     8221 ttgcaagtga ttactatcga agatcctgta gagatagaag aaccgttttt tctgcagcta
     8281 cagatcaatc cgaaaatagc acagacttat gatacacttt tgagactcgc attacggcat
     8341 cgtccagact tgctaatcat tggcgagata agagatgaat caactgcaca tgctgcggta
     8401 agagcagcac taacagggca ccgggttttt gcaaccgtac atgcacgcaa tcttgaaggt
     8461 acattggtca gaatccatga actgacaaag aaaaaagaag agctatctga atgtttagct
     8521 ggtgtcattt atcaagaact tttggaagat gccaatcacc atccttctgt tttatggagt
     8581 tatcaattta tggaggaaga atcagtaaaa aaatcatggg aggaaagtta tgaagaagct
     8641 caggaaaata tttggcagtc agaactattc taaaggatta acaagaagcc agcaaaacca
     8701 gtttgcacaa accatgggag aactgctttt atctggtttt agtctgcaag aatcccttta
     8761 tttattactc acgatccgtt cgtttccacc tgttattttg gcaaatatcc aacatcagct
     8821 aaaggaaggg caagcgttta gtgaggtact ttcgcaaata ggatatggag cagagcaact
     8881 ggtacagatc gagttagctg aacgtcatgg gaatctgccg acaactttgt tggaaattgc
     8941 caaacagttt cggcttgttg aaggatttcg caatgatttg aaaaagctgc ttgcatatcc
     9001 gatgctattg ctcacctttt tgctaggtat cttgtttagt atgcggttgt tcgttttgcc
     9061 tcagcttatt ggttcaggaa tggtcatgca agagcattgg ggtattcagc tgatacaagt
     9121 ctttcattgg tatgttctac tattcatcct agcggttact ctattggctt tactagtaag
     9181 gtatcgtctg atgaagttgt ctcctgttga tcagagtgaa tggataagca gacaattatt
     9241 gattggaccg atatattcct tgtatcaatc ggcttatttg tcactagaga ttggaaagct
     9301 ttttcatgaa ggtttcgaat taaggcaaat catagtctgc ttaaaggaaa cgaaacaaga
     9361 aagtctgatt cagcatcttg cctctaagtt gattcaagga ttggaggcag gtatgtcatt
     9421 ggctgagcag ttccagaatt atcgttttct atcagaagaa ttcagtaaaa ttgttttaca
     9481 gggagaggca aagggaagtt taggtaaaga actgattttt tacagcgaat ggacaagaaa
     9541 acagcttttc aaacgtcttc atcactggat gcattttatt cagccaatca tttttttggg
     9601 cgtagcggct ttgattttat tagtttatgc cgctgtttta ttacctgttt acggaagcat
     9661 agaggaggtt ttgccatgaa aaagagaaaa atatcttatt atagcggttt tacattgatc
     9721 gaaatgctaa tcgtcttact gatcatcagt gtattagtgt tgttgttcgt ccctaatttg
     9781 tcgcgttata ggaatcatgt agaccaagaa agtcgtgaag cgatcatcca gttggtagac
     9841 acacaaaaag agctctatgc gcttcaaaat aatggaagag ttcctactgt ggaggaattg
     9901 ttgaatgaag gctatatcaa acgagaacat gcagaaatct atcagcggcc ttgaaggtaa
     9961 ggttttagca tcaggatata cgttgtttga atcactctta ctgattttat tacttacaac
    10021 gatcctttct tttccagttc tcgcattttc tgcatggaag aatgaattgg cagtctatca
    10081 atttttcggc caatttgaaa aacgaatcta ttctacgcaa aaaatcgcta ttgtgaatca
    10141 gatccaaaca ggcttttatt ggaatagtga agagaatcaa atcatttttc atgttccgaa
    10201 tccagataaa ataaattggg aagtattaga tattcctgat gagattacct tgaaacgcca
    10261 tgcttctatt acttttgctg ctagaaccgg gaatgaaagt tcactaaaag cttatcaatt
    10321 ttattgggaa gaaaaagagc ggacgattac gtatcaattc cagataggga gtggtcgcta
    10381 tacaaaaaga attgaataaa acaggatttg ttttgttgga gtcccttaca gcgcttatga
    10441 tcgcttctgt ctgtgtctac ttagtgagct ttggccagct gtttttgctt caggcagaaa
    10501 agaaaagtgg ggaggaactg ctatttattc gaatgattta tgaagatatc aagacgcagc
    10561 ggatgtatca caaaagacca gagcgaaggg aagaaatgat cccatacgat atccaaattg
    10621 tcgataataa tggagtaatc gaaaaagtgt ttgtcaatat ggagaaagaa gcgatcagta
    10681 ttgaaaaaac aagtaattcc agcatttacg ctgattgaat gtctaattgg actgatgata
    10741 ttgagcagtc tattgctcac attcaatctt ttgattcagc aaaccatcca agtaagtgaa
    10801 tttttgcagc gtaaagatca aaaagagtgg ctaatatttt tagcacaatt agaagaagaa
    10861 ctcaagagca gtcacaatgt ctctgtgaaa aatcagcaac tgcactacac gatcgaggat
    10921 aaacagtata tcatcgaaag atatcaggca atgatacgta aaagaagaac ttccggcgga
    10981 catcaaccta tgttaacaag tatcactgag cttcaattat tggaaaaaga acacacaatt
    11041 tctttttatg tacactttga aaatggagaa gatggatatg ccatatggac aaaaaacgat
    11101 cagtagaaaa tgttataagg gctctatttt attttctgtc ttgcttttat ttcttttatg
    11161 tacgttttta ttgatggcag cattagaaag ctaccgtttg tcaatggatc ttaatatacg
    11221 aatcaaaaat tattatatag caaaaataat gaagcagatg gctttatcgg aacagtctac
    11281 gcttgccgaa agttcggaag gagtttttta ctacacaact ggatctgtaa catatcagtg
    11341 ggtacaacag tccctattct tagaggtgga agtctcaccg tttatctttc ggttcacaga
    11401 agaagtaaaa aatgatacag atactagtac agaatgatgg aatgttcgtg aaaacgccct
    11461 cttttctgtt ataacactgt ttttaataaa aaaatgtttg ccgtttcaca aataaaaaac
    11521 agtgaaaacg attgaaattt tgtcaattgt tcgatagaat taaacaggtg aaaaaattgt
    11581 tataatatat ctagaaatga ggtgcaccat gttaccagaa aaaatggaac aagggtttaa
    11641 tcaaaacctg gaagctattc agcttttaca gaatgcattg ggaacttcct ttttagaagc
    11701 ctatgtcgaa aatgcagaaa atttaataga tgattatcaa gtacgtgtgg tggatggagt
    11761 gccgacaaaa gagacaacgc aacggatcac agctctttat gaagagttga agaaactttc
    11821 tttcgagcca gaagaatggc gcagactgtc tcaattactt ttattgaagg gcagccagac
    11881 agaacatttg caggcgaacc atcaactcac tcctgatagt atcggttttt tatttgtttt
    11941 tcttattgaa caactataca caaataaaaa agcaccggtt aagattctgg atattgcggc
    12001 aggaatgggc aacttgttat taacagttct tttaaaccta tcgaatgcgg ggtaccaaac
    12061 agaaggaatt ggtgtggata ttgatgatac attgttggct gtcgcagctt ctacaagtga
    12121 tttgacacaa gcaaatgttc aatactttca tcaagacggg ttgcaggaat tattaataga
    12181 tcctgtcgat tttgcaatca gcgatttgcc aatcggttat tatccgaatg acgaaaaagc
    12241 aaaagagttt ttaacaagta ccgaagaagg ccatagttat gcacatcatt tattgctaga
    12301 gcaatcaatg aaatatgtga agccggatgg ttttggtttg tttttgatgc cgagtggatt
    12361 tttagaaacg gatcaaagtg aagaaatcaa aaaatggttt aaagaagaag gttatcttca
    12421 aggaatgatt caattgccag atgaattgtt ccgtaataaa caatcgcaaa aaagtatttt
    12481 gatcttacag aaaaaaggac cacaagcaca acaagtaaaa gaagtcttgc ttgtgaaact
    12541 tgcttcatta aaagaaccag agaaggtgac ggaatttttc aacgagttta aaaactggaa
    12601 atcatctgct ctgtaatcat tcaacgagaa ggagagtcat atgtctaaaa caattgcaat
    12661 caatgctggg agttcaagtt tgaaatggca attatatcaa atgccagaag aaaccgtagt
    12721 tgcgaaaggg atcgtcgaac gtatcggttt acaagattct atttttacca tcaagtacgg
    12781 cgataatcaa aaattcgaac aaatcatgga tatcgaaaac cacgaagtag cagtaaaaat
    12841 gctgttagat cagttgattg aactgcaaat tttaagctct tatgatgaaa tcaccggagt
    12901 agggcaccgt gttgttcacg gaggagaaac ttatggggat tcagtagtga tcgatgagaa
    12961 agtaatggac cgcattgctg aattagcaga atttgctcct ttgcataatc ctgcaaactt
    13021 aatggggatc aaagcgttta aaaagatttt acctgacatt ttgagtgtgg ctgtattcga
    13081 tacatctttc cactcaacaa tgccaaagca aaattattta tatagcttac cggtgtctta
    13141 ttatgaagat ttcaaagtaa gaaaatatgg cttccatggc acaagtcatc gttatgtgtc
    13201 ggaacgtgcg gcaaaattat tgaacaaacc gatcgaagaa ctaaaaatca tcacttgcca
    13261 cttaggaaat ggtgtatcga tcacagcagt cgatggaggt aaatccatgg atacttctat
    13321 gggattcaca ccattagctg gggtgacaat gggtacacgt tcaggtgata tcgatccagc
    13381 tgttctccca tatttaatgg aaaaattaga gattgatatt gatgaaatga tcaatgtttt
    13441 gaacaagaaa tctggtctgc taggcctaac aggattgtct agtgatatgc gtgatcttga
    13501 aaagaactat gaaaaagaac atattcgttt agcttatgac attttcgtgg accgcatccg
    13561 aaaatacatc ggcggttatg tgacaacgat gaatggtgtt gatgcaattg tctttactgc
    13621 tggtatcggc gagaatgacg gacatgtacg tagtgaaatc atcaaaggta tgtcttggtt
    13681 tggttgtgaa atcgatccag cgttgaatga attgcgtggt gaagaagtag atatctctac
    13741 aaaagaatca aaagtaagag tattagtgat cccaacagat gaggaactaa tgattgcccg
    13801 tgatgtggag cgtctgcgcg gctaagccaa agcattcgtt aggataaaag atgaaacgca
    13861 tgcaagaggg aattcttgca tgtgtttttt ttgcggagaa gaccgcaaaa tggtaattta
    13921 acttcaattt cccttctttt ttacaggatc ttcttaggga attttgcttg gaaaagtggt
    13981 caaaagggaa aagactggca ttttatttat tgattttcag gaaaatccca atattttatt
    14041 ttcattcatc tttataaggg acattacata tgtaaaaaga aaaaacattt ttagatcagc
    14101 ctcgtgggct gtcgacttta ttcttcgctt tatgtttagc tagaaaaccg atccgaaaca
    14161 ttcattgatc gaataataaa aacttgattt tccacctgta ctttgcctga atcgtgaaag
    14221 cacaggtatg aaaatcaagt tttttgttgc gaaaaaacgt cctagtcaat cagttggccg
    14281 agcggctggc ggctgatctg ctcctgatca ataacgagtg cttcttggaa gtgttgctgc
    14341 aaaaagtagc ggtcatggct gactgctagg agcgttcctt gatagtcttg cagcatttct
    14401 tcaatttctt ctcgagcata gctgtcgagg tgattggttg gttcatccaa aatcaggacg
    14461 ttgatttttt ctaaaaagag tttcagcaac gccaaacgga ttttttcacc accggataaa
    14521 tctttgatcc gtttacccac atcgctttga taaaagccac ttttggctaa ttgccgtcga
    14581 gcgacttctt cgtttccagt caatgtgatg gcgtaagcca gcaaacggct atcgggatcg
    14641 gcaaactgca gctgctgcgg caaataaccg atttgcaagc tactacctaa tttgatggtg
    14701 ccaccgtaag gcttttcctc accgagtaat aatttgagta aggttgattt tcctgcacca
    14761 ttgtcgccga tgatggctaa atgatctcca cgatagactg caaaactgct gtctttgaat
    14821 agtacttgat cagcgtactg ctggtgcaag ttttgaatga tgaaaacttc tttgccagat
    14881 tttccaccat tagacaagct ttgcagccga tttttcgggg gaggtggcgg tttgacgagt
    14941 gtcagtttcg ccaggcggcg ttccagttct ttggcttttt tgaagaagga ctcattgtct
    15001 ccttcatgtg cccactgacg aaaacgacga atcatgactt tcaaccgctg gacttctttt
    15061 tgctgcagtt cgtaattttt tgtcagctca gccaagcgag cttctttcaa gactcgaaaa
    15121 cggctgtagt ttccgggata ctcaatcaat gcaccttctt ccagttccca tgtttttgtg
    15181 gtgacttgat cgagaaattg ccgatcatga gaaacgacca gaaccgattt ttttgtattc
    15241 tgtaaatagt tttccaacca gcgaatactg ttaagatcta aatgattggt cggttcatcg
    15301 agtaaaagta aatcggcatc ggctgctaaa attttggcta aagcgacttt aactcgttcg
    15361 cctccgctaa gttctgttaa ccgtgcttcc tgacggtgtg gaatccctaa gccttgcaag
    15421 atcgctgcaa tccggtcttc taatacgtaa ccgcctagtt cttcaaagcg atgctgcagc
    15481 tcaccgtaac gggccagaca cttctctaag tttgtatctg gttctgtcat caatgcttcg
    15541 tagcgactca tttgctgttt gaggtcctgt atctcagcgg cagaatggag caagtagtgg
    15601 ttgacggtcg cttcggaaac tgtaagttct tgttcgaccg tcccgatctt taagcctttt
    15661 ttgcgactga taacaccgct gtcgacacct tctctgccgg tcaagatttg taaaaaggtt
    15721 gatttgccag ttccgttgat accgactaag acaatttttt caccagcttc aatttgacag
    15781 gataaatcct caaataatgg attcccgccg attgtttttt taatagaaat tgcttgtatg
    15841 atcatgatct ctctccttga gaccactcaa aaaggccatg gttatccatg gcctgtgtta
    15901 tttaaactca gattatcatg agaaaaatac cttgagatgg ccattgattt tacgtgaatt
    15961 caactgtttt ggacaaactt gtcccgtcaa cagcaactgt aaaaccaatt gcatggctaa
    16021 atgcgatatg gtatcgttgg taattttcat tacttgttat tttagtcatg cgcatcatag
    16081 tattttccct ccttcgtgta gttgtctttt ccagtgtacc tgaaagtgtc agaaagttca
    16141 actagcgctg acatttactt aatatttatc gatgtgtaat tctgtcagag agcttttttt
    16201 atctgactga gggtaatgtc tcgtggacca catcattgta ttctgagcta aaccagcgtt
    16261 caggcgaaat catatggtgt ttgataaaaa actttgtcta catgacttcc ttttgccatt
    16321 tgcttaatac cgttgcatta aacagctctt ctctttggaa atctcaccaa catcgcgttc
    16381 aggagtatcg ttgtggttgc aatggcaagc ggtagccttt catcaattct tgaatgattt
    16441 accgaatgta gcacttgcct tctcgcggta cccgaacccg aaataaaatt ttagtttggc
    16501 gataaaatcg gtatccgcca tcgatacttc atattttttc gtatcagatt catcggaaac
    16561 ttccacattg acgaaccaat aagctttggc atgcttaggt cgttttaaac cacaccaggg
    16621 cgactaatcg ccctggtgtt cacttttttt tattttactt gaactcattg actgttttcc
    16681 ctttatttta aacattataa agaccgatga gtgcttgccg cgtcttttgt ttttatcacg
    16741 gttttttgtg caaaaaaacc tgccgatagt tggcaggtcg tctacgtgtt aagctttggt
    16801 gtggtcttta gctggcaatt ggttttctaa atcagttcgg acaacaagca catcgcaagc
    16861 tgcgtttcta ataacatatt cagaaacaga accaataaat aaacgttcta cagcattcaa
    16921 tcctgtggct cctaacataa tcaaatctac ttgattatct tctgggattt ctctggcaat
    16981 aatttgtttt ggtgagccat attctacgac agaggttaca ttattcaagc cagctttctt
    17041 cgcattgctt tcataatctg ccaatgtttg ctttgccatt tcagtagctt gttctgcaag
    17101 cattccatca aaggatgaaa cggtttggaa agaacgtgtg tcaatgacat gtgctaatag
    17161 aagttctccg ttatttcgga tagctacatt gaccgccttt ttaaaagcta attcagcttc
    17221 atcagaacca tctacggcaa ccatgatttt tttgtattgt tgtaacataa gcattcactc
    17281 ctcaagtcaa tcgtattgta ctcttttatt gtagaacact ttagggaaaa agagaattat
    17341 ttactgcttt ggttcagcaa ttttttttgc aaatcggata ctgaaggtgg cagaaacaat
    17401 aattacgatc agtaaaaaga ccaaggcaat aaagcgttga ttgaaaaaag ctgttaaaat
    17461 acccattacg cctaaaacag catatgcagc tccgtaaaat tgtaggaatc cttgattttt
    17521 atcatttttg ttgatcaata caaaaaagat atcctgttta ttaaataaat aatagctaac
    17581 gaataataat actaaagtgg cgataatcat taaaatccta atcatgaaca aatcctccaa
    17641 aataagcaac aaatagaaaa agcaatttgc caagagcaaa ttgctttatt ctttaaaaga
    17701 tggtaatctc cgttaatgcc gttgtttgtc ctgtagtatt gatcccgcga attcaagcag
    17761 gtgggtccca tggtcgtagc ttcgaactac caaatgataa ggcatgttac cagcagtgac
    17821 acaagacggg tcccaagata tcaataaaaa tgttcggtca acacacaaag aggacaattc
    17881 gaacatcaca gatttcccac ctctatagta gcatatgaat ttaaaaagag caatgagaga
    17941 gctcgcagaa acagaaccgt tttcttgtct agttttttgg aggatgcttt ttccactctt
    18001 ttatacggta atactgttga cccagagcct gttcatattt ccctgtatct tttggctgat
    18061 aatactgagc attcttcagt ttatctggta aatattgctg attgacccaa gcctgatcaa
    18121 aatgatgagg atactgataa cccacgccac ggttgagtga tttcgcacct ttgtaatggc
    18181 tatctctcaa atgatcagga acatctccag ctttgccctc tcgaatatca gcaagtgctg
    18241 catctaatgc catgtaggca gaattggatt ttggcgacaa gcaaagatcg acgacgacgt
    18301 ctgctagtgg gatacgtgcc tcaggcaatc ccaatttttc agcagctaat acagcgttca
    18361 ctgtacgagc cgcagcagca ggattaccta aacctatatc ttcataaccg ataaccatca
    18421 gacgccggca aatacttgcc agatcacctg cctcaactaa acgggcgaga taatgaagtg
    18481 cagcatccac atcacttcca cgaatcgatt tttgaaaagc cgaaataacg tcataatgag
    18541 catctccatt tttgtcatgg gtaagagctt ttctttggac acattcttca atgatcgaca
    18601 gtgtaagatg aatccttcct tctttatctg aaggagtcga tagtgtagcc agttccagcc
    18661 cattcaatgc actccgcaaa tcgccgttcg ttgcacgcga aaggtgaaga agagcatctt
    18721 cgtctaactg gattgcttgt tgtccaaggc cgcgttcttt atcccttaaa gcatgttcga
    18781 ctgccaactg gatgtcttgt tctgttaatg gtttgacttc aaagatctgt gtacggctgc
    18841 ggatcgctgg attgatggta atataaggat tctcagtagt cgctccgatc aagatgattc
    18901 ggccactttc taaatgagga agcagaaaat cctgttttgt tttatctaat cggtgtactt
    18961 catccaataa gaggatcact gtaccactca tttttgcttc ttccgctaca acttgtagat
    19021 ccttttttga atctgtagcg gcgtttagca tgcgaaatgc ataattagta gagccggcga
    19081 tcgcacttgc gatactcgtt tttccagtac caggaggtcc atatagaatc atggaagaga
    19141 gcatgcgagc atcgaccatg cggcgtatga tttttccttc cccgactaga tgctgctgac
    19201 caacgacttc atcgatcgtt cgaggtctca tgcgataagc caatggctgt tgcataggat
    19261 tttcctcctt cttgttttta cgtcccttaa ttatatcata tttagcaaga tgcctagaaa
    19321 gaacagcctt ctgttgtttt gttttcatag cttatccaac taatattgtg tatgataaag
    19381 taggtgagaa aaatgacgga taaacaaaag atagatgaat ttttttggaa taaaacgacg
    19441 ccagaagtgg cacgggattt attggggatg tatttggagc atgacacacc agaaggaaga
    19501 ttagctggat atattgtaga cgcggaagca tacctaggtc cagaagacga ggccgcccat
    19561 agctatggtt taagaagaac accgcgtgtg cgggcaatgt atgaaaaacc aggtacgatc
    19621 tacctttaca cgatgcatac tcatcggatt ttgaacatca ttactcagcc agaagggatt
    19681 cctcaaggag taatgatacg tgcaatcgaa cccgccgcaa tgattgatca aatgagtaaa
    19741 aatcgtggcg gaaaaactgg tccagatatc agcaacggtc cgggaaaatt agtggaagca
    19801 ttagcaattc ctcaagaact ttatggtcag tctatagcag atagttcgtt acgcttagtt
    19861 tttgagaaaa aaaagacacc aaaaaagatc aatgctttgc ctagaatcgg tatcccaaac
    19921 aaaggtgtat ggacagaaaa gccgttgcgt tttgttgtgt cgggaaatcc ttatatctct
    19981 ttacaaagaa aaaaccaaat cgagaaagat tggggttgga ggaaagaaaa tgaaaaagaa
    20041 ggatctatta acatatttag atgaaataat tgaaaaacaa gtgacagact atgatgtagc
    20101 tttagattgg gatacaaaaa atcatacgat cgagatcgtt gttcgcttgt ttgcagaaaa
    20161 taaagcacaa tttgagattg atgatgcaga agggatcgtt tcgcaagaac caattatcga
    20221 atttgaagac ggcgtacttc tttttaatcc tcagaaatct gtttttgatg aacgcaatta
    20281 tctagcagta atcccttatg aaggaaaaaa agggttggca aaatcagtag ctgattcttt
    20341 agtggaatat ctaaatgaag tattagctca agggcaaagc gatttgcttg attttttgga
    20401 tgaagacgat gacgaagctg tattcgagct tcactgggat aatcagcaac tagcagaatt
    20461 agtagaagta aaacagcaaa atgaagcaga tacttattta ccgtacccaa gttattaagg
    20521 agtgacagat atgaaatgga atgaagtaaa agtagaaact gaaagtgaag cagtcgaagc
    20581 agttgctaat attttgatgg aggcaggggc gagtggtgtc gcgattgaag attctttaga
    20641 tgttgaacat tttcagtcgg atcaatatgg tgagatttta gataaaaatg attttacatc
    20701 gctgaaagaa ggcgcactag tcatggctta ttttccggaa acgactttct taccggaaat
    20761 cttgcctttt atcaaagatc gtatcacaca attacctgag tttggtctag ctattggaaa
    20821 aaataaagta acagttagtg aagtagagga aagcaactgg gcaacagcct ggaagaaata
    20881 ctatcatccg gtgcgtatta cgcgaatgct gacggttgcg ccaagctggg aaaactacca
    20941 gacagaagat cctctagaaa aaattatcac actagatcct ggtatggcat ttggcacagg
    21001 cactcatccc acgacttcct tgacattgac agcactagaa acagtcttgc gtggtggtga
    21061 aacattgcta gatgtgggaa ctgggtcggg cgtgctaagt attgcagcaa aatatcttgg
    21121 tgcaaaagat gtctatgcct ttgatttaga cgaagtagcc gttcgttcgg cgaaagaaaa
    21181 tatggatatg aatgaaatag ccaaagatgt ccatgtatca gctaacgatc ttttgacagg
    21241 aatcgagatt gaaagtgatg taatcgttgc gaacatttta gcagatatca tcttattgat
    21301 gatcccagat gcttggcgtt tactgaagca aacaggcacg ctgatcgttt caggaatcat
    21361 tgaagagaag aagcaaatgg ttctggatgc catgttagaa caagggttta tcgtggatca
    21421 aattttccag caaaaagact ggtatgcaat tattttgaaa aaaccagagg tggaatagat
    21481 gcagcggtat tttttaaaag aatcatatga atcaaaagac tattttgttt tagaagggga
    21541 aaactatcac cacattgtac gggttatgag gatggaaccc gaggatgaag tttttttggc
    21601 attcaatgat caaatagcca ttgttgcaga aatcacggag attactgaag aggctgttta
    21661 tctgaaagaa attaaaaaag aagaaaatca aaaggaactg ccaagttcga ttaccatagc
    21721 gagtggctat cctaaagggg aaaagctgga ttggatcgtt cagaaatcca ctgaattagg
    21781 agcgcaagct tttcttggtt tcccggcatc agcctctgtc gttaaatggg atgcaaaaaa
    21841 acgtatgaaa cgacaacaac ggcttgaaaa gattgctcaa gaggcagcgg aacaatccca
    21901 tcggcagatc gtgccatcag tagagttatt ggaaacgaaa caagatttat ttgagcggct
    21961 agatgattat gacgtggtct tggttgctta tgaggaatca gcaaagcaag gcgaaaaatc
    22021 aaatgcagcc aaaattctta gtgaaacaaa accagatagt cgaatcttag ctgtctttgg
    22081 accagaaggt ggattatccc gcgatgaagt cgattatttt gtagaacaca aagggatact
    22141 ttgtggatta ggaccaagaa tccttcgtac agaaacagca cctctttatt tattaagtgc
    22201 tgctagctat caatgggaat taatgaatcc ttctttcagc taacgttctt cattaataaa
    22261 agagtatcga cagaaagaat tgaaaaaata gtcaacaatt tgtataatag aaacaattat
    22321 ttatacaatg gatacgaaaa atcgtttgaa aaagctttta aaaagcgaac atttccgtaa
    22381 aaaaacgtat aactgcacgg attttgggac aattatcaaa cagatatttg tcccgattcc
    22441 cgttttaccg aaaaaagaaa gggggatcga ttcctgtgac aaaagaagaa attttaacgg
    22501 gacccggtgt cataaagctc gttagtcaat acatgggtcc cgaacatgta gcatttgttg
    22561 agaaagcatg cgaatacgcg actgctgcac atgacggaca gtttagaaaa tcaggcgaac
    22621 cctacattat tcatcctatc caagtcgcag gtatattagc agatttaaaa atggatcccc
    22681 atacagtggc tacaggcttc ttacatgatg ttgttgaaga tacagaaatc actttagaag
    22741 atctgagaga agaatttggc gatgacgttg ctatgttagt ggacggcgta accaaattag
    22801 ggaaaataaa atataaatcc cacgaagagc agctagcaga aaaccaccga aagatgctgc
    22861 tagcaatggc tcaagattta cgagttatca tggtcaaatt agctgataga ctacataaca
    22921 tgcgtacgtt gaagcacctg cgagaagata agcaaagaag gatcgctcag gaaactttag
    22981 aaatctatgc gcctcttgca catcgtctag ggatcagccg gatcaaatgg gaattagaag
    23041 atacagcact tcgttatcta aatccaaaac agtattaccg tatcgtccac ttgatgcaga
    23101 cgaagagaga agaacgtgaa aaatacgtaa gtggtactgt tgaagatatt cgaatagcga
    23161 cagaagagct ggggattttt gcagaaatct atggacggcc aaaacacatt tattcaatct
    23221 atcgtaaaat gaaagatcag aaaaagcagt tcaacgaaat ttatgacttg ctagctattc
    23281 gagtgatcgt agattcaatc aaggattgtt atgctgtatt aggagcaatc cacacaaaat
    23341 ggaaaccaat gcccggcaga tttaaggatt atattgccat gccaaaagct aatatgtacc
    23401 aatctttgca tactaccgtg atcggtccgg caggaaatcc ggtagaaatt caaatccgaa
    23461 cacaggaaat gcatgaaatc gctgaattcg gggttgctgc acactgggcc tataaagaag
    23521 gaaaaaatga aaaagtagaa ccagatggta tgacgaaaca attaagctgg ttccatgaga
    23581 tactcgaact tcaagacgaa agctatgatg cttctgaatt tatggaaggc gtaaaaggag
    23641 atatctttag tgataaagtc tacgtcttca caccaaaagg agacgttact gagttaccaa
    23701 aaggatccgg accattggac tttgcataca gtatccatac agatatcggt aacaaaacca
    23761 ctggtgcaaa agtaaatggc aaaatggtgc agcttgatta caaattgaaa aacggagata
    23821 tcattgagat catgacttct ccaaattcat ttggcccaag tcgcgactgg ttgaaattag
    23881 ttgctactag caaagcaaga aataagatca aacgtttctt caaagcccaa gatcgagaag
    23941 aaaatgtgat caaaggccac gaatccgtgg tcaaatgtat tacagatcta ggatttacgc
    24001 ctaaagatat tttgacgaag aacaaactgc aagaagcact cgatcgtttt aattatcaaa
    24061 cagaagatga tctctatgca gctgtagggt atggagaagt tagccccttg acgatggcca
    24121 atcgtctgac tgaaaaagaa cgtaaagaac aaaaaatcga gcagcaaaag caagaagcag
    24181 aagaaatcat gaatcagccg aaaaaagaac ctgacaaaat gaaagtacgt catgaaggtg
    24241 gcgttgtcat tcaaggggta gaaaacttac taattcgtat cagtcgctgc tgtaatccga
    24301 ttcctggtga tgatatcgtt ggttatatca ctaaaggcag agggatatcc attcatcgtc
    24361 gagattgtcc gaatgttcag cctgacaaac caaatgtagc agaacgtttg attgaagtcg
    24421 aatgggaaga tacatcgaat acacgaaaag agtatgatgc agatttggaa atttacggct
    24481 ataatcgttc aggcttattg aatgatgtac ttcaaacagt caatgcgcta acgaaaaatc
    24541 tcaacagcgt tgaagcacgg acgaataaag ataaaatggc gacgatccat ttgacggttg
    24601 gtatccagaa tttatcccac ctaaagagta tcgtggataa aatcaaagca gtacctgatg
    24661 tctacagtgt acgccggacg aatggatagg aggacagata tgagagcagt tgttcaacgg
    24721 gtaagtaaag ctgctgtgtc agtcgatcag caagaaattg gaaaaattgg ctacggccta
    24781 cttgttttat taggcattca tgaaaccgat acgcaaaaag atgtggacta tctggtaaaa
    24841 aaaattgcac aaatgcgtat ttttgaagat gaacaaggaa aaatgaatat tagtgtagaa
    24901 gatgtgggag gacaaatttt aagtatctct caattcacac tgtttgcgga tacgaaaaaa
    24961 ggaaatcgac caagctttgt ggaagccgca cgaccagaaa cagctattcc tttatacgaa
    25021 tcattcaatg aaggaatcag aagtcgcggc atcacagtcg ctaccggaca attcggagca
    25081 gatatgtcgg tttctctcgt caatgatgga cctgtaacga tcattattga ttctaaaaac
    25141 aaataaagta atctggtttt cactagtaaa aactatgaaa cacgtcgctt aagttagact
    25201 gataaactct aacttaagtg gcttttttgt ctgcaaaaag cgcttctttt gtcagcagtc
    25261 ggaaaaaaag ttaagcttaa attatacaag ttatttttta taggaggttg ctgaagatga
    25321 aagaagtacc agtagtagat atcaaaatca cagatttaaa aaaattgtat caaaaaggat
    25381 acaacatgtt ggaggagtta cgccatgaag cggacgctcc cgtcgtcaaa gcaaagattt
    25441 tcaataaaga agctatcacg atctacggat catcagcagc aaaagtattt tatgatccaa
    25501 ggaatttcaa acgaaaaggt gctatgccaa aattagtatt gaagacactt tttggtcaag
    25561 gtggagtaca gactttggat ggagctgctc atcaccatcg gaaaaatatt tttatggatc
    25621 taatgacacc ggaaagaatg gaagattatc atcgtatctt agataagaat ctgacacaag
    25681 cacttgaagc acagcatggt caatttgaac tatttgattt aagtaagatg gttttcttta
    25741 catctatttg cgagtgggca ggtatcaatt tatcagcgat ttctaaagat gaggtcgaaa
    25801 aattagcaga atatcaaatc tctatgatca gcggaacgtt tacttctccg attgatcaca
    25861 taaaaggtgt cgaaaatcgc aaaaaatcag aaaaatgggc gcaaggcttg attgaagaag
    25921 ctcgacaaaa tcctgtggct ggaaaagaaa atgtggcatt atatgctttt gccaatgcca
    25981 cagatttaga tggtcagctt ttacctctgg aagtggcagc tgttgaatta ttgaacatca
    26041 tccgtccaac ggttgctcta actgtgtggg cggcattgat gggacatgca cttttcagta
    26101 gaccagattt gtatcagcaa ttaaaaaatg acttttcgac gttacaagat ccgtttattc
    26161 aagaaatgag acgctattat cctttcttcc caatgctacc tgcgatttcg ctgaaagaag
    26221 tagaagtaga tggttatcgt ataccagaag gcagttgggt tattttagat ttatatggaa
    26281 cagaccatga tgaacgaaca gttgaagcgc cagattcctt tatgatcaaa cggtatgtag
    26341 ggaaagcaaa agatatttcc tataaagaag aatatgagat gattgcacaa ggcgggggaa
    26401 attttcgaca aatgcatcgc tgtgcaggag aatggatcac tcttcatagt ctacgtgtgt
    26461 tttccgatca gctagtaaat aagtttgagt tctctgtacc tgaacaagat tggacgattc
    26521 cattcaatca gtttccgact tatccgaata gccgagcgct actttacaag aattagatta
    26581 gcataaactt atcgaaaaaa aggaagatca aacagtgctg atcttccttt tttcatatta
    26641 ctataaattg ataaggtcaa ttgatcaaaa tccacgaaat gcttcatcaa tggtttgata
    26701 atcttcattg gataaatgca aatctaaagc ttggacattg tcagatactt gctctggacg
    26761 cttagctcca ggtataacta cagacactcg tggattcttc atgtaccaag ctaaaacaag
    26821 ttgcgcagga gtggcttggt atcttttagc aatggggcga agtacatcga cagcggttaa
    26881 aatttctctg aaacgttctc cttggaaatc tggatttctt tttcgaggat ctccttcacc
    26941 aaattgtttt tcctcaccaa gttcatattt tcctgtcagc aaaccggaag caagaggaaa
    27001 atagggaaca aaactgattt tgtttttttc aagataaggg aataattctt tttcagcctg
    27061 ccgatggatc aaactgtatt tatcttctac tacatcgaca tatccatctg cattcgcttc
    27121 tttcaattgt tctaacgtga agtttgacac accgactgct cggatttttc ctgcttcttt
    27181 taattcgtgc aatgtagcaa ctgattcatt ttttggtgtg ctttcatccg gaaagtggat
    27241 ataaaaaatg tcgatgtaat cagtttgcag acgttttagt gcatcttcca ccgattgttt
    27301 gagaaactca ggagaattat caaatgttcg ccctttattt ggtacatgag cagcttttgt
    27361 agcgatgacg acacgtgagc gatcatattc tttttccttc agtacctcgc caatcagttc
    27421 ttcggaacgg ccgtttccgt aagcataagc ggtatcgatc aaattgatcc cgctattcaa
    27481 agctgtacga actacttgtt ttcctgtctc atcttccaaa ccgtcaaaaa gattatgtcc
    27541 tccaacggca tttgctccta atccaagctg ttctgcgtag acttgtgaat gtccgattct
    27601 tatttctgcc atagctgatt cctccttttt gtctagtcta aaacaaaata ccaaaaagct
    27661 gaactaaaac gtttttgtga ggggaaatag tcagatatct cttgactttg agactggttt
    27721 ttagtaggtt ataagtaata tcgaatgtca atgaaagagc gagtaagttt ttgaaacttt
    27781 acaagagagg atcatcgagg ctgaaaatga tctaaagttt cattagccta aagacactct
    27841 ggagatggac gagtgaaaag ccgtcccgcg tacgagcgtt attcgtaaga ggaaagagaa
    27901 atctttcaaa attaggtggt accgtgtatg aatttcattc acccttgttc atgatgaaca
    27961 agggtgattt ttttatttac atagctaaga aagggagaga aaactatgag tttccaaaga
    28021 ccaaaaggaa caaatgatat tttgccaggc gaatcagaaa aatggcagtt tgtcgaagaa
    28081 acagcacgtt tattattcag agattatcag tataatgaaa tgcgtacacc gatttttgaa
    28141 cactatgaag tgatatcccg aagtgtaggg gatacaacgg atatcgtttc aaaagagatg
    28201 tatgattttt atgacaaagg ggaacgccat gtgacgcttc gaccagaagg tacagcacca
    28261 atcgttcgtt cttttgttga gcataaattg ttcggcccag agtatgcgaa accgttcaaa
    28321 actttttata tgggaccaat gtttcgctac gaacgccctc aaaaaggacg gttacgtcaa
    28381 ttccatcaaa tcggagtaga agcatttgga tcagaaaacc ctgcaactga tgtggagagc
    28441 atggtgatgg cacttgattt cttcaaacag ttggggatca cgcaaatccg gctagtcatc
    28501 aattcattag gtgataaaga aacgcgtcaa gcctatcgtc aagcattgat cgactatctt
    28561 ttaccttttg aatcagagct gagtgaagac tctaaacgcc gccttcatga aaatccatta
    28621 cgcgtattgg acagtaaaga caaacgagat caaaaatttg tggcagaagc tccatctatc
    28681 ttagattatc taagcgagcc tgctcaaaaa cattttgata ccgttgtttc catgctggat
    28741 gcattggctg ttccttatga aatcgacagt aatatggttc gcggactaga ttattacaca
    28801 catacgattt ttgaaatcat gagtgacgca ccaaaaatgg gggcacaagc aacgatttgc
    28861 gcaggcggac gttatgacaa tctagtggaa gaactaggtg gtccttcaac acctggcttc
    28921 ggatttgcaa tgggtatcga gcgattactc ttgactatgg aggcagagga agtagttatc
    28981 cctgcattta atgagttgga tgcttacgtg gtcgcactcg gagacgaaac aaatatcgaa
    29041 gcattgaaag tggtccaagc gattcgaaac tttggttttt cagctgaccg cgacttcatg
    29101 aaccgtaaag caaaagcgca atttaagaca gcagataaag cgaatgccaa attagtattg
    29161 gtgatcggtg aagatgagct tgctagtcaa acgattaatg tcaaagcaat ggcaagccga
    29221 aaagaaaaaa gttttccatt agaagagata tatgaacatt ttgatgaagt ctatgatgaa
    29281 atgactttat tcgagtagga ggaaaaaaat aaatggcaca aagaacgatc tattgcggat
    29341 tagtttccga acaacaatta gaacaaacag ttacattaaa aggatgggta caaaaaagac
    29401 gagaccttgg gggagtaatc tttatcgacc tacgtgatcg tgaaggaatc gttcaaatcg
    29461 tctttaatcc tgaaatcaac aaagaagcat gggaaatcgc ggataaatgt cgcagtgaat
    29521 acgtgatcga agtgactggg gaagttagaa gacgcggaga aaatgcagta aatcctaaaa
    29581 tggccactgg tgaattcgaa gtgattgcaa gtgaaatcgt gattttgaat caagcaaaaa
    29641 ccccgccatt tcaaattgaa gatgatcaag caatcagtga cgaaatacgt ttgaaatatc
    29701 gttatttgga tctgcgtcgt ccaaaaatga ctaaaaacat caaattaaga aatgcgacaa
    29761 caaaagcgat tcgtcattat ttagatgata atgactttct cgatatcgaa acaccttacc
    29821 tagggaaatc tacaccagaa ggcgcaagag actacctagt tccttcacgt gtccatgctg
    29881 gacatttcta tgcgttgccg caatctcctc aattgtttaa acaattgctg atgaatgctg
    29941 gattcgaccg ttattatcaa atcgttcgtt gtttccgcga tgaagattta cgtggagacc
    30001 gtcagcctga atttacgcaa gtagatattg aaacaacgtt cttaacagca gaagaaatcc
    30061 aaacttacac agagggattg attgcgaagg taatgaaaga agttcgcggt atcgaagtca
    30121 cattgccatt tcctcgtatg acctatgatg aagcaatggc tcgctacggc agcgacaaac
    30181 cggatacacg ttttgatatg gaattgatcg atctaagcga tacagtcaaa gaagtagaat
    30241 tcaaagtctt ccaaatggct cttgaaaacg gcggtgtcgt gaaagcattg aatgctaaag
    30301 gcgctgcaga tcgctactca cgaaaagaca tggatcagtt aggtcaatat gtaggacaat
    30361 tcggagctaa ggggcttgca tggctgaaag tagaagaaga cggattgaaa ggtccaattg
    30421 ctaaattcat gggagaagca acagaagcaa tcattaaagc aacagatgca aaaccaggtg
    30481 acttgctgat gtttggcgca gataaaagtg aaatcgtcgc tgctgcatta ggtgctatcc
    30541 ggacacgttt aggaaaagaa ttaggactaa ttgatgaatc gaaattcaat ttcttatggg
    30601 taactgattg gccacaattt gaattttcag aagaagaagg tcgatatgtc tctgctcacc
    30661 atccattcac gatgccaaaa gaagaagata tcccgttatt ggctgaagac cctgcaaaag
    30721 tctatgcaga agcttatgat atcgtcttga acggttatga actaggcgga ggttctatcc
    30781 gtattcatac tcgtgagctt caagaaaaag tactagaaac tctaggcttt acaaaagaac
    30841 aaatggaaga acaatttggt ttcttgttaa cagctttaga ttacggattc cctccacatg
    30901 gcggtattgc attaggattg gaccgttttg caatgttatt agccggagaa gataatattc
    30961 gtgaagtcat tgcctttcct aaaaacggaa aagcagcaga tgtgatgagt gatgcaccaa
    31021 gtatggtttc gcctttacaa ttgttcgaat tgaatattga tgtaacgaat atagaagaat
    31081 agccgataaa aaggtaaaaa ggatttgtcg aatacgcttc ttttgacaac cttgatttaa
    31141 ttgaaaaaca ctttataatg aagccataac atataaagcg gggcttttcc atgaaaaaaa
    31201 cattcgaaaa ttgggcttat catgattaca cgaccaagct ttcggtatct atcgtttatg
    31261 cgttgatcgc atcagtcgca ttgaatttct tttatcagcc aggacatatt tattcaagtg
    31321 gtattactgg tctagctcag attttgacga ctttgtcaaa atcactgata ggattcgaag
    31381 taccggtatc aacaactttg tatttactga atataccttt gtttgtattg gcgtggttaa
    31441 aaatcgggaa gaagtttaca attttcactt ttatcacagt cactttgacc tccctttgta
    31501 tccatatttt accggaaaca gtcctatcta ccgatccaat catctgtgcg ttgtttgggg
    31561 gggctgtgat gggactaggt attgggctag cgttgagaaa cggcctatca tcgggcggtc
    31621 tagatatcgt gagtatcacg attcgtaaaa aaacaggaaa gtcgattggt tctatttcga
    31681 tctacttcaa tgcattgatc gtttttgttg ccggaattct atttggctgg caatatatgt
    31741 tttacagtac gttgtctatt ttcgtcagtg gaaaagtaac tgatgtcgtt tatactaaac
    31801 aaaagaagat gcaggtaatg atcgtaacga aacatccaga aaaagtagta aatgaaatcc
    31861 aaaactgtat gcgtagaggg atcacgatca tcaatgaagc agaaggtgct tataagcatg
    31921 ataagcagac agtattgatg acgatcgtta cacgatacga actgcctcta cttagagaag
    31981 caatgaaagc ttctgatcca caagcttttg taagtattgc agaaaacgtc cagatacttg
    32041 gtcgtttcta tgaggatggc atttagatcg agtttgacaa aaattcatga aatactgctg
    32101 tagacagacg ttcgtttgtc tgcagttttt ttctaccata gtagaatcag caaagaaaaa
    32161 ctgctttttt atttgaaatt ttcttaaagt tgaaaaaaag catgtttatt tttttaaatt
    32221 tatgggatga tagaaaaaaa tagtagagaa aggacacgat tctacttgct attttcactt
    32281 aatacccgta tattacgaat gaaaaaagtt tatgaaaagt tggaatattg aatggaaaaa
    32341 caaaaaaggt taaaaaacag ccgctacatc actgggtttg atgggctccg ttcattagct
    32401 gtggtgggtg ttatcttcta tcaccttctg ccaactagta tgaaaggcgg ctatttgggc
    32461 gttccgattt ttttcgtcgt atctggttat ttgatcacgg atctgctgcg gcaggaatgg
    32521 gaacaaaatg gaaaaatcaa tatttggcaa ttttatgtca gaagaatgaa gagactctat
    32581 ccggcacttg tttttatgct tgtgacagct tcggcttata tcactttgtt tcagcgaggg
    32641 ctgttaaaca atcttcgagg agttgtggtc agcagcttac tgtatgtcaa caactggtgg
    32701 caaatcaata acggtttatc ttatttcgat cgatttgcta atgagtcacc gtttacgcat
    32761 atctggtctt tagcagtaga aggtcaaaac tatttggttt ggccgatctt gtttgtattg
    32821 ttgatggtat ttgttcgtaa aagaaaatgg atcttttata ctgtgttagg tacatccttc
    32881 ctctccgcca tcttgatgat gatcttgtat acaccaggag gcgatccaac ccgtgtttat
    32941 tacggtaccg acactcgtct gttttctata tggttgggaa gtgcgcttgc gtttgtttgg
    33001 ccaagtacgc gtttaaagaa aaacatcccg aaacaagcga aaaatattct gaatatcgct
    33061 ggaggaatct cgcttttggc actgattctt tgcttcttct ttttagatga tcattacaat
    33121 ttcatctatt acggaggaat gctcctagtg agtctgttat gcgtagtgct agttgcagtg
    33181 acagcacacc ccggagcaag tttgaatcga tggctgacaa atccagtatt tacttggatt
    33241 ggcaaacgaa gctatggcat ttatctgtat cagtttccag ttatgatttt ttatgaagca
    33301 aaggtgactg atattgccga tcatgttttg ttgcatactt tagtggaaat cacattgatt
    33361 ctaatcatca gtgaactttc ttatcgatat gtggagcgtc cgctagcacg ttttgattat
    33421 ggtcgtacat tccaagtgat gaaaggatgg ttcagcaaac cgatcatcag taagagcaaa
    33481 ccatgggttg ttccaggcac attacttgta gcaattgcac tcgttggttt cgttacggca
    33541 ccgaaaaacg ctgtaacagc cgatcaaaaa caactgcagg caaaaatcgc tgaaagtaaa
    33601 aaattagcag aagaaaccag aaacaattca gaaaacacca ctagttcggt tgaccaagcg
    33661 atccttgata agtacgagtt gtccaaggca caagggaata aggcacaaaa attagaacta
    33721 acggcatttg gtgattcagt tatgttggat gctgcaacgg atctacaaga actttatcca
    33781 aaagtagtgg tagatggaga tgtcggacga caattatatg ccagtgtacc gtacattgaa
    33841 aaattaaagg aacaagattt gttgaaagac actgttctga tcggactagg aacgaatggc
    33901 tcattctcgg aagctcagtt tgatagtgtg atggatgcaa tcggtgatcg aaaagtatac
    33961 tgggtcaatg tccgagtacc gacgaagcgc tggcaaaatg acgtgaatgc gatgcttgaa
    34021 cagatgacga aaaaatacga caatatgacg ctgattgatt ggtacagcta cagtaatgac
    34081 catagtgact ggttttatga tgatcaagtc catccaaatc ctgaagggat gacacattac
    34141 attcacttag tcagcgaagc cttgctagga ggaagttcaa gtacgaacag cagtgagaca
    34201 aacgtgacag aatgatagct acaaaaaact tcaggcaaaa acatttgttt ttgcctgaag
    34261 tttttttata tttaccgtgt ttttaacatt catatagatt caggaagcaa aacggttgag
    34321 tgtgtctgta aataacgttc tttttgtttt cgggtgagtt ttttgaatgc agcttctgct
    34381 tttgttgctt cgcttcttga agaaaatact tctgcatgga tcatcttaac aggtcttctt
    34441 ttttgaagac gagtatattt agcaccagta ccattgttat gttcctctaa tcgtctagaa
    34501 agatcggttg tatatccacc ataaaatgtc tgatctttac agaataatac gtaaaaataa
    34561 tgttcatttg ccatagagca tctcacgaat ctctgcagtg tattctccat ccatattgta
    34621 agtgatcaat ggtggagcga ctttgaatcc gtctaatttg ccttctttga ttccttcaac
    34681 taacaaaata tttgcctctt ttccaggttt tgggtaaaca aattggatcc ttttaggtgc
    34741 aattcgatag tcttccatga cctgaatgat ttctaagaac cgatcaggac gatggaccat
    34801 agtaaagcgt ccatttgttt ttagtagctt acttgaaata tcgatcactt cttctaacgt
    34861 cgtatgaatc tcatgacggg cgattgccag gtgtttatta gggttcgttt tatttgttgg
    34921 cagccctttg aaataaggtg gattacagac gactaagtca caagaattat gtcgaacgac
    34981 agataagctg tctttcagat cgatggtgtg gacagtcatt tgttcattta aatggttaag
    35041 cgcgatacta cgtcttgcca tgtctgctag acgaggttga agttcgatag cgtcgatagc
    35101 cgcctgggtt cgtttactta aaaaaagtcc aactgcgcca tttcctgcac aaaggtcaac
    35161 aatcttccct tttttaggta cacgggaaaa gtgagcaagc agcacagcat ctaaagaaaa
    35221 agaaaacact ttggaacttt ggataatctt gatatcttct gcgtataatt ggtcgattcg
    35281 ttcgtcttcg tgaagcatgg attccctcca aaatgaaaaa aatagtcgtc tgtattatac
    35341 tatttttatt aaaaagaacc aaggtggctt gtcaaacctc tattttttat gcatactatg
    35401 accataagaa gggaaaggaa gagactatgt tttatcgatt tatgcgcggg gtagttcgag
    35461 tactattagc cttagttaat ggaaatgccc gctatgagaa taaagaagtt ttaccgcaag
    35521 atgagaatta catactagtt gctccccatc gtacttggtg ggacccatta tatctggcgg
    35581 tagctgcagc acccaaggaa ttcagcttta tggcaaaaga agaactgttc aaaaatccag
    35641 ttctgcgatt tatattaact cgatccaatg cttttccagt taaaagagaa aatccaggac
    35701 caagcgtcat taaaacacct gtaaagattt tgaaatcgac aaatttgagt ttgatcatgt
    35761 ttcccagtgg gacaagacat gctacagaac ttaaaggcgg aatggcattg atttccagaa
    35821 tgtctaaagc gaaaatcgtg ccagctgtat atcaaggtcc gttgacactt ggggatctgt
    35881 tcaagcgtca gagagtgaca gtgcgtttcg gcgaaccaat cgacttatca gatatcaaga
    35941 aaacggataa agaaggtatg gcggagatcg aacgacgaac acaagcagct tttgacaaat
    36001 tggacaaaga agtgaaccct gatttcaaat atgaagtcaa aaaaaaataa aatgataagt
    36061 ttatgcgtgg gcggtctttt gaatctactg tcctgttcag ttcagacttt ttcaatgaaa
    36121 acgagggaga gacgtcaagt ctgccctctt tttgcgttcc aatatgtaaa atagaagaca
    36181 ggtgtcatgt aatggatcaa agtgttataa taattagaag gacatttttt gaggtgattg
    36241 aatgcgtttt ttacatacag ccgattggca tatcggaaaa aaactacaag gttatgactt
    36301 gattgaagac cagcgtcatg tactatcttc tatactagat atcgcgaaag aagaaaaagt
    36361 agaggcaatc gtgattgccg gagacttata tgataggagt gtcccagctg ttgatgccgt
    36421 agaattatac aatgaattga tggtcgattg gaatttaaag gaaaagatcc cgatttttgc
    36481 tatatcagga aatcacgata gcagtacgag actttcagcg ggtacgccat ggttcagtta
    36541 ttcgaactat tttttgcgaa cacagctagc agaagcattt gaaccagtcg agtttaaaaa
    36601 cgtacaattt ttctttcttc cttactttga accaattgca gcgagattat attttgaaga
    36661 tgacaatatc cgaacgatca agcaagcggt agccaaggtg atagataaaa tgcaggagct
    36721 atttgattca gaaaaaaaac aagtattgat tagccatttt tttgtaatgg gaagtgtaaa
    36781 atctgattcg gaaacgaaaa tcgaagtagg cgggttggat tcgatccctg gtgaactact
    36841 tacaccgttt gattatgtag cactaggaca tttgcataat caagctgctt tgagacagga
    36901 taatgctcgc tatagcggtt ccccattgaa attctcttta tctgagatca accaaaaaaa
    36961 aggcgtatgg atcgttgacc tgacaacagg cctggagttg aattttaggg agatcgaacc
    37021 cctgcatgat attgaagaaa taacagcgag tttcaaagaa ttgctggatc ctgcctttta
    37081 tcagtccgtc aatcgggaga attacatcta tatctatctc actgatagaa cgatcatccc
    37141 gaatatgatg aaccagcttc ggcaaatata tcctcgtatt ttggggattg aacgggcaaa
    37201 cggtcgagca gaacaaacaa agcgcaaacg aaaagtacta gaaatgaaag atcctcaaaa
    37261 attagcagaa gcatttttta gtgaaatgac ggaagagcag ctaactgcaa accaagaaaa
    37321 atggctcgga gaaacgttgc aagaaatcat ggaaatggaa tgatcaagaa tgaaaccgaa
    37381 aaaattacaa cttaaaaatt ttggtccttt tatcaatgag accgtagatt tttcacgttt
    37441 gacagaagca ccgctttttt tgatcagcgg gaagacagga gctggcaaaa cgacgatttt
    37501 tgatgggatc accttcgcac tttttggtga aacttccgga agacttcgct ctggaaaaga
    37561 gatgcgttct ttgtttgcta caccagacga agaaacaagc gtgacttttt cttttgaaca
    37621 tcagcagatg agctatgaaa tcgaacgaaa accagaacaa gttttagcaa aacgaaaagg
    37681 aaacggaaca aaaaaacagg cagccaaagt aacgttgacc atttttgatg ggaaaggaaa
    37741 agaaataaaa caaatcacaa aacgtacaga agcagatcag ttgatcagag aactgatgaa
    37801 tctcgatgcg aaacagtttt ctcaaatcgt tttactaccc caaggagaat tccgtaattt
    37861 tttggtttca tcaagcagtg ataaagagac tgttttacgt catttattcg gtactcaatt
    37921 tttccaacag ttcaatgagc gattaaaaga aaaagcaaaa caacagcaac aaaaattgga
    37981 tcatttagag caagagctgc atcttctgca aaaaaggttt gttttagtca aagaagagga
    38041 accagcagca gggtttgaag ccgttttagc ccaatggaca aaccatcagg caatactcga
    38101 aaaacaaatc acggaagaaa aagaagctct aacggaactt caggaaaaac aaaagcaact
    38161 agaaaattcc tactatcgtt ttgaaagctt gaaaaaaagt tatgaagaaa aaacgatatt
    38221 aataaacaag caaaaggaat tagctgctca aaaagacgaa atagaggaaa agaaacgatg
    38281 gattgggtat tatgaattta cgcaacgatt agtcgaacca atccagcgcc tacaagaaat
    38341 aaaagttgaa aaaatagaac tgtcacaaaa aagtagtgag caaacaaaga aactagcgat
    38401 gactacgcag aattatgaag agtggcaaaa aaatgaagca aaccgcgtac gccgacaaac
    38461 aaaaatcaaa gaagctgctc aaaaactgca aaacaaacag atgatggtgc caattgtcga
    38521 atccttacgt agtaaaaaac aagacgcaga acaattaaca atttcattgg ataaagaaga
    38581 attgaatgcc gagaagctgt atcaaaatct cgctatctat caggaaagaa ctcgaattct
    38641 tcaagaaaat ttactggatc aggaaaaact gcaagaagat cgtcttgctt ttggacagtt
    38701 aaaatatcta gatgaaaagc agcaagaaat agaaaaacaa aaagcaaaag acactgggtc
    38761 gctcgcacag ataagagaag aactcaaaaa agcaactgaa gaaataacaa aaaatagtca
    38821 gctattgaaa gaacagacag aacaagcaga acagctgaaa agccaatggg caaagcagca
    38881 aattgctcgt cttcagcttt ttttgcgtcc aggggagcca tgtcttgttt gtggatcaac
    38941 ggaacacccc atacaacaat taaaacacga acagccaaat aaggaagata tcttaaaagt
    39001 agaacaacaa ctggcagaag ctgagtctgc tgtagaaaga actcagcaaa tcattgccaa
    39061 aagtgaagca catgaaaata atcttcaaca acaattatca gatttagaac aaaaaatcat
    39121 ggcaacgaat atacaattgg ctgaacaaga agaacacttg caacaggctt tgaaaaaggc
    39181 atttcctgag ataacagaac aaaaaacaaa aacaactctt gtagtaatcg aacaatcttt
    39241 agatagacga aaaagcaaga tggccaatgc aagaatagag ctggaagaaa taagacaaca
    39301 agcagaaaag ctcgaacaac aattagctgt ctacaaacag cagcagacag aaaaaaataa
    39361 tcagctccag caactgcaag gagaaatcaa aagtttagaa caacaattgc aagatacgga
    39421 tagtaactgt ttagaagagg agatacgacg acttgaaaaa cagttagaag aagactcgaa
    39481 tcaactagct gttgagcaga aagcaggagt gcaattgttg caagatcttc atacgcttcg
    39541 gacacagctt gatcttcaac atgaacaaat agaaaaaata gatgaaaaaa tagaaaagga
    39601 acaagaaaga atagctaaaa agttagaaag ccagtcgtat ttttcaacaa ttgaagaaat
    39661 ctgtgcattt gcacaacagc aagcacaata taaagaaaac caacgtacag ttacttctta
    39721 tcatgaagag caattagtga cagctgaccg gctgcgtcaa ttagaaaata tccagctaac
    39781 tgagacattc ccagatacag aagagatcag ccaacagtta gaagaaataa gacgtatgat
    39841 cgaaataaag caagaaaaga tatacggttt acaagaacaa aaaattagta atcaaaaaat
    39901 ctacgatgaa tgtctttcga tttatcacac aagccagacg aaattagatg agcttacgca
    39961 attacagcag ctttcgcaaa cattcaacgg agaaaatcct aagaagacta gtttggaacg
    40021 gtatgtgctt caggtttatc ttcaagaagt gttacaagta gcaaatgatc atctccaacg
    40081 tttaacgaaa aatcgttatc aatttgagct agcggatacc attggcagtt atcgagggaa
    40141 aaccggatta gaaatcaata tctatgatga tcaggcaggt atgtctcgaa gtgcgcatac
    40201 cctgtctggc ggtgagagtt ttattgcagc actttcttta gcattagctc ttgccgatgt
    40261 gatccagaca caagctggtg gtgtagcaat cgatgcattg tttattgatg aaggatttgg
    40321 gtcattagat gaagaagctt tggaaatggc aatggaagct ttagaaacga tcgaaagtga
    40381 aggaagaatg atcggcatca ttagtcatgt aagagaattg aaagaacgag tattacaaca
    40441 aataagaatt gatacagaag gtagcggaca aagcaaaata cgctatcaac ttggataaaa
    40501 agggagattg gtaactatga aatggagtat tccagaaaaa gtcattgcac gtggacgtca
    40561 atacttgcaa gaaggccgag tgttatcggt tgtccctgac caagaagaaa acgtgtggca
    40621 tgcagaagtc ttgggcagtg aattgtatat ggttgatttg gatggtacag caaaagagat
    40681 agattactgc caatgtccct attgggagga acataaatat tgtaagcata cagttgctgt
    40741 ggaactttat ttacggtcga aaaatctatc tcgtatcatg aaaaaagacc agccaatgct
    40801 agaaccggta aaagcaacaa gtgagggaga aatcattgca aaaggttttt ctcgtctaaa
    40861 aacacaaaac aatcctcaag cggtgcaacc tttgattatt gaataccaag tagaaacgat
    40921 tgagactaat cagtatcacc cagagctttc tattttggca ctttacttgc gtatcggttc
    40981 attggcatca ccgaaaaaaa catatatcgt aaaaaacatc tatgattttt tacaagctta
    41041 cacagaaaaa gaaacttaca ctgttaataa acagtaccag tttcgtctag ataaacgggc
    41101 gtttcaaaaa gaagatcaaa aaatactcac gcatcttgca ggaagtgctc agacgcatca
    41161 attattaggt acgaacggct tacaagtcaa aggaaaacta gataaaagat atctgcttct
    41221 cccagtagaa caagcccgct tcctgttaga gcagatgaat cagactacac gtttgcatct
    41281 gcagataaat gaacaaaacg atcaaggaat acaattttcc gatcaaaaca aacctttatc
    41341 attcaaagtg gaaaaatttg gagaagatta tttgctgcaa gcattgaatg attttgattt
    41401 tttctttatg cattatcagt ggggagttat ccaagggaca ttttattctc tgacgaaata
    41461 tcaacaaacg gtttatcaaa cttggaaaca attgattcgc cgattggaga aaccagaagt
    41521 agtgttcaag aaaaaagaat taccgtcttt gtttaaagag attatccctc tgctgtcaga
    41581 gatcggcgac gtagctattg cccctgcagt agaagaggaa gtagcagata tccccgtcga
    41641 atttattttc tttttccgaa aagcaaaagg aaaaatccaa gctcgagtcg atttcgtcta
    41701 tggcgaagtc atctattcga ctgacccgaa gcatgaggtc tcgacagaac aggcttttca
    41761 ggtgttacgt gacacagtag aagagaaacg agtacttgat ctattcagaa tgtatcgcta
    41821 ccagaaaaat gaaactggtt atgaacgtcc attgccaagc ggggaagaac tatatgcctt
    41881 tttccgcaca gaactatctg tcttccgtca gtttggtgaa gtcagacttg gaagaaaatt
    41941 gcgagagttg tatttagatg cgcataaaca tcaaccgaaa atcgaagtaa ccgagaccgg
    42001 ttcatggctc gatattcgat tcgatgtgac agggatagag gagcaagaaa tcgatcatgt
    42061 cctgcaaagc ttgctgagaa atgatgcttt ttatacatta gaaaatggtc aggttctttc
    42121 ttttgattca gaagaatttc aacaaacaag ccaagtgttg caacaattac gggaatcgat
    42181 acgtacagaa gaaggaacga tccatgtacc taaaaatcaa ggattgatca ttcaaaatca
    42241 attggaaaaa agcaatgcta cttttagtga atcgttccaa acgatggtac aagatctcat
    42301 tcatccagaa agataccagg cacagcttcc caaaggattg aatgcaacga tgagagatta
    42361 tcaaaagcaa ggttttcgat ggttgaagat gttaggtcat tatcagtttg gcggtatttt
    42421 agccgatgaa atgggacttg ggaaaacact acagacaatt gcctttttac tttcggaaaa
    42481 agaagaacgg aaaagcttct ctgctttgat cgtagcgcct gcgagcttaa tttacaactg
    42541 gcaggcagag gtgagaaaat tcgccccttc tttaagtatc caagtaatca atgggaataa
    42601 aaaagaacgt gaagaattac tggctaaaga cacagatatc cgagtgactt cttatgccag
    42661 cttaagacag gatctagcta attatcagtc gcaaaaaatt gattatttga ttcttgatga
    42721 ggcacaaatg gtcaaaaata gcagtacgaa aactgcacaa gcattgagag aattagctgt
    42781 acctcagcgg tttgcactga gtgggacacc aatcgagaat aatttagaag aattgtggtc
    42841 attgtttgca acgattatgc caggattttt cccgactaaa acaaaattca gggaacttgc
    42901 cgcagaagaa attgcgcaaa tgattcgacc gtttatttta cggcgagata aacaaactgt
    42961 gttgaaagac ttgccggaaa aaacagagat gaatctatat tctgcactta cagaagaaca
    43021 aaaaactgtt tatttagctt acttgcgtca aatgcgtgaa gaaatcacat caatggattc
    43081 tgaagcattc aagaaaaacc ggatcgggat acttgctggt ctgacaagac tgcgacaaat
    43141 ttgctgcgat cctcgtctgt ttattgaaga ttaccaaggc ggttccggca agctcgaaca
    43201 agtaaaagat ctactggtag ctgccaaaga gaacaaacga agagttttgc tgttttctca
    43261 atttacaggg atgctgacta tcttgcaaga agagttagcc gagctaggga tctcgacatt
    43321 ttatttaaga ggcagtacga aaccacaaga tcggttaagt atggtagacg catttaatgc
    43381 tggcgaaaaa gatgtttttc tgatttcctt aaaggctggg ggaactggat tgaatctcac
    43441 gggagcagat acggtcatct tgtatgacct ttggtggaat cctgccattg aagaacaagc
    43501 tgctggacgt gcacatcgga tcggacaaaa aaatgtggta gaagtgtggc gtatgatctc
    43561 tgaaggaacg attgaggaac gcatggattc actccagcaa gaaaaacgcg aactgttcca
    43621 aaaagtgatc caaggtaatg aagaacagtt gacgaaactg actgaagaag acatccgcat
    43681 gattttaagt gtaggagaaa tcgaggagta agagactcga aaaagcgttc agtaatgggt
    43741 aagaaagcct ttctaaagaa gcgattgttt atttgattta aaaaatagca aggaggctgg
    43801 gattccattt tatcccagct tccttgctat cattttttta tttctatttt taaaggttat
    43861 acaaagattg tcttcattgt ctctaacagc tgatcaaaag aagaaatctc gatatcgcaa
    43921 attggagtct gttcaatttt gcgttctcga tggttgaacc aaagcgcttg ccagttagca
    43981 ctttttgcac ctagaacatc attgtcgtaa ttatcgccaa cgtataaggt ctcttctgga
    44041 agcatatgaa attctttctc agctagctga aaaatctctt tttctggttt ttggaaacct
    44101 gttgcttgag aaatgagcat attgcgggaa ggaatccaat tgttcaattg aagttgcttc
    44161 agtttttttg tctgatggtc agtcggccca tttgtgataa ttcctaatgg gacattcttt
    44221 tccttcaaga aatcgagggt ttttttgacc tcctcatgca agcagatatt atcaagttct
    44281 tcctcgtaaa ttttttgaaa taagaggcca tcttcttccg taatatgagg gtagtctaaa
    44341 tcttttagtg attggctgat ccgatgtgct cgcatatatt ctagtgtcca atctcctgcc
    44401 attacttttg ggaagttttc atcactatga tggcggaacc ggatatatag tggatgcata
    44461 tctgcatctg aaacaagcgg aacgactctt ttgaccgcgt ttcgaaatgg ctgctgctga
    44521 tcatacatcg tatcatcaac atcaaacaca actgatttaa tcaaaatttt acacgccttt
    44581 cggttttcat tgattttttc acaaatcctt gactattgta acagaaaaaa ttgtctaaaa
    44641 aagctgataa ataaaggttt ttcttactat atttctattt ccttgacaga ataaggtttt
    44701 tatatttcag tttttttcac taaaaatcgt gaaacacgtc aataagtttg atgaacaaat
    44761 taatcattat ggtagaagtc gattgattta ttttaatgca atctctgtgg aattttcgaa
    44821 agatttatt
//
LOCUS       DAFLWC010000012        42434 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.012, whole genome shotgun sequence.
ACCESSION   DAFLWC010000012 DAFLWC010000000
VERSION     DAFLWC010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42434
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.012"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            28..474
                     /locus_tag="L1V17_000639"
     CDS             28..474
                     /locus_tag="L1V17_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1235425.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(533..994)
                     /gene="mscL"
                     /locus_tag="L1V17_000640"
     CDS             complement(533..994)
                     /gene="mscL"
                     /locus_tag="L1V17_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HBN1235426.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            1246..2514
                     /locus_tag="L1V17_000641"
     CDS             1246..2514
                     /locus_tag="L1V17_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBN1235427.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            2507..3793
                     /locus_tag="L1V17_000642"
     CDS             2507..3793
                     /locus_tag="L1V17_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBN1235428.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            4532..5455
                     /locus_tag="L1V17_000643"
     CDS             4532..5455
                     /locus_tag="L1V17_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1235429.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            5664..6242
                     /gene="pgsA"
                     /locus_tag="L1V17_000644"
     CDS             5664..6242
                     /gene="pgsA"
                     /locus_tag="L1V17_000644"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBN1235430.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            6482..7723
                     /locus_tag="L1V17_000645"
     CDS             6482..7723
                     /locus_tag="L1V17_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBN1235431.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            7832..8881
                     /gene="recA"
                     /locus_tag="L1V17_000646"
     CDS             7832..8881
                     /gene="recA"
                     /locus_tag="L1V17_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBN1235432.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            9292..10848
                     /gene="rny"
                     /locus_tag="L1V17_000647"
     CDS             9292..10848
                     /gene="rny"
                     /locus_tag="L1V17_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBN1235433.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(10927..11733)
                     /gene="proC"
                     /locus_tag="L1V17_000648"
     CDS             complement(10927..11733)
                     /gene="proC"
                     /locus_tag="L1V17_000648"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBN1235434.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            11874..14447
                     /gene="mprF"
                     /locus_tag="L1V17_000649"
     CDS             11874..14447
                     /gene="mprF"
                     /locus_tag="L1V17_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBN1235435.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            14589..15452
                     /locus_tag="L1V17_000650"
     CDS             14589..15452
                     /locus_tag="L1V17_000650"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBN1235436.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            15697..16635
                     /locus_tag="L1V17_000651"
     CDS             15697..16635
                     /locus_tag="L1V17_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HBN1235437.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            16658..17338
                     /locus_tag="L1V17_000652"
     CDS             16658..17338
                     /locus_tag="L1V17_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBN1235438.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            17311..18135
                     /locus_tag="L1V17_000653"
     CDS             17311..18135
                     /locus_tag="L1V17_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBN1235439.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            18302..19120
                     /gene="purR"
                     /locus_tag="L1V17_000654"
     CDS             18302..19120
                     /gene="purR"
                     /locus_tag="L1V17_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBN1235440.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            19623..20996
                     /gene="glmU"
                     /locus_tag="L1V17_000655"
     CDS             19623..20996
                     /gene="glmU"
                     /locus_tag="L1V17_000655"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBN1235441.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            21090..22061
                     /locus_tag="L1V17_000656"
     CDS             21090..22061
                     /locus_tag="L1V17_000656"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBN1235442.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     regulatory      22067..22169
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            22235..22804
                     /gene="thiT"
                     /locus_tag="L1V17_000657"
     CDS             22235..22804
                     /gene="thiT"
                     /locus_tag="L1V17_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HBN1235443.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     gene            complement(22885..23658)
                     /locus_tag="L1V17_000658"
     CDS             complement(22885..23658)
                     /locus_tag="L1V17_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235444.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            23925..25625
                     /locus_tag="L1V17_000659"
     CDS             23925..25625
                     /locus_tag="L1V17_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBN1235445.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            25595..25813
                     /locus_tag="L1V17_000660"
     CDS             25595..25813
                     /locus_tag="L1V17_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HBN1235446.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            25833..26723
                     /locus_tag="L1V17_000661"
     CDS             25833..26723
                     /locus_tag="L1V17_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBN1235447.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            26741..27025
                     /locus_tag="L1V17_000662"
     CDS             26741..27025
                     /locus_tag="L1V17_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235448.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            27512..28126
                     /gene="gmk"
                     /locus_tag="L1V17_000663"
     CDS             27512..28126
                     /gene="gmk"
                     /locus_tag="L1V17_000663"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBN1235449.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            28131..28436
                     /locus_tag="L1V17_000664"
     CDS             28131..28436
                     /locus_tag="L1V17_000664"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBN1235450.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            28689..31097
                     /gene="priA"
                     /locus_tag="L1V17_000665"
     CDS             28689..31097
                     /gene="priA"
                     /locus_tag="L1V17_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBN1235451.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            31112..31603
                     /gene="def"
                     /locus_tag="L1V17_000666"
     CDS             31112..31603
                     /gene="def"
                     /locus_tag="L1V17_000666"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBN1235452.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            31596..32534
                     /locus_tag="L1V17_000667"
     CDS             31596..32534
                     /locus_tag="L1V17_000667"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBN1235453.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            32534..33892
                     /gene="rsmB"
                     /locus_tag="L1V17_000668"
     CDS             32534..33892
                     /gene="rsmB"
                     /locus_tag="L1V17_000668"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBN1235454.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            33905..34645
                     /locus_tag="L1V17_000669"
     CDS             33905..34645
                     /locus_tag="L1V17_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBN1235455.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            34642..36711
                     /gene="pknB"
                     /locus_tag="L1V17_000670"
     CDS             34642..36711
                     /gene="pknB"
                     /locus_tag="L1V17_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBN1235456.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            36876..37775
                     /gene="rsgA"
                     /locus_tag="L1V17_000671"
     CDS             36876..37775
                     /gene="rsgA"
                     /locus_tag="L1V17_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBN1235457.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            37788..38438
                     /locus_tag="L1V17_000672"
     CDS             37788..38438
                     /locus_tag="L1V17_000672"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBN1235458.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            38439..39077
                     /locus_tag="L1V17_000673"
     CDS             38439..39077
                     /locus_tag="L1V17_000673"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBN1235459.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            39232..40086
                     /gene="mreC"
                     /locus_tag="L1V17_000674"
     CDS             39232..40086
                     /gene="mreC"
                     /locus_tag="L1V17_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBN1235460.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            40090..40599
                     /gene="mreD"
                     /locus_tag="L1V17_000675"
     CDS             40090..40599
                     /gene="mreD"
                     /locus_tag="L1V17_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBN1235461.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            40854..42428
                     /locus_tag="L1V17_000676"
     CDS             40854..42428
                     /locus_tag="L1V17_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBN1235462.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
BASE COUNT        14002 a         7577 c         9176 g        11679 t
ORIGIN      
        1 aataaaaaag cagggggcgt ttgcttagtg gaatatcagg taaagaaatt tgaagaattg
       61 tcaacagcag agttttacgc gatcgtcaaa gaacgaatcg cagtttttgt tgtggaacaa
      121 cagtgtcctt atcaagaagt tgatgacatt gatggagaag cttggcatac gttttttcaa
      181 gatactgatg ggaagatcct tgcctacacg cgagtatatg aagaagcgga gagtatccat
      241 tttggacgtg tccttgttca tcaggacaac cgtaaagatg gtttaggaag aaagattgtt
      301 caagaaacga ttaacatgat ccagaaaaat tttccagaaa aaccaatcgt gatcggcgca
      361 caagaatacc tacaagcttt ttatgagtcg tttggattca aggcaatctc agatgtgtat
      421 ttggaagatg atattccaca tatcgacatg aaaaaggaac aagtagcaag ttaagaatct
      481 aaaaaaagaa agccgacact gaaaatcggc tttctttttt ttagattctt tattatttag
      541 aagtatcgga aagatttgtt tgctctactg gatgtgtatt gtcttctgcc acttgtttgg
      601 caagaagatc gcgtatgtca ctaagataat cttctgcagt aggagtttct tccacttcca
      661 cttgctcttc tttggagcgt aaattcttcg cacggtttgc cgctttgaca actaagaata
      721 agacaaaacc agtgatcaga aatgtaatga tagcactaat aacgttacca aacgcaaatg
      781 tgacgccttt tgtcggcgac cagtcaagaa ttgaaagtgc tccttctaaa tcagaagtac
      841 ctgtgatcat tgcgacaaac caacctatta gtggtgtgat caagccttgc accacttggt
      901 ttacgatgct tgtaaacgca ctaccaataa caacgccgac agcaagatcc aagacatctc
      961 cacgcatgat gaactctttg aattctttga tcatgaatga ccctcccttc ttttatttgt
     1021 ctttagtata tcgaaaaata aaaaataaaa aaacaatata cgcttttagc cgtctgtttc
     1081 ttttgataaa aaacatctat gctatactat aaagtgtaac atcatttaga aaaaacggcg
     1141 aattgcctga acttataaat ttcaagcaga ggaataagta aaaaaggcag gttgacccat
     1201 taaaagagta agcgggcaat caactgtgaa aaggagcata taaatatggt gtatcaattg
     1261 gcagaaggcg tgaatcttca tgtcttacca acaaaacaat acaaaacgat ccggattttt
     1321 atccgtttta ctgcgcgtct gcaacaagaa gtcatcacga aacgttcact tctcagcagc
     1381 atgttggaaa caaatagttt gaattattcg gatcagacaa agttaagtgc gcaacttgca
     1441 gagctttatg gcgcaagctt tggattatca gttagaaaaa aaggaaattt acattggcta
     1501 aacgcaggga tcagttttgt gaatggtgaa tatgtcaatg atccaaacct tttttctcaa
     1561 gcggtagatt ttttaaaaga ggttttattt tatccaaata ttaaaaatca tcagtttgat
     1621 cagttgacgt ttgacttgga aaagaacaat ctgcgtctat atttggaaag tttgaaggaa
     1681 gataaacaaa cttttgcttc ctatgccttg caagaacttt attttgaaaa cagcccggaa
     1741 caaaagatcc cagggttggg cgtagtcgaa gatttggaca agatcactgc tagttcgcta
     1801 gcgtcctact atcaagaaat gatggcaaat gatcaaatcg acatttttgt tgtcggcgat
     1861 gttgatccgg acaaagcagc tgaagcagtt gggcaattac catttgagtc gcgggaaaca
     1921 gtttatccag atctgtttta tacccaacct caagtgaata tcgtgaagga acgacaagta
     1981 cgtgagccaa tcgttcaagc aaagctgaac ctagcttatc agacaaatgt gtattacgat
     2041 gaaccagaac gttttgcgct aatggtcttt aacggtttat ttggcggttt tcctcactct
     2101 aaacttttca tgaatgtcag agagaaagaa agtctagctt attatgcctc tagtagcgtg
     2161 gatacgttcc gaggattcat gagtgtccaa accggtatcg atgaaaagaa ccgaaatcaa
     2221 gtacttcatc tgattcacga gcaattagaa agtttgcgaa atggtgaaat aacagagttg
     2281 gaactgtctc agacaaaagc aatgctgaga aaccaatatc tgctttctct agactctccg
     2341 caagcggcaa tcgaagcttc ttttttggac agctggctgc cggaaacaaa attatctgat
     2401 gaagaatggt tgaaacgtat ggagagcgta acgatcaaag agatacaaca agtagctgag
     2461 caaatcgaat tgcaggcaat cttcttttta gcaggaggaa atgcaaatga ataaaacaga
     2521 atatgagcaa atcaatgaaa cactttatca tgaagtactg ccaaacggtt tgaccgtgta
     2581 tttgttgcct aaaaatgact atcacaagac atatggtttg ttcagtacga attatggttc
     2641 gatcgataac gaatttattc cctatggtga aaaagaaaag gtgaaagttc cagatggaat
     2701 tgcccatttt ttagaacata agttgtttga aaaagaagat ggtgatgtct ttcaattatt
     2761 tgggaaacaa ggagcttccg ccaatgcttt cacaagtttt acgaaaacca gctatctgtt
     2821 ttctacgacg gatcaggtag aaaagaatct gacgactctg atcgattttg tacaagcacc
     2881 ttacttcaca gaagaaactg taaacaagga aaaaggaatc atcggtcagg aaatccaaat
     2941 gtatgaagac gaccctaact ggcggatgtt ttttggcata ctaaataact tgtatcctac
     3001 acacccattg catatcgata ttgcgggcac ggttgaaagt atcgacaaaa tcacagctca
     3061 agacttgtat acgtgctatc ggacgtttta tcagccaagc aatatggttt tatttgtagt
     3121 tggtaagatg gagcctgaga aattgatgaa acttattcgg gaaaaccaag aagcaaaaaa
     3181 tttccctcca aagcaagaaa ttgtacgtta tttccctgaa aacacaaaag aaatcatcaa
     3241 acaaagtgca ttggaagcag ccattacacg agataaattt gtacttggta ttaaaggatt
     3301 agacacattg ccgcaagaag gaacagaact gttacgctat aaaacagcaa tcaatctgtt
     3361 gttccaaatg attttaggca atacttctcg aaactatcta gcgatgtaca atcaaggaat
     3421 tatcgatgac agctttggtt ttgaattcag cttggatcgt gaatttcact ttgcggactt
     3481 cagcggagat acggacgaac cagagaaagc agcagaaaaa gtcaaagaaa tcattcttgg
     3541 attcgctgat gatccggaag tgtcagaaac aaatctcgat ttgctgaaga agaaaatgct
     3601 tggacaatat ttccaatcat taaattcgat cgaatatatt gccaatcaat ttacgcaaag
     3661 tttatttggc gatcgaactt tatttgatct tcctgaaatc atcgattcga tccaaatgaa
     3721 agacgtactg gcagctgggg aagcatttat aagtgaagag gccttcagcg agttttacat
     3781 gagaccaaaa taaaccagta ttttatgagg aaaagtctta aatttcgttt tagacttgta
     3841 gtaggaacct cctccaaaat cagcttttat ggtattctta gttgtgttgg aaaaattagt
     3901 gagaaaataa aacaaatcat gctctctttt aatcaactta tattaaaata aaatcaaacg
     3961 aagtaatcaa agaggttgtg acagaagtgg tcagcttcaa gaaataagaa ggaatttacg
     4021 aaaattgctt ctcaaatttt tgtgatattt cggcttattg ccgaagaagc tacttctgga
     4081 acaccgtgta ccaagaggtt gtgaaaaagc tgccctgcat caagtaataa gaacagccaa
     4141 gtaaaaacag cttcttaatg tttttaactt ggttggactt attaccgcag atgcaagctt
     4201 ttgaacaccg tttaaggaag aggttgtgaa atcagcgttt tgacctgagt attagagaaa
     4261 catacggaaa aatatctcct tatattttgc cggtttttga gctaataccg aggaacagct
     4321 gattgaacac cgtttaagaa agaggtcgtg agcctgccgt ttaactccga gtcacaagga
     4381 acaagttcaa aaaacagctt cttatattta ttggatattg tgacttgtga ccgaggagtt
     4441 ggcaggagaa caatgtttat tcggaaaaaa ggagctgtga catgactttt gtcacagcac
     4501 ccaaacataa cgtctttcgt tgcaacagca gatgcttcgg agaatcaaac agactggaga
     4561 agatgaacga gtggcttttg aaaccatcgg agaaaaatta cggcaagcac gcctgaataa
     4621 aaaaatatct ttagatgaat tacagcagat tacaaaaatt caaaaacgtt atttggaagc
     4681 aatcgacaat gatgattttg accaattgcc tggtaaattt tacgtgcggg catttattcg
     4741 gcaatacgct gaagctgtag gagaagatgg agaccattta gtcgatgttt ttgatgggaa
     4801 aagcaaattg acaggatcgg tccctgaacg tccgcagcct gaaacagtaa gtacttctag
     4861 aaaagcaatg catcaggaag aatcgcatcc aagtcgcttt tggacaagtc ttcctgtcat
     4921 tttattagga ttggttgctt tggcgattgt cgttgtcgtg ggctatatga cttggcaaga
     4981 tcgtcaagct gatccaataa tcggagacac agcttcttcg cttaaagtag aaggatcagt
     5041 cgaggagtcc tcttcctcag agcaaagcac gcagaccaaa gagtcttcta cagtagaatc
     5101 aacaacaaaa tcaagtgaag aaaagaaaat ggcaatagct acaggagaag attctggcag
     5161 tgccatcgca gtaaatatca cagacgctac caagcctgta acccttgaat ttactgctgt
     5221 caatcgtgta tggttaggtg tgctagtaga caatgcctat gtttatcaag ggacactggc
     5281 agcaaatgaa acacagagta ccgtgttacc ggaaacagca acaaatgcga ccatcacgat
     5341 tggtgcagca agcaatgcaa cgatcaaagc gaatggagaa tccgtaccag ttaatccagg
     5401 ggaaaacaat cagagtccaa aaaatgtgaa ccttactctt caatacgcag aatgatcgta
     5461 taaattagtt tacgcatctg tttacttgta ggtataaaaa agaaggatcg tgacaaatct
     5521 gtgtcgcggt ccttcttcgt taattcaaaa agatcaattt caataaaaat actcctttga
     5581 ataaattcat ttggaaaagt aaataatatc ggtggaaact tcgctgatag tcacgtagaa
     5641 tagggaagaa aggagtcgat agtgtgaatt taccaaataa attaactgta cttagaattt
     5701 gtatgatccc gattttcatt ttggttgtag gtttaccttt agattgggga caatttaacg
     5761 taggagacac cacactggct gtcacacagc tagtaggtgc agttattttt gctttagcta
     5821 gtatcacaga ctggttagat ggaaaaattg cccgtgcgcg aggccttgtc actaattttg
     5881 gcaagtttgc ggacccgttg gcagataaaa tgctagttat gactgctttt atcatgttgg
     5941 ttgaccaagg aaaggcccct ggttgggtag tagcgatcat tgtctgtcgt gaattagccg
     6001 tcacaggctt gcgtttacta cttgtcgaac atggagaagt catggctgca gcttggccgg
     6061 gaaaagtcaa gacggctaca caaatggttg ctattatctt gctgtttatc aataatatcc
     6121 cattcagcct gatcggtatt ccagtagatc aaatcatgct ttatgcttgt ctgatcttta
     6181 ctatctattc aggtgtggat tacttcatca aaaacagcgg tgtgttcaaa ggatcaatgt
     6241 aagtatcgtt tagtggagag gttgtgagcc tgccgtctaa ctctgagtca caagggataa
     6301 tttcaaaaaa cagcttttca tgttttatgt atattgtgac ttatgaccga ggttttggca
     6361 ggagaacact gtttatttgg aacaaggagc tgtgacaaga tttttgtcac agctccttgc
     6421 cctcttttta aataaaaaaa tataaaaata cagcgtatac tatataaggg agcgggaagt
     6481 aatgaaagca gaaataatag ctgtcggaac agaactttta ctaggacaag tcgtgaatac
     6541 gaatgccact ttcttgtcag aacagctagc tgatctaggt atcgaagttt attatcaaac
     6601 agttgtagga gataatcagc agcgtttaga agagttgatt gctctagctg aaacaagaag
     6661 tgaactcata ctcttatgtg gcggattagg accgacagaa gatgacctga caaaagaagc
     6721 aactgcggct cacctcggta agtctctcat acaaaatacg gaaggataca aaaaattatt
     6781 ggcatatttt gaaacaaccc atcgaaaaat gaccaaaaac aatctgcaac agtcccagat
     6841 tatcgaaggc ggggttcctc taccaaatcg tacagggctt gctttaggga ctttttatca
     6901 aacagataca catgcgtata tccttcttcc cggtccgcct aatgagttga aaccaatgtt
     6961 tgtggaacaa gtacgtcctt tactagagga acgttttcct tctgaagaaa aactaatttc
     7021 taaagttttg cgcttttatg ggattggtga atcgcgactg gtcactgagc taaaagatct
     7081 gattgagaca cagatcaatc caacgatcgc accatatgcc aaaccaaatg aagtgacatt
     7141 acgactgaca gtgaaaacaa atgatgttca ggcagggaat caagctcttt tagcattaga
     7201 agaaaaaatc caagaacgag taggggaata tttttatgga tacggcgatg ataattcgct
     7261 agcaaaagtc gtagtggaac tactgaaaga aaacaagcag actgtaacag cagcggaaag
     7321 tttgacagcc ggcgccttcc aagccgcatt aggcgacatt gctggtgtat ctgaagtatt
     7381 tccaggcgga ttcgttacct actcgctcca aacaaaagct ggttttctgg agattgatcc
     7441 ggagctatta gcagaatatg gaacagtcag caaagaatgt gtggagcaga tggccattca
     7501 agcacgtgag atagcaagaa cagattacag tgtagctttc accggagtgg ctggaccgga
     7561 cacgttagaa ggtcaatctg caggaacagt atggatcgct atttcatcta aagacggcgt
     7621 ggtttcggaa aaatatcact ttgccagaga tcgtgctgct atcagatata atgcggttat
     7681 gcaaggattt gatcttttga gaaaacagct tttaagaaaa tgataaatgc gaatatttgt
     7741 tcggtttttt cttgcttttt ttcactaaaa aagatatgat aaggataatg aaatgttgct
     7801 ctgatttgta aatataagga ggattatcgt attggcagat gatcgtaaag cagccttaga
     7861 tgctgcactg aaaaaaattg aaaagagcta tggtaaaggc tctattatga aattgggcga
     7921 aaaaatcgac caacaaatct ctacaattcc aagtggctct cttgcgttag atgtcgcttt
     7981 aggtgtcggc ggttaccccc gtggacgtat catcgaagta tatggacctg aaagttcagg
     8041 taaaacaaca gttgcactac acgctattgc agaagtacaa aaaaatggcg gaacggccgc
     8101 tttcattgat gctgagcatg cgttagatcc gcaatatgca caaaaattag gtgtgaatat
     8161 cgatgaacta cttctttcac agcctgacac aggagaacaa ggtctagaga tcgctgatgc
     8221 tttagtatca agtggggctg tagatatcgt agtagtcgat tcagttgctg ctttagttcc
     8281 acgagcagaa atcgacggcg aaatgggtga ctcacatgtc gggttacaag cacgtttgat
     8341 gtctcaagca ttgcgtaaac tctctggttc gatcaacaaa acaaaaacaa tcgctatttt
     8401 catcaaccaa atccgtgaaa aagtaggcgt gatgtttggg aatccagaaa tcactcctgg
     8461 aggacgcgca ttgaaattct acgcaacgat ccgtttggaa gtacgtcgtg cagaacaatt
     8521 gaaacaaggt acagatattg ttggtaaccg tacaaagatc aaagtcgtaa aaaacaaagt
     8581 agcacctcct ttcaaaatcg ctgaagtaga tgtcatgtat ggtttaggga tctcacaaga
     8641 aggagaactt ctagacatgg cagtagaaaa agacattgtt gataaaagcg gtgcttggta
     8701 ttcttataaa gaagatcgga ttggtcaagg acgggaaaac gctaaaatct atatggctaa
     8761 tcatcctgaa atgatggcag aagtttctgc tctagttaga gcagcttatg gtattggtga
     8821 agaagtcgct gtcccagaag atgaaaaagg acaagaagaa ttgcctttag tagaagaata
     8881 aaaattatga taaacaaaaa cggctggtct gaagagtagg tactctcctt gacctgccgt
     8941 ttttttattg aataaagaaa tcgtgagtta tttaattata cgagtgggta cataaaataa
     9001 aaatatctgt tcatctacaa agaataattt aatagaaaag tttctcaatt taaaggttta
     9061 cctatatgaa actagtgtca tttattttaa aaaccatcgt ttaatgaata agtagaaagc
     9121 cgtttctttg tttatttaaa gttgacacta cggggtacaa acattagaat aaagttgtgc
     9181 atgttttttg tacacatata tgcgaagatg catattgacg agtttagaat aatttatcat
     9241 agaagctgta tagatgataa aaatgaaaaa gatagtatgg aggtggattt tatggtattc
     9301 aacattctcc tcgctatcat cggtttaatt gtcggtcttg gtttagggtt tatggtcgca
     9361 aagtcacgtc acgagaaaga aatagctggt gcacaatcat cagctgctgg aatcatcgat
     9421 agtgcaaaaa aagaagcaga aactctaaaa aaagaagcat tgttagaagc taaggaagaa
     9481 aatcagaaat accgttctga agttgaaagt gagctgagag aaagtaagtt agaattaaaa
     9541 tctcaagaga atcgtttgat tcaacgcgaa caaacgctga atcgtaaaga tgactcgtta
     9601 gaaaaacgcg agaactcact tgaaagtaaa gaagaagcac ttagttcaaa acagcaatta
     9661 attgaagagc gagaaaaaga cgttgaaaaa atgattgaag atcaacaaaa agaactagaa
     9721 aaaattgctg gtttatcaaa agaggacgca cgagatgtca tcatgaaatc gactgaagaa
     9781 gagctgaatc atgagttaac tctaatggta aaagaatctg aacagcgtgc caaagaagaa
     9841 gcagatcgca aagcgaaaaa cttattatca ttagcgattc aacgctgcgc agcagatcaa
     9901 gtttcagaaa cgactgtttc agtcgttacc cttccgaatg atgaaatgaa aggtcgtatc
     9961 attggacgag aaggtcgtaa tattcgaacg cttgagacgc tgactggtat cgatttaatc
    10021 atcgatgata caccggaagc agttgttctt tccggattcg atccaatccg aagagaaatc
    10081 gcacggatga ccttggaaaa actgatacaa gatggacgaa tccatccagc gcgtatcgaa
    10141 gaaatggtcg agaaatctcg taaagaaatg gatgaacgta ttcgcgaata cggggaagag
    10201 gcagcgtttg aagtcggtgc tcatacactt catccagatc taatcaagat catcggacgt
    10261 ctgcgattca gaactagtta tggacaaaac gtcttgaagc attcggtcga ggttgcaaaa
    10321 ttagctggta tcttagcagc agagcttggc gaagatatcc aattagcaaa acgtgccggg
    10381 ttgctccatg atattgggaa agcacttgac catgagattg aaggatctca cgttgagatc
    10441 ggtgcggaat tagctgccaa gtacaaagaa aacccagtag taatcaacgc gatcgcttct
    10501 catcatggag atgtggaagc tacttctgtt atctctgtcc ttgtagctgc agcagatgcg
    10561 ctctcagcag caagacctgg tgcgcgaagt gaatcattag aaaactacat ccgtcgttta
    10621 agaagtctgg aaaatatttc gaacagcttc gccggtgtag aatcaagtta cgcagttcaa
    10681 gctggacgcg aagttcgggt aatggtcaag ccagaagaaa tctcggattt agacgctgtt
    10741 cgtttagtac gtgatattcg taaacgaatc gaagaagaac tggattatcc tggacacatc
    10801 aaagtaatcg ttattcggga aactcgtgca actgattatg ctaaataata aaaaatacaa
    10861 aagaagagcc gcggcaaaag ccacagctct tctttttttg taaggcacga aaaaacattg
    10921 ctatcattat tttttattca acatctcaag atctttctcg atcgtcgtat tgattccttt
    10981 gatgattgct gggatgaatc ctgcttcttc taaggcaact acacctgcaa cagttgtacc
    11041 gccaggagaa gaaacttggt ctacaagttc ccatggattt ttatcacttg aaaggaattt
    11101 ttgacaagaa cccataattg cttttgcagc aatctcagtg gctgtctgtt tggacaaacc
    11161 attcagtaca ccagtccgtc ccatcgcatc gatcagcatg taaacgaatg cgggtgagct
    11221 gccagcaagg ccaatgaatg tactgaaatc tgattctgct aaaggataga cgctgccgat
    11281 tgcttcaaaa atcatcgtag cttgctgaag ctgttcctcc gtggcagctt catttttgca
    11341 aatcgcagaa acgcctgctc ctacgctgac attgacattc ggcatcacac gtacgatgga
    11401 ggcctgagga tcttcaagcg ctgtttctaa atctattaat gattttcctg aagcaataga
    11461 aatgaataag actttctggc tatattctct tagttcttcc aatacttttt caatgatttt
    11521 tggtttcacg gctaaaagaa cgatatctga ttgtgatgca acttcctgat tacttttgca
    11581 tgcatggacg ccagtttcag cagcaaattt ttgtgcattt tcaaaatgtc cactggaaac
    11641 gaacacctct tctttcgaga ctgttccttt ttttaataaa ccatcaataa tagcttgtgc
    11701 catattccct gtgccgataa atcctacttt catgttatcc tctcctttag cattaggata
    11761 tctttctttt tctatcatcg caagcaaaga acaggtctaa agtggaaaaa ttaaaataaa
    11821 taagataaca ttggggtatg acacaaaagt atacaagtta ggaatgggaa aatgtgaaaa
    11881 ataaacgata cttgatgctg caatggataa aggaacatag tctgatttta aaactgattt
    11941 ttttcggctc cgtgttagtc tttgtggcaa atcaagtcgc aaatattgct aatggcatga
    12001 gttggcaaga tatttggcaa aggatgggac aacaaagccg catgacgatc ctgctcatga
    12061 ttctggctgg actgctgggt gtcactccga tgttgttgta tgattgggtg acgatcagag
    12121 tcttagaaaa acaaggaaaa ccaaaaatgg aaagaaaaga gtttcttctt gctgcgtggg
    12181 taacaaacac gatcaacaat ctcgccggtt ttggtggtgt ggtaggagca agtctgcggg
    12241 ctagttttta tggaaagcag acaaatagaa aaatggtttt agccactgta tcaaaagtcg
    12301 cactatttat gctgactggt ttgtctgtat ggtcgtttct tacatttatt gatgtctttt
    12361 ttattcagtc agaaagtatt tttcgaagct attggatctg gcttttcggc ggtagttttt
    12421 tagcaccagt cattttcttt tttgcttatc taaagagaaa gacattgttc ttcgagtttt
    12481 atccaaaagg cttgcttggt ctgctactgg catcctttgg acaatggacg ggagcccttg
    12541 cggtattttt gatcatcggc aagttgatga gaatagatat ttcgatgctt tcgatctatc
    12601 ctatgttcat gattgctaca ttgataggaa tgctgacgat ggtcccaggt ggaatgggga
    12661 cttttgacgt tttgatgatc ttaggaatga gtcaattgtc tgttcggcaa gatgtagcag
    12721 tagtttggct attatattat cggttgtttt attatgttct accttttatg acgggacttc
    12781 tattgttcat cacacataca ggagtcaaaa tcaatcgatt tttagataac attccgcgac
    12841 tgtttttcca aaaggttgcg catatcgtgc tcgtaagtgc tgtctatttt gcggggatca
    12901 tgatggtact tctatcaaca atcactaatc tgtctgcaat cagtcggcta tttcaagtat
    12961 tattgccgtt ctcattcaat tttttagatc agacagtgaa tctattggtt ggctttttat
    13021 tactcggcct tgctagagca ctttcagtaa aagtcaaaaa ggcatttctg cctacgattg
    13081 ctttactatc ttttggtatt ttaaatacaa tcacacgtac gttatcttgg cagttgatat
    13141 tggtatatgt cttgattctg ttagctgtgt ggttatccag aaaagaattt tatcgaacaa
    13201 aattcgttta ttcttgggga gctataatct ttgatgctag cttgttcggc tttttgttta
    13261 tcgtttacgc aattgcaggc tatcacagcg gacgcttttt agtcggtcga ataacaggaa
    13321 atcattttat tttgtttcct tcagatgatg tgtggttctc agggcttatt ggtttgggca
    13381 tctcattgct agctttagtg gcgctttatc aatatttagc tgaagatact acgaagcttg
    13441 gcagtgagta cgaaaaagac cgttttgacc gtttattgga aacatacgga ggcacagcta
    13501 caagccatca gcttcgcttg tcaggttaca gttattttta ttaccaagaa gacgaccaag
    13561 atcaagtcgt ttttggttat cagatcaaag gaaacaaatg ctttgtttta ggagatccag
    13621 ttggcaatcc taaaatgatg cgggcagcaa cgaatcagtt tatgaaacaa gcagattgtt
    13681 taggctatca gcttgcgttt tataagatat cagaaagcta cgtagtgatg cttcatgaat
    13741 tgggttttca cttcacgaaa gtaggtgaag cagggattgt tgatctagca acagaagact
    13801 tgtctcggct gagtcagcaa cttgaatatc aacgtttgat gaaagaagga taccatttta
    13861 cttggtacga tcaactgccg gaagaattac atcaagctgt aaatgaagtt tcacaaaaat
    13921 ggcttcaagg tgcacgagaa aaatacttct ctgtgggacg atttgataaa tcatatgtat
    13981 tatctagcgg tgtcggtatt gtccgtaaag atcaaaaagt cgttggcttc atcaccgctc
    14041 agccgatgac gaagaagcag gcgggatatg atttgttgcg ggtcttacct aaagaatctg
    14101 aggaattagc tgactatctg ttagccaatc tgtttattgt atacgagaaa atgggctact
    14161 cggaagccaa tctaggctta gctccattag ctaatgttgg agaaacagat ttttctttct
    14221 ttcaagaaaa agtcatgcat atcgtatata attatggtaa ttttttctat tccttccagt
    14281 ctgcttatga aaagaaatta aaatatgtcg atcattggga aggacgttat tttgcttata
    14341 ggaaaggaag taatttcgga tttgctacca tgcagctact cagtctgata ggaaaagaaa
    14401 aaggaaatgt tccgagtttg gcagaagaag tgctcacaga attataagaa tcactagaac
    14461 ttgtttggat tatgaagaga aaattctgtg aaagctgttg aaacgatgac aaaatcaacc
    14521 actaggcaga cataagctat acttttattt ttccctatga tagaatactt gcgacttaga
    14581 cttttcgaat gggtgagagg atggaattga ttgaaaaagc gccagccaag ataaatttag
    14641 gactggatgt attatataga cggcaagatg ggtatcatga gttggaaatg gtgatgtcga
    14701 gcgtagactt ggcagatcat ctattttttg aagaaataac agaagacaaa atcattgtag
    14761 aaacaaataa agcattttta ccggtagatg aacggaacaa tgtttatcaa gctgctttat
    14821 tgctaaaaaa taaatacaat atcaaaaccg gtgtcaagat ctttgttaag aagaatattc
    14881 cagtagcagc tggattaggc ggaggaagta cagactgtgc agctgctcta agagggatca
    14941 accaattatg gaatctgggc tgttcgttag aagaactggc agaaatcggt ttggaagtcg
    15001 gtacagatgt tccttactgt gtctacggaa gtacggcatt tgtcggtggc aaaggggaag
    15061 aaatccaagt attaccttct atgccacagt gctgggttgt gttggtcaaa ccaagaatga
    15121 gtgtctctac acgtacagtg tttagagaag tagatacgca agccatccaa catcaagaca
    15181 tccacggact tgctgaagcc atccgagagc aagattatca gcagatgatc aaaaaaatgg
    15241 gaaacagttt agaagatata acgggaaagc ggcatccagt catccatcaa atcaaagagc
    15301 gtatgatcaa gtacggagca gatgctgcat tgatgagtgg aagcggacca accgtttttg
    15361 ccttgtgtca acattattca agagcgcaga gagtatataa tgggttaaaa ggtttttgtg
    15421 aggaagttta tttagtacga accctgcaat aaaatataag aagtaaaata ggtgatgaaa
    15481 aactgaggaa tcctaaaatg gtattcttca gttttttatt gtagtgaaat ggctagatat
    15541 gagcagcaac tcatccattt tacgatttaa tcaagaatat acatgcttaa atcagaaatt
    15601 gatggatttc tattgactgt gtttttttat tttgatacat tagttcacgt taataaatcg
    15661 taaaattccg atttgttcat tgaaaggagc atataaatga aaaaatatct tttgacagct
    15721 acggtaatga taggtgcttt actgtttgca gcatgtggaa atacgaacaa ggaagcagac
    15781 aaaaaagagg atttgacgat cgttacgact ttttatccga tgtatgattt tacaaaagag
    15841 atcgtagggg atgaaggaaa cgtgaaactt ttgatccctg ctggaacgga gccgcatgat
    15901 ttcgaaccaa gtgcaaaaga aagagcagaa atttccgatg cagatgtttt cgtgtataat
    15961 agttcagaca tggaattttt tgtggattcg ttaaaggatt cagtggatag caaacagacc
    16021 ttgatgatcg aagcagctaa aggaatcgac cgtttagaat cgcaagaagc agacgaacat
    16081 gaagaatcag aagaagggca tggtcattca catgaatacg atccacatgt ttggctcgat
    16141 ccggtattag ctataaaaga agtcagaacg attgctgaag aattaggcga aaaatatcca
    16201 gataaaaagg aaacttttac gaagaatgcc gatgcttata tcaaaaagct tgaagcactg
    16261 gatcaaaaat actccgatga gctaaaagat gcaacaaacc gcacatttgt cactcagcat
    16321 gctgcttttg cttatttagc gaatcaatac gacttaaaac aagtagcgat ttcgggcgtt
    16381 tcaccagatc aggaacccac accaagtcgc ttagctgagc taaaagaatt tgtgaagaaa
    16441 aacaacatca aagtgattta ttttgaagaa aatgcctctt cgaaggtagc tgagacattg
    16501 tcgaatgaaa caggagtgaa gctagaagtg ttgaatcctt tagaaagctt gactaatgaa
    16561 caaatcaaag caggcgaaaa ttatatttct gtcatggaaa aaaatctgaa agctttaaaa
    16621 gaaagtatca attaagtttt agaatggagg ttgtaaggtg cgttatatcg aaatatctga
    16681 tttgaccttt tactatgatg atgaacctgt actagaagat gtctcttatc atgtagatgc
    16741 gggtgaattt gtcattttaa ctggagaaaa tggagcagcc aagtcaacct tggtgaaagc
    16801 atcgttagga ttactgaaac cttcaaaagg aatgataaag attgctgaga aaaatcaaga
    16861 aggaaaaaaa ttaagtatcg gttatattcc tcaacaagtt gcatctttca atgcaggttt
    16921 tcctagtacg gtgatcgaat tagtccgttc aggaagatat ccaagaggcc gctggttcaa
    16981 gcgtctctct gaaaaagatc atcaacatgt acagcgtgct ttagaagctg tagggatgtg
    17041 ggatatgcga aatcggcgaa taggtgaatt gtctggcgga caaaagcagc gaatcagttt
    17101 agcgcgtatt tttgctactg accctgactt atttgttctt gatgaaccaa caacaggtat
    17161 ggatgaagaa tccagaaatg aattttatcg tcttctccga catagtgcgc atgtccatgg
    17221 gaaatcagtt ctaatgatca cccatgatca tgaagatatc aaacagtatg cggacagaca
    17281 gatccgactg gtgagaaagg aggattctca atggcgttgc tttcatatga attcatgaga
    17341 agagcgtttc ttgccgctat cttcattgcc ggaatcgccc cgatgctagg tgtgttttta
    17401 gtgatcagaa gacaatcgct gatggctgat acgctttctc atgtctcttt agcaggggta
    17461 gcgttaggat tctttttgaa ccttaatcct acacttacga ccatgctagt cgttgtatta
    17521 gcagctgtga tattggagta tctgcgaacg atctaccgaa cctattcaga aatctccatt
    17581 gccattttaa tggctggtgg tttggcgcta gcgttagtat tgatgaattt gagcggaggg
    17641 aattcagcaa caagtatcca atcctatctg tttggttcga tcgtgaccat tacatgggag
    17701 caagtcatct ttttaggaat cttattcgtt gccatcggta tattgttctt tttattcaaa
    17761 cggccgatgt atgttctgac ttttgatgaa gataccgccc acgtggatgg gctacccgtt
    17821 catttgatgt cgatgatgtt caatgtgatt actggtgtgg ctattgctgt gatgatcccg
    17881 attgccggtg cacttttgat atccgcaatc atggttcttc ccgcagcaat cggtatgcga
    17941 ttaggcaaaa gcttcaatgt cgtgattgct atcagtgttt gtgtaggatt tctagggatg
    18001 ctgtcaggac taactagctc gttttatcta gatacacctc caggagcaac aatcacatta
    18061 gtctttattg ctttgttcct gattgtaaat atcatcaaac gaatattggt tgccttcaga
    18121 agaaaaaata actaaattat aaagaaaaga agccttataa aaacgaaaaa ttttttatag
    18181 gcttcttttt attttaataa ataccgaact attttcttat tttttcataa aatgctcgaa
    18241 tttttgaaga aaaacttata taatgtaaaa cgataaaatt tcttaaaagg agttggaata
    18301 ggtgaaagta cgtcgcagtg aacgtctagt tgacatgaca cagtatttat tgaatcaccc
    18361 gcatgaattg atttccttaa caagctttgc cgaacgttat gaatctgcta aatcttctat
    18421 cagtgaagat ttgggaatca tcaagaaaac atttaaagaa cgagggtatg gaaccttgga
    18481 aacaatcccg ggtgctgcag gtggtgtatt gttcatccct gaaatttcat atgaagaggc
    18541 gaaaaaatat attgaatctc tagcagaacg tctatcagaa caagaccgtc tgcttccagg
    18601 aggatatgtt tatctctctg atttgttagg agaacctgaa ctgctgcgtc aagttggaag
    18661 aatcattgct tctaaatacc ttggtgaaaa aatcgatgct gtaatgactg tagccacaaa
    18721 aggcgtacct attgcccaag ctgtgtccta ttatctgaat gcgccattcg ttattgtacg
    18781 ccgggactca aaaataacag aaggatcaac agtaagtgtc aactatgtgt ctggatcttc
    18841 tgaaagaatt gaaaagatgg aactgtctaa gagaagtttg aaacgtggtt cacgtgtcct
    18901 tgtagtggat gatttcatga aaggcggcgg aacagtcaac ggaatgaaga gcttgattga
    18961 agaattcgaa tcagaacttg ttggcatcac tgtatttgcc gaatcaaaat tcaacggtca
    19021 tcgcgccatc gatgattata cgtcactgct ttatgtcaaa gatgtagata ctcaaacgaa
    19081 aaatattacg gttgtgccag gaaattattt ttcagaataa gaggttgtga aaaagccgct
    19141 tagtttcgag tagtaagaaa aattttgtga aaatggcttt ccacattttt tcataaattt
    19201 ggcttaatac cgagaaactg gcttttgaac accgtttatc tagaggttgt gaaatcagcg
    19261 tcctgtcctg agtattagct caataaacgg aaaaattgct cctcatattt tgccgtttat
    19321 tgagctaata ccgaaggtca gctgattgaa aaacgtttaa tgaagaggtt gtaagcctac
    19381 cgtttaactc taagtcacaa gaaacgattt caaaaaacag cttttcatgt tttatgagta
    19441 gtgtgacttg tgaccgagga gttggcagga gagcaccggt taccaaatag ataggcccgt
    19501 tatggtctat ctattttttt atccagaaaa cgctgggata aaagaaaatc acttgttttg
    19561 ttgaaaaaat gggtatactg ggataaactg aaatcagcaa actatattta ggagtgacgc
    19621 agttggacgc acgttatgca attattttgg cggcagggaa aggtacccgc atgaagtcaa
    19681 aattatataa agttttacat cccgtttctg gtaaacctat ggtagaacat atcattaatc
    19741 gggtcagtga aacgaaacca gatgaagtga ttacgatcgt tggacacgga gcagaacaag
    19801 ttaaagcaca actaggagaa cgcagtaaat atgcgttaca agcagaacaa ttgggaacag
    19861 gacatgctgt tttgcaagct gcttctttct tggaaggaaa aaaaggaaca acgttagtta
    19921 tcagtggcga tacaccatta ttgactactg aaacgctgaa caatcttttt gaatatcacc
    19981 aaggaaaaaa tgcaagtgca acgatcttga cggcacaagc agaaaaccca acaggatatg
    20041 gacgaatcat ccgtgaccat attgggatcg tagaaaaaat cgtggaacaa aaagatgcaa
    20101 caccagaaga agctcttgta caagaaatca atacaggaac ttactgtttt gacaacgaag
    20161 ctttgttcga tgcgttaagc aaagttggaa caaacaatgc tcaaggtgaa tactatctaa
    20221 cagatatcat cgaaatctta aaagaagaag gccatacagt tgctgcttat caaacggatg
    20281 attttgaaga atcaatggga gtcaatgatc ggatcgcgtt agctaaagca aatgagatca
    20341 tgagaaagcg aattaaccag atgcatatgg tcaatggcgt aagctttgtc gattcagcaa
    20401 cgacatacat cgatgcaggc gtagaaatcg gtccagacac attgatcgaa gcaggtgtac
    20461 aaatccaagg aaatacagtc attggttctg attgtgtcat cgggtcacat tcaaaaatcg
    20521 tagacagtag gattgaggat cacgtcgtca ttgaaaactc agtcattgaa agcagccatg
    20581 tcaagaaaca tgcagatgtg ggaccttatg cacatttacg accaaaagct gaaattggcg
    20641 aaaacgtcca tatcggaaac tttgtggaag tgaaaaatgc tcaaatcggc aaaggaacta
    20701 aagtcggtca cttgacttat gttggtgatg ctacgctggg agaagaaatc aatgtcggat
    20761 gtggtgttgt cttcgtcaac tatgatggaa agaacaaaca tcatacgact gtcggcgacc
    20821 acagctttat tggttctagc acgaatatca tcggacctgt cgaggtagct aaaaacagtt
    20881 cgattgctgc cgggtcaaca attacagaca atattccaga atatgcgctg gcaattgcga
    20941 gagcaagaca agtcaataaa gaaggatatg caaaaaaact cccttatcta aactaagact
    21001 tttgcaaaat cacttgattt atttaaaaaa tatgactact atttattagg tagaattcta
    21061 gagttgtgaa aaagaaagtg gaggtcccca tgtcaaaaca ttactttgac ccaagattaa
    21121 aaatttttgc gttaaattcc aatcgcccat tagcagagaa aattgcagca gcagtcggcg
    21181 tcgagttagg aaaatcatct gttactcaat ttagtgatgg agaaattcaa gtaaacattg
    21241 aagaaagtat tcgtggatcg catgtctatg ttattcaatc aacgagcagc ccagtcaatg
    21301 ataacttgat ggagttgctg atcatgattg acgcactgaa acgagcaagt gcaaaaacaa
    21361 tcaacgtagt catgccttat tatggctatg cgcgtcaaga ccgtaaagca cgtgcacggg
    21421 aaccaatcac agcgaaatta gtagcaaaca tgattcaaaa agctggtgca acaagaatgc
    21481 tgactttgga ccttcatgca gtccaaatcc aaggtttctt tgatattcca gtcgatcatt
    21541 tgatgggtgc gccacttatt gccaattatt tcttagaaaa aggaatcaaa ggcgatgatg
    21601 ttgtcgttgt ttcaccagac catggtggtg tcacacgggc acgtaaatta gcggaatttt
    21661 tgaaatctcc gattgcgatc atagacaaac gccgtccaaa agcaaatgtt gcagaagtaa
    21721 tgaatatcat tggacaagtc aaaggcaaaa cttgtgtact gatcgatgat atgatcgata
    21781 cagcaggtac gatcacattg gctgccaatg ctttgaaaga agctggtgca actagtgtgt
    21841 atgcttcatg tacacatcca gtattatccg gccctgcttt acaaagaata gaagattcag
    21901 ctatcgagcg tctagttgtt acagactcga tctatcttcc agaagatcgt aaaatcgaca
    21961 aaatcgatga agtaagtgtt ggcggactaa tgggagatgc aatcaaacgt atccatgaaa
    22021 acaaaccagt tagtccattg tttgaaacaa aaaataaata ataaataaac tcacaaaggg
    22081 gagtccaatt gggctgagat tgaatctatt tctaaaccct tcgtacctgt atcggttatg
    22141 cgagcgtagg aattgtgaat aaacagctgt ttgactattt tcgaaagctg cttcctcctt
    22201 tgtgactttt ttattcaaag gaggaagttt ttttatggga aaaaatagag tttgggtaga
    22261 aggaacgatt gttgcagcgt tagcgatggt gttgtcgttg attccgatcc agatcggcag
    22321 cagtttttct atttcattag ggcagattcc attgactctt tttgcgttaa gaagagggac
    22381 aaaggcaggg atgctggcag gtttcatttg gggcatccta cattttccgt tgggacaagt
    22441 ttattattta agtgtcgttc aagtgttgat tgagtacccg attgcctata cttttgcagg
    22501 cgcagcaggg ctcatggctt caaatgtcca aaaaggctat gtagacgata atacgaaaca
    22561 aattagaaaa agcatcgtgt ttggtgcatt gattggcgca ctttccagat atttttggca
    22621 ttttattgca ggagtggttt tctggggagc gtatgcacta tgggggatga atccttggct
    22681 cttttctttc gtaatgaatg gtgccagcgg gttgagtaca gctattgtaa cgatcatcgt
    22741 tttattaggg atccaacaaa cgactccttc gatttttgtg ccagataaac gacaggagct
    22801 gtaaataaaa aagaagcaag aaacttgaga cagaatcatg tcctagtttc ttgtttcctt
    22861 tttatttttt gataagaaat agatctactt caatggcaga taagaaagat cggcatcttc
    22921 taccaattgc cagtgtcgat cggtgacaga gtagattaaa gtagcgatga tttcctcttc
    22981 tcgataccgg gtgcctttta atttccaaat ataatcttca atcacataga ttgggatacg
    23041 atatttacca tcgatcaaac caacttgatc aaaagaaaaa atgatccctt cctgcatcaa
    23101 attacgcatt tctttcaata attccacact gattttttca acaggtgttt cttttttgaa
    23161 aaaagatttt tttacattga tcttatctga caagatcgaa cttaatttac tagcaaaaat
    23221 cctataaaat tcatctaaat agcgataata aatccgattc agctgatcat taagatcgaa
    23281 gtatacaaaa ttattctgta gtttataaaa aaacggcgaa tgaagatgtg ttttcatatg
    23341 accaaaatat aataattctg aaatttctaa aggtgtcaat tctttcagca tcgttaaatc
    23401 agtaaagtcg atccacttca attcatcgaa tccacgcctg ttacgagaag aggaaaagaa
    23461 acgctgaata ttttctgtac cacggattac tttcagccct gtatgggatt catattctcc
    23521 agcagaagca gatggatcaa gcaagagcaa gttttgagga aaatgcacga tactgtttgc
    23581 aaagtcagta gcagtcagcc cttttgttaa aacagcatta cttgtggtat caatatgtac
    23641 ataaactgac tcagtcatca tgttcctcct cttatttcct cttaatctct tttattttac
    23701 aacatttgca ttaaaaaagc ttgtttcttt tattttaaaa ttccattaca aaatcacgtt
    23761 ttcattgaaa acactctcat tttcaattaa tttttgtgat ttttgtattt ttttatttaa
    23821 aggaggtttt atgaattgtt ttcttatgga atctacaaag tcgaatacga gactcatgac
    23881 ctttttatga cgtactggta tacttgaaga aaaaggagag cgcgatggag ataaaaaaag
    23941 tttacttttc acagaaaatg tcgctgtatt cgcctatcca gcaagcaaaa caaccccttc
    24001 cattttttca aagtcatcaa gaaagtagag acgctttttg gcgttctgca aaaaagcaat
    24061 gtgcttttaa agcagtatcg aaaaaatata ccgtctattt tactattgct aaaagtagag
    24121 gagatgttat ttttaataat ctgttgattg aaggtgaaac ttttgaatgg aaaaaatttt
    24181 ttcggtatat ggaagcttgc gctcgttttt ttattaaaga aaactgttgt tttttatttc
    24241 aatctcctct atcagaagaa tggttgcgta tttttcataa aaacggctat caaggaacca
    24301 cacaattaaa taaaaagctg gtctatcata cagcacttgt tttaggtgga ggaggagcgc
    24361 acggtgctta tcagattggt gtgtggcagg cgctgaagga acatgatatc aactttgaga
    24421 ttatcacagg tacctcggta ggtgcgttga acggcgcatt gattttacaa ggagatatga
    24481 aaaaagctgt gaatttatgg aaaaagctgt cgacaagaca agtgcttgcg ttaccagaaa
    24541 tggctgcagt tgaagacctt cgtgaacgct tctatcgaga aagacgccaa atgacgaaaa
    24601 cagcactaat tgaaggcggg gtttcttctg ctccattgga aaagatggtc aaagacaatt
    24661 tggatttgtc cttactcaaa cataatccca aaatacgttt atatacggtg tctactaaac
    24721 tgccagaact agcggaagta gtgactgata tccaacagac aaaaacagaa gaaataccag
    24781 attggatact cgcctctgct tcattttatc ccgctatggc ttatcgaaag atcggaaaaa
    24841 ataaatatgc agacggtggg tatcgcaaca aaatacctat tgatattgcg attaacaaag
    24901 gagcaacaga ggcatttgtc gtagatgtgc aagggccagg cccagcgaaa aaaattcgta
    24961 tgccagacat ttttatccat tggaaatgtc aaacattgtg gacactaggc agctttctgc
    25021 tttttgatag ccaaaggaac caattaaatt tacaattagg ctatctggaa atgaaaaaac
    25081 gattaggcta ttactatggg aactggtata catttcattc tgttaaacct gcaagaacat
    25141 actggcgagg atttttgtct tacttaacaa aagaaattca gttagaatta tcttttttca
    25201 aaagcataaa attttggcaa aaactgcgta atttatataa gaacagggtc gtaccagaga
    25261 catgcggatt ggcgatgcta gaacttttag caaaaaaaca ttttttactg cccaatgaaa
    25321 tctatcaagt agacatgatg attcaaatga tctgccaaca agatataaaa agtatgccgg
    25381 atgatttatt ggcacaaatt ggtcaattaa gtactgaaga atggcgaagg tatcgaaaat
    25441 accagcaaaa aatacaaaat gagcgcacga aaactgttta ttttgattat ctgctacaag
    25501 gaaaacgcaa ggatcgtttg cagcatgaat tgcttaagca accagttgac acattactga
    25561 tcctatattt atattatctc aaggaggaac aaccatggca caagaatttt catatgaaat
    25621 cgtagaagaa atcgctatat tgtcagaaaa caacaagggg tggcgtaaag aactgaacct
    25681 agtcagctgg aatggtcgcc cgccaaaatt cgatcttcga gattgggcgc cagaccatga
    25741 aaaaatgggg aaaggcctga cattgacgaa cgaagagttt gaacaactgc aaaaagcaat
    25801 agaaaatatg taatgaggaa ggaccctgtc gaatgaaaag tatgactggt tttggcaaag
    25861 ccatccgcga aacaaaagcg tatcagttag atattgaaat aaaaagtgtc aaccagcgtt
    25921 ttctagatgt tcaaatacga agtcctaaaa tcctgaactt tgttgaaaac gattttcgtc
    25981 agcttattaa acagcagtta agccgcggtc gaatcgaagt atttgtgaat ctagcttata
    26041 ttggcaaaaa cgaaaaacag atcgtcatca actgggaatt gattgattca cttatcactc
    26101 aattgacaga cggaattcaa caacgatacg gtagtcaaaa tcaagtgtca attagtcgga
    26161 tggcggaacg cttcgtgctg gacgaaaact tcgtaacggt agaagaaaaa ccggaagaga
    26221 gcatggaaga attggcacag ttagctctag atacattgaa aagcgcactt gattctattg
    26281 aggcgagtcg agaaaaagaa ggtcaagctt tagctttagt gttgaaaaag aatactgaag
    26341 aattcaaaga agtactaaaa aaactcgata gttttgtaga aatctatgaa aaggaatttc
    26401 aaataaggta tcaaaaaaag ctggaggaat ttcttggagc gaaagtcgat gagcaacggt
    26461 tgttgacgga gctagccatc ttgttggaac gcggagatat tcacgaggaa ctggatcgtc
    26521 tggcgatcca tgtacaaaaa ctagatgaac ttatcgaagc acaatgtcct gtaggtcggg
    26581 aattagattt cctgatccaa gaaatgaatc gggaaatcaa cacgatcggt tccaaatcaa
    26641 atgcaatcga aattaaaaat caagtcgtcc agtctaagac gatcttagaa aaaatcagag
    26701 aacaagtaca aaatattgaa tgacgaaaga ggtagagata atgaaatatt atgacgtaac
    26761 gttccacgaa ttaagtggaa aaactgtggt taaacgggat atcccttctg aaaaaaacgg
    26821 ctttgacgta tggaaagatg cctgtgcaga ctataatgag aacgaactgt ttattttgat
    26881 caacgacggt gcttacgtga cgatgaatcg gaaatttatt gttcgaattg acacagaaga
    26941 ggtagaagat ccgacagaaa aagcacgttc tcgaaaagat gagatcatgg gtgtagtgaa
    27001 tactttgtcc aatatgggct tttagcaagg atgctgaaca aagaaataca ataaataaac
    27061 agaattggat ttcttcgctt agcttctttg ctctaggaat acatttaaag gttgtgacaa
    27121 aattcgtgtc acaatctttt tttattttga ataagtgatg ttcaaaaacc attttctcgg
    27181 tattaagcca aatttatgca aaaatgtgag aaactatttt cacaaaattt ttcttcatac
    27241 tcgaaactaa tcggcttctt cacgacctct tatacacggc gttcaaaagc ttgcatctgc
    27301 gataataacc ccaaccaaac gaaaaacatg agaagctgtt tatgtttggc tgttcttatt
    27361 acttgatgca ggacagcttt tttacgacct cttggtacag ggtagctttt ttaccaattt
    27421 ctagctataa ttaaagataa ccttgaaagt tgcagaaaaa aagtgcaaaa taaacgataa
    27481 gtacaaaaag actagttgaa aggacgtcgt catgtcagag cgtggattat taatcgtgtt
    27541 gtctggtcca tccggtgtag gaaaaggcac agtacgaaaa gcaatttttg agagtgagga
    27601 taatgatttt cagtattcga tctcaatgac tacccgtaaa atgcgtgaag gggaggtcga
    27661 aggcgttgat tatttcttcc gaagcaaaga agagtttgaa tcaatgatcg aagctggaga
    27721 gatgctggaa tacgcagaat atgtcgggaa ttattatgga actcctttgt catatgtcaa
    27781 caagacattg gatgaaggaa aagatgtttt cttggagatt gaagtccaag gagcaaaaca
    27841 agtcaaagaa aaagtgcccg atggtgtatt catctttttg actccgccag atttagcgga
    27901 attaaaatca cggatcgtag gccgaggaac agatgcagat gaagtaatcg aaaaacgaat
    27961 gaaagttgca aaagaagaaa tcgaaatgat ggctctttac gactatgctg ttgtaaatga
    28021 tgaagtgccg ctagcagttg aacgaatcaa aaacattatt gccagtgaac attttcgagt
    28081 agatcgcgta atcggtaaat atattaaaat gttaaaggag atgtagtctt atgatgttaa
    28141 aaccttcaat tgactcacta ttagatcgtg taaattcaaa atattctcta gtgattttag
    28201 caagtaaacg cgcgcatgaa ttggatgcaa gtgcacagcc tactctagat tcttttgatt
    28261 cagtaaaaag cgtcggtcaa gctttagaag aaatcgatgc aggaaatgta gtcaatgatc
    28321 cacatcctga attaaaacgt gaacgtttga agatggaaga agaggaacgt caagcacaaa
    28381 aagagcgtga acaacacgaa ttggaatcac gtatccgtga agagcaaaaa atgtaataaa
    28441 gaaaaataga gcgaacatct aaaaagaaaa gcaaacccag ctgtttcctt ttcaaacatt
    28501 cgccacttat tgtctggtag aaaaggctgt gtctgaactt tttgacacag ttcttttttt
    28561 tcttatctgc tgttaatttt ttgttaggat ttggcagaag ataagacaaa tccatcgatc
    28621 tctagtaaaa taggcaagga actttttgtc gcttgataag aaaagacaaa aaaaggagga
    28681 aacgaaccat gacattaaca gctgaagtca ttgtggacgt acctactatg cagaccgatc
    28741 agccattcac ttatttggtt ccctctgaaa tggaaacagc tttgcaagtc gggatgcgag
    28801 tagaagtccc ttttggtaat ggcaatcgtc atgtccaagg atttgttatg gctatccaaa
    28861 aatcagaaga atcagctaat ccatctttga aggcagttat tcgtttgcta gaccttgctc
    28921 cggtggtcaa tgaagaatta ctttcattag ctgattatat gaaaaaaatt acttacgcat
    28981 tcaaaatcac ttgtctacaa acgatgcttc cgagtgtgat gaaagcagaa tatgataaat
    29041 tgatctatcc tttggcagac acaccagaag ttcaggtatt gtttgatcag cgagaagtga
    29101 tttcctggaa ggaagcagaa gaagaaggca gcctttctca attgattcgc tggcgccaag
    29161 agcaattagt agatatcaaa tatgaagtcc atacacgaaa taaagtaaaa acgattcgtt
    29221 tggtccgttc tttgttaact gaaaagcaaa tcgaagaaga atgggcaaaa ttacggcaaa
    29281 atgccaagaa acaaaaagaa cttcttttgt gtttatctga actgagccaa gaagaaccaa
    29341 ttgcttattt caaaaataaa ggaatcagta ctgctgtctt gaatcaagga aaagaaaagg
    29401 gctggctgga gtttatagaa tcagaacgtt atcgcgaccc ttataaagac cgagtatttg
    29461 accaaacgac ggcattggaa ctgaatgcag aacaaaaaaa tgctgtcgaa caaatcatca
    29521 cagcaggtca gcagcaaaaa gatcaggtct ttttgctgga gggaatcact ggcagcggga
    29581 aaacagaagt atatcttcag gcaatcgctg atgttttgtc agaaaataaa acggctatta
    29641 tgttagtgcc tgaaatcgca ttgactccgc aaatggtcga gcgattcaaa ggacgcttcg
    29701 gagaatcagt tgcggtctta catagcggac tttcccaagg tgaaaaatat gatgaatggc
    29761 gcaagattga gcgggaagaa gcgcaagtag tagtaggcgc acgatctgct atttttgccc
    29821 cgctgaaaaa tatcgggctg atcattatcg atgaagaaca tgaatcaagt tacaaacaag
    29881 atgagacacc gcgttatcat gcgagagatc tagcaatttg gcgcagtaaa tatcatcatt
    29941 gcccaatagt tctaggaagc gcgacgccct ctttagaatc aagagcacga gctcaaaaag
    30001 gcgtttatca gttattgcag ttaaaccacc gagccaaagc agctgcacag cttccagcta
    30061 ttgagatcgt agatatgcgt gaagagtttc agaatcatcg gacctctact ttttctgcta
    30121 atttgcagga aaaaatacaa aatcgattag acaaaaaaga acaaactgtc ctactgctca
    30181 atcgtcgagg atattcgtct tttgtgatgt gtagggactg tggatttgtt cttccatgtc
    30241 ctaattgcga tatctctctt acactgcata tggatacacg ttcaatgcgc tgccattatt
    30301 gcggacatga agaacctatt cccaatcgct gtcctaattg tggcggcaat aaaatccgct
    30361 actatggaac aggtactcaa aaagtagaag aggaactccg agaactttat ccgcaagcta
    30421 ggattttgcg tatggatgta gataccactc gaagaaaagg ggcacacgaa cagattttac
    30481 aaaaattcgg tgcaaaagaa gcagatatat tattagggac acaaatgatt gctaaaggtt
    30541 tggactttcc agaagtgaca ttagttgggg tgttgaatgc tgatacctcc ctgaatttac
    30601 cggattttcg ttctagtgag catacattcc aattgcttac ccaagtttca ggacgagcag
    30661 ggcgagcgga aaaagcaggc gaagtcgtga tccaaacatt caatcctcaa cattacgcca
    30721 tagaattggc taaaaaacaa aattatgagc agttttatca gcaggaaatg catgtacggc
    30781 atcgtggagg ctatcctcct tattacttta ctgtgaaaat aaccgccagc catcctgaag
    30841 aacaagtagc ggcaaagaaa atctttcaga ttgccaatca gctaaaagaa gtgttaagcc
    30901 ctcaaagctt gctattaggg ccaacgccca gcatgatttt gagagtgaaa aaccgatatt
    30961 attatcaact aatcatcaaa tataaacatg aaccgaatct tcctcatgtt ttggatgaaa
    31021 ttttgaatgg aagccagaaa gaacagcgac aaggtctttt tgtggcaatt gacaacgaac
    31081 cattaaactt tatttaagaa agggccaaat tatgcgctat cctatattga tccaccctaa
    31141 tgataaatta aaaagaactg ctcagccaat cgatgtaatc acggacgaga caatcgcttt
    31201 attagacaat ttatatgaga caatgattgc gaatgacgga atagggatcg ctgctcctca
    31261 agtaggacaa aacaagagaa ttgctgtgat cgaagtagat gaaggcgaga aatttgaact
    31321 gattaaccca gaaatcatcg aagcaaaagg tgaaagcctt gacgtagaag gttgtctcag
    31381 tattccgcat gtctatggaa cggtcaagcg agcagatgaa gtgaccgtgc gttattatga
    31441 tcgagacgga gaagagatag aagtgacggc ttttggctat ttagcccgtg ccttccagca
    31501 tgaaatcgat cacttagacg gtatcttgtt cattgagaaa atgatacagc agatcccgga
    31561 agaagaactt gaagaatata tggaggaaca tcttgatgac taagctagta tttatgggca
    31621 cacctgcttt ttctgtgccg attcttgaag ggctgataga atcaggttac gagatccagg
    31681 cagtggtaac acagcccgac cgtccagttg ggcggaaacg agtaattacg ccgacaccgg
    31741 taaaaaaagc ggctctgaag cacggtatcc gtgtgctgca gccagagaaa atctccggtt
    31801 cgccagaaat ggaagaaatc attgaattgg tgcctgatgt gatcgtcact gcggcatttg
    31861 gccaattctt gcctgaaaag ttattgcaag taccaaaatt aggggcaatc aatgtccatg
    31921 cttctttact tcctaaatat cggggaggtg cgcctgttca ttatgccatc atgaatgggg
    31981 agaaagaaac tggtgtaacg atcatggaaa tgatcaaaaa aatggatgca ggcggaatct
    32041 atgcgcaaga aagcatacca atcactaaac aagatgatgt agggacgatg tttgaaaagc
    32101 ttagcctttt aggaagaaag ctattgctag aaacattgcc caatattttg gatggacaaa
    32161 aaccagtacc tcaagacgag tcagaagcaa ctttttcgcc aaacatcaca cgggaacaag
    32221 aagcaatcga ttggcataaa actgcagaag aaattgacaa ccaagtacgc ggaatgcgtc
    32281 cttggccaat tgcattcacg acctatgagg gcatacgctg gaaattatta tcggttgaag
    32341 tattggcaga aactacagac aaagcacctg gtacgatcat ccggaaagac aaaaaaaatc
    32401 tatggattgc ttgcggtaaa cagaccgtct tagccatcaa tgaattacag ccagctggta
    32461 aaggaaaaca ggccgtacat gatttcctta acggaagcgg tcagcaagtt cagattggtc
    32521 agcaggtgaa ataatgaaaa aaatccctaa aaaaatgaaa aaatcagtac gatatatggc
    32581 attactgaca ttagagcgag tgaacaaggg tggcgcctac tcgaatcttt tgttgaatga
    32641 gatgatcaaa caaagcgagc taaatcaaaa agatgtgggt ttatttacag aattgatcta
    32701 tggtacgatt agccatcagc gactattgga attttacgtt gcaccattga tcgctaaagc
    32761 aaaaaaagtg gatgactggg tcaagatgct tctttatctt tctgtatacc aattagaatt
    32821 tttagataaa gtccctgcac atgctatttt aaacgaggcg gtcgaaatcg caaaagtaaa
    32881 aggaaatcct gggacaggga aatttgtaaa tggtgtcttg aggaattatc agcgtcaagg
    32941 agcaccagat ctgcaaggca ttgctgatcc tatcgaaaga ctttctgtca aaatcagcct
    33001 gcctctatgg atgacgaaac gactggtgga tcaaatcgga tacgaagaaa ctgaaaagct
    33061 cggtttatcg ctatatcagc ctagccatgc tagtgcccga gtagatacac gccgactttc
    33121 cagagatcag gccatcactg ttttgcaaga agaagagatc acagctgaaa aaagccaagt
    33181 cagtccatac ggtatagtag cgaaaaaagg gcatttagct tctagctcat tgttccacga
    33241 tggcgtcatg acgatccaag atgaaagttc gatgcttgta gcgccgtcta tgcaaatcga
    33301 gcctgaacat catgtcttag atgcctgtgc agcacccgga ggtaagacga cgcatattgc
    33361 ttctttttta gatccgtcat gcggtggaga agtggtcgct ttagatgtac acgaacacaa
    33421 agtcaaactc attgaagata atgcagcacg tctaggtgtc tcttctgctg tctacgctca
    33481 aaagatggat gctagagaag tcagtaaaca gttcgaagca gagcagtttg atcggatttt
    33541 agtagacgcg ccttgttcag gtcttgggct gcttcggcga aaaccagata ttcgttataa
    33601 aaaacagccg gatgaattag cgaatttacc aaaaatccaa ttggaaattt tagaaagctg
    33661 cgcaccaact ttaaagtctt ccggtattct gacttatagc acttgtacga tcttaaaaga
    33721 agaaaaccaa gacgttgttt ctgctttctt ggaaagacac cctgattttg agaggattga
    33781 tgttttgacc aatcctatgc tacaatcatc aatcgaagag aaaatgttga ctttgtatcc
    33841 gcatcagttt tacacagatg gatttttcat ttgttgtttg cgcaaaaagt aatgaggtga
    33901 aaaaatgcag attgaatatc aatcagatgt aggaagacga cgtaacacaa atcaagacta
    33961 tgccagtgta tttaccagcc gttcaggtct caagcttgct gtattagcag acgggatggg
    34021 tggtcatcgt gccggagaca ttgccagtca gatggcggta acgaatctag gcgaagcttg
    34081 ggaaaaacaa gaagctgttg acgatgaaaa aatcgcccaa tggttcattc aatcgattca
    34141 agaagaaaat atgctgattt atcagcgtgg acaagaacag ccggaatata acggtatggg
    34201 aacaacaatc gtagcggccg ctctgtcaga tgactggttc acgattgcca atgttgggga
    34261 tagcagagct tatttgattc gtgaagataa aatcatgcaa ttgacggagg atcattcttt
    34321 agtcaatgaa ctagtcaaat caggagaaat cagcgaagaa atggcagtga accatccaag
    34381 gaaaaatatt ttaacacgtt ctgtcggcat gcctggaaca gtcgaagtag atgtttctac
    34441 tcatctttgg caactaaaag atcgactgct gttatgttca gatggcttga cgaacatgct
    34501 gtctgaagaa gaaataggaa cgatcatcaa tcaagaaggc ccattgtctc ataaagtaac
    34561 tgagctgatt gatcgtgcca atgaagcagg cggagcggat aatatcaccg ttcttcttat
    34621 cgaatataag gaggacagtg tatgatcgag ttgggcaaaa aattaaatgg ccgttatcaa
    34681 atcactggaa atatcggtag cggtggtatg gcaaatgtat ttttggcgca cgatttaatc
    34741 ttggatcgtg atgtagcagt taaagtctta cgatttgact ttcaaaatga ccagactgcg
    34801 attcgacgat ttcagagaga agctttagca gcaacagaac tcgttcatcc aaacattgtt
    34861 agtgtttacg atgttggtga agaagacaac atgcagtatc tggtgatgga atacgtcaaa
    34921 ggaatggact tgaaacgata tatccaaaca cattatcctg ttccttatga aacagcagta
    34981 aatattatgc agcagatcct ttctgctatt tctttagctc ataaccatca aatcatccac
    35041 cgagatttga aaccccaaaa cgtactgatc gataatgaag gtgttgtaaa aatcacggat
    35101 ttcgggattg ctatcgcttt atctgaaaca tcgatcacgc agacgaatac gatgctagga
    35161 tctgttcatt atctgtcccc tgagcaggcc agaggaagta tggcaacgaa gcagtcagat
    35221 atttatgctt tagggatcat cctttatgag atgttgacgg gtagcgtacc gtttgatggt
    35281 gaatctgctg taacaattgc tttaaaacat tttcaagatg atcttccatc tataaaagca
    35341 cttgatccaa atgtgccaca agcactggaa aacgtgattt tacgggcaac ggctaaagaa
    35401 cctgcagacc gttataagtc agccgaggaa atgtctgatg atctttctac agtattatca
    35461 ccagctcgtg caaacgaaga aaaatggcag cctcatgtga tggataatga aacaaaagtt
    35521 atcacacccc ttacggaaga tgcaccaatg cctgattcat tcaaatctat gcctctgcca
    35581 aaagacaagc cagaaaacga aaccttacca gaggaggaag aagttctgcc tgatcctaaa
    35641 aagaaaggac agaaaaaatg gtggctgatc ctattagcta ttcttgctgt tttaggaatc
    35701 ggaacagctg tattctttgc ttctggcggg cgaggagaag ttgttgttcc tgatgtttct
    35761 gatctttctg aagcttctgc tagagaaaca ctcgcaaaag cgaaattaga agtagcaaca
    35821 aaaacagaag aaattgcaga tgacaaaatc gaagaaggta atgtagtgaa gacagacccg
    35881 gcagcgggaa cgacagtcaa gcaaaaacgc gaagtcactc tgtatattag tagcggcacg
    35941 aaaaaaatca aattagatga ttacagtggt aaaagttatg aagatgccga agcaagtttg
    36001 aaagaattag ggttttctgc tgacttgatt caaaaagaag aggaattcag ttcagaggta
    36061 gaaagcggaa tgatcatttc gcaatctcca tcagaagata cagaagtcga tcctaaaaca
    36121 gacacgatta ctttcacagt cagcaaagga ccagaaacag tgactttgag tagtcatgta
    36181 ggagaaaact acgaaactgt tcgtaattgg cttgttacac aaggattcaa tatcaataat
    36241 attagtgcta cttatgacta tagcgacact gtaccatcag gttcgatcat cagtcaggat
    36301 ccagcctcgg gtgaagttgt agcagaagaa acttacatca attttgtcgt aagccaagga
    36361 acagagccta aattgaatga tatctccggc tatacaaaaa gcgaagcaca aagttattta
    36421 gctagtgtcg gtgcagaata tatcgggcat gagacttccg aatattcaaa cacggtggat
    36481 aaagataaag tgattcgtac agtaccaggg gcaggaacga caattaccaa aggaatggtt
    36541 gtgaacgtaa tttactctaa aggaccagat ccagcgtctt ctagttctga aaaagactct
    36601 tcagacagtt ctagcagctc aagtagctcc agtagcacaa gcaactcttc aaaagaagaa
    36661 tcttccagct ccacaagttc atcagctagc acctcagaaa gttcaaaata agtgctgaat
    36721 aaaatatatc agaagggaat gcgacattga tttgttgcat tctctttttt gtgtttctat
    36781 ctcttttgat caattttcaa gccatatact ttgagaagtt tgcatggaat aacacctact
    36841 ttcctcttcg tatggtaaaa taaacaaaaa cggaggtggc acttatcaaa ggacaaatca
    36901 gaaaagcaat cagcggtttt tactatgtat acgcaaacgg agagacctat caaacaagag
    36961 gaagaggaaa tttccggaat cggaaaatca cgccgcttgt cggagatcag gtgatctttg
    37021 agagtgaaaa tcaaacagac ggctatcttc tggaaatctt gccgagaaaa aatcaattag
    37081 ttcgcccacc agtcacaaat gttgatcttg gaatcattgt cacaagtatc gtagagcctg
    37141 cattttctta taatctactt gaccgctttc tagttacctt ggaatacgag tcgatcgaac
    37201 cgattatttt tttgacaaag accgacttgt cagacgaccc agaaaaaatc gaagagatca
    37261 agcaaaccta tactaaaata ggctatccgg tgattgtacc caatcatacg ggtgatacga
    37321 cagaactgat ccgttacttc ccagaacggc tatcggtctt tatgggtcag tctggagcag
    37381 gaaaatcgac gctactgaat caaatatcac cggaactgaa tttagcaaca ggagagattt
    37441 ctgatgcact tggaagagga cggcatacaa cacgtcatgt ggaactgatt cctatctatg
    37501 gcgggttagt agcagataca ccaggattta gctcgattga ctttttgaca attgaagcag
    37561 gagaactgcc gagacaattt cctgaatttg tagaagcttc tgtccattgc aaatttagag
    37621 agtgcatgca tgctaaagaa cctggctgcg aagtaaaaca tagagtagaa acaggtggta
    37681 tcgcacagac acgttacgac aattatttgc aattcttaca agaaatcgaa aaaagaaaac
    37741 caatgtatgc aaaaaaagaa ggtaaacgaa aataggagga aacaagaatg aagatagcac
    37801 catccatttt gagtgcagat tttgccaatt tacaaagaga cattgagtta gtggaaaaag
    37861 gaggcgcaga ttacatccac gtagatgtaa tggatggccg atttgtccca aatatcacat
    37921 tagggccaaa tattgttcag gcaatccgtc ctgttactaa attaccgtta gacgtccatc
    37981 tgatgatcgt tgatccagaa aactacattc cagcatttgc aaaagctgga gcagatatca
    38041 ttactgtcca cgtcgaagca actcctcata ttcatcgggc acttcaaatg acaaaaagct
    38101 taggagttaa agctggagta gttatcaatc caggaacacc agtctccatg atcaaacatg
    38161 ttttgccttt ggctgatcaa gtactagtca tgactgtcaa tcctgggttc ggcggacaaa
    38221 gctttattga agaaacagta gaaaaaatta cggaactcgc tgatctacgt agagagaaca
    38281 attggactta tgcaatcgaa gtagatggcg gaatcgttcc agaaacagca aaaatctgta
    38341 aagatgcagg ggcggatgtc ttcgttgcag gatcatatat ctatggagcc gaaaatccag
    38401 tcggacaaat cgaacgatta aaagaggcat tagactaaat gaaaatttta ttagctgctg
    38461 gaggtaatcc gcaaaactgg ccgcagtctc tgctgtccaa atacgatgcc tatgtcggga
    38521 tagaccgtgg tgcgctgtac ctgcttcaag caggctaccc agtagatctg gcagtgggtg
    38581 attttgattc attgtcgaac gaagagcaga aggaagtatt tgcaaaagcc aaagagtata
    38641 cccgttcccc tgcagaaaaa gacgatacag atacacagtt aggtatctta aaaacatttg
    38701 aacgttaccc gcaagcggaa gtcactttga ttggagctac gggcggaaga ttggatcatc
    38761 ttttagccaa tctctggtta ggtatggaac ctcgcttcaa accctttgcc catcagctta
    38821 ttatcagaga ttgtcaaaat tatttgtctt attatttgcc tggagagcat atagtaagac
    38881 agataccaga tatgaagtat ttagcttatt gctgcttgac tcccgtctcg aatcttacat
    38941 taaaaggcag caagtatgta ttggaaaata aagaagtaga atatccgaca tcttatgcaa
    39001 gtaacgaatt tctttcagat accgcagaat tttctttttc agatggtatg attgcagtta
    39061 ttcaaagcaa agattgatcc ataaacaaat aaaaaaattt gtctttcagg ctaaaaatga
    39121 cagaatctat tatttgctaa aaaaaagctt aagaggagca acttaccttt tgtttcacgg
    39181 catttagtga taaaattgaa cacaagagtc taattaattc gaggtgtctt tgtgaagaag
    39241 ttcaatccta ataaaaatat tattattacc ttggttattg ttatcatcgt ggtgacgata
    39301 ctaagtgtga ccgctgcgca gcgagcgaat gaaggaaagc ccaatttctt ccaatccatc
    39361 gttaatgaca gtgttgcaat ggttgataaa acaatctctg ccccagtacg gtgggtacga
    39421 aatggagtag attctgtcca taatcttttt tcaacttatg ccgaaaatga gcggctaaaa
    39481 gaaaaaatcg atagctatga tgacgtttca cagcaaaaca agaattacga gagagaaatc
    39541 gaagcgttga aaaaagaact tgagttgaat cagacgctga ctagttacga aaaagtaacg
    39601 gcaaatgtca ttactcgttc gcctgacagt tggcaggaca tgctgatcgt agacaagggt
    39661 tctaaagacg gtatcgaagc aaatatggca gtcatgtcgc aaaaaggatt gattggccga
    39721 gtgatcgagg tcaatacggc ttcgtctaaa atcgaattac tgtcatcctc taatgaaagc
    39781 tccaatcatt ttccagtacg ggtatcttcg gctaatggcg aagcgtttgg tttgcttaaa
    39841 aactatgatg aaaagctcca tgccttagtg gtgacccaat taactggtga tacggatatc
    39901 aaagaagggg atgttgtcca gacatccggt cttggaggga attctccagc taacttgccg
    39961 atcggtacgg ttattaaaac gaaaccagat agttatgggc tggatcggga agtttatgtg
    40021 aaaccttatg cagaaatgta tgacgtgtca gttgtgacga ttgtccaacg gctagcggag
    40081 gattagtcca tgttgaagaa agaaacaatg aagtactatc tgccaatcgt tttgttcttt
    40141 ttgatgttga tagatggtca tttaacaaga atgctagggg agtggtcgaa aggcacctat
    40201 atgtcaaatg cccactttct gatattggca ttattatgtt gcagtatggc gtttgaaaaa
    40261 cgttatttac tgattaccac gattgttctc ggggctatct atgacgctta ctatattggc
    40321 gttatcggta tctatgcagt agctctccct ttaattgtat ggttgatgta tgtaatgaaa
    40381 gacgttatcc atgtcaacat ctttactgaa tttttcagta tgatcatctt tgtcacgggt
    40441 tatgaattgt ttacgatggt ggtccagttg atttttaaat tagcagtagt aaataacacg
    40501 tattttatta caaggttttt aggacctaca ctgctgttga acatgattat atttgtatta
    40561 ttcatttttc cctttaagaa attattcagt gatgaataat ttcttttttt atttttaggt
    40621 cgaaagcgaa aaagaatcgt tgttatctta agaaatgcta gacttaacgc ggctttttca
    40681 tgatcatttt ctgaaacgaa cagttttgtc atttttaaaa gttgttttga aacatttttg
    40741 taacataact attatatcgt tgacacactg ctatggtaca atttttatat cgttaagaaa
    40801 gacttaaata tatttagata tttattaaat taagccagtc ggaggaatga agagtgaaaa
    40861 agagtttaat atcagcagta atggtatgtt caatgacctt gactgccgta gcatcaccga
    40921 tcgctgccgc ggcggacgat tttgattctc agatacaaca gcaagatcaa aagattgcag
    40981 acttgaaaaa tcaacaagca gatgcacaat cacaaatcga tgccttagaa agccaagttt
    41041 ctgaaatcaa cacacaagca caagacctat tagcaaaaca agatacattg cgtcaagaat
    41101 ctgcacaatt agtaaaagac attgcagatt tacaagaacg tattgaaaaa cgtgaagata
    41161 caatccaaaa acaagcacgc gaagcacaag taagcaacac aagctcaaac tacatcgatg
    41221 ctgtattgaa tgctgattca ttagcagatg ctattggacg cgttcaagca atgacaacga
    41281 tggtaaaagc aaacaacgac ttgatggaac aacaaaaaca agataaaaaa gctgtagaag
    41341 acaaaaaagc tgaaaacgat gctaaactaa aagaattagc tgaaaaccaa gctgctttgg
    41401 aatctcaaaa aggcgatctt ttatctaaac aagctgattt gaacgtactg aaaacttcat
    41461 tagctgctga acaagcaact gctgaagaca agaaagctga cttgaaccgt caaaaagcag
    41521 aagctgaagc agagcaagct cgtattcgtg aacaacaacg tctagcagaa caagctcgtc
    41581 aacaagctgc acaagaaaaa gctgaaaaag aagcacgcga acaagcagag gctgaagcac
    41641 aagctactca agcttcatct actgcacaaa gctcagcaac agaagaatca tcagctacac
    41701 aatcttcaat gactgaagaa tcatcatcag ctacacaatc ttcagcaaca gaagaatcaa
    41761 caacacctga atcttcaaca gaagaatcaa cagcgcctga atcttcagca acagaagaat
    41821 caacaacagc gcctgaatct tcagcaacag aagaatcaac aacagtgcct gaatcttcag
    41881 caacagaaga atcaacaaca gtgcctgaat cttcaacaac agaagaatca acaacacctg
    41941 cgcctacaac accatcaaca gatcaaagtg ttgatacagg aaacggcaca ggaagtagta
    42001 ctccggctcc aacgccaaca ccaacacctg aacaaccaaa acctgtaaca cctgctccag
    42061 ctccttctgg aagtgtgaat ggtgcagcaa tcgtagcaga agcttacaaa tatattggta
    42121 ctccatatgt ttggggcggt aaagatccaa gtggctttga ctgctcaggg ttcacacgct
    42181 atgtttacat gcaagtaact ggtcgtgaca tcggtggttg gacagttcct caagaatcag
    42241 ctggaacaaa aatttcagtt tctcaagcaa aagctggaga cttgttattc tgggggtcac
    42301 aaggcggaac ttaccacgta gcgattgctt taggcggagg acaatatatc catgctcctc
    42361 aaccaggcga aagcgtaaaa gttggttcag ttcaatggtt tgcccctgac tttgctgtca
    42421 gcatgtaaga atga
//
LOCUS       DAFLWC010000013        42191 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.013, whole genome shotgun sequence.
ACCESSION   DAFLWC010000013 DAFLWC010000000
VERSION     DAFLWC010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42191
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.013"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(12..617)
                     /gene="dhaL"
                     /locus_tag="L1V17_000677"
     CDS             complement(12..617)
                     /gene="dhaL"
                     /locus_tag="L1V17_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HBN1235463.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(645..1655)
                     /gene="dhaK"
                     /locus_tag="L1V17_000678"
     CDS             complement(645..1655)
                     /gene="dhaK"
                     /locus_tag="L1V17_000678"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HBN1235464.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(1630..2076)
                     /gene="dhaM"
                     /locus_tag="L1V17_000679"
     CDS             complement(1630..2076)
                     /gene="dhaM"
                     /locus_tag="L1V17_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HBN1235465.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            2179..2499
                     /locus_tag="L1V17_000680"
     CDS             2179..2499
                     /locus_tag="L1V17_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBN1235466.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(2611..3480)
                     /locus_tag="L1V17_000681"
     CDS             complement(2611..3480)
                     /locus_tag="L1V17_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBN1235467.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(3576..4880)
                     /locus_tag="L1V17_000682"
     CDS             complement(3576..4880)
                     /locus_tag="L1V17_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1235468.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(4877..5386)
                     /locus_tag="L1V17_000683"
     CDS             complement(4877..5386)
                     /locus_tag="L1V17_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235469.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(5561..7696)
                     /locus_tag="L1V17_000684"
     CDS             complement(5561..7696)
                     /locus_tag="L1V17_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1235470.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(7779..9434)
                     /locus_tag="L1V17_000685"
     CDS             complement(7779..9434)
                     /locus_tag="L1V17_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBN1235471.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(9436..9750)
                     /locus_tag="L1V17_000686"
     CDS             complement(9436..9750)
                     /locus_tag="L1V17_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBN1235472.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            9920..10180
                     /locus_tag="L1V17_000687"
     CDS             9920..10180
                     /locus_tag="L1V17_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBN1235473.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            10194..10508
                     /locus_tag="L1V17_000688"
     CDS             10194..10508
                     /locus_tag="L1V17_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBN1235474.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(11238..11792)
                     /locus_tag="L1V17_000689"
     CDS             complement(11238..11792)
                     /locus_tag="L1V17_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBN1235475.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(11918..13847)
                     /locus_tag="L1V17_000690"
                     /pseudo
     CDS             complement(11918..13847)
                     /locus_tag="L1V17_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(14153..14869)
                     /locus_tag="L1V17_000691"
     CDS             complement(14153..14869)
                     /locus_tag="L1V17_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBN1235476.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(14870..16693)
                     /gene="glpO"
                     /locus_tag="L1V17_000692"
     CDS             complement(14870..16693)
                     /gene="glpO"
                     /locus_tag="L1V17_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HBN1235477.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(16707..18203)
                     /gene="glpK"
                     /locus_tag="L1V17_000693"
     CDS             complement(16707..18203)
                     /gene="glpK"
                     /locus_tag="L1V17_000693"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBN1235478.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(18339..19799)
                     /locus_tag="L1V17_000694"
     CDS             complement(18339..19799)
                     /locus_tag="L1V17_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1235479.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(19789..21084)
                     /locus_tag="L1V17_000695"
     CDS             complement(19789..21084)
                     /locus_tag="L1V17_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBN1235480.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(21416..22093)
                     /locus_tag="L1V17_000696"
     CDS             complement(21416..22093)
                     /locus_tag="L1V17_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HBN1235481.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(22123..23214)
                     /locus_tag="L1V17_000697"
     CDS             complement(22123..23214)
                     /locus_tag="L1V17_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HBN1235482.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEKAYKELYLPSPLYNFLKARYQ"
     gene            complement(23315..23749)
                     /locus_tag="L1V17_000698"
     CDS             complement(23315..23749)
                     /locus_tag="L1V17_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1235483.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(24333..25790)
                     /gene="ascB"
                     /locus_tag="L1V17_000699"
     CDS             complement(24333..25790)
                     /gene="ascB"
                     /locus_tag="L1V17_000699"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBN1235484.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(25787..27682)
                     /locus_tag="L1V17_000700"
     CDS             complement(25787..27682)
                     /locus_tag="L1V17_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1235485.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(27740..29515)
                     /locus_tag="L1V17_000701"
     CDS             complement(27740..29515)
                     /locus_tag="L1V17_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBN1235486.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(29565..31061)
                     /locus_tag="L1V17_000702"
     CDS             complement(29565..31061)
                     /locus_tag="L1V17_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBN1235487.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(31255..32877)
                     /locus_tag="L1V17_000703"
     CDS             complement(31255..32877)
                     /locus_tag="L1V17_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBN1235488.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(33205..34518)
                     /locus_tag="L1V17_000704"
     CDS             complement(33205..34518)
                     /locus_tag="L1V17_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBN1235489.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(34763..34987)
                     /locus_tag="L1V17_000705"
     CDS             complement(34763..34987)
                     /locus_tag="L1V17_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235490.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(35007..35429)
                     /locus_tag="L1V17_000706"
     CDS             complement(35007..35429)
                     /locus_tag="L1V17_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HBN1235491.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(35571..36281)
                     /locus_tag="L1V17_000707"
     CDS             complement(35571..36281)
                     /locus_tag="L1V17_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235492.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(36299..36796)
                     /locus_tag="L1V17_000708"
     CDS             complement(36299..36796)
                     /locus_tag="L1V17_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1235493.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(36833..37285)
                     /locus_tag="L1V17_000709"
     CDS             complement(36833..37285)
                     /locus_tag="L1V17_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1235494.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(37420..38025)
                     /locus_tag="L1V17_000710"
     CDS             complement(37420..38025)
                     /locus_tag="L1V17_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBN1235495.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(38475..39095)
                     /locus_tag="L1V17_000711"
     CDS             complement(38475..39095)
                     /locus_tag="L1V17_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBN1235496.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(39097..39966)
                     /locus_tag="L1V17_000712"
     CDS             complement(39097..39966)
                     /locus_tag="L1V17_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HBN1235497.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(39989..40396)
                     /locus_tag="L1V17_000713"
     CDS             complement(39989..40396)
                     /locus_tag="L1V17_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBN1235498.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(40415..41704)
                     /locus_tag="L1V17_000714"
     CDS             complement(40415..41704)
                     /locus_tag="L1V17_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1235499.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
     gene            41762..>42191
                     /locus_tag="L1V17_000715"
     CDS             41762..>42191
                     /locus_tag="L1V17_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBN1235500.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRA"
BASE COUNT        11945 a         9047 c         7118 g        14081 t
ORIGIN      
        1 ttttattgaa cttaaggttg attgatcaca tctaaaagcg ttgaaaataa aatggcacta
       61 gaagcagctc ctgggtcgat atgtccgatt gcacgctctc ctagatagga agctcgtcct
      121 tttttagcta ccaagacttt ggtgtgttct tttgcctggt caatgatttc ttttgttaaa
      181 ttccctgcct tcaatgcctc tgtgactggc agccaaacat ctaacatcgt tttatcgtca
      241 gcttctgcct ttcctcggct ttgaataccc gctgttccct gctcgatcac ttcgcctaat
      301 ttttcttgag aatcaataga atcgacctct tttgtcgctt tcatcatgtt catgaatgca
      361 gatccgtata acggaccaga agccccaccg actttcgata tcatcgccat agagaatact
      421 ttgaatgtat cgctgattgt ttcaggatga tcggcttgaa aagcttcttc ataagctgaa
      481 acccctcttc ccatgttatt tccatggtct ccatcgccaa tcggggtatc tagatcactg
      541 agatattgtt tgttctgatt gattgcctct gcaaattgcg tgagccattc ttggatttct
      601 tgaacggtta gtttcatatt atcacccttt tatcttgaga ttttttacca tgaaatcgtc
      661 tgtacattgc tttctaaaga atctttccat tgtgtctccg tcaagtcgat cagtgttaga
      721 gaaagacctt gcatatctag tgaggtcata aaattaccga cttttcggaa aactacattg
      781 acgcctcttt cttccaacag agctaaaaca tcattcatga acacgaactg ttccatcaaa
      841 ggcgtcccgc ccattccgtt gactagtaca cctgcttctt ttggtaaatt cgagtaatca
      901 tctaaaatct tagtaacaag ttcctttgcc agtactttag aaggctgcat cttttctcga
      961 cgatagcctg gctcaccgtg gataccaaca ccatactcga tctcatcttc tcctagttcg
     1021 aatcctggtt tccctacttc tggtacagtt gctgctcgaa gcgctagacc gatcgtctta
     1081 gttgcctgta cgaccttttc tcccagttct ttcaactcag ctagggaagc accgtttctt
     1141 gctgcatcgc ccacgatttt gtgtacaagg acagtacctg caactccgcg ttttccagca
     1201 gtatacgtac tattttcaac ggcgatatca tcatctacga tcacactttc tacttcaata
     1261 tcgtccatag cagctaattc ctttgccata tcgaagttca atgcatcccc tgtataattc
     1321 ttaacgatca gcaaaactcc ttttccacta tcggcttcct taatagccgt ctgaatctga
     1381 tctggagttg gagaagtaaa cacatcacca agcaccgctg cacttaacat cccttcccct
     1441 acaaacccgg catgggatgg ttcatgtccg cttcctccac cagaaaccaa accaacttgt
     1501 tccgctttct gattcttggc tacaacacgg gaagattcta cacgatgaac aagttctgga
     1561 tagcttttta ctaatccttc cagcatttct tcgacaatat tgcttggatc attcatgatt
     1621 tttttcaatt tattcccatc ctttctttcc ggcattttgt gcttctgtta agatttgctg
     1681 agtatcatct gttataccgg cagtgatggc tgctgcaaaa gctccttcca ctaaaggcgc
     1741 atccaccaga tgataacgtt gctgctgctc ttcttccaac atgtcttttg ccagttccga
     1801 gttcaatacc gcgctaccga tatccgcaaa aacaaaataa ctagctgcat cgcttgattc
     1861 attgactgct tctacgattt tcatcgggtc tgatccgatc tcgccattta ttccgccgag
     1921 agaaaaaatt tgcacctctt cggatttttg catctgctca atcatttctt taataccatc
     1981 tgttactttt tgactatgag aaataagcaa aatacttttt ttcacaagaa tcttcctttc
     2041 ttttacatag ttgctaacga ttggtttcgc tttcattaat gaacaattca agtatataat
     2101 aaatttctaa ttttgggaaa atatgtgtag tgcttcttga agtttgttat actttaatta
     2161 aaagagagga gtgatcgaat gattacaaca acaacgaaca gtgtagaggg aaaagccgta
     2221 gtagcttata aagggatcgt ttttggtgag gtcattactg ggatccatgc atttaaagac
     2281 ttggaggcgg ggttgcgaaa tatctttggc ggccgctcaa aaagctatga aaacgaacta
     2341 atgggtgcaa gagaagaagc acttgccgaa atggccgaac gtgcaaaagc attaggagct
     2401 gatgcgatca ttggcgtaaa aatggactat gaagtattag gcagcgacaa tggcatgctg
     2461 atggtcacat gtagtggaac agctgtctcc acgagataag taggggacat ctgttttaat
     2521 aactaaagag agatgggaca tgtagtggca ctcaagaatt agatttttca gtctaacttc
     2581 gaggtactct accttcccat cctctctttt ttatttcttt ttgcggatga ttccgtaagc
     2641 tgctgcgact aacacacccg cccctgctaa ggaataactg acagaagctg ttttttcatt
     2701 tgtttttggc aaagtctgac ttgttgattt ggatggctct gtcgtttgct gaactgtttc
     2761 tgtcgtgctt ccagaggtca ctgatttttc tcctgccgaa tgcaaaatat cttttattcg
     2821 ttggaaacta gctgctaagt cagctttttt tgcttcaaaa tcattagcaa ctgtttgtgc
     2881 ttcgctgatc tttccgtgga ttgcttgact ggccgctgtg atatccgctt gagtttgact
     2941 tagctttcca gaagctgttt gagcaacctg atttaattgc tgattgaatt cttttgcttg
     3001 ttggatcttc ccgtcaagat ctgtttggac agcttccgct tttgctttcg cttcggcaag
     3061 ctttttctca agttgtgcac ggtcatttcc cactttattt ttaagatcag ctaaatcttg
     3121 atcgattgct gcttggtctt ctttcaattt gttttttgca gcttctaatg cttcttcgag
     3181 ttcttttctt ttattttcca agtcttgcaa atgatcgatt tggtcagaag aggtagaact
     3241 atttattgat gtatcttctg aagatgaaat cgtttctcct gaattatctg tcggtacatt
     3301 ggaagtcatt tctgtttccg aggcaccgtt ttcagcacca gaagagctta tggttgttga
     3361 aggttctgtt tgagcaggtt cagaagtttc cgcaaaagct gtctgtccca ataagaaaat
     3421 actggaaaca gcaattggcc agattaacgg cttcattctt tttttcatca cttttcccat
     3481 ccttactact ttttaactaa tttcttatta taagcaaaaa tgtttggaag aaccataaac
     3541 acaacaggct gtttgtctaa aaaacggtgc atcttttatt tttttgtacg ttccgggctt
     3601 ttccatgtcc cgcttccata acctaaaatc gttttgactg ctggaatgaa agtcgtcacg
     3661 atcgttatcg cgttcactat ccagaacaaa agcatatata gtggtgcgaa aagaaggtat
     3721 ttcaattttc ttcgtcgatc atctacaatc agcgaagcta gcaactggaa aaatcctgcg
     3781 accatttcaa agcagatgaa cacaaaactg aatgtaaaag taatataaat ctgttcgtag
     3841 tttccttgat atacataatg cccgattaat ccagcaaaaa gaactacgga aatacaaaag
     3901 aatattgacc agacaatact caatgtttga tcaatgaaga tgatcgttct tccaatatgt
     3961 ttaaaaggat ggagcatcac ttttttgaaa ttcgtcagcc agacttctgt tccacctttt
     4021 gcccaacgtt ttctgtgtcg atatagcatc ttcaacgtca caggtacttc catgaaaaag
     4081 ataatctcag gagcaaaaac agataaccag tcatttaact gatgatccca agcaatactg
     4141 atgtcttctg tcgctcgatc ttgtctgaat ccgcccacat cgatcaaggc ttcttttcga
     4201 tacatcgtat ttgctccact gtacgcataa agaccaccga aaacagctga ctgtgttcgt
     4261 ttaatgatgc ccacgatact tgagaattca accgtttgag attttgcaat caatttggta
     4321 cgattttgga catccatatt tgcagtgacc gcagcaatat gtcttgcacc agggcgaatg
     4381 aaataattca catacctaat cagtgcatct ggctccggta ccgtgtctgc atcattgctt
     4441 aaaatcaatt tcccttttgc aaaggcaagt ccgatattaa acgcgtgggc ttttccttta
     4501 tttttttcga tccgaaccac acgaagatta gcgtattttt tcatcagtct agctaatatt
     4561 tctggtgttt ggtccgttga accatcgtct gtcactaata cctcatagtt gtgataattc
     4621 aatttcgtca tcaaatactc gattgtatat tcgatcacaa tttcttcatt atgggctggc
     4681 accatgatcg tgatgaacgg ttcgacactc aagggaacat ctacccattc tttttgctta
     4741 tgtttgtata aaaacacata acaccagaca ccaataaacc atacaaatcc gcctaaaatc
     4801 ggataagaaa cgagaaaaaa atacataata gacaaacaag tatctaagaa taaattacct
     4861 gtatgggtga ttgagatcat ttcagttcca ccccattttc tttatacaaa tctgcaatga
     4921 atgtcgtatc tagatttttc tcttcggaga cagaataaaa acggaccgtt tctctctctt
     4981 cttttgttcc aaaacgttcc gtatacactt cttcaagtaa ttcttgtctt tttttcaatt
     5041 tttcatcttc atattcaaaa gatttattta cttttttgta tagatttcga ttgttccacc
     5101 tagtcaatac aaatgaggta atcaggaaac tgaaaaaaat caatacaaaa aagccgatta
     5161 agaaatacag cattttcttt tctgataaaa aagcgtacaa ggaaaaatcc ttggctcttt
     5221 ctggtctcgt taatgggaaa aagacccata taaaaggaag aacaacgatc atccatccta
     5281 aaagagccac taacgtttgc caaatcttta accagtaatt accttttgaa aaatacttat
     5341 ctttcaccaa aattgatgca acttcttctc ttgttacttt tttcatatcc tcacctcacg
     5401 tttttttgtt acgacgtagg agtttaccat acatttcatt tcttttcaca taaagtgttc
     5461 ctaaattttt cctaagaaaa agaacaaaac atttctcatc agcaaatgaa aaatattttg
     5521 ttctttttat cagttgttct ttttattttt tatctcttaa ttatgttgct ctttccaata
     5581 cgacaatgct tttcattcct ctagatatcg ccgtgtacat ttgtctgcgt cttctttgct
     5641 catctccatc gttttcaaat ggatataaga ttacatgatc aaattccagt ccttttgcta
     5701 gactcaaagg aatgatttgg cagttttcta atccatatga atttttttta atcgattctt
     5761 gtagcgtttg ggtttcctct tctgtttggg tgataactgc cgctttttct ccttttagag
     5821 aaaccaaaat ctcagctagt attttcaaca attcttcaga ggatcgaaaa gagcggtatt
     5881 cgggttcttt tccttgcggt cggatcgata cgatgtcgat cttctcttga tccacagcat
     5941 aggttttgaa aagctctgtg attgctccgc tagaacggta actatttcta agatcatacc
     6001 gatggatcgg cagatggtag tcgtcgaaac aacgcataat atcagcaaaa gtagtggaag
     6061 aattaaagat tgcctgattc tcgtcaccta ctaaagtaaa gtgagttttt ggaaataatt
     6121 cgatcaatag acctaattgt gccagggtat aatcttgtac ttcatcaatc aatagatagc
     6181 gaaatgctgg tacatttacc ttttcaacaa gtaaatgacg aatagctaat ataatgactg
     6241 cttcatcaac agtacgtgtg ggttgccaag cataagctga gccatatcgt ttttcataaa
     6301 ttctttcaaa caactgatgc tcatccaccc atgccatttc ttcgatttgt ctggttattt
     6361 ttcgatattt tttttgtaaa agtttccttg cataagctac aatactttgt tccgaatcat
     6421 cagaaatcaa tttaccgaat aattccaact gcctatcttc tgtcaacgag agtacctgat
     6481 tctgcacagc aggacttttt gcttgtttca aaagatgatt cttccattcg ctcatcagtg
     6541 cctttttcgt tgcttgaagc ctatcgatca atttaggatg agcaggaact ttctcatata
     6601 ttttttcgat cgttttttta gaaaggactg tttttccatt tttagtaagt ccacggataa
     6661 aattcggatg atctaaaaac aaaggatctg attgttttag attatcgata aactttttgc
     6721 tacgcaaacg ttctgtctgc tccgatacat tttctcccgt gatacgtttg aaataagcct
     6781 cttcaccttc tatttcctct gctgaaagct gtgaaaccag ctgtatgatg gttagattca
     6841 gtggatttct ttcacctaat gatggtagga cattcgaaat atagtcgata aaccgatgat
     6901 taggtgatag aatcagcaag tcatcggatg tcatcgtatc tcgatataaa tagagcagat
     6961 acgcaatacg ctgcatgata gcagaggttt taccacttcc tgctacgcca tttaccaaga
     7021 tattttgact tttcacatcc cgaatgattg tgttttgttc cgattggatc gtagcagtga
     7081 tagccttcat ttcattggtc tcatcttggc ctaagacttc taataatacg tcatcttgaa
     7141 tagctacaga cgtatcaaaa aacttgacca aacgatctct ttccaaaaga aattgtcgtc
     7201 tttctttaat aaccgtatcg attttatttt gacgaaccgt ataagaagat ggaccaatca
     7261 tgttattgta aaaaagttcg gcaattggtg aacgccaatc ataaacaaga ttttcatctg
     7321 catcatctgt gaaatttgct gtaccgatat aaaaggattc ttttggctca ttatccagaa
     7381 agtctacaac gacttttcca aagtagggac ttttcaataa acgttcgatc tttgctagct
     7441 gattttctgc gtttttctgt ttgatattca tctgatcgat ttctctattt ttcatttcaa
     7501 tcatcgaaaa agtatccagg ttatctaagt aactgtcaaa attcaatcga agctcgccag
     7561 ccatttcttt caacgactgg tttccttcta tttttgccgt atccatcgat tcccgcagtt
     7621 cgtttttttt atcaattagc ttttgataca cgttcttcag atatgcttct tctaactgtt
     7681 tttgtgtgtt gaccatacac attctcctct ttttttaaag tggtggaacc gattagttta
     7741 cctcttttaa gagtcgaatg caagcttttt aacgagtatc atttgttagg atatatcagt
     7801 tcttcaggtc ggacagtttg atataaagaa aatgcaccat caaggttttt tacgtggtag
     7861 ccagactgct tcaagattct ttccgctaga tagctacgta atccgctatg acagctgacg
     7921 atatattctt gttggctgtc taattcattt aatcggtccc gaagttcatt caaagggata
     7981 tgtttggctt ccttgaattt gcccttttcc aattcttctg ctgttcgcac atctaataaa
     8041 atttttcctt ttgctagttc tgtcggcaat tcatgccatt gtacggtttc actaagccct
     8101 tctgcaatgt tcattgctgc atatcctagc atgtttactg gatctttggc tgagccaaat
     8161 ggcggtgcat acgtcaattc taattccggt aaatcgaaga tcgtcaaatg ccctttgatt
     8221 gctgttgcta aaatatcgat ccgtttatcc acaccttttg ccccaacacc ttgtgcacca
     8281 taaatctcgc cagtctctgg atggaagatc aacttcagta aaatatctgt tgcttctgga
     8341 taatagcttg catgatcttt tcctgataca tgaatgactt caaaagacag ttcgttttct
     8401 ttggctgttc tttcacttaa accggtggat gcggcagtca ttccaaacgt tcgtataatt
     8461 gctgttccaa taccgccttg atttcttcga gaaattccgg aaatcgtgtc cgcaacttgt
     8521 ctaccttgac gattggctgg tgaagcaaga gaaataagtg catcttttcc agtgatttgc
     8581 tgttttacaa cgatagcatc ccccaccgca taaatatcag gaatattcgt ttgataacgt
     8641 tcgtctacta ggataccccc gcgtatgcct aattcgattc cagcggtcac tgctagctgg
     8701 ttatcaggac gaacaccaat ggataaaata actaaatcag cagggatggt acgcccatca
     8761 tccagtcgca atcgtttccc gtggtcttca aatccagcga cagcatgaga agtaatcact
     8821 tctactcctt gatgagacaa ttctttttct ataaaagctg ccatttcttc atccagtgtt
     8881 ggaagaatat gtggtgcttg ttcgatcacc atgacttcta aacctcttct ttttaggttt
     8941 tctgccattt ccaatccgat gaatcctgca ccaacgatca cggcacgctt tggctgtttt
     9001 tctaatgcat gcatcacttt atcgatatct ggtacatttc taatagaaaa aacattgtcg
     9061 gcttctgtta tccctggaat cgatggaaca actggttttg caccaggaga taaaaccaat
     9121 gcatcgtact gttcaatgtg tttttgaccc tcatgtacga cttctaccgt tttgttttcg
     9181 ggaaagatgg ctgtcacttc atgatttgga cgcacatcta aacaaaaacg agcggataat
     9241 gattctggcg tttggacaag aagattttcc cgttcactga tttctcccga aagataataa
     9301 ggcaagccgc aatttgcaaa agaaacatac ggtccttttt caaaaacaac gatttctgca
     9361 tcttccatta atcggcgaag ccgtgtagca gcagacattc cacctgctac acctccgaca
     9421 ataacgattt tcatcttatt tccctcctac tgttcgatca aaccattgat tcatgccacc
     9481 acgtacattc actacatcat aaccagattt ctttaattct ttagctgctt gtttactcct
     9541 catccctgat tgacaaatca catagacggt cttttctttg tctccatcat atctgtttat
     9601 actttgtaat ggaacatttt tagctccttt tatatgcccg ccccggtatt ctgcaggtgt
     9661 tctaacatca agtaacgctg gattttccaa aagcttttcc tttaattctg ggactgttat
     9721 cgattttatt gattgaaata gcaaattcat tttctgcacc tcatttacat ttttataaat
     9781 acctcatggg gtatattaaa caggagcttt attaatatgt caaccagaat gactcttcat
     9841 ttttttcact actttttata tttgcataaa ataccgataa ggggtattat ctaattataa
     9901 aaatagagga gaatgtgtta tggagattga taataaaaat atcctgaacc gtttgaaacg
     9961 tacagaggga caaattcgtg gtatccaaaa aatgatcgaa gacgaaaaag aatgtatgga
    10021 tgtcatcact caattaagcg ctgttcgttc tagtattgat cgcgtaatgg gcatgatcgt
    10081 tgcagataat ctgaaaaatt gctttgagaa acctgatagt aatccagaag aacaagcggc
    10141 taaactagaa caagcgatca agatgattat taaaaagtaa aggaatgatt tcaatgaaag
    10201 tcgttttcca tattgatgaa ttagaaaaat ggtcagaaac agggaaaaac gtaaaaaacc
    10261 tgataaaagc ttctccagaa acgacgattg tcgtatctgt aaatggcatc gcgattaccg
    10321 gttatctaga ctctgccaat gcagaattct tagatttgca aggagtcgtt tttcacgctt
    10381 gcgccaatgc tatgcgtgct aatcatattt cagaaagttc tttacctgaa caagtaatcg
    10441 ttgtaccagc aggtgtcctt gatttagttg aactgcaatc ccaaggttat gcttatatca
    10501 agccttagtc agtagaggtt gcgacagaag tgatcagctt caagaaattt cggcttattt
    10561 ttcgaagaag ctacttctgg aaaaccgtga atcaaaggtt gtgaaaacgc tgtcctgcat
    10621 caagtaataa gaacagccaa acaaaaatag cttctcatat ttttcgtttg gttgggctta
    10681 ttaccgcaga tgcaagcttt tgaacaccgt ttaaggaaga ggttgtgaaa tcagcggttt
    10741 gacctaagta ttagagaaaa aaacgggaaa atagctcctc atattttgcc gttttttgag
    10801 ctaataccga aggtcagctg attgaacacc gtttaaggaa gagattgtga aaaagtcgct
    10861 tagtttcgag tattaagaaa aattttgtga aaatggattt ctacattttt gcataaattt
    10921 ggcttaatac cgagaaactg gcttttgaat accgtttaag gaagaggttg taaaatcagc
    10981 ggtttgacct gagtattaga gaaacaaacg gaaaaatagc tgctcatatt ttgccgtttt
    11041 ttgagctaat accgaaggtc agctgattga acaccgttta ccaagaggtt gtgagcctac
    11101 catttaactc cgaatcacaa gaaataattt caaaaacaac ttctcctgtt tttggttcgg
    11161 ttggcttatt atcgagaagt agctactggg agtctattta tcaaaaaaag gaatgcgaca
    11221 taggtcacac ccctttttta ttttctttga aacatctttc ggtactcgac agcatacaag
    11281 acaaaagatt gtaaaagacc gtaagtgatg acggcaaaaa tgactctcac ccacagcgtt
    11341 ggtaattctg ggaaaagcag caaaaggatc atgccaacat agatgacagc agtcgctact
    11401 ttgccatacc acttcgctcc acttaatttg atatttttag atagcccgat taatccagct
    11461 acaaacataa agccttcttt tatcaagaat agaccaaaca acagccaaag ccacggtcga
    11521 taccatgcca tagacaaaat cagaaaaagt tgtgtcaatt tatctgcaaa cggatcaagc
    11581 accttcccta agtctgttac ctgattatat ctccgagcaa tgaccccgtc tagataatca
    11641 gacaaacctg agacaacaat gaccgctcct gctatataaa atgactgtct cagcacaaaa
    11701 taaagataaa tcggcagcaa aaaaatacgg aatatcgata aaagattcgg aatcgtttgt
    11761 atttctttac gccagtctgt gcttaatttc attttatcgc cctacctcct cagcactctt
    11821 ttctttttat tttagcttac acggggaata aaaccaatga tttcactgtt tttatttttc
    11881 tttacagaca ctgatattat gagctaattt gagataatca cttgctgttt tcatcgttta
    11941 ctcttctttc ttcctgtcgt ttgcgcattt cttttactag tactttatga gctttttttg
    12001 atcctcgctc taggtcacgc tgccgtttac gtgttttata atcgataaac agactgtcta
    12061 aatcgtaacc tgtcgggtac agatcttctg ctgaacgcac cagacgaaca cgctgacgag
    12121 gcacgtggat tatttttttg tctaaatata catcaatcgt atcttcacct atatcttcat
    12181 aaactaacgc ttctttttgg tattcattga caaatatccg atcacctttt gcaaagagct
    12241 gacgttcttt tttattctcc ttcctatttg taactgctgt cttaggaaga aattcttttt
    12301 tctgtgtccg ataggctttt tccgccaagt aacgctctgc ttgatggatc aatttcatcg
    12361 acatatccat tttatgagca atccacaaag cttggctttc tcctgtttct tccaacccgc
    12421 aactgatatt taggacgaag tgcttcccga tcgaaagcca tagcagccgg cacaaaatct
    12481 tcatgatctc cggcgaattt cttgatttct ccataatggg tcgtggcaat gatcaatgcc
    12541 ccttgctcat acatagattc catgattgcg atcgctagtg cagccccttc atttggctct
    12601 gttccactgc caatctcatc taaaagtacc aacgtattcc tttttatctt tttcaaaata
    12661 gcagcgatgt tttgcatatg accagaaaat gtactcaacg cattttctaa attttggtgg
    12721 tcaccgacat cgacgaaaat ctcatcaaag acagcaagct ctgtcccttc ttttgccgga
    12781 acttgcatac cgaacatcgc catcaaagtc aataaaccga ctgtcttcaa cacgactgtt
    12841 ttgcctccgg catttgctcc ggtgataatc aagcctcgat agtctttacc gatttcaaca
    12901 tccaatggta ccgcatgctc aggtaaaaat ggatgtctgc cttgcttgat aatgatatgt
    12961 tccgatttat tgattctagg tgtgcttcca ttgatttctc ggctaaattt tgcccgagca
    13021 aagatgatat ctaacaccgt gatcgtttcg atcaataaat cgatcacttc ttcgttttct
    13081 gcgatagcac cagtcaatgc cgccaggact tgatattctt cactgatttc ttcagctttt
    13141 aacaactgat agtgttcatt caatttagaa atcacagttg gttcaataaa aaccgtcgtt
    13201 cttttatttg attcatcgat aatcgttcca tctattttat ttttatagct ggctttgata
    13261 ggaatcgtat agtattcgcc tttttgaaca atcattgctt cttggatcat ttctttgttt
    13321 ttcggatgac gcaagaattt cagtaatttt gactggattt ctttttcgat tagttgtaat
    13381 tgtttgcgta ctttacgcaa attacgtgac gcgtcgtcac tgactttatt attttttatt
    13441 ttctggtcaa tcaactcttc tacatttatc aaatcaggaa gatgtttgct ataagcaaac
    13501 aacaagggtg tctggtattg attcttatca aaaaactttg tgatcatccg actgcttcta
    13561 agaaaatccg catattcgat caaatcggtt ggctgcagaa tcaacccttt tttgacttgt
    13621 tctgtcagtg catcgatcct cggcaacccc ataaatggaa catgctgact gctttctaag
    13681 atcaagcgtg cttctcttgt ttcttcttga cgatccaaga cagtttgtag gtttgtcgag
    13741 accgtcatat cgctgattcg ttttttgcta tagtttccaa ttgctcttgc ttggatttcc
    13801 tttttgatcc gatcaaattg taattgacta atcatttcgt tgtccatatt ctctcctttt
    13861 cttgaagaga tacctgtccc aaaataaata agggcctaga gataaataaa aggatagaac
    13921 acagcttaaa aaagtcatgt cctatcctta ttagaataca aagatattgt tttcctgaca
    13981 ggtaccgttt cataagcaca ccaaataaac tttgtttatt ggctattcga cttactgatt
    14041 agataccagc tacactcaca aaacataccc cattcttcta ggtcttattt attttccact
    14101 taactatagc aagacacatt ttggttgtca aactttagta tgttttatag atttacacca
    14161 ttaatgaata gacacctacc gcgataattg ctccgatcat tggacctgcg attggtaccc
    14221 atgaatatgc ccaatctgaa gttcctttat tagctattgg caataccgca tgtgctaatc
    14281 gaggaccaaa gtcccgagca gggttgattg catatcctgt tggccctcct aatgaaagac
    14341 cgatggctaa gatcaatcca cctacagcga atacgttcgt tccaggtgca aattcgtttt
    14401 gtccaaaagc tagcaaccca agaactaata caaatgtacc aattaattct gtgatcacat
    14461 ttgctggata attccgtata gcaggacctg ttgcaaacgt tcctaaaatc gcgctttcat
    14521 ctttcgttgc attccaatgt ggcaaataag aaagccaaac aagaatggcc cctgcaaaag
    14581 ctcctaaaac ttgcgcaatg atgaaaggaa cgacaagatt ccaactaatt gcccctgtca
    14641 tcgccatagc tagagagact gcaggattca aatgagctgg gcccatgaat ccagaaatat
    14701 agacagccat tgttacagcg agtccccaac caaatgcgat gacaatccag ccagaagcct
    14761 gtgctttact tttgtttaaa ttcacagccg cacacacacc atctccaagc aaaactagga
    14821 tcagtgtccc aataaactcc cccatgattt gagtcatatc actgttcatt tatttctccc
    14881 cctttagttc ccgcagatct gattctgcaa tcaatgcttc taaacgttta gtctgttgcg
    14941 ccttctcctc ttctgtccat tcaaaatatc cagcaattgc atcgatcaca ggttgcttga
    15001 tctcatcaag ctgatctcgt tcaaacaaca gatgatttgt acgacgaatg agataatcgc
    15061 ctggggccaa aaccatttct tcttctaaac cataacgtaa ccgagctgac tcagcgagac
    15121 tcaaaccagg ataaggtgcc atttcttttg ctaattcaaa gatacgtcgg gcattagtcc
    15181 cgtaaaaatc agcgatataa gtagcatctt cttcctctaa accggctgct actccttctt
    15241 ttgctaattc tgtcactgtt tcttctaatt tagttggatc gaagtttcca cctgaaatct
    15301 gatatttttt agagtcgatt tctttcgtct ctattccgta ttcttctttt aataattggc
    15361 gtatcaatcg caaagctcct tctgccatct tacggtaatc ggtgattttc ccaccagata
    15421 aagtcagcaa accatctggt tctctttcta aagaactacc tctggaaatc gtagaaggtg
    15481 ctttttcatc acggctgttt tccaaatggt tcaacacgtc ttctacttca gcacgagaaa
    15541 ctttgttttc cttatattca cttactgtat cgacaacttt attgaagctc ttgtctgaaa
    15601 tcgatccatt atctccacca ttgtaatcag aaccagaatt accaatcaac agtggacgaa
    15661 gtcctgccca gcttgcttcg atatcattca atgtgatatt tgcttctgga tagcgatgat
    15721 tgatcacatc caatagataa tctacatctt cttgtgtgac tttcggatcc gtaaaatctc
    15781 cttggtaatc cgtatctgtc gtaccaaagt aagtcttgtt ttctcttgga atagcaaaaa
    15841 ccatccgccc atcttgcttt cctgtatcga agtatgtggg ttgcggtaca ggcagttttt
    15901 tcgcatctac aactaaatgg atccctttag ttggacgcat tttaggagag actggacgcg
    15961 taaaattcaa gtttcgtact ttatctaccc aaggaccact cgtattgatc actaattttg
    16021 ctttgatttc gatcacttca tctgtcagca ggtcacgagc tttgacgcca acgatttgat
    16081 cgccatcata taaaaagcca accgctttca ttttacttac tagataagcc ccatcttcgg
    16141 cagccttttt gatattatca atcactaaac gggcatcatt gttgcggaaa tctagataga
    16201 cacccgcgcc ttttagccct tcttttttca aaaacggttc tctttccaat acttcttctg
    16261 gtgtcagcgt ataattctca tatttggttc ctgtcacatt tgccagtttg tcataaaggt
    16321 ccattgctac tttgaccgag aacatattga aggttgttgc tccttcgccc tcatagattg
    16381 gcaaaagcat tggatctggt tttgggatgt gtggggcaat actttgtacg actgcacgtt
    16441 caccaactgt gtcagctact acttccacat caaatgtctt cagataacga ataccgccat
    16501 gaacaagttt ggtcgagcga gaggaagtcc cttctgcaaa atcctgcatt tcgatcaatc
    16561 ctgttttgat tcctgatgct gctgactgga ctgccacacc ggcaccagtg attccgccac
    16621 cgatgatcaa cagatccaat tcttcttgct gcattttttg aatgctatct tgtcttgtct
    16681 tgtttgaaaa catatggatt tcctccttat tcaaatgctt gggtagcttt tactgctttt
    16741 ttccaaccgt tgtaaagttt ttctcggcgc tcttcctcca tttgaacttc aaatagcttg
    16801 ccagcttcat aaaattcgcg gatctcgtct gtatctttcc aataaccgac agctaatcct
    16861 gctaaaaatg ctgcccctag cgccgttgtt tccaagtttt ctgctcgttg gatcggtaca
    16921 ttcaagatat ctgtttggaa ttgcatcaga tattcattgt ttgctgcacc gccatctact
    16981 ttcaatacag gaatcttgat tccagtgtca tcttgcatcg tatcgatgat atctctcact
    17041 tgataagcaa tcgactgtaa agtagcttta atgatatctt cttttgtcgt accacgtgtc
    17101 aagccaaaca tagcccctcg tgctgcctga tcccaataag gagcacctag cccaacgaat
    17161 gcaggaacaa cataaacctc atcttcgctt gtagagcgtt tcgctgcgtc ttctgaatcg
    17221 ctagcttttt gcaacatttg aagtccatct ctcagccatt gaatcgaaga accagccaca
    17281 aaaatacttc cttctaaagc atagtaaacc tttccattta tgccgtaacc aattgtcgtc
    17341 aataaattat ttttggataa ttgcggtttt tcaccggtat tcatgacaat aaatgaacct
    17401 gtaccataag tattcttgac catgcctggt tcgaatgcca tttgtccgaa taatgcggct
    17461 tgctggtctc ctgccatccc tgaaattggt gcttcgcttc cataaaaatg ataaccttgc
    17521 gtataaccat aaacttctga gttagaagtg acttttggta acatcactcg aggaatattt
    17581 agtaaatcta aaatctcctg atcccaatct agctgatgga tattgaacaa catcgtccga
    17641 ctggcattcg agtaatcagt aacatgtgct tgtccatcgg tcagtttcca tactaaccaa
    17701 gaatcgatcg ttccaaacat caattcgcct ttttcagctc gttcttgcgc gccttctaca
    17761 tgatcaagaa tccagcgtat cttcgttgct gagaaatagg catcgatcac taaccctgtt
    17821 ttttcgtgga aaaattcttg atagccttca ttttttaagt tatctgcaat tccagctgac
    17881 tgtctggatt gccaaacaac tgcatgatag attggacgtc ctgtatcttt ttcccatatt
    17941 actgttgttt cacgctggtt cgttatgcca atcccagcaa tctgatttgg tttgatccct
    18001 gattcgatga acgctccggc aataactgac tgtacagaat tccagatttc atttgcatca
    18061 tgttccaccc aactttcttg cgggaaatat tgcgtgaact ctttttgaga actgccgatg
    18121 tgtcttcctt tcttgtcaaa gataattgct cgtgagctag ttgtaccttg gtcaatcgcc
    18181 atgatatacg ttgattctgt cattgtgatt ccctccatta tatgcaaacg ctttctttaa
    18241 ctactcttat catactactg ttttaaaaaa agaaactgtc aaaattttat tctttttttc
    18301 tttttttgac agttttttat tatgaagcta ttttttaatc aattcttttc ttttttcagc
    18361 gtctctattc ttcttttcaa tcgaataatg tcgtaaggtg acgcaaattc tgacagataa
    18421 tattcacact gttttttgtt tctctggcaa aatgtgatca ccaaatcata ttctttacct
    18481 tcttcataac ttccaatctc aataccgccg attcccctca gttctctgat cagatattgt
    18541 tgaaaagcaa tacgataaat cggcagactt tctaaatcga ttccaatcac tactggtttt
    18601 gcaatataaa aatcgatcat caaaagaaca ttggcatact ggatcatcag gtaactaagc
    18661 tcactatctt cagctctttt cctcggcaat tgctgcaccg ctgtttcctg taatttcgcc
    18721 agtaactgtg ttaaggaatg cccgagcatt ttctgctgct gttccaaaag ccgatcacgc
    18781 tcatagactt cgatctttcc aacaaagaaa aaccattcat tgttgatctg ggaaatttgg
    18841 tagcctactg ccttttcttc tttgattttc aaacgacgag gacgataatg ccataacatc
    18901 gtttcccgaa tgtaagtatc taaaacagcg gttggtaact ttttgctccg tgtcaaatca
    18961 tactgataaa atatttcttc gtctactatc gaaaaagaaa caaaaaagct gtaaaacatc
    19021 attgtttcgt atacattcag ttctgctgct gttcgactaa gatgcatcac gatgattgga
    19081 tcgattgctt gataaagccg gtccgactga tagagtaatt tcttttcttt caaagttgcg
    19141 tacgtacttt tttcattcaa tagtcttttt ttcgtaatcc cgagccagca agcaatctgt
    19201 gcttctgctg atgccgtaaa cgttgtttct aatacacggt ccaatcctag aatgaacggt
    19261 cttttttctg gtgtattttg caaaaaaagc ggtcgctgat cttccgggat atattggaat
    19321 agttcataat aaaaatatcg tatctgtagc tcttctccgt ataattgacc gtttttgatt
    19381 tgtaatccaa attcctctaa gagctggttc aattctttga tctttcgaaa aacagaagac
    19441 tcactgatat taaacgctgt cgctaatcga acgatggata cttgctgatg ttctaataaa
    19501 tagacgagca tcttaaactt caagctttcc tgcaataaaa acaatagaat tttttccaaa
    19561 cttacatctt cgtccaacac aagcagcgcc tgatactcat ttcgctgtac ttctactttt
    19621 ttttccatca ttcggccaat caattcaata tcttccaaat attgatcaaa cgaggctttt
    19681 gacagttgga catgctctct caaaccattg atagaggctg ttcccccttg cagaacaagg
    19741 tttcgcaaaa tcaggatctg taactgctct tttctttcta ataatgcttc aatcttcata
    19801 ggcagtattc gccacctttg accacaccat atctggcaca cggtattctg gctggaaaaa
    19861 tagctcatgt tcttctaact gttcaaacgt ccatccttct tctactgcaa ttgtcagttg
    19921 gtcaagaagg tggaacatct cttttttgct ttggagctgt gctccaagaa tctttttttc
    19981 agaatcaaat agaaatttga gtttaacttt gctttgattt attgctgtaa gcttgtagtc
    20041 tacgtatcct gtttcaattt tttggggata aaaaatgctc tcttcttctg tcaaacctac
    20101 gcttcctaag aaatagccaa accactgatt gccgactgga cgataggttc cctgatcctt
    20161 tgtctgtgag ccactaattg tcttgctgac atttcgtgct gtacggacag cgttatttac
    20221 tagagaaaca tacatttttt catttgttgg acgaaaagtt acttggatcg catcgccaat
    20281 cgcataaacg tctttttgag acgtttgcaa gtagtcatct acccagatcg ttccatcatc
    20341 attcaatgtt aattgttctt cccacatctg attgtcggga cgagaatgat tagccagcaa
    20401 aacaagatca tagttctcct ttcttttttc cgtctctaca atagcggttt cattttcggt
    20461 caaagacaca acttgttctt ctaaaaaaag tgaaagccct tgatttttca tttcctttac
    20521 taacggttct gtcatttcag gatctagata acgaaaaaga attgactttc ggctttcgta
    20581 aagatggatt tgtttttttc ttgatgccaa cccttcagct atttcgattc ctgcttgtcc
    20641 tgcaccaata attgcaattt tctttgcatt catgatcttt tgctgaagag ccgttacgtt
    20701 ttgtatcttt ttaactgggt gaataagcgt tgattctgca gaaatatttc gaaacttttg
    20761 atttgaacca gtcgctagaa tcaaacgatc aaaatccaat ttttttcctc ctgctaaaac
    20821 gacttttttt tctttcaatc ctattactgt cttttctgtg taaacatgga ttcgatagcg
    20881 gtcagtcagt tcttctttcg tgatccaaga aagttgtttt tcactggtaa cctttccttt
    20941 taatatcaaa ttgaacccgc tgggaatcca tcctaacttc gattgctttt caatcaaata
    21001 tatttcactt gttggcatca attggcgaag ataaatagcc gcatgaatcc ctgcaaacga
    21061 cccgccgaca attacaatgt tcatctgcat tcctctttct tataaggtgt tctactgcta
    21121 acttctcaat cagaaaacac agtattcata actcgctttc aaccttatga tacatagcga
    21181 tgcagcagaa tcaaccctct ccatcatacc gtgttctagg tctgcttctc aataatgtac
    21241 tagtggacct aattgaagag tatcatttct gaagagatgt ttcaaaaaat gtactcttat
    21301 aaaagaaaaa aactcgcctt ttacgtacct ctgtccaaat aggaaacaga aaagaacgaa
    21361 aagacgagtt ttagcgtgtg taatgtaata gttagaatag acacatcatt tatttttaat
    21421 tctttaatgc ttcaacaact gcttcgccta attgatgagc agattgagga ttttgccctg
    21481 taagaagccg cccatcaatt tgaaccactt ctgaaaaagc tgctccagac tgatagtttg
    21541 ctcctttttc tttcaaagca tcttctgcta agaatggtac ttcattcgtt gtaccatttg
    21601 cttcctcttc ttcattactg aacccagtca ctgtacgtcc agctaaaata gattttccag
    21661 actcatctgt aactggcaac aatcctacaa caccgtgaca aacagctgag accagccctt
    21721 catttcgata gatttgtgaa gcgactttcc caagatctat tgcttctgga aaatcccaca
    21781 ttgttccgtg gccaccagca taataaaccg ctgcataatc atttgcatcc acatcatcag
    21841 gacgtaaggt atttcccaag gcccgatttc tgaaatcttc atcttcataa taggcccaat
    21901 cgatttcatc catattcaaa acactttgcg gttctaaagg tacatatccg cctttaggac
    21961 tgacaaaatc tgcatcgatc ccatttttta ctaatacatc ataaaaatga gtcagttcac
    22021 ttaaccacaa acctgtagga cgctcgatct tttcgtactt ttctacattt gttaatacga
    22081 tcaatacttt cattttccca tcctctttct ataaaaattg cgttattgat aacgtgcttt
    22141 caagaaatta tataatgggc ttggcaaata aagctcttta tatgcttttt caaaaggttt
    22201 cgttacaaat tcatcctcac ggttttccaa taatttctct gcccagtcag gatcgacgat
    22261 catttgctgt ccaattgctg caagttctgc atatttcaat acctgctcta catcttcgcg
    22321 attgcggatc ccaccgacac caactaaagg gatctttcct tgaatcgtgt tatggaccac
    22381 ttcaagaatc gatttatcgt tgtatttatc agaacgagct attcgatcat acatatttaa
    22441 tgaaacatgc agataatcta gttttgactc acgtaatcgt tcaagaagcc agatcgtgtc
    22501 ttcaaaacgg atacctggtg tttcatattc ttctggtgag aaacgatacc ctacgatgaa
    22561 tggtttttta gcatattgtt caaccgctga gaaaaccgtt gttaataatt cttcaataaa
    22621 acgataacga ttttccaagc taccgcccca ttgatcctct cgtctattcg aatgcggaga
    22681 gaaaaattgt tggatcaaat acgtatttgc tccatgcaac tcgattccat caaatcctga
    22741 ttcaatcgct ctacgtgtgg ctttgccaaa tgcttggatt gtttcaacga tttcttcttc
    22801 actcattgct cgtggtgttt ccgcatcagg acgttttgct gcaactgcac ttgcagatac
    22861 aggctgttct ccagataaag ttgctcgact tgtcattcgt ccaccgtgga aaatctgaat
    22921 aatcgctttt gcgccttctc cttggattgc tttcgctagc tcacttaatc gaggaatcat
    22981 ttcatcatga gcgatgctga gttcacctgg ccagcctttt ccgatatctt ggacatttgc
    23041 agcaccagta ataacagcac caagaccttt agaacgttgt ttataataag tgatctcatc
    23101 ttcggtgatc actccattga aaaagctgag ttgtgtcgtc ataggcgaca gcatcaatcg
    23161 gttcttcaat tgaactcctg aaggtaaagt aattgattga tcaaattgtg acattgtcat
    23221 tcctcccata attcgctctg attaacctat cgagaatcat ctatcattaa accactcgat
    23281 tagttgtaca tgcaactaat ttgcttaaaa aattttattt tttttgtaac ttatctgttg
    23341 catcattcat tgtctgggct aattctttac ttgcttcatt tcccaaaact gctttgtatg
    23401 actgatgaag ttcttcccag ctaccatcga cttccttagc aaattggcgt ccttgttctg
    23461 taagataaac taatgacaag cgaccttcgc taactgtttt gacgtatcct ttatattcta
    23521 atttttcaac aaaacgagca atcgttgatg gggcggaata gagcatttgt gcaatatctt
    23581 tttgtggtat tccatctttt tcttttaata tcaataaaat aaaaccataa gttggtgcca
    23641 gacctgtcct tctaaacgct tcatcagcta atttattcaa catgcgatct agctttttca
    23701 cgctaaagaa aagacattca tctaacgctt tttcaattgg cttttccatt tcatcccctc
    23761 cattggcgta catatcatag tatgattttt attttttgtc aaaaaacacg gaataatgtc
    23821 cgcctcctct gtctagattt gaaaaaaaga agtagccatc ttcaaagaat ttcggcttgt
    23881 tttcgacaaa actccttctg gaacaccgtg aatcagaggt tgtgaaaaag tcgtttagtt
    23941 ttgagtatga agaaaaattt tgtgaaaatg gctttccaca tttttgcata aatttggctt
    24001 aataccgaaa aactggcttt tgaacaccgt ttatatcaga ggttgtgaaa aagccgtcct
    24061 gcatcaagta ataagaacag ccaaacaaaa atagttcctc atattttgtc gttttttgag
    24121 ctaatgccga tggtcagctg attgtacacc gtttattgag aggtcgtgag cctgccgttg
    24181 aactccgagt cacaaggagc aatttcaaaa aacagcttct catgttttat gactatggtg
    24241 acttgtgatc gaggagttgg caggagaata ctgtttattc gtaaagaagg ggctgtgaca
    24301 agacttttgt cacagtccct tatttccttt tattatagga tttcgccatt tgattggatg
    24361 acttgtctgt accaatcaaa tgattttttc tttaaccgtt tctttgtgcc attcccttcg
    24421 tcatcttgat caacatagat atatccataa cgttttgaca tttgtgaagt agaagcgctg
    24481 acgatatcaa tgcagcccca cgacgtataa ccaaataaat ctactccatc tttgatagct
    24541 tccttcatct gctcaatatg ctgcttcaaa tagtcaatgc ggtaatcgtc ttgaacggtt
    24601 ccatcttctt ctactttgtc tatagctccg agtccgtttt cagctatgaa cagtggtttt
    24661 tgatacctat catataattg attcaaagca attctcaaac ccttaggatc aatctgccag
    24721 ccccattcac ttgatggaag atacggattt ttaattcctc cagttattaa gtttccttgg
    24781 accccttccc aattttctgg atgagcactg actgcactag acatgtagta gctaaaagaa
    24841 acaaaatcaa cagggtaggc tgctaagatt tcttcatcac ctacttctat ttttaagttg
    24901 acaccttttt cttcaaacat tcgttgcgta tacgctggat aatatcctct tgcttgaaca
    24961 tcactaaaga acaaagaagt tctttgctgc tcaattgttt tttgaatatc atccggatca
    25021 caagaatacg gaacaagaag ctgatagctg atcatacaac cgacttgtga acctttgata
    25081 atttcatgac aagcttttgt agctaaagca cttgctataa actgatggtg tgcaccttgg
    25141 tatttcgctt gttccaaatg gggatggttt tcttcaatta ctcctacgct aacaaaaggg
    25201 tgatgtttta cacagttgat ctcattgaaa gtcatccaat attttacttt atttttatag
    25261 cgtttgaata ctgtttcagc gaaacgaacg taaaactgaa taagctttcg attaggccat
    25321 ccaccatatt ctgtaaccaa atataacggc atttcataat gggaaagaga aacgactggc
    25381 tcaatcccat attttagaca ttcgtcaaac acttgatcat aaaaaaataa tcccgcttca
    25441 ttgggtgttt cttcatcacc atgaggaaaa attcttgtcc atgcgataga catccgatag
    25501 catttaaaac ccatttcagc aaataaacgg atgtcttctt taaagtgatg atagaaatca
    25561 tttccgtgtc ttttaggata ataatacttg ctgttgggat cctgcgccgc ttttacttgc
    25621 tgatgcgtca tcatatgcca ttgatctgtc catttttctt taggtaaatc gctgtcgaat
    25681 gtatacacat cagacacaga taatcctttt tcatctacat cccatgcacc ttcacattga
    25741 ttggccgctg tcgctccgcc ccataaaaat ccttctggaa attttttcat atcgatcccc
    25801 ctaaacttgc tagttttctt gtttgattat ttttcttatg actagtaatg atatttttga
    25861 atctactact atttgtaaca ataaccattg tggtcggatc atatccctct ttgattaatt
    25921 cttgcaaatc tacttccatc aataaatcgc ctttacgtac tttttttcca tcagatactg
    25981 cactttgaaa gtatttgcca tttaaattca ctgtatcaat accgatatgg atcagtatct
    26041 ctgctccttc ttcactgact accccaattg catgtttcgt tggaaaaact gttgaaactt
    26101 ccccgtttac agaactgtag atttttccgt ccgttggaat gatcgcaaac ccttctccta
    26161 aagatccact agcaaatgtt ggatcgttta cttcagataa atcaattatt tcacctgctg
    26221 caggagtact taacactata tcctttgagg attcttcttc gatttcatcc ttgtagccga
    26281 aaagaaaagt tagcatacag gaactgatca tcgctaagaa ataactagca actagccaaa
    26341 caaatccttc accaatataa atcgggaaag acaaaatact tcttgtagca actgccaaag
    26401 caccggctcc tgcggcacca gctactccac caaatatagc tccacatata caagcaatgt
    26461 aaaatggtcg tttatattta agagtcacac cataaacagc aggttcagtg attccaaata
    26521 atgctgtgat aaatgcagat aaagataaac tttttacttt cttatttttc gttttcaaaa
    26581 ataccccaag tactgctcct gcttgcgcag ctacggcagt catacatgct ggacctagcg
    26641 tatcacgacc gtagaaagaa agattgttgg tcattactgg tacaagtccc caatgtaacc
    26701 caaaaatcac taacacttgc caaaatccgc cgataacagc accagataaa acagggctaa
    26761 agttataaac agctaaatat ccagctgcaa tcagctgact tgcataatct gcaattggac
    26821 ctacaactaa taaaataatt gggaccatca cgatgataca aatgaatggt gtcaataaat
    26881 ttcgaatact ttcgtgcaag cttttgcgaa tcttaggctc aatataagaa agaacccata
    26941 cagctaaaat tgctggaata accgtacttg tataccttgc tagaatcacg ggcatcccta
    27001 gaaatcgcaa ggttatgcta tcactatatg cactgacaat cgtaggataa acgagagctg
    27061 ctgcaataac catagcgatg aaacgatctg tattgaactt ttttgcagca gtatatgcca
    27121 aaaatatagg caagaaatag aaaaatgcat cagctgctgc attcaaaatg atataagttc
    27181 ctgattcagt agttaataaa ttcaaactcg tacataaggc gagtactcct ttgatcaaac
    27241 cacttcctgc caagacgcct aaagtcgggg caaaaacagc ggcgatcatg tctataaaag
    27301 agtttaaaat gccttttttc tcagttcctc tctttccact agatgcatca tcttctagtt
    27361 tcatttgttt ggataatacg tcatacactt catttactgc atttcctact acgacttgaa
    27421 acattcctcc agcttcgact acagtgatca caccttctag ttgctctacc ttctccttat
    27481 ctgccttctt attatctttt agggtaaagc gtaaccttgt tgcacaatgg taaacattgc
    27541 tgacattttc ttcgcctccg acaaatcgga caatatcttt cgctaattgt gaatagtcca
    27601 tttttacttc ccccttgtta attaatgccg tagcaatcct tcttacaaga taagtatagt
    27661 tcttagaaaa cggtttctcc attcaattag taccccttct aatagcgaac gaaactgtac
    27721 aatagtgtgt atggtttact tagccgagca aatcactcac tgcttgaaag aaaacaagta
    27781 tatcgtttct cttatagtca aaggagacaa aaaaaacacg cttgatcttc ctttgctgat
    27841 gtataagtgg tatctcaagc tgatactctg tgatttttgt ttctacttgg cttttgataa
    27901 gacagcacaa caaagtctcg gcatttaacg gaagcataac taggtcagaa ctaggagaga
    27961 ttagttgctg aatggaatct atctttttat ggatttttat ttgattttct tctttgtagt
    28021 aatgatcaag cagttttgtt ttcttttttt cttcaactat ggtcagcttt tcacgcaaaa
    28081 tctgataaat ctcccaagat tcaaactcat ctagaacact aggtagataa atcaaatcat
    28141 cccactcaaa aataagctct tgctcagtag tcaaaattgc atcatattcc gttattttgt
    28201 ttgattgatt tttgaaaaga tacactggtt ctatccggca ttctttgatc cacatgttca
    28261 tactttgttg aatctgtttt tttagtgtat tcaaaatact aattggctgg ttactaacaa
    28321 tcagtatctc cccttgtttt cgaaaaggat tcaacgcttc ggcaagatac aaaacaaaat
    28381 aagcgctttc agctaaattg ggacgtaatt gaaaatgtat tgggaagaaa cgccgaatta
    28441 aataaatttc taaaggataa cgggagatga tcttttgtac aaaatgattc atggtattat
    28501 gtccggcatc catcctcgtt ttcatttgtt tgatatgggt tagcaaaaat tctgtttcat
    28561 ggaacaataa cgaaacagga agatctaaaa aacgaataat cgtttgctca aatgctctta
    28621 gattcttctc tatttctttg tttttttcat cattaatcat caaataattt aactctaata
    28681 gtcgattttc aattgcttgt ttttcttgat tggaaaaaga atagggtagt tctgatgata
    28741 acttttttgt gagggtctct accatcggaa taaataatgt atacctgttt gttttttcta
    28801 aaagttcttc tcttcgaaga atggtcaaaa cgagataccg agaaaatcgt atgaagtcct
    28861 ctcctgaaac aatataatta tatgatataa gaacctcttt taatgtcttt tggacagtcg
    28921 gcatgatatt ggaaaaaatt gtactgattt gttgaggaaa ccttgcgtgt tggatcaccg
    28981 tttctgttcc aacaagagat aagaaaattc tttttgaatt ttcttcagca atgattttta
    29041 gtccttttgt cgacgaaact tccagttcta atttaggatt gcgctcgatc caacgcaaaa
    29101 tcgtttttat ttgtaatgat acggctgttt ttgaaagaaa gaaaatgtct gctatctttt
    29161 gcatactgac ataccctttt tgaaacaata agtacgtcac aatagttgaa gctcggaaat
    29221 ccatgctgga atagatttta tgtttcgtca cctcttgtat gatttgctgt ttagtttcag
    29281 attcaattga ttctaaaaaa taacctgaac gtttatttga ctggataatg attttcttct
    29341 cgtagatagc aagcatattt ttgatttcag tttggatcgt tttcttgttg gtacctaaag
    29401 cttcagctaa ttcttcgctt gttatccaat gattcttatt tcttaatact acaagaattt
    29461 ggagttgtcg tttatttaag tccatttgct tacacctcct ctttgttata aacatacagg
    29521 aaaaacctct caaatgacaa tagtcacttg cagaggttta aaaatcattt gaagaaagat
    29581 ctatattcaa ggtttttacc attagactgg ataatttgtt tataatattc aaaactatct
    29641 tttttcaatc tcctaaagct tccgctccca tcattttgtc tatccacata aataaagcca
    29701 tatcgcttcc tcatttcccc tgttcctgcc gatacgatat cgattggtcc ccaccataag
    29761 taaccaatga tttggcaacc atcttttatt gcctcagcaa tttcctgaag atgtattttt
    29821 agatactcac aacgttttgg atcgtggatt cgattcaatt catctggtgc ttcatctagt
    29881 ccaatgccat tttcaactat gaataatggt aattcataac ggtctgtcaa ttcattcatg
    29941 acataacgaa accctagagg atcaattggc caactccaag gttcgggaga tttttccttc
    30001 aaaaagggat tatcgaaacc atttgctccg ccagtatcta cgcgcatttc tgcttctttt
    30061 ttatagacag cgctacgata ataactaaat gcaatataat ctgccgtgtt agcttgcaag
    30121 cactgttcgt ctccatctaa cattactggt gcacagtctt cttccttcca tgtcctgtaa
    30181 atataagctg gataatgccc tcggcacatg acatcggaga aaaaccatga attgcgttta
    30241 aattgcagtg aaccaaatac attctctgga tcacagtcat atgcataagt cgctaatgca
    30301 gaaaagctac acataatacc catcttagca tttggatcga ttttctttaa taattgagta
    30361 gcacgggcgt tcgctagaaa catatgatga caggcttgat aaatcacttt ttttgttagt
    30421 gtagcaatgg gttcaagttt atctctagca gggaatgtaa ccaatccagc agctgcataa
    30481 ggcatacgaa aagcattatt gatctcatta aaggtcatcc aatatttcac tttcccttgg
    30541 tagcgttcaa agacggtctg cgcataaaat tcaaaaaagt cgattaattt tcgattttgc
    30601 caccccccat actctcctac caatgctaag ggggtttcat aatgactaag agtaattact
    30661 ggctcgatat catatcgatt taatgtattg attagtctgt cataaaatac gagaccagcc
    30721 tcatttggct tctgttcgtc tcctcttgga aatattcgtg cccatgagat gcttgttcga
    30781 aaagctttta aacctaactc cttcagtaaa cgaatatcct cttcaaatcg atgataaaaa
    30841 tcaatcgctt catgagaaag ataatggagt gattcgtcta aagcaatctc ccaaatcttt
    30901 ttttcttcat tccactgaat actaggatgc tggttcatga tcccgataag cgtatctgtc
    30961 acattaggta atttgccgtc ttccaaccat gcaccttcac attgattagc agctactgct
    31021 ccgccccata aaaaattttc tggaaatatt tcctgatcca taactatctc tcctcgctat
    31081 caacaatttc ttacttgaag tatagctcga ttcatcaaaa caagatattc taactatttc
    31141 ggcagaagag aagaaaaaaa ttgaatgcta ctcttcattt ttaatattta tatataacaa
    31201 atacataaga cgatccccga aagaaaacac tcgttaacca tctaagcaaa cgatttattt
    31261 tacttccaac acaaatgctt cataaggtcg taaatcaact ttgccgtctg gtaactgttt
    31321 cagaggataa tttgacacaa taacccttaa agcttcacgt ggaatagtga acgtctgctt
    31381 ttcactggac atattacaaa taacgagcca ttgctggtct tcatatatgc gagaataggc
    31441 aaagacatgc tcaggcgtct tttccactaa ttcatagtct ccccagacga tgatgtcatg
    31501 ttttctacgc aaatcgatca atttcttgta catataaaaa acagaatctt gatctgctaa
    31561 cgcttcttct gcattgattt ctttataatt tggattgact cgaagccatg gaattccagt
    31621 agtaaaccca gcatgttcac gggcgttcca ttgcataggc gtcctagcat tgtctcttcc
    31681 tttcgccttg attgattcca agatttcctc ttttgtaaat ccagaagaaa tcctttcgtt
    31741 atacatattg attgtctcaa tatcttttgc ttccgcgata tcatcgattg ggcaattcgt
    31801 catgcctaac tcttctcctt gatagatata aggggtgcct ttcatcatat ggagcaagat
    31861 agcaaacatc ttggcacttt cttttcgata cacatcgtca tttccccaac gagaaacaat
    31921 tcgcggaaga tcgtgattat tccaaaataa actattccat ccttcatcac ctaaagatgt
    31981 ttgccatttg gataatactt ttttcagttc agagatactc aagggtttca aatcccattt
    32041 gtctttgcct tcttgctgat ctaatcctat gtgttcgaat tggaagacca tggataattc
    32101 atttctttta ggattggaat aaagtttagc gatttcggta gttgctcccc atgtttcgcc
    32161 aacagtcatc agatttttgt caccaaaagt tgcttgattc atttcctgaa gatactcatg
    32221 cagtttaggt ccattacttg tgatttcttt atccggttct ttgccaatca tatcgatcac
    32281 gtccatacga aagcccccaa tacctttatc gatccagaaa ttcatcattt gataaatctc
    32341 ttggcgaacc tgtttatttt tccaattcaa atcaggttga cgcttgctat acaagtgcag
    32401 aaaatattgc cccgtttttt catccaactg ccaagcagaa ccactgaata ttgagcgcaa
    32461 tctattaggc tcttttccat tgaccggatc acgccaaata taatagtccc gataaggatt
    32521 ttctttattt ttacgggcct caatgaacca cggatgttca tcagaagtat gattcaccac
    32581 cagatccatg atgatacgga tatttctttt ctttgcttct tcaatcagtt cttccatttc
    32641 ttccatcgta ccgaattctg ccatgattgc ttgataatta ctgatatcat acccattgtc
    32701 atcattcgga gactcgtata ctggagaaag ccaaattgca tcaataccta aatacgccag
    32761 ataatccaac ctggaaataa tcccccgcaa atctccaata ccatcttgat ttgaatcttg
    32821 aaaacttctt ggatagattt gataaacaac tgaatggtgc caccattttt gttccatgat
    32881 tttcctccta taaatggatg tttctatttt ttgcttaatc atttatttta gtctctctca
    32941 ctaaaaattg taacgctttc aaatagctat tgcaccttgt tatcggtaac agaataaaac
    33001 aaaaaaacag ctgaggaaat tccctcaact gttttttgaa aggattgatt tatgcaggga
    33061 agaatgctga tttcacaact tctttataaa cggtgttcac tcagctgtcc cttggtatta
    33121 gctcaaaaaa cggcaaaata taagaaacta ttttttcgtt tttttctcta atactcaggc
    33181 cagaacgctg atttcacaac ctctttattt cacattcaat atccacatga atcccacaaa
    33241 tacaaagaac agaccataca tgattggaga tacttctttt cctcttttag ctgctaacat
    33301 ggtaattgga tagaagataa aacctaatgc aatcccatct gaaatactat aagtcaaagg
    33361 catgccgatc aagatcaaga atgaagggat cgcaatctct aagtttcccc attcgatttg
    33421 tcgcaaagat tgtgccatca atactcctac cataatcaat gctggtgcag ttacttgtga
    33481 agtaacaact gatagtaatg gagaaaagaa caagcctaac aagaagaaaa tccctgtagt
    33541 aatagctgtg atacctgaac gtcctccaac ggcgatacca gctgatgatt ctacaaatgc
    33601 accaacagga gaagtaccaa ataaggaacc cgcaagcata gctgttgaat cagaagctaa
    33661 agctttccct acacgaggca tcttgttgtc tttcatgaaa cctgcttggt ttgctaatcc
    33721 aactaaagtt cctgctgtat caaagaaagt cacaagcaag aatgtcagca ctacgaccca
    33781 catttgaaga gaattgatgt cccctacatg ttttaatgca actaaaaatg ttggtttcaa
    33841 acttggtgct gcggcaacaa tttcagaagg cattggaatc aaacctgtga ccagacctaa
    33901 aatcgttgta gctgccatcc cgatgaagat gccacctggt acacgccgaa caagcaagat
    33961 agcagttacg actaatccaa aaatcgtcaa ccaagtagaa ccaacgttga gtgatcctaa
    34021 tcctactaat gtagattcat tcgaaacgat gatcccacct tcgctcagac caaggaaagc
    34081 gataaataga ccgataccgc cagaaatcgc atatttcaaa tctgctggga tcgcatcaat
    34141 gatcatttcc cgcagcttga agattgtgat caaaataaaa atcaaagaag caacgaatac
    34201 gccggctaat gctgtttccc atggaatccc cattcctaaa caaacagaat aagcaaaaaa
    34261 agcattgatc ccaagagcag gtgccgttcc aattggataa cgggctaata cccccattaa
    34321 aacacagccg atcgcactgg ctaatgcagt cgcagtaaac actgctcctt catccattcc
    34381 agaagcacct aatacagttg gatttacaaa taagatataa gccattgaga taaatgttgt
    34441 aaatcctgcc agtacctcac gttttaccgt ggtgttcaat ttttctattt cgaagtagga
    34501 aagtattttt tccttcatct tccatccccc taaatccgaa cattataaat aaagtccgtt
    34561 aaaatttcga tttattaata aaacaacgtg ttttatcata tactaaaaca aaacataagt
    34621 aaacaaaaaa ttcggatttt aagcaaaatc cgaacgttcc atctgattaa atccctttat
    34681 ctcaaagttc atgaacattc actttggatt acaagaattt ctttattgtg ttaataaagt
    34741 ttcttcattc tagtctcaaa aatcaatagt gtgatttgat tttaccattt cgtttctgtt
    34801 cttctttgat gaattctttt gtatcgacag gattcagatt atttagtccg ccaaaacctg
    34861 tatcgaccat ttttccccag ccttttgtct tcttttttcc tgatttgaga ttctttgctc
    34921 gaagcttctc actatgtttt gctcgccgat acttcaaata accttctaat cttcccatta
    34981 gatccactgt ttttcctcct ttttattcaa tcagacgact cagcttttcc tataacaaaa
    35041 taattgcctt cagggtcaga aaaattgaaa gtcaagatgc cattgttatc tgtgatttct
    35101 cctggttctt ccatgttctc gtagatagtt tcaaattcat ccgtaaaaaa tactaaagaa
    35161 ggcggtggtc ctaatacctc tggtgaaaac ttctgcacaa atacttttgg gaatacgcct
    35221 aattctaatt cttttgagat gctgagtaca atactcttaa attcttctgg caattcgatt
    35281 gtttcagaaa tttctgcacc aattttttct acaaagaatc ggcaaatcat ctctacgtca
    35341 ttgacataaa gcatcacacg tgttttttgt atcatcattt gacccttctt tctatttgat
    35401 tttctttcct gtctataaac tgattccatt atatcacgaa agcgcaaaca ccttgtgttt
    35461 gatactattc aagaaaaata aagcaatagt ttctaggatt gctttcctcc acaaactttt
    35521 tttacaaaaa aaaaacggca atgaatgccg ctcttcttat ttcgattctt ttataattct
    35581 gcttctgatt catctttggt tagtgtgtgt ctaacactag ttacgccaaa tgtttgatcg
    35641 attttttcct tcaacgcttc gattgcctgt gcgccacgtg ccgcttgttc agcattgatg
    35701 gattcaatga ccagcaccgc tgcttgtgtt tcttccgtca gcatcgttct ttgggcttca
    35761 cgccagttga gacagcgaca gatcgctcct tgttcatcat agtagatgat ttcttccgga
    35821 agtgccggag catcggaatc tgcacctaaa ggcaggaatg attcgccacc ttgggctttt
    35881 cctaaatgca gatttcctgc gatcttttcg atatcttctc cgccgcaagg tacgccaaaa
    35941 gacaaggaaa tactattata gatatctaca agcggattga ttgggaaaaa ttcccgttct
    36001 tgatttgcac gtttcagtaa agcttcaata gaagaacgtg cacctttttt agtcttgaat
    36061 gtggtaaatg cctgacgcca ctgagcaatg acttcgtttt ggctgaatgt ttcttctgta
    36121 aggtaatttc ttgcttcttt tgctgcctca ttcaataatt gatgatacgt ttcttcactt
    36181 tcttttgtta cgtggttatc gataccattt acggataaga tttcgatggt tgcttcagga
    36241 aatacttccc agaaattggt atccactatt acttttttca tctgttcaca cctcttgatt
    36301 agaataattg cttgatgaat agatagtctg tttggggatc atctcccata taaaaaacat
    36361 gttcgctgta tttgataaat ccttttttac gataaaaagc gagcgcaaca tcgttgtgtt
    36421 cccaaacacc gagccaaatg gctgtttttt gcttttcttt tgctttttca atagctgtat
    36481 ctagtaaaaa tgtaccgata ccttgatgtt taaatttttt tcgtacatag attcgctcga
    36541 tttctaaaaa atgatcagcc atttcctcag attgactcgt tcctgtattt agtttcaggt
    36601 aacccgcagg ctcttgatcg atactcacta ggaaaaaatc ggtttcttta tcttttagct
    36661 cttctgtaag tttttctagt gcataagctt gtgtcaagta atcagctaaa tgctccggtg
    36721 aattatcttt tccaaatgta tctgtaaatg tttcgatact aatttgttgt agtaagtcta
    36781 catctgaagg cgtcattttt cgaatttcgt atttattcac ggcttcttcc tttcaataga
    36841 tccttttatt gccttttttg acaaaattcc aatcttcgct aacattcttg catactttat
    36901 ttaaaagata ttccaattgt tttgcttctt cgtcagaaag accatttaat gcgactgcat
    36961 tggagtagtt gttttctcga atgatgaaag gatagatttc tgctcctttt ttagtcggat
    37021 agagtttctt gattttttta ttttctttat cttccaaacg ttcgatcatc ccattggatt
    37081 ctaatttctt gattgctcgg gcagtcgttg tacgatctac tttgatcatt tctgctagtt
    37141 tttcttggat gattccagga ttttcgcaaa tacgtactaa ataaagatac tgtcctcttg
    37201 ttaaatcgac ttctttgaat tcgatattgc taatagaatc tagcgctcgg gcaatcattc
    37261 cgatgtctcg aaggatttca gccatttcat cccaccttta ttttgtttgt aagactagtt
    37321 cacctctttt tgttgcaaat gcaactattt tcaataaaaa aatcaagttc ttttttaata
    37381 actagtaaag tatattcttt tcttctttta cgaaaaagct caatcacaat agatctggtt
    37441 tttgttttct aaaataagta actgtttctt cgttgttcgc ttttctgata gctttggcaa
    37501 ctcttctata ctaaaaaatc ccatgttgga agtttcatta ttctcaataa acttggcctc
    37561 ttcaccgtgg atcgcacaag caaaaacaag tttataatac tgaaaaagct gtggaatatc
    37621 tttttgttta ttcgtatcaa aaactgctcg caactgagta gtttctactg ttaatcctgt
    37681 ttcttcatag acttctttac gcacattttc ttcaggagac aatcctattt cagcaaatcc
    37741 accaggaagt gaccattctt tcgtccgttt atcttcgatt agtaggacct tgccatcttt
    37801 tttgatatag gcacgaacat ctacttttgg tgttggatgt ccttctccaa tcgttgtgag
    37861 cgcttttatt tcttcgaaag tttcttttcc tatttcactg atcagttcca atgaaatcgt
    37921 ccggatctcc tcaaaacgct ctttatcaaa tacatctttt ccataatata gaccagcttg
    37981 agaaagtgcg agtagtcttt tgtattgagc caacttcttg ttcattctct tcccttcttt
    38041 tttagcaaat gtatgactat gtaatcaagt atagaagact ggtttaatta cggcaaataa
    38101 atataatgaa atctgcaata aataaaagaa tgttaaaaaa ctcgagaaca aaagacattc
    38161 gacttctctg gggctgtgaa taaatggcgt tcaaaagctt gcatctgcgg taataagccc
    38221 caccaaacga aaaatatgac gagctattct tgtctggctg ttcttattaa ttgaggcagg
    38281 acagcttttt cacaacctcc ccactaaacg gtgttctcct accaactcct cggtcacaag
    38341 tcacaatatt catcaaacat gagaagctgt ttttttgaaa ttgctccttg tgactcggag
    38401 ctgaacgaca ggctcacgac ctctcggtaa acagcgttca aaagccaatt tttcgatatt
    38461 aagccatttc tttgttactt attgtcattg atttcttttt ctaatttatc caatagtgga
    38521 gtgtaatcca cttgagtata gtctgttaca tcaaattcat atagtgttcc taactggaat
    38581 ttgtcatatt ttcggtcggc gatgatcttt ttgaatgctt ctttcgtaat atgattggtc
    38641 cctttcgttc gatcttccaa tacgtcacca tagtgataat gatccatgat atagctcaaa
    38701 tgacgatctg attcacgatc acgtttgtac cgacgttgcc ataacacttc aaagtctgct
    38761 gttaggcgaa tcgtgatcac ctgatatccg tatctatctg ctaattcttg gagtcgtgct
    38821 ttttgcttat cactaaaagg atactcggac acaatcactt tctttcctgc ttccatatac
    38881 aaatcaagtg ctttgtaata gaaaggataa actttcgtcc tttcttgttc cgcccgttct
    38941 tccaaattgt taaacccgat ggattctgca tagtattcct tgatttcatc gagcgtgatg
    39001 gcatacatat ctggaaatcg ttcccgtagt ttattcataa gatatgtttt tcctgtacca
    39061 ggactaccag ccagaagaat gaaatacttt ttcatctcat ttatttccta agttaattgg
    39121 actttccaag ttcataaaca gtccaatctt atgcttgaca atttctttta ctgcttcatt
    39181 tgctggaatc acattatggc gaagagactt gttgatttct gtttcactaa aggtttcttt
    39241 agctactttc gtccagttga ctaaaagctc cgttccaaca ttgaatttgc ggatcccgtt
    39301 attgatcaat tcaggataat cttcttcttt cacacctgtt cctccatgga taactagggg
    39361 gacatcaact actgcatcga tttctttcag caagggaatg tttacttctg tttttgattt
    39421 gaattgtcca tgattcgtac cgatagcaat agctaatgca tccacgcctg tagcttctac
    39481 aaatttcact gcgtcttccg gtcttgtata taccttgtca ttttcagcga catggattcc
    39541 ttcttctgta ccgccgattg ttccaagttc tccttctacg gaaacaccgt gcgcatgggc
    39601 atattctact actgcttttg tcttcaggat attttctttg aaaggcagat gggacccatc
    39661 atacatgaca gaagtatatc cgctgtcgat tgcttctttg atatcatcaa agtctcgggc
    39721 gtggtctaag tgcaagactg catcaaccat ttcttcttct gcaatagctg tcattacatt
    39781 gactaacaca tgcatgccga tatatttagc ggtatcgaca cttgtttgaa taatgatcgg
    39841 cgaacccatt tcttttgctg cgcctagcat agcaggaagc atttctaggt tatgcgtatt
    39901 aaaagctcca actgtaaaat tcaactcttc tgctgttttt gttacttctt tcaatgttgt
    39961 atacatcttt tattgccacc ttatcttttt atttgtttcc tttgatcgtt acttgttttg
    40021 caatttgtcg catctcatcc attttgccca tgtagtaatc gatcccttga tcatcaccag
    40081 cacgagcagc atctgcacgc ttctggttat agaggctcat cagtttttta tacccatctc
    40141 cgatcgtctg tttattttcc aaactctttt ctaaatattg gatggcttga tcgttcacat
    40201 acaattcaga aaatttaagt ccaacttgtt cataaagttt cgctaattta tgcttatctt
    40261 gggtagtgga aatctcttgt ttcaattgtg taatctctga ttgaatcttt tcggtcgctt
    40321 ctggcgatag ggctttttct tcttttgcca gaactttttt cggttctttt tcttttttct
    40381 taaaaaatcc aaacatcatt ttccctactt tcaattaaaa tgctttcaaa actgggctta
    40441 agatccaggc atataagagt gctgcggcta ctgtatctac atcggttgct gtagcattgt
    40501 tgaatcccat cgaattaaag atcgttacta gcaaagcggg caataatgta ataaagaaac
    40561 catgagcaat accgccaatg atcgctcctc ggcgtccgcc aactgcgttg ccaaatatcc
    40621 ctgctgtccc tccggcaaag aaattggtta gcataccagg taaaatcatc gctaagccga
    40681 acatgggcaa agtaaacatg gcaataatcg taccaatcgt tgtcgtaatg aaacctaaaa
    40741 tgacagcatt tgggctataa ggaaagaaaa ctggacaatc taaggcaggg atcgcatcag
    40801 gaactaattt catagctatc cctcgaaatg ccggcacgat ttcacctaac agtagacgta
    40861 caccagctag caatacatac acacccacta cgaattggat ggcttgtaaa aaggcaaaca
    40921 tgatatagtt ttgatctcct gataattcag aagcgaatgg ttcgcctgca aataaaacag
    40981 tgatgatata tagcgggacc atcacgacca tgacagacaa ataagtatct tgcagaaatt
    41041 cgaaatgtgt cggcaacttg atatcttcga tcgacttttt attttcgcct ttctcaccaa
    41101 aaagcttagc aacaccggct tcaaataagt acccgatcgt acaaaaatga cctaaagcaa
    41161 tatcatttga tccagtgatt ttacgaatga tcggttgcgc tactgccggc atagcaatgg
    41221 cgaaacaagc tccgataaaa ccaccgacca agatcaatac gatccctcgc agaccggcaa
    41281 aatagccaaa gactgtcgtc atcgttgcca tccataaaat tgcttgacca gttaaaaaaa
    41341 tgtacttcca ttttgtgaaa cgagccaaaa taatattgaa tacaaaaatg gctaagaacg
    41401 tcagtgcaat atctctacct aaacccaaat cattcattgc ttgaccattg atagattcaa
    41461 tagaagggat gatcccttgc atatgaaatc cttcagtaaa gattttcccg aaataagtta
    41521 aacttccaac gatgatgctc gaaccggcac tcaacacttg aaatcctagg agtgtcttta
    41581 acgtgccaga gatgacttgt cctgctgatt tcttctgcag tagtagaccc aacatagcaa
    41641 tcaatgcaat ggtgatcgat gcctgagtca aaatattttc gatgataaaa ttgataacgc
    41701 ccatgttttg atgtgcaccc caaaagttag actagaaatc taattaaaag gggtgctttt
    41761 tttgcggaaa tatacatttg tttttaagaa aaaagtagtt tcagactatt taaataacga
    41821 aggcggctac aaatatcttg cacataaata tcaaataaat cgtacactgg ttagacattg
    41881 ggtaaggatt tataactatc atggttggga aggcttggtt ggaggtggca aaagctacac
    41941 tacaaaattt aaacttgatg ttatagaata tatggaaaca aatggtcttt ctatccaaga
    42001 aactgctaaa aaatttaata tcggttcaaa tagaactcta agtaaatgga tagagcaata
    42061 tgaagaaggc ggtgcttctt cacttgagag ccaaaaaagg ggcagaaaaa ttagtatgaa
    42121 ttccaagcta aacattccta aaaaacttaa agatgagtct cttgaagaag aagttattcg
    42181 tttaagagca g
//
LOCUS       DAFLWC010000014        38511 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.014, whole genome shotgun sequence.
ACCESSION   DAFLWC010000014 DAFLWC010000000
VERSION     DAFLWC010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38511
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.014"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(96..614)
                     /locus_tag="L1V17_000716"
     CDS             complement(96..614)
                     /locus_tag="L1V17_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBN1235501.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(616..1233)
                     /locus_tag="L1V17_000717"
     CDS             complement(616..1233)
                     /locus_tag="L1V17_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBN1235502.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(1230..2084)
                     /locus_tag="L1V17_000718"
     CDS             complement(1230..2084)
                     /locus_tag="L1V17_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1235503.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(2081..2992)
                     /locus_tag="L1V17_000719"
     CDS             complement(2081..2992)
                     /locus_tag="L1V17_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1235504.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(3033..4367)
                     /locus_tag="L1V17_000720"
     CDS             complement(3033..4367)
                     /locus_tag="L1V17_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1235505.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            4575..5405
                     /locus_tag="L1V17_000721"
     CDS             4575..5405
                     /locus_tag="L1V17_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBN1235506.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(5649..5967)
                     /locus_tag="L1V17_000722"
                     /pseudo
     CDS             complement(5649..5967)
                     /locus_tag="L1V17_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6089..6283)
                     /locus_tag="L1V17_000723"
     CDS             complement(6089..6283)
                     /locus_tag="L1V17_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235507.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(6788..6973)
                     /locus_tag="L1V17_000724"
     CDS             complement(6788..6973)
                     /locus_tag="L1V17_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235508.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(7823..8164)
                     /locus_tag="L1V17_000725"
     CDS             complement(7823..8164)
                     /locus_tag="L1V17_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBN1235509.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(8164..8394)
                     /locus_tag="L1V17_000726"
     CDS             complement(8164..8394)
                     /locus_tag="L1V17_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBN1235510.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            8681..9019
                     /locus_tag="L1V17_000727"
     CDS             8681..9019
                     /locus_tag="L1V17_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235511.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(9224..9463)
                     /locus_tag="L1V17_000728"
     CDS             complement(9224..9463)
                     /locus_tag="L1V17_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBN1235512.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(9439..9786)
                     /locus_tag="L1V17_000729"
     CDS             complement(9439..9786)
                     /locus_tag="L1V17_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBN1235513.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(10518..11099)
                     /locus_tag="L1V17_000730"
     CDS             complement(10518..11099)
                     /locus_tag="L1V17_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1235514.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(11282..11908)
                     /locus_tag="L1V17_000731"
     CDS             complement(11282..11908)
                     /locus_tag="L1V17_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBN1235515.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(11930..13261)
                     /locus_tag="L1V17_000732"
     CDS             complement(11930..13261)
                     /locus_tag="L1V17_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HBN1235516.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(13416..13817)
                     /locus_tag="L1V17_000733"
     CDS             complement(13416..13817)
                     /locus_tag="L1V17_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBN1235517.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(13903..14109)
                     /locus_tag="L1V17_000734"
     CDS             complement(13903..14109)
                     /locus_tag="L1V17_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235518.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(14204..15706)
                     /locus_tag="L1V17_000735"
     CDS             complement(14204..15706)
                     /locus_tag="L1V17_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBN1235519.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(15724..16179)
                     /gene="argR"
                     /locus_tag="L1V17_000736"
     CDS             complement(15724..16179)
                     /gene="argR"
                     /locus_tag="L1V17_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBN1235520.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(16277..16894)
                     /locus_tag="L1V17_000737"
     CDS             complement(16277..16894)
                     /locus_tag="L1V17_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBN1235521.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            17115..18488
                     /locus_tag="L1V17_000738"
     CDS             17115..18488
                     /locus_tag="L1V17_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1235522.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            18563..19675
                     /locus_tag="L1V17_000739"
     CDS             18563..19675
                     /locus_tag="L1V17_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBN1235523.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(19747..21384)
                     /locus_tag="L1V17_000740"
     CDS             complement(19747..21384)
                     /locus_tag="L1V17_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HBN1235524.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(21552..22160)
                     /locus_tag="L1V17_000741"
     CDS             complement(21552..22160)
                     /locus_tag="L1V17_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBN1235525.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(22544..23695)
                     /gene="queG"
                     /locus_tag="L1V17_000742"
     CDS             complement(22544..23695)
                     /gene="queG"
                     /locus_tag="L1V17_000742"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBN1235526.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(23714..24466)
                     /locus_tag="L1V17_000743"
     CDS             complement(23714..24466)
                     /locus_tag="L1V17_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235527.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(24607..25557)
                     /locus_tag="L1V17_000744"
     CDS             complement(24607..25557)
                     /locus_tag="L1V17_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBN1235528.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(25558..26397)
                     /locus_tag="L1V17_000745"
     CDS             complement(25558..26397)
                     /locus_tag="L1V17_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBN1235529.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(26394..27140)
                     /locus_tag="L1V17_000746"
     CDS             complement(26394..27140)
                     /locus_tag="L1V17_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBN1235530.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            27378..28748
                     /locus_tag="L1V17_000747"
     CDS             27378..28748
                     /locus_tag="L1V17_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1235531.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(28803..29699)
                     /locus_tag="L1V17_000748"
     CDS             complement(28803..29699)
                     /locus_tag="L1V17_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBN1235532.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(29813..29983)
                     /locus_tag="L1V17_000749"
     CDS             complement(29813..29983)
                     /locus_tag="L1V17_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235533.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(29980..30657)
                     /locus_tag="L1V17_000750"
     CDS             complement(29980..30657)
                     /locus_tag="L1V17_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBN1235534.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(30748..31653)
                     /locus_tag="L1V17_000751"
     CDS             complement(30748..31653)
                     /locus_tag="L1V17_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBN1235535.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            31828..33252
                     /locus_tag="L1V17_000752"
     CDS             31828..33252
                     /locus_tag="L1V17_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1235536.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMED"
     gene            33298..34329
                     /locus_tag="L1V17_000753"
     CDS             33298..34329
                     /locus_tag="L1V17_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBN1235537.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            34336..35523
                     /locus_tag="L1V17_000754"
     CDS             34336..35523
                     /locus_tag="L1V17_000754"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HBN1235538.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            35679..37061
                     /locus_tag="L1V17_000755"
     CDS             35679..37061
                     /locus_tag="L1V17_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBN1235539.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            37188..37418
                     /locus_tag="L1V17_000756"
     CDS             37188..37418
                     /locus_tag="L1V17_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235540.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(37618..38286)
                     /locus_tag="L1V17_000757"
     CDS             complement(37618..38286)
                     /locus_tag="L1V17_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBN1235541.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
BASE COUNT        11192 a         7789 c         6897 g        12633 t
ORIGIN      
        1 taagacaaat gaataaacaa ctacgctttc ctcgaaacaa aaaaataaag cacaaatgcg
       61 catttacgca ctcatgcttt attcgtacaa ttaattcaga taacggcagc gcataggatg
      121 ccaataacac ttcctaaaat agctcctcct aaaatgtcag taggataatg taaaagtaaa
      181 aaaatcctcg aataagcgat caaacaagca aataaaaagg ctaatattcc tgcaactgga
      241 cttaattcga acaacgcagc tactgataaa aaggctagcg ctgtatgtcc tgaaggaaaa
      301 gaagaagtct tcggtttact tgtgtaaagg acaagccgac gatttttttc ataaggtctt
      361 ttccgtcttg tcgttttttt gataaaaagc aaaccaacaa aaaaatagat caaactgccg
      421 ataagaatgg ctagaccata ttctctagta tcaggtatca agactaaaac agcagcaagg
      481 agcaaccaaa taaaaccacc attagagata ttactgataa atttcaaaaa attgattttt
      541 cgactatccg ttttccgttg cttggcgaac ttgttgataa tactatcatc gattttagca
      601 atcaaacgca acatgttatt cctccttttt aagaaccttt tcttgcgtac gatggataaa
      661 aagcaggact tgaaaataaa acaagaaact gaaacctaat aaagcaaaat agattggtcc
      721 tgcaaaccag aatgcgacaa gaaggatcaa cgtgcctgcc aaatagaaaa gcgcgctttt
      781 gaaatcatta aaaaacaaga aaaatgcagt aatccaagaa gcttcttttt gttccagttg
      841 aagcaagatt ttgtaactaa agagaagcgc gcttaataga agcaaaaaca acgtagtata
      901 catcaatgta tagccaattc ccccacccca atagcggaaa atctgataat cgatcaatag
      961 aagaagaaaa taaacacttg ctaaactatc ttgctttcca taaagagaga agttctcacg
     1021 aaactttttc cagaatagtg aaccgagctt tttctcttca ttttttttgt aatgataaat
     1081 catatacaga actgttcgac ttgcagttcc taatgtgaaa acaggcaaga cgcacaggaa
     1141 ccatagtagc tgtaaatgga taagacgtgg aatccattca atgatttcta agaaataatc
     1201 attggctttt ttaccaatcg atcgattcat catccttttg aacctcctgt caaatccatc
     1261 ccttcaatga aataacgttg tgcaaaaaag aacagcaaaa tcgtcgggat caagacaagt
     1321 gttgctcctg ccatcagata attccattgt gtcgttgctt ggttctgaaa aacttgcaag
     1381 ccaatctgta acgtgtattt ttcttgatct tggatatata acagaggacc taagaaatca
     1441 ttccaagctg cgttgaagga attgatcgca atggtaatca aggcaggttt cgtcaatgga
     1501 agcatcaaat gactccaaat atacaaatga ttcgctccgt cgatttcagc agcttcgatc
     1561 aattcattat tgatcgataa gtaaaattga cgcatcagaa atatattgaa cgcattgccg
     1621 aagaacgatg gaacgatcag gggcaaataa gtacctaccc agccgatctt ggagaataat
     1681 acatattgag ggatcatcgt tacaaacccc gggatcatca tcgtagaaag aaccaaagca
     1741 aacatcagct ttttcccagg aaaatcaagc ttcgcaaatc cataagcaat aaaagaattt
     1801 gaaaggacat taccgatcac tactagcaca gtgatgaata atgtatttct tgcatagcgc
     1861 caaaaaggaa aggcggcaat cgtatccaga tagttttccc atacgatttt ttctgggaaa
     1921 aaggtcggag gataacgaac gatttcttcc attggtttca atgaagtaaa caccatccaa
     1981 agcaatggaa tgatcaaaat gattcctatt actgtcatga ggacataact tagtattttt
     2041 tttgtttgcc gattcacact ggtctttttg aaataatcca tcatttgccg tcacctccag
     2101 aataatagac ccacttaggt gcaagcttca aattgacaaa cgtcagaacc aacacgatca
     2161 gaaacaggat cattgacata gccatcgcat aacccatatc aaaagctacg aacgccttgt
     2221 tccacatatg cagattataa aaaagcaaag aatttgcagg tccgcctgtt ccatttttcg
     2281 tcatgacata agcttcttga aaaatttgga aagaaccgat cgtagaggtg atcacatcgt
     2341 aaaaaataat aggagtgatt aatggcaaag taatactttt gaactttccc caaacgcctg
     2401 ctccatcgat ttctgctgat tcatataaag atctaggaac attttgtaat gtagctaagt
     2461 aaagtagcat tgctcctcca gaactccata ttttcatcaa aatcaacgca ggtttcgtcc
     2521 attgtggatc aaacagccaa gctggtccag ggatatggaa ccagcccaga aatgtgttga
     2581 tcaatcctgc agatggagaa agcagctgca tccataagat gtagactgct actcctgata
     2641 agactgccgg taaatagaaa gctgtacgga atacactgat tcctttgatt ttttgattga
     2701 gtactgtggc taaaaacaca ctgaaaatcg tcgtcagcgg tacattgaag atgacgaaat
     2761 aaacggtgtt gtataacgat ttccaaaata aatcatcgtg aacgaacatt cttttgaaat
     2821 ttgctagacc aatgaaattc atcttggatg tcaaattata atcggtgaaa ctaccaataa
     2881 ctgaaaaaag cataggccct agcataaata ccaagaaccc gataataaaa ggcgagataa
     2941 ataaataggc ccatcttgct tcttttttct ttcggataga taaacgcttc aaattttctt
     3001 gcctcctctg tacctagaca gtcaaaaatg gattattgat tttgcttgac taagttttct
     3061 actgcttttt gtgcatctgc caatccttct tttggtgatt ttgttcctaa aagaatctgg
     3121 tcaatctgtt cattcactaa tgtcgtgtaa tccggagcat ctaaaggaac tggtgtgatc
     3181 accgtatttt taaagttttc gtccgccatt tgatagatca tttttccttt atccgttagg
     3241 ttgtcattat tcactaaatt ctcattggct gtcttgctcg ccatgatatc aaaacttttt
     3301 tcgccgaatt tttcttgtac ttctggagaa gaaagatatt tgatgaattc ataagaggcc
     3361 tcaggatctt ttgctccgta tggtacttcc aagacgaatc cgccacccca cgaccaatgg
     3421 cctgaacctt cttctttttc tgggagctgc atcacgccaa aatcaaaatc atccggtgca
     3481 ttttccatca aactagagta ataattgata ttttgggcac gcatggctac taatccggaa
     3541 ataaatggat cagatacacc agacccaaat tcggcttcta atttattgat cgtatttttc
     3601 ccataataat cttgccagtc ttggatccac tccaaggctt ccactttatt tttagtatca
     3661 atcttgactt tttcatcttt gtcaaaccaa ctagtcccgt tatctgcgtt tagcgcccat
     3721 acatcagccc ctaaattcca taatggataa aaaccgatgc gtgtaaattc ttttccttct
     3781 tttttatcta gtttacgtgc tgtttcttct aattcatccc aagttgtcgg tagatcttgt
     3841 tcactgattc cagcttcttt aaataacttt ttattataaa aaatgacttg tgtatctgta
     3901 ttgaatggga tcgcataagg atcaccttca tattctactg tatcccaaag ctgcggataa
     3961 aaatccttag aagtgtcttt ttctacatat ttggagagat tagttgcttg ctgtgcttct
     4021 gctctttggg caacggaatt tatgtcctgt acaataacat cgggtgcatt tccagctgtt
     4081 attgcagata aagatttagt ccagatgtca ccccatggct gatacttata atttacatgg
     4141 atctcgtttt gtgattgatt gaaatcctca atgatttctt cgatagcttc ttttcgtgca
     4201 ccggatcccc aaaaggacca gaaatcaata ttttttcttc catcacttgt tttttcagaa
     4261 gaatttgctg cacttgaact ggcatcgctt gcattacttg atccgcatcc tcctaataaa
     4321 aacaatgctg aacttgccag caaccctgta aacaataatt ttttcatatt ttacctccaa
     4381 attttaatgt aaccgatgcc ggttttaata taacgatatc attttgttct gaaaataaca
     4441 atttataagg tatgattcta aaaaaattat taatgatacc aatactttat ataattcgcg
     4501 agcgctttct ttgaattttt taatctttcg tagcagaatg agaatgtatt aaaaatagat
     4561 taggaggaat tttgatgttt agacaccaga aagaattgca gtttgaagca aaaccagatc
     4621 gtccgaatcc attaatcgcg aaatatctgc aggagctgat cggcggccaa tatggcgaga
     4681 tgagtgtagc tatgcagtac ctgttccaag gctggagctg ccgaggagaa gaaaaatata
     4741 aagatatgct gatggacatt gcaacagaag aaatcggcca cgtggaaatg ttggcgacaa
     4801 tggttgctcg tttattagag ggtgcgcctg ttgaagatca agaagcagcg atgcaaaaag
     4861 atccaacaat cggtgccatt atctctggaa tgaatccaca gcacgcgatc gtagctggct
     4921 taggacctcg tcctgctgac agcgtgggca atccatggag cggtgcctat atcattgcga
     4981 gtggcaactt gttagcagac tttagagcta atttaaatgc cgaatcacaa ggaagacttc
     5041 aagtagcacg tatttacgaa atgatcgatg atcgtggcgt aaaagatatg ctgtctgttc
     5101 tccttgcaag agatagctat catcaaaatc tatgggaatg tgcagtgaaa gaattagaag
     5161 aaaaagaagg ttcaatctta gtcccaagta ctttcccgcg tgacaaagaa cgaaaagaca
     5221 ttgcttatga cttctataac ttctcagagg gagaccaaag tagtgaaggt tcttgggcta
     5281 gtggcaaagc actggatggc gaaggcgaat atcaatggtt gaaagaacct aagatcgaag
     5341 gcgctgcacc aaaattagaa ccagtaacac caaaaatgta tgggacacct ccattcaaga
     5401 aataaatatc tacccgtaga aacacccgtt ttttgttcca cacgctttgt gagcaaaact
     5461 gactaaagtc attaatcata accacccttc aaaagggtgg ttttctctag agctataagc
     5521 tcaaatcacc ggccagcgcc taaagacgct ggctttcata ttttatgttc aagccatatt
     5581 gcctttgcca gttttgccca cctcttaaaa ggtttatgta ctactcctta gcccttaaaa
     5641 ggatcgtctt actctcgtac actcagctta tctaacgcac tatcatgttt ttcttgttct
     5701 tgaatgtact ttttgatggt cgcttcattt tgtcctactt ttgtcacata gtatccttcc
     5761 acccaaaagt gtcgataccc aaatttatat tttagatttg cacaatctct tgatgatctc
     5821 ctgaatattg gctcgatatt gattataaat tatttttctt ctatactttg gtgtgaatac
     5881 aatgtggtat ttacacatct actttgtacg ggctaaacta tttcccttta ttgctccacc
     5941 cgcatagcaa gtggttttgt atttcaatcg ctcggcgcgc tcaattaggt ctaaagacaa
     6001 taaatctaaa aacccgctgc ttcactgaca gaaacaacgg gttttcagaa aaaaatgaaa
     6061 tgaaaaagat ctcttacggc aatctatttt atttttttga ttttttataa atggaaaatg
     6121 cttcaagaag tccaagaaat aaagccgtat aaaaacaaga acctatgaaa tctttattta
     6181 ttagatattc aacagaaatc ccgataacac tagccaacaa tatatttatc agaagtgtaa
     6241 aataaggatg ctttttatag aatagaacta gtgttgtttt catagactct cctttcttca
     6301 tatttccaat taatcacaaa ttcacggcat tactagaaaa attaaagggg cgcagaagtg
     6361 gaaaaatact cttcgacttt ccctacaaac caggccatct tgtgtttaat aactatacca
     6421 aatctaaggt acctctaaat ctaaattcca tttgtggcgg tgacctccaa tttttaactc
     6481 ttctatctcc catccagtat acataacctt gatacttcga ccacttatat atcgaacaca
     6541 caaataccta tccattgcag gagtactacc taacttagtt gctacttgca tctaaataac
     6601 agctgaaaag ataggactta ctcttagtaa agtatctgaa ctattaattt ttaaactatc
     6661 atttttatcc tcaactacat gcacatctgt tgcaacttca ctttctgtct catccagata
     6721 aatgattaag gaatcgggaa ttgcaatatc ttcagctgac gctggaatag ttgagctaaa
     6781 ttagtcatca tatctttatt ataaaataac caacagcaaa aaatacaatg aaaaacaaac
     6841 ttggaactaa tgtatcatta ataaatgttg aaaaattcag caactcatta ctgtatgatt
     6901 ttagcagccc aaccaacata taccctataa aagctaataa gatggttagg aatcctttag
     6961 aatttttact cattcataga cacttcctta aataactttt attatagaag gtattgtaaa
     7021 taataatatt gacaaaaagt gactcaaaat aaaaaaaacc ttacattata ctggaatgaa
     7081 ctgtattgat agtgtaccta aaagctctac tgacataaga tcgtgtaatc ggtaaagtaa
     7141 ttttattaat tatacgggat gtaatcaatt agagaataaa ctaatcataa aaggtacttt
     7201 tacattcata attgtcgctt tgagattcta ctttggttca ctatctgacc caattgcaca
     7261 ttttcgatca ttacaagtat tggtgtcgtt agaacaacta aataaaaact agcggtagat
     7321 ttttcagaat ctatgctaat ttctgtatgg atgttccagt gatggcaaat ttctcttttc
     7381 attgtttttc ttgtcgcatg atatgccttt ttgtgttatt cagttaaact atagaaattc
     7441 tttcctagac agatcttgat cccaaatttt acgtttttga gcatcgatat agtttaaaat
     7501 gacattactc atatctaaag agtttagatt ttttaggact aaaactgtca gttgttcttt
     7561 ttcttctttc tgttaaagta ttgtcgcgac ttttcgtata cgttaagata tgtcgtgaaa
     7621 aaacaagttt tgtgacacaa aaaaacgaat gacttgagga aatcacctca atcattcgtt
     7681 taaaatgcta tatattcttt agtttaagat acggaaatta atgccatcga ccacactagt
     7741 agaatgaacg acatttactt ggcctttttt taatttcgtt atgtttagca tataaaaata
     7801 ttatagagtt tacttacaat gcttaaaaca tatactgtat aatctgatca attttagcca
     7861 tgtcttgcaa tggtaagttt tctatttttt tgagttttcg ttccttaaaa tcaagagatt
     7921 ttaattgtgt aataattact tgtcctttta tatctagctc ttcaggtaat gagtaacgtg
     7981 tcggtaaatt ctttatagtg gaagtaattg gacatatgac cgaaaacatt gttttacggt
     8041 taaattcata acgagagacg actagtcctg gtcgtctttt ttgaatttct tttcctacgg
     8101 agggatcaaa atcaatccat acaatatcac cttttttagg aatataaatt ctttcttctg
     8161 acactataaa atttctctcc cttcaggagt taaatcttcc cattcgtctt tctcataata
     8221 ctcggcctct tccccaccac taaatggatc ttcaattttt ggaactaacg taattgttcc
     8281 atcatcagaa tacacaacga tatattcttg gttttctgaa ggtttctttc cgttatcaga
     8341 aggtaaagtt accactacag aacttccttg taatctagat tttgtaacaa gcattatcat
     8401 cactccctta ataaaagtat actatataac actaagtaac gcaaaattcc cctttgtaaa
     8461 ctatctagaa aattgttttg tttaaagtat atcttattgg atataaatag aaataaattg
     8521 tagccagttc attttttctt taactaaaaa aataatccaa gaaacattga acctatggat
     8581 ccaaaagcta cccaaatact atagctaacc ccccgctacc ttcaattttg cagataaaac
     8641 gctttgggag aaaatttcaa agacaacagg ccatcctatc atgcccgatt ataaacaaaa
     8701 agctggctat tccttttgct ctgacaaatt tcaattggga aagttcacga aactagcagg
     8761 tgaagaagtt tcaactgttc ggatcaaaga atgcccgctt caaatagaaa cattggttca
     8821 acgaatttca actagacaag actttgctat tgtagaacgt gagatcgtag ctatttttgt
     8881 agaagaaggg attttacatg atccaactca tatcaatgtg gataaatggc aacctcttat
     8941 ctataaattc agagaatata caactgccaa ccagtcgtta actttgaatt ttagattcca
     9001 agaattcaaa gagtcataat gataaacatc gttaggtata aataaaaaag actcgcagca
     9061 cgagtaaaaa acaaatagaa gctatacatt agaaaggtcg actgtgaccc tatagatgca
     9121 gtatatgcag cttatgagca tttcttctgt tctctttgtt tttgggatct gtgctgaagt
     9181 ctttttcgtt ttttgccgct ctttctttga aaaatcgatt atgttatacc ttctccatta
     9241 ctaattcagg catctgctga gtaatgattt ttcgcgcaaa agaaatatct gttacccaag
     9301 gttcgatttg ttcttcagtc aagacaagcg gcattcggtc atggattggt gcgactgtgc
     9361 ggttaggttc agtagtcatt atgattgatt ctgccatttt ttcatcctga tggctacgat
     9421 aaaaaccgcc aatatacact attttttcct tatttgaaaa cataaatttg tctttttctt
     9481 cattccactc attgggaaaa cacaacgatt ttgcaaaaat ggttgatgaa aggtcttttt
     9541 ttcttctact gtctctgcac gggcattaat catcaattgt ccttttttaa atccggtaaa
     9601 tccccacttc atgatttccg gagtgaggat gttttcttcc tcttttctta acgtcacaac
     9661 aagatttgac ggaaaaactt ctccagctgc taattctgct gcctgcttcg gttgtttcgt
     9721 ctgggcttct cgataataat tctgaaggag ctctgactct agatcaaaaa aataacgacc
     9781 acacatccta atccctccca atcttttttt ctatcataca ctgcaacaag aagttcgcac
     9841 caacaaaacg ctttcaattt ttgtagaact aaaaaagttg tgacaagtga caaactctcc
     9901 agtgaatggt attctcctgc caactcctcg gtcacaagtc acaatattca acaaacatga
     9961 gaagctgctt tttgaaattg ttccttgtga ctcggagtga aacggcaggc ttacgacctc
    10021 tgggtaaacg gtgttcaaaa gccagtttct cggtattaag ccaaatttat gcaaaaatgt
    10081 agaaagctat tttcacaaaa tttttcttaa tactcgaaac taagcgactt tttcacaacc
    10141 tcttccttaa acggtgttca aaagcttgca tctgcggtaa taagcccaac caaacgaaaa
    10201 atatgagcag ctatttttat ttggctgttc ttattacttg atgcagggca gctttttcac
    10261 aacctctcca ctaaacggtg ttcaatcagc taaccttcgg tattagctca aaaaacggca
    10321 aaatatgagg aactattttg ccgtttgttt ctctaatact caggtcaaag cgctgatttc
    10381 acaacctcta atacacggtg ttccagaagt agcttcttcg aaaaataagc cgaaatttca
    10441 caaaaatttg agaagcaatt ttcgtaaatt ccttcttatt tcttgaagct gaccacttct
    10501 gtcacaacct ctaattatta aagaaccttt tgcgaagtta acaatctttc tttgatcaat
    10561 tgaaaattct gcctaagtag tgatagatcc tgtgtgactt tcaacaataa gatacttccc
    10621 tggatttcag caatcaacgc tttggcttga cggtctgctt cttcatcgga cagtttttct
    10681 tcagaaagtg ccaggatatt ttgtttcgta tacttgaccc attgattgac taattctagt
    10741 agcaacagac ggtattcttc atccactgta ctcaactcaa taatcaaatt acctacagga
    10801 cagccatgat aagtgatctg tgtctcatga tcagcgaaaa tccagtccaa catttcttct
    10861 aatgcttctt ctggctgttt tccagcattt aagatgtctt cgaacaattc tgtctgccat
    10921 acgtccatat gcgcatggat caccgctaga caaacttctt tttttgaaga aaagtaataa
    10981 taaaattgac cttttcctgt atcagaagct gctagaatat ctcggattga cgtttcatga
    11041 tagccttttt tataaataag atctttggtc gcttccaaga tcttttcctt tgttttcaat
    11101 gatattctcc tttttcattt ctcatagtcc tatattatac agtaaattca tcattttttc
    11161 ttcttaatcg tttaaaaaag actgtgccaa attatctgac acagccctca ctataaaact
    11221 gttctcatat agctagatgt tcattgattc aagaactgcg aggacaaaag caattcctat
    11281 cttatgatag ttgctctaat acttcctctg ttgtcatcac ttgatctgca ataaagccaa
    11341 agttcgtcaa cgctgcatcc attgcttctt ggccaggagc accaattgca tctgtcgcta
    11401 ccacaacatt gaatccactc tctaccaatt cacgcatatg ggaatcgcta cacaagtttc
    11461 cgttcattcc accaagaatt actgtgtcga ttccattttt tctcaattgg agcgccaaat
    11521 cattgctttc tggtccaaag attttatgag gagagctgat gatcgtattt tcatccaaat
    11581 aaggtttcaa ttcttcgata aaatcggctc ctgaaccttc ttccactgat tcatattgac
    11641 tttttctagc aaacatctgc tgctcaagca tcatatgttc tcctgcaccg ccaaattgcc
    11701 atttatggtc atgtgggtaa aaataatgag gagaaataaa gagtttgtat cctttttctt
    11761 ttgcttgttt taccatttca atcatatttt cgatcgtatt gtatttttct aagatatctt
    11821 ttgtcaaacc aaagccaccg cctgctggtt tcaagaactc gacttgcggg tcagtgagaa
    11881 ctactgctgt atttttatta ttgaacatgg tggattctcc attcgttatt tattttaata
    11941 catcatttag agcttcactc attgtcggat gagaatagat ttgatctctc aataacgtat
    12001 aaggaagttt tccattcata gctagcgaaa tcaagttgat gacttcatga gaatcttccg
    12061 catagatact tgcccctaga atcaagtcag tttcagggtc gactaaaact ttgaatacac
    12121 ctttaggatc ttctaatact tgtgctttag ggacaccgct tgtcatatac ttgaataatt
    12181 tgtaattgac gccttgtgct ttggcttgtt tttctgttaa acctacattg gataaagtcg
    12241 gagtgataaa tacactgtaa ggcacagctt tccggttatt cgttgttcgt ttattctcgc
    12301 ccttcaactg atccataatg attcgataat catctagaga gatataagtg aactgcaatc
    12361 cgcctttgac gtctccaatc gcccaaatgt tgtctgcatc tgtacgaagg tattcatcca
    12421 cagcgattgc tccgcgatct gttagtttaa catctgtatt ttctaatcca agtgatgctg
    12481 tacttggttt tcttccagtt gcagccaaaa cttttgacgc ttggattgtt acttcttggc
    12541 catcttctgt aaaggtgacg gcagctgttg attcttggtc tgctacttga tctacagata
    12601 cacctagatg gaattcgatt cccgcatttg tcatgtcttc taaaatcatt tgcgcgatat
    12661 cttcatcttc acgtggaaga aattcagaat gggcatcaag aacgacaact ttagatccgt
    12721 attcattgaa cattgatgca aattccaagc caatatatcc agccccgatg atcactaatt
    12781 tttccggtaa ttgttcctga tccatcgctt gcgtagaatc aatcaagtag cgacttgtat
    12841 tcaatccttt gattggtaaa atgattggtt cagaaccagt attgatgaaa atccgttcgc
    12901 cttcaacaat cactttttca ccattattcg tcacttcgat ttgatggtta gaaagaaaac
    12961 gtgctgtacc gtccatcact gtcccagttg cctcatcgct gatcatatga taatttttgg
    13021 cgcgaagcat gcccgtcaat ttttctttcc gagcaacagc ctctgtaaag tcgattcctc
    13081 tttctccatt gaaaatcaat gatttagaag gaatacagcc gatgttgata catgttccgc
    13141 catacatacg tgttgacttt tcaacgacta aaaccgattc accttttgaa gctaacgcct
    13201 tcgctaaagt cttaccgccc tttccaaaac cgatcacaat attttgatat ttttccatca
    13261 tttttccctc gcttcttttt tacctaccga ttggtacaaa aatatgataa ccgataattg
    13321 tctattctcc aaatcatctg ctttatttgt caaaaaaaac cagacaaaaa gcggtccttt
    13381 cacgttttta gtctggttcg atttccttta ttcttctaaa caatcgttac ttctacatcg
    13441 atatttcctc tagttgcttt ggagtaaggg cagaattcat gcgcatcttc tgcaattttt
    13501 tgggcttctt cttcgctgat gccatcgata tgcacttcta atactacacc gatctgatag
    13561 ccgccatcat ctaaattata aagagagaca cgtgctttta ctgtggactc tgctgtcatt
    13621 cctgcttctt tgatcatatg ttgtaccgcc ccattgaaac aagaagcata acctgctgca
    13681 aataattgtt ctggatttgt tccttctgca tggattcctg gaggagtgat tttcatatgc
    13741 atcgagccat ttggtgcctc gacttctcca ttgcgcccgc catggttgat cattgctgtt
    13801 tcgtatgctt ttttcattgt actgctcctt tcgattgacc atttgctact tggctataat
    13861 tatagtgtat gacaagtaag gcgctttcta caaaaattct gcttattcga ataccagaat
    13921 gccgtcttct actatttttc caaaaaacaa aaaaatacta ctcgtgaaca acagcgtcat
    13981 atttgttcca aaataaatag caatcttttc tacataatct tttatatgat tgattttaag
    14041 atacatatat accagaaagt tgaccccata aaccaatact gttaaaaaaa taaccatatt
    14101 cgttaccatt ttttcctcct tttgctggtc tccctaccag cactcgattt aaccatacca
    14161 ctttttttgc cgtccaagca actagccttt caaaaagact ggtttattct gctgttaatg
    14221 attcaagatc agaaaaatgt ccgaataatt ttgctaattt tactaacgcc aacttgttct
    14281 ttccgaattc atcattttct atctgtaata ctagtaacgg ctcatgtaag cttaaacgga
    14341 tcaaaaacca gccgtttccg tatggctctt ctagatcata tcgaatacct tcttcatttt
    14401 ccgggtcgaa gttcatccct ttttcttctt ccaacagtcg cttcatttct tctaatatct
    14461 tgtttccttg ttcgcgtggt tcatcgctga acaattttaa tcggatttct tgtacttcta
    14521 cgggctgttt caactctttg atttgttcat ctaatgtgat accttttctt tttaattctg
    14581 gcaaaagcat caggatcttt gcgatgacat atgcaccatc atccagaaaa tagttttcct
    14641 tgaatgcagc gtgtccgctt gtttcgatgg ctagctgtgt atctttccca agacggttaa
    14701 gttctaatgc tttattgatt acatttcgat agccggaaat ataacgaact tggatgcctc
    14761 ctttttcttc aatgaatctt tgtagatgag aagaagtagg ggaattcgtc acgattcttg
    14821 ttcctggatg ctcttttaat acgattgtac ttaatactgc gatcaaatta tttcgattga
    14881 tcactgttcc agaagcactg acaactgcag aacgatccac atctgtatcg aaaatgatcc
    14941 caagatctgc ttcatttgct aaaacagcct gcttgatact ttccatcgct tctttattat
    15001 caggatttgg gatatgatta ggaaatcggc catctggttc caaaaattgg gaacctgttg
    15061 aatccgcacc taagctattc aatacttttt cagcaaagaa tccaccagca ccatttccgg
    15121 catcaacaat gattttccaa ccatttagtg gtttgctttc tagtgttcca atcccctttt
    15181 taatttttgt gactaaatct tgcgcataag gtgtcaaaag gtctgctttt tctacgcttc
    15241 cagtttgttc gctttttatt ttttgctgct gtgataggat aaaagcaata tcttcttttt
    15301 ctgctcctcc ttctgaggta aagaatttta ttccattata ataataggga agatggctag
    15361 cagtcagcat aaccgcagca tcgcacgaga actgttcaaa ttgagtggac ataaacatag
    15421 caggcgtagt agctaattcg aaatcgatga catgtatccc ttgttctttc agactttgga
    15481 tcaacgcctc tttcagtgct ggtccgctta tcctactgtc atgaccaatc ccaatcgtcc
    15541 attttttatt tggatcggtt gatttcttct ttttctttat ccagtttgct agtccccagc
    15601 cgatcttttt taccatgtct gtcgtcaagt ttacttcata tccttcaact ggtaatgcga
    15661 ttcctcgaat atccgatcca ttttgcagcg ctttcatatc tttcatataa aagtcctcct
    15721 catttattcc ctcatttttt ccagcttttc tgcaaatcgc tgtgcttctt cttctgagcg
    15781 gcaaataata atgaatgtat ctacaccggc catcgttccg acaacttcag ggtaagccac
    15841 ttcatctagc caattcgtta ccacatcggc accatttcgt tcagtcaata cgataaccat
    15901 gaactgaaca gactggatac gcaaaacctc gcgtctaatt gctgtacgca aacgttcttc
    15961 atttaaagaa acagatggct ggttaaataa tgtatagcgt actattttgt tttcattttg
    16021 actttttact aacttcattt ctcgaatgtc tcgagaaatc gttgcttgag tcacatcggc
    16081 gcctgcttca tgcagccgcg caagcagctc ttcctgtgtc ccaataggtt gttctgtaat
    16141 gatctggcgg atcagtgctt gtcgctgttt ctttttcata ttagacacct ctcaatgttg
    16201 attatagcaa aagataagta atatttcttc atattttggt attttttact tttatttttt
    16261 gttttcattc aggttgctaa cctttttcta ttttaacacg caaaatcgtc ttcatttttt
    16321 caggtgctga ttttcttgga tcgctgatgt aaatctcttt gtgttcttta gaagctcttt
    16381 catagccttc ttttgcgatg aatgcttcta atttctcaaa cgttgctggt tcttcggcat
    16441 agggcccgac gtgtaagatt tgggcacaaa gaccttcttc catctttttg aatactactt
    16501 gttctttcaa gtcttccgga agtttgctag aacgctgaat ggcttcttgt gctatcgctt
    16561 ctgtaacaaa gtcaggctgt cggatcatca attgataaga aaaatgttct tttttcatca
    16621 ctggttcatg caaatacttt tcttgcagtc cccattgtcc ttccagtgga tagacagtat
    16681 acatctgata atcaggaatc agccaatttt ttttaggcga catgcgtatt gcatagctga
    16741 ctgcatatag acaggctact cttcgtttaa agtcttcctg attcgggtcg ccgatccctc
    16801 tgatgctaaa gaatgatttt ttaggaacct ctagtatttg cgggcttttt ttcatactat
    16861 agctcttgtc tttacgccat tcaatttttt ccatttttct tcctccgcga aattccattt
    16921 agttatttat tatcatacct ctttttgagt gacttggcta atcgtgttga cactattttt
    16981 cagtttgtgc tagaataagt gaagtaaata aatcgtacag ataacacgtt tcggcgtgtc
    17041 gagagagagg cggtttctat ttttataata gaaatcactc tcttttttta cgaaattttt
    17101 tagaggtgat gtaaatgaca aaacaaaaac agctgctttt agtacctgca gtaattgcaa
    17161 cagggatgat gtcttttgcg ggcgtattga tcgagacggc catgaatgta actttcccaa
    17221 ctcttatcag acagtttgat ttaacgactg cacaagtcca atgggtaaca acgatttatc
    17281 ttttgatgat ttcgatcatt gttccgctgt ctacttattt gaatcgcaat tttagtctca
    17341 aaaaactctt tttagcttca aatctgcttt tcttggcagg tataatgatc gatttcttct
    17401 ctcctacctt catggtccta ttgtttggtc gattgctcca aggtgcagcg acaggtatcg
    17461 ctcttccgtt gatgttccat attatcttga catttgcccc cctcaatcga cgaggcgcga
    17521 tgatgggtgt cggtactttg acaacggcca ttgctccagc aattggcccc acttatggag
    17581 gcattatgac ttcacatttt acatggaatc atatcttcct gtttcttgtg cccgttttgt
    17641 ttctttcttt gattatcggc tggtttgcta ttcccgagat ggcagtacaa aaaagtggtt
    17701 atttggattg gataagcgtt ttaggaattt gtcttttgtt tagtggaagt ctaacatttt
    17761 tgagtacgtt gggaacagtt tccagctgga ttgctttaat catcggcggt attggctggt
    17821 tcctttttta ctatcgaagt aaaaaagtgg agcatccact gatccgactg tctattcttt
    17881 caaataaaac attccgcttg tttttgattg gcttcttagt ttatcagttt ttattacttg
    17941 gtgtatcttt tgtcttgccg aatttccttc agatcgttca aggaagtagt ccttttgtcg
    18001 ctggattagc gatgcttccc ggcgcagcgg ttggtgcttt gctttctcct ttttccggga
    18061 aaatgctgga tcaatatggt ccgaagaagc caatttttgc tgggctgatt ctttctttga
    18121 ttggttggct agcattattc ctactcatag gacacgcttc agtgggtgta ttgattgctt
    18181 gtcatgtgtt ttatatgatc ggtatcggat tatcttacag caatatgatg accaccggaa
    18241 tgaatgcact gaatgaagaa ctacaaggag acgggaacgc aatgttcaat accttgcagc
    18301 agttttctgg cgctgtggct acttcattag tagcggtcat tatcaattac gtccagcatc
    18361 atacttccca taactatgaa gtgtctacta cattaggatc aaaagcagca ttaggcgtct
    18421 tgttgctgtt gcttctcgta agctttgctc gattcgccta ttatctgttc tttgctaaaa
    18481 aagcgtagat tccatatacg gcaggtgttg catctgccgt ttttttgtgt gaaaatggtt
    18541 gtttgtaaaa ggaggctttt ttatggaaaa aattgccatt atcggtggcg ggatcattgg
    18601 tatgacccta gccagttact tagatacatc aaaattcaat gttgctttat ttgatgaagg
    18661 gacaggacag gcaactaaag ctagcgctgg gattatctcc ccttggttgt cgaaacgcag
    18721 aaacaaacaa tggtatcgtc tggctaaaga cggcgctgct tttttcccta aacttataaa
    18781 agatttccaa cttgatcaaa cgatttacgc acaatcaggg acacttttgc ttcgacctga
    18841 aaaagattta gctgaattgg ctgttcttgc cgagaaacga aaagaagaag cgccagaaat
    18901 tggaaacatc gaatggcttt cacctgaaca gacatctcaa gcacttccgt tattgaaacc
    18961 agcagtttca ctgcgtatca gtggtggtgg tcgtctggat ggaaaagcat atttagaaca
    19021 tcttggtcag cgtttagcac aaaaacaaat ggagcagatc caggcaaaag tcactttgca
    19081 taagaagagc gattcttggc tcatcaaggg accgtttgga gaatacacag ctgatcgtgt
    19141 aattttgaca cctggcccgg cacttaagcc tttattacaa gaattaggct atgctgcaga
    19201 tatacgtccg caaaaagggc agctcttagc atttcagaca tcttataaga tgagtcaaga
    19261 ctggcctgtt gctatgcttg acggagaagc tgatttcatt cctttcatgg atggaaagat
    19321 ccttttaggt gctacccatg aaaacgatca aggctgggat ttggctccta ctagcgaagc
    19381 ttataaggga ttgactaaga gtacagaaca gttcttgact gatccagatc agataaaaaa
    19441 ctggccatac gagttccgtg taggtacccg tgcttatacg tcagattttt ccccattttt
    19501 cggcgtactg ccagatgatc caagcttact ggctgctagc ggtctaggct cttctggctt
    19561 gaccacaggt ccttatatcg gctatctatt agccaacttc ttaaatactg gtcattggcc
    19621 tacggaagat tatcaaaagg acatctccac ctatattacg aaaaatccat catagaaaaa
    19681 cagctttttc aagtaaggat cccgagcgat attgcgcatg gattacttct tgaaaaagct
    19741 gttattttag ttcaatttct gaatcaaatt ctccaaactt tcttttgctt catctggcaa
    19801 gagatctttt cctatctgag cttcaatgaa tcgtaaacga atatcaagtc gttgtttcac
    19861 cagattttta taggacgtat cctcaaaaga aacaggaaaa tctggtatag gtaaatagtg
    19921 gatgtcttca aatggaccaa acgacttgaa ttctgccgtt tgttgcacga ttctttcaac
    19981 gattgacaat gtcgtttcag gtttgatttt tttatcatcg aaatatccag tattcaggac
    20041 atagcaggct gtttgctgtt tcaaaaacaa ctctcgaaaa gcttgatagt cttccctaag
    20101 aggatagaca cggaaaggat tagcaaatgg ttcaatgact agctcatcta gctgtctttt
    20161 tgtagtgata ttttccgcgt ctgatcgttt tgttgctaat gttgcaccaa aagacgctgc
    20221 taaaactggg tcattgatct tgataattgg cggaagcgaa tcatctttca tgatccaaaa
    20281 aacagcatcg atcttttcgc taagatgatc gactcggtcg ggtgtcgcat aacgtgattt
    20341 gactgtccgc ccatttccgt ttcgtatatc tcctgttact aggacttttt ctcctttact
    20401 tgtacatgtc acgcccacat tctgacaagt aaggaaagaa gaaatggccg gatcatcaga
    20461 cggatagtct tgtgttttat caaagtaaga aggttccaag gcagtagcaa aaccattttt
    20521 tcgagaaata acgaaagcat cgtcatgcaa gatcgaaaca gagtgacctt ccgtatgttt
    20581 tgctaaggta atcgttgatt ttccagaacc ggacaaccca aatacagcca tcgtataggt
    20641 ctggtcatta ctagcatatt gtttcatccc accgtggcag gcaataaagc cattgcgatt
    20701 tcccaatgcc caagcaagcg tcaaagtcgc tttttttaat tctccaaagt aacgtaatcc
    20761 tagcacagcc gctgtattat ggagagcatc aaacaaaatg agtccatttg gaaatgtttc
    20821 atgtgtccat tcgggatcac aaaagatata aagatctccc tcatcaaagg aaacagactt
    20881 ttgataagtc tctaagatct tcgaattcgc tggctgaaaa ttcagcaaat aagaatacaa
    20941 attgttctca aatccttctg gaatcagcaa atgactttgc acagaaaatt cttcagatag
    21001 gccaacgatt acttttgtat ggtaaaactg gcgcttgcga ctttgataca cagcttctct
    21061 taaaattttc tcgtatttgc tttgttcctt gtctaagtcc tcaaagatcc gccgagcact
    21121 tgctgttctt cccacaatgc ttccatcatt gaatactagt gtcctaacat cagctggtaa
    21181 atctagttct tcagcatgtg agattgttaa atctgtgatg atcgttcctg gactcccttt
    21241 tgctagttga taagctgtct tcctatcaaa aacttcatga acattattac cgtaaaatgt
    21301 cgtttctaca atcgatcgaa tactggataa cagtggattt ccacttgtga tttcgtttaa
    21361 ttcgagactc tcttttgtac tcatggctcc tcctcattcc ctaaacaaaa aaacgttttc
    21421 tttattatac attattcgag tttttatttg tactgctgcg ctgtgggaag caaacgagtt
    21481 atttttcaca caaaaaaacc gagaacttga ataaacaagt ttctcggttt catcattttc
    21541 cttttatcgg cttagtacca gccgtttgct aaccagaatg ttttagcagc atcccatgaa
    21601 ccataacgag atgttacata ttgttctgct acacgttctt gattggcagc tgaatagtcg
    21661 ccgtttaagt atgaagcatc taattgataa cggccgatgt aacgtccgtt agtagctgtg
    21721 tatgaaccgc ctgattcttt ttgtgcgatc cattcttttg cagagcttga agttggcgct
    21781 gttgcagcag ctggggcagc aggagctact tcaactgttt caacaggtgc aacgtatgta
    21841 tgttcttgcg ttgctgtttc agttgtagat gctgtatttt ctgttgtttt gttttctgtt
    21901 gttgctgaag aatcatttga agttgggatt gttaattgtt caccaacata aatgcggttg
    21961 atgtttgcga tcgaattttt ttcagcaatt gcatcgatca ttgagttgtc tcctgcaaat
    22021 ttttgtgaga tcttagataa tgaatcacct gattttactg tataaacttc atcagcgtga
    22081 gcatttgtag ttcctacaaa cattgcagta gcaccagcag caaaagttgt acctaaaaca
    22141 attttcttaa atgaattcat attaaactcc tttttttctc cgttttttat tctttcgacg
    22201 ctattaactt tatcatttag aaatatttca taggtaaaag aaacatgaca tttaatgaca
    22261 aaataacgaa ttatttaata tttgtaacat ttaaacaaat atttttttga tacaaaacca
    22321 taaaagcctt gttgtataag caaagtaatc gtttttctat gtttttttat ttttgaatga
    22381 aaaacgcaga ttctgtaaca ttcactgcaa taatccataa aaaaaagcaa aaaaattttt
    22441 gatttttatc aaattctctt aaaaaaatgt aaaaaataca aaaaaaccag taattgttac
    22501 aacaattact ggacaaaaac tttgaataat gttaactatt tttttatttt aactttctcc
    22561 gcaataattt ctgggcatgt tccaattcgt ttataacgac ttcttctgtt tctttagcta
    22621 atatttcatc taatacatca agccattttt ccggttcttt tgttcctaga cgtccaatag
    22681 cccaagctgc tgttcctctg atgacagggc ggacatctgt taaacattct gaaatctcag
    22741 gcaatgccgt tcgatcacct agattagcta aagcaatcaa tgcgtttctc tgcaaaggtt
    22801 tcttcccacg ccatgaacca gctaaatgcc caaattgctg tttgaagtct ttattagaca
    22861 tcgaaagcat tggctttaat tttggatata tttcgtctac ttttggttcc atctcttcat
    22921 gaaaatgaaa atcttttcct tgattgtaag ggcagactaa ctggcagata tcacatccat
    22981 aaatgacatt tcgcattttt ttacgatatt cttccggcat catccctttt gtctgagttt
    23041 gataagacaa acatcgctgg gcattcattc ttccgtcacc aagcaatgct tttgtcggac
    23101 aagcagtcac gcagcgcata cagtcaccgc aaccaaattc tcctggttta tcaggctcaa
    23161 atacaatatt agtaacgatc tcaccaagat agacaaatga accgaactct tcagtgatca
    23221 acaatccgtt tcgtccaata aatcctaaac cagctcgctg tgctacagcg acatcgatca
    23281 gttctccagt atctacttgc ggagctagac gccattcctc ttctttttgc catttttctg
    23341 ctcttgtttg gatgaattcg atcaatcggt tcaaacggtc tctgagtata tcatggtaat
    23401 cgatccccca agaagcacga gcaaactgcc cgcgtttttc atccctaggc acttcttcat
    23461 ggatcctagt aggatacgca agtgcaatgg aaatgatcga tttcggctga tcaaatgtca
    23521 tttctggata aagacgctca tcgatatttg gatgttcaaa gccagaagta tggccagctg
    23581 ctttttgttc ttccaacgat tcttttaatg aatcaaaagg ttccgccgtg gtgaacccga
    23641 ttttgtcaat tcctaatcgt ttgctttctt gtatgatttc ttcttttaat gtcatggtct
    23701 tcctcgcttg ctgttaacgg ctgtataacc cataatatag tttttctttt ttcagctgga
    23761 caaactggat ctgctgatcg gcaatcttct tttcttccat ccattttttt cttgcagcaa
    23821 atacttccca ataatttgtt gaaattaatt ttcttttgtt atctaatgca ttaaaaaaat
    23881 tcaatgaaac tggttttgta cttaacagtt catggagcct tacctcttcc catggcgaaa
    23941 actcagacag atcgcgggaa tacaatactt cttcatagag atttttttgc tgtgtgtacg
    24001 tgaatgtttg cgggattttc ccaggcctag caatttctac tagacgatta taaaacatat
    24061 tcattaattt gctgttggca ataaattgac ttttataata ggccgactgg atctttttga
    24121 ttactccttc tgctttgatg actgaaaata atgcaggcca tgctttgacg gttatttcgt
    24181 cgttttgttt aactaatacg ccaggtgtga agccgactgg agaaaggaac acaaaataac
    24241 cgataccggt attttcatct aaaggctgaa attcatcaaa caaccatttg cctatgtaca
    24301 gctcttcatc tggttctgtt gtctcatttt gatttgctat gaataattta gctaattctg
    24361 cttcaagaaa ttgaaggtct tgatccttgt cggtattttc ctgctggctg atcaatcgaa
    24421 agacttcttc tttaatcgta tatttatctt tacgtgtaaa attcatagcc acaccttcct
    24481 tccttactct aactataacg gaatttcttc aaaaaaggta tctgtacgac gaaaaacagc
    24541 ataatttttt ttcatatctc ttataaaaaa tgcaaggtct gctcctcaag ctagaccttg
    24601 cacttttcag ctttcttttg tttgtgacaa accttcatgg atcgtttcaa tattccattt
    24661 catcatctga tagtaagaat ctccttgttc tccttctttt gctatggaat cagtgaacag
    24721 tttatcatag attttcaaac ccgtttcttt tgctacccgt tccatgcttc ttgagtctac
    24781 actggtttcc acgaataaaa ccggtacttc ttttgctctt atctgatcaa tgatcgcttt
    24841 catttgatca ggcgtacctt gactttctgt attgatctcc catatataag ctgctggcaa
    24901 atcatatgct cgtgaaaaat acttgaatgc cccttcactt gttactaata attttttgtt
    24961 ctcttcgata gaagcaaaac tttccttcgc ttgtgtatct aattctttta gtttttccac
    25021 atatgcttct gcattttttt tatagagtgt cgcattttct gcatcttttt cagagaatat
    25081 acgtgcgatt tcctccacat attttattcc gttagatagg tctagccaag catggggatc
    25141 tgcttttgta tgttcttcac cgctagttaa ataaagaggt tctacatttt tgctaactgc
    25201 aaaataatct tttccttctt cttttttagc cgtttccatc aagttatcga accagctgtt
    25261 acctgtttca agattcaaac cgttgtataa aataacatct gcatcgcttg cctttttgat
    25321 gtcttctggt agtacttcat attcatgcgg atctgttccg actggtacga tactgtggat
    25381 atctatttga tctgttccga cctcttttgc catgtccgcc aagatcgaat tggtagccac
    25441 gactgacaac ttttctttac ttccttcatc cgcttggtca gaagcctgct ttccgcaacc
    25501 ggctaatacc aagaaactaa ctgccaagat taaaaagagt gatttttttg ttttcatcta
    25561 tctgcttcct ttctgaaata aaattccttt tgttggagaa aataaaaaag caaggataaa
    25621 aaatgcggta catgctaaca cgatcgtagc tcctgatggc caattgtaac tataactgaa
    25681 aaacacaccg acaactgcac ttagcatacc gattcctgca gctgtaatga tcattttcag
    25741 taaatggttc gttagcaagt aagccgtggc ggctggtgtg atcaacatgg caatcaccaa
    25801 gattgttcct actgtctgta aactgactac agccactaat gtcaaaaaga acatcaaaag
    25861 ataatggatc agcgatgtgt tcagcccata agcttttgcc attgtcggat cgaatgatgt
    25921 gatcttcaat tctttataaa agaaaaagac aaatatcaag acgattccac taacgagtgc
    25981 tgtcagcaac aaatcgcttt ccctaacagc taagacattc ccaaataaaa tatgatacaa
    26041 atctgtcgca ctctgggcat atgaaatcaa gataatccct aatgcaaaaa aggagctaaa
    26101 gacaattcca atcgctgtat catttttcaa tcggctccgc tgagtcacga aaccaatcac
    26161 tgctgctgtt agcatcccaa aagcagtggc tccaaagatg taactaaaac caaacatata
    26221 agaaatggct acacctggaa gaactgcgtg agagatagcg tctcccatca aagacatccc
    26281 tcgtaaaata ataaaagaac cgatgactcc agaagcaagt cctacaagca tggaagtgac
    26341 caaagcgtat tgcaggaatt gataattcat taatccatca ataaaggatt ggatcatttt
    26401 ttctctcctc cttttactaa atgtctgatg atctcaccat aggccaattg aaggttcttc
    26461 gatgtaaaga cttcttgtac tggaccggaa gcgatcagct gtttatttaa aagaataacc
    26521 tcatcgaaat attcttctac tttatgaaga tcatgatgga cgatcaaaat cgtttttcct
    26581 gaattcttca attcctgcaa gatgtcaaag atctttcgtt cacttaacgc atcaatccct
    26641 acgaatggtt catctaaaaa gatccattct gctccttggg ctagagctct tgcaataaaa
    26701 actctctgaa gctgtccacc cgatagttcg ctgatctgtc ttttggcata ttcttccatc
    26761 cctacttttt tcaaagcttg tcttgcacgt tctttttctt ttttcccagg tctttgtcca
    26821 attcgtaaag atggatatgt tcctaaaagt acaacgccta atacatcaat tggaaaggaa
    26881 agatccaatt cacttcgctg ttccacgtag gctatttttt tacggactga gtttaccgac
    26941 tgtccagaaa aggtgacttt accagtagta gctggtatca actctagcaa agatttcata
    27001 aatgttgatt ttcctgcacc gtttggtccg ataataccgg taattttttg tggatttatc
    27061 gtcaagttga tagttttcaa aacagttttc ccttgataag cggctgaaag gtcttgaatt
    27121 acaatggccg tacgttccaa atcttacact cctttttagg tttacctaac tttttattta
    27181 aatatagttt aactaaaatg gaaagcattt tcaagtagaa tgatgaaaaa gtttttttcg
    27241 aattttcctc gcattttatg aaaattttct gtagaatcac atcaagagtt caataaggct
    27301 aacctaataa tgaaaaacat gtgttgaaac gtttgattat tttttcttgt tgactcaaca
    27361 acgaaaggag tttttgtatg gaagaagaaa agttaactcg aagtcttagt gcccgtcata
    27421 tccaaatgat cgcactaggt ggaacgatcg gtgtcggtct gtttatgggt gcctcctcaa
    27481 ccatacgttg gacagggccc tcagtgatgg gagcctatgc gattgcagga ttctttttgt
    27541 atttgattat gcgtgcttta ggcgaaatgc tttacgttga tccttcgact ggttcttttg
    27601 caaattacgc gagcgagtac atccatcctg tggctggcta cttgaccgct tggagtaata
    27661 tttttcaata tattgtcgta ggaataagtg aagtgattgc tgtaggatct tatatgaatt
    27721 attggtggcc tgatttgccg gcaattattc ccggaatcat tgtcgtcttg tttcttatgc
    27781 tggcaaatct tatttctgtc aaggcgtttg gcgaattaga attttggttt tcgatcatca
    27841 aagtcataac gatcattttg atgatcattg caggtcttgg ggtaatctta tttggatttg
    27901 gtaatcatgg tcaggcagta gggatttcaa atctttggaa aaatggtgga ttcttcactg
    27961 gaggcgtcaa aggatttttc tttgcattat cgatcgttgt tgcttcctat caaggaatcg
    28021 aactgatcgg aatgactgct ggtgaagcag agaatcctaa aaagacgatc attgaagctg
    28081 tccagtccac tatcggtcga atcttgattt tttatattgg tgctattttt atcattgtga
    28141 gtatctatcc gtggaatcaa ttgagtgaga ttggttcacc ttttgtacaa actttttcta
    28201 aagtcggcat tacatttgct gcaggactga ttaattttgt cgtgattaca gcggcattat
    28261 caggttgcaa ttcagggatt ttcagcgcaa gtcgtatggt ctatacactt gccataaatg
    28321 gaaagatgtc taaaaaattt ctgaaactat ctcgtcacgg tgcgcctttt tatcctgtcg
    28381 tagcaatctc aggtggaatc ttaattggtc tgatcttaaa ttatcttcta ccaatgttca
    28441 tcaaccagtc agaaaatatt ttcgttttcg tatacagctc aagtattttg cctggtatgg
    28501 ttccttgggt agtgattttg atcagcgaga ttcgcttcaa aaagaagcac gcagataaaa
    28561 tgcatgatca tccttttaaa atgccactat ctccttatac gaattatgtg acacttgctt
    28621 ttttagctat cgtattgatt ttcatgttta tcaatcctga aacgagaatc tcattgatta
    28681 ttggactcgt tttcttgctt tacatgacga tccattactt tgtacgcgaa aaaagaaccg
    28741 gaaaataaaa aaagaacgaa gcttcacctt agtggaagct tcgttctttt ttattgcttt
    28801 tatcaattca attttagcgt ctcaccggga gtcaggaaat aattctccat gctcatccca
    28861 ttcagcgaca agatcgtttc tactggtacg ccagttcgtt cggctatttg atttggacct
    28921 tctccttcca aaactacggt tgtcgcagcc tgtgaagtcg cgctgttggt attagtttca
    28981 gaggaatctg ttgtgtcttg tgttgttcga gcttgcattt cagaagcttc taccgactct
    29041 gctgtctcag aatcagaaga tgttgtgtct tgtgtgcttg ttgactctgc ttgaagagag
    29101 gcgctagtct gcaaataaat atcggaaatc ttagcgacat gattcgtata attagccgat
    29161 aattgattga tcaaagtatc taagtctaca ccgtctttat tttctgctgc ctgatacgct
    29221 gcacgtaatt ttctgatccc ttcgtcggag attgcttgaa gctcacgtgc tttttggtta
    29281 gcaactgctg ataaaccagc tattccctct tgatttccct gaatttctgt ctggtattct
    29341 tcaatcaatg caggcgtctt ttcttcgatc tttttcgaat aatcatttac gattgcttga
    29401 agttgctctg gcaaaccatt tgctgttttt tcttcagaag tttgtgtctc ttttgtttta
    29461 gttgatgact cacttgtttg tttcgtctct gttttctttg tcgttgtttc cgttatggtc
    29521 gtacttttcg cttctgacga attttttcca tgaaaatata gacccgcaac tcctcctgct
    29581 atgatcaaaa acacggcaac tgctgcccca atcatgatca tccgcttacg agctgcctgt
    29641 ttttgctgtc ttcttcgggt catccgaaca ttttctcccc actcattttc atcatacatt
    29701 tttttcacca ccaattttta tgtataatag cgttatcaaa cgcttcatat tcttattgta
    29761 gcaaataatt gtcgctgtgc acatttttat ctttgttatt tataagaaaa tttcaccagt
    29821 tgagatgatt ccaagattgt ccgtcgattt ctccttgcag ctgcattgtt cgttcgtcta
    29881 tctcagccat cagtttcttt atttcatata agagcgcacg gtcttgatat tctgattttt
    29941 cgcttaattc atctaattgt tggatcagcc aatcatttgt cataatgaag ttcctttcat
    30001 ttcttgcagt gtaaaggtca agtcttcgat ctgctctttt gcctcagtca gtgcttctac
    30061 gatatatgct tgtttttcag attcttcttc ctgcattttc tgattttcct gtactctttg
    30121 aataaaccag tcaatccgct gagtcagcga tggtttgcct tccaatgaga gatactgctg
    30181 ataagcaatt agcttctccc aacgtttttc ctgggataaa tacataaatt gtgctaaaac
    30241 gaatggcgga agataggtca tatggaattt atttgcgatt cgctgatacg gcctcaaaaa
    30301 ttcggaaatc gtatattctt cttttcctcc agcttggtat tctttttccg ccacacctgt
    30361 tgtcaatacg attcctagtt ctttcccttt taatacatgt gctgctcgtt ccaagacatt
    30421 atcttgccaa atttttaaat gagcaggaga actataccag taaaacggaa actggaaaat
    30481 gatccgatca tgctgggcca agagctgtag ttcagtctct atatctattt ttccgtctgg
    30541 ataacttgat tccaaatgat gccaagtagc tggtaaacca gcagaagctt ctttgaaaaa
    30601 ttgctgattt aaagattctt cgatcgttgg atggctaatg atgataagtg tacgcatccc
    30661 ttttcctcct ttttagtctt cgctttacag tgtagcataa ccgccacaag tttcttttgc
    30721 cgatgcttgt cattttaacc agactaatca ggttgtccaa gaaactgcgg tttgtttttc
    30781 caactgtttt ttcaaggtat ccaaagcaat attcttaaaa ttttcgtttt tcatacgttt
    30841 acgatagttc gtagccgttt ctccggtact ctttttgaac attcggctaa atacgactag
    30901 actattgaac cctacttgat aggcaatact ttccacggat tcatccgtca gagaaagaag
    30961 aaacgcccct cgattgatcc gtaccccgat caaatattcc ttgatactgg tacccatatg
    31021 atttttgaat actcgcgaca aatggctccg attgaccgct aaatgctggg cgatttcctc
    31081 aacagacaat ttttcagcat aatgtgcctc gatgtatttg actgtttcaa cagctaaaga
    31141 ggaatgaacc ttttgtacac caccgctgac ctttccgcca tcttttaaaa ggactgataa
    31201 aaaacggtag gttaatgctg ttaactgtaa ttcattttcc aaggtttctt ccgtatcttt
    31261 catgcattct aaaataatgt cgatatattt ttgtatgtca gaagagacca tcgtgtattg
    31321 gtcttctctg aaaagcgact gccgaatgat ttcttctgca gcactcccac caaatgaaag
    31381 ccagcaatac atccacggat cttctccatc tgataagtaa aacgtcgagt ctcctggacg
    31441 aatcaagaac agatcacctt ttttcaattg gaattgttga tttttcacat gataagatcc
    31501 tttgccttcc atcacgacat gcaggatgta atcattgcga atagcaggac caaaagaatg
    31561 aaacggcatc gttttagaga aaccacaaaa atcaaaatac aattcttttt ctacttgttg
    31621 atgttccttt tttaaaaaaa tcgattgctc cacgtctatc cctccttact cctttagtat
    31681 aatgcaacaa aaagttaaat aaaagtcaca gaaatatatt aaaaaggaag cgatttcttg
    31741 ttaagtttaa gtcattaaaa gatctttgtt attcgttgta accggtttac ttagtattat
    31801 atattgaaca ggagaggaat acagattatg aaaagcaaaa tgatccaacg tgtgtcctac
    31861 gctttaggcg cttttggaca cgacacattc tatgttacat taagcactta ttttatggta
    31921 ttcgtgacaa gccagatgtt cgcaggaaca gataaggcaa cgaatgcaaa aatgattgct
    31981 acagttacaa gcttagttgt aggtatccgc ttagttgaaa ttatttttga tcctttgatt
    32041 ggtggcatca tcgataatac tcgtacaaaa tacggtaaat tcaaaccatg gttagttatc
    32101 ggcggcgttg ttagttccgt actcttggta gcaatcttta ccaatttctt tggcttagct
    32161 actcataata cgactttatt tatcatatta tttgcaatcg ttttcatctt attggatagt
    32221 ttttattcat ttaaggatat cgctttttgg tcaatgattc cagctttgag tacggaaaca
    32281 aaggaacgtg aaaaatttgc tacgtttgct cgtttcggct cttctctagg tgcaaatggt
    32341 actactctag tcgttgtccc tatcgttact ttctttacct atcttgttac tcataaacat
    32401 attgaaggcg cttcaggctg gttctggttc ggtgtgattg ctgctgttat ttcaggcggt
    32461 actgcgatta tcactgcctt gggcacaaaa gaagtcgata ctgcgatccg tcagcaaaat
    32521 gaaaaagctg ggatcaaaga tgtgttcaaa gcagttgctc aaaatgatca gttgatgtgg
    32581 cttgcccttg cttatatcgc ttatgcgatt gccaatgcag caacaactgc cgtattattc
    32641 tacttcttca aatatgtact tggccaacca actgaatttt ggatcgttgg tctagttgct
    32701 gccttacttg gtttagtagc tgttccacta ttcccaatgc ttacacgcgt catctctcgt
    32761 cgctacgttt accttggagg gatcgcaatg atgatttctt cttacttttt ctttacgatc
    32821 gcaggttcaa gtttgccaat cgttatcatc gggctagtat tgttctactt ccctcaacaa
    32881 ttgattttct tatccgcttt gatgacgatc acagactctg ttgaatatgg tcaatggaaa
    32941 aatggtatcc gtaacgaagc tgttactcta tcaattcgcc ctttactaga taaaatcgct
    33001 ggtgctttgt ctaacgggat cgtagggttt gtcgctatcg cttctgggat gactggtaat
    33061 gctactgctg ctgatatcac tgctcatggc gtaacgactt tcaaagctta tgcattctat
    33121 gctcctgctg ctttgatgat tttctccgct attatttttg cttggaagat tacattgaca
    33181 gagaaaaaac atgcacaaat cgttgagaaa ttggaaaaca aattggctcc agctgataca
    33241 atggaagatt aacttcacga tgcagtagtt ccttcccatt aagaaaggat cttgaaaatg
    33301 aagattacag aaaaagattt tggccaaggt tatcacttga taaccttgga gaacaaaaac
    33361 aagctagcac tttctatctc tgatttaggt gctagaatcg tcagtttaaa atcaaatgat
    33421 cgagaattag ttttgggatt tgacaccgct gaagaatata tcgaaaaaga tccgtatatc
    33481 ggtgcttcta tcggtcgcac cgcagggaga atcgaaaatg gccgcttttc tctcaatgga
    33541 aaaacttacc aattagccac agatccaaaa actggacata atctgcatgg tggtgctcct
    33601 ggatttgaat taaaaaaatg gtcttatgtc attttgaatg gcgaaaatga agcttctgtc
    33661 atttttacta ctacaagtcc cgacggagaa catggttttc caggtacaat ggatgtggaa
    33721 atccgctata ctttgacaaa agataatatc tggcgagtga cctctcgcgg caccagtgac
    33781 caagatactt tattcaatcc gacaaatcat gtttacttca acttgacggg agatgcttct
    33841 cagtcaatcg atcaacatga gctttggctc aatagcgaag cttatgctcc tttgcgaaca
    33901 gatagtattc ctataggggt aaaagaaaat gctgcaggaa gtgctttcga ttttcaaata
    33961 cctaaaaaat tagcgtccgt ttttgctagt gatttggatc aaaaaaatct tgttgacgga
    34021 atcgatcatc catttttctt aaaagaaacc ggcttgggta aagaagccgc tcgcttgact
    34081 agccccgata aaagaatcca agtagatatt gctacagatg cttctagtgt ggttattttc
    34141 actgcaaatt tcggcacaga aacaccagaa atgcgcaacc gaaaactggc acatcacggt
    34201 ggcatcacat ttgagactca aacagctcca ggtgcagagc gcttctcagc atttggttcg
    34261 attcatttaa aagccggatc agtatttgaa acagtaacag aattcaaaat caaaacaaga
    34321 aaggaataac tcatcatgga aatcaaaaga agcttaaaca caaaatttgc cgaaacattc
    34381 ggacctaaaa aaactacaca atacttctca ccaggacgca tcaatttgat tggtgaacac
    34441 acagattaca atggaggcca tgtcttcccc gcttccatca cttatggaac gcaaggtgta
    34501 gcagcacctc gagacgataa taaaatatta gtttattcca caaactttga cgatatcggt
    34561 gtcattagtt ttactttaga tgagctagaa tatgataaaa aagcaaactg ggcaaattac
    34621 gtaaaaggaa tggtccttaa attaaaagaa gctggacact caatcgatca tgggtttgag
    34681 ttattagtgg aaggaacaat ccctaatggt gcaggacttt ccagtagcgc ttcattagaa
    34741 ttattagtag gtgttgtatt agaagatctg tttgatttaa aaacagatcg cttggaacta
    34801 gtccaaacag gtaaaaaagt agaaaatgaa ttcatcggtg tcaattcagg tatcatggat
    34861 cagtttgcca tcggcttcgg tgagctagat catgcaatct tattagatac aaatacgctg
    34921 aaatacgaaa tggttccagt gaaactagat ggttatgcaa tcgtcatcat gaatacgaat
    34981 aagcggcggg aattggcaga ttcaaaatac aatgaacgcc gtagcgaatg cgaagaagcc
    35041 ttggcacgtt tgcaaaaaac tttgcctatc tcttctttag gagacttaga tgaagaagaa
    35101 tttgaatcaa ctattgacca aatcggcgat gatacattga tacgcagagc tcgccatgcc
    35161 gtttctgaaa atcagcggac tttgaaggca aaagctgaat tagaagctgg gaacttagaa
    35221 gcatttggtc aactgttaaa tgattctcac cactctcttc gctatgatta tgaagtaact
    35281 gggatcgaat tagatacact agtagatgct gctcaaaaac aagaaggtgt cttaggtgca
    35341 cgaatgacag gagctggatt tggtggctgt gcgattgctc ttgtcaaaga agaaaatata
    35401 cctgccttca aaaacaatgt ctatgatgaa tacatgaaag ttgtcggcta tgctccggaa
    35461 ttttatgttg cacacattgg aaatgggaca acaaagatcg atccagaagc tgttcatgtt
    35521 tgataaaaaa atcaacgatc tcagctaaaa acaaatagat aaaaataacc tctcagcaat
    35581 ttccaaatgt gagccttttg ctcgtatttg aaaattgctg ttttttattg acacggaaag
    35641 agaacgtgtg ttctaattgt gttgaagagg tgattgttat gtgggcgaat caaaatccgg
    35701 tatttgttta tgaaaaagaa ccttcaagag atattttatg tattgactgc aaatcttttt
    35761 acgcctccgt agagtgcgtt gaaaaggatc ttgatcccct tacaactaaa ttagtagtca
    35821 tgtcctatcc gtccgattcg acagaaacac ggggtagcgg attaatcttg gcttccagtc
    35881 ctgcagcaaa aaaagcttac ggcatcacca atatcagccg tgccagagat cttcccttcc
    35941 cctatccaag tgatttatat attgttgccc caaggatggc ctattatatg gaaaagaaca
    36001 gagaaatcaa ttctatctat aaaaaatatg cagacgaagc gaaccatcat gtctattccg
    36061 tcgatgaaag cttccttgat gtaacaaata gcatggcact ctttggtaaa acaaatgcgt
    36121 acgacatggc taaactgatc cataaagatg tgtttgagca gaccggaatc tacacgacta
    36181 taggaattgg cgataacccg ctacttgcta aactagcctt agacaatggc tcaaaagacg
    36241 gaaagcaaat gtttgctgaa tggcgttatg aagatgtacc agaaaagtta tggaaaatct
    36301 cagatatcac tgacttttgg ggaatcggca aacgaacagc aaaacgtctg aaacaaatgg
    36361 gtatacattc tgtttatgat ttagctcacg cggattatta tcacttgaaa agcaagctag
    36421 gggtcatcgg tactcagctt tatgcccatg cttggggcat cgatcgaagt tttttgggac
    36481 aagaatatac accaaaatca aaaagtatcg gaaatagtca aatcctagat agagattata
    36541 caagacgaga agaaatcgag atcgttatca aagaaatggc cgaccaagtc ggcactcgct
    36601 tgagacgatc tgcagcaaaa acacaagtag tcagcttatg ggtaggatac tctttaggct
    36661 atcttgatcc aaatggcaag accgggtttc accagcaaat gaaaatcgaa gcgacaaatg
    36721 ctagcagaga tcttgcagat gctttattga ccattttcca ccagcattac cactaccagg
    36781 atattcggcg tgtaggcgtg aactgttccg acctcgtata cgcgacaggt ttacagctta
    36841 acctttttga agatcctgaa aagcagataa atgaagcgaa agttgatttt gttgtcgata
    36901 cgattagaaa aaaatacggc tttcaatcaa tcatccatgc gcatagtctc ttgcaaggag
    36961 gacgcgccat cgcacgtagt tctctcgttg gcgggcatgc aggtggtatg agtggattag
    37021 aaggtggaaa agatgagacg gacagcaaaa aaattcattg actataacga gtatcgagat
    37081 cggccatttg gattaaaatg ggggactgct tttgcgatgg aagaactagt caacggtatc
    37141 aaaaaaatga agaagaagca cgcaaacagc ctcttcctaa acaacaaatg acattgcaag
    37201 aaatcgatag tatactgaca gaagcctttt tatctcgtaa agcagtaatc attcagctca
    37261 atttaaaaga tgaatttgga agactcttgg atgaggtcga agggcacttc attggtgaag
    37321 cctatgaaga ttactttatg attgaccatc agccgatatt gtgggaagac gtacggtata
    37381 ttgagttaaa ggaaacaaaa aaatggtttg tgacatgaga ggttgtgaca gaagtgatca
    37441 acttcaaaaa ataagaaagg atttttcgaa aattgcttct taaatttttg tggaattttg
    37501 gcttattttt cgaagaagca acttctggaa caacgtatat tagatatcag aggttgtgaa
    37561 aaagtcgctt agttttgagt aacaagccaa ggcgctgatt tcacaacctc tgtctatcta
    37621 tccatctatt cggtaagatt catgcatgac gtcttcttta tttagtatgt agagcccttt
    37681 ttcttctgac cattcaacat aaatcagctg ttttacatct gcatagcctt ctttcttcaa
    37741 gttctccata agccatgctt cagtcaattg attggactga agcactttat gctgaatttg
    37801 cccttcatct acaagcagga tcgataaagc tttgtcttca tctgattttt tcaatacact
    37861 catttgaccg gcattctcta ggataacatg tttggcattt tcaagaaaaa agcattcttg
    37921 ctgtcttaag attgctcgca actgctccat ctcgatatgg ttatttgtca actctgtcat
    37981 gttgatgacg ccgtctttga ttagaacaga tggctcgcct ttgacccaac gattgacctt
    38041 ttcatttttt tggacgatac gttcgatacc ataaatcatt actgcccaaa gcgcaatggc
    38101 aaataggaca tgccctacat ggacattgtc atcataggtt gattcttcta agatcccacc
    38161 taaaacaagc gtatagacta aatcaaacgg tgtgatttct gacatggatt tcttcccaag
    38221 caaacgtacc actaataata aaccgatcaa cccgaacacc agtttcattg taattgaaaa
    38281 aatcattttt tctcccccta actatctgtt aattaaatta tatatgcttt ctcacgaaca
    38341 cgcatggaat atacaaggaa gaaatgtatc cttttactaa aaaaaggact gtgacactgt
    38401 agtgaccccc aaaagttaga cttttttgga gtggagaaat ccactccttt tttttatgct
    38461 ctaaaatgat atttttacac aaccgttacg gttgttttac gaaattggac g
//
LOCUS       DAFLWC010000015        37129 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.015, whole genome shotgun sequence.
ACCESSION   DAFLWC010000015 DAFLWC010000000
VERSION     DAFLWC010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37129
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.015"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            299..1960
                     /locus_tag="L1V17_000758"
     CDS             299..1960
                     /locus_tag="L1V17_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1235542.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(2030..2392)
                     /locus_tag="L1V17_000759"
     CDS             complement(2030..2392)
                     /locus_tag="L1V17_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HBN1235543.1"
                     /translation="MKEQSNEKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFL
                     WSLPFLIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSTLSSASYGMYSFWLII
                     AGILIALSAIFMLFSLLG"
     gene            2460..3401
                     /locus_tag="L1V17_000760"
     CDS             2460..3401
                     /locus_tag="L1V17_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1235544.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3402..4445
                     /locus_tag="L1V17_000761"
     CDS             3402..4445
                     /locus_tag="L1V17_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1235545.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4451..5521
                     /locus_tag="L1V17_000762"
     CDS             4451..5521
                     /locus_tag="L1V17_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1235546.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5511..6464
                     /locus_tag="L1V17_000763"
     CDS             5511..6464
                     /locus_tag="L1V17_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1235547.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6476..7486
                     /locus_tag="L1V17_000764"
     CDS             6476..7486
                     /locus_tag="L1V17_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1235548.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7771..8592)
                     /locus_tag="L1V17_000765"
     CDS             complement(7771..8592)
                     /locus_tag="L1V17_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBN1235549.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8689..8967)
                     /locus_tag="L1V17_000766"
     CDS             complement(8689..8967)
                     /locus_tag="L1V17_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235550.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9235..11244
                     /gene="metG"
                     /locus_tag="L1V17_000767"
     CDS             9235..11244
                     /gene="metG"
                     /locus_tag="L1V17_000767"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBN1235551.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11723..12310)
                     /locus_tag="L1V17_000768"
     CDS             complement(11723..12310)
                     /locus_tag="L1V17_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235552.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12485..13807
                     /locus_tag="L1V17_000769"
     CDS             12485..13807
                     /locus_tag="L1V17_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1235553.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13962..14738
                     /locus_tag="L1V17_000770"
     CDS             13962..14738
                     /locus_tag="L1V17_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBN1235554.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14731..15300
                     /gene="rnmV"
                     /locus_tag="L1V17_000771"
     CDS             14731..15300
                     /gene="rnmV"
                     /locus_tag="L1V17_000771"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBN1235555.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15293..16177
                     /gene="rsmA"
                     /locus_tag="L1V17_000772"
     CDS             15293..16177
                     /gene="rsmA"
                     /locus_tag="L1V17_000772"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBN1235556.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16628..17257
                     /locus_tag="L1V17_000773"
     CDS             16628..17257
                     /locus_tag="L1V17_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235557.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17381..18490)
                     /gene="ugpC"
                     /locus_tag="L1V17_000774"
     CDS             complement(17381..18490)
                     /gene="ugpC"
                     /locus_tag="L1V17_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBN1235558.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18699..19121
                     /gene="mgsA"
                     /locus_tag="L1V17_000775"
     CDS             18699..19121
                     /gene="mgsA"
                     /locus_tag="L1V17_000775"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBN1235559.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            19444..19980
                     /locus_tag="L1V17_000776"
     CDS             19444..19980
                     /locus_tag="L1V17_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBN1235560.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(20020..21783)
                     /locus_tag="L1V17_000777"
     CDS             complement(20020..21783)
                     /locus_tag="L1V17_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1235561.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(21786..23501)
                     /locus_tag="L1V17_000778"
     CDS             complement(21786..23501)
                     /locus_tag="L1V17_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1235562.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(24280..24504)
                     /locus_tag="L1V17_000779"
     CDS             complement(24280..24504)
                     /locus_tag="L1V17_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235563.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            24695..27472
                     /locus_tag="L1V17_000780"
     CDS             24695..27472
                     /locus_tag="L1V17_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBN1235564.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            27553..27972
                     /locus_tag="L1V17_000781"
     CDS             27553..27972
                     /locus_tag="L1V17_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBN1235565.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            27984..28454
                     /locus_tag="L1V17_000782"
     CDS             27984..28454
                     /locus_tag="L1V17_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1235566.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            28471..29250
                     /locus_tag="L1V17_000783"
     CDS             28471..29250
                     /locus_tag="L1V17_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1235567.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            29237..30058
                     /locus_tag="L1V17_000784"
     CDS             29237..30058
                     /locus_tag="L1V17_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBN1235568.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            30075..31124
                     /locus_tag="L1V17_000785"
     CDS             30075..31124
                     /locus_tag="L1V17_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBN1235569.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            31137..32141
                     /locus_tag="L1V17_000786"
     CDS             31137..32141
                     /locus_tag="L1V17_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBN1235570.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            32774..33793
                     /locus_tag="L1V17_000787"
     CDS             32774..33793
                     /locus_tag="L1V17_000787"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBN1235571.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            33836..34717
                     /gene="galU"
                     /locus_tag="L1V17_000788"
     CDS             33836..34717
                     /gene="galU"
                     /locus_tag="L1V17_000788"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBN1235572.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            35017..35394
                     /locus_tag="L1V17_000789"
     CDS             35017..35394
                     /locus_tag="L1V17_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235573.1"
                     /translation="MGKLVAVAQSLLDILKWLMVGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            36000..36614
                     /locus_tag="L1V17_000790"
     CDS             36000..36614
                     /locus_tag="L1V17_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBN1235574.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
BASE COUNT        12155 a         6496 c         7585 g        10893 t
ORIGIN      
        1 tcagataagg gactgtgaca agacttttgt cacagtttct ttttgtttat tcttttttat
       61 ctttgtatgg caataataga caatataacg aaaattattt aatggctttt ggaagaccat
      121 ggaaaacctt gtacaaagct attttttctg aaaaattcct tgaaacctca cgaaaaaatc
      181 attattttat gaaaaagaca aaaaaaagtg ttgatttttt aataattatt cattaaactc
      241 ttaaacaact tcagaaaata ttaattattc tgaaaattcc aataaagggg tacgtaaaat
      301 gaaaaagaaa tttacatttg gtttggttgc ggtatgcggc cttgtacttg ctggatgtta
      361 tggcggcagt tcagccacaa gcagtagttc agcaaaaagc ggttcagcag atggaggagg
      421 cgtatttaac ttagtcgtgc ctcaagaaat gcctacagct gacttatcag ttgcaacaga
      481 tacaatcagt tttacagcat tgaataacgt ttatgaagga atttaccgtc ttgatgaaga
      541 cagcaaacca cagccggcag gagctagcga gttggcagaa gtcagtgaag acggattaac
      601 ttacaaaatc aaattacgag aagacgcaaa atggtcaaat ggtgatcctg ttacagcagc
      661 ggattacgtt tatggctggc aacgaacagt agacccagct acagcttctg aatatgctta
      721 cctgtatgcg ccagttgaaa atgcagaaga cattacagct ggaaagaaag ataaatcaga
      781 actagggatc aaagcagttg gtgactatga attagaaatc aaattgacga aacaaacacc
      841 atatttccaa tatctgcttg ctttcccatc atttttccca caaaaacaat ccgtagtgga
      901 agaaaatggg gatgcctatg catctgcaag tgataaagct gtttataatg gaccattcac
      961 attagaagat tttgatggac caggaacaga tacagaatgg acttataaga aaaatgatca
     1021 ttactgggac aaagatacag taaaactttc tgaaatcaaa gtcagtgtag taaaagaatc
     1081 ttctactgca ttgaacttat tcaaagatgg ccaagcagat gacgtgatct tgtctggtga
     1141 gttagcacag caaaacgcaa acgatccagc ttatacttct gttaaagaag cgcggacaag
     1201 ctatatcgaa ttcaatcaac gtgaaaagaa ttcaccattc aacaatgtga acctaagaaa
     1261 agctatttct tattctatcg atcgtgaagc tttagtaaaa caagtactag gtgacggatc
     1321 agttgtctct acaggattga tcccatcaga tatggtaaaa agtccaacaa cgaacgaaga
     1381 ctttgcaaaa gaagctggaa aattagtttc ttatgacaaa gataaagcaa aagaatattg
     1441 ggaaaaagcg aaaaaagaat tgggcgttga ttctttagaa tttgatttga tggcttctga
     1501 tgatgattca tcgaaaaaag taatcgaata tgttcaaaac tcaatccaag aaaacttgga
     1561 tggcgtaaca gtcaaaccaa cacctgttcc attctctgta cgtcttgacc gctcaacttc
     1621 gggtgatttt gacgcagtac taggcggatg ggctgctgac tatgcagacc caagcagctt
     1681 tactgatttg tttgtcacag gtaattcata caaccgtggt cgctggagca atgcagaata
     1741 tgacgaagca gttaaagcag cttcatcaac agacgctggc gatgaacaag cccgttggga
     1801 tgatttccaa aaagcaatca agatcatctc tgatgatatg ggtgtcgttc cggtgtacca
     1861 aaaagcagaa ggtcacctag tgaatgaaaa aatcaaaggt atcgttcacc atgcggcagg
     1921 cgcttcatgg gattacaaat ggacatacgt tgaagaataa tcgttaatac cgtgagcatg
     1981 agaaaaaacg aggctgcggc aaatgtcgca acctcgttct catattcact tatcctaaca
     2041 aagaaaaaag catgaaaata gcagaaagag caattagtat tccggcaatg atcagccaaa
     2101 agctgtacat accgtagctg gcagacgaga gcgtggaaaa ttctggtttt ttctttcggt
     2161 tccttgttcg tgcaagatgg accgatcgct gaaaatgatc gaagaaaccc gaagaaaaga
     2221 cccataaaaa accgccgata atcagaaacg gcaatgacca taagaataga tcattagata
     2281 attgaatgag tgtaaaggaa tggttgatga gattttttat taaaataacc agaatcagta
     2341 gaaaagctac tgcgtagggg atagattttt tttcatttga ttgctccttt atttttggtt
     2401 cattatctaa taatgtagcg aaacatctgt cagaagtcaa aagctagggg gaaacattag
     2461 tgaatagtta tatcaaatat gtattaaaac gtgtcttttt catgatcatc acgctttggt
     2521 taattgcaac aatcaccttt ttcttgatgc aattgctgcc gggcacgcca tatacgaatc
     2581 aggaacgttt gagtcctgaa acaatcgaga tgctaaataa acaagtcggt ttggataaac
     2641 cagttatcgt acaatatggg atttatcttt ctaatttgct tcaaggagat tttggaattt
     2701 ccttccaatt taaaaaccag ccagtcgcac atttgttagc tggaagaatc ggaccatcct
     2761 tgcagttagg gttacaggca attatctttg gaacagtcct agggacgatt ttaggaacga
     2821 tctctgccat gaagcaaaat acatgggcag atacatcttc tacactcgta gcgatattag
     2881 gtcgttccat tccaaacttt gtatttgctg ttttattaca atatatcttt gcaatcaaat
     2941 tacaagtttt gccaatcgca aaatgggatg gctttgtgta cacaatctta ccaacaattg
     3001 cgttggccat gtcgccgctt gctgactctg ctcggtttat ccgtacggaa atggtggaag
     3061 tactgcatag tgattatgtg gaattagcaa aagcaaaagg attgagccgt tgggaaatcg
     3121 cctttaaaca tggtcttcga aatagtttga ttccattgat gactttatta ggaccgttag
     3181 ctgtagcatt gatgaccgga tcactggtgg tagaaaatat ctttgctatt cctggtatcg
     3241 gggaacaatt cgttaagtca atcacaacaa atgattatcc tacgatcatg gctgtaacga
     3301 tcctttactc atttatgctg atttttgtta ttttgatcgt ggatctattg tacggtctag
     3361 ttgatccaag aattcgtgtt tcagaaggga gccgaggata aatggaaatg ataccaaagc
     3421 gttatgaaac agttgcagat atccctgcgg atgaatttct tccattacaa aaaaataccg
     3481 aagaagaacg tgaacagatt actgcacctt ctttgaattt tatccaagat tcatggcgcc
     3541 gtttaaagaa aaacaaagct gccgttattt caatggtttt actattggtc atcattttga
     3601 tctctgtgat cacaatcttt gtttctcctc atgatccaac tgcccaaaac gtggcttata
     3661 tcaatttgcc tcctcgtatt ccgggaatca atatcgatgg attgaatgga aaagcaatgg
     3721 ttggtggtga acttgttgat aaatatgctc aagcaaacgt cccttcaaac gtaaatttct
     3781 ttttaggaac agacggtttg ggacgtgatg tattaagccg cttatttatg ggaatgagaa
     3841 tctcgttgct gatcgcattt attgctgcat tactagatgt aacgattggt gtagcttacg
     3901 ggttggtttc tggtttgtta ggcggacgtg tcgataacgt gatgcaacgt tttttggaaa
     3961 tcttatcagg aattccaaac ctcgttgtca tgattttgat gttggtcgtt tttgaaccag
     4021 gaattttttc aatcgtggct gctatggcca tcacaaactg gataccaatg gcacgtatcg
     4081 ttcgtgcaca aacaatgaaa ttaaaagatc aagaatatgt tttagctgga ttgacattag
     4141 gtgaatcaag aatgaaaatt gcattcaaac atattttgcc gaatatctct agtgtcatta
     4201 ttattcaaat gatgtttagt attccatctg ctattttctt cgaagccttt ttaagcttta
     4261 tcggtttagg tcttacgcct ccgtcagctt cattaggaac gatgttgagc gaagggtaca
     4321 agacattcct gtatctgcct tatctattat ggattccggc agtaacttta tcggttatca
     4381 tgattggctt taacttactt gctgatggat tgcgtgatgc ctttgatcct aaaatgaaag
     4441 agtgaagacg atgacgaaaa ttttagaagt gaaagactta gaaatctctt ttgatacgta
     4501 tgctggaaag gtacgagcga ttcgcggtgt caattttcat ttgaataaag gagaaacatt
     4561 ggcgatcgtt ggggaatctg gaagtggaaa atcagtgacg accagaagca tcatgcgctt
     4621 gctgtcaagc aacgccaata tagatgctgg tcaaatcctc tttaaaggta acgatatcgt
     4681 tggaaaatca gaaagagaga tgcaaaaaat ccgtggtaaa gaaatagcga tgattttcca
     4741 agatccaatg acctctttag atccgacgat gcccattggg aagcaagtcg ctgagtccct
     4801 tagaaagcat aataaagttt caaaaaaaga gggacaaaaa gctgcattag aattgcttaa
     4861 attagttgga atacccgaag ctgagaaacg tatcaacagt tatccgcatc agttctcagg
     4921 aggtcagcgt caacggatcg tgatcgcgat tgcactggta tgttatccgg aaatcctgat
     4981 tgctgatgaa cctacaacag cgcttgatgt gactattcaa gcacagattt tggagctgct
     5041 gaaagaaatt cagacaaaaa tcgatacatc aattatcttt atcactcatg accttggtgt
     5101 agtagcgaat gtcgctgatc gtgtcgctgt catgtatgga ggaagaatcg ttgaagttgg
     5161 aacatcggaa gaaattttct acaacccgca acatccctat acttggggac tgcttggttc
     5221 aatgccgaca ttagatagtg cgaacgatcg attgtatgct attcctggtt ctccaccgga
     5281 tttattgaac ccgccaaaag gagacgcatt ctatccaaga aatgaattcg cgatgaaaat
     5341 cgatgcagaa caagaaccac cattttttga actatcaaaa acacacaagg cagcaacttg
     5401 gctacttgct ccgcaggcac ccaaagtgac accgccagaa gaaatccaac gtcgctgggc
     5461 tatctttaaa gagaaacaaa aacatactta cggtcaagga ggaattgctg atgccaaata
     5521 aactacttga agttaaagga ttgaaacagt atttcaatgt aggaaaaaag aatgaagtac
     5581 atgctgtaaa tgacatcagc tttcacattt atgaaggaga aacattcggt ttagttggag
     5641 aatctggaag cggaaaatcc actactggcc gtacgatcat tcgcttgaat gaacctactg
     5701 atggtgagat attattcgac ggtcaagata taacgaagat caaagataaa aaaggtttga
     5761 cgaaattccg gcatgatgtt cagatgatct ttcaagatcc atacgcttcg ttgaatcctc
     5821 gtatgaaagt cagagatatc attgccgaag gaattgatgt taatggacta gctaaatcat
     5881 ctgaagagcg tgcaaaaaaa gtcgatgatc tattgagaac tgttggattg aatccaagcc
     5941 acggtactcg ttatcctcat gaattttcag gtgggcaacg ccagcgtatt ggtattgcac
     6001 gagcattggc agtaaaaccg cgttttatca tttgtgatga accaatttct gcactagatg
     6061 tgtcgatcca agcccaagtg gtcaatttgt tgcaagatct ccaaaaagaa catcaattga
     6121 cctatctatt tattgcacat gatttgtcga tggttaaaca tattagtgac cgaatcggtg
     6181 taatgcataa cggcttgtta ttagagatgg gaacaagtga tgaaatctat aatcacggtg
     6241 ttcatcctta tacagaaagt ttgttatctg ctattcctct accagatcca gaccatgaga
     6301 gaaaacgcag aagaatcaaa tatcaacctg aaccagatga cggacaagta cgtcaacttc
     6361 gtgaaatcgc accagaacat tttgtctatg caactgagca ggaagtccca tattacgcaa
     6421 aaaaactaaa acgacaaaag gaatctcttc tggttgctaa ctaggaggga catagatgct
     6481 aaaagctttt aaattccgta tgtatccgac agaagaacaa aaacagcaat tgattcgtac
     6541 ttttggatgt gctcgattta cctataacca tttgctgaaa aagcggcaga aaagttggca
     6601 acaaacagga gtagccaatt tttcgctcac acccgctaca ttaaaaaaag aatacccatt
     6661 cttaaaagaa gtagacagtc ttgctttagc aaatgcacag cttaatttgg atcgggcttt
     6721 tcgcaattat ttcaagggac gtgccagctt cccaaagctt aaaacgaaaa aaagtatgtg
     6781 gcaatcttat acgaccaaca accaaacccg tacgatctat ctggaaaatg gctacttaaa
     6841 gttaccaaaa caaaaagaac taatcaagat aaatcagcat cggccagttg aaggatcgat
     6901 tcgctccgct acgatttctg ctcgatataa tgaagaattt tatgtcgcac tactttgtga
     6961 tgtttcgcca gtaaaaaaag aatctttagc taaatggatc gggatcgcct atcatccgaa
     7021 gacattgatc caaacatctc gacctctaga agtaacttta ccaaaatttc accagacaga
     7081 agaaaagctg caacatgcac agcggaaatt gaatgtgaaa gtccgctccg ctcaccatag
     7141 aaagatcagg ttagatcagg caagcaatta tcagaaacaa aagagaaaag taatggatct
     7201 ttatctgaaa caaaagaacc agcgagaaga ttatcttgaa caattatctg ggaaattggt
     7261 caaacaatat gactacttat ttgtagaatc ttttccaaaa gaagaggcac atgctgattt
     7321 ttctattcac gactggcata aattaataac aaaattgcgt tataagtccc aatggtataa
     7381 taaaaaattt cttttgatca ataccgacgg agcagaagaa agcaattccg taagaaagag
     7441 ccaagtagta gaaaaaatgg gcagacattc ggttatcaag ggataaaaaa tgaatgaaac
     7501 tgataggagc gttagggtta gccttgttaa taaaaagtct taatgacttt tgtttctagg
     7561 aatttttctt ttgaagaaaa gctcactaat tatgacaaac caataaaaca atagcagaaa
     7621 aagttcgtac gagctttttc tgctattgtt aattttttat tcagaaagtt tacgaataca
     7681 tcaaaattct gaaacaaaaa acgtaactca caaagagttg tttttgcgtt ttttcttgaa
     7741 tgattaggtc tgaatctttt gctcacaacc ttattcatgg tgccccggct tgagctgata
     7801 gatttttgaa ggacggccga ttcctacagg acgttcaccg atctcatcga aatattggag
     7861 catagctttc ttaaaattgg aatgatcgat cgttttataa tcgatcccta agaatttagc
     7921 aaatactttt cgagcttccg taatcgtgaa atctttacct aaaacttgta gaacttgcgg
     7981 ctcgtgttcc attttattga ctacacggtt gaatgctttc aagatgattt gactatggtc
     8041 aaaagccaaa gtatctttgc cagaagactc tccagtgact aaatcaagcg agatagccac
     8101 ttctccgcta gataaatgga tcttgttact atgacgttct agtgtgaacc agcgtacttc
     8161 cttggcatca tctccggcga ttagcggttc ttctccaata aaggctaagt agctgactgt
     8221 gacgacccag cctcgcggat ctcgattagg cgtactgaat gtatgcagtt gctcaatatt
     8281 ttcttttgaa ataaccacac cagtttcttc ctttgtttct cttaagacgc tttctccagt
     8341 tgactcatcc ttttggacaa agccaccagg caatgcccat gaatttcgat aaggatgccc
     8401 ttttctttgg atcaacaaaa ctttcagctg atcttcttct ttgttatagc acatcagtac
     8461 gatatcgaca gtcaaagagg gcttgtcata ttctggacgt tcctgttttt gataccagtt
     8521 aagaaattct tcttcacttg ctttatgttc ataatataat ttttcttctt ctttagaagc
     8581 aaaacggttc atctgaccac ctccattgac agtaaaagta ctttttacct tattgtagca
     8641 gactctgaaa aaaaaccaag gatttacttg aaaaatctag gttatcattt aaatatgaaa
     8701 aataaatgga agtatgagat tgaataaaaa gaaaagcaga taaaacggca atactttata
     8761 ccgctcttca cgaatggcaa agaagccaca aataacgata tatacgtcaa tgataaaacg
     8821 caaaatccaa gctgctgtca taaaactgtt caaatgccca tggaggttaa aataaccata
     8881 catacgaata taaaaatagc tgaatattaa atgtgctaat gaaagaaaag caatactaag
     8941 tgtaaaaaaa agatgtttct tctgcatgat tgttccagtc ccttactaag atagatagtc
     9001 tttattatac cacgtgtgag gggagaaata aaaagccgtt ttttagtaga tatgaaacaa
     9061 aacaaaaacc cgcatttatt caacctattc atccttttaa aggatagatt gaacgtagat
     9121 agaagtcgtt tatccagtct ttttcatttt gaaaaaaagc taacagcatg ctttttttat
     9181 ggtatactag caaggaaacg aattcgcatc atgcgataaa ggaggaagag ccccgtggca
     9241 gaaaaggaaa ctttttatat cactacgcca atctattatc caagcggcaa acttcatatc
     9301 ggcaactcgt atactacgat tgcatgtgac gcaattgctc gttataaacg gttgatgggc
     9361 tttgatgtgt tttatctcac tggagtggat gaacatggtc aaaaaatcga aacaaaagca
     9421 gaagaactag gtgtaaaacc gcaagaatat gtagataaaa tggcggctga tgtcaagaaa
     9481 ttatggaaaa cgcttgatat cagttatgat aaattcattc gcacgacaga tgattaccat
     9541 aaagcagctg ttcaaaaaat atttgatcgt ttattagaac agggagatat ttacttaggt
     9601 gaatatgaag gctggtactc tgtttctgac gaagaattct ttacagaaac acaacttgca
     9661 gaagtgtaca aagatgacga aggtaacgtg atcggtggta aagcgccaag tggacacgaa
     9721 gtagaattgg taaaagaaga atcatacttc ttccgcatga gcaaatacgc agaccgtcta
     9781 ttggaatact atgaagaaca tcccgaattc atccagccag aatctcgtaa aaacgaaatg
     9841 atcaacaact ttatcaaacc aggattagag gatcttgcag tttcacgaac aacttttact
     9901 tggggagtac cagtcaagag tgatccgaaa catgtggtgt atgtatggat cgatgcatta
     9961 tccaattata ttactgcact aggatatggc tccgaagatg aaagtctatt cgaaaaatac
    10021 tggcctgcag atgttcagat ggtcggtaaa gaaatcgttc gctttcatac gatctattgg
    10081 ccaatcatgc tgatggccct tgatttgcct ctacctaaaa aagtatttgg gcatggctgg
    10141 ctattgatga aagacggaaa aatgtctaaa tcaaaaggaa atgtcgttta tcctgaaatg
    10201 cttgtggaac gttatggttt agatgcactc cgttattatt tgcttcgtgc tgttccgttt
    10261 gggtcagatg gtgtctttac gccagaagat tttgtttccc gtgtcaatta tgatctggca
    10321 aatgatctag ggaacttatt gaatcgaacg attgctatga tcaacaaata ttgtgatgga
    10381 ctcgttcctg actatgcctc acttgtcact ccatttgata gtgaactgtc tacgacggct
    10441 gctaacgttg tcggacgtta ccatgatgca atggaaaaaa tggaattcaa tacagcattg
    10501 gctgaaatct gggtgctgat ttctcgtgca aacaaataca ttgatgaaac agaaccatgg
    10561 gtattagcaa aagacgaaga aaagaaagct gaattgaata gtgtcatgat ccatttagct
    10621 gaatctttgc gtatcgcagc gatattactt cagccaatca tgacagaaac gccagagaag
    10681 atcttcaatc aactaggatt ggactctgaa acaatgaatc ttgaaggatt acactttggc
    10741 gaatttcctt caggaacaaa agtagttgca aaaggtacac caatcttccc acgtttagat
    10801 atggaagaag aagttgcttt tattcaagaa aaaatgtctg aaggtactca aacaaacgaa
    10861 gatacagtca aatgggatcc agaagaaaca gaacttgttt caacgaaaga aaaacaaatc
    10921 aaatttgatg tatttgaaaa agtagaacta aaagtagcag aagtcatcaa ctgtcaaaaa
    10981 gtagaagggg cagataagtt gctgcaattc cgactagatg ctggagacag ccaagaccgt
    11041 caaatcttgt caggaatcgc tgaattttat cctgatccaa gcgaattgat cgggaaaaaa
    11101 gtcgtcattg tagcaaatct gaaaccacga aagatgcgtg gacaaatcag tcaaggaatg
    11161 atcctttctg cagaagcacc agatggctct ttacaagtaa tcgaagcacc aaaatccatg
    11221 ccaaatggct cagaaatcgc atagaaattc aaagggggta tgacactagt tgtgtcatac
    11281 cccctttttc cgaaatttga gaagcaattt tcgtaaattc cttcttatta cttgaagcca
    11341 atcatataat acagaaacag agaactatcc aaaataaatc ctagaaaaag aagtacgagc
    11401 ttcgctgatt tttgttaatt tagaataata ctaataggaa tcgtaaaaac agaaaaaaag
    11461 cataatgata aagggtcggg cagattttaa ttgattcatc tggtactctt ttttattgtc
    11521 cttacattca taaagtttga atgcaatgac tttattacat ctatatttat atctaacagt
    11581 agcgttgatg tgttaattat aagttctatc actttatgtt caattagttt gtgctcttat
    11641 atgtgtgatt gaaaatatag ataaaaaaac aatcatcggc tttgacttcg atgattgttt
    11701 tctttatttt gtaaaaatcc tatcacttga ttttatggta accttttatt tttgtcttca
    11761 aacggcttgg taagagagca gtaagcagtg caaatgggat cgaaaagaca taccagaaaa
    11821 tcgtacgtcc gataccataa tgttgataga gctttgtcaa catcacgtgt aacaagatca
    11881 accctaaaag caaggagcca gctataaacc aatgattatc ccaatgcatg acttcactaa
    11941 gtgccatcac tccaaaagga tagaaataaa aatagatccc gactaaggtc atccgccagt
    12001 tctttgtaaa tgttccgata ttcaataaaa agaaaatcgc tgaaagcaaa ataccgatag
    12061 gcggaaaaag cccaaccaaa aaggaataca acatccccca caagatcatc acaggacctt
    12121 tgatcaatgc aacgattgcg atgaacaaag tcagcaatat tagtttttgt gataacgttg
    12181 caacagtcat taatccaaat aaaattaatg tgaaccaatg ccaatgggac tgctgttgtt
    12241 ctttacggga aaaatcgacc cggttggata aataatctgc taatttcgga taagaacgct
    12301 taaaatccat aaactgttcc tccttcgtgg aaaaggtagg tttagtatac gaaaaataaa
    12361 aaagaaatac atccgtctta agagggagtt tttcactgaa agtggagaaa aaagaatggt
    12421 aaattaaaat attctcagtt atactgaaaa ttataccaaa tttcaaagaa gaaagaggat
    12481 gggaatgaaa ggcaaactaa aacgagaaat caatctgttt ggcgcattag ctaccgttat
    12541 gggaaccgtg atcggtgcag gcgtcttctt caaaactgct gctgttactg ctagtactca
    12601 gtctacaagt ttgacattgc tagcttggct tttgggtggt ttcttaacga tctgtgctgg
    12661 attgacagtg gctgaattag ctacagcaat cccggaaact ggtggagctg taaaatatat
    12721 tgaagctgcg tatggaaaat tgcccagctt tttattagga tgggcgcaaa gcttgattta
    12781 ctttcctgct aatattgctg cattatcgat tatctttgcg acacaattga cgaacttatt
    12841 acaattatct accgattatc ttttgttgat tgcagtgatc accgctgttt ctgtgacagg
    12901 gttgaatttg ttagggacaa aagtcggtgc ttctgtacaa tcagtgacgt tgattgttaa
    12961 attaatacca attgctgtga ttgtcatatg gggattattg accccaggac aaggaactgt
    13021 ccagttattt ccaatcgaag ctggaaaaga tgttactttt gtcgaaggat tgagcagtgc
    13081 gttgttagca acgttgtttg cttatgacgg ctggttaggt gtcggtgcaa tggcagggga
    13141 aatgaaacgg ccggaaaaag atttgcctaa agcaattatt cttggtttga gttttgtaac
    13201 agtcgtttat ctattgatca attttgtttt tttgaaaact ttgccgattg atcatcttgc
    13261 cggtaatttg aatgcagctt ctgaagcatc agacgtcatt tttggaggaa tcggtggaaa
    13321 gctggtcact attgggatct tgatctcggt atacggtgca ttgaacggtt atacactaac
    13381 tgggatccgc gtgccttatg cgatggcttt agaagacgag ctacctttca gtaaacagct
    13441 gacaaagctt tcaaagaagt ttacggttcc ttatgttcct gcggttttcc agttagcagt
    13501 agcttgtatt atgatgagcc ttggttcttt cgacttttta acagacatgt tgatttttgt
    13561 gatgtggcta ttcagtttac tgatttttat cggtgtcttt attttaagaa aaaaagcgcc
    13621 ggaattgcca cgtccatata aagtaccact ttatccaatc gttccgatta ttgcgattct
    13681 cggtgctatt ttcattttag gtatgacgat gatgacgcaa acgaaattag cattgatcgg
    13741 tataggtgtt accttgatag gtatcccagt ctattatcaa aaaaagaaaa aacgctcaga
    13801 agagtaaaat atttcaacaa cagacagaaa aagtacgaac taggtcctct agatcttcgt
    13861 gctttttcta tttcaataaa acaagttctt ctattttgat ttttgctact tctgcaagta
    13921 gtgcttatgt gctaaagtaa gaatgaaaag gagagataaa catgatattt gattctcata
    13981 cccatttaaa tgctgaacag ttcaatgaag atattccaga aacgattcag cgagcacaag
    14041 aaatgggggt aacgaaaatg gcggtcgtgg gcttcgatac gccaacgatt gaaaagtctt
    14101 tgcaattaag ccatgactat ccaaatatat acagtattat cggctggcat ccgacagagg
    14161 ctggcagtta tacgaaagaa atcgaaaata aattacaaga acaattgact ttaccaaagg
    14221 ttgtagcatt aggggaaatt ggcttggatt atcattggat ggaagacccg aaagaagtcc
    14281 aagataaagt atttcgcaga cagattgcta tcgcaaaaga aatgaaccta ccaatcagta
    14341 ttcatactag agaagcactt gaagacacgt atcaaatcct aaaagaagaa gatgttcgag
    14401 atatcggtgg aatcatgcat agtttcagtg gtgattatga atgggcaaaa cgatttcttg
    14461 acttagggat gcatatttca tttagcggtg tcgtcacttt caaaaaagca ttagacgtcc
    14521 aagaggctgc agcaaatgta ccaatcgaac gattacttgt ggaaacagat gccccttatc
    14581 tggcaccagt tccttttaga ggaaagcgaa atgaaccagg ctatactcgt tatacagtag
    14641 aaaagattgc tgaacttcgg aatcttccga cagaagaagt ggctgcccaa acatggacaa
    14701 atgcgcaccg attatttggt ctaagcgaac atggataaga tgaagatcca agagattata
    14761 gtcgttgaag gaaaagacga tacaagaagg ctgcgggaag tagttgatgc agatacgata
    14821 gaaacaatag ggtctgcaat caatgaagag atcctgatgc aaattgaaca tgcccaagag
    14881 actcgtggag tgatcgtttt taccgatcct gatttttcag gagaaaaaat aagaaaaatc
    14941 attatggaag ctgttcctca ggcaaaacat gcttttttgc cgcgcacaca agctaaacca
    15001 aagaaaaagg gaagccttgg tgtcgagcat gcaagtgatg ctgctatttt agaagcattg
    15061 aaaaaggtcg tgacgccaga catttcccaa acggctgttt ctgaaatcac tagacaagac
    15121 cttttagact atggtttaat agctggggca caagcaaaag aaaaacgaga aaaactaggt
    15181 gacgagttgc gcatcggtta cacgaacggc aaacaattgg aaaaacgttt gaagatgttt
    15241 cgtattacgc cgaaagaact cgcccaagca atgaaaatag tggaggaaca acatgagtga
    15301 atatcgtgaa attgcgacac cctctagaac aaaagagatt ttattgaaac atggtttttc
    15361 atttaaaaaa agtttaggac aaaattttct gactgaacca aatattttaa ggaaaatcgt
    15421 agaaactgcg caaatagatg aacatacgaa cgtgatcgaa gttggaccag gaatcggtgc
    15481 attgacggaa caattagcca agcatgcaaa acaagtcgta gcatttgaga tcgatgatcg
    15541 tttgatccct gtattggctg atacgatgca accctatgac aatgtgacta ttgtacatca
    15601 agatatttta aagaccgatt tgtcaacagc tgttagagaa acatttcatg aggagcttcc
    15661 gttaaaagtc gtagcgaatt taccttacta tattacgaca ccgatcatga tgcattttct
    15721 tgaatcagat ttggttgtgg atgaactagt cgtcatgatg caaaaagaag tagctgatcg
    15781 tatctctgct gaaccaggaa cgaaagctta tggttcatta tcgattgctg ttcaatatta
    15841 tatggaagcc agtttagcat tcatcgtacc aaaaacagta tttgtccctc agccaaatgt
    15901 agattcagcg attttgaaac tgacaagaag agatataccg gcagtcgaag tgacagacga
    15961 aaaagcattt ttccgattga caaaagcggc atttcagcaa agaagaaaaa cgctttggaa
    16021 taacttgcag cattcgtatg gcaaagatga ccagacaaaa gcatggttag caaaaagctt
    16081 ggaaacagct ggaatcgatc caaaacgtcg tggggagact ttgtcattac aagaattcgc
    16141 cgcattaagc aatgcgatgt cagaaaatat gcagtaaaaa aagaggttgt gacagaagtt
    16201 gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa acaaaaatag ttcctcatgt
    16261 ttttcgtttg tttgggctta ttaccgcaga tgcaagcttt tgaacaccgt ttaagaaaga
    16321 ggttgtgggc ctgccgttta actctaagtc acaaggaaca atttcaaaaa acagcttctc
    16381 atgtttttga gttagttggt cttattactt gatgcaagct tttgaccact attatgccga
    16441 acaaggagat gtgacacaaa ttttgtcaca tctcctattt ttgtttcttg atcaaaaaat
    16501 tcttatactt gatactcaca ctcattttgt atggatttag aaaagaatat gtgtcttgac
    16561 agttattagt aagtgagtta tactaagtcg acatttatgt gtcaagacat attaggagag
    16621 agaaaaaatg agaaaaaatt cagttcgaaa actaacgatt tctgctttat tgattgggat
    16681 gggggtcatt atcccaatgg tcatgcctaa aatcatgatt ccaccagctt cctttacttt
    16741 ggcgtctcat gtgccattat ttattgcgat gttttttaca ccaggagttg cagtggctgt
    16801 tgcgctaggt acgacatttg gtttcttttt aacaacgccg gttatcatcg cattgcgagc
    16861 attgtcacat cttgtgtttg cgttgattgg ggcttggtac ttgcaaaagc atccgagtat
    16921 cgttttaaaa aatggacagt ttacttttgc taattggcgt ttccaagggt tcaattttgt
    16981 gatcggtgtg attcattctt tagcagaaat gctagtagtc agcatctttt actttattgg
    17041 taatatgcct gaaacatatt attctcaagg atatttttat acagtattca tcttgatggg
    17101 gattggtggg cttatccaca gtttagttga ttataatatt gcttatttta tagcaggaac
    17161 actcagcaaa tattttgata tccccgtatt tacggcagca aaaaaagaaa atcggaaaga
    17221 gtcgattcaa gggtacgcga agaaaacgac atattagaca tgatctctca aaaaaaaaac
    17281 tctcatctag taatggataa taaatcctct aagatgagag ttttttgtcc taaaaagagc
    17341 tgcaccaaca tcttctggca cagctctaac agggggcaat ttatggaagt ttgatgactt
    17401 gttctgtttc tttatcaaag aagtggcctt tgctgatgtt gaaggcaagg tcgactattt
    17461 cgcctggttt atggaaatct cttgcatcta cttttgagat gaactcagta gaaccagttt
    17521 ttgtgtaaag catcgtttca gctccaagta attcggaaac gacaacttct gatttcacta
    17581 cggcttcagg tgaagcttca agggctactt gttcactgtg gatgtcttct ggacgaatac
    17641 cgaagataac ttcttttcct tcataacctt tttcaactaa tactttgttt tttccttcag
    17701 gaatacgaag cttaagccca tgtccatctg tgataacacc atttttcaat gtcacattaa
    17761 agaagttcat ggcaggagat ccaataaagc cggcaacgaa catattgacg ggtgtatcat
    17821 aaacttcttt cggtgtaccg atttgttgga taaatccgtc tttcatgata acgattcggt
    17881 cagccatagt cattgcttct gtctgatcgt gagtaacata gatggtcgtt gtttcaagac
    17941 gctggtgaag tttggcaatc tcagcacgca tggctacacg taatttagca tctaaatttg
    18001 ataatggctc atccattaag aagacttttg catcccgaac gattgcccgt cccaatgcca
    18061 cacgttggcg ttgtccacca gataaagcag ctggttttcg tttcaagtat tctgtcagac
    18121 ctaagatctc tgctgcattg tccacacgtt ttttgatgtc tgctttatca tatttacgta
    18181 atttcaagcc aaaagccata ttatcaaaaa cagtcatatg aggatacaat gcgtagtttt
    18241 ggaaaaccat ggcaatatca cggtctttag gtgccacgtc attcatgact tttccgccga
    18301 tatttagttc tccttcagag atatcttcca gtcccgcgat cattcgcaaa gtagttgact
    18361 ttccacaacc ggaaggacca acaaaaacga taaattcacg gtctttgatt gatagattaa
    18421 aatcagttac agaataattt tctgcattgt catatttttt atatacgttt ttcagagcca
    18481 tttctaccat aatacgttcc acactttctt ttttagtttt attaactatt taaagtataa
    18541 atgaaagcgt taactaactt caatgtcatg ttgaacaaga attttttctt ttttttgtca
    18601 atgtgctagt tttaagcttt aataaatatc cataagaaat aaaaactgat acactggagt
    18661 aaataagtat gttaacaata tcaaaaggag tgtctcttat gaaaatcgct ttgatcgctc
    18721 atgaccgaaa aaaacctatg atggtgaaat tagcaacagc gtataaaaca atattggaaa
    18781 aacatgaact ttttgctacc gggacgactg ggcagaggat cacggaagca accggcttgc
    18841 cgatccatcg gtttaaatcc ggaccgttag gcggggatca gcaaattgga gccatgattt
    18901 cggaggatca gttagatttg gtgatttttc ttcgagaccc gctggctgca cagccccatg
    18961 aaccagatgt aacagcactt atccgtttat ctgatgtcta tgagattccg ttagctacga
    19021 atatcggaac agctgaggtg ctactaagag gactggaagc cggcttccta gattttcgaa
    19081 gaatcgtcca tgaaatagac aagcatccac tttcattttg atggataagc gtatggaaaa
    19141 ataacgttta atgttcgcct atatgtagct ataaaagcta aacaaactga taatatgcga
    19201 tataatacga acgtattgga taatataaac aataatatta gtttttcgta tttgcagtaa
    19261 atgtgaaaat atgctatagt ttctgtggga aaagatccca aaaataatac agagtagaaa
    19321 ataaagcgtt aagtgctaag aggatgggat gttgcctctt ggacgaagga cgtaatgttc
    19381 gcggttttat tttcgcattc gctgcatgat acgatgtagc agctcttaaa ggagatgcta
    19441 aaaatgaaga aacaccggtt agacgcacgt atgattgcta ttatgggctt attgattgca
    19501 ttgatggtca ctttgtcccg actggtagca atcgagaccc catttattaa aatcagtgtc
    19561 acatttattc cacaagtgat catgggcatt ctttttggtc ctttttggtc agggataggc
    19621 gcagttttag ctgatttagt aggaatggcc ctcttctcga aatctgcatt ctttattgga
    19681 tttacattga atgcatttat tgaaggagca atctacggat tctttttcta tcgaaaagag
    19741 atcacttgga aaaatgccat tctggctacg cttagtgtca cgctgatcat caacttattt
    19801 ttgacaccat tatggcttgc gttgatgtac catgtgccat tgttcagctg ggtcgtttgg
    19861 gcgccccgcc tgttaaaaac agtaatatgg ttaccgattc aatcaattgc catttattac
    19921 gtaggacgta gtattcctta caaaaaaatt ttaagaagtt tagcgatcca cgctaaataa
    19981 aaaacaagca gtcttcccat cccagaagac tgcttgtttt tattgtgctg tgaattgtgc
    20041 ttgatagagc cgtcggtaat aaccatcttt ttgaagcagc tcatcatggg tgcccatttc
    20101 gacaatagct ccctgatcca tcactaatat ctggtccgca tttttgattg tggacaggcg
    20161 atgggcaatc acaaaactgg tttttccttc catcattgct aagaaggctt gttggatttt
    20221 tttctctgtc aatgtatcga ctgagctggt agcttcatct aagatcaaca tagggggatt
    20281 actgatcatc gttcgagcaa tcgtcaacag ttggcgttgt ccatctgata tctttaaccc
    20341 ttgaccgcca atcttagtat ctaatttttc cggcaaacgt tctacaaatt catacatata
    20401 agaggctttt agggcatcat tgatttctgc gtcacttgct tccggattcc caaaacgaag
    20461 attttctcgc aatgtactgt caaatagcca agtatcttgt aacaccattc caaaactttt
    20521 acgtaatgta tcacgttgga tagagcggat gtcatggtca tcgactgtaa ttgttccttt
    20581 tgttgtgtca taaaaacgca tcagcaaatt aacaagtgtg gattttccgg cccctgtttt
    20641 tcctactata gcaatggttt gacctggata agcagtaaaa ttgaaatctt cgatcaaacg
    20701 ctgcttgggg tcataagaaa aagaaacatg atcaaaagag acttttcctt tgatattttt
    20761 gggttccaag gcataggcat ctggcaaatc aggcttttct tctggctgat cgatcaaatc
    20821 aaatgctcgt tctagaccag aaaaagcggt ttgcagttgt gtcgtgattc cagaaagttc
    20881 gataaatggt ttagaaaact gacttgagta gatcgtaaag ctggaaatca caccaacagt
    20941 gattgacgaa ccactcttca atgccaatag gccgccaact aaaccaatcg ataaataagc
    21001 aaggtgatct acaaaacgag aagacgggtt tgtcaaggaa gaagaaaatt gtgcccgttg
    21061 tcctttttca tatagatcag catttagcag ttcaaattgc tgttgactag cttcttcttg
    21121 ctgaaaagct ttcacgattt tctggttacc gattcgttcg gtcacaaagc ccgagatatc
    21181 cccaataatc ctttgctgtc tatcgaaatt tgtttgtgaa gcacgagcaa cgatccaact
    21241 cacaaggaaa ataattggtg tagaacaaag aacgaccaat gtcagaagtg gacttagacg
    21301 catcataaaa ataaacgaaa gaatgatgat tgccactcca gaaaataatt gattgaaggc
    21361 cgcagaaatt gcaatggaaa tattgtccat atcatttgta aatcgactga cgatatttcc
    21421 gtgggagttt tgatcataat aacgaagtgg caatcgattc agatgagcaa atgcatcttt
    21481 tcttaatttt gcaacggata agtaagctaa ccgattgctt aacacttgga tgagccattg
    21541 actgactacg ttgattaaaa cgataccacc gaatagaata agtaaatgga acagtcgatt
    21601 gaagcggacc tgtccttctc caatcatttg atcgatactt tgaccaattt gtaacgtcat
    21661 cacaactgtt gcaatcccat tgatgattcc tagtatcaca gctagccaaa tgtcttttgc
    21721 ataggcagta aggtaaggaa tgaatcggcg gagcgtctgc aaggataatt tttttacttt
    21781 cataactatt cttcctcctg tgatgcgacg atttcctgat attctgctga ttgagcaagt
    21841 aattcttcat gggtaccctg agcagcaatc ttaccttgat ccatcactaa gatatgatgt
    21901 gcttcttgaa tagagcggac acgttgggag ataataatca ctgtactgcc aagataagtc
    21961 tgtagcgcct tacgcaaatc caagtctgtt tgataatcca acgcacttaa agagtcatct
    22021 aaaatcagta atgctggctt ggcaatcaaa gctcttgcaa tcgtcagtcg ctgtttttgt
    22081 ccgccagaga aatttttccc attttccatg acttttgtat ctaaaccatt tggaagctga
    22141 cggacaaatt cttctgcctg agcgattttc agagcttccc aacattcttt ttctgtggcg
    22201 tctttcttac cccattgaag gttttcacga atagtcccgg taaatagtac agaagtttgg
    22261 ggaacaagag caatttgctg acggagatga tccagctgcc aagaacgaac atccattccg
    22321 tccattataa ctgtaccgga actgacatca tagaaacgcg gaatcaattg tgtcaaagtc
    22381 gttttcccgc ttccggttgg accaatgatt ccaaggactg tatttcgctt cagctgaaat
    22441 gtaatatttt ggagagaaag accagaatca ggagtataac ggaagtcaac atggtcaaaa
    22501 gcgataattg cttcagaaga aaaatcggga gtagtactga cctcagcttc aagaatcgaa
    22561 ttttctgtgt ctagcacctc tttcacccga tttcctgaag cttcggcacg tgtgaagatc
    22621 acgacgaggt ttgaaacaac gatcagtgcc aaaagcattt gattcatata attgatcaaa
    22681 gcaagaactt gtccttgttg caagctacca atatttactt tgatcccgcc aactgtcagc
    22741 aaacagatga tcccgacatt catgatcaag gttgtagcag gtgataatag ggcagagata
    22801 ttggaaacac gtaaataatt gttcgctaga tcatttgtgc ttttatcgaa cttctctgtt
    22861 tctttttttg tctgcgcaaa tgcgcggatg acacgaacac cgctaagatt ctgactaacg
    22921 tgttcattga gctgatctag tttttcttgc actttttggt agagaggaac ggtttttttg
    22981 atgataaaaa ataaaatgat tgagaaaata ggcaataatg ctaagaaaaa cagacctact
    23041 tcccagtcga tcacaaaagc catgaccact gacccgatac ttaaaaacgg tgctctgatc
    23101 aataaacgaa tgaccattgc taaagctagc tgaagctgat tgatgtcgtt tgtcattcgg
    23161 gtgatcaagg tatctgttcc aaaatgattc aactcgttgt gagagaaagt attgattttt
    23221 ttgattagct gattacgtaa ctctgtacca aatccttgtg aagctactga agcatagtat
    23281 tggcaaatga tagcacaaat cagaccaatc acagacatag cgaccatcca taagcccatt
    23341 tcaatgattt ttcctcggtc attcattttt agtccattat cgatcaagga agccatcatt
    23401 aaaggcagga caagttcgaa gacagcttca agaaatttga agaacgggcc caaaatgatt
    23461 tgcttacgat agtcttttgc ataacgtaat aactgaatca tatgattcct cctattattt
    23521 atttgtccac aattgaaaaa acaagtacta ccacattgta gcttaggaaa tttagaatga
    23581 aaagagaaca agccttttca taaatgaaag ttttattatg aagaagcttt agaaattgaa
    23641 tagactattt tttttaaaaa aaagaaaatg agaaaacatg ccagtctctt cattcatagg
    23701 aacgtctatt ttacttaatt tttctataaa tgaattctgc ataaaaaata tatcaagtaa
    23761 atgtttatag atgaaactct atttacttct tttttaattt gttcttgcaa tcttttttgc
    23821 tacgtaattt ttgtaaaaaa gtgggttgag agaaatctaa ttgattttca aagaaggagt
    23881 atgaaaatga gaaaaatatt tattcgttta ttgtgggtac tatcttagag gaataaataa
    23941 tagtggagaa aactatggtt tggcgcagat tctatcaggt ttgatggaac gaagacaacc
    24001 tcccgacatc aagtcaaaag ccacttgaga ttttgatctg aaaataaaaa aagaaaacaa
    24061 ggtaggaaca tcaatgtttc taccttgttt tcgtaatcaa tgggaaaaaa ctaagagtgg
    24121 tgtacgtaat caataaaaag gatggtgaca acagtacctc tttactctct gaaagcatca
    24181 taactcgttt ttcctcatta tgccaataaa ttgttgttat accacatata aggatttgta
    24241 atagctaaaa acagacagga aagttgaaat ctgtgaatct tattttgtat ggaaggattt
    24301 atagaacgca aaaatcaaga taaagatgaa taaaaatcct gtttcggcta tatattgcgt
    24361 atctacgcca ataaaacgag tttgttctgt catagccata taaagcaaag gcaaaaatac
    24421 aactacagcg agataagatc cgatgatttc tcgaaaagtt ttccaggaag tatgtttcct
    24481 gtttttatat ttatccgatt tcattgaata gtcatagcct ccttattctt tcatatgttg
    24541 aaattccagt ataaaaactg gaaggaactg tacgtttttt agaataaaaa ttataaggga
    24601 taagtaggct gctgtctata ataagatata tttttcaatt ctttattaaa gattttattg
    24661 acaaaatgaa tccgttttct atgatggagg aggggtgaat aagttgttga agaaggaaat
    24721 tttatgttac ttagagaacc agacagcctt tttcgattta gaacatatga acgaggtctt
    24781 tacagcacaa aggttagctg atcattttgg ggtaaaaaga aacacagtca gtcattattt
    24841 gaaccagtta aatgatgagc aactactagt caaaatcaat tctcgaccag tgatttattt
    24901 ccacaaagaa gcttttgaaa aacaattttt taagttacgc acgaattttt atttttctat
    24961 cgatgatctc aaagaggaac agcctttttt cgcgcaacca aaagacttat tctcttttat
    25021 gatcggatac gacgccagtt tgaaagaaag tatcgaacaa atcaaaacag ctctttacta
    25081 tccagatggc ggattaccac ttttgattac aggcgaaagt ggcacaggta aaagttattt
    25141 agttaatttg gtctatcagt attgtctgct tcatgatctg ctagaagatt ctgcaccatt
    25201 catcactttt aattgtgcac aatatgcaga taatcctgaa cttttgacta gcaatttgtt
    25261 tggacatgtt aagggagcgt acactggtgc agaagaaaat aaaaaagggg cttttgaagc
    25321 agcagatggt gggatcttgt ttttagacga ggtacatcgc ttaacaccag aaggtcagga
    25381 aaaactgttc acctatcttg atcaaggtgt gatttatcgt atgggagaac ctaatttgtc
    25441 acgccggatc aaaacacgtc tcttttttgc tacgactgaa gagattacta gtcatttctt
    25501 aacaactttc attcgaagaa tacctatccg aatcgaacta cctgcactta atcagcgtag
    25561 tcgtaatgaa cggctagaac tgatttactc tttttttctc gaagaacaaa gaaaaatggg
    25621 gagccctttg tcagtcagtg gaccagcttt gtcactttta acaagtcaga aattatccgg
    25681 aaacatagga gagctgaaaa atatcgtcaa agtttcagca gcaaaagcat atgctgaaca
    25741 gcgtgaacag cctgaaatcc atgtcacgat ccatcatttg caaaaagaac tacttgcgca
    25801 gcctattact aaaaatacag cacagcaagg aatctatatt acgcaagacc agaccttaga
    25861 gcaattaatg gagaagcaac agcccgaaca gcagcgaatc gttaaaagtt ttgagcaaat
    25921 cctaattgat ttcaagaaaa ataactgtct gctatattct tgcgaaggaa aattaaagca
    25981 agaagtgatt caattatttg attttttgct gtttgagacc agtagacaag aaaaacacga
    26041 gctgctggtt tattggacac aatctatccg agagaccttt cgacaaatgg aaactgccta
    26101 tcaaatcaaa ttcgatggaa acagtgtcta tgccttgagt tactatctct atcagcgaag
    26161 cactatcaaa tggttaccgg aagaacatga tattatccaa ctaatcaaag aattagaaca
    26221 acaagtttct cagtcttatc catctagtta tcactatgtc caacgaattc tggaattaag
    26281 taagatcaaa ttagatattg aagacacaag tatggatcgg attttactga cgatctatct
    26341 aaaaaaagcg aaatggtcaa aagaaaaacg actgccaaaa gcgatgattg ctgctcacgg
    26401 ttatgcaact gctagcagta tggcaaatgt agtaaatcgt ttattacaag aggatctatt
    26461 tgaatcattt gatatgccac tagatgtcac accacagcag attgcttcag aaatccttga
    26521 ttattgcgaa aacagcgatg tttcaaatgg attgatcata ttagtagaca tgggatctct
    26581 gaaagaaatc catcagtttt ttaaaaaaca gttatccgta ccgcttttga ttttgaataa
    26641 tgtgacgaca cctttagcaa tcacagtagg ggaatgcctg caaaaaaatg tatcattaga
    26701 agagatagca gaagagactg ttcgacagat ccagccagaa tggcgactgc tctatccaga
    26761 ggaaaacaaa cccaaagcac tcattactac ttgcttcact ggaatcggta cggcggtcca
    26821 cttaagtgaa ctgctagaaa aaagcttacc tacggcttgt cagttgaaaa tcatcccata
    26881 tgaatatcag caattaaaag ataagaaaaa cagtgaccca ttattttcca tatacgaagt
    26941 cgtaggaatg attggcacca cagatcctga tatcaccaat atcgactatc tttcattaga
    27001 agacctcatc tcgggggaaa agatgtctgt actagctgaa tggttggaca ctactatgaa
    27061 tgcttcagag aaggaaatat tcaatcagcg catcattcgt aatttttcat tggaaaaagt
    27121 actggattcc gtgactattc tagatacaga gaaggtgatg ggagaaatcg atcattttat
    27181 gagagaatta gaggtgcagt tgaatcgaag catcagcaat cccaaaaaat tagcgttgta
    27241 tgtccatgtg agctgtctca ttgaacgatt gatccgacaa atgccaatcg aaacctatca
    27301 aggattagag aaatggaagc agtgtcaaaa agaagggtta tctgctatta aatctgcgtt
    27361 tagtgtcatt gaagagcatt atagtgtcat gatccccaat tctgagattg cctatatcta
    27421 tgatattttg agtgaagata cagagtttct ctcgatagaa gaagaatttt gaacataagc
    27481 aagttgttgc cactaatttt ggcatgcaac ttgctttttt agtatgtgta agtgaaaaga
    27541 ggagatgaaa aagtggatag agaaattatc ttagcttccc atggaaaatt tgcttcaggg
    27601 atattagatt cattagagct gatctatggg aaaaatcatt ctattactgt attcgattgc
    27661 tatactgatg agaattttga tttagcggaa acagtaaggc agctttttat gaggtacaaa
    27721 gataaagaaa tcattgttct gacggatctt tttggcggaa gtgtcaacaa cgaattctta
    27781 caatatatca atcgggatca tgtctatctc gttgccggat tgaatttgcc actattgatt
    27841 gagctagtat ctcggttgga cgctgaagta gagacaactg ttttgatcca gcaggtgcta
    27901 actgattcaa aaaaaatgat ccagttttgt aacgagcggc tcaatcagaa aatagaagaa
    27961 gacgaatttt aggaggaaga aaaatgattg tattgacaag agtcgaccat cggttattac
    28021 acggacaagt agctttttca tggacacaaa caataggcgc agactgtatt ttgattgcta
    28081 atgatgatgt acctacgaat gagatacgaa agacaacgat caaattagcc aagccacaag
    28141 gagtcaaact agtgatcaaa tcaattgatg actcgattgc cgcgttgaaa agcggggtga
    28201 cagataaata taagttattc atcgtagtgg aatcgatcga ggatgcatat aagctggcag
    28261 aagcgtatcc agaaatcaaa accatcaact taggagggat caaggcaaaa cctggtactc
    28321 gcagcatcgg aaaagcggta aatattttac cagaagagga ggaacgcttg aaacgattaa
    28381 ttgacaaaca aatagaagta gaaatccgtc aagtaccagc agataaaaaa gtggatgtaa
    28441 gagaagtttt gtaagaaagg aagaacctca atgattgtac aagcagtctt attaggaatt
    28501 gttgcatttg tcgcacaatc agaatatgca ctagggacat cgttgctttc tcgtccgatt
    28561 gtgacggggc tgtttacagg aatcgtgtta ggtgatgtaa aaactgggat cattatgggc
    28621 gcaactttag agttagcatt tatcggatcg ttctcagtag gtgcttcgat tccacctgat
    28681 gttgtgaccg gtgggatttt agggacggct tttgctatta cagctggagc cggtacagaa
    28741 accgcgcttt tactaggttt gccgattgct acgttgacat tgatattgaa aaatatttac
    28801 ttagggcttt tgattccaat tatgaaccat aaagcagaca attatgcaga agaaggaaat
    28861 tataaaggag tcgagcatat gcacttgctt gccggtatcg gtctttcctt gatgcttggt
    28921 gttgtggtaa tggtttctta tatggtggga agcaatacga tcggaaatct attaaatatg
    28981 attcctgact tcgttcaaaa ggggttgtca gtagctacag ggttgattcc agctcttggt
    29041 tttgcgatgc ttgctcgttt gctgatcaac aaacaagttg caccatattt tttcttaggt
    29101 tttgctatag cttcttactt agagattcct gtgaccggag tagctatttt tggtgcgatt
    29161 ttagcagttg tggtagtcaa tattatgaat gtccgtcaac taccacttca aacaactgca
    29221 ggggaggtag aagaagatga agaattctga gatcaaaaac agcaaaataa cgaaaaaaga
    29281 gctaaatcac gtattttggc gttcttttca aatggagttt tcttggaatt atgaacgtca
    29341 gatgaatatg gcttatgttt atgcaatgat tccgattttg aaaaagttat atcagtcgaa
    29401 agaagaaatg gcagcagctt tgaaacggca tctagagttt tttaacacga ccccacatat
    29461 cgttacactg attttaggaa tcacggctgc aatggaggaa gaaaataagg atgatcctga
    29521 atttgatgtg actgcgatcg atagtatcaa aacatctttg atgggacctc ttgcagggtt
    29581 aggagattct ttcttttggg gaactttgcg attgattgcc acaggtgtgg gtacctcttt
    29641 agccatgcaa ggaaatattt taggccctat cttgttcatt ttgattttca atattccgca
    29701 cattctgttt cgctatctag caacaggttg gggatatcgc ttaggaacgg gttttttgaa
    29761 aaagatccag gcaaacggta tgatggaaag tttgacatta ggcgcgtcta ttattggact
    29821 gatggtcgtt ggagcaatga ctgccacgat gatcaccatc aatattcctt taaaaatcgg
    29881 ttcaggagaa aatgctgtga ctgttcaaag tatttttgat gatatcgttc caaatatctt
    29941 atgtcttgga gcatttggca tagtgtttta tctattgaag aaagaagtga aaccattaac
    30001 gatcttgatc ggactagctt tctttggaat ttttggttcg tggataggga ttttttaaaa
    30061 aaggagcaga gaaaatgttt acgatgcaag attatatcta tgaagaaaag gaagtactaa
    30121 gtacgatctt gaaaaagaat gatttttcga caagagaaca tatgaaaaaa acagtgaatt
    30181 tactgatctt agcaacgggt tcatcttata acgcttgttt agcagcgaag ccagcattgg
    30241 aatcttatgg tgatcttact gtcgatattc aagaaccttt ttattttttc aattatggaa
    30301 aactttctcc ttcaatcgat actgtgattg ctgtgtcaca aagcgggaaa agtgcttcta
    30361 ctgttgaagc agtaaaaatg atacaaaaac aagggttacc tgttgttgct atcacaaatg
    30421 acgtgcaaag tccacttgct ttagaagctg cacaaattat tgatttaggt gccggggtag
    30481 aatcagtagg cttcgttaca aaaggctatt ctgcgactgt tttacagtta ctactcttag
    30541 ggataggaat tggaataagt aaaaataaaa tcagcaaaaa aatagaacaa gactacatgc
    30601 aacagttgcg caaaataatc aaccatttac cagcgattat tcaaaaaacg gaagaatttt
    30661 ttgatggata tcaaagttta tttcgtttag cacagcgttt cgtcaccatt ggatatggtc
    30721 caaactgggg aacagctaaa gaagcagaga cgaaattgac tgaaacaatc cgcgttccgt
    30781 cacaaggatt tgagttagaa gcttatatgc acggcccata cctggaggca gatgcttcgc
    30841 atttgctatt ctttattgaa ggggaaagtg taaataagga acgttcgcaa aagttgcaaa
    30901 gatatatgag tcggtacgtt ggagagactc tcaccattac cacaaaaaaa gcaagaaacg
    30961 agaaaacact tggattagca atagaatgtg atgaatatct gtctgtatta gcgcttgtcg
    31021 ttccgtttca actattcgct tataaaaccg cagtagctaa aggtattgac ttgaacaaaa
    31081 agatttttga agactttgat acagtcttga aaagtaaatt ataagaggtg gaaatcatgc
    31141 tgaaattcaa tgaagaagaa caaatcaaag caataaaagg cgcactagct ttacgtccgc
    31201 aagtagaaga aatcatcgat aaactttatg cggaaaaatt tgacgctgtc tattatctag
    31261 gaatcggtgg aacgtatgct tcctcgatgc aagctgtcac ttatatgaat gggaaaagca
    31321 acttgcctgt ctttgtacag catgctgcag aatattacac tactggaaac aaaagattaa
    31381 caaaagattc tatcgttatt ttgtcctctg ttaccggtac aactcaagaa gtagtgaaag
    31441 cagtagaaca aatcaagaaa gtaggagcga cactgattgg atttatcgat aaagcgaaca
    31501 gtaagttgtc tcagctatgc gattttgtgg tcacttatcc agctcctgga acagaacaaa
    31561 tcaaattttt tatggcagca gatcgattga tgtatttgaa tggagaattc gaagcttatt
    31621 cagaatacta tgaacagctc gaacgttatt taccaacagg gttagtggaa gcagagaaaa
    31681 aagcagatgc atttggctta tcatttgcag aaaaacatcg acgtgatagt atgcattatt
    31741 ttattggagc agggaatcaa tggggagctg tttattcata tgccatgtgt tactgggaag
    31801 aacaaagctg gcttccatcg aaatctatcc atgctgccga gtttcttcac gggacgttag
    31861 agatcgtaga agaaacaacc ccagtcacat tatttttagg cgaagatgaa cagagagtgt
    31921 tatctgaacg tgtggctaaa cttttgccaa aaatttgcag caattataca ttgatagaca
    31981 caaaagacta tccagtagaa ggtatcagtg aaaaatatcg cggacgtgtt ttgtctttct
    32041 tattgatgca tgtagtgaca caacgcatcg atgctcatgt ggagcagttg aactgccatc
    32101 cattagagat acgccgctac tatcgtcagt ttgattatta ggatagactg gataaaaaga
    32161 atataaaaaa taaagagagc agcgataact gctcccttta tttttttaaa atattggcat
    32221 caattacgtt ataaaacaca ttttttgcat tatctacagt tcaacttata atctgtttaa
    32281 tgggacatgt gggtgccaac cattttttgt tatgcaatag tactatttag ttgttgcatg
    32341 gatccgtagt aaaagtccaa gtacaacgag ttgcgccagt ttacatagcg ttttgtatcc
    32401 agaatgttga ctaaaacaaa agttcctatg tcaaccgtca acagagacaa tctgtccgtt
    32461 gcaggacctg acagatttag aaatgttcaa tctgtctctt atgtatttta aatcaatact
    32521 cactaggaga agtttcctaa cctcctaata gtaatgctgg tagtaacatt gtcaaaactg
    32581 cttcctctta ggaacaagca aagcataacg agtgtaaaaa taaaatgtag actattgtaa
    32641 catatcattg attatttcaa gtaaaaacga taaaagaagt aaacaaacac ttaaaaacaa
    32701 tggaaattag tcccaacttt aagaaatgta tactataatg gaaattatca attatttatt
    32761 tggaggaata tccatgaaac aaaaaatcgc agttcttggt cctggatctt ggggcactgc
    32821 tttagcacaa acattggcag aaaacgggca tgatgtccgt atttggggaa atgtacctga
    32881 acagattgat gaaatcaata agtatcatac aaatcagcat tttttacctg atttgacgat
    32941 cccagaatcg attatcggat ataaagaatt ggcagaagca gtggataacg cagatgctat
    33001 tttatttgtt gttccaacaa aagcgattcg ttcagtcgca caggaactta ttggtaaaat
    33061 gaatactaag ccaatcatta tacatgcaag taaaggacta gaacaagata cgcataaacg
    33121 aatctcagaa gttttggctg aagaaattcc agaagaaaaa agacaggcaa ttgttgtatt
    33181 atctggtcct agccatgctg aggaagtggc agtacatgat atcacaacaa ttacagctgc
    33241 aagtattgat caaaaagcag cagcctatgt acaaaaactg ttcatgaatg attatttcag
    33301 gatttataca aataatgatg tgattggcgt agaaactggt gcagcactga aaaatatcat
    33361 tgcaattggt gccggcgcta tccatggatt aggattcgga gatgatgcaa aagcagcaat
    33421 catgactcga ggattggcag aaatcagccg tcttggtgtc gcgatgggtg ccaatcctct
    33481 gacatttatc ggtttgagtg gtgtggggga cttgatcgtt acttgtacaa gtgttcattc
    33541 tcgcaattgg cgtgccggta acttgttagg acagggacat aagctggaag aagttctaga
    33601 aaacatggga atggtcgttg agggtgtggc aacgacaaaa gcagcagtag agctagctca
    33661 acagctaggt gttgagatgc caattactca aacaatctat aatgttttgt ataatggaga
    33721 agatatcaaa aaagcagcaa aagaaatcat gttacgtgac ggaaaaatgg agaatgaatt
    33781 ttctcttcgt taaatagatg atcaatagtt aatcgtcgtt taggaggaac agcaagtgaa
    33841 ggtcaaaaaa gcagtcattc ctgccgctgg gctaggaaca cgttttttgc cggcaacaaa
    33901 agccatggca aaagaaatgc ttccaatcgt ggataaacca acgatccagt ttattgtgga
    33961 agaagcattg gattcgggaa tcgaagacat cttgatcgta acgggaaaag aaaaaagacc
    34021 cattgaagat cactttgatg caaatatcga attggaaaac aatttgcggg aaaaggaaaa
    34081 aacagaatta ctcgctttag ttgaagaaac gactcaagtc aatcttcact tcatccgtca
    34141 atctcatcca agaggactgg gggatgccgt gcttcaagca aaagcattta taggaaatga
    34201 accgtttgtc gtcatgctgg gggatgattt gatgaaagat gatatcccat tgactcaaca
    34261 attgatgatg gattatgaag aaacacaagc ttccgctgtt gccgtcatgc gtgtaccaga
    34321 aaatgaaaca tctaaatacg gaattattga tcctaaaaca gatagcgaaa agggtcgttg
    34381 cagagtaaaa gggtttgtag aaaaacctga aatgggaaaa gcaccaagta atttagccat
    34441 tatcggacgt tatctactga ctcctaaaat atttgagata ttagaaactc aagaaccagg
    34501 agcaggaaac gagatacagc taacggatgc acttcagact cttaaccaga cagaggcggt
    34561 ctatgcgaga gagtttaaag gaaaaagata cgacgtaggc gataagttag gatatatgaa
    34621 gacaaatatt gaatatggac ttcaacattc ggaaattggg acttcattaa gtgcatatat
    34681 tatccagttg agtaaaaagc taagaacaga aagttaactg gaaataagtg gcctgctgag
    34741 aatgaaaggc tatttgttat taaagcggca gcttgtgcgt catttgcgca actgtcgttt
    34801 tagttttttg actctagatc agttgagtcg tggaaaacga aagatagaaa aagactttcg
    34861 tgaatagatt cagaaaatat tatgctaatg gtttaatttt tttttaagtt gtataaaaga
    34921 aaatgattac ataagagaaa tgaaagccaa gccagaagat tcatagtaga ataaaaaggc
    34981 gaatttttta attataaaaa aaggtgtgtg ttcactatgg gaaaattagt cgctgttgca
    35041 cagtcgctgc ttgatatact caagtggctg atggtaggaa gcaattggat atttgtgttg
    35101 ccactattgc ttattagtct atttatcatg tttcgcatgg tcagaaaaaa agaaacgttt
    35161 ctgattttta tctggtatgc agcatccgtt ggggttgcta ccttgatggt tgaattggcg
    35221 ttaggtagtt gggaagcttg cgtatttgct ttattttttg ctgtactgta tctaatcatt
    35281 tatatcccat atatgaaaag aaagtctcgg ataggcagaa aaggtagaca tacaactact
    35341 ttttctagta cagattctct cgaacaaagt agaagaacga gaagaagacg gtaatattta
    35401 gtaggtatac gcaaaaaaag ataaaataat ggataaacta ttgagatgag agatttattt
    35461 aattggtgga aaaaagcttt tttcacttat ataaaagaat cttttttaaa ggaatgcttg
    35521 ttgtatcggg ataagccatt ccttttttta tgttatttat atatatataa atcataccaa
    35581 tgtttttttg tattttcttg cttgcacttg gataagagat tacttacaat aaattcagat
    35641 agaaacagct gaataaaaaa aggctccctg acccttagtt ggcgctaaga atcagggaat
    35701 gaccagtcac acacatacac cctgaccgat cattttgcca tagtcaatgc agtgcatcga
    35761 cctaatttat tgtacctaat ctagggtgaa aattctaccc ctatgtagat attttccatg
    35821 gtctgcacgt tgttttattt gctatgtcaa ggtattgggc gtattcgttc aatgcctttt
    35881 ttgtgtttga aacagcaaag accacatgtg ttactgtcta actactgttt ttttatgtac
    35941 ttccttagat taggcagctg tttctattca tgtcaagtat agctaggcgg gagagataaa
    36001 tgagtttatg ttattttgac tattatcacc aattggaaga gaaattaagg atagaagagc
    36061 cgctgatgct tcaagctggc acttggatcg cgaaacaaat taatcaaggt ggtagattgc
    36121 agatatatgc tagccgcaca ctaagtggtg tagcatttga attttgggat caaaccccgg
    36181 atcttgtacc aagtatattg attgaaaatc cagccggagg tgtctatgaa acgctagaag
    36241 gtgcaggaca ggcaattatt gatcagcttt ctgtcaaatc agaagacatt tttcttcttc
    36301 tttcgaatga aggaagaaac ccggcaatca tcgaactagc tcagtggatc aaagaaaatg
    36361 gtcatccatt aatcattgtt actggatttg atttgtcacg aagtatcaaa tcgcaacata
    36421 gcagtggttt gcgattattt gaatttgctg atttggtttt ggacaaccac gccaatttac
    36481 atgatgcagt cttgactttg ccaaatctag atccagcgat ctgcggaaca gcctctcttg
    36541 caacgatctt tttgctgcag caagttttgt attttacagc aaaacagcta gtccaggaca
    36601 caagtggaaa atagttatcc acatgttgac aaagttcctt aaaaaaataa tgttccacat
    36661 aaaaatggag cgtttgaaaa aaagaaaacg attattaatg aggattaaca acgactactt
    36721 tttttgtttt agttatttta agatggatca tctttgattt taagcttgtt ttgtttaaag
    36781 tttgttattt ttataagttg tttcacagtt atgagaaatg agttataaga atatgtagtg
    36841 tcagaaaaat aaaaagtagt ggaaaaagag acaagaaaga atccatatgg attctttctt
    36901 gtctcttaat acacgttgat gaaagagtct tccccaaaac tctttacaaa gtaattatag
    36961 tacatttgtt atcattattg caatgaagtt tacctgatat aacaaaattg tccaacagga
    37021 tacctttttc taatagaaat aaaatacaca aaaattgaag gatagataat ggatatttat
    37081 aagtgtttat tatttttttt gcaatgaaat tcaatttttc aatgattgt
//
LOCUS       DAFLWC010000016        35886 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.016, whole genome shotgun sequence.
ACCESSION   DAFLWC010000016 DAFLWC010000000
VERSION     DAFLWC010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35886
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.016"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            101..1066
                     /locus_tag="L1V17_000791"
     CDS             101..1066
                     /locus_tag="L1V17_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBN1235575.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(1123..1353)
                     /locus_tag="L1V17_000792"
     CDS             complement(1123..1353)
                     /locus_tag="L1V17_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HBN1235576.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(1439..2326)
                     /locus_tag="L1V17_000793"
     CDS             complement(1439..2326)
                     /locus_tag="L1V17_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBN1235577.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(2415..3638)
                     /locus_tag="L1V17_000794"
     CDS             complement(2415..3638)
                     /locus_tag="L1V17_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBN1235578.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(3655..4701)
                     /locus_tag="L1V17_000795"
     CDS             complement(3655..4701)
                     /locus_tag="L1V17_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBN1235579.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIRSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(4865..6592)
                     /gene="ptsP"
                     /locus_tag="L1V17_000796"
     CDS             complement(4865..6592)
                     /gene="ptsP"
                     /locus_tag="L1V17_000796"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBN1235580.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(6592..6858)
                     /locus_tag="L1V17_000797"
     CDS             complement(6592..6858)
                     /locus_tag="L1V17_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HBN1235581.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            7337..9571
                     /locus_tag="L1V17_000798"
     CDS             7337..9571
                     /locus_tag="L1V17_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1235582.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            9719..10039
                     /locus_tag="L1V17_000799"
     CDS             9719..10039
                     /locus_tag="L1V17_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBN1235583.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(10244..10468)
                     /locus_tag="L1V17_000800"
     CDS             complement(10244..10468)
                     /locus_tag="L1V17_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HBN1235584.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(10666..12246)
                     /locus_tag="L1V17_000801"
     CDS             complement(10666..12246)
                     /locus_tag="L1V17_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HBN1235585.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(12647..14023)
                     /locus_tag="L1V17_000802"
     CDS             complement(12647..14023)
                     /locus_tag="L1V17_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBN1235586.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(14151..15269)
                     /locus_tag="L1V17_000803"
     CDS             complement(14151..15269)
                     /locus_tag="L1V17_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBN1235587.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            15411..15845
                     /locus_tag="L1V17_000804"
     CDS             15411..15845
                     /locus_tag="L1V17_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1235588.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(15923..16456)
                     /locus_tag="L1V17_000805"
     CDS             complement(15923..16456)
                     /locus_tag="L1V17_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HBN1235589.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(16550..17728)
                     /gene="mutY"
                     /locus_tag="L1V17_000806"
     CDS             complement(16550..17728)
                     /gene="mutY"
                     /locus_tag="L1V17_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HBN1235590.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(17721..18518)
                     /gene="recX"
                     /locus_tag="L1V17_000807"
     CDS             complement(17721..18518)
                     /gene="recX"
                     /locus_tag="L1V17_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBN1235591.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            18625..20007
                     /gene="rlmD"
                     /locus_tag="L1V17_000808"
     CDS             18625..20007
                     /gene="rlmD"
                     /locus_tag="L1V17_000808"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBN1235592.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(20181..20759)
                     /locus_tag="L1V17_000809"
     CDS             complement(20181..20759)
                     /locus_tag="L1V17_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HBN1235593.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            21081..21551
                     /locus_tag="L1V17_000810"
     CDS             21081..21551
                     /locus_tag="L1V17_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBN1235594.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(21659..22885)
                     /locus_tag="L1V17_000811"
     CDS             complement(21659..22885)
                     /locus_tag="L1V17_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBN1235595.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(23639..23839)
                     /locus_tag="L1V17_000812"
     CDS             complement(23639..23839)
                     /locus_tag="L1V17_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBN1235596.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(23973..24581)
                     /locus_tag="L1V17_000813"
     CDS             complement(23973..24581)
                     /locus_tag="L1V17_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBN1235597.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(24666..25136)
                     /locus_tag="L1V17_000814"
     CDS             complement(24666..25136)
                     /locus_tag="L1V17_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBN1235598.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(25184..26098)
                     /locus_tag="L1V17_000815"
     CDS             complement(25184..26098)
                     /locus_tag="L1V17_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBN1235599.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            26244..27047
                     /locus_tag="L1V17_000816"
     CDS             26244..27047
                     /locus_tag="L1V17_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HBN1235600.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            27225..28172
                     /locus_tag="L1V17_000817"
     CDS             27225..28172
                     /locus_tag="L1V17_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBN1235601.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(28240..28533)
                     /locus_tag="L1V17_000818"
     CDS             complement(28240..28533)
                     /locus_tag="L1V17_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HBN1235602.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYNPNLEEPTYHFKKQ"
     gene            complement(28561..29226)
                     /locus_tag="L1V17_000819"
     CDS             complement(28561..29226)
                     /locus_tag="L1V17_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBN1235603.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(29366..29998)
                     /locus_tag="L1V17_000820"
     CDS             complement(29366..29998)
                     /locus_tag="L1V17_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1235604.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(30005..31072)
                     /locus_tag="L1V17_000821"
     CDS             complement(30005..31072)
                     /locus_tag="L1V17_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBN1235605.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(31069..31800)
                     /locus_tag="L1V17_000822"
     CDS             complement(31069..31800)
                     /locus_tag="L1V17_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HBN1235606.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(31969..32448)
                     /gene="greA"
                     /locus_tag="L1V17_000823"
     CDS             complement(31969..32448)
                     /gene="greA"
                     /locus_tag="L1V17_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBN1235607.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(32584..33759)
                     /gene="mltG"
                     /locus_tag="L1V17_000824"
     CDS             complement(32584..33759)
                     /gene="mltG"
                     /locus_tag="L1V17_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBN1235608.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            33963..35132
                     /locus_tag="L1V17_000825"
     CDS             33963..35132
                     /locus_tag="L1V17_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBN1235609.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            complement(35399..>35886)
                     /locus_tag="L1V17_000826"
     CDS             complement(35399..>35886)
                     /locus_tag="L1V17_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235610.1"
                     /translation="LNYSSVVNMVKEMNFQGTYSNEQMENKLEEFENFDYVPIGYKKD
                     QLLLKNHQVTEDGQVIYSSFSPNKDEITFTFKSSKGKTIVLPVFRYKGLTVTVNSKNA
                     TVLKQGGPFVTVKSESGINKVTIRYSYTFFSKISLFISIITLIVLLFYCIKLKIRTSH
                     E"
BASE COUNT        10829 a         7206 c         5916 g        11935 t
ORIGIN      
        1 aaagtatttt ctgtgaacag aactatagaa ttccctaaaa cttgtccatt atttcaaaat
       61 ttgttatagt ctttttattc aaagcgtaaa aggagatcct atgttaaaag aaaaaatgaa
      121 aactctcccc atgctgccgg gtgtctatct tatgaaagac cgagatggta aggtcatcta
      181 tgttggtaaa gcaaaacggc tcaaaaatag agtaagcagc tattttcatc agaataaaca
      241 gcattcaaaa aaagtattac gtatgattca tcatataaca gattttgatt tcgtcgtagt
      301 agacacggaa ttagatgctt tattgctcga gtgtcaattg atccaacatt accgtccttt
      361 ttataaccga caaatgaatt atttcagtaa ttataattat gtacatatta ccaataaggg
      421 atttgtatta acagatactc ctacggctcg aacatacggg ccttttcgtc tctataaaaa
      481 aatgccgtct attttgcgta taatggaaga aacttatcaa atgccttggt tgtctgaaat
      541 tagtttgtta gctttgcgag tccagcttcc tgacctacag gaaatgactt ttgaacagaa
      601 aaaaaaggaa ctccaagggc tgtttcaagg ccgaaataaa aagctactga cttacttgaa
      661 aaaaagacaa caacatttca tctatcagtt gaatttcgaa aaagccggta tgcttcaaaa
      721 agatatcgaa ttagttactt attttattag acggatccag gaacaaaagc agtttttaag
      781 aacaccatcg ctcaccttca gcatgccatt agcagcagat gagagtcaga aaaagcacta
      841 cctcgtttgt tatggtcaac ttgcagaaac aatgattacc tctggtgacg tttctcctga
      901 cttctattat gaaaagaaag aagctcattt atctttgaaa cgtcaattgt caaaagaaga
      961 aatcgatcct gtacaaatct tgatcagtta ccgcaaaaaa ttagaaaaag aacagtttga
     1021 aattgaactg ttaaacaaaa aagaagctga aaagcaacta aattagttgc ttctcggctt
     1081 cttttaggca tcttcaactt caaatgtcaa ttatcctaaa atttattgga ttaagtcata
     1141 gatttccatc gctacgatat cgatattatc aaattcgtat tgctgatgag tatctgtttc
     1201 agttaattca aatgtatcgg tcgctttatc ataagttact gtacacttct ctacgccttc
     1261 tttttcaaaa cggcgaactt gcagttcatt atctgctgac tcgaccatag cctccagtcg
     1321 ttttatgatt gcgactaatt gtgaatgtgt catcggaggt cctccttttc ttatttctgt
     1381 tatattgtat caaaagcata gcctacttgc attgattttc tctaaaaaaa ctcgtttttt
     1441 atgatttttt ttctggtatt tttccttcag gccaccaaag tttgatcaaa gcttgggttc
     1501 cgtcattctc aaaaccttta tctgccaact cttcatatag tttcaatgct tgggtagttg
     1561 ctggcaatac aagatccatt ttttctgctt cttctaatgc aatctttaaa tctttgataa
     1621 aatgtttgac aaaaaaacca ggtgtgtaat cttcttttaa aatacgagga gaataattgc
     1681 ttaaagacca gttagctgca cttccacctg aaagcgtctc aatcactttc tttaaatcaa
     1741 gtccgttttt ttgtgcatag acaagcattt ccgtcattcc tgtcatcgta cctgcaatca
     1801 tgatctgatt agccattttt gtatgctgac ctttcccagc agaaccatgc aatgtaaatg
     1861 tcgtaccaaa ttctttgaat aaaggcagta cttgatcata aacggcttct tctccaccga
     1921 ccatgatcgt cagtgtacca ttctttgctc ctaagtcacc accggatacc ggtgcatcta
     1981 acgcatctgc gcctttttct tttgctgttt ttgcaatttt ttctgccagg cttggtgtac
     2041 ttgtagtcaa atcaactaaa atatgtcctg agatatctgc agaaaaaatc cccgactgtc
     2101 catagtagat ttcttctaca tctttggggt aacctaccat tgtaaagaga atattacttt
     2161 gttctgctac cgcttttggt gtatctgccc agatagctcc ttctgttact aaaggatcag
     2221 cttttgcttt tgtccgatta tagacagcta cttcgtgtcc tgcttctagt agatggcgtg
     2281 cgacagcact tcccatgacg cctgttccga taaaaccaag tttcattttt tcgacctcct
     2341 aaaaatcaaa aatccttgct tctatgctag tatacgctag aaacaaggat tttttcataa
     2401 aaaatgtttg aattttatct tttaaatgaa tttaatttta ttttgattcg ttcaatcgag
     2461 tcttcttctt cttttcttcg catctcttct tcatgataaa caaccatgtc ttgataaaat
     2521 tcgatcatag cttcgccgaa atgtgtagat gaaatatcat aaagtttagc ttctaaaact
     2581 tttggatctt taggaacttc actggaaata taatcaataa gtgctggtgc aaagtcttcg
     2641 tcggtttcaa aagttttccc taatgaagga tgatcgaaca atcggttcaa ataagcattt
     2701 ccttccacga cacaaggtgt tccggctgcc atcgcttctg tataagtaag cccttgtgtt
     2761 tctgaagtag aagcactgac aaaataatct gccgctttat aataaagtgc tacatcattg
     2821 ttgtccactt ctcctgtgaa ctgcacaaat tcttctaact gcagttctga gatcaattcc
     2881 tctaactctt ctacataagg tccttttcct acgataacta atctggcgtt aggataagcg
     2941 gagatgacct gaggaaaccc attaatcaag gcttggatat ttttctcata agaaatcctg
     3001 cttaaagaaa gaatcatcaa atggttttcc tgaagaccta gtgactccct taatttgctg
     3061 atatcctgct gagtgatatc agaacgtttg aatttttcaa tgtcgatacc agtaggaatc
     3121 acgcgaagcg gtgctattac accatagctg cgtaatgtat caataacacg ttcacttgga
     3181 caaactacac ctgtcgtatg atttgcaaat aatctagaca agtattttac atgggattgc
     3241 ctgatcactt ttcctttacc gatataatga aggtagtctt catacatcgt atggtaagta
     3301 tggatcagag gtattttcaa cttcttagct accatcttcc caagtatccc tgctccgaat
     3361 tctgtatggg tatgaataag atctagttct agttctttgg caaccaaata agcataccac
     3421 atgcctctaa caacaactct tcgatccttg aaagaaataa atggtacact tggcattcga
     3481 atcacatctt tttccaactt atccgcatta ggatcggtcg ttgtaaaaat atagacttca
     3541 tgcccatgtc tttctaattc ttgttttaat gttttgatcg atgtagcaac tccgctgact
     3601 tgcggaaagt aggtatcggt aaaaaagccg attttcatgt ttttcgcctc caaactagtc
     3661 cttgacctga tttacttttt ttaatttgct agagactttt tcattcagta cactttcgta
     3721 tacattttta agttcttcac cgattttatt gatacttcgc tcttttgctg tttgataacc
     3781 ggcttgtgtc gtactcggta gttcttgatt ggtaatctgt tggatcagtc ggataaattc
     3841 ttcgtttgtc ttccccatat agcagttctt gctatcttct aaccagccat tatacactgg
     3901 aatatctcga acaagtacgt tttgtttgct tgctaaagct tctaaaacaa cgatcccttc
     3961 tgtctcttca taagaaggga aaaagaatag atctgcacct gaatacgcac cttctatgat
     4021 ctctccacga atgtaaccag gaaacaggac attttcagga tgatcttctt ttacaatttt
     4081 ccggatgttc cgaggaatcg agtacatggg aacatgacca aaccaaataa atgtgtattc
     4141 gggcatcttc ttagcaattt ctacgaaatc aatgattcct ttacgttcga aaaacaaacc
     4201 gacacaaatg attacttttt gatccggaga cagtttgaaa tattctctga acttttgttc
     4261 tttcattgga tcagggtgat atttctctaa gtcgatccca ttggaaatag cttgaatcgg
     4321 cacacggata ccatagcttt ccaacaactg ttttgaataa ggtgttggcg tgatcagata
     4381 gtccgctttt tggtacaatc ctaccagata tttttttacg ataggagaaa gctggttcga
     4441 tctgataaag gaatttcgga aatcttcctc tgtagaatgc gcatgataga caactttttt
     4501 tccttctctt ctggctttat tgaccatatt atgactattg attccgtatg tattgatgtg
     4561 caggatgtca taatcttctt tttcatctag tgtataagag ataccgactt ccgtcagagc
     4621 acgtttttga tgatcaagcg cacgcccgat tccagatttt gcaagcatct tttcactttc
     4681 aaaatataat aataccttca ccttacgtcc cccttcactt atatagtata acatagccta
     4741 caaactgtca ctcaaactta agccctattt ttgtctattc ttactgacaa aaacgttttc
     4801 ttaaaaaaga acaaaaaaac tggcgtagct cttttacaag ccacaccagc ttttgatacg
     4861 ttgtttattt tacatattca tgaacaagtt caacgacttc ttccatcata tcgcattctt
     4921 tcaatgcacg atcagcaagt tcagccattt tcgctgtgtc caagcgtttc attaaactac
     4981 gcgttttaag aatagatgtc gcactcattg agaactcatc tagacccata cctactagca
     5041 atggaacagc tgtttgatct ccagccattt ctccacacat acctgcccat tttccttcag
     5101 cgtgtgctgc atcaattaca tttttgatca aacgtaaaat tgatgggtta tatggttggt
     5161 acaagtaaga aacgcgttcg ttcatacggt ctgctgccat tgtgtattga atcaaatcgt
     5221 tcgtacctac agagaagaaa tctacttctt ttgcaaactt gtctgctaag actgctgctg
     5281 ctggaatctc gatcatgatg ccgacttgga tcgtatcaga tacttccttg ccttcactta
     5341 tcaatttttg tttttcttct tcaaagatcg cttttgctgc gcggaattct ttgagtgtag
     5401 ctaccatagg gaacatgata cgtaaattac catgaacaga tgcacgaagc aatgcacgca
     5461 tttgtgtacg gaacatttcg tcgccttgtt cagataaact gatacgcaat gcacgatatc
     5521 ctaagaatgg attcatttca tgaggtaatt gcagatatgg tagttcttta tctccaccga
     5581 tgtccattgt acgaacaact acaggttttc cttccatacc ttctaataca gctttgtaag
     5641 cttcatattg gtcatcttct gttgggaagt ctggagaatc catatacagg aattcagtac
     5701 ggtacagacc aactgcttct ccaccattat tatggacacc aactagatct tttggtgttc
     5761 cgatgtttgc agctaattca aaatgcttgc cgtcagctgt gacagtttct gcatttttta
     5821 atttttccca ttctgctttt tgtgctgcgt aatctgcacc tgctttttca aattcagctt
     5881 tttgttcatc tgtaggatcg atgattacat cgccttcgat cccgttgaca gccaaaatat
     5941 cgccttcttt gactttagca gtaatttctt ttgtcccaac gattgctgga atttctaaag
     6001 aacgtgccat gatagcagaa tgtgaagtac gtccaccaat gtctgttaca aacgctttta
     6061 caaaattgcg atctaattgt gctgtatcac ttggagtcaa gtcatgtgca acaacgacca
     6121 cttcttcgtt gatcattgat ggatttggta aagtaacgcc taataagtgc gctaaaatac
     6181 gtttagcaac gtcacgaata tctgcagcac gctcttgcat ataagcatta tcttccattg
     6241 cttcgaacat accgatatac atatccgtta cttcttttag cgctgattca gcatttacgc
     6301 tgttgtcttt aatattttgc ttgatttgac ctaccatttc tggatctgaa agaaccatca
     6361 aatgggcatc aaatacttgc gcttctgctt cacctaagct ttgcgctgct ttttcacgaa
     6421 tttgctgcaa ttcttcagta gatttagcta atgcagcatc caaacgagct tcttcagccg
     6481 cagtatcttc tactgttgcc ttactgaatg ttaaatccgg ttgaactagc aggtaagctt
     6541 ttgcaacggc tacaccgtca ctagcggcaa tcccttttag catttcaacc attattcaga
     6601 taagccttct ttcttcattg tttcaacgat tgctgccatt gcatcagctt cgtcagcacc
     6661 ttctgcagta atagtaacat cagaaccttg acctacacct aaagacataa cgcccatgat
     6721 tgatttcaag tttactgatt tacctttata ctctaagttt acatcagagt taaatttgct
     6781 tgctgtttgt actaatagtg tagctggacg agcgtggatc ccagtttctg ctactacgtg
     6841 aaattctttc ttttccatat taatcggtct cctttaagtg agtgttgttt ttatgtgagg
     6901 gttttctttt ttagtaattc agagaatcct aacaaatgcc accctttcat ctgtaaagat
     6961 taacattttt tttcgttaga tacaacagtt ttcattcaat ttcagataaa agtattcaaa
     7021 ttattccgga ttctttttca tccttttctt cacattttat aacaaacgtg tttatttcct
     7081 ttttcttgtc gctttctctt ctcctgacgt ttatcattct ttcctttgac cctctttgtt
     7141 ttcatatgaa acgaattact tgcttccctt tttattttta gtataataag agtcaaaggt
     7201 caggaatggt caatagagat ttcacctttt ctacctcata aatctcttaa aaaactaggg
     7261 gttattcttt tacctcatga aaaacgagat gtaaaatatg gatgtaccca tttttgtgaa
     7321 aggacgtgaa tgattcatgc tttgtcaaaa ctgcggcaag aatgaggcaa cgattcactt
     7381 gtatgccact gtcaatggtc agcggacaca actcgattac tgtcagagct gttatcaaaa
     7441 aatcaaaaat caacaaaatg gaggtctgac taatatggcc caaaatgatc catttggatt
     7501 tggcagtttg gacgatcttt tccgttccat gtctcgccaa atgcaacagc aaggaaatta
     7561 tgagcaaaca ccaccaacac aatttggcgg aaacaacaac ttcaatggtg gtcagccacc
     7621 tcaaggcaat acagaaggtt tattgggaga atacggaatc aatatcacag aacaagcacg
     7681 acaaggtgat atcgatcctg tgatcggacg cgatgacgaa atcaaacgag tcattgaaat
     7741 tttaaatcgc cgaaccaaga acaatcctgt cttgattgga gaaccaggtg ttggtaaaac
     7801 agcagttgtt gaaggtttag cacaaaaaat cgtagatggt gatgtaccgc aaaaattaat
     7861 ggacaaagaa gtcattcgtt tagatgtcgt atctttagtc caaggtactg gtatacgagg
     7921 acaatttgaa gaacgtatgc aaaaattgat tgaagagatc cgtcaagcag aaaatgtgat
     7981 cctattcata gatgaagttc acgaaatcgt cggtgctggt tctgctggtg atggaaatat
     8041 ggatgctggt aatattttaa aaccagcttt agctcgagga gaattgcaaa tggttggtgc
     8101 tactacctta aatgagtacc gcatcatcga aaaagacgct gctttagaac gtcgtatgca
     8161 acctgtacgg gtagatgaac caactgtcga agaaacgatc agtattttga aaggtttgca
     8221 aaaacgttat gaagactatc atcatgtaaa atatactgat gaggccatcg aagcagccgc
     8281 aactttatcc aatcgttacg tccaagatcg cttcttgccg gataaagcca tcgatttgct
     8341 agatgaaaca ggttctaaga aaaacttgac gatccaaatc gttgatccta aaacaatcga
     8401 gaaaaaactg caagaagcag aagaacaaaa agttttagct tctcgagaag aagatttcga
     8461 aaaagcagct tattatcgcg atcagatcaa taaacttcaa aaaatgaaag aacgtcagct
     8521 cactgaagag gaaacacctg tgattaccga aaaagatatg gaaaaaatcg ttgaacaacg
     8581 gacaggtatt ccagtgggtg aattaaaaga aaaagaacag acacaactga aaaacttagc
     8641 agatgacttg aaagctcatg tcatcggaca agataacgct gtagatcgag tagcgaaagc
     8701 gattcgccga aaccgtgttg gattaaacaa acagaatcgt ccaatcggct ccttcttatt
     8761 tgttggacca actggtgtag gtaaaacaga gcttgcgaaa caacttgcct acgaactatt
     8821 cggttcacaa gattcaatga ttcgtttcga tatgtctgaa tatatggaaa aacatagtgt
     8881 ctctaaattg attggttctc ctccaggtta tgtcggatac gaagaagctg gtcaattaac
     8941 agaaaaagta cggagaaatc cttacagtct tgtcttgtta gatgaagtag aaaaagctca
     9001 tccagatgtt ttgcatatgt tcttgcaaat cttagatgat ggtcgattga cagatgcaca
     9061 aggaagaacg gtcagcttta aagatacgat catcattatg acaagtaatg ccggaactgg
     9121 taaagtagaa gcaaacgttg gttttggtgc ggcacgcgaa ggtgttactc gttctgtatt
     9181 gaaccaatta aacaactact ttacaccaga atttctgaac cgttttgacg ggatcatcga
     9241 attcagtgca ttatcaaaag aaaacttgat gacaatcgtc acactaatgc tagacgatgt
     9301 caaccaaatg ctggcagcac agcaacttca catcgaagtt cctacgaatg tcaaagaaaa
     9361 attagttgac ttaggctatg atccatctat gggtgctcgt cctcttcgac gcacgatcca
     9421 agaacaaatc gaagatggta tcgctgaatt ttatcttgat cacccttcta tccatgagtt
     9481 gaaagcaaaa ctggataaag atggaaaaat catcgttact tctaaaccag aacgtttggc
     9541 taaagaatca gccgaagaaa cggctgaata aatccagttt tatagcgtga gacggtattt
     9601 ctttgagaaa tgccgtctca ttcttttttc agaaaagtca aaatactgtt cattttataa
     9661 aaaagaaatt ataataagag aaacaagcaa ttaaaaatac ataaaagagg tgagcgccat
     9721 gaaattggta aatgtaacaa acagccattc ccgtcttgta ttaaaccagc ttgaaaacac
     9781 tgatgcccat ctagtcaagg tctacacagc cggaaatacc actattgtct acactgaagc
     9841 ccctgaacat aatgaaattc tgctgatcaa tgacaaacgt aaaatccagc cgaaagaaat
     9901 cgaagatgct aaaaattatt tcttagataa aatcaaagac gccgtttacc acgaggatga
     9961 aatcaaagta atcgaattgg caggccttgt tgaaatctcg attccaaaac atgaattagg
    10021 cgctacatta gccgtgtaaa caaattttga acataataat taaagagcgt gggacaaaag
    10081 taaagaacac ttttgtctca cgctctaaac acgtataaac ggcgaaagca gaagcaactc
    10141 cttcggaaat aagctgaaat tcacgaaaat tgcttttcaa atttttgtga attccagctt
    10201 atttcttgga gttaaacgct tctgtctcag cctctttttc tttctagctt tttgattttt
    10261 ctcttttctt ttgtactttt ctcttttcat tttcagttct acgcgtgtct ttatttttaa
    10321 ctttttcctc tttatggatg attgatcgta ctttttgtgc aatttgctcg tttttgtccc
    10381 agtcttttac atctaataat cgacataatc gtaacatctc ttcttttttc tgtttttttc
    10441 tttcacgtct ttgccattct gtttccatgt gtcacactct cctttcttta atcatatgta
    10501 cgcaaaataa tttttatatt tttttgatta gacatttcta tgattttaat atagtaaaaa
    10561 gagccgtcac ggaaaatccg tcacggctct aaacaaaata tgagaggctg tttttgtttg
    10621 gctattctta ttacttgatg cagggcagct tgtgtcaaga cttctttaca tcaaactttt
    10681 taattttaca ttgggatatt tatccgcaaa ccagcgttct gcaaattggt tctcgaataa
    10741 gaacaacggt tggtcgaaac ggtcacgagc caagatattg cgacttgaac tcatcttctc
    10801 atccaaatct tctggatcga tccagcgagc gattttgtgt cccattggag acatgattac
    10861 ttcggcgtta tactcattta acatacgata ttggaatact tcgaattgta gctgaccaac
    10921 agctccaatg atatattctt ccgttagata tgttttataa agctgaatcg ctccttcttg
    10981 aactaattga tagattcctt tgtggaagga tttttgtttc atgacatttt ttgcagtcac
    11041 tttcataaac agctctggag taaatgaagg gagttcttca taagcaactt ttagttttcc
    11101 ttcgaacaat gtatccccaa tctgataatt gcctgtatca tatacaccga tgatatcgcc
    11161 tgctactgct ttttcgacgt tttctctcga atctgccata aattgtgtga cattgcttaa
    11221 tttcagtttt ttatttgtac gttccaacca gacatccatt cctcgttcga atgttccaga
    11281 acagattcgg acaaaagcga ttcggtcacg atgggctgga ttcatatttg cttggatctt
    11341 gaatacgaaa cctgaaaatt cttcctcata aggacttacc atctgatcat cttgtgtttt
    11401 gtgtccataa ggagctggtg ccaattcaac gaaagtctct aaaaaagtct gtacaccgaa
    11461 gttagtcaat gcagaaccaa aaaatactgg tgtctgatcg ccacgagcaa ttttttcttg
    11521 attaaatgca tctccagcct ctttgattag ttctacttct tctaagactt gttcatataa
    11581 ggaattttca gttagaggat gattttcggg aagcagtcca tcttcatcca attctactaa
    11641 tcgttcatcc tgataatttt ccggacgata aaactctaca cgattatggt agatatcata
    11701 aagaccttct agccctttac ccataccgat tggccaattc atcggataag attcgatatc
    11761 taatagctct tctaattctt ctaacaattc caatggttca cgaccatcac gatctagttt
    11821 gttgataaaa gtaaatatcg ggatgccacg tttttttaca acttggaata atttctttgt
    11881 ctgtgcttcg atcccttttg cactatcgat taccatgacc gcactatcca cggccatcaa
    11941 agtacgataa gtatcttcag aaaaatcttc atgtcctggt gtatccaaga tatttactcg
    12001 tttcccttga taatcaaact gcataacaga actagtaaca gaaatcccac gttgtttctc
    12061 gatttccatc cagtctgatt tggcaaaatt acctgttttt ttgcctttta cggtcccggc
    12121 ttgacggata gccccaccaa acaatagtaa ttgttctgta atcgttgttt tcccagcatc
    12181 cggatgggaa atgatcgcaa aagttctgcg attgtccact tgttgcttta attttggatt
    12241 attcataacc taactccatt tcttccattc aattatttat attttctcta ggcacagatt
    12301 gtccgatctc ttaaagaaag acaatttcat atagggctgt gacaaaagcc gtgtagcagt
    12361 ctctttttcc gagtaaacgg cgttctagag acagcctatc agcaataagc ccacccaagc
    12421 caaaaatacg aaaagctgtt tttgcttggc tgctcttatt acttaatgca ggatagcttt
    12481 ttcacaacct ttgtcaacta ctacaactga atcagtatag catggattca gcgaatgaaa
    12541 aagccaccaa accataagag tcaaatattt ttttgtcagc tgactaaaag aaaagacgtg
    12601 ttgcttgttt attcaagcaa cacgtctttc ataaccaagt ttccaattat cttcttggct
    12661 cgtcatcttc gaattctttt ctgaagtatc ttcgttcttc ttcaggttcc gcttctgttt
    12721 cttccggatc atgaaaaatg acacggattt taaggattcg agaaccttcc atttcttcag
    12781 aaaccagcgt aatattatcg acatcaaacg ataacttttc gccttcatcc ggaatcatgc
    12841 ctaatgctgt aatcaaataa ccagccatcg tatctacatc actcatatgc agatcactgt
    12901 caaaagcttc attgaactca tcaatcagca tacgtccttg gatgatatat tcgtgttcat
    12961 cgattttttc ataaagattc tcaacttcat ctgattcatc atcgatttct ccgacgattt
    13021 cttctaaaag gtcttctagt gttgctaacc caacgacgcc gccatattca tctaataaaa
    13081 tagccatctg attctgcgtc tttttcattt catataacag atcatcaata aagaccgttt
    13141 caggaacgaa taaaggctcc tgcatgattt tcttgatatc taaattatca aagccgaatt
    13201 tatgggcagc ttttagtaaa ttctttgtat gaaggattcc gactacttta tctttgtctt
    13261 cgttataaac agggattctt gaatagtttt cggataaaac ttcattcaca ttttcttcca
    13321 cagtgtcgtt gatatcaatc ataaatgcat ccgttcgtgg gaccatgact tctcgggcaa
    13381 ctttcgtatc aagagaaaaa accccttgga gcatttctaa ttcttcatta ttcaatacgc
    13441 cttcgttttc aagcatataa cgcatttcat ctctggtcat ttttgaatct tcatcatcaa
    13501 aagtcatcgg cgtgatacgc gccaataaac ttgtggaagc agaaagcagc cagacgaagg
    13561 gcttagctac tacaccaatc aagcgtatca gccctgaagt gaactttgcg acttcttctg
    13621 atttatttaa agcaatacgt ttagggtaca attctccaaa aacaatcgat acataggtca
    13681 aaatagccag cacaatgata tttgcaatat tttttgccgc tgtgccgcca cctaataccg
    13741 gagctaaccg ttccgataaa gtattagcta gtgaagcacc agacaaaatg ttgaccaaag
    13801 tgattcctac ttggattgtc gataggaaat tatttggatt ctgcaatatt tttaaaagct
    13861 tttgagattt cacatctcct tcatcagctt tttgctcgat tcgattctta ttgatcgaaa
    13921 caacagcaat ttcggaagct gctaaaaaag cattgatcaa tgtcaaaacg atcaataata
    13981 aaatctgcgc taacagcgac tgactctcag ggtcagcatt cataatcgca ttctctcctt
    14041 ataaaattaa tttttagttt acgatagaaa aaaacgtggc actatagcca cgttaaaatg
    14101 gtatcacaaa gcaattttct ttgcaataaa aacaagtgta ctaaaactac ctacgaggtc
    14161 gtagcaattt tcttcttgtt ttcattttgc ttgtcttctt tgacgatttt gattatatag
    14221 gaaatgatcg tcttgcagat tgcgtaaaaa ggaacaccta agaagatacc aagcaatccg
    14281 gcaatatttc cagctactag aagaacgata atgatcgtta atggatggat tttcagtgat
    14341 ttcccaatta cattaggata aatgatattc ccatccaact gttggacgat tagcacaacc
    14401 acacaacaaa gtaatgcttt taccggatca ttgaagactg ttactagaaa tgcaggtgct
    14461 agtcctagat aaggtcctaa atatggaatt aggtttgtca atcccgcaat gaccccaaat
    14521 aagaaagcat aatccacacc aattaccata tatcctaaaa atgtgaaggt accaacgaat
    14581 aaacattcga ttgcttgtcc gctaatgtaa ttagccaatg ttttattcag ttgccccaat
    14641 aactccacaa tttggtttct tcttttttct gggaaaaact gttggatgtt tggcactagt
    14701 ttttctccgt ctttcaacat atagaacaag atgaatggtg ctgtaatgat tactacggtt
    14761 gccgaagcga tcgttccaac gatcgaacct aaactattgg atactccact aaggaattgc
    14821 tgaatgattg tcccgtaaga aatgtctaat tgctcaaaat atttattgat atctacttcc
    14881 ttgaacaaag gcaattcggc tacctctttt aaccagcttt ctacctgttt gatgaaatca
    14941 ggcatattag atgccaatga ggaaatttgc tgtactagac ttgggatgac actaagtaaa
    15001 atccaaataa ttgctgcaac taaaaggagc agcacaattg cgacagccca tattcttttg
    15061 atttttgctt tcatcaacag cttgacaata ggattcaata aatagtaaag aaagcctgca
    15121 atcagtacag gtgcaaataa cgtggaaaaa aatgtcccga tcggttcgaa aataaagttt
    15181 atttctgatg aaatcatgat caatgcagct atgatcaata attcaagcga ccaaaacatt
    15241 agtttagact gtctaagttt ttcaaacaat agatttcctc ctttctttct tactagtata
    15301 tattatattc gttaaaaatt cttttattct ttttttattt ttgaaaactt gccatacttt
    15361 ttatttgttt tattttccag tatactatac gaaaggaagg tggctagacc atgaaagttg
    15421 tacaaacaaa agatacaatg agcaatattt acttagatgc tgtacggatc aggcatcaag
    15481 tttttgtagt cgaacagggt gtgcctttgt ctcgagaaat agacaaagat gaagcccatt
    15541 gtatccactt cgtcctgtac tcagataaaa aagaaccgca aggaactgta cgtcttttgc
    15601 ctttagaaaa cggaaaaatg aaattacagc ggatggcgat tctttctgaa tacagacacc
    15661 aagggttagg aaaaatattg attgaagaag cagaaaactt tgctaagaat caaggctata
    15721 atacgatttt attaggggca cagtccacag ctgaaacttt ttacgaaaaa ctaggatata
    15781 cagcttacgg cgatcctttt gaagatgctg gcatgcctca tatttatatg aaaaagactt
    15841 tataaaaatt tatttcgaaa aaagcaaaaa acagcaagct tttgagaaaa atctctcact
    15901 ggcttactgt tcttttttgt gtttacttac gcgacaattg cttgtaacgg ttataccaaa
    15961 tatcaatata gccttccgag aacgggccat ctccattatt gatccagtca accagaatct
    16021 tcacattttc ttttaggatg aagtcaatat cgttcgggta attcatcatt ttgctgtgca
    16081 tctcatattc atcgacatcc aatagtcgtt tctcgccgtc aggaaatacc ttgatatcca
    16141 agtcatagtc gatatatttc aaggcctcat cgtccagcaa aaaaggtgaa gctagattac
    16201 aataatagga aacccccttt tctctgatca ttgctattac attgaaccag tattttttat
    16261 gaaaataaac aatcgctggt tcgcgcgtta cccatcggcg tccatcagat tcagtgacta
    16321 atgtgtgatc attcacgccg atcatagagt gttcgcttgt ttttaatacc atggtatctc
    16381 gccacgttcg atgcaatttg ccgtcgtgct tgtaactttg gatcgtcaca aactctcctt
    16441 cttttggaac tcccatagca acccttcctt aagcagcatt ttgtgctttg tgtttgggtg
    16501 ttcattacac cgacatcata attattatat caataaaaat gagctttgcc tagaaaggat
    16561 tcctattgtt tcgatttttc tctaactgat ctaccagttt catttggacc ttaggaaaaa
    16621 cgaccgaatc aaatgcatca ggcttcaacc acttcgaagt tttgttctcg gtaaattctt
    16681 gttctgctcc ctcggttgcc cgtccgtaaa aaaggagaac atgccatttc agatgactaa
    16741 aaatatgagt aacttctcct aaatgtcgtg tctgccaaac aaagagttcc tgcttttcaa
    16801 atgggagatt ttgctcttct tctgctacta ggtcatcaaa cagatcgatt tctggctttg
    16861 tttcccattc ttttttcaat cgctcatact cctcttgtgt cacttccatc attggaaatg
    16921 tccacatatt cgccagcaat ttttggctat ctctttcttc aaaataatac gctccagaat
    16981 gattttgaag agctgcactg atataataaa cgtcttttgg ctttgctttt tttgttttta
    17041 caggaaaact cgtttggatt cctcgtttgt tagctaaaca aaaggcttgg atcggacaag
    17101 tctcacactt tggagaagtt ggtgtacaga tagctgaacc tagatccatc attgcttggt
    17161 tgaattcacc tggatgcttt tcatcaatga ttttccgcat cgcttcatca aagattttcc
    17221 tgctagaagc ttttgcgatg tctgcttcaa tgcaaaacaa tctgctgact actcgcatca
    17281 cgttgccgtc aactgcaggt tctggaagtc caaatgcgat acttgcaatc gcgcctgtcg
    17341 tatatggtcc tattcccttc aatgagctaa tttcttcagg cgtttgcggc atttccccat
    17401 caaattctga catgatctgt ttagcagcag cttggatgtt ccgggctctt gagtaataac
    17461 caaggccctc ccatgctttt aaaagctttt cttctggagc atttgctagc tcttcaattg
    17521 taggaaacca ttccatgaaa cgataaaaat aatcgatcac tgtgtctact ctggtttgct
    17581 gaagcatgat ctcagagatc cagatacgat aaggatcacg attatagcgc caaggcaggt
    17641 ttcttttttc ttgttcatac cattgaatga actgatcttg aaattctttt gtttctttat
    17701 ctgtccattt ttcccattct ttattcactt tcctcttcct tttccgtaat gaatcgctgg
    17761 atcatatcca aatcaaatcc tttttgatat aagctttgct ttacttttag atttcttttt
    17821 ttaggttcaa accttaaatt tcttcgccat agtttatctc cttgtttgac taaataatca
    17881 tattctattt cttgatctgc ttcttgcgga agatcagcta tcgcttgttg gatcacttct
    17941 tgagaaaagc ctttcgtcat caatgtttgt tggatttttc tcaataattc tttttggctt
    18001 tttccgtgat tttttccaaa cgctttttcg gctgtctgat gtgcattttg aacttggtct
    18061 tcaaatgtat attggctgag cgcttgttca atgatttcag gtttcaaacc tttttgctgc
    18121 atctgctgcg ctaatttctt tggtcctttg tcacttaagc gcatattcgt gcgcacataa
    18181 ctttccccat agaccaaatc atcgacaagg tccaattctt ttaagcgggc tacgatttta
    18241 tttcgatctt cttgaaggat ttccttttct tttaagtatg ttcggatttc tttttccgat
    18301 cgcaactgat aacttaagta attcattgct aggtgaaaac cgaaatcagc tccgctactc
    18361 ttcttgatct cttggatagt ttcttcgtct aattcccgtc cttttaataa tcgatagcgt
    18421 actaatacat cttcagatac ttgtaaagct tctccttcag ataaatctac gcgatagaaa
    18481 gggcctttgc ctttactgat tctcgtaacg gttaacataa acatcctcct cgaacatata
    18541 ttctctatca taccacagaa aatccccgta atcaggtatt atatgttaga ataaaccaca
    18601 gaaaaaagaa aaagggagat acttatggca gaaacaattg tcaaaactgg acaaacggtt
    18661 cctttgaaaa tcaagcgttt aggcataaat ggtgaaggaa tcggttattt caaacggttg
    18721 atcatatttg ttccatatgc actaccaaaa gaagaagtac tagtgaaaat cacgaaagca
    18781 actcctcgct atgcagaagg agaattaata aaagtcaaaa aaacaagcaa agatcgcgta
    18841 gtggcaccat gtcctgttta ctatgaatgc ggtggctgtc aattacaaca cttagcttat
    18901 caagctcaat tggattttaa aaaggatctg cttttgcaag cattggaaaa attcaaacca
    18961 gcaggctttc gatcttatca acttttgccg acgatcggga tggatgagcc ttggcattat
    19021 agaaacaaag cacaatttca gttacgaaaa aataagcaga ctcaaaaaat tgaagctggt
    19081 ttatacgaag caaactctca tcagttagtc cctataacag actgcttggt tcaagaacct
    19141 cgaacacaaa aagtaatgaa tactgttgtt caactattga ataaatttga tgcacccatc
    19201 tatgatgaac ggacaaacag tggaatcttc cgcacaatca tggttagaat cggtgttaaa
    19261 actggggagt tacaagttgt ttttattact cgcagtaaaa aattcccgca aaaaaacgca
    19321 atgatccgtg agatcaatga acgactgccc gaagttgttt caatcatgca aaatgtccag
    19381 gcacaaaaaa cgtctctcgt gatgggggat gaaacgatcc acttatgggg aaaagaagcc
    19441 attgaagaac aaatcaatga agtgactttc gatctttctc ctcgtgcctt ctttcaactc
    19501 aatcctcagc agaccgaatt gctttatggc gaaggaatca aagcattaga tgtccagcct
    19561 aatgaaacga tcgtggatgc ttattgcgga gttgggacga tcggcttaag tgtagcaaaa
    19621 caagccaaag aagtacgggg aatggatacc gttcctcaag caatcgctga tgcaaaaaaa
    19681 aatgcggaaa gattaggata tcacaacact cgatatgaag tcgggacagc agagcaagtt
    19741 ctgcctaaat ggttgaatga aggttttcag cctgatggta tcatcgtaga tccaccacgt
    19801 acgggtttgg ataacgcatt gatccaatca ttattgaaat accctccaaa aaaacttgtt
    19861 tatatctcct gtaatgtttc tacacttgcc agagatctgg ttaatttaag taaaaagttc
    19921 aagattgaat atttacagtc cgtcgacatg tttcctcaga ctgcacgttg tgaagttgtc
    19981 gtgaagatga cgagactcgc tgactaaatg aaagaggttg tgaaaaagtc tgccctgtat
    20041 caagtaataa gaacagccaa acaaaaatag ctcttcatgt tttatgaata ctgtacttgt
    20101 gaccgaagag ttaacaggag gacactattt atttaaaaaa agggttgtga catagttttt
    20161 gtcacagccc tttttgatta ttattggata ttcacgtcta tcacttgata aaatgcattt
    20221 gtcgtatcgc tgatattcca tactgctaaa atcacattat atccttttcg atcctgcgga
    20281 agtgtgatcg tttggttgac tgtttttggt ggaacagttg ctttgtcgtc tatttttgtg
    20341 atcaattcaa aatcactaaa tttcaaaggt tgattaggat tccaagttgg tttggtaatg
    20401 tagtaatccc aagtacttgt ccgatgttgt gctgttaaat tccaagtaat atttaatgtt
    20461 cctggattaa ccatgttttt atgccatctg ttagatgtct gttcatctaa aggctcaaag
    20521 ccgctgactc ctgcactagc aatttttcca tcaatgaatg tatttttggt agcttcgata
    20581 ctttgcggtt cccattgtgc tcttccgaca ttttgattta agtttcctgc tgctgatgtt
    20641 cctaggtatg cacggcttcc tggagaagta atataaccat gcgcaaaacc tggaatgcta
    20701 aaaccgaaca accctaaact aactaaccca ataaacaata acgtactaat ctttttcatg
    20761 tagaaacctc cttcatttga taaccacatt gtaaacgctt tattgtatta acacaaacat
    20821 tatgctttta taattttatg ttgaagtaaa aaaggtgaaa aaagtaagat gcagattata
    20881 acagaagtag acgagaaaag tacaaataga aaacatgaga atcaaatcat atgatctttt
    20941 tcaaaaacat cattcatata aacaaatgtt caacttttta ataacaacaa ttatcaattt
    21001 ttttcttact tcacaaacta aatacaggtc ttgctgtgag ccttcatggt aaactaatat
    21061 tatagaaagg agttagtaaa atgaagatga taaaagatat tcgtttttgg gtttgtgtta
    21121 taggaattgt catattaggc tttttatcag ggttgcttag cggaaatccc ggaaaatatt
    21181 actattcttt gcaacttcca ccatttgcac cacctagctg gatatttggg ccgatgtgga
    21241 ccttactgta tatattgatg ggtatttctc tttatttgtt acttaatcac aacaacaaaa
    21301 aacagcgaaa caatcttgtc ggtctttttg tgattcagtt catttttaat tttatatggt
    21361 ctgctctatt ttttaattta agaaatattt tcattgcagc aatcgatatt acacttttag
    21421 ttattttctt gtcagtgctt atgtatcagt tgtggctgca tcatcgcctg gcaatgtggc
    21481 tcatgattcc ttattattta tgggtactat tcgcaactct attgaattat tcaatttatt
    21541 ttttaaacta agcgctaaaa agagacgtcc tgtaatttaa cacatagaaa aagtgccacc
    21601 taagttagat tttttgtcta atttaggtgg cactctttat taaccaaact atttttttct
    21661 agtacccact tgttgttcca tactcattat tctggtcata accataacca ttttgttcct
    21721 gtccagcgta aggatcataa ctttgagtat cttgacttgg tgtatagtac tgacttgtat
    21781 cttctgtttg ctgataatag gtattcggat cttggtactg atcatatgtg ttttctgaat
    21841 aggaagaata atcggtgtac ccttcactat tcgatccatc accgtttgtc gaatcgccat
    21901 cttccgaatc atcaaagaac atcattgaag cattctcatt tttcaaatta ggtaatgtat
    21961 cgcttgtttt tatatttaat tgtttcttca gttcattttg gatcgaaaga agatcatttt
    22021 ttcctaaaat ttgatagtag atatcattga tcatttgtcc ttcgccttgc aactggtctt
    22081 gtttgattgt ttcaaacgcc ggggtgtagt tcgtcgctac atcaagcatg tcatcccaat
    22141 ctaagtccgt cgtcacattg ttctcaactg cttttaaaat ttttctataa ttgcttacgc
    22201 catctaaact taaaacttta ttgacgattt tcgtcactac ttcccgctga cgacgttgtc
    22261 gaccgatatc gccttctgga tcttcgtgtc gcattcgaga ataggctaaa cctttttctc
    22321 cattcaatgt ttgttcacct actggtacat ggacaccatc caaagtaaag tcaattttat
    22381 tattcacttt gatgccaccg accgcattga tcaaatcttc catgccatcc aaattgatcg
    22441 ttacataatg atcaatagga atatcgagca gttgctcaat tgaatccatg gccatttcga
    22501 caccaccaaa tgcgtaggca tgatttaatt tatctaccgt tccataacct acgatattcg
    22561 tataaatatc tcggtccaaa ctgatgatcg ttgatttttt ttgtttcgga ttaactgtta
    22621 ctaccatcat cgtatcagaa cgtccttgtt ccgttcttcc taatccaccg gtatctaaac
    22681 ctaatagcaa aaccgaaaaa ggttctttgt catcaatgct tactctctca gaacgtttgg
    22741 aggatattcg attagagttt ttagaaattt tgtttactgt ttggctcgct tctcccataa
    22801 atctgattcc gtatgctgat aatccggcaa tcagcaaaac gaatacccct aacaaggtta
    22861 atagaacttt ttgccatcgc ttcataatac acctctgttt cacattttct aaaatattgt
    22921 ctcatataac tgttcaatca gcaaattcac tttttaatca taagaaaact ttaaaaaaca
    22981 tttttgtgta acgattatta ttttttaaaa tttctcaaaa ttcttaacta tcataccata
    23041 ccgtgaaaaa gatcgaaaga ccgaatacac gcagttcgca atcgttttat ctttttttat
    23101 gtattttttc cagaaaaagc gaacaacaag gtattttcca aataatcgtg cagtaaaatg
    23161 atcgcacata cctttcccat ctttttaaca gtctttgcct accgttcaga ttatcattcg
    23221 atttcacgac aatttcttcc tatgactggt ccttttgtta aacccatctt ctattcgttt
    23281 tatttccagc tcactgcatg gctcttaaaa tgactcgaac tagtgattgc attaccatca
    23341 tcttttaatg gatagatatg ctcctcttca aagtaaaacg attttctttt aaagtaatag
    23401 aattgacatg gtaatgagta tgtatactag tggtttcaca aatggtcttt tattcaacat
    23461 ccaaaaactg aaatttcttt aaaatccatt actaacgaag aaaatgttcc ttgcttgata
    23521 attagttagg acatgtcaag tgaacaaatg catttactta gccaaaaaat ctaaaaactt
    23581 cataaataga caaaaagaca cgactctcta agaagtcgtg tctttattca acaaattatt
    23641 ataatttagt cacttcagca gcttgaggtc cgcgtgcacc ttcaacaatc gtgaattcta
    23701 cttcttgacc ttcttctagg ctcttgaagc cgtctccttg aattgctgag aaatgaacaa
    23761 atacgtcatc tccgccgtct actgtaataa acccaaatcc tttttcattg ttgaaccatt
    23821 taaccgttcc gtgttccata aatgtatatc ctccaaaaaa gttcttgcaa gtaaccttgc
    23881 aagaacatta tacccaattt agaaaacgct agcaagcttt cgctctttta ttttccaaat
    23941 tatttttaag actgatatga cggaggaaat ggttattttg ctgcttcgaa acgtttgttt
    24001 acttcatccc aattaataac attccagaat gctgcaatat aatctggtcg gacattttta
    24061 tatttcaaat aataagcatg ttcccaaacg tccaaaccta gaattggtgt ctttccttcc
    24121 atcaatggag aatcttgatt tgcagtagag gtaatagcta attttccatt ttccattaca
    24181 agccaagccc atccagaacc aaatcgtcca gcggctgctt ttttgaattc ttctttaaaa
    24241 gaagaaaaat caccaaaagc ttcattaatc gcttctttta tttctcctgt aggttcgcca
    24301 ccagcatttg gtgccatgat ttcccagaaa aatgaatggt tagcatgtcc gccaccattg
    24361 ttacgtacag ctgtcttgat atctgttgga atagcgtcca tatcagataa taattcttct
    24421 attgtttttt cgcctaattc tgggtatttc tcaattgctg aatttaaatt cgtcacataa
    24481 gtattgtgat gcttatcatg atgcagatgc atcgtttctt cgtcaatata aggttccaat
    24541 gcgtcatatg cataaggtag atctggtaat gtgtaagtca taaaaaaatt cctcctcaat
    24601 gttttcttaa taatgtctac attacaaaga gtaacaaaga gaaggaaatt cttcaattgt
    24661 tatgcctagt cgtctttttc actttgacct acttcttctt caaaaacctc agtttcttta
    24721 aaaataaaca acttgctgaa aatatagttc gcaaggataa caataatttg agtgatgatt
    24781 ttcgccacat actcattgct gttcataaca ttgatcaaca ataccattgc ccccatgtcc
    24841 aatccgtaag aaaggatacg gtagaagaag aacttaccgc attcaataag tgcatgtgta
    24901 aaattcggtg attttgaatg gaatacccaa agtttgttcg ttacaaaagc aaacaataca
    24961 gaacaaaacc acgaaataga attggataag gccatactta aatcaaaata ttggcgtgcg
    25021 agagcaaaac taacaaaatt tacaatcgta gccaaaccac caaaaaagag atagactagt
    25081 atctcccaat atccttttgc ttctaaatat ccttttaact gtcgatactg cttcatgagc
    25141 caacctacct tattaaaaat tcttatttat catactctat atttcaataa ctttcatctt
    25201 tatttaaaaa aattaatttt ttttgatcct ttgcctttgt ctctgcttgg atcgtcacat
    25261 gtgtaatacc atattttaat tttaataaag aaattatacg aggatatatc ttttcaatct
    25321 cgcttagtag ctgatcttca aaatcaatat gtccgtcgaa aataattatc ttttcgctat
    25381 actgccaaat atggacatga tgaacatcct ttaccccatc gattgcttca atttcttgtt
    25441 ccattttttc atagtcgata gcaggtgcac tttgtatcaa aatagcggca gcttttttga
    25501 tcaccattat cgcttctatc aatatatata tcgaaatgat cagtgtaata actggatcga
    25561 tccagtagat atcgaaaaaa cggatcaaaa ttgctccgat aatcacactt accgaagaca
    25621 gtgtatcact taacaaatgc aaataactag attttatatt caaactttca tctgcttctt
    25681 gtcgtaataa taatactgag aacaaattcg cgagcaatcc aataactgct actgttagca
    25741 tcaaatgact atttatcttt tctggtgaag tgaaccgctt gaatgcttca acggttaaaa
    25801 acaaggataa tatgatcaat atgaatgagt tgatgaaagc actcaatatt tctaaacgct
    25861 ggtagccata cgtacgtttt ttatttgctt cttttcgggc cattttttgt gccccgtaag
    25921 aaaaaataat tgccaatgta tcactaaggt tatggaaagc atctgaaaca agagacaaac
    25981 tccctgacat aatccctcca ataaattctg ataaagtgat caccgcattc aaaaccacta
    26041 ctccaaatag tttttttgat gatctctgtg gctgtgtagg cactattcct tcctccattt
    26101 tatttatatt ggatagtctt tagacaagaa taacattttt ttgatatttc accaatcatt
    26161 cagctgtttc cttaaagcac ttgtatttca cttgatactt cgctagaatt gcaagtgatg
    26221 acactactag atgaggagta cttatgacaa caaaacaatt aattatcagt tcctttatac
    26281 gattcaaaga cctaaaggag gcgagaaatg tcccattttg gaaagccatt gtctatcttt
    26341 tagttttgag tataattatg gctttgccaa tctcttttca agtttttcaa gtcttaaaca
    26401 acattcaatt ggatgggcaa aagattgcta ctcgcattcc tgattttaca atccaaaacg
    26461 ggcagcttca aaccgaagaa aaagaaggat tcatttacca aacaaactcc attatcttca
    26521 catttgatcc agagggaaaa cgaacagaac aggacatctc tactgatttg atggggaatt
    26581 ttgttagtgt cgggatgtta aaaaacaaac ttatcatagc tcttcctaat acaggcacga
    26641 cttctgcttt gttgaacaat aaccaattag aacttcccta caccaatgaa tctttaaaaa
    26701 acttaacagg taagcagctc cgttcttttt taagtgaagc atctatacca ctttggataa
    26761 aagtcctgac atttatattt tctatttatc ctagttttct gaatctgctg atcactttgc
    26821 tatttaccaa cattgctgct tttctctatg cacgctttcg actaacaaaa gctacttttc
    26881 ttgattgttt aaaaacattg atctattcaa tttcattgcc tactataatt gcaacaatct
    26941 tgatggtctt tcttccttct tttgacacta gcgccttcat tgcttttgca ggaatcttta
    27001 tttttgctca agctgtcaaa ggatgggcaa aaatatcgat caattaagaa ataaagacaa
    27061 ctcgttattt ctacttcaat agaccctttt agaggttgtg acattttttt gtcacagccc
    27121 cttttttatt tgaaaaatat ttctttctca aaaaacaagc aaggcgcttc aaagttcttc
    27181 ttgtatgcgc tacacttaga gtaaagaaag gcgggaaatt aactatgtca gaaagaatca
    27241 tttatgcaga tcgtccattt cgtgatgaat ttatcgaaga aatccatact atagcgcctg
    27301 gttatatctt taaaacagaa ttacaaccag aggatctaca aaatgtagag atcagtttgg
    27361 gctggaactc agactaccaa gaaaaactat tagcctcttc taccttgaaa tgggtccaat
    27421 ctatctcagc tggtgttgat cagctacccc ttgagacttt ttcaaagaaa catattttac
    27481 tttcaaatgg tagtggcatc cacagtgaat cgattacgga gcatgtctta ggaatcatcc
    27541 ttgggtattc tcgtggtctt tttcaagcac aaaaggcaca gagtgacatg aaatggttag
    27601 gttcatcggt ccattaccaa tctatccaag ggaaaaaaat actaatcatt ggaactggcc
    27661 atattggaaa aatgattgca aaaaaatgca aagcattaga catgaactgc tatggaatca
    27721 atacatccgg tcatccagca gaaggaatgg aaaagacttt ttctttaaat caactaaagg
    27781 aagttcttcc tgaagtagat ttcgtagtca atatcttacc tctaacggag gaaacaactg
    27841 ggctctttga tcagcatatg tttgaacact ttgatccaaa atctgtattc atcaatgttg
    27901 gccgtggtgc ttctgttaag acacaagatc tggtgcaggc tttaaataac cagcaacttt
    27961 cctttgcagc attagacgtt tttgaggaag agcctcttcc acaagatcat cctctttgga
    28021 aaatggacaa tgtactgatt acttcccaca ttgcaggttt gacacctgat tttcaaaaga
    28081 aattaatggc tattttttta accaatctga aaagctactt tgccacccat gagcttcaaa
    28141 ccaatcaagt aaaattgtct gcaggatatt aatagctgaa aacaatattt tcaaaagaaa
    28201 aaagagaagg tgacaaaaat tgtgtcaccc tctctttttt tattgttttt taaagtgata
    28261 ggttggctcc tccaggttgg gattataatc aacaagtaaa tcatatcctt taaagaacca
    28321 ttcatctgct tcctcgataa aaaaaagtgt cccatcaatt tccactttct ttacaggatg
    28381 ttctggctgt tcaactgaca ttccaatcga aaaaccatca tgaacctctg ttttgccgta
    28441 gacttttcca aaaaaacgta ttccgtaagt ttctggcaga tcaatttctg agtcaaacca
    28501 cttttgtgct tttggcgtta ccgttaattt catcccaaca acctactttc tcttttcttt
    28561 ctattgattc atcttatcgt ctagaatatc cacatcgcct gtctctccaa taaccagtag
    28621 attatcattt tcacgaacat attcatctgc tgcaggagaa gcgataaccg tttgatctac
    28681 tcttcgtatg gcgactactg ttaagtcaaa acgttgcctg aaatttaatt cagctaatgt
    28741 tttgttgaaa aatttaggat tggagactcg gatttctgct aaagaatatt tatctgacaa
    28801 ctctaggtaa tctaaaatat tctttgacac taaattatgc gcaatcctta ttcccatgtc
    28861 tcgctcggga tggacgacgc gatcagctcc gatcttttca agtactctgg catgatactc
    28921 attttgggct tttgctaaaa tatttggtac gcccatttcc tttaccatca gagtaactaa
    28981 gatactggct tgaatatctt ctccaatagc gacaattaca tgatcgaaat ttcttatgcc
    29041 taatgatcga agtgtcattt catcctgtgc atttgccaca acagcatgag tggctatatt
    29101 catatattca ttgacccgat cttcattact atcaatagcc agtacttctt gaccagcttc
    29161 gatcagtgtt cggcagatac ttccgccaaa tcgtccaaga cctacaattg caaaattttg
    29221 tttcaccgtt ttcctccttt agtatcttct tttctcagta taacaaagcc tttacaaaaa
    29281 caaaagcaag catcattatt gtaaaaaagc caagaaaaat aatagttatt ttctcagctt
    29341 ttgattatcc tctttatcat cgtttttatt tcaccaaacc atgtttgaat gcatagatag
    29401 cggcttgtgt acggtcttcc acttctagct tagccaatat attggaaaca tgtgttttta
    29461 ctgttttcag tgtaataaac aattcgtccg ctatttcctg attacttttt ccttcagaaa
    29521 tcagcattaa aatttcattt tcccgattcg ttagttcttc atgtaataca ggctcatttc
    29581 gccgactcat tttttccatc atttttgttg tcacttctgg ttctaatact cgctcgccac
    29641 gttgcgttgc ccttatagca tcagcaattt catgtgcggt agaggtcttc aacaaatacc
    29701 ctgctgcacc tgcttcaatg gcaggataaa ctttttcgtc atcaataaaa ctggttacga
    29761 taatgatttt agcttctggc caatctttta agattgcttt tgttgattcg ataccatcca
    29821 tttcttccat gactaagtcc attaaaatga cgtccggtcg aagtgtcatc gccttctcat
    29881 agccttgtcg tccattttca gcttctccaa ttacttcaat gtcttcttga atagataaat
    29941 aaaaagagac gcctaagcgc accatttcat ggtcatctac taataaaact tttatcatcc
    30001 ttatctatgc ctccttcatc aaagggacct tgatttctac acttgtacct tgacctttaa
    30061 aactaatgat ttttactgtt ccaccaatac cagctactcg ttctttgata ttgttcaatc
    30121 cataacttcc cgttttcgtt tcattcatat taaaccctgt tccgtcgtca ataatacgta
    30181 acaaaagatt attgtctatt ttgtgcaaat atacctctaa ttcattggct ttagcatgtc
    30241 ttaatgtatt tgataacaat tcttgaacga ttcggaacaa gtgatcctca atggaactag
    30301 atagttttac atcttctaca tcccatttca gcgaaatctg gattttattt tgcaattcct
    30361 tcaataactg ctcgatacct tgctttaaac ttttctcttc taaattgact ggacgtagat
    30421 gaagaagcag cgcacgcatc tcagactggg aagcgttgat gatctctgct accattttca
    30481 actgcttgcg aaacatttct ggtgtctcgc ttttttctgc ttgctccgtc aatgccgaca
    30541 tcatcatcat tgctgcaaac aattgttgcg aaactgaatc atgcagctca cgggctaatc
    30601 gatgtctttc taattctaaa atttcttctt tggtttgtcc atctacatat tggggacggc
    30661 tcgttacaat ttgtaattca ctagatactt caatcatttt ttcttttatc ttagtgattt
    30721 ccttatcaat atctttgatg tataaatcgt ccgatgcact tgggatcgga agaagcaaca
    30781 atttggattc ataattgcca gaagaaagtg cacgcagctt ttcttcgatt ttcccgtatt
    30841 ttgtcttttg aataagtgat aataatagaa agacaattaa tcctacacct aaggaaatgg
    30901 ctaacaaatg gaagataagc ggaacatata ataaacgtgc acgcagtaat tctccccacc
    30961 aatgactttg attgctggca taaaaataag tgaaaagtga aaatagaata ataaggaaag
    31021 ccgcaatccc cgaataaaca gctagcatcg ctctggatat ttttcccatc atattcgtat
    31081 cacctcgaca tctccaatca aggtattagt aataatcttc aatctacgag ggttttcatc
    31141 ataatcactg ctgtagattt tgatttgttc atttttcaaa gaaaattgct cttcttcaaa
    31201 caagacattt cctactaatg tcgcatgctc taatcggatg gctacgccca aaggtactaa
    31261 gatccgtgtt ctgcctatcc cttttcttac aatcacaata ttatcatctt ttggcaaaag
    31321 cgtattgccc aaatctatga tagtatcacc agaaatgacg gcgatgttga tatcgtccca
    31381 ttcatagacg tcgtttccaa tacgttggtt accgaataat tgctgtcttt tccgctcatt
    31441 attatgtgtt tttaattgct ctgtttggat catcatgatc tgtttctttc gccaaaaagc
    31501 atttttggtt aaatctatcc ctgaaatctc tacacctttc agaccaataa ataaaacggc
    31561 aaatacagcc atcatccata aagcaggact gttgactaag ctaaaaaaaa tgaccaaact
    31621 tcctaatatc aattgaaaat tttgaaattt agtacgagga tgtttgcgca tagctagata
    31681 tatattgaaa ataccgaata tcactaaaag caaaagtcca gtattgttta cgatttgcca
    31741 aacagcaaat aacagcagta gtgcttcaac taccacaaaa aaacgccaag aactattcat
    31801 cgctctttct ccctcctgac acattctcat ttcatcatac ctattttttt aactgttggc
    31861 tataggactt tagatgtaag atcgtttgtt gaaatctaaa atacacaaag agaaaaagat
    31921 ctagagtgta tcatcagtaa gatgaactct ctagatcttt cagtcagact acgcttgttc
    31981 tactttgacg attttaacta acatatcgcc acctggagta gcaatagtta cttcatcatt
    32041 tttacgtttg ccaatcaatg cttgcgcaat aggagaatca ttggaaattt tgccagaaaa
    32101 cggatctgct tcagcgcttc cgacaatcgt gtactcttct tcttctccat ctggtagttc
    32161 gatgaatgta actgttttac caattgatac ctcatctgca tctacaccgt cgttatcgat
    32221 gatttgagca aaacgaatca tattttcaat tgttgtgatt cttccttcaa caaatgcttg
    32281 ttcatctttc gctgattcat attcagagtt ttcggaaaga tctccgaaac cgcgggcaat
    32341 tttgattcgt tcaatgattt ctccgcgttt gactgttttt agttcttcta attctttttc
    32401 taatttttct ttaccttcta gagtcattgg ataaactttc tctaccatgt gtaacgtctc
    32461 cttttttcga taaaataccg caaaaggtaa tcttttgagg aatatagtcc aaaaaagatt
    32521 accacgcttt tcttcaaatg taaatgtttt tctaaaaatg atcaatgtct agagcctgtt
    32581 tttctaagaa ttatttacat atttttccac taattccata tgttcttcat aagttttagc
    32641 gaaataaaca tttccagtgc tcgtatctgc tacgaaataa taatagtcat tttctgctgg
    32701 ttctaatact gccttgattg cctcttcgct tggattgtca aaaggtccag gtccatagcc
    32761 ggtattggta tacaaattat atggtgaatc tacagctgta tcttcatacg tcactaattc
    32821 tttgtgttca cctaatgcgt ataaaacaga gatatctgac tgaagtggca tatttgcttt
    32881 gattcggtta aagaagactt gtgcaatgtt tttacgatca ttttctttta cgccttcttt
    32941 ttcaactaga gaagctagag ttaaaacttc ttgtacagtc aaatttttct gcttgatagc
    33001 tgaataatag ttttgcatga ccgtattcgt cttgttcacc atttcaatca ctagatcctt
    33061 aagcgaagta ctcgtgtaat aatcatatgt ggctgggaat aagtaacctt ccaaacggta
    33121 ttttgtgttc tcagctttag atgcactttc caacagttct gggaattttt ggtgcaactc
    33181 gttaaagaaa gtctcatcat tcactaaatc taaaaattct ttcttgtctt taccagttac
    33241 cttcgctacc cgttcagcaa tctgatcgat atcgtaccct tctggaatgg caattttccc
    33301 atctgcaact tttgttggct cagaagtacc gccttcttgc aactgtttgc caatctcgtc
    33361 aagagtcata ttaggcgcta actgataata gccagcttga aagccagtta aatttttaaa
    33421 ttttgtataa taattgaaaa caatcccgct tttaataata ttgtccttct ccaaaatctc
    33481 accaatctgc ttgttagaag agccactcgg gatctcgact tggactaatt ggtcatctga
    33541 tttatctaaa ggcttcaacc cgctatctac ataacgatac acggtaaatc caagaaatcc
    33601 gccaataatc aataatgtaa gagcaatcac taaaatgatc ttcctcacaa tcttatcttc
    33661 ttttttacgc agatttctcc gcttgtcgat tatatctgct gtagctgcct tactggcttc
    33721 ttttttatct ttacttgggt gttgtttgtt tcctgacaaa acaactcctc cttactatca
    33781 agttcgtaac tttattcatt atacatgata tttgaattgg cgtgaatgat tttatttaaa
    33841 tattctatca aaaatgtaag tagtaaatcc attactataa gattaaaata aatgttatca
    33901 agatacaagc tattttagct ttattctttc tgtaaaaaag aaaggagact aaataaacta
    33961 ttatgaaaaa aggaaaacat gctaaaaaaa gaaaatattc atttttaatg atcgttgtcg
    34021 tgttgtttag ccttagtgcg ttctctacag gaactattct tggatggcaa ttttacaata
    34081 atgaacactc tcagatagtt gcccatgctc aatcagctca aaaaaagttg atactgacta
    34141 ccaatgaaca acagctcgtt gaaaaaatcg atcaactatt aagaaaaaat gattatattg
    34201 gctcaattta cgtaaagaaa aataatcgca tcatcatgga aaaaggctat ggctatgcga
    34261 ataaactcac gcaacaacca aatgatcctt ctctttatta tcagattggt tcggttcaaa
    34321 aagcattgac tactcttttg attttaaaac aagtcgagcg tgggcacctt tctttagata
    34381 ctaagctggc tcaattctat ccacaaattg ctggcagcca gcaaattact atccgtgact
    34441 tgctgtatat gcgctcaggc ttgcaccgaa ctgcttctcc aaccataccg atgactgatg
    34501 aagaagtcgt tcaatttgcg attcagcact taaaatttac agattatcag acctctcatt
    34561 atgattcatt gaactttacc atattgactg gaattttgat caaattaaca aatcaaccgt
    34621 atgaaaaatt attgaccgat gatatcatcg aacctttagg attacagcat acaaaatttt
    34681 atgaccaagt caaaaattca tccaatcatg cactatccta tcaaatgtct aaagaggatg
    34741 attactttaa accactgaca gaatctgaaa cagagatcca taacgaatta gggactggta
    34801 atatcagtat gtccgtctat gatttaaata cgctgtttac acaagtttta tctggaaaac
    34861 tagtttccaa agacttactc ttctcattat ggcgtgaaaa tgcgaatgga catccatata
    34921 gtggtggggt atatagcgga gataattata tcctgtcgca aggaaatatc gactcttttg
    34981 atacatctgc tatatttagc aaagattcac aggatgctat catcatggaa agcaatataa
    35041 aagctgacaa aactatcaaa ctgcctactg ctgatctaag aaaccaaatc tatgacctga
    35101 tggaaggaac tactaagttg gcaaatagct gatatgatga aaagatagca aatactactt
    35161 ctttgaatag catttgctta aaaaaagtac tcgactaaac gtaggaaaga gtgtgggaca
    35221 aatctaaaaa tcaatttttg ctacagactt taattccaaa taaacagaac agaaagaggt
    35281 gttcttcttt ctgttctgtc caaattattc taagatttct ctttaccaac attatttgac
    35341 aaagggccta ttaaatctaa aatagtatct ttagattgct aaaatatgtg ctagcaaatc
    35401 attcatggct tgttcttatt tttaatttta tgcaataaaa aagaagaaca attagcgtga
    35461 ttatagaaat aaataatgag attttagaaa aaaatgtgta tgaatacctg attgttactt
    35521 tatttattcc actttcactt tttactgtaa caaaaggacc tccttgtttt agtactgtag
    35581 cattttttga attaacagta accgttaatc ctttataccg gaatacaggt aaaactattg
    35641 ttttgccttt tgaagattta aacgtaaatg taatttcatc tttatttgga gaaaagctac
    35701 tataaataac ttgaccatct tctgtaactt gatggttttt caaaagcaat tgatcttttt
    35761 tatagcctat aggtacataa tcaaaattct caaattcttc aagtttattt tccatttgtt
    35821 cattagaata agttccttga aaattcattt ctttcaccat gttaactact gatgaataat
    35881 ttaaaa
//
LOCUS       DAFLWC010000017        35677 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.017, whole genome shotgun sequence.
ACCESSION   DAFLWC010000017 DAFLWC010000000
VERSION     DAFLWC010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35677
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.017"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            306..2072
                     /locus_tag="L1V17_000827"
     CDS             306..2072
                     /locus_tag="L1V17_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBN1235611.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            2174..3433
                     /locus_tag="L1V17_000828"
     CDS             2174..3433
                     /locus_tag="L1V17_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBN1235612.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            3580..4881
                     /locus_tag="L1V17_000829"
     CDS             3580..4881
                     /locus_tag="L1V17_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1235613.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            4884..5735
                     /locus_tag="L1V17_000830"
     CDS             4884..5735
                     /locus_tag="L1V17_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1235614.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            5748..6563
                     /locus_tag="L1V17_000831"
     CDS             5748..6563
                     /locus_tag="L1V17_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HBN1235615.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            6714..7880
                     /locus_tag="L1V17_000832"
     CDS             6714..7880
                     /locus_tag="L1V17_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBN1235616.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            8110..8757
                     /locus_tag="L1V17_000833"
     CDS             8110..8757
                     /locus_tag="L1V17_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBN1235617.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            8841..9785
                     /locus_tag="L1V17_000834"
     CDS             8841..9785
                     /locus_tag="L1V17_000834"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HBN1235618.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            9920..11371
                     /locus_tag="L1V17_000835"
     CDS             9920..11371
                     /locus_tag="L1V17_000835"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HBN1235619.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            11392..12228
                     /locus_tag="L1V17_000836"
     CDS             11392..12228
                     /locus_tag="L1V17_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBN1235620.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            12228..12887
                     /locus_tag="L1V17_000837"
     CDS             12228..12887
                     /locus_tag="L1V17_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBN1235621.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            13013..13702
                     /locus_tag="L1V17_000838"
     CDS             13013..13702
                     /locus_tag="L1V17_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235622.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            13708..14664
                     /locus_tag="L1V17_000839"
     CDS             13708..14664
                     /locus_tag="L1V17_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HBN1235623.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            14708..15220
                     /locus_tag="L1V17_000840"
     CDS             14708..15220
                     /locus_tag="L1V17_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1235624.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(15476..16024)
                     /locus_tag="L1V17_000841"
     CDS             complement(15476..16024)
                     /locus_tag="L1V17_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1235625.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(16113..17294)
                     /locus_tag="L1V17_000842"
     CDS             complement(16113..17294)
                     /locus_tag="L1V17_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HBN1235626.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(17530..19038)
                     /locus_tag="L1V17_000843"
     CDS             complement(17530..19038)
                     /locus_tag="L1V17_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBN1235627.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            19197..19388
                     /locus_tag="L1V17_000844"
     CDS             19197..19388
                     /locus_tag="L1V17_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235628.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            19591..20508
                     /locus_tag="L1V17_000845"
     CDS             19591..20508
                     /locus_tag="L1V17_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HBN1235629.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            20501..21574
                     /locus_tag="L1V17_000846"
     CDS             20501..21574
                     /locus_tag="L1V17_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235630.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            21722..22240
                     /locus_tag="L1V17_000847"
     CDS             21722..22240
                     /locus_tag="L1V17_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235631.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            22221..22613
                     /locus_tag="L1V17_000848"
     CDS             22221..22613
                     /locus_tag="L1V17_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HBN1235632.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            22689..23624
                     /locus_tag="L1V17_000849"
     CDS             22689..23624
                     /locus_tag="L1V17_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HBN1235633.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            23757..24536
                     /locus_tag="L1V17_000850"
     CDS             23757..24536
                     /locus_tag="L1V17_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBN1235634.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            24529..24846
                     /locus_tag="L1V17_000851"
     CDS             24529..24846
                     /locus_tag="L1V17_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBN1235635.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            25090..26700
                     /locus_tag="L1V17_000852"
     CDS             25090..26700
                     /locus_tag="L1V17_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBN1235636.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            26857..27705
                     /locus_tag="L1V17_000853"
     CDS             26857..27705
                     /locus_tag="L1V17_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBN1235637.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            27936..28415
                     /locus_tag="L1V17_000854"
     CDS             27936..28415
                     /locus_tag="L1V17_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235638.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            28448..30676
                     /locus_tag="L1V17_000855"
     CDS             28448..30676
                     /locus_tag="L1V17_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1235639.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            30805..32448
                     /locus_tag="L1V17_000856"
     CDS             30805..32448
                     /locus_tag="L1V17_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBN1235640.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(32521..33066)
                     /locus_tag="L1V17_000857"
     CDS             complement(32521..33066)
                     /locus_tag="L1V17_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HBN1235641.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(33089..33574)
                     /locus_tag="L1V17_000858"
     CDS             complement(33089..33574)
                     /locus_tag="L1V17_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBN1235642.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(33564..34376)
                     /locus_tag="L1V17_000859"
     CDS             complement(33564..34376)
                     /locus_tag="L1V17_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HBN1235643.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(34515..>35677)
                     /locus_tag="L1V17_000860"
     CDS             complement(34515..>35677)
                     /locus_tag="L1V17_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBN1235644.1"
                     /translation="NFEIFFRILKLTSTTGIPILYLMEQPALSVSQSFLDKNEISYMT
                     HTSGTTGIPKLICHSAHSMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLM
                     SMGFPMMPLANAQSSKVVHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHS
                     TFDAINNQTMKTFLRTSMAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGL
                     EDMTSARITDSVGNVLPENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGF
                     MDKHGHLFLKDRQVDLIETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAP
                     DKEMDWNRWWEQVHELPRLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT        11676 a         6418 c         7125 g        10458 t
ORIGIN      
        1 aaattaggct agtctaaatt attatgtttc attcttctag aatatacttc tacgccaaaa
       61 actgttaaaa aacttttact ttagaaaatt ggagaaattg atcgcttaag ataaattcag
      121 gacactaaat agtacaggaa gtagactaaa acttttaaaa gttttaagtc tatctatttg
      181 gcaagtttaa aaaataaaaa ttcggtatca aaaaactgtt accgataaca tttttgaaag
      241 cgttgtcttt tgcttctcta tcacttatag tgatgacgtc atattaaaac acaaggagga
      301 aatcaatgga tacagctgca atttatcatc gaccggaaag tgaatatgca tttctatata
      361 cgaatacaag atttcgtatt cggcttcgta ctaggaaaaa tgatatcaaa aaagtatatg
      421 tgctatgtgg agatccatat accataacaa ctgaaaaatg gtatcaaaaa caacgaccaa
      481 tgaaaaaatg tctaagtacc aatgttcatg attattggga aattgaagtg acgagcgaaa
      541 caagtcgctt acagtatgcg ttccatgttg ttggggaaga taacacggac tgtttttacg
      601 gtgatcaagg aatttttcct tatcgagaaa atgtgattac tgaaccaaat ttttattttc
      661 gaatacctta ttttcatcaa atcgatcgat tcactattcc agaatgggta aaagaaacag
      721 tatggtatca aatttttccc gaaagatttg caaacgggga caaagcaaat gaccccgaac
      781 acactttacc ttggggaagt aaagatccag accgagaaga ctttttcggg ggagatttgc
      841 aaggtgtgat ggatcatttg gattacttga cggaccttgg catcaatggc atctattttt
      901 gtcccatatt taaagccaca tccaatcata aatacgatac gattgattat tatgaggtgg
      961 atcccgcttt tggcgataaa aaacttttaa aaaacttgat tgatgaagca cataaaagag
     1021 ggatacgtat catgttcgat gctgtattca atcatatggg tgtccattca ccacagtggc
     1081 aagacgttct caaaaacgga gaaaaatcga tctataaaga ctggttccac atccgttttt
     1141 tcccagtaga ttcttatcag atgactgact taccagaaac tgctgaaaat atcccatatg
     1201 atacttttgc ttttactcca ttcatgccga aactaaatac agcaaatcca gaagtgcaaa
     1261 aatatttgct ggatatcgca acttattgga taaaagaatt cgatattgat ggatggcgtc
     1321 ttgatgttgc taatgaagtc gatcatcatt tttggaaaaa attcagagaa gcagttacag
     1381 aaatcaaacc agacatctat atccttggag agatttggca ttcctctcaa gcttggctgc
     1441 aaggggatga attccatgca gtgatgaatt atgcatttac agattcgatt aaagattatt
     1501 ttgcaaaaaa gaaaatcaca gcttcacaaa tggtcagtgg aatgaatcat cagcaaatgc
     1561 tttacagaga tcaggtgaac gaaggaacat tcaacttatt agattctcat gatactgcca
     1621 ggatcttgac cctttgccaa ggtaacaaag aattgatgaa gtctgtgatg gcctttatgt
     1681 ttcttcaaaa agggtctcct tgtatctatt acgggacaga aatagggatg actggtgaag
     1741 atgacccgga ttgccgcaaa tgtatgatat gggagaagga ggaacaagat ctagagctat
     1801 tcggttttat aaaagaactt gtttctctaa ggaaacagtt gtctaagatt atttctgaag
     1861 gttctactca gtggctaata gtaaatgatc gtgaagataa gctctatttc acacggaaac
     1921 tagagggaca gatcatctat gtttacttta atcagtcaaa agaaccttgg gtagtagaac
     1981 aggaaaatga ggtgattctt agtcaaaatt gtcagttgtt agaagacggg aaagcagaga
     2041 tacgacaata cggatttttg atcatgtgtt gaaaactgtt accggtaaca acaagaaagc
     2101 gtttgcaaat gaagatttgt gcccattata ataagggtgt aacagcacgt tgaatacaaa
     2161 ggaggaaatg aagatgaaaa aaagaagtgt gaaacagttg ggtttagggt taatctcttt
     2221 aggaatctta ggcggattag cggcttgtgg caatggtaac tcttcagcag aaggggaagc
     2281 cgatgaagga aaaacgttaa cagtttccgt tgattctgga tataaagatt atataaacga
     2341 aataaaaaac actttcgaaa aagaaaacga tgtgaaaatc aagctagtag aaaaggacat
     2401 gttcgatcag ttggaatcat tagcgttaga tgggcctgct ggaaagggac ctgacgttat
     2461 gatggcagca tatgaccgga tcggtgcgtt aggacagcaa ggacatctgg cggaagtaaa
     2521 actgggaaat gaagcagctt acgatgaaac agacaaagcc caagtgactt atgatggaaa
     2581 aatctacgga gaacctgcag taatcgagac ccttgttttg tactataaca aagatttagt
     2641 cgatacagca ccatcaacgt ttaaagattt ggagaatcta tccaaagaca gtcgttttgc
     2701 ttttgagtca gaagcaggaa aaaatacagg atttttagct aaatggactg acttttatta
     2761 ttcctatggt ttaattgcag gttacggtgg ctatgtattt ggtgatgatg gcacaaatcc
     2821 ttcagatatc ggtttgaata atgcaggtgc tgtagaagga atctcttatg caacagattg
     2881 gttcaaaaat gtttggccaa agggaatgca agacataaaa agtgcaggag acttcgccag
     2941 ccagcaattc atgtccaata aaactgcagc aatcattgac ggtccatggc aagcgcaaac
     3001 atacaaagaa aacaatatca attatggtgt agccaaaatt cctactctaa ataatggaca
     3061 gccttatcaa ccgtttggcg gaggaaaagg atgggtagtc agcaattatg ctaaaaacaa
     3121 agacctctct caaaaatggc ttgattatgt aacgaatcag gaaaatcaag aaaaattctt
     3181 tgaaatggta aatgaaatcc ctgcaaacca acaagctagg gaaacagcaa aggctaaaaa
     3241 cgatgaatta acaacagctg tgattgaaca atatgaaaca gctcaagcga tgccaaacat
     3301 cccagaaatg ggcgaagttt ggacaggtgc agaaaacttg atgttcgatg cagcatcagg
     3361 ttcaaaaaca ccaaaagaat ccgcagatga agcagtaaaa acaatcagtg aagccataga
     3421 acaaaaatac tgattaaaat gataaccgtc catttttata aaaaatggaa caggtgcttc
     3481 agataaaagt ggcaagagcg agatggaaaa ttatcttgct cttgttgcca ttatcttaaa
     3541 agcagtttgc ggtttagcaa gtttagaggg ggcattcaga tgcagcaaga taaaacaagc
     3601 aatatcaacg aaaaaaaaat cacgctttgt tcacttattc cagggatggg gcagtttgta
     3661 aatggccaag cttttaaagg tatcgttttt ttcgccatat tcgtcctatt cattggtcag
     3721 atgcttctgg gcggatttca tgcattggta ggattggtta ctttgggaag tataccaatg
     3781 gaagatcatt cattatttat tttgattgaa ggcactttgc aattcatcat tacaatcatt
     3841 ttcttgattt tttacggttt gaatctttta gacgcttatc gagtagcgaa gatgcgtcaa
     3901 gagggcaaaa aaatcaatcg gacgatgaag gaagtcatac ataatatagg tgatgaaggt
     3961 tttccttatc tattgacact tcccgcttat cttctcatga tttttacgat cattttccca
     4021 gtcctagtta cattgttcac tgcatttact aattatgact tcaatcatat tccaccagcc
     4081 agtttaattg attgggtagg ggctaaaaac ttttttagta tcttcttttt aagctcatat
     4141 cgtaatactt tttttgcagt cttttcgtgg accgtgattt ggactttatg tgcaacaact
     4201 ttgcaaatca cccttggtat tctcacagcg gttgttgctc accagaaatt tattaaattc
     4261 aaacgtattt tcggtatcat tttcttatta ccatgggcgg tcccagcttt tattactatc
     4321 atgagttttt cgaatatatt caacgatagc gtaggtgcca tcaatactca agtgattcct
     4381 ttcataaacc agcttccttt tgtagatatc agtgcaatct cttggaaaac ggacccgaac
     4441 tggacgaaag tagcaattat cttagtgcag ggctggttag gatttcccta tatctatgtg
     4501 atggttacag gaatcttaca atcgatttca gaagacttat atgaagcagc aaaaatcgac
     4561 ggagcaaatg catggcagcg cttttcaaac atcacgcttc ctgctgtctt cctagtggca
     4621 gcgccaacat ttattacaca gtatacgggg aatttcaata atttctccat gatctatctg
     4681 tttaacaatg gcggtcccgg aagcgtaggc ggaggagctg gttctactga tattcttatt
     4741 tcctggatct ataaacttac gactggaact tctccgcagt attctatggc ttcagcaatc
     4801 acgttgatta tctccgtcat cgttatctgt gtgtcattgc tggtatttaa aaagacaaat
     4861 gcgttcaata tgggggatta acaatgaaaa aatttcattc gagtgctcga ttccaaaaac
     4921 gactttctca cttttttact tacttttttc ttttaatact gtcagtcatt atcatctatc
     4981 cgcttttgat cacagcaagt actgccttca agtcaggaaa tattgcagct tttagtttag
     5041 atctttcaag tgactggact ttaggaaact ttactcggct attcagtgaa acactttacg
     5101 ggacttggta taaaaataca ttgatcattt ctgtcctaac aatgatcgta caagtgactg
     5161 tagtaacttt ggcgggctat acttatagtc gctatcgttt tatcggccgc aaatcaagtc
     5221 tgatgttctt tttagtgatt cagatggtac cgactatggc agcattgact gccttttatg
     5281 tcatggcttt cttattagaa gcgctcgata agtactggtt cttgacaatg atctatatag
     5341 gcggtggaat tccaatgaat acttggctga tgaaaggata ctttgacact gtaccaatag
     5401 atttagatga atctgctaaa cttgatgggg cagggcattt caggattttt ttccagattg
     5461 tattaccgct tgtcaaaccg atgctcgccg ttcaagcatt atgggctttt atgggacctt
     5521 ttggggattt catgttagct aagttcctgc ttcgaacacc tgaaaatcag actgttgctg
     5581 tcggcttaca aacatttatt tctgatgtga caaaccaaag agtctctctt tttgctgctg
     5641 gggcaatttt gattgcacta ccgatttgtc tattattctt ctttttacaa aagaactttg
     5701 ttaccggcct gacatctggc ggaacaaaag gataggagca gagtatcatg caaacatttc
     5761 cgttaaacta tttttccgca ttacgtacgc caactcaagt gtttgcggga cgcaaactat
     5821 tatcatggcc taaatttttc ttgatatttg tatttttagt ttccttgatg gtcatgcctg
     5881 tgactctttt ttatgccaat cagatccaag cgattccatt agaacaattt ctatccgttc
     5941 attcgctgat cgatgaacaa ggaacccaaa aattttctga acttgaatta tctgaaactg
     6001 ggttacaagc atcgcaacaa acgatagctg tgacccctga aattttggta ggtgtgtctt
     6061 tatctgagaa acaacaatcc gatcatggaa cttttattga ttttgagaag gaacaatggg
     6121 tgatccaaca aaaggataaa tctggtatac gccgctatac gatgaattat agcccatctt
     6181 tccaaccaga ttctgtacgt acgcccgaag atttccaacg atttttagaa agagaatttt
     6241 atgccagtaa tcgtccaaca atcattttat cttatagttt aagtcttggt cttgtcctat
     6301 ttgtcatgac gagtctcatt ttattcgggg cttccttttt cttgtggatg acaagaaaaa
     6361 gccaactttc atccattcat acattcaaag agagtgcaaa tttgatgctg aatgttatgg
     6421 gaataggttc catggcagca gcagttgtag ggtttatcca ctttgacttt atcttgatgc
     6481 taagtgtcca aacaacgata actgtcttgc tgcttttatg ggtttttgtc aaaacaagat
     6541 tcaaagataa gcgtgtcgaa tgacaagttt aagcgattta tgcgacaatg aatgtgaaaa
     6601 aaatgaaaaa taaagtagtt tttgaaaaat ttctgaaaaa attaaacttc ttagttgatt
     6661 cttttctttt ttagtattaa cgtaataggg tagttttttt aaggaggaaa atcatgttag
     6721 agaaaacttt atacaatcaa ttattttcac gttctttctc gctccctgtc gaagtaaatt
     6781 attgggacgg tacaacgaaa caatacggag atacggacac tcctccccaa atcaaaatca
     6841 atatccatga agaaatccca atgaaagaga ttacaagtaa cgcatctttg gcactaggag
     6901 aagcctatat ggatcatcga atcgagatcg agggaagtat ccaagcattg atcaacgatg
     6961 cttatcagca agcaaacagc tttttacgag gaaaagatta tctaaaatgg ctgccaaaga
     7021 aagaaaaaca tacgaaacaa aaaaacaaag aagatatcca tgcgcattat gacttaggta
     7081 acgactttta taaactttgg ctagatccaa ctttgactta ttcttgtgct tatttcaata
     7141 cacctgaaga tacgttggaa caagcacaaa tcaataaagt ccatcatatc ttagacaaac
     7201 tctttatcaa agaaggcgaa acgttgcttg atatcggttg tggctgggga acattgatgt
     7261 tcactgctac caaagagtat aatgtcaagg caactgggat cacactaagt gaagaacaat
     7321 acgatttgat taccaaaaga ataaaagaag aacatttaga agataaatgc cgtgtattat
     7381 taatggatta ccgcgaacta aaaggcgaaa cgtttgatca tatcacaagt gtaggtatgt
     7441 tcgaacatgt aggttctgaa aatcttgaag gttatttcaa agtggtaaaa gatttattga
     7501 aaccaaaagg aacagctttg atccatggaa tcagccgaca acaaggcggt gcgacaaatg
     7561 cttggatcaa taaatatatt ttccctggcg gttatgtccc tggtgttact gaattagttg
     7621 ataatattac aaaaaacgat ttgcaactga ttgatttgga aagcttacgt cgtgactacc
     7681 aattgacatt agaacattgg acaaagaatt ttcatcaagt ccaagatcaa gtcacgaaag
     7741 aaatgggtga ttccttctat cgaatgtggg atctatattt acaagcttgt gcagcttcat
     7801 ttgaatcaag taatatcgat gtgattcaat atttgcttgt tcaacctgga aacaatgaca
     7861 tcccaatgca tcgtgcataa ttgaggcaaa agtactgttt aaagactatt taaaaagaag
     7921 ctaagtttta tgatgctcca gaagtgaact tttttgtcta acttctagga ttgtctctaa
     7981 agcttagttt ctttttcttt atattttcat aataaaagtt tggttcttta atttttaaac
     8041 atgacagaaa attttttctt cgttatactt gtaatagaat actattttat aacaaagggg
     8101 atcgaatcaa tgaaaaaaac tgttatttat actagtttat ttgcagcttt gtttttagct
     8161 gcttgtcaat caaataccaa tcaaggcaca tctgggaata cgtcttccag tagcgaacag
     8221 cgctcttcac aggtatcgga ctcctcaaca aaagcaagca catcttcgtc tagccagaca
     8281 aaaagttcta gtgaagcaag tactcagtca gatatcaaag tgtctgcagc tcgtgcgatc
     8341 gaattgttcc aagataaata cccagatact gcaattacta gtttggaatt agatagtgat
     8401 tggggatctt acttctacaa gatagaaggt gtcgatgatc aaaaagaata cgaagcaaga
     8461 attgatgctc aaaatgaaaa aatggagaca gagaatccag aaactctaga tcgagatgaa
     8521 caaaatggtc aaaagaaaaa agaagatggt ctggatgttg ataaattgat cacgattgag
     8581 gaagcagcaa aaatcgccgt cgacaaagta ggaagcggta cggcaacaga ttgggatttg
     8641 gataaagatt taggtactac ttattgggaa gtcaaagtaa aagacggcaa tcaaagtaca
     8701 tcagtcaaga tcaatagcca aacaggcgaa gtactgtcaa ctgaacaaga tgattaagaa
     8761 tttcttcgga aaacaagagt tgatttttct tttagtcatg atacactaga caaaataact
     8821 tgtttgaagg agcgatttac ttgagtttag aaacgacctt tgccaatcat atctttgcca
     8881 atcctttgat gaatgcatct ggtgtccact gcatgactac ccaggaatta gatgaactgg
     8941 ctcattcaga agcaggagca tttatcacta agagctgtac gatcaatgaa cgaaaaggaa
     9001 atcccgaacc acgctatttt gatgttcctt tagggagtat caattctatg ggacttccaa
     9061 acttaggttt ttcttattat ctagagtatg ctcttgcgta tgaaaaagtg caggaaaacc
     9121 aaaatcaacc gttatttttt tccattgccg ggatgagtgt ccaggaaaac ttggaaatgc
     9181 ttgagaaaat agaaaaaagt gggtttaatg ggatcactga attaaattta tcttgtccca
     9241 atgtgcctgg aaaaccacaa ctagcttacg attttgaggc cacttatgaa acactgaaag
     9301 aagtattcag catcttttct aagccgctag gaatcaaatt gcctccttat tttgattttg
     9361 ctcattttga tcagatggct gatatcttga atcagtttcc attgacctat gtcaatgcta
     9421 tcaacagtgt gggcaatggt ttgtatatcg atacagaaca agaagcagta gtcatcaaac
     9481 caaaagaagg gttcggcggc attggcggag agtatatcaa gccgactgct ttggcgaatg
     9541 ttcgcgcttt ttatacacgt ttgaaaccag aaatccaaat cattggtaca ggtgggattc
     9601 ggacaggaca agatgcattt gaacatctgc tatgtggcgc aagcatgtta cagattggta
     9661 ccgagcttca taaagaaggg ccggaaattt tttctagaat cataaaagaa ttaacgcaga
     9721 ttatgtcaga aaaaggatat acgtcaattg acgaatttaa aggcaaatta cgcaccattt
     9781 catagcaaag agacgaaggt catgattgat cttcgtcttt ttttataaaa aacactcgtc
     9841 tgttcattcc tgtgcaagcg tactcattgt atgttagacg aacttgtggg aaaataacag
     9901 aggcaaaaag gaggataata tgaatgatgc aacagaatta gcaaaagagc ttaaagaaaa
     9961 agaatttagt tttcaagaac tagttacgga tatacagaaa aaaataaaga agcaaaatca
    10021 tgaattgaat gcgtttgtcg cgcttgaacc attcgagagt aattcccacg agctattgat
    10081 tccccagtca gaaaaagggc cattggctgg tatcccattt cctttaaaaa tgctcggtca
    10141 agaaaaaaag ggatggctag ctacttcagg atctcgttta tttgaaacac accgagcttc
    10201 tcatacatct aattatgtgc ggcaagcaga agcgataggt ctagttcctt ttggacaaac
    10261 caatgcgcca gagtttggtt tcaaaaatat tacagaccca gtcatctatg gcccagcaag
    10321 aaacccttgg aaccttgaat gtacaccggg cggatcaagt ggaggagctg ctgctgcagt
    10381 ttcatcagga atcgttcctt tagctggtgc tagtgatggc ggtggttcta ttagaatacc
    10441 cgcttcgttt tgcggattga ttgggctgaa accttcgcga gggacgatgc cagttggtcc
    10501 atatgcttgg agaggatggc aaggagctgc tattgatttc ggcttgacag tttctatgag
    10561 agacacggag gctttatttt atgggatgag aagtatccat tccggtgcgc catatcaagt
    10621 atcgccagtt gagtggcaaa cacatccaag aaaaaaacgg ttgaagatag ctttttgtgt
    10681 tgattcaccg atccactcac agattagtga agaggcagta cttgctgtaa aaaaagctgt
    10741 agatttcctt ggaaaagaag ggcatgattt gacagagatt ccttacccac tagatggtcg
    10801 taaactgatc acgtcttatt atcagatgaa tggcgcagaa acagcagcaa tgatccgctc
    10861 gattgaaaca ggcatccagc gagctgtcag aaaagaagaa cttgaaccca tttcttggac
    10921 tttgttccaa tatggtcaga agctctctgc cgctacttac atcgattctc tgcatgtatg
    10981 ggatgaagca gcaattgtca tggaaaacct acatcaagaa tacgatctat tcctttcacc
    11041 aacgactgca tttaccgccc ctaaaatcag cgaagatttg caaagtgatg cgataagagc
    11101 acagatggaa cacatcagtg attgttctga agtagaaggt ttagacgttg tttcttccat
    11161 gtttgaggag agcttgaaga tcacacctta tacacagttg gctaatctga ctggacaacc
    11221 agcaatcagc ttgcctactc atttgacaaa agaaaacatg cctctaggaa tccaatttat
    11281 ggctgccaga ggaagagaag atttgctatt tcaaatcggc tatctatttg aagcaaatca
    11341 tcagttccat ttaccaaatc catggaaata gcagaaacaa ggagaagaag aatgaagaaa
    11401 aaaagattgt ttgctctaat aactagtgcc ttttttattt taagcgcttg cggtacagct
    11461 gccgctaatc aggaagataa cagctggagt aatgtagaaa aaaagaaaga attagtagta
    11521 gcgacttctg gcacactgtt tcccgcatct tattataatg atcaaaatga attagttggt
    11581 tatgatgtag atttggcaaa agaggtggct aaacggttaa atgtcaaaat ctcctttaaa
    11641 gaatacaacg tggatggaca aatcacttct gtttcaaaaa gagaatcaga ttttgctgcg
    11701 aacgattttg gtatcacaaa agaaagagaa aaaaaattct ccctttcaga gactttcaaa
    11761 tattcatttg acagtatgat cgtacgaaaa aaagatgatt caggaatcca ctcacttgaa
    11821 gatcttaaag ggaaaaaagc agctggcgaa cccaatacta gctatatgcg tttagcggaa
    11881 aaacacggag ctaaattagt cacatatgac aatgccacga atgatcagta tttaagcgat
    11941 gtagcaaatg gtcgaacaga tgttattcta aatgattatt atctgcagaa aatggccgta
    12001 tctgctttac cagatatccc tgtaaaaata ctggagaacg tttatttcaa tgaaaacgaa
    12061 agtggttttt tattgaaaga aggaaatgat gctctgaaaa agaaaatcga tggcgtatta
    12121 aaagagatga aagaagatgg gacgacaaag aaaatatctg aaaaatattt tcaaactgat
    12181 gtttcagtca aaccgaaaga aacgatggct gagtcggtga gtgagtgatg tactttcctc
    12241 taattgattt ttccctcatg tggacttcac ttcctttcgt actgcaaggc ttggtataca
    12301 cattagggat tggcttcgtg tcgtttcttt taggaaatct ggtagggttg cttttgacag
    12361 ttttaggtct tttggattgg ctgcctctga atgtatttat tcgtttttat ttatcgttct
    12421 ttagaggcat tcccgcacta gtcctgctgt ttctgttata ttttgggtta ccttatcaat
    12481 taagtgcctt aacggcttca gtcatctgct ttacgattac cagcagtgca tttattggtg
    12541 aaatctatcg aggatcacta gcaggcgttt cttcaggtca gtgggacgct ggtttagctt
    12601 ctggtttttc tttctttggg gtattgaaat atatcgtttt gccgcaagct tttcgaatct
    12661 cagtaccggc actcagtaac gtagctatgg atctagtgaa aggtacttcg ttagcagcaa
    12721 caatcacagt gccagaaata tttcaaaaag caaagatcat aggcggtcgg acattcgatt
    12781 atttttctct ctatatttta gttgcactga tttattgggt catttgtatc gggatcgaaa
    12841 aagtgcaaca gtatttagaa aaacgttcta tgcatcagtc aatctgaaaa atagaaatgg
    12901 tgctagcgtg gctggcacca tttctatttt ttgtttcttg tatattctgc ctagtatttt
    12961 aaaaccattt catgtaaaat gtaaatcgaa aatatgttcg gaggtagaaa acatgaagac
    13021 cccgctaacc atcgaaatag aatcctcgtt ataccaatat tgcatcgagc aaggcggctt
    13081 ggttgtagaa gaagtcacga tgcctgatga ccaaggaatt gtagatacgc ttagctgctt
    13141 gacaaaattt gatggaagcc gagaatggcg atgctatgag ctgaaagtga caaaagcaga
    13201 ttttcgctct acagccaaac tgtcatttgt tggacattat aattattttg ttttaccaag
    13261 taaactatat gaagaagtaa aaactgaaat ccctacagga ataggtgttt tagtgtatcg
    13321 tccgtacacg gttgaagagg agatgcctgc ctctggtaca tttctgattg cgaaaaaagc
    13381 agcaaagaaa gagcttgctg taccggaaga agctttgaca aaccgcttca tggcttcttt
    13441 attcagggaa gtaagaaaag caaagcaaat ggagcgaggc gtaaaatatt ttccaacaga
    13501 tcaattgtac aaagaattga aaagacgttc agaaaatcaa gatccatttt ctaacgaacg
    13561 atattatgaa cggtttttag aggaaatagc tagtcaggca atcaatgagt tgcaagaaga
    13621 agttatcgcg cttcagcatg attatgaata tttgaggcaa caacagcaga tccgtcggtt
    13681 gcctacagag ccattggagt gaaaaatatg tactatcctt atttaagagg aaaacaattt
    13741 gacctattag cattaaaaga agcactgtcg cgaggattgc tctccaataa aatccaacca
    13801 gtgatcgaac cagtacgtga ttccgctacg cttaaaaatg tgatcgaatt atttcaaaaa
    13861 aagcaccatc gaatcgctgt gatccaaaat ccccaagtag gacaattcaa attattcgat
    13921 cagcatgtgc acagttggac agtcaaagaa aatagctctg tcgtccctgc acagatctta
    13981 acgccagaaa atctcagtga agtactggat tcacctccag cgtttcttgt tttcgatgga
    14041 cagcactacc caaaagatac agaggtgtgg aaacagttgg caggagttga ttcgaaattt
    14101 ttgataccag atactagtcg ctttcgcatc tggctgcccg aaaacaaaat tgtgatccgt
    14161 gactcttttc aaacgagaaa gcatgttgaa agttatgcag ataaaacaga tgactttttt
    14221 agtgatgact atcttttttt ccacgcagac ggatatattg gattttctga tttcacgatc
    14281 gaaggtagcc gttatttcga taaagggttc cctagccgag cgcttgctat ccatctaacg
    14341 tatattgatg cttacggcaa tatacgcgtg aaacattttg tctctgacag taacgactct
    14401 gctaaagacc aagcattgaa gtttcttgaa gcaggagata aaatgaaaaa atggatcatg
    14461 cgtcaccatc atcaactctt gattacttca ggaatgattg aattattggc tctttaccag
    14521 caacaaaaat tccctggact gggagtgttg aaaaagtggt cacttatgca tcatttggaa
    14581 cttattagtc acctgctaga tcatccaaaa gattggctta aatattattc aaaagttcag
    14641 gaactatatg aagtgatcca atgattagat aatgtaaatg aaaaaggaat agaaaagagg
    14701 aaactggatg tatattcggc aaacaaggaa agaagaagta gaagaagtgg tagaaatcat
    14761 taatgccgca gcggatttca ttgcttcgca aggctctcct caatggcaaa acgggcagaa
    14821 accaacaaaa gaaacgattt tgaacgatat tgaaagaaaa gaaagctatg tattaatagt
    14881 ggaagatcaa attgctggaa cagctgcatt agtctcaagc gtggatcccg tttacacaaa
    14941 aatagatggt agttggaaag aatcaactgg tccttattta tcgattcatc gtgtcgcttt
    15001 agcagaaagt actcgaggaa aaaaactagc aaaaccgttc ttagaacatt tgttgacgat
    15061 tgcagccagc aaaaatatcc aagatatccg tatcgatact tatccagcta atgaaccgat
    15121 ggaaaagacc atctattctg ctggattcac ttatcaaggg atgattgaat ttccttttga
    15181 acacggcgaa agaaaagcat atcaaataat catcaattga ctataaaatc atctgagcaa
    15241 agataaagac attaacacta ctgaaaaaaa caatcatatg atagccaaga ggttgtaaca
    15301 gaagtggcca gcttcaaaaa acaagaaaga atttccgaaa atgcttctca aatttttgtg
    15361 gaattttagc gtattttacg aaatagctgc tttctgaaac tcccttcatc gagaggtcgt
    15421 gacatagctt ttgtcacgac ctctcggctt atcctacgag tattattcga tacatttata
    15481 tcaataatcc tttttttatt ttatctgcag cttcttggaa cgctccatcg tttgacacga
    15541 ctaaaagtga ggggatagct ttcaaacgtt tcaactgtgc taaatcttct acataaaccg
    15601 ccagtctggc tgaaatctgt tcagatgaat ctccacgttt tttcaggcgc gattgcaatg
    15661 tttctttaga gatcgtaata aagataggac ggactaccgt cccgaaatac tcatataaat
    15721 gccaaaaacc atttgctgtc aaaacggcgt aacaatttcc tactgtcagt ttctttttaa
    15781 tttctgcttt actggaacca tatttatgtt gagcatattg gtcccactct gcaaactcat
    15841 ttcccttgat catctgattg aatgtattgt cagaaacaaa ataataatcc tcttgatctt
    15901 tttccccagg tcttggtgat cgattcgtgt aagtaatgat cttttgttcc ggctgaaaaa
    15961 tagcttctgc gagtgaagtt tttccagaac cagaaggacc gataaataca tagcaataat
    16021 tcattgtcat ttctcctttg atgattgaac aagtgaaaaa gctttggaaa atatttccaa
    16081 agcttttaaa agtaactttg cttttttgta tattatacca gcaagccagt cacaatagca
    16141 cttaaaaagc tgactaaagt cgctgttagc aaaattttca atccgtgttt tgcgacaaga
    16201 tttccttttt cttcatttaa tcccttcatc gcaccagaaa tgatcccgat agaagagaag
    16261 ttggcaaatg aaacgaggaa gacagatata attgctgttg tacgctcagt aaaatggaaa
    16321 ttaccatttg ctaattctgt catagcaaca aattcatttg taaccagttt agtcgccatg
    16381 atactaccgg catccactgc ttctttccat gggattccgc tgatgaaggc aagaggggca
    16441 aagatgtaac ctaggatctc ttggaaagtg atgccgaata tcccgtggaa gatagcattg
    16501 atcatggcaa tcaaagcaac aaaaccgata agcatagcag caaccgtgat cgccacatgg
    16561 aaaccatcaa gaatgtattc tcccaacatt tggaaaaatg tctgttcttt gttttcttca
    16621 atgatcagct catcttcttt ttcttctaat acatagggat ttacaattga agccagaata
    16681 taaccgccaa ataagttcaa aacaagggca gtgatcacat atttagaatc gatcagtgcc
    16741 atataagatc cgacgatcga catagaaact gtagacatag ccgatacact catggtgaac
    16801 aaacgtttct cagataggaa gggtaattcc ttttttatgg aaataaaaac ttccgattgt
    16861 cctaaaatag cagaagctac tccattataa gattccaatt tgcccatccc gttgatttta
    16921 cttaatccta gaccaacagc tttcataaat aatggaagaa tcttgatata gcgtagaata
    16981 ccgataatag cagaaataaa tacaattggc atcaatacgg aaagaaagaa aggtgcactt
    17041 cctttatttg ctacaccggc aaaaacaaag tcaacacctt gcccagcaaa agcaagaaga
    17101 tgatcaaaca tttttgccaa tacagaaaca accgctgtac caaaagttgt acgtaataat
    17161 acgaaaccaa gaacaagctg taaaacgaac atcacaatta gtggtttcaa tttgattgct
    17221 tttttgttac tgctgatcaa aaaagcaagc cctaatgtga caaataaacc aataatacct
    17281 aataaataac tcaaataatc actcctattc caaattccgt tttattttac ctgttttgca
    17341 aataaaatac taatctttag tgaaattttc attacttttt tagagtgaaa cgcattcatt
    17401 ttccattaga aaataaagcg aacaaaataa aaggtttaaa aagtgtaacg tcttagtaaa
    17461 gtctataaaa aaacgaaact atcgattaag ctaatagttt cgttttcaac atttataagt
    17521 aaactttttc tattggtaat atagattttc ggaagggtag acaggtgcgc aggtaatatc
    17581 gattcctagt tttttcaatg tttgttcatc atttttattg accatcacag tagagtgggc
    17641 ttgtgctccc tcaagttcag ctagtttatc ataagcaact tgagcgattg gattcgttac
    17701 tgcactgatt gataaagcga tcaagacttc attgatgctt agtgcatcca aagaggaatg
    17761 aagtgtcttt gatttcaatc cttgtattgt ttcaagaact aatggtgaca ataaaggaat
    17821 gtcatctgcg atatgggcta aatgttttac tgcatttaag ataactgccg ctgacgcatc
    17881 catcaatgaa cttgtacgcc cggtaatgat gacttcatct ggtaattcga ttgcaatcac
    17941 agcagaagga tcttttgtag gactttgcgc ttgaatctta tctgcatagt catgggcagg
    18001 gactaccacg tttcggtctt caggacgtaa accgacttct tccataatca gtttgattcg
    18061 attaactgct tcttcgtcga tcaatccttt tttgaagtcg cattctgttt ggaaataacg
    18121 acggatgatt tcttgtttag aggcttcttg gacaacggta tcatccacga tcccaaatcc
    18181 tacacgattc acacccatgt cagtaggaga ttgataaaca gattctttac cagtaatttt
    18241 ttcaataata cgtttgatta caggaaatgt ctcaacatcc cgattatagt tcacagctac
    18301 tttattgtag gcatcaaagt ggaaggaatc gatcatattg acatctttta gatcgactgt
    18361 ggctgcttca taagcaatgt tcagcggatg tttcaacgga acattccata ctgggaaagt
    18421 ttcgaacttg gagtaaccag ctgcatgtcc tttttggctt tcatgataca gttggttcaa
    18481 ggaagtagcg agctttccac ttcctgggcc aggagctgtc actacaacga ttggtttagt
    18541 tgtttcaata tactcatttt ttccaaaacc atcttctgag acgatttttt ctacgttgac
    18601 tggatagtct tcgatttctg agtgtttata gaccttgatg tttcgtcttt ctagtttatt
    18661 gataaagact ttcgtggcag gctgtccact atagcgagtg ataacgacac tgttgattaa
    18721 taagccataa ccacgtaatt catcgattaa ccgcaagata tccatatcat aagtaatccc
    18781 ataatcacca cggatcttat tacgttcaat atctccagca tagacgcaaa tcagtatttc
    18841 agcttgatct ttcaattttt gcagcaattt gattttcgca tcttcttcaa atcctggaag
    18901 tacacgtttc gcatgcttgt cgtcaactag cttcccacca aattctaaat ataatttgtc
    18961 atagtggttc actcgttcca aaatatacgc tgactgctct tcaatatatt tttctgaatc
    19021 aaaaccaatt tttttcacta ggttccctcc ttaagtacta aagcattttt tcattttttt
    19081 gaggattcgt caactggaag agcgaaattc ctcaaaaaaa caaagaaaat ggtttaaacc
    19141 aacttgtcta gatagttatt cattggtatg atagtttttg ataaggaagg tgctacatga
    19201 aaaaaagaca gaaaaagaaa aacgcatata aacactatat ccgttcgatt tttaccggtt
    19261 atgaaagaat gcttgaagat cccgaattgg aacaattgac gtttacttat ctaaacgaag
    19321 aaacgcagct aactcgtgat gagcatcagc gcattcattt cacaacaaga gatctgccta
    19381 gtaaataaaa aataagataa aggtcatcgg attcgattct gtcctatcag atggaaagac
    19441 tagttgatcg aaaaaaaggc tgtaccaaat tttggtgcag cctgttttat ggagcattgc
    19501 ccgctctttt ttataacaat tttttacaga aaatggtact attgaagtat taataagtga
    19561 aaaacagatg agtaagagga ggcaagtagt atgaaagagc cagatacaaa tgcaaattat
    19621 gagccagacg aactagagga gacgaatgcg gatcaggata caggacaaga atcgtcttct
    19681 ttttacgata tcaaagaaaa agcaagcatg aatctttccc aattattaga agacttacag
    19741 gcttttgaaa aagctgtccg cgaagaagat atccctgaga tctaccgttt atacaatggc
    19801 cgattgaatg aagaattaaa aagaagctca aatgaaaatc acgagatcga tcaattgctg
    19861 atgcgtaaga tccatgatcg ttttttacag gaatttcctt ttatggaaca agtagaaaac
    19921 atctcgccaa cgatgagcta ttacaaaatc ggcacttatt accatgatcg gcccacggtc
    19981 ggtattgatg caagtctgcc agaaattttt gttttgccta agatcgatga agagtgggag
    20041 aaatattccc aaccggagtc aacggactat gacaaaaaaa tcaatgagct agacgcaaag
    20101 gtgatcactg ctcagacaga aattgaacgt ttagatgaac aaataaaaga aatcaatcga
    20161 caaatgactg atttgaacga caataaagga ttcttgaatc gtaaaaaaat cgaggaagaa
    20221 attcaagaat tagagaagaa gaagcaagta ctatctaatg aaaaattagg ctggcttcct
    20281 tatattgaga cgcctgaaac aatccagcag caaaaagaag cattgaagca agaagcaaga
    20341 gcagaccagc ttcgtgcagc catcgtagaa aaagaacaaa ggcaaatcag acgctatttc
    20401 ggtagcaaag agggattcgg tcaagcaatc catgaattct tgatgaatta tcttggcaat
    20461 gagaatccta ataatcaatc taatgaagga ggttccgagt atgaatgaac acgatgaagc
    20521 agaatggaca aaaaatgaag aacaaacaga agatcatgaa gaaacgaaca cttcattgga
    20581 agaacaaaca agtaatcctc tggatgacac agaagaaatc cctatgctag aggaaacaaa
    20641 aatacacgaa aaagaaaaag taactccgac gaatacgaat actgcagaaa acacccatgc
    20701 ttacgaaata actgaaaatc ccgggtattt agaaggaaaa gagcaagatc atcaagatat
    20761 cgtcagtttg attgaaacag cggaagcaga attagcggat ttacgtatga gaaaagattt
    20821 gatcgaatca gattttccac aattattaga atcatatgat cgttttatat tgaatgaaga
    20881 accaatctcc acgatcggaa agacaagcct gatcgaatac ttcacgtatg aattactgaa
    20941 accgttgaat gatattggtc tggaacggtc aaattcagct tatgacacat ggaaaacaag
    21001 acatttttcg atcaattata cgttgaatgg acaaaacgaa ttagtctttt cctttgtatt
    21061 accgaccatc gatcaacgat accaagtgga atcgatgagt ctcctaaacg tatcaccaga
    21121 gacaatggaa atcaatgtcc aagatgaccg ggtgctttct ttgatccgac actggtcagt
    21181 ggatcgagta ttctctgcag ggcagatcac gatattcaat cacaaattga atcaattatt
    21241 agcccatgca agaacacttg gttttaccgt taatcagaca ttactagaca atacgaagcc
    21301 acttcgtttg aatcttcaga gcgaatttga attgacgaat gaagtattgg atgatatttt
    21361 tatcgtggca atgaaaaatc catcctacga tatggaaaag atcaacgaaa ctacttatca
    21421 agtacgatta gataaaggac agtctttaac gataacaaca aacgaaaaag atcaaacagt
    21481 cttgtcgatc tcatctggag actacccacg atctgtcatt gatttcttta tcaattacga
    21541 attcttggtc ccattaatgg tgagaaagtc ctgattggat aagttggatt accagatgtc
    21601 attcagataa ttctgttcca aaggacttgc ggcagttatc cagaataatt gtcacaagtc
    21661 ttttctgtat gtactaaatg gacgtgaata acttgctgat gaaggaggga tttcattagg
    21721 aatgtccaca aataaaatag cacagcttag cttattgtct gctgcttgtg tagcaggtag
    21781 gatcgctttt caatttattc cgaatttcca gccaatgact gctatttttt tatttatagt
    21841 actttactta agcttaaaag atgcgttaat tgtcatgagt ctttctattg cgatcagcag
    21901 tttttatttt ggtgttggac catgggtcat cggccaatgg atcagctata ctgttgttct
    21961 gagtttgttt tcaatcgtct gcttgagaaa aacagtgcaa aggaatctat ggttaaaggg
    22021 agtctgtttt tttctggcgg gcatggttta cggaataggt atgaccgttt ttgatacgct
    22081 gttatatcgt ttgcctcaac cttggatcta ttaccttcaa ggggtgtcgt ttgatttgat
    22141 gcacagtata ggcaatgttg tgttctttct tgtttttctg ccagtcgtca aacgttttta
    22201 caatcattca ggaggaaaaa atgaaaaaaa taatttatag tttgcttgca atgagtgtca
    22261 gtatactcat tttgacaagt tgcagtacaa cctatacaca atcggcttcc aaccaaaagg
    22321 aggaagtaaa aacatcgcaa aaagcaacaa tcacgttaca agaaaatggt caaaactttt
    22381 cggaaaaaga agtgttcttc aaaaaaggcg atgatttact gagtattttg aaacgaaatt
    22441 ttgaagtcaa agaagataac ggcttcatca cttcgcttga agggcactca caggatgaga
    22501 aaaatcaact ctattggatg tttactgtgg acgggaaaag tgctactact ggtgccaaag
    22561 agatcaaatt gaatgatgga caatcggtca ttttcaattt gtctaaacta taagtttcat
    22621 aaaaaactgt taaagggcga atattgccat aattcagtga gttcagttga tgaaagaagg
    22681 aaaataacat ggaaaatttt aaaaaaagcg gaatgttttc cgtaattgct gctctagggg
    22741 ctaatattct agttgctatc agcaaatttg tcggctatgc aatcagtggc agtgccgcca
    22801 tgctaaacga aagcatccac agtatcgttg attgcagcaa tcagattttg ctgttattcg
    22861 gtgataaaca agccaataaa ggacagagcg agttgcatca atttggtgaa ggacgagcaa
    22921 aatacttttt cagtacaatc gtcgcaatga tgcttttctt cggcggtggg gcacttgggg
    22981 tgatggaagc ttttgaaaag ttgacgcatc catcccatga agtgggtaat ccgatcattg
    23041 ttatagcaat actgttattt ggtttggtaa tcgaaggaag ttcgttacgc gtggcaatga
    23101 aagaaatcaa agaattgaat actgaaaaac tttccacgat gcgctttttg cgcgaaagtc
    23161 gacacagtga aatactgatt atttttacgg aagacttgtg tgctgtaatc ggtttggtct
    23221 tggctttagc aggaacaata ttgacttatg caaccgggat tgctgcattt gatgcgatca
    23281 gcggattgct gatcggtttc ttgctgatgg gagccgccat tttcctagca aaagaatttt
    23341 atagtctgat catcggtgaa agcgtgacag caagcgattt atcaaaaatc aagttagctt
    23401 ttgaacgtcc tgagatcagt cggctgatcg atataaaaac agttcattta agtccaacgg
    23461 agattttagt tgcagcaaaa gcagatatcg ttggtaacaa agagaatgaa gcttactcgg
    23521 tcatcaatga tattgaaaaa aatatgcgtc agtctcttcc tgacaagaag atgtatatat
    23581 acattgaaac agataaatat gacccaaatt attctcgtaa ataaaacgtt tattcatgaa
    23641 ttgaagcaaa aatgagaaaa atataatctt gtttttaaat aaaacggcta caatttagcg
    23701 aatttatgtt acaatgagtc cgctgtttat ttgttgtaat taaaggagat attttaatga
    23761 acaaaaagaa aagtgcgcca tggcttcaag ctttgcatgc agtgatgcca ctttgtataa
    23821 gctatatacc agtaggatta gcttgcggag tattgttgca aaaagttgga tttgatcctc
    23881 tcttatcagg actgttatcg attctggtct tttccggtgg cgcgcagttt ttagttgcat
    23941 ctatgcttac gacgcaagca tcatttgcaa cgacattatt gatggttttc tttttagaat
    24001 tacgctatac attattagga gcaagtcttg ccggttttat gaaaaaagaa aagcggacgt
    24061 ttttggctgt cttttctcaa tcactgaatg atgaaaacta tgcggtgaac tacttaaagt
    24121 tttcaactga cccttcctgg aataaaagaa aggctttata tgtcaattgg ttctcaatga
    24181 ctgcatgggc cggtagcaat atgatcggta attttttcgg ctcggtgatt cgagtagatg
    24241 ctgaccttgt ccattttgct ttgacggcca tgttcatttt catgtttatc atgcagatga
    24301 aaagcgcact actgatcttt acaggtttat tctcaggcgt attaggggtc gtattcatgg
    24361 tattattcca aaatactttc ggattgattg cagcaacagt cattgcttca tttgccggat
    24421 ttatgctgga gaaggcattc aaaaaagaaa aagctaagaa actaagagac cgcggtaaag
    24481 atgtcaatga gccgctcttc aacttcccgg aacaggaggc caatcaccat gactaaacta
    24541 tatttgctac ttttagttgc ttgtctgttc atcgtggcat atatcccgcg cttgttcccg
    24601 atgctttatt ttactcatcg aaaagtgcca tcctggttca gtgactggat gaaatatgta
    24661 ccggtggcat tatttgcggc gttagctttt aaagatgttt tcattactca tgaacatctg
    24721 gatattgctt ggaatatcaa aatagctgca atgattctag tagcaggcgt ggcttacaaa
    24781 acacgttcga tggcgttgtc agttttgaca ggacttgcgt ctgtcttttt gctgtctatg
    24841 ctttaaactg ttttatttta ttaaaaacag agattgcgac ataagttgtt caaactgatc
    24901 tatccgaact gcatttgcaa cagtcaattc tggatgcaag tttattcgta gggataaaaa
    24961 agattagtgt tggcttatga tgcaagctct tttttatttt aggaattaga gagggatttg
    25021 tccttctatg attttttgct ataataggga agatgtttat tttatgaaag aatagttgag
    25081 ggaatttaaa tgaataaaaa attgatgcaa ggaacatttt ggctaacctt tgctaatctt
    25141 ctatgtaaag ttttaggggt agtctatttg attccctggc taagtatgat ggggaacaat
    25201 caagatggta tgcttgctac gacattgtat aatgttggct atcttcctta tggattgttc
    25261 ctgatgcttg gtacagtcgg atttccaaat gcgattgcaa aaaaagtagc tgtagccaca
    25321 aaagaaggag ataacgctgc ttgtcggctg atttttagaa gtacgatcaa tatcatgttt
    25381 gtcatcggta tcgcctctgc tgcactgatg tatttatttg ctcctttact agccggaatc
    25441 agtccgattg ctaacgttaa taatgggata ctagctatca gaagtttatg cccatctttg
    25501 attgctatcc caattcttag tgcaatgaga ggatatttcc aaggaaaaaa tgatctgcgg
    25561 ccttatggaa cttctttgat tatcgaacag gctgtgcgag tgatcgttat cttggctggt
    25621 acttattact tgcgcgtatt gactgacgga accatattag aagctgtatt gatcagtaca
    25681 gtcgcttctt tcttcggtgg gttagctgcg attatccata tgtatatcgt cggacgcaga
    25741 aaagacttct tcgaacttaa agattttttg atttccagcc gttatttcga aagagaaaac
    25801 cgatctgcct ctgtctctat cattcgggaa acactaccgt ttatttttgt cggctcagtc
    25861 attactatcg ttcaaatgat cgaccaagta acgatgaaac cactgcttca ctttttccgt
    25921 ccagagatcg cagatcagca actggaattc ttattcagcc gtgcttctgt caatccaaat
    25981 aaattgacat tgatcctgat ctccatggta ggaacagtag ctataagcag cttgccaata
    26041 ttaagcacga tgaagaaaaa agatcggata caaatcgaaa aaacagtagg agatagtttt
    26101 tcgattgcgt tattgattct tcttccttca ttgactggaa tgtctttatt agctggacca
    26161 ctatacacat tgttttttgg ctatgatcct gaaagtgtcg gatatttcca aatggctttg
    26221 ctagcttctt tgtttttctc tttattcacg atcctatcta cgatgcttca atctttgaat
    26281 caccatcgtt ttgcgatccg attaactgta gaagcaatta tcctgaaagt catcttccaa
    26341 gtaatcggat taggattagt tggcggatac gggatgagct tatcaaatgg cttagcattc
    26401 ggtattgtct ttgttcgcgg ctatcacttt atgtgcaaag aataccgaat agcaccttta
    26461 gcaaagatca gcaatttttt cttaaaaact ttccgctcca ccctgattat gcttgcagta
    26521 tgttttgccg ttttcttttt gctgaatcag cgattgtcaa tggaatcaaa aagctatgca
    26581 atgatttatt gtgtggctgt aggaagtatt ggcggcttag tatttttatt ttctcaattc
    26641 ggaaaaaatg ggtttcgaat gttgaaaaat gttaaacatc atagcagaag caaagaatag
    26701 gttaactaat cgttttttgc tgtcacttga aaaacggcaa ctcgtatgat tacgcttgtc
    26761 gtttttctat tttccaattt tagtttcata tctaatctta cttatgatat agttataagg
    26821 tctggaaaaa ttctttgaaa cgaggaaatt aaacacatga aacttgcagt agttacagat
    26881 agttcggcat atctgccgga acgtatcaag aaccatcccg acttattcgt tattccaatc
    26941 cctttgatta tggatgggaa aatttataac gaaggaatcg atatcgaagc ggatgaatat
    27001 tatggacttt taaaaaacag taaagatttt cctactactt cacaacctgt cgtaggggaa
    27061 gttttgggtt tatatgagga attgaaagag aaagggtatg acacgatttt aagtatccat
    27121 ctttcttcag ggatttctgg ctttgtcaac acattatttg cgatgaaaga tgacatcagc
    27181 ggagtaacgg tcattcctta tgactctaag atcactagta tgccgatggg acacatggta
    27241 gaagctgcct tagacttaaa tgatgaaggt cagtcccttg atgaaatact tgcacatatc
    27301 gatcgaatcc gagataatac ctacgcttat ctgattgtag atgatttgaa caatttagta
    27361 cgaggaggac gtttgacaaa tggtgcagcg ctgattggca gcttattaaa aatcaaaccg
    27421 atcctgacat tttctgaagg gaaaattgtt ttattcgaaa aaatccgttc aagtaaaaaa
    27481 gcatttgctc gagctgaaga aattattggt agaagaaata acgaaataca accgccagtc
    27541 aaactttacg tgatacatgc aaataattta gaagtagcga ttgcggagaa agagaaattg
    27601 cagaaaaaat atccaaatgc agaaatcgaa attggtcatt tcggaccagt cattggtaca
    27661 catttaggtg aaaaagccat cggcattgcc atttcagcgc aataattcct tttattcaaa
    27721 aaacatacca aaaatattcc aacatcatct tggactttct acatgttact aatgagcgtg
    27781 taaaagaacg agatggtgtt tttatttcta tcaatgaagc tctttttctt tgcaatcctc
    27841 acttcaatcc tctataatgt cgcatatagt ttagtaaatg agtaaactac taatttactt
    27901 atttactaaa aataaaagga tgaggagtta aaataatgga aataccaaca aatttaaaac
    27961 ataaaccagt aatcgttgta gaagactatg ataaagttga tggaagaaat gcattaaata
    28021 cggatgcaaa agggctttca ctgggccttg ctcagtggaa tgatcgtgga aaagtcgata
    28081 tctcaggcaa ggtatggcga catactggag aaaaatggtc acgacagtcg gaagaattac
    28141 caatcacacg tattttagat ttagcgatct tagctgcaca aggaagttta tacttccaag
    28201 atgcttatcg ttatgaaaaa ttttatgatc cagaaaatcc agtcgtagac atcattggat
    28261 tacaagggaa ccgaatgacg gtagaagtag ataccaaaaa tccaaagatc gatgaagaca
    28321 tcattttgta ttacgataca ctacaaaaag acggagaact gattggggaa cgattccgta
    28381 ttttaaaacg tcttttagat gagctaggat attaatagac agagatgatc aaaaggggaa
    28441 gagaagcatg gagaatttct cactaacaga aaaccgaacc ttttcacggc tagaaaagca
    28501 aatgatctgg aagaaaccga aaagccatcg gacaagtgca gaagaatggc ggatcgcctc
    28561 cgaaatcaaa gggaattggc aagatcctga aatgaaaatc agtaacgtac ttttggaagg
    28621 agatgccggg tcggggaaga cacaattagc caaagcacta tctgctgatc tgcaacttcc
    28681 ctatacaaaa gtgacctgtt ttgcagatat ggacaaatca gatgttttcg gagccttatt
    28741 acctgtagta gattctaata aggaacaaga ccaagaatta ctagaagcta tttaccaaac
    28801 agatacactt gaagctgtac tgacactgat ccagaaccat tacggcattg atcctttttc
    28861 tgctaaagaa aaattagcag agctagttca aaggatcgaa gctgattatc cagatgcaat
    28921 ccattacagc tattaccctt ctgaaatcgt tcgagcgatt gaaaaaggat atttattaga
    28981 gattcaagag ccgactgtca tccgagatgc ctctgttctt gtggcactta actcagcgct
    29041 cgaaccaaat gggatgttga atttaccgac aggaatcatt cgtcgccatc cagattgcgt
    29101 cattgtgatc actacaaatc gaaattacca aggaaatcgc ccattaaatg aatctttaag
    29161 agatcggatg caacatgcgg aaaaaatgga tcttcctgcc ttagaagtca tggcagaacg
    29221 tgcgatggcg aaaactatga tccaaaaaca agaacttctc ttaaagatgg cagagattat
    29281 ccgtttgttg gatgaaactg caaaagctaa cgccatcaaa ggtgtagcag gaatgcgttc
    29341 ttatttttat tgggcaaata cctataagca aggacaagat ttactccagt cgatttatcc
    29401 aaaagttttg tataaattat ccactgattc agatgaattg gcaattcttg aacaagcttt
    29461 gtctgacagt ggattgctac tggaacttca ggacatattg agaaaagaaa aatggggtca
    29521 tcctcaatct gagcatacaa aaggaagaac cattagcgcc gaagaagcaa atgaacgaaa
    29581 catcactgaa aatgctgaag aaattctgcg cttagatgaa aagaaatcgt tgtctgctga
    29641 agaaccaaat gagggagaag agaaacaaga agaaacaata gaaaaaaacg agattcctcc
    29701 tcaaatgcaa aaagaacgca gtagcgatat cgaaggaaaa aatcaaaaag aacaacaaac
    29761 aggagatgat tctcaagaaa tgtctgcttc tgacatggaa gcacatgata aggaaatcaa
    29821 gaagcaactg aataaagaag cgcgacaaat catgaaggaa acgattcatg aaaaagaagg
    29881 tctcatcgtt caccgaccag ctttccaagg aaaaacgccg gaagcacgtg agctacacat
    29941 gcaagtaatg ccaatagtag aatcacttag ccggcaaatt ttagagttac tggataatga
    30001 acaaacagag acgtaccaaa aaggaaaata cgaaggtcag cggttcaatg caagcaaagt
    30061 agcatatggt gatttgagaa attttgacaa aaagaacccg ccacatgagc aaccttcttt
    30121 agcggtagct gtacggatcg atgaatctgg gtcaatgata cgggatgatc ggatcgaagc
    30181 ggcaaaaaaa gcagcgattg ccattgccga attttctaag aaagtcgata tcccattgtt
    30241 gatttacgga gatacagcag accgttcgtc aagagaaaag acttctttgt tttcttataa
    30301 agaatttgaa gacggatttc aatggttaaa tgaaaaatta gtcactatga aaccaaggca
    30361 aaacaatcgt gatggtgctg cacttcgttt agcagcagaa aaattaaaca gacaatccgc
    30421 aacaaccaaa ctgttgctta atattagtga cggtcagcca aaagcgttgc cggattatac
    30481 aggcaaaaaa gcaaaagaag atatccagtc tgttttgaaa gaatatgaac gtcaaggaat
    30541 cctatttgtc tccgcagcta ttggccaaga caaagaagaa atcaagtcga tctacggtga
    30601 aagtcgtttt gtagatatta ctgacttgaa tgaatttccc aagcaaatga ttcaactgat
    30661 tgcccgctat ctatgataaa ataaagctca acgaacgcac ttagcagatt cgttgagctt
    30721 ttcgtttcta gttaccggta acaaggatac ttctaaaata gaatcggtta taatcaagag
    30781 ggaccgttaa aggagtgaaa cgatatgata caagaacaaa aatggtggaa agaagcagta
    30841 ggctatcaaa tctatcctgc tagtttcaaa gatagcaatg gcgatggtca aggagacatc
    30901 aatgggatcc gtgaaaaact taattatttg aaagatcttg gtatcggctt tatctggatc
    30961 aatccgatct atcaatctcc atttgtcgat aatggttatg acgtaagtga ctatcaagat
    31021 atagaagaga gattcggaac gatggaagat tttgatttat tgctaaaaga agcacatgaa
    31081 ttagggatca aagtgattat ggatcttgtc atcaaccata gttcggatca gcatcaatgg
    31141 tttgaagaat cgaaaaaatc taaagaaagc ccgtatcgcg attattacat ttgggtcgac
    31201 ggggtagatg gcaaagaacc gaataattgg acatcgattt tcggcggttc tgcttgggag
    31261 tattctcatg aaactggaca gtattatctg catgtttttg caaaagaaca accagactta
    31321 aattgggaaa gcgagaaatt gaaagaagaa ctattcaata tgatccgatg gtggttggat
    31381 aaagggatag atggatttcg tttagatgcg atttctcatg taaaaaaaga tgaatattca
    31441 gtaaaagcca cagagaaccc tttctcaccc tttcaaaatg tctcaggaat cgaagaacat
    31501 ttgaccgatt tgaaacatgt ttttgaagag tacgatatca tgactgtcgg agaagcaagt
    31561 ggtgtcactg cagaagaagg accacaatgg gtagggaaag acggttattt cgatatgata
    31621 ttcgaatttg atcatatcca tatctggcag caagaaaaag aagggcaatt agatgtcctt
    31681 aaattgaaac ttgcattaag cgcttggcaa acttcattgg atggtatcgg atggaacgct
    31741 ttatatatgg aaaaccatga tgttcctcgt gccgtttcag tgtttggaga tactcgtccc
    31801 gatttttggg ctatgtctgc aaaagcaatc gctatgatgt atttcttttt gcaaggtacg
    31861 ccatttattt atcaaggaca ggaaatcgga atgacgaata tgccctttga atcgatcgat
    31921 caagttgatg cagtagattc gaaaagactt tataaaaggc tgcttgcgga aggtaagaca
    31981 agagaagaag cattggatat cattcgtgaa acaacgagag acaacagcag gacacccatg
    32041 caatggactt cggaacaata tgctggtttt tctacacatg aaccttggct gatcactaat
    32101 ccaaatacca aaacgatcaa tgtagaacaa caagaatatg aaccagagtc ggtcctgcaa
    32161 ttctataaga acatgatccg cattagacaa accaataaag gtctgatata cggttcttat
    32221 aaagaatatc ttcatgaaca tccacaactt tatgtctatg aaagatattt agaagatgaa
    32281 caatatctta ttatggtaaa cttaacagaa tcacttgctg actatgaact tccaaaagaa
    32341 gcagatcagt cctggacatt actcttgtca aattcctcta gcggagaatt tgaagctaaa
    32401 ggcatactag caccttatga agctcggtta tataaaacaa acaagtaaaa cttcctcgtt
    32461 aaagttcatt agttggactt tgcgaggaag tttttcagat tgctctgtca attactcatt
    32521 tcaataattc gctctaggac caccgatata tttaggacga gagcgaaggg ctgtcacgtg
    32581 agcttgtcca agggttttca aacgaggtct gacaggtact tggacatgtt tgatatgcat
    32641 accgattgat gtgtcaccga tatcgatacc ggcttgtcca actacgtgtt ccacttcgac
    32701 aggatcattg aactggtcaa aagcagcaac agaacaagca cctccagcat gtagtgcagg
    32761 aacaacagag acaatttcga aattttttgc ttctgccact gttcgttcta ctactaatgc
    32821 tcggttcaaa tgttcacaac cttggacagc tagcgcaatt tctttaggat ccaacaactc
    32881 ttttaacgta cggatgatcc attgaccaac ttccgcactg gaattttttc caatatgtcc
    32941 tccaacgact tcgcttgtgc tgcatcctaa aacaaaaaga tcaccttttt tcaagtgtgc
    33001 ctcagccaat atgtcattaa ctatttcagt caattggtct tttaattctt tttctgacaa
    33061 cttcattttc taaaaccttc tttttcaatt aatattgctt ccgtgcttga atacgttgaa
    33121 gacttgcagt tataggaaag gcaagtccca ttccaatcag attttggaag atgtttcctg
    33181 gtatagaagc cactccagcc ggccaatcat ataaaatcca accggcgata ccatagccga
    33241 tgatcataac taagcttcct aataaaagcc ctaatcccca catacgagta gaagatttgc
    33301 tgaaagaacc agcaacatat ccttgtaacc cgtggatcac taatgaaaaa actgcccact
    33361 gcggatatcc tgaaatcaaa tcgatcaata gaccactgga agcaccaaca actaatccac
    33421 ccgttggacc ataaagaaaa gcagcggtat agatcccggc ctcgcataat gtcacaaatc
    33481 cattcgtagc cggtacaggg atcaaaattg ttaatgaaag ggcaactgtc aacgcaatca
    33541 gcatagcata gatcgttaat tgcttagttt tcatttctca ttcctccttt ttgaataccg
    33601 ccagaccaga cacttccggt atgatcgttc atcagcacgc cattagaaat acaatgggca
    33661 acaaattttt tactttctgc tactgctttg gtaaaatctg cccctaacac aagattcgct
    33721 gttattgcag aagaaaaggc acaaccggcc ccgtttactg ttgtagtgtc gattttttta
    33781 tgagaaaata cctcataatg atcaattgaa tagagaagat ccacagcttc atctccagcc
    33841 atccttgtgc cgcctttgat cacaatgttt tttgttcctg aagcagtgag ttctttagcg
    33901 agatggatca tttctgttaa cgaagaggga agagcttgac cagaaagtaa agcagcttct
    33961 gccaaattag gcgtaatcat cgtaacaagt ggaaaaagtt cttcgatgag ctgcgaaata
    34021 tacaattgat tgatcacagc ttcagtttct ttgaatgcca aaacagggtc taaaatgatt
    34081 gggatatttt gttttgtttt tatgaagtct cgaacaacca tgattgcttc acttgaattc
    34141 aataacccaa ttttgatacc atctaatgaa gtcattttat caatcgaaac taactgtcgt
    34201 ttaagcaatt ccaaagatat agattccagc ataaatcgct cattaatatc tagtgcccct
    34261 atagaagtca aggcgcttag tccgaataga ccaaaattct caaaagtttt taaatctgtt
    34321 tggattcctc caccagcaaa tggatcagaa ccgccaattg tcaagattct tttcataaca
    34381 ttttcctcca tgaataagag tataacgaaa ttttcaaaaa agaaaaacag ccaattggca
    34441 tatttttatc tcatccaatt taaaaaaaca aaaagaaaag aaagaccaaa atggatcttt
    34501 ctttccttaa atagttagga cttttgtgat tttaattctt tctcgatttg aagccgttgc
    34561 actttcattg tagctgttcg cgggattgca tcaaaatcac ggatgatagg gacgttcaag
    34621 cgaggaagtt catggacttg ctcccaccat cgattccaat ccatttcttt atcaggagct
    34681 aaagcaataa tcggttgtgg agaatgattt ttatccctta caatcactac ttctgccaaa
    34741 aaatctaacg aatctaataa aaagtcttca atagctaatg tactattgat cgtttcgatc
    34801 aaatccactt gccgatcttt caaaaatagg tggccatgct tatccataaa accgtaatct
    34861 ccgctatccc accaatcgcc ataaacattt tcctggaacc gtgcatcttc cttgtaataa
    34921 gtcaaagccc gtcctttaga cagtaattgt atatgaccat ctgtgttttc aggtaggaca
    34981 ttcccaactg aatctgtaat ccgagcgctt gtcatgtctt ccagtccaac gcccatatct
    35041 cttgcatcac ttgttttcaa actctctagt gtatgagcct taagaatcat tggtccgcat
    35101 tcactttggc catatacttg aagaaatacc gcatcctgtg ccatcgacgt tcgcaaaaat
    35161 gtcttcattg tctggttgtt tatagcatca aaagtggagt gatagtatcg gatacccgaa
    35221 aaagcttctg gatgctcctt agcagtaaaa cgccactgaa caaagttatt cggatgggtc
    35281 tctagtgcaa ttggccggtg agcttccaac atatgaacaa cttttgaact ttgtgcgttt
    35341 gctaaaggca tcataggaaa tcccatggac atcaaagaag agataccaat attgaatctg
    35401 gaatgcactg gagagatgtg aaaagcgatt aatttctttt ccgaaatttt tgtgaaaact
    35461 gttttttgcc atttcgtccg ccatcccata gaatgagcag aatgacaaat aagtttaggg
    35521 ataccagttg taccagaagt atgggtcata taagaaattt catttttgtc taaaaatgat
    35581 tgagaaacag acaaagcagg ttgttccatt aaataaagaa taggaatacc cgtggtgcta
    35641 gttaatttta atatcctaaa gaatatctca aagttcc
//
LOCUS       DAFLWC010000018        34827 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.018, whole genome shotgun sequence.
ACCESSION   DAFLWC010000018 DAFLWC010000000
VERSION     DAFLWC010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34827
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.018"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(478..2370)
                     /locus_tag="L1V17_000861"
     CDS             complement(478..2370)
                     /locus_tag="L1V17_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1235645.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(2367..4094)
                     /locus_tag="L1V17_000862"
     CDS             complement(2367..4094)
                     /locus_tag="L1V17_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1235646.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(4110..4760)
                     /locus_tag="L1V17_000863"
     CDS             complement(4110..4760)
                     /locus_tag="L1V17_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBN1235647.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4964..5260
                     /locus_tag="L1V17_000864"
     CDS             4964..5260
                     /locus_tag="L1V17_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBN1235648.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5452..6072
                     /locus_tag="L1V17_000865"
     CDS             5452..6072
                     /locus_tag="L1V17_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HBN1235649.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(6164..7330)
                     /locus_tag="L1V17_000866"
     CDS             complement(6164..7330)
                     /locus_tag="L1V17_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBN1235650.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(7342..7695)
                     /locus_tag="L1V17_000867"
     CDS             complement(7342..7695)
                     /locus_tag="L1V17_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBN1235651.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            7823..8845
                     /locus_tag="L1V17_000868"
     CDS             7823..8845
                     /locus_tag="L1V17_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HBN1235652.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            8864..9025
                     /locus_tag="L1V17_000869"
     CDS             8864..9025
                     /locus_tag="L1V17_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235653.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(9284..9718)
                     /locus_tag="L1V17_000870"
     CDS             complement(9284..9718)
                     /locus_tag="L1V17_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235654.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(9828..11687)
                     /locus_tag="L1V17_000871"
     CDS             complement(9828..11687)
                     /locus_tag="L1V17_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBN1235655.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(11805..12965)
                     /locus_tag="L1V17_000872"
     CDS             complement(11805..12965)
                     /locus_tag="L1V17_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HBN1235656.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(13272..14696)
                     /gene="araA"
                     /locus_tag="L1V17_000873"
     CDS             complement(13272..14696)
                     /gene="araA"
                     /locus_tag="L1V17_000873"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HBN1235657.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(14712..15410)
                     /locus_tag="L1V17_000874"
     CDS             complement(14712..15410)
                     /locus_tag="L1V17_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBN1235658.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(15367..17028)
                     /locus_tag="L1V17_000875"
     CDS             complement(15367..17028)
                     /locus_tag="L1V17_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HBN1235659.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            17246..18646
                     /locus_tag="L1V17_000876"
     CDS             17246..18646
                     /locus_tag="L1V17_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HBN1235660.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(18898..19977)
                     /locus_tag="L1V17_000877"
     CDS             complement(18898..19977)
                     /locus_tag="L1V17_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1235661.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(20063..21022)
                     /locus_tag="L1V17_000878"
     CDS             complement(20063..21022)
                     /locus_tag="L1V17_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBN1235662.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSKKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(21034..22545)
                     /locus_tag="L1V17_000879"
     CDS             complement(21034..22545)
                     /locus_tag="L1V17_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBN1235663.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(22567..23130)
                     /locus_tag="L1V17_000880"
     CDS             complement(22567..23130)
                     /locus_tag="L1V17_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBN1235664.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(23136..23999)
                     /locus_tag="L1V17_000881"
     CDS             complement(23136..23999)
                     /locus_tag="L1V17_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1235665.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(24013..24909)
                     /locus_tag="L1V17_000882"
     CDS             complement(24013..24909)
                     /locus_tag="L1V17_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1235666.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(25084..26373)
                     /locus_tag="L1V17_000883"
     CDS             complement(25084..26373)
                     /locus_tag="L1V17_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1235667.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(26345..27862)
                     /locus_tag="L1V17_000884"
     CDS             complement(26345..27862)
                     /locus_tag="L1V17_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBN1235668.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            28060..28950
                     /locus_tag="L1V17_000885"
     CDS             28060..28950
                     /locus_tag="L1V17_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HBN1235669.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(29023..29847)
                     /gene="nadE"
                     /locus_tag="L1V17_000886"
     CDS             complement(29023..29847)
                     /gene="nadE"
                     /locus_tag="L1V17_000886"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HBN1235670.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(29859..31331)
                     /locus_tag="L1V17_000887"
     CDS             complement(29859..31331)
                     /locus_tag="L1V17_000887"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBN1235671.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(31968..32330)
                     /locus_tag="L1V17_000888"
     CDS             complement(31968..32330)
                     /locus_tag="L1V17_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBN1235672.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            32553..33305
                     /locus_tag="L1V17_000889"
     CDS             32553..33305
                     /locus_tag="L1V17_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBN1235673.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(33445..34368)
                     /locus_tag="L1V17_000890"
     CDS             complement(33445..34368)
                     /locus_tag="L1V17_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1235674.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(34383..34655)
                     /locus_tag="L1V17_000891"
     CDS             complement(34383..34655)
                     /locus_tag="L1V17_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235675.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        10280 a         7237 c         6016 g        11294 t
ORIGIN      
        1 tgggcttatt accgcagatg caagcttttg aacaccgttt aaggaagagg ttgtgaaaaa
       61 gtcgcttagt ttcgagtagt aagaaaaatt ttgtgaaaat ggctttctac atttttgcat
      121 aaatttggct taataccgag aaactggctt ttgaacaccg tttaccaaga ggttgtgagc
      181 ctgccgttta actccgagtc acaaggagca atttcaaaaa acagcttctc aggtttgttg
      241 actattgtga cttgtgaccg aggagttggc aggagaacac cgtttaagga agaggttgta
      301 aaatcagcgg tttgacctga gtattagaga tacaaaacgg aaaaatagct tctcatattt
      361 tgccgttttt tgagctaata ccgaaggaca gctgattgaa caccgtttat tcggaaaaag
      421 ggactgtgac acgacttttg tcacagcccc taaaaaaaat aataaatttg tactattcta
      481 tgaagcttct tcttcagaaa actgactgtt ataaagatct gcatagaatc cgtctttttc
      541 catcaatgta tcgtggtttc ctgtttctac gatcgaacca tgattcatca caataatgtt
      601 gtctgcatcg cgtattgtag acaagcggtg agcaacaacg aaacttgtcc ggttttccaa
      661 taggcggttc atcgcttttt gaatcagtat ttctgttcgt gtatctacac tagatgttgc
      721 ttcatcaagg atcaggacat ctggatttgc taagaatgcc cgcgcaattg tgattagctg
      781 acgctgccct tgcgaaatat tgcttgcatc ctcgtttaat acagtgttat atccttctgg
      841 caatttacga acaaaatcgt ctacgtgagc agctttagca gcctcaatga tttgttcgtc
      901 tgttgcatcg tcgttcccat atttgatatt gtcatagata cttcctgtaa acagccaagt
      961 atcttgcagt accattgaaa actgtgcgcg caattcatca cgtgaaagat cacgggtatc
     1021 tacaccatcg taacgaatac tacctccaga aacatcgtag aaccgttcaa gaaggttgat
     1081 cagtgtcgtc ttccctgcac cagtcggacc tacaatagcg accatctcac caggtttgac
     1141 atccaagtta aaatcagtca ttagcaagtt atctggtgtg tagccgaatt gaacattttc
     1201 aaaacgaact ttgtatggtg tatctttttc ttctggaagg ccagattttt cattggacat
     1261 ctcttcttca tccaacactt caaatacccg ttcggctgaa gcaactgttg attggatagt
     1321 gttcatcaaa cttgcaagtt gagtgattgg ttgagagaac tgtgttgtat attgcaagaa
     1381 cgcttgaaca tcccctaatg tcatgttccc atttgcaact tttactccgc ctagtacagc
     1441 gacgaacaca tagcctagat ttttaacgaa attcatcaac ggcatgatga ttgccgaaat
     1501 aaattgagct ttccaaccag cggcatacag attctgattt tctttttcaa atacttcctg
     1561 gtctttttca gtatgattga atgttttaac aatggtatga ccaccatatg tttcttctac
     1621 ttggttattc aataaaccta aacttttttg ctgatctgcg aaaaacactt gtgatttcgg
     1681 cgctacgatc atcacgatga tcaagcttaa agggatcatc aataacgcga ctaacgtcaa
     1741 ttgccagctg attgaaagca tcatcacgat gaccccaatc aatgtgactg cactagttac
     1801 aaattgagtc aaattttgct gcagcgtgct tgcgatgtta tccatatcat tgattgctcg
     1861 agacatgata tccccatttg tatgtgtatc ataataggaa atcggtacac gattcatttt
     1921 ggcttccaaa tcatgacgta attcataaac tgttcgttgg gaaacacgtg tcataataaa
     1981 ttgctgtaaa aagttgaata cagcagaaat caaatacatc acgattactg tcgcaatgat
     2041 ctgcgcgatt ttatcaaagt ctatcggaaa ttttgttact tgttggcctt gttgcatctg
     2101 ttgagcgcca gccattacac ctttgaatat ttctgtggtt gctttcccca agacctttgg
     2161 tgtttggatt tggaagatca cggctgctat tgctagtaca aatacagcga tgatcgcaac
     2221 catacgttta gacatatagc caaacaatcg gcgtaccgtt ccccagaaat ttttaggctt
     2281 ttcacctttt acaccgagat ttctgccagg tccaccatgt cctggaccgc ctgctggtcc
     2341 atgagaggga cgtgtgtttg ttttactcat gctaagtcct cctctcttag ttgtgaatga
     2401 acgatttctt gataagtttc gtttgttgct aatagttctt catgtgttcc tttgccaacc
     2461 agttttcctt catctagcac aaggatcata tctgcatcca ttactgtact tactcgttga
     2521 gcaactaaaa cggtgatact ttctttcata ttcgttttca atgcttggcg aagattggca
     2581 tccgttttga aatccaacgc tgagaaggaa tcatcaaaca catagatatc tgctgttttg
     2641 actaatgccc gtgcaattgc cagacgctgt ctttgtccac cagagaagtt tcctcctcct
     2701 tgttccacat ggctatctaa gccatcttcc atctctgaaa caaaatcttt agcttgtgcg
     2761 atttctaatg ctttccaaat catttcatct gttgcatccg gcttaccata ctgcatattg
     2821 tctcggatcg ttccagagaa cagaactgct ttttgaggaa caaagcccat taattctcgc
     2881 aaattatatt gagtcatgtc actaatgtcc gttccattta tttggatcga accagattcg
     2941 atgtcatata atcgagggat caaattgact aaggtcgttt tacctgaacc agtcccccct
     3001 atgattgcga cgatctcgcc cgacttggct tggaaatcaa tatcttccaa tgcaagtttt
     3061 tctgctccat gatatcgata attgacatga ttgaaggcca atgttgcgtt ttttccagca
     3121 aaagaaactg ttttaggatt ttcagggtca tggataccga ttttttcatc caacacttca
     3181 ttaatacggt cagctgaagc ttgtgcacga ggcaccatga taaaaatagc ggaaagcatc
     3241 ataaagctga tcaagatctg catcgcataa gtcataaatg caatcagatt accgacttcc
     3301 aaagtcatat ctgctatgta gtgtccacca aaccaagtga ttgctacgtt tgtaccgctc
     3361 atgatcaatg tcatcattgg catcatcaat gcgacgatcg tattaacttt gattgccgta
     3421 tttgtataat ctttattcgc taaatcaaaa cgattttctt caaagcgtgt cttatcgaat
     3481 gctcgaatca ctctgacccc tgtcaatcct tctcgaaata ccaggtttaa acggtcagtt
     3541 ttcttttgca tacttttgaa taatggaaca gcaaagtaca tgattccgcc gatcaaaata
     3601 atcattactg ggatgacaac taagaagatt tttgtcaact gatgatcttt ttgataagca
     3661 agtatgctcg cgccaatcaa cgtgattggt gcattgatca tcatacgtaa aaacatttgt
     3721 gtaaccattt ggatttgagt cacatcattg gtcgttcttg tgatcaaaga ggccgttcca
     3781 tatttatcaa acgcatcttt tgtcagactc tctgattttt tatagacatc cgtacgcaat
     3841 tgcttaccca gtttctgtga ttcacgagta gcaaaaaatg tatttgcgat agcagctaag
     3901 atactgatca aagaaaagcc gatcatcaca aaacctgtat gccaaatata atcgacatct
     3961 ccttgcgcta cccctttatc aataatattg gaggtaagtg tcggcaaata taaatctgcc
     4021 agtacttgga tcaccatgaa aactgcagct gcaattgctg aagtcaagga gatccgtttt
     4081 acgattttta gcatctagtt cccttctttc tatttatata ctccgttttt cagccaagaa
     4141 agtttcaaat tgaattcact gattgcttgc tctactgagt aatcttcaga tgttgaaaat
     4201 aagcgatacg aatgcgcaat tgttgtaaat acagtattca tcactaattg gatcagtaat
     4261 tccaattcat gatcattttt tactttcagc ttcgtccgat cgatcaattc aagcaactct
     4321 tttgcatctt gtttgtgttc tttatgtgga tcgtgaggcg ttttttggcg actcgtatga
     4381 ggagcgactt ttcttgaggc acggtaatcc atgttcataa acaagttacg ataaaaagaa
     4441 gcattctcgc cttccaaaat ctcataaatc attttagaaa aataggattc gaatcctttg
     4501 aatagatcac catcggattc tttcattagt tgtaacatat ctttagagct gtcacgtctc
     4561 attgtctcaa agtaataaaa ataaagatcc tctttatctt caaaatactg atagaaactg
     4621 cctctaggga tatccgctaa tttgacgata ttagcaatcg aagcttcttt taagggtact
     4681 ctagaaaact cgattctcgc agcctcgatt agtctttttt gtttttcttt aggcaaatgg
     4741 aaaaatgtct gtgtcggcat atggattctc ctttctttca agatgacaca ttgtcatatg
     4801 acgctatgtc attataacac ctcctacctg ttttgcaaga catttgcata gtttttttca
     4861 ttatcatccg atacattaaa aaagtgataa gaggaatcct tccatttgaa ttaatgagag
     4921 ttgcccatta aaatagccac atactaaaca aaggatgaga taaatggccc aatcaattag
     4981 tgtccaagac ttcaataaat tgcctctcga tgctgacagc atcgttttag atacaagaaa
     5041 taccttagat tacacaaaaa accacttaag ccactcgctt tctatccccg ctgctatctt
     5101 gccaagacaa ttaaaaaatc tagatccaaa gaaactttat tatattctaa gctatacagg
     5161 caggcgatca gaagcattag ccgatcaact tactgctaat ggttttcgtg ctgtttatat
     5221 cattggtggg atggaagctc ttcagtcgag tgttgcttga atattgcttg ttagattcaa
     5281 aagaggctgt gacaaaaaat cgtgtcacag cctcttttat accctgtctt tttttagtta
     5341 tttattcttc aaccttatca atatgacttg atagcctttt ctttttcgag taaactgatt
     5401 ttgttagtca tagttataac aatcatagca ataaaaggag aaggtaagca tatggcatct
     5461 gttttagtag tcaaaggtca tcccctaact gcagaagaat cgcgcacagt taaggcattg
     5521 acgtcttttt taacaagtta taaagaaaat catccagatg atgaagtgac tgttttggaa
     5581 ctttatcgcg atgatattcc ggaaatcgat gaagaattat tatcaggttg ggaagcatta
     5641 cgtgctggtg cagaattcac ttccttatca gaaagtcaac aacaaaaaat tgctcgtttc
     5701 aatgaattga ctgatcagtt ccttgctgct gataaaatcg ttatcgcaaa cgccttatgg
     5761 aatctaaata tcccaacaaa attaaaagct tggttcgata ccgtcaatgt agctggaaaa
     5821 acgttccgct atacagaaaa cgggccagaa ggattagtga caggtaaaaa agcactgcac
     5881 atccaatcta atggcggtgt atacaacgga caagactttg cctctcaata tgtaaaaggt
     5941 attttaaact ttgtaggcat cgatcaagta gatcagctat tcatcgaagg aatcgattat
     6001 gaccctgacc gtgcagatga gttgatgcaa aatgcattag ataaagctgc tgctttaggt
     6061 aaatcatttt aaaaattgag ataaatgcat acaaaagaga cagaggaaaa aatcttcaaa
     6121 gcagcatttg tgccttggat attttcccat ctgtctcttt ttgttattct ttctgctttt
     6181 tcaacggatt ttcttcataa agagaagaga ttgttgtgta ccattcaaaa acatgagtaa
     6241 tcactacttt agctgctgca taaacaggaa tccccaagat cacaccgatg attccgaaca
     6301 atttcccaga agtcagcaga actaataaaa tcgttactgg atggattgct aactgattcc
     6361 ctagtactaa tggagagatc aagcgtcctt ctattgtctg ctctactgca aaaacgatca
     6421 gtactttgat gatcatgaat ggacctgcta caatggctaa aaagatagcc ggaatcatcg
     6481 ctaaaaatga tcctaagtaa gggatcaggt ttaaaaaacc cgcaataatc cccaacgtga
     6541 cagcatactc taaaccaatg accgcaaaac caatcataaa catgattgcc acagcaaaag
     6601 ccacagttag ttgtcctctt atataagaag aaacttgact attcatttca ctcagcacat
     6661 tcaacgtcgg tttttgcatg cgtgtcggta aaaatttgac aaaataaggt gctaattgtt
     6721 taccgtcttt caatagataa aataagataa acggcatcgt cagcagagcc actaaaatag
     6781 tcgctaccgc gccgacaaaa cttccaagac tctgaactgt actcttagat atatcttgga
     6841 tcatatcgcc tgccgaattc atgaacttat cacctgctgt ttccaactgt tcgcgaaatt
     6901 ggttgaacag cgggtcccgc aaaatctcgg ttaatttatt atcaatcgta tctacatatt
     6961 gagggaagtt actgatgaag ctcactgttt gttcctgaat cttagggatg atcactacgc
     7021 tcccccatgc gattagtgca acaaccaaaa caaacagccc aatgatactg taaagccttg
     7081 gtacttttcg cttttcaaag taatcaacta ccggattcat caagtaatac aagattcctg
     7141 ctaaaatgat aggcagacct acgattgcta aaaattgcca gattggtgca aacaaatatg
     7201 aaacttttgt aaataaaaag acgatcagca atattaacaa tacaacaagt aaggctgtga
     7261 ctacttgatt atttaaaaac cagcgccaaa accacgatac cggtctgttc ttcttatttt
     7321 ttccttccat aattcctcct gttagttata aaaaatttgg cttcccaaac caatagcagg
     7381 cagtctatgc ggatgaagat agattccatt tgcaatttgt ccttcttctg gacaagcatc
     7441 aaaaatcaat gatacgtgag ctactgtctt taaattccca ttggccatcg gaccgacata
     7501 atcgatcgta tatacctgat catcaaaagc aattgttccg cctgctttca aagaaaaagg
     7561 ttcgtctttt gatacttctt gaatcaccga atattttcgt aaggcagctg ttgctgtttt
     7621 atcgaacaaa atcagcatgg gttcttcctt gtttattgct tctgtcccaa tttctgtaat
     7681 ctttgcctga atcattgcac tctctccttt aattgctttc aaaaacagta taacacattc
     7741 tcattcttta gccgtgtgga ataattatgt gatagaataa aaacgaaaac tatttcatta
     7801 caattaggag gaatcagctc atatgatcga aaagataatt ttaggaacct atacgcgtcg
     7861 cgaaagtaaa ggaatctata cgatcgacct tgatacagaa aaagaagaat tagccaacct
     7921 ttcattagct gttgaagaaa atagccctac ctatgtagca aaaagtaaag ctggcaatct
     7981 ttacacagtt actagtgtgg atggattagg tggtgccggt gcgtacgata aggattttca
     8041 ttttttgaat gcggtaacag agtctggcgc tcctttgtgt tatgtagcgg ttgatgaagc
     8101 acgtcaatta ctatacgggg cgaactatca taaaggtgaa gtaaatgtct accatatatt
     8161 aggagatggc gaactgaaag cagcagattc aatattccat caagaagcga caggtcctca
     8221 taaaaaccaa gatcatgcgc atgtccacta tacggatctg actcctgacc aacgattagt
     8281 cgtatgtgat cttggtacag atcgtgtgta tacttatgat gtgtccgaaa acggcaaatt
     8341 gaatcttgta actaccttca ctgcagagcc aggaacaggc cctcgccatc ttgtctttca
     8401 tccaaatgga caattcgctt atttatttgg tgaattagac agcacagtcc gcgtgctttc
     8461 ttataataaa gaaacaggtg cttttgaaga attacagaaa atatcgacct tgccagaaga
     8521 attcgacggt gaaaatggag gggcagctat ccgcatttca aatgatggca agttccttta
     8581 tgcttctaac cgaggacata actcgattgc tgtattcgca gtttttgaag atggttccca
     8641 cattcaaaac aagcaaatca tctcaacaga aggggatttt ccccgcgatt tcgcactaga
     8701 tccaagcaat aattttgtcg tgtgtgccaa tcagaacacc gataatctga cattatatcg
     8761 ccgtcatcct gaaacaggat tactggaatt actgaaaaaa gatgtctatg taccagaatg
     8821 tgtctgtgtt tattttgatc gttagtaaga aaaggagaat gaaatgaatc agcaagacgt
     8881 attagacaga ctacgggaag aactaaatat tcctttcttt gatgggaaaa tcgaagataa
     8941 agagtatagc gaagaggaat atcagaaact caaagccgat ttacagaact actttgaaca
     9001 atatgtacag aatgtagaaa actaatcagc tttccatact atctgaaaag aacatcagga
     9061 caagactttt ccgtctatcc tgatgttctt ttctacaaat aaaaaaccgc cgagatggtt
     9121 agactcgacg gaaaaggagt atttactcga ttttgagtaa gtacaaggtt gttgttggtt
     9181 ataggtatgt cattatcata aaggattttg atcactctat cataaaggta atattacatt
     9241 tatattagat aactctagtt tttattgtta tcaaagattt cttttatttt ttcaacaaca
     9301 aattagtcat tttttggatg gcagctgtca attggtctgt cgcttggtct tgttttgctt
     9361 cagatgtatt gaatagatct tcatctaccc ctgattcaag atcgatactt tggatcattt
     9421 cttcacagcc tgctacatat gaaagataag ctttttcaaa atttttatga atgcccattg
     9481 cttttgctgg tggacgcaaa gtactgactt tcataagcat tgcccgatat ttttttgttc
     9541 cttcttcaaa taacaggatg atctcttcaa gagtcgattt gtccagttca cttgtttttc
     9601 cttcatcaat tgcgtttctg atcacttcat atttcggatg cattccttct ccgattgctt
     9661 ctgtttcctt gacgatttga tcgatggact gcacataata gccaatattc ggtaacatgt
     9721 tcgttttcct actttctcca ttgttgttat tatttattct acttgttttt atcctcaaat
     9781 gacaagtact tgaaaaaatt taatggtttc tatacagctc gccattctta ttcgtgctca
     9841 aagaaaccat ctgctaaact atattgtttc cctgcgacaa tgtcatattg gatcaattga
     9901 tattcgtcgt aaatctcttg ttgcgagcga ttgaattgcg cttctttata ccactgtccg
     9961 ttttgatagt acagttctcg ttcaaacgcc ggaagttcct gttctaatga taaaagcagc
    10021 tgataaaagc catttgttgt ctgattcgtc tgttccatta gattcgctgc aaaataaaac
    10081 ggactggtga ttgcatcgtg agtcgtttgc ttttctaatt ctcctttact gtcgaacata
    10141 agaaattgtg tttcatgcaa tgtttgtttg tcattttttg cttggatcgt atctgaatag
    10201 atccctggaa gatgatcccc ccaaaaaaca actaaagtcc ttctagaaag attcttcaat
    10261 tcttccgtga actgcttcag tgccgtgctg ctataggaaa tatcttgcag ataattctct
    10321 aagtcaagtg tcccacttcc atctgaagtt tttgcaggat agtctagatt atcatacttt
    10381 ccatcgtagg gcatatgtgt ctgcatcgtg actaaatgaa tgaactgagg tgttttttct
    10441 tccttgagaa gtgtcattac ttctttgtaa gctgactcat cagaaatata tggattattc
    10501 tctatcgtat ccgtataggt catcgtacgc tcgctgatga actggtcaaa tcctaatgtc
    10561 tgataaacat cctctctttt atacatcgaa gtattgtatg gatggatcgc tgtcgtctgg
    10621 tatgattgtg cgtttaacgc tgaaacgata gaaggaagct gatccatttt tggtacaagc
    10681 atcgtgtaag gggtggtgag ttgcgcatta aataacgcca tagaaaaacc agtcaatgct
    10741 tcaaattcga tatttgctgt tccaccgcca tagttttgag aaagcatatt gccactatat
    10801 gtttgatcag ctacttcata ataatctgcc aatggctcac cagatacttc tacgccgttt
    10861 aatcgactag gatctgagaa actttcactc atcacgaaca cgatgttcgg cgactcttcc
    10921 tctacagttt tatttttttc atcggctagc ttctggtatt tttcagtgat ttctttgatc
    10981 ttttctttcg aatatccttc aggttcatcc attggttcta ccttcagatt gtacaaaaac
    11041 ccaccgataa aaccagtgtt atagtagttc attttctggc tgtaaggtat ccatagtgcc
    11101 gttttattat atgcttttcg caacaaatta tcgggattgt tgaaattact gatataccct
    11161 agcagtccaa ttgccacaag cagtgtcgtt aatcggatca attggaatcg ccttcctttt
    11221 ttcaggcttc gaaacatgta ccagcaaaac aatcctatca cggttcctgc ggcagctaag
    11281 atcactgtaa acagcatagt gccggtcata tctttcagca atccgatttc agtgatcatc
    11341 ttcaaatcgt ctggataaat cggttcttgc cgataactca ttttcatata atttgcaaaa
    11401 cctaatacac cgatggctac gacatacgta agggaaccta aagggacaga tcctgctagt
    11461 gcaatcagaa aaataagaat aatcagcaag acgagacagg ctaagaagaa tttttccgta
    11521 tgccaagaaa aagcaaattt caacgcaagg tctacggata gatcattttg acaccactgc
    11581 aaaaataaat tactaaaaac aacaagaaaa aagatactga tgattgctgc tgttcctttt
    11641 aaaatctttt tctgtttggt cgaaagtctg cttatatatc ttttcaaatg cttgctcctt
    11701 catttctatc aataaaagaa tgttgcttct cttattttag ttgtacgaaa ttcgaaagta
    11761 aagaacggaa agaagaatta atgaaatcca aatattctct ttctttatgg cctttctggt
    11821 ttctttaata agcggacctt tcgtactcca gaaatttttt ctagctgttg tttcacttga
    11881 ttgagctgtt caaaatcagt actgtctatg tcaatcaata tgtagacatg ctcattctta
    11941 tggttacgcg atatatctgc gatcgctagc tcgttctcat tcagcagaga aaatatctct
    12001 gctaatatat tggttttctt ttgataaaat atagtgaatc gaaacggcgc ttggaaaaac
    12061 attcgtgcgg atggataatt gaccgcttct ctaaccgtac cgaacaaaag ataatctttt
    12121 aaggcttcaa ctgccaaacg tccgctgtct gccaaagctt cctgagtcga tccccctaga
    12181 tgaggcaaca taagtatacg gtcattttct aagaactctt cttctggaaa atcagtcaag
    12241 tatttagcca gatgttgttt ttccaatgct tgcataacag catatttatc aacaatttca
    12301 cttcttccta cattgataag tacagcatct tttttcattt tttctatatt cgcctgatcg
    12361 atcaatcctt ttgtatcttc tgtcaacggc agcatgacta cgatgtaatc cgaggtagaa
    12421 agaactgttt ctaaatctgc ttgccgaaca taatccaact gggcatcgcg gatagaataa
    12481 cccaagacat ccatccctaa gctatagcaa cttagcgcta cttttgtgcc tatcgctcca
    12541 agaccaagaa gaccgatggt tttgccttgc aattctcgtc ccacataagc acttcttttg
    12601 ttttctgcct gttctaaaat attaggacct gttagtgttt gtaccatacg acttgcttcg
    12661 attatcggac gggaagataa gagcaaacag cacaaaacaa gctcttttac tgcattagca
    12721 tttacacctg gtgtattcat gacgatcgtc ccgttttcag aagctttttc aacgttgatc
    12781 gtgttcaccc caacaccagc tcttgaaatt gctagcaaat ctggtgtaag ccattcatct
    12841 ttcactttcg tactacgaat aactattcct tcggctggca aatcatctat tattttgaaa
    12901 tattcccctt gtaacttttc tatctcttgt tctggaatag catcaatcaa atgaacgtga
    12961 tacataaaac cccctcctta ctaacaagta tctcgaaatt tctgcaatta gacaactgtt
    13021 taccatttga cttcctagaa gcaaaaagag cagttagagc agagtaggct gagtgataaa
    13081 aataaggcta tgacaagtta ctgccataag ccttattttc gagagcaaaa tattgagggt
    13141 gagatatctt gataaatggt gttccgttag ctgacattga taataagact aaatttcaaa
    13201 aaagttgaaa agcaaatttc gtcaatctct tcttatttct taaaactaag tggctttttc
    13261 acaacctctt tttatctaat aaccactgtt tccaactcaa ctaattttgc ccacgtttca
    13321 atttgatctg ttgttagatt tagcgagaca acggtatgat gaccgccacc tgcctgaatc
    13381 catgaatgga caccttcatg gaaattcggt ttagttttcc ataacacacg tgcaacaggt
    13441 aaattaggtg cttcagtcgt tggttcaaag gcttctactt cattgatcag cagtttataa
    13501 tgcgtaccga aatctgccat cgatacgact accccttctc ctgctttccc atcaaataca
    13561 agacgcgccg gatcttctct atctcccatt gataaaggag aaacaacgat tcttggtttc
    13621 gtcgcagcaa gcgtcggatc tacttccatc atatgggatt ccaagattgc ttcttggcca
    13681 ctagctagct cgtaagtata atcttccatg aatcctgtat ctttccctcg agccatgatt
    13741 ttcagcaacc gatcaatcgc tgcagttttc cagtcgcctt ccccagcaaa accgtatcct
    13801 tctgccatca aacgttgtac agctagtcca ggtagttgtt tcattccata caggtcttca
    13861 aaattagtcg taaaagcgtt atagcctcct tcttctaaga aacggcgaat accgatttcc
    13921 tgctgagctt gtacttttac atgttcctcc catgtctttt cttcataatc accatagtcg
    13981 aaggtataca attccttgta ctcttcaaat aattgatcga cttcttcgtc tgatacgcga
    14041 tcgattactt gtacaagatc tccgatacca aaataatcaa cagtccaacc aaattgaatc
    14101 tgtgcttcca ctttgtctcc ttctgtgaca cccacgtttc tcatgttgtc accaaaacga
    14161 gccactttta ttccaaaact ttcattatag gctactgcaa catccatcca atcagcaatc
    14221 tctttttgga tctcaggtcg tttccagtag ccaacgacga ttttattttg tttatttaat
    14281 cgagcattga tgaacccata ttcgcggtca ccatgagcgg attgatttaa attcatgaaa
    14341 tccatatcga tcgttttcca aggaatgctt tcgttatatt gcgtagctaa atgaagcaat
    14401 ggtttttgta gaagctttgt cccgcggatc cacatttttg ctggtgagaa agtatgcatc
    14461 caagtgatca cacctgctac ttcttctcga taattgacct ctttcatgat ttttgtgatc
    14521 gtatcagcag taactgctaa ttcttgaagg cggattggat aaggcaattg gccattttca
    14581 ttcagttcat cgaccatttc ttgtgcatgt ttctttactt ctcgcagtgc ttcttcccca
    14641 tataaatgct gtgatcctac aacaaaccaa aattcttttt ctccaatatt caacataatt
    14701 agccactcct tttatttgtt ttgtccgtaa tacgcatttt ttccgtgttt tcgtaaataa
    14761 tgtttatcta aaatccgttg aggcagctct tctgaaaatg aattgagctg tctggtaaat
    14821 aaattcatct tgcatacttc atctagtacg actgcgttca ttaccgcact ttgcgcatct
    14881 ttcccccaag taaatggacc gtgtccgtgt aaaagtaccc ctggaattgc taagggatca
    14941 attttgcgtt ctttgaatgt ttctatgata acttttcctg tttcatattc gtacccgctg
    15001 tcgatttcct gttgtgtcaa aaatcgagca caaggtaccg atccataaaa agtatctgca
    15061 tgcgtcgtcc ccatcgcagg aacatccaat cctgcttgtg cccagatcgt cgcccatgtc
    15121 gagtgagtat ggacgattcc tccgatttga ggaaatgaac gatataaaac agcatgagta
    15181 ggcgtatccg aagagggatt gagtttacct tcaatgatat gattgtccaa gtccacaacg
    15241 accatgtcgt ctgctgtcat ctcttcataa ctgactccgc taggtttgat aacgaaatat
    15301 cgtgtttcag gatcaaaagc gctcacattt ccccatgtat atttgacgag tccgtgttta
    15361 ggcaagtcaa gatttgcttg gtatacttct tctttcagtt gttccagcat tttctatcac
    15421 tcctttttct tgcaattgat gaatcgctgt tttttcaatg tcgatcccct cacggtaacg
    15481 tctcataaat atctgatagc ctgctatttc ttctgctgaa ggtgtgatgg tgattccttg
    15541 gtcttgtcca aacacgtctt ctgccaagaa gttttctaaa gacttcccat gtcgatccat
    15601 catataggct gctaataacg cgattcccca cgctccacct tctccggctg tgtccatcac
    15661 tgtaactggt gcctccatag cagatgctag aatccgctgt ccaacttctg gtgttttaaa
    15721 aatcccccca tgccccacta aacgatcaat ttggacattc tcagatttca atatatccat
    15781 tccgattctc attgcaccaa aagcactggc taaatggatc cgcatgaaat tcgctaaatc
    15841 aaaacggcta cctggtgtac gtacaaataa tggccttcct tcatttactc ctgtaatgtt
    15901 ttcaccggaa aaataaccat aagaaagtaa tcccccgcaa tccgtatcgc cttctagcgc
    15961 tttgttgaat aataccgtga ataatttatc tctgcttatc tccataccca aagaattggt
    16021 aaattcttca aaaatactga cccaagcatt gatatccgaa gagcagttat tcgtatgaac
    16081 catgcctact agttctcctg aaggtgtagt gaccatgtcg atttccggat ggacattttc
    16141 tagttctttt tctaatacga tcatagcgaa ggcggaagta ccagccgaaa tgttccctgt
    16201 ccctttggct acactgttcg tagcgaccat accggttcct gcatcccctt ctggcggaca
    16261 aaccgggatt cctggtctca aatttcccgt agggtcgatc agataagccc ctgattcgct
    16321 taacttgcca gcttcttctc ctgctactag aactttaggc aaaatgtgat ccaagtcaat
    16381 cgctacgtgc gctttttcga ttaactgacc aaaaatattt ttcatttctt gatggtaggt
    16441 tttcgttgaa ggatcgatag gaaacatgcc tgatgcatct cctacgccta gtactttctc
    16501 accagtaagc tgccaatgga cataacctgc aagcgttgtc aaaaaattaa tttctttcac
    16561 atgttcttct ttattcaaaa tagattgata caaatgagcg atactccatc tctgcggaat
    16621 attgtattga aatttttccg ttaatattcg ttctgcttct tcagtgattg tatttcgcca
    16681 agtacgaaat ggtactagta actgttcctt gctatcaaat gctagataac cgtgcatcat
    16741 tgcactgaac ccaatcgacc cgattgtcgt aagattctcg ccatagattt cgaatacttc
    16801 tgctgccatt tttcggtaac tgacgcgcag tcctttccaa atatcttcta atgaataggt
    16861 ccagatacca ttttctagtt tgttttccca ctcataacta ccagcggcaa taggagtaaa
    16921 agatgaatca atcaatacag ctttgatcct agttgatcca aactcaatcc ctaaagatgt
    16981 acgaccatct atgacatcta acatactttg cgcatttact tccttcataa tgatttaact
    17041 ccctccttct cgtcaaacct gatcaaaccg tctttttagt agcgcttaca atgattattg
    17101 tatacttttg tacgtacatg tcaagcagtt atttacaaga atacaataaa aaacacttgt
    17161 tttgtacgta cataagttat aaaatgaaat tgcttacaaa atctgatcaa ccgccttctc
    17221 gaaattctag aaggagagaa tacttatgaa aaaagaaaaa aaagtttcct catcgtttat
    17281 ttattttttt ggcgcatttg gcggcattct atttggatat gatattggtg ttatgaccgg
    17341 cgccttacct tttttacagc atgattgggg tttggcaggt aaagcttctt tgataggatg
    17401 gatcacgtct tcggtcatgt taggtgcgat ccttggcggc tctttatctg gtcttctttc
    17461 tgataagctt ggacgacgaa aaatgattct tctttctgca cttattttta tggctggttc
    17521 tgtcctttct gcatctgccc ctcacaatgg ttcttatttt ctgattgcag caaggattct
    17581 tctaggttta gctgttggcg ctgcatctgc cctagttcct gcttatatgt ctgaaatggc
    17641 tcctgctaga ctaaggggaa gattgtcagg gatcaatcaa gtgatgattg cttctggcat
    17701 gctcctttcc tatgttgcag attatttgct aaaagggttg cctgaaacga tggcttggcg
    17761 cgtgatgtta gggctcgctg ctgtccccgc gctgatttta tttttcggtg ttttagctct
    17821 accagagtca ccgcgttttc ttatgcaatc tggccgcttg gaagaggcaa aaagagtatt
    17881 gaactatatt cggacaccaa aagaagctga acaggaattc gaacaaatcc agctgaatgt
    17941 caaacaagaa aagacaaccg gaacttcttg gcatactttg tttttagaaa aatatcgttc
    18001 cttagtcatt gccggtattg gtgtagcagt attccagcaa tttcaaggag ctaatgctat
    18061 tttttactat attccgctga tcgtagaaaa agcgactggg catgcagcga gcgatgcatt
    18121 gatgtggccg atcatccaag gaatcatttt agttgctggt tctttgctct ttttggttat
    18181 tgcagacaag ttcaatcggc gaactttatt gaaaataggc ggtagcgtga tgggactttc
    18241 tttcatccta ccagctgttt taggaactgt actggatgct catacaaatt cgttgttgat
    18301 tctcttgttt ttatgtattt atgtcgcatt ttattcttgc acatgggctc cactgacatg
    18361 ggtaatcgta ggcgaaatat tcccactagc tgtccgcggg cgagcatctg gcctagcctc
    18421 ttcttttaat tggattggtt ctttcctagt tggcttgctt tttcctgtga tgactgcttc
    18481 tatgtctcaa gaaatcgttt tcggcatttt tgggatcatc tgctttttag gggttttatt
    18541 tattcaagag atcgtaccag aaactcgtgg gaaatcttta gaggaaatcg aacaaagtgc
    18601 atctaaaaaa acttatccta aacgtatttc tatccatcat tcttaaagag gttgtgacag
    18661 aagtggtcag cttcaagaaa taagaaggaa ccgcttagtt tccagtcaca aggaacaatt
    18721 tcaaaaaaca gcttctcatg tttgatgaat attgtgactt gtgaccagtt ggtaggagaa
    18781 caccgtttag tggagaggtg gtgaaagaaa cgttcagcct tgagcgatga caaaagctct
    18841 cacaaacatt gcgacgagta accgtaggag caataagagg cggtaaaaac ccgtctctta
    18901 tttttcgttt tctttcactg tttcccgttc aactagtaca ggttcataga gaatatttgg
    18961 ctgtgcctgt cctttttcaa tcgttgtgac gatccaccgt gcggcatctt gtcccaactt
    19021 ttcttttgga tgcgtcaatg ttgtcaattt tttattccct aaatggctta aagaagaatc
    19081 gtctgttcct acgatcgata ggtcatctgg aatatgatag ccattttctg tcaacttatc
    19141 tagcattaaa ctagctattt gatcgttata gcaaatgatg ccatctaaag cttgttcttc
    19201 tttcaaccgt tgtactgttt tttcagcgat tgtttctcgt gtttccgtgg tgaaagtaat
    19261 gatatcttcc gtcaaaaaac gcacattata ctgttcacac gcgctgataa aacctttcat
    19321 cctgtatttt ccttgaagat cgtcgatttt tgtgatgaac aacagacgct gatgtccttt
    19381 ttttatcaaa tattctgctg ccataaaacc gactttcaca tcatctaaac aaatataaga
    19441 ggcatttaac tcttcataag cagcattgat catcaccatc ggaatgcctt gttctctcaa
    19501 agcaacataa agtgctaagt ttgggttata ctgattactt ttcgtaggct caacgatcaa
    19561 accatctacc ccataagcaa tcattttctt caaacactct ttctccaatt cgtgatcgtt
    19621 attcgtactg gctaaaagca atgaataccc agattctcgt aattcatttt cgattcctcg
    19681 gataatcgac ggaaaaatat aatcagagag atatgtggtg atgacaccga tcgtttttgt
    19741 tctgttcaat ggtgtttttt ctttcttata gctgtcatct acatatgtgc ccgacccttt
    19801 ttctttacgc agatagccct catttaccaa cacagcgatt gcttgccgaa tcgtatgtct
    19861 gctgacgtca tatatttctt gcagcttgaa ttctgaggga atggttgtat ttacttcgta
    19921 ttcctcacga aggatctttt gttttatctc ttctgcaata tcttgatatt ttgccatttg
    19981 ccttgcccct ttttatttgt acgtacatat atcataacga gtctgcaagg tttattcaag
    20041 caaaaatcaa ggtttcttgt gctcataagg catacggaac aggttcacca aattctggaa
    20101 atccttgctc attccacgta aagcattgcg cgttcgcgtg ccgattagga ttgtctaacg
    20161 gatccccttt ttggttcttc tctggtcgag catgatagat caaaatatca aagcacccgt
    20221 cttctgaaac cgtaaacgag ttgtgaccag gaccaaattg cttatttttt ttagaagaaa
    20281 cgaatactgg ctccgataat ttatgccatg attcttttaa taaaagattc ttgtgctcat
    20341 cagcccacag caggcccatg gcatagtttt catctgttgc actaccagaa tacgtaatga
    20401 atattttccc attgcgagta aggactgctg gaccttcatt tactgaaaaa ccccgttttt
    20461 cccattcata ctcaggtata gaaaggagga tctgcttccc ctttaacgtc caaggattat
    20521 ccatttcgga tagataaaga ttagaattcc cagtaatttc aggatcttgt tgggcccaca
    20581 cataatatag ctttccttga gaagagaaag ttgttccgtc taaactgaaa gtttcccttt
    20641 tcgtttttat ttgtcccttt tctatccaat ctgtattcat tggatctata tgctgatttt
    20701 caagtacgaa catgcggtga tgatgagatt catcacgtat agttttatga ttgcttgcag
    20761 caaagtaaat ataccatttt ccattgatat aatggacttc aggtgcccag atcaattcac
    20821 tcatcggtcc ttcttcatga gcctgccata caatcaggct tgcagcatgt tctaattcat
    20881 tcagtgactt tgcccttctt aattcaatca cttggtagcc tggaaccgat cctgtaaaat
    20941 aataataacc atctgtatgt ttatataccc aaggatctgc ccgttgccga acgataggat
    21001 tattataaag tgtcttcatc ataacaaatt tcctcacatt ttctttattc taattacatt
    21061 ccaagagtat ttttctatcc ctacatttaa ttcgtcatgt ttttctattg aaaaatagtt
    21121 tatttcaggt tttatttttt ctggttcttc acgtgtattt ttgtccaaca gatcgctact
    21181 ggttaatgtg tagtgctctc cttgatctag caaattgaaa tcatgttcaa tcgttatctt
    21241 ttgttgttca tttgtgcgat tgatcaagaa aatagtcagc tgattgccgt tatctacgat
    21301 cacactgtcc acataaggaa cattttttat cttttcacaa tcataaacag ggcaaatgat
    21361 ttgttgtttc aatacttgac ctttagcata tttcgataag tgttgcatca cataataagt
    21421 tggattcctc catgcttgtc ctttagcatc tgtcagtatt aaaggtattg tgtttactaa
    21481 caatgattga caactaatct ttacgcgatc tgcgtgtcgt aaaatagcca gccctaatga
    21541 accaaataat aatgtatctt ccatagtaaa gtaacaccaa tcgatgggac taccgacttc
    21601 aaaatcccta tgtctttttt ccggttgggc atgtacattc cattcatcaa acgctagata
    21661 cattgttttc tcacttctca aatatccttt tacataatca caagtagcaa cgatttcttc
    21721 aatttgacga tcgaatcgat aagcttttgc aaggtatgtc gctgtatcat cacgctcatt
    21781 tttaggaggt ttagtcaagt cttcttcatc atacttatca atatagttat gcaaagctaa
    21841 ataatctaca ttctcataag cttcttctaa tgcgatacga tcccattcag ggtacgatgg
    21901 taaacgtggc gtagagcttc caactaagat tgtttcaatt gaatcatcca ctaacttcat
    21961 gacttttgag gcttcatttg ctaacctacc atattcataa gcactcttag cccccacttg
    22021 ccatggaccg tctagctcat tccctaaaca ccataattta acgccaaaag gctttttttg
    22081 cccatttttt attcttaaat cactccagaa ggttcctttt ggaaaattac aatattctac
    22141 taaatttttt gcttcatcaa ttccttttgt tcctaaattc accgtgaata tcggtttcgc
    22201 ttgtacatga ctgatccatt taaaaaattc gtggagtcca aaagaatttg gttctatacc
    22261 tcgccatgct aaatcaattt tttttggtcg ttgttctttc ctacctacag tatccaccca
    22321 atcataacca gatgtaaagt ttcctccagg atagcgaatg acacctaatt ctaattcctt
    22381 tacataagag aggacatctt gtctaaaccc gtcaccatca gctgtttcat ggcccggttc
    22441 ataaatccct gtatagacga cacttcccat atgctcaaca aatgagccaa acagccgaga
    22501 actgatctct cctaccgtaa aatcctctct gatttttact ttcacttctt cgtccaacag
    22561 ctttccctac ctttcatttc ctatagtcaa gataatagat acaagtttcc atacgccacc
    22621 agcaaagata aaaataaaag gagggaaaag aaatatgagc agtacaaatc ctaataacaa
    22681 tacgcaacaa agaatatttc tcaaaaaatc aaaaaatact ttccatgcac tttgttcaaa
    22741 aatttgtaaa aatgtgatat ctttgttttc agaaatcaca tatatccagg ataaaagaaa
    22801 catggaataa ataagtaaaa ctacatatcc actaattgaa agtacgattg tctgttcttc
    22861 taataattga ttaacaagaa aataaataat gatcgttaac agactaagga acaagttctt
    22921 accaaaatgt tgctttattc cttgaaagaa aaaataaatg atatttcctg atccctcacc
    22981 tttccattgc gccattacat aaaaaacagc acatgtagca ggcacgatag taataacagg
    23041 caaacacacg attacccaga gaatacctaa taagatgtaa tcagaaacca caatcaactg
    23101 tccataaagt ttagtctcaa ctattttcat cttcctcact ctttcattcc agacatagct
    23161 gttccttgaa caaaatattt ctgtgcaaaa atataaacca ctagtaatgg cagcattgaa
    23221 ataaccgttc cagccattac aggtccataa aaagaaatgt tctgccctgt aaataaagct
    23281 aaccctgctg gtaaagttct catttttgaa ctacttgtca atatcaatgg ataaagcaag
    23341 tcattccaac tattcatcag cgtgaaaatc cctaatgata aaagagtagg tttgctcaat
    23401 ggcaacatga ttttcaaaaa aatattaaac tcacttaatc catcaatgcg tgctgcctct
    23461 tccaaagaat ctggtaaagt aataaaaaag gaacgcatca tgaagatacc aaatgcagtt
    23521 gtcatacgag gaatgatcaa acctgcataa gtatcaagca tgccaagcaa attgacttca
    23581 ataaatagag gaatcatgaa gacttggaat gggatcatca ttgtcagcaa aacgaaatag
    23641 aacaaaactg attttccttt gaaacgcata cgagcaaatg cataccccgc aagagaatca
    23701 aagaatacag aagtgatcac tgtccctcca gcaaaaatca ctgtattttt gatgtaatct
    23761 aataaaggga tcgttgtcca aaccttaata tagttatcta gggtatagct atctgcaaat
    23821 attctaggcg gaaatgagat aatgtctttt tcgtgtttaa aagaagaaat aatcagccac
    23881 aaaaaaggaa acgcaataac caacaatata actagcatac taatcgttcg aatgattttt
    23941 ttaccactaa ctgcttttcg actattcaca gtaactgtaa tcgagctttc tggtgccata
    24001 caggtttccc tcctatttca tttgtttttc tttccgtgac atgtacacat tagtggagat
    24061 agctatagtt gcaacaatga taaacaaaac cgaagacagt gctgatgcat agcccaattc
    24121 ataaggtgct gtaaatcctc gactgtaaat atattgaaca gctgtttctg tcttaaattg
    24181 tgggccacca gcggttgcaa catatacttg gtcaaacact tgcatcgaac caatcagatt
    24241 cgttaaaata caaaaaccta aggagggaac gatctgaggt agcgtaatgt taaaaaactg
    24301 ctgtcgattt gttgcaccat ccatttgagc agattcatac aaagagggag agattccctg
    24361 aatagcagtc aagagaatcg tcatagtaac accaaaattc ttccaaacag tcatgatggc
    24421 taccgtcggc atagcaaggg ttggatcgcg aaaaaattga gggatcggca agccgacttg
    24481 tgaaaacaag taaggaatcg cccctacatt cggatcaagc aacatagaaa aaataatcgc
    24541 aattgacgtc aatgaacaaa taactggaat gtaaaatgtc gaacgacaaa aacgattgaa
    24601 tctggtattt ttagataatg ctactgctgc taataaacca acgataattt gtgttggcgt
    24661 ttcgagtacg gtgaaatata aagaatgaat caacgaatta actgctcgtt catcactaaa
    24721 tatacgtgtg aaattttcaa aacttacaaa atttcttgat gtaaagaaaa tattcaaatc
    24781 tgtaaaacta atagcaaatg ttcctaaaag cggtatgaca gtaaataata ataaaactaa
    24841 aaaagatgga gttaaaaaca aatacgcagc acgatcagga cgattccaat atttggtgaa
    24901 tccgttcata tagtccacct catctttcat tttgataaaa tatacaatct tggtttaaac
    24961 gaatctgaat aagatatccg aacaatcgct gtgatttttg caataacacc tatctgcaaa
    25021 tactaggtcg atcattcaga tatctgtatc ttgccaacag tctatcctgt ataaagttct
    25081 gtactatttt tgcagtaatt gattgatggc atcatctgca tcgttcatga gtgtctcagg
    25141 atcttctcct gctaataatt tttcaatcag tggattgatg atatcgttat tgatcgcaga
    25201 gatttgggta aaacctggta aatatggctc tgcatagtcc atttgtttcg ataattcaga
    25261 tacaatagga tcatttttta cttcttcatc ttttgctact gaatccaagt aggcaggaaa
    25321 accattttcg atactccatt ttttaccaat ttcagttgta ttccaatatt tcaaaaactc
    25381 atagacagct tcttttttat tattatctgt acttgccgga atggcatatc ctacgccatc
    25441 taaaatagct gtttttttgt ctgaatcact cccttgtggt aaggtagtca cattataatc
    25501 aatctcgttt gctttcaatc cgttatttaa ccatggccca ttgatttcaa tggctagttg
    25561 accagcattc attaaattgt ccatttcggc gccagaaatc gattctggac cagtcttgtc
    25621 tacatggatc attttttgga tcgcttttaa cgttttaagg ttctcaggag acgcaaattc
    25681 agacttagta taatcatcgt tcactaattt accgccattt gctaacatcc agttatataa
    25741 cggtgcagtt ccatccttat tgaagacaaa acctgataca tttttactac tatcagttaa
    25801 ttttggtgcc atttctgtca attcttccca agtagtaggt ggttgttcag tatctaatcc
    25861 agcttgttta aacaaatcat tattccaata catatacatg ccttgtacct gcatggggac
    25921 aaaatactgt ttaccttcta cttcacctaa ttcaatagcc gtttctttaa aatcagattt
    25981 atctactcca tcatattccc agaaatcgtc taatggttgt accgctccgt tttctacata
    26041 ctgtgcaaaa tctggataat ttaatgcaat aaagtcaggt gcttttttag aagaaatcgc
    26101 tgtaggaagt ttttcattca aattggccca agtcatgata tccatttcaa ttttgatgtt
    26161 tttatcattt gttttattaa attcattaac gatttcttgc aatatttcac catcagatgc
    26221 agtaaaccca ttccaaaaag tcaaagtcac ttctttatca gaatcagatt ctgctgaact
    26281 tccgccaccg caagctccta aaatacctgt tgcagctacc aacaaagagc caattaacca
    26341 ttttttacct ttcatttttt gttcctcctt catctgataa acgacatctg accacattcc
    26401 aagatagcgg tttcaataaa caattgattt tcccatcttc agcttttaca tttgttgaat
    26461 gacttggttt tacttgttca cttttaggaa gattagttgc ttttgtatca aatccactca
    26521 tttcagaaaa atcaatcact ccctctaatg ataattcaga caagtgaaca gttagattca
    26581 tttcttcttc tccacggtta actgcaaata tgacaagttc tttgtcattt attacggcta
    26641 tactttctaa atacggcact tcttcaaaat cttccgtcgc atagtttgct gaacgaattt
    26701 gtgggcttaa cacctctcct tgtccataca cagcagcttg cataaatgga taatagatcg
    26761 tctgtctcca agcttctccg tttgtttctg tcctgattgg tgcaataaca tttaccaatt
    26821 gagcaagaca agcaatcttt actctatctg catgtttcaa taaagtgatt aatagacagc
    26881 ctaatagtaa tgcatcttca aaattatagt tatcttctag taaaggagga gcaatctgcc
    26941 aaggcgctgc ttgctcatct tgttccgctg aatgatacca aatattccat tcatcaaagg
    27001 acaggttgat ctgcttctta ctatgtttct tcgccttgac tgtatcgcac atcgctgtca
    27061 cttcagaaat gaaccgatcc atgtctaagg aacgtgcaag ataatgagaa agatcatttt
    27121 tttggttgcc ataatattga tgcagagaca aataatctat ttgatcgtac gcttgatcaa
    27181 gaactgttaa ctcccaatca ccaaatgtag gcatttgccg attcgaactt ccgcataaaa
    27241 ccacctcaat tgaatcatct acgagtttca tcgccttagc cgtttcctct gctaaccgtc
    27301 catattcttc cgctgtttta tgtccaatct gccaaggacc gtccatttca ttccctaaac
    27361 accatgtctt aattccaaaa gggctctctt gaccattcga acgccttaaa tcactccaat
    27421 aagttccttt aggaaaatta caatattcga ctaaattacg agctgcatct actccacgag
    27481 tacccagatt gacagccata ttgatttcgg cccccacatg ctgacaccag ttataaaatt
    27541 catgaatccc aacttcattc gtttcaattg tccgccaagc taaatccaac cttctaggtc
    27601 tatttgctat gggcccaata ctgtcttccc aacgaaatcc tgacacaaaa tttccaccag
    27661 gatatctaat catgggaatg ttcaattctt ttaccaagtg aatgacgtct tggcgaaatc
    27721 cacttttatt agctgatgga tgatctggct gataaatccc ttcatatact gctcgtccca
    27781 tatgttcaat aaatgaactg tacaaccgcg gatcaacttt gcctacacgc ttgacactac
    27841 taatcaacat tgtggcttcc ataactgacc tcctttaatt tatacatgaa taatacacct
    27901 cgttgaaagc gttgtcaata atataaatgt taaacttact tattttttat cgattttaat
    27961 taaccaaaat attaataatg attaaaacaa ataatttaat ataactttta ttaacaaata
    28021 tgttaatata taagaaaaac cttttaagag gtgatatata tgcaactaca aataaacgaa
    28081 gaatccttac cggtatatga agcattagct agtaaaacaa ggatcaagat catccagcta
    28141 ctttccaaaa aaaagatgaa tgtcaaagat ttggcaaaag aacttggagt gagcagtgct
    28201 atcacgacga tgcacgtgaa aaagctagag gaagcaaaca tcatcaaaac agaaaaagta
    28261 ggacaacaaa aaatttcgag ccttcgtgtc gataaaatcg atatcagttt tccagaaaaa
    28321 atattcaatg cttttgatac gaaagaaaca tcgataccta ttggtcacta tacaaattat
    28381 gcaattgaac caacatgcgg tttagctacg atccatgatt ttatcgggaa agtggatgaa
    28441 ccacgctatt ttatggatcc tcgaaggatg gatgcccgca ttctctggtt taccagcgga
    28501 tttgtcgagt atcaggcacc taatttttta aatacagagg atacattgga gatgttggaa
    28561 gtttctgtgg aaatttcttc tgaatttcct ttttcaaatg acaattggcc ttcagatatc
    28621 actttcagcc taaatggtgt ggagctagga acatggacga gccctggaga ttttgctgat
    28681 atccgcggta aatatacgcc tgattggtat ccagataatc ttaatcaata cggcttgctg
    28741 aagacgatcc gaattaccaa acacttgacg aatatgaatg gagaaccctt gtcaaacatc
    28801 acgatcaacg acatccctaa agagcaagac acttggcatt tgcgaatcga agtgaaagac
    28861 gatgccaaac atgtgggggg ctgtacttta tttggtaaag gattcggtaa ttacgatcag
    28921 gatatcaaat taaaagttta ctacagctga tatttttctt ttctatttta taaaacaaaa
    28981 acagccaatc cctatgaagg gacggctgtt tttgctttat tgttatttcc agaaatcatc
    29041 caaaacggaa attggcaaat gtcgtttatg ttgtgtcttg ttccaccatg cttcgatttt
    29101 ttcttgtgct tgagcgggaa cttcttttcc ttctagataa tcatcaattt cattatatgt
    29161 gacacctagt gcgacttcat ctgcaatcat tggtttccca tcttcaagat ctgcagtcgg
    29221 aatttttgtg tataattttt ccggtgcatt caatgcttga agcaattgtt tcccttgtcg
    29281 tttgtccaaa cggaataatg gcaaaatgtc ggctccacca tcaccaaatt tcgtgaagaa
    29341 tccagtaatg ttttctgcag catgatctgt ccctaatacg gctcctgctc tttctccagc
    29401 tacggcatat tgcgtaatca tacgttgacg tgctttgata tttcctttgt taaaatcgct
    29461 gattcccaca cctgcttcgc ttaatacttg tacttgtgca tcaacagctg gtttgatatt
    29521 tactcgcaga ctaacatcgg gctggataaa gtcaagagca gcttttgcat cttcttcatc
    29581 tgcttgttca ccataaggaa gacgaacagc gataaattga tagttttcat cttttgtttc
    29641 ttcacgcatt tcttccatcg ttagttgcgc caaacggcct gctaaagtag aatcttggcc
    29701 gccgctgata cctagtacaa aagttttaag aaacggatat tttttcaaat atgctttcat
    29761 aaagtcaata cttttacgta tttcttcttt tggatcaatt gttggtttga cacctaattc
    29821 attgataatt tctgtctgca ggctcattta ttctcctcct atgcttctgt atgaagttct
    29881 gctacgcttt ttttcattcg ttccatgata gccattttat ggttccagca ttcagtagac
    29941 agatcgactg ggtatttttg cggattcaag tctcgtttat actcttccca tagtgaatct
    30001 agattttctt ttgtatattc tttgatttcg tttagtgcag gtaattcgta aactcttttt
    30061 ccttcgataa agatatcttg taaaactggg cgagctgtaa agtctcgaac agttttattg
    30121 ataaacgtat gcactggatg gaacatgaag atagcttctt cttctcgagg gtcttcatcc
    30181 cataatgtca cgtagtctcc ttcagatttc ccatcaaaat ttcgagtgat gcgccacact
    30241 tgttttttcc ctggagtagt tactttttct gcattgcttg ataacttgat cgtatccatc
    30301 atttttcctt catcatcttc gatcgatact agcttgaata ctgcaccaag ggctggctga
    30361 tcataggctg tgatcaattt tgtcccaaca ccccatacat caattttagc tttttgcatc
    30421 tttaaattca aaatcgttgc ttcatccaag tcattcgaag catagatttt tgcttccgta
    30481 aatccggctg catctaattg ttcccgaaca cgcttagata tataggccat atctccactg
    30541 tcgatgcgta cgccttggaa gttgattttg tcacctaatt ctttcgccac gcgaatcgca
    30601 cttggcacac ctgatttcaa cgtatcataa gtgtcgacta agaacacgca gtctttatgg
    30661 gttttagcgt aggccataaa tgcttcataa tcatttccat aagattggac taacgaatga
    30721 gcatgggtcc cgctagctgg tatcccaaat atcttcccag cacgtacatt gcttgttgca
    30781 tctgctccgc cgatatatgc cgctctagtt ccccagactg ctgcatccag ttcttgtgcc
    30841 cgtctagttc caaattccaa tagtggatct tctccgatga cagatttgat acgagctgct
    30901 tttgtcgcga tcaacgtttg gaaattgacc atattcaaca gtgctgtttc tactaattgg
    30961 cagtgcgcta aaggcccttc cacttggatt aatggttcat ttgcaaaaac tagttctcct
    31021 tcacgagcag aacgaactgt tgctttaaat tcaaaatttt gtaaatactc caaaaaacct
    31081 tcaggataga cttctaatcc acgcaagtaa gcaatatcgg aatcattgaa cgtcagattc
    31141 tctaaataat tgactaaccg ttccaatcct gcaaaaaccg cgtatccgtg gttaaaaggc
    31201 atttctcgaa agtaacattc aaaaacagca tgtaaatcag ctcgacctaa ttcccagtat
    31261 gtctgcatca tattgatttg atatagatcc gtatgcagcg tcaaactgtc gtctgggtaa
    31321 gtattattca tcttgtatta ctcctcttgg caagttttca tttcctaccc attataacaa
    31381 aaaaaattaa taggaaaaga aatcttccat tttttctgaa aaagcacatg ttttacggat
    31441 atttcttgct aaaaatgaac tccatctgct aaaactatcc tttcttattg gtatttaacc
    31501 taaacgagaa agaatactta ttttattcaa tgtatccgag acacgaagaa attagcgttt
    31561 tctatttttc ttacttgata aaataagtag attttcctac tacaatcgta gccgttaaga
    31621 taccgatgat tgaacaaata taaccaaatg tctctacaac ataatcaatg gcaaaagttt
    31681 ttgaagcaat aatacgtctt tccttttttg cttcttatcc ccaaagaaac ggatataact
    31741 tattatgtat tgaatttttt tggaaaggcg aattatgaca agatatacct tgcgttgaaa
    31801 aaactcgcgg aaaaaatatc acacgttttt aaaaagatac aaagtaagaa agcagctgtc
    31861 aatagaatgg aaacaaaaat ggcgagacat caatcagtct cgccttgttt tttattgtat
    31921 acattagata tggagcaggt taccataaag atgattatta gtcgttatta aatagaatcc
    31981 ttcgtatttt tttgttctat cactacaata tctttatttg gacgtttgaa ttgtattccg
    32041 gcacgttcta gctcctgttt cactcctaca tggactttga catcttctcg tgtcattttt
    32101 aaaacgtgat gaatcgcata gtcgatttct tgccttgtga tttttttctt cgtattgatc
    32161 atcacgactt gctttttatc atatgtgtct accaatagca gttgtgttcg atctaacgaa
    32221 aataatttgt aataattaat agccgtattc ccaaaaaaga attccactac tttaggataa
    32281 aatgtcttaa tatttaaatt actattcaca ggtgtttcga ttagcttcat ctcattcctc
    32341 ttttctatat agtcgattta gatccaatct taagttatgt taccatcttt cctagcatta
    32401 aggaatcggt tacaattgaa cctttaaaga caaaaggatt taccttttat cacttaatag
    32461 tataacataa tttcgtgaga aaaaaataca attttttctt gaccatctcg ttacgtaaag
    32521 gattatgctt acatttgtca ggaggaaaaa taatggagta cacaataaag aaaatgtcag
    32581 agatatcagg agtcagtccg agaaccttgc gcttttatga tgagattgga ctgctaaaac
    32641 cagctaggat caattcttca ggttatcgga tttatggcaa aaaagaagtc gatcgtctgc
    32701 aacacatctt attttatcga acaatggcat tcaagttgga tgatatccaa gaggtcttag
    32761 acaatccatc ttttgaccac cagaaagctt taatcaagca tcagcaaatg ttgctggaaa
    32821 aacgggcaca aatcgatacc ctcttgacaa ctgtccaaca gacacttgat atgtacgaag
    32881 gaggaagaaa aatgagtgac aaagaaaaat ttgaagggtt taaacaacaa aagttgaaag
    32941 aaaatgaaga atcctatgga caagagattc gacaaaaata cggaaaaaaa aaggttacag
    33001 catccaatga aaaatggatg aatatggata aagaaacgta tgaagaaatg caaactgttg
    33061 aaaagcagat gttatttgat ctcactcttt acttaaaaga accagaagat gaaagcttag
    33121 cagaccgtat cttccaagct cataagaagt ggttctctta cagctggcct gaatatcagc
    33181 caaaagcgca taaaggacta ggaatgatgt acgaagccga tgaacggttc actgcatatt
    33241 atgacgagcg aagtggtcat ggtgcagcaa aagctttaaa tgaaattatc caaaaaaagg
    33301 cgtaatcttt tacatgatcc aacaaaaaag tacacgtaaa atgacctaat aacaaaacag
    33361 cagacaccca agttagattt ttatgctaac ttttggtgtc tgctccattc tttcacaagt
    33421 tttttcatcc tactttaaat atattcatcg ttgaataaac gtataaggta ttttcacttt
    33481 atcctttttt tctgtaagaa acaattgaaa tgccatttct ccgcaagctt ccagatggtg
    33541 gtcgatggtt gggaaaccaa gaagctcgct gatcagcaaa ttatcgcgtc caatcaccac
    33601 tggtgtctta tcttgcagat agctttgcaa gatgcctgct gcaaccatat ccgaatttgt
    33661 aaagacacca tcaactccaa gctctttaaa aaagaagcct gcttgttttc ctttctctgc
    33721 atctatacaa tcccaaaaaa caagtgattc atcaaaagat ggaaaaagtt gatgacatag
    33781 ctgcaaagtg atttttgagt tataacttag cctgccactt cgccccaacg tgatgcccaa
    33841 ttgctttata ccttgctgct tcaaataagt aagaccttct gtaattgatt gttctcgatc
    33901 aataaagaca cagcttgcct gttttccctt gatttcttca caaaaaacta gaggtccata
    33961 tttttgatat gccaataaat catctagtgt attggcacga gacgtaatga tcaatccatc
    34021 gaaagcttta gctgcaaatt cttcaagata ccttcgctct ttttctttat gatagcccgt
    34081 cggtaaaagt gtcactttgt aatcataatc aaacgctgct tcaatgatcc cactgatcaa
    34141 ctgatcaaaa tacggatgat tggtataagg cagaatcact ccaatgcttt tcgtttttcc
    34201 ataacttaac tgtctggcat ttgcattagg gatataatcg acttctttca tgaccgcaag
    34261 tatttctttc cttttttcct catctacata tggatgtcca ttgattacac gtgaaatagt
    34321 agaaactgaa taacctgtga gctttgcgat atctcgaatg tttgccactg ctgcttcgcc
    34381 acctatacaa aaagattttc ttgtaaatag tctaccacag ctggaccgca ttcaaaaaac
    34441 tgatacattt ttccttcatg cgaaaaactg atccgctgcc cgccccaata tatatctttt
    34501 gtcaaatttt cgatttcatt cattggtatt tcttttacta tattcctatt caacccttga
    34561 aaactgtaca acgttaatac ggatcccttg aactcgacaa acgcataaaa ataattgttc
    34621 gttgtgccat ctgttatctc tacataagta ttcattgcaa gccctccttt tgatactttg
    34681 agtatagtgt atgaaacgcg tctcatagca aggagtttgt tttgccaaag aaaagtttta
    34741 ttcctctttc attattacca aagtctctta ttttaaattg aatacattat aatgatactg
    34801 taaatatatc tttattatta gtgaatg
//
LOCUS       DAFLWC010000019        34771 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.019, whole genome shotgun sequence.
ACCESSION   DAFLWC010000019 DAFLWC010000000
VERSION     DAFLWC010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.019"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(227..1114)
                     /locus_tag="L1V17_000892"
     CDS             complement(227..1114)
                     /locus_tag="L1V17_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1235676.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(1111..1980)
                     /locus_tag="L1V17_000893"
     CDS             complement(1111..1980)
                     /locus_tag="L1V17_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1235677.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(2117..3403)
                     /locus_tag="L1V17_000894"
     CDS             complement(2117..3403)
                     /locus_tag="L1V17_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1235678.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            3676..4254
                     /locus_tag="L1V17_000895"
     CDS             3676..4254
                     /locus_tag="L1V17_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBN1235679.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            4254..5183
                     /locus_tag="L1V17_000896"
     CDS             4254..5183
                     /locus_tag="L1V17_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1235680.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            5180..6916
                     /locus_tag="L1V17_000897"
     CDS             5180..6916
                     /locus_tag="L1V17_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBN1235681.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(6979..7815)
                     /gene="pheA"
                     /locus_tag="L1V17_000898"
     CDS             complement(6979..7815)
                     /gene="pheA"
                     /locus_tag="L1V17_000898"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBN1235682.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(7812..8321)
                     /locus_tag="L1V17_000899"
     CDS             complement(7812..8321)
                     /locus_tag="L1V17_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBN1235683.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(8314..9609)
                     /gene="aroA"
                     /locus_tag="L1V17_000900"
     CDS             complement(8314..9609)
                     /gene="aroA"
                     /locus_tag="L1V17_000900"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBN1235684.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(9622..10713)
                     /locus_tag="L1V17_000901"
     CDS             complement(9622..10713)
                     /locus_tag="L1V17_000901"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBN1235685.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(10730..11896)
                     /gene="aroC"
                     /locus_tag="L1V17_000902"
     CDS             complement(10730..11896)
                     /gene="aroC"
                     /locus_tag="L1V17_000902"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBN1235686.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(11898..12962)
                     /gene="aroB"
                     /locus_tag="L1V17_000903"
     CDS             complement(11898..12962)
                     /gene="aroB"
                     /locus_tag="L1V17_000903"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBN1235687.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(12995..14017)
                     /gene="aroF"
                     /locus_tag="L1V17_000904"
     CDS             complement(12995..14017)
                     /gene="aroF"
                     /locus_tag="L1V17_000904"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBN1235688.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(14676..15650)
                     /locus_tag="L1V17_000905"
     CDS             complement(14676..15650)
                     /locus_tag="L1V17_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HBN1235689.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(15631..17514)
                     /locus_tag="L1V17_000906"
     CDS             complement(15631..17514)
                     /locus_tag="L1V17_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HBN1235690.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(17532..19757)
                     /locus_tag="L1V17_000907"
     CDS             complement(17532..19757)
                     /locus_tag="L1V17_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBN1235691.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            19872..20906
                     /locus_tag="L1V17_000908"
     CDS             19872..20906
                     /locus_tag="L1V17_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1235692.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(20973..21986)
                     /locus_tag="L1V17_000909"
     CDS             complement(20973..21986)
                     /locus_tag="L1V17_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1235693.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(22064..22252)
                     /locus_tag="L1V17_000910"
     CDS             complement(22064..22252)
                     /locus_tag="L1V17_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HBN1235694.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(22692..22820)
                     /locus_tag="L1V17_000911"
     CDS             complement(22692..22820)
                     /locus_tag="L1V17_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBN1235695.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(22823..24196)
                     /gene="rlmD"
                     /locus_tag="L1V17_000912"
     CDS             complement(22823..24196)
                     /gene="rlmD"
                     /locus_tag="L1V17_000912"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBN1235696.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(24307..25362)
                     /locus_tag="L1V17_000913"
     CDS             complement(24307..25362)
                     /locus_tag="L1V17_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBN1235697.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(25372..26802)
                     /gene="gatB"
                     /locus_tag="L1V17_000914"
     CDS             complement(25372..26802)
                     /gene="gatB"
                     /locus_tag="L1V17_000914"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HBN1235698.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(26799..28271)
                     /gene="gatA"
                     /locus_tag="L1V17_000915"
     CDS             complement(26799..28271)
                     /gene="gatA"
                     /locus_tag="L1V17_000915"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HBN1235699.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(28271..28576)
                     /gene="gatC"
                     /locus_tag="L1V17_000916"
     CDS             complement(28271..28576)
                     /gene="gatC"
                     /locus_tag="L1V17_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HBN1235700.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(28682..30718)
                     /gene="ligA"
                     /locus_tag="L1V17_000917"
     CDS             complement(28682..30718)
                     /gene="ligA"
                     /locus_tag="L1V17_000917"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBN1235701.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(30735..32969)
                     /gene="pcrA"
                     /locus_tag="L1V17_000918"
     CDS             complement(30735..32969)
                     /gene="pcrA"
                     /locus_tag="L1V17_000918"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HBN1235702.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            33124..34683
                     /locus_tag="L1V17_000919"
     CDS             33124..34683
                     /locus_tag="L1V17_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HBN1235703.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
BASE COUNT         9518 a         7494 c         6336 g        11423 t
ORIGIN      
        1 gacaatcagg acagtcatcg gcaatatagc agcaatcact tctttaaaat tttttagcat
       61 gtatcctcct cctttactct ttaagtttac cttaaaatga aagagttttc gagcacaaac
      121 ttaaaacgtt atcatttaat ttttctcaac ataaaataac acacgtccca aaagtatctt
      181 tttacttgga aaaatgactt tgaaggaacg cgcttattgt gtttttttat tttacagagc
      241 cgatcattcc ttgaacgaat tgcttttgca aaacaaaaaa tacgatggca gttggtaaag
      301 tagcgatgac taatccagcc atgatcattc catagtctgg tgtataggaa gcacccatag
      361 cagataaaac aagcggaacc gtccgtttat caggagattg caaagctact aagggccata
      421 aataattgtt ccagctactc atgaatgtga tgattgcagc cgcggcatag gtatttttag
      481 ccgtcggcat atacactcta aaaaaaatac ttagttcttt tagaccgtct aatcgagcgg
      541 cttctactag atcttttgga aaagatttaa cattttgtcg aaagaagaag atcaaaaaag
      601 cagtgctaac agatggcagg atgacaacca agaaactgtt gattcccaaa accgttccgt
      661 tcaattgtga aaacattcga tataaaggga tcatcaatgc cgcaaaagga accatcatcg
      721 atagcagtag aatattgaaa attaggtctt ttcgtttact ttgataaatc tcaaatccat
      781 atcctgccat tgacgaaatc agcaatgcaa acacagtggt caccaaagcg atcatcgctg
      841 aattccaaag ggaacgagta aaattcagct cattggaaaa caaattttga aaattgatga
      901 tcaagttact gccaatcttt atttttcccg atgtgatatc cacgggtgta ttcgtcattc
      961 ccaaaaccat ccagacaaaa gggaaaatgg aaataaatga taggatgctt aatgctgtat
     1021 actttaatac tgacccaatt gtcgaacgaa gttctaatgc ttgttttttg acgttggggc
     1081 gttcgattgt ttctttttct accatatttt tcatcgactt tctcctccta ctttcgtttg
     1141 gattatcgac aatatcacaa taaaggaaac aataacaaag gaaactgctg ccgcatatcc
     1201 aaaattaggc gtgaatttat aactcaaatt atagatgtat tgagataggg tggtcgttgc
     1261 atttgctggt cccccgccag taatattttg tacttcatca aaaagctgca atgtcccgat
     1321 cgtcgaagta atggaagtaa acaaaatgat tggttttaaa tttgggatcg tcactttgat
     1381 aaactgctgc catttagaag caccgtcaat agatgctgct tcataaatct ccgaatcaat
     1441 attttgcatg cctgaaagga aaaaaatcat attgtatcca gtccaacgcc aagtgatcga
     1501 aagaatgatc agaactctcg cccaaattgg atgagtcaac cagccaatcg gtgtgtcaat
     1561 cataccaatg cccaacaaca agttgtttac aaggccagat tgagaaaata gacttttcat
     1621 gatcagagaa taactgacca tcgaagtgat acatggaaga aagatagcgg ttcgaaacaa
     1681 ccctttatat ttcaactttt tatcatttaa aaggttggaa ataaaaagtg ctagaaacaa
     1741 catgatcggt acttgtacaa gtaaatacag gaatgtatta aaaaaagctt ttttaaaagt
     1801 tgcatctgtc aacatccgct gataattacc taacccgtta aatgtcatat tgacaggggg
     1861 accactttga aaagacgtga tcaaagccaa aaccatcgga ataaaaacca tgattgatat
     1921 caaaatgact ggcaagatta aaaaagcatg cccgtttttg aataaatctt tctgcttcat
     1981 tcttttccct ccaattctat cattgattat ctacatgaaa agacaagaaa gacaatatct
     2041 gtaaggcaga cgtgatcttt tttgtctttt cgtttgtctg atgaaaaagc gaagaaattc
     2101 acttttttac caccgatcaa ttagccaatt gtgcttctac ttgtttttgt gtatctgcta
     2161 gtaccttgtc tgtctcttct ccattgatga ttcgatgaag agcttcagct acgactgctt
     2221 caattgcata ggtctcatgt ccgtaattca cttctggtat ttcagatgtc catgttgaaa
     2281 aatcgtcaaa gatcttttga ccactgtaaa attcagaagc ttcttgataa gcttcttgtt
     2341 cattcgcgct aagcatcgta gatactagtc cgatttcttt cgcaagagtg cccatcagtt
     2401 cttcattcga agcaaacgtt gcttctagga aatctttcgc tgaatcttct ccagctactc
     2461 ctttgatcac ataccagcca gcgccgccaa ggttagaagc ttgcgctttt tgcagatttt
     2521 ctggaagtgc aggtattggt gcaatcttcc attttccaga ttggttttct gctccttgga
     2581 tcgttgaaga ataccaagcg ccagttgggc tagaagctac tgctcctgat tgtatcgcag
     2641 ttactccagc attccagtca gaggtttgtt cgactagatc ttctttcaaa agagtggcaa
     2701 acaattcaag accatacttt aaagatgcat tgtcttggat cgtgactgtc tccccatctt
     2761 cagatgtata ccattctcct gcctgttgca taatcatcct tactcgacca aggtcagaag
     2821 gattgacttc agcgattttc tttcccgtct tttctttgac atctcgcgct acttgaatat
     2881 actcgtccca cttcagattc tccatatcct cttctgtata acctgcttct gccatcagat
     2941 ccgtacgata gaagtttgct gttacgcccg aatcgaaagg aacaccgtat attttatctc
     3001 ctactttgtt taccgcaaat ttatacggtg caaaatgatc ttcctttaca atagcagaca
     3061 aattagcgaa tgcatctgga taagaagtca aatagccttg tatcctataa tcttcaatca
     3121 agacgatatt gggcaatcct tctgtattcc cgctcgctaa agcggtgttc agtttctgaa
     3181 cgatatcatc ctgagacatc gtaacaactt ctatctctgt ttcttcgttc tcataaactt
     3241 tttttgcttc attcactgct ttgatattga atgtctcatc ccacgcccag acagtgactt
     3301 tttcttcttt gtctgctgta ctactagcac ttccgcatcc tgttaagaaa cctgatgctg
     3361 ccgctaaaca aacgactcca gcaattaact ttctgatgtt catttttatc cgctcctttt
     3421 ccatccatta gttgtttacg tttgctacat tcatcatacc aaaatttgaa aacggtttct
     3481 ttattattca gatacttcaa aaatttctcc taaaataata aaaaaataca aatcaactat
     3541 gacaaaagga ataatcttag catctagacc aaagatcgaa atggtgaggt ttctttaaaa
     3601 taaaaatatc cttgcatttt ctcctagaaa taagtatttt taaattacaa gactattctt
     3661 aaggcgggta aaaaaatgcc aatacgcgta attcttatcg atgatgaaca gacgatttta
     3721 gatggaatga aacagttgat caattggtct gagcacgggt ttcaattaat agggactttt
     3781 tccagtccgc tgaaagcgct tgatttttct ttggtacatg caatcgatat cgtggtcaca
     3841 gatgtaatga tgcctgaatt aaatggaatc gaattatcgc ggctattaaa acagcaacaa
     3901 cctgaaacac agatccttat cctctctagc tatgatgaat ttgatatggt taaagattct
     3961 tttaaagaag gcgtcgctga ttatctttta aagcctcgat tgagtcctga tttttttcta
     4021 aattccttaa ctgccgtttc acaaaaaatc aaaaaaaagc ccaacaaaag cccaatcacc
     4081 aatcgttatg agcagatctg cgagaatctt tcacagcaga ttgctggaca aactcgtcca
     4141 ttgcttgacc ctcttctttt tgaacacacc ttgtttttct gttatatacc gaaaaacggc
     4201 cattcagttc aaaacaaggc tctaaacaaa aacagtcgat cacccattca ttgatggata
     4261 gcgacgattc gtttactatt tatcctgttt ctaccttttc ggaagaatcc ggctatgtaa
     4321 tcaatactga ttccaaagat acacttagga agtttgttca aaagtttcgt caagaagttt
     4381 ttccaggtga tttttttgtt gtttctgatt cttttgcaat ccaagatatc aatgaaatat
     4441 tccaagagat cagaaattgc accaaaggac aacgtttcta tcataaggga aagaaccttg
     4501 cttatcagca tgaacttctt ccgttattaa ccaaccacga gcagcaagca agtagttatt
     4561 taacaaaaat cgttcataaa gactacgctt tagctgtcaa agaacttgag aatttcttca
     4621 cgacgatatt ggaacagcct attgatccag cttatttgaa acatgaggca atcaatcgtt
     4681 tctatgcatt actcaacgct ttggctgacg agcatgttgg gaatgaagaa ctttctttgc
     4741 tcaagatcgc ccttccttct ttattagccg atgctgagta tttcgaagat ttttctattc
     4801 ttgtcaaaga aacacttgag aaactcaccc acttttctgc aaatgcaaaa aaagacaatt
     4861 tcgatatctt gactttgatc tacgagttcg tccaggaaaa ttatgagaaa gaaatcaatt
     4921 tacaactttt atccgaaaaa tatcattttt catatagcta tctctcagcc atctttactg
     4981 aaaaatttgg tatcaacttt tcaaaatatc taaaaaaagt ccgtatcagt aaagccaagc
     5041 tctttttgac ggaaacacgg cttactttga cggaaatctg tgagaaagtc ggctataccg
     5101 aactgggtta tttctccaga gtttttaaag aagagacagg aatgacacct tctcaatacc
     5161 gtaaaggaac ttttgtaaaa tgagaaaaaa aatcaaagag catgaactct ttgccaaact
     5221 tctgttcatt ttgttcatcg gtctttttct gcaagccatc gtcatttctt tgtttattta
     5281 tcatcgatca agggatgcct atatccagct gttcaatcaa tcgaatgatg tggtactaaa
     5341 aaagattcaa tctgaatttg aaagtttgaa tgatacaatc gagaatacat tagccgcttt
     5401 tgattctaat ccagctgtca aaagctattt ttccaatgat ccagcccaac atatggaaca
     5461 gcttcagcaa ctaagaacaa tccaaaaaat gaatgactct ctttcaaaaa tccatccaat
     5521 gatcgattac gatgtattga tctttggaga aaatggaaga acttttgtcg gaaacgacat
     5581 gctcactgcc gtatctgccg attctttttt tcaatctgcg attgctcaga gagtgaatga
     5641 acgtgctgct gatacacaaa tgctttttgc acaccacgga ttgactcttc gcgataagaa
     5701 agcacccagc gtcttctttg tcaaaaaact gaaaaataca ttgaatcacg tttacggata
     5761 tgctgtttta tcgatctcat ccaagcaact agcgaatctt tttcaatctg tagtaaatcc
     5821 tgagatatcg aagatctcct tcatgaacga agaacagacg atcatcgcat caaatgaaga
     5881 aaatacaatt gggagccgat caatgatttt caaaaaacta acagtaggtg aaacaacgat
     5941 ttcaaatgga cagcagttga cccgtcttcc tctgtaccgc caggattgta cattactcag
     6001 tcaagtcgat cttcattctt tatctaacca aatgggcgtg atttttccga ttattttgta
     6061 taatatcgtg acacttgctt ttgctggctc attggtattt atgtatttgg atcgacacac
     6121 aaaatcgatc taccgcttga ttgattcgct aaaacggcta gaggaagatg gcttaaaagc
     6181 tactgttcct gtacaaggaa gccatgaagt ccaattgcta gggaatacga tcaatcaatt
     6241 gctaagtaat gctcagcatc attatgaaca gacgatccaa gacgaaaaga agaaacgttc
     6301 gcttgaaatc caaactatgc aagcacagat acagccccat tttatttata atacgctgac
     6361 tagcttgaaa tttttgattt ggcagaaaaa aacagatgaa gcagttcaag gaatcgacag
     6421 tttcattact ttactaagaa gtacgattgg gaaaaaagaa gaagtgattc cagtcaagga
     6481 agaaatcaaa agcgtacaaa gttacatcga tcttttgagt atgcgatatg gcgaaagaat
     6541 ctcggctaaa ataatgattc ctgatgaact gcagtcatta tctatgccga atatgatcct
     6601 tcaaccaatt atcgaaaacg cctatcttca tgcttttcac aataaaacgc aaggattcat
     6661 cacggtgtac ggcaaaacaa aaaatcagct tcttttattc gaagtgattg ataacggcga
     6721 tggcttcgat actgaaaata ccaaacaaaa aaatgatcat ttttcaggaa tcggcatcag
     6781 ccatgtagat gagcggatac gcctaatgta tggcgatgca tatggcttaa cgatccaatc
     6841 agtgattggg acaggaacga ctgtaacgat ttgtctaccg cttcttccta aaaatcaatc
     6901 agaatatcaa aaataaagaa tagccaagcg ctgatttttt tattttaagt taaataaatc
     6961 aatcagtatt cttgactttc atctacgcgt ctcttctact gtcagcactg gataacagcc
     7021 caatatttga ctttctcctc cgagcatctt gatttcttgg agcgcattct ctactaatgt
     7081 cattggacgg tccaacaaca aatcgatcac gaaaaaatat tctcccaagc tagttttcaa
     7141 tggtcgggat tcaatcttac ttaagttgat ttcccgccag ccaaaagctg ccagcatttt
     7201 atgaagcatc cctggccgat tagcaggtag tgtcaagatg acactcattt ttactggagc
     7261 tgactgctgg ctggtcatct ttcggtcacc gacgatccaa aaacgtgtct ggttcaactc
     7321 attatcttgg atattctcag ctaagatctc caatccaaca tgctgtgctg tttctaatga
     7381 agcaatcgct gctgcgtctt ctttcggatg ttctgctaca tacattgctg cagcagttgt
     7441 tgattctgtt gctactaaag gaacattagg ataatgcgtt tctaaaaact gttgtgattg
     7501 tgctagtgct tgtggatgtg aaaggatttt tgtaatcttt gttgctggat tgcctaaaag
     7561 ctgctgcttg ataggaagaa cgatttcact tttaacttcg acttctggat gtttggaaag
     7621 aagatcgatt gtgtgatgaa cagctccttc caatgaattc tctacaggaa cgacagccag
     7681 atcgacttgt ttgcgaaaca aagcgcgcaa acaaacaggg atggaagcat acgcagtcaa
     7741 ttgttctgta ggaaatagct gacaagccgc ctgataagtg aatgaacttt ctggccctag
     7801 atagctgacg ttcatatgct tttgatcctt tctataatgg tatcgatgat cttttctggt
     7861 gtttgattgg tcgtgttgat tcgatgtgtc gcactttctt cataccaaga aagtcgttgt
     7921 gccaataatg cttttatttc ttctcttgtt tttccaagag ctaaaggtcg aatagacgtt
     7981 tcatcttgtt ggatacgatc aactagacag tccgcttctg cctctaagta aagaacaatc
     8041 ggctgtgttt ttaaaaaacg ccgattttct gcactttgga caatccctcc accagtcgcg
     8101 ataattttgt cttcatttga cagctttctt aaaatatctg actccacttt tcgaaagctt
     8161 ttttcaccgt aatagtgaaa atattcggca atcgacaatt ggatatgttc ctcaatcttt
     8221 gtatctaaat ctacatactc tttttgtaaa cattgagcta accctttacc gattgttgtt
     8281 tttccagcgc ccatgaaacc aatcagcaaa atgctagcca tgagcttctc ctcctgacac
     8341 aagttctgct aaatcgtcaa aaaatgccgg ataagagatt gaaacagctt cagctccttc
     8401 tagttcgcaa ggtccatcag ctatcaaagc agctacttgc agcatcatac cgattcgatg
     8461 atcgcctctg ctggacactt ttgcgccatg cagaggtgtc ggcccatgga tgatcagacc
     8521 gtctgctgtc gcttttatct ttgctcccat tttctgtaat tcttctgcca ccgcatcaat
     8581 tctgttggtt tcttttactt ttaattcttc tgcgtctttg atgatcgtga ttccttctgc
     8641 ttgagtagcc actaaagcta gaatgggcaa ttcatcaatc agacgcggaa tgatttctcc
     8701 accaatcgtt gctttcttca aatgactcgt cttgacactt aaatcagccg attggttctg
     8761 ttcattgtga ttcgtctggg taatcgctgc gcccatctcc tccaacacat ctaagatacc
     8821 agttcttgtt ggattgaccc cgacattttt taacaacagt tggctttccg gaacaagaag
     8881 tcctgctgct agaaagaaag cagctgatga aatatcacct ggaacagtta tctgttgacc
     8941 agttaatttt tgcggtccgg tcactatgat cgttttatct tccactgtga tccttccgcc
     9001 aaattgacga atcatttctt ccgtatggtt acgggaacgt tctttttcaa cgattacgga
     9061 tgtgccttct gcttgtaatg ccgcaaacag caaagcagat ttgacttgcg cactggctac
     9121 aggcatattg tatcggatag gtgataaaga gcgggttcct gtcacagtga ttggtagata
     9181 ctggtcattt tcttctcctt gcaagtcagc gcccatctcg cgtaaaggtt ccatcactcg
     9241 ccccattgga cgtttagaca acgaagcatc cccgaacaga gtagtcgtaa aaggctgtcc
     9301 agccaaaata cccatcaata aacgtatggt cgtaccggag tttcccatgt caattgattc
     9361 ggttggttgg acaaatgagt ggctaccgcg accatgaatc ttgatcacct cttcctcttc
     9421 ttcgatctcg acacctaatt gttggaaggc atgtaaagta ctcagacaat cttctgcgcg
     9481 caaaaaattt tgtatagtcg tcgttccttc agcaattgct ccaaacatga tgctgcgatg
     9541 ggaaattgat ttatctgctg gtatcctaac agtccctctt aatccatgta tttgttgtaa
     9601 taattgcatt tatccagcct cctatttgat ccagcaatga taactggtat tagacataat
     9661 gattcttttt gcttgtaaca aatcctgttg gtttttaaaa ctgatttgca gtattcctaa
     9721 aatatcttcc ctggtctctt ggatcttcaa attaatcaaa gaaactcccg cttttccgat
     9781 cagtccagtt acttctgcaa taacgccagg ttcatctggc acatcgataa ataaatcaaa
     9841 aaaggcagga atcgcgcctt gcttatggac aggcaactgg tctcgacttt cttttgcccg
     9901 attgaaaaaa gaaaagattt ccgattggtt ctcagtcatg atccattctg ctatttgtgt
     9961 catttcttgt tgccaatctg ccaatcgttc caataatatc tgcttattgc tcaacaaaat
    10021 atctgtccac atgacaggat ctgaggaagc gatcctagtg atatctcgaa agcctcctgc
    10081 tgccagttgt ttggctcgcg gatactcttg attgaattgt tctgcctgat tgactaagcc
    10141 agctgccaga atatgtggaa aatgacttag cattcctgtt atacggtcat gttctcttgc
    10201 tgtaagagtt acatattttg ctttggttcc gcaaaatagt tcttgcagtt tttcaacatc
    10261 ttttttcgtc ttttccaaag gtgtaaagat gtaataggca ttttcaaata gtttagcatc
    10321 tgctgcctgt atacctgatt tatgagaacc agccattgga tgtccaccga caaaccgaag
    10381 atttttctgc tcagcggatg tcacgacttg ctgcttcgta ctgctgacat ccgtaatgat
    10441 gacgtgatca gacaagttga ttctttcaag gacatcaaga taagctaagg ttgtacggac
    10501 gggaacggct aataagataa cgtctgcttg ttctgcacct gtttcaaaat cacttgcaac
    10561 gtaatcaacg atctgctgtt ctactgcttg ctcacgggtt tttgactgac tatcccaacc
    10621 aactactatc agttctggat tggtctgacg aatacaaagt gccatagaag caccaatcag
    10681 tccaagcccc acgataaaaa catgttgtgc catcttattt gccccctttt tagtaatgtt
    10741 tcaagtagtc acggtactcc ttcactgcag ctttcaactc aacaagcgaa tcacttggga
    10801 attttgacaa tagctctgtc gctaccacag tggctacaac attttccgca acgacgctag
    10861 ctgcaggaac tgctgtacta tccgaacgtt ctacacttgc tttgtaaggt tcttttgtat
    10921 cgatatcaac actttgaagt ggcttgtaca atgtaggaat gggtttcatg accccgcgaa
    10981 tgacaagtgg ttcgccattg gtcattccgc cttcgaagcc gcctagatta ttggtacgtc
    11041 ggaaatagcc tctttcttct tcccatagga tctcatccat cacttctgag cctggtaatg
    11101 aaccagaagt gaatccgacc ccaaattcta cgcctttaaa ggcattgata ctaaccacag
    11161 cttgtgcgat tttggcatct agcttcgtgt cccattgtac gtagcttcct aatccagctg
    11221 gaacgcctcc aacgagcact tctacaattc ctccgatcgt atctccattt ttctttgtct
    11281 gatcgatcaa atcttttatt ctttgctcaa ctgctggatc aacaactcgt acttctgacg
    11341 cttcagaaat ttctttgatt tcttgaatcg agatatttcc aggtatttct gcttggattc
    11401 caccaagaca aatcacgtgt cctgctacga tgatgtcaag ttcttccaga attttcttgg
    11461 caattgcgcc gattgctaca cgcatggtcg tctctcttgc agaggaccgt tcaagcacat
    11521 tccgaagatc tcgatgatgg tatttcatac cgcctaccaa atccgcgtgt cctggacgcg
    11581 gacgtgcaac tcgccgcagt gattggtctt tttcaggcac ttctgctaca gacatgacag
    11641 ttgtccaatt tttccaatct ttattttcta ccactaaagt gacaggtgaa ccaattgttt
    11701 tgccgtgacg gatgccagac gtgatccgaa cacgatcttt ttcgatcttc atccttcctc
    11761 ctctgccgta accagcttgt ctgcgagcga gttcgtgatt gatttcttct tctgacagag
    11821 gtaatcctgc tggtagtcct tcaataatgg ctgttaattc tggtccatgg gattctcccg
    11881 cagtcatata acgcatctta cagtcctcct aagtaatctt tgaatgtctc tgtgggaaca
    11941 ggaacgattt ttgcttgccc aatcttttct agcaagatga tattcaattg gcttcctctt
    12001 gctttcttat catgggttat cgcgtggaat aattcatctg gatgacttag atcgtacgta
    12061 atcggcagat ggaatttttg aagtatcctt tctaaagcag ctgtcgatcc agttggagac
    12121 aagccgattt tttctgcatg agaagtgatg gctaccattc caatagctac tccttctcca
    12181 tgactgacta ccccatatcc tgctgtattt tcaattgcat ggccaattgt atgaccaaaa
    12241 tttaaaataa gtcgatttcc ttggtcaaag acatcttctt ccactacttt tcgtttgatt
    12301 tccaacgtag cagtaatgat tggaacagca tgttccagaa gatctttttc gtctttcagc
    12361 tcgttcagct gtttccaaag cgttgcatct gctatagctg ctgatttgat gatttcagcg
    12421 attccttctc gtaaacgacg taccggcaaa gtttttagaa cctcaggatc aatcaataca
    12481 ccagctggct ggctaaatgt tccgacaagg tttttcgctt tgtttgtatt gactgctgtc
    12541 ttcccgccaa tactagaatc tacttgtgca agtagcgtag tcggaatttg aacgaaatgg
    12601 atcccacgca tgaacgtcga ggccacgaat gctgctagat cacccaccat tcctccacca
    12661 agtgcaagta tcccatcgct gcgggtaaaa tcattatctg ctaaaaaatc gtataactca
    12721 gctgcttgtt ctaaagattt actggtctca cccgccggta cgattgaaag gactggttca
    12781 aaattagctt gtctcaattg gaacatgatt ttttctgcat atagtggagc aacgtttgta
    12841 tcagtgatca cagctacttt ttgaggtctc caaatcgttt gaagccatga tccagcctgt
    12901 tctagtgcgc ctttttcaat atgaatatcg tatttttggt tatcaacatg tacagtaagc
    12961 attcgtttca cttctttctt ttaaaaagct ggaattaatc gagtgtctga atcttttcca
    13021 ttgcttcttt catgatcgca acttctttca tcatgcgtga gtaagtcttt tcattcaacg
    13081 attggggacc gtctgaccaa gcatttgcag gatcaggatg gatctctacg atcatgccat
    13141 ctgctccgct tgccacaccc gcacgagcca ttggtggtac aagttcccaa attcctgtac
    13201 catgacttgg atcaacaatc acagggaaat gagttaattt tttcatcaat gggacagcac
    13261 ttaaatcaaa cgtattacgt gtcgctgttt cgtaagtccg aatcccacgt tcgataaaaa
    13321 tgacaggaga tttgtcttcg actgcaatgt attctgcagc attaagccat tcattgatcg
    13381 taccggaaat tccacgtttc aatccaacag gtttacctgt tttaccgaca gcagatagca
    13441 gtttaaaatt ttgcatatta cgtgcgccaa tctgtaggat atcgctgtac tcagccacca
    13501 tatcgatatg cccttcatcc atcacttcag taatcacttt cattccaaat tcatcagccg
    13561 cttgacggat gtatttcaat ccttcttctt ctaaaccttg gaaagcatat ggagaagtac
    13621 gtggtttgaa ggcaccacct cgcagaattt ttgcgccccc ggctttggcc attcgcgcac
    13681 attctctgat ttggtctaat ccttcgatag aacaaggacc agccatcgtc acgaaactgc
    13741 cgtcaccaat ttttactccg tctacatcca cgactgtatt gccaggatgg aattctcgag
    13801 aagtcaattt gtatgtgttt aaaatacgca cagcattttc tactccttca tagcgtgtaa
    13861 atgctccttc ttgtaaactt cgcgtatcac cttttagtcc aatcactact cgttctgttc
    13921 cttgatcgat tgagactttg aatccttctt tttcgatatg atcgacgact ttttttattt
    13981 gttcttccgt tgcttctttt ttcataatta ctatcattgt ttttcccgct ttcttttgtt
    14041 tacttatcta tcttggctga ttttctctac tttttcaagg tggttttaca ttaattccta
    14101 ctaaatgacc gtgtcctgtt gttctcattt tcgctccttc tttcctactt atgacccaga
    14161 taatcaacaa aaaaagatgt ccctgtagga aattgcctct acagtgaaca tcttcaacga
    14221 gccttaaaaa gcgctgcaaa aatataaaat agccactata gatgaatttc tctacgtggc
    14281 tgtaagtcgt gtttaaaaat ctttagccat catagataca aacctggttt gtttgtaccc
    14341 acgaagtcat gaatacaaac ctatctaaaa tagctaaagt aatacgtatt cagttttgta
    14401 agttttctag atttcataaa aaatcgctcc aaactgatgt aagaattgta cctagtatag
    14461 acataaaaaa atcgactgtc aatcattttt atgaaacttt ttttaatttt ctgatagtta
    14521 actttgtttt tcagaaaaat aacaattggt tttattgaag aaaatagtca tgaacaaaag
    14581 tatctgagaa cttttttact ctcttgttca tgacatatag aataaagcag ctttgtcttg
    14641 taaactccgt ttttcaaata ataatctaaa gattgctact gaataataaa gccgatttca
    14701 tggtcctctt cgctgctgat tcggtaaggt gactcaacat ccgctcccca gctattgata
    14761 cccccgactc ctcttacttt tgcaaaaatc gtaagaaccg ttcgtctttc tggcggtagt
    14821 tcttctatat gtgttgcctg ttccagttct tctgctttga atggtaaagc ggaaaaagca
    14881 aatggcgtat cctgctgttc aaatcgcaac gaaaaatctt cttgatcttt atccgtatta
    14941 tccaacgttt gatttcttgt tagttctacc catttcgttt ccatatgcat gccgcattct
    15001 tggggaacaa ggtatgggga aacggggagt cctgccactt tataaatacc ttcgacacca
    15061 ccagccatcc gatccggata tgtttcccct gataggcctt catactcaaa aaattttgct
    15121 ttcgttggca taatgaacct taaacccaat gcgggtaatt ccggtaatcc tttttgtcca
    15181 taataatgca tattgacaag cattttaccc tctccagcga tttggtagga aattgtcact
    15241 tgggtttttg gtactgtgtt gatttccagt gtaaaaatga tttcaaccgt ttcagcgtat
    15301 tcattacttg aatattgatt atttactgga gcaatcggca aatcgatctt tttattgtcc
    15361 accagtactt ctatttcttt gacttttgga tacaatccgg ctcctaacca cataccggat
    15421 ttaaatccaa atccgctacc tctgtcatta tcggtcgttg ctcgccaaaa aactggaagt
    15481 gtttcccggt atagccattc ttttccgttt ttattgagcg attccagtcc gcctcttgta
    15541 taagaaaaaa tataatgcgt attccccgat ttgacaccta atgtacagtc gccgaagacg
    15601 attgcaactt tttccgtatc catatgactt ttatttactg tatttttcat aataatatct
    15661 tacctcctgc atggcgggtt tttcttgtcc atctgcaaaa acgatcccat tccctgagaa
    15721 ttcatagtca cttggtttat cgtcaaagtc accgccatag cgcatcactt ctctgcctgt
    15781 gattggatca gtcacttgga tcgcctgatc tttaaaatcc catatatagc ctccttggta
    15841 catttcataa cgatcaagca acgtcatgta agaatccatt ccacctaacg aattccccat
    15901 gtcatgcata tattcacata agatgaacgg tttttccgct ttattttcaa ggtagtcaat
    15961 gatctcttct ggtggcgcat acatgcagct ttttacatct gaaatcgaat cttcgaatgc
    16021 tggatttgga aaattccctt cataatggac aagtcgatcg gggtctactt ttttgaagta
    16081 atcgttcatt tgtcgaatgt tttcttccgc ataagattca tttccaagag accaaaaaag
    16141 aatacttgga tggtttttta atgtttcgaa attcgttttt gctcgatcaa gaacagccgc
    16201 ctgccactga ggtactgcac ctggtacgtt gtaagaaggc tcaaatgcgc ccattttttg
    16261 ccatgagcca tgggattcga ggttcgtttc cgccatcaca tggattcctg cttggtcgca
    16321 taaataatac caagtgatct ggttggggta atgagatgtc cgtacgccgt tgatctttgc
    16381 attttttatg atagccaaat ctttttccat atcttctata gtgatggcgc gtcctttttt
    16441 cggatgccac tcatgtcgat ttaccccgtt gataatcatc cgttttccat tgaagtagat
    16501 gattttatct ttgatttcga ttttacgaaa accgaaggaa tagtcaatat actccgttac
    16561 tcttttttct tcgtctatcg tctccaattc aagcttatat aaattgggct gaaaatgccc
    16621 ccacagtgcc acattttcaa atccatcgat gcgaatcgtc atttgctctt ttaacggata
    16681 ttgctgttga tagatttcct tcccatcagg atctagtatc gctacattca gctgactgtt
    16741 tttggctact tgctcaaaag acaaatctac ttcaagtttg ccattttgac atttgtcatc
    16801 taagcgaggt ttgatccaaa gatcttctaa atggttttgt cctcgagcaa ctaagaagac
    16861 atctctgaag atcccaaaaa atcggaaaaa gtcctgatct tccaagaatg cagctgtact
    16921 tcttttgtaa acctccacag ctagaatatt ttcttcttcc aaataaggtg ttaaatcaaa
    16981 ttcagacgga gtgaacgaat cttcggcata cccgataaaa tgaccattca accaaataaa
    17041 cattgcttgt tctacaccag caaaatgaat cgagatttgt tttcccttta gaccttcttc
    17101 taatcgaaaa gtcgtcaaat acgaaccaac cggattgtct ttagcagctg aaaagatccc
    17161 ttccgcctct ttctcagggc ttgtcgtgaa agggggacgg cgaaatacat gtccctccca
    17221 cggatacatc gtattgatgt aatggatctt gtcataattt gctaattcaa tatgactagg
    17281 aacagtgatt tcatcaaaag aacaggcatc aaaatctttt ttataaaatg tttttggtcg
    17341 taccgaagga tttggcgaat aacaaaaacg ccatgatcca tttaaagact gtttaaggga
    17401 ggatgtggtt tctacttctt cccttgttgc ataacaaaca tgatcgctat gtgcatttga
    17461 ttggttcact ctaaaaactt gtggatcatc taaccatttt atatttgctt tcatactttt
    17521 ttccttctct ctcataactt tttgaaatga agcagttctg tttggaaatc accttgaaaa
    17581 tcggggaagt aaagtccaac tgtcatcaat tcggcccccg aaaatatccg cttcgaggtc
    17641 tgttcctgat aaagtgcctc atcatctaac cccatcagat atacttcatg gaacgctggt
    17701 tgagctgaag ctagtatcct ccctaaaaac acaatagctt catcttgttt aggagacaca
    17761 aacatccatg cggcaatatt ttcttcaaaa ggactcgcca aacgataata atggccatac
    17821 tggatcaccg gacgaatcgt ttgataggat ataatttggt cttttacttg ctttttttct
    17881 tcaggagaca gctttgtcaa atccagttca taaccaaaaa cagcgctcat agctgtttct
    17941 cctcttgttt tcaacgaagt agatctgtcg gtctgatgat ttggtacagc tgatacatga
    18001 gctgtgatgg acgaaatcgg ataagcaagg cttgttccat attggatttt catacgctcc
    18061 actgcatccg tgttatcact tgtccatgac tgcggcatat aataaataaa cccggcatca
    18121 aaccgtccac ctccaccaga acagccttcc cataagattt ccggataatc agttgtcaaa
    18181 tgttcaagta gttcataaag cccgagcata taacgatgcg ctacttctcc ttgtctctgt
    18241 gggtcaaggg taatcgaata gacatctgaa agcgaacggt tcatatccca tttgatgtag
    18301 tcaagaggaa tcgtatctaa aatctttctc atttgtttct caatcgtctg ccgaacatct
    18361 aaccttgtaa aatccagtac atgttgtgat ctggaagcag aaggcattct acctggctcc
    18421 tgcataagaa aatcaggatg tgttcgatac agttcagaat caaccgagat catttcaggt
    18481 tcaaaccata aaccaaattt caatcctttg ctatgagcat aatctgctat ttcacgtaat
    18541 ccatttgtca acttgccttc atactcgaac cagtctccta atgaagaatt gtccgcatct
    18601 ctttttccaa accagccatc atctaatacg aacatttcga tgcctagctc ctttgcttca
    18661 tcaatgatcg ccttgatttt ttcactattg aagtcaaagt aagtggcttc ccagttattg
    18721 accagaatcg gccgttcagc aaattgatga cgacctcttg cgattctttc acgtagcaac
    18781 tcatggtgga tctgactcat tttgttcaat ccctgacttg agtaagaaag gatcatttca
    18841 ggtgtttgaa aagactggcc tgcattcaat tcccacgaaa aacgatggct gttgatccca
    18901 ccgacgactc tcaattgatt gatctgatct ttttcaagtt cgaaagaatg gttgccggaa
    18961 taaacaaatt gaagtccgat cgcttctcca gtattttctg tcgtatgatg atgaactaaa
    19021 gcaataaagt tattcatatg gtgactgctc gttcctcgac ggctttcaaa tacttttgtt
    19081 ccagataaaa cagattgccg tgaaatctgt ctttcattga catgtgctcc tggcaaagca
    19141 atgacttcat caaatcgcct agtatgggca aagtctagct ggaaactagc cgctttttct
    19201 agtttgattg tttctccggt ttcatttctt atctttacag atcgtgtgat cactgctcta
    19261 tcagtaaata tggtatagaa caaatcgaaa taaatcgctg tttctctatc cttaagtgaa
    19321 atcaccaacg tttgtgcctc tgacttgtcc atcacataag tttgaggcaa gccttcgatc
    19381 tctggcttcc catctgtaat ataatggctg tcatatctca gatccagtaa gtctgatcca
    19441 ttcttgcgct gaatgatcga tgcgggcgtt cgaaagtcca tgctgccatg agaagagtat
    19501 tcttgcggta gtgtatcttt cgacagagac cggtcaggat ttaagggaac atttcctgaa
    19561 aatccacgat ctcttcgggg ataattttta ttgtctttgt actgcttgac tggtttgcca
    19621 aaataaatat gcgccaatac attgctttct tctatcttta tcagataaga aagaaatgta
    19681 tttcgtaaat ggaagactcg gctcttttca tcaaataaga tgaaattttt atctgttttt
    19741 ctatgcgtaa tatccatcat ttcactccca acaaaacgga aaccgtttac ttttttttat
    19801 aattcctgta tactgtttac taaacaattt tgtcaataaa aattttttat ttttttgagg
    19861 agtgtgtaaa aatggttgga attagagatg tcgcacgaaa ggcaaatgtc tctcctgcta
    19921 cagtttcccg tgtgttgaat aacgatcaga cgatccatgt ggctcagact actcggcaac
    19981 ggatagtaga ggcagctgct gcgttggatt atgacatcag tactcgtaaa tatatcaaaa
    20041 agagaatgcc ttcgattggt gtgatctcta cgatcggcaa agcgagcgaa gaacaggata
    20101 tctattacaa acatttgcga gtagggatgg aagaagaagc tcgacgtctg catttaggga
    20161 tgaatcgaat ctataatcta tctgataatc ctaaacaatg ggaagatcta gatcagttag
    20221 gtgcggtgat cgttgttggg actgttacga aagaatcgat taccgccttg ttaaaacaaa
    20281 acatgcaaat agtcgtcgtg gataaccctg acatccagca agaggtcgat atggtgtatg
    20341 cagatcttga acggatgact aaaaccgtac tggaattgtt cttagaaaat ggtcataaaa
    20401 gaatagccta tatcggggga tataaagtcg atatggatga attcggtggg aagcagattt
    20461 ctataaatga aaagaggatg cgtgcctatc agcattttat gatcgatcat cacttagaaa
    20521 aatatatgtc ttatcatcta ggtggctgga cagaaaaaca aggtgaggta cttgcgacta
    20581 atctattaga aaatgaatcc cctcttccta ctgccattct tgtcgggagc gatccaatgg
    20641 caattggtgt ctatcgggca ttgaaacaaa aaaatatcca aattggagaa gagattgttg
    20701 tagcaagctt tgataatatc gagacaatcg caaacctctc ccctggcttg accagtgttc
    20761 aaatcaatgc gaaatcaatt gggcaagcag ctgttcgaat ggcattggag cgaattgacg
    20821 gtatacggga cgaaccaatc attttgactt atcctgcacg attgattgtt agggaaagtt
    20881 ttatcccaag aacaaaaagg tattgaaaga gaggttgtga aaagccgctt cgtttcttca
    20941 tactcaaaac gaaacggctt tttcacaacc tcttacttat acttattcac aaaatccaat
    21001 gtctgctggt aacaattttg cgattctttt agcgtgtaat caaattggta ttcatgggta
    21061 atctcttttt ttgtatctgt ataaaacaag gattgcacgg gtacctttaa ttctgtcaac
    21121 cgattttcta atgcttgacc ttgctcctgg aatgagtatg catttccgtc agttatatac
    21181 gttggcggaa attccttaga aacatggtca gccacactag cttctttcaa ttgctcactc
    21241 gttttccaat cttttgttcc aatcaacgac cacgcaacgg ttttgacgaa aaacttcata
    21301 aatcgatcat ccgaatgctg ctgtgctgtt agcttcaaat caacaggtcc gcaataagaa
    21361 atggttcctt tcagactatc ttttggaagt agctgtttga ttttcatttg tttagcatac
    21421 gcatcattcg tttgtatagc tgcatattgc aatgcgattt gtgaacctgc actatctcca
    21481 ccaaaaaata attgttccat gtctagcaat ttgtcgtctt tttcttcagc taataaatct
    21541 ttgatcagtt cattcacttg aagaacttga ttagggtatt ctgaatcagg cgctaattca
    21601 taattcatcg caaccactgc gatgttggcg tctgaaacta attttgtcgc aaattctttg
    21661 acacccgatt tatctccgcc gacgaatcct ccaccatgta cccaaaatag aacaggaaca
    21721 ggccccttgc tgttttttgg atagtagatg tcataagtat tctctttata cttggactca
    21781 tacgtcaaat ctgttttttt cgccacgttt ttttctgctt gatcgaacgt ttttttatca
    21841 gtgatttgaa cagtatttga aaacatatgg ttgatcaaga atgctccagg tctgggggaa
    21901 agctggaagg caagaaagat tgcaaacgcg atcccaagaa tgattccgaa gaaccatccg
    21961 ataaatttaa gaattttctt tttcataagg ctccctcagt agttagtatt aagcattctg
    22021 attataccat agtgttattt cctatcaagc tctcctagat gatttaatga ttttccccaa
    22081 acttcttctg caatgctttt gacaaaagaa attttttcca ttgttcttca aacaaaacat
    22141 tttcttcttc tgttgaagca aatccacatt gaggacttaa gcacaaacga tccaaaggca
    22201 gatatcgtgt cgcttcgtag atccggtcaa tcacttgctg gtgctcttcc atttcgccat
    22261 ttttcgttac agtcaaaatc taagacaact aatttatctt cagagacttt ctctaaaaga
    22321 acaaaactcc cagcacgttc actatcgtat tctaaataat aggcacggac attttcttga
    22381 gtaaaataat gggtctgcta cgtcgtcatc ccccctgatg ccgccaaaat cgaataataa
    22441 tttccgcgtc aaacatgtat atttagtgtt gaatcatttg agaatatgaa aataaaaatc
    22501 tttttgatca atcagttaat caaattgaaa taacgaaaaa tctgagacag aatgacgttc
    22561 attctgaccc agatttgatt ttgcacaact caacagtcct tattggcaaa tcgccaaaat
    22621 aatgtagact aactaaaaag actaagaaac aataacaaaa gttaacactt cttagtcttt
    22681 ctttagcacg tctatttatt aaagatttta gggccttttc tcatgttttt acgatcattc
    22741 ttaggtgttt ccatttgttt ggatcggcct ccaccttgtt tctttttgat caattctttc
    22801 attttttctt tttggtccat ttttattctc ctttaacgaa tgaagcgact aattcgatat
    22861 gatgggtttg cgggaaaaga tctacaggct gaactttctt cacggcataa cctgcttctg
    22921 caaataactt agcatctctt gcaaaagttg ccggattaca tgagatatag acgattcgtt
    22981 ctggtgacat ttcgattgct gattcaataa aatgatgatc taatcctttt cgtggagggt
    23041 caactacgat cacagatggt ttgatccctt tttcttgcca ttttttcata actttttctg
    23101 cttttccgac ttcataatga acattttcga ttttattatt taaagcattg aactgtgcat
    23161 cttcaattgc ttctggaata acttccatcc catacacctt atccactctg tctgctaaag
    23221 acaagccaat cgtacctatt cctgaataag cgtcgatcac aatgtctttt ttatctaact
    23281 cggcaaactc gatggctgtt tggtacagat actctgcttg ttgagtattt acttgataaa
    23341 atgactttgc tgagattcga taggtttttc ctaatagctg atcttcgata tagtctctgc
    23401 catataaaac tttttctttg tctcctaaaa tcacatttgt tttttcttca ttgatatttt
    23461 ggatgaccga aaccacttct ggcaattctt catgaatagc ttcagcaatt tccttggatt
    23521 taaagaattt ttctttacga gtaactaaaa cgaccatcat ttcatgggaa taatgaccac
    23581 gacggataat gatgtgacga agctgtcctt catttttttc ttcattatat cctcgtactt
    23641 ggaaccgttg caagatatct ctgactactt tgattgcttg atcgatgaca ggatcttgga
    23701 tataaaaatc ttcgataggg actagatcat ggctattctt tttgtaaaaa ccggtggcta
    23761 actgtccatc gatacggcga acagggatct gtgctttatt acggtagccg aatggttctg
    23821 ccattccgac cgttggaagt acaggaactt ctggcatctt agcaatcttc gccattacat
    23881 gctctacttg tttttgtttg aagacaagct gttgttcata cttcaaatgg gctaaaggtg
    23941 cgatacctat gcgaagtaat gcattgtttt ctacaggctg acgatcaggt gattgtgtaa
    24001 taaatgtttc gacttttcca tatccaaact tattgcctgc ttttactact agtatttcta
    24061 cttcttctcc agggagtgca ttttcgataa ataatggata accatcgatt tttgctaccc
    24121 ccattccttc ataactcaag tcgacgattt cgactgtata tcgttcgttt ttctttacta
    24181 tttgctgttc tgtcatattt tgctccttta agcctatttt tcaatcctac tgaactctac
    24241 tataaatcag ctaattacac aactaaaacc ggcactgacc ttactacgtt cagcaccggc
    24301 ttttgattaa ttcttttgat taggtgtttc gtctgctatt tttccgtcac cgtcgatatc
    24361 ttcatccgtt aaacgttcga cttcttttac gaattctttg ctgacaacct ctaattcttc
    24421 ttcatctgta cctgtgattg cttcatcagg aatctgatcg gtattggcaa agaactcaat
    24481 gtgttgatga agattttgga aatgcatcgg tgcttccccg ccgtattcac catctaagtt
    24541 gatcattact ggtcgattga tatcatcttc tgtttcaacg aacaaactgc ttgttttggt
    24601 atagattatt cttggatcat cgacatgtcg accgccattc agcatgagtg ctgcaatatg
    24661 caagatctca aagatatttg ctgtcttcac aatgattaaa gaaaacttcc catcatccaa
    24721 tttggcatct ggcgcgatct gttcgaatcc tccaacagag ttcgtcagcc ctaggaaaaa
    24781 catcgaagca tttccgatat attccccttc atcatacttc aagcgcattt tgattggctt
    24841 tactcgaggg agcatctctg ctcctttcgc aagataagca agataaccaa aaatactctt
    24901 tagttctgat ggaacttcat aagtcaattc tgtcaaatag ccacctgcag cgatattgat
    24961 gaagtaactg ttatcagaaa ggccgatgtc catttttacg gtttggtgtt tttttatcac
    25021 ttctgctgct gctttaatat tatctctagg aatttttaat gctcgagcat agtcgttcgt
    25081 tgtaccagct gggatgatgg ccattttagg acggtgttca agcggagcga ttccattaac
    25141 cacttcgttg attgtgccat cgccaccagc tgccactact agatcaaaac ctagttctgc
    25201 gactctacat gcttcattct tggctgaatc tggttctggt gtagttgcat aggcgctggc
    25261 ttcaaatcct gcttcttcta atgcctgtag gatatccgcc aaattttttt tcaataattc
    25321 ttttcccgag gtggggttat aaattacgcg tgcttttttc attttcagcc tctatcgttt
    25381 cgctaattca tctttaagta gcttattcac gacaccagga tttgcttgtc ctttagttgc
    25441 tttcatgatt tgaccgacta ggaagccaac cgcacgatct tttccatttt tgaaatcatc
    25501 gacagattgt tggttgttat ccaaaatttc attaatgatt ggcagtagtt tgttcggatc
    25561 agataattgc acccaaccat ttttttcaac tacttcttgg gcttctccgc catttgtgat
    25621 caattcacgg aagacttttt tggcgatttt tgagctgatc gttccatcgg cgatcaaacg
    25681 aatcattcct gctaagttct caggtgtcaa ttttgtctca gctaattcca gtttctcact
    25741 gttcaagtaa gcagaaactt cacccatcaa ccagttagat gcttgcttgg catctgcacc
    25801 attttccaaa acagcttcaa aaaaatcaga catttctttt gtaagtgtca ataccattgc
    25861 gtcatactct ggaagtccaa actcacggat atagcgttcg cgacgagaag ctggcatctc
    25921 aggcaaacta gcttttactt tttgaatcca ttcgtcatcg atcacgaatt tcgggatatc
    25981 aggctctggg aagtaacgat aatcactaga cccttctttg acacgcatca aaactgtttt
    26041 attcgttgtt tcgtcaaaac ggcgtgtttc ttgttggatt tctcctcctg aaagaagaac
    26101 ttttgcttga cgtttttctt caaaagctaa accttttttc acgaaagata aagagttcaa
    26161 gtttttcaat tctgctttcg taccgaactc ttcttgtcca taagggcgaa gagaaatatt
    26221 ggcatcacag cgcatagagc cttcttccat tttcacatcg ctgacttctg taaattggat
    26281 aattgatcgc aatgcttcta gataagcgta tgcttcttct ggtgaacgca tatcagcttc
    26341 agaaacgatt tcgatcaaag gcgtgccttg tcggttcaaa tcaacgtaag aataaccgcc
    26401 aataccatgc atgttttttc cagcatcttc ttctaaatgg acacgttcga tccggatttt
    26461 tttcttttta ccttctactt cgatttcgat ccatccgtca tgaccgattg gttgatcaaa
    26521 ttgggaaatt tgatatgctt ttggattatc tgggtaaaag taatttttcc ggtcaaaatg
    26581 agtatcttta gagatttcac agtttaatgc caaagctgct ttcatcccga attccagcgc
    26641 agctttattc attactggca gcacgcctgg ataaccccag tcgatcacgt ttgtattgct
    26701 gtttggttct gcaccaaaat gagctggcgc tggagagaaa atttttgagt tggtttttaa
    26761 ctcgacgtgg acttctagtc caatgactgt ttcaaaattc attcgtcttt ccctcctaaa
    26821 atagctggtt gttgtttatg gaattctgtt gcttgttcaa acgcatatgc cgcttgatac
    26881 atcgtttttt catcaaaata attaccgatg atctgcaatc caactggtaa tccttctgat
    26941 aaacctgccg gtacagacat acctggaagt ccagccaagt tgacagggat cgttaagatg
    27001 tcactcatgt acattgtgat tggatcgtta atgttctcac cgattccgaa tgcaactgtt
    27061 ggtgaagatg gcccgatgat caagtcataa tctgcaaaga ctttttcaaa atctcgtttg
    27121 atcaatgtac ggacttgtcc tgcttttttg aagtaagcgt cataataacc cgcgcttaag
    27181 gagaatgtac ctaacatgat acggcgtttt acttcttcac cgaatccttc tgaacgtgag
    27241 ttgacatata catcatctaa tgatttcaca ttttcagagc gataaccgta gcggatacca
    27301 tcgaatcgtt gcaaattgga acttgcttct gatgaggcaa tgatataata aacagccaca
    27361 ccgtattttg aatgaggcaa gctgacttct tccacaacag cacctaatga acggaatgtt
    27421 tctgctgctt tcaatacagc ttcttttacg ccaggggcca caccttcgcc taagtattct
    27481 ttaggtaaag caatcttcat tcctttgatg tcgcctgtca gtccctctgc aaaatcagga
    27541 actgaaacgc ctgaagaagt accgtctttt tcgtcataac cgctgatagc tgtcaatgct
    27601 aatgcattat ctttcaccgt acgggtcatt ggtccgattt ggtcaagaga tgaagcaaag
    27661 gcaatcaaac caaaacgtga gacacggcca taagtaggtt tcatccctac gatgccgtta
    27721 aaagctgctg gttggcggat acttccccca gtatcactac ctaaagaaac tggaatttgt
    27781 ccagctgcaa ctgctgctgc agaaccacca gaagagccac caggtacttt tgttgggtcc
    27841 caagcatttt ttgttttctt gaaataagaa gtttctgtac ttccacccat agcaaattca
    27901 tccatgttta gcttaccaac agggatcata tctgcttgat agattttatc catgaccgtt
    27961 gcatcataaa ttggttcaaa attgtaaagg atcttagatg cagcggttgt caagatatct
    28021 tttgttacga tattatcctt gataccaatt ggaataccag caaggacgtt gctttcatca
    28081 atcccttttt catctaaagc ttttgcctgt tccaatgctt tttcttcgtt caatgtaatg
    28141 aatgcctcga cctcaggctc tgtttctttg attcgttcaa atgttgtttt tgtcaaatct
    28201 tgtacagtga tttctttcga tacaagcata tgatgcagtt cttctagaga acgattgtgt
    28261 aattctgtca ttatgcgcca gcctccccat tatcgatgat tgcgggtact ttgataaagc
    28321 cgtcttctgt ttccggcaca tttttcaata attcatcgcg gttccatcca gcttgcgccc
    28381 gatcttgtcg catcacgttt actgtttcaa ccacattcga cgtaaatgga acaccttccg
    28441 tatctacttc ttccagcatt tcaaccatat cgatgatttt acctaattgg tcggtaaaac
    28501 ttgcaagttc ttcatctgcg aacgcaagtt ttgctaattt ggcaacgtgt ttcacttgtt
    28561 cttcactaat cgccatacta ccccttcttt ctaaacgagt taaaaacttt gctctctatt
    28621 ttaacacaag agtgccgtgt ctgaaattgt ttattgaaat ttgtctgaaa aaactcattt
    28681 ttcattcttc tactgagcga cttttagcca atgcatctgc catttgatct tctgtccaaa
    28741 cttcgattcc taattcttgt gctttggtca gcttgctgcc agcatcttct cctgctacca
    28801 cgatatccgt ttttttcgat acgctaccag tcactttccc gccaagattt tcgatcgtct
    28861 cttttgcttc ttcacgagta aatcgtgtta gtttaccagt aaggactact gttttttctt
    28921 taaaaggaga ctcgacttct tgcaattggg catttcgaag ccctttgtat tcgaaattga
    28981 cgcctgcttg ttttaattca ttcatcaatt catggacttc ttcgttactg aaataagtga
    29041 ctacactgtc ggcaatgata tcaccgatcg tatcaagcgc aataatcgac tcatagtcac
    29101 ttttactcaa tgtttctaga tcaccgaaat gttctgctaa aatttttgct gctttcgctc
    29161 cgacatgtcg gattcctaac ccgaaaatca accgctcgac cgaattatct ttgctgttgt
    29221 cgattgctgt caaaatatta tttgctgatt tttcttttat tttgtccaac gtcaataact
    29281 cttcttctgt caatttgtaa agatcagcaa catctgctac tagtttttta tcatacatct
    29341 gttctagtac gcgcggcccc aacccatcga tattcatcgc atttcttgaa acaaagtggt
    29401 tcaaaccttc tttcatttga gcagggcatt taggattgat gcaccgtaag gctacttctt
    29461 catccaaatg gacaagttca cttccacaaa ctggacaatg tgtaggcaat tggtattctt
    29521 cgctgtcttt aggtcgttta tctaacacga cttgcgaaac ttctgggatg atgtctcccg
    29581 ctttataaat cagaactgta tctttcaagc ggatatcctt caacttaata taatcaccgt
    29641 tatgcaggct ggcacggctt actgtcgttc ctgctactcg gactggtgtc atgatagctg
    29701 ttggcgttac tacccctgtt cgaccgactg tccattcgat gttttcgatt agcgtttcaa
    29761 cttcttctgg cggaaacttg taagctgctg cccatctcgg tgctttgata gtaaaaccaa
    29821 gttgatcttg tagcgagaat tcattcactt tgatgacgat tccatcgatt tcatagggca
    29881 aatccacacg tttgtcatga tattcttcaa tgtatgacca cacttcatca atcgaatgac
    29941 atagacgttt ttcccgattc gtgtggaatc caattttttc tagctcttct agcgcatcat
    30001 actgggtttt tgcttgcata ggaccgaaat cagctactgt gtataaaaaa gtgtccagat
    30061 ttcttttcgc tgtgatttta gaatctaact gacgcaaaga accagctgcg gcgttccgag
    30121 gattcgcaaa gatatctttt ccctctgctt ctctgtcttg gttcaattgg acaaatgacc
    30181 gttttggcat gaaacattcg cctcttactt cgatgttcat tggttctttt aatttgattg
    30241 ggaccgaccg gacagttttt aggttttcag tgatgttttc tcctacagtt ccatccccgc
    30301 gagtcgcacc tctcacgaaa tttccatctt cataacgcaa agaaacggaa agtccatcta
    30361 tttttagttc acagcaatag tcaactacac gtcccactgc tttttgtaca cgttgatcaa
    30421 aagctatcag ctcttctttg ctgaaaacgt cgttcaaact gtaaagcgga atatcatgag
    30481 tgactttttc aaaaccttct aatacttttc cgcctactcg ttgagtggga gaatcagacg
    30541 tgatcaaatc aggatattgt tcctcgattg ctactaattc tgcgtattct ttatcataaa
    30601 catagtcttc cactgttggt ttatcttcta cgtagtattc gcgagaccat tggttcagtc
    30661 ttgtacgaag ttcttctgct cgtttagcag cttcgtcaat cgtcatttca tgttccatca
    30721 tttaccctcc actactaagc tttttcaatt ggcgcaaagg cagccaaaag acgttttact
    30781 ccttgacttg ggaaagccac atctagttct agatccttcg acgtcccgct tactcggacg
    30841 actgttccta gaccccattt tttgtgtttg actttatctc caggtttcca gctgttattt
    30901 tcccctccag tagcactttt agagggaaca accgctgtct ctggctgttt atagctatat
    30961 gctgtttttt tagcgaatac aggcgttttt ttaggcgtag gacgcatgcc ttcgatttcc
    31021 agtaactcct gatcgatttc ttctacaaaa cgagaaggtc ggttatattg cgtccgtcca
    31081 tataatgttc tggagaaagc atttgttaaa tacaacgctt cttctgctcg cgtgatcccc
    31141 acatatgcga gacggcgttc ttcctccagt tcgctttctt ccatcaatgc tcgagataaa
    31201 ggaaaaaccc cctcttctag accaatcagg aatacaactg gaaattctaa tcctttggct
    31261 gcatgcaaag tcatcaatgt cacttgggaa gcatcttctt ctaaattgtc aatgtcggaa
    31321 acaagtgcca gatcatttaa gaagaccgtt agtttttctt ctggtgcatc agcgtcttct
    31381 tcattttgct gttcgaattg tttgtcgaat tcttgtgtga ccgttaaaaa ttcctccaag
    31441 ttttcgatgc gtgcttgtgc ttctaatgta ttttggattt ttaagtcttc tagatatccg
    31501 ctacgatcca aaacctcttt cgtcaattct gtcactgtca agtatgggat catctgagtg
    31561 acttcttgga tcatctctcc aaatgcacct aattgctgtc ctgcttttcc accgatattt
    31621 gccagatcca cattttgcgc tgcttcaagc agtggccatt catgaagaga agcaaaactg
    31681 cgtagttttt cgatagatcc tggtccgatg cctcgtttgg gcgaattaac gatacgctca
    31741 aaactgattg aatcttgagg atttaccagc acattcaaat acgctaaaat atctttgatt
    31801 tctttacgat cgtagaactt gtgccctcca accattttat aaggaatatt tgctttcaac
    31861 agagtttctt ccattacacg agattgtgcg ttcgtccggt acaagatggc aaagtcgccg
    31921 taattccgat gattgcttcg aatctcttct tgcatccggt ctacgataaa acgggtttcg
    31981 tctcgttcat tatctgcacg gtagtaagtg atcttgtttc cttctttgtt ttctgtccac
    32041 aagttttttg gttttcgatt gctattgttt tcaatgactt ggtttgctgc gctaaggatg
    32101 tttttcgtgg agcgatagtt ttgttctagc aaaattactg cagcatctgg ataatctttt
    32161 tcaaaatcca agatgttctg catatctgca ccgcgccagc cgtaaatact ttgatctgca
    32221 tctcccacga cgcacaggtt cctaaatcta cctgccaata aattgactag cgtatactgt
    32281 gcgtgatttg tatcttggta ctcatctaca tgaatataat ggaatttgtt ttgataatac
    32341 gtgagtgaat caggatgttc ttcaaataat cgaatcgtat tcatgatcag gtcgtcaaag
    32401 tccatacatt gattatattg aagctctttt tggtaagcag cataacattt tgccgcaatc
    32461 tcttcgtaat aactgccttg catttttgca aaatcctgag gggtctgcag gctgtttttt
    32521 gcttgagaga ttgttcctaa tatacttcga ggatcatatt ttttcggatc aatgttcagt
    32581 tcttttagta tccgtttcat caaggtcagc tgttcagaag aatcgatgat tgtaaagttc
    32641 cggttatacc cgataaaatc aacatctctt cttaaaatac gcacacacat cgagtgaaaa
    32701 gtcgataccc agacatcttc gcctccagat gcgagaatcg cattgacacg ttctttcatt
    32761 tcttttgcag ccttattggt aaaagtaatc gctaggatgt tccaaggatt gacttctttt
    32821 tcctcaatca aataggcaat gcggtgtgtc agcactctcg tctttccact tcctgcacct
    32881 gccattagca gtaatggtcc gtcagtgtga agaacagctt ctttctgacg ggggttcatc
    32941 ccgtttaata attcagcttt ggatgacatt aacaacatcc tttcttttat caatcttgtt
    33001 aattatagca ttttcttggc tttcattaaa ctagctagtt caaaatcatt tgtttctttt
    33061 tatggatttt tccttgtcaa ttcgttgatt tcgcgctaaa ttaaaagaaa gcgaggcgtt
    33121 tgaatggaaa aaaaaggaaa aatcaagaaa ttagataaga ctcagatata ttttattcta
    33181 aaaggaatat ttgttggact gctgacagga atcgtcgtta gcctgtttcg attatctatc
    33241 gaaaagctaa gcgatttagt tcgaagtatc tatgaaatga gtcgggaaca gccgatttac
    33301 ttaattggcc tagctatttg ctgcatcctt gcagcatttt tcgtgggtta tctggtcaaa
    33361 aatgaaccgg atatcaaggg aagcgggatt ccacaagtag agggacagct tcgcggggaa
    33421 ttatcaatga actggttctc tgttttatgg aaaaagttca ttggcggtgt actttcagtt
    33481 ggtgcgggcc tttttctagg tagagaagga ccttctatac agcttggcgc atccattgga
    33541 caaggagctg gacaattgtt tcggagtcca tcttcagaag aaaagatttt aatttctagc
    33601 ggtgcaagta gcggacttgc agcagcattc aatgctccta tcgcaggatt actctttgtt
    33661 ttagaagaaa tccatcactc cttttctcca cttgtttggc tgacatcatt tgcttcagca
    33721 atcactgcta acttcgtctc tctttacttt ttcggcttga gacctgtttt atatctaggt
    33781 gaccttcctt ctttgccgtt gaaatattat ggttccttag tgatcttagg agtacttcta
    33841 ggcatcttag gttttattta tcagaatgtc ttgctggctt tgccaaaatt ttacaaccga
    33901 ttgcctttac cagcttattt tcacgggttc gttcctttct tgctgatttt gccaattggt
    33961 tatttatggc ctagtactct aggcggaggc aatcaaatcg ttttagcttt tggacatgct
    34021 tccttgccaa tcattatgat tatcggtttg tttgttcttc gattcgtttt ttccatgatt
    34081 tcttacggtg ggggtcttcc aggggggatt ttccttccga tattgacatt gggggcttta
    34141 atcggtagct tttatggaaa cattatggtt gatttcggga tggatccaat ctacatcaag
    34201 gattttgtcg ttattgccat ggctggttat ttcacagcga ttggaaaagc accgctgaca
    34261 gcaattattt tagtgacaga aatggttggc tctcttaatc atctgatgcc tttaggattg
    34321 gctgctcttg ttgcttatat cgtcaatgac cttctcggcg gtaatccaat ttacgaatca
    34381 ttattggaac gtctacttgg aaatactcag accgcctcac taaaaggtgc aaggacaact
    34441 tttgattttc cagtaacggc agagagttct ttagacggat taatggtacg agacttcaat
    34501 tggcctaaaa atatgctgct aatctctata cgcagaggaa atcaggaaat cttgactcac
    34561 ggtgatacga tcatgaatgt aggagatatt ttggttatct tgactgatga agcaaacttg
    34621 ccaagaatca agcaggaaat cgaggctaaa tcttctatca caaatttgaa gcaatcattt
    34681 taacgaacat ggaaaaacta ttttacaaca actattcatc tacactactt gattctatat
    34741 gattctataa aaaaagaaga ggctgggaaa a
//
LOCUS       DAFLWC010000020        34510 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.020, whole genome shotgun sequence.
ACCESSION   DAFLWC010000020 DAFLWC010000000
VERSION     DAFLWC010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34510
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.020"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            212..604
                     /locus_tag="L1V17_000920"
     CDS             212..604
                     /locus_tag="L1V17_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBN1235704.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="L1V17_000921"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="L1V17_000921"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HBN1235705.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="L1V17_000922"
     CDS             3165..4775
                     /locus_tag="L1V17_000922"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HBN1235706.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="L1V17_000923"
     CDS             5067..5936
                     /locus_tag="L1V17_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HBN1235707.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="L1V17_000924"
     CDS             6101..7372
                     /locus_tag="L1V17_000924"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBN1235708.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="L1V17_000925"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="L1V17_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBN1235709.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="L1V17_000926"
     CDS             8763..9026
                     /locus_tag="L1V17_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HBN1235710.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="L1V17_000927"
     CDS             9471..9920
                     /locus_tag="L1V17_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1235711.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="L1V17_000928"
     CDS             9977..11395
                     /locus_tag="L1V17_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1235712.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="L1V17_000929"
     CDS             11395..12255
                     /locus_tag="L1V17_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBN1235713.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="L1V17_000930"
     CDS             12429..13202
                     /locus_tag="L1V17_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBN1235714.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="L1V17_000931"
     CDS             13349..13714
                     /locus_tag="L1V17_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HBN1235715.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="L1V17_000932"
     CDS             complement(13862..15070)
                     /locus_tag="L1V17_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1235716.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="L1V17_000933"
     CDS             complement(15089..15367)
                     /locus_tag="L1V17_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235717.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15521..16216
                     /locus_tag="L1V17_000934"
     CDS             15521..16216
                     /locus_tag="L1V17_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBN1235718.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(16658..17455)
                     /locus_tag="L1V17_000935"
     CDS             complement(16658..17455)
                     /locus_tag="L1V17_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HBN1235719.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="L1V17_000936"
     CDS             complement(17452..18636)
                     /locus_tag="L1V17_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBN1235720.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="L1V17_000937"
     CDS             complement(18661..19908)
                     /locus_tag="L1V17_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBN1235721.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="L1V17_000938"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="L1V17_000938"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBN1235722.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="L1V17_000939"
     CDS             21888..22202
                     /locus_tag="L1V17_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBN1235723.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="L1V17_000940"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="L1V17_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBN1235724.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /locus_tag="L1V17_000941"
     CDS             22887..23531
                     /locus_tag="L1V17_000941"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HBN1235725.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="L1V17_000942"
     CDS             23546..23875
                     /locus_tag="L1V17_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HBN1235726.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="L1V17_000943"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="L1V17_000943"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBN1235727.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="L1V17_000944"
     CDS             24863..25687
                     /locus_tag="L1V17_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBN1235728.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="L1V17_000945"
     CDS             25680..26027
                     /locus_tag="L1V17_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HBN1235729.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="L1V17_000946"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="L1V17_000946"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBN1235730.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="L1V17_000947"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="L1V17_000947"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBN1235731.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="L1V17_000948"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="L1V17_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBN1235732.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="L1V17_000949"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="L1V17_000949"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HBN1235733.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31657..32451
                     /locus_tag="L1V17_000950"
     CDS             31657..32451
                     /locus_tag="L1V17_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1235734.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="L1V17_000951"
     CDS             32441..34483
                     /locus_tag="L1V17_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1235735.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
BASE COUNT        11095 a         6120 c         7248 g        10047 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtag ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcgaaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat
//
LOCUS       DAFLWC010000021        34422 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.021, whole genome shotgun sequence.
ACCESSION   DAFLWC010000021 DAFLWC010000000
VERSION     DAFLWC010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34422
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.021"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            352..1041
                     /locus_tag="L1V17_000952"
     CDS             352..1041
                     /locus_tag="L1V17_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1235736.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1028..2236
                     /locus_tag="L1V17_000953"
     CDS             1028..2236
                     /locus_tag="L1V17_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBN1235737.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2530..3801
                     /gene="serS"
                     /locus_tag="L1V17_000954"
     CDS             2530..3801
                     /gene="serS"
                     /locus_tag="L1V17_000954"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBN1235738.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4350..5834)
                     /gene="guaB"
                     /locus_tag="L1V17_000955"
     CDS             complement(4350..5834)
                     /gene="guaB"
                     /locus_tag="L1V17_000955"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBN1235739.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6339..7034)
                     /locus_tag="L1V17_000956"
     CDS             complement(6339..7034)
                     /locus_tag="L1V17_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HBN1235740.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7124..8224)
                     /gene="ychF"
                     /locus_tag="L1V17_000957"
     CDS             complement(7124..8224)
                     /gene="ychF"
                     /locus_tag="L1V17_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBN1235741.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8233..8424)
                     /locus_tag="L1V17_000958"
     CDS             complement(8233..8424)
                     /locus_tag="L1V17_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBN1235742.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8445..9335)
                     /locus_tag="L1V17_000959"
     CDS             complement(8445..9335)
                     /locus_tag="L1V17_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBN1235743.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9322..10089)
                     /locus_tag="L1V17_000960"
     CDS             complement(9322..10089)
                     /locus_tag="L1V17_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBN1235744.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10101..10814)
                     /gene="rsmG"
                     /locus_tag="L1V17_000961"
     CDS             complement(10101..10814)
                     /gene="rsmG"
                     /locus_tag="L1V17_000961"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBN1235745.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11046..12947)
                     /gene="mnmG"
                     /locus_tag="L1V17_000962"
     CDS             complement(11046..12947)
                     /gene="mnmG"
                     /locus_tag="L1V17_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBN1235746.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(12964..14361)
                     /gene="mnmE"
                     /locus_tag="L1V17_000963"
     CDS             complement(12964..14361)
                     /gene="mnmE"
                     /locus_tag="L1V17_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBN1235747.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14660..15043
                     /locus_tag="L1V17_000964"
     CDS             14660..15043
                     /locus_tag="L1V17_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235748.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15211..15969)
                     /locus_tag="L1V17_000965"
     CDS             complement(15211..15969)
                     /locus_tag="L1V17_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HBN1235749.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(15987..16805)
                     /locus_tag="L1V17_000966"
     CDS             complement(15987..16805)
                     /locus_tag="L1V17_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBN1235750.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(16802..17158)
                     /gene="rnpA"
                     /locus_tag="L1V17_000967"
     CDS             complement(16802..17158)
                     /gene="rnpA"
                     /locus_tag="L1V17_000967"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBN1235751.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17276..17410)
                     /gene="rpmH"
                     /locus_tag="L1V17_000968"
     CDS             complement(17276..17410)
                     /gene="rpmH"
                     /locus_tag="L1V17_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBN1235752.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            17933..19267
                     /gene="dnaA"
                     /locus_tag="L1V17_000969"
     CDS             17933..19267
                     /gene="dnaA"
                     /locus_tag="L1V17_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBN1235753.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19465..20595
                     /gene="dnaN"
                     /locus_tag="L1V17_000970"
     CDS             19465..20595
                     /gene="dnaN"
                     /locus_tag="L1V17_000970"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBN1235754.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            20824..21066
                     /gene="yaaA"
                     /locus_tag="L1V17_000971"
     CDS             20824..21066
                     /gene="yaaA"
                     /locus_tag="L1V17_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBN1235755.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21053..22177
                     /gene="recF"
                     /locus_tag="L1V17_000972"
     CDS             21053..22177
                     /gene="recF"
                     /locus_tag="L1V17_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBN1235756.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22174..24120
                     /gene="gyrB"
                     /locus_tag="L1V17_000973"
     CDS             22174..24120
                     /gene="gyrB"
                     /locus_tag="L1V17_000973"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBN1235757.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24140..26611
                     /gene="gyrA"
                     /locus_tag="L1V17_000974"
     CDS             24140..26611
                     /gene="gyrA"
                     /locus_tag="L1V17_000974"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBN1235758.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDIAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            26847..27146
                     /locus_tag="L1V17_000975"
     CDS             26847..27146
                     /locus_tag="L1V17_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBN1235759.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27196..27708
                     /gene="ssb"
                     /locus_tag="L1V17_000976"
     CDS             27196..27708
                     /gene="ssb"
                     /locus_tag="L1V17_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBN1235760.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27734..27970
                     /locus_tag="L1V17_000977"
     CDS             27734..27970
                     /locus_tag="L1V17_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBN1235761.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28113..30086
                     /locus_tag="L1V17_000978"
     CDS             28113..30086
                     /locus_tag="L1V17_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HBN1235762.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30092..30544
                     /gene="rplI"
                     /locus_tag="L1V17_000979"
     CDS             30092..30544
                     /gene="rplI"
                     /locus_tag="L1V17_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBN1235763.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            30818..32185
                     /gene="dnaB"
                     /locus_tag="L1V17_000980"
     CDS             30818..32185
                     /gene="dnaB"
                     /locus_tag="L1V17_000980"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBN1235764.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            32965..34257
                     /locus_tag="L1V17_000981"
     CDS             32965..34257
                     /locus_tag="L1V17_000981"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBN1235765.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10505 a         6693 c         6817 g        10407 t
ORIGIN      
        1 tttccaacat gtcaacaact tattttttat tatttaataa gttattggtg ttcttttgaa
       61 caaataataa tatatcaaca tcacatgtga aagtcaataa gaaaatgctt atttatcaac
      121 atttctagct tacatgatca ttggttagtt ctggtccttt ttcgttcgtc tttataactc
      181 cgagagacgt aaaatccttt tgttttcagt ttaatgttca tgttcttgtc ttattcacac
      241 caactagatg tctcaccttc taaaattttc cttaacaaag tgctgctttt atctatttct
      301 gctttttttt gctagaataa tagtaacaat atgactctgg aggatttatt tatgaaaatt
      361 ttgattgctg acgatgataa agaaatcgtt gaattattaa gtatctatgt tcacaatgag
      421 gggtatgaag cagtaaaggc ttatgatggg aaagaagcat tatctaaaat cagaacaatc
      481 cctgatattg aattacttat tttagatatc atgatgcctg agatggatgg gatgcaagta
      541 gtgaaagagc tacgaaaaga atcccaaata ccaatcatta tgctgacagc aaaaactact
      601 gatatggata agatcaaagg actggtcgct ggtgcagatg attatgtgac caagccattt
      661 aatccgttag aagtaatggc tagagtaaag tctttattac ggcgtacaaa aatgcagatt
      721 gccccagatc agcctgatgt attagaagta aatgcattaa tcatcaataa agactctcat
      781 gaagttaaaa caatcgatgg gaaagaaatc cagttaacag ctttggaatt cggtatcctc
      841 tacttgcttg ctagtcatcc taatcgagta tttagcgcgg atgaaatttt tgagcgtgtt
      901 tggaaacaag aaagtattgt ctctgctaaa actgtcatgg ttcacgttag tcatttaaga
      961 gataagattg aagaagcaac tggtggtgaa aaagtcattc aaaccgtttg gggagtgggc
     1021 tataaaattg acgcaagata gtaaacgagc aactgaaaaa cgccgtcgga tcaatttgac
     1081 ttcaaaagaa atcagcgaat tgttagcgga aggaatcatc acgattatcc ttttgcttct
     1141 attaaatgtt tctattctgg ttgttatcag ttcggtgatc aacagttcac cttctttgac
     1201 gaatgcgatt tgggattcaa agaatatttt tgcagaacga ttgaacactg atttgttctg
     1261 gaacggccgg aattttatta ttcccttttt ctttctatta gatattggtg ttttgtattg
     1321 gcgcttgatt cgaagatatc gccaaatgca attgcggcat atcatcagcg aacttcacta
     1381 catcgcaaac ggaaattatg atcatcgtat cccttttgaa ctgagtggtg acttaagccg
     1441 agtggtaaca agtatcaatg gattggtgga tagtaccgta gcagcgattg aagacgaacg
     1501 taaaatcgaa aaatcaaaag atgaattgat cacgaatgtc agtcatgata tccgtacccc
     1561 actcacgtcc atcattggat acctaggact gatagaagat ggccagtatc actcagaaga
     1621 agatctttta aagtatacgc atactgctta tatcaaagca aagcagatga aatctttagt
     1681 ggacgactta tttgaataca ctaaggtacg ccagcctgct gtcccggtga atttttctgc
     1741 ctttgacatg atccagttga tcgaacagtt agcagctgat tttgagttgg aagcttctaa
     1801 aaaaaatatc caaatacttg ttcaatcaaa agtagactcc cttatcatgg atggcgatac
     1861 cgaaaaactt gtacgtgtct tcaataatct tttgacgaat gcgttgaaat acggaaaagg
     1921 agcaacgaag atcgtaatcg aagtagaacg tatcggttca gaagttgttg caacagtcaa
     1981 aaataacgga gcaatgatcc cacaacaggc aatcgataat ctattcgacc gtttttatcg
     2041 tgtagaagaa tctcgttcac aagcaactgg aggaactgga cttggtttag caatcgctca
     2101 aagcattgtg gctttgcacg gcggatacat ttatgcaaaa tcagataagc aatggacttc
     2161 tttcatcatg caccttccaa tcaagaaaaa tgaaaaatta cctattgata cacaggaagt
     2221 tattgacgaa agctgaaata ttcgctattc ttattacaat tattagaata aatgaaaaac
     2281 acagaaccca gtacacttta ttctttttca gagagctgat ggcaggtgta aatcagcaaa
     2341 ggataatttg gaagttccag ttcgtttacg tgccctttcg aaataagaaa ggtcggttca
     2401 acagccgtta tgtgttcaac aagtgcagct gacgctgaac ttgggtggta ccgcgaattt
     2461 cagactgatt cgtcccaaga ataatgggat ggatcagtct ttttttattt tcaaaaagga
     2521 ggaaatcata tgttagatgt aaaaatgatg cgacaaaata ttgaagaagt acaagaaaaa
     2581 ttgatgactc ggggcgtaaa aaaagaaaca ttagctgaat tcatggaact agatgaaaat
     2641 cgtcgtaagc tactagtcaa aagtgaagaa ttaaaaaaat atcgaaatga tgtttctgct
     2701 gagatcgccc aattgaagcg tgcaaaagaa gatgcttctg ctaaaatcgc tgaaatgaaa
     2761 gaagtcggtg gcaacatcaa agcattggat actgaaattg ctgaagtgga tgaaaaattg
     2821 aaacaaattg caactacttt gccaaacctt ccccatgatt ctgtgccagt tggaacagat
     2881 gaagaggaca atgtagaaat ccgtcgttgg agcgaaccac gtacatttgc ttttgaacca
     2941 aaaccacact gggaaattgc agaaaatctt gatattttag attttgaacg tggcgcaaaa
     3001 gtagccggta gccgttttgt ctattacaaa ggattaggtg ctcgattaga acgtgctgtc
     3061 tacaacttca tgcttgatca gcatatttac gaacacggct atactgaaat gatcactcct
     3121 tatatcgtca acagtaaagc gatgtttggt acgggacaat ttccaaaatt caaagaagat
     3181 gttttccaat tggagaatac tgatctaaca ttaatcccaa cagctgaagt accattaact
     3241 aactattata atgatgaaat tttagatggt gcagatttac ctatttattt cactgcacta
     3301 agccctgctt ttcgttctga agccggaagt gctggtcggg atacacgagg actgattcgt
     3361 cttcaccaat tcaataaagt agaaatggtc aaattttcgg atgtagagca ttcttacgaa
     3421 gaattggaaa aaatgacagc tgatgcagaa gatatcttga aaaaattgca tttgccttat
     3481 cgtgtgatgg ccttatcaac tggagacatg ggcttttctg cagctaaaac ttatgactta
     3541 gaagtatgga tacctgcaca agatacttat cgtgaaatca gttcttgttc taactgtgaa
     3601 gatttccaag cacgccgcgc aatgatccgt tatcgcgata atgatggaaa aatccactat
     3661 actcatactc tgaatggttc aggacttgca gttggccgta cagtagctgc cattttggaa
     3721 aactaccaaa atgaagatgg ttctgtcaca gttccagaag cgctcgttcc ttatatgggg
     3781 aatctgaaag ttattaaata aagaggctgt gaaaaagccg cttagtttcg agtattaaga
     3841 aaaattttgt gaaaatggct ttccacattt ttgcataaat tggacttaat accgagaaac
     3901 tggcttttga acaccattta tcgagaggtt gtgaaatcag cgaattaacc tgagtattag
     3961 agaaaaaaat ggaaaaatag tccctcatat tttaccgttt gttgaactaa taccgagggt
     4021 cagctgattg aacaccgttt agtggagagg tcgtaagcct accccccagc tcctagttac
     4081 aaggacaaat tcaaaaaaca gctcttcata ttttatgaat gttgtacttg tgattcggag
     4141 gtggcaaggg aacactgttt attcaaaaag aggctgggac agaagcgttt aactccaaga
     4201 aataagaaga aattcacgaa aattgctttt caaatttttg tgaatttctt cttatttccg
     4261 aaggagttgc ttctacttcc gccgtttata cgtgtttaga gcgtgagaca aaagtgttct
     4321 ttacttttgt cccacgctct ttaatgtttt taagattcaa ctgaatagtt tggtgcttct
     4381 tttgtgattt gtacatcatg agggtgtgat tcttttaatc cactgccgct catttggata
     4441 aattgcgctt catcacgtaa ttgctgtaga ttggctgccc caacataacc cattcctgaa
     4501 cgcaaaccgc cgatcatttg gaaaataata tctgcaacac ttcctttata agcaacccga
     4561 ccttcgattc cttctggtac taatttattt gcttcattga cactaccttg gaagtaacgg
     4621 tcttttgaac ctttttccat cgcgcctaat gagcccatac ctcggtatgt tttgaatcga
     4681 cgtccttgga agatttcgaa ttcacctggt gattcatctg tccctgccaa catacttcct
     4741 agcatcactg catgtccgcc ggcagctaat gctttgacga tgtcaccaga atatttgatc
     4801 cctccgtctg caataatcgc tttgccatat tgacgagcaa ctgatgctgc atcataaata
     4861 gctgtgagct gaggtacacc tacaccggct accacacgtg tcgtacaaat cgatcctggt
     4921 ccgataccaa cttttacgac atctacacct gcatcatata aagcttttgt cgcttcagcc
     4981 gtcgcaacgt ttcctgcaat caatgttgca tctgcaaaag ttgaacggat ttcttgaatt
     5041 tttcggatca cacctgcact atgtccatga gctgtatcga tgatgattgc atctgcccct
     5101 gcttctaata aagcattcgc acgctcaaat gtatcgcttg ttacaccaac ggctgctgct
     5161 acaagcaatc gaccatgttc atcttttgct gcatttggaa attcgatcac tttctcgatg
     5221 tctttgatcg tgatcaatcc gcttaaacga ccttcgttat ctacgattgg taatttttcg
     5281 attttatgtt tttgcaaaat cttttctgca tcttttagag aggtacctac tggggcagtc
     5341 actaagttgt cttttgtcat cacatcagca atcggcatgt gataatctgt tacaaaacgc
     5401 atgtcgcggt ttgtaattat ccctaccaat tttctgtttt caagtgtttc aacgattggc
     5461 acaccactga tacgatattt gctcatcaat tcttctgcgt ctgctacaag atgctgtggc
     5521 gttaagaaga acggatcaat gattacgcca ctttcagaac gtttgacttt tcttacttca
     5581 tccgcttgct ggctgatcgt catgttttta tggatcacac ctagtccgcc ttgtcttgcc
     5641 atagcaatgg ccatcttgct gtcggtaaca gtatccatac ttgcactgat gattggaata
     5701 ttcaacttaa tatttttagc taattgtacg ctcatatcca cttcgtttgg taacacgtga
     5761 ctttctgctg gtatcaataa gacatcatca aaagtaaatc cttttttcgt gaactttgtt
     5821 tcccagttgg acatttttag taccactcct ctaatttagt ttatctatta aaataattga
     5881 ttttttcatt taagtcaatg atctacttgg aatcaagtta gctttctcat agaataccaa
     5941 tataaagcgt ttacatctgt gtgtattaaa agagattgta aaaaagctgt cctgcatcaa
     6001 gtaataagaa cagccaatca aaaacagctt ctcatgtttt tgaattggtt gggtttatta
     6061 ccgcagatgc aaacttttga acaccgttta gtggagaggc tgtgaaaaag ctgcttagtt
     6121 tcgagtagta agaaaaattt tgtgaaaatg gctttccaca tttttgcata aattggactt
     6181 aataccgaga aactggcttt tgaacaccgt ttatcgtaaa aagggactgt gacaagactt
     6241 ttgtcacagt cccttactat tatttaacta tggataaaca aaatgaggtt ctttactacc
     6301 cctagatatc tagcaaaata gctgatcttt ttgctagttt atcttcttgg gacggataaa
     6361 cttccaataa tcccgtattt tttcttcaag tagtaacgga ttgctaaagc agttgccccg
     6421 ataatgataa ctactactgg atctaatact ggattgataa ctggtggcaa tagtgttgtc
     6481 gcagaaaaca gtacgaccca aagaagtgtc gttccaccta ggataagcaa tgtcttaccc
     6541 attcctggtt tcttgcttcg atctgctccg ggatattcat attgatagat gtatttgtac
     6601 atcatataaa agacccagcc accgattgca gaacctagaa cgagtgtaga aaagccataa
     6661 gctggcgttg ttccacgtga aaacaatccg gtaatcgcaa tcatgatact taatagacca
     6721 agcaacagca acgtattatc taaccacatc aataaagggg tggatgaatt ttttacttct
     6781 gctggcttat tgatgattgc ttccgttctt tcagagactg tcccaaacaa ttgacgggct
     6841 gttcttccgc ctttttgttc tgcaactaaa gtaggcagaa tgtcatgaag ggcttttact
     6901 ttttcttctt cagacaaatt cgctgcttct aaagattttt tcaaatcaaa aatgtactgt
     6961 tgatttcttt tggttaattt tgtttctaaa ctattgtttt cttttacgat tgctcgtaat
     7021 tgttctggtt ccattatcta atagtcctcc ttagccgttc cttttctcaa cggtcgtcac
     7081 aaaagacatt ctaccatatt ctacagctag tttgatagcc cttttacaca ttaaagcgga
     7141 ataacattac gtcgccgtct tgtacgacat aatcttttcc ttctaatcga acacgtccag
     7201 cttcttttgc tgcatgcatg tttccgtaat gatccaagtc ttcaaaagag acagtttctg
     7261 cacggataaa tccgcgttcg aaatctgaat ggatgattcc tgctgcttgt ggtgctttga
     7321 ttcctttttt gaatgtccaa gcacgtactt cttgttcccc agcagtaaag taagtagcta
     7381 agcctaacaa atcataagca gcacggatca actgatccaa acctgattct tcgattccta
     7441 aagcttctaa aaattccgct ttgtcttctt catctaattc tgcgatttct tcttctgcac
     7501 gagcactgac cacgatcact tctgcatttt cttctgcagc aaagttgcgc acttcttgta
     7561 cataatgatt cgcgtctgca tctgctacgt catcttctga gacattggct acataaagaa
     7621 ttggttttgt cgtcaataaa aatagtgatt taacgatttt ttgttcttct tcagtaaatt
     7681 cgatcgttcg ggcagatttt ccttcttcca gtacaggttt gattttatcc agtacagcta
     7741 gttctgccac tgcatcttta tctttggttt tagcaacttt tgctacacga gtatagcgtt
     7801 tgttgataga ttctaagtct gctaacacta gttccaagtt gatcgtatca atatcttcta
     7861 gtggatcaac acgtccttct acgtgagtaa tattatcatc atcaaaacag cgaacaacgt
     7921 gacaaatagc gtctacttgg cggatatggc ttaagaattg atttcccaaa ccttctcctt
     7981 tacttgcgcc ttttacgatt ccagcaatat ctgtaaattc aaaagtcgtc ggaacagttt
     8041 ttttcggatg tacaagttct gttaagcgtt gcaaacgcca gtcaggtact tctaccatcc
     8101 ctacgttggg gtcgatcgtc gcaaagggat agtttgctgc ttctgctcct gcttttgtga
     8161 tcgcattaaa caaagttgat tttcctacgt tgggcaaccc aacaattcca gcagtcaatg
     8221 ccataaattt attcactctt tctctgcatt tttttcaatt acttttttta atttcttttc
     8281 aaaatctcga cgggtcatca tgacgatatg tccgcaattc atacatctga ttttgatatc
     8341 tgcgcccatt cgaatgactt cccagcgatt cgtctggcaa gcgtgaggtt ttttcatttc
     8401 aacgatatcg tgcaagtcgt acataaaaat agcctccttt ttgtttattc ttcatcaaat
     8461 tgaatattca agatatcaag aattcgagtc aaatcttttt gagaaagata ttcaatctcg
     8521 atcttacctt tcccattttt ttcttggata gctacacttg taccaaattt atccatcaaa
     8581 cgatcttcgc tttctcggat ataatatggt ttttcctttg ctagccttgg gatttttttc
     8641 ttttcttttc catcattttg atttaactca gaaacaagct gttccagttg gcggacagtt
     8701 aaattttcag ttactgcacg attggctaat ttcaagatca atgttttatt ttttaaacct
     8761 aacagcgtac gggcttgtcc catagataaa cgctgatctt gtaccatttc cttgacaaga
     8821 tccggtaaag aaagcaagcg caaataattg gcgatataag gtctgctctt tcctaaacga
     8881 ctagctactt ctgcttgtgt tagtttcagg tttttcatca gcatctcata tgcttctgct
     8941 tcttctaacg gattcagatc ttctcgctgc aagttttcca gcactgctac ttgcatcatc
     9001 gcttcttcgt caaagtctct aacgatagca gggatcgttt ctttttcagc tagtttggac
     9061 gctcgaaaac gtcgctcccc tgcaataatc tcatatcctt ttactgcgga acggcgtacg
     9121 atgatgggtt gaaagacacc tgattgttca atagaattag ctagttcctg caaagatact
     9181 tcttcaaatg ttttacgggg ctgatacgga tttggtcgca gctcattcaa tggtagctgg
     9241 acaacggtat catcttttac atccaccgtc tctaagtttt ctaaatcttg aaacagtgca
     9301 tcgattcctc ggcctaatcc tttacttttc ttcacgactt accacttcct ttgccaatgc
     9361 ttggtagact tcagctcctc gagaacgtgg atcgtagtcg atgatcggtt ttccatgact
     9421 aggtgcttct gataaacgaa tatttcttgg aatgatcgtt tcgtaaactt tttcgcggaa
     9481 gtatttacgt acttcttcta cgacttcatt tcccagattt gttcgtgcat catacattgt
     9541 cagtaagact ccctcgatct ctaattctgg attaaagtgt ttttggacta aacgaaccgt
     9601 attcagtaat tggcttaatc cttccaatgc gtaatactca cactgaacag gtatcaaaat
     9661 cgaatcactt gctgtaaatg aattgattgt cagatggcca agagaaggcg ggcaatcgat
     9721 caaaatataa tcatactgac tgcttacttc tgctaaagat ccttttaatc ttgattctct
     9781 tgccatcatt gacgtcaatt cgatctctgc tcctgctaat tggagagtcg caggcacaat
     9841 actcaaattt tcgtgttcag tgatcaaagt tgcctcatca attggcaatt cattgactag
     9901 aacatcatag atgtctcttg tcacatcagg ttttctgatc ccgacaccac tggtagcatt
     9961 tccttgtgca tccatatcca ctagcaatac ttttttgcca aggctagcaa gacaagcacc
    10021 tagattcacc gtcgtcgttg ttttgccgac gccacctttt tggttcgcaa cagatattat
    10081 ttgtgccatc tcttctcctc ctatttgatt ggctgcttat taggcagtcc gggctttctt
    10141 gggtatttct ttggggttgg tttctttttt tgaataacga tgatatgccg ttgatcagag
    10201 acattcggca aggtaaccgc ctcttctttg aggaatttac cacctaataa agcaatcgct
    10261 tgttttgctt ctgtcaattc ctcttcactt tttgctgctt tcaatgcata aaaatagcct
    10321 tcttgtttag ccaagggcaa acacaattcc gctaacacat tcaaacgagc aaccgcacga
    10381 gcagtgacaa ggtcaaatga tgcacgaaag tgaggatttt gcccaaatgt ttctgcccgg
    10441 tcatgatata aggaagcatc gattcctaat aatcgggtta actcagataa gaaggttatt
    10501 cgtttattca gagaatcaac gatcgttatc tgcagttctg gaaaggcaat ttttaaaggt
    10561 atgctaggaa accctgcccc cgaaccaaca tcgcataaag ataaaggttg cgtaaagtct
    10621 acttcaaatg ctaatgtaag tgaatcgtaa aaatgcttca gatatacgtc tttttcatcc
    10681 gtaatagctg taaggttcat cttttcgttc cattcgacta atgtccgata ataaatagcg
    10741 aattgattca tttgatgatc ggtaagctct atcccttttt ctgccaagga ttggcgaaat
    10801 tcttctggta tcataaatat tcctttcatt gtgaaacagc aattgtttca cagattctct
    10861 ccctacttta acgcaaaatc tctagacatg caatccttcc atatggattc ttaaaaattt
    10921 gaaaagtaag aaaagccgat agactttttc tttctagtat gactcataaa atatacacag
    10981 aagagagaac tagctttgag caatttctgc aaaaactagt tctctcttct atttattatt
    11041 acgtattacg ctggttcact gactttcgca atcttccctt gttcgatata gaccattagg
    11101 atacttaggt ctgcagggtt tacgccactg attcggctag cttgggcaat tgtttctggt
    11161 tggattttct gcaatttttg ttttgcttct gttgctaatc cgttgattgc tgcgtagtcg
    11221 atgttttctg gaatcttttt cgcttccatg cgttttaatt tttctacttt ttccatggct
    11281 tttttgatgt agccttcata tttgatttgg atttctactt gttcgatttc ttttcgtgtc
    11341 aattcttcat tttctggaat aaaccgtaga agttctgcat aagtaatctc aggacgtctt
    11401 aaaaagtcgc ttgctagtac accatctttt aatggtgccg cattaatcgt tgctaaaaag
    11461 tcttggactt cttctgttgg tttgattcgt acattcatca aacgtttgat ttcttgttca
    11521 actgcttctt ttttcttcaa ataattcttg tattgatctt cttttactaa gcctacacgg
    11581 tgacccattt ctgttaatcg caaatctgca ttatcatgac gtaaaagcag acggtattca
    11641 gcacgtgaag tcagcaaacg ataaggttcg ttcgttcctt ttgttaccaa atcatcgatc
    11701 atgacaccga tgtaaccgtc acttcgtttg atcactaaag gttcttttcc ctgaactttc
    11761 aaagctgcat tgataccggc aatcagccct tgtccagccg cttcttcata accgcttgta
    11821 ccatttgttt gtccagctgt ataaagattt tcaacgactt tagtttctaa tgtcggacgg
    11881 agctggtgtg gctctactac gtcatattcg atagcatatc ctgtacgcat catttctact
    11941 ttttctaatc cagcaataga atgaagcatg ttgacttgaa catcctctgg taaagaagta
    12001 gataaacctt gaacatagac ttcttccgta tttaagcctt ctggttccaa aaataattga
    12061 tgacgtggtt tgtctgcaaa acgcacgatc ttatcttcga tggatggaca atagcgagcg
    12121 cctacccctt caacgatccc tgtaaacatt ggggcacgat gtaagttgtc tcgaataatt
    12181 tggtgagtcg tctcacctgt ataggtcagc cagcaagatt cctgatctag tttataggca
    12241 ctatctggtg tgctgaagct aaaatgattc ggctctttgt caccaggctg ctcttctgta
    12301 acagaatagt cgatcgtact tgattttact cgaggcggtg ttcctgtttt gaaccgttcg
    12361 atagcaaagc caagttcttt tagatgattc gctagtccaa tagaaggttg agagttattc
    12421 ggacctgatg aatatttcaa ttcaccgata atgatttctc cgcgaagtgc tgttccggct
    12481 gtaataacaa ctgctttggc ccggtagctc gctcctgtgg acgtcactac tccatgacaa
    12541 acaccatctt cgacgatcag ttcttcgacg attccttgtc ttagcgtcaa atttggttct
    12601 ttttcgatcg tatgtttcat ttctgttgaa taagcatgtt tgtctgcttg tgctcgcaat
    12661 gctcggacag ctgggccttt tcctgtgttc aacatacgca tttggatata ggttttatcg
    12721 atattcttac ccatttctcc gcctaacgca tcgatttctc gaacgacaac gcctttagct
    12781 ggtccgccta cagaaggatt acatggcatg aatgctacca tgtccaaatt tattgtcagt
    12841 aataatgttt ttgatcccat acgtgcagca gcaagtgcag cttctgaacc ggcgtgtcct
    12901 gcgccaacaa cgatcacgtc atacgcatct gcttcataat gttccaatcg tttgttcctc
    12961 cttttatttt cctaaacaaa attgactgaa taattgagtg attagctcat cttgtacact
    13021 gtcgccgaca acttctccta gatagtccca gcaacgcgtc atatctattt gaacgagatc
    13081 cacaggcatt cctgaatcaa tacctgcaat gacttcttca agtgagaggg aagctttttc
    13141 taacaacgcg atatggcggg tattagaaac ataagtagcg tctctttctc ctgtttctcc
    13201 gctgaagaat aaatcagaaa tagctgattc caaacgatct agtccgtcgt ttttagctac
    13261 ggaaattgaa aaaactggtt cattttcgat caatttcttc aatttttctt gttccagctg
    13321 tgctggcaaa tctgttttat ttagaagaat gatccgtttc aatccacttg tcgcttccaa
    13381 taattgttca tcttctgctg tcagtggttc gctttggttt agaacaagta agatcaagtc
    13441 tgcttctgct aatgcttttc ggcttctttc gaccccgatc cgttccacca catcttctgt
    13501 ttcccgaatt ccagctgtat cgattagctt gagcggtacc ccccgaacat tgacatactc
    13561 ttcgattaca tctcgagtcg ttcctgcaat atccgtaacg attgcttttt cttctcttaa
    13621 caaatggttt aacaaacttg atttgccgac atttggccgg ccgatgattg ccgtacttaa
    13681 cccttcccgc agaaccttcc cttgcttgga tgtagcaagt agcgcttgga ttctttgttg
    13741 gatcatctgc gctttttcaa gcaataactt cgtagtcaat tcttcgacat catcatattc
    13801 tggataatca atatttactt ctacttgtgc taatgtctct aaaatctctt gtctcaatga
    13861 gcggatcaaa gcagacagat tgccgtctaa ctgattaaga gctagtccca ttgctttgtc
    13921 tgtttttgcc cgaatcaaat ccatcacagc ttctgcctgt gaaaggtcaa cacgaccatt
    13981 caagaatgct cgttttgtga attcgcctgg ctcagctaat cttgcacctt ctcttaacaa
    14041 tagctgcaaa atttgattga ctacaacgat cccaccgtga caattgattt ctactacatc
    14101 ttcccgcgta aatgtctttg gtgctctcat cacggagacc atgacttcat cgacaagctg
    14161 attgctcttg ggatcaacga tatgtccata atggatcgta tgacttggta cttctgataa
    14221 tcgtttgttt ccagattgat aaactttatc tgctagttgc acagcttgat cgccacttaa
    14281 acgaacgata ctgattgcac cttctccagg tggggtagaa attgccgcaa tcgtatcaaa
    14341 ttctaaagta atttcagcca ttttttcact tcctttttca ttttgcgcac aaaaaaagtg
    14401 cccactccac cctttatgca caataaacgg tgaacttcgc actttgactg cttgttcttg
    14461 attaaattct ggtcatagat tatcacactt gctataagga atcaagtgtt taaaacaatt
    14521 agatgaagtt gagcctgttc tgcttccatt accttatatt taattgtcct tggatgtctc
    14581 tttgcgttct ttggtttatt cgaagagaag atactgtata aacaaggctt tatctttctt
    14641 aaaaaaaacg gtacactaaa tggtagcgct atctaaacta tacacttttg aaaggagaaa
    14701 atatgtgagc ccgttcagat ctgctgcatt ggaagaagaa agtgaccctc ggatcaacga
    14761 tgtcgtttta tctacaggga atatcaacca gaaatatatc gtccgcgata tcgtttttgt
    14821 tgtggaatgc ttagaagctg atttgtttga cccatctttt cccaaagatg accttttctt
    14881 aacaacgaag aggaaattaa agacgaaggt acttgaatat ggtgcgaatg cagtaatcaa
    14941 ctgtcatttt gagtatcagc aaaaaaaacg cgacggaaag tattttctgg aactttttgc
    15001 ttatggaaca gtgatccaat ttatccaaac aacgattggt taaatgaaac agacaaaaaa
    15061 agcggatcaa aactgaagac agtttcgatc cgcttttttc tatcaaagtt agtgactact
    15121 tcatcgtata ctctgataag aatgatttct agtaaaatat acttggtttg aaaaactttg
    15181 tcaacgtgat ttattcaaaa agtaatggaa tcaataatat tttttagcag gttctactac
    15241 taaataacga taaggttcct caccttccga atgtgttttt acatgttcat ctttgcttaa
    15301 tgcagcatgg atttgtttac gttcaaatgc aggcattggt tctaagaaaa caggctgccc
    15361 tgtccgtttt actttttcag ccgtgcgatc agctaaacgc tgaatgatct cttggcgctt
    15421 ttcacggtaa ttgcctacat tgactactac agacagctta tttcttgcta aacgatggat
    15481 gaagacttgt gccagatatt gcaatgcatt cagtgttttt ccatgtttcc caatcagtat
    15541 gccttgcttt tgtgtttcta aatggaaaac aaccatatta tttgattctc tttccatttt
    15601 gacaagagct ggagcatcaa gctgttttga aatttcagta agataaactg ccaattccgt
    15661 taaagctgct tcatcaccta gctcacttac ttcttctgtt ttttcttcaa gaatcgtttc
    15721 gttgactacc tcgatctcag ctgttggttc ttcttccaaa atttcttcta cagtctgttc
    15781 tactgtttca gaaacttttt cgctgatact tggctggatc gaaagccgtg cattctttcg
    15841 acccattcct aggaaacctt tttttccttc ttccagtatt tcgatttcga cttggtcttt
    15901 ggccaaaccc aaatcagcca gacctagttg gacagcttcg tctattgttg cagcttcata
    15961 aatcggcatt agcattacct cccctattat ttccgttttt tcttaggatt cattgctttc
    16021 ttaagagcac gttctctttc gcggattctc cgtgcttctt cttcacgctc ttttcgaatt
    16081 ttgaaagggt tgttgatcag cagcgtttgt acaacttgga aggcattgga aactacccag
    16141 tataatgaaa gaccgctggc taaattgaca cccatcacta aaatcattac aggcatcacg
    16201 aaattcatga tcttcattga tgcattcgat tcaatttgac tcatgctaga taaatacgta
    16261 cttgcaaaag taaagattgc tgctaaaatc ggcaaaataa atgttggatc cgcgttccct
    16321 aagttcaacc ataagaaatg cccttgtttc aactctggta cacgtgaaat agattgccat
    16381 aacgccatca agattggcat ttgtactaat aaaggaagac aaccagcata tggattgacg
    16441 ccattttctg catataaacg ctgctgctct tctcttaact tactttgtgt ttccggatct
    16501 cttgaactat attgttgctg cagtgctttt aatttcggtt gtaattcttg cgttttacgc
    16561 atgctctttg tttggaaatg catcaacggc aataggatca cgcggatgat cagtgtaaat
    16621 aaaatgatcc ctatccctgc attaccaaat gacaacgcct tgatcgcctc agcaaagtaa
    16681 taaacaatat aacgatccca aattcctgta ctctgtgcgc tgacttcccc agttccgcaa
    16741 ccggataaga cgatgaccaa actaacgata ccggccatca aaagtaaacg tttgtatttc
    16801 ttcacttact cttttcctct ctgtcgatta tttttgcaag ttttaagacg tggactaaat
    16861 tggagcgaac ctcatcataa gtcaacccct tcacacttgg tctagcaatc acaataaaat
    16921 ccaactccgg atcaatttct tcttttatag aataaactgc tgctcggatt tttcgtttga
    16981 cttcattgcg gtttaccgcg ttgccgacct tttttcctac agataaacca actcgaaaat
    17041 gaggctgtcc cggtttttcc aaacggtaaa cgacgaattt gcggttagca aaagaatctc
    17101 ccgtatggaa cacggcttga aactctcgtt ctttttttac tcgatacgct tttctcatta
    17161 gttttctttc cttttctatc tctcacttac gctcataatc ataccataat tacgattgtc
    17221 ctttcatcat ttccctaaaa aagagtataa aaaaaaccac tgaaacccca gtggcctaag
    17281 ctgaaagaac ttttcttcct ttgcgacgac ggctagctaa cacacgacgt ccatttttag
    17341 tactcatacg tttacggaat ccgtgaactt tttgacgttt acgtttattt ggttggtatg
    17401 ttcttttcat atattccacc tccaaaatgt tcttatctat tttataaaca cagacatact
    17461 ttgatagtat aacgacaaag tagtgatttt gtcaatataa aatagaagat cgattgttaa
    17521 aacttatcca caagattatt tttttctatg ggaatcctat gtggaaaaag ttatgcacag
    17581 ggattatcca cagataataa aaggctggtt ttacacagaa aacacacgtg taaaaaaagt
    17641 aatccacaat caggcgattt cctgtgtatt ccgtctccta actattggta tatctgtatt
    17701 ttttatccac agacgcaaga ggaaatctat tggtttttac gagttttcca cctgtgcatt
    17761 agtggtgtgg aaaacttttt ttgacaactg tgtttttctc ttttttcttt ttgtcgattg
    17821 tgtggataat tgtaattaaa aaattttttt cttcggtttc tgtggaaaac tattgaaaaa
    17881 aatgctaaat tagtactagt tattcacttt ttaatgaagg aggaggcctt atatggtatc
    17941 cctcgatgct ttatggaatg aattaaaagc aacataccaa aaggatttat cgcctgctag
    18001 ctataataca tggatcgaaa cagcgaaccc tcgaaccctt gatcaaaacc agctcgttgt
    18061 tgaggttcct agcaagattc ataaagaata ttgggaaaaa aacctggcga caaaaatcgt
    18121 tgaagtcggt tatatgttat caggaaatga gattatccct cgctttatta ctggcgaaga
    18181 agcagagcaa gaagaagtta tagaagaaaa aaatccaaaa gttgtggcac ctagtccgct
    18241 aaaaaaagcc atgctgaacc ctaaatatac ctttgatacg tttgtcattg gtaaaggaaa
    18301 ccagatggct catgcagcag cgctcgttgt agcagaagat ccaggttcta tttataaccc
    18361 gctcttcttt tatggaggcg tgggacttgg taagactcac ttgatgcatg caattggtca
    18421 tcaaatgctg caaagtcagc ctaatgccaa agtaaaatat gtaagcagtg aaacttttgc
    18481 taatgatttc atcaattcga tccaaaacaa aacagcagaa gagttccgtc aagaatatcg
    18541 aaatgttgat ttactgctag tggatgacat tcaatttttt gcagaaaaag aagctacgca
    18601 agaagagttt ttccatactt tcaatgcctt gtacaatgaa gggaaacaaa tcgtactaac
    18661 cagtgatcgg ttgccaaacg agattccgaa actgcaagaa cgccttgttt ctcgctttgc
    18721 atgggggctg tctgttgata ttacaccgcc ggatcttgaa acaagaacag cgattttacg
    18781 taaaaaagcg gcggctgaac gtctagagat cccagatgac acactaagct acatcgcagg
    18841 acaaattgat tctaacattc gtgaattaga aggtgcgctt gttcgagtgc aagcttttgc
    18901 tgcgatgaat agtgaagata tttcgactag tctagctgca gacgcactga aaacgttaaa
    18961 atcaggaaaa ggacatcctc aattgtcaat cctgcagatc caagaagaag tggcaaagta
    19021 ttatcacatc caattgaaag atctcaaagg aaagaaacgc gtcaaatcta ttgttgttcc
    19081 tagacaaatc gctatgtatt tggcacgtga gctcacagat aattctttac cgaaaatcgg
    19141 agctgaattc ggtggcaagg atcatacaac ggttatccat gctcatgaaa aaatccagca
    19201 gctgatggat tctagtgtca gtatgcaaaa tgaagtatca gaaatcaaaa actttttact
    19261 aaattaattt gtcgattcta tcaactgaaa atagcatgtg gataaaagaa aaaaacgttc
    19321 aaaagttata cacacttttt ccacagctgt tttttcgttt ctctcttacg ttttttgagt
    19381 tttccacaga atcaacatgc cctattactt ttattattct ttttaactaa taataaataa
    19441 acaaacattc aaaggagata catcatgaaa gttactttaa accgagctag ctttatgcag
    19501 gaattgcaaa ctgttcaacg agctatttca agcaaaacca cgatccctat tttgacaggt
    19561 gtaaaaatca cactgacaca agaaggtttg actttgacgg ggagcaacgc tgatatatca
    19621 attgaaactt ttttgtctgt tgaaaacgaa aaagcaaata tgcaaatcga atctactggt
    19681 tccattgttt tacaagcacg tttctttagc gaaatcattc ggagacttcc tgaagaaaca
    19741 tttactttag aagttttaga aaataaacaa gtagcgatca cttctggaaa agcgaatttt
    19801 atcgtaaatg gattagatgc agataactat cctcatcttc ctgttgtcga aagccataac
    19861 cagatgaaat tacctgtaca cgtattgact aaactaatca acgaaacagt ttttgctgtc
    19921 tcacaacatg agagtcgtcc aatcttgaca ggtgtgcatt tcattttatc tgataattct
    19981 ttattagctg tagctactga ttctcaccgt ctaagtcaac gcgtgattcc agtagaacaa
    20041 gcggctgatc attttgatat tgttattcct ggaaaaagtt tgatcgaatt atctcgctca
    20101 ttaacaaatg aagaagaaat cgtcgaaatc agcattatgg aaaaccaagt gttgttcaaa
    20161 acagaaacga tgtatttcta ttcccgtttg ctagaaggaa actatccaga taccaatcgt
    20221 ttgattcctt caagttttaa tacagaggtt gaattttctg ttcctagctt tttagcggcg
    20281 atcgaacggg cttctttact ttctcatgaa ggccgtaaca acatcgttcg tttatctatt
    20341 cgtccagatg cggttgtttt atacggaaat tcgccagaaa tcgggaaagt agaagaaagc
    20401 ttgagttata cagcaagcag tggcgatcca ttagatattt ctttcaatcc ggattatatg
    20461 aaagcagcgt tgcgtgcatt tggagatatg agcatcaaag tgaaatttat ctctgctatt
    20521 cgtccattta cattggaacc aacggaagat ggcgttcaat ttattcagct gattactcct
    20581 gtacgtacaa attaacaatg attttcaatg ttcttgaaaa tttaattgaa aagaaataga
    20641 aaaaataaaa ttttaaacag aaggccctaa aatctctttt aaggctttct gtttattttt
    20701 gtttaaatca ccttttttag attaaatcgt cttatatgga aaaatatatg gataaatttg
    20761 ttttattgcg aaaaaaaagg tataatagag tatactttta ataatgaaaa tgagggatgg
    20821 gcattgaaac aacaagtcat tctaaatacg gaattcatga cgttgggcca aatgttgaaa
    20881 gaagtcacag ttatcggtag tggcggacaa gcaaaatggt atttggcaga aaacactgtg
    20941 ttagtcgatg gcgaaccaga aaatcgtcgt ggacgcaaac tttatcccgg catgatggtt
    21001 gaagttccag aagtaggaac tttttttatg gtaaaaaaag gaaacgacga taatgaggct
    21061 gaataagctg tatttaaaaa attatcgaaa ttacgaagag ctgaacatcg aattttccaa
    21121 gaacctcgtc atctttttag gagaaaatgc gcaaggaaaa acgaatcttt tggaaagtat
    21181 ctacgtatta gctatgacgc gaagtcatcg gacaagtagt gagcaggaat tgattggctg
    21241 gactgacgat caggcgatga ttcaaggaga gatcacaaaa ggttcatcca ctcttccatt
    21301 agaaatctta ttatctaaaa aaggccgaaa aaccaagatc aaccatatcg aacagaaaaa
    21361 gttaagtact tacgtgggac aaatgaatgt cattttattt gcaccagaag atctttcttt
    21421 agtaaaaggc agcccgcaga tcaggcggaa gtttttagat atggaattag gccagatcaa
    21481 tccaatctat ctttatgatc ttgtccaata ccaagcaatt ttgaaacaaa gaaaccagta
    21541 cttgaagcaa ttgaatgaaa aaaaacaaac tgatttgctt tatttggata ttttgtccga
    21601 acaactagca gcgtttggca gcaaagtatt gaaagcaaga gcacagttcg tcaagcgatt
    21661 ggagttttgg gctaattctt tgcatcagca aatcacccat caaaaagagc agctggaaat
    21721 cgagtatctc accgcagtcg attctttaga aacacatacg caagagcaaa tccaagaaca
    21781 atttctcgca cttttgaacc aaaataaaaa gaaagacctt tttcggggaa caacgacagt
    21841 tggtcctcat cgtgacgatc tttccttttt tattaatcag aaaaatgtgc agacttatgg
    21901 atcgcaagga cagcaaagaa caactgcact aagtgtcaaa ttagcagaaa tcgatttgat
    21961 taaagaagag acaggggaat atccaatcct tttgttagat gatgtgatga gcgagctgga
    22021 tgataatcgt caactccatc tgctagaaac aatcgaagga aaagttcaaa cgttcttaac
    22081 aacaacgaca cttgaccatg taaaaaataa aatgactgtt gaacctgaga ttttttatgt
    22141 tcaacaaggg aaactaaaag gagaagaaac tgaatgacag aagaaagaag tttagtagaa
    22201 cgcgctaaag agtatgatgc cagtcagatt caagtacttg aaggacttga agccgttcgt
    22261 aaacgacctg gcatgtatat cggttcgact agttctgagg gtctgcatca ccttgtttgg
    22321 gaaattgtcg ataattcgat cgatgaagta ttagcaggtt ttgcaacgaa aatccatgtg
    22381 attattgaaa aagacaacag tatcaccgtt attgacgacg gtcgggggat acctgtagat
    22441 atccaggcaa aaactggacg tcctgcagtt gaaacggtct ttactgtttt acatgctgga
    22501 ggaaaattcg gcggtggtgg gtacaaagtt tctggtggac ttcacggagt aggatcttct
    22561 gttgtaaacg cgctttctac acagcttgat gtcaaagtat acaaagaagg aaatgtgtac
    22621 tatcaagaat atcgtcgtgg agctgtagtg gacgacttaa agattatcga acaaacggat
    22681 cgccatggaa caacggttca ctttacgcca gaccctgaaa tttttacaga gacaactgag
    22741 tttgattttt caaaattggc tacccggatc cgtgaacttg ctttcttgaa ccgcgggatg
    22801 cgtatatcga ttgaagacaa acgagaagaa gaaccagtca tcaatgaata ccattatgac
    22861 ggcgggatca aaagttatgt cgaatacttg aatgcaaaca aaaccgtgat ttttccagaa
    22921 cctgtatatt tggaaggtga acagcaagat atcgcagttg aagtctctat gcaatataca
    22981 gacggctacc attccaatat catgagtttt gccaacaata tccatacgta tgaaggtgga
    23041 acacatgaat caggattcaa gactgcttta actcgtgtga taaatgatta tgcccgaaaa
    23101 caaaagctga tgaaagaaaa tgacgacaac ttgaccggtg aagacgtgcg agaaggattg
    23161 acagctgtta tttctatcaa gcatcctgac cctcaattcg aaggacaaac aaaaacaaaa
    23221 ttgggcaatt ccgaagtacg gacagtcact gatcggttat ttagcgaaca tttcatgaaa
    23281 ttcttgctgg aaaacccaag tgtgggccgg caaattgttg aaaaaggatt actagcttcc
    23341 agagctcgtc tagcagcgaa acgtgcgcgt gaagtaacga gacgtaaagg tgctttagag
    23401 attagtaatc tgccaggaaa attagcggac tgctctagca acgatcctga aaaatgcgaa
    23461 ttgttcatcg tcgaaggaga ttcggccggc ggatcagcta agcaaggtcg taatcgagag
    23521 tttcaagcca tcttgcctat tcgtgggaaa atcttgaatg ttgaaaaagc aagcatggac
    23581 aagatcttgg caaatgaaga gatccggtct ttatttactg ctatgggtac agggtttgga
    23641 gaagattttg atgtatcgaa agctcgctac cacaaattag ttatcatgac tgatgccgat
    23701 gtcgacggcg cgcatatccg tacattgctg ctgactcttt tttatcgtta catgcgtcct
    23761 attgttgaag ctggatacgt ctatattgct cagccacctt tatacggggt aaaacaaggg
    23821 aagaatatta cgtatgtaca accaggaaaa aatgcagaag aagagttgaa acaagtcgtt
    23881 gcttcacttc ctgcctcacc aaaaccaagc gttcagcgtt ataaaggact tggagaaatg
    23941 gatgatcatc aactatggga aacaactatg gacccaagca atcggatgat ggcccgcgtc
    24001 agtgtggacg atgctattgc agcagatcag atatttgaaa tgttgatggg ggatcgagta
    24061 gaaccccgtc gtgcattcat cgaggaaaat gcacactatg tgaagaactt agatatttaa
    24121 tcatgaagga ggaaaaagaa tgagtgaaga aatcagagaa aacatccatg atgtcaatct
    24181 aaccagcgaa atgaaagact ccttcatcga ttatgcgatg agtgttattg tcgcacgtgc
    24241 acttcctgat gtcagagatg gtctgaaacc cgttcatcgc cgtattttat acggcatgaa
    24301 cgaattaggt gtaacaccgg ataaagccca taaaaaatct gccagaatcg tcggagatgt
    24361 catgggtaaa taccatcctc atggagacat tgcgatctat gagtcaatgg tacggatggc
    24421 acagccattc agctaccgtt atatgctagt ggatggtcat ggaaactttg gttctgttga
    24481 cggtgacggt gccgccgcta tgcgttatac cgaagcacgg atgagcaaaa tcgctacaga
    24541 aatgctgcgt gatatcaata agaacactgt tgatttccaa agcaactatg atgatacaga
    24601 aaaagaacca gttgtactac ctgctcgctt cccgaatctt ttagtgaacg gaacaacggg
    24661 gatcgccgta ggtatggcca cgaatatccc acctcataac ttgtctgagg tagtagcggc
    24721 tatcgatttg ctgatggata atcctgatgt gacgaccaat gaattgatgg aagtattacc
    24781 tggaccagat tttccaacag gtggtttggt tatggggaaa tcaggaatcc gaagagcgta
    24841 tgaaacaggt aagggttcta ttaccgtacg tgcaaaagtt gagattactg agatgccaaa
    24901 tggtaaagaa cggatcatcg tgacagaatt gccttatatg gtcaataaag caaaattgat
    24961 cgaacggatt tctgaactgc acagagacaa gcgtatcgaa gggatcacag atttgcggga
    25021 cgaatcttcc cgtgaaggta tgcggatcgt cattgacatc cgtcgtgacg ccagcgcatc
    25081 cgttatcttg aataacttat ataaattgac atccttgcaa aattcatttg gattcaatat
    25141 gttggcgatc gaaaaaggtg tgccgaaagt tttgagcttg aaacaaatcc ttgaaaacta
    25201 tatcgaacat caacgcgaag tcatcacacg acggacggtc tttgaaaaag aaaaagcaga
    25261 agcaagagca cacatcttag aaggtttgcg tattgctttg gatcatatcg atgaaatcat
    25321 tgcgattatc cgcgggtcta aatcagatga cgaggcaaaa gcaacaatga tcgaacggtt
    25381 cgatttatcc gatcgccagt ctcaagctat tttagatatg cgtttacgcc gattgaccgg
    25441 tttggaacgg gaaaaaatcg aaaatgaata ccaagaactc ttaaaactga ttgaagattt
    25501 aactgacatt ctggcaagac cagaacgtgt tacagaaatc atcaagaatg aattagcaga
    25561 cttgaatcaa cgatttggtg ataaacgacg cacagaatta ctagtcggtg aggtcttaag
    25621 tctggaagat gaagatttaa tcgaagaaga agaaatcgtt attacattga caaacaatgg
    25681 ttacatcaaa cgtttggcaa ataatgaatt cagagctcaa cgaaggggtg gacgtggtgt
    25741 ccaaggaatg ggtatccaca atgacgactt cgtcaaaaat ctggtttctt gttctaccca
    25801 tgatacattg ttattcttta cgaataacgg aaaagtgtat cgggcaaaag gatacgaaat
    25861 tccagaatac gggcgtacag ccaaaggaat cccaatcatc aatttactag gtatcgattc
    25921 gagtgaaagc atccaggcaa tcattgcggt gacgggagaa gcagaagaag gccactatct
    25981 cttctttacg acgcgtcaag gtacagtaaa acgtacttct gtcactgctt ttgctaacat
    26041 ccgaagtaat ggtctgatcg caattggttt gaaagaagac gatgagctcg tcaatgtgct
    26101 actgacagat ggtcaatcta atatcattat tggaacacat aacggctact ctgtcacttt
    26161 caaagaagaa gcagtccgcg atatgggacg tacagcttcc ggggtcagag ggatacgcct
    26221 gcgtgaggaa gattatgtcg ttggggcagc cttaatgaag gaaaatcaag aagtattagt
    26281 gatcacagaa aaaggttacg gaaaacggac aaaagtatcg gaatatccag tgaaaggccg
    26341 cggaggtaaa gggatcaaaa cggcgaacat cactgaaaaa aatggtccac tagctggatt
    26401 gaccactgtt tctggagatg aagacatcat gctgattaca gataaaggtg tcattatccg
    26461 tttcaacgta tcgactgttt ctcaaactgg acgttcaaca ttaggcgtac gtttgatgaa
    26521 gatggaagct gatacgaaag ttgtcacgat ggcagcagtc gaaccagaag ctgcagaaca
    26581 aacagttgaa gaacaaggat cagaagaata accatcaaga ctaagtgtgt aagctagcaa
    26641 gaataaccga ttaaaaaatc tggttattcc tgctggcttt tttgattagt tgaatttctc
    26701 ttaaaatatt cgaaactgtt cattctgtat tgcttttgac caaaatagag tgtataatta
    26761 gagcttgtga gtagtctaat taattagata actctccttg ctcttaggaa cctaagagcc
    26821 gaaagtccac agggaggtga atatcaatgg aaaacacgaa atatgaaatc atgtacatta
    26881 ttcgtccaaa cattgatgaa gaagcaaaaa ctgctttaat cgaacgtttc gatgcaatct
    26941 tgaaagataa cggagcagaa gttatcgaat caaaagattg ggaaaaacgc cgtttcgctt
    27001 atgaaatgaa cggttaccgt gaaggtatct atcacatcgt taaagtatct tctccatcat
    27061 cagcaaatgc tgtcaatgaa tttgaccgtc ttgctaaaat caacgacgat atcattcgtc
    27121 acatgattgt taaagaagaa gcttaattgt tgtttcatgt gaaacaatag aaaacgatga
    27181 gaggagatga ctattttgat taataatgtt gtattagttg gacgtctgac gaaagatcca
    27241 gatttgcgtt acacagcaag tggtacggca gtcgcaacat ttactttggc tgtgaatcgt
    27301 aattttacaa accaaagcgg caatcgcgag gctgatttta tcaactgtgt gatttggcgc
    27361 aaatcagcag aaactttagc aaactatgct cgtaaaggaa cacttttagg tgttactgga
    27421 cgtatccaaa ctcgttctta tgataatcag caaggacaac gtgtatacgt gacagaagta
    27481 gtagctgaca acttccaatt gctggaaagt cgttctgcat ctgaaaatcg ccaacaaagc
    27541 ggcggattcc aaagttctgg tcaatcagct ggcggatttg gcggaaacaa taactctaat
    27601 caaacatctc aatcatccaa cggtatgcct gatttcgacc gtgatacttc tgacccattc
    27661 ggctcaagtt caacgatcga catttcagac gatgatttac cattctaaac gaatttgata
    27721 ggagggaaat agaatggcac aacaaagaag aggcggacgt aaacgtcgta aagtagacta
    27781 cattgctgct aaccatattg aatatatcga ttataaagat atcgaattac taaaaagatt
    27841 tatttcagaa cgcggtaaaa tcttgccacg tcgtgtaact ggtacaggcg ctaaaaacca
    27901 acgtaaaatt actgttgcaa tcaaacgcgc tcgtatcatg ggcttgctac ctttcgttag
    27961 cgaagactaa taaatcctag gaattgaatg actgatcctt ttgatcagct attcaattcc
    28021 tttttttctg taaaaataac ctctattcgt ttagtcgctc gaatgacgaa agttatggta
    28081 aaatcaaatt agtcatatat gggaggaaaa ttatggaaaa taaaaacaat catttatccc
    28141 cgaaacctct cttccttatc ctgtttatat taatcgaagt attggtagtc ttaattttac
    28201 catttcgttt tgttagcgct tcggtcattc tattgatgaa tttatggggt gttcgctatt
    28261 ggttgaaaat gaaacgttgg cttattttaa ataaacgtga aaaaatccag caggcttcga
    28321 ctgtagctga aaccaatcta gcttatgtct cagaagtcat gcctgtagga gtgattgctt
    28381 atcagccatc aagccaaaaa atcgaatggc tcaatccatt agcattgaaa atcaaagatc
    28441 aaagtggatt aacagaggaa gaattgctag atactttttt tactgcaaaa gaaaaaaaga
    28501 aaaaccaagt ctatctagca gataaaacat ttcagtttga tatggataca gtaaagggtg
    28561 ttgtttattt taatgatatt acccaaaacc agttgttaaa actccatcag acgaacagtc
    28621 agccggtgat tggtatttta tctattgata actatgcaga tgccattgat aaattagatg
    28681 acaaagagat ttcttatttg aactctttcg tcactacact agtttctgac tggatgaatg
    28741 aataccatgt ctttttcaaa agaatcaacg cagaacggtt tttcttcgta gcacagatga
    28801 tcgatctgaa aaagatgatg gataaaaaat ttgatttgct ggatcgcttt cgagcagaag
    28861 ctgaaaaaca gagctcgcct atcaccctta gtatggggat tgcttatggc tcaagaaccc
    28921 tcgatgaaat cggtggagaa gctcagaata atttagatgt tgctttagtc cgtggaggcg
    28981 accaagttgt cgtgaaagag gtaaaagaag gagcaaaacc tgtttattat ggggggaaat
    29041 ctgctaagaa tgtcaaacgc acgcgtgttc gttctcgagc gatgagtacc gctttgcgtc
    29101 ggatttttga tgaaacaggc gatgtgttta tcatggggca caagtttccg gatatggatg
    29161 ctttaggctc tgcttttggt gtcagttgtc tggcacgctt caaccagaaa aaagcttaca
    29221 tcgttatcaa tgagaacgag atcattccag atgtagaacg gtgtcttgaa gaaatccata
    29281 agcatcctga attagaaatg caactaatct ctccagaacg tgccatagag ctgaaaaaag
    29341 aagaggacct cctcgtgatg gtggattacc ataaaccttc tctatcgatc tctcagggcc
    29401 tatatgagca atttgataag attgtgatca ttgatcacca tcgtcgtggg gaagagtttc
    29461 caagtaaacc tctgctgact tatattgaat cttcagcttc ttcagcttca gagctagttt
    29521 ctgagctgat ccaataccaa agcagcaaaa caaatcgctt agatcgtttt gaggccacat
    29581 tattgcttgc agggatggtt gtagatacaa atagtttcaa tgtccgtaca actgcacgaa
    29641 cttttgacgt tgccagctat ttaaggtctt gtggagcaga cgcatcctta gtacaatatt
    29701 tattgagctc ggatttagcg acatacttgg agatcagcaa tttgattgct ggaagcgact
    29761 atgtgacttc tgatattgtt gtggcggcag ggacagacga aaaagagtat aatagtgtta
    29821 tagcagcaaa aacagcagat acattgcttt cgatgatcaa tatcaatgca gctttcgtca
    29881 ttacaaagcg gacagacggc ttgattggga tcagtgccag aagtaccggc acgatcaacg
    29941 tccaaatcat catggaatcc ttaggtggcg gaggacactt cacaaacgca gctactcaac
    30001 tggaaaatac gacagttgag gaaacaaaac agaagctatt tgctgcaatc aaagaaaata
    30061 tgaatcaaat atatgataag gagtaatcca aatgaaagta atttttttac aagatgtaaa
    30121 aggaaaaggt aaaaaagggg acatcaaaga agttccagca ggttatgcac aaaattatct
    30181 aatcaaaaat aacttggcaa aagaagcaac gaaaagcagt atcagtcagt tagcaggaca
    30241 aaagaaagca caagaaaaac acgaagctga aatcttggaa gaagctaaaa agttaaaaga
    30301 attcttggaa aaagaagata ctgtagtcga attgaaggcg aaagcagggg aagacagccg
    30361 tttgtttggt tcgatccctt caaaacaaat tgctgaaggg ttaaacaaac aatacaaaat
    30421 caaattagat aaacgaaaaa tcgaattaga aaatccgatc cgttcactag gctacacaaa
    30481 cgtacctgtt aagcttcatc atgaggtgac ggctacgatc aaagttcatg tcgtacaaga
    30541 ataacaaatc ttgatagcga tgttcagctg gtaagtataa ccagaaggaa aaaagacaaa
    30601 ccgaaattta tctgagaaaa cagctgcagc aatgaaagca aaagctgcaa atcgatttca
    30661 gattgatttc ggtttctttt ttgggaacag caaaatagca taaagaaaac gagtataata
    30721 aaagagaact atttttttat tacactttcg gtacgaatga tgacttttct ctcattttct
    30781 tgtaaaatga agcaattgaa gacaaggagc gatacgtatg aatgaagtgt ggcaggatcg
    30841 aatcccaccg caaaatattg aagctgaaca agcggtttta ggctctgttt ttcttgacgc
    30901 agaaacgatc attgatgcca tggagtacat agagccaaaa gacttttatc gtcgtggcca
    30961 tcaaattatt tttgagacaa tgatcgagtt aaatgatcgt aatgaagcga ttgacgtggt
    31021 tactgtcaaa gaccggctgg aacaagccaa tttgttagaa gatgccggtg gtttaagtta
    31081 tctctcagac ttggcattag cagttccgac agcagcaaat atcgtctact atgcgaaaat
    31141 cgttgaagaa aaatcattgc tgcgtacatt gatccagaca gcaacaggaa tcgttacgaa
    31201 aggattcgag caaggagaag aagttcaaac aattttagat gatgccgaac gcagtatctt
    31261 ggaggtttcg gaaaaaagaa atcgaagcgg ctttttatct attgctgaag tactgaactc
    31321 cacgattgaa aatatcgatc gactagctca aaacaatgaa gaaatcacag gtctaccaac
    31381 tggctatcaa ggtctggata aaatgacagc aggtttccag cccgaagaac taatcattct
    31441 tgctgcacgt ccagcggtag gtaaaacagc gtttgcattg aatattgctc aaaatgtagg
    31501 aacaaaaaca gatcgttctg ttgcgatatt tagtttggaa atgggggcag aatctcttgt
    31561 aaatcggatg ctttgtgcag aaggttcgat tgaggccagc catttacgta caggtcagct
    31621 ttcggaagaa gaatggtcga atctgatcgt tgcgatgggg agtctttctc gagcaaatat
    31681 ttttatcgat gatacaccag ggatcaaaat ctctgaaatc cgtgcgaaat gtcggaaact
    31741 agcgcaagaa aaaggcaatc taggcttgat attgatcgat tatttgcagt tgattgaagg
    31801 taacggtaaa gagaaccgtc aacaagaagt atcagatatc tctcgccaac tgaaaaaact
    31861 ggcgaaagag ctgaaagtac ctgtcattgc tctttcacag ttatctcgtg gagtagaaca
    31921 gcgacaagac aaacgaccag tgctaagtga tattcgtgaa tccggatcaa ttgaacaaga
    31981 tgcggacatc gtagccttct tgtatcgaga tgattattat gaaagagaag gcggagatga
    32041 cgatgatgga aacgagccaa aaaatgacaa cgtcatcgaa gtcatcatcg agaagaaccg
    32101 aagcggtgca cgaggaacag ttgaactact gtttatcaaa gaatacaata agttttcgtc
    32161 gctttcgcca agagaagaat tttaaagaag aggttgtgag ccttgagcaa tcccgagagc
    32221 tctcgtaaga agatgcaagg agtaaccgca ggaacgacta gagtacttaa tttaaacaga
    32281 tctccaaagg gattgtgaca aaagtcttgt cacagtccct ttttccgaat aaacggtgtt
    32341 caatcagctg acccttggta ttagctcagc aaacgtcaaa atatgaggaa ctattttgac
    32401 gtttgtttct ctaatactca ggtcaaaacg ctgatcttac gacctctttt ccttaaacgg
    32461 tgttctcctg ccaactcctc ggtcacaagt cacaatatca tcaaacatga gaagcagttt
    32521 tttgaaattg ctccttgtga ctcagagtta aacggcaggc tcacaacctc tttcttaaac
    32581 ggtgttcaaa agcttgcatc tgcggtaata cgcccaatca aacgaaaaat atgagaagct
    32641 atttttgttt ggctgttctt attacttgat gcaggacagc tttttcacaa cctctgattc
    32701 acggtgttcc aaaagtagct tcttcgaaaa ataagtcgaa atttcacaaa aatttgagaa
    32761 gcaattttcg tacattcctt cttatttctt gaagctgacc acttctgtta caacctcttt
    32821 tttaataacc attctaaaaa gataaagttc gttttttaag cgtttttata aaataaaaat
    32881 aaaaatcatt cgattttatt tgaaatatgt atctattatt gatacaatgg ttcaggatta
    32941 aataatatag aacgaggtgt tcacatgtca tctgtagtag tagtaggtac gcaatggggc
    33001 gatgaaggga aaggaaaaat cacagacttt ctcagtgaaa atgctgaagt gattgcacgg
    33061 taccaaggtg gcgacaatgc agggcacaca attaagttta acggtgtgac ttataaactg
    33121 catttgattc cttctgggat tttttataaa gacaagatca gtgtgatcgg aaacggcgtt
    33181 gtagtcaatc ctaaatcatt ggttaaagaa ttagcttatt tacatgaaaa aggtgtagaa
    33241 acaagtaatt tgcgtatttc tgaccgcgcg cacgtaatct tgccttatca tatcaaattg
    33301 gaccaattac aagaagatgc taagggcgaa aataagattg gtacaacgat taaaggaatc
    33361 ggacctgcct atatggataa agcagctcgt gtaggtatcc gtattgcaga cttattagat
    33421 aaagaaattt ttgaagaacg tcttcgtttg aatctagatg acaaaaaccg tcaatttgta
    33481 aaaatgtttg attcagaacc acttgatttt gacgatattt ttgaagaata ttatgaatac
    33541 ggacaacaaa tcaaacaata cgtcacagat acttccgtta tcttgaatga tgctttggat
    33601 gcaggcaaac gcgtgttgtt tgaaggcgca caaggtgtaa tgctggatat cgaccaggga
    33661 acttatcctt ttgttacttc ttctaaccca gtagccggtg gggtaacaat cggaagcggt
    33721 gtagggcctt caaaaatcaa taaagttgtc ggcgtctgca aagcctatac gtcacgtgtc
    33781 ggtgatggac catttccaac tgaattattt gatgaaacag gagaacaaat ccgcgaagta
    33841 ggacgagaat acggtacgac aactggtcgt ccgcgtcgtg taggctggtt tgattctgta
    33901 gttatgcgcc attctaaacg agtttcaggt attaccaacc tatctttaaa ctcgatcgat
    33961 gtattaagtg gattggaaac agtaaaaatt tgtacggctt atgaattaga tggcgaacta
    34021 atctaccact atccagcaag cttgaaagag ttgaaccgct gcaaaccaat ctatgaagaa
    34081 ttgccaggct ggtcagaaga cattacagga tgcaaaacac ttgcagaact gccagaaaac
    34141 gcacgtaact atgtacgtcg tatctcagag cttgttggtg tacgtatctc aacattttct
    34201 gtcggacctg atagaacaca aacaaacatc ttagaaagcg tctgggcgca aatctaagga
    34261 taaaaacgac gactgaatca ggacgttctt accagagcga gtcgaagtgt ttatctatac
    34321 gataataata acttgaagag gtagtgaaag agacgtttag ccttattgcc gataggctgt
    34381 ctcttgaaca ctgtttattc agaataaggg actgtgacaa aa
//
LOCUS       DAFLWC010000022        33261 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.022, whole genome shotgun sequence.
ACCESSION   DAFLWC010000022 DAFLWC010000000
VERSION     DAFLWC010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33261
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.022"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(42..230)
                     /locus_tag="L1V17_000982"
     CDS             complement(42..230)
                     /locus_tag="L1V17_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBN1235766.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            500..862
                     /locus_tag="L1V17_000983"
     CDS             500..862
                     /locus_tag="L1V17_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBN1235767.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            914..2596
                     /locus_tag="L1V17_000984"
     CDS             914..2596
                     /locus_tag="L1V17_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBN1235768.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKETPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            2713..4749
                     /gene="recG"
                     /locus_tag="L1V17_000985"
     CDS             2713..4749
                     /gene="recG"
                     /locus_tag="L1V17_000985"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBN1235769.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKEFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LLTGSTKAKERRELLEKLEQGEINIVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            4798..5799
                     /gene="plsX"
                     /locus_tag="L1V17_000986"
     CDS             4798..5799
                     /gene="plsX"
                     /locus_tag="L1V17_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBN1235770.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            5921..6163
                     /gene="acpP"
                     /locus_tag="L1V17_000987"
     CDS             5921..6163
                     /gene="acpP"
                     /locus_tag="L1V17_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBN1235771.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            6431..7435
                     /locus_tag="L1V17_000988"
     CDS             6431..7435
                     /locus_tag="L1V17_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1235772.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            7436..8380
                     /locus_tag="L1V17_000989"
     CDS             7436..8380
                     /locus_tag="L1V17_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1235773.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            8380..9342
                     /locus_tag="L1V17_000990"
     CDS             8380..9342
                     /locus_tag="L1V17_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1235774.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            9369..10283
                     /locus_tag="L1V17_000991"
     CDS             9369..10283
                     /locus_tag="L1V17_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1235775.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            10309..12090
                     /locus_tag="L1V17_000992"
     CDS             10309..12090
                     /locus_tag="L1V17_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1235776.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            12438..13124
                     /locus_tag="L1V17_000993"
     CDS             12438..13124
                     /locus_tag="L1V17_000993"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBN1235777.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            13144..16725
                     /gene="smc"
                     /locus_tag="L1V17_000994"
     CDS             13144..16725
                     /gene="smc"
                     /locus_tag="L1V17_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBN1235778.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            16734..17543
                     /locus_tag="L1V17_000995"
     CDS             16734..17543
                     /locus_tag="L1V17_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1235779.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            17554..18552
                     /gene="ftsY"
                     /locus_tag="L1V17_000996"
     CDS             17554..18552
                     /gene="ftsY"
                     /locus_tag="L1V17_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBN1235780.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            18739..21006
                     /gene="gshAB"
                     /locus_tag="L1V17_000997"
     CDS             18739..21006
                     /gene="gshAB"
                     /locus_tag="L1V17_000997"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HBN1235781.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKKYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(21095..21547)
                     /locus_tag="L1V17_000998"
     CDS             complement(21095..21547)
                     /locus_tag="L1V17_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HBN1235782.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            21697..22647
                     /locus_tag="L1V17_000999"
     CDS             21697..22647
                     /locus_tag="L1V17_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBN1235783.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            22640..23599
                     /locus_tag="L1V17_001000"
     CDS             22640..23599
                     /locus_tag="L1V17_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBN1235784.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            23596..24351
                     /locus_tag="L1V17_001001"
     CDS             23596..24351
                     /locus_tag="L1V17_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1235785.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            24374..25327
                     /locus_tag="L1V17_001002"
     CDS             24374..25327
                     /locus_tag="L1V17_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1235786.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(25971..26267)
                     /locus_tag="L1V17_001003"
     CDS             complement(25971..26267)
                     /locus_tag="L1V17_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HBN1235787.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            26622..26978
                     /locus_tag="L1V17_001004"
     CDS             26622..26978
                     /locus_tag="L1V17_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBN1235788.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            26988..27887
                     /locus_tag="L1V17_001005"
     CDS             26988..27887
                     /locus_tag="L1V17_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HBN1235789.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            28404..29135
                     /locus_tag="L1V17_001006"
     CDS             28404..29135
                     /locus_tag="L1V17_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBN1235790.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            29280..31307
                     /locus_tag="L1V17_001007"
     CDS             29280..31307
                     /locus_tag="L1V17_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBN1235791.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRINIPVENQRIGTFEGKLSWILADVPGN"
     gene            31415..32512
                     /locus_tag="L1V17_001008"
     CDS             31415..32512
                     /locus_tag="L1V17_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBN1235792.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            32819..>33261
                     /locus_tag="L1V17_001009"
     CDS             32819..>33261
                     /locus_tag="L1V17_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1235793.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKR"
BASE COUNT        11139 a         5762 c         7122 g         9238 t
ORIGIN      
        1 aaaaaaccgt tcactatctg aacggtccaa gtatcattca attaaacgcg ttcaactttt
       61 cctgatttca aagcacgagt tgacacccaa acttttttag gttttccgtc gaccataacg
      121 cgaacttttt gtaagttagg tttaacagta cgttttgttg agttcatagc gtgtgaacgg
      181 ttgtttccac tttttgtctt gcgacctgta aagtaacaaa cttttgccat ggtaatttcc
      241 tcctttgcct tgatttggag caatagaata attcagctca taccagacta acatatcata
      301 tagaatggaa atttgcaagt acattttcat agatacaatt gacaattgag aagaataatt
      361 gtaaattaaa caaggttata cctgaaattt tgcaaggttt ttgagtactt tgggtaactg
      421 ccttttattt caagttgcgc tatgataaaa tatgatagaa gaaaaatggg agttttttac
      481 ccgttaagga ggctcattca tggctgtaaa aattcaaacg tcagctggaa ccattgaaat
      541 taccaatgat gtaattgcaa cagttgttgg tggcgccgcg acagatgtgt tcggtgttgt
      601 aggaatggcc agcaaaaatc aaattaaaga taatattact gagattttgc gtaaagaaaa
      661 ttactcaaga ggagtagttg tccgccaaga agataatggt attgctgtag atgtttatac
      721 gattatcagc tatggtacga aaatctctga agtttcccgc aacgtccaag aaaaagtgaa
      781 atacaatcta gaggcattat taggcgtaac tgccaattca gttaatgtct ttgtacaagg
      841 tgttcgtgta ctgccagact aggcaggaga ctggctggta actcagcagt cgatctgaag
      901 gaggattatc taggtgagtg taacagaaat aagtgcaagc cagttccagg aaatggtcca
      961 ggcaggtgcg aatcgtctgc aagtaaatgc agaatacgtc aattcattaa atgtattccc
     1021 tgtgccagat ggcgatacgg gaacaaatat gaatctatct atgactagtg gagctaaggc
     1081 agtagtagat tcaacctcag aaaaagtagg agaattagca gcaatgcttt caaaaggatt
     1141 gctgatgggt gcgcgcggaa attccggcgt tattttgtct caattgtttc gtggattttc
     1201 taagcaaatt ccagatgttg tctcattaaa tgcttccgat cttgctgcag ccttcactca
     1261 tggagttgaa actgcgtata aagcagtaat gaaaccagta gaaggaacga ttttgacagt
     1321 agctagagaa gcagcgaaag ctggagaaaa gaaagcaaaa agtactgatg atgtcgttga
     1381 agtaatgaca gctgttgtaa aaggggcaaa gcgtgcttta gctaaaactc cagacttgct
     1441 tccagtccta aaagaagtcg gtgtcgtaga cagtggaggg caaggactgc tgtttgttta
     1501 tgagggcttt ttaagtgcat tgaatggaga attccaagcg gatgaaacat atgaaccttc
     1561 tccagcagaa atggatgata tggtcaatgc agaacatcat cgcagtgtcc aaggtcaaat
     1621 ggcgacagaa gatatccatt ttggttactg tacagaaatc atggtaaaaa tcggagaagg
     1681 acctacagtc gatagtacat tcgattacga agaattccgt aactatttag atggtatagg
     1741 agattcttta cttgtggtca atgatgacga gatcatcaaa gtccacgtgc atacagaaaa
     1801 cccaggagaa gtcttgaatt atggacaaaa attcggttca ttagtcaaaa tcaaagtcga
     1861 caacatgcgc ttgcagcatg agacgatttt ggaacacgat gaagaagtga acgagtttgc
     1921 gaaaaaagaa acaccacgta tcccgtatgg tatcgtagcg atcgctgctg gtaaaggcgt
     1981 ccaagagctg tttgaaagtt taggcgctaa ttatgttatc agtggtgggc aaacaatgaa
     2041 tccaagtacg gaagacattg ttaaagcgat tcaagaagta aacgcagata aagtgattgt
     2101 cttgccaaac aataagaaca tcttcatggc agctgatcaa gcagcagaag tagcagatat
     2161 cccagtagca gttgttcctt caagaacgat ttcccaagga ttgacagcta tgctttcatt
     2221 caatgatcaa gcttctttag aagaaaacaa agaaacgatg acagaaatgt tgtctagcgt
     2281 tgtgagcggt caagtcactc acgcgatcag agatacctca attgacggtg tagagatcaa
     2341 agaaggagac tttttgggca tgatcgatgg aaaaatcctg atctctaacc cagatatcac
     2401 agcaacagcg ttaagtacac tagaacaaat gatcaatgag gacacagaga tcgtaacgat
     2461 cttggcaggt gatgaaggaa cagttgaaca agcaaatgaa tttgctgaga aactaacaga
     2521 aaaacatcct gatttggaaa tcgagatcca ccaaggagat cagcctgtct atccttatct
     2581 attttctgct gaataatttc tgtgtcagaa tatctttcta acacagtatt cattcataaa
     2641 aggccttcgg ttagtgatca ggtatgatcg ctgaccaagt cctttttttg ttaagggagg
     2701 gaggaaaaat ttatgcgttc tttagatgat ccaatcacta tgctggcagg agtcggagaa
     2761 aaaagagcag ctagtcttgc cagcttgggc atccaaacga ttgaagactt actgacttat
     2821 tatcctttcc gctacgaaga tattcaggaa agaaatctaa acgagatcca agatcaagaa
     2881 aaggttactt tgaaaggaat cgtagtctcg cctcctgtga tgaatcgatt tggttataaa
     2941 aaaagccgat tgcaatttcg tatgatgcaa gaacatgatg tgttcaacgt ttcttttttt
     3001 aatcaacctt atctaaaaga aaaagtcatt ttatcggagg aaatcgccgt atacggtaaa
     3061 tgggatgcaa agcgtaaagc attgaacggg atgaagattt taggttctca aacaatggat
     3121 gacttttcgc cgatatatca cgtcaacaaa tcaattcgtc aaacgacatt agttgatcta
     3181 atcaaaaaag ggtttcaaga atacggcaca ttgattgaag aaaatctgcc aaacaacctt
     3241 gtggagaaat atcgactgct tgaccgagct tctgctgtaa gaagtatgca ttttccaaaa
     3301 gaccacgaag aaaaccatca agccaaacga cgtgtcgttt ttgaagagtt ctttttattt
     3361 caaatgcgtc ttcaaggatt gaaaaaagca gaaaaagcag aaacgaatgg tttggagatc
     3421 ctttatgatg tccaaaaatt gaaagaattt actcaaaagc taccttttga actgacaaat
     3481 gcacaaaaac gtgtaacgaa tgaaatctgt cgggatcttc gcagtccgca gcatatgcag
     3541 cgacttttgc agggagatgt aggtagcgga aaaacagtgg ttgccgcgat tgcgttatac
     3601 gctaccgtta cagcaggttt ccaaggtgcg ttgatggtgc ctacagaaat cttggcacaa
     3661 caacatatgg aaagcttgca acagctgttt gatcccaatg aagtaaccat cgcattgctt
     3721 acggggtcaa cgaaagcaaa agaacgtcgt gagctccttg aaaaactaga gcaaggggaa
     3781 attaacatcg tgatcggcac acatgcattg atccaagatg gagtcgaatt tcagaattta
     3841 ggtctagtta ttacggatga gcagcaccgt tttggcgtga accagcggaa agtacttcgt
     3901 gaaaaaggct ggcgaccaga tgtcttattt atgacagcga ctccgattcc tagaacatta
     3961 gctattacag catatggtga gatggatgta tctatcattg atgaacttcc agctggacgt
     4021 atcccgatcg aaacacgctg ggtaagaaca cctcaattgg acagtgtact ggattggacg
     4081 aaaaaagaac tggcaagagg acatcaaatg tatgtcatct gtccgctgat tgaagaatca
     4141 gaagcattag atgtaaaaaa tgcagtggaa atctatgaaa aacttcgtga actatttgca
     4201 ccaaaatatg aagttggctt gttacatggt aaaatgaaga atcaggaaaa agaagtaatc
     4261 atggaagcct tcaaagacaa ccagatgcag atattagttt cgactactgt aattgaagta
     4321 ggggtaaacg tgccgaacgc gaccgtcatg ctgatcatgg atgcggatcg atttggattg
     4381 gcacagctgc atcaacttcg tggacgtgtt ggacgcggaa gtgatgcttc ctactgtatc
     4441 ttagttgcta atcctaaaaa tgaactaggt gtggaacgga tgaaaatcat gacagagacc
     4501 accaatggtt ttgtactaag cgaaaaagat ctggaattac gtggtcctgg tgaagtattt
     4561 ggcttccgtc aatctggtct gcctcaattt gcgattgctg acttggtgac ggatggaaat
     4621 gttttggagg tagccagaga agaggctgca gccctttggc agataaagga ttggcagatg
     4681 cttcctgagt atcagccttt agcgcaaagc ctccaaatag aaaatcagga taatcgttat
     4741 ttcgattagc agactgtgct atactttata ctgatgacgg aaaaaggagt ggaaacaatg
     4801 aaaattgccg tagatgcaat gggcggagat cacgcacctc aagcaattgt agaaggcgtg
     4861 gctttagcgc agcaagattt tccagaagta gaattcttac tttacggaaa agaagcagaa
     4921 atcaagaaat acttaacaaa tgaaaaaaac atcacgatta tccatacaga cgaaaaaatc
     4981 aatagtgatg atgagccagt aaaagcaatt cgacgaaaaa agactgcatc aatggtcctt
     5041 gctgcacaag cagtgaaaaa cggtgaagca gatgctgtat tttcagcagg gaatacaggc
     5101 gcgctactag cagcagggtt gttcatcgta ggacgtatca aaaatatcga acgccctggc
     5161 ttgatgtcta ccttgccagt agtagggaaa gaaggtgccg gtttcgatat gctggatctt
     5221 ggcgctaacg cagaaaacaa accagaacat ttgttgcaat acggtatttt aggttctttt
     5281 tatgcacgta aagtccgagg tatcggacgt cctcgtgtcg cactcttaaa caacggaaca
     5341 gaagcaacaa aaggtagtga agtgacgaaa aaagcctatg aactccttca gaatgaaaca
     5401 agcttgaatt ttattggaaa cgtagaagct cgtgagctac tcaatggtgt ggctgatgta
     5461 gtggtcacag atggatttac aggcaacgct gttttgaaat ctattgaagg aacagcaatg
     5521 aatatgatga atctattaaa atctgctatt ctaaatgaag ggatcaaagg aaaaatgggc
     5581 gctatgcttt taaaagacgg cttacgttct ttgaaagcag aaatggatta ttccaaacat
     5641 ggcggtgccg ttttgtttgg cttgaaagca ccagtcatta aaactcatgg agcaacaggc
     5701 cccgatgctg ttcgctatac gatccgccaa atccacacaa tgcttgagac agatgtagtt
     5761 ggacaattag tcgaacaatt tgaaaaaagc gaagaatagt atttggatat ctgaagcaat
     5821 ccgttccatt gaaaaaaagg tggacattcc tgaaaaatgc cagtaaaatt agccatggtg
     5881 taggtaattg acaagtgtat gattcttgga ggtgaaaaag ttgactcgcg aagaagtatt
     5941 taacaaagta gcgaaaatta tttcaaatca ttttgagata gataccgata aagtgacgga
     6001 tgaattgaac atcaaagatg atttaaaagc tgattcaatt agtattatgg aattcgtttt
     6061 agagcttgaa gatgaattcg gtacggaaat ttcagatgaa gacgctgaac aaattgaaac
     6121 agtcggtggc gcagtagatt atatcagcag ccatcttaaa taatttcaaa taaaagcaaa
     6181 gaaggataaa aagctgcata cagcttttta tccttctttt tttaatcttt ttgacacgta
     6241 aaagtcattt ttctgataat tctggcgata aacagaaatt atgttgcaaa gtaaagcgat
     6301 tttctatata attattaata attcattaca caaagataag aataaccttt gttataaaac
     6361 gctttattct gtgtaatgtc cttttttatt aagaaaaact tccatttagg aagcagagag
     6421 gggtattcga ttgtccgata accaattatt agaagttcag aacctacata caggattccg
     6481 actcaaagat gactattacg atgcagtaga tgacgtttca tttactttag acaaaaacga
     6541 gattttagca atcgttgggg aatctgggtg cgggaaaagt accttggcta ctacgattat
     6601 gggattactt gatcctaata acacaaaaat tacaggtgag attttatata acgatctgaa
     6661 tttaatcgac ctgaacgaaa cgctctataa taaaatccgc ggaaatgata tcggaatgat
     6721 tttccaagat ccgttgtctg cattaaatcc tctcatgaga atcgaagacc agatcaaaga
     6781 aggactttcc tatcacacaa agatgaatgc agaacagcgt caagctcgtg cactagaatt
     6841 gctagaacaa gtagggattc ctaatcctgc gagagttgga cgccaatatc cccatgaact
     6901 atcaggcggt atgagacaac gtgtcatcat cgcaatcgca atcgcctgca aacctccaat
     6961 cgtcattgca gatgaaccga cgacagccct agatgtaacc atccaagcac agattcttga
     7021 tttactgaaa gaccttcagg aagaaacaaa aacagggatc atcttgatca ctcatgactt
     7081 aggagtcgta gcagaaatgg ctgatcgagt ggcagtgatg tatggcggac agttcgttga
     7141 agtagcaggt gtaaaagaac tgtttgatca tcctaagcat ccttatacac gctctttact
     7201 gaactctata ccacaagaag gaaatcatga tgcagaactc catgtgatcg aaggtgtcgt
     7261 tccttctctg aaaaacatgc ctcgtaaagg ttgtcggttt gcaccacgta ttccatggat
     7321 accagcaagc gatcatgaag aagagcctat ccttcatgaa gtcgcaccga accacttggt
     7381 acgttgctcc tgctataagc atttccactt tagagacgaa aaaggagagg tgtagatgac
     7441 agaattaatc acaatcaaag acctgaaagt tcattaccct attcgcagtg gattcttcaa
     7501 tcgagtaacg gatcatgtat atgctgtaga tggtgtggat tttattatcg aaaaaggaaa
     7561 gacatatggt ttagtgggag agtctggctc tggaaaatct actacgggaa aagccgttgt
     7621 gggattagaa aaggtaacag ccggacaaat catgtatgaa ggaaaagatg taacgaagcg
     7681 aagcaaccgc aaaaaaatgg gttataacaa ggatgtgcag atgatcttcc aagattcaat
     7741 gtccagtttg aatcctaaaa agcgagtgtt ggatatcatt gctgaaccca tccgaaattt
     7801 tgaacggtta agcgatcaag aagaaaagaa aaaggtaaaa ggactgctag atatcgttgg
     7861 gatgccggaa gatgcgctat ataaatatcc tcatgaattt tcaggcggac aacgtcaacg
     7921 tctaggagta gcccgtgctg ttgctaccaa tccaaaactg atcgtagccg atgaacctgt
     7981 atctgctctg gatctatctg ttcaagcgca agtattgaat ttcatgaaac gaatccagca
     8041 agaatacggc ctcagctatt tattcatttc acatgattta ggtgtagtaa aacacatgtg
     8101 cgacaatatc gcaattatgt acaaaggtcg atttgtagaa atcggtacaa gagaagacat
     8161 ttataatgac ccgcgacata tctatacgaa acgtctgctt tcagctattc cgcaaatcga
     8221 tgtagaaaat agggaaagcc acaaagaaaa tcgacgaaga gtagaacaag agtatatcca
     8281 aaaccaaaaa gaatactatg atgcgactgg tcgagtctac gatttgcgta cgatcacaac
     8341 tacacacaaa gtggcgttga aagatggagg tgcaagctaa tgtggaaaac gattctgcga
     8401 cgtgttttat tgatgatccc gcaagttatt attttaagtg ttctgatctt cttattagcc
     8461 caagcgatgc cgggggatcc atttaccggt ttgatcaatc caaatcagga tccggcagtg
     8521 atcgaacaga tgcgacaagc agctggcttg aatgacccat ggtatgtcca gtacttccgt
     8581 tggatcggaa atgctttgca aggcgatttt ggtcaaagtt tcttatacaa acgctctgtt
     8641 gctgacttga tcggcgaacg gatcatcaac actttatatc tatcgatctt gacagttgtc
     8701 cttacttatt tgattgctgt gcctctgggg atgcttgctg gccggtatca aaattcaatc
     8761 ttggataaga ttgtcgtaat ctacaacttc tttagttttg ctgttccttt atttatcttc
     8821 ggcttgatca tgctatttgt ttttggttat cgtttaggct ggttcccaac aagtggatca
     8881 caaacactag gtttgcaagg tggatttatc actcaatgga tagaccgttt gaaatatatt
     8941 ctgttaccat caattaccca agcatttttg gcgactgccg tcacaatcca atatctgcga
     9001 agtgaagtaa tcgattcgaa atcgctcgat tttgtcagaa cagcccgttc caaaggggta
     9061 ccgacgaata aagtattcag tcgacatatt ttccgaaatg cagcgttgcc gatggcttct
     9121 caaatggggt atgaaatcac ttcgttgatt gctggttctg tagttatcga aaagattttt
     9181 ggttatccgg gagtcggaaa actatttatt gattccatcg gccaacggga ctataccgtg
     9241 atcacatcct tagtattgat tttaggaatc gcgacgctag tggggacatt actttcagat
     9301 atcatcatga gtatcgttga cccgcgtatt cggattcaat aaaaccaatc agaaaggaga
     9361 atggatcgat gagtgaaaaa aacaatacag cagttcaaga aagtattcct cctatgggga
     9421 tacgaatgat tgctcgagaa tttaaaaaag ataaaattgc tattttttca ttaggtttgc
     9481 tagtggtttt attattagtg atctttatcg gtgcgatgct gaccgatcaa gacaaagtga
     9541 tgtatgttag tatcttcgac aaatacgctg caccaggaac agtttcgaca caaggacaaa
     9601 agttcattct gggagcagat gaaggcggac gtgatgtatt aggacaattg atcataggtg
     9661 ctagaaactc tgttacgatc ggatttgcga tcacgatcct tacttcgatc atcggggttg
     9721 gattagggat catctctggc tactacggag ggatcattga caacatcttg atgcggatcg
     9781 ttgattttat catgattcta ccgatcatgc tgatcattat cgtcttcgta tcgattattt
     9841 ccagatacaa tgtctggtcc tttatattca tcatgagtgc attttattgg gtagctaaag
     9901 cccgattatt ccgaagcaag acattatctg aagcaagaag agattatgtc agtgcctcaa
     9961 aaacaatggg aaccaatgat tttaaaatca tgttccgcga aatcatgccg aatctaagtt
    10021 cattaatcat tactaatttg acgatgaact ttgcggcaaa catcggtatc gagacaactt
    10081 tgactttctt aggtttcggc ttgccggcaa atgtacctag tttaggtaca ttgatcggtt
    10141 atgcaagtaa cggagaagtc ttagtgaatc ggcaatggat ctggttaccc gcatcaatcc
    10201 ttattttagt tttgatgttg agtatcaatt atgttggaca agcattcaag cgttctgcag
    10261 atgcgcgcca acggttaggc tagtatagaa gcgaaggggg aaataggaat gaagaaaacg
    10321 atttttggat ttgcagcgct gatgtctgct gtcgttcttg cagcatgcgg gggcggaggt
    10381 acagatacct ctggaaacaa ctctggaggc aacggcaata acaaagagga attaactttt
    10441 ccaattgcaa caaaaaataa tgatgatgca atcgaagacg gcgaattaga agctgcggtc
    10501 gcaacggaca gtcagtttaa aggattgttc cagtgggagt tttaccaaga ttcatatgat
    10561 gcagctttta tggctccttc tcatgaaccg ctatttgcaa acgatgacga tttcagaatc
    10621 acagacgacg gagctgcaac gcttgatcta gatgaagata cgaaaaaagc gacaatcaaa
    10681 gtaaaagaca acgtcaaatg gtcagatggt gaagatgtaa cggcggacga tgtgattttc
    10741 ccttacgaaa tcattgggaa taaagattac actggtatcc gttatgacga cactttccgt
    10801 aacatcgtag gtatggaaga atatcatgat ggaagtgccg acacaatctc cggaatcaaa
    10861 aaaatagacg acaaaacagt tgaaatcgaa tataaagaag taaacccaag catgcttcaa
    10921 tcgggtggtg gtatctggtc atatgcagca ccaaaacata cgttagaagg tgtagcaatc
    10981 aaagatatgg aatcaagcga tcaagtacgt aaaaatccag tgacttttgg cccttattac
    11041 atgagtaata tcgttgcagg agaatcagta gaatacttgc caaacgagca ctactggaat
    11101 ggtacgccta aattgaaaaa gatcacgatg aaatctgtac cgatggcaag tgcaactgaa
    11161 gcattgaact ctaaattata tgatatgatt ttccaaatgc caacagatac ttacgatacc
    11221 tataaagaaa ttgctggcta tacaaactta ggccgtgaac aaacttctta tacttatcta
    11281 ggattcaagt taggtaaatg gaatgcagat acaaagagtg tggaatacaa tccagattca
    11341 aaaatggctg ataaatcatt acgtcaagca atgggctatg cattagataa taatgcagta
    11401 ggtgaacgtt tctatgcagg tttgagaagc aatgcgactt cattgattcc tccagtattc
    11461 cagtcatacc atgatgatga gatgaaagga ttcacacaag atctagacaa agcgaaaaaa
    11521 ctattagatg atgctggcta caaagatgtg gatgacgatg gtttaagaga agacaaagat
    11581 ggaaataaac taacaatcaa ctttgcttcg atgtccggtg gggaaacagc gcaaccattg
    11641 gcagattact atatccaaca atggaaagaa attggtttgg atgtccaata cacaacaggt
    11701 cgtctgatcg aattcaattc tttctatgat aaattagaaa acgatgatcc tgaaattgat
    11761 gtttaccaag ctgcttggaa tacaggaact gatccaaatc caagtggact atggggacca
    11821 aatgctgcgt tcaactacac tcgttatgaa tcagaagaaa atacaaaatt gatcaacgat
    11881 atcagttcaa gcaaagcatt tgatgaagag taccaaaaag aagcatatca aaaatggcaa
    11941 caatatgcat ttgaagaagc atttgcgatt ccaacgttgt tccgtaatga agtattgcca
    12001 gtcaacgacc gtgtcaaaga ctgggattgg tcttatgatg taccaaaccc atgggcaaat
    12061 gtttctgtta cagcagattc acgttcataa tcactaaaaa tgaccgaaaa agggcgatgt
    12121 cctttttcgg ttttttgata tttttctgtt tatttctcta atattcaggt caaggcgctg
    12181 atttcatgac ttctccaata aacggtgttc aaagtccagt ttctcggtat taagtcaaat
    12241 ttatgcaaaa atatggaaag ccattttcac aaaatttttt cttcatactc gaaactaaac
    12301 gaatttttca caacttctcg tcaatcacta ggattattaa agctttactt accttttgac
    12361 cgaaccattt caaatttgac aaaaaaccag tataataagg aagtatcgaa aaaatatcca
    12421 taaaaggaat gtggaaaatg gacaaccagc tgacaaaaga actaaaagaa aactataaca
    12481 tcgtttttca cgatctaaat ttgcttgaac aagcttttac ccattcatcc tatgtgaatg
    12541 agcatcgcaa tctgcaatta tcggataatg agcgacttga atttttagga gatgccgttt
    12601 tagaactgat ggtttctcag tatttattcc gtttatatcc tcatttgcca gaaggaaaat
    12661 tgacaaaaac acgagctgcg atcgttcgcg aagacagctt gtcgaaattt gccaaagaat
    12721 gtcactttga tcaatatgtt ttgttgggca agggagaaga gaattcagga ggacgtacgc
    12781 gaccagcatt gctttgcgac ctattcgaag cttttttagg cgcgttatat cttgaccagg
    12841 gattcgacac gacccatgca ttcatcgaaa aagtgatttt tcctaaagtc aaagcaggtg
    12901 ctttttcaca tgagatggat cataaaacaa aactacaaga agtcttgcaa aaatcaggtg
    12961 atgtatcaat cgaataccga ttgatcaatg aagaaggtcc agctcatgaa cgagtatttt
    13021 ggatcgaagt ttatgtagat gatcaattga ttggcactgg acaagggaaa tcgaaaaaat
    13081 tagcagaaca agctgcggcg gaaaatgcat tggcagcact gtaaaagtaa gtgagggaaa
    13141 gctttgtatt tgaaacgaat tgaaatagcc ggttttaaat catttgcaga caagacagtc
    13201 attgattttg aaaatagcgt cacagcagtg gttggaccaa atggcagcgg aaaaagcaat
    13261 attacagagg ctatccgctg ggtattagga gaacaatctg ctaaaagtct gcgaggcgga
    13321 aaaatgccgg atatcatctt tgccggttcc gatacccgta agcagctgaa tattgcagaa
    13381 gtcacagtga ttttagacaa tagtgatcat tatctgccat tggagtacaa tgagatcagt
    13441 gtaacccgcc gttatcgacg gactggggaa agcgagtttt tcatcaataa acaaagctgc
    13501 agattaaaag atatccaaga attgttctta gattctggat taggaaaaga atcgttctca
    13561 atcatttctc aaggaaaagt agaagcgatt ttcagtagta aaccggaaga ccgtcgtggg
    13621 atctttgaag aagcagctgg tgtcttgaaa tacaagcagc ggaaaaagaa agcagaacag
    13681 aagctttttg aaacagaaga caacctcagc cgcgtccaag acatcatcca cgaattggaa
    13741 gaacagttaa ctcctttggc cgcccagagt gaggcagcaa aggagttttt acggctaaaa
    13801 gaaacactga ctcaaaccga tgtctctttg atggttgctg aaatcaagac agcaaaaaaa
    13861 gattgggaca acaaacaagc acagcttgcg aaattcaatc tagaattagg caaactatct
    13921 gagtcgatcc aagaacaaga atccattttg gcgaagcagc gtaaagaaaa tgcgcaagcc
    13981 gatcgtctga tcgaaaaaaa tcagcaagta ttattagatc tttcggaaaa actgaagcag
    14041 acagaaggac aaaaagatgt tttgcaggag cggacaaagc atacacaaaa aagctcgcaa
    14101 gaatatcaaa cttcattagc agaagcacaa aaaaaggtta aacattttga aaagcttcaa
    14161 gaaagcttga tgaaagcagc agcagaaaaa gaaacagaga tccaaaaagc tgaagcaaat
    14221 ctcataaaaa cacagcaaga attagaaaaa taccaaaaat caacgaaaga attattggca
    14281 gaattaagag atcaatatgt tgatttgatg caagaacaag cagctgtagg aaacgaactg
    14341 aagtatctag aacgtcaata tatacaagaa acagcaaaaa gcaagcagac gttagccaag
    14401 caatcggaag tagaagcatc agtagaccga ttgatcttac aaaaagaaga attgacacaa
    14461 aagcaggcgc agctaaaatc atctttaact gaaacaaaag agaagttaga aatgatccaa
    14521 caaaacggga aaaagttcca agaagcatta gcaaaagaac agcctaaaat gtatcaatta
    14581 atgaatcaag tccagcagct acgtgctcgt aagaaaagcc ttcaagaaat ccaagaaaac
    14641 tattttggtt tttaccaagg ggttcgattg gtcttgcagc ataaacagca gctttcgggt
    14701 attgtcggag cagtggctga actgatcgat gttcctgcag atttcacgtt agctatcgaa
    14761 gcagctttag gtggggcagc ccagcatgtc atcgttgaaa atgaaaaaga tgctcggcaa
    14821 gccatcacgt atttgaaaca gcaaagagga ggaagagcaa cattccttcc actgacgaca
    14881 atcaaaccaa gacaattacc ggctcatata ttgacacaag cagcagctgt agaagggttt
    14941 atagggattg ccagtgaaca agtcagttat cccgatcaaa tccaaactgt ggttcaaaac
    15001 ctgctaggaa cgatcctttt agccaaagac ttaactagtg ccaatgcaat cgcgcaaacg
    15061 atccgctatc aatatcgagt ggtttcctta gaaggtgatg tgatgaatgc cggaggatcc
    15121 atgacaggtg gagcgaataa acgaggaaac caaggcagtt tgtttgtaca aaatcaagaa
    15181 ttgaaacagt tgactagtga atttgaagaa gcagataaac aactccaagc acaagaaaaa
    15241 aaagttcagg agctgcaaca agaaacagct cgtttagccg aagaacaaga agttttgcgt
    15301 acacgaggcg aacaattacg ttttgaagaa caagaagcga caaatcagct acaaaacatc
    15361 ataaatgaac ttgaacgttt tgaaaaagaa aagcaaatct caacttttga gacacgtgaa
    15421 ctgcagcagt ttatcgaaga ttacgaaaag caaacgaacg aattgaaaga caaacaaaca
    15481 gatcttgaat cgcaacgaca aaaaatcgac gaagaaatca aatcgttaag tcaagaaagc
    15541 gaccagatgg aagccagaag agcacaagta caaagtcaaa aagcacaaga acaagcagat
    15601 cttgctgtct tgaaagagca gtttaatcat ctgcagatcc agctccgcgg tgcccgagtc
    15661 caaaaagcag aggcaaccga acgtcaagaa gcgatagaaa agcagttggc gacattgaca
    15721 gcagactttt ctgatcatga agtcacagaa gaaagtttgg aaaaacaaat taacgaatta
    15781 tctgctcagc gagaaacatt aaaagccgag ttggcaaaag ccaaagagca gcgagataga
    15841 aggcaaaagg agatcgataa gcttgaagca gtcttggcag agcgtaatcg tgagcaaaaa
    15901 gcacgactgt cggaacaatc caaattagaa gtccaaaaag accgagctga aatgatttta
    15961 gataatcatt tgacctatct gcagtcagaa tatcagctga catttgagaa agcttcccaa
    16021 gactatcaag aaacaaccga tatcgaagac agtagaacaa aggtttcatc cttaaaagaa
    16081 cagattgaaa aactgggacc agtaaactta aattcaatcg aacaatacga acaagtcagt
    16141 gaaagacata cattcttagc aacacagcga gatgatctgt tagcagcgaa aaaccaattg
    16201 tttgaaacga tggatgagat ggatgatgaa gtgcggacaa gattcaaaga agtatttgaa
    16261 gctatccgtc aagaattcaa aattgtcttt ccaaatatgt ttggcggcgg taaagctgaa
    16321 ttagtactga cggaaccaac tgatttgctg aaaacaggta ttgagattga agtacaacct
    16381 cctggcaaaa aactgcaaag tctaagtttg ctttctggag gagaacgagc acttacagcc
    16441 atcgcgttgc tcttttccat tatccgtgtc tgtcctgttc cgttttgtat cttagatgag
    16501 gtagaagcag cgttagatga agccaacgtg aaacgttttg gtcgttactt gagcgatttc
    16561 caagatgaca cacaatttat cgtagtcaca caccgcaaag gaacgatggt cgcagcagat
    16621 gtactgtacg gagtgacgat gcaggaatcc ggtgtatcaa aaatcgtttc tgtacggatg
    16681 gaagatatca atgaagaggc gaaaatcaac gaaacgaaag tgtaggaacg aaaatgatca
    16741 aattagtagc aatcgatttg gacggtacat tattaaatga acaaaagctg atttcagatg
    16801 agaataaaca agcattagca caagcaaaac agcaaggggt caagatcgtt ctatgtacag
    16861 gacgcccctt agctgcgatg gcgcattatc tgcaagaatt aggactggta gatgaaggtg
    16921 actacagcat cactttcaac ggcggtttgg tacaaaaaaa tgatactggt gaaatcatgg
    16981 aaaagaaagt gatggaagta tcagatatcc aacgcttata caaactggct cagcaattgg
    17041 atctgccact agatgttttg tctgacaatg tggttttaca gctgcctagt gccccaagga
    17101 agcaatcctt gtacaatgtg ttgaataagc tgctgcaatt ccaaccagcg gatataagcg
    17161 atattacaga tgaatttgtg cttaataagg cagtaatcgc ttatgaccaa gaagaattag
    17221 atcctaaaat caaagaaata ccagcagaat tccatgaaat gtatgagatc atcaaaacaa
    17281 gaagtatgct tttggaattt atgccaaaag gtgttacaaa agcttatggt atttctttat
    17341 tggcaaaaga tcttggtttg aaacaagaag aaatcatggc gatcggtgat gaggaaaatg
    17401 atttaccgat gatccaatat gctggactag gcgtagcgat ggagaatgct gtgcctttcg
    17461 tcaaagaagc agcagatttc gtgacagcca gcaatgaaga aaatggcgta gccaaagtga
    17521 tccaaaaatt tgtattagag tagggggagt caaatgggat tttttgataa aatcaagcgt
    17581 gcttttactg gcgaagagaa aacagaagaa gttgaagtac aggagaagta cgacaagggt
    17641 ttagaaaaga cgcgtaaaac atttggtgaa cggatgaatg agttgtttgc caattttcga
    17701 acagtcgatg aagacttttt tgaagaatta gaagaaacac ttatcggtgc agatgtaggt
    17761 tttgaaacag cgatacgaat caccgaagca ttacgtcaag aagtgaaact cagaaatgcg
    17821 aaaaaatcgg cagaagtcca aaatgcgatc atcgagaaac ttgtggatct ctatgaagcg
    17881 gaaggaatca atgaagtaaa tgaactaaat atccaagaag acggactaac agttattttg
    17941 tttgtcggtg ttaatggtgt agggaaaaca acaagtattg gtaaacttgc ccatcagttc
    18001 aaaaacgaag gtaaaaaagt attgatggca gcagcagata ccttccgcgc tggagcaatc
    18061 gaccagttag ttgtctgggg cgaacgcgct ggtgttgaag ttgttcgtgg caatgcagga
    18121 ggcgatccag cagctgtcgt attcgatgct ttggaaagag caaagacaga gcaggcagat
    18181 gttttactag ttgatactgc aggccgactg caaaataaag tgaacttgat gaacgaatta
    18241 gaaaaaataa aacgagtaat ccagcgggaa ttaccagaag caccccaaga aacacttctt
    18301 gtattagatg caaccactgg tcaaaacgcg atggttcaag caaaacaatt caaagaaaca
    18361 acagatgtga ccggtcttgt tttgacaaaa ttagatggta cagcaaaggg cggtatcgta
    18421 cttgctatcc gtaatgaatt gcatttacca gtgaaattgg tcggtcttgg tgaaggaatc
    18481 gatgacttgg agccgtttga tccaaatgat tttgtcgttg gattgttcaa aggattacta
    18541 aaagaagaat aacccatgtc taaaaagcag gagctgtgac aaaagttgca gctccttgtt
    18601 tgaatgattg tttttaacat agctgtgttt ttgatgcctt catttttata cttatttgta
    18661 agcggttctc aaacaatttc gttctttttc ttagactttt tgattataat tagattcata
    18721 tgaattggag gtcacttaat gatgaatttt aagcaattat tattgcatgt caatgcgcgc
    18781 ccttttatcg accaagctcg atttggtata gaacgggaag gacagcgggt tgatcttgca
    18841 ggaaatctag caaaaaccga tcatccagca atctttggcg atcgatccta tcacccctat
    18901 atccaaacag attttagcga aacacaaaca gagatgatca cccctgttac cgattctatt
    18961 cccgaattat ttcagtatct cgctgctgtt tatgatgtga ctgctcgttc tataccgaaa
    19021 gaagagatga tctggccatt aagtatgcca cctgccttac cggaaaaaga cgaagagatc
    19081 attattgcaa aattaaaaaa tttcgaagat gtcttgtatc gacgttattt agcaaaaaaa
    19141 tacgggaagc gaaaacagat ggtaagcggt attcatttca attttgaatt tggcgatgag
    19201 ttgctaagaa cattgttcag ccatcaggaa gaatttcaag atttttccga attcaaaaca
    19261 gaactttatt tgaaaacagc gagaaacttt atgcgctatc gctggatgat cacttattta
    19321 ttcggtgctt caccaatgag tgagaagaac tactttttag atgaatcaca tccgcaagaa
    19381 cctgttcgca gtattcgcaa cagtgcgctg ggctatacga atcatccaaa tgtgaaagtt
    19441 tcctatgctt ctatgaaaca gtatttagca gatatcgagc gaatgatcga agaagggaaa
    19501 ctttcggagg agaaagaatt ttatacaccg cttcgtttcc gaggcggaaa gaaagtcgca
    19561 gatttagcaa caacaggtgt tcgttatatt gaattgcgga atatcgattt gaatccttat
    19621 gcaagattgg gtatcaatcc agagcaagtt cggttcttac aattattcct gatgtacatg
    19681 ttatggacag aagaaaaaga agactgtgac caatgggtag cagaaggtac gactcgaaat
    19741 aacaaagtag cactagaaca accatcagat caaacagaat ttcatcaaga aggtagagaa
    19801 attcttgaag gaatgaagca aatgctggtt gaattggatt ggttggattc tctttattta
    19861 gtagaggaag cattgactca aatggatcat cctgaacaaa cgttagcagc gaaactctat
    19921 caagaagcac agctatcgag tcagcaagaa gttgctgtgg cattgggaca tcaatattat
    19981 aaagaaagcc atgaacgtcc ctatcagttg gccggttttc gcgaaatgga actttctact
    20041 cagatattta tgttcgatgc catccaaaaa ggtgtccaag tcaaagtatt agatgagtcg
    20101 gatcaatttt tgcgtctgca attccaagac catgtagaat atgtgaaaaa tgcaaacatg
    20161 acaagtaagg acagctatat cgtcccactt atcatggaaa acaaaacagt aacgaaaaaa
    20221 gtcttaaaag aagctgggtt ccgggtacca ggaggcgcag aattttcatc catggaagaa
    20281 gcggtaaaag cttatccgag atttgccgag caggcatttg tgatcaaacc taaatcaacc
    20341 aattacgggt taggtatcac gattttcaag gaaggagcta gtctggaaga ttatcaagca
    20401 ggtttagcca ttgcttttcg tgaagacagt tcggttttag tagaagaatt tatgccggga
    20461 acggaatatc gtttctttgt gatcgacgga gaagtccaag ccatcatgtt gcgagtccct
    20521 gctaatgtta ttggtgacag tatccgaaca gtgaaagaac ttgttgaaga aaaaaatagt
    20581 gaccctttgc gtggaacgaa tcatcgtgca cctttagaat tgatccaatt aggtgaatta
    20641 gaacaattga tgttgaaaga acaagggttg acgatcgaat cagttcccca agccaatcaa
    20701 attgtttatc taagggagaa ctcaaatatc agtacaggtg gtgattcgat cgatatgact
    20761 gatgaatttt ctgaagctta caaaaaaatc gccgtttctg cggtagaagc actaggagct
    20821 aagattagtg gtatcgattt gattatacca gataaagaaa tcgatcctac aactgataaa
    20881 aaagcatatg ggatcatcga agcaaatttc aatccagcca tgcatatgca tgtttatcct
    20941 tttgcaggaa aaggcagaag attgacgatg aatgtattga aattgttata tcctgaagta
    21001 ttttaaaaga aaaagctttt gacagattgt cctatttgat gtcaatctga tcaaaagctt
    21061 tttttgcatg taaaaattta tgtgtttttt cgttttaaaa taaacgatcc cagaagcttt
    21121 ttttcttttt tggtttttct ttttcagctg gcgaagagtt ttcttctggg tatttttttt
    21181 cgatatcaat cacaggttca tttactgctt cttttgctgt taagagcaat ccgaattcct
    21241 caggatttgc agtgacgtaa tcgttgacta cagtgaaacg gctattgttt ttcgttgcta
    21301 gctggatata ttggttttgg acagaaaggg gtagagcccc attcaagagt atggaagcat
    21361 ctggatgttt tttgagttct tttaaaaagt tttctttgtt ttttggttgg atcatttcag
    21421 caacagtcat actaagatag cagcgttccc tgaatgtccc taaatattta tgctgttctt
    21481 cagggttcac taaaggtgta ccataaagtc ccttatccaa atggcttttt acatcatctt
    21541 gtgccataaa aaataccctc cttcttctct ttgtctttct tacgattata gcatattccc
    21601 aataatacct aaaacatatg aaaaagcggt tgcttttgtt caacgattca cttaaaataa
    21661 gaatgaaaat cattctcaat tagaaaggtg gattggatgc gctacggacg actagtagca
    21721 ttattagtta ttttaagtag tatttcattg ttcatcggag tatcgaatgt acaattgtca
    21781 gaactgctcc agttagatgg gcaaagctta caaatcttgc tagtgactcg tttgccacga
    21841 acgatttgtt tgatccttgt gggagcgacc agtagtattt gtgggttgat catgcaacat
    21901 ttgacccaaa ataaatttgt ttcaccaacg actgcgggca cgatggatag tgcgcgttta
    21961 ggtattttag tggctatgat tttcctacct ggtgcatcct tgattgtccg atccttgaca
    22021 gcattttgct ttgcttttgc aggaacattg ctttttttat cccttacgcg attgttcctc
    22081 cagaaaaatc aattgatgct tccgttgatt ggagtcatgt tagggaatat cattggttca
    22141 gttgctactt tttttgctta tcaattccag ttggtacaaa atatgacttc atggcttcaa
    22201 gggaattttg cgactgtgat acgaggaaat tatgagttat tgtatgctgt tgttccattg
    22261 ttgctcttgg tttggctatt tgcttaccga tttacgatca ttggtctggg cgaatcgttt
    22321 gcagtaaatc tgggaataga ttaccagaag atgcagtttt taggcattgg cttagtatca
    22381 ttggctagtg cagtcatgtt gatcatggta ggaagcattc cttttatcgg agtgatcatt
    22441 ccgaatcttg tctctagaat atatggagat caagtgcaca aaacaattgg cgtaactgct
    22501 ttagcaggta gtttgttctt agtattttgc gatcttgtcg ctcgcgtgtt gatttttcct
    22561 tatgaaatac cagtcagtgt gatcgttgga atcatcggtg gggctatctt cctttatctt
    22621 ctgataaggg gacgacgata tgcttaaaaa aaagccatct atttttattg gtatgcttgt
    22681 tcttgtttta tttgttacag gaatgtactt gacgatccat acatatggaa actggcattt
    22741 tgcatgtgca ttgaggagta agaaaatttt tgcatttatc cttgtctcgc tagctgtcag
    22801 cagtgccaca atcagctttc agacaattac gcataaccag tttttgactc cttcagtatt
    22861 gggacttgag tcgttatatg tccttgtcca aacggtcctt ttcttcttta tcggaggagt
    22921 gacgatgctt cagcagacag gtacagtttt tttcttattg aacgttgggc tgatggtcgg
    22981 gctgagtcta ttgttatttt tctttctttt gaaaaaaatg agagcgaatc tttttttatt
    23041 actgatgtca gggatgattt taggtacgct ttttggtagt gtcagtacct ttttacaagt
    23101 catcatggat ccgaatgaat atgatttgct tcaaggcaga ttatttgcaa gctttggcaa
    23161 tatccagagt cagtatcttt tgcctgcttc tttgatcatt atcggctgct ggtacctgtt
    23221 atttcgatat cgacatgtgc tagacgtttt ccatctcgga aatgaacaag cagtaaacct
    23281 cgggatagac acagatcgtt ttgaattttt gattttatgt tgtgtcagtc ttttgacagg
    23341 gacatcaacg gctcttgtgg gtccagttac ttttttaggg tttattgtcg caaatatcag
    23401 ttatcgtgtc ttttctactt atcgtcatgg tcagctattt atcggaagct ttctggtagc
    23461 tatgctgttt ctgacaggag gacagctcgc agtagagcag attttcggct ggaatacaac
    23521 agtgagtgtc gtcgttgaat ttgtcggagg aatttatttt gtcacaaaat tgattcgcga
    23581 aaggaagagt atcctatgat tgatttacaa aaggtcaata aactgtacca tggaaaatca
    23641 gtggttaaag atgtacagtt aacgattcct gaaaagaagt tgactgcttt tatcggtcca
    23701 aatggtgctg gaaagtcaac ggtgttgtcg atgatcagtc gtttgatacc aaaagataca
    23761 ggtgaaatct atttagacca taacgaagta aaggcttgga aatccaatga attagccaaa
    23821 aaattatcga tcctacgaca atcgaatgaa ataaatgtcc aaatcaccgt gaaagaatta
    23881 gtagaatttg gacgatttcc ttatacgaaa ggaaaattga cgacaaaaga cgaggaaatc
    23941 gttcaggaat cactggaaca ccttgggtta gaagaaatag cggatcaatc gattgacact
    24001 ctttcaggcg gtcaactcca acgtgcgtat attgcaatgg tgctagcgca agacacggat
    24061 tatattttac tggatgaacc tttgaacaat ctagatatga attttgcggt tcaaatcatg
    24121 cagattttaa aaaatttagt acaagaaatc gggaaaacaa ttgttattgt tcttcatgat
    24181 atcaactttg ctgcaagtta tgcagacgaa attgttgcaa tgaaagatgg acagttattt
    24241 acgcaaggaa cgacccaaga aatgataaaa aaagatgtat tggatgaatt atacgaaatg
    24301 gacatacgga tttgtgagat tgaaggccgc agattctgtc tttatttcta aaactaacat
    24361 taggagagaa gagatgaaaa aattagtagt aggtatcttg attctagcat catttggttt
    24421 agcagcatgt ggaaatagca acaacaccag tcaggcagac acaaaaaaaa gcagcacaca
    24481 aactgaaact acattgacga taacagatag taatggagac caaatcgagg tgccaaataa
    24541 tccagaaaaa gtcgtcgtat tcgacaatgg ttctttagat acgatggatg ctcttggtgt
    24601 tggagataag gtagttggag cagctacaag cagccttcct gagtatcttt catcctataa
    24661 aaaagtagaa tcagcaggtg gaataaaaga accagactta gaaaaaatta atcagcttca
    24721 gccagatcta atcatcattt ctggccgaca aagagatttt caaaaagatc taagtcaaat
    24781 tgctccgacc attttccttt ctttagatgc gaaaaatcca tgggaatctt tccagcaaaa
    24841 tgtcactgct ttaggggaga tctttggtaa gcaagaagaa gctaaaactc aattagagga
    24901 attatctagt gcaatcgatc agacgaaaaa gaaagcagaa gctactgaca aaaaagcact
    24961 agtcacactt gtgaatgaag ggcaattatc agcctacgga tctggttcta gattcggttt
    25021 catccatgat ttatttggct ttgaacaagc agatgatcaa atcgaagcat ccactcacgg
    25081 tcaaagtgtt tcttatgaat atgtgctgga aaaaaatccg gatatcttat ttgtagtaga
    25141 cagaacaaaa gctattggtg gagacgacag caaagatgat atttctgcca atgaactggt
    25201 agcacaaacg aatgctggta aaaatcagca gatcatctcc cttgaaccag atgtctggta
    25261 tttaagcggg ggcggtttag aatcaatgaa actgatgatc gaagatgtga atcaagcatt
    25321 taaatagcat aaataacaga ggattaaact ctcatactat gtaacaataa tgtttcttac
    25381 attcttaaat agcaagagcc tatcctcaaa gaagttatca aaaaccatcc gtaaaatcgt
    25441 attgatgatt ttacggatgg tttttattta tttgagaaat cttttttcaa cgtgaattca
    25501 ttatctacat catacgggtt gattctagaa tggggagtgg caaaaaatag tgtgatccat
    25561 tttttcagca tcaagatcgc ctcctttgat ttgaatcaaa ggtacaaagc gaaacttaga
    25621 taaaacttaa atttagatat ttttattttg taccgatctc ttctttaaac gatgttccat
    25681 ctgctgcttc tcggcaataa gtccactaga ctagaaaata tgagaagcta ttttctgtcc
    25741 agcgttctta ttactcaaaa caaatcgcag ttgtcacaat ctcttctaaa cgatgttcca
    25801 tctgctgctt ctcggcaata agcccactag actagaaaat atgagaagct attttctgtc
    25861 cagcgttctt attactcaaa gcaaatcgca gttgtcacaa tctcttctaa acaatgttca
    25921 atcagctgac cttcggtatt agctcaaagc actgatttca caacctctat ttaggcatgt
    25981 gtctcagcaa gcggttgata gttgatgatc tgcatttttc gataaaaatc ggcgggaagc
    26041 ttactccacc gttttagtaa ttgatagaaa taactctctt ctgctttgat tttatactcg
    26101 cttaatatca atccaaaact attcgttttt tttgaagcta attttttata aatatccaat
    26161 gctttggttt tatcttcatt gacaaagagt gtttttactt caatataaga accctcgata
    26221 ttttgtgttt cttcgataaa atagatgttt tttatatatt ccttcatagt gattcctcca
    26281 aagaagtctt ttatttgata agtttactct accgaagagt tgttaataat ccgtgaacaa
    26341 aaagtaattc tttttccaat agttgttaaa ggttttttat tttttatagt attttttgtt
    26401 atttaagaaa ggaataaggt taaacaaata acaggttgct ttttgggtct ttttccgttc
    26461 aagaaactga acgaagaaaa gggaaagttg tctcttttgt gataagagaa atcataataa
    26521 acgaatgact tactttccaa taaattgaga acagtcagaa ccagacaaat tagttgcatc
    26581 tgatgaataa agtgattatt ctatgacatg aggtgataca gatgaaatta gaagtgacaa
    26641 aagaagcaca agaagtattg aagaataaat tagaagcaga cgatcaactt ttattagata
    26701 tcgaaaacgg tgacggtcca tttgcagaaa gccaagtcag ttgccaattg gatacggcat
    26761 ttcgattgat cattgtcaaa aaagatacac aaacagatct aagtctttat tctgtagtgg
    26821 ctgatacacc agttggacca atcaaaatca aagacagtgc aatactttac atggatgatc
    26881 catccacact tgctttagaa ccaacttata atagtttaca attaaaagga ccaagcggct
    26941 tgagaaaagg caacttgcaa gttgttcgaa aagactagag ggataaaatg ggaaaattgg
    27001 cgatcatcag cgacctacat gtggacatca ataaattcgg cgaatcagag ctgatgcagc
    27061 tttggcaagt tttgcaaaag cacaagatca ctcggcttca tctagccgga gatacggcta
    27121 ataaagtaga ccgttgccta gctgttgtcg aatttttcgt caataaagga ttatctacga
    27181 catttcattt cggcaatcac gagttggcag atgtgcccaa tgaacagatg atggaccatt
    27241 ttccagaccc acatttttta aatgaacggt atattgcttt aaatgagcag accgttcttt
    27301 tagggatgaa tggctggtac gactatcagt tttccgaatt gaaagattac gaggcaatcg
    27361 tacgaatgaa gcgtttgtat tggtatgatc ggttcatcca gcgtgggaaa acagatctcg
    27421 aggtcaatgc agaaatgctt gcagctgcaa aaaatttgct agaccagctg gaagcaaaaa
    27481 aacttgaggt gattttatcc actcatttcg ttcctaaacg ggcatttatc atgtatcaat
    27541 ctgctcctta tgagcgttgg aacaaattaa atgcattttt aggatcagaa tcattcggag
    27601 aattacttga ccgttattca aatatcaaac aagtagtttt tggccatacg catcgtcgct
    27661 ttgaagataa atccatcggt cacacgattt acagctgcag accttttggt tattattatg
    27721 aatggcagct gacccgagat tttgtcttga aagaacagtt gctagacagc tatgatccta
    27781 tgaaattacg tgtcctcttg cgtgcccatc acccagcttt tcaggcctat caaacacaac
    27841 atttgcaaga ggaatttgaa caagcgatga caatcgttcc gtattgagac agcattagta
    27901 atgtgtaaaa gaaaatacct tgtaaaacat aaggataagt aagagcagta gatccattta
    27961 tcgtggatat gctgcttttt ttgcggaaaa taatcagcga atgtttattt gatcggatga
    28021 tttgtaactc gcagagtact agatgcaagc gtgtattctt tttttgaacg ataatcacaa
    28081 aaaaaaatat aatatacatt ttttatttaa ttataattaa tattgattga agtctaggca
    28141 gtcaagtcac attttgatag ataggagggg gacttacgaa ttattttaaa ggctatgaca
    28201 gctgtatttc tagattgtgt ttgcatcaag ttgcaataaa aactagaaat caaatcgggc
    28261 tgataatcat ttataactaa tcgatacata ggaccaaata taggtctatg ttcttttatt
    28321 tcataagtat cgtaaaacag aattttgcta tggattaatc caatcgactg atatgtttag
    28381 taaataaaga aagaggaatg tcaatgatga aaaaagaaat cgtattaaca gcagcaatga
    28441 tgttattcag catggtagca agtacgactt ttgtttctgc aactgaagta tacccaaagg
    28501 aatataacac agaaggaacg attacatttg aagcaggaga tgagggtgta actcctcctg
    28561 ttgatccaga gaatcctgat cccaataaac ctgtcgatcc atcagatcct ccaagccctg
    28621 gaacaggagg ggcattatcg attgattatg gatcaaaatt caaatttggg actcaaaaaa
    28681 tttctactgc ggataaaacg tattatgcag ctgctgatgt gatgaacgat gggtctagaa
    28741 aaccgacata tgtccaagtg acagatagga gaagtacctt atctgggtgg aaattaagtg
    28801 tctctcaacc agaacagttt aaaactgcca gtggggatga actagttgga gcacagctga
    28861 aatttacgaa agggcaggct gtttctttgg ttgatccaac atatacgccg caaacggtga
    28921 attctgaatt aacgttgaca ccgggaggaa acaatacgtt agcaattaat gctaaatcag
    28981 gaacaggtgt ggggacttgg gtctatcgat ttggtgcaaa tgaaaatgaa aatcaagatg
    29041 cggtacagct ttcggtaccc ggtaaatctg tcaagttagc gcaacaatat tccactaaat
    29101 tagtttggac attagaagat acacctaaca actagtttac tgaaaagaac tgttaaaaat
    29161 aaatacgtag tcatattgtc ttgcgaggta atcgagcaaa aattgtcaaa ggctaggcta
    29221 aatttgtttg gatacgaata gttcatctag gaatttaacg atcaggagga aaagatatat
    29281 tgaaaaagag gaggatcgtg ctcattttaa gcagtctctt agtgactaat atctttccga
    29341 tcatagggta ctctttggaa ttgaatcagt tggagcatgg aaatagaaga gacgaagaaa
    29401 gcaaactcac ttcgacattc gacagtttaa tagaatccaa ccagacacaa gaaagcagtg
    29461 aggatttaag tatttcgagt agtggagaga ccactgacaa cgtagaagct gagggttcgg
    29521 acaaacaagg actagaagat gcaccaattt ctgcggttga gctgcctgac gatcccaata
    29581 ttatttctat cgataaaatt tttcaaacac ctatcggtac tagcacgtcc atattggaaa
    29641 atgggaagtt actgcagttg aacccagcag aaaggtctca aagaggagct atttggtcaa
    29701 ataagaagat tagtttactc tcggatttta catttaaatc ttatttatac ttaggaaatc
    29761 aacgagatag agcgggagat ggcatgacct ttacattgac tggcgatcct agaatggcta
    29821 gtaatcccag tcaagttatt ggatcgccag gtatgggaat tggctcatat tctactcgtt
    29881 ctggccaacc ttacattgcg aatgcgctct cgattgagtt tgatacgtat aaaaatagtg
    29941 gttcttctga tcgaatggat cgagagataa ctgctgataa tagagggcat ggacatgtcg
    30001 cttttgtcac gcctaaacca aataataata attattctgg agagcatact ggcgtgacgg
    30061 tagctcctac atttctttct aatggcacat ggcgcttgtt aataattaaa tgggacgcgg
    30121 agcaaagaag tcttacttat gatttggaag gtgtcggtcg ctcttctcgg attatacctg
    30181 atctcattag gcagtttggt tctacagaag taaattgggg gtttacttct tcaacaggta
    30241 ctttttttca agaaaatgct gtcgctgtca cgcgacttcc atcgaatgtc acatcaacag
    30301 ctgatgtaaa agtcaacgat agtgattatg gggccatcgc tgaagctgga ggaaacgata
    30361 agataactat cagaaataca ttgaaggtcg agggggattt tcttgaatat aagaaaatgc
    30421 agactagtat cgacctccca caagaattaa ctattcccga gcatatcttg atcaatggaa
    30481 atcaaattga tgccaaagat atcttgataa ccggaaatcg agtcacgcta aatctgacag
    30541 attattttat tgctggagat acgttaataa tcgaattgga gacaactttg caggaagtaa
    30601 ttcctgaaaa agtactcact atgcattttg aataccttga aaacgggaat ttgattgagc
    30661 aatcgaatga aataaaccta aagatcgcaa agctgaagga gatagatatc catgtttatt
    30721 ataaagataa agacagtcag attgatattg ctgaaatgaa aacaatcact gggaaaatag
    30781 gagagaagta taaagaaact cctattgata ttgaagggta tgtttttgac tcggattcag
    30841 cgaatacaga aggcatcttc tccgaaaata cagaggatat ctatttttat tacagaaaag
    30901 gcaaacttta tctctcaact gctcctcaat atgtcaattt tggaaaacat aaaatatcca
    30961 gtagaccatt aagtgaattc ggacagtttt caggtgggtt gaaaattata gatgaacggg
    31021 cttttggaag ttggaaatta caattgaaac aagagaaagt tcttacaaat ggagattttg
    31081 agcttccaga agctctttcc tttgttacct ctgaaaatac aacggttata gggacatccg
    31141 ctgttacgat tttcgaaagt gatcaaaagg gtgaaagcga tttgtcctct cttttagatt
    31201 ctacagctca tcgtggaatc agaataaata ttcctgtaga aaaccaaaga atcggaacct
    31261 ttgaggggaa actatcttgg atacttgcag atgtcccagg aaattaacag gaagagaaga
    31321 atataacaaa attattgagt ttcaagaagg gcacaggtac cataggctct tgtgtcccac
    31381 agagacaaga ttttgttata gtcttctctt acatatgatt aaaggagcga ttttcttgag
    31441 accaaaacaa caattattta taacactcct agttatttta ggggcacttt ttaacaatat
    31501 atcagtgtca gctagtgcat ttaatttttc agtgacgccg ataacttcag agaatcaaat
    31561 cgacaagaga aaaacttact tcgatcttca acttgatccg gatcaggaag tagaagtaaa
    31621 agcggaattg agaaatgata cagaaaaaga agtgaaaatc gatatttctg tgaatagcgc
    31681 aaccaccaat tcaaatgtga tggttgaata cggaaaaaac gagattgaaa aagacatgag
    31741 cctgatcttt gatctggtag attatgtgag ctatccacag atagtgacgc taaaacctaa
    31801 aagtgtccaa accgttgctt ttcatgtcag gatgccgaat gagcgatttg atggtgtatt
    31861 ggctggtggg atcacattcc aagaaatcca gacggaaaag gaccaaacag aaactaagga
    31921 tcaaagctta tcgattgaga atgaatacac ctatattatt gctttgttga tgcaacagac
    31981 actgaacgaa gttgctccga accttactct tcatgaagtt aaaccagatc aaatcaatgc
    32041 aagaaatgtc atcttagcaa acgttcaaaa tgatcaaaaa acctatatca atcaagtagt
    32101 tattgaaaca aaaattacaa aaaaaggaca ttctgaagtt ttatatcaag aggaaaaaga
    32161 aggattgcag attgcgccga atacaaattt ttcttttcca actgctttaa atggtcaacc
    32221 gctaacccca ggtgaatatc accttacaat gactgtttta ggaaatgaaa atgaaaatgg
    32281 aaaattttcg agaaaaaaag gaaatactac gatcaactat accaatcaat gggtatttga
    32341 aaaagatttt acaatagacg gaaaagtagc caaggaattg aacacgacgg atgttacgat
    32401 taaaaaagac aataattgga tttatatctt agtagcttca cttttcttat tgtttatttt
    32461 attatgcata cttttgtttg ttttgagaaa aaaagaagag aaagaaaagt aaggttaaga
    32521 taacaaatag taaattttta ttattgtagg atggttgggc tctttttata acaatataaa
    32581 atataccatt ttattaataa aaatgcatac tagtaaatga tataattcta ataacaggtt
    32641 tgatcgcgag aaaggccaaa taaaacgctc tccaaaatgt taaaaaaaag acaggacgat
    32701 gtatattata caaacaagaa tcgctgacaa cagtgactcg gatccaggaa atcagtttta
    32761 tccccagcta gttggtgaat gcatggaaag taatatacgt agaaagagct gatgactaat
    32821 gaattatgag ttttttttaa gcaaagaaga tcacagaagt tattcattac ttaaatattt
    32881 agaagcaagc tcaaatttat cagagtcaat atcgaatgtt caagaagagt tgtcgctatc
    32941 gacatttctc ttgaaaaaaa cgatcgataa gctgaaacat gatttacaaa agttcgatct
    33001 agagaaaaat ttgcgagtaa ccgtcagtga attggatata tgtctggaaa ttaatggaaa
    33061 atgttctagc aaagctctgt tatctcgtta tataacggat tctttatcta tgaaaatggt
    33121 attggctttc tttcaggaaa aatatatctc agtagaaaat tttgctaaac agcatcacgt
    33181 gagttattct gtggcttata aagtattaca aagactaaaa agaaatctaa aaaaatatca
    33241 aatttttttt gaaaagagaa a
//
LOCUS       DAFLWC010000023        32605 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.023, whole genome shotgun sequence.
ACCESSION   DAFLWC010000023 DAFLWC010000000
VERSION     DAFLWC010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32605
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.023"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            114..683
                     /locus_tag="L1V17_001010"
     CDS             114..683
                     /locus_tag="L1V17_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1235794.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(861..1301)
                     /locus_tag="L1V17_001011"
     CDS             complement(861..1301)
                     /locus_tag="L1V17_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBN1235795.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            1459..2223
                     /gene="map"
                     /locus_tag="L1V17_001012"
     CDS             1459..2223
                     /gene="map"
                     /locus_tag="L1V17_001012"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBN1235796.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            2255..3178
                     /locus_tag="L1V17_001013"
     CDS             2255..3178
                     /locus_tag="L1V17_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBN1235797.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(3403..3642)
                     /locus_tag="L1V17_001014"
     CDS             complement(3403..3642)
                     /locus_tag="L1V17_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1235798.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(3647..4066)
                     /locus_tag="L1V17_001015"
     CDS             complement(3647..4066)
                     /locus_tag="L1V17_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBN1235799.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            complement(4293..5531)
                     /locus_tag="L1V17_001016"
     CDS             complement(4293..5531)
                     /locus_tag="L1V17_001016"
                     /inference="COORDINATES: protein motif:HMM:NF017760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1235800.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            complement(5638..6273)
                     /locus_tag="L1V17_001017"
     CDS             complement(5638..6273)
                     /locus_tag="L1V17_001017"
                     /inference="COORDINATES: protein motif:HMM:NF012655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1235801.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            complement(6615..7250)
                     /locus_tag="L1V17_001018"
     CDS             complement(6615..7250)
                     /locus_tag="L1V17_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1235802.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            7762..8904
                     /locus_tag="L1V17_001019"
     CDS             7762..8904
                     /locus_tag="L1V17_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBN1235803.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            8897..9103
                     /locus_tag="L1V17_001020"
     CDS             8897..9103
                     /locus_tag="L1V17_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBN1235804.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            9182..10375
                     /locus_tag="L1V17_001021"
     CDS             9182..10375
                     /locus_tag="L1V17_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1235805.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            10580..11719
                     /locus_tag="L1V17_001022"
     CDS             10580..11719
                     /locus_tag="L1V17_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HBN1235806.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            11712..12512
                     /locus_tag="L1V17_001023"
     CDS             11712..12512
                     /locus_tag="L1V17_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1235807.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            12512..13339
                     /locus_tag="L1V17_001024"
     CDS             12512..13339
                     /locus_tag="L1V17_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1235808.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            13317..14051
                     /locus_tag="L1V17_001025"
     CDS             13317..14051
                     /locus_tag="L1V17_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBN1235809.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            14151..15017
                     /gene="rfbA"
                     /locus_tag="L1V17_001026"
     CDS             14151..15017
                     /gene="rfbA"
                     /locus_tag="L1V17_001026"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBN1235810.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            15031..15603
                     /gene="rfbC"
                     /locus_tag="L1V17_001027"
     CDS             15031..15603
                     /gene="rfbC"
                     /locus_tag="L1V17_001027"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBN1235811.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            15625..16653
                     /gene="rfbB"
                     /locus_tag="L1V17_001028"
     CDS             15625..16653
                     /gene="rfbB"
                     /locus_tag="L1V17_001028"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBN1235812.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            16751..17602
                     /gene="rfbD"
                     /locus_tag="L1V17_001029"
     CDS             16751..17602
                     /gene="rfbD"
                     /locus_tag="L1V17_001029"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBN1235813.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            17636..19669
                     /locus_tag="L1V17_001030"
     CDS             17636..19669
                     /locus_tag="L1V17_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235814.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            19713..20993
                     /locus_tag="L1V17_001031"
     CDS             19713..20993
                     /locus_tag="L1V17_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HBN1235815.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            21203..22009
                     /locus_tag="L1V17_001032"
     CDS             21203..22009
                     /locus_tag="L1V17_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1235816.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            22021..23241
                     /locus_tag="L1V17_001033"
     CDS             22021..23241
                     /locus_tag="L1V17_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1235817.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            23231..24817
                     /locus_tag="L1V17_001034"
     CDS             23231..24817
                     /locus_tag="L1V17_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBN1235818.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            24856..26994
                     /locus_tag="L1V17_001035"
     CDS             24856..26994
                     /locus_tag="L1V17_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBN1235819.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(27362..28345)
                     /locus_tag="L1V17_001036"
     CDS             complement(27362..28345)
                     /locus_tag="L1V17_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HBN1235820.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            28723..30114
                     /locus_tag="L1V17_001037"
     CDS             28723..30114
                     /locus_tag="L1V17_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBN1235821.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            30130..31170
                     /locus_tag="L1V17_001038"
     CDS             30130..31170
                     /locus_tag="L1V17_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBN1235822.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            31189..32274
                     /locus_tag="L1V17_001039"
     CDS             31189..32274
                     /locus_tag="L1V17_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HBN1235823.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            32307..>32605
                     /locus_tag="L1V17_001040"
     CDS             32307..>32605
                     /locus_tag="L1V17_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBN1235824.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYP"
BASE COUNT        10651 a         5522 c         6438 g         9994 t
ORIGIN      
        1 atttcagctt gtgaagaaaa tcaaaaacta attttgcata tcaaaaaaaa catgttacaa
       61 tgaaattaat caatggtgga agcgttataa aaaaattaag gagattaaaa aatatggcaa
      121 gaaaaaagac gattactaga gaacagattt tggcagctgc ttatgaagta gctgccaccg
      181 atggatttac acgatttact gcgagaaaca tcgcgaacaa aatgaattgt tccacgcaac
      241 cgatttatct tgagtttaaa aatatggatg acttgagaca agctcttttt gagcagatct
      301 atgatcattt acaatatgaa gtgttcactg ttgagcatac agggaatacg attatcgatc
      361 ttgcttttaa ttatatccat tttgcaagaa gagagaagaa gttgtatcgt tcactgtact
      421 tagaagaata tggtggagga aaagagatgc agaatttctc ttatacttac tttgtgaata
      481 cagtgaaacg cgatccagct tatgtgaatc tttcagaaga gcagatcgaa tctttgtata
      541 atgggacatg gatcatagct actgggatcg cagctttgat gtcttcaagc atcatccatc
      601 caactgatga acagattgaa aagatgatcc aagacagtat agatgctatc ttgaaattca
      661 aagaaccaat cgaaatcgat tgaatatact caaaagttcc acaaatcagt aggtaacaag
      721 agatgtgtca aaataaggaa aagttcgttt ttcttacagc gtatgcattt ttaactcccg
      781 aagaactctt ccatgaatgc aatgaataaa agagccatac agattgaata aatctggatg
      841 gctcttttat tgcaagtata ttaaattttt gcgactagtt ctttagcgaa agcttctaaa
      901 ttttcgatat cttcttcttc agcattcaga tccactttaa cattttcggc tccttttgat
      961 gcgcctgttt ttgcaaaagc agcatcgaaa tcatccaccg atttgcagaa ttcatcgtaa
     1021 aaagtatcac cagatccgca gacaccgtaa atttttccca atagatccaa ttcttgcaag
     1081 tcttcataaa agtctacgat ctcatcaggc agatcgccat catcgtatgt ataagtagct
     1141 actacgcaaa tatctgcctc ctcgaattca tctgcatcta cttgggtaca ttcgttgatt
     1201 tcgacttcga tatccagatt ttcaaatgct tctgcaacaa tatcggcgat ttcttcagtg
     1261 tttcctgtca tgctagcata tacgattttt gctaaagcca tgatgtgcct cctcgtttat
     1321 aattatttaa caattatgaa ttataccaaa acatcattga aaagaaaata aaacctagag
     1381 acacctgggg aatgtcattt ggctaaatgt atgccgctat gttaaaatga gagggatttg
     1441 taaaaaggag acgaaaatat gattacttta aaatcagcac gtgaaattga aatgatggca
     1501 gaatctggag ctttattagc agatgtacat aaaaatctgc gtgattttat aaaaccagga
     1561 atcacaagtt gggatattga ggtatttgtc agaaactata tcgagagtca tggcggaatt
     1621 gctgcgcaaa ttggctttga agggtatgaa tatgcgactt gtatcagtat aaatgatgaa
     1681 atttgtcatg gattccctcg taaaaagcct ttgaaaaacg gtgatttggt aaaagtcgat
     1741 atgtgtatcg atttgaaagg cggcatttct gattcttgtt gggcctatgt agttggagaa
     1801 tctacacctg agatcgaccg attgatggaa gtaacgaaga aagctttgta catcggtatt
     1861 gagcaagcac aagtagggaa tcggattggt gacatcggtc atgctatcca aacttatgta
     1921 gaaggcgaaa atctagcgat cgttcgtgat tttattggtc atggcgttgg tcctacgatt
     1981 catgaagaac cagcagttcc tcattacgga gaagctggaa aagggttgcg gttgaaagaa
     2041 ggcatggtta tcacgatcga acctatggtt aataccggaa cttggaaaat gaaaatggat
     2101 cctaacggct ggactgcgta tacaagagac ggcggacttt cttgccaata tgaacataca
     2161 ttggctatta ctaaagatgg tccaagaatt ttgacatcac aaggagaaga aggcacttat
     2221 tgatctatcc agtcaatagg tacgggagag gtacatgaaa gtttggaaca aaataaaaca
     2281 aaatgaaaat ctgatgcgct ttattgagac gactcaaaag cgcatcactg attcagaaat
     2341 gagtacgacc tctgtcgtcg ttgcttatta tttactcttg tctttatttc cattgattat
     2401 tgcttttggt aatattttac cgtttctcca catcgatcaa gagactgtac tgacctattt
     2461 acgagaagtg attcctgaga ccgtttacca gtttatcggt cctgcaatca aagacctttt
     2521 gacacaaagt tcaggaggct tgttatccgt ttctgcatta gcggctttat ggtctgcaag
     2581 tcaaagtatc aatgctttgc aaattgcgat gaataaagcg tatggcgtag aaaatagaaa
     2641 aaattttttg atcgtccgtt tcttctcact aattgtcatt gtcttgttca tgattgctat
     2701 tagtggggta actatcgttc ttgggttggg acagctgatt ttggatgcta ttcagccaat
     2761 cgtacaaata cccgtgaact ttatcgatca gttccaaact ttgaagtggc caatcacatt
     2821 ggtagcttta tttgtcatca tgttcttgat ttatttaatt gtccctaatg ctcagttgaa
     2881 gttgaagacg atcattccgg gcacgatctt cgctactgtc ggctggatgc tgttatcaca
     2941 agtgtttagt atctatgcta ggtattttgc aacgaggatc agcggttatc agatcatagg
     3001 aagttttatt gtactcatgc tttggcttaa ttttgctgct acgatcatca ttttgggcgg
     3061 aatcatcaat gcagttgttc aagaatacgt gacgggtcat caaatcaaaa aacgtcgaga
     3121 tccaagccga aaatggttca ataaattgaa aactaaattt tctcataaaa aaaagtagaa
     3181 acaagagttc ttattgtaaa tttatatcag taatttattt gaaattttat atctaatttt
     3241 caattatccg cataaacact atacattcaa gcattttgaa gtatagaaaa acactcatct
     3301 taccacgaat ttaccacgat tgaatgagcc ttgatatgac cgtaaaacta ctaagggaga
     3361 tagcacgaaa ctgtgtatct cccgattttt ttatacagtt gattacttca ctccgatttc
     3421 aaatttcaat attgctttca tcatgtctgt atgaatttct ccttttagtt cttcatcaac
     3481 ctgcataatg attttaccac tttcagagtg gtaaaaagga cgcaagcata atttagaaat
     3541 ataaccgtca taaaacttca aaatctcttt aactgccatt tcatctccgc ttgacgcttt
     3601 gcaaatcaat tcaaaagagg gatagccata atctttactc atttctttac ttcctttcgc
     3661 tcaaaagcat ttttaacttc cttagtcctc tagttcttct actgcaaata gcagaacgtg
     3721 atacatggta cagttctgaa atttctctgt cgttcattcc ttgaaaataa cgtaataaaa
     3781 tcgcactacg ctgtttttct gacagtctat gtaaaactgt accaagtgtt tcatcagata
     3841 cataaattgt aaagtgcaag actttaaatg atacacaatc ataaaaacag gtatcaatcg
     3901 ttccacgttc aacttgtttc gtttcggcta tttcacaaaa caatacttca cgtttagaat
     3961 gtcttgcaag ctgtctgttt cgacttttca ctttgttctt aatgacaatc agcattaaag
     4021 aattgaactg taatctgacg atatgctcga aagaagatgt cctcataatc tcaccccctt
     4081 tctgctaatg ctgaaatata taaacggaat accgtttata ccctttagaa atacagaaaa
     4141 atggtaagaa aaaagcccac acaaaacata tatttgtgcg agccttaaat actgcaatat
     4201 tactctttct tttataacac tatcctttta gcagatttca aattttcttt tatatattgt
     4261 ttttagccta acatactatt taaccccttg tattatatct ctaacttttg aaaaattctt
     4321 tttgaatata ttgaaatcat gattgaagca atagaagcta caaacataac aacccatgtt
     4381 tcttgtataa atacatcgaa taaaataccg taaaccattt gtccaatagg ttgaccgcac
     4441 atagcaactg ctaccagcgt agccattatc tttcctacta attgcggtgg tgtttgtgtc
     4501 tgaacaagag tgtaaatttg aacaacaaac atagtagata cacccatagc cacaaagcac
     4561 atcactgtaa ctacccagta ggaaactatt gcaggcaatt ctaaaaatag cgaaattccc
     4621 ataagtaaaa cagaaacaga acaaataagt aacaaggtat aaaggttttt tagttttaac
     4681 tttgaagcaa caagagctgt taaaatacca ccacataaac cacctaatga taatgctgat
     4741 tgtgaaaaac catatagtgt atctggcatt tttaaaactt cagaaattaa gataggcaga
     4801 ccaacaatta aaacagcact taaaaccaaa ttgaaaatgc aaaccaaaaa gattacggat
     4861 ataaaaatgg gtttctcctt tttcaaaaag gtataactat cttttaaatc gtttttagca
     4921 actgcaatta cacctacttc acgaggtctt ttttggtgtg gaatatggat aaaaatttcc
     4981 ataatggctg aaaaagtaaa acatataata ctaacaatta aaatgggatt gataccataa
     5041 aattgaaaaa ctactccgct tatagctggt ccgataaagt ttgctaaagt atttacttga
     5101 tttattatag cattaccgac ggtaagttta tctgatgata ccaatagagg aatacttgct
     5161 tgtaccgctg gttgatatgc accagaaata ccataaagta acatcaaagc aacaataaac
     5221 aaaggtatga taggaatttt tcccaatgac aaataaaata ctaaaattat gattgctgtt
     5281 acaaaatcta gtatgaccat aatgtttctt ttatttgtcc tgtcagcaat aataccacct
     5341 accagcgaca aaataaccat aggtaaaaaa gagcaggctg tagcaatacc aaacaaagct
     5401 gatgaaccag tttcttttaa caaatagtac ggtaatgcaa atcgtaggat agcgtttcca
     5461 aataaagaaa ttatctgtcc tataacaaca agtataaaat cacgattaaa aagttttttt
     5521 tctgcttgca taaaatctct cctttttatt taatcaaaca gaccgtcggt ttatataatg
     5581 gtttaaataa actgctcttt tatagagcag tctatcgtat agggataaca aatacagtta
     5641 tttacaaaac tgtataaatg cagaaattgt ttcttcgtct aataatgtgt ctatgcctat
     5701 tccatttaaa agggcattga atgtattgca acgtttttcc ataccctctt tatccgtcat
     5761 ttcaactaat gggttgagcc atacattact taataccatg ataacttctg caatttcatg
     5821 tgaattttca atctccaaag acttatcctt gataccttgt tctaaaacgg gttcaacaaa
     5881 ttcaggtact acaatttcat acatttgttc tatttgcata gcaagaaaac gaggattgtt
     5941 taatagttga ggagaaactg tcaataaaac gctttggtta gaattgaata ccgctgtctt
     6001 aaatatttct cttaactttt ctaaaccgtt taaactatcg ttatctctaa ttttagcaaa
     6061 tattactgca ttttcatttc caattctttg aaaaattgct tttaaaatat cttcctttga
     6121 atcgaaatga tgataaatag cacctttaga aagttttgtt tcattgataa tatcttgcaa
     6181 tgatgtgtta tcatatcctt tttcacaaaa catttttgta gaaacatcta aaatgagttt
     6241 tactgtttct tctggatatt tatttcgtgc cataacttac ctccaataca aaccgttggt
     6301 ctgattaaag tatatcttag tattttatgc ttgtcaatat aaagacttgc aattttataa
     6361 aaatgcagaa tgcaagcctt tttcatttat tctacaatct tccagttgct ttccttatgc
     6421 ggtgtcaatt catactgtga tacctgcgtt gcctttgcct gatttaccac aaatcagatt
     6481 ttatcccttt cttcctcttg attgcccaca acagaaaaga aaaagccctg tcaagagctt
     6541 tgccaccatt ggtggtgctt tgcactcttg atcgggcttt ttgtttgctg tatcttctcg
     6601 caagaggaaa aaagttactc gtcctcatca tcaaaattgt tattccttaa tacttctcgt
     6661 aacagttcca tatcttcttt tgagttcggg tttatcattt tcacgacttg ataaggtgtc
     6721 ttatacttat gtccctctat gctttcccca aacatatcca tactgtataa atcatcatag
     6781 cggtctaata atttttgaaa cttcaaatgc tggataaatt ctttgattgg gtaaaggtcg
     6841 gacgcttcaa tgcttttccc gttgatatag tctgtaatat attcccgtaa cttttctaac
     6901 tcatattcca gccattcttc ctcgctgtca aagaagttat catagtgtcc atgtttcagt
     6961 tctgcattta gacgttcttc ggctcttaaa aactgacaga cttccttttc agattgattg
     7021 acatacttcc attctcccga caacaattca ttgggcgtaa cgtccagcac ttccattatc
     7081 ttttccagcg tttcataggc aggatagttc aaccctcttt caatcttgga aaggctctgc
     7141 atattgatac cgattttgtc cgcaagttcc tgttgtttca ttcccctaaa ttttcttatg
     7201 gtctgtatat tatttcctaa atggcttatt ttcattgcat aaccctccat atctcgttat
     7261 atcttcgcta ttataagtct atcatgctta atatgatttg taaaggcaaa aaaagatatt
     7321 gacaaataag catataagaa ttactatgtt cttgtaatcg aataagcaca atagaatgaa
     7381 atataaaaac attcaaaaag aaatacctat ctgattaaat ccgtagatat gaatatcggt
     7441 tgaaatggaa cttgttagaa aaggcaaaac agaacttgct gacaaagtat ttctgacacg
     7501 gtggcggaag cctctcaggc ttaccgccat gacaccttgt gtcaagggga agaaatgctt
     7561 tgtcggctgg cgagcctgcg agccttgtct gtgcccccgt tatctaacag gggggcacta
     7621 tttcacaaaa gacaagtcaa aaaccataca cccccaaacc tgtgagtagt aatgagaggt
     7681 tttaagaaga tagtacatat cacacttttt gaaaggtggt ttacaggtat ttcaaggcta
     7741 ttgtgggatt ggaggaatac aatgaacaat ttagaatttg cacttgaaat gaagaacaaa
     7801 cgtcttgcca gcggtctttc acaaggagaa cttgcaagtc ttacccatgt atcaagatat
     7861 agtatcaacc gctttgagaa cggaaaagct aacgccagca aggaaacaca gaacattatc
     7921 ctgcgttgtc tgaattacta tatctgcgat aagccttttt atctgctcgt tgattatctg
     7981 tctgtccgtt ttccaacgac tgacgcattg gaagttatcc gaaaggtgct tggcatgaaa
     8041 gcagattatt ttatccatta tgactatggg tattatggct ataaggagca ttatgcttac
     8101 ggggaaatca aggtcatggc ttctgatgat gaacacatgg gcgtattttt agaattaaaa
     8161 ggggcaggct cacgcaacat ggaatatgtc ttacaggcac agaacaggga ctggtattca
     8221 ttcttaaacc gctgtcttga ctgtggcggt gttatccgac gttttgactt ggcaatcaat
     8281 gatatgtgcg gtctgctgga tattcctgtg ctatctgaaa aatacagaaa tggtggtgcg
     8341 gaatgtcgct gtaaaaacta tgaaaatgta caaggtggaa aattaagcgg aaaaaaccgt
     8401 aatttagcaa gtacccttta tatcggctca aaggcaagca caaaatattt ctgcctgtat
     8461 gaaaaacaaa aggaacaggc aacgaaaaag aaacataccg atattatcaa ccgttttgaa
     8521 attcgtctgc gtgacaaaaa ggcggtacag gcagttgaag aactgttatt gacgtataac
     8581 cctcatgggc tggtgtttta tctcattacc gattttgtgg aatttcctga ctatccattg
     8641 tgggagatat tcatttccca tgacagttta ccttttgaaa tgaaccctgt acctgtcaat
     8701 atggaacgca ctctgcaatg gctggaaaga caggtcatgc cgtcaatcgt gatgatagag
     8761 gaaatcgaca ggctgacagg ttcaaactac atgaaaatga ttgatgaatg tacccacctt
     8821 tctgaaaaac aggaaatgct tgtggaacag atgtgtacgg acatatcaga cgtaatcgaa
     8881 agtgaggggg tgttttatga gtaatacaca ggatattccc gtatgggaaa aatacaccct
     8941 taccattgaa gaagcgtcaa agtatttccg cattggagaa aacaagttaa gacgattggc
     9001 agaggaaaac aaggacgctg gctggctcat tatgaatggc aaccgcatac agattaaacg
     9061 ccgacagttt gaaaaggtta ttgataaatt ggacgcaatc taatgcaaat gagccttgta
     9121 tgtgttatga tgaacacaag tcatatcaag gctctttcca acaaggaaag gagcagacac
     9181 catgaaagaa aaaagacggg ataacaaagg tcgtatcctg catactggag agagccaacg
     9241 aacagacgga aaatacttat ataaatatgt agacgcattg ggaaacacaa aatatgtgta
     9301 tgcttggaga ttgacaccca cagacccgac accaaaggga aaacgggaaa aaccctcact
     9361 tcgagaactg gaacagcaga taagacggga tattgaggac ggtatcgaca gcacaggcaa
     9421 gaaaatgacg ctttgccaac tctatgccaa acagaacgca cagaggacaa atgtgaagaa
     9481 aagcacacag aaacaacggg aacaactcat gcggttatta aaagaggaca agttaggtgc
     9541 taggagcatt gatacgataa aaccctctga cgctaaagaa tgggcgttac gcatgaaaga
     9601 caaaggcttt tcctacaata ccattaacaa ccataaacgc tcgttaaaag cgtcattcta
     9661 catagccata caagatgatt atgtgaggaa aaaccctttt gatttcaagc taagtgaagt
     9721 catagaaaat gataccaaag agaaagtcgc attgacagag gaacaggagc aagccttatt
     9781 gtcatttatt aagacggaca acgtgtatca caagcattat gatgatgtgc tgatactgtt
     9841 aaagacagga cttcgtatct cggaactgtg cggactgaca gtagccgaca ttgatttcaa
     9901 gaatgaagtt gtgattatcg accaccagtt actaaagagt aaggaacagg gctattatat
     9961 tgaaacgcct aagacgaaaa gcgggataag gcaagtgcca ttaagcaaag aaacgataca
    10021 ggcatttcaa cgggttatca acagccgacc aaagataaag tcgatagagg tagacggaca
    10081 cagcggtttt gtgtttatca atccgaaagg taatccaaaa gttgccattg attataacgc
    10141 cttatttatc cgtatggtaa agaaatacaa caagcaccac aaggacaatc ccttgccaca
    10201 tattacaccg catacgctac gccatacatt ctgcacaagg ctggcaagca agaacatgaa
    10261 cccgaaagat ttacagtata tcatggggca ttcaaacatc agtatcacaa tgaactggta
    10321 cgctcatgcg tccatagata ccgcaaaatc agaggttcag cgtctaatcg catagaagta
    10381 tttaccacga ttttaaccac gattgacagg gaaaatataa gaagatagac ctagatatgc
    10441 gaggtttacc acaaaagcaa aatgcccgta gagccgataa aataaggctt tgcggacatt
    10501 tgagaagata taaaaagata gtcaaaaaga catatataat ttataataat tatgactctt
    10561 aattaaagta ggtgcccata tgcttgtttc ttttagtatg gttataagat tttttctgac
    10621 aattttatta tcactgatat taacacctgt attcaaaatc atttcagtac aaacaggtat
    10681 ggtcgacaaa ccaaatgaaa gaagaataaa taaagttcca atgccttcag cgggcggact
    10741 gcctatcttt atttcatttg ttatatcgac tttattctta ttccgtaaaa ttatccctca
    10801 atcgtatatt gtaccgatct tgattgcttc tttagtaatc atagtcacag gagtgctcga
    10861 tgataaatat gagctgacac ctaaacaaaa aagtataggg atcttgattg cttctcttat
    10921 tatttatttt gtagcagata tacgtattga ttccttcacg cttcctttta ttggatatat
    10981 ccaactaggc tggcttagtt ttcccgtaac gattttttgg atcttcggta tcacgaatgc
    11041 ggtcaatctg attgacggtt tggatgggct ggcggcaggg atttcattga tcggtttaat
    11101 tacgatagga atcattggat attttttcct ccatgcttct acagtgtata ttccagttgt
    11161 tattttctgt cttgtagcaa gtattatcgg tttttttcct tacaattttt atccggcaaa
    11221 gatttattta ggcgatacag gagctctatt cctagggttt atgatggccg tcctttcact
    11281 acaagggctg aagaacgtga cttttgtttc atcgatttct ttgctgatcg tcatgggagt
    11341 gccggtaaca gacacgtttt ttgctatcat taggagaaaa gcaaaccgtg tttctttttc
    11401 tacagcagat aaaaaacatc ttcatcaccg actaatcagt ttaggcttta ctcataaagg
    11461 tgctgtcctg acgatttatg cgatggcttt gatgttttct ttcacagcta tggtcatgaa
    11521 ttatactgga agaatcggaa cgatcatatt gattattgcc atgttgtttg ctgcaatttt
    11581 attatttgaa ttgattggtc tgatcaatga gaaacatcag tttattttaa aaacattgcg
    11641 atttttaggg aataaagagt accgtacgca agtaaaacag aaatatttga agaaatggaa
    11701 ccgtcatata gatgaataac aaattaaacc agccgatcct tattagtatt gtgacggcaa
    11761 acagtgataa aatttttcgg acactagata attttatttc aactgtaaaa gatgaaacag
    11821 cagtaaaaat ccgaattttt gacaacaatt cacttcccga gtacaaaaaa agactaacag
    11881 agtataggaa atatccctac atcgatatct attttcatga tgaaaattcc ggatttggtt
    11941 atggacataa tcacaatctg atagctagcg attctcgcta tggcattatt tgtaacccag
    12001 atattttagt ggatgaagag acagttacag cattggtctt gttattgaaa gaacatccgg
    12061 aatgtgcgat gttagcacct aagattctta atgaagatgg aacaactcag cacctcatcc
    12121 gtgagcagct ggctgttttt gattacgttt tgcgctttgt gcctttcaaa tgggtcaaaa
    12181 aaaagtttga caaacgactg gctgtgtttg aatgccgagg attgcctact gatgctaata
    12241 gttatgtacg gatgatctca ggtagtttta tggtagctga tattgataaa tttaaagaga
    12301 taaaggggtt tgatgagcgt ttcttcatgt actttgaaga caacgacttg tgtttgagtt
    12361 ttgaaaaagc aggttacaag ttattgtaca caccctttta tgcagttatc catttttacg
    12421 ggaagggtgc gcatcgaaat gcaaaactgt ttcgcgtgtt tttgacttct atgatgaaat
    12481 ttttcaataa gtgggggtgg cgttttttct gatgaaacca gaaatattag tagtcgttgt
    12541 gctttatcag caactattca gtcaatctcc agcttatgga ccattaagca aagcacttag
    12601 cgaaaagcaa attcagctta ttatttacga taatagtcct caaaggcagc aaaatgagct
    12661 gtttgaaaaa gaaaatatcg tttatcatca tgatccgcaa aatcctggtt tagcggtggc
    12721 ttataatttt gcgttgtctc aagcagatga aggaacacgt tgtctcgtca ctctggatca
    12781 ggatacgagg ctagtcgacg attattttga actattgcgt aaagtaacct ttacagatga
    12841 atgtgttgct gcagttccga tgattttttc tgggagccga caagtttctc ccctatattc
    12901 agatcgttat atcaatcgta cagctcaagc agtagaagtt gaaggcccaa cagctgaacg
    12961 aatcatggca atcaattcag gtgttgcctg gtctgtcaaa tttctaaaaa agattggcgg
    13021 gtttaatcct gctttttctt tagatttttt ggatcattgg ctgttttgga aagtggatca
    13081 gttggaaaaa actgtggaga tccttcctgt acgaatggaa catgatcttt cggttttaga
    13141 ctatgaaaaa gtttcaagta atcgataccg ttctatttta caagcagaaa atcgatttta
    13201 tcatgaatat gatcaaaggc atttatccag tcaccgacga caattattgt taagaacagc
    13261 taaacagttc ttgaccgtca aaaaccggca tatctggcgg atgactttgc gctcatatgt
    13321 taagaattgg aaggtgtgaa ttcgtgcgtt cggtttgtat agctaccttt aatggaggca
    13381 gatatttaag agagcagtta gatagtattt tatctcagct ttcagcagaa gatgaagtag
    13441 tcatttctga tgatgggtca gtagatgata catgggatat attaactgaa tacgcagaaa
    13501 aagataagcg aatccagctt ttttcggggc ctcgtcaagg attgatcgct aattttggtt
    13561 atgcgatcca gcagacgaaa ggagatctaa tctttttggc agaccaagat gatgtttggt
    13621 tggagacaaa agtgaaaaag atcactgact attttgagca gaatccggat cagctagtag
    13681 tagtttctga tttaatcatt gtggacagcg agctgcaaga gatccatgat tcgtattttt
    13741 cgtttcgaaa ttccaaagaa ggatggctta ataatgtgat aagaagtcac tatattggtg
    13801 ctggtatggc tttccggtct tctttaaaac ccgatatttt gccgatcccg tcagaagtgc
    13861 cgatgcatga tatgtggatt ggtttgctgg gaggaaagaa gactgggttc ctaagagaac
    13921 cgttaactct gtaccgaaga catgatttaa acgcgagtga gattgaaaca cattctaaat
    13981 tacggcaaaa aatttcttgg cgtgttcatc tgattacggc gttgatcaaa cgaaaatggt
    14041 ttaaacgttg ataaaagatg tttaaatcct taatatttcc atgacaaata taacaattga
    14101 tgagataata acaaagtgaa atttgaaatc aaaaaggaga gcagatatcc atgaagggaa
    14161 tcattcttgc tgggggcagc ggaacacgtc tgtacccttt aacaaaggca acatcgaaac
    14221 aattgatgcc gatttatgac aaaccaatga tttattatcc aatgtctact ctgatgttgg
    14281 cgggaatcaa agaaattctg attatttcaa cgccacaaga tacaccacgt ttcaaggaat
    14341 tatttggaaa cggaaatgat ttaggactgc agatcgaata tgcagtacaa gaaagtccag
    14401 atggattggc acaagcgttt atcattggag aagaatttat tggagatgat agtgtctgct
    14461 tggtattagg ggacaatatt tactatggtg gcggtctgtc taaaatgttg caacgagcag
    14521 cttcaaaaga tacaggcgcg acagtatttg gctatcatgt caatgatcca gaacgctttg
    14581 gtgtagtaga atttgatgag aatatgcaag ctttgtcgat tgaagaaaag cctgctcagc
    14641 caaaatcaaa ttacgctgta actggccttt atttttatga caatgaggta atttctatcg
    14701 ctaaaggtat caaaccttca gaacgtggag aactagagat tacggatgtc aataaagcat
    14761 atttggataa aggaaaacta tccgtagaac ttatgggacg cggatttgct tggcttgata
    14821 caggaacaca tgaatcattg cttgaagcat ctacctttat cgaaacaatt gaaaaacgtc
    14881 agaacttaaa agtggcttgt ttggaagaaa ttgcttaccg tatgggctac atcgataagg
    14941 aacaattgct ggcccttgca cagccattga aaaaaaatca atacggtcaa tatttattga
    15001 atttggccgc tgaataagga gtccttacag atgaaagtaa cagatacaaa attaacagat
    15061 gtcaaaatcg tagaaatgga cgtctttggc gatcatcgcg gtttcttcac agaaagttat
    15121 tcaaaagcaa aatttgcaga acatggattg aaatatgact ttgttcaaga caaccattca
    15181 ctatcagctg aagctggtgt ccttcggggg cttcatttcc aaaaaggaga agctgcacag
    15241 acaaaattga ttcgggtagt cactggagca gttttagatg tagtagtgga tatccgcaaa
    15301 ggtagcccga cttatggtca atgggacgga tttatcttat ctgaacataa tcatcgacag
    15361 ttgcttgtac ctaaaggata tgcccatgga ttcgttactt tgacaccaaa tgtgaacttc
    15421 ctttataagt gtgataatta ctataatgca gaagcagatg ggggcatcgc atttgatgat
    15481 ccagatttag cgattgattg gccaattgat ccatcaagag cgattatgtc ggaaaaagat
    15541 caccgtcatc cgacattaaa agaatttgaa gcagaaaatc catttgttta cggagaaatc
    15601 taagaattaa ggagaaattt tcttatgaaa aacatcattg ttaccggagg tgccggattc
    15661 atcggctcta atttcgttca ttacgtggta aacaatcatc cagaagtgca tgtcactgtt
    15721 ttggataaac tgacttatgc aggaaacaaa gagaacttgg ctggacttcc tagcgatcgc
    15781 gtagaattgg tcgtaggaga tgttgcagat gcagaattag tggaccgtct agtaaaagaa
    15841 gcggacgcag ttgttcatta cgcggcagaa tcccataacg ataattcatt aaaagatcct
    15901 ttcccatttg tacaaacgaa tatcattggt acgtatacac ttttagaagc ttgccgcaag
    15961 tatgatgtac gctatcatca cgtatctact gacgaggttt acggcgatct tccattacgt
    16021 gaagacctgc caggacatgg ggaaggcgaa ggagaaaaat tcactgcgga aacaccatat
    16081 aatccttcaa gtccatattc ttctacaaaa gctggttcag atctgttagt aaaagcatgg
    16141 gtgcgttctt ttggcttacg tgcaaccatt tcaaactgtt caaacaacta tggtccttat
    16201 cagcatattg aaaaatttat tcctcgccaa gtaacgaata tcttaagcgg tattcgtcca
    16261 aaattatatg gcgaaggaaa gaatgttcgt gactggatcc atacgaatga tcattcttca
    16321 gcagtgtggc tgattttgac gaaaggcaga attggcgaaa cctatctgat cggtgcagac
    16381 ggtgaagaag ataataagac cgtgatggaa ttgatcttag aaatgatggg tcaaccaaaa
    16441 gatgcgtacg accatgtaaa cgaccgtgca ggacacgact tgcgttatgc aatcgattcg
    16501 acaaaattac gggaagagtt aggatggaag cctgagttta cgaacttccg tgatgggttg
    16561 gctgacacga tcaaatggta cgaagaacat gaagactggt ggaaaaaaga aaaagaggcc
    16621 gttgaagcag catatgccaa aaatggacaa taatacagag aaaatgtcac tgtattaatg
    16681 gaaaaacaca tgtgaggcag gcgctcgcct gtctcttttt taaaataaaa atcaaggagc
    16741 ggataatcat atgtttttat taactggagg aaatgggcaa ctaggtacag aattgcgcca
    16801 tttattagat gaaaaaaatc tgcaatatgt ttcaacagat gcaaaagact tggatatcac
    16861 agatgccgag aaaacaatgg cttacatcac agaattaaaa cctgatgtta ttttccattg
    16921 tgcagcttac acagcagtag ataaagcaga agaagaagca aaagaattag atgagaagat
    16981 caatgttgat ggtacaagaa atgtagcact tgcagcaaaa gctgtgaatg ctcaattcgt
    17041 ctatatcagt acagactatg ttttcgatgg aaaaaacaaa aatgtagaat acgaagtaga
    17101 cgaccaaacg aatccactaa atgaatatgg tcgtacgaaa ttattaggcg aaaaagcagt
    17161 agaagagatt ttagaagact attatatcat acgaacttct tgggttttcg ggatctatgg
    17221 acacaatttc gtcttcacga tgcaacgcct agcggaaacc cgcgacaaac tgactgtagt
    17281 aaatgaccag tttgggcgac caacttggac acgtactttg gcagaattta tggtatatgt
    17341 catcgaagaa aaagcaccat ttggtattta tcatttgtcg aacgaaaata gctgttcttg
    17401 gtatgaattc gcaaaagaaa tattgaaaga tacagatgta gaagttgcac ctgttacgtc
    17461 agaagaattt ccgcaaaaag caacacgtcc gcagtattca gtcatgagcc tgaaaaagac
    17521 agaagagtta ggatttgtca taccaacttg gcaagaagca cttgcgcaaa tgctggaagc
    17581 tgccaaaaaa atgaataagt aatttccttt tatcaaatag aatttggagc atgatatgga
    17641 aaaacaaaca agaagtgcac gacgaaaaga aaagccaaaa gcgaaccagg cagattcgaa
    17701 tttggtgctt gacctgtttc taaaactccg ctatcttatt ggcgttttag tcatcgtggt
    17761 catcgttact tttaatttaa acggaagttc acttggtgtt tgggataaat atgtgtcgca
    17821 aagagacgat gggaaaaaaa ctgatgtgat ttttggacag aatcgggaag tgcggtcaga
    17881 cgaatggctg gtgcagacac ctttttacct ctcacaagct gaagaggact ttccgttggt
    17941 gaacgaggat tattcattaa acggacaaaa catgatcatt gcgtataatt ctcctgtaaa
    18001 ggatattacg gttatcggaa aaccattcaa ctggggattc tttttcctcg gaagagatcg
    18061 aggactttcc ttttattggg cgatgaaatt agtcgtcatg gtcttgcttg gattcgaagt
    18121 actgatgata ttaacgaaga gaaaaaaagc tctatcgcta atcggtgcat ttgcgctgac
    18181 attttctcca gcagtccagt ggtggttcat gcaacatgtg ggcgatttga ttttctttac
    18241 tttgggactg atgactgctt tttatcatta tttctacaat catgataaaa aatggctacg
    18301 aacgttgatg atgcttttgg tggttatttt cggtattggg tttattttag tgatttaccc
    18361 agcccatcaa gtgatgctgg cgtacttgct gattttttat tttgttggcc tgcttattta
    18421 ctatagcaag aaagtttcat gggatctgtt ggatgtagtg ttgattggag gggcagtttt
    18481 atttattggc ggagtcatgg ttcatttctg gctaacgtca aaagacgcat tgttagcttc
    18541 tttgaatacc ttatatccag gaaaacgggt aagtactgga ggaaagtgga cgattggcga
    18601 atttttttct ttccttacaa attggaaaat tccttttgaa gatatcaact attcgaataa
    18661 ctctgaagtg gccctgttct atcacttttt tccaactgta ttcctagcaa gtccatttgt
    18721 gttatttggc aaaaaagata gcgaacaaaa gttactggga cgtattttga tgattttttg
    18781 tctgttttct atcttttgga ttaccgttgg gttgccaaaa tggctagcag aaatcactct
    18841 gctgtcttat gttcctccat taagagccat ccttactttt agttttgcgg cttgtttatt
    18901 atcgatctgg tttatcgctt atatttggag agaagatgtt attcctattt ggtataaatt
    18961 cattttgttg gcagtaaatg catggtctta tttctatgcg attacgcatt cgaaaatgga
    19021 taattatttt tcggattttg aaaccatcgc agttgctgtg ttgggaacag tgattttagc
    19081 ttttgcatta tttggctgga gacgcttgtt ttacctcgct tttgccgcct tagttatcgt
    19141 atctggcttt ttcgtcaatc cagtcgtaga aggtacagga gcgatttttg aaaaaacact
    19201 ggcaaaagaa atccaaaaaa tcgatcaaca agatcctggt aaagtttggt tgtctgaaga
    19261 tgaattatat aacttcaccc caacattggg agtgaaatcc ttcaatacag tacgctttta
    19321 tccagatata gctgcatgga agaaaatcga tccgaaagaa gaatacgaga agtattataa
    19381 tcggtatgct catacaagag cttttatcgc taaggaagat acaaagttca ttttagatcg
    19441 tccagatatg ttttcggtca cgttgaattt tgaagacgca gaaaaattag ggatcgacta
    19501 tgtgatcagt aaacgaccat taactgatta caaccaatta tatgaagcgc agttcacgca
    19561 gctatatgga ccggataaag acggttatat gatttttaaa gtagaatatc cggattatcc
    19621 agatgtacca caaacacaaa ctcaggaaaa tcagctagtc gtacagtaat aggctagctg
    19681 agaataatcc tgaaatgtta gtagaaagga gagtggagat aattcaagca atcgtacaaa
    19741 aatttgtcaa caaaatgagt gtcggtttct tgcttttgtt actgacgcta gtcttttttg
    19801 tttggacagc agggttaggt tttccagcaa ctttgtttat atataacaat agttcattac
    19861 ttatcgcttt tagtgtggct attttgctca ttttaaatgt ttataaagca aaaggcgtcg
    19921 attttcttta tctaggtgtt gcgcttgccc ttttcatttt cttttcttac tttcgggaat
    19981 taagaaatga gtctttattt ggagacttac tgtttccttt gattatttta ttttgtttag
    20041 taattaaatg gatcgagtgg acaaaatggg atcgcggtat ttatctgatt gtcttttcgg
    20101 tcttcctcgg aatcacgtta tatcgtgtat ttacagagat ccaagtacca gaaggacaaa
    20161 gcatctgggc tccaggcaat tcgctttctg atatttggat caatacgaat ataatcggaa
    20221 gttctttgat gactcttgct ttattgatca gtggatttgc cagttctttt gaacgatggt
    20281 atgtacgaat catcggtgca gtagcagttg ttgcagcttt tctcgggatt tgggtctgcc
    20341 aatctagagg tgcattagtc gcgttgattg tttttgcgat attggatctt ttacctaaat
    20401 cgttgatgcg tgtcattcgt gcgccattta ttgcttacac ggttacgatt cttttagctt
    20461 tgccgatttc ttatctggcg gctgtctctg aaaaagtcaa tttgtttacc ggtcgagaag
    20521 atatttggca taaattctat cagacgctag gagaaaaatc tgaacaaatt ttactaggaa
    20581 tgaaaacatt tatcttccaa cgaggaaacc aatttttagg aaaccacaat agttataatt
    20641 ctattttgaa tatctatgga ttgataggat ttgggattgc tgctttgctg cttatccttt
    20701 ttattggtcg cttaacgttg aaagcagatt tatccaacgg gcagatgact tttatctggg
    20761 ccttttttgc ggtgatgatg cagtcattta tggaggatac attgacttca tacccatggg
    20821 ttccgattat ttatatcctg ttggctatgg ccgttcatcg atatgatgaa ccagaagttg
    20881 cggaggaatt ctatgttatg gaagaggcat atgacgatat gacttatgat gatacatctt
    20941 atgaggaaca accagatagc gctcattctt ccaggatcca acgctatcat tgataggcac
    21001 aaaatacgag agaggctgtg acaaccgtcg cagccttttt tggtttattg caattgtcta
    21061 gcatcttctg taaaatagaa acgttagaga aaatcttgta tcatagaaaa ttaagaaaga
    21121 aataagaacg cagctcggta ccaaaaatat ggtaaaatgg cacttgactg taattcactg
    21181 aaaatcgctt ggaggaacac aaatgtttaa agatttgtat ttatttatga aggacattta
    21241 tcagaacaga aaattattgc tacagttttc gatcaatgac ttcaaatcaa gatatgcagg
    21301 atcgttttta ggaatcttat gggcgtttat caatccgcta tttactgtat tgatttattg
    21361 gctggtattt ggtgttggac tgaaagcaca aatgatcgat gcaaaatacc catttatcgt
    21421 atatttagtt accgggatga ttccctggtt cttcttctca gatgcatttg catcaactac
    21481 ggttgttttt cgggaatata cttatttagt aaagaaagtc gtattcaata ttcgtatctt
    21541 gcccacgacg aaaatcctat ccaatctgta cacccactta ttcttcattc tgattggcat
    21601 agctgtcgcg cttataaatg gtatatatcc ttcagcaatg tctttacagc tgatttatta
    21661 tttattttgc atgtgtgctt tcttgacagg attgacttgg ctgacggcat cgatccaacc
    21721 atttttacct gatatcatgc aattaattac gatcgtgctg cagttgatca tgtggacatt
    21781 accgatatta tggagcccta atcagtttga ttcaggtctt gtaagcatat tgaaattaaa
    21841 tccgctgtac tatgttgttc aaggttatcg tgagtcattt ttaagtgaag cttggttctg
    21901 ggagcatgga acatatactt tgtatttctg ggttttcacg ttagtaatgt tcgtaatcgg
    21961 ctctgcagtg ttccgtagat tgaaaccaca tttttcagat gtgctgtaag gagaatagct
    22021 atgacagaat atgcaattag actaaaagat atcacaaaat cttataatat gtacgcaaaa
    22081 ccttcggatc gatttcgtga agccctcaat ccttttaaga aatcctatca tgatgtattt
    22141 tatgcgttga aaaacgtgaa tgtagaaata aaaaaaggtg agatgatcgg tttcgtggga
    22201 gaaaacggat cgggaaaatc tacaatgttg aaaatcatta cgggagtact gacaccaaca
    22261 tccggcacga tggaaatcga aggaaaaatc tcagctttgc tagaactagg atcaggattc
    22321 aatcctgagt attctggcta tgaaaatatc tatttaaatg gaatggttct aggattttca
    22381 agagaagaag tcgatgaaat ggtcgatgat atcattgaat ttgctgacat cggagaccat
    22441 atttatcaac ctgtaaaaac ttattcaagc gggatgttcg ttcgtctagc ttttgctgta
    22501 gcaatcaatg tgaatcccga tattttgatt gtggatgaag cattggcagt aggcgatctt
    22561 gaatttcaac taaaatgtat ggaaaaattt acagaaatca agaactcggg aaagacgatt
    22621 ttattcgttt ctcatgatat cagttcgatt cgtcgttttt gtgatcgttc ctattggttg
    22681 aaaaacggag aagtcgtcga atatggcgat acgatggaag taacgacgaa ttatgaaaac
    22741 tttttaaaga aaaaatcagt taaaacagtg gatcggaata aaaaccaagt agaacggttc
    22801 gccgctccag atatcgtcga cgtgacgaaa gcggaattgt tggataaaga caaaaatccg
    22861 gtggatatgc tggaacaagg agaaaaacta tacgttaaag taacttatga agtaaaagat
    22921 gatacaatca aaaatccggt tttaggaatt gcgctacgaa cagtcgacaa tttttatgta
    22981 tgcggactta atactctact agatggtatc aagattcctt ggaaaaaagg agagaatatc
    23041 ttttatctgg agtatgaaaa gttaggtttg ttagctggtg aatattattt tgacgttgcg
    23101 gtctttgaag aaaatgcaac ggttcctttg gtatataaga caaagtacat gaacttgttt
    23161 gtcagcggtt cttatatcgg agaaggcatc gtggtcttag accataaatg ggaagaaggg
    23221 actcatagca atgaaatatg attttgaaat ggacctagat gaacaaagca gtgtgggaaa
    23281 aattgccgca cagatcaaac caggaagtaa agttttagag tttggtcccg gaaacggccg
    23341 attaacgaaa catttaatcg gagcaaaaca atgtgaagtg agcattgttg agttagataa
    23401 ggaattgttc gattttgtca gcgaatttgc tcaagatgga ttttatggtg atatcgaaag
    23461 ttttgagtgg gcaaactatt atgctggaca gacatttgat tacgtcttgt ttgcggatgt
    23521 tttagaacat ttggtagatc ctggaaaaac attgaagaaa gtcagagaat ttttgaatga
    23581 agaaggagag atcctgatta cattccctaa cttggcgcat aattctgtca tgatcgattt
    23641 gttcaataac caattgccgt gggcttctta tggtctccta gatgaaaccc ataattcttt
    23701 ttatactcat gatggcttcc aaaaagtttt tgaaaaagcg ggattattca ttaatattga
    23761 agattatttg tacttagctg taggtgatac agaattaaaa tcaacttatg aagaattgcc
    23821 ggaagctgta cgctatgatt tcaaaatgcg accatttggt gaagtctacc aatacttttt
    23881 ctcattgatg aaacatccag tagcacaaag ttccattgca gagccacaaa attctaatta
    23941 tgtaaaagtg ttagaagtaa cccagcaaac gaaacaagat gaaacaatcc aacaaatacc
    24001 attcaataat ttcacagggg aaaatgagac actaagtttc cccgtatcag aaacaacaga
    24061 aagaatggtg tttcgcttcg cgcaacaacc tagctttatc gaattcagcg cagaagctgc
    24121 cggagaaaaa ctaacattta tcgattcgaa tgctgtagtc aaaacagtaa atgattgtta
    24181 tttgtttgat gggaaagaat taccagagtt cgttctaacg gatatttctg ggaaagaagt
    24241 gactatccat tgtcactatc gctttatcgg ggaattgaca ccaacaatga aagaattgtt
    24301 ggaaacgatt cgtcccatgg ctgaagtcac aaagcagctt tctgagaaaa atgacgaatt
    24361 agaaagagaa aatcatcatc ttcttgagga aaatacaaga ctagaccata cgttaaaaac
    24421 aaccacaaat cgctattgca cattgttgga aagtgatgaa tggacaataa aacatagact
    24481 aggacgacgt aagaaagaaa cttcgaaaaa aatccaagaa aaagaacttt ctatatgtat
    24541 tgacgagaaa atctgggatg cagaaacaaa aatattaaaa atcatcggat ggggaatcgc
    24601 taattcggat cgccagccct tgtcctataa gttatcagct gaccaatcgc catttttcga
    24661 agcaattcct gtttcacgag aagaagtcaa tcaagcagaa cagctcgcaa aaggaacaga
    24721 agcgggattt gagttacgaa tcctttgcga gcaagaacgt tcattcttag tggaagcagt
    24781 agctcaaaat ggccaatcat ggatcattga aatgtaaata atgattaact tataaagata
    24841 aggagtaaac gaatcgtgca aaaaaaagaa attgccgtat ttatcgatca aatcactcgt
    24901 gaacgggcca ctggcgattt gcttattgtg ggctgggcaa ttgatgaagt gaccaaagaa
    24961 atccctacga taaaggtaga aaaagaaaat gtgattgctg aagcaacaca tgtcgtaaga
    25021 ttggatatca atcatttata taatcttgat gttaagaccc aaagcggttt taaggtacgt
    25081 ttatcaggga aaatgagagg aaaagccatc ttagacttcc aaacagcgag acatcaaaat
    25141 ggcatagctg tgaaattaaa cggtaaatac ccttatgatg acggcattga atcttcatgg
    25201 gaaagaaaaa aaagattact gaaaaaaggg ataaattatg caaggactca tggcgtaaaa
    25261 aaagcgatcc gtcgggtcaa attggaattg aagccaggat cgatcgacta tgcagagtgg
    25321 atcagtcgtc atgagaaacc agatttgaaa gagcaaagga aagaagcaca aggatttgcg
    25381 taccgtccat tgatttccat acttatgcct gtctataacg ttgaaatcaa atggctcgaa
    25441 aaatgcattg attcggtact ggatcaaacg tatgatcatt gggaactatg tatcagtgat
    25501 gatgcttcta ctgatccagc tatccgaaag tgtctggaat cctatcaagc aaaagatgat
    25561 agaatcaaag tcgttttccg aaaagaaaat ggacacatca gtctggcaac taattctgca
    25621 ttggaaatag cagaaggaga atttatagca ctcttagata atgatgatga attaccgcca
    25681 tttgcattat atgaagtggc aaaagtgcta aacgtacatc cagaactgga tgtgatctac
    25741 agtgacgaag ataaaatcga tgcagatggc aatcgctttg atccgcattt caaagcagac
    25801 tggtcgcctg atacattgat gggaaataat tatatctctc acttaggcgt atatcgaaca
    25861 agcattgtta aagaacttgg cggtttccgt aaaggctatg aaggttctca agattatgat
    25921 ttggtccttc gtgtgacaga acaaatccct gcagatcata tttaccacat tgaccgagtc
    25981 ttgtatcatt ggcggacgat cccaggatca actgcaagta atggcgaagc caaaagttat
    26041 atctatgatt ccggagtgaa agcattgaca gatgccctgt ctagaagaaa catcaaagga
    26101 agcgtacgtc ctggcagaat ttctggattt tatgagattg cttatgacgt cttgcaagag
    26161 gatttggtca gtgtgatcat tccaacgaag aatggctatg aagatctaaa aacttgtgtg
    26221 gattcgatca tcgaaaaaac gtcttattca aattatgaaa tcattattgc ggataacgga
    26281 agtacagatc caaaaatgca agaattattt gcagaataca agcatcagct gaaagaccgc
    26341 tttatcgtag aattgattga cattccattc aattattctc gaattaacaa tttagcagca
    26401 gaaaaagcaa acggcaaata ctttttattc ttgaataacg atacagaagt gattgagcca
    26461 gattggatga cggtgatggt ttcttatgca cagtttgatc gaatcggctg tgtaggagca
    26521 aaactgtttt atccagatga tacaacgcag catgcaggag tattattagg aatcggtggt
    26581 gttgcagggc atgcattgaa taactatgat cgaacacatt gtggttattt cggccgattg
    26641 gtcattgacg tcaattactt agcagtcact gcagcttgta tgatggtcaa ggcagctgac
    26701 ttcaatgctg ttaacgggtt tgatgaaaca ttagaagtag cattcaacga tgttgacttg
    26761 tgcttgaaag tttatgaact gggtcgttac aatgtctatg cacatcaagc agaattgtac
    26821 catttcgaat ctaaatcaag aggttatgaa gatactccag aaaaacaaag acgttttgct
    26881 ggtgaaatca aaaaaatgca agataaatgg ccagcatata ttgcgcatga tccattttac
    26941 aatgataatt taacaaaaga aggaatcggc gacttttcgt tgagaccaga ttaaactata
    27001 ataaaaagct gttatgttgt gattcgctcg cacataacgg ctttttatag ttttttgtca
    27061 aaaaaaggca gaaggtgccg actcaaaaaa ataagtcgag gttgggacag aagtgtttaa
    27121 ctccgagaaa taagaagaaa ttcacgaaaa ttgcttttca aatttttgtg aatttcggct
    27181 tatttaagaa gaagttgctt ctgctcccac cgtttattcg tttttaaaga atgagacaaa
    27241 agtgtttctt acttttgtcc cacgctctta ttcatgctca gagcgccaat agatacaaaa
    27301 tcatagccaa agtttcacga accctagctg tcaaagaatc gatattttat tttaatatag
    27361 gctattttaa aataaatggt ttaaggtatt cctctacaaa agccactcta tcaattatca
    27421 tgggtttaaa ataagaagtg atggagataa ccagattgtt cttagcgtca atataaagaa
    27481 catttccact attaccaatt gctgaatata tttcgttctc agaatctaat acccaccata
    27541 aatagccata tctcatattt tgtaagtctt ctaaagcact ggttctaggt ttgaacatct
    27601 cgtttatcca catgggtggt acgatttgtt ttcctttata catcccttta tttaggcata
    27661 atacaccaat ttttgccaga tcacttgccg ataaacacaa accatatcct gccgtcccga
    27721 tatttagtgg atcacaaaac cagacattgg ttttaggaga cttatccatt gtaaactgct
    27781 tatgttcttc agctgtttca gcataataat tgacatggtt tggtatccct ataggatcaa
    27841 atagatactt attggcaaaa tcaacagttg ttagcttact tgtctgatac aacaagccag
    27901 ttaatatgtg taaacagaca gtttgatagt tgaattcgcc ggttatacct tttcttcctc
    27961 ccaataaatc tagtgatgtt tttgtccaat cttcacttga acagactttt gtccatggat
    28021 cgcctttaca tttgtagggt gctttcattg ttagcaagtg cttgattgta atagcgtaaa
    28081 tagttttctc cccgcgtttc actttatact ctggaaaata atctaatact ttatcatcga
    28141 tacttttgat taatccttgc tctaaagcaa tgccaatcag caaagataca atacttttcg
    28201 ttgctgacat gatatgacaa gtatcgtctt ttttataacc attccattca tctgtataaa
    28261 cttctacccc atccttatat gcgacaattt gacatatatt tggttgtcga aaaccaataa
    28321 aatcatgcaa ctcttgttta ttcataagat attacctcac tttcttctat aagcataatg
    28381 tcattaaaaa tcgatttcaa ttttttcgat tcttcacgta atacaggtat tcttatggac
    28441 tagacagcgc tttgggaaga tggattctct gaaaaatata aaggttcact ttatgagtgg
    28501 ataaaaaaag cagcaaatac ttcgacttct ttaatttacc aacattagtg aaaatcgatt
    28561 catctggaga tttgtaattt agagtccttg tcttgattag aggtgtataa agctttttat
    28621 tagacatttt taaattccat tacaatttgc ttataaacta ggtttttaaa ggtgactatg
    28681 gtaagataat agagatatta ttttgtgatt aggagtgtat atatgaataa aaatggagaa
    28741 tggagtgctg cacgacggat attcattata ttaatggatg ttattgtata caatgcagca
    28801 atatatagta gtttcttact gaagtttcgt ggagagatcc cattacgaaa tttagaaact
    28861 ttccaacact cagcaattat tatttcagtg atttttattg cgttgaacat tttgttgggt
    28921 gcatatgttt tttataatcg aatgatcagt gacatcgtgt ttgtcacagt catcggtcag
    28981 gtattgatga cactagggat catggtagtg acttttgcgg gccgctggtt tgcttttcca
    29041 cgtcttgtta tcttactttc atttgttctc ggtacgcttt tcttaagtat ctatcgtatt
    29101 ctcgtatata aactttattt acgcgtaagt cgagataaaa aggtcgtcat tattgggtta
    29161 gaaaaggatg tcgcaccagc aatccaaaat tttggttcaa agaaaaacaa caaacataaa
    29221 gtcgaagcag tcattcttga taactattat gcaaacatca aaaatatgat taaagacatc
    29281 gatattgtct atcttgcttc tcatatcgaa gaaactgaaa aaatcaaaat ctatcaatta
    29341 gttactaaaa atgaaaaaaa attgtttttg aatacaacat ttgaaaactt gacattgatc
    29401 aatccaaata ttatgaattt cgaagatgaa agtattattg aagcatctgg atttagaatc
    29461 caacctgaat atgaactatt caaacgtttg tttgatatca tcgtttcact tgttttatta
    29521 gttattgctt caccatttat gttattcaca gcaattttag tcaaagtgac atcaccggga
    29581 ccaatcatct ataaacaagt gcggatcaca aaaaatcaaa aggaattttc aatctataaa
    29641 ttccgctcga tgaccgccac agccgaagca aaatctggac cagttttagc taagagcaat
    29701 gatgcacgag taacgcctgt aggtaaattt attcgagctg tccgctttga tgaattacca
    29761 caaatcttca atgtgctgaa aggcgatatg tcgatcgtag gaccacgtcc tgaacgtcct
    29821 ttcttcgtcg atcagttcaa tgcagaaaac ccttattact acttacggca taatgttcgt
    29881 gctggtatca ctgggtatgc acaagtctat ggaaaatatg tctctgatta caacagtaaa
    29941 ttacgttttg atttacttta tatcaaaaaa tattcattga tgcttgattt aaagatcttg
    30001 ctgcaaacca tcaagatcct atttgataaa atgtcctctc aaggacttga agaagacgaa
    30061 aatgtgatct cattggcaga aattgctttt ccgaatgaaa aaatctttcg ctagttggga
    30121 ggcgtaaaaa tgaacaatcc gaaattcagc ataatcgtac cagtatacaa tgcagaagca
    30181 actattggtc gaacgattga tattctaaaa gaattggatt atgaagagta cgaagtcgtt
    30241 ttagtaaatg atggatcaac agatcaaaca caggaaatca ttcaagaact gattgaaaat
    30301 gatgaacgtt ttgaattgat tactacgacc aatcaagggc ccggattagc aagaaacgaa
    30361 ggaataagac agtcaaaagg agaatatctc ttattcttcg atgcagatga cacgccagta
    30421 aaaacgatct tgtcagatta tgatcatttg ctagaaaaga gtccaaaagc ggatcttgtt
    30481 gttagttcgt ttgtttttcg tacaatggac gagggaagaa tcgtttccga aaaagaaaac
    30541 ttagttacag aatgtcacta tctaactcac gaagagttta taaaagacat gtatcagtta
    30601 atgaatgaac agttgatgta tgttgtatgg aacaaatgct atcgtagcga tattctgaaa
    30661 aataaccaaa ttctatttaa aacttataat agttgtgagg atcgaatatt taacttacat
    30721 tattatgaat actgtcatca agtgatcatg aacccaaaag tagaatatat ttatgaattt
    30781 gaaggtggga aggggatcac taatcaatac cgacctaaca agttcgaaac atttaaagaa
    30841 ttctattcat tagcaaatac tgtaacagac gatattaata aagacggtat ggcggcgctt
    30901 cttttaaaag ggacaacttc agttattttt tctatttata gtacctctgc aagaacttca
    30961 aaagagaaga aagacgaagc aaagcagata ttgagtgatc cagtgatccg agaagccaag
    31021 caaattgcta agacggattc ttcagcaaaa aaaataacaa agttgcttta caatatgcca
    31081 gctccactat ttttatctgc tgtaaaagtt ggaagcttcg ttgaagtgaa aatgccaggg
    31141 ttaatggctg ctttgaagcg agtatattag ttaatggagg aaaatataat gaaaagaatt
    31201 ttgcattttc agggacgaat gggtttaggt ggagcagagt ctttcatgat gaatttatat
    31261 cgtaaaattg atcgtacaaa ctatcaattt gattttttga tttatgaaga ttatgcagat
    31321 gttcaagact atcattcaga gattgaaaga ttaggaggcc gtatttttgt tgtacctaat
    31381 cctaagaaaa atatttttaa atatttaata gaagtgaata agttactaaa aaaagaatct
    31441 ttttctatag ttcacaatca ggtttatttt ggcgggggaa ttaatttatg gttagccaaa
    31501 aagaatggaa tcagacagag aattgctcat agccatgcaa ctgaagatgg aaaatctcaa
    31561 aatattgtaa tgaatgtatt gcgtaaattt ttaaccaaat tgttgttaca aaatgcaaca
    31621 gactaccttg ccgttagtca agaagctggt gaaagtctgt ttcaaaacca cccctttgag
    31681 atagttcata atggtattga tttagagctt tatagtaaaa attcagaagc taaggttaat
    31741 aagagaaaag aattggatat ctcaatgagt acttttgttg tgggaaacat tggacgatta
    31801 gagaaacaaa aaaatcaatc ttatttgtta gagatttttt tagaaatact aaaaatgaat
    31861 tctgattctt acttgatttt agtaggtgaa gggtcactta gaaataaact gaaagccaaa
    31921 gcagtagaat tggatataga gaaaagagta aaatttttag gagaaagaaa cgatattccc
    31981 gagttattat ctgtgatgga tgtttttgta atgccttctc tttatgaagg tctgccaatg
    32041 gttggattag aagcacaagc agcaaaatta aaattagtct tagcagatac tatttccaaa
    32101 gatacaaagt taacaaataa tgtggatttt gtatcattag atgaaacacc acaagaatgg
    32161 gcaaaaaaag taataaaaga gccgtatgct aataaaataa cacaagaact aaagagttat
    32221 gatgtttcgt acactactga acaaatggag agtatatata gtagagatca ttaaaaatgt
    32281 tcaagatatt ttaggagtga ttatttttga aaatatgtta tttgatattg gcatacaatg
    32341 atattggcaa cttaaagaga ttggtcaatc gattgaacga aaatgcagtt tttattattc
    32401 atatagataa aaaaactgat atagaaccat ttattgaagc atttaaatca tatgataatg
    32461 ttgaattttt atgtaataaa aaccgtgtta aaatttattg gggtggtttt tccattgtac
    32521 aagcagaaat caatttagta aagagagcat tacaaaatga gaaatattta aaatatgtat
    32581 tattatctgg tgctgattat ccaat
//
LOCUS       DAFLWC010000024        32280 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.024, whole genome shotgun sequence.
ACCESSION   DAFLWC010000024 DAFLWC010000000
VERSION     DAFLWC010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32280
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.024"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(75..1016)
                     /gene="ribF"
                     /locus_tag="L1V17_001041"
     CDS             complement(75..1016)
                     /gene="ribF"
                     /locus_tag="L1V17_001041"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HBN1235825.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            complement(1020..1943)
                     /gene="truB"
                     /locus_tag="L1V17_001042"
     CDS             complement(1020..1943)
                     /gene="truB"
                     /locus_tag="L1V17_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBN1235826.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            complement(2311..4673)
                     /locus_tag="L1V17_001043"
                     /pseudo
     CDS             complement(2311..4673)
                     /locus_tag="L1V17_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            5121..5294
                     /locus_tag="L1V17_001044"
     CDS             5121..5294
                     /locus_tag="L1V17_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1235827.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            complement(5451..5798)
                     /gene="rbfA"
                     /locus_tag="L1V17_001045"
     CDS             complement(5451..5798)
                     /gene="rbfA"
                     /locus_tag="L1V17_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBN1235828.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(5825..8131)
                     /gene="infB"
                     /locus_tag="L1V17_001046"
     CDS             complement(5825..8131)
                     /gene="infB"
                     /locus_tag="L1V17_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBN1235829.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(8144..8455)
                     /locus_tag="L1V17_001047"
     CDS             complement(8144..8455)
                     /locus_tag="L1V17_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HBN1235830.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(8452..8745)
                     /locus_tag="L1V17_001048"
     CDS             complement(8452..8745)
                     /locus_tag="L1V17_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBN1235831.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(8767..9942)
                     /gene="nusA"
                     /locus_tag="L1V17_001049"
     CDS             complement(8767..9942)
                     /gene="nusA"
                     /locus_tag="L1V17_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBN1235832.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(9965..10438)
                     /gene="rimP"
                     /locus_tag="L1V17_001050"
     CDS             complement(9965..10438)
                     /gene="rimP"
                     /locus_tag="L1V17_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBN1235833.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(10583..14941)
                     /locus_tag="L1V17_001051"
     CDS             complement(10583..14941)
                     /locus_tag="L1V17_001051"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBN1235834.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            complement(15153..16862)
                     /locus_tag="L1V17_001052"
     CDS             complement(15153..16862)
                     /locus_tag="L1V17_001052"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBN1235835.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            complement(16930..18198)
                     /gene="rseP"
                     /locus_tag="L1V17_001053"
     CDS             complement(16930..18198)
                     /gene="rseP"
                     /locus_tag="L1V17_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBN1235836.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(18359..19159)
                     /locus_tag="L1V17_001054"
     CDS             complement(18359..19159)
                     /locus_tag="L1V17_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBN1235837.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(19156..19968)
                     /locus_tag="L1V17_001055"
     CDS             complement(19156..19968)
                     /locus_tag="L1V17_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBN1235838.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(20163..20720)
                     /gene="frr"
                     /locus_tag="L1V17_001056"
     CDS             complement(20163..20720)
                     /gene="frr"
                     /locus_tag="L1V17_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBN1235839.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(20723..21445)
                     /locus_tag="L1V17_001057"
     CDS             complement(20723..21445)
                     /locus_tag="L1V17_001057"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBN1235840.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(21581..22462)
                     /locus_tag="L1V17_001058"
     CDS             complement(21581..22462)
                     /locus_tag="L1V17_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBN1235841.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(22561..23343)
                     /gene="rpsB"
                     /locus_tag="L1V17_001059"
     CDS             complement(22561..23343)
                     /gene="rpsB"
                     /locus_tag="L1V17_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBN1235842.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            23702..24181
                     /locus_tag="L1V17_001060"
     CDS             23702..24181
                     /locus_tag="L1V17_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HBN1235843.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            24398..25489
                     /gene="phnW"
                     /locus_tag="L1V17_001061"
     CDS             24398..25489
                     /gene="phnW"
                     /locus_tag="L1V17_001061"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HBN1235844.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            25482..25610
                     /locus_tag="L1V17_001062"
     CDS             25482..25610
                     /locus_tag="L1V17_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBN1235845.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            25614..26159
                     /locus_tag="L1V17_001063"
     CDS             25614..26159
                     /locus_tag="L1V17_001063"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBN1235846.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(26613..28304)
                     /locus_tag="L1V17_001064"
     CDS             complement(26613..28304)
                     /locus_tag="L1V17_001064"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBN1235847.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(28724..29671)
                     /gene="arcC"
                     /locus_tag="L1V17_001065"
     CDS             complement(28724..29671)
                     /gene="arcC"
                     /locus_tag="L1V17_001065"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HBN1235848.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(29786..30805)
                     /gene="argF"
                     /locus_tag="L1V17_001066"
     CDS             complement(29786..30805)
                     /gene="argF"
                     /locus_tag="L1V17_001066"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBN1235849.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(30896..32125)
                     /gene="arcA"
                     /locus_tag="L1V17_001067"
     CDS             complement(30896..32125)
                     /gene="arcA"
                     /locus_tag="L1V17_001067"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HBN1235850.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT         8602 a         6928 c         5728 g        11022 t
ORIGIN      
        1 tcctgggctt atttatcacc cattttattg taattgctag ttatacataa acaagagatt
       61 ttatgcataa tgttttattg ctgagaaaaa tattcagctg ttgcttgttc atcctccttg
      121 agttgttcaa tcaattcctc tacactagaa aatttcactt gatctcttaa aaattgattc
      181 cagcgtaccg cgacatgttc accatagata tcttgattaa agtccaaaat atacaactct
      241 acagtcagct cccgtccttc accgaatgta tcattatgtc caattgaacc catggctgga
      301 taccatgttt ccccaatttt tatttccgac acataaacac cttctttagg caaatgaacc
      361 gtgctcttta ctttgacatt tgctgtaggg aatcctagta gtctgcctcg tgcatcgcca
      421 tggacaacta ccccttctac ctcatatgtg caacctaata gttttgctgc ttcttttact
      481 tgtccgctgt ctagtaatcc acgaatacgg gtagagctga ttttttcacc ttgttcttct
      541 tctttagaaa ctgtgacgat tttgaatctt cctttggcat attcaggaaa atgagcgaca
      601 tctgcaatgt cttttggtcc atacgtataa tcaaaaccgg aaacagcata ttttgcatgt
      661 aaccctacga tgtattgatc aacaaattcc tgcggtgcta aatgagcaaa agaagaagta
      721 aaatcaactt catataaata atctataccc aaagcggcca ttttttcttc tttttgctta
      781 aggctagtca aatatttcac gctgctagga tcgatctttt taaagacaat agatggatgc
      841 tgattgaaag tcatcaatgc taatttcaat ccttcttttt gtgcaatttc catacctgtc
      901 tttatgactt tctggtgtcc gatatgcacg ccgtcgaaaa atcccagcac taaaacgaca
      961 tcgtcttctg gaatttgttc tgattggtaa ggatgtctga tcttgatgat attcattcgt
     1021 tattcctcat ttctcaatac tttactaggt tttaatttgt ttttttcttt cgggtttggc
     1081 tgataaatac tgacaacttt tcctttataa aacaaagcaa tttcttctga cggcatttct
     1141 gggagcgcaa atacagtata atcaagtctc ataccgtttt ttactttctg ccatacttca
     1201 tcagtaatat ctactcgttt gaaccgttcc actccttttt ctattggcag caaacaatca
     1261 tcgattgtcc catttttcac agcttgagct acttcttcta atgtcagagc atccttctgg
     1321 gacataccgg cacttgctgt tcgggtcaga tcagacatgt gcgcagggta accaagtttc
     1381 ttgcctgtat ctacagctaa tgtgcggaca taggttcctt tcccgcattc tacttcgaag
     1441 cgccaagaaa tggttcctgt cacttcgtct cttgtcaatt cacttgtccg gataaaacgg
     1501 taaatctgag cctttctaac aggacgctcc actgtttcat tattgcgggc atattcatat
     1561 aaccgcttac cgttgacttt taccgctgag tacattggtg gtatctgggt gatctcacca
     1621 ataaatgaag ccatcacttc atctattttt ttttcagata aagacatatc tactggtttt
     1681 gtttctaccc gttctccgga tcgatcttcc gtcgttgtac tgaaacctag agttatctcg
     1741 cctacataga ttttcccaga atctgtcaaa tattcgataa cttttgtggc ttttccaata
     1801 caaatgggca acacaccgtc tacgtctggg tcaagcgtac ccccatgtcc gatttttttc
     1861 gtatgtaaga tttttcttaa tttgaatacg caatcatgac ttgtcattcc gcgttctttc
     1921 cataaaggta ataacccgtc catgtctttt ctccatttca tttttgattt aactgaatta
     1981 ttataacaca ttgcatcaat tactgacgaa tttgacatca taatgaacgg tttttatttt
     2041 tcggcaataa aaacgtaaca aaattcatgc tcacgtaaat agaaatcatg ttatgctttt
     2101 ttaaaggagg gaatagaatg gaagattttt tctttgcacc atttgattgg atttatgggt
     2161 ggcttacagg taaatagttt ggttttcact tcccaaaaac gaaaaaaaag actggccatt
     2221 cttccagtct tttttccgtt ttttttattt attttttcag tttcttaatc aatgtaaaaa
     2281 attctatttt gcgggatcga ttttatcatt ttattggtca agatttttcc atttccaatc
     2341 caatacttct ggcagatcaa taccattttc acgaatatag ttttgatgtt cttgtaattt
     2401 ctgatccatt tttttcgcaa aatcttctgc ttgacttcct ttgattttta aagctgcgtc
     2461 ttttgccaaa tgataacgat caagttcatt tactacacgc atgtcaaatg gtgtcgtgat
     2521 atctccattt tctttgtagc catgaatcat taaatgatgg ttatgacgat caaagaaaat
     2581 cgtgcggacc aatgtttcat aaccgtggaa agcaaataag atcggtttgt cttttgtaaa
     2641 atattgatca aattcttcat cgctcaaccc acgcggatct tgacttggat gacgtaattt
     2701 caataaatct acgacattga tgaaccgaat ttttagtttt gggaattctt ccagcagcaa
     2761 agttacagct gctaatgctt ctaagttaga ttccgttcct gcagcagcaa tgaccaattc
     2821 aggttcctcc tcttttgctg tcgaagccca atcaatgatt ttcaagcctt cattcactaa
     2881 gacggctgct tcttctgctg agtaaaattg agcacgcgga tgtttggaag agatgatcaa
     2941 attgattttt tctgacgagc ggaatgcttt atccatgact gcgagcaatg tatttgcatc
     3001 cgcaggcaga tattcacgga tgaactccgc cttcttttct gccaaatgtg tcaatattcc
     3061 tggatcttgg tggctatatc cattgtgatc ttgctggaag actgttgagc ttgcaatgag
     3121 atttagcgaa ggataatcat ttcgccaaga aaggtcatgt gatttccgca tccatttgaa
     3181 gtgctgagtc aacatagagt caaccactcg caagaatgat tcgtaacttg caaaaaacca
     3241 tgccgtccag tcagaacgta cccttctaag aacccttcat cttggtgttc cgataattga
     3301 ctgtcgatga cgcgaccaga tggcgaaagc cattcatcat tttctggttc gattttttcc
     3361 atccattggc gatttgtcgt tttgaaaact tgattcaatc ggtttgattt tgtttcatct
     3421 ggtccaaata tacggaaatt ttctggattt ttctcaatga tctcgcgaac gaatttacca
     3481 agttcggtca tatcttctgc tttaacggag cctggttttt caaattgcaa agtatatttt
     3541 ttccaatctg gcataataag cggtcttgga tcgattccac cattggtgat aggatttttt
     3601 gccattcttt ggtcaccagt aggcgcgatt tctctgattt cttctaaaat acgtccttgt
     3661 gcatcaaata atttttctgg ttcataggat ttcagccaac ggagtaaagc atctgcatga
     3721 tccatatgtt cttgatctac aggaatcggt acttggtgtg ctcggaaggt tccttcaatt
     3781 ggttccccgt cccattcttt tggaccggtc catccttttg gtgtgcgtac gatcaatact
     3841 ggccattttg gcatcacgac atctgttgct gtcttcaggc gagcttcttt ttggatggat
     3901 ttaattttct cgattgcttg atccattttt tcagccataa caggatttaa tttttctgaa
     3961 tcatttcctt caataaagaa aggttcccag ccaagtccgt taaagtaatt tgctaattct
     4021 ccatctgatt tacgtgccaa gatcgttggg ttggctattt ttgcaccatt taaatgaagg
     4081 atcggtaaaa cagctccatc tatcactgga ttgataaaga catttgagaa ccagcttcca
     4141 gctaaaggac cggtttctgc ttcaccatca ccaatcacga cagcagagat tacttcagga
     4201 ttgtctaata cagctccgac tgcatgtgaa agagagtatc caagctctcc gccttcatgg
     4261 atagaacctg gtgtttctgg tgctgcatga gaagcaatgc ctccaggaaa tgaaaatcgt
     4321 ttgaataatt tttgcattcc tgtctcatct tccgttactt ctggatagat ctctgtgtaa
     4381 cttccatcta aataagcatt cgataccatg acttgtccgc cgtgtcctgg cccttcaata
     4441 taaaacatgt tcaaatcata tttattgatg actcggttca aatggacata aataaaattt
     4501 tggccaggaa tcgttcccca atgaccgatt ggatgttttt tgacatcttc gggtttcagt
     4561 gtacgtctca gtaaggggtt atctttaaga taaagttgcc caacagaaag ataattagca
     4621 gcacgccacc aagccgtcat tttatcaaag tattctttac tagaataatc catacataac
     4681 actccttttc attattactc ttattctagc gcagatactc ccaattgaaa cctaataagc
     4741 acttctgttc atttgtttgg attttatatc tagccaaatg aacaggtata aaaaaccacg
     4801 aaatttttcc tttcgctgac gttttttaca ttgatccaaa aaacttgtcg ttatcacaat
     4861 ggctgttccg cagttcattt cgctcctcat catgcataat ttgctgaatg acgctgggcc
     4921 agttaacaca ttgctggaaa actggggctg gatcgagcaa ttcctttcct gattgatccg
     4981 ttttatgtaa aagtctctgt tatctttgtc aatatgtgaa ttggtatccc agctactatg
     5041 ctaatttcta cagggattat ccaaaatttg gatcgtgacc aaatcgaagc ggcgtaatcg
     5101 gaaatatcaa taacttcaac gtgatttttc ttttaactgt caacggaccg acaaactcaa
     5161 acttttatgg tgcaggttcc actgatcttc tagttacttg gctatacctg actgtcacta
     5221 aaatagatta caatctagct tccgttatcg gtatcttgat ctttatctat atgcaaaaat
     5281 ttatatacta ctagaaaaaa gaaagtcgaa ttttttactt ttctttttct cttttttggt
     5341 tagctgacac gccgcaagac taaagtcatg gaactcttag gtaatacgtc ttaatgaaaa
     5401 caaaaaaatc ccgcaacccc tgatttcaca ggatttgcgg gagtttttga ttagtctttg
     5461 ttcaagtcgc gaagcaattc atcgatatgg ttgccataga caactgattc atcaagttca
     5521 aagaacaatt caggtgtctt ataaatactt agattgtgcc ctaactctcg acgaatcaat
     5581 cctgatgctt tattcaatcc atcttgtgct gttttcttat ctgatgctaa gtcagataaa
     5641 atgctgtaat agatcgttgc ttgctgtaag tcccccgtaa ctttcacatc tgtgatcgtt
     5701 acgttctcca cacgagggtc acggaccttt ttgcgcaaaa tatcattgac ttcttttaag
     5761 atttcttgac cgactcggcg gtcacggtag ttagccataa tgattggcct ccttttatca
     5821 gtttttagtc atttttgact tcttccatga taaatccttc aattacgtca tctactttga
     5881 tgtcattgaa tttttcaatc attgcaccac attcataacc cattttgact tctttcacgt
     5941 catctttgaa tcgtttcaga cttgcaagtt ggccttcata gattacgatt ccgtcacgga
     6001 ttacacggac accgctatct ctacgaatat atccttctgt tacataggca cctgcaatcg
     6061 taccaacttt agaaactttg aaggtttcac gaacgatcat ttgaccggtg attttttctt
     6121 caaattcagg gtctagcatc cctttcatcg cagtttcgat ttcttcgatg gctttataga
     6181 tgatacggtg aagacgaata tcgacttctt cagtatcagc ttgcactttt gcctgcggtg
     6241 taggacgaac gttgaaaccg atgataatag cgttgctggc tgctgctaag gttacatcac
     6301 tttcattgat tgctccgaca gctgaatgga cgatttttac acggacacct tccacatcaa
     6361 tcttcttcaa tgatgcagcc agtgcttctg ctgaaccttg tacatctgct ttgatgatta
     6421 cgttaacttc tttcaattcg ccttctttca ggctttcaaa taagttatcc aaagtcacac
     6481 ggcttgtggc agcacggttt tctaataatg cacgtttcgc gcgttcttca cccgctgcac
     6541 gtgctgtctt ttcgtcttcg aagactacga aacggtcacc tgcttgaggt acatcattca
     6601 agccagtgat ttctactggc gttgcaggtc ctgcttcttt atcgcgacgg ccaagatcgt
     6661 ttgtcattac acggacacgt ccgtaagtat taccgacaac gattgggtca ccaacatgaa
     6721 gtgttccttc ttggacaagt aaggttgaca caggaccttt acctttatca agacgtgctt
     6781 cgatcactgt tccgattgcg cgttgtgttg gatctgcttt taaatcttct acttctgcga
     6841 ctaacaggat catttccagc aattcttcga tgttttggcc gaatttcgct gagatctcaa
     6901 caaagatcgt ttctccaccc catgcttcag gaattaactc atactcactt aattcttgca
     6961 taacatgttg agggtttgca cctggtttat caattttatt tacagcgacg atgattggaa
     7021 cgcctgcagc tttggcatgg ttgattgctt caactgtttg tggcatgacg ccatcatctg
     7081 cagcaacaac taagatcgtg atatctgtga tacttgctcc acgtgcacgc atacttgtaa
     7141 aggccgcatg tcctggtgta tccaagaaag tgattggttt accatcaata tcgatctggt
     7201 aggcaccgat atgctgtgtg attccgccgg cttcgccgct tgttacacgt gaatggcgta
     7261 atgtatccaa taaagttgtt ttcccatggt ctacgtgtcc cataatcgtt acgactggcg
     7321 gacgtgagac taatttatct ggatcgactt cttctgcctc gaagaattta tcgatatcag
     7381 caatgtcaac ttggactttt tcttgtggtt ccatgccata gtccgtcgct aacagttcaa
     7441 tcgtatcttt atccagtgct tggttttgat tgaccatgac accaagcata aataattttt
     7501 taatgatttc tgctggctca cgatgaattt ttttcgcaat atctgctacg ttcatacctt
     7561 cagtatactc taatacatct ggcaattcac ggaatttgcg tggtggtaca gctggtttag
     7621 ttgattgttg ctgtttgcct tttttacctt ttttattata acgattacgg ttattattat
     7681 taaatttgcc gcgattgtta ttgtttggtt tgttgttatt gttagtacgg ttttgattgc
     7741 cgccttggct cgttccttga cgattttggc tgctggtatt tcccgtatta ttttggtttg
     7801 ttgttggttt ttttccttga ttcacttgac cgctcccttg accgcgatct tgataactgc
     7861 ggttattttt atttttttgt tgattgttcg ttgtttcttt tttacgttga tcgttcggct
     7921 gttgattggc tggttttctg cttgcttgtt gtgcagcttg ttgtttcgtg cttgggtttt
     7981 tgaacgcttg ttgcaatttc ttctcatcat tgctagtaat cgcacccata tggtttttca
     8041 catcgatgcc aagttgttgt gctttttcca cgacgtcttt actagatttt ttgagttctt
     8101 ttgctaattc atagattctt ttgttgccca tgcaatcacc ttcctaacct tcaattagct
     8161 ccttggtctt cttcgcaaat ccggcatcca ttattccgaa taccttgcga ggttttccga
     8221 tcatctgcgt gatttctgct tcagaaaata gctcaaagca aggaacttca taatatgaac
     8281 tcttatcttt tatctttttt cttgtattct cgcttgcatc ggttgccaca aacaccaatt
     8341 ttgctttttg tttgcggatt tcagcaatgg tcagttcttc acccgtgatt agttttcccg
     8401 cgcgcatcgc tagaccgatg agattcatgg ctttttgccg attaactgta ttcattttcc
     8461 aaataactct ttacgtgctt tttggtgagt gacatagtca agaagttctt gataaaactc
     8521 atctgttaat gttgtttcga gtactcgatc gagaattttt ttatcccaag cttgttgtac
     8581 ttcttccggc tcaagtgaga catacgctcc tcgtccaggc atttttccag ttggatcgat
     8641 cgatacttcc ccttcttttg aacgggtgat tcggaccatc tcttttttag gtttcatttc
     8701 acctgaaacc acggatttgc gtaaaggaat tttcctttgt ttcatctctt tgcctcctta
     8761 ctaaagttaa gcttctggtt tttcttcgac cgtttcattg ttgaatgcaa ttgtttcata
     8821 ttcatcgtct gttaaatctg actgaacgat tgcttcatca tgcagttctt ctgtttcttt
     8881 ttgttgttct tgattttcat aaaattccgt catgtcagat tctgatttga tatcgatttt
     8941 atggttagtc aatttagcag ctaaacgtgc gttttgtccg cgtttaccga ttgctagcga
     9001 taattggtag tctggaacga caactgtgca ggcctttgga tttgtctcat cgaagatcac
     9061 atccatgact tgtgcaggat tcaatgcatt tgcaatgaat acagctggat cttcattcca
     9121 ttcgacgata tccatgtttt cgccttttaa ttcattgacg attgcttgaa ctcgttgtcc
     9181 ctttggcccg acacatgtac cgactgcatc gatatttgga tcatttgagc gaactgccac
     9241 ttttgaacga tcgccagctt cacgggcgat gctgacaatt tcaacgattc catcatagac
     9301 ttctggtact tcttgctcaa ataagcggcg caataggtct ggatggctgc ggctaacaaa
     9361 tacttgcgga cctttagacg tattttctac tcgggaaaca taaactttga ttcgatcatg
     9421 tggttgataa aattcatttg gcatttgatc ttgtttagaa agaactgcct caattttacc
     9481 aagattgaca taaatataac gtttatcctg gcgttcgacg attccttgca tgatgtcttt
     9541 ttcataagca ctgaattcgt tataaataat cgttctttct gcttcacgta cacgctgtaa
     9601 aataacttgt ttagccgttt gcgcagcgat ccgcccaaaa tcttttggtg ttacttcaaa
     9661 acggatcgta tcaccgatct catatgctgg attgattaaa agtgcatctt tcaatgagac
     9721 ttccaactgt gaatccatca cttcttccgt tacttctttt accgcataga catggatctt
     9781 tccttttttc tgatcaaatt ccacttcgac gttttgtgct tggccatagt gacgtttgta
     9841 tgcagaaacc aatgctgctt ctaaagcatc gatcacgatt tcttttgaga tccctttttc
     9901 agcttctaaa gcgtctaacg catttaacat ttctttactc attttttctg attcctctcc
     9961 gtgattaaaa ttggatagct aagcgagctt ttgcaatatt ttttcggtca aaagtcaatt
    10021 ctttttctcg tgtttttatg cgtattttca atgtaagctg ttcagcatca aatgattgaa
    10081 gaaatccttc atattgtttt tcgccatcta ctggttggta taaggagaca tggacataat
    10141 caccaagtgc cttttcatag tcgctttctt ttttcaatgg ccgctctgct cccggggagg
    10201 atacctccag gaaataagct tgaggaatcg gatctggatc tgctgcatca agtttttcac
    10261 tcagtttctc actgacaaag gcgcattctt cgatatcgat accgccttct ttgtcaataa
    10321 atactcgtaa gaaccagctt tttccttctt ttacaaattc gacttcgaca agttcaaaat
    10381 tttgttcatc taaaatcggt gtcaccattt ctgtgactgt ttcaacgacg ctactcaaaa
    10441 gtttcgcctc cttaaaaaat taagtgcgta attccattaa aaagagtgag cgaaaaatcc
    10501 gctcactcac agttagtatc attacctata agaactatac catactctgc ttaaaattac
    10561 aagcagacag gaaaacagat gcttatagca tatcgaataa cgataattga ttttcatctg
    10621 gtagatcttt caatacgcca ttgtcgttca tatattcgat caatgttttt gaaactttac
    10681 cgcgggtggc aagatcttct ttggataaaa atggaccgtc ttttcttgct tcaacgattt
    10741 gttttgccac gttggttccc aaacttggga cagctctaaa tggtgcgatc aacgtatcac
    10801 cttcaataac aaagttaacg gcatccgatt tatacaaatc aatcattcca aatttgaatc
    10861 ctcgttccag catttcattg gctaactcca gcactgtcag ttgattcttt tcttttacgg
    10921 aagcatctaa tcctttgtcc gtgatttctt tcattgcttg tttcacagca tcttttcctt
    10981 tgcacatgga gactagatca aagtcgtctg cacgtacaga aaagtatgca cagtaataca
    11041 aaatagggaa ataaaccttg aaataagcga cacgaagagc catcaatacg taagctgcag
    11101 catgggcttt cggaaacata tatttgattt ttgaacaaga atcgatatac cagtcgggca
    11161 cattattttc tttcatcgcc gatagatagg tttctcgcaa ttcatcaggg atcttgttcc
    11221 attgtccttt acgaacagtt tccatgattt taaatgccat cccgctatct aatccagcat
    11281 ggatcaaata aaccataata tcatcacgac agccgattac ttccgccagt gtcgcatctc
    11341 ctcgtcgaat caattcttcc gcatttccta accatacgtc tgtaccatga gatagtccgg
    11401 aaatttgcag tagttctgca aaagttgtag gatgcgtttc ttctagcatc cctcgaacaa
    11461 aacgagtgcc gaattctgga atacctaatg tccctgtttt ggaataaatt tgttcctgac
    11521 ttactccaag tacttcagga ccggcaaata tccgcatcac ttccgggtca tccgtaggga
    11581 tcgtttgtgg atcgatccct gataaatctt gaagcatccg aataacagtt gggtcatcat
    11641 gccctagaat atctaatttc aatacattat cgtgaatcga gtgaaaatca aaatgagtcg
    11701 ttttccattc cgaattttga tcgtctgctg gatattggat cggcgtaaaa tcatagacat
    11761 ccatataatc gggaataacg atgatccccc ctggatgctg gccggttgtc cgtttgactc
    11821 cagtagcgcc ttttgctaat ctgtcgactt ctgcacttcg aaactgcaga ttattgtccc
    11881 tttcgtatcc ttttacatag ccatatgctg ttttgtcggc gactgtacca atcgttccgg
    11941 cacggtaaac atagtcttcg ccaaacaata ctttcgtata gttatgggct tctgcttgat
    12001 aatcacctga gaagttcaaa tcaatatcgg gcactttgtc tccatggaat cctaaaaatg
    12061 tctcaaatgg aatatcatga ccgtctttgt ttaagcgtgc accacatttt ggacattgtt
    12121 tttctggcat gtcaaatcca gaaccatacg taccatcttc aaaaaactcg gaatattggc
    12181 actctggaca ataataatga ggggctaacg gattaacttc agtgattcct gtcatcgtcg
    12241 caacaaagct agagccaaca gagccacgtg aacctactag atagccatct tcattacttt
    12301 tatgcactag tttttgggcg atcagataaa taaccgagaa gccattacca ttaatagaat
    12361 tcaactcttt ttttaatcgt ttttgaatga tctcaggtaa cggatctccg tacatttgtt
    12421 ttgcttttgt gtaactcaat tctgatattt catcttctga acctggaatc ttcggtgtat
    12481 aaagttcatc tttgactgga atcacttctt cgcagatatc tgcgatttta ttcgtatttt
    12541 ctactacgat ctctttcgct gtttcttccc ctaaaaagtg aaatgcagtt agcatctcat
    12601 cggttgttcg gaaatggaca tccggcaaac tatgacgatt caacggattc gctccgccca
    12661 tagaattgat caaaattttt cggtaaatgg catcttcttc gttcagataa tgtacattac
    12721 ctgttgcaac aacgatttta tccaaacttt ttccgatttc taccaaattt tggataattt
    12781 cttccaaatc atgttcattt tttaccaatt cttgctcgat caaaggcgca tagaccgctt
    12841 ttggcataac ttcaatataa tcgtagaatt ttgctcggtt tcttgcctct tctacccctt
    12901 tttgcatcat ggcttcgaat atttctccct tatcacaagc tgagccgatc aatagatttt
    12961 cacgcatctt tttcaattgg gagcgtggta ttcgtgggac gcgttcgaag tattcgacat
    13021 tcgacattga aatcagtttg aacaaatctt tcagtcctgc ctgatttttt gctaaaatcg
    13081 ttacatggaa aggtcgagcc cttttgtaag aatctccttc tccgatatgc tcatttagct
    13141 gatcatgata aagcatgtta tgattgtcca ttgcctcttt cacaaagatc catgctaagt
    13201 gaccagttgc ttcagcatca tagattgctc ggtgatgctg ttccaagctg acaccaaatt
    13261 ttttagataa cacacctaat ccgaaacgtt tgaattgagg atacagatat ctagctaatt
    13321 ccaacgtatc aatgactgga ttggccgctt caggaatacc ataccttgcg tagctagtat
    13381 tcaagaaccc catatcaaaa gccgcgttgt gggctaccaa aattgtatct tttgaaaatt
    13441 caaggaacat ccgcaatact tcttcttccg actttgatcc tcgaaccatt ccatccgtga
    13501 taccagtcag atctaccgtt gttcgtgaca aaggatgtcc tggatcgata aattcatcaa
    13561 agctttcgat cacatttcct ttatacattt tgactgcggc tagctcgatg atcgtgtcat
    13621 atactgcaga caatcctgtc gtttccacgt caaatacgac atatgtggct tcactcaatg
    13681 cttcatgtgc atcattataa gcaattggga caccatcatc tacgacattc gcttccacgc
    13741 cgtataagat tttcacacct gctttttttc cagcactatg tgcttccgga aaggcttgcg
    13801 caccaccgtg gtctgtaatg gcgatagctc ggtgtcccca tttccctgct tgtgccacaa
    13861 gatcagagat gctgtttgtt gcatccatcg tactcatatt gctatgaaca tgaagctcta
    13921 ctcgtttttc cccttcagga gcataatctt tgcgaggtgt atgtttgact tctatgatat
    13981 cttgcgcatt catgaccaaa tcacggacaa acgtatcttc ttgaatactt cctcgtacct
    14041 ttaaccagct accgacactg atcgcatcaa atacttgttc atctttttcg ccgttcgaga
    14101 attttttgac gataaatgat gaagtataat ctgtgatttt caaagtcaag atcttgcgtt
    14161 ttgaacgtag ttctctgact tctttgtcga atacgtaccc ctcaagtgtg actcttcgtt
    14221 cttcttcaac gatactgatc attggtgtcg ttggttcatc ggctggaata tttcgtccta
    14281 gctggatgtg gatgggtcct tcaagagctg gcgattgctc ttttctttcc tttttctttt
    14341 gttcgtggac aactagactt tcagctgctt gcttcataaa ggcttctgcc tgttcttgtt
    14401 tgcgttcttc aaaaagtttc aatactcgtt ccgcttgctg ctcatccact tctggttcga
    14461 tacgaaattt tgggaatccg taactgacga acaactcttc tactaatggc aagtattgtt
    14521 gcttcaaata agaaatagct cctgtactgt cgattggcaa gatgacttta cgatctttta
    14581 tcacaggtac ctgcgttttc aatacttgct gtgctagtgg tgtatcgcat tgctgatttt
    14641 ccaaagcttg ggcccagtaa tcttgcaaga gctgttcatc gaatgtctgg tcatctgcta
    14701 agatattcag tttgacttgt gcaatatctt taaaagcgat agtcagatgc tgagtcaatg
    14761 accgatatag cataataggc aaaattttgg aaaaatgcag cgtaaattcc cataaacgcg
    14821 atttacgatg gaccactaca ctatccattt caccagcagt aagcagtgga tgattttttt
    14881 ctgcttcctc tagttggatt tgttccaaca gtttttcaaa taaatctcgt ttttctgaca
    14941 aagatatacg ccctttctga tgagaaacaa tgcaattgat cgcatcttat cctcttcttt
    15001 ttcagtacct tttagtatac tcgttttttc tgagttttac attaaaaaat tggaactgcg
    15061 attcaaatcg cagttccaat tttaaaagcg aatcatcaga ttgtcaaaaa cagctgattc
    15121 agctattttt attttctgtg ttttaacgct tattattcgc cttggttcaa gaggattggt
    15181 aaagtattca ccaattcttc tttacgtact tcaaccattt cgccagtttt cttgattttc
    15241 acttctacga ttccatccac tgctttttta ccgacagtga ttctgattgg acagccaatc
    15301 aaatcagaat ccgcgaattt cactcctgcg cgttcatttc tgtcatcaac cagtacttca
    15361 tagccagctt ttgtcatcgc ttcttctagt tcattcgtca ggtttgtttg gtattcgtct
    15421 tttagattca tttggacgat atgcaaatca aatggcgcaa ttccttttgg ccagttgatt
    15481 ccttgttcat ctgaatgttg ttctacgatt gctgataata aacgacttac accgatacca
    15541 taacagccca taatcacaaa tttttctcgt ccattttcgt ctagtacagt tgctcccata
    15601 gattcactgt aacgagtgcc gattttgaag atatgtccga tttcgattcc tcgagtaaag
    15661 gcaagaacac cattgttgtc tggtgaagga tctccttctt gtacaaaacg aagatcttca
    15721 taagaaagta cagtgaaatc gcgttctgga ttcacatttt tatagtggaa tcctgtttcg
    15781 ttcgctccag taatggcatt cgctaaatct tggacataac ggtctgcata tacttttacg
    15841 tcatctgaaa caccgactgg tccgacagaa ccaaactcag cacctagata tttttgtgct
    15901 tcttcttctg ttgcttcttc taaaaagtca gcagataaaa agtttttcag ttttacgtca
    15961 ttgacttcat ggtctccgcg taccaaaaca aggacaggtt gttcatccgc aatgaacaat
    16021 acagacttga tgattttttg aggttcaaca gaaaagaaat ctgctacttc gtcaattgat
    16081 tttacgttag gtgtagctac tttctccaat tcaagctgtg tttcatgcga tttttttgat
    16141 acatagtagc ttgtagccat ctccaagttt gcagcataat cactttcagt cgaataacag
    16201 atcgtatcct ccccgatttc tgagatcgcc atgaattctt ttgagtcttt cccgcccatt
    16261 gcgccaccgt ctccgataat cgagcgaaat tctaagccac aacgcttgaa tacttcggtg
    16321 taggcttttt cgtaatcttt atatgtctcg tccaaacttt cttccgttgc atggaaagaa
    16381 tacgcatctt tcatgataaa ctctcttccg cgaagcaaac cgaagcgagg tcgtttttcg
    16441 tcacgatatt taggttggat ttgataaaga tttaaaggta atttcttata tgaattgatt
    16501 tcattacgca tcaaatcagt aaaagtttct tcgtgagttg gtccaaggat catttttcga
    16561 tcattgcggt ctttgaaacg atacaagttt ggtccatatg tttcgtaacg cccggattct
    16621 tcccaaagtt ctgctggcaa gatggcaggc atcagcattt ctaccgctcc gattttttca
    16681 aattcttccc gcataatgcg tttcagtttt tccaatacac gatttgctaa tggcagatat
    16741 gaataaatac ccgctgatac ttggcggata tatccagctc ttagcaagat ttgatggctt
    16801 aatacttctg catcatttgg aacttcgcgt aatgttggaa tcaacatttt tgattgtctc
    16861 attctatata ctcctttatt tcctcaaaat agttatcgtt tgttattata ccctatttgt
    16921 caactttttc tagaaaaaga atcgttgaat atcgttccat gtaactagca ccatcaacaa
    16981 cattaaaaat ccaaagccag ctaatgtcaa tattccttct ttttcttgac ttaatggttt
    17041 cccgcgaatc ccttcaaaaa tattcaagac taatttcccg ccatctaagg caggaatcgg
    17101 aagcagattg acgattccga gattcattga aagaagcgcc atcaaactaa taacagttgt
    17161 tacaccttga tttgctgctt ctgaagacaa ttggtacatc atgacaggtc cgcctaattt
    17221 atctaaactg aaacctgtaa atagtgatcc taaggctttg aaaatttcca atgaaccgct
    17281 gaaagcttga cgcgtccctc caatgatctt atccataaaa cctgtattca ttggggcttt
    17341 tataccaagt tggccaactt tttcgccatt tgactctaca gatttcggtg tcacgtcgac
    17401 agattgcacc tgaccttctc gttcgatctt aaagtctaat gttttatccg gatttttcgt
    17461 aatgactgtt gtcagatcat tccatgaatg gatttctttt ccgtccacac tgactacctc
    17521 atcattttct tttaagcctg cttctgccgc agctccatta ggcatgatct ctcctacgcg
    17581 attagtgttc gtcacttgaa caccaccttg cataaatgcc agaatgatga ataacaggat
    17641 tgccaaaata aagttattca tgggtccagc aaagttggtc agcatacgct gccacaattt
    17701 agccgattgg aactgtacgt cttttggcgc aattctgatt tctgttccgt cgttttcaat
    17761 aatcgtcgca tcgtgatcaa cagggtaggt tactacttct gtttcgtctc cattcacata
    17821 accagtgata gtcagctcat cttctaaatc ataacggctc aattccatcg ggatagcatt
    17881 tgtcaattgg attttcttac ttaaatttat cttctctacg atgccgtcag aatttagtaa
    17941 aagagaaaga ggcattcctg gtgccatttc tgtttcatca tccccattgc ctgccattcg
    18001 aacataaccg ccaataggta ataggcgaag cgtatatgtt gtcccgtctt ttgcttgatg
    18061 cccataaatt ttcggaccca taccgatagc aaattcgcga acgaggattc ctgatcgttt
    18121 cgcaaagaag aaatgaccaa actcatgaac aatcactaat ataccaaaaa cgatgataaa
    18181 tgtcagaatc gttttcatag cttttttctc ctttacttgt tttttgtgtt ttttataaaa
    18241 caacgataaa acactataat tttaccatag tataccaaag acaccaatag tatcaatata
    18301 atgaaaaata aaaacctgcg tcttttatga aattcacaaa gaaacgcagg tatacttact
    18361 aaataatgcc aaataaatgc atgataggaa atacaaacag caaactgtcg aaacggtcta
    18421 agattccacc atggcctggt aagatatttc ccgagtcttt cacatcataa tgacgtttga
    18481 ttgcagattc gaccaaatca ccaaattgtc cgactgctga aaaaataatc gtcatcagaa
    18541 gcatgacaaa cataccatga ttaaatagtt cttttgctgg gtatagcaat aaataaagaa
    18601 atgcgactac aacagcacta ccaataccac cgagcgcacc ttcaatcgtt ttgttgggcg
    18661 aaatatcagg acttaactta tgctgaccat aacgtcgacc aaccatatat gctccgatat
    18721 cagttgccca aacaataaat agaccaaata tcaaaacagc caagctttct gttcgtgcat
    18781 tgacaaaatt ctggaaacct attcccacat acaagctgac aagcacagga aaacctgctt
    18841 catcaatcgt atacgtattt ttagaaataa ctgatgttcc taaaagaatc ataactataa
    18901 gataaaataa cataaatgta cttacattct ctggaagaaa gaaaaaccat ctttcttttg
    18961 gcaaaacaag taacactgca ccaacggcgg ataaaactcc ttcaaaactt aagagtgtca
    19021 atcctttcat ccgaaacagc tcgtaaactc ctattactgc taagattgct gctgtaagct
    19081 caaccgctat gcctccgatc catataatcg gaataaacaa gactagcgcc acggctgctg
    19141 tgaccacacg ttgtttcatg actgatcccc tttctcatct tctgtttttt ttacaccgcc
    19201 gaatcgacgg tctcgatttt gataagaggc gattgcttct tcaagatgcg caccatcaaa
    19261 atcaggccaa agcgcttttg taaaatacag ctcactatat gcgatctgcc ataacagaaa
    19321 attactaatt cgctcttctc cacttgtacg gatcatcagc tcaggatctt gtaactcttt
    19381 aggcaagaaa cctgtcatta aatgcttagc aatcaattca tcatcgattt cttctgcgtg
    19441 tatttctcct tttgctactt cttcggcaat ttcttggaca gcagtcacga tctctgctct
    19501 gcttccataa ttcaaagcaa aattcaatac cattccagta ttgttttttg tttgctcaat
    19561 tgcacgtctt acagcatctt gcgtatgttc tggcaatacg ttttcataac ccatgacatg
    19621 aactttgaca ttttctttaa tcaattctgg tacgaacgta tcaaagaagt cgacaggtag
    19681 ttgcatgaga aaacttactt catcttttgg tcgcttccag ttttcagtcg aaaaggcata
    19741 aagcgtcaac actttcactc caagccttga tgcttttttt gtgactttct ttactgtttc
    19801 catgccttct ttatggccag caactcgtgg caaacgacgg ttttgcgccc aacgaccatt
    19861 gccgtccatg atgatggcaa tgtgctgagg aattggtcca tcggtattaa attgaaattc
    19921 gcttttttct tgaatatatt tgtttttttg cggaaaaaaa cgtaacattc tttttcctcc
    19981 tatacttaaa agattcccac tatcttaagt attatagcaa tatctaactg tttttcctat
    20041 gaaatcattg tttttttatt taaaaactga ataatttttt ctttttttaa tttttaaata
    20101 aaagaaatat aaataaaaac agaggaagcg gaatgatccg cccctctgtt tttatgattt
    20161 tattaaactt ccaataattc tttttcttta tcagcagcga tcttatctac ttctttgatg
    20221 ctgttatctg tcaatgtttg tacgtctttt tctaatccgc gcaaatcatc ttcggtaata
    20281 tcaccatttt tttgttgttt tttatattca tcgatcgcat cacgacggat gttacgaatc
    20341 gcgatttttg cattttctgc ttctttttta acatctttag ctaattcttt tctgcgttct
    20401 tctgtcagtt gcgggataac taagcgaatg acatttccat cattggttgg actgattccg
    20461 atatcacttg ccataatagc tttttcaaca tcttgaagaa tgctcttgtc aaaaggtgtg
    20521 atcattaaaa cacgtgcttc tggaatttgg attgatgcca tttggttcaa tggtgttggc
    20581 gcaccgtagt agttcacagt aatacggtcc aaaaggctag cgttcgcacg gcctgcgcgg
    20641 atttgcccaa gttcacgttg aagattttgt gctgcttttt tcattttttc ttttgcttct
    20701 gtcataattg catctgccat ttttatttcc cccttacagt tgttccgata ttttcgccta
    20761 agattgcacg gcgaatattt ccgtgttcat ttaaattgaa gacaagcagt ggaatatcat
    20821 tatccatgct tagtgaactt gcagttgaat ccatgacttg taatcctttg gcaataactt
    20881 ccagatgagt cagttcttca aattttactg catttgcatc tactttcgga tcagcagaat
    20941 aaacaccgtc tacattgttt ttagccatca ggataacatc tgcgccgatt tctgccgcgc
    21001 gtaatgctgc tgttgtgtct gtcgagaagt acgggttgcc ggtaccgcct gcaaagataa
    21061 cgatccgtcc tttttctaaa tgacgttctg ctttacggcg aatatatggc tctgcgattt
    21121 gacgcatttc aatcgaagtt tgcacgcgtg tcggtacacc cacgttttcc aacgtatcct
    21181 gtaaagctaa ggcattcata actgtagcta acatacccat gtaatcagct tgagcacgtt
    21241 ccatgcccat ttgtgctccg atttgtccgc gccagatatt tccgccgccc acaacgattg
    21301 ccatttcaac gcccagctcg tgaacttctt tgatttcttg gatgatttct ttgattactg
    21361 gtggtttgat tccaaatcct gcgtccccag ctaaagcttc tccactcaat tttaagacta
    21421 cacgctgata tttcggtgtg accatgttca ttcctccaat attttctatt gccattttac
    21481 catacttaga tgatttcgac actctaagac tggtttttct tgttttgctt aaaaaaaggg
    21541 agcgcacaaa ccgtgcgttc ccgtctgtta ttcaacagaa ttattttttc acttggctca
    21601 taacttcttc tacaaagtta tcttcgcgtt tttcgatacc ttcgccaact tcgaaacgta
    21661 cgaatgtttt aacagttgcg ccttttgatg caacgtattt ttcaacagtc atatcaggat
    21721 ctttaacgaa tggttggtcc accaaagcga tttctgcttt gaatttcttc aagcgtcctt
    21781 ctaccatttt ttcaacgata ttcgctggtt tgccttcgtt caatgcttgt tctgtaagaa
    21841 cagttttttc atgttctaat tcagcttctg gaatttgtga ttcgtttaca taacgaggat
    21901 tgatagctgc tacgtgcata gctacgtctc ttgcaactgt ttcgtcagtt gttccatcta
    21961 gaacagtcaa tacggcaata cgtccgccca tatgcaagta tccaccaaat gcagcattgt
    22021 cgtctttttc tacaacttca aagcgacgga agctgatttt ttctccgata acttgagttg
    22081 cttcgatcaa gtcagattca attgtacctt tatctgtttt gattttcatt gcagcttcca
    22141 tgtctgctgg tttgttttca gcaacaagtt ctgcaatttc ttttactaaa tcttggaaca
    22201 tttcgttttt agaaacaaag tctgtttctg agtttacttc aacgattgct gcagtgttac
    22261 ctttcacagc aactgaagcc aatccttcag ctgcaatgcg gtcatttttc ttcgcagcct
    22321 ttgccattcc tttttcacgt aaaagatcaa ctgctttttc catgtcgcct tctacttcaa
    22381 ctaatgcttt tttcgcatcc atcattccta cgccagtcat ttcgcgtagt tcttttacca
    22441 ttttagctgt aacgtctgcc atgtttaact cctcctgtgt gtttttcttt ttaaaaaaag
    22501 ctgcttcaaa ggagagtgag gcttgtcgcc cagcctttga aacagctcca tcattcaaaa
    22561 ttattctgct gaagaattgt cgccttcaac aacatctacg atttcttcga ttgatgttgc
    22621 tgtgttttct tctgtgaaat cttcttcaac tacttgatct tcaccttggt ttccttcgat
    22681 gaaagcatca gccatttttg aagtaatcaa tttaacggca cgaattgcat cgtcgtttga
    22741 agggattact acgtcgattt catctggatc gcagtttgta tcaaccatag ctacgattgg
    22801 gatatttaat ttgtgtgctt cttgaacagc aatacgttct ttacgtgggt caacgatgta
    22861 cattacatct gggattcttg gcatatcagc gataccgcct aagaattttt caagacgttc
    22921 acgttctttg ttcaaaccag caacttcttt tttaggtaga acttcaaaag ttccatcttc
    22981 ttccattgca ttgatttgtt tcaaacggct gatacgtttt tggatagtat cccagtttgt
    23041 caatgttccg cctaaccaac gatggttaac gaagtattgt cctgcacgag ttgcttcttc
    23101 tttgattgct tcttgtgctt gtttttttgt acctacgaat aatgctacgc cgccttcttc
    23161 agcaacgctc ttcatgtaat cataagctgc atctactaat ttaactgttt tttgcaagtc
    23221 aatgatgtag attccgtttc tttctgtgaa gatatatttc ttcatttttg gattccagcg
    23281 acgagtttgg tgaccaaagt gtacgccggc ttctagtaat tgtttcatag aaattactgc
    23341 catgtttgtt tcctccgatt tggttttatt tttcctcttc ttatcttcta ccttgccggc
    23401 aaactttttc aagcacctac cgacaatcca ataagaatgt ggatttgctg atgcataaag
    23461 caccctcagc tattatacag acaaaagatc cgtatcgcaa gagcaaatat acttttctgc
    23521 tcaacattca atagtttacc tgaaagataa aaagaattca agaaaaacag tagatttctc
    23581 tttgtttctt tattatcctt tttccataaa ataattttag gtataaaaga cgaatattat
    23641 tgggcaatcc ttcttttttt tgttatgata catgtgaaat ctttcgtaaa ggagaaagaa
    23701 aatgcgcaaa gctcaaagac atttgctgat taaacaagtc attgaagaat tcccgatccg
    23761 tacgcaagaa gaactattaa acaaacttgg gcattatggc gttaccgcca cgcaggcaac
    23821 gatttctcga gatatccgtg atctaaaaat cgtgaaggca cctgatgaaa atggcgtttc
    23881 ccgcttcgta ttgtttcgcg aaaaaggaac tcctgagact aggactgagg aagaggatcg
    23941 gctggttcaa atgattgaag acattgtatt gaaagtcgaa cgagtccact ttttgacgat
    24001 cgtcaatacc ttgccagaca atgctcattt atttgcatct gttttagatg agatcaaacc
    24061 tccctctatt gtcagtacaa ttgctggatt cgatacgatc atggtcatct cggaaaatga
    24121 ggaggacgca aaacgagtag aagaatttct tcaccatcca actgaagtat cactttttta
    24181 atcagagcac gtattcctaa tatggaatgc gtgttttttt attttcaata ttttccttat
    24241 tgaataaacc tttacactct ttacaaaaat acatcatttt ttattcaaat ttttcaacac
    24301 cttgattgaa tcacaataat catcatttat attggatgtt aacaagagca gcttcttgct
    24361 ctttgtgtat ttcaaaaaag aaatgaaagg aaatcatatg tataaattat taacttctgg
    24421 accattgacg acttctgaaa cagtgaaaaa tgctatgctg atcgatcatt gtacttggga
    24481 tcaagaatac aaagaaatta cacaatggat aagaaaaaaa ttattggatc ttgctcaagt
    24541 atcggaagga atatacacaa cggtcttaat gcaaggtagc agctccttcg gggtagaatc
    24601 ggtattaagt tctgtgatca ggccagaaga tactgtactg atttgttcaa acggcgcata
    24661 tagacaacga atgatcaaca tgtgcgaatg tctgaaactg aactataccg tttatgaggt
    24721 atcggaacat caaatcctcc aagctcatgt gattacacag ctgattgaag agaatccgtc
    24781 tatctccgca ctagcaatgg tccatagcga gactacttcc ggtattttga ataatttgga
    24841 agagattgct gctgtcacac aagaaagaga tcttttgttt atagtggacg cgatgtcaag
    24901 ctttggtggg ataccgattt gtgtagccga actagggatt gattttttga tttccagctc
    24961 aaacaaatgt attcaaggtg ttccaggctt ttcttttgta cttgctaata aagcggaact
    25021 ggaaaaacga aaaaatgtta gccgaagttt gtcacttgat ctatatgacc agtaccgcgt
    25081 gatggaaaac gagaatggca aatggcgttt cacttcccct acccatacgg ttttggcttt
    25141 tcaacaagcg ctgaaggaac tagaggcaga aggaggaatc gaaactcgat attcacgtta
    25201 tctcgccaat aatcatgtgc tacgacaaaa aatgacagag atggggttcc agcctttcat
    25261 tcaagaatat caggggccat tcatcacctc ttttctttac cctaaggact ggcgatttga
    25321 ttttaatcat ttttatcagt atttaaagca aaatggattt gtgatctatc ccgggaaaat
    25381 cagcgatcat gaatgttttc gtatcggaaa tattggcgag atctatccgg aagatatttt
    25441 ggaactgaca gcaattatca aagactataa ggagaacgtt aatgattaaa actgtaattt
    25501 ttgattgggc aggaacaact gtggactttg gctgtatggc tcctgtccac gcttttagaa
    25561 atgcttttct agaaaaagga atccaactga ctgacaaaga aatccgctaa ccgatgggaa
    25621 aattaaaatg ggatcatatc caacagcttc tttccctccc ttctgtcaaa aaacaatgga
    25681 tagctattta tggacaacta cctcaggaaa aagaggtgga ggaattgtat caacaatttg
    25741 aacattatct gtttaaagat ttggtcaagc attctacctt gaaacccgac acattggaaa
    25801 cgatcgaacg gttgagaaac gctgggatca atattggttc cacgaatgga tttaatgctc
    25861 ctatgatgac aatcgtagca gaaaccgcaa aaaaagaaag gtattcacca gacttcatgg
    25921 caacttttga agacgtcgaa gggtatggtc gaccgtttcc ttatatgatc cataaaaaca
    25981 tgcagtactt caaaaacaag tcggttgatg aagtaatcaa agtcggagat acggtctcag
    26041 atatccagga agggaaaaat gccggagtgt tgacagtagg tgtaattgaa ggtagttcgc
    26101 taatggggat ttcttatgat gagtaccaaa aattagagat ggggaaaaag atcgtttaaa
    26161 acagtctgtt gctcttagat tccaacaagc cggcgctgat atttgtgtaa acaatttaaa
    26221 agagttaaca gaatacattt tgtacgctga catgaatcca gaatgacttt tatacaaaat
    26281 aagaggttgt gaaaaagctg tcctgtatca agtaataaaa acagccaagc aaaaatagct
    26341 cctcatattt ttcgtttggt taggcttatt accgcagatg caagcttttg aacaccgttt
    26401 attcgaaaaa aaaaagggag ctgtgacacg acttttgtca cagtcccctt atttgcaaac
    26461 aaacagtgtt taagagacaa cctctccact aaacggtgtt cattcagctg actctcggta
    26521 tttgctcaaa aaacgataaa atttgaaaag ctattttctc ttttgtttct ctaatactcg
    26581 gatcagaacg ctgatttcac attctctttt tcttacatct tatctggtgc atgaagtcct
    26641 agcaaacgaa ggtcttcttt caataataca gtcactgcat aaactagagc taagcgtgct
    26701 tctttttgtt catcatcagc taaaatcttc gtatgagcat agtatttgtt gaatgcttgt
    26761 gctaatttga ttgcatgttt cgcaatcact gacggttcgt atttttcccc agcagacaag
    26821 accgtttcag ggtatttttg aactaattta accacttccc agctggtatc gtcattcaat
    26881 gcatagtctg ctgtttctga agggacaaat cctgcttttt ccaacaggct gactgcacga
    26941 gcatgtgtat attgcacata aggtccagtt tctccttcaa atcgaacaac ttcttccagg
    27001 ttaaagtcaa atgtattcag tcgatcgttt ttcaaatcgt ggaaaatgac tgccccaacc
    27061 ccaacttgtt tagctacagc atctttgttt tccaaatcag ggtttttctc gctgatttgt
    27121 tctttagcag attggattgc ttcatttaat acttcttcta ataagacgat ctttccttta
    27181 cgagttgata attttttacc accttgcgtg atcaaaccaa atggaatatg gtgcatgtcg
    27241 tcagaccagt caaagcccat ttccttcaag acagctttca actgtttaaa atgatagctt
    27301 tgttcattcc ctactacata tagagattgt ttgaagtcgt aagtacgttt acggtacaat
    27361 gcagcagcta agtcacgtgt aatgtatagt gtcgcaccgt ctgacttctt aatcaacgct
    27421 ggattcaggt cataagcaga taggtcaacg atctctgcac ctttatcctc gttcagcaaa
    27481 tgtttttctt ctaaaagttt gacgatttca tccatcttgt cattgtagaa agcttcaccg
    27541 ttcaacgaat cgaaacgtac ttccagcaga tcatagattt tattgaattc tttcatcgat
    27601 tcatcacgga accattgcca taattgaata gcctctttat cgccttcttc cagacgtttg
    27661 aaccaagcac gagcttcttc atttaattct ggttctgttt cagctacttc atggaattgg
    27721 acgtataaac gaagcaattc attgattggt tctgctttaa cagcttcttc tgtaccccat
    27781 tttttgtaag cgacgatcag ttttccaaac tgtgttcccc agtcacctaa atggttgatg
    27841 cggattggct gataaccgat tttttccata atgaaaccga tcgaattacc gataactgtc
    27901 gaacgcaaat gtcccattga gattggtttg gcaatattag gagaagacat gtcgattggt
    27961 actgttcctt gattcccgat gttgctatcc ccataatgtt ctttttcttt cactactgtt
    28021 tgcaaaactt ttttgctgat aagttcttta ttcatgaaaa agttcaagta aggtccgaca
    28081 acttcgattt tttcaaagtt ggcagaatcg attttttctg ctaaatctgc agcgatttgc
    28141 tgtggcgctt ttcggtaaac ttttgctaat gaaaaggctg gaaatgcaac atctccgtgt
    28201 tcagctgatt ttggattttc tagtaattgc tcgacttgtt ccagtgttaa atcatctttg
    28261 acagcgtcat agacagcttt tgcgacaaga tctttattat tcatctttat tcctcctaaa
    28321 gtgttccctt gattgttaaa caaaaaaaat ctctagcgac ggcatactta gtatgccatc
    28381 actagagacg agatttcccg cggtaccact ccaattgtcc taaaaaagga ccagctccat
    28441 ctgatatcgg tagacgaccg tctgtttaaa acagaattct ccaagtgcgc ttcgttgtat
    28501 cttcttcatt cggcttccac cacttccgaa ttcgctagcc aagaatgata caagtactct
    28561 cttgttcaac aaatcttagt cttattaaac tttcttgaat tatatcagaa aaaaaaacga
    28621 aaggctagtc gtttcataaa aaaacaatcc agatggccta aaggagaaga aataccacct
    28681 ggatagctat aaatcatttc gtaaatacga aagacttaac aaattaatca gctacgataa
    28741 tcgttccttc ttcagaagct aaaagattct cgatattttc taaagaagtg atgattgcct
    28801 tagcgtttgg ttttgcttca acaaatgcaa tagctgcttc tactttcgga agcatgcttc
    28861 ctggagcgaa ttgcttttca tcaatgtatt gtttcatttc tgaaacagta acagtttcta
    28921 atttcttttg atctggtttt tggtaattga catacacatt gtctactcct gtcaatacga
    28981 tcagcaaatc cgcatcgatg atttcggcta atttttctga agcaaaatct ttatcgatta
    29041 cggcttctcg tccttctaat ccagtagctg tttctacaac aggaatccca ccgccaccaa
    29101 cagagactgt gataactcct tgatcgacca gcgtttcgat gacacgtgct tctttaatcg
    29161 agatgggttt aggggaagcg actacttttc tccatccacg tccagcatct tctttgaatg
    29221 tcacagtgga gtcagcattc atttgttctt tggcttcttc ttccgtgtag aatggaccga
    29281 ctggtttact tggatttttg aatgaaggat cattttcatc cacaataact tgagtgacta
    29341 aagaaaccac atctttatcg atcccttttt ccttcagtac ttcgcccatg gcgttttgta
    29401 accagtaacc gatagatcct tctgtcattg caacacatgt atctaaaggc attgccggtg
    29461 ttttctcaga atcagcagct tgctgctgaa tcaataggtt accgacttgc ggaccatttc
    29521 cgtgggagat gatcaattca tctccttgtt cgataaattt cactaaatac tttgctgttt
    29581 ccattaacgc ttcttgttgg gcttttgcac ttgcatccgt agacaagatg gcattgcccc
    29641 ctaaagcgac aactactttt cgtttggcca tttcattcgt cctttcttca gttctaccga
    29701 attttctaga taacaaaacg agccagcgtt ttgtgatttt ccctcaatgc tgactcgttt
    29761 tttcgtgaga tgaatgtggt tatgcttaaa cgcgagggat aaacaagtta cctaatgttg
    29821 ctgccatgat cgctttgatt gagtgcatac gattttctgc ttggtcaaat tgacgagcat
    29881 atttgctgcg gaagacttca tctgttactt ccatttcagt gatgccaaag cgttctttca
    29941 tttgttcacc gtaaacagtg tttgtatcat ggaaagctgg caagcagtgc aagaagatca
    30001 aacgatctgt gttgtgtgtt ttttctacca tttccatatt gatttggtaa ggtttcaaca
    30061 atttgatacg ttcttcgaat ttatcttctt cacccattga tacccataca tcagaataaa
    30121 ggacgtctgc tccgtctaca cctttatcaa catcgtcggt aatcatcaat tgtgcaccgg
    30181 atttttcagc aaagccttct gccattttga cgatttcttc ttcaggttgt aattcttttg
    30241 gtgcaacgat acgcatattc gctcctaaaa ttgcacctgt gactaataaa gagttagcca
    30301 tattgtttcg accatctccg cagtaagcaa cagtgatacc ttctactgtt ccaaagtttt
    30361 cttggatagt taaaaagtca gcgatcattt gtgttggatg ccattcatca gtcaagccat
    30421 tccaaactgg aacaccagag aattctgcta gttcctctac cattttttga ctgaatccac
    30481 ggaattcgat tccgtcaaac atacgtccta gtactttagc tgtatcttct gtggattctt
    30541 ttttacctaa ttggatatca tttgcaccta gatattcagg atgtgcacct agatcgatcg
    30601 ctgcagtagt aaatgcagaa cgagtacgtg tagatgtttt ttcaaataaa agcgcaatat
    30661 tttttccttc tagatagtga tgtgggatac cacgtttttt caagtctttc aagtgttctg
    30721 aaaaatcgat caaatattgt aattcttctt ttgtaaagtc tttttctgct aataagcttc
    30781 ttccttggaa tactgattct ttcatattaa acattctcct ttagattgtt tttatttaag
    30841 attaaagagg aaatcccgac ggcagctgac agtaagactg ccgtcaggaa acaaattact
    30901 tcaagtcttc acggacaagt ggttggctca tgcagcgtgg accaccacga cctcgtgaca
    30961 attcacttga attgatttct aacactttga tgccatagct acgaagcaat tcgttcgata
    31021 cataatttcg gttataagtg actacaacac ctggagcgat tgccaatgtg tttgatccat
    31081 cattccattg ttctcgaggt gcaacgatct catctccatt accagttggg atcagtacaa
    31141 gatcatctaa tccaagagca gctttcatcg tttcgtgtaa gttatctgaa tgagtaatct
    31201 tgatatcatc accatctggt tcgattgtaa agacatccat cttaccgtct ttactttgaa
    31261 ttgctggatg gatagtgaat ttatcgtgat ctaccattgt aaatacggta tccaaatgca
    31321 tcattgcacg gttgttcgga attttgattg ccaacacttt ttcaaatcct gaattttttg
    31381 cgaataggtg gcgtgctaat ttttctaaag ctttcgcatt agttcgttga gaaatcccaa
    31441 cagctactac tttatcgctt aagatcaatt cgtctccgcc ttcgatatga tctggatttt
    31501 cacgatccaa ccatacttcg attcctttat ttgcaaatct tggatgatgt ttcaaaatat
    31561 attctgtaaa catcgattca cgacgacgtg cttcaaaagt catcttattg actgtcatcc
    31621 catttcccat tgatgcggaa gggtcgcgtg taaagtacaa gtttggcatt gggtccatgt
    31681 aaaatggata gtcatcgtct gctgacagat catatagact gctagaacgt acttcgatat
    31741 cttttgtacg aaccccagcc atgattttat ctaccatttc ttgcgtttcc attgatagaa
    31801 ggaactcatg aagaccctct cttacagcat tcgatgcaat atgagattca tccaacattt
    31861 tattcaagaa ttgttctttg acattgcctg cgtcaatcgc ttctgccgct aatttttcca
    31921 agtaaagagt ctcgacgcct tcattttgca atgtcttcgc aaagttgtca tgttcttctt
    31981 gagcaatcgg aagatatgga atatcatcga acaacagacg atccataata tctggtgtca
    32041 aattttccac ttcttgtcca ggccgtttca gtaaaactgt ctttaatttc cctatttcag
    32101 agaaaacgtg aataggttta tccatgttgt gttgcctcct tctttttgat tacatgtata
    32161 ggatatcctc cttttgtaat cactttcata attttgtctc attcaaaatg agacattcct
    32221 cacattaata ttcgataatt aaataattaa acgtttttct atttttaagc gtaatttatt
//
LOCUS       DAFLWC010000025        30505 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.025, whole genome shotgun sequence.
ACCESSION   DAFLWC010000025 DAFLWC010000000
VERSION     DAFLWC010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30505
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.025"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(41..3715)
                     /gene="rpoC"
                     /locus_tag="L1V17_001068"
     CDS             complement(41..3715)
                     /gene="rpoC"
                     /locus_tag="L1V17_001068"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBN1235851.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(3773..7390)
                     /gene="rpoB"
                     /locus_tag="L1V17_001069"
     CDS             complement(3773..7390)
                     /gene="rpoB"
                     /locus_tag="L1V17_001069"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBN1235852.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            8118..9086
                     /locus_tag="L1V17_001070"
     CDS             8118..9086
                     /locus_tag="L1V17_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1235853.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            9104..10009
                     /locus_tag="L1V17_001071"
     CDS             9104..10009
                     /locus_tag="L1V17_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1235854.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            10006..10812
                     /locus_tag="L1V17_001072"
     CDS             10006..10812
                     /locus_tag="L1V17_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1235855.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            10948..11937
                     /locus_tag="L1V17_001073"
     CDS             10948..11937
                     /locus_tag="L1V17_001073"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBN1235856.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDVK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(12254..12778)
                     /locus_tag="L1V17_001074"
     CDS             complement(12254..12778)
                     /locus_tag="L1V17_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HBN1235857.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            13065..14762
                     /gene="scm"
                     /locus_tag="L1V17_001075"
     CDS             13065..14762
                     /gene="scm"
                     /locus_tag="L1V17_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBN1235858.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDT
                     SASSDSTDTTSTTSDSTDTSASSDSTDTSTTTSDSTDTSASSDSTDTTSTTSDSSDSS
                     TTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDN
                     RTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
     gene            complement(14917..15903)
                     /locus_tag="L1V17_001076"
     CDS             complement(14917..15903)
                     /locus_tag="L1V17_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBN1235859.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(15926..16492)
                     /locus_tag="L1V17_001077"
     CDS             complement(15926..16492)
                     /locus_tag="L1V17_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBN1235860.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(16506..16922)
                     /locus_tag="L1V17_001078"
     CDS             complement(16506..16922)
                     /locus_tag="L1V17_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBN1235861.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(17379..19313)
                     /locus_tag="L1V17_001079"
     CDS             complement(17379..19313)
                     /locus_tag="L1V17_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBN1235862.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            19594..20550
                     /locus_tag="L1V17_001080"
     CDS             19594..20550
                     /locus_tag="L1V17_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBN1235863.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            20640..21743
                     /locus_tag="L1V17_001081"
     CDS             20640..21743
                     /locus_tag="L1V17_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBN1235864.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            21756..22709
                     /gene="menA"
                     /locus_tag="L1V17_001082"
     CDS             21756..22709
                     /gene="menA"
                     /locus_tag="L1V17_001082"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HBN1235865.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(23523..24869)
                     /gene="gor"
                     /locus_tag="L1V17_001083"
     CDS             complement(23523..24869)
                     /gene="gor"
                     /locus_tag="L1V17_001083"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HBN1235866.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(25003..26256)
                     /locus_tag="L1V17_001084"
     CDS             complement(25003..26256)
                     /locus_tag="L1V17_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBN1235867.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(26262..27185)
                     /locus_tag="L1V17_001085"
     CDS             complement(26262..27185)
                     /locus_tag="L1V17_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBN1235868.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(27406..29898)
                     /locus_tag="L1V17_001086"
     CDS             complement(27406..29898)
                     /locus_tag="L1V17_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBN1235869.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGIPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(29905..30372)
                     /locus_tag="L1V17_001087"
     CDS             complement(29905..30372)
                     /locus_tag="L1V17_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBN1235870.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
BASE COUNT         8816 a         6483 c         5704 g         9502 t
ORIGIN      
        1 gttgtgacaa taatttgtca caacctcttt tttaaaatat ctattttgtt tgattgttca
       61 ttgcgtcttc tgcagccatt tgcgcttcaa tatctgaaat actgtagaca ttttcgcttg
      121 ctacaccgac ttcttttggt tccatgtcac gataacgttg cataccagta ccagctggga
      181 tgatcttacc tataataaca ttttctttca aaccaagaag aggatctttc ttaccgcgga
      241 tcgcagcatc cgtcaagaca cgagttgttt cttggaatga tgcagcagat aagaaactat
      301 ttgtttctaa tgatgctttt gtgataccta gtaagacagg tcgagaagtt gcaggaacgc
      361 ctcctgagac tagcgtattg tagttttgat ctttaaagtc tgcgatgtct aataatgtac
      421 ctggtaagat atctgtatca cctggatcca ttacacgaac tttacgcagc atttgacgaa
      481 ccattacttc gatatgcttg tcgccgattt ctaccccttg catacggtaa acacgttgta
      541 cttcacgaag caagtagttt tcaacagata atacatcgcg aacttgcaac aattgttttg
      601 gatcgattga tccttctgtc aatggtgcac cacggtggat catatcgcct tctgctactt
      661 tcatacgtgc tgtataagga acagtatacg tacgtgtatc tgtttttcct ttgattgtta
      721 cttctttggt acgtgttgca ggatcttctg agatatcgat gacatcccct gttacttctg
      781 tgatcactgc ttgccctttc ggattacgtg cttcaaagat ttcttggaca cgaggaagac
      841 cttgagtgat atcgtctccg gcaaccccac ctgtatggaa tgtacgcatc gtcaactgag
      901 taccaggttc accgattgat tgagcggcga tcgtaccaac tgcttctccg acttcaacgt
      961 cagagccagt tgcaaggttg cgtccgtaac aatgtttgca gacaccatgt tttgtattac
     1021 atgtgaagac agaacggatt gtcactgttt cgacacctgc atcaacgatt tgttttgcga
     1081 tgtcttcgga aatcaattgg tttcctgcaa tgatcaattc atttgtttca ggatgacgta
     1141 cttctttacg ggtgtaacgt cccactaaac gatcttctaa tgattcgatg atttcatttc
     1201 cctcgcggat ggcttggatt tcaagacctc ggtcagtacc gcaatcttct tcacggatga
     1261 ttacatcttg ggccacgtca accagacgac gagtcaagta acctgaatcg gcagtcttca
     1321 aggctgtatc ggtcatccct ttacgagccc cgtgagttga gataaacatt tccaagacgg
     1381 atagtccttc acggaagttc gaaatgattg gcaattccat gattcgacca ttaggagcgg
     1441 ccatcaaacc acgcattccg gcaagctgtg taaagttgga aatgttacca cgagctccag
     1501 aatcagacat catgaagatt ggatttttcg cttccaaacc ttccatcagt ttttgttgga
     1561 tgctgtcttt tgcagcattc caaacagcaa tgacacgttc ataacgttcg tcatctgtga
     1621 tcagaccacg acggaattgt tttgtaatag tttcaacttg tttatgggca ttttcaatga
     1681 tttcttgttt ttcattcagt acactgatgt cagcgatccc tactgtgata ccggcatgtg
     1741 tcgaatgttt gtaccctaag tctttcatac ggtcaagcat cttagaagtt tctgttactt
     1801 tgaatcgttt gaagacttct gcgatgatgt ttcctaagtt tttcttcttg aacggtaata
     1861 ctaattcttg ctctttgata tgtgcaggaa tatcagtacc agcttcaaca aagtatttgt
     1921 ccggtgtttg gacggtcaag ttgaagtctg ttggttcatt cagataaggg aattcaggag
     1981 gcatgatctc gttgaagatg atcttaccaa ctgttgtgat catcgtacgt tctttttgcc
     2041 attcagtaaa tggtttttca cctaatgagt tagggttcac accgatacgt gaatgtaaat
     2101 gaacatatcc gttgcgccat gcgataacgg cttcgttttg atctctgaag accattcctt
     2161 cgccttcgcg tccttcttct tccattgtca agtagtagtt acctagaacc atatcttggg
     2221 aaggagtaac aactggttta ccatctttag ggttcaagat gttttgagca gctaacatca
     2281 acatacgtgc ttctgcttgt gcttcttcat tcaatggaac gtggacagcc atttggtctc
     2341 catcgaaatc ggcattataa gcttcacata caagtggatg caaacggatt gcgcgtcctt
     2401 gtactaaaac tggttcgaat gcttggatac caagtcggtg aagcgtaggt gcccggttca
     2461 gcaatactgg gtgttccttg attacgtctt ctaaaacatc ccatacttcg tcttcttgac
     2521 gttcgatttt acgtttcgca tttttgatgt ttgaagctag ttcgcgttga acaagctcac
     2581 gcatcacgaa tggtttgaat aattcaatgg ccatttcttt tggaagtcca cattggtaca
     2641 tcttcaagaa aggtccaaca acgataacgg aacgacctga gtagtcgaca cgtttaccta
     2701 gcaagttttg acggaaacga ccttgtttcc ctttcaacat atgagaaaga gatttcaatg
     2761 ggcggttacc tggtccagta actggacgtc cgcgacgacc gttatcgatc aatgcatcta
     2821 ctgcttcttg cagcatacgt ttttcatttt gaacgatgat tccaggtgca ttcaagtcta
     2881 acaaacgttt caaacggtta ttacggttga ttacacgacg gtaaagatca ttcaagtcac
     2941 ttgttgcaaa acgtccacct tctaattgaa ccattgggcg taaatctggt ggaataacag
     3001 ggataacgtc cataaccatc cagcttggtt gatttcctga agcgcggaat gcttctaaaa
     3061 tatccaaacg gcggattgca cgtgtacgtt tttgtccttg tgcagatttc aattcttctt
     3121 tcaattcggc tgcttctgca tctagatcaa cattatcaag taattgttta atcgcttctg
     3181 cacccatagc agcttggaat tcttgtccat attgttcacg tttttcgcga tattcgcgtt
     3241 ctgtcaacaa ttgttttttc tctaaattcg tatttcctgg ttcgatgact acatatgaag
     3301 caaaataaat gatttcttcc aaagcgcgtg ggctcatgtc taatacaaga cccatacgtg
     3361 aaggaatccc tttaaagtac cagatatgtg aaacaggagc tgctaattca atatgtccca
     3421 tgcgttcacg gcgaactttc gaacgagtaa cttccactcc gcatcgatca caaacgattc
     3481 ctttataacg gatacgtttg tattttccgc aggcacattc ccagtctttt gtaggaccaa
     3541 aaatccgctc acagaacaac ccttcgcgtt caggttttaa ggtacgatag ttaatcgtct
     3601 caggtttttt tacttcaccg taagaccagc ttctgatttt ttcgggagaa gccaaaccta
     3661 tttgcatact ttcgaattta tttacatcga tcaaaagggg ttccctccat ttcatttaat
     3721 ggcaaaccgc aagacggctg atcttcgacc gccttgcagc tcatagaccg gattagtcta
     3781 aattatcttc tgcggtttca aagttttgga tgacatcgtc tttttcatct tccacttgtt
     3841 cagcagcttt cttttctaat tctttggcag tttgctgttc ggcaaatttt gtcaaagcat
     3901 caacagtgat caaatcgtcg tcttcatcgt ccatgtcgcg aagttcgatc tctgtttctt
     3961 cgatatccaa gacacgcatg tccagaccta gtgattgcaa ttctttcacc aatacgcgga
     4021 atgattccgg tacacctggt tttggaattg gttcaccctt gacgattgct tcgtatgttt
     4081 tcacacgtcc gactacgtca tctgatttgt atgtcaagat ttcttgtaaa gtataagccg
     4141 caccgtaagc ttccagtgcc catacttcca tttcaccaaa acgttgtcca ccaaattgag
     4201 ctttacctcc caatggttgt tgtgtaacca atgagtaagg tccgattgaa cgtgcatgca
     4261 atttgtcatc gaccatgtga gcaagtttga tcatgtacat cacaccgaca gacacacgtc
     4321 catcaaatgg ttcacctgta cgtccgtcgt acagaacagt tttcgcatcg ctggccatac
     4381 cggcttcacg aactgtttcc catacgtctt catcacttgc accatcaaat actggcgttg
     4441 ctacgtggat acctaactga cgtgcagcca tacccaagtg taattccaat acttgcccga
     4501 tgttcatacg tgaaggcacc cctaaaggat tcagcatgat atcgattggt gttccatcag
     4561 gtaggaatgg catatcttct tccggcataa tacgggatac aaccccttta tttccgtgac
     4621 gaccggccat tttatcccct tcatggattt tacgtttttg aacgatataa acacgaacta
     4681 acatgtttac gcctggtgac aattcatctc cagcttcacg agtaaagatt ttcacatcgt
     4741 gaacgatacc gccgccgcca tgtggtacac gtaatgatgt atcgcggact tcacgagctt
     4801 tttcgccaaa gatcgcatgc aatagacgtt cttctgcaga taattctgtt accccttttg
     4861 gcgtgacttt ccctacaagc aaatcgccat cttggacttc tgcaccaata cggatgatac
     4921 ccatttcgtc taaatctttt aatgcgtctt ccccgacatt agggatttcg cgtgtgattt
     4981 cttcaggtcc taattttgta tcgcgggctt ctgattcata ttcttcaata tggatagaag
     5041 tgtatacgtc atcttttacc aaacgacggc tcatgatgat cgcatcttca tagttgtacc
     5101 cttcccaagt catgaaacca actaaaacgt tttggcctag agccatttcg ccttgttcca
     5161 tagatggtcc gtctgccaga gtatcccctt tttcgacttt ctcacccaaa tgaacgattg
     5221 gacgttggtt gtagcttgtt ccggagtttg aacgacggaa ttttgttaca tcgtatttat
     5281 ctaatgcacc gttgtcgcgg cgtacgcgga tttcagaagc atcaacgtat tcaacgacac
     5341 cgtcatgttt acataacaaa gcagctcctg agtcatgcgc tgatttgtat tccataccag
     5401 taccaaccca tggtgcttga ggattgatca acggcactgc ttgacgctgc atgttggcac
     5461 ccatcaaggc acggttggag tcatcgtttt ccaagaaagg aatacatgct gtcgcaacgg
     5521 caactacttg tttaggtgat acgtccatgt agtctacttt atcaatagat acttctaagt
     5581 tttcactttg agcacgagcc ataacaacgt cttgagcaaa tgttccatct tcattcaatg
     5641 ggctgtttgc ttgggctacg atgtaatggt cttcgatatc agctgtcaag tagtcgattt
     5701 ggtcagtaac acgacctgtt tcacggtcta cacgacgata aggtgtttcg ataaatccga
     5761 atttatttac tttcgcataa ctggacaaac tattgatcaa cccgatgttt gggccttcag
     5821 gagtttcgat cggacacata cggccatagt gggagtagtg aacgtcacga acttcataac
     5881 cggcgcggtc acgagtcaat ccgccaggtc ctaaggctga aagacgacgt ttgtgtgtca
     5941 attcgccaag agggtttgtt tgatccatga actgtgacaa ctgagaagaa ccaaagaatt
     6001 ctttgatact tgccacaact ggacggatat tgatcaattg ttgaggtgtc aatgtttcag
     6061 tatcttggat cgacattctt tcacgaacca cacgttccat acgtgctagc ccgatacgga
     6121 attggttttg taaaagttca ccgactgaac ggatacgacg atttcctaag tggtcgatat
     6181 catcgacatt gccgatacct tccatcaagt tcaagaaata gctcattgaa gcaatgatgt
     6241 cggctggacg aaccgttttt acagctgctt ctggatagcc gtttccgatc acgtttactt
     6301 cacgttcagg gtctcttggt gaaaatactt tgatgacttg gacagtcatt ggatctgtga
     6361 ccacaccgtc ttctgatgga tagtaagtca ctgaatttag gccattatca atgaaaggag
     6421 ctagtgtttc catgacttgg tgagtcagaa ctgttccttt ttcaacgatg atctcgcctg
     6481 tttctggatc aactaatgtt tcagctaatg tcagattcaa tagacgtgtt ttcaaatcta
     6541 attttttgtt tactttgtaa cgaccaacgt ttgctaagtc gtaacgtttt ggatcgaaga
     6601 aacgagcatt cagcaagtta cgtgagctgt ctgctgtttt tggttcgcct ggacgcaaac
     6661 gttcgtaaac gtctttcaaa ccttcttctg ttcttgagtc gcttgcgttt ttatgcaagt
     6721 ctttttcgac tgtattgcgt aatgtttcgc tgtcgccgaa gatttcaaag atcgtatcat
     6781 cggaaccaaa tcctaacgca cgaactaata cggttaaagg aatcttacgt gtacggtcga
     6841 tacgtacata agagatgtct tttgcatcag tttccatttc tagccaagct ccacggttag
     6901 ggataacagt agaaccgaat ccttcttttc cgtttttgtc gacttttcca tggaaataga
     6961 cacctggtga acggactaac tgagaaacga ttactcgctc tgccccgttg atgatgaatg
     7021 ttccttgttc tgtcattaat gggaaatcac cgaagaatac ttcttgtgct ttgatttcgc
     7081 cagtctcgcg gtttgtcaaa cgcaatgtta catgtaatgg tgcagagtag tttgcatcat
     7141 gcgcacgagc ttctgctact gtatactttg gttctttcaa ttcataatct acaaattcca
     7201 aagatagatt gccattgaag tcatcgattg gcaaaatgtc ttcaaacatt tctctaagtc
     7261 cctcatctaa gaaccattgg taagagtctg tttgaatttc gatcaaattt ggtaattcca
     7321 acacttcact gattcttgcg aaacttctac gttcgcgatg ttttccgtat tttactacgt
     7381 gtccagccaa gctcttcacc cctctaaaat gtcattcaaa aagactaccc gatcaattgt
     7441 tacaataata tttcaaatat tatttttagg taacaacaga cattttttgc ggcttttagg
     7501 caaaaaaaaa ccaaaaatag aacattctct tgaaacctta cttcgtgagc ttctactttt
     7561 gtttccttat attaaagccg aaacggacaa tatttcgttt ctgccttttc ttcatcagat
     7621 agtttttgca acttcatata ctacacttat tttctataaa agtcaacact tcctggcgtt
     7681 tcttctgctt tttcgcaaca ttttcttaat gttttcaatt ttatgttttc aattatctga
     7741 caattcttaa ttgacagacc tttttatctc ggttatactt tagaaaattc attttgtgga
     7801 ggaacttcta tgcgaaccaa catcaaccaa atcgcaccaa cacaactgaa taacttttac
     7861 tttagctact ttagataggt ttgtattcat catgatggat acaaacgtta aacgacagtt
     7921 tgtatctatg atggctaaag aactttgtat tgcagcaaaa agccacgtag acaaaatgct
     7981 aagtggctga gcagtgaaaa tacaaagtaa aagtatcaag cattctactt tttcaattta
     8041 ttttccgact tttcaatcca tttggacatt ttgtctgaat ggattttttg tttcccaaaa
     8101 ttaaggagga aaaagaaatg aaaaaaaata taatcatcgg attaggcgct gccctgctac
     8161 tagctttagg aggttgcgca caaaaagaca attccgcaga ggcatcagat ggacaaaaaa
     8221 caattggcgt attgcaactt gtacaacata actcgttaga tgctgcctat aaaggattca
     8281 aagaaggatt agcagaagaa gggtataaag aaggcgataa tctaacaatc gattatcaaa
     8341 atgcccaaaa caatcaagac aacctgaaaa gtatgagtga gaaactcgtc aaagaagatc
     8401 ctgatttgct acttggaatc gccactccag cagcacaatc tttattaaat gaaacaacca
     8461 ctatcccgat gactgtcaca gcggtcacag acttggaaca agcccattta gtcacatcca
     8521 atgaaaaacc tggcggcaat gtgactggca cgacagatat ggtgccaatc gaaaaacaaa
     8581 tcggcttact gttaaatatc gtgccagacg ccaaaacaat cggcatcatg tataacaacg
     8641 gtgaagcaaa ctctaagatc caagctgatt tggcagaaaa agaattgaaa aaagcgggcg
     8701 tcaaagtcaa agtactgaca gcaaattcca caaatgatgt ccaacaagtg acgaaaagtc
     8761 tagctaaaga tgtagatgga atctatattc ctactgataa cacgttcgca agtgcggcaa
     8821 gtgttgtcgg tgaagtcgca aaagaaacaa aaacacctgt cgttgctggc gcagttgatc
     8881 aagtcaaaga cggcggtcta gcaacagtag gaatcgacta cgaaagcttg ggtaaacaaa
     8941 cagggatcat ggcagcaaaa atcttagacg gcaagaatcc aagtgaactt cctgtcgaaa
     9001 cagcgaatga tttggaactg tatgtcaata aagacatggc caaagcatta ggcatcaatc
     9061 cagacagcat caaagaagct gaataaaaca caggaggatt ctcatgacaa atttgctctc
     9121 tcttttctta tcatctgcat cgcaaggggt cttatgggcc ctacttgcga ttggtgtata
     9181 cgtcactttc cgtatcttgg acattgccga cttgactgct gaaggaagct ttcctttagg
     9241 tgcagggatc gcggcagtaa gtattacaaa tggctatcat ccattgacag cttgtcttct
     9301 aggcttttta gggggtgcgg cagcagggct tgtttccgga ctgcttcaca caaaattgaa
     9361 aattcccgcc cttcttgcag ggatcatcac catgactggt ttatattctg tcacatcccg
     9421 tgtgatgggt gcgccgaaca tctctttatt gggtcagcca acgatctttc attgggtcga
     9481 gtcattcggc ataacaaaag acaacgctgt actgatcgtc ggtctgcttt ttgctttgat
     9541 cgttgtatgt ttacttgttt tgttcttacg tacagaaaca ggacttgcta ttcgtgcaac
     9601 tggcgataat ctggcaatga gcgaagcaaa cgggatcaac acagataata tgaagatcat
     9661 cggttatatg atttctaatg gatgcattgc tctttctggc tccttgcttg cgcaaaacaa
     9721 cggctttgct gatttaaatt ctggtattgg aacgatcgta attggacttg cttctattat
     9781 catcgcagaa gttttgttac gtaaccagcc actatttctc cgtctcttga ctgtcgtttt
     9841 aggtgcggtc atttatcgtt ttattttagc gttagtcttc gaactgaatg ttgaaccaag
     9901 tgattcgaaa cttgcttctg ctttcgtgct agtgatctgt ctttctttcc cgcagatcca
     9961 gcaaaaattc catttacctc aaaaaaagaa aggcggtagt gtcaaatgaa tgacgtctta
    10021 acattggaaa atctccatca tacctttgaa aaaggaacga tcaacgaaaa tcatgtcctg
    10081 aaaggcatta atctttcctt agatcccggc gacttcgtga cgatcatcgg tggaaatggg
    10141 gctggtaaat ctactttgct gaacagcatc gccggtacat tttctgtcga tcagggtcaa
    10201 attttattga atggaaaaaa tatcacgaaa aaatctgttg tcgaacgttc gaaatccatc
    10261 agtcgcgtat tccaagatcc taaactaggg acagccgttc gtttaacggt agaagaaaat
    10321 cttgctcttg ctatgaaacg aggaaaaaaa cgcggcttct tccgtggtgt caaaccacaa
    10381 gaccgaacat ttttcaaaga ccagctggtt cggctaaatt tggggttgga aaatcgttta
    10441 tcctcagaaa tcggtttgct gtctggagga caacgtcaag ctattacgtt attgatggcc
    10501 acattacagc gtccagaact gatcttatta gatgaacaca ctgcagcgct tgaccctgct
    10561 acttccaaaa cggtgatgga attgacagaa aagctgatca ctgagcagaa tctcactgct
    10621 tttatggtca ctcatgacat ggaagacgcg atccgctatg ggagtcgact gatcatgctg
    10681 catcaaggaa ggatcgtcgt agatatccag caagaggaaa aacagcagct cacagtgccc
    10741 caattattag cgttgttcaa acaaaacagc ggcacggcat taaaagacga tcaagtactt
    10801 ttatcttcat aatcagaaag aggatgggac aaaaaatgaa cgcccaccct cttctttttt
    10861 ctctttcctt ctttcgtttt tgctttatgt atcaaccgtt gtttcttcga aaactatttt
    10921 gttctctcct tcttcctgat agaatggatg ggaaaggagc ttgatgccat gacaacgaaa
    10981 gacaaggtac ttcaattatt gaaaaagaca ccagattttc tttccggaga aaagttggca
    11041 cagcaactgg aagtttcccg gacaagtatt tggaaagcca tcaaagaatt ggaaaaggca
    11101 ggctatcgtt ttgagcacgg gcctacaggg tatcgttacc tgccctctga cgtactagat
    11161 gcaaaagaaa tccagcaaga gctacggtcg tttattcctg atttgaaagt acaaacgatg
    11221 ttgacttctg aatctacgat gaaagatgtc aaactggcag cagctcaagg agattctgtt
    11281 tcgaagttat ttgttgctga tacacaagaa caagctcgtg gacgttttgg acggcctttt
    11341 ttcgctgaac ctggacgagg aatctacatg agtctcttgc tccatccaga caaacggttt
    11401 gatgaattgc ctcaatatac gatcatcgca gccagtgcct gtgtgaaagc cattgaatct
    11461 gtaaccggtc gttctgcttc gatcaaatgg gtcaatgata tctacatgga tggaaaaaaa
    11521 gtctgtggga ttttatctga agcagtcagt gatatggaaa gcggcaggat cagtcatatc
    11581 atcattggga tcgggcttaa tttttctgtt cctcaaaatc attttccagc tgatctccaa
    11641 gaaaaagcca tctctgtctt tcccgacgga caagctagtg tcacaaggaa tcagctaatc
    11701 agcaaaatct ggcaagaatt gttcacttat ctttctcacc cagaaaaagc gttggacttc
    11761 tataaagaaa aatcattcgt attgggaaaa accgtgtcgt tcaatcaaaa aggaacgact
    11821 tatgtcggtc ttgcaaaaga aatcggtgat catggcgaac tgatcgtcca aacaaatgaa
    11881 cagaagatga gtttgtcttc tggcgaaatc agtctcacat ctatccgtac gcaataatta
    11941 tcagatttca caaaaggaca cctgatctca tacagtgtcc ttttttctga attctcttca
    12001 aaagactctc cttattctat cagctgacag tttctctatc ctctagaaaa aggtattcta
    12061 aaaatatcta taaagcatgg tacactttct ttaaatgaat caatgcaaaa aacaagagag
    12121 tcatcagttt acacgatcaa aagagatagc aggccgcttc ctttttcaat cttatagata
    12181 gaccatgggt aacgataaaa acaaaaaaga acttgcgact tattttgccg taagttcttt
    12241 tttagctagt gccttaatct cttaatccca acaaacgtct cgcatagatc acctgaccag
    12301 agtgcatagc agcatcatca ataatagaaa cgagacgcat tcctcgtgtg actggtggtg
    12361 tccagttctc gtcaattact tcatctagct cggaaggttc cagccttctt aagtaagaaa
    12421 tagcaaaatc agcagctcct cgcaagtatc ctagcagatc ttctatttga ttagcttgga
    12481 tctgctttgc ttgttccaga ctatgcttcc aatcttgttc gttatctgct atcgtcatcg
    12541 gaaaccggct ttcccagtct tgactatgcc aaattggaga agttcctgct aaatcagcaa
    12601 tctggaaatc taattctcga gcggtatgcc aagccagcca agtcattgat ttgatctgcg
    12661 gggctctatc ttccactgga aaacgattgg cctcctcaat agagacgcct tcaaacaaac
    12721 gttcaaaccg atcgtatgcc cgatccacac tctcgcatag catatctaaa taatccattt
    12781 attttcctcc tttttattta tcctacttac tttttcctaa ttctaggata cctacttata
    12841 tgttactaca cacccttatt ttttacactt taacagtcac catcatcaat agtttggaga
    12901 ttgaaagaaa aagatagtgt cgaactatca attgaacaag aagcaacaat atgaacgttt
    12961 cattaatatt ctttaaataa acaatgattt ttcaaacgaa cagtttaaga ctaggagaaa
    13021 aagagtataa taggaaaatg tttgaaagga aaggaagggg aaaaatgaaa aaaagggcaa
    13081 gtttactagt cctagttgct ttgttgttca atatcttttc gtatggtgtg gccgtttcag
    13141 cggaaacata cattcctaaa gaccctggga atatttataa tgatctaact ggtaactatg
    13201 gcttgttagg aattgctagt caattccacg tatttgctaa aaataagaca actgtgaatg
    13261 cacatacaga cggaaatata gcaacacatg aacttgatgc aaaaaataat tttggtacag
    13321 agcttcatga aggtttattg aaccaagaaa taaattatat acaaaaaact gattctttcg
    13381 ctaattcttc aggcatacct acaggtagca caagaatgaa taaatttgtc gttggcagta
    13441 acgtggatgt agcacttcaa gatggtcatc ctacagtcaa tggatccagg cttgatcact
    13501 taactccaga tgatttttat aaagatcgtg ctgggcatga atatattgat ttcgagcagg
    13561 aatttgctaa attgaatgta gcagcaaatg atcttgcaac gatcactcca gctaaaacat
    13621 atactgctgc agattttcca gacatgaaca atcggacaat cgatttaact gatttatcag
    13681 ataccgggtt tttattggta aatatcgatg cagaagtgtt aacgatgaat acgccacttc
    13741 aaatcattaa tccaaatgat caagtagttg tatttaatgt catcaacagt tcttctgcat
    13801 tgaacgtaca gtcaccaatc aaatacaatg atcgttcaaa tcatgaaaca gaagattttt
    13861 cggatgcgaa tatctcttgg aattttggaa atgagatgac tgatttgaca atcagtgctc
    13921 cttttcaagg aacaatcctt gcgcctaatg ctactatccg cattactcaa aaccaagacg
    13981 gaacgattat aggaacaaat gtgattttag atgcagctac caatcgttgg gatcctaacg
    14041 aaatatttat cagcgacaat ggtacagata cgacagacac aagcgacagt acagatacat
    14101 ctaccacaag tgatagctca gattcatcaa cttcaagcga cagtacagat actacctcta
    14161 ccacaagtga tagcacggat acatcagctt caagcgacag tacagatact acctctacca
    14221 caagtgatag cacggacaca tcagcttcaa gtgacagtac agatactacc tctaccacaa
    14281 gtgatagcac ggacacgtca gcttcaagcg acagtacgga tacatctacc acaacaagtg
    14341 atagcacgga cacgtcagct tcaagtgaca gtacagatac tacctctacc acaagtgata
    14401 gctcagattc atctaccact acaagtgata gcacggacac gtcagcttca agtgacagta
    14461 cagatacatc ctctaccaca agtgatagct cagattcatc aacttcaagc gatagtacag
    14521 acacgtcgtc taccacaagc gatacacgtc atgcaagtgt ctccttctca aaaacaagtt
    14581 cggataacag gacgaacttt aacttaacta ataaaacaag caatgacaat ggaaacaaat
    14641 caaaaagagc acttcctaaa actggaagtc aatcgaataa ttggataaca ctcgcaggcg
    14701 ttatattact tgtaatcggt ttaagaatca cttttatgag ttataagaaa tcgaaaaggt
    14761 aaaaaaatat tcaagataaa aaagagcaac gtcgctaacg gacgttgctc tttatttttg
    14821 ctttttatca taaatacaag aactacaatt caatttgtca aaaaacacgt agatttcctt
    14881 ctgagaaatt tatttacgta tcgaaccttt ccctattcag tctttgcgat ccaaaatcag
    14941 ttgggtaagg gaaaagagat tctcttttgt tcgaagagag gtggcaggta atttctttat
    15001 ttccttcaaa gccttttctg tgtaagaggc cgctaacttc ctagcttctt ccacgcctcc
    15061 tgtatgttca acgattttgc gtacggcgtc gacatcttct tctgtcattg ccgctttctt
    15121 ctctaaataa ggtagtagct ttggtttgtt tttttgcaaa gagtagatca acggtaaaga
    15181 atagacccct tgacgcatgt cttctagtac aggtttgccg atttcctggc tctcttttgt
    15241 ataatctaaa atatcatcga taatctgaaa ggccatcccg atagaaagtc cgatatctcc
    15301 tgcttttttt gcgaagcgct cgcttgttcc actttcaaaa gcgccaacag aacaacttaa
    15361 ttggaacagt tcagctgtct tacctgaaat attttccaaa tattctttta cagaaagttc
    15421 ataattatag cgatcatcca tctgccctaa ttcgccattc aatacttttt ccatactgcg
    15481 agaattcaat tggagacttt tcaaggaagt ggagtaatca gacaatagtt taaaacagca
    15541 gacaaataaa tagtctcctg catagacaga aacgacatta ccaaactgac tacggatatt
    15601 aggctgacca cgtcgcagat ccgcttcatc aacgatatca tcatggatca gtgtggccgt
    15661 atggagcatt tcgatagaag ctgccaaagc gatggctttg tctcgatctt gctctggtcc
    15721 aaattgtgag aacaatagct gataggcagg acgcaacagc tttccgccgg catggatcgt
    15781 ttctttgatt gcttgttcga caggtttgtt tttcaggcgg acagtttctt ccatccgttt
    15841 tagtgtttct gtcaattctt tacttaaagc aggatagttt tcccacattg gatgtagctt
    15901 cataaaaaaa ctccttgtgt gacgattatt ttttggtaaa cattgggctc catttttgtt
    15961 tggttccctg ctcataatct ttttggaatc gttgaagtgt ctgcacatgt cgtaaaagat
    16021 aattcgctgc gatcccgatt gcaatccctg ataaaatccc taaaactgaa aggactggca
    16081 agtacaacat gactgtccat gattgtgcaa tgaaagaagc catcaaaagc tgtccgacat
    16141 tatgcatgaa accgccggcc gcactaattc cgatgatact gacacgtttt ggtcctaatt
    16201 gcttgaccaa taacattcca aaataactaa gcaaagcacc actcatacta taaaggaatg
    16261 tggaaatcgt tccgcctagc aaagtagtca ggaatagtcg tagccaaagt agtaagaagc
    16321 tgtctcgttt tttcatggta aaaatggcaa cgatcgtgat tagattggct aagcctagtt
    16381 ttgcaccagg cgcaaaagaa aaaggataag ggatcatatt ttccaataaa ccaatgatca
    16441 ctccttgtgc aacaagtagc gaaatataaa tcattttttg taatttactc atggtgtgtg
    16501 aaggtctaat aaatcagact gtcttcgtca cctccatctg ttgaacggac ttcgatcact
    16561 aatttatgtg gcaaacagac gatggtttcg ccatttttcg ttgcccagcc tcgacgtacg
    16621 cagatctggt catcgcaatc tgcttctttt atccgtactc gatcgccatc tatctcgatc
    16681 aagttataat ctccgtgttc atctttgtaa gtatatgtgt tgctctcttc tccagccatc
    16741 aaagggaatg ttttgatttc tgtgccatcc acacgcagta ccgcttcttt ttctgctgtt
    16801 gcggtgtttt gctgaagacc aaaaatcatg actggtaaaa aagaaagaac agtcaaaagc
    16861 aaaataataa aaacatccca aggtttgagc agactttttt cagcaaattc tttaaggctc
    16921 atttttgttc tcctttttcc agattaactc acccaatttt agcataaaaa caagaggttg
    16981 tgacacctgt gtcttgcttt gagtaataag aacgaagaat agaaaacagc tttccatgtt
    17041 ttctaattct ttgggcttat taccgagaag cagcaggtgg aacaccgttt ataacaagag
    17101 gttgtgacag aagtgggcaa cttcaagaaa taagaaggaa tttacgaaaa ttacttttca
    17161 agtttttgtg aaatttcggc ttatttttcg aagaagctac ttctggaaca ccgtttataa
    17221 caagaggttg taacagaggt tgtgacacct gtgtcttgct catggaggct tatctcgggc
    17281 atcttattcc tttaatttta cataaaaagg aggctgtgac ggtttgtctc agcccctttc
    17341 tattgaaatc ttgcattcaa ataacgttct ttatctattt atttcttgcc gtactgggaa
    17401 cttggtctac cgtaccacca attacctagt gtacgttgta gccatggaat tacccagcga
    17461 tccaacccaa tcgcacgtcc ggaaccgttc atcaatgcga aagcaacaaa aatgaaccaa
    17521 atgtttaccc agtaaaacat gcctgataag cagaacgtga tcaccaatac aatcgttgtc
    17581 gcactgcata gccatgtgaa taatccagca atcaatgcta atgccaaggc aatttcaaag
    17641 aataccatga atttttggaa gaacattgct acatcattgt ttggcatgat cacttgcatg
    17701 atctttgtga accagtctgg tgacttctca atcacagcca ttggttcttc accgtatgca
    17761 taactcaaac caaaatgtgc agcttgagtc gctgcttctc cggcacttgc ccctgctccg
    17821 ctggcagctg tggttgcatc accagcagca gaagcaccac tggcaacatc tgttacattg
    17881 tattcccatg tccaagggaa cacactgttt ccagtgaacc atgatccttc accaaaccaa
    17941 gtacttggtt tgaacacttc accattccca atgatttttt tggaagcttc aacgaaccaa
    18001 actaaaccat agaaaatacg aagtggcaca ctccataaga cattgccgta acgagaagaa
    18061 tgtcctcgag tcacgttgcg atcatctttg atatggaaaa actcatgcat taaatattgg
    18121 aacatataat aaccagaacg aatatcaaag aagtatttca aattcacgat atgtttcatt
    18181 acgatagcta aaaatccgct taaatggatc ttatcaaata ggttagctac cccccatttg
    18241 gcaccaatag aaaccataaa tccttgatag tttcctttaa atttatgctt ttctccgcct
    18301 ttgatcgaag ccacgatatt cgctgcggct gtgtgtcctg tttgttcagc agcttgaacg
    18361 atctgcggtg tcggtgttcc tgggaattct tcataaaaga ctaaatcacc aatgatatag
    18421 atgtttttat cttcgtagcc ttttgcctgc atatattcat tggcgatcaa ccgctgtccg
    18481 cgtgctgatt ctaatccaaa gtcagcagcg tcagaagttc ctttgacacc agctgtccaa
    18541 atcagtgtgt gagtcggaat gttgcgtccg tctttcaatt tgatatgatc agcagccact
    18601 tctacgattg gtgcattcaa taataattcc acgttgtgct tacgcaaata gcgttcagct
    18661 tttgcagcat catttcgatc caacatattc aagatcgtcg gcattgcctc tacgaccatc
    18721 agtgtgattt cgtttggatc taatttataa tctttggcta ggcgattttt ccagtcgatc
    18781 agttccccaa tcatttcaat accggtaaat ccagaaccac agacaacgaa agtcagcatg
    18841 gctttacgca gttcatcatc tggttccaat gcagcttttg ctactgtctt ctcaatatgt
    18901 tcccgaatcc ttacagaatc ttcaaatgac caaagggtga atccgtgtgc tttgacacca
    18961 ggtgtaccaa agtcattcgg ctctccgccc attccaagga tcagctgatc aaaaggatag
    19021 gaacctaatt tggtcttgac gatttttcgt tctttatcga taccgattac agtgtctgtg
    19081 acaagttgta cattcttttg acgagcaaac aaatgctgca gatcgtattg gattgcttct
    19141 ggttctacac gtccgccagc tacttcatgc aactcggtca tcatagtatg gtacgaatga
    19201 cgatcgatca gagtaattgc tacatcttct tttttcagtt tctttgccaa gtattttgta
    19261 gctgaaacac cggcatatcc tgctcctaca acgacaatat tttgctttgc cattgatcat
    19321 ccgctcctta tagactatct atataatgaa tatatgataa ttcttttagt ttgatactta
    19381 ttacacaatc tccatatatt atatagatgt tctgttcttt tgtctaactc cttttggatt
    19441 tttttcaaat tttaaaataa agcgtttttt cacgaaattt gctgaaagaa aacgtttgaa
    19501 atattacatg ggttatttat caaaaatagt tgacttatag gctaaaaaga ttagaatgta
    19561 taatgaatca caaagaaaaa ttgtggacta gaaatggaat ggtggggtat taaaatgaag
    19621 aaaaaacgtt ttgtaactgg atttgccgta ttagcatttt cagctctagt gttaggcgct
    19681 tgcggcgcag atgacaacgg aagctcaaac tcttcttctg aatcatctac agcacaatct
    19741 tcgactgcaa aaagcacaac agaatcatct gcaaaagttg tagctggcgg agatttgcaa
    19801 gacggcacat ataaattaga agaaaaaaat tattcaaatg gttaccgtgc agtctttgaa
    19861 atggttgtaa aagacggcaa aatcactgaa tcaaaatatg ataacgtcaa tgaaaacggc
    19921 gaatcaaaaa caaaagatgc agaatacaac aaaaacatgg aagcaaaatc tggcacaaac
    19981 ccagaaaaat acattcctga gttgaatgac caattcttaa aagcacaaag cgcaagcggt
    20041 gtggaagtcg taactggagc tactcactca tctgaaagct tccaaaacta cgcacaacaa
    20101 ttgatccaag ctgctcaagc tggtaacaca gatacaatcg aaatcgacaa tggtgctgat
    20161 ttgaaagacg gcacttacaa gcttgaagaa aagaactact ctaacggcta ccgtgtgcaa
    20221 ttcgaaatga cagttgctgg cggcaaagta actgaatcaa actttgatta tatcgacaaa
    20281 gacggtaaat caaaacaaga tgatacagaa tataatgaaa atatgaaagc aaaaagcggt
    20341 acagaaccaa aaacttacat ccctactctg aacgacgaat tcgtcaaagc aatgggcgaa
    20401 gaagatggct cacctgctaa tgtagaagtt gttacaggtg ctacacacag ctcacattca
    20461 ttcatcatgt acgcacaaca attagtgaat gcagctgaaa aaggcgacac tcaaacaatc
    20521 gaagtagata atatcgtaac agaaaaataa tcacataatc atactaataa aagttggagg
    20581 gtgggacgat agccagatta ggcagtcgtc tcacctttca aaatgaagag aggaaaaaga
    20641 tgcggaaaaa actactattt tccttaatca cactgggcat ctcttttatg gtgctaactg
    20701 gctgcagcaa ctcagcaaat aaaacaacca ctgaaagttc agcagctacc aagatattga
    20761 aagatccata ttctgatgaa cagttcttgt tagggactta cgttcgtatc cgtgtgtatg
    20821 atgaaggcaa agaatcagca ttgaaacctg ccttcgatcg agtaaaagaa cttggtgata
    20881 aaatcacgat caatcaaaaa ggttctgaga tcgatgaagt gaatgagcaa gctgggatca
    20941 aaccagtaaa agtttctgat gacgtctaca cgttagtcaa gcgggcctac gaatatagcc
    21001 aagattctca aggcggattc gatatggcga ttggtgcaat cacacaatta tggcgaatcg
    21061 gttttgatga cgccagaaaa ccttcccaag aagaaatcga tcaggcattg aaattagtgg
    21121 attatcataa gatcgaacta aatgacaaag aaaaaactgt ttatctaaaa gaaaaaggaa
    21181 tgatcatcga tttaggtgca atcgccaaag gttacattac ggacgaagta gtgaaagtct
    21241 tgaaaaaaca aggagtgacc actgccatcg ttgacttggg cggtaatgtc tatgtcttag
    21301 gccacagccc aagaggcgaa aaccaagact ggacagtcgg catccaagat ccgaacatgg
    21361 ctcgcggatc tgttttaggt tctattaaag aacggaacaa aacattagtt acctctggaa
    21421 tttacgagcg ttatttagaa gtagatggca aaaaatacca tcatttgttt gatccaaaaa
    21481 cgggttatcc gttcgacaat gatatcgcaa gtgtcacgat cataacagat aaatcaattg
    21541 atggtgacgg gttgtctaca gcagtctttt caatgggtgt gaaaaaagga ctggaatacg
    21601 tcgaaagcga attgaataac gggacggaag cgatcttcgt gacaaaagac gataaagtat
    21661 atgtgaccga tccaatcaaa gacaccttca aattatcgga ggactcccat tacacgatgg
    21721 gtgaccgttc tgaactaaaa taaggagtac gaaccatgac actaaaaatc tttttagaag
    21781 tagttgaaat acgaacaaag gtggctagtg tatttccttt tgcggtaggg gtattattct
    21841 ctatcgcttt ttttcatgag atacattggc taaacacttt tttatttttt attggaatgc
    21901 tagtttttga tttagcgact accgctatca ataattacat ggattatgaa aaggctcatt
    21961 ctgaagtata taagtatgaa gaaaatgtca ttggccgcag aaatctatct cctgtattga
    22021 ttcgaaacat gattttagct atgattgcat ttgtttttgt tatcggcgtt attctaacga
    22081 tcaatacggg ttggctttta cttttgatgg gatttatctg ttgttttatt ggagtattct
    22141 atacattcgg accgattcct ttatctcgaa tgcctttagg ggaaattttc agtggggtga
    22201 ctatgggcct tggaattttt gccatggtcg tttatgtcaa tacattcggt tcagatgtct
    22261 atgatctgac agtcaacttt tcatctggac aatttgcttt ggtaggaaat ctttgggcta
    22321 tagcagcaat cgtattagct tccttaccct tggtgtttac gattgccaat atcatgttgg
    22381 ctaataattt gcgggatctt gaccgtgata ttgaaaatca tcgctataca ctagtttttt
    22441 atatcggacg tcctgcggga acagtcttat tccagctatt gatgtatgct tgctatttcg
    22501 tgattttaat ggggttgttg agcggtatct atgaatggcc gatcttggtc accttcttga
    22561 ccttgccaat tgtgaagaag catttggatc aattcaagca aacgttaccc cagcctatca
    22621 gtttcagcta ttccatcaaa aatatggtct tattcaatgc cagttatgta ttggggctat
    22681 tactaacaat cattatgcaa gccatttaac agcatgaaga ggttgtgaaa aaactgccct
    22741 gcatcaagta ataagaacag ccaaataaaa atagctcctt atatttttcg tttggttggg
    22801 cttattaccg cagatgcaag cttttgaaca ccgtttatca ggaggttgtg aaaaagtcgc
    22861 ttagtttcga gtattaagaa aaattttgtg aaaatggctt tccacatttt tgcataaatt
    22921 tggcttaata ccgagaaact ggcttttgaa caccgtttat cagaggttgt aaaatcagtg
    22981 ttttgtcctg agtattagag aaacaaatgg aaaaatagtt cctcatattt tgccgttttt
    23041 tgagctaata ccgaaggaca gctgattgaa cactatttgt tcggaaaaag tgactaacta
    23101 tgacacaatt tttttcacag tccctttttt cacttgattt gattcgtacc agcgaacttg
    23161 acgagaactt tcttggtttg gtaactatat ggtattcttt taacatcctc gtttgcttct
    23221 tctaatttat ttatacaaag tcacactttt ttaaacatct gttcttcgat acatttctat
    23281 ttcttttaaa catcgatacc aatattttga acttaagagt gcataccaaa tggattcatt
    23341 tactcttcgt cagttacgaa gataatcaaa atctccaact tccctactta tttcgttttg
    23401 agaattatcg aagcaatctt acataaataa ctaaaaaaca aaaaaccaga aaatcagtat
    23461 actgattttc tggttttaca tggtttgttc aataaaaagc tgttggaact gttaatatta
    23521 aattatcgca tcgttacgaa ttcttccgct cctgttggat ggatggctac tgtattgtca
    23581 aagtcttctt tagttgcacc catcttgata gccacggcaa aaccttgcag catctcatcg
    23641 acaccaacac caatagcatg taagccgacg attctttctt cttttccgac acagatcaat
    23701 ttcatttcgc atttttggcg ataatcattt aatgcaaagt acattggggt aaagcgtgaa
    23761 cgataaactt tcaattcatt ttcgccatat ttttccaatg cttcttcttc tgtcaaacca
    23821 attgttgcaa ttggtggatg cgtaaagacg actgtcggaa caagtttata gtcaagataa
    23881 gaatctttct ttccattaaa taaacgttct gataaacgtc taccagctgc gattgcaaca
    23941 ggagtcagat ctaatttacc gatcacatca ccaacagcaa aaatatgttc atccgttgta
    24001 ttttggtatt tatctacttt gataaaccct tttttgtcca attccacatt tgtattttcc
    24061 agacctaatt tttcggtatt cggtacacgt ccaccggcaa aaagtacaca atcaccagtt
    24121 aaggtttcac cattttcaaa tagcaccgta tattcgtcat tgtttttagt aatttcttta
    24181 gcaatatgat gtgcgtaagt ttttattcca gcttcttggt acatttggat caaattgtcc
    24241 gaaagcattt tatcaaacgt tctaagtggt cgttcttttc gatatgccca catgacttca
    24301 ctacctaaac cacgaaatac acctgaaagt tcagccgcaa tgtatccagc acctaaaacg
    24361 attgctctct taggtaactc tgttaattca aaaaatccat ttgaatcaat tgcgtattct
    24421 ccaccaggaa tggtcatttt acttgcacgg cctccagtag cgatcaagat tttaggagca
    24481 cgataggttt caccgtttac ttcgatcgtt tgactatcga taaaagtagc gtaacctttt
    24541 atagcctcga catgattgct atctaatcct ctttgataag caccgtgtag aaaatcaata
    24601 tatttttctc gtctttctac tagaccggcg aaatcaacat tttttaaatc tgcttggata
    24661 ccgtaacttg aggcatctcg ttcaattgtt tccaaaatcg tacttgcttg ccacataact
    24721 tttttaggta cacaaccgac gttgacacat gttccgccca attcattcgc ttcaatcagc
    24781 aaaacttttg cgccatgcat ccctgctctg tttgctgaag caataccgcc agagccgcca
    24841 ccaattacga tgtaatcata tatttgcatt ttgttcctcc ttattgaaga gatcaatcaa
    24901 aacctttatt taacgatcct ttttctacag aaaacaagtg taacactttt cttgaatttt
    24961 gtatgcgaag atgcttaaaa cagggatata tcagcttttt ccttatttac gttttcggat
    25021 catatctcca ggtttcaccg gctgtgcgac tggcatagtt aaaatcatca ttggatttgg
    25081 tgctcggtca atggattcgc cttcttcatt atgcataact tcaacggttt gactgaaatg
    25141 actgaatcct ggaccataaa attcgatttc atctcctaca gaaaacaagt ttctctgacg
    25201 tatcgtagca atctgtgttg cctcatcata agataatact tcaccgacaa atttatatac
    25261 tgggatttta cgacgttcac cgaataattg ttcgttttca gttggtgtat tgtagtaaaa
    25321 acctgtagct aattctcgtt gtgctacttt ccataactcg tcgatccatt cttgcttgca
    25381 gacatagttt tcaggatctt ccatataact gtctacagcc gctttataga catttgacac
    25441 cgtagataca taatggatcg atttcattct tccttcgatc ttgaagctgt ctacgccgtt
    25501 ttcaatcaat tctggaatat gttcgatcat tgacatatcc actgcactca tcgagaattc
    25561 ttcttccact tcgcctgtat cagttaaact gtttcgttct tgaccaaaag gcatatcgaa
    25621 caatccatac ttccagcgac aagattgaga acatccgcca cggtttgcat cccgcatcga
    25681 catatggttg gacaatgtgc atcgaccaga ataagagata cacatggcac catggataaa
    25741 tgcttcgatt tcggtatccg tatttttacg aatctctgcc acttcctcca ttgaaacttc
    25801 acgagctaaa acgacacgtt ccaacccttc ttctttccag aattccaatg tctcaaaatt
    25861 agttgctgaa gcttgagtgg ataaatggat cggcagacct ggggcttctg tcgcacaaat
    25921 ttcgatcaaa gctggatcag aaacaatcac tgcagaaata ccgacatcac gcaaactgcg
    25981 gaaaaattcc cctgctccat cttcatttcc ttcatgggtg accatattag cagcaacgta
    26041 taccttcgca tcatgttctt ttgcaaaagc aactccttca gccatttctt cataagtaaa
    26101 attacctgca cggcttctta aaccatatgc attcccgcca atatatactg catctgctcc
    26161 ataatggatc gcggttttta acttttccag tgttcctgct ggcgctagga tttctggtcg
    26221 tttcaatttt ctttttactg tcatttcttt catcatactc cttatttgat agcagaagga
    26281 tcaatataaa agaatcctgt atctaattca cggttttcag gatgcaattt actgatttcg
    26341 ctagtcattt tttccgcttt ttcttgatcc cagctacctt ctaaaatttg tttttttgct
    26401 tcggcgaata gtcgagtgat gtttacgaat ttttcgcctg gagtaaataa tccgtccaat
    26461 ttccatgtac agtaatgatg ctgataaagt tcattcaatt cattcgagag attcagatca
    26521 ttgctggcaa aaatatgtgt gccatgacta tcttcataaa tagaataatg tgtctcttct
    26581 tttttaggtt ccgagataaa aagacctctt tcacgatctt tttgttcgtc ttgtttcgta
    26641 tagttatagt aattctgtag cagtggacgt ttggattgat ggatgcatgt agcaccatac
    26701 acaagggttt ctacaggaat atcgagtttt tcttccatcg ccttcatctc ttcaaaagga
    26761 acttcacgag caagtactgc tccaactgcg ccttttttcg cccagaaatt gatttgacgt
    26821 gcgctcgtta ctaatgtttc agcatcataa atatacggta tacgcaattc aggatttttt
    26881 ttcatcgtat aaataatacc tgtatcacca actgtgatca catctacgtt tatttctttt
    26941 aaaaaagcca aatattcagg tacatttttc attttttcag gatgaatgat cccatttaca
    27001 gcaatattcg cttttttacc atacttgtgt gctaattcta ccaattgtcg ctgttcttct
    27061 cgtgtaaatg aagcaggcag acgcaatcca aattgctctt caccgaaata tagtgtatct
    27121 gcacctgcag caagcaactg ttctgcttgt tcaatagttt ctactgtggt tatgagttcg
    27181 atcataattt tctcctccta caacttcata atagtagcat agctctaaaa actttccaat
    27241 acttcttcta tttaaagtcg gatttttgaa aattatttca caaaaaatca aaataaagtt
    27301 cgatatattc tgtccaaata taaaaagaga ttgtgacaaa aatcttgtca caacctctta
    27361 atcaagtctt actattataa aaattcagct acacaggcca agtaactata gggaacctac
    27421 tgtttccttt ttaggtccgc gaacattcaa tgtgatctta ccttttgaag cacctactgt
    27481 tacgtggtca cctaaacgaa tttctccgcc aagcaaagcc tcgctcaatc gatcttcaat
    27541 ttctttttga agtgcgcgac ggattggacg tgcaccatat tcaggatcaa atccagcttt
    27601 cccgatcaca tcgattgcag atggtgtgat tttcacttga atatcttgtt ctttcaatcg
    27661 tttgataatc gctttgctca tgatttggac gattgtatgg atttcatctt tactcaatga
    27721 atggaagacg acagtctcat cgattcgatt caagaattca ggtcggaaag ctttctttaa
    27781 ctcttctaag atacgttttt gcatggcttt gtgatcttta gtaacatctt ggacattgaa
    27841 tccgacattt ttttcttctc gaatttgtgt cgctccgata tttgaagtca taatcatgat
    27901 tgtatttcta aagtccactt ttctaccttt agaatctgtt aaatgaccat catccaatac
    27961 ttgcagaagt aaattgaaaa cgtctggatg tgctttctcc acttcatcta agagaatcac
    28021 tgaatatggt ttttgacgaa ttttttctgt caactgtcca ccttcatcat accctacgta
    28081 tcctggagga gacccgatta atcggcttgt actgtatttt tccataaatt ctgacatatc
    28141 aacacggatc agggcatctt cacttccaaa catgacttct gaaagtgctt tggccaattc
    28201 tgtttttccg acaccagttg gtccaaggaa catgaatgaa ccaattggac gatcaggatc
    28261 tttcaatccg cttcgtgcac ggcggatcgc acgtgaaact gctttgacag cctcatcttg
    28321 accaacgaca cgttcatgca gaagtccttc cagttctaac aagcgttcgc tttctttttt
    28381 ctccaactgc tgtagaggga taccagtcca ctccgataca actgtagcaa catcttcttc
    28441 tgttacacga tcagaataac cttgctcctg ttttgcttca attgcagaaa ctttttgcag
    28501 ctttttacgt agtgcttttt cttgtctgcg taattgagca gcattttcaa agtcttgttt
    28561 ttggatcgct gcttcctttt cttgtactag ttcatcgatt tctagtttga tcacagttga
    28621 ttttgttaag tgatcggttt gatccaaacg gactttcgct gctgattcat cgatcaaatc
    28681 aattgcttta tcgggtagtt gacgagaagt gatataacga acagaaagat tgactgctgc
    28741 tcgtacagct tcatctgtga tctccactcc atggtgctct tcatatcttg tacgtaatcc
    28801 ttgaagaatc acttctgctt cttcaggagt tggctcatct acttgaatgc gagcaaaacg
    28861 tcgctctaat gcagaatctt tttcgatata tttttgatat tcatctaggg tcgttgctcc
    28921 gatcgtttgt aattctcctc gagctaacgc cggtttcaag atattcgaag catcaattgc
    28981 tccttctgct ccacctgcac caattaaggt atgcaattca tcaatgaata agattacttg
    29041 accatcatta tagatttcgt cgatgacctt tttcattcga tcttcaaatt caccgcgata
    29101 tttcgtacca gcaaccaaag atcccatatc aagcatcatc aggcgctttt cttgcatgtc
    29161 ttctggcact tcacctaaaa tgattttttg agctaaccct tcagcaatgg ctgttttgcc
    29221 tacaccaggt tcacccacca gtacagggtt attctttgtc cgtcggctaa gaatctggat
    29281 aagccgtttc acttctctcg aacgaccaac aactgggtcc agcttgtttt cttttgctaa
    29341 tttcgtcaaa tcacgtgcta atgaatctag cgtaggtgtt ccttgcggtg tttgccgttt
    29401 atcttgtaca tttacatttc tacgacgatt cattcctttt ccagcagaat caccagctag
    29461 ccccattttt tgtttcagaa cttgacgggc ttttgaaagg ctgataccta agttgatcat
    29521 gattcgagta gccatgatac tttcatcttt taataagctc atcaaaatat gttctgttcc
    29581 aactttttga gaaccagttt tcttcacttc gctgctagct aaagcaaaaa cttgtttcat
    29641 tcttggtgaa tatggaagaa agactccttt agggtaagaa cggataccac cataaccaat
    29701 cagatgttca atttcttcat aaatttccgt ttcattcaaa tccatttcac gtaatacttt
    29761 tccagcaatt ccattttgct cgaccactaa ggctagtaaa acatgttctg aactaactga
    29821 ttgatgtttc aaccgttttg cttcttcttg tgcaatttct aatactgctt gggctctttc
    29881 agtaaaaagt tcttccatct aatctcactt cccatcttca taacttaaac gttccagaaa
    29941 tgctcggaga atccgagcac gtgtatgatc ttcatattca ttgaaattca atgtgttttt
    30001 tgcaattgca ctcaacatca agtttccttc tttttttgta attatttggt cttcataaag
    30061 tttttgaata atagcaaaag catttttctc actgattgta tcatcaaata actgatttat
    30121 ctgctcaagt aattgttttt tatctgaaat ccttactttt gcaattcgta tataaccacc
    30181 accaccacgt ttgctttcta ctagataacc acgttggatg gtaaaacggg tattaatcac
    30241 atagttgatt tgtgaaggaa cacagttaaa gaggtctgcc atttcaatcc ttcgaatctc
    30301 gatcatttca ctattttcca gaattttctt tatatatgat tcaattaaat ccgaggtatt
    30361 ctgatgtgcc atcttattca ttccctttga ctaatattga ccttaattat aacgaatttg
    30421 ataatagaaa gaaagaagaa cgctttttgt taaataaatc ctttagaatc aacaaaaaaa
    30481 aatacggaat atactattcc gtatc
//
LOCUS       DAFLWC010000026        30492 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.026, whole genome shotgun sequence.
ACCESSION   DAFLWC010000026 DAFLWC010000000
VERSION     DAFLWC010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30492
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.026"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(220..972)
                     /gene="xth"
                     /locus_tag="L1V17_001088"
     CDS             complement(220..972)
                     /gene="xth"
                     /locus_tag="L1V17_001088"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBN1235871.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            1085..2005
                     /locus_tag="L1V17_001089"
     CDS             1085..2005
                     /locus_tag="L1V17_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1235872.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            2078..3013
                     /gene="murB"
                     /locus_tag="L1V17_001090"
     CDS             2078..3013
                     /gene="murB"
                     /locus_tag="L1V17_001090"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBN1235873.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            3311..4789
                     /locus_tag="L1V17_001091"
     CDS             3311..4789
                     /locus_tag="L1V17_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1235874.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            5066..7126
                     /locus_tag="L1V17_001092"
     CDS             5066..7126
                     /locus_tag="L1V17_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HBN1235875.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            7209..7778
                     /locus_tag="L1V17_001093"
     CDS             7209..7778
                     /locus_tag="L1V17_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1235876.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKSDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(7953..8759)
                     /locus_tag="L1V17_001094"
     CDS             complement(7953..8759)
                     /locus_tag="L1V17_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235877.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            8897..10411
                     /locus_tag="L1V17_001095"
     CDS             8897..10411
                     /locus_tag="L1V17_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HBN1235878.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(10814..11797)
                     /locus_tag="L1V17_001096"
     CDS             complement(10814..11797)
                     /locus_tag="L1V17_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HBN1235879.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(11802..12449)
                     /locus_tag="L1V17_001097"
     CDS             complement(11802..12449)
                     /locus_tag="L1V17_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1235880.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(12534..13166)
                     /locus_tag="L1V17_001098"
     CDS             complement(12534..13166)
                     /locus_tag="L1V17_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBN1235881.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(13182..13733)
                     /gene="coaC"
                     /locus_tag="L1V17_001099"
     CDS             complement(13182..13733)
                     /gene="coaC"
                     /locus_tag="L1V17_001099"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HBN1235882.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(13730..14467)
                     /locus_tag="L1V17_001100"
     CDS             complement(13730..14467)
                     /locus_tag="L1V17_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HBN1235883.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(14464..15453)
                     /locus_tag="L1V17_001101"
     CDS             complement(14464..15453)
                     /locus_tag="L1V17_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBN1235884.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            15711..16253
                     /locus_tag="L1V17_001102"
     CDS             15711..16253
                     /locus_tag="L1V17_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1235885.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            16270..17355
                     /locus_tag="L1V17_001103"
     CDS             16270..17355
                     /locus_tag="L1V17_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1235886.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            17367..18173
                     /locus_tag="L1V17_001104"
     CDS             17367..18173
                     /locus_tag="L1V17_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1235887.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            18174..19001
                     /locus_tag="L1V17_001105"
     CDS             18174..19001
                     /locus_tag="L1V17_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1235888.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            18998..20071
                     /locus_tag="L1V17_001106"
     CDS             18998..20071
                     /locus_tag="L1V17_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1235889.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            20499..23195
                     /locus_tag="L1V17_001107"
     CDS             20499..23195
                     /locus_tag="L1V17_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBN1235890.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            23272..23760
                     /locus_tag="L1V17_001108"
     CDS             23272..23760
                     /locus_tag="L1V17_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1235891.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            23772..24266
                     /locus_tag="L1V17_001109"
     CDS             23772..24266
                     /locus_tag="L1V17_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1235892.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            24287..25096
                     /locus_tag="L1V17_001110"
     CDS             24287..25096
                     /locus_tag="L1V17_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1235893.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            25093..25914
                     /locus_tag="L1V17_001111"
     CDS             25093..25914
                     /locus_tag="L1V17_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBN1235894.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            25965..28064
                     /locus_tag="L1V17_001112"
     CDS             25965..28064
                     /locus_tag="L1V17_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HBN1235895.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            28061..29179
                     /locus_tag="L1V17_001113"
     CDS             28061..29179
                     /locus_tag="L1V17_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBN1235896.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            29218..30096
                     /locus_tag="L1V17_001114"
     CDS             29218..30096
                     /locus_tag="L1V17_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBN1235897.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            30287..30439
                     /locus_tag="L1V17_001115"
     CDS             30287..30439
                     /locus_tag="L1V17_001115"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBN1235898.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
BASE COUNT         9814 a         5238 c         6357 g         9083 t
ORIGIN      
        1 atctgcggta ataagcccaa ccaaacgaaa aatatgagga actatttttg tttggctgtt
       61 cttattactt gatgcaggac agctttttca caatctctcg ataaacagtg ttcaaaagcc
      121 agtttctcgg tattatgcca aatttatgca aaatgtggaa agccattttc acaaaatttt
      181 tcttaatact cgaaactaaa cgactttttc acaacctctt tatttcaaat ctaattctac
      241 tggacaatga tcactgccca taatgtccgt atggatcttt gcatcagcta gtcctggctc
      301 taaatctttg ctcgtcaaaa agtaatcgat ccgccaacca gcattgtttt tccttgaatt
      361 gaatcggtag ttccaccaag agtagacacc ttcctgggtt ggataaaaat aacggaatgt
      421 atcgataaac ccgttatcca acagtcgaga aagagccgct ctttcttctg gagtgaatcc
      481 agcatttttt tgattcgttt tccagttttt caaatcaatc ttttgatgag cgacatttag
      541 atccccacac acgatgactg gtttttgttt ttttagattt tccaaataat tataaaaggc
      601 ttcttcccat tctaatcggt aatctaaacg ttttaattcg ctttgagaat ttggcgtgta
      661 acaggttaca agaaagaaat cggaatattc caaagtaatc agacggcctt ctgtatcatg
      721 gatatcgata cccattccgt aagtggcatt caatgctggt tttttagcaa aaatcgctgt
      781 gccggaatag ccttttcgtt ccgcgtaatt ccaatattga taataacctg gaagatctaa
      841 atcaatttgt cctgcttgga gtttcgtttc ctgcagacag aaaaaatcgg cgtctaactc
      901 atgaaaaact tctaaaaaat ttttatttac gatggcacga agcccgttta cgttccaaga
      961 gataaatttc aataaaagca cactccttcg aattaatttc cttacctttg cgatactatt
     1021 gtacctcatt ttagaaaaaa atggtgtaag atgaaagtaa ctaaatgatc caggaggaaa
     1081 gtagatgaag attggtgtaa tcggtgtagg gaatatcgca gaaaaagcat atttaccaac
     1141 ttatgcgaaa aaacaaggaa cacttgattt ttattttgca acaagaaata aagaaacaaa
     1201 agaaagaatt caaaaagagt acgggttcca acatctatat gaaacgatcg atgagctttt
     1261 agaagaaaaa atcgaagcat gtatgatcca cgcagcaaca aaagtacatt atgaattagc
     1321 caaaaaatgt ctagaaaatg gtatccatgt ttatattgac aaaccactga gtgtccatct
     1381 aaatgaagtt cgtgaattgc aagaattagc tgataagaac caaataattt tgatgatcgg
     1441 tttcaaccgg cgctttgctc ctatggtaga agaattgaaa cgtatcccag ataagcggtt
     1501 gatccacctg caaaaaaatc gaatagcggc aaaagaaacg acagagttcg tcctttatga
     1561 tttgttttta catcttattg atacagctgt gtatttatta gatgaaccca ttttgagaac
     1621 aaaataccag ataagagaaa caaaggaatt tttggaatat gccattttac aattagaaac
     1681 acaaaatcaa acggctattt taacgatgga tttagcaagt ggcgctaata tagaaaaata
     1741 tcaagtaaca agtaaaaatg gtacttatga agtaaacgat ctgacccagc ttgtcattca
     1801 agatgctgat ggaaaaaaag tgaaagaatt tggcgactgg acaaacacgc tagtcaaacg
     1861 cgggtttgag ccaatggtag aggccttctt ttctcagatc cgtttaggta aatcggaaac
     1921 agaattgctt aaacaaaaag aagttgtaag aagtcatgaa ttatgtgagg aagtgcttaa
     1981 agatcactac cgtcatcaac tttgaacaag actggcaaga ttgtattaag cgtgatagaa
     2041 taatgaggac gtttgagaaa agaaaggaaa atcctcagtg aataaagaag aaatagttga
     2101 aagcttagcc acgattacta tattgtttga tgaaccattg atgaactata cgtttacgaa
     2161 aacaggtgga ccagctgatg tccttgcatt cccgaaaaaa caagaagaag taaagcaaat
     2221 catcgattat tgccgaatcc atgatatacc ttggatggta ttaggaaatg caagcaatct
     2281 gatcgttcaa gatggcggga ttcgcggtgt agtcatcatg ctgactgaaa tgaaacagat
     2341 tcatgtcaaa ggaacgatgg tcattgcgga agcaggtgcc tcactgattg atacgactta
     2401 tgcagctttg gcagaatcat tgactggatt tgaatttgct tgcggcatcc cgggaagtgt
     2461 cggtggagcg gtttatatga atgcaggtgc gtatggcgga gagatcaaag atgtttttgc
     2521 tgaagtggat cttttgcttg aagatggaac attgaaaact ttgacaaaag acgaaatggt
     2581 attttcttat cgtcacagta aagtccaaga attacgtgct atcgtattgg aagctcgatt
     2641 cagtttgcaa acaggggatt atgaagcaat caaagcaaga atggatgagt tgaccgaatt
     2701 gcgtcaatca aaacagccat tagaataccc ttcatgcgga agtgtcttta agcgcccagt
     2761 aggacactat acaggtcagc tgatccaaca agcaggattg caaggcctga aatggggcgg
     2821 tgcacaagtc tctgaaaaac atgctggatt catcgtcaat atcgatcatg cgacagcgac
     2881 agattatatt gaattgattg cgcacatcca agaagtaatc aaagaaaaat ttgatgtgtc
     2941 tttagaaaca gaagtgcgga tcattggaga aaaacaagca atatcagaaa caagcagaag
     3001 tttagccaat taataagtaa tggaacttaa aataagtaaa agagcaggac ggtggccgtc
     3061 ctgctctttt ttgtggttgt ttacgcaaat ggcgcaaatc ttgtacattt taacacaata
     3121 aaacaaaaaa tatagaatat ttcctcataa atttttccat tttttgcaat attctcaaaa
     3181 aaaagataaa aaatgagaat aactgatgaa aaaacaagca taatccatca taaaatcagt
     3241 ataggtgaaa agatgaactt tcatctgcat atcaagtaat tggtatgagg cattttttga
     3301 ggtgtaggat atgaagttgg attaccttat agaagaggaa gatagagaaa aactgctgct
     3361 agctagatat ttagaatttg agaaaaagaa ttatgtagtg ctgcctaagt tatatgaaac
     3421 attaggtttg tctaaattta aaacaagaaa ttatatcata gaattaaata aagaatttac
     3481 tgaattcaaa acaaagccag agatccaaat ttcagaagaa gcagagatcc atgtcgaacg
     3541 tctgaatttg acggatatca aaaatttaag aagaatctac tttcaacgat caaaaattgc
     3601 tcgactgtta acggagatcg tggattcaaa agtaacgatc gaaaaatttg cagagaatca
     3661 ttttttaagc atatcaagag cctatgtaaa aagaagagaa ttagtctctt ttcttgaaca
     3721 gcatcaaata aagttaaaga aaaacatatt agttggggaa gaaataaaca tacggaacgt
     3781 attatttggg gtatatttcg gggtctttaa tggtttttct atgccattta gagaaagcgt
     3841 catgaatgaa gcaaagagta tcgtgcaata ttttgaatat ctgttcaatt taaaactgtc
     3901 tgcaacaaaa cgaatcaaat tcaatttgct aaccactatt agtttgttga gggcctatgg
     3961 gaatcaacca atcggaaaac gtttcttttc agatgaatac tttaagagct cagaaggaat
     4021 gaagatcatc aaggatttat cacatatttc ttttcttcat atccctaaag agcagatcat
     4081 tgatgagatt tcttatatca tgttgttttt gatcacggaa gaagaatttg aattagatgg
     4141 cgcatttgga cttgcggaag ctcattttca tgatatccac atgattagtc aaaaaatgtc
     4201 agtggaattg attgatcaat taccattttc gattgaaatc tctgaagaag aaagactata
     4261 tatacgaaaa gaacttcgta tgggtatgat gcatgtcaat cgaaaaaatt ggatattcga
     4321 ctttgagatg actagcttta cgtctaaaaa gcagctacag tttttcttcg agacgtatcc
     4381 aatattcagt acagcaatcc aaaaggtcat acaagagaat aaacgctatt tcttgggaaa
     4441 agatgaacgt ttcatgattc gcttatttta tgattatctc tttttattgg tcggtatttg
     4501 tccggtatca tattttgaag caccgattca tgtctgtatt gatttttcgc aaggatctgc
     4561 ttataccgat tacattattt ctcaagtgaa aggatttaaa aattacaata ttgtgattga
     4621 gagtcgaatc acttctcgta cgaatattta tttatctgat tgtttacttg aaaaatttaa
     4681 taaagaacag ataatttgga aaaatccacc gactccagat gactgggaat attttggaaa
     4741 taccatcatc agagaaaaaa atagacattt aactgaaaaa atcagctagt atttatggat
     4801 ggcagctttg tctcacatat ttattagctg atttatgttt ttttcaaaga aaaggtaact
     4861 agatataact agatataact agatatatta cttaacaaaa ttaaaaagta cataagttat
     4921 tattccgatt ttcttgaaac aataaaaaat caaaaaaaat actctcctaa tagtccatct
     4981 tcttttgatt ttatttatat aatgaaatca tcttatgaaa attactactt catgtttaga
     5041 caagagtagg gaggactaag aataaatgtg ttcaaaaaga cgttcaaaac aactaaataa
     5101 acacgcttgt cgtttagata aggaacggtc gtgttctgaa aaacactacg ttaagtttat
     5161 gatgcgcacg atgctgatca gtttatctgt aggtgtctat atgcatgtac ccgttcaggc
     5221 aacgacacaa accatcaagg tcgtacgtac ctctgtttct gagaccactg attcccctat
     5281 cactattact catactttca ctgatgcaaa tggaaaacag ctacttcctg cattgacttc
     5341 ctataataaa gtcagttatc ctccaacgat aaaccactac tggttaattc ctaacaaaac
     5401 attatggaca tcggaaaccg gaagcagtgt gccgctttct atcttttccg atatgactga
     5461 tcctacaaaa ggtgatcagt taaaacagat cactgatatt ttgaatcatg ctttgacaga
     5521 tataaaggac ggtggaagcg cacaagtttc ttatgtatat gaaaaagatt attcacagtt
     5581 tgaaagaaag aaaatcgatg ttctggcagg gacaaaagtt tcgatatctg atctggtaga
     5641 aaggctgaag aacgcagatg gaacacaagg agatatgtcc aaagtaattt caaacaatgg
     5701 gaatatcgtg gatacgacta atacaggaac atctactatt tccttgtcct attttgatcc
     5761 aattgcttta aaaacaatga ctgcatctgc tgtgatccat gttcgtgctg atcaaacagc
     5821 tatcaaagga aaagatcttc acttaagaac aggagagagt tacgccccta aagatcttgt
     5881 tgaatatgta acaaaaagcg atggaacttc aggaaataaa gaagaaatca aaatgaacgg
     5941 gacagtagat actacaactc cgggagaata tcccgttgta ttaacttata tagactcgaa
     6001 aacatcaaat gtggcagaaa caacagctgt agtttatgta gaagcatctg ctgcttcatc
     6061 gactgtcatc actcatttta tagatagtca aacaaataaa gaacttcaag cagaaacaca
     6121 tatgagtagt gtaaatcgta ttcctgattt gcgcctacct gctgaatttt ctgatcgagt
     6181 gccaaatata gatttatcga cttatgaaca aaatgggaaa gtcacttcta tttctgattg
     6241 gatgcaagca aacggattag acagaaaaag tcactggtcg gagatccttg aagtacttca
     6301 ctcagaactg atgaataata ggaagcaatc aggaggggaa attaccttta cttatgttta
     6361 tataccagac aatcgttcat tagaaggtca tgatcttatt gttcatccaa acgaaaaaat
     6421 aaacaaagaa gagttgatcc aatcagcaac aaattcctta ggtaaacccg taccgttaaa
     6481 ggatgtatcg gttacaatca atgaagtacc attggaggat ggttatttga ccaaacaaac
     6541 aggtgatttt acgattatgt atagttatca tgacccgtat tcactccaag aactccatgc
     6601 tcagtcacta ttacatgttt taccattaaa caaacagata gatcaaaaag aacaaaaaag
     6661 acaagaagaa agcttgtcag aaaaaaaaca acaaatggct catgcagttt ctccaacagg
     6721 gaaagtaaaa caaacaagaa gcctagagtt agcaagaata tctagaaaaa tctcagaatc
     6781 taataaaacg ataaggcaag aagctcattt ggccccacaa gtttctggat tggaaaatga
     6841 aattttagag cctaaaataa aacaacaatc agaaaaagaa tttgttgcta aacagtcgga
     6901 agatcagaag gaatcagatg accagaagga aacgaagaaa aaacgcttgt caactattga
     6961 ttccaccgat gagcatctgc agccgcaagt accacttcct agtccgggaa cacccgcacc
     7021 tggtggaggt attccttctt ctgctttagg agatttcatg cgaggtatgg caggaacatg
     7081 ggtatacgct aatcgaaatg aatttgacgc agatgactgg ttctgattta tatctctatc
     7141 tgttatagtc aaataagtag ctgagtcata tgttatttgg cataatggag acgaggaggg
     7201 atagaaaaat gttagataaa acgttacctt acgcagaaat ctggatgaca agaccacttc
     7261 aacaaaatgt tccaatcacg cctttagcgg aaggttttga atttcgattt tatcaaaaag
     7321 aagatgaatc tgcttgggcg gagattgaga cttccgttgg ggaatttcaa acgacagatg
     7381 aagcacttga gtattttcaa caaaactttg ctccttatcc tgaagaactt gaaagaagga
     7441 tgttttttgt agagacaaaa aaaggagaaa aagtagcaac ctgtaccgct tggcgaaaaa
     7501 aatcaagaga gcaagtgtat ccggtttttc attggttagc agtgaaatca gattaccaag
     7561 gaaaagggct cgcaaaagca ttgactgcca gagtcttgca agaatttcct accctccata
     7621 cggacggacc aatctatctt cacacacaga catggagcca tcaggcgatt gctctttata
     7681 aaaaaatggg ttttactttt attgctgaaa atctagacgg cacacctaat ccagattatg
     7741 aaaaagttat gcaggtttta agtaaattag ataaataacg aaatggtgaa ataagtcctc
     7801 agtattggga taaaaaacga aatagtcatt cctcatatct tacttttttg agttaatact
     7861 atcggataac taatggcatg ccatacattc aaaaaagaag gggcagtgac aaaagtattg
     7921 tcactgcccc ttctcttgtt ttttagcatg ttttatcgtt tgattttttt aggaataaaa
     7981 ttcttgatga acgtaaattt ttggtaatcg tttcgactat agaggtaacc aaatacactg
     8041 aaaacaactg ctccaataaa attaacaaat aaatccttca tagtatccat gattcccacg
     8101 tctaagtaac cattttggat gattgtttta tctgttttac catctgcatt ttgactttca
     8161 atgattgtcc gagtgatatc tggaacatga tagacagtgt ttccgtcttt acttaactcc
     8221 acactattga tttgctggat gatcgtatct ttttgcatat cgaattgcag taatttatct
     8281 gctgaaaatt ccacaaactc ccacataaca ccaactgtca tcgaaaaaca gaaggaaaca
     8341 actgctagta ataaaggagt caagttcatg gtttttgtat ttttattgag caaataaaca
     8401 agggaaaagc cgacaccccc agctaaaaat ccgctgaatg catgtagaaa agtatcccac
     8461 attgaaaaat agccataaaa atcacttaac tctcctaaaa ctgttgaact aaaaataaaa
     8521 gataacaaaa tgatttctag catatttgga atctgtatct ttaatatctt ttccagaaaa
     8581 taagggattt caaataaaat taatgtcagt aataaaagca ttgtatttcc ccagtgttgg
     8641 ttccagacct gatccactag cataataacg acgatgatac gtaataaaat atagattccg
     8701 tttgtgattc tacctgcagt ttttgtactg ttcgtaaaaa aggttttcaa atgattcata
     8761 aaataactcc ttcatgtata tccttaatta tactaagaag cgtgtgttta ccaaagctat
     8821 atgacttaaa gaaaaacaga gttgatattg tgaaaaaaat cacttaatat agtataagga
     8881 gaaaaggggg atacaaatga aaaaattagt tgctggttta ttaacagccg ttgcacttct
     8941 tgctatgagc gcatgcggcg cagatcagaa aaatacagcg cagacaagtt ctagtacgaa
     9001 ggaatctgcc gaagtatcat caggcgcttc tgaacaagta tatacagatc caaaagaaat
     9061 gaaagaatct tatgatgtcg tgattattgg agctggtggt gcagggatgg cagcagctat
     9121 cgaagcaaaa gatgctgggt tgaatccagt aattttggaa aagatgcctg ttgccggagg
     9181 aaacacatct aaatcatcaa gcggtatgaa tgcttcagaa acaaaatttc aaaaagaaga
     9241 aggaatcaaa gactcgaatg atgccttcta tgaagaaacg ctaaaaggtg gtggaggaac
     9301 gaatgataaa gaaatgcttc gatactttgt cgatcactct gctgatgcgg tcgattggct
     9361 agatcaaaac ggtatcaaac tggacaactt aacgatcact ggagggatga gtgaaaagag
     9421 gacacatcgt ccgtctgatg gctcggctat tggtggatac ttagtggagg ggttattgaa
     9481 taacgtccat gagcgggaaa tccctatttt tgtcaacgca gatgtgacag acattaagaa
     9541 aaatggggaa acggtcaatg aagtgactgt acatgttcaa ggagaagaac caaaagaggt
     9601 caccggaaaa gcaatcgtag ttaccacagg cggttttggt gccagcaaag aatttattga
     9661 aaaatatcgt cccgatttag ctgattatat tacgacaaat caagaaggat caactggaga
     9721 tggtatcacc atgattgaaa aattaggtgg acaaaccgtt gatatggata aaatacaaat
     9781 tcatccaact gtgcagcagg atgagggggt cttgattggt gaggttgttc gcggagaagg
     9841 agcaatcttg gtcgatcaag aggggaaaag atttgtcaat gaaatggata caagggataa
     9901 agtatctgca gcaattacag cattgcctga aaaatcagct tatttgattt ttgaccaagg
     9961 cgtgcgtgat cgtgccacag ctattgaatt ttatgaccaa aaaggatatg tcacaactgg
    10021 aaagacaatg gaagaattag cagaaaaaat cgatttacca aaagaaacac tagcaaaaac
    10081 agttgatgga tggaatacgg atgttgcgga gaaaaaagat gctcaattca accgtgccac
    10141 agccatggaa catgacttat cgtctccgaa ttattatgcg atcaaaatcg caccaggaat
    10201 ccattacacg atgggcggtg tgaaaatcaa tacgaacact gaagtattag ataaagaaaa
    10261 ccagccaatt agggggttat atgctgctgg tgaagtcaca ggtggcttac atggaaacaa
    10321 ccggatcggt ggaaattcag ttgcggagat cattattttt gggcgacaag cgggcataca
    10381 agcagctcga tttgcttcgg aaaatgaatg aaatagaacg taaataaaaa gaggttgtga
    10441 aatcagcgtt ttgagctaat accgagggtc agctgattga acactgttta gtgaagaggt
    10501 tgtgaaaaag ctgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
    10561 tttttaactt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttattcgga
    10621 aaaagagcgt gggacaaaag taaagaacac ttttgtctca cgctctaaac acgtataaac
    10681 ggcggaagca gaagaaattc cttcggaaat aagctgaaat tcacaaaaat ttgaaaagca
    10741 attttcgtga atttcttctt atttcttgga gttaaacgct tctgtcccag cctctttttt
    10801 gatcagcatg attttattca gttatcttca aaatgatttt tccgatgttt ttgtttgctt
    10861 ccatatattc atgcgcttgt ttgactgcgc tgaattggaa tgtacggtca atgattggcc
    10921 gaatcttgcc attttctaga aaaggcccag ctttttgcat aaaagtttgt gcgagctctg
    10981 ctttatactg atcacttcta ggtgtcaata atgtaccaag cagttggaca cgtttcccaa
    11041 tcaatacacc aaggtctatc tcaggcacga tggtcccacc tagcatacca atcaagaccc
    11101 aacgtccatc aacggctata gaagctaaat tcttttccca gtaagaagcg ccgatgaaat
    11161 ccaaaataac atcgactccc cgaccttcag tgatttttcg tacctcttct tgaaagtctt
    11221 gttttttata gttgatcaat tcatctgcac caagttcttt acaaaaggcg agtttttctt
    11281 ctgatcctgc agtaacgatg attttcgcgt gagaaagctg tctagctaat tggatcgctg
    11341 ctgttcccac accacttgct cctgcatgga tcaagacagt ttcgccttct tgtaattttc
    11401 caagccagta aagtgtttga taagcagtca aaaaaacttc tgagattcca gcagcagaaa
    11461 catagtctag cgtatcaggg agaaggattg cacgatcggc aggcatcaca gcatattcgg
    11521 cataaccacc tagattgact aatccgtata cttttgtccc aggagtaaaa gtggagatat
    11581 cacttttatt ctcaactacc tctccagcta cttcgactcc caaaataggg tagggaggtt
    11641 tcaaagagac tgattctctt ttcataatat ctgttcgatt gacagctgct gtatggactt
    11701 tgatcagtaa ttcgccttgt tttggtttag gaacaggcac ttcaatttgt tctaatacat
    11761 ctacagaacc aggatgcttg attgaaatgg cacgcatgga tctattcctc ctttgcccat
    11821 tcttggaatg ctgtattcaa ctctttgcta ccttcagaaa gtactagagt cgtacgagaa
    11881 atatccgttt cttccactag agcggcaagt acagcagcaa ctgtagagcg agtgatcgtt
    11941 tttgatgcct tctcattagg cttagttaat tgaatggaag taacttcttc atcgttagtc
    12001 aatgtgactg gttgaagaat gacaaaatct aagttagttc gtttcagcca ttcatctgca
    12061 taatgtttag taatataata atctgtcatg gactcaggcc attttgctgg ttcatctgca
    12121 taaacagcac tgaccatcag atagcgagag acatgcgcat tttcagctgc gatcactgtt
    12181 ttgattgcgc catccaagtc tacttgcaga agattctttc cttgagagcc ggcagcaaaa
    12241 atcaatacat cgatgccttt gaatgcttcg gtcatttttt ccacggacca agttaaatca
    12301 aaagagacat acgaaacatt ctcttttttt actaatgttt gggaagcaac atctctcacc
    12361 cctgcaaaaa tttcatggga acttggagct aaatctttta tcaggtgtcg gccaatttgt
    12421 ccgtttgcac ctacaacaaa aattttcatt tggatcatcc tttcgacgtc aaatctttcc
    12481 attcaatagt aacaccaaaa gagaaaaaaa tcagagatcg gctacgatga ctatcagtta
    12541 gtaagagaag ggtgcttgaa gtatcttaac aagacattgc atactgctgc agtcgcaaga
    12601 cctgcgacga ttccttcagg tataccactt gtaaaaataa ccgctagaat agctgaataa
    12661 acagcattta aatttgttcc gatgactttg gcataatctt gctggaataa aaagtagatc
    12721 atattcatca ctaaaatcgt attggtcaat gaaccggaaa gtccagctaa gaataaagaa
    12781 acggaatctg ctttttgttt cattagtttg cgcagacctt tataaacgaa ataaggaacc
    12841 accccaatca agatgcgagg aataaacgcg atcagcaagg ctttccagct tccatgttct
    12901 gttccgatga ctgggataaa cggagaaaag acaaaagaca aaggtgtttg gataactgtg
    12961 ctacggatca tgctgatcag tccaaatgta ccgccaagaa aagcacctag tcttggtcct
    13021 aaaacgatcg aagcaatgat tacaggaata tgcatggttg ttgcattgat tggaccgata
    13081 gggataaaac ctaaaggcgt aacagctaat aaaatcaaaa tagctaaaaa catcgcagtt
    13141 aatgtaaagt tttttgtatt tttcataagt actccttttt tctaagcatt tctttcatta
    13201 agagtcagca tgacctgttc gatgatcgtc tgaatatcag ctaaggcacc ttttccaaaa
    13261 tctccacaag ctaaaagaga ttctcttggt tcaatttcct gatagccgac agatctcaat
    13321 gtttccagat tacgctgagt gatcgggttt tgatacatat tcgtgttcat ggcaggggca
    13381 atcaattttg gtgttcccac tggaagcgcc attgcgactg ttgaaagaag atcgtctgca
    13441 atgccgtttg ctagcttgcc gataatgttt gctgtagcag gcgcgatgag aaacaagtca
    13501 gcttgttttg ctagttcgat atgattgatt acctgcggat ttgattcttg catgacgtct
    13561 gtatggactg cgcgcttcga cagagattgc aaggttaatg gcgtgataaa atgtgtgctg
    13621 cttttagaca taatcacatc tacctgggca cctaatttga cgaattgact tgtaagatca
    13681 gcgcttttgt aagcagaaat acttccagta acgcctagta agatcttttt cattttgatt
    13741 cctccagtct aattttctca gtaatcaatg cagcaatctc agatttactt tgagcttctt
    13801 ccactgttcc atctttagat aagagatagc cgtggtgtgt ctcgccatgg atttccgtca
    13861 aatcatttgc gaaaataaaa tcagttttgt tatttatcag actatttttt gcgactgcca
    13921 gaagagattc ctttggtaca tctactaata gtttgaaacc aatgattttt gcttttggct
    13981 gccattcacg tagataagaa atgatttttg gtgttttctt caaaacgagc acaagatgct
    14041 cggtgttaga agagatcttt gaaacagtgg tatctgtctg ttcattttcc gcaaaccaat
    14101 tgtccagttc ttcttgcgtt gaagaagtgg gtaggttttt tgccagctgt tcttctgaaa
    14161 aactaaaagc aggagtaaaa tcactgactg ccatactgtg gataatcgca tcgtagtgtt
    14221 cttttttcgt tagttcttct aattgtaaaa ataagtccag tgcagattcg atcgtataaa
    14281 tcgttatatt ggagtgtctt ttcggtttca gtgcttgttt cgtagtcacg taatcgattg
    14341 tggtatccgg attggcagct aaataatcag ctaatgcttg ccctaatcgt cctgtcgaat
    14401 gatttgtaat agcacgtact tgatcgattt tttcagtcgt tcctccagct gtgattagaa
    14461 tcttcattta tggtcaccta catttactag tgttcttcct tggtgtgttc cagcaagtag
    14521 tttagatgct gtttcaggca attgatccag agtaatctct tggacgacca gttcatctgc
    14581 aatctgcaaa tccgccatct gttgccataa agaaagacgt tgatctattg gtacattgac
    14641 agaatcaatt ccaatcaact ggatgtttcg cagaataaaa ggcaagacag tcgcgtttag
    14701 tttgattccc ccagcattgc cacataaagc tactgcaccg ttataagaga tcaatggaag
    14761 aagactgctt agctgctcgc cacctactgt gtcgatgaca tagtcgattt gctgttttcc
    14821 taaagctttt gttgtctctg gcagaaattc atcaggtcgt acgacttgca aagcacctag
    14881 actttttagc catgtgacag actcttcttt tctggaaaag gcaatgattg actggaatcc
    14941 tagtttatgt aacagggcta tcgctgtact gcctacaccg ccagaagcac cagtaacgac
    15001 aactttttta tcggaggtca taccttgacg gattaaagcg ttcacacaca acatagcagt
    15061 aaaccctgct gtaccaagga tcatcgcttg acgcagcgtc atattttttg gtagaggaac
    15121 taaccagtct cctggtactt tttgatattg gctataaccg cctggatggg tgacgccaag
    15181 cccaaaacca gtagcaagta caagatcttc ttttgaaaaa cgtggattgt tactttggac
    15241 gacagttccg gataaatcaa tccctggagt catcggatat gttcgtatca cctgaccaga
    15301 ctcgctcatt gccaatgcat ctttataatt gacatcagaa taggcaattt ttaccaagac
    15361 ttcattttca gccaactcag taaatggcag atcactgatt gctgtatgga aaacaggttc
    15421 ctttattacc tgaaaagatc gaaaagcgtt cattcgtgag acactccttt taaaattttc
    15481 ttttatcata ccataaagcc tactctttta ttcttgttct tccgtaaatt tagacaaaaa
    15541 ttaggtgaaa aataaagaat caaacaacta gaatttattc caaaagataa agaaatattc
    15601 agcaaaaaaa attttacaaa gggttgcctt tttcaataaa tttcgtatac taatacgagt
    15661 ggtagtaaac aggaagttta ctattagaaa acttcgattc ggaggaaatt atggaaattg
    15721 gtgagaagtt aagaaatttg cgcatccaaa agaatttgac acaagaagaa ctaggcgaac
    15781 gcacagattt gtcaaaaggg tatatttccc agttggaacg agatttaagt tcaccatcaa
    15841 tggaaacatt cttttctatt cttgaagtct taggtgtgac tccagaagaa ttttttcatc
    15901 aagaagcagc gaatctgcaa gtggtttatt caaaagaaga tcatacggtt tatttcgatg
    15961 aagaaaacgg gtatgaattg gaatggctcg tggctgattc gaatgaaaaa gaaatggagc
    16021 ctgtcttgct gacttttgaa ggtgcaggag aatataagac gtttgaacct tcattatctg
    16081 aaacgtttat ttttgtatta gaaggggaat tagagttaag cttaggagag acggtctatg
    16141 tggcaaaagc aggacagtcg atctattatc aagcgacaaa acaacatcaa ttaaggaatc
    16201 atctcaaaaa acgaacaaaa gtattgattg ttgcaacgca atcatatttg taatataggg
    16261 ggtaaaaacg tggggaaacc aatcatttca tttgatcaag tagtgaaacg ctatgatgat
    16321 gaaacagtat taaaaaaagt aagttttgag atcgaacaag gaaaatttta tacactgctt
    16381 ggtccttccg gctgtggtaa aacaacgatc ctacgtatta tagctggatt caccgaagct
    16441 acagaagggg acatctattt tgaagggaaa cggttgaatg atttgccagc taataagcga
    16501 caagtaaata cagtcttcca agattatgca ctttttcctc atatgaatgt ttttgataac
    16561 gttgcttttg gattgaagat caagaaaatg tccaaatcag atatcgaaaa gaaggtaaaa
    16621 gatgctttgc gtatggtcca gcttcctgga tacgaaaaac gggagattag tgaaatgtct
    16681 ggtggtcaaa gacagcgtgt agcgattgca cgagcaattg taaatgaacc gaaagtattg
    16741 ctattagatg aaccgttatc ggcgcttgat ttgaaactac gtacagatat gcagtatgaa
    16801 ctgcgggatc tgcaacaacg attaggaatc acgtttattt ttgttactca tgaccaagaa
    16861 gaagcgttgg caatgagtga tgagattttt gtcatgaata aagggaaaat cgtccaaagt
    16921 ggtacacccg tagatattta tgatgagcca atcaatcatt tcgttgctga ttttgttggg
    16981 gagagcaata tcgtggacgg tgtaatgatc gaagataatc tagttgagtt tgttggtaag
    17041 caatttgaat gtgtcgatgg cgggatgcgt ctaaatgaac cagttgaagt tgttttacgc
    17101 ccagaggatt tgacgatcac gacaccagat aaaggaaaac tagtcgtaac ggtcgatact
    17161 cagctgtttc gtggtgtcca ttatgaaatc atctgttatg atgaacagca aaatgaatgg
    17221 atggtccatt caacgaaaaa agctaaagaa ggaagcaaag taggattggc ctttgagcca
    17281 gaagatatcc atgtcatgcg tttcaacgag tctgaagaag aattcgatgc acgtcttgac
    17341 agctacgaag aatagggggg acaagaatga aaacaatgcg caggatctat tccgtccctt
    17401 atattttgtg gctcggttta ttcgtgatcg cgcctgtatt aatgatcatt tatcaatctt
    17461 tttttgatat gaatgggcaa ttcacgctga ataattatct atcttatttt acgtcgggga
    17521 catcgctttc tatgacgatc aattctgtat ggtatgcatt tttgatcacg tttttcacgc
    17581 tgatcatcag ttacccgact gcttattttt taacaaaact gaagcacaag caattatggc
    17641 tgatgctgat tattttgcct acatgggtga atctgctgct taaagcttac gcatttattg
    17701 ggattttcag tgtgcacggc agcgtgaatc atttctttga ttttatcggg atcgggccga
    17761 aacagatatt attcacagac ttcagttttc tgttcgtggc aacgtatatc gagattccat
    17821 ttatgattat gccaattttc aatgcattgg aagagatgaa tccttctttg atcagtgcta
    17881 gtagagattt aggcgcgaat agctttgaga ccttccgacg agtgattttt ccgttatcat
    17941 taaatggtgt gaaaagtggt gtccaagcag tatttattcc ttctctttct ttattcatgc
    18001 tgactcgtct gattggcgga aatcgggtga tcactttagg aacggctatc gaacagcatt
    18061 tcttggttac acaaaactgg gggatgggtt ctacaatcgg tgtgatttta atcattgcta
    18121 tgttcatcgt gatgctcctg acaggcgaga agaaaaaagg aggtcgctca taaatgaaaa
    18181 aatttaaatg gtcgtatctt tatttaggga tcgtcttttt attcctatat gcaccgatct
    18241 tctatctgat tttttattcc ttcaatgaag gaggaacgat gaacagcttt acaggattta
    18301 cttgggaaaa ttatgaagct gtttttgaag atacacgttt gatcattatc gtattgaata
    18361 cgttcatgct ggctttctta tctgcattga tcgccacgat catcgggaca tttggggcta
    18421 tgggaatcta ttacacgaaa aaacgacgtg cacggacagc gttgttgagc atgaataaca
    18481 tcttattagt ctctcctgat gttattatcg gtgctagttt cttgattttc tttacactac
    18541 taggattcgg attaggtttt cagagtgtat tgctttccca tattgctttc agcattccaa
    18601 tcgtcgtctt gatggtcttg ccaaaattgc aggaaatgaa cgattcaatg gtcgatgcgg
    18661 ctagagacct tggtgctaat aatttccaag tagtcaaaaa tatcattttg ccttatcttt
    18721 ctccaggaat catagctgga tattttatgg catttaccta ttctcttgat gattttgcgg
    18781 ttacattttt cgtcacagga aatggcttta cgacgctctc agtagagatc tattctcgtg
    18841 caagacaagg aatcagttta gaaatcaatg cgctaagtgc gttagttttc ttgttctcca
    18901 tgatattggt cattggatac tactttatta gtaaagaaaa ccgtccaaaa cggctgaaga
    18961 aaaacagaag agtacgcgag ggggtggcac ggctgcgatg aaaaaattac aatctctgtt
    19021 tttaggtatt ctcatcatta ttgcggtgct gctgcttggt gttcgtcaac ttgaaaaaac
    19081 aagtggcatg agtggagcaa aggtacttac catctataac tggggagatt atatcgatcc
    19141 tagtttgatc acgaaatttg aaaaagaata tggatacaaa gtgaattatg aaacatttga
    19201 ttctaatgaa gcgatgttca caaaaatcca gcaaggtggg acaaactacg acatcgctat
    19261 accaagtgaa tatatgatcc aaaaaatgat caaagaaaaa ctagtacttc cattagatca
    19321 ttcgaagatc aaaggattaa ataatattga tccacgattt ttagacttgg attttgatcc
    19381 agataatcag tattcgattc catatttttg gggaacttta gggatcgtat ataacgataa
    19441 attctttgat gcaaatcaaa ttaagcattg ggatgatttg tggaagccgg aattaaaaga
    19501 cagtttgatg ctgattgacg gtgcacgaga agttatgggg ctttctttga atagtttagg
    19561 ctattctttg aatagtaaga atatggcaca gctgacagaa gcagcaaata aattgaatca
    19621 tttaacacca aatgtcaaag caatcgtggc agatgagatc aaaatgtata tgatcaatga
    19681 agaagcctcc gtggcagtga cattttctgg cgaagctgcc gatatgatgt gggaaaatga
    19741 acatttacat tatgtgatcc caccagaagg atccaatctt tggtttgata atatcgttat
    19801 gccaaaaacc gtgaaaaata aagaaggtgc ctatgatttc atcaacttta tgctagaacc
    19861 ggaaaatgcg gcacaaaatg cagagtatat tggttattct acaccaaatg aagaagcaaa
    19921 agcgttattg ccaaaagaca tttcgtcgga cgaacaattc tatccatctg atgacacgat
    19981 ctcccatctt gaagtctaca aagatctagg atcgaaatac ctaggcatct ataatgacct
    20041 attcttagaa ttcaagatgt ataggagata atggcaaaac tcagtaagaa tggggactta
    20101 tcaacgttct aaagagctaa aaatcgtcct ttttctatct gagttttcca atcttctacc
    20161 aaaagcggat gaaacgccgc tttttttgtg ttattttatt ttttctacca cgtttttcta
    20221 ccagagaaaa gtggacaaaa ccattgtaaa atagggcccg agacgggcta gtaaatctaa
    20281 gattgaaaaa gttacagaag gataaagtaa ttggaaacta tgcaaatata cttaaccctt
    20341 ctgtaatcta ttaataaaac taatatatga atccagttca atatttgtag ctatgaaaaa
    20401 acataaaaat catattagat aaaaactaaa ttggtagata aattattttg tcagatatct
    20461 gaggcaaata ttcgactatt tgtgtttcaa agtaaaaatt ggaatacaaa tatagaatag
    20521 acatattgca gccgatagtt tattatgctt ttagacacat taaactggag gaaaaaatga
    20581 aaaagagcgc taaagatcga gtttttgatg agctgatacg actaacaggg aatatgtctt
    20641 ctgtcactgc cgagaaaatt tcgaagaatc taggtatctc tcgtcagaat gccagccatt
    20701 atttgacgag attagtggaa gataaaaagg tcgagaaatt accgggaaag cctgttttgt
    20761 ggaagccttt agatgaatat gcggttgtag ataatacgga gcaaataaac gaagcctttc
    20821 attctgtagt tggtcatgac ggaagtctga gagaggtcat tcaaaaatgt atagccgctg
    20881 tcaaatatcc gcctaacgga ctcagtgtat taataaatgg agccacgggt gttggaaaaa
    20941 gttttttagc cacaaaaatt tttgaatacg ctatccatga gcaaattatt gaaaaagatg
    21001 caccatttgc tatcttaaac tgtgccgatt atgcggacaa tcccgaactg ctttcggcaa
    21061 cactgtttgg atacaagaag ggggccttta cgggggctga aaaggatacc gatggtttat
    21121 tggcaacggc caacaacggc tatctttttc tcgatgaggt ccatcgccta tcgaaagaaa
    21181 atcaagaaaa gctctttcta tttattgata ctggaaacta tcgtccagtc ggtgaaaatg
    21241 taaattggca ttctgctaag gttcgtttta ttttcgccac gacggaaaaa ggtgaaaatt
    21301 atttattaga cacctttgat cggcgtattc aaattagtgt tatgttgcca acttttgaag
    21361 atcgccccat tcgagaacga ttagagctga ttcaattatt ttttcaaaat gaagcggatg
    21421 ttttacaaaa agatattatt gtttcaagag aagccttgtc tttaatgtta tctcatccct
    21481 ttagtgggaa tattggtaag ctgaagaata tcattaaaat cagttgtgcg gatgtgtata
    21541 gtcgaacaca agaagaacca ttaacgattg ggaaaaatga gatcttgatt cagttaaata
    21601 tgctggaatc cgaagtagaa agcttgccga ttgctagttt attgataaag aaaaatcaaa
    21661 agataaaaac ggatcgaatc aaaccgtttg attatgattc gattttggaa aaaattactc
    21721 agctgataaa tgaaggtaat ttcaatgaaa atttttcttc gataaagaat gaagtacagc
    21781 atttggtgca tcacattgat aaggattctt ttttatcaat gagtagaaaa ttgatgattc
    21841 agatgtttag aaaggtctgg gtatccgttt taggaaaaac gtacggattg acgacgagtg
    21901 gacctgttgc agaaattatt agcagatcct atgtcatttc cccaagctat aagacagact
    21961 taaccgggat aaatcgtaca ttagctgcaa atctacctcg gacgacttac ttatgtaatc
    22021 agttcttgga gcatttacca ccgctctcag aaaaggacga gaactttcta agactgctta
    22081 ttgtcgtgac tttatctgat tatgtagatg aatccatcga gctgaagggc ctgttgcttg
    22141 ctcacggaga tagtacggct agcagcattc aagcagtagt gaatcaatta tgcggcaatt
    22201 atgtttttga agcgttggat atgccagtag agagtaatgt gtcagagatt gtcgaatcga
    22261 caaggaattt cgtgaaacgg caagtgaata cagatagtct agtgctgatc gtagatatgg
    22321 gctctttaaa tcaaatttac acacagatca agaacgattt aaaaggggag ttacttcttc
    22381 tgaataattt gacgacttcc attgcacttg atattggctt gaagatgacg atgaatgcgc
    22441 catttaaaca gattgcggag gatgcagcag acaagtattc aatcaatgtt caatactttg
    22501 aaggcttttc tcaaagtagc aacattatca tttcctgtat gtcgggtttg gggatttcgg
    22561 acaaattgaa agatgttttt cgtcatcatt tatcggatga atccatcgaa gttttcacga
    22621 aggactacag agaactacgt gaattaatcg accaaaatga tgaaacttat tttgacaaga
    22681 caaaattggt catcacgact tcggatcttc cacgttcctt ttcaattcct aatattaatg
    22741 tttatgacat cttagacggt gatggagcag ccaatttgga gcatattttg agtcctgaaa
    22801 tgaagccggc agaatttaac cgcttgattc aggagctagt aaaattcttt tcgttggaag
    22861 gaattgcgga ccgtttgaac tttctgaacc caacgatcgt gatgagtgaa gtggaaacag
    22921 tcatttctaa atatgaaaat tactatcatt tcactttaaa tggccgtgta aaactaaatc
    22981 tctatatgca tacggcattg atgatggaac gtttattctt ggctcggaca gaaaaatctg
    23041 aagaaccgaa ttatgatttg aaaccagatg aagatgaatt ttattatgtt tctagaagta
    23101 tttttcaatc aatggagatg aaatataatt ttaaagtcaa tgcttatgag ctttcgctgc
    23161 tctatgaatt attaggaccg tatattcaaa aataaagtgt ctaaaaaagt gtctaatctg
    23221 ttttttttag gttagacact ttttttaatg tgaattaacg tgattaaacc aatgttttta
    23281 aaagttggca caggaattgc ttatataaaa gtgaacagaa agaaaggaat taaccatatg
    23341 aagaaaattc taatagcgac tcacggtcac ttagcttcag gctttcttag cagtattcaa
    23401 ttactgacgg ggaaggttca agagattacg gtgattaatg cttatgtgga tgagtgtgat
    23461 tttgaacagg agttgaatgt atttgtaaac caggtgaacg agcaggatca gatttttgtt
    23521 tttaccgatt tatttggcgg aagtgtcaat cagaagatta ccaaaacctt tttggagaaa
    23581 gagattgctg taactatttt gtctggcttt aatctgccaa ttctgctcga aatagtattg
    23641 gcaaccaagg aattaacaaa ggaggatatt caggaactgg taaataaatg ccaacaggaa
    23701 ttaaagatga ccattcttga tgaggtacat gtagtaaatg aagaggaaga ttttttttag
    23761 gaggaagaaa aatgattaaa gcagtgcgaa ttgatgaacg attaattcat ggacaagtag
    23821 cgatgacttg gacaaagagt ctaaatttaa ccgggttagt agtagcaagc gatgaggcgg
    23881 ctaccaacga tattcaaaag atgacattga agatggctgc accatcgaat gtcaaagtca
    23941 ttattaaaac agttgatgac gcgattcatt tgttaaaaga tccgcgggcg aaggacatgc
    24001 gcttgatggt tttagtccct aatgtcaaag atgcggtaaa agttgcgaaa gctttcccaa
    24061 cggaaatcga attaatgaac gtggggaatg ctgggaaaat gacaccgcca tcggaagata
    24121 agaaaacctt atcaaaggaa gtgatgttaa cgacgtcaga aattcaagac ttaaaagaat
    24181 tagttgaact ttatccagat accgtttttc agcctacacc ggcgatggaa aaacgttcag
    24241 ctatctctat tttgagtgat ttttagaaaa aggaaggaga aaaattatgt atgatgcatt
    24301 tgtagtcgct ttggccgttt ttattggagt tgctggacat gaaatgttcg ggatgtccat
    24361 gctgagtcgt ccgattgttg ttgctccgtt agcaggagcg ttgatggggg atttgcagac
    24421 ggggttgatt gtcggggcgt cactagaagc catctttatg ggtgtcgtca atatcggaat
    24481 ctctagtacg gcggagcctt ctttggctgc tgggctggct acagcgttcg caatcaaaat
    24541 gggaggaaac gtggatgcga ttattcccat tgtctttcca ctagcagtat taggattaca
    24601 gttaatgaat atgatttttt cttttgtatg tggaccgatg gctgctaaat ttttcaaatt
    24661 tgcaaaatct ggtgatcaaa aaggaatcat caatctgcac ttctttatgt ggtttgtcca
    24721 ctatgcgctt tatgctctta ttccattctt tgccgtttta tttggagcag atgttgtcaa
    24781 aagcgtcttg gataatattc cagaggtcat catgaacgga ttaacagtcg ctggaaatct
    24841 gctgccggca gttgggatgg cgatgctgtt acggatgctt tggagtaaaa atattgctgt
    24901 gtggtttttc tttggggccg ttgttatggc gtatctcgag ttaccattga ttgcaattgc
    24961 cgcagttgga acgattattg caattgttat agcccaaaga gatctacaac taaaaaatat
    25021 atctgttcat gcagttcaaa gcgatgctgc tgtaaatgca acgcttgacc aagaagagga
    25081 ggatttcttt caatgaaatt agctgatgga atttctaaag atgagaaaaa attggttcgg
    25141 aagatgtttt ggcgctcgat gactatgtat gcttcggtga atccggtgac gatgggcggc
    25201 ggtggtttcg cctattctat gatgcccttc attaatcatt tctacaaaag tgaagaagat
    25261 cgagctgcgg cgctggaacg tcatacacag tatttttcga cgaccattcc ttgcgcgtcc
    25321 tttgtcatgg ggattgcggc atcgatggag aaggaaaatt ctgaaaaagc tggttttgac
    25381 gtggaaagta tcaacgcgat caaaacgagt ttgatgggac cattggctgg aattggcgat
    25441 tcattgttct ggggagtttg gcgtgtcgtt accgcgggac tagcgatcaa cttagccaat
    25501 gccggaaata ttttggcacc aattatcttt ttagttatgt tcaatatacc taattacttg
    25561 atgcgatact atggcggcgt tttaggctat tcattaggct ctaaatatat tgaaaagctg
    25621 tatgcgaacg ggttaattga aattctgaca aaagctgcta gtatcttggg tctgatcatg
    25681 gtaggtgcaa tgacgatcag tatggtcaaa ttcaataccg ttttgagctt ttcaatgaag
    25741 ggcgaagaac taatgaatgt ccaagaaatc ctcgatagta tttttaaagg aattgtaccg
    25801 ttattggtaa cattgagctg tttcaaatta ctagataaaa aagtcggcgt catcaaaatt
    25861 atttttggaa tggtcgtctt gggaatttta ttgtcattac ttggaatcgc atagtaggaa
    25921 gctgcagcta ctaggctgca gtttttttag caaggaggga aaagatgact attaatgaag
    25981 taatttattc acccaaacac ccatttttta atgctgagtt aaacgacgga aatgtgacta
    26041 cttcaaacga atacagctac tatcggaata ttcctgatgt aaagggattg accttcgatg
    26101 taagtaatca aaagacatta gcaaaccttg atgtttgcgg gacgattcaa acgttgacct
    26161 tttatcgaga aaatttacta actgaggaaa aaccaggtgt ttgggtcaat aaacagctct
    26221 ctcaaaccaa ttcgttatcc ttaaaggttg aagtaaacgg gattgtctac catttgtcag
    26281 aatcggatca tcgtattgaa gtcgatgtga ttcaagactg tttgcctaga tatattcatc
    26341 attattcgac gtttaaggtc attgtagtat cctttgctcc catactggct aataagcgtt
    26401 taagtatgct tgttcaacag gtttacattg tgaatgaaac acacgaaagc cttcaagttt
    26461 cagtgaaaga tgtgccttcg tatcaagaga agtattcgga tcagcaaaat gtgttgattt
    26521 ctcaaaaagg aaataaggac acgatcgcac aacaggaagt ggcaagcttc gccattgctt
    26581 ttgtggaccc aaatgctttt gaagaagtaa tgacttttca ggaatctgat atcgaaaaat
    26641 ggctgaagga aacattgaac tattttgctc agctatttgg gcagctgtca atgccaaacg
    26701 atagagttgt ccatctctat cgtcgtgcac tttatcaaag cttttctagt ttcggtatga
    26761 atcgacaggg acaggtcgtc ggcagcaatt ggggcagcta tcctgctact aatcgaattt
    26821 ggaataagga tatgtattac gcatcattgc cattcaccat gtttgaaccg gagttatgtc
    26881 aaaaaacggt tctatggttt gatcaatatg gcgttaagtt tcctggttca aaatttacag
    26941 gaggtatcaa tcattctctg agtaattcgt tatccagtgc gttactggct agtctttatt
    27001 ttgaacatac tggggataca aaattctttg agcggtgtcc gcaggttcta ctgaatgctt
    27061 caagaattat tgaggacata ttagctcaac gtcggtcagg ggaaccaatg ctttttccat
    27121 ctgtttggtt atcagacgcc tttgcacttg gaaagtatca taccggcagc aatctttgtc
    27181 tttggaaggc ctgtattgga cttgcagaaa tttttgaagc cctagaacaa ctgagtctta
    27241 gcaagcgata caaaaacatt gcctgtaaac taaaggaatc aatttgtaaa caaatgacta
    27301 tcgatggtcc ttttggtgag caatttttgg agggaatcgg tgatgaggag aaaacaacct
    27361 attcagtgaa gcactatcaa aaaccgattc ttgagcaagg gttaatcttt ttaagtgatg
    27421 tgattgtgga tggaaaaatt aatttattga tgcatgatgg agaagaatca gacactacgt
    27481 tgatgccttt ttatcaattt ttagataata aagatcattt atatcagaac accatggcct
    27541 tttctgctag ttctttcaat ccaacctata gcgaggaaat caaaggcatc acttggggat
    27601 tagaatccgg cgccactttt cctggcttta tcactgtttt aatgagcgag ctgcacaacc
    27661 ctcaagcttt cgtaacccga ttagaagaac taatttgttt ggcagattta gacggttcgt
    27721 ggtggtggtg gccgtatcgc ttagaggctc aacaaggaga agtcgtgcga gactttggct
    27781 gcggcaaatg cggctgggca tcgggtcttt ttgtcagcct aatgatcagt caatatttcg
    27841 gattgaaatt caaaaaagga gtattgcaaa ttgatcctgt tgataattta acgttttctt
    27901 ggaagaattt gaagttcggt caagccttca tttcgattga atgtacgcaa tccgagttga
    27961 gtatttcaaa tttgtcagaa aagccattga aaataagtga tacgaaaaaa attcttcacg
    28021 tagaaaaggg aaaaacgatt cacattcaaa ggagaaaaag atgagtatac taaaaaatat
    28081 tacccaattt aaaaaaatcc agagtcgagc aatcactccc gaaaatccaa caggcgagaa
    28141 aggtaaagct gcgatgttgc caagcgagct aggaccaagc cgcaaaggtc gtggcgcaat
    28201 tccgctgact tctggtgaag aaactgtgat tgcggatatt actggaacgg gaataattcg
    28261 tcatatgtgg atgacgattc gtgatcgaac agaatttggc agttttgttt tacgtgattt
    28321 aatcttaaga atttattggg atgggtcgga tagccctgct gttgaaagtc ctttagggga
    28381 tttcttttgt aatgggtttg gagagcgttg cgaggtgaac tcgttgccga tagtggttaa
    28441 tcctacaggg ggctttaatt cctatttcga aatgcctttc caaacatccg ctaaaattac
    28501 gatcgagaat ttacatccga aggatatgtc ctcatttttt tatacgataa attacgcttt
    28561 ggtggacgaa ttggaagaaa atagcctata ttttcacgca aattggcatc gggaacgcat
    28621 taccaaatta caggaggatt ataagttaat tgatcgatta aagggtcaag gctattacgt
    28681 gggtacttac cttgcgctta cctgcctaga acgttattgg tggggcgaag gcgagtttaa
    28741 attctacatt gatggggata gtgagtatcc gaccgtaacc tcaacaggtt cagaagatta
    28801 ttttggcggg gcgtgggcct ttcatgagta cgatgagttc ggacgtccac atgcgaaaaa
    28861 ctattcaaca gcctttttag ggtatcctta ccaatcaaat agagatgcca caagagatcg
    28921 ttttgaaacg ggaaaattga atgccgttca tgcctttggt gacgacgcaa tgccacgaca
    28981 tggtctttat cgttggcatc ttcaagaccc catctgtttt accgaagatt tatcggtcac
    29041 tttacaacaa atcggcaacg atgatgttcg cttatttgag cggcaagacg atgttgctag
    29101 tgtcgcttac tggtattcaa cagaagcttc aggaaatact aaacgtcatt tcactgatcg
    29161 agaacgcttg ccgcgttaat gaagtgtttt tcacatattc gaagggagga acctatgatg
    29221 atatatgggg caattgaagc tggagggact aaatttgtct gtgcagtcgg tactgaggaa
    29281 ttaacgattt tggaaagagt cagttttccc acaacaactc cagttgaaac aatgaagcag
    29341 gtcattgatt tttttaaacc ttttaaggaa caattggcag gcatcggggt cggctgcttt
    29401 ggtccaattg atattcaatg caaatcaacg agtttcggtc atatcacatc aacaccaaaa
    29461 cttgcttggc aaaatttcaa ttttgtagga acgctaaagc aatatttcaa tattccgatt
    29521 gaatggacaa cagatgtcaa tgcggcttgc tatggtgaat atgttgctgg ttctggcaaa
    29581 gggttagcag gtgttgcata cttcactgtg ggaacaggta tcggaggtgg tgccttgttc
    29641 aatgggactt tcgtggaagg gttcagtcat ccggaaatgg ggcatatgtt gatcaagcga
    29701 catccaaagg acaatttttc aggaaactgt cccttccacc aagattgttt agaggggatg
    29761 gcagcaggac cagcgattga aaaacggttg ggtgtaaaag gccagaattt attggctgac
    29821 gattcgtttt ggcagattga agccttttac cttgcccaat gtgcatacaa tacaacactg
    29881 atgttttcgc cagatagaat tatttttggc ggtggtgtaa tgaaacaaga acacatgaag
    29941 aaaaaagttc aggataaatt tgttgagctt ataaatggat atgttgaaat accaccaatt
    30001 gatagctaca ttattacgcc cgaattaggt gataatgccg gaataatcgg cggattagca
    30061 ttggccagaa aagcggtaag aaataagcaa ccataattaa tgaatgtttc attgatactc
    30121 atgtcaaaag tatttaaccg agtaatcaaa tgatcaaatg aagttggata aagcgaaaat
    30181 gaattcaaat aaaaaggctc taagtcaaat cgtgttgttt tcattaaatc actgaaagga
    30241 aatgcttctg cgtttccttt tttctttttg ttgtgcgctg tataccttga ggatattcac
    30301 tggtggcgta cacttaaata gtaatatatt gtgttacttt atgtctgtgg taatagttat
    30361 agttgcttac caatgtatgt tcatttttcg aaatgttgac ttcataatcc ttggcttaat
    30421 gtttgaattt ttttggtgat agattttttc agccgtataa aataaatcgt aattctatta
    30481 tagagagttg tg
//
LOCUS       DAFLWC010000027        29856 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.027, whole genome shotgun sequence.
ACCESSION   DAFLWC010000027 DAFLWC010000000
VERSION     DAFLWC010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29856
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.027"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            211..1080
                     /locus_tag="L1V17_001116"
     CDS             211..1080
                     /locus_tag="L1V17_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HBN1235899.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            1289..2314
                     /locus_tag="L1V17_001117"
     CDS             1289..2314
                     /locus_tag="L1V17_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBN1235900.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            2353..3303
                     /gene="manA"
                     /locus_tag="L1V17_001118"
     CDS             2353..3303
                     /gene="manA"
                     /locus_tag="L1V17_001118"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HBN1235901.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            3397..5100
                     /locus_tag="L1V17_001119"
     CDS             3397..5100
                     /locus_tag="L1V17_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1235902.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            5102..7135
                     /locus_tag="L1V17_001120"
     CDS             5102..7135
                     /locus_tag="L1V17_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBN1235903.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            7146..7586
                     /locus_tag="L1V17_001121"
     CDS             7146..7586
                     /locus_tag="L1V17_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1235904.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(7786..8913)
                     /locus_tag="L1V17_001122"
     CDS             complement(7786..8913)
                     /locus_tag="L1V17_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1235905.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLLDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(8916..9593)
                     /locus_tag="L1V17_001123"
     CDS             complement(8916..9593)
                     /locus_tag="L1V17_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1235906.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            9857..11623
                     /locus_tag="L1V17_001124"
     CDS             9857..11623
                     /locus_tag="L1V17_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HBN1235907.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            11638..12075
                     /locus_tag="L1V17_001125"
     CDS             11638..12075
                     /locus_tag="L1V17_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1235908.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            12088..13239
                     /locus_tag="L1V17_001126"
     CDS             12088..13239
                     /locus_tag="L1V17_001126"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBN1235909.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(13301..13999)
                     /locus_tag="L1V17_001127"
     CDS             complement(13301..13999)
                     /locus_tag="L1V17_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HBN1235910.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(13992..15344)
                     /locus_tag="L1V17_001128"
     CDS             complement(13992..15344)
                     /locus_tag="L1V17_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HBN1235911.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(15567..16967)
                     /locus_tag="L1V17_001129"
     CDS             complement(15567..16967)
                     /locus_tag="L1V17_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HBN1235912.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            17128..17865
                     /locus_tag="L1V17_001130"
     CDS             17128..17865
                     /locus_tag="L1V17_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HBN1235913.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            17990..18469
                     /locus_tag="L1V17_001131"
     CDS             17990..18469
                     /locus_tag="L1V17_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HBN1235914.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            18466..19233
                     /locus_tag="L1V17_001132"
     CDS             18466..19233
                     /locus_tag="L1V17_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235915.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            19463..20032
                     /gene="lepB"
                     /locus_tag="L1V17_001133"
     CDS             19463..20032
                     /gene="lepB"
                     /locus_tag="L1V17_001133"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBN1235916.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(20136..20738)
                     /locus_tag="L1V17_001134"
     CDS             complement(20136..20738)
                     /locus_tag="L1V17_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBN1235917.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            20844..21313
                     /locus_tag="L1V17_001135"
                     /pseudo
     CDS             20844..21313
                     /locus_tag="L1V17_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            21419..22003
                     /locus_tag="L1V17_001136"
     CDS             21419..22003
                     /locus_tag="L1V17_001136"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBN1235918.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            22006..23079
                     /gene="prfA"
                     /locus_tag="L1V17_001137"
     CDS             22006..23079
                     /gene="prfA"
                     /locus_tag="L1V17_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBN1235919.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            23072..23911
                     /gene="prmC"
                     /locus_tag="L1V17_001138"
     CDS             23072..23911
                     /gene="prmC"
                     /locus_tag="L1V17_001138"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBN1235920.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            23904..24083
                     /locus_tag="L1V17_001139"
     CDS             23904..24083
                     /locus_tag="L1V17_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235921.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            24105..25130
                     /locus_tag="L1V17_001140"
     CDS             24105..25130
                     /locus_tag="L1V17_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBN1235922.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            25321..26565
                     /locus_tag="L1V17_001141"
     CDS             25321..26565
                     /locus_tag="L1V17_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBN1235923.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            26718..27665
                     /locus_tag="L1V17_001142"
     CDS             26718..27665
                     /locus_tag="L1V17_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1235924.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            27799..28428
                     /gene="upp"
                     /locus_tag="L1V17_001143"
     CDS             27799..28428
                     /gene="upp"
                     /locus_tag="L1V17_001143"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBN1235925.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(28567..28809)
                     /locus_tag="L1V17_001144"
     CDS             complement(28567..28809)
                     /locus_tag="L1V17_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235926.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            28930..29002
                     /locus_tag="L1V17_001145"
     tRNA            28930..29002
                     /locus_tag="L1V17_001145"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:28963..28965,aa:Thr,seq:cgt)
     gene            complement(29121..29759)
                     /locus_tag="L1V17_001146"
     CDS             complement(29121..29759)
                     /locus_tag="L1V17_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBN1235927.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
BASE COUNT        10155 a         5259 c         6076 g         8366 t
ORIGIN      
        1 gaggagctat ttttgtttgg ctgttcttat tacttgatgc agaacagctt tttcacaacc
       61 tctttttata agagttttta ctcattaatt tacaaaaaac aagcaaaatg cgaattttct
      121 cacatttttt ttaacaaaat caaagttatt gcttgaaaga agaagaatcc atcgttaaaa
      181 taaagcttga cgtagagggg agcaagaaat atgaaagatt ttcaattggg ggctgccacc
      241 tatttaaaaa gtgtagccat tcgggtgaaa gaccgagata aaatgattga tttttacaag
      301 aacgttgttg gctttgattt gaaaagagaa gaaaacgaat tagccatttt aggaacagaa
      361 gaagctggaa gtgaaatgtt gctgctggaa gaaagtccta gagcgaatga tcacatgggg
      421 gtgatcaaaa agctgaaccg tttttcattg attatcccta gcacagaaga aatggcagat
      481 atcctttgtc gtatccgtaa aatgaattat ccaatcaaag aagctttaga agatcatgga
      541 cgtatgggga ttttgctcgt agacccagaa gagaatgaat tggaaattta ccatgaagag
      601 aataagaacg accaaagaga aattccagaa acaatggatc aagaagcatt attaagaaaa
      661 tctgaagaaa aattcagtaa actatcaaca ggttcttatt ttgaaaaaat ccatttaaat
      721 gttactaact taacaaaaga acgccaattt cttaatcatg tacttggttt gaaggtacat
      781 aatgaagaag agggcatcca tgtattgaat gaaggagatt tccatgttgg tttgacagaa
      841 gctagcggag gcgcaattga tttgcctaca gatgaagtga ttggacttga ttttctgaaa
      901 ttcatgatcg atactgaaag catggaagga ctgattgctc acttgcagca actatcagtt
      961 gatttcttct tagacaaaaa gcacacagta ctcacaatct atgatgctat aggaatcgaa
     1021 tggtggttcg tcagtgagcc aaaagaaaag aataaaactg acattcgatg cgacgcttaa
     1081 ctttttcttt cttaacgatt gtcgcatgtc tcgtcatttt atgaacggtc atactatcgc
     1141 ttattctaga gatagaaaga gaaaatagta taccggggga aactgcgcgg tttttcgcgc
     1201 agtttttttg tgtaaaaaag gttgattcct catagattaa gctttaagct tggactgtaa
     1261 gaatctgata gaaaagcagg agaaaaagat gtatccacac acgaaacagc ttattttgaa
     1321 aaagatggaa gaaggatttt atccaggtgt agcagtcgcc ttcataaaag aaaatcaagt
     1381 agaaacattt acagccggct ttgcccaagt cgttcctgaa aagcagctga tgacagaaga
     1441 tctgttgttt gatgcagcct cactgacgaa agtcgttgca accacttcat tagttttacg
     1501 tctattagaa gatggaaaga tagaactcga tcaaccgctt cataaatatc ttcctgaatt
     1561 tgaaaatcag acaatcactt tgcgtcattt actgacacat acttctgata tcaaaacatg
     1621 gataccaaac agagataagc tatctcagga agaattgatc gccgcttatt tgaagctaga
     1681 accaggtgag caactaggaa aagaagtaaa atatacagat gccggtacga ttcttcttgg
     1741 gttgatgcta gaggaaattt accaagaaac tgcagtggaa atctttcaag aacaagtatt
     1801 ggaaccatta ggaatgatga acagcttatt tcttcctttt ccttccaaaa aaatcgttcc
     1861 cacagaacaa ctgccttcgg gtgaggtttt gcgtggacaa actcatgatc cgaaagcaag
     1921 agttttggct gaacatgcag gtaacgcggg tctctttatt gatttgaaag acagcattac
     1981 ttttgtccaa atgtatttga acaagggaaa aatccgtaat ggtcgttttt tagaagaaga
     2041 gacgattgat tctttactgc aagatcaaac accgaaaaaa aatggctatc gttctttagg
     2101 atgggactta aaaaaggatg tagaagacgg tcatgcgatt ctttttcata ctggttatac
     2161 aggtacgttt ttcttgattg atataaaaac acaagaagcg ttgatatttt tgtcaaatcg
     2221 cgtacatcct gtcgatcatc gtgcggagta tctcatatgt cgagatgaaa ttgttgaaaa
     2281 ctttttgaaa gagaaagcgg tattaccgaa ataatgctat aatagctatg aaaaatgaga
     2341 ggagtttgaa ttatgcagga acctatgttt ttaaaaccag tttttcaaga aaaaatttgg
     2401 ggaggaagtc gtttacgttc agtctttggt tttgatatcc ctaacgataa aatcggagaa
     2461 gattgggcga tcagtgcgca tcctcatggt gtcagtgtag tagaaaatgg cgaattcaaa
     2521 gggaaaagat tagatgaact atggtcagaa cacaaggaat tgtttggcca tccttcagaa
     2581 ccagtgtttc cattattgat caagatctta gacgcagaag atgatctatc tgtacaagta
     2641 catccagatg atgcctatgg gatgaaacat gaaggtgaat taggaaaaac tgaatgctgg
     2701 tatatcatcg atgctgaacc tggtgcagaa atcatctatg gtcatcatgc aaagacaaga
     2761 gaagaactag ctgagatgat caaagatggg cgctgggatg accttttgaa gaaagtacca
     2821 gttaaaaaag gtgatttctt ttatgtacca agcggaacga tccatgctat tggtaaagga
     2881 atcatgattt tagaaacaca gcaaagttct gacacgactt accgcgtgta tgactacgac
     2941 agaaaagatg cgcaaggaca aacaagagag ctgcatatcc aacaatcgat cgatgtaaca
     3001 actgtccctg cgaaaacacc agaattacaa atcaaagaag tccgaaaagg gaattcatcg
     3061 atcgtcactt atttagaaac tgagtttttc aatgtatatg agtgggatat taaaggaatc
     3121 acatctttca aaaaacaagc cccttataca ttgatgacgg taatcgaagg agcaggagac
     3181 cttgtcgttg acggaaaaac atatccatta gaaaaaggaa caagctgtat tattccaaat
     3241 ggcgtttctg agtgggcggt ccaaggtgaa ctagcaatca ttgcgtctga accaggcaaa
     3301 tagttcccag atagctgaaa gcagcagacg gtttttcgtt tgctgctttt tctacataaa
     3361 atccgtccat caataaatag aagtctggtg aaaaagatgg aatacaaatg gaaagcaaac
     3421 aacagcagtc gcgtgtctat gaaacaactg agaaaagctg gacatcactt aaatgaaatg
     3481 atcatgccaa atctaagtct gtttatcgct tggggaatct tgtcattagc aacaaaaggt
     3541 gtgtctggcg atttgcacac cacattagaa gaggtatgcc attggatgat ccagctgctt
     3601 ttacccatct tgatcagtta ttcaggcggg aaatcggtag ggggacaaaa aggggcagtc
     3661 gccggtgcaa ttgcttcttt agggttgatc gctcgttcca atgctccaca aatcgtagga
     3721 gcgatgatta tcgggccgct tgccggcatc gtatatgaac aatttgtttc tagattccat
     3781 gtgaaattca aggctggata tgaaatgctt gtcagcaacc tactagtagg actgactggt
     3841 agcgttattt gtataattgg aatcgttttt attgaaccag ttttaaatag tgttcacttg
     3901 ttgctcgcct ccgttgtgtc ttggctagtc acaatgaatc tgttaccact tgtcagtctg
     3961 atcttagaac ctctaaaagt actatttttc aataatgcaa tcaatcatgg tgtattgaca
     4021 cctttaggaa tcgaattctc acaaacagtc gggtactctt ccttattttt gatggaggca
     4081 aatcctggac ctggtttagg gatcttactt tctatccttt gttttgcaga aaaacaggaa
     4141 aaagtaaatg cgagtggagc attgatgatc catgcgattg gcgggattca cgaaatctat
     4201 tttccatttg tcttgctgcg accgtatcta tttttagctg taatggctgg tggggcaagc
     4261 ggcacgttga tatttcaatg gttagatacg ggattagctg cacctgtatc gcctgggtca
     4321 ctactcgtga tttttgccaa tgcgccttat ccacaactag ctggggtaag tatagggata
     4381 gcaatcagta catttgtgac cttcatttgt gcagcgatac tattgaaatt accaaataaa
     4441 gaaaaagaga acaaaacggt caaagaaagg ggagaaatct tggaaccatc tatcattcat
     4501 tccgtcattt ttgcttgcga ctcaggtatg ggatcaagtg ctatgggagc cgccctgctg
     4561 aaaaagaaat tagcagcaga aaaaatcgat ctttctgtcg gatacagctc tatctatgaa
     4621 ttgaataacc aagtaaatca gctggttatc gtgcaacatg aactagcggg tcttgcaaga
     4681 gaaaaagtac ctcaaagtca aatctatgta ctggatcact ttttggaaac agatatcttg
     4741 ctgtcacgaa taaaagaagc gatccaattt ccaaagcggg aagaaaaaaa agagatagca
     4801 gatatcacag aacaaaaaac gtcgcctgct aatattgtat ttttgtataa aaacaacaga
     4861 cgcggctcac aaactatggg catgacgatt ttaagtcaat tagcaaaaaa agcgaaaaaa
     4921 cagtttgtta tctcaaaaga atcaatagaa aaaatcaaaa tccaagaaga aacgatttat
     4981 atcgcacaaa gagaactagc tgtaactgaa cagctagaag aaaagatccc tcggctagtt
     5041 ctagttgaac attgggtagc tacgaatgaa tacgaaaaac tcgtgaaggg agaaatataa
     5101 gatgtattta tcgcccagag aaaaacaatt attagcagaa tttctcagta gcccgtcacc
     5161 tgtatctatc caaaaaatga tgaatttatt gaaggtcagt aaacggacta tttaccgcga
     5221 attagataat cttgaagtct cattgaaatc ggtaaatgct tctttgaaaa aagcagctag
     5281 aggctcattt gtcattgagg catcagaaga agtattagag caattaaaag aaaatacaga
     5341 tgggaaaagt aatgacttat ccactgctaa acgacaacac gcgattttag ccgagttgtt
     5401 actgacgaca gagccgttga gtcttgctca tttcatggaa tcatatcgca tcagtaatac
     5461 cactttttat gcagatatca aacagttgga agaaagtatt cgccaactgc ctttggaaat
     5521 cattcggaac cagggatacg agatcgaagg accggaaaaa taccgccggc ttctgacagc
     5581 gaatgtatta gaattagaaa tcaatgaata tgaacttttt catagtattt ctttcgatgc
     5641 atcactgaat tatttttttc gattcgttga tccgcaacat ctatctcttg cacgcaaagt
     5701 aatcggggaa gaattgatcc aaaaaaagac caatctaagt gatagaaagc ttgaacattt
     5761 ggttttgatg ctgacattga cgatggagcg tgtgacgaaa aatcatttac tgacaaatga
     5821 gacatataat agtctggcaa acaaagaatt actacagaca gctaaacgat tgttttcacg
     5881 gatcgcttct gagacaaaac aactttatcc agtaaatgag atcgtctttt ttgcaggatt
     5941 attaaatgac ttcacgaact catttgatca gaatttcttt gaagagacgt tcgatacaca
     6001 gcttgcttat ttagtaaaac aactgattca agaagtaagt gaagagacga atgtccattt
     6061 ttatgaagat gaaactttgt acaaaatgct gttgactcat ttatctggtg tgttttcaag
     6121 agccgtttta caagaagaga cactgaccaa tccgatttta gaaaaaatca tggttcaata
     6181 cgaggaagtt gcgaatgcaa tccgtaaagc agtagagcgg atttttcaag aaaaaaaatt
     6241 atccgaagaa gagatcgctt atatggtcct tcattttgcg aattcattgg aacgaagtcc
     6301 gaaagaaagc aatatcagta ttgcaggatt ttcgccaagt ggattagctt ctactagcat
     6361 gttggaacta cgattgaaaa ggtattttcc cttcatccaa caaattcatt tctatcggat
     6421 tgctgattta aaaaaaatcg atttacaaga agaatatgat gttgttattt ctacatctat
     6481 tttaccagga tacggtggaa aatatatttt agtctccccg ctactgctag aagatgaagt
     6541 caagcagcta aaagaagctt tttcgcatat tgagaagaaa aaaaggcaaa aaattacgta
     6601 taacagcaat aacgagtgga tgatagaaga tacttatgag gaaacaatgc atttcatgga
     6661 tcaaatcaat caattactcg gtcgtttttt tatccaagaa ctggataatc ctgagacgat
     6721 ttccgaaacg attcgcagct tatttcctta ttttcctgaa ggactagtaa cggatgaaga
     6781 ggtggttcat cgccggctgc ttaagcgata tgaacaagca cctatcggta ttcctcatac
     6841 aaatatgggg ttattccata catccagctc attgatttct aaaccgatct tttgtatttt
     6901 caatttgaaa catccgttga ccattgaagg gatggataga cagccagtcg atttgtcccg
     6961 tatgttagtt atgctggcgc cttcgccaat ccaagaaaaa gacgggattc ttttaggaaa
     7021 gatcagtgga gcaatcatca tgaatgactt gaacaccgag atcttccgct caggaaataa
     7081 agaaatcgtt tatcagttgt tagcgaaaat cctgattgaa gaaataaaga aatgaaggtg
     7141 aaaagatgat acagctacca gcagaaaaaa tattgctcga tcaatcctat caaaattgga
     7201 aagaagcgtt gaccgagatc ggccagtgga tgacccaaca agggggaatc aaaccggcat
     7261 atatccaatc aatgatcgaa agacaagaaa aagcgagtgt ctatatcggg aatttcgtag
     7321 ccttgccaca tgggactgac aaagatgaag aagtagtaga agaaggaatc tatttagtcc
     7381 aagtgcctga tggtgtggac tttggaacaa aagaggaacc aaaaatcgcg acactcttat
     7441 ttgtagtggc tttaaaaaaa gaacatcagt tagcggtgct ccaagattta gcctttttct
     7501 gttcagacat cgaccaagta atggcgctca gtgatgcgga aaccattgaa gaagtccaaa
     7561 tgatttttga acatggacat atataaccaa tgttcacagt aaaaaaagct gccttgcatc
     7621 aagtaataac ttcaaccaag ataaaaataa gaggagctat ttttgttggg aggttcttat
     7681 tactgcggat gcaagctttt gaaaactatt tattctagaa aaccgtttat ttgaaatagg
     7741 ggacggtgac aaggtttttg tcaccgcccc tattattttt gtgttttaat agctcttttt
     7801 tatatagata gtgcccatac ctatgaataa taaaacgata ctccatatac caagtgtcaa
     7861 gataccattc atgaaagtaa cctgttctga agctagtggc gagaaaatat ctcctcctat
     7921 gatcacattt tgaaaatcaa cataagaagt tggcaagtaa tgactgattg attctatcca
     7981 tccaatcgaa gaaaacaagc gatactctgc taagaaaaga caaagaagtg tacctaaaag
     8041 attgactaga gaatgttcaa ataaagcaga tagaagaaaa ctgattgtac ttaaaaagag
     8101 cacccacaac aacaggaaca gaaagctctg gaaaagatac tcatacatcg gcaggattcg
     8161 tatctcctga ccaatgatcg ttcctacagg ataacggaag tctcccaaac catttttgat
     8221 tattactagt atagagacga tcaaaaatgg catcacgaga cttagcatag ctgcaccata
     8281 ataaatggta aaacggatgc tatgtttctt taccatacta tccagtaata gattgactag
     8341 agagattacc tgctttcttt tttcataaga gatgatggaa gaaagaaaca aggcggttat
     8401 acataaaatc aaaaaactag aaatcattcc tgaaaaaata ttttcgtagt aatttgctaa
     8461 agagagatgc gctggcaagt caaaaataga atatctttgg atctgatgtt ctttcatata
     8521 acggagcaac tcgacacgtt tttgttgttc aatgattgga attccttgtc tttgaccaga
     8581 aatcagtcga tccagtatat ctttttcata atgataagtt gcttcgacca tttgctggac
     8641 attccctgtg ttttttgcat gtaagattgc ttcgatcagt ttgttgcttt tctctaaact
     8701 ttccacaaat tctttctcat tctcatcttc tttcaacgtt tcaatcaaac gttgcatctc
     8761 ttcatagtta tgattcagtt catcgaattc tgtataagca agtttatgat caaaaaaaag
     8821 tgggaatgca aagagcacga ccaacaatag aggaaataaa aagtttactt tgttttttag
     8881 taagagattg cgttcaaatg taagtaaaga catagttaca cctcatataa tttacgataa
     8941 atagctaaaa tctcttccat atttgaggat tctgtgacga tttctccatt ttttagaaaa
     9001 catgctttag aacaaatcga ttggatattc gcgatagcgt gggaagaaag aagaatcgtc
     9061 ttcccctctt tctgccattg tctgatgagg ctattcaaga tatcaatact tcctgggtct
     9121 aatccgttca acggttcatc gaataacatg acagatgaat cactgatcaa gtaagcagca
     9181 agcaagacat gttgtttcat tcctagagac atttttccaa tcggcaaagt aaggtactca
     9241 gtcatcttca atcgttggaa aacagtttgg cattctactt tgctctgcca atagtatttg
     9301 atcaaagtca aataatcaac agccgataga tagtcggata actgattcgt tgattctaga
     9361 aaaaagaaag accggcgata atctgtataa gcagtaggag agatgttgtg aagggacaat
     9421 tgatcataag ttgttggcag cagttgggca atgccattca gcaaagttgt tttgccaaat
     9481 ccgttcgggg caatcaaagc agctacttct cctgattcta ctaaaagatt caattgtcga
     9541 atcacacgtt ttttaccacg tttcatgttc atgtttttga tcagtaatgt catagatagg
     9601 cctccaatat aaaatttaat aacataatag aatggaaaac atctaaatta aatgctaaca
     9661 aaagttattg tttgcatatt ataaaaaaat taaaataaca gttttattta aaattgaagt
     9721 tttctgatac cgaaatcttt ttattttgct gacatactca aacctttggc acaaagtttc
     9781 gtgccaaagt acgactattt ctctttttag taagcggata caattagagt atcaaaagga
     9841 gagagggaga gacaaaatgg aacggacgat tcccaaaaac aacatttcgc taaaagcgag
     9901 ggtacaaaaa ttaggcagta ctttatcaag catggtcatg ccaaatattg gagcactgat
     9961 tgcctggggt gtattaacgg ctctatttat cccagatggt tatttaccaa atgaggcttt
    10021 cgctaccatg gtaagcccaa tgctaactta tctgattcct ttattgatcg gttatactgg
    10081 cggaaaagta attgctggtg accgcggatc agttgttggg gcaattgcaa cgatgggtgt
    10141 gattgtcgga acagatattc caatgatgct aggcgcgatg atcatgggac ctcttggtgg
    10201 atatgccatc aagaaatttg atcagctatt ccaaaaacgg atcaaatccg gttttgaaat
    10261 gctagtcaat aatttttcag caggtcttat cggttttgga ttagcgttat taggtttttc
    10321 tgcgattggt ccagttgtcg atgcattgac tcaagcaatg gcaaaaggtg tagagatcat
    10381 tttatctgcc catttgattc cattgacaag tatttttatt gaaccagcaa aaatcttatt
    10441 tttgaataat gcaatcaatc atgggatttt gacaccattg ggaactgaac aagtagcaga
    10501 ggctggaaaa tctattctat tcttgcttga agcaaatcct ggtccaggac ttggcgtatt
    10561 acttgctttt actttgtttg gcaaaggagc agcaaaatct tcagcaccag gagccatgat
    10621 cattcacttt ttaggcggga tccatgaaat ctattttcct tacgttatga tgaaaccgtt
    10681 attattctta tcagttatag gcggaggaat gtcaggaagt ttcattttcc aattgatgga
    10741 tgctggacta agagcgccag cttctccagg gtcgatcatt gcgattctag cgatgacacc
    10801 gttcaattct taccttcctg ttattttggg cgtgattgtt gccgcagctg tttcgtttgg
    10861 tatttctgca gtaattttga aagcggatgc gaaagataca aatgaagact tcgaaaaatc
    10921 tgttcaagag acaaaggcag ctaagcaagc ttccaaaggt gcccaaggta ttcctcaagg
    10981 agctacattc tctggcgtac aaaaaatcat ttttgcttgt gatgcaggaa tgggatcaag
    11041 tgcgatgggc gcttcgatct tgagaaaaaa agtacaggaa gcagacttgc ctcaaacggt
    11101 gaccaatcaa gcaatcagcc aactgacaga tgactcgaat acattgatcg ttactcaggt
    11161 cgaactacaa gaaagagcaa aacaaaaagc accgagcgcg cgttttgtct cagtagaaaa
    11221 ctttttgaat tcacctcgat atgatgaaat cattcaagaa ttaagcagca agcagaaaac
    11281 atcagtttct gaaattgaga atgagccagc agaagagttt ctttcagcaa acatcaaaca
    11341 aatcaaagag attctacttg tccacgatga tcgttccgga tcagcaacaa tggggatgac
    11401 cgtgctcaaa gatatattag acaagaacca tttaactatc ccgttaagaa aagtcaatat
    11461 ccaagattta aaagatgaac ctgattcact gatcgtagcc aaagaaagtt tagcggaaaa
    11521 agtacagatg gctgcacctc aatccattca tttatcagtc aacagcatgg tcaatccgca
    11581 aaaatacgaa tcgattgcac aatatttgaa acagacagct taagggagga aaacagcatg
    11641 caaagtttgc cattcgacat gatcgagctc aatcgatctt ttaaaaccaa agaagaagcg
    11701 atccgctatt gcggtcagat gcttgtagaa gcagggtgcg ttgatgagga atatatcgat
    11761 gccatggtag atagagacaa aatgttatct gtttatatgg ggaattttat cgcgattcct
    11821 catggaacag atgaagcaaa aaaatatgtg aaaaaatccg gcatctgtgt cgttcaagta
    11881 ccagatggtg tagattttgg taccgaagaa gaagaaaaga ttgcgactgt tttgttcggt
    11941 attgcaggag tcggagatga gcatttgcaa cttgtacagc aaatcgcact ttattgcagt
    12001 gatatggaca atgttgtcca gctagcagac gcgctcagca aagaagaagt aacggaaaat
    12061 ctagcaattg cttaaggaga gagaaaaatg agagcagtac attttggtgc aggaaatatc
    12121 ggtcgaggat ttattggaga ggttttggca gctaatggat ttgagattac tttcgtagat
    12181 gtgaatcaca cgatcattga tgctttaaat gaaagaaaag aatacgaaat cgaattagca
    12241 gatgaatcaa aagaaaaaat cactgtaaaa aatgtcaaag gaatcaacaa tcaaacaaat
    12301 ccagaaaaag taatccaaga aatcgctgaa gcagatttag ttactaccgc cattggcccg
    12361 aatatcttac cttttattgc tgagttgatt gcaaaaggta tccaagaaag agaaaaggaa
    12421 ggaagcacaa catctttaga tatcattgcc tgtgaaaata tgattggcgg ttcagcattt
    12481 ctagaaaaag aagtgtataa atatcttccg gaaacatcat ttactgacaa atatatcggc
    12541 tttccaaatg cagcagtcga tcgaatcgtc ccattacaac accatgaaga tcctttattc
    12601 gtccaagtgg aacctttcaa agaatgggtc attgacgata gccaaagaaa aaataaaaaa
    12661 atccaattaa aaggggtttt atatgtagat gatctagaac catatatcga acgcaaacta
    12721 tttagtgtca atactggtca tgcgactgtc gcttatacag gtgccttgtt aggttaccag
    12781 accattgatg aagcaatgca agatgcgtta gttgtggcac aattaaaatc agttttgcag
    12841 gaaacaggaa gtttgctgat tgccaaatgg gggtttgatg cagagcagca tcatgcgtat
    12901 attgaaaaaa tcattcatcg cttccaaaac aaaaatatct ctgatgcgat cacacgtgtc
    12961 gctcggacac cattacgtaa gttaggttat caagaaagat ttacacgtcc agtgagagaa
    13021 ctacaagaac ataacttgac ttgcccacat ttgacggcaa caatggggat tatttttaat
    13081 tactatgatc ctgaagatga acaaagccgt caattgcatg aaatgaagat ccatgaaaac
    13141 ttggaacaat tgattcaaga agtcacagga atcaatgatc cgaaaacaat cgggaatatc
    13201 aagcaaaacg tgaaccgtta tgccaagcaa gtcgcttaaa ataggatacg aaaaagggga
    13261 atgtgacgaa atttttgtca cattcccctt tttcgaataa ctaggctgtt tgtccttcaa
    13321 gatagggcag atccaattct ttaccgtaac gttgttctaa agctaggcgg atcaaacgag
    13381 ctgccaggtt ctcatttctt gcaaggatag gtccatggaa ataagaaccg aagacatttc
    13441 ggtaaatgac accttcagat tggtcttcac cattatttcc ttgaccttgt accactttcc
    13501 ccaaaggtcg ttcaccttca cctaagaaag tccgaccatt gtggttttca aatccataat
    13561 aagtttcatt gaattcttcg ttatggataa cgatatcacc gataaaccgg ttattttcct
    13621 gacttaacgt gtagtgatcc agtgcactga ttccttggat cttttctcca ttagctccca
    13681 tgtagtagtg acctagcaat tggtagccac cacaaatggc taacatgacg ccatcatttt
    13741 cgatatagtt gatcaaagaa tctttctttt tctggatgtc ttttgaaatg attaattgct
    13801 caaagtcttg accaccgcca aagaaaacca agtcatattt atcagcatca aaaggttcat
    13861 gtatactaac gatctccgta tggcaagaaa cccccatttt ttctgctata tatttcaaca
    13921 tcaaaaggtt tccgttatca ccatatgtgt tcatcaaatt tccataaagg tgggcgatat
    13981 tgagttcata attagccacg gttcattcct cctttgataa atccttgagc agctagttct
    14041 ttacgaagct gcaatacagc agtgtaagta gctaaaatat agacatgctc agttggcaat
    14101 tctttgattt tttcgattac ttctggtaat tcttttgttt ctgtcaattt attttctgga
    14161 atcccggcaa cttttagacg taaagtcata tctgtatgac ggtctcctcc agaaataaca
    14221 gctgggatat ccatatcggc aaagttttca aaattaccat cccaaatcca gctgacatcg
    14281 attccgtctg cgtaattggc atttaataaa gccactaaag aaaatggata aggagctaga
    14341 ccaatcatat cgattacttg attgatacct acaggatttt tgacaagtac taatgtacat
    14401 tttttcccat tgatattgat gacttcttgt cggccgaata ctttctcgtc atatcctaaa
    14461 ccttgtttga ttttatcagg atcgacattg aagtactctg ccactgcagt agctgctaaa
    14521 gcattgtaga cattatacat accgccaact tcgattccgt attcatgacc atcgatcacg
    14581 aaatctgctg acacattgtc catccgtacc atatcagtta atcgataatc caattcagga
    14641 cgtttgaagt cacaatttgg acagtaatat ttccctaagt ttgcataagt gatcatttta
    14701 taatgcaaga tgtgatgaca atttggacat aagacaccgt ctgtattgta atgagccatt
    14761 tgttcacgat cttcttcatg gtcaaagcca taatattttc taggattgac tgtttcgata
    14821 gaattgaaga ttggtgaatc accgttactg ataatcgttg catttggtga ctttgcggca
    14881 ccgtctacaa tcattttata ggtcgtatag atttctccat accgatccat ttgatcacgg
    14941 aaaatatttg taaataagaa cagttctggt ttcatatatt ctgtgacttt gctcaaactt
    15001 gcttcatcta tttctaggac agcaaacttt ttctgtcctt tttttggttt tgcctgcaag
    15061 aaagtcgata caattccctg taccatattc gcaccagtag ggttggttag aacttcatcg
    15121 aattgctggc gcaaaatatt gactgttaaa gcggtagtca atgttttacc gtttgttccg
    15181 gtgacaacga cgacttggta gtcttttgcc aaactatcta gtatatgtgg atcgactttc
    15241 agcgctagtt tacctggtaa acttgatccg cctttaaaaa aagtttttaa tgcccattgc
    15301 gacgtttttc caactgcaat cgcaaaatga ctgcgtattc ccattatgta acctccaaaa
    15361 acgatttgct gacgaataaa ttcaactaat cataccatat gttgaaaaaa aggttaaatt
    15421 gcttttctta ttcttaagaa aaggttacgg ctgaaagtgc atgaaatcgg acaaaatcgc
    15481 atgatttaac aaaaaaacag cttgaaacaa aatgattgtt tcaagctgct gtgattttat
    15541 tattccctct tacctatatt cccattttaa ccgataataa ttttctcgct tggatattca
    15601 tagcctagat ctcgtgtttc ttttggcacg aataacatca atgtatatag cattccgatc
    15661 cgcccaataa acatcagtgt agcaatcgtg attttgccca caacagacaa gtctccggta
    15721 atccctaaag ataaaccagt tgttccaaac gcagaagtta cttcgatgat gatcgagatc
    15781 agcgtttgtt cttctgtagc agataaaaaa acgatacaaa agaaacacat accaagagaa
    15841 agcataaaga caacgactga ttttcgcaca tcatcttgat cgattctccg tccaaaaata
    15901 ttgatgttat cttcactttt gaggaaggaa tatagataca aaccgatgat tgctacagta
    15961 gttgttcgaa tcccgccgcc tacagaacta ggactgcatc cgataaacat cagtaaagaa
    16021 aaaatgatca gtgttgtgat ttgaaaatca cccaaatcgt gaatctgcag accagcatta
    16081 cgagtcgtaa tcgaataaaa catcgaattg atccatttga cactcatatt ggaatcttgg
    16141 aataaatggt ccttttccaa tagataaatc aagacagttc ccgaaacaaa caagataaca
    16201 aaagctaaca cagctaattt ggtaaacaag gaaaaacgaa acggaagctt cgcattggaa
    16261 cgtttgtata atagccattc ccggcactcc atcaatacag gaaaaccaat tcctccgaca
    16321 aaaatcaaaa acatgatcag gatcaagaaa aaatagtcat gtgcaaaggg cttgatggaa
    16381 tccccagtga cgtcaaaccc agagttcgtg acagccgata tcgcctgata aaaaccgtaa
    16441 aaaacggcat cacgccaacg atcaaaatag cctctgtaat aaaaataaat agaaaagaat
    16501 gtcccaaaaa gtaattgaaa ccagattaaa atagcaaaag tgatccgaat cagtcggacg
    16561 ataccagaca aacgcggttg attcatatcc gtcatgatca gctgtcgctg tttcagtgtg
    16621 atccgtcgtt tagaaaaaat gacaaaagca gtagaaatca tcatgatccc caaaccacca
    16681 acttgaaata atatttccag cagtataata ccgttatcat tgaacacaga attgatatca
    16741 aaagtcgata gtccagtcac actcactgta ctgattgcca tgaacagcat gtccacaaaa
    16801 gaaacatggc tatctggttc gcgaaaaatc ggcatataaa atagaacgag tgataagacc
    16861 gtcatcaata tataataaaa aacgatgatt tggatcgatg agaaatgatt ggcagcaaac
    16921 ttctgtcctc gccgctgcag ccttcgaaag aataaatcaa catgcacagt actatcctcc
    16981 tgacaatagt cgtttctacc agtatacaag gggaattagg aatactcaaa gaaattatca
    17041 aacagataac aatacagctt tcgattaaaa tagaaatggc ttataataag gaaaatccta
    17101 gaaaaaagaa ggaggaggaa taacaaattg attaatgctc aacaaatcgt agaaaaaatg
    17161 aaaaatcaaa aaataaatta tgatacagtt ctgaaaaaaa tgatcatgca atgggagaaa
    17221 gaagaagtaa agcctaagat attaatacat acatgctgtg ctccttgcag tacgcacaca
    17281 ttggaattca tgtctcaata tgcagagatc acgttatttt tttcaaattc gaatattcat
    17341 cctaaaagtg agtatttgcg aagattacat gaacaaaaac gatttgtaga ccaatttaat
    17401 gagaaaactg accatcatgt tgcgctaatc gttgatgaat accgtccaaa tgaattcacc
    17461 aaaatggttt taacaaacca tcttgaaaac gaaaaagaag gtggtgctcg ctgcagtgca
    17521 tgcttcaata tgcgattaga tcttgttgcg caaaaagcgc aagaactagg atacgattac
    17581 tttggaagtg ccctgaccat ctcgccaaag aaaaatgcag ctttgatcaa tcagatcgga
    17641 atggatatcc aaaagattta cgggacacaa tacttgccaa gtgatttcaa gaaaaacaaa
    17701 ggctatgaac gctctttgca aatgtgcaaa gagtatgata tttatcgcca atgttattgt
    17761 ggttgcgtgt tcgctgccaa gcagcaagga tgcgatctga aagaaatcaa tcgggaagca
    17821 aaagcttact taaaaacatc aaccgtagtt tttgaggaaa attaaagaaa tctttcggaa
    17881 aaacgtaaga aaaaaataaa gaatttatgg tagaaataag gtagactgta taatttgtcc
    17941 gtagtaaagt aaggaaacaa gaataaattt caatgaagga agagataaga tgcgaaaagt
    18001 agcacctatt ttgaagccaa tcgctgtatt aacaatctcg acgattgtcg cgactactac
    18061 aggtattgtg aatagttcca gctaccgtgc accaagttca agttctagta ctgtagaaga
    18121 aacaacacca actacttcag tctcgacatc tgaaccaaca acaacggaaa gtttgaatga
    18181 aaccactacg acaagtacat gggacgatac aacaactagt tcgtcgtatg atgagacata
    18241 tacaactgac agctcaagcg aaacaagtaa tacggtacca gatggcactc catcggattc
    18301 aaccaatcca agtacaagtc cggatacaag tgctagctcc gaaacgatac caagcagtac
    18361 gactgtagat gataacacgc aaaatgatga tgcagcacgt acagcacagc aaaaccaaga
    18421 ttcaggaaat acccaaacgt ataaccagca agcaggtgat tctcaatgac atttttacta
    18481 gaccttatca acggggtgca taaattcctt ggctatttag acatcagtcc taaatatctt
    18541 aaccgtggat atacgatttt aagtgtgatt cccacgcttt atttattgag aattgtttat
    18601 ggactttggc aaaaccaaaa ctatcttcaa tttttcttat atggacttgc atttctagtg
    18661 cttgtttatt ttactgtttt aaatgtattt tattactttt tagataaaaa cacgaaagcc
    18721 gatgtcactc agctttttgt gaagtattta cctgatgaag cgttcaacat ccagacagaa
    18781 gaatcgatag ataatggaaa ttcgatcgat aaagtgaata cacaagaggt catggtttct
    18841 tatgacgaag attatcaatt gaaattagcc gagaatatgc ggtatttgat tggaaatggt
    18901 gagatcaaaa caaatgaact cggtcgcatg gatggatttc tggtcgatag aaatacattg
    18961 tatccttatt actatgtcaa gaaaacagga gagaaagagt atgttctaaa tattggacga
    19021 agctactcgg acatggaaaa agtagggacc attcgacttg actcaacaga agacacattg
    19081 gaacctgtcg gattgttcat cgtcggcggt gattttgtca aagacgggtt acgctatcat
    19141 gagccttatc gtctgaaatt gattgcaaaa aaggcacagt cgcaggaaga accagtggtt
    19201 tatagtcgta gccaaagaag aagacattca taatgtgatg aaacgccgtg tatcagtggt
    19261 tgcgataaaa acgtttattc ggaataaggg ggatgtgaca cgtcttttgt cacgttcctt
    19321 ttttatataa cgagaaagat aagacgaaca catcacttat tctttccttt catttataaa
    19381 cattgtagaa taaagaaagt acaacgaagt attgtgaaaa aacgtaataa ataacgagga
    19441 aaatacaagt aggaggtaag ctgtgaaaga atttttgaaa aattggggga ttttgatcct
    19501 tgtattagcg gctattttat tagctagagt gtacgtgttt acaccagtta ctgtaaacgg
    19561 gcattcgatg gaccctacat taagtgatgg acaacgattg atttcatcta agatctcaaa
    19621 ctatgaacga atggatatta ttactacaaa ggaaccgggg gatgaagaac ggatgattgt
    19681 taaacggatc atcggtatgc ctggagatac agtcaagatg gaaaatgacc agttgaccat
    19741 taatggcaaa aagtatgatg aaccttatct ggatgagttc aaaaaagaat tttcagaaga
    19801 taagttacaa ggagaatatg cttatagctc aggattccaa gcacaagcag aaagttcatc
    19861 cacctttacg agtgactttg aatatactgt gccaaaagga aagtatcttg ttctaggcga
    19921 taaccgcttg atttcaaaag acagccgaat gtttgggtta gtcgacaaag atatgatcca
    19981 aggaaaagtt gttttccgtt attggcctct ttcagaaatt aaaatcatgt gatgaaaaaa
    20041 taaaaagaag ctgtgacatg ttttttgtca cagcttcttt ttccgaaaat tccttcttat
    20101 ttcttggagt tgctcacttt ttttgcaatc tcattttaag ctttttggct gatggataag
    20161 aaaagcgaag cgtttttgtt cataaatagc ttttccccac gatggaaggt atgactagta
    20221 gcagagacaa agcccgtttt ttccaatcga ttattcaatt cttcttggct aaagccatta
    20281 tggactttcg gatgactaat ttgttcattc ttgtcaaagt ctacgatgat caattgaccg
    20341 ccaggagcta aaatttcata aagttttgta agaatattct ccgtatcagg aatgtgtaaa
    20401 agtacaagtg atagaaggat gagattagct tggacagcag gaaattcgac agaagcatca
    20461 gcgtggatcg ttcggacatt tttcagatct gctgcttgga tcttttcttc tgccattttc
    20521 agcatagttt ctgaagcatc ggcaatgatc agttctttga atctttccgc aagcggtaaa
    20581 ctaacaagcc cagttccgcc tccgtaatcc agcaggactt tttggtggct gtcgcgcggt
    20641 agataagtag ttagttcttc gcgaataatc ttggctaatg cttgacggtc aggggaatca
    20701 taatggttag cgatggaatc aaaaatattt tttgtcatca aatagctcct tacgtaaaac
    20761 tttgaaattt taacttatta tagcacgtga aaagaaagaa agcatgctat actcaattca
    20821 aaaagggaga atctagaaag aatatgccga tatcgtttgt aaaagataga gaggaaaaag
    20881 gaaagtgtgt ccgagaaata ttactagact tgcctgagtg gtttgggctt cctgaatcaa
    20941 cggaaaaata tatcgaggaa tcaagtaaac tacctttatg gtgtgaaaaa agaaaagaag
    21001 aatatttagg ctttatcact ctttcacaga caagtgaaga tactgccgaa atctattcta
    21061 ttgtatggga ataaaaaaag actatcatca ccaaggatta ggaacaaaac tttttaaaga
    21121 agcagaaggt tacgcagcaa aacattacaa atatttgcaa gtgaagactg tagacgaggg
    21181 gcactactct atatatgatc aaactatttg tttctacgaa tcattaggat tttcaaggtt
    21241 ggaagttttt ccaaatttat gggatgaatg gaacccatgt ttagttcttg tcaaaaaatt
    21301 ggaacaaaag tgagcaatag atttaatact aatctgtgct tgatgaaaat tctcactgta
    21361 aaaaatgctg aaaatcaagt ataataccat aggaacaaac tggaaggtga aaaagagcat
    21421 ggcacaacta ttttttaagt atggcgcaat gaatagcggc aagacgatcg agatcctaaa
    21481 agtcgcacat aattatgaag aacaaaataa gccagttgtc ttaatgacaa gcggtattga
    21541 tacaagagat ggtttaggcg ttgtttcaag ccgaatcgga ctgaaacgta atgcgatgcc
    21601 gatatttgaa gaaacagacg tatttgacgt aattcagaaa atggaaagca aaccctattg
    21661 tgtgctgatc gatgaagcgc aattcttaaa aaagaaacat gtcattgctt ttacgagaat
    21721 tgtggacgaa ttggatattc cggttatggc atttggtttg aaaaatgatt ttcgaaacga
    21781 gttatttgaa ggatcaaaat atttattgct ttatgcagac aaaatcgaag aaatgaaaac
    21841 aatctgttgg ttctgccaca aaaaagcaat catgaattta cattatattg atggaaaccc
    21901 tgtttatgaa ggcgatcaag tgcaaattgg cggaaatgaa gcttattacc ccgtttgtcg
    21961 aaaacattac tttcacccat caatgattac agaaggagaa taagcatgta cgatcaatta
    22021 caagcaattg aagaccgtta tgaagagctt ggagaacttt taagtgaccc agaagtgatt
    22081 tctgatacaa agcgttttat gcagctttca aaagaagaag caaacacgcg cgaaacagtc
    22141 gaagtttatc gtcgttataa agaagtagta caaggaatca ccgatacaga agaactgctt
    22201 ggtgaaaaac tggatgatga aatggctgaa ctagcaaaag aagaattatc tgaattaaaa
    22261 aaagaaaaag aagtcttaga agaaaaaatc aagatcttgc ttttaccaaa agatccaaat
    22321 gacgataaaa atatcatcat ggaaatccgt ggagcagcag gcggagacga agcagcatta
    22381 ttcgctggcg atcttttcaa tatgtaccaa aagtatgctg aagcacaagg ctggaaaaca
    22441 gaagtgatgg aagctaacgt taccggaatc ggtggatata aagaagtgat catgatgatc
    22501 accggagaca acgtatattc gaaattaaaa tatgaaagtg gtgcgcaccg cgtccagcgt
    22561 gttccttcaa ctgaatcgca agggcgtatc catacttcca ccgcaacagt tgtcgtgatg
    22621 ccagaagctg aagaagtaga gatcgatatt gaagacaaag atatccgtac agatatctat
    22681 catgcttcag gtgctggcgg acagcacgtc aataaaacag catctgctgt acgtttgact
    22741 cacttaccaa cagggatcgt tgttgctatg caagatgaac gttctcaaat caagaaccgt
    22801 gaaaaagcaa tgaaaatctt gcgtgctcgt gtgtacgata agatccagca agaagcacaa
    22861 agcgagtatg atgccaatcg aaaatcagca gtcggaactg gggatcgttc agaacggatc
    22921 cggacgtata atttcccgca aaatcgtgtg actgatcatc gtatcggatt aactatccaa
    22981 aaattagatc agattttagc agggaaatta gatgagatcg ttgatgcatt gatcatgtat
    23041 gatcaaacat caaaactgga agctatgcaa aatgggtaaa atgacctatc gagaagtcct
    23101 gtcacgggct tcttcttttt tagaggatca tgggaaagaa gcatatagta tccaattttt
    23161 atttttggaa cgaaaacaat ggaaaaaact tgattggctc cttcatatga acgaagagat
    23221 ttcagaagaa gaacagcggt tgatcgaaac cgatctgcga cttctgcttg cagatcatcc
    23281 acctcagtat ttgctaggat atgcagattt ttatgatcat cggttaaagg taactgaagc
    23341 aacactgatc cctcgaccag aaacagagga gttagtcgaa tggtgtttag acgagacgcc
    23401 tggtgtaccg ttagaagtga tagatattgg gacagggact ggagcaattg ctattagttt
    23461 gaaagcagca agaaaaaatt ggcatatatc tgctgtggat ctttcagaag aagcattaga
    23521 agtagcgaaa gaaaatgctc agaaagaagg aacgaaaatc agtttttatc atggagatac
    23581 attaggacca gtaatggatc agcaatttga tgtgattatt tctaatccgc cgtacatcag
    23641 tcggaatgaa tgggaactga tggatgaaag tgtccggtca ttcgaaccta aaatggccct
    23701 ttttgctgag aacgatggat tagctattta tgaaaaaata gcagttgaag caccaagcgt
    23761 actaaaatca aatggaaaga tttttttaga aatcggattt cgccaaggtg aagcagtaaa
    23821 aaaaatattt cagcaagcat ttccagataa aaaagtggcg ataaaaaagg atctttttgg
    23881 caatgaacga atgatccaag tttatggttg aagttgtgga tgaaaaattt tttatttgtt
    23941 tttttattat aaaaaaacac ttatttgaca aggatgtaaa cgactttttg gtttatcaac
    24001 aagtttatcc actattgaca aatagattat ccacaaacag tggaaaactt gaggataaac
    24061 tcagacaaaa taagaatgta tgaaaaaggg gttgtggata aactgtggaa acgaaacgat
    24121 atgatgaaac agaattgcaa gaggcagccg aagcactgaa agaaggagaa cttgttgctt
    24181 ttcctaccga aacagtatac ggattgggcg ccaacgctct tttaccaaac gctgtcaaga
    24241 aagtgttttc tgtaaaaggg agaccgcaag ataatccatt aatcgtccat gtcgcctctt
    24301 ttgaacaagt aaaagagtat gtggacaact ttcatccggc agcagagaag attgtgaaga
    24361 acttctggcc tggaccatta actttgatat ttaagatcaa aaaagacact ttgccctcag
    24421 ttgtgacggg aggattatcc acagctgcat ttcgtatacc ggataacaaa aaaacactag
    24481 aagtaatcga actttccggt gttccgcttg tcggtccaag tgcaaatacg tcgggaaaac
    24541 caagtccaac gactgcagat catgtatatc atgatctaca aggaaaaatt accgggatta
    24601 ttgatgatgg agctacgcga attggtgtag aatccactgt tcttgattta agtgatccaa
    24661 cagccatgcc tatgatttta cgaccaggtg cagtaacgaa agaacaaatc gaagcagtca
    24721 tcgaatctcc tgttgctatt gatcagcatc ttgtaaaaga aaatgaaaca ccaaaagccc
    24781 ctgggatgaa atacaaacac tactcacccg atacacgtgt tctgatggtc agagatggcg
    24841 attggtcaac tgcagttcaa tgggcaaaaa ataagaagat ccgtgcaggt gtcatagcaa
    24901 gccccgaaat tgcggatcaa gtgcggacag atactgcagc tgtttatatg tataacgaca
    24961 actcagtaga agcggcggct aaaggattgt ttgcaggtct aagaggatta gatgaaccaa
    25021 cacttggatt agatttgatt tttgtacaag tgtatccaga aactggattg gggaatgctt
    25081 acatgaatcg cttgaaaaaa gcagcaggac aaaattattt tgaaaaatga tcaattggtt
    25141 attgtcgcat tcttttagta tgatacaatg ctatcaagta aatcttctat cagtgaacga
    25201 aaaactaagc gtaactaatc gtaatagaag agatacgaat atttggcaat ttgtttttga
    25261 tgggaaaaat aaaattgtag gaaaataaaa ttgtaggaaa ataaaaagga gctgttgttt
    25321 gtggtagatt acaaaacgtt tgaccctgat ctttgggctg cgatcgccaa agaagaagaa
    25381 agacaagaac ataatttgga gctgattgcc tctgaaaact ttgtctccga agcagtgatg
    25441 gctgcacaag gaagtatctt gacaaataaa tacgcagaag gttatccagg gcatcgctat
    25501 tatggtgggt gtgaatttgt cgatatcgtt gaaaatttag cgattgaccg tgcaaaagaa
    25561 ttattcggag cgaaatttgc gaacgtccag cctcactccg gctctcaagc caacacggct
    25621 gcttatctcg ctttggtaga accaggggac acgatcttag gaatggatct ttccgcaggc
    25681 ggacatctaa cacatggatc accagtcaac ttcagtggca aaacctatca ctttgttgct
    25741 tacggtgttg atccgacaac agaagttatt gattataatg tggtacgtat tttagctaga
    25801 aaacatcaac caaaattgat cgtagcaggt gccagtgctt acggacgaac gatcgacttt
    25861 gcgaaattca gagaaatcgc agatgaagta ggcgcaaaac tgatggtaga tatggcacat
    25921 atcgcaggat tagtagcagc aggacttcat cctaatccag ttccttatgc agatatcaca
    25981 acgactacca ctcataaaac attgcgtggc cctcgaggcg gcatgatttt gacaaacgat
    26041 gaagcattag caaaaaaaat aaatagtgcg gtatttcctg gtattcaagg cggccctcta
    26101 gagcatgtga ttgcgggtaa agcagtagca ttcaaagaag cattagatcc tgcatttaaa
    26161 gaatatagtg aacaaatcat cgccaatgca aaagcaatgg tcaaagtttt caatcaagca
    26221 attggaacca gagtcatttc aggggcgaca gataatcatc tgatgttgat cgatgttcgc
    26281 gagttaggta taaatggaaa agaagcagag agcattttgg acagtgtgaa tatcactgta
    26341 aataaaaact cgattccttt tgaaacacta agtccattca aaacaagcgg tattcgaatc
    26401 ggcacgccag caatcactac tcgcgggttc aaagaagaag atgctgtaaa agtggctgaa
    26461 ctagttgtca aagcattaca agcaaaagat gataacgctc aactagacga agtcaaaaca
    26521 ggtgtacgcg aattaactga aaaatttccg ttgcataaaa aataaaaatt taaattccat
    26581 tagtaaacag aaaagttcaa tgttgggctt ttctgtttat tttttgggaa aacggattct
    26641 ttgacaatat cggtgatgct ctctagtata tgaggtgtaa ttttagtctt cacactaaat
    26701 ctcagggagg aaaagtcatg actgatcgta tctcgttaga aaaggaagca gtagcattca
    26761 gtgatgcaaa tgcgcctcat ccgcgtatct atgaactagc accggaagaa ggaagagttt
    26821 tactagaaga agtacaagaa tcacctgtga acaaatattc cgtcgatatt gaagacttga
    26881 tggtggatac tggcgaatgg ggaaaactca atattcgtct cgtacgacca gaagggaata
    26941 tggataaatt accagttatt ttttatattc atggagcagg ctgggttttt ggcagtgctc
    27001 aaacccatga taaattgatc agagaacttg cggttcgtac gaattccgtc gttgtctttc
    27061 cagaatatag tcgatcacca gaagcaaaat atccaacagc aattgaacaa aattatgctg
    27121 tgttgcaaca gctgaataaa ttagccaagt caaaaaatct ggatctcgag aatctaatcg
    27181 ttgcaggaga ttcagtaggt ggtaacatgg ctacagtcat gacgatctta acaaaagaac
    27241 gaaagggcct cccaatatcc aagcaattgc tgtattatcc agtcacaaac gctgattttg
    27301 atacagattc ctatcatgaa ttcggagaaa actatttttt gacaagagaa ggaatgatgt
    27361 ggttttggga ccaatatacg acgaatgaag aagagcgtgc tgaaatcaca gcttcgcctt
    27421 tgagagcaaa tataaatgaa ctaaatgatc ttccttcagc aatgatttta acgggagaag
    27481 cggatgtatt aagagatgaa ggtgaggctt atgcgcgcaa acttcgtgat gcaggggttc
    27541 ctgttacaca agtacgcttc caaggaatca tccatgattt tgtcatggta aatgctatgg
    27601 atcagacaaa ggcaacgcgt gcagcaatgg cattatctac ttcttggatc aagaaaaaag
    27661 aataagcttt gcttgtccgc aggaaaactt cttttcaaaa acggattttc ttaggaaaaa
    27721 tggcgagttt gactagtcaa tcacttgatt ttgttttaca attaaaaaga aacgacagaa
    27781 caaaggagag cttaaaaaat gggcaaattt caagtgatcg atcatccatt gattcaacac
    27841 aaactaacta ttattcggga caaaaactgc ggaacaaagg tttttcgtga agtagtcgat
    27901 gaaatcgcta tgttgatggc atatgaagta tcacgggata tgccattgga agacatcgtg
    27961 atcgaaacac cgatcactga aacaacacaa aaaacgttgt ctggtaaaaa agtagcgatt
    28021 attccaatct tgcgcgcagg tattggaatg gttgacggta tcttggaatt gattccagct
    28081 gctaaagtgg gacatatcgg tctttatcga gatgaagaaa cattggaacc acatgaatat
    28141 ttcgtcaaac ttccagaaga cattgatgca cgtcagttgt ttgtagtaga tccaatgttg
    28201 gcaacaggcg gatcagcaat catggcaatc gatgcattga aagaacgtgg cgcgtcgaac
    28261 attaaatttg tttgtttggt agcagcacct gagggagtaa aagctttgca agaagcgcat
    28321 cctgatattg acatctatac agcttctcta gatgaaaaat tgaatgaaca tggttatatc
    28381 gttcctggac taggggatgc gggtgaccgt ttgtttggta caaaataagt aaatacgaaa
    28441 aagggtgtga cacaactttt gtcacatcct tttttggtca tttttaacgt ttgatgcaga
    28501 acagcttttt cacagctttc gtttgcatat aaaaaaacca tcccaaaaat gcagagatgg
    28561 tcaaattcaa atctttttta gttctttgta gttaacgatt actacaccct tactttgcgt
    28621 catcaagttc gcattttctg cagtttcatc aatctcaaca acagcggaat ttttcaattg
    28681 ctttgaaatc gttccagttt gcgacttgcc gtgaattgtg aacattacgt gagtattgat
    28741 cttgaatttt tcaccaattt ccgatggtac gatagttgta tcaaattttc caaaagttgc
    28801 cattttcata aaacctgcct ttcacatcaa ttataccacg ttttatgaaa aatatcatga
    28861 aattaaacta attttccatc ggactcttta caatcagcca aatagagtat ataatttctt
    28921 ttggataagg ccagcttagc tcagttggta gagcaacgca ctcgtaacgc gtaggtcgta
    28981 ggttcgatcc ctatagctgg cattaaaaga gaagacagat atatcaagga tttttaatcc
    29041 attgatacat ctgtcttttt gtttaaagga aataaagtat gctttcttag caatagagca
    29101 tgtattattt ctataaaaat ttaggagaat aaaacgacta gcaatatagc tgtgaaatca
    29161 aatatcacat gaactgccca acttgtaatg atcgagttgc ttttaatggc agcttggttg
    29221 aataacaatc ttgccacccc ttgtatcaaa aggatgtgtg ctacagtgtg taaaatattt
    29281 ccattatcat aagtactgta atggataaat ccaaagatga ttgctgacaa gaaactagcg
    29341 acaggaatgc tgaacttact agaaaaaata gcgagaaaat acactgagaa caattcttct
    29401 ccaagtatca tgataggcaa aataataaat aataacgggc tgaaagcctc atttattgga
    29461 ttgcctgtta aaccccattt caaaatttgt tgcaaaaata ccgagactgc ggcactgatt
    29521 actacattga taaaaaaata tttggctata tttttgacag gagcgacagg tttcgagaac
    29581 atttttttcg tatctttttt accaaaaaca agtgtaaatg ctataaatcc agtgatagtt
    29641 aaagaaaaaa tgctaataat ggatggcgca aatagcaacc ctaacaaacc gagtacaacg
    29701 acaatagtgc ccaatatccc ttttttaagt tctatttttt ttcctaaaat gttattcatg
    29761 ataataactc ctactattca gtttttgaag atagagtcag tatacatgaa gagttaaaat
    29821 aggcaatgtt tttttatgga tatttgtatt gctaaa
//
LOCUS       DAFLWC010000028        29097 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.028, whole genome shotgun sequence.
ACCESSION   DAFLWC010000028 DAFLWC010000000
VERSION     DAFLWC010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29097
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.028"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..1031)
                     /locus_tag="L1V17_001147"
     CDS             complement(<1..1031)
                     /locus_tag="L1V17_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1235928.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1113..1802)
                     /locus_tag="L1V17_001148"
     CDS             complement(1113..1802)
                     /locus_tag="L1V17_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBN1235929.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="L1V17_001149"
     CDS             complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="L1V17_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBN1235930.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2329..2832)
                     /locus_tag="L1V17_001150"
     CDS             complement(2329..2832)
                     /locus_tag="L1V17_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBN1235931.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3036..3163)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="L1V17_001151"
     CDS             complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="L1V17_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBN1235932.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="L1V17_001152"
     CDS             complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="L1V17_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBN1235933.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4800..5468
                     /gene="sdaAB"
                     /locus_tag="L1V17_001153"
     CDS             4800..5468
                     /gene="sdaAB"
                     /locus_tag="L1V17_001153"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HBN1235934.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5481..6353
                     /gene="sdaAA"
                     /locus_tag="L1V17_001154"
     CDS             5481..6353
                     /gene="sdaAA"
                     /locus_tag="L1V17_001154"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HBN1235935.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6444..7463)
                     /locus_tag="L1V17_001155"
     CDS             complement(6444..7463)
                     /locus_tag="L1V17_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBN1235936.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7636..8541)
                     /locus_tag="L1V17_001156"
     CDS             complement(7636..8541)
                     /locus_tag="L1V17_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBN1235937.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="L1V17_001157"
     CDS             complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="L1V17_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HBN1235938.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9246..9416)
                     /gene="secE"
                     /locus_tag="L1V17_001158"
     CDS             complement(9246..9416)
                     /gene="secE"
                     /locus_tag="L1V17_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBN1235939.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="L1V17_001159"
     CDS             complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="L1V17_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBN1235940.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9754..10398
                     /locus_tag="L1V17_001160"
     CDS             9754..10398
                     /locus_tag="L1V17_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBN1235941.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10454..10957)
                     /locus_tag="L1V17_001161"
     CDS             complement(10454..10957)
                     /locus_tag="L1V17_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBN1235942.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10970..11016)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11554..12519
                     /locus_tag="L1V17_001162"
     CDS             11554..12519
                     /locus_tag="L1V17_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBN1235943.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12618..13790)
                     /locus_tag="L1V17_001163"
     CDS             complement(12618..13790)
                     /locus_tag="L1V17_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1235944.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13777..14922)
                     /locus_tag="L1V17_001164"
     CDS             complement(13777..14922)
                     /locus_tag="L1V17_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1235945.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14936..15868)
                     /locus_tag="L1V17_001165"
     CDS             complement(14936..15868)
                     /locus_tag="L1V17_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1235946.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15985..17064
                     /locus_tag="L1V17_001166"
     CDS             15985..17064
                     /locus_tag="L1V17_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBN1235947.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17061..17679
                     /locus_tag="L1V17_001167"
                     /pseudo
     CDS             17061..17679
                     /locus_tag="L1V17_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            complement(17789..18016)
                     /locus_tag="L1V17_001168"
     CDS             complement(17789..18016)
                     /locus_tag="L1V17_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBN1235948.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18119..20707)
                     /locus_tag="L1V17_001169"
     CDS             complement(18119..20707)
                     /locus_tag="L1V17_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBN1235949.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20727..21386)
                     /locus_tag="L1V17_001170"
     CDS             complement(20727..21386)
                     /locus_tag="L1V17_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBN1235950.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21435..21938)
                     /gene="trmL"
                     /locus_tag="L1V17_001171"
     CDS             complement(21435..21938)
                     /gene="trmL"
                     /locus_tag="L1V17_001171"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBN1235951.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22159..23025)
                     /locus_tag="L1V17_001172"
     CDS             complement(22159..23025)
                     /locus_tag="L1V17_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBN1235952.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23134..23775
                     /locus_tag="L1V17_001173"
     CDS             23134..23775
                     /locus_tag="L1V17_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBN1235953.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23837..25198)
                     /gene="mgtE"
                     /locus_tag="L1V17_001174"
     CDS             complement(23837..25198)
                     /gene="mgtE"
                     /locus_tag="L1V17_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBN1235954.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25216..26115)
                     /locus_tag="L1V17_001175"
     CDS             complement(25216..26115)
                     /locus_tag="L1V17_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBN1235955.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26117..26914)
                     /locus_tag="L1V17_001176"
     CDS             complement(26117..26914)
                     /locus_tag="L1V17_001176"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HBN1235956.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26892..27596)
                     /locus_tag="L1V17_001177"
     CDS             complement(26892..27596)
                     /locus_tag="L1V17_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBN1235957.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27727..28302
                     /locus_tag="L1V17_001178"
     CDS             27727..28302
                     /locus_tag="L1V17_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HBN1235958.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28420..29097
                     /locus_tag="L1V17_001179"
     CDS             28420..29097
                     /locus_tag="L1V17_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBN1235959.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8560 a         6167 c         5232 g         9138 t
ORIGIN      
        1 aatacagtat tatttcggtt gcttgctgct tcacctagcc cttgtactcg tgtttgattg
       61 gcgacttgac caaattgatt cccgacgtct aataaaataa tagctaaaag caaaatggcc
      121 aaatggcttc cgccaaccaa taaagcaata aagcttattg tttgcataac aagtcccata
      181 tacacgattt ttctttcaga ataagaatct gccagtcgtc ccacgatagg tgcagcaact
      241 gctccagaca aaccaaaaat cgctaatatc cctgcttcga atgttcccca attgtaggcg
      301 ggactgctga tataaaaaat caacgtagac caaaagatcg aaaatgttcc aaacatgaaa
      361 aatccactga ctgccgcttc tcttaataga cgttgagaag caactaaatg cggcaaactt
      421 ttaagtgaat caaggtatga aacagctgta ctactttgct ggacagaacg cggcattttc
      481 cagtaaagca gaagtgtaag aattccgact gcacataaag caaataaata gatcatccgc
      541 caagaaaaaa gactggcaac aataccagat accgtccgag aaagcaaaat ccccacgagt
      601 aaaccgctaa gcaatgtacc catgaccttc cctcttgctt ttggtcccgc tagtaccgca
      661 ccgtaaggaa tgatgatttg cggcacgatc gaaagtaatc ctattaaaaa agaagcgcat
      721 gcaaataacg taaacgaagg cgcaaaaaaa gcggccaaca gagagacggc agataacgct
      781 accattcgaa tgatcaattt tggacgatcc accacgtccc ctaaaggaac taaaaacagt
      841 aaccctaacg catagcctaa ttgggtcaac atcgtcaata tcccgactgc acttgtgcta
      901 acagataaac tagctgctac ttttgttcca atcggctgga tgtaatacat attggcaaca
      961 acaacgccac aagtgattga taatagtaaa ataagcgaag ttgttaaagg tgttttttca
     1021 ttactcttca ttgatttccc ccatttccta tcttagttta caacttatgg aaaagattgg
     1081 aaatagaaaa atacaactat tcgccacact tattatttgt gcttttgttt tccttgtttt
     1141 ttcttgcgat ctttataaat gaagacaact aaccctacta gcacagtaac acttgcaacc
     1201 aacgtgactg cagttttgtt atatccgtga aacagagctt ctccaccaca cgcatacaac
     1261 acagacgaag ggatgactcc aatcacgatc gacaatatga tttgctgtag aggcaatttc
     1321 atcgcatctg cagcaaaatt gaccatagaa gatggaataa ccggtatcat atagcctaac
     1381 attacaccta tttttggatg tttcatttgt cggattgctt gcacccaatg attcgtttcg
     1441 gttttcttat ctaaaaattt taagcgatgc ataaggaaaa ttgcagtgat gttaccaaga
     1501 gcattaccca aaatgttgat gatcgcacct gtcagtggtc caaagctcaa accagcaatg
     1561 actccaacta ctgaagtagg aatacctgga acagcacaca tcaccgctgt caatacgatc
     1621 aagagtatcg atgcaaaagt cccatgcgaa cgaatatgtg cgagtagctc tgccttactc
     1681 gctctcggat ttaaaaataa ttggatgtct gtctgatatt ctaaatacaa ccgatagccc
     1741 actaccagta tcagaatgat tcccaacgag atcaacatca atcggattat tttctttttc
     1801 atatttcctc ctgaaaaaaa tctatattca ttaaataata gtttaacata aaaacaaaaa
     1861 agcaccgaaa tccaacatag gatctcagtg cttttaaata gtaaaaatta tttaacagtt
     1921 acagatgcgc caacttcttc aagtttagct ttcaattctt cagcttcttc tttagatacg
     1981 ccttctttaa ctggtgcagg agcgccatca actacagctt tagcttcttt caagcctaaa
     2041 ccagttgctt cacgaactgc tttgataact ttaacttttt ggtctccagc tgcagttaat
     2101 tctacagtga attctgtttg ttcttcagca gcagcagcgc caccagcagc agctacagct
     2161 acaggagcag cagcagatac gccaaattct tcttcaatag ctttaactag gtcgttaagt
     2221 tctaggatag ttgcttcttt taactcagca acgatgtttt caatgttcaa tgccattata
     2281 atttcctccg tttaattgtt cttttttatt taatgcttta tgcggcaatt aagctgcatc
     2341 tccatcttct ttgtctgcca ctgctttgac agcgtaagcc acgttgcgga ctggcgcttg
     2401 tagtacagat agcaacatag atagaagtcc ttcgcgattt ggcaattttg ccaatgctgt
     2461 gatttcttcc aatgaagaga ctttaccttc gatgataccg cctttgattt ctaatgcttt
     2521 tgcttcttta gcaaattcgt ccatgatttt cgctggtgcg actacatctt cgttactgaa
     2581 tgcaacagct gtaggtccag tgaatacttc gtccatgcct tcaaggccag cttttttagc
     2641 tgcacgtgaa agaatagaat ttttgataac tttcatttct acgttagcat cacgaagttg
     2701 tttacgtaaa cgtgttactt catcaactgt taatccgcgg tagtcaacga ctactactga
     2761 tgcagctgct gtaaattttt cgcttacttc atcaacgatt gctgcttttt ttgcgataat
     2821 tgcttcactc atttttgagt ttcacctcct gaattttgat ggaagagttt tttgcactga
     2881 aaaggcaagt cacttttata gttactttgc tcaaccagta ttattcatca cctattcact
     2941 tcgttcatag tgattctact cgctttgctc gaaaggaaac tcctttcgct ttgctcaacc
     3001 agtattgttc atcatctctt cacttcgttc atagtgattc acaataaaaa actctatgcc
     3061 accgcagaca tagagggact attgaatata ttcaataaac gtcctcggta ggaaattaag
     3121 gcttgatgcc acctactgtc ttcggtacaa gttaattatt aacctcaact agcttagcat
     3181 gctaaactag ttgagtcaag aattattttt cagttggatc aatcaacatt ctaatattta
     3241 attagaaaga agcttggtca acatggatac caggtccaaa tgttgttgtg atcgttacat
     3301 ttttcatgta ttgaccttta gctgctgatg gtttagcttt tagcaataca tcatggattg
     3361 ctgcaaagtt ttcaactaat ttttcatcgt caaatgaaac ttttccgatt ggtacatgga
     3421 tatttccagc tttgtccaca cggtaagtta ctttaccagc tttcacttcg tttactgctt
     3481 ttgttacgtc cattgtaact gtaccagttt tagggtttgg cattaagcct tttggtccta
     3541 atactcgtcc tagacgacct acagtagcca tcatatcagg tgttgcaaca actacatcaa
     3601 agtcaaacca tccgttttgg attttttgaa ccatgtcgtc gtcacctacg aaatctgcac
     3661 cagctgcttc agcttctttt gctttgtctc ctttagcaaa aactaaaaca gtttgtgttt
     3721 taccagttcc gtttggtaat acaacagcac cacggatttg ttggtctgct tttttagggt
     3781 ctacgttcaa acggtatgca acttcaactg ttgcatcaaa ttttgcaatg tttgtttctt
     3841 ttgctaaagc tactgcttcg gcaacaggat aaactttact tgaatcaact ttttttaatg
     3901 catcttgcat ttttttgctc tttttagcca ttttggttcc tccttgattg tggttataac
     3961 ggttgtacct cccacgtgtt ctatatcttt caatatagag ccaactgaga agctgctgtc
     4021 ttagggtgta tagattattc tacagtgatc cccatgcttc gtgcagttcc ttcaaccatg
     4081 cgcattgctg cttcaacgtt agctgcgttt aggtcttcca tttttaattc agcgatttct
     4141 cttacttgat cgctagaaac tttcgcaact ttatttttgt ttggttcgcc tgaacctttt
     4201 tcgattttag ctgctttttt caatagaaca gcagctggcg gtgtttttgt aacgaatgtg
     4261 aatgaacggt cttcgtatac agaaataaca accggaatga tcaaacctgc ttgatcagct
     4321 gtacgagcgt tgaattcttt tgtgaatccc atgatattga tacccgcttg acctagtgca
     4381 ggacctactg gtggagctgg agttgcttta cctgcaggaa tttgcaattt aacgattttt
     4441 tctactttct ttgccacgag acatacctcc ttaagtccgt gatgtggtta attggagatg
     4501 catatttctc ctcccacgtt ttatctgatc tgaaaaaatc cagacaaata atgtgcaaaa
     4561 caatgcacac tggtacagta tagcaaattt atttgttttt tcaagatttt tttctgctat
     4621 ttttacattt tgcttgaata aacgctaaat ttattctaaa aaaacaacaa tttttcgttc
     4681 tcatttcttc ttttatgtta cacttgcgct agcatggttc aacagatgaa agcaaacaat
     4741 aacacggttt tttagaccct tgtacaaaga ttcctacata acaaaatgag gtggagaaaa
     4801 tgaaagattt aaggtataga agtgtctttg atattattgg acctgtgatg attggtccaa
     4861 gtagctctca cactgccgga gctgctagaa tcgggaaaat catacgtagt atatttggcg
     4921 aacagcctga ttctgtagat atttatctat atgaatcatt tgcaaaaacc tatcgggggc
     4981 acggaacaga tattgcatta gttggcggcc tgttagggat ggaacccgat gatgaacgtt
     5041 tagctgattc tttgaaattg gcatatgaag ccggtatgga agtcttgttt gttcctaaga
     5101 gtgaaaaagc cgaacatcca aactctgtaa agatgcttct aaaaaaagga acacgaaagc
     5161 tttcagtcac tggcatttcg atcggcggtg gcaatatcca gatttctgaa ttgaatggat
     5221 tcaaaatttc tttaagcatg ggtactccta ccttgatcgt tgtccaccaa gatgttccag
     5281 gtatgattgc taaagtgact agtatacttt ctgagaccaa tacgaatatc ggcactatga
     5341 cagtgacacg ggaatcaaaa ggtgaaaatg ccattatgat aattgaagta gatgatcctc
     5401 aagtagaaga aacggtaaaa agactcaaac agctgccaaa tatcgacagc gtaaattatt
     5461 tcgattaagg agctaaaaaa atgtttttat cgattgaaga attagtagat caagcaaaag
     5521 cttatccaag tgtagcagaa ttgatgattg cagttgaaat ggaaatgagt ggccgttccc
     5581 gtagtcacat catcgagatc atggaaaaaa acctctcagt aatggaacaa tcaatcaacg
     5641 agggaaaaga aggtgttacc tccgtcacag gaattaccgg tggtgatgca aaaaaattag
     5701 atgattattt aaatgaggca gactttttaa gtggagaaac aatcttaaaa gctgtacgca
     5761 atgctgtagc tgttaatgaa gtcaatgcaa aaatggggtt gatttgtgct acaccgactg
     5821 ccggaagcgc gggtgttgtt cctggtgtgc tgatggctgt ccgagatcgg cttgatttga
     5881 cacatgaaca gcaattggaa ttcttattta ccgctggcgc tttcgggtta gtcatcgcaa
     5941 acaacgcttc tatcagtggt gcagaagggg gatgtcaagc agaagttggt tctgcaagtg
     6001 caatggcagc agcagctttg gtttgtgcaa aaaatgggac tcctcatcaa gcagcacaag
     6061 cagtagccat tacattgaaa aatatgatgg gactgatttg cgatcccgtt gcaggcttag
     6121 ttgaagtccc gtgtgtcaaa cgtaatgctt taggctcttc tcaagctttt atctctgctg
     6181 atatggcatt agcgggtatc gaaagtgtca ttccgccgga tgaagtcgtt gctgcaatgt
     6241 accaagtcgg acgtcaaatg ccgtcgattt tcaaagaaac agcagaaggt ggcttagctg
     6301 ttacgccaac tgctaaacga cttgcggaag agattttaaa taagagggcg tgataaagct
     6361 ccttaatttc gagtattaag agattagtta tcttcataac aaaaaacgaa gagaggacta
     6421 attgcccttc tcttcgtttt ttattaatcc atcaatttcg tattttttac ttcatcgatc
     6481 gtttttgttc ctgcaagttg catcgtgatc gacaattctt tgttcaggtg ttcaaaaaca
     6541 gatgttactc cttctgcccc acctagattc aacccataaa tcactggtcg gccaatcgca
     6601 actaagtcag caccacttgc cagagctttg aagacatgct ctcctcgacg gacaccagag
     6661 tcgaaaatca ctggtacacg tttgttgact acttcggcaa tttttggcaa tacttcaaag
     6721 gacgcaggac ctccatctag ttgacgtcca ccatgattgg atacccagat accatctgcc
     6781 cctgcagaga tagcgattac tgcatcttct ggcgattgta ttccttttac gataactgga
     6841 agatgggtga tttctttgat tgttttgatg tcatctggtg tcaagccttg ttttgcagct
     6901 gcataaattt ctgcgattcc ttttccttcg ccattaccac ttgcactttg ttcgctatac
     6961 gcagctaagt taggcattgg taatggaaat tggaattgat tgatgacgtc ttcttcacgg
     7021 taaccaccga gcgttgaatc tgccgttaaa atgatagctt tagcccctgc ttctactgct
     7081 ttgttcaaaa tgaactcatt gaatctgtcg tctttactca tatataattg gaaaaactgc
     7141 ggtgcgcctg gcgctgcatc ggctgcgtct ttgattgtcg tatttgcata agtgctgatg
     7201 gaaaagattg atccagcagc agctactcct ttagctgtat cagcttcccc tttttcatgt
     7261 gccaatcctt gggccgctga tggcgcttgg ataatcggtg tatctaattc aattccgaaa
     7321 acagatgtat gcaaatcggc tgagtcgatt ccgcgtaata tccgtggcat gattttcttt
     7381 gtattaaaag aagtcgtatt ttctttcatc gtccactcat cttcagaacc accgcgaata
     7441 tagccaaaag ctcctgcttc catgcgctct tttacacgac cttctagtta ggcaatgttt
     7501 acaatatcga ttggatgttc ttcattactt gtatgataag tcatagtaga tccttctttc
     7561 atcttcttga ttacatataa atcatactaa acttacaaaa agtaagcaaa catttactct
     7621 cagatacttt tatcgctatt ctttccaaat aaatcgactt acaagctgat ctacttcttg
     7681 gttttcatga agcatactat gagaggcatt ttcacctgtc actacttttt cctctatttc
     7741 atttccgcgt tgcttcaaca acgcatagac cgctaatgca ctgtttaacg gtactgttcc
     7801 atcactcaag tctgtttcat ctagttgacc agcaatcaag aaaaatcgag tggttatagg
     7861 aatattaccg atcatttgct ggtaatcttg atagcggtta gaaacgacag caggcccctt
     7921 tgctaactca tctgtcagag actgcgcact atcatcgaca aaatcattaa aaggcgcgcc
     7981 aattgctgtt aatgtctgaa cttgtggcaa tgacgtatcc tgtccatacg ttcctaaata
     8041 gcgtagtgca ctaactcctc ccatggaatg ccccactatg ttgactttat ctatgccgta
     8101 gttttctttc agatacaaaa gacaagtttt gatccattct gcttgattcc actcgttatt
     8161 tttattatct tcaaacaata cttggaccat cggattgtct gcttttccag acaaatctcc
     8221 tgttgcttgt atttgtccat ctgttcctac tgttaaaacc aattctttta ctgcttgctg
     8281 atttttttcc aaacgccgca acatcccttt aaaggaattt tctgtcccgc tgtagccgtg
     8341 gaaaaaaagt gttggaatag tggttttttc tatcacttta ctggattctg ccgttttttc
     8401 tttatcagaa acttcagtag tatttatctt cgtcgtctgg caaccactta acgcaaacaa
     8461 actgataagg actaaagctg ctgcagttgc acgtttgcat aaatttttga ttggttctgt
     8521 catacacctc ttcctttcca tatagaaaaa agaaagactt gaaaggccaa tcatatgatc
     8581 gacatttcaa gtctctttat taatcgattt tatctacttg atcgaaatca agttctgtac
     8641 tggtttcacg tccaaacata tcgatgttga ctttcaattt ttctttttct ccgtcaactt
     8701 ctgttacttg tccttctaat ccagcaaatg cgccttcgat gattttcacg acttcgccaa
     8761 cttctacttc tagatcattt tgtcgcaggc tcataccgat agaacgcaag atatgattga
     8821 cttcttctgg aagtaatggt gctggtttgc ttccggctcc gtgtgaacca acgaatcctg
     8881 tcacaccagg tgtgttgcgg acaacatacc atgaagcgtc tgtcatgatc atttcaacaa
     8941 gtacgtatcc tgggaatgtt ttatgaacga tttctttttc tttcccattt ttgacttcag
     9001 tttctttttc ttcaggaaca acgacacgga aaataaagtc ggccattttc atactttgcg
     9061 cacgagattc gatatttgct tttactttgt tttcatatcc tgaatatgta tgcaagacat
     9121 accagttttt ttcaaaagat tccattgaag gctcctcatt tcattgtaaa ataaaaaaac
     9181 ctcagtacac ccgaagtttt tctttcgctt cattatagca ctaaaagtac gttgtggcta
     9241 gcgagttatt ttaaaatcca gccaaataag ctttggatgg ctgtatccat tacgtaaaac
     9301 atcaatccga aaataataga agtttcgatg actactaacg tatctttacg gagttgtttt
     9361 ctgcttggcc aagttacttg tttgatttca tcttttacgc tttttagaaa tttcatgaga
     9421 caacctccct tgctactgtt tatttcgttt ctttatgtaa tgtatattga ttacaatatt
     9481 tacaaaactt attgatttcc aaacgttcgc cgctttttcc ttcactgact gattttgtgt
     9541 agttgcgaga cccacaaacg gaacaagcga gtgctgcttt tttctttgcc atttacttct
     9601 gcccccttgc tgagaatcag acttatactt cataacagta tcacgtaact ttttacttgt
     9661 caatttgtga aataaactat ctattgtttt ggataaaatt atgatatgat taatttgaaa
     9721 ttaagctaaa atgagacaat tggaggtata gcgatgctat taaaaacact tgtatataag
     9781 aaaaaagatc tgacaaccgt tacagagact agtacattag aagaagcatt aaaaatttta
     9841 gaaacttccg gataccgttg tgtgccgatc ttagattctt caggtaatat tttccgtgga
     9901 aacatttaca aaatgcatat ctatcgtcat aaagcaaatg gcggtgatat gacgcttcct
     9961 gtcactcatc ttttgaaaaa cgctacaaag ttcatttacc tggatacttc tttcttcaaa
    10021 gtattcttta cgatcaaaga gcttccttat attgctgtcc ttgacagtga aaatcatttt
    10081 tatggtattt tgacacatag tacgttgctt aatatgctct ctcaatcttg gagcgtagaa
    10141 caaggaagct atgtactgac aattgcttcc acaggaaagc aaggagattt ggctgctatt
    10201 gcaaaaatca tttcaaaaca cagcagcatt gccagctgta ttactcttga tatcgaaaaa
    10261 gacgaataca ttcgacgtac attgatcacg ctaccggcta acactgaagc gaaagtatgt
    10321 gaaacgatcg tcaaccactt agagaaaaag aattataaag tggtagaaat tgaaaatttg
    10381 caaaaccaag aagcataatc aaaaagcgaa aaaagaaaac agctaatctg ctttcttttt
    10441 tcgcttttta taattagaca cgcttttcaa aatcaagcgc gcgatctaaa taatacatca
    10501 atggtgctga aacagccatg acgataaact cacttaatgc aagcgtgcca taggttgtcc
    10561 aaaatgcttg gccacctgtt ggaactaaca tataagcaat cagtcccatg ctgatggtaa
    10621 agaagatcgt gttcaatact aaacgcatct ttacattttt cactttgttt tgcaataaag
    10681 ctgtcaggcc taaagaaagc aatgtttggc cgccaccaaa aaccacatcc atgataccaa
    10741 aaccaaagaa ggcattatag acgatgaccc cgcctaaaac tccccaaagc aatttacggt
    10801 taaagacaac taaatgattc aaactttctg aaatacgaaa ctggatcggc cctgaggata
    10861 caggcgcaac taaaatagtt aacgctagat aaagagccat gatgatgcca tttacaacga
    10921 ttacggataa ccgttgtctg cttttcgttt tttgcatttt ctctcctctt ttctcctagt
    10981 ttttttaacg cgggatggtt gatgaaccgc ggttatgtga aacaaacaat aattataaca
    11041 gacttttcat ttatttcaat ccgtcttatc tgcttttaaa aaagcaaaag cttaaacaat
    11101 gtaaacgttt gctaaaaatc gtgggatatg gtataaagta agtgtaaggg gtcataagaa
    11161 ttcccagtaa agcagacgaa gtaggatctg caagaacaga attgttgtga aacttaaata
    11221 aataaaaaag gatgtgggaa tttgagcaac ctcttactag agaacggtct agcaagcagc
    11281 tgaagatcta agtggacatg ccgaaccttg gaacttctcc ttacgtaagt aatggatcat
    11341 gcgcttgcta ggcttttttg tgtttttcgg tcttcggacc tttttcattt tcctagactt
    11401 ctgctataat aaccaagaat taattttgta acagattttt ttgaaaaaac aagtttcttt
    11461 cattcaaaaa atagaaaaag cttgctaatt attggttaac cagcaaacag gagtattaaa
    11521 atatcttgtt ttattgaata gcaggaggaa atcatgaaat tccattatca tatattgatc
    11581 aatccatcgg caggcagcgg aaatggctat aaagtagcag aaagaatttt accggtatta
    11641 aaaaataagc atattgacta tacacttcat tatagtgaat acaaaggaca cgatgctgag
    11701 attgctgaaa ctttggcaaa agaaacattg attccttgga tagaagaaga acagaaaaca
    11761 atcgatactt tccccctttt gatcatcgta ggaggtgacg gcaccttaca tcaggtactt
    11821 gatactttct atcagatgga agtagaattc ccagttgctt atattccagc aggttctgga
    11881 aatgattttg ctcgaggggc aggccttcca aaaaatccca aaaaaggact tcagctgatt
    11941 ttagcagctc aatcaccaga aaaagtccac ataatggctt atgaagaaaa aataagtgaa
    12001 aaaaaaggaa tagctgttaa taatttcggt ataggattag atgcagctat cgtccatgcg
    12061 acaaatcatt cttccacaaa aaagcgattg aacaaataca acttaggatc attttcgtat
    12121 ttattctcta ttctccgtgc tttattcact caaaaaggat ttccaattct ggtagatgca
    12181 ggaggaaaac aattaagttt ttcaaacgca tttttatgta cagcaacgaa gcatcctttt
    12241 tttggcggag gaatcgcgat tgttccaact gctgatgcgt ctaaaccagt cattgatttt
    12301 gtcgtggtcg aacgaatcaa tttctttaaa atcttgtggc tcattctttt acttatacag
    12361 aaaaaacaat tgaaatcgaa atatttccat cactacacaa caaacagatt acgtatcgtt
    12421 tcaacaacac cgcaacatgg tcaagaagat ggagaagaaa tggaaaaacg accttttgat
    12481 atcacaataa ccacaactaa acagttgttt tggtgttaat aaaagaggtt ttgtcagaag
    12541 ctacatctgg aacaccgttt attcggaaaa aaggactgtg acacgacttt tgtcacagtc
    12601 ctttttttac tatgcagtta attctttgcc caattgggtt gccatcgata gtttctttct
    12661 ttacccaaaa taaattggat cattgaaaac accgcagcaa aagcaactaa gacacaacca
    12721 ttgaaccaaa aagattctgc aaatgtttga ttgtaactga gtgtttcact gatcaagtta
    12781 ttattttgaa caaaccaata tgttggtgtg aatgccgcta ttttgctaac catttctggc
    12841 aagtattctg ctggtacaaa caccccaccg ataaagcaac tgcctgtgat aaaaatatct
    12901 ttgatcccac cgctggtttc tgagtttttt accaatgaag tgatacaagc cgaaaagcta
    12961 atgatcggca ataaaaacaa gaaagtattt aaaatatgat accataccgt tatatcccac
    13021 gaggtgtgga tcactaacag aaccattaga agtaagaagc cactgaacaa cagcagcgag
    13081 taactaatca aactaaaggt tactttgcga ttcaagtttc gtttggtaat gggcgcactc
    13141 tggtttcgtt tactgatctc tttgcgatta aacgctagat tgatgacgct gaaaccgcta
    13201 aaaatggata gaaacaaccc ataagacaag aaattaaagg ttgtgcccgt caacagcttt
    13261 ttcatccgct gactatatcc cgcacttagc tcaacttctc cagtaaccga gagtgccatt
    13321 tgtgtctgtt ccatagctgc atcgattgtt ttatcttctt cttgaaacag aatcagtgtt
    13381 tgcaaaaagg tgttcacttg ctgtgtaaca actgttttag aaaaggcatc tgggcgactc
    13441 tgtatcttga tcgtcgccat ctttcctact tcgacttgtt cggtaaagtc tgcaggcaga
    13501 tgtaagataa tgtttacacg attaaaataa agagcatcat cgatttcttt ttgtgaggtt
    13561 ccatccaatg taacgactgt ttccttgtca ttcaaatatt tacgaaggcc atcgactaca
    13621 ggcgactctt cttcactaat caaggcgatt ttcgcatctt gcagagaggt attttcaaca
    13681 tcaatatttt gcgcaaaaaa gaatgtggca acaacagtga taattacacc tatcagtaaa
    13741 ttcgatttat ttgctttaag caatgtccaa atcgttttat aaagcgtcat aacgcacccc
    13801 tctttccatc caagcatttc ctaacgcaaa aaggaaaata aatccgatca accatagaag
    13861 attggtataa aaactagcca aatcagtgta gaaataaagt ttatacaaac tttcgctgat
    13921 caagttgacg agatttaatt gaccaacaat cggaatatga agatcaatcc aatacttcac
    13981 ttgttccgac cccatcatac cagcaaaaaa gctcatcgca atcgtcactg aaatcaagat
    14041 gctatccttt tgcaccagat tcatttttgg tatcaaatta ccaaccaatg tacctaacaa
    14101 aatcgcacac aacgacccca gagcggtaac aatcatcaac cattgccaac gttcaccaaa
    14161 gtctacttga tagataaaac gaaagacagc taacataata taaatctctg tcaaaacaat
    14221 cgtaaagctt gctgccaaat tagcgattga aactaacgat tgctttctag gaatcaagga
    14281 caagcgaata ccatttgacg attgatttgc ttgctgatcc tgtacattgc ggacccccca
    14341 catcgtcccg tagagaatcg ccattccaat cagagtgaag aaataaaaac ttttgaaact
    14401 catattacga cctgcatgaa cttcttgaaa agatacttct tgttcaaaaa cagtcatgat
    14461 gggcgcgaga tcaacgttct ccacttctgc cactttactc gaaattatac caatacgctg
    14521 taaaaattga tccatgacgt ttttcatcaa cgtctgactc attcctgctt gacccacatg
    14581 gagcgaaaca gatgaaccat caatgagata aaaaccagcc aaatcatctg catttagctt
    14641 ttcattcgct tctacttccg atagttcctg tacttcaaat aatggtttat cattgacttc
    14701 gacttgttct aagactgtgg taaaattttc cgaaagcgct gtttgatccg ctttgattac
    14761 aattccagta ttaatcgttt caagattgcc accttgatca atctcgccaa aggccgccat
    14821 aaacatcaat cctaaaagaa ttggaaaggc caatgtccaa aacaacatgg atttatttcg
    14881 cagcagtatt tttgtgcgat atttataaaa atgccaaaac attatttccc ctcctctagt
    14941 ctctcaaatc cttgccagta atctctaaaa agacatcatt caaggacgct tctttggttg
    15001 ctatttttcc gtaactgatc ttttcttctt gtaagattgt aagaatcggc aacaatactg
    15061 tatttagttc agtagttgtt acttggagct gacctttttt ataagcgatt ccatcagaag
    15121 ctattgttcg ctgaatcgct gacaacacat tttctgggag taatgggatg tcgatcgtca
    15181 aacgatccgc cgtccgtacc atatctttta gagattcttt ggttccttta gcaatcacct
    15241 gtccttgatc catgatcacg atctggtcgc aaagaatttc tacttcttcc atgtaatgtg
    15301 ttgtatagac aatggttgct ccttgtcgat tcagctcctt gatactttct aaaattttat
    15361 tccgactttg ggggtctaca gctactgtcg gctcatctaa aaaaattaac cgcggcttgt
    15421 gggcaatccc acatgcgatg ttcaaccgac gtttcaagcc accactaagt tctcctggac
    15481 gaaacgaaac atatttttct aatcccacta attgaatcac ctcttcaatc aaggctttcc
    15541 ttttctcttt ttcggaaaca tataaaccgc aaaaataatc gatattttct tgcacactta
    15601 gttcgtcaaa gaccgcaacg tcttgaggaa cgaccccaat cattgccttg acagcataat
    15661 tttcaggagt cattgttgtc ccgaacaatt taatggttcc tttgtcataa tttaacaaag
    15721 aaagcataca gttgatggca gtcgatttcc cactgccgtt tggacctaac agacctaaga
    15781 cttctccttc ttgtacttgc agatcaaaat gattcaatgc tacaaaatct ccatagcgtt
    15841 tgactaattt atcaatttcg ataatcatca tgaaaaactc cttccaaatt tcttgttgat
    15901 ctgactataa taaagtgcaa gaaaagaaac tagtgacgat tggctaaacc acacatgaca
    15961 tttgtcacaa tgaaggagtc tgctatgcat aaatctcggc tactcaacga aactagcttt
    16021 ctactggtta tctcattgct tttgctggta agtcaaggat tcgttgctat gcaagttatc
    16081 tatttattga tcgccgtttt attcactggt gtcagttatt tactgcctac aaagccaaat
    16141 tggattttcc aagttattct atttctttta tgtgcctttt tacctgatct tgtcctgttt
    16201 ctgccagcga cgatgcgagt gatcgcccct gaagaaagcc accttgatta cttgtttttg
    16261 ttaggttttt tgttgatttc gacggttggt aatcatcccc ccatcaaggt cgcctttgtc
    16321 gtaattttgc tgtttttttc cttttactta cgaaaaaaag atcaacgaac gaccgatctt
    16381 gagaaaaagt acattgtctc caaagatact cattgggaaa aacaacaaga gttatcggaa
    16441 caaaataaag cattggccct gtcacaagaa acacaattag ccttgcaaat tgtggaagaa
    16501 cggaaccgaa ttgcccgaga catccatgac aatgtcggtc atctgctgtc aagtgcgatt
    16561 ttacaaattg gtgcgcttga aatgatcaat caagaaccaa aactaaaaga accattagaa
    16621 aatttaagtg ccaccgttca cactgggatg gatcggattc gtcaaagtgt ccatgacctc
    16681 catgagacat cgatctcttt tcaacactcc ttagagtttc tgatcgctga ttttccttct
    16741 tctgttacga ttgaaggaaa cttgtttgaa ggattgaatg aaacgcagca aaactgcttc
    16801 ttaatggtca tcaaagaagc cttaaccaac agtatcaaac atagtcatgc caaaaccgtt
    16861 gttttacatt ttcgaacgtt gccggccttt tatcgcttgc aaatcacgaa tgatggcacc
    16921 agcccacaaa aaaattctgc tcccggtatt ggtttgaaaa cgatgcgtca acgtgttcaa
    16981 gaacaaaagg gacaagtcca tattttccaa gaaaaccagc aatttcagtt aacgatcatt
    17041 ttaccaaggg agggacacca atgataacag tagtcattat tgatgatgat ccatttgtga
    17101 cgaaatcgtt acaaaccatt ttagaaagca cgaaagagat ccgtgtgtta ggcattggtc
    17161 attgtgccaa ggatgcgcga aacccatcgt cccgatgttt tgctgacgga catccgcatg
    17221 cctaaacaaa cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc caaagccatc
    17281 cttttgcttt tgacgacatt caaagatgaa gaatacatcc gcgaagcatt ttccatcggt
    17341 gtcaaagggt atttaatcaa acagaacttg caagcgatta ttccttctgt caaatccgct
    17401 tataatggac aggccgtatt tggtaatgaa atcatcgaga ctttcactca aatgatgaag
    17461 aataaaccga cgattgatag tcatgcttat gcttctttta gtgaacgtga gcttgcaatc
    17521 atcaaagaag tagctgccgg gaaaaacaat aaagaaattg cagatgcctt gtacttgagt
    17581 gacggcactg ttcgcaatta catcagccaa ttactagaaa agctagattt acgggatcgc
    17641 acgcaattgg ctatctattt ttatcagcat ttgcaataag tcttatctaa cacaaaaaaa
    17701 cctgaatgat gctccttcgc atcattcagg tttttttcac atcttctatt caattgtccc
    17761 gcaaaccatt tcctcacgat tgaaagaatc aaggattcgc agggctgcca ggattcgttg
    17821 gattgttcgg cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt tctagttttg
    17881 attcttcacg atcgtctcgt tctacatcag gactttcatt caatttgaat tctttttcca
    17941 tctcatctaa ctttttaaag tcattgccag attcttttgc taatttcgct aatttatctt
    18001 cggtttcttt agccataaag taacgccccc cttttgattt cagcttagca tatcacactg
    18061 aaaaaacaaa agaaaacgct aaccaacgat catttttagc tatttctcat ctttaaaatc
    18121 aagcattttt tgccggtata aaatcgtagg gagaactgtt ttccatacca atcatcggat
    18181 ctactaactg gttatcgatc acttctgctg taagaacgaa atctttagaa acagcaggtt
    18241 ctacctcttc tttcttttct tctccaacaa atgaagaaaa cagatctggt tccactgttt
    18301 ccattacttg gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt agcttttctt
    18361 ttacaacccg tggctctttt gtatagttcc catcttcaaa tggatcattt ccgaccaaag
    18421 aatcttcata agctgctagt ttggtccgga gagtgatatt cattttatca ttatccatga
    18481 tccttgattt caacgtagtc atccggcttg ctgattcatt cgctacacaa gtgacatagg
    18541 cttgctcttc ccctaacaaa atcaacagtt ccttactgcg agtcactgcc gtgtagagca
    18601 aattacgctg aagcatccgc tgatattgat ggaccatggg caaaataacc atcttgaatt
    18661 cactgccttg tgatttatgg attgagcaac aataagaaag agtgatttta ttccattcgt
    18721 ttcttttata agtgacctca tttgcatcaa actggataac taattcatcc actttatctt
    18781 cagaatcttt tgccaagatg atacccgtga tttctcccat atctccattg aatacattca
    18841 attcgggagt attgactaat tggaggactt tgtctcctat ccgataaacg gtgtcgttcc
    18901 aatgtacttc cttttttcca ggtttccctg gattgaatat ctcctgcatc attttattta
    18961 acgcatcgat ccctgcaggt ccccgataca ttggtgctaa tacttggata tcttgtgcac
    19021 ggaatccctt atttttcgct ttttccacaa ttttagagat caagggttca atttgataag
    19081 catcacttcg gaaataggaa cgatcttttt gattctttgt gaaatctttt ggcagacgtc
    19141 cttctttgat ctcatgggca agaggaataa tactagaacc atcaccttgc cgataaatct
    19201 gattgagttc cattttggga atttgttcga tttccaaaag atcatggagt acttgaccag
    19261 gaccgacaga gggaagctga tctttgtctc ctactaagat aacttgcata ttcgtcggaa
    19321 tcgctttgaa taatgtgtta gccagccatg tatcgaccat agacatctca tcaacaatca
    19381 aaagtccgcc ttctaattct ttcgtactga ctgaaggtgt tttttcccgt ccattcagcc
    19441 ccagaagacg atggatcgta ctggcaggca gacctgtcgt ttcgttcatt cgtttagctg
    19501 ctcggccagt tggtgctgca agtagaatag gaaaaatttc ttgggtatat tttgaaggat
    19561 ccaattccag tccgttcaac tctgcaaaaa gattgacgat tccgttgatc acagtagttt
    19621 tccccgtacc tggtcctcct gttaaaataa atagagggga acggattgct tcagcgatag
    19681 cttgttcttg cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc cgaatattct
    19741 tctgcacttc tttttcagga taatggattt cttttttacg actgagaagg cgctggatcg
    19801 aattaccgat cccccattca gaaaagtaca aactgttttc gtaaagatta gtctcttctt
    19861 gttgtatctt tccttcttca acaagttgga taattacagt agcaacctga tcaggctgga
    19921 tttcaattgg gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat gtctccgccg
    19981 gtacgtatgt atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag atagctgctc
    20041 gaattcttct cggtgaatct gctgcaatac cgatttgttc ggctagatta tctgcacgtt
    20101 tgaacccgat tccttctatg tcttcgacta gctggtacgg attttcttcg atgatatcca
    20161 aagactcgtt cttataggcc tggtagatac tgaaagctaa ctgactaccg aacccgtaac
    20221 gattcagtcc catgatcact tgatccatcc cgtggtttag ccgaatcgtc tcagcaagca
    20281 tttctctttt tggcttcgtc aaaccggaga tttgttttaa taccgaagga tcagcaatga
    20341 ttttttcgat agcatcttct cccagcaatt ctacaatttt ttctgctgtt ttcttcccga
    20401 ttcctgggaa tttttcgctg gaaagatacg ctacgatccc atttgcagtt gttggctttt
    20461 cttgctcata tctttcgagt ttaagctgcc ttccgtattt aggatgatcc actaattctc
    20521 cataaaaacg ataagtctca ttttcttgaa tatcgccgaa acttccggtg actacaatct
    20581 ctttttcacg gtaatcagct gtggtttcac tgatgtgtac caaaagcact ttgtaaaaat
    20641 tactaggatt ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc atttcttctg
    20701 gctgcatcgg aagccgcctc cttcttctat agtaaaggtt ctggtgctgt ttcagttcct
    20761 aaaaaatctg tttggttcca tactttcagt tcatatggca ataatctgca aggctcttca
    20821 gtctctaaaa tcgtcaaact actattgaac aatccaccca tttcacgcaa ctcacttagc
    20881 tcttttcctg tcatccattg aatggctgca gttaaagaag ctccatgtcc tacgaataaa
    20941 agtgggccat ctttatgtcg ggcaaccgca tctgctacaa cagtttcgat acgtgtgatt
    21001 gccgattcaa tcgtttctcc gtgaaaagga gaaggatcat acagatctaa atgattacgc
    21061 aaattcggca gattatccgg atatttctgg tacatttcat cgatcgactg accttctaaa
    21121 gtacccagcc ctagttctct tagcttatct gtataaaaaa tctctaccgg acgagcaagc
    21181 tctttgttga taccttctgc tgtatcacgt gctcgctttg ctgtactgga ataaattgct
    21241 ttaaaaggaa catattttac ctttttccca aatgctttga tttcttcgta actttgtggc
    21301 aaaagcggag aatcgccatt gctcccttga aaacgtcttt cctgattcca ttgtgtcttc
    21361 ccatgtcggg taaaatatag ttccatacgc agcaaactcc tgtctttctt ttattttact
    21421 ctataataaa ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa ttctaaatta
    21481 gggaatcctt gctggcgaag tgcttcatac actatcattg cagctgtatt cgataaattc
    21541 aatgagcgga catgctcatc attcataggg atgcgtaaac acttttcttc gttttcacgc
    21601 ataaatgttt ctggcaaacc ggttgtttct tttccaaata aaaagaagtg ctcttctcca
    21661 tcagcaaaat tttcgtcact atatacttta tgggcaaatt ttgagatcaa atgtagttta
    21721 cgattaccta aaaatgttaa aaaagcttct aaattactgt ggtaagtaat atttacatca
    21781 ttccaataat ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa acctagtggc
    21841 tcgattaaat gaagcggagt attcgtggct gcacacgtac gggcaatatt tccagtgttt
    21901 gcagggatta atggttcaaa taaaacgata tgattcatca ggatcattcc tctcatattt
    21961 atgttcgttt ctattttctg acaatttgat ttttgcataa aaaaaaacgt atcaactcgg
    22021 tgtcagtcac tgcgagtcgt tacgttagtg aagctcttct cactaacttt tatcagaaca
    22081 ggaacctgat aaaaaccaat gaaaaaacaa cttgttgcta atataacacc ctcaactttt
    22141 ttttgcaacc tctactcatt aaaaactgct agaaaaacgt tttctcttag ttccttttaa
    22201 taattctatg tcaattgtaa tcttcttcaa aggattctta tataagtctg ctttgattcg
    22261 ctcttctacc tgccattcta aaggtgacat ggccaaaaga tctttttgat tttcctctgg
    22321 tatctcaaat tcataggtta cacgctgacg ttcagttaat ttcattgctt cagcaaactt
    22381 ggctactaca cgttcattgg aataactctg tttttcaggt tgattcggat aaaaagcctg
    22441 acgtagttcc tttaaataat tttcttgtgg caccaccttc aacacttctc catcttctga
    22501 gagtacacgt tggaattctt ggtaatgaga aggcgaaaag atatttaaaa ccgcgttgaa
    22561 tgtttgatca gcaaacggca aattggtcaa atcagctaca caccaaaatg cttcggcaga
    22621 ttgttctgta gctgcgtaga ctccttcttt tgaaatatca aatccaacag cattttgaat
    22681 ctttttcaat tttgaaagtt cattcaagaa gctaccttct ccgcagccaa catctaatag
    22741 cgagacttct tcaggtaaat gctgcgcaat agtctcaata acgggctgat acatgccaga
    22801 ttggatcatt ctacgccttg gaacgaacat tccttgatcg tattctgttt taaccgcatg
    22861 ggataaaaaa taaagtgttc cttttttgga aaggtcaaaa cggtgattat ttttgcatat
    22921 caagccatta tcagactttt ttacttcttc ttggcaaacc ggacagcgga acagctgatg
    22981 attttctgcc aaaaactggc gtcctcggtc aatttttttt aacatagttc cccctcattt
    23041 ctgttttatc ttaccgttag atgctcactt tggcaactgc taaaaatatg atacaatgcc
    23101 tagaagaaag tgaaagataa aggagaagat tagatgatca aagaattttg cgctgaaaac
    23161 tacacatcta ttcctctagc aattgctaga ggagccgatc ggatcgaatt gtgtgacaac
    23221 ttagcggtcg gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt aagttatgct
    23281 ggggaaaaag atatccccgt aatgacgatt attcgtccta gagggggcga cttcgtctat
    23341 aacgatatcg aattgaaaat catgcatact gatttgattg aagcaaagaa attagggacg
    23401 gatggcgtag tatttggttg tcttactcct tcaggctggc tagacgaaga ggccttagaa
    23461 ctattgatcg aaacagcaga agggttgcag atcaccttcc atatggcttt tgacagtatt
    23521 cctgaagatc ggcaattcga agcaatcgat tggctggtag aacatggtgt tgaccgtatc
    23581 ttgactcatg gcggtcctgc tgacaaaact attgtagaaa atttcccacg gcttaaagaa
    23641 ttgattgcct atacagatgg ccgcttaatc attttgcctg gtggtggtgt cactgcagag
    23701 aatgcagcac atgtagctaa agaattgaac gtaagcgaag tacacggaac caaaatcgtg
    23761 gatcttcagt tataatctta taaacaaaaa aacatttgca acaggcataa tgcttattgc
    23821 aaatgttttt gtttttttac ataaaatagc ccataaataa agaagcaata ttgaaataaa
    23881 tcagtacact cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct actgctggat
    23941 caaatcctag acgatccatt agcatcggga ttaaactacc tgcaagattc gccactgtga
    24001 ttgcaaatag catagccatc cctatgacaa accccaagat aaaattatgt ttccaaaaac
    24061 ctacgattag aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg gtcaagactt
    24121 cagccaaaac aagtcgaaca aatccatgat ctttctcatc agaaatcgca agtcgacgaa
    24181 cagccacagc tagcgactgg gttccagcat taccggcagt tcctgtaatc agcgaaatga
    24241 agactgctaa aatactcgct tcacttacca agtcttcata gtgactgatt aaagaagcgg
    24301 tcgacatacc taaaaacaac agagtgatca gccaaggcaa acgtcgagac gctgccttta
    24361 ctggattttc attaatttct tccacattga ccccggcaag tcctgaataa tcgctagcag
    24421 cttcatcatc aataacgtcg atgatatcat cgactgtgac gattcctaac aaatgatcat
    24481 cataatcggt aacaggaaga gctaagaagt cataatctct aaatgtttgt gccacatctt
    24541 cttggtcgtc gcctacatga actgaaagca ctcgttcgct catcagatca gaaatcattg
    24601 cgtcgtcatc attcacgatt aggtcgcgca gagaaataac ccctactagc tgaccttctt
    24661 gattaacgac atagatgtaa tagattgttt cagctacatc tgcttcgttc ttcagcacgt
    24721 acatcgcaga gcgaacagtt tgattggcta cgatcgaaac aaattcagtt gtcatgatcg
    24781 cgccagccgt ttcatcctcg taatggagaa gttccttgat ttcactggca tcgtctgccg
    24841 acatcaaact taaatattta gcaatttgct ttttatccag cgtattaagc aagtcaacag
    24901 cattatctgt atacatctca gaaagcatat cagctgcata gctaggacgc atttcatcta
    24961 ggtattcttt catatgttcg ttgtcttctt caatcacatc gaacatatcc gctaattctt
    25021 taggcgacag ataggaatag atcagctgcc tgttctcttc tgtaagagat tggtagaatt
    25081 gcccctgctc atagatatgc atctctaaaa aactgtttct gaatgcctga atattatttt
    25141 cccttaaatc ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt tcatccaaac
    25201 caatctcacc tcgccttatt cttcaaaccg tctcacaact gcctccatgt ctgcggctaa
    25261 aggctgcttg aactccagca actcttctgt aaatggatgg taaaaacgca gatcataaca
    25321 atgaagggct tgtcttttta ttcccagatc cattcgcccg ccatacatat catcaccgag
    25381 cagggcacag ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc ctgtatgcag
    25441 ctggatatca actaacgcga tttctgttag tcgcttctct atccagtact cagtctgtgc
    25501 cgaacgtcct tcatcagaga ccattcgctt caatagcgaa gaataatctc gggcgatcgg
    25561 caaatcgata tgtccatgtg ccgataaatc tgaaagcctt ccactgacta aggcctgata
    25621 ttttttcaca aacttctttt cacgaagttg catatctaat tttgcgtgcg caaatccatg
    25681 ctttgcaaaa agcatcaagc cagatgtatc ccgatctagt cgcgtcacca catggattac
    25741 ttggttttcg taaccttgtt ttttataata agcctttaca cgattagcca ttgtcccatt
    25801 tggatggtat tgggcaggaa tagacgaaac gcctgctggt ttatttacta ccagaacgtg
    25861 ttcatcttca tacacgatat cgatcggtgt ttcatccaaa agtacggttt catgttctcc
    25921 ttcagcagga atcacaatgg ttaccttatc atccttagct agagaaaaca agacattttc
    25981 tacttgatca ttaactttga tttgaccgcc ttgaaatttt attttcgcta acagaccctt
    26041 tgagatccct ttttctttta aaaaatattt tacttgctga gaatgatctt tctcataatc
    26101 ccatgtaaac tgcatatcaa tcctcactaa taaaggcatc tttcacacga tgccaaaaat
    26161 gcatatgtcg ataagaagca aaatggatcc gttcttctgc tattcgataa taaattgagc
    26221 ggatatttgc ttttgcgaca ttcaattgat caaccgttac aagataatct tctgtatttt
    26281 ccaattttat ttctagccat tcatcatggg caatcacgat cggagaaccc aaagtacgaa
    26341 acactcgatt attcagtgaa gcaatctctg ccaactgaaa ggcattgata ctaggatgga
    26401 tcacagcacc gccgacactt ttattatatg ctgtcgaacc agtaggcgta gaaatcgtca
    26461 atccatctcc tctaaaactt tcaaacagct cgtttttgat gtatacatcg gctaccatcg
    26521 tacgattggc ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg tccggtgttt
    26581 catccaaata actgatccga acatccagca agggataact aacactttgt tcccggttcg
    26641 ttcgtaagct gtctactagt tcttccagct cgtaatcccg ccaatccgtg taaaacccta
    26701 aatgacctgt atgcacgccc aagaaacgca catcattcag acaatgactg tagtgatgga
    26761 acgccgacaa taatgtgccg tctccgccga ctgagatgac caattctggc tcatgatcat
    26821 ctcgttgaat ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact tctatagtct
    26881 ttgcttcttt attatgaacg atcgctactt tcatcccctg cctcctctct ttcgctttct
    26941 ttcttcaaaa gcgttcgata gtagacatca tctgattttc ctcttccatg ggagaataac
    27001 cgctgtgctt cttggatttc ttcacggata ctggacatct cttcatccaa ctgataggca
    27061 gcttctgccg cacgctgaag tcgttcactc atttcttctg gaaaaacgcc ttgatattta
    27121 taattcagcg aatgctcaat cgttgcccag aaattcatcg caagagtccg aatctggatt
    27181 tccgccaaaa ttttcttctc accgctgatc agctgtacag gatactcgat caccagatga
    27241 taagaacggt agccacttgc ttttttattt gtgatgtaat ctcgttcttg gagaactttc
    27301 atgtcttttc ttttacggat gatctcaaca acttgatgga tatcttctac aaactgacac
    27361 atgatcctta acccggcaat atcagacatt tcttcttcta aacgtcccat tggaatatgc
    27421 cgtaattgtg attttgttac aatactatcg actggcttga ctctcccagt gacaaattca
    27481 atcgggacat gtcgattttg ttcacggaac tgtttgcgga tcccccgcag tttcactttc
    27541 aattctgata cagtttgttc atatggtgct aaaaatgctt cccaatctcg ttccatagct
    27601 gatacctcta cttcattaac attcattgtt tattctacca tatatgcaaa gttttttcgt
    27661 actcttgatt tatgcattga ccaaaaaaag aaaattaggc aaaatagaca aaaaggagtc
    27721 gatcaaatga cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa gcaagagtac
    27781 gagatattca tcgctcacta tcaattaaca gataaagatt tccgtgtaca gactaatatt
    27841 tatttcgata ccgttgatga acagctgaag aaacaaaatt gtggcctacg gatccgtttc
    27901 gttggtcatc aagctgaata tacattaaaa acacctgctg aaaaagggcg tctcgaaaca
    27961 acggatacct ttataacaga agaagcagaa gcatttatct tcgaaaaacg tctgcctcgt
    28021 tcaggcgcag tttttcaaaa actttctgat ttgaatatcg atcctgcttc attaatccaa
    28081 accggaaagc ttacaacaaa acgagctgaa ttccctattg aagaaggact tttagctatt
    28141 gatgaaagct ggggagacaa tctacacgat tttgaactgg aactagaggt aggggatgca
    28201 tctgtgggaa aaattgcttt tataaatttt ttaaaacgtt tttctttacc ttatcgtcct
    28261 gctaagaaca agatccaacg tatgcttgaa gctaaaaatt agaaaccttt cattttcaca
    28321 aggcacttga gttcattttt ttactttttt ctgttaagtt ataggatgtg aaagaatcta
    28381 gtcactagtt gtatagaatc tattttgggg gagattcata tgatcgaaat ctatttattt
    28441 gttaatcctt taggggaata ctgtttcgaa atggaacaac agttattaca atttatcgaa
    28501 gaagagtacg ggacaccatc aaaagaaaag atgcaatttc gctttcttcc tttggtcaat
    28561 ttgcagacaa ttggggatgt catgcaacaa aaaggaattt ctcagaacaa tcttgaggaa
    28621 cgtaatcact tattctcaat gacttattct gcagcattgg actgcaaagc ggcgcagttt
    28681 caaggaaaga aaaaaggccg ccgttttttg atcaaattgc aagaagcagt cggctgtaat
    28741 gacataccat attctcaaga acttgctgaa tccatatttg aagaaatcgg cggcgatttg
    28801 aatatgttta aagaagatcg tcagtctgac ttcgttaaag aagtattctt ttctgatcaa
    28861 aaaattgctc gggaaatggg catcacaaaa cacccttctg cagtcgttta caattatgcc
    28921 tgcgaccgtg attttggtgt tttagtagaa gtaaaaggta caagtagcct ttggagaatc
    28981 acagagctgt gtaaaacaac agataactca tatcaagttt ttaatggtga acatttacat
    29041 acaaatgatt ctcagttcca ttcaagaact agccatttac acttgctttc taattaa
//
LOCUS       DAFLWC010000029        29096 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.029, whole genome shotgun sequence.
ACCESSION   DAFLWC010000029 DAFLWC010000000
VERSION     DAFLWC010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29096
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.029"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            278..1063
                     /locus_tag="L1V17_001180"
     CDS             278..1063
                     /locus_tag="L1V17_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1235960.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            1076..1927
                     /locus_tag="L1V17_001181"
     CDS             1076..1927
                     /locus_tag="L1V17_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HBN1235961.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(2051..2503)
                     /locus_tag="L1V17_001182"
     CDS             complement(2051..2503)
                     /locus_tag="L1V17_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1235962.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(2968..3336)
                     /locus_tag="L1V17_001183"
     CDS             complement(2968..3336)
                     /locus_tag="L1V17_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HBN1235963.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            3486..3968
                     /locus_tag="L1V17_001184"
     CDS             3486..3968
                     /locus_tag="L1V17_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HBN1235964.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            4005..5015
                     /locus_tag="L1V17_001185"
     CDS             4005..5015
                     /locus_tag="L1V17_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBN1235965.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(5130..5843)
                     /locus_tag="L1V17_001186"
     CDS             complement(5130..5843)
                     /locus_tag="L1V17_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235966.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(6033..6623)
                     /locus_tag="L1V17_001187"
     CDS             complement(6033..6623)
                     /locus_tag="L1V17_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBN1235967.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            7107..7334
                     /locus_tag="L1V17_001188"
     CDS             7107..7334
                     /locus_tag="L1V17_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBN1235968.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            7350..8516
                     /locus_tag="L1V17_001189"
     CDS             7350..8516
                     /locus_tag="L1V17_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBN1235969.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNAHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            8750..9793
                     /gene="hrcA"
                     /locus_tag="L1V17_001190"
     CDS             8750..9793
                     /gene="hrcA"
                     /locus_tag="L1V17_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HBN1235970.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            9887..10450
                     /gene="grpE"
                     /locus_tag="L1V17_001191"
     CDS             9887..10450
                     /gene="grpE"
                     /locus_tag="L1V17_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBN1235971.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            10501..12330
                     /gene="dnaK"
                     /locus_tag="L1V17_001192"
     CDS             10501..12330
                     /gene="dnaK"
                     /locus_tag="L1V17_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBN1235972.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            12481..13647
                     /gene="dnaJ"
                     /locus_tag="L1V17_001193"
     CDS             12481..13647
                     /gene="dnaJ"
                     /locus_tag="L1V17_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBN1235973.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(13729..14394)
                     /locus_tag="L1V17_001194"
     CDS             complement(13729..14394)
                     /locus_tag="L1V17_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1235974.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            14370..14543
                     /locus_tag="L1V17_001195"
     CDS             14370..14543
                     /locus_tag="L1V17_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235975.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            complement(14588..15325)
                     /locus_tag="L1V17_001196"
     CDS             complement(14588..15325)
                     /locus_tag="L1V17_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBN1235976.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(15327..16829)
                     /locus_tag="L1V17_001197"
     CDS             complement(15327..16829)
                     /locus_tag="L1V17_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HBN1235977.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            17088..19082
                     /gene="uvrB"
                     /locus_tag="L1V17_001198"
     CDS             17088..19082
                     /gene="uvrB"
                     /locus_tag="L1V17_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBN1235978.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            19092..21908
                     /gene="uvrA"
                     /locus_tag="L1V17_001199"
     CDS             19092..21908
                     /gene="uvrA"
                     /locus_tag="L1V17_001199"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBN1235979.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            22171..23436
                     /locus_tag="L1V17_001200"
     CDS             22171..23436
                     /locus_tag="L1V17_001200"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HBN1235980.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            23440..24171
                     /locus_tag="L1V17_001201"
     CDS             23440..24171
                     /locus_tag="L1V17_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HBN1235981.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            24306..25190
                     /gene="rapZ"
                     /locus_tag="L1V17_001202"
     CDS             24306..25190
                     /gene="rapZ"
                     /locus_tag="L1V17_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBN1235982.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            25187..26185
                     /locus_tag="L1V17_001203"
     CDS             25187..26185
                     /locus_tag="L1V17_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBN1235983.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            26219..27154
                     /gene="whiA"
                     /locus_tag="L1V17_001204"
     CDS             26219..27154
                     /gene="whiA"
                     /locus_tag="L1V17_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBN1235984.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            27697..28347
                     /locus_tag="L1V17_001205"
     CDS             27697..28347
                     /locus_tag="L1V17_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1235985.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            28534..>29096
                     /locus_tag="L1V17_001206"
     CDS             28534..>29096
                     /locus_tag="L1V17_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HBN1235986.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
BASE COUNT         9565 a         4897 c         6176 g         8458 t
ORIGIN      
        1 aaggggctgt gacaaaagtc ttgtcacagc ctttttttcc aaataaatgg tttttcagaa
       61 gtagcttctt cggaaataag ccgaaatttc ttgaagctga ccacttctgt cacaacctct
      121 ttctttatag aaataaaagg acactagcaa ttcatgaaaa cgattgctag agcgtatcat
      181 ttgctttaga ctatatatct tggtgtacac tcactttaag gcggaaataa aagttatccg
      241 taataacagg tttaggtatg aaaaaggagt gggtactatg tacaaggaat tagaaaacaa
      301 agtcgcagta gtaactggtg gctcaaaggg gattggaaca gcgattgctc aacgattcgg
      361 gaaagaaaaa atgaatgtag ttgtcaacta taactcggat aaagaaggag cagaaaaagc
      421 agtcaaagca atcgaagagg caggcggaaa agcagtctct gtacaagcag atgtcagttc
      481 tgaagaagga atacagcgtt tacttgatac ggctttagaa aattttggga cactggacgt
      541 ttgggttaat aatgctggga tggaaaatca gcatccaacc catgaactta gccttgaaga
      601 ttgggaaaga gtgttaaaag tcaatttgac tggcgttttt atcggaacga aagcggcttt
      661 aaattacttt acagagaata ataaaaaagg aaatatcatc aatatgtctt ctgttcatga
      721 acagatccca tggccaacgt ttgctcatta cgctgcttca aaaggcgggg taaaattatt
      781 taccgaaacg gtagcaatgg agtatgcacc gaagggaatc agaatcaata gtataggccc
      841 tggtgctatc cgtacaccta ttaatgcggc aaaatttgat gatcctgaac aaaaagaact
      901 cttggaaagt atgatcccac taggacgcgt aggtgaacca aaagaaatag cggcgacagc
      961 tgcatggttg gcttcagacg aatccagtta tgttacaggt attacactat ttgcagatgg
     1021 tgggatgact ttatatcctt ctttccaagg tggaaaagga taagggtgaa taaaaatggg
     1081 tttattgatt gcattgatcc cggcagttgg ctgggggatc cagccactga ttttgaaaaa
     1141 gattggtggc agaccaacaa atgagatatt aggaactggt attggagcgg tgcttgtcgg
     1201 cttactcgtt caattattcg cttctccagc tggtatttca gtgactacat ttttgattag
     1261 tttactttct ggtgcatttt gggttattgg acaaacagga cagtatacat ctttcaactt
     1321 gattggtgtt tctaaaacga tgccaatttc gactgcatta cagttagtcg gaacctcgtt
     1381 gattggtgtc ttcgcttttg gagaatggtc tggaagtatg gggaaaatca ttggagcagc
     1441 agcaatcatt cttcttgtat ttggttctgc tttaacggca atcagtgatg atcctggaaa
     1501 aaaaggcggt atcacaaaag gaattagtct attagcatca acaagtattg gttattgggt
     1561 atacagtgca ttgcctaaac tagttgatgc aagcggactt tccattttct ttccgcaaat
     1621 gatcggtgtc tttttagggg cagtgattta tgtgattttc cgtaaaccaa ccgcattttc
     1681 tgaagacaag agttggaaag caacgatcgt tggagccatc tttagtgtgt cagcattggc
     1741 ttatattttt tcagcaaatg aaaatggggt tgctactgca tatatcatta cacagctaaa
     1801 cgtagttatc tctacattag gcggtatgta catcctgcat gaaaataaga caccaaaaga
     1861 aaaaaaatta acgattatcg gattattgct gatcgtagta ggaagcatgg tcacggtctt
     1921 tatttgagga taaagatggt aaaatttcat ttattaaaaa aatatttgtt tgaaccaaac
     1981 agtaagtact tataaaaaaa tagcgctaga atttccaaca tctctggaat ttctagcgct
     2041 ttttaattgt ttaagataca agggaaatat ctgtctggat caataatttt tcattgatcc
     2101 attgactaaa gtttacgaca taattgaagt taccaccgat tagtatctcc gcatgattgt
     2161 ctttataaag atcgtattgt aaaagacggt cttttttatt tgcgtaaaca tcgttatggt
     2221 actggactaa ttgttctcgg aattgattga ttgctgtaaa atcacgatat tgaaggttga
     2281 aacgcatcgt gattggtgca tttagcatga atcgctgcat ttcttttgct gcttcctctg
     2341 cttgatctcc gtataggaac tcaaaaagat tacgttcaga aaatttccat tgcccgccaa
     2401 cctttgttcc ttttagtttt ccttcatgaa gataatttct gatagaacgt gtagtaacac
     2461 ctaattgttc ggctaattca tttactgagt aaaaatcttt caatgttcac cctcctatgt
     2521 gaatggttct actgacttag ttgatatttg cttaatcacg aaatgtagaa agaacgattt
     2581 taattaaggt cattgtaaaa atcaagtcag aaaattctaa cttttatttc tctaaagaaa
     2641 ttcgttctct cctaaagtga tattatattt aaatatacct gaaaataatg ggcagtatta
     2701 tgaaagatca ctgatatttt ctcgtatttt ttccttattc aaaagttttg caggaaaatt
     2761 gctgaaaaaa taattttact aagtagaaaa ttcaaagcca ttcaatcagt gatttttttc
     2821 agcacaagaa agactcctta taaaaatagc agatactttg tcaattaagt gtttaaccag
     2881 ggatgataaa aaggatagga ttgaacaaaa cctgtataag gtgatgaata gtttcctcgc
     2941 cagtaaaagg tttattcgta taaagcttta tcgccaaaat ttatcatgac cttttttatc
     3001 ttcaatatta aatgaaatca attgttcaat caattcccag ttgattacac ttttccaagg
     3061 aactttgatg acgttatccg tatatacgta gcctgcttct tggatatttt tttcaagggc
     3121 acgaatcgct gctttttccg gtgcgataga aaaatgattt ttagcaaaac taaatgcaat
     3181 aataaaggta ccatggtcag taaacatagg ttggttccat tttacagttg tgtctagctg
     3241 gggatacgtt tctgttatct tagcaaaaag gtctttgatc ttttgttgat gttctttttc
     3301 tttgatttga ttgatgatcg gctgaaattt ttccattcta aaacgcctcc attaagtggt
     3361 ttgatttatt ttaccagaaa aacaatagtt atgtataaaa aacgaacaaa acacaagtaa
     3421 tgttgtaacc gctatattta tatgataaga tgtctcaaat aataaaatag aaaagagaca
     3481 taaaaatgat tgacttggca aagaaattct tacacgaaaa tatatatttt gagttgtatc
     3541 atcatcgagc catttataca aatgaagatg ctttggtaat aaagaaagaa caaggattta
     3601 caggtacaga gaccaaaagc ttattcttaa aagataaaaa agataataac tacgtatatc
     3661 tgacttttac tacgaaacaa acggatttca aagcattagg gaagatcgtc ggtaaaaggc
     3721 tttctattgt ttcatcagaa cgcatggaag aacaaacggg acaaaagcag ggcgctgttt
     3781 ctccgtttgg ttatgaaaaa cagattccga ttattattga tgaagagctc ttatcaaatg
     3841 aaaaacttgt ttttgcacca ggtagaccag atcaaacgat ggtcatccaa acggttgact
     3901 taaacaaaat catccagcta cttgagatgc cgatattttt gatgccggca aacgaaaaaa
     3961 acaattaacc aagtaaaata gtgcatactt ggaggtgaag caacatgata agttatccat
     4021 tattagaaag aaatgcaacg attggggtta ctgcaccatc ctcaggcgta tcagaggaac
     4081 accattcgtt actcgaatca gctttaaaga gaatggaaga aaaatctttc caagtagtta
     4141 ctggaaagac gctttggacg caagataagg aaaaatcagg tccagcaaga aaacgagcag
     4201 atgaattcaa tcaaatgatg caagatgaaa atatccaaat gatctttccg acttggggag
     4261 gagaattatt gattgagatt ctcgattttg tcgattttga tgctctacaa ccaaaatgga
     4321 tagtaggtta ttcagatatt agtacgttgc tacttgctgt cacattaaaa acagggatag
     4381 ccactgcaca tggaactaac cttattgatt taagaggaga gtacttggat gaaacgacag
     4441 caatgtggga aagtgtactg aaaacaagag aaggagaatc gattctacag caatcttctg
     4501 aaaagtatca aaaagtgtgg ccccatgagc attcatcatc ttctgttttc catctcactg
     4561 aaccaacaaa ttggcaatca gtcagcggag atgcagtaag gatgaaggga cgattattag
     4621 gtggttgtat tgatacgatc aggcatttaa tcggtactcc ttatggagat gtccaatctt
     4681 ttaaaagaaa gtataatgat ggaaagccga tcttgtggtt tctagaaaac tgtgagctat
     4741 cgtcagttga tttaagaaga tcacttgttc agatgaaact ggcaggctgg tttgatggca
     4801 gctcggggat catgttcggt agaagtgcgg cagaggattt gttagattat aaaatgaagg
     4861 atgtatacga agatctgtca aaggaattaa aactaccgat cttgtatgat attgattgtg
     4921 gtcatgtacc gccacaactg acattgatta atggtgccta tgcagaagta gcggtagaag
     4981 atagaaaagc gactgttttg caaacgttta tttaaaaaat tttttcctgc cttggagtct
     5041 atcaaagacc aataaatcta aatagaaaag aaagtgaaag aagctgacaa aatgctgtca
     5101 gcttcttttt gtataacata ttagaaagtc taattatcta taactgtcac atcgattaac
     5161 tgtttcacgt cattgggatt tcctgtagga atagctacta cagatgcatt atcaatgatt
     5221 tcttgagttg tttctctaat gaacgctgga taagatgttt gatctgcagg catttgccaa
     5281 tgtgaaggaa ctggataact agtgattgtc ccgtcatggt tacttgaata cactaaaact
     5341 ccctggtaac tgtatttccc agtgagcata accacatctt tcggatagac tgcactccct
     5401 gcatcataag gggcgatagg tgttcctgca ggataatgaa taacatgtaa ttcgaaatca
     5461 cccgatgtat ctctaaaagt attacctcta atagctagcc aaacacgtgc gtactcaatt
     5521 tgtagatcag aatatcctgc taacggatct attgactgag aagactgtga ggaggttgtg
     5581 tctattgttg aagaagaaat atttgtctca actgtactac tagatgtaga agaagtattg
     5641 ggctctgaga ctttactgct tgttgaagat gtattcgttt cagtagaagc tgatttctga
     5701 gtacttgatt tttcagctga actggtttgt ctgattgaac ttttgtctgt ggtcgcagat
     5761 ggatcactat tttctttact aggagacgta catcctacaa ggaataaaga gaccaacaat
     5821 aaaataaaac ctaacttttt catataaaat acctcattat ttttttaata ccagtatagc
     5881 ataatcctga atttttgaat ccgtaaaacc ttgtctatga atataaatag agtgtatctt
     5941 ctttgataaa tgtcagaaaa agtgtgacaa ataatcatca gtaaaattac ttgtcacact
     6001 attgataagg agtatttaat tgaagagaat gattaggaga aaggatctcc gtacttttta
     6061 tagtaatcat agaatccaag tttgtataga cgaatcgttt tttctcttat ttcttctgtt
     6121 tcaaaatgga ctgcttgaag aatcaagtct gtgaattcta taggagctgt tccattcgca
     6181 gtaatcaaat tacgatcttt cacagcttgt tgttctataa aatcttcttt attctgataa
     6241 ttttccgatt ctaaccaagg aaattgcgca tttccggtgt gtttgtaacc ttgcaataat
     6301 ccgctctgag ctaaataatc aactgcccca caaatagcag ctactggtac gtctgttttt
     6361 aacaatttat cgattatttg atataaatga tgatttttta tgtcccatga attgccaccg
     6421 atcataataa aaaggtcaac tttttcaggt atttgttcga ttaagtaatc gatttttgtt
     6481 tttaatcctc caatggaagt gacctctgat tggatagaag cagttttgtt ttgccatttc
     6541 tcattttggt ttagtgtgct agtaatataa gcaccttccc aatcggcata ttcctctaat
     6601 agaaacgtaa tcgcagtttt cattttcaag ctctccttta ctatctataa caaggacaac
     6661 agttttaacc tacagacatt cattaaaatt gggtagcgac agcgaaaaca acaattctta
     6721 agttttagac agagtataca gatagtcaac ttaattaaat acgaactaaa taaaaatgac
     6781 aggtaatcat ttttgtttac cagcattata acattttgca tacatggatg acaaaagaac
     6841 caattcccac ttgcttgagt acaatattaa aagaaactgg aaggcaaaaa gtaattatag
     6901 aaacgaaaaa taaatcatat cgggcactca gacatgaaaa caaccctaga gatatataac
     6961 taggtaacca gtttaatgaa agaaaaaatc atccaagaag tcgattcttg gattttttag
     7021 tggatttgtt cgccaaatac gtttagtatg cgtatatgag aggttgtaag caaagcgttg
     7081 tggtctgagc acttaaggag gaatctgtga aaatagcttt tcatattttt gcagattttg
     7141 acttaatgcc gaaggtcagc tttgcgatta ccgtttatcg agaggctgta aaagcaccgt
     7201 gtagctccga tgacaataag caagcatttt tagagctagg tttccttgat tctaaatatg
     7261 cggcttattt caatgagttg gtgcttgaac gcgattttaa gaaggtcgaa aacaggcacg
     7321 acttttcgac gtaaggagaa agaatttcaa tgatagaaac aataaatccc gcagaaaaca
     7381 aggtttctgc gtacattcat atcccatttt gcgagcatat ctgctattac tgtgatttta
     7441 ataaagtttt tttagaaggg cagccagtag atgagtatgt ggaaatgctg ctgaatgaaa
     7501 tgaaaataat gctagaaagt catccgacag cgaatttaga aacactttac gtagggggcg
     7561 ggacaccaac ttctttatct gctaaacaac ttgatcgact gttatcaggt gctagagaga
     7621 tcctgccttt tcaaaatggt aatgagttta ctgtagaagc gaatccaggt gatttgaccc
     7681 gtgaaaaact tcaagtaatg aaaaactatg gcgtcaatcg tttatccatg ggagtgcaga
     7741 catttgataa tcgcttattg aaaaaaattg gacgtaaaca caccgcagaa gatgtgtatc
     7801 aaactatgca atttttagaa gcagaaaatt ttaccaatgt aagcatcgat ttgatttatg
     7861 cattaccggg acaaacacta gaaggatatc tggatacttt ggaaaaagct ttggctttgg
     7921 atctgcctca ctattctttg tactcattga tcctcgaaaa caaaacaatg ttcatgaact
     7981 gggtacgaca aggaagactc gaactgcctg atcaggaaac ggaaaccaga atgtttgaag
     8041 agacgattga agcaatggaa aagcatggac gtcaccaata tgaaataagt aactttgggc
     8101 tctccggaca tgaatctcaa cataacctca tgtactggaa caatgcccac tattttgggt
     8161 ttggagctgg tgctagcggt tatcttggag atattcgtta ccgcaacaaa ggaccaatcc
     8221 aacactattt acgcccatta cgagcaaatg aacgcccggt attggaagaa gaaaaattga
     8281 cacgaaaaaa tcaaatagaa gaagaaatgt tcttaggact aagaaaaaaa acagggatta
     8341 ctaaaaaaca tttctatgat cgctatcaaa aaacaattga atcggtgtac ggtgatgtgc
     8401 taagggaatt agagcaagaa gggttacttg ttaatgaaga agaccgtgtt tatttgacac
     8461 caagagggac ctttttgggg aacaatgtgt ttgagcgctt tttgtttgaa aaatagttta
     8521 aagaatattt gttttttatc tgaatttaaa taaaaaaagt tcaaaaatac aataaaggac
     8581 tattgaaacg ttgatataac tggatttaca tcaattattt agaattagca ctcttgtgtt
     8641 tagagtgcta aaaaatggag tctttctctt gacaggagaa gggcttcttg ctatatttat
     8701 aagtggatta gcacttagaa tatatgagtg ctaatgagag gtgaggaaga tgttaacaaa
     8761 gcgacaaaac gacattttac gtctgatcat ccaacactat acgagtagtg gcgtgcccgt
     8821 tggttccaaa acattgatgt ctgagggagt caaggccagc tcagcaacga ttcgcaatga
     8881 tatgaaagca ttagaagatg aaggattgct gttgaagact cactcttctt ctgggcggat
     8941 tccatctgct ttaggctatc gttattacgt ggatcatttg ttaaaacctg ctcgcgtagc
     9001 agaagatgat ttgctgctga ttcgtcagtc tctaggcaga gaatttcatg aaatcaatga
     9061 gattattaag caatctgctg agatattatc tgagctgaca agctatacga ctttttcatt
     9121 gggacctgaa ataaaagacc gccgactgac tggctttcgt atcgtaccct tgaataatcg
     9181 acagattatt gctatcgtcg taacagatat ggggaatgta gaaagccaag tgttcactct
     9241 tcccgaatat atgggaagtc aggaactaga aaaaatggta cagattgtaa acgaccgtct
     9301 agtcggagat cctctgatga cggtgtacca taaacttcgt acggagattc cgatgattct
     9361 tcataaatat ttccaaacga cagaagggat gtctcagtta tttgacaccg ttcttggtca
     9421 tgtttttgaa gataaggttt atgtcagtgg acaaatgaat ctcttggatt atgagccccg
     9481 tcaagatctt gatcagttca aatcgatgtt ttcttttatg aaagactcag acggacttac
     9541 acaaatgatc actccgatgg atagcaatat tcatatcaag attggtgctg aattaggcaa
     9601 tgatttattg cagaatatga gtatgattca agcaagttac gagatagatg gtcatggaag
     9661 aggtacaata gccttgttag ggcctactag tatgccttat tctcggatgt tcggtctagt
     9721 cgatgtttat cgaagagaac tagcagctaa acttgctgat tactaccgtt cgcttgactt
     9781 gtcaaactcg taatgtgaat aacgaagcta tttgcagctg atcgttctct ctttcttagt
     9841 aagagcaatc aaacagctga ctgaataatg aaaggaagac tgtatcgtga aagaaaatca
     9901 agaagaacta gataaagaaa tgacagatgc tcagccagaa ccggaaatcg atgtcgaagc
     9961 tgcagaagat tcgggtattt cagaagctga agcggaagaa ttcgaaacag cgaaattaaa
    10021 agctgagtta gaagaaatgg aagataaata cttgcgggct cgtgctgaaa tcgcaaatat
    10081 ggcaaatcga ggaaaaaatg agcgtgagca attacaaaaa taccgttcac aagatttagc
    10141 caaaaaatta cttccatcaa ttgacaacct ggaacgtgca ttagccacag aagtgtcaga
    10201 tgatcaaggg gcaggtttga aaaaaggcgt ggaaatggtc ttggaaagtt tgcgtaacgc
    10261 actggaagaa gaaggaattg aaaaaatccc tgctaaagga gaagcctttg atcctaatct
    10321 tcatcaagca gtacaaactg ttccagcgac tgaagataca ccagccgata cgattgtaga
    10381 agtactacaa gaaggctaca aattacatga tcgcgtgtta agaccaacca tggtcattgt
    10441 tgcacaataa ttgtgcggat ataaaactta cactttcaat taaagaagga gacgttaatt
    10501 atgagtaaaa ttatcggtat tgacttaggt acgactaact ctgcagtagc agtattggaa
    10561 ggaaacgaag caaaaatcat cgctaaccca gaaggaaacc gtacaacacc ttctgttgta
    10621 tcattcaaaa atggagaaat ccaagtaggg gaagttgcaa aacgtcaagc tgtgacaaac
    10681 ccaaatacga tttcatcaat caaacgccat atcggtgaag caggttacaa agtagatgta
    10741 gaaggtaaat catatacacc acaagaaatc tcagcaatga tccttcaata tatcaaagga
    10801 ttcgcagaag actatttagg tgaaaaagtc gaaaaagcag ttatcactgt gccagcttac
    10861 tttaatgatg cacaacgtca agcaacaaaa gatgctggta agatcgctgg tctagaagta
    10921 gaacgtatcg tcaatgaacc aactgcagct gctcttgcct atggtttaga taaaacagat
    10981 cgcgacgaaa aaatcttagt attcgacctt ggtggcggta cttttgacgt atctatcctt
    11041 gaactaggag acggtgtctt tgatgtattg tcaacagctg gcgacaacca tctaggtggg
    11101 gacgactttg ataacaaaat catcgactac atggtagcag aattcaaaaa agaaaacagc
    11161 attgacttgt ctcaagacaa aatggcttta caacgcttga aagacgctgc tgaaaaagcg
    11221 aaaaaagatt tatctggcgt atcaagcaca caaatcagct tgccatttat cacagcagga
    11281 gaatctggac cattgcattt ggaaatgaca ttgacacgtg caaaatttga tgaattaaca
    11341 gctgacttag tagaacgtac aaaagtacca gtacgtcaag cgctaaaaga tgcaggttta
    11401 tcacaatcag aaatcgacga agttatttta gtcggtggat ctactcgtat ccctgcagtt
    11461 gtagaagcag tacgtaaaga aacaggaaaa gaaccaaaca aatcagttaa ccctgatgaa
    11521 gtagttgcta tgggtgctgc tatccaaggt ggcgtgatca ctggtgatgt gaaagatgtt
    11581 gttttacttg acgttacacc attgtcatta ggtatcgaaa caatgggtgg agtgttcact
    11641 aaattgattg accgcaatac aacgattcca acaagtaaat cacaagtatt ctcaactgcg
    11701 gcagataatc aaccagcagt agacatccat gtattacaag gtgaacgccc aatggctgct
    11761 gacaacaaaa ctctaggaag attccaattg acagatattc cagcagctcc tcgtggtatt
    11821 ccacaaatcg aagtaacatt cgatattgat aaaaacggga ttgtaaatgt atctgcgaaa
    11881 gatctaggta cacaaaaaga acaaaaaatc acgatcaaat cttcttcagg tctaacagac
    11941 gaagaaatcg aacgtatggt aaaagatgca gaagcaaatg cagaagcaga taaagctcgt
    12001 aaagaggaag ttgacctacg taatgatgta gatgcattgc tattctctgt ggacaaaaca
    12061 ttgaaagaat tagaaggcaa agtggacgaa gaagaagtga aaaaagcaga aacagctcgc
    12121 gatgaattga aagccgctgt tgaagcaaac aacatcgaag aaatgaaaac taaacgcgat
    12181 gcattgaacg aaatcgttca aaacttgact gttaaactat acgaacaagc ggcacaacaa
    12241 caagctcaag aaaacccaga agcagctcaa ggcggagcag atgatgtcgt tgatgctgat
    12301 tttgaagaag tcgatggcga cgataaataa tcagttcact gaatttcgag agaaggccaa
    12361 agttgctact ttggcttttt cttttgaaaa atagtttgaa gtatcggttt ttgtttcaaa
    12421 caaaatatga tatgataaca agcgacgtga aaatgatgag aaccaatagg aggaaagcct
    12481 atggcaacaa aacgtgatta ttatgaagtc ttagggctct caaaaggagc atcagaagat
    12541 gaaataaaga aagcttatcg taagctttcg aaaaaatacc atcctgacat caataaagaa
    12601 cctgatgcgg aagaaaaatt caaagaagta tcagaagcat atgagatttt aagtgacccg
    12661 caaaaacgcg ctgcatatga ccaatacggg catgcaggca cagatccaaa ttacggtgct
    12721 ggtggagctg gtggcggatt tggtggattc ggcggcttct ctggtggcgg cttcggtggt
    12781 tttgaagata tcttcgactc tttctttgga ggaggcggtc ggtcagtcga tccaaatgcg
    12841 cctcgtcaag gtgctgattt gcaatatacg gtcgacttgt cttttgaaga agcgattttt
    12901 ggtgtagaaa aagaaatcaa gtataatcgg gaagaaatct gtcatacttg tggtgggaac
    12961 ggtgcaaaac caggcacaca accaactact tgtcataaat gtcatggtgc aggtacgatt
    13021 aatgtagaac gccaaacacc acttggacga gtgatgagcc gtcaaacttg tgatgtttgt
    13081 catgggacag ggaaagaaat caaagaacct tgtccaacct gtcatggctc aggacatgag
    13141 aagaaagcac attcagttaa agtgaatgta ccagctggtg tagaagaagg acaacaaatg
    13201 cgtttagctg gtcaaggaga agctggagaa aacggcggac catttggtga tttgtatgtg
    13261 gtcttccgtg tagaagaaag tgatatcttt gatcgtgaag gttctgaaat ttactatgaa
    13321 ttgcctttaa gttttgtaca agcagctttg ggggatgaag tccaagtacc aactgtccat
    13381 ggagatgtga aattgaagat ccctgctgga acacagacag gtacgaactt ccgtttacgt
    13441 ggaaaaggcg ctccgaagtt acgtggtggt gcaacaggcg accaacatgt caaagtaaaa
    13501 ctgatcacac cgaaaaatct aaatgaacaa caaagagaag cattacgtgc attcgctgaa
    13561 gctggcggca tcaaagttga agaacagcaa gaagacggtt tcttcgataa gtttaaagat
    13621 gcttttggcg ggaaaaagcg gaagtagttt ttctagtaaa aacgctaagt cattaataat
    13681 taaaaaccag acgaacaatc atatgttcgc ctggtttttt tgtagttgtc atgtttgtac
    13741 caacaaaaaa gccagcttta gaatatgata atcgtcatag tttctagggg tataaccagt
    13801 gagagaatgg aacttgttca atcgatattg caaggtgttt ttatgaataa ataattcttc
    13861 tgagcaattt ttgatgcttc cgttattttt actgaagcat gccaaagtct tcttgaacaa
    13921 atgtacttct tcttctgtca ggcttttcaa aatacgtttt acatataatg ttcgttgatc
    13981 tgacgggatt gctggtaaaa cgatcccgag gtctaaatct tcaaaaaagc ggatctcgtt
    14041 cacagattga tggaaagcta tccattcgca aacttgtttg gcatgaagga aagattgcgg
    14101 tgtctcttgc tctgtataac aaagcgaccc aattccaaag tttagctgta actgatacat
    14161 tttattaaac tttgtctgga ttttatcaag caatgatagc aatgaggctc tggaaatccg
    14221 attgactagg ataatgattt gttgtctatg tacagtgagc aaagcctgtc cgtaataaga
    14281 gaagaccctt tcgagcaact ccaataaagg attgatccgt tcttgacaca attgctgatt
    14341 gtcagaaagt tgtcccacaa ctacataata tggagaagaa aaatcaagct caattaagtg
    14401 agggtggtat cgactatgta cttgatatca tcaatgaacc gatggtactt tcttatgcga
    14461 tggaacaggt agagcgattg cttgtttgtg caggaaaaca agcgatgcgg ctgatacgat
    14521 taggtgagaa aataagaaga taaaaataca cggtcccttc atggcgaccg tgcatttttg
    14581 gtttttatta aatatttaat actttattca agaaatcttt tgtccgttca ttttgcggat
    14641 tttcaaagat ttgttgaggc gttccatctt ctaaaaagtt tccgtcgtca atgaacatga
    14701 cgcgattggc cacttcttta gcgaacccca tttcgtgcgt aacgataacc atcgtcatac
    14761 cttgttctgc taactttttc atgacgttca agacatcacc gaccatttca ggatcgagtg
    14821 cagaagtagg ctcatcaaaa agcatgatgt cagggttcat cgctagagca cgagcaatag
    14881 ccacacgctg tttttgtcca ccagaaagca tttcaggata catatctttt ttatcttcta
    14941 gaccaactgt ctgcagtaat ttgattgctt ttttctctgc ttcttctcta gattctttct
    15001 tcaggtccat cggtgctaaa atgatgtttt ccaaaataga aagatgaggg aataggttaa
    15061 agtgttggaa taccattccg atatgttgtc tcaccaagtt gatatctgtg cttttatcca
    15121 tcaagtgggc gccgtcaata ataatttcac cgtcagaagg ttcttctaaa cgattcaagc
    15181 aacgcaagaa tgtacttttt cctgaacctg aagggccaat gatacagacg acatctcctt
    15241 cgttgatgga tacattgatg tcgtttaata ctgtgttatc gccgtatttt ttgactaaat
    15301 gctcaactaa gattttttct gccatcttac ttcaccttct tttctaaaac ttttgctaat
    15361 tttgtcaatg ctgtgatcaa aatcaagtac atgatcgcaa tgatcaagta aacatacgta
    15421 ctttgtgttg tacgtgcaac aatgatctta ccagtttgca gcaattcgac tacaccgatt
    15481 gcggaaatga tcgttgtgtc ttttaatgag ataacgaact gattgacgaa tgatgggatc
    15541 atgatgcgta tcgcttgcgg caaaatgatt ttttgcattg tccgattata agaaagacct
    15601 aaacttctgg aagcttccat ttgtccgaca ggaacggcgt tgatcccgcc tcgaacaatc
    15661 tctgcgatat aagcacttgc gttaagagtc aaggtgataa caccagcaag gaagtcagga
    15721 atcgtaaatc caacgatacc aggcaaccca aagaaaataa agaacgcaag aaccatcatt
    15781 ggaattcctc ggatgatatc gacataaata ctagcaattg tgcgaagagc gcgtattggt
    15841 gctacactga ataatccaaa aatcacaccg attactatag ccaaagcaaa ggagatcaaa
    15901 gttaggagaa ttgttctcca aagtcctttc aacaatgctt gatagttgtt ttggataagt
    15961 ccaagaaatg ttgattcatc agcagtggaa gactcactgg aagtttctga accatccgct
    16021 acatattctt taataatctt atcgtattcg cctgttcttt ttaattcttt caatccttca
    16081 ttgaacatat taagaagctc aggattttgt ccttttttaa cggcaaatgc atattttccg
    16141 ccagattctt ttttgatcgg tgtttccaat tcttgtcctt gtttgatcgc ataaccgatt
    16201 accggataat catccatcat tgcatcgatt gcgccaactt ttaacccgtc gtacaattga
    16261 tcagcagcat caaaatattt gatagaatag ccatattcag attcatggtc gcttaaaaat
    16321 tcagcacttt cggtaccaac ttttgctccg actgtttttc ctttcaaatc ttcataagac
    16381 ttgatcgaag tatctccttt tttgacagct aattggatcc cgctatcaaa gtaagaatca
    16441 gaaaaatcat agcttttctt tcgttcatct gttacagtca ttccggcaat cattccgtct
    16501 gcttgtcctg attccaaagc ttgcaaagca gcagagaaac cacggtagtc cattcggatg
    16561 ttaaatcctt gcagtttggc gatgttttcc atcaatttta catcgatgcc ttcgtactcg
    16621 ccctttgcgt tttgaaattc aaatggagca aaagcagagt cactggcaat tacgtatacg
    16681 tcttttttgg gctctatttt ttgcattgtc tcgcttgtgc ttgactctgc cgttgtagtg
    16741 ttgtcagctt gtgcaacatg accaaacgca agtgtcacaa gtcctgtcat taagaaaaca
    16801 aatgagtgaa ataaatgctt tcttttcata atcaacctcc taaatttcca atattttatt
    16861 attataggcg aaaagtgctg aatcagacaa gactgtaagc tcgaaaaaat gaaaaaaatg
    16921 cgagtttcta acattttatg ttataaaaca taacatgtat aataagataa aaaagtggcg
    16981 aaagtatgtt cggtgtggta taatttttta gtaaggaatg cctttgcttt ccttttcttt
    17041 ttattggtcg taaaatgaaa aggaatgaat gaaaaggagg acgaagaatg attgagagag
    17101 atacctcccg acactttgag cttgtctcga aataccaacc ggctggtgat cagcctgaag
    17161 cgattaacca attagtggat ggcgtagtcg gcgggaaaaa agcacaaatc ttattaggtg
    17221 cgactggaac agggaaaaca tatacgattt ccaatcttat tgagaaagtg aataaaccaa
    17281 cactgattat tgcccataac aaaacattgg ctggtcagct gtacggggaa ttcaaggaat
    17341 ttttccctaa caatgctgtt gaatattttg tttcttatta tgattattat cagcctgaag
    17401 cttatgtgcc ttcaagcgat acgtatatcg aaaaagattc aagtgtaaat gatgagatcg
    17461 acaaattacg acattcggct actagttcat tattagaaag aaatgatgtg atcgtcattg
    17521 catccgtttc atgtattttt ggattaggct cgccttttga gtaccaaaaa caagtagttt
    17581 cgattcgaca gggagcagaa ctagatcgca atcagttgat tcgtgactta gtcagtatcc
    17641 aattcgaaag aaatgatata gattttcagc gcggtcgttt tcgagtgcgc ggtgatgtcg
    17701 tggagatttt tccggcttca agagatgaac gtgccttacg tgtggagttt tttggagatg
    17761 aggtcgaacg tatccgagaa gtcaatgcac tgacaggtga agttttagga gaaacggaac
    17821 acgtagcaat cttcccggcg actcactttg tgacgaatga tgaacatatg gagcatgccg
    17881 tagcgaatat caaagcggaa ttagaacagc gtttaactgt cttgcgaaat gaaaacaaac
    17941 ttctggaagc tcaacgttta gaacagcgaa ccaattacga tattgaaatg atgttagaaa
    18001 tgggctacac gtcgggaatt gaaaattatt ctcggcatat ggacggacgt aaagaaggtg
    18061 aaccgcctta tacgctattg gatttctttc ctgaagattt tttgatcgtg gcggacgaat
    18121 cgcacgtaac catgcctcaa atcagaggaa tgtataatgg tgaccgagcg agaaaacaga
    18181 tgctagtaga ttacggtttc cgtttgccat ctgctttaga caatcggcca cttcggttag
    18241 aagagtttga aaaacatgtc aatcagatca tttatgtctc tgcgacgcca ggaccatatg
    18301 aacatgaaca aacagatacc gttatccaac aaatcatccg tccgacaggg ctgcttgacc
    18361 cagtgatcga agttcgtcca atcatgggac aaatcgatga tctagtaggc gaaataaatg
    18421 aacgagtcga aaaagaccag cgggtgtttg taacgacatt gacgaaaaaa atggcagaag
    18481 acctcacaga ttatttcaaa gaattaggga tcaaagtcaa atatttgcat agtgatatca
    18541 aaacgctgga acgaacagaa atcattcgag atcttcgatt aggtgaattt gatgtgttag
    18601 ttggaatcaa tttgcttcgt gaaggattag acgtacctga agtttccctt gttgctatct
    18661 tggatgcgga taaagaaggc tttttacgta gtgaacgttc cttagtccaa acgattggac
    18721 gagctgctcg gaatgaagaa ggtaaagtaa tcatgtacgc agacaaagta acagattcta
    18781 tgcgtctagc gatggatgaa acgtcaagac gtcgtacgat tcagcagaag tacaatgaag
    18841 aacatgggat cgttccaaaa acgatcatta aagaaatccg agatttgatt tctattacga
    18901 aagaatcgga agatgataca aaagaagcgg tacaagtctc gtacgaagaa atgacgaagg
    18961 aagaaaaaga cacgttattg atgaaattag aaaaagaaat gaaagatgcg gcaaaagctt
    19021 tggattttga aacagccgcg aatgtgcgag atatgatttt agaattaaaa gcttcaaagt
    19081 aggaggacaa catggctaac gataaaatta cgattcatgg tgcacgtgcc cataacttga
    19141 aaaatataga tgtaacgatt ccacgagata aattcgtggt cgttacaggt ttgtccggtt
    19201 ctggaaaaag ttccctagca tttgatacgc tgtacgctga agggcagcgg agatacgtag
    19261 agagcctttc tgcttatgct cgtcagtttt taggacaaat ggataagccg gacgtagata
    19321 gcatcgacgg attgagtccg gcgatttcta ttgatcagaa aacaacaagt aaaaatcctc
    19381 ggtcgacagt aggtactgtg acggaaatca atgactattt acgcttgttg tttgcacgtg
    19441 taggacatcc gatttgtccc aacgatcata tcgagattac cagtcaatca gtagatcaaa
    19501 tggcagatca agtaatggct ttgcctgagc gcacaaagat ccaagtgttg gcaccgatcg
    19561 tggtaaagaa aaaaggacaa cataaaaaaa tattcgaacg aatccaaaaa gagggatacg
    19621 tccgcgttcg agtcgatggt gagatctatg atttaagtga agtgcctgag ctggagaaaa
    19681 acaaaaaaca tgatatcgcg atcgtcatcg accggatcat tgtgaaagaa gggattcgtt
    19741 ctcgcctatt tgattcttta gaggcggccc tgcgattagc agacggctat gctctggttg
    19801 acgtgatcgg tgaagaagaa atgttgttta gcgaacacta tgcctgtcct tattgcggat
    19861 ttactgttgg cgaactagaa ccaagactgt tctcattcaa tgcgcctttt ggagcttgtc
    19921 cagactgtga tggtttaggt gtcaaattag aagtcgatca agatttagtg attccagata
    19981 gaacgaagac acttagtcaa ggtgctatcg ttccatggaa tccaatcagc tctcagtatt
    20041 atcctcaaat gttagcgcag gcttgtgaaa gtttcggtat cgatttagat acaccattcg
    20101 aagaattacc ggaagagcat caggagatca tcttgaatgg gacagatgat cttttccatt
    20161 tccattatga aaatgatttt ggtggcgttc gcgatgtaga aacgactttc gaaggggtat
    20221 tgaagaatat cgagcgtcgt tatcatgata cgaacagtga tttcacgcgt gagcaaatgc
    20281 gtctttatat gacagaatta acttgtcaga catgtaaagg ttatcgattg aatccccaag
    20341 ctctatctgt tcaaatcaat ggaacgaata tcgggcaaac aaatgagttg tctattcaaa
    20401 aagcagtaga tttcttctca aacttaacgt tatctgaaca agagaaagta attgccaaac
    20461 cgattttaaa agaagtaaat gacagacttt cattcttgga aaatgtggga ctagactatc
    20521 taactttgag tcgcgcttcc ggaacattat ctgggggaga agcgcagcga atcagattgg
    20581 ctacacaaat tggatcgaat ctttctggag ttttgtatat tttagatgaa ccatcgatcg
    20641 gattgcatca acgcgacaac gatcgactga ttggctcatt aaagaaaatg cgtgatcttg
    20701 gcaacaccct cgttgtagtc gaacatgatg aagatacgat gtgggcagca gattatttga
    20761 ttgacgtcgg acctggggcc ggagaacaag gcggacaaat cgtggctgca ggcactcctg
    20821 aagaagtagc taatgatgaa aattctttga cagggaaata tctttcaggg aaaaaatcaa
    20881 tccctgtacc aaaagaacgc cgtaaaggta atgggaaagc aatcaagatc actggtgctt
    20941 cagaaaacaa tctgaaaaat attagtgttg aatttccatt aggagaattt gtagcagtca
    21001 caggtgtgtc tggttctgga aagagtacat tggtcaatag tatcttaaag aaatcgttag
    21061 cgcaaaaatt aaataagaat tctgctaagc caggtaaatt caagacaatt tccggctacg
    21121 aaagtatcga aaagatcatc gatatcgatc aaagcccaat cggccggacg ccgagaagta
    21181 atccagcgac ttatacaagt gtatttgatg atatccgtgg gttatttgct caaacgaacg
    21241 aggcaaaaat gcggggttat aagaaagggc gttttagttt caacgtaaaa ggcggtcgtt
    21301 gtgaagcttg tcgcggggat ggaattatta agatcgaaat gcactttttg cctgatgtct
    21361 atgttccttg tgaagtatgt catggtaaac gatataattc tgaaacatta gaagtgcatt
    21421 acaaaggaaa aagcattgct gatattttgg aaatgacagt agaggatgct gtagaattct
    21481 tcaagcacat tccaaagatt catcgcaaac tgcaaacgat tgttgatgtt ggcttaggtt
    21541 atgtgacgat ggggcaacca gcaacgacat tgtccggtgg tgaggcacaa cggatgaaac
    21601 ttgccagtga attgcacaaa atctctaatg gaaagaattt ctatatacta gatgaaccaa
    21661 cgacaggact tcatagcgat gacatcgccc gcttgttgca tgtattacaa agattagtag
    21721 atgctggtaa cacagtttta gtgattgaac acaatctaga tgtaatcaaa acagcagatt
    21781 atatcattga tttaggacca gaaggtggag aaggtggagg aacgatcctt gcgactggaa
    21841 caccagaaga aatcattaac gtaaaagaaa gttatacagg tcactatttg aaaaaaataa
    21901 tggtataaag aggatagata gctgagatag ttaaaaaaac ataaaaaaat gaatttttgc
    21961 ttgttttatt aatatcagtg ttctagaatc attacatggt agttctttct acactgattg
    22021 gtatagataa aaacttccta taagttcaat ccgttcaaaa aagaattgag caatcggagg
    22081 actttccttt gattgctttt ttctttatgg tatgatattc cttgtgtagt tggaaaagaa
    22141 aaacaagaga ttatgagtaa gtgagagata atgatgaaca gtattgaaaa tgaagaattt
    22201 atccctatat tattaggaag cgacatgaac gtttatggta tggcacgttc ttttaatgaa
    22261 gcatacggca aaatctgcca agcatatgct tcggatcagt tagcccctac ccgctacagt
    22321 aaaattgtca atgtagaagt tattccagga tttgataaag accctgtatt tatcgagacg
    22381 atgcttcgtt tggcaaaaga aagatattct gataagagta aaaaatatct tttgattgct
    22441 tgtggtgatg gatatgcaga attgatctcc caacataaac aagagctgtc agaatatttt
    22501 atctgtccat atattgatta ttctttattt gaaaggctga tcaataaagt aagcttttat
    22561 gaagtttgtg aagaatatga tcttccgtat cctaaaacat tgatcgtcag agaagaaatg
    22621 ttagtaaatg gacatttgga acaggaattg ccttttgaat tcccagttgc tttgaaacct
    22681 gcaaacagtg tggagtatct ttctgtccaa tttgaaggaa gaaaaaaagc ttttatttta
    22741 gagactagag aagagttcga tttaatttta ggccggatat acgaagccgg ttataaaagt
    22801 gaaatgattg tacaagattt tatcccgggt gatgatagta atatgcgtgt gctaaatgcg
    22861 tatgtagatg aagatcatca agttcggatg atgtgccttg gtcatccact attagaagat
    22921 cctacaccag catcgattgg taattacgtt gtgatcatgc cagattataa cgaaaaaatc
    22981 tatcaaacca ttaaggcatt tttggaaaaa atcgaatata caggctttgc caatttcgat
    23041 atgaagtatg atcctagaga tggagaatat aaattatttg aaatcaattt gagacaaggt
    23101 cgtagcagtt tctttgtgac attgaacggc ttgaatctgg ctcgttttgt cacagaagat
    23161 cgagtgttca acaaaccctt tgttgaaacg acctatggaa cgaatcaatc agataaagca
    23221 agattatgga tgggtgtgcc caaaaaaatc tttttagaat atgctcggga aaatgaagac
    23281 aaaaaactag ctgagcaaat gatcaaagaa aatcgttacg gtactactgt attttatgaa
    23341 aaagaccgat caatcaagcg ctggttgttg atgaaatata tgttccataa ctatattcca
    23401 agattcaaaa agtattttca tgtgaaagaa ggctagttca tggagaattt tttcagtatt
    23461 ttaggcggaa tgggcacgat ggcgacagaa agttttgttc gcttgatcaa ccaccgaacg
    23521 aaagctacaa aagatcaaga atatttgaat tatgtcttat tcaatcatgc aacagttcct
    23581 gatcgtacag cttatatttt agatcgatca gaagaaaatc caatgccgtt tctgctggat
    23641 gatattgaga aacaaaattt attgcgacca aacttcattg tgttgacttg taacaccgca
    23701 cactactttt ttgaagagtt acaagcggca acggatattc ctatcttgca tatgccaaga
    23761 gaagcagcaa atgaacttgt ccgtcagcat acgacaggga gagtagcgat tctaggaaca
    23821 gaaggaagta tgaaagctgg aatctatgaa cgcgaagtca aaaatcttgg tttcgaaaca
    23881 gtgattcctg atactgcgct tcaagaaaaa atcaattacc tgatctatca tgagatcaag
    23941 gaatcggatt atttgaatca agagctctat tacgaaatct tagaggaagc ggtagagcgc
    24001 ctaaactgtg aaaaagtcat cctaggttgc acagaattat ctttgatgca tgaatttgct
    24061 gaagataatc attacccagt gatcgatgct caatctattt tagcggatcg aacgatcgaa
    24121 cgtgcattag ctgaaagaag cgaggcattg gatacagcat cggaaaagta aaaaaattgg
    24181 atttggggca aatatcctaa aagatatttg gtccaaatct ttttgtaaaa gaaaaagaaa
    24241 actggtaatg atacgcccgg gatgatataa ttttattatg cacaatgtga gaggggttcg
    24301 taaatatgac agataatttg caattagtca tcataacagg tatgagtggt gcagggaaaa
    24361 cagtagctat ccaaagtttt gaagatatgg gctatttttg tatcgataat atgccgcctc
    24421 gattgattcc aaaattctgg gaattgatca aagaatcagg taaagtcaca aaaatggctt
    24481 taggagtgga tttgcgttct cgttccttct ttgaagaaat ccaaaacatg ctgatcgaaa
    24541 tcgaaaatac gaacttcatc gacacttcta tcttattttt agatgcttca gacgaagaac
    24601 tagtggctcg ctacaaagaa acaagacgag cacatccaat ggcgatggac ggtttgatca
    24661 ctgaagggat acgtaaagaa cgggcgatac tagacgactt gaaagcccaa gcttccgtga
    24721 tcattgatac gacaacattg acaccacgac aattacgtga aaaaatcaat gagtcattca
    24781 aatcaaaggg agaccaagga tttcggatcg aatttgtatc atttggtttt aaatacgggt
    24841 tgccgatcga ttcggatatt gtgatggatg tgcgtttttt gcccaaccct cattatatcc
    24901 cggaactaag accattgacc ggaaaagatc agccagtcta tgattatgtg atgtcctttg
    24961 atgaaacgca atcattctac cataaatttt tggatcttct ggaaactgta ttgcctggat
    25021 acattaaaga aggaaaaagc agcttgacag ttgcaatcgg ctgtacaggc ggtcaacacc
    25081 gttctgtggc attgactgaa cgtttggcaa atgctttagg gaaaaactat aaagtcaatg
    25141 tgacacatcg ggacaaggat aaaaggaaag agacggtgaa ccggtcgtga aaatgaaaac
    25201 ctaccggata agaaaaccaa agatcgtagt ggtcggcggt ggcactggtc tgccagttat
    25261 cctgaaaagt ttacgaaatc aaggagcaga tatcacagca gtagtgactg ttgcagatga
    25321 tggtggaagc agcggtgcaa tcagagaatc gatcgctatg gctcctcctg gtgacttgag
    25381 aaatgtctta gtggcgttat cggatatgcc acaattctat gaagatattt tccaataccg
    25441 tttcaaaaag gaagatcagt ttttagccaa tcatacgatc ggtaatctga tcattgccgc
    25501 agtttccgag atgcggggaa gcacttatga ggcgattcaa ttattagcaa aaatgatgca
    25561 tgtagatgga catgtttatc cttcttcaga aactcctttg accttgcatg ctgtttttaa
    25621 agacggaacg actgcagtag gagaatctaa aatcgcgatc aaccgtaaaa ccattgaccg
    25681 tgtgtatgtc tgcaacacaa atgataaaag tgaagccaaa gcggctcgaa aagtcgtttc
    25741 agcaattatg gacgccgaca tggtcgtttt gggacccgga agtttattca ccagtatcct
    25801 tccaaattta gtgataccag aaatcggcga agcaatgctc aagacaactg ctgaaaccgt
    25861 ctatatctgt aatatcatga cccaaaaagg ggaaacggaa catttcacag atgccgatca
    25921 tatacgtgtt ttacacaagc atttgaatca gccttttatc gatacagtat tggtcaatac
    25981 ggaaaaagtg cctgaagatt atatggaccc agagatctat gatgagtatc tagtacaagt
    26041 cgcacacgac ttcaacggat tgagaaatga aggatgtcga gtgatttcca ccgacttttt
    26101 agaattgaaa gatggtggtg tcttccacga tggagacaaa gtagtagaag aattgttccg
    26161 tttagttttc ggttcaaaat attaagcaat ttattgttgg agaaaggagg agaataggat
    26221 gtcatttgct gcagatgtga agaaagaact aactggtttg gaagttcatc gagaacatgc
    26281 gaaagcggaa ttagctgctt tgctgcgaat gaacggctct ttaggtattg tgaaccagca
    26341 gtttattttg aacgtccaaa cagaaaatgc tgcaattgcc agacgtatct attctctttt
    26401 gaaagatcat tatcaggtac gaagtgagct actcgttcgt aaaaaaatga aattaaaaaa
    26461 gaacaatgtc tatatcgtcc ggttgaagca aggcacaaaa gatgtgttga tggatcttga
    26521 tatcatggat ggtatgatgt tcaatggaca cgtttcggac gagattatgg gaaattcgca
    26581 aaaaatgcgt tcttacttac gtggtgcttt tatggcctca ggttcagtca ataatccgga
    26641 aacgagtcgt tatcatttgg aaatattttc tatttatgaa cagcataacc aagacatttg
    26701 cgatatgtta aattattacg gtctacatgc tcgaacgctt gaacggcgca atggctatat
    26761 ttcgtattta aaaggagcag aaaaaattgc tgatttctta acattgattg gtgcaaccaa
    26821 ctcaatgctc cgatttgaag atgttcgaat cgtacgggat atgagaaatt cggtcaatcg
    26881 tctagtcaat tgtgagacag caaatctgaa caagacgatt gatgcggctt ctaaacaaat
    26941 cgaaaacatc gaattgatcg aagcaaaggt cggtctacat gcccttcctg aaaaacttca
    27001 ggaaatcgca gaacttcggc ttcaacatcc agaggtcagc ttgaaagaat taggggaaat
    27061 gattccctca ggtgcaatat caaaatcggg aattaatcac cgaattcgca aaataaatga
    27121 atttgcggaa aaactgcgtg aagaagcagt ttaatccaaa gaaaaaactg atacatgaag
    27181 caggagatgc gaatgtatca gtttttttta aaagctatac ttgcttttct tccgtcaaac
    27241 tataattcca actttactgg agtaacataa tgttgaaagg cttctattgt tttttaatac
    27301 aatcgtataa aaagcgggga gacaactgaa tgaagatttt agttttatac ataaactttt
    27361 gcttaatata gaagtcctga tatagatagg atcaagtatt tatctataac tggagattaa
    27421 ttaaaaactg gaaggaactg ctcgatcaac cttgagaact gtttttctta cttctggtca
    27481 agattctcgt ggttggtgga taaggatggt tgataagttc attggattag ctagtcgaaa
    27541 acaaccaggt gtaattaatg tagaagtttt aacaagggga tggagtgatt tattcagtga
    27601 taatcataag ttcataaata gtaattggga tgtatggttg gtatacgtta tacctgaact
    27661 tgaactatca agatttggtt tagaatttga gaatcgatgt ttataaaggg agggcaaaaa
    27721 atgtgctttt ttacaacttt tactatcatt atgattgcag tactttttat ttttctagat
    27781 atagcaaagc gaaatacagc atttttatta tatcgggttt tacttcgagc aggtctcata
    27841 acatttatat cgatcgttgg attttttcta ttcacagtta ttgtatttat ttggagaact
    27901 acagcaccac cattgccaga gattacatat ggagaatttc cgtttagtct tgaatatgaa
    27961 atagatgagg aaagaatttt gattgaagat acggtgattg cagaatttat aggaagtttt
    28021 agagggaatg tgacaactca acctagacga agttggagta taaaactttt aaataatagt
    28081 ggagagttga aagcatttca ttatgaattc ttaataatag aaagtgaaga tgtaacaatc
    28141 actttaagta gtggctctgc tggatatttt atgaatgatg gtggaagcaa gccacagctc
    28201 acagtccgtg atcgtattgc aggttttatg catttttctc actatgactt agaagaagct
    28261 cgtaaaatac ttgcagaata tgggatcaca ttaatcaatt gggaatatgc gccaccgata
    28321 agaaattttt tcaatgatta ttattagtct tataaaaaac agaatgtaaa atttatgtgc
    28381 gcgagtattt agttttccat tttttgtttg atagatatat agcattgttg aagcatggga
    28441 tagtggtgcc aattttatca atgaggttgg tcaggcagtt aacataattg gtgatgctat
    28501 aaatccattt aattggaatt ggaggaatta ggtgtggaaa cagtgagatt atggatattc
    28561 atgaaaaatt ttcgttcggc tttgagatat gttattctgg aatcaaaatc aggttattat
    28621 ctgattgaca cagatcacta tactttttgg ggaggctacc tttttccgat ttttaattgg
    28681 ataatccccc ataaggttat gaaaattaac ttgcctgcag aagaaataaa tagattaata
    28741 ctcaacaaag atttacaaag gaaaagagag aaagaacatt ctaatgttgc ttggataggt
    28801 ccagcatttg cagtagtgac ttcttcaatt gtcggtccta tgctagagag tatttatagt
    28861 gatttttcta ttggaatacg ttatttattt gttactttaa gtatagctgt tcttttgtgc
    28921 ataaagggtt atgttagcaa gaagaataaa gatattttaa cactaatcgg tgtaaacaat
    28981 ttatctagta ctaaaattat actgtttcct gaatctataa aagaaggatc aaggttgttg
    29041 ataattttta taatgcttat actgttttct gttttatttg gggtgatgtt tataga
//
LOCUS       DAFLWC010000030        27967 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.031, whole genome shotgun sequence.
ACCESSION   DAFLWC010000030 DAFLWC010000000
VERSION     DAFLWC010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27967
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.031"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(419..1363)
                     /locus_tag="L1V17_001207"
     CDS             complement(419..1363)
                     /locus_tag="L1V17_001207"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBN1235987.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(1659..2603)
                     /locus_tag="L1V17_001208"
     CDS             complement(1659..2603)
                     /locus_tag="L1V17_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1235988.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            2824..4038
                     /locus_tag="L1V17_001209"
     CDS             2824..4038
                     /locus_tag="L1V17_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1235989.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            4060..6075
                     /locus_tag="L1V17_001210"
     CDS             4060..6075
                     /locus_tag="L1V17_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HBN1235990.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(6158..7531)
                     /locus_tag="L1V17_001211"
     CDS             complement(6158..7531)
                     /locus_tag="L1V17_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBN1235991.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(7557..7841)
                     /locus_tag="L1V17_001212"
     CDS             complement(7557..7841)
                     /locus_tag="L1V17_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1235992.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(7843..9858)
                     /locus_tag="L1V17_001213"
     CDS             complement(7843..9858)
                     /locus_tag="L1V17_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBN1235993.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(10037..10342)
                     /locus_tag="L1V17_001214"
     CDS             complement(10037..10342)
                     /locus_tag="L1V17_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HBN1235994.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(10431..11462)
                     /locus_tag="L1V17_001215"
     CDS             complement(10431..11462)
                     /locus_tag="L1V17_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1235995.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            11669..12544
                     /locus_tag="L1V17_001216"
     CDS             11669..12544
                     /locus_tag="L1V17_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBN1235996.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(12696..13538)
                     /locus_tag="L1V17_001217"
     CDS             complement(12696..13538)
                     /locus_tag="L1V17_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBN1235997.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(13630..15507)
                     /locus_tag="L1V17_001218"
     CDS             complement(13630..15507)
                     /locus_tag="L1V17_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBN1235998.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(15504..16925)
                     /locus_tag="L1V17_001219"
     CDS             complement(15504..16925)
                     /locus_tag="L1V17_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBN1235999.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(16928..20317)
                     /locus_tag="L1V17_001220"
     CDS             complement(16928..20317)
                     /locus_tag="L1V17_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBN1236000.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            20574..21965
                     /locus_tag="L1V17_001221"
     CDS             20574..21965
                     /locus_tag="L1V17_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1236001.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(22038..22685)
                     /locus_tag="L1V17_001222"
     CDS             complement(22038..22685)
                     /locus_tag="L1V17_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBN1236002.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(22693..23379)
                     /locus_tag="L1V17_001223"
     CDS             complement(22693..23379)
                     /locus_tag="L1V17_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1236003.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(23385..24458)
                     /locus_tag="L1V17_001224"
     CDS             complement(23385..24458)
                     /locus_tag="L1V17_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1236004.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            24680..25354
                     /locus_tag="L1V17_001225"
     CDS             24680..25354
                     /locus_tag="L1V17_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1236005.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            25359..26699
                     /locus_tag="L1V17_001226"
     CDS             25359..26699
                     /locus_tag="L1V17_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBN1236006.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(26848..27834)
                     /locus_tag="L1V17_001227"
     CDS             complement(26848..27834)
                     /locus_tag="L1V17_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HBN1236007.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
BASE COUNT         8164 a         5274 c         5063 g         9466 t
ORIGIN      
        1 tgataaacct ctctcgaacg gttttttatc aaaaatcgtc atttttccat caaaatctgc
       61 ttatgcaaaa ttataaaaaa attttgcagt ttttcttact ttttttgtcg tttaattgaa
      121 tgataaaaac cagtttcttt attcagttaa tcaaatatga acgaattaga tatgaatcat
      181 tgtatttgcc gttgcggaag gattttttaa ttaaccacag ataaacattg ataacgattc
      241 gcttattgta atcaacagat taaatttcat atgttcatat gtacggatac attttcggac
      301 cgattaattt taaccattct atttatttgc ttacctatta gatatcaata aaaaactgct
      361 taacagctat ttcagctgtt aagcagtttt aggattttta gttcatattc attgtttctt
      421 ataatacagt gttcaatact tctcttaaag cacttgttga tttgctgaac attgcttttt
      481 cttcttcgtt gattgataat tcaacaactt cacgaacacc attttcgtca acgattgatg
      541 gcacacctgt aaagatatct ttttcgtcgt attcaccagt taaataagca gatacaggca
      601 atacagcttg ttcgttattc aagatagctt ttacgatacg tgcagtactc ataccaatac
      661 catagtaagt tgctttttta cgatcaatga tctcataagc agcattacgg actttatcag
      721 caatcacatc taattcatct tgggcaatac gatggtcttt ttctacaatt tcaaacactg
      781 gtttaccacc gacagttgta tgtgaccatg cagcaacttc tgaatcacca tgttcaccta
      841 agatatagcc gtggacgctg cgtgggtcaa cttttaattt caatgcgatt tctttacgga
      901 aacgagttgt atccaatgtt gttccagtac cgataacacg tgatgttggc agaccagatt
      961 cgttccaagc gatatatgtc aaaatatcta ctgggtttga agcaacaacg ataataccgt
     1021 cgaatcctga tcccatgatt tcttttacga tttggcgcat gattgacgca tttgttttaa
     1081 ctaaatctaa acgagattga ccaggttttt ggttgatacc agctgtgata acaacgatat
     1141 cagcatcttt acattcttca tagccacctg accatacagc cacattttca tcgccccaag
     1201 ccataccatc taaaaggtcc aatgcttccc cttctgcttt ttcttgattc acatcgatca
     1261 atactaattc attagagatt ccttggttga tcattgcata agcgatactt gttccaacaa
     1321 aacctgtacc gacgattact actttacgac ttgttttttt catgaataaa cagctccttt
     1381 tcataactat ttgttacttt catgaaaagt atagtcttgt ttattcattt tatcaacatg
     1441 ttaattataa tagttgttat tataattttt gatggaaacg aattcctgaa tacgcataac
     1501 agataaatga caaatgttta cacctatatc ccctgataat acaaccaaaa gtttagaact
     1561 gaaaataaat ccaaaaaaat tcgctgcaac gatataataa gacagcaatc gcacctaaaa
     1621 caattttcct tcatatgctt tagtgaaaga ttttcttctt aatgtttatt tctccattca
     1681 ttgggagtac atgttgaata cttcttgaat aatttgaata aagaagtcgt ttgtttatat
     1741 ccgatacgat tagcgatttc ttccaacgaa aaactcgttt cttgaatcag ttccaacgca
     1801 aagtcgaatt ttttctttag aaccagttct tgaaaggaag catcaaaata cattttcaat
     1861 ttattactaa gatagaccgg attgtagcca aaatgagctg ctgtttcttt taacgtacaa
     1921 gaagtaaaat gcttatcgat ataatctaat actctaagca tctcattttc tgcgcatcca
     1981 tctgctgatg aaaagctttg ttgttctaat aaatgagtca attcgatcag taatagtgat
     2041 gtatagagat ttaacgaacg gatcttatga ctgtatgtat caaaataaat caacagcata
     2101 ttttcaatca aatgcgtcaa acgacttgtt tttccgccgc gaaaatgaat gaattgtgta
     2161 tgttcccctt tttcttttga tgcatttatc aaaaaagaag aaagtagatt atttgtgctt
     2221 gccaaatgat tcaatatctc tgtagataag gtttcttctt ttaataagat gttgattaaa
     2281 atatcctctt gccctgtgta ttcgattctt tgagtagctt ctttatcaat gatcaccacg
     2341 tcactttctt ccatctctat cctttctcca ttaataattt gtaaacatgt accgctatac
     2401 atataattga tttcaacaaa atcatgtgta tgctcgggaa cttccgcata tcgacggtgt
     2461 ttactgatat gaatatttcc ctgttgaaat agatcccctc ggtggatttt tggcggtgtc
     2521 tgaagatggt aagctaagtt taaatcattg atattcattc cttgttcacg ctgcagagtt
     2581 tcgattgatt cttcgttacg caaaaaaaat gtctaattca gctagttcca attgactccc
     2641 tcctttttgt aagcggtttc tttcgcttat tagttcacgc tgtactgcta ttatatgcaa
     2701 agctattttt ggtttcataa agactttcta tggttgggac atgaacttcc tgtgattccg
     2761 ctattgagag aataaccact tcatactata tttttgataa gcgcttacaa aaatgaaagg
     2821 aacatgctta tgaataaaaa gatgatgaaa ttttctctgc tgtcagtctc tcttattttg
     2881 acttctgctg gtgcagtcac gtctgcaatt cccagtatgt cagctactta tgccacgcgt
     2941 tctttatctg ctgttgaatt attaacgact gctccctctt ttatggtcac tatttttgtt
     3001 ttgattagta gttttattgc taggaaaatc ggacaaaaac aaactgtgat catcggatta
     3061 gtgattgcat cgatttgtgg tatcctcccc ctcttctcac aaagttacag tattgtctta
     3121 gcttcaagag ctggactagg tattggcttt ggattgatca attctttggc agtcagcatg
     3181 attgctgcct tttatcacgg agatgaacga gcctctatga ttggttttca aagtgcattt
     3241 caaggatttg gtgcagcttt aatgacattt gttgcaggac agctagtaca gttcggttgg
     3301 caatatacct ttttagtcta cgccatcagc ttacctattc ttgtcttgtt tgttttgttt
     3361 gttcctacac ctgaaacaac tgaacttcaa tcgcatggca cagccccaac aagacaagta
     3421 atcaaaacga atcctaaaat gattagttat ggtatttttc tcttgctggt catcgtggta
     3481 tataatgctg tatcgattaa attagccaca gtcctgacga cttattctct aggaaacgaa
     3541 actaatgcag cgaatatctt aacaatcatg caattggcaa gtatggctgc cggagtttgt
     3601 tttggctggc ttcagacaaa agcacatcgc tatatgctta cactttcttt actactgatg
     3661 ggaatcggct ttgtattgat tgccactgtg ataaacctgt atgtgattgg gtttggtgcg
     3721 atcctaacag gaatttcttt ttcgttattc attccttact tattcaacca agtaagtatc
     3781 caagcgccca agtacgcgga gagtttcaat acttcaatct tattggttgg cgctaattta
     3841 ggtactttca ttgcaccata tggtttgctc tttctctctt ttgcttctct tgggagtaaa
     3901 acacttgctg ttttcgtcaa tggcagtatc ttgctgttga ttagcgcgct tattagcctt
     3961 ctagtagtac acaggacgaa tagaaagaca gtgataagag tagatgaaga aataaaagaa
     4021 caattgacaa caaaataaat ttgatggagg tcgtgtaaaa tgacaaatga aaaacataaa
     4081 gatagatggc tttggtatcc tggagacttt gagatccgcc atggactgct acaaaatttc
     4141 caacgggaag aacgaggttt tgactggcca gcgtactggt acatggatga ttgccatcgg
     4201 aacgtcaagt ttaagagata ttactttctt gatcaacctt ccatgtttaa agtgacgatc
     4261 caaggagttg ggtatgtaga aattaatgga caaaaacatc catgtggaaa atggctgact
     4321 tgtccagctg gtaaagcaaa aattcgtatc tttgtaggac atacatcagg gctaccagcg
     4381 atgtttatcg agggagacga agtaaaatca gatattggct ggacagcaag taattttatt
     4441 gaagaatatc cagctggctg gagtccgctt tatgtcgata tcgcaaaaga tccaaatcaa
     4501 atctattatc aaaaagaatg cgtccatcca gtcactgaaa cggagattgg cggaggaatc
     4561 ttattcgatt ttgggcgagc agtgaatggc tgtgtagaac taatatctct ggatgaccat
     4621 atcgaatcta tcactctatg ttatggagag tccgatgtag aagctatgga tatcgattat
     4681 tgctactata agcaaatagg aatgacaaga aaaatgaaag ctcgtaaacg cgcttttcgc
     4741 tatttgttta taccagaggt ttctactgga atggttcaac ttcaagtttt tcatgaattt
     4801 ttatctcttt cgaaacaagc tgctttttca agcgattctt ctttactgaa tcagatctgg
     4861 tcagtatcag aagaagcctt caagttatgt agtgatttgt tttttatcga cggtatcaaa
     4921 cgagatcgct ggatttggtc tggagatgcg tatcaatcat tcatgatcaa tcaatatctt
     4981 ttttttgacg aggaaatcaa taaacgaacg atattagcat taagaggaca aaatgaaatc
     5041 aagcagcata tgaatactat cgttgactat tcgatcttgt ggttgattgg tatcgaaaac
     5101 cactatatga tgacgaaaga ctatgaattt ttacgcatcg tctaccctaa gatgcaatca
     5161 ttaatgagat acttgatgga gcaaacgaat gaattagggt ttatttatgg gagagcaaaa
     5221 gattggatat ttattgattg gtctgaaatg gataaagaag gaacgcttgc tgcagaacaa
     5281 gtcttattac tgaaagccta tcattccatg atcacttgcg gagatatctt agctgaaaca
     5341 tatggagaga acgaaaatta tcatactcat ctctatcaag aaaaatatca actattgaaa
     5401 caaaacctat ttgactactt ttgggatgaa gaacttggcg cttttatcga ttgctatgaa
     5461 tctgggagaa gaaatgtgac gcgtcatgcg aatattttcg ctgttttatt cgattttgct
     5521 aacaaagacc aacagcaatc gatcttaaag aatgtcttat tgaatgacac tatcacacag
     5581 attactactc catatttcaa attctatgaa caagatgctt tatgcaaact cggacagacg
     5641 aatatcgtct accaaacgat tcttgattat tggggaggga tgttatctca tgatgcggta
     5701 actttctggg aagaatacga ccctactcaa acaggaaatg aaaagtacag tatgtatgga
     5761 gatccttatg gaaaaagctt atgccatgca tggggagcaa gcccaatcta tcttttagga
     5821 cgctatttta tcggtttgta tccaacaaag ccaggttatg aagaatttat gatacaacct
     5881 aatctagatt catttgaaac actgaattgt acgctaccta tcaaagatgg aaagatttcg
     5941 cttgaaaaaa caaaagataa gatcgtgatt acttctgata gaacaggcgg aacagtgaaa
     6001 atgaatggta aaagttatcc tcttctagca aaacagccac ttgtcttaac aagctattca
     6061 aaaataaatg cataaaacaa aaaactgctt gcgacatatc agaagacttt aaatcttctt
     6121 ctgatattgt ccaagcaatt tttattttga agtttgctta attctgttct ttagaaacaa
     6181 tgtttgttct ttttccggca aaaagaaagc tagataatac gacaagtaaa aagaaagcga
     6241 tgattccaac tgtcaaggct atttgaccgt attctcctag tttcccaagt acaagtcctg
     6301 gtactagata atcagtatcg gcaaatgtag aagaagcgat tttaagatct cctaatactg
     6361 gaaggataaa taatggcagc caactaatca ataagctatt gaaagcagaa cctaataccg
     6421 cccctcttct accgccagtc gagttgccga agacaccaga agcagctccg cagaagaaat
     6481 gtcctactac cccaggaatg ataactgtag tttgcaagcc tatcatagca aacatggata
     6541 gtgttcctac aaagaagcta acaaaaaagc caattaatac agcattaggt gcatatggaa
     6601 aaacgatagg aacatctaat gctggtttag aatcgggtac gagtttttta gcaatccctt
     6661 ggaatgctgg aacgatttct gccaacacca ttcgaacccc ttgaaggacg ataacaaacc
     6721 cagctgtgaa tgttccagct tggatcagtg caaagattac agcgttgtct ccattgctta
     6781 gttctctttc aacaaatcca ggaccagcta acaaagcaag tgcgacatat acgatcgaca
     6841 tcaagagcat gatcgataca gtagaatctc gcaaaaagct gaaactttta ggaatcttta
     6901 tgtcctctgt agaacggtct ttgtttccaa aaaactttcc gatccatcca ctagaagcat
     6961 aaccgatatt tccggtatgc cctaacgcaa cttgattgtt tccagtgatg ttcttcataa
     7021 acggttgaca aagagcaggc gtaatagtta atagtgttcc ttcgaagacc ccgcctaata
     7081 agatcatcca caaatttgca gtaaaccccg cgcttactaa aatgactgct gttagacaag
     7141 aaacataaag cattgcttga cctgtaagaa aaatgaattt atatcttgtg aatctagcaa
     7201 gtaaaatatt cacgatcatc cctactagca tgatcaaagc agtaggtgta ccgtattgtt
     7261 gcaaagcaat cgccactact gcttcattgc taggaactac tccttgagta tgcagagctg
     7321 tttggaacat cgaagcaaaa ggggttagtg aattactgat taaaccagca ccgccgatca
     7381 gtactaggaa tccgacaaat gttttgatag ttccttggat cacttctgaa aatttcttct
     7441 tctgaagaac gagaccaagc agtgcaatca aagaaacgag gatggagggc tgactgacga
     7501 ttgacacaaa caaattcaac aatttatcca ttgatagttc ctcccttgaa tcatttttat
     7561 tcttttgaca agatcttcgt tactttttct tttacttctt cgctgtcaat gatcgattgc
     7621 aaaggtacga gcttttcatc aggtatagaa gttagcgtat ctttcaaaga atgctcaatg
     7681 aagaaataat cagccatatc gctagataca cttccaacat ccgtatgact tacttcaaac
     7741 tcgtccacat ctgctccaag atctgcaagt gcttgtttga tgttcatctc taccataaaa
     7801 cttgttccta atccactttg acatactgca aaaattttca tatcattcgt ctccttttct
     7861 tatgatcgct aatatttctt cttttgttga tgcgtgtaat aaatcttgaa gattttgttt
     7921 attagaaagt agctttgtta aatttgccaa agcccgaaga tgtgcctcat tatcgatagc
     7981 agctaaacag atgaacaaac taatgggatg ggctggatta tcaagcagat ccacaggttg
     8041 ttgaagtttc agcaaagaca tccctacttc gtttacgcca tcttctggac gagcatgagg
     8101 taatgcgatg tgatcgccaa tatggataaa cgcaccatac tgctccacgc gctcgatcat
     8161 agctttgata taactttctt ctattttatt ttctgataat agcggctgtg cggcaaatgt
     8221 gattgcttct tgccagtttt ttggttgatc cgataattgg atcatttctt ctgttaataa
     8281 ttcagatagc ataggacgtt gatcctcctt cttttctaaa agtttgttca ttttacgatt
     8341 taatacttga tagagctttt cttcgtctac gccttctttt aattcgatat aaggcagtag
     8401 cgccgacaac aattcttggg cagaaggcat tgaaaatcct ggtatcagcc aatctctttg
     8461 tacttgattg atcagctgat ttttttccaa gtcagtcatg attggatgca gaacatagag
     8521 agactttttc ttatcagtaa gtgtgagagg tacagtagaa aaaataatat cgtaagaagt
     8581 ttcgtcaacc tcgtgtaagc ggtcagctga attagtctct gtaaaaaaga tcatcgggaa
     8641 taattgctga agttcacttt ttaagatcaa tgaagagcta atgccacttg gacagacgat
     8701 cacggctctt atttttctat ttctttcttc tgcgtccgct tttctgatct ctccgccaaa
     8761 tagtatagtg aaaaaaccaa tctcttcttc agggatgctc ttccctattc gtctttctaa
     8821 cggaagtaat gcttttcttg tcatttcgta gatggaagca tattgatgct taatttgatc
     8881 gatcatcaca ttaggtaaat aaaaagaata ggaaatacga aaataggcag ggaccaagtg
     8941 ataaaagaca ttcatcaata attcacgaaa cgaagcaaat tctacggcca tcaggaattc
     9001 catgcgatgg atgacttctg aagaacattc cagcaaaaaa tcaagtgcag gctcctggac
     9061 atctccttca acgatcgatg ctaagcaaag agagaaaaat ataatctccg aattttgatg
     9121 ttcggaatag ccaaggccag tcaatacttg tcgactaatg tcagtgactg caagagaagc
     9181 caacagttca gcatctttta ccagttccat ggatgttttt ccaattcgaa tggttgtcaa
     9241 actcaaataa taagctaatt catccattcg atttggtgcg aatcgaagat ctgatagtga
     9301 aatcgtttta tctagcaaat ctctaacttt ggcgtaataa tcaatggaaa gggttgcggt
     9361 taaatacgtg agcccaaatc ttccagcaag tgactgcatc aaacgagcag tgcgattttt
     9421 tgcttctctt cttaatattg cttctgaccc tagcagccta aaaccagttt tcctagtata
     9481 cgacagctga caatcttcca cttctaattc atttcttatc tttttgatat ctgacaggac
     9541 tgtcccttta gaaacctgaa gaaaatcttg aaaatgaaaa acagaaacag acgttgcagt
     9601 cgaataaacc atcaaataaa gaagatctct tcgctcttgt tcggtataca cagcttcaaa
     9661 tcgagtaata tccaaaaatt tttctgccca gtcgattgct cggaatttct ttatacggat
     9721 acgggtatca tccacatatt cggcaaaagg agttaattgt ttgatcgcct cgcttgtatt
     9781 tacttcgatg atctctgctg ctttttctag actgatttct cttggtgttt tcaggagata
     9841 actaattttg tagttcacag cgctgttcac ctcctactta tattctagta tggtagcgct
     9901 tttaaatcga ggggtgtttg gtacaactta cagttggatt ttttttacga ctgtaccgaa
     9961 cgatttctat cgaatggata cagaaaaaaa gcaggtgacc aaatgtctcc tgcttttatg
    10021 aattgatttc gtccgatcaa tgatgatcat gtttattttt tgaggtcagt tcttcaaatt
    10081 tttctttgac atcttcaacc gctttttcga tatctttttc aaagtgattg ggctcattag
    10141 gctttgtttc ctcttctaca gaatttgaac cagataaagc tgtttcttta ttttctgttt
    10201 caccagagtt tgtgccagct aatgattctt ctttgtcttc tgtttcacca gaattagttc
    10261 ctgctaaagc cacttcttct tctgttttag gggccattga acctcttaat cgtttgtgtt
    10321 tttcaccgtc ataatttgtc atgttggttc ctcctagtag ttctatactt tttcatcgta
    10381 caataagaca gtttatgcgt caaaaaacaa acccgattct tacaaatatg tcatattttt
    10441 ccttctgatt cttgaatgct tttgattcct tcttccaaaa ttttcatttg taagattgtt
    10501 tcttcatctt tgatgacttt ttctgcgcca ttaactaatg tctcgtaaat cccttcgtag
    10561 acacggctgt aatcaccaac ctcggaaatt actttttctt catgataact cccttgttca
    10621 tctatatagg tcaatacacc ataatgttcg ggcaaatcga taccaaagtc ttcatgatca
    10681 ggcatgtaaa acattttcag atgttcttct tgtcgatctt ttgtttgttt cacgaacatc
    10741 cctttttttc cgtaaacgac gaaacttgga cgttctttga tgcggaaata actggatttt
    10801 atcgaaattt tcatatttcc atagaaaaaa tccagatcga agtaatcatt cattcgtcct
    10861 ttccctaaaa gttgacgtac atcatagctg atatcatctg gttcgccgaa ataagaaaga
    10921 acttgatcta ctgtatgaca agcatgtcca tataaatagc tgttcgcagt agaaaattca
    10981 tgcgtatttt ctggtacttc cggtctgaaa taatcataat gcatttctac ttctaaaata
    11041 tcccctaatt ttccgctttc gattactttt tggactgtca agaagtcaga atcgaaccgt
    11101 ctgttttggt aacattggat aaatagacct ttttcttttg ctaatgcaaa taactcttct
    11161 gcttcctttg acgtttctgc aaaaggtttc tctactagta cattcttacc atgttcgagt
    11221 gccatttttc catattcata atgaaattga ctaggtgtag tgatgacaac taattggatc
    11281 tcaggatcat cccaaagatc agacagctga tcagtatatt cgatgtcttc gaatgttttc
    11341 cacactggtt cagatgggga aaaaattttt ttgatattga ttttgttcgt aagttttctt
    11401 gaaaaaggca aatgatagcg atttgtactc tttccattgc caagataagc gattgtaagc
    11461 atgagtggtg cctcctttta ttgatgtttt cagtatatcc tagaaaagcg cagaaagtat
    11521 ttataatagc tattctggta aaaaagttca gaaaaacact tgttatcatt cggtttggtg
    11581 aaattaatgt tcaaagtaag gataaaaatc aaaaagatag tagcggaacc aagtgtttat
    11641 cagtaagata gaatttggag gtcagatcat gcttattgaa gaaaaactaa caaaacaaga
    11701 gttgtttacc acgacagaga aacggattgt cgattacatc cgtaggaata tcgaagctgc
    11761 agtctacatg acgattgaag aattagcaaa agctacgtat acttcccatt cagctatcat
    11821 tcgtttatgc aaaaaaatgg gattcagcgg atttaaagaa ttccgtttcg agctggggcg
    11881 ggaagttcat caattgattg ctcagttcaa tcaaacgatt gatcctaatt ttcctttttc
    11941 aagtgaagat agcactcagc aaattgcaaa gaaaatggcg gatttatcga tccagtcaat
    12001 aaaaaaagca caattgcaga ttgaacatga agatttagat caaatcggta aagtattgaa
    12061 caaggcacag cgaatctttc tttttgcaaa aggtgattct caaatcacgg caaggaaatt
    12121 ccagaataaa atggtcaagt tgaataagtt tttgatcatg gctgaagaat acagtgattc
    12181 ttcttggaat gcagccaatt tgactagcga ggattgcgcc atttttatta gctacagcgg
    12241 tcgcatccat cattatgaac gaataatgac ctatttgaag catgtagagg cccctacctt
    12301 gctgattacc ggaaatcagc attcagaaat ggccaaacag gctgatatgt gtcttgttat
    12361 atcgcaggag gaatatgatt ttgctaaagt agcgactttc tcctctcaaa ttgccttcga
    12421 ttacgtatta aatacgttat tctcagtgat atattctcaa aattttgaag agaatatccg
    12481 caacttgaaa aacaaacaag aattgatgca aaaaggcctt cttaaagaat atcggaaaac
    12541 ttaagaaaag atcctcattt agtaataaga aagatagtgt ttgataggct ctctttgata
    12601 tcatcataaa aacaggctga agttttcttt ttcaaacctc agcctgtttg tttacggaac
    12661 gattcgaata gatatattat agaaatgagg aatagctaac ttctgtttct tattttgaac
    12721 gattgacgaa aaagatatat aagaaggagg aaaatcagta tacatgcagc taacaatcca
    12781 tacaggaaaa atcgtttgtt ctcggatact ttctgtactt ctttttgaac ttcttttgca
    12841 tgataaggaa cccggtgccc tctgacaagt aagcgatgac tgttgaccat ataaggtgta
    12901 caagttagga gtgtcacgaa atcctgccct ttttcgattc tcagatcttt tgtatcagtc
    12961 ggttctaccg tcttgatctg atcgacttga taagcgagtg tccgtccatt gatttcgata
    13021 tagaaagaat cacctaaagt cagtttcggt aagtctgtga acaactttgc ttgaggcagt
    13081 cctcgatggc tggaaataac ggcatgtgta ttttctcccc ccgtaggata agacgttcct
    13141 tccaataatg aggcaccttt ttctagcagc acagtattcg tttcatcaaa aattggcaaa
    13201 tggacattga tctcagggat cgtcaaaata ccgatcgtat gtttctcaaa ataggttcta
    13261 tcctttttcg caggttcttt tttcttagta aagggatctg cacctggatt tccaccttct
    13321 tttgctaatt gctggttttt ctttgtcatg ttttcttgga ttttagccat gacttcttca
    13381 ttttctttga ccgcttgttg ctgataatga gagatgatct gctgatccag ataattattc
    13441 agcgcgtcgc taacaaatgg ataagctagt atccctattc ctgagagaag caagaaaagc
    13501 atcagcagat ctagaagttt ccttttcttt ggtttcattt gtgttctcct tgtgatgact
    13561 gtttgataat aaaagaaaaa ggagcatttg cgtaatccgc tgctcctttt tccaattctt
    13621 gcaaaaagac taaatctgac tgtgcttgcg tctagcaaag tacagtccag caatcagtag
    13681 aaggactact cctgcaccga tatacacata gattccctta ccgcctgttg aaggaagtgt
    13741 acctttgtgt ttatttggta ttttttcagg agaaatcaac tgtcctgctg ttacataaga
    13801 ttgttcatcg atagtaaatg ctacacggtt tgttaatgga acatattttt ctggcgcttt
    13861 cgtttcttcc agatagtacg tgccatattt tagacctgtc acatcgatta aaccgttact
    13921 tgtggttgta aaaaccgttg ctgattcttt cgccgatacc cagctgacgg cttttgtgga
    13981 tgggtcgatc gataaatatt tcgctgtgtc actatcttga tcacgaacga cgaattctgc
    14041 tccagcaagt gtttggtctg atgtaacgtc accatctact ttaacaaatc gtttgccccc
    14101 agtaacgaca tcgactgacg gtggtgtttg atcatttgta tgcccgttat cgacatttgc
    14161 ttggttagaa aatcctttgg ttggatctgc tttttcgttc aaatgcatat agtaaacgaa
    14221 tttcaatgta ccgccaggag ttaatgaagg aatataattc ggatcaactg aaaccgtgaa
    14281 tccgtctgtt tgctcagtga cagaataatt tactgggtcg atttctttat ttccatcata
    14341 taaggcataa gcatacgttc ctgaagaatc attatcaaat gttaaagcag cgtcatgagt
    14401 atcgataagt ttgaatgttg tgtacttgtt ttgcgttcct tctttatcag cgatacctaa
    14461 tgggatattg acagaaatct catattgaat tttttcaccg attgcgacat cttttccatt
    14521 caattgaggt gttgttttat caactttaga cgtatcattt ttgatggtct tttctactgg
    14581 tgtttggcta tttgccagga tctcaaaagg cgtgattgtt tgcttttcaa tcatttccgc
    14641 attatcagga gcttttactt cttctaaatt atattttcca acttctaaat gattaacgat
    14701 caactggcct ttttcaatag atgcctcggc aaagtcattg ttgccgatgt cataagaatg
    14761 accagtaatg aaatgtttgg ctttggtttg atcagttgtc caagtgtaca atccatctgt
    14821 gacactttgg atgtattttt tgacgcttgg tgttccttct tctttagaaa taataaattc
    14881 tgctccattt agtgcttcgt tttcggcagt accgattttt gtaactttca acgttccatc
    14941 attaccgact gtatttttag ggtagagatg gatagtatct agttcttctg tcccgtattt
    15001 ataagagcca tctgcttgtt tgatcatctc atatacaggg aaagctaaaa ccatgtttgc
    15061 ggcagctgac actccgtctt ttggttcttc tttgatcgtg tagactgcat ctttcccatt
    15121 ttgtttttta ggtaaagata aagtgacatt tccatcagca tctgtcgttc ctgaagcaac
    15181 tggtgtacca ggagtcaaag actggactgc ttgttttgct gcatccacgg acgctccttt
    15241 atctcgttgc gcataaaatt cttgagtgac gttataaact gaaaatgaaa tatcggctaa
    15301 tccttggtat tgatcgaatt cgctcatttc tttcccgctg ttttggatta aaggatcggg
    15361 taaatcagtc attttctttt tatgaaggat gacttgagct gctgtctcct ctgcaaacac
    15421 tttttttgcg ccgaagctgt ttgtgagtaa tggtaaaata aggaaaagga ctcctaacat
    15481 aacgtttatt tttttatgat ttttcatttt ttcactcctg ttcttttttt gataaacaac
    15541 cagattgcaa agcttgcgaa taccatacca acaacgccta aaagtgtatt tttcgtttcg
    15601 tttgtttttg gaagaaatgg acggctattt tcttttttat tgactacttt caatatactg
    15661 tccgcctctt tatcctcaga aagaaaagtt gaaatggtaa acggaatttc tgtttcactt
    15721 aaaatataac cagaaggtgc ttcgatctct tttaatcgat aacttcctgt tttcaacccg
    15781 gaaattgaaa aagcgccatt tttatcggaa atcaggtgaa gcgcatctga ttcgttcttt
    15841 gtccacttgt atccgttggc tgtttgctgg aggtaatttc ctgctttgtt tttaataagg
    15901 aatactgcgc cagctaatcg tttatctggt ttatttgtct cgattttgac aaattgctta
    15961 ctccctgtat atacagagac tttctttgta ctgacaccaa aaccaaaatc cagtgttccg
    16021 ttgttgttga tttccttgtt cgcctgtgct gtactgctta gctgcatctg ataagaaatg
    16081 gtcagttttt ttccagcata tttttccaac gaagggatcg aaaataaaac atcaaatccg
    16141 tgaggtttct tgtgtatgac aaagccttct gtcagctttt ctccattcga tgaaatcgtt
    16201 aaactattag gtaaaaacgt taatgcttca tccgcactat ctgacaattc gaacttttga
    16261 tagtcaagga tatttacagg aattgtcgta tgcaaggaat aagtgatttt ttcaccaatc
    16321 gtaaaatcat ttctaggctc ttctaatacc ttctcaaaag gtggatcagg gtagtcgttt
    16381 tcttcatttt taggatacaa atggatagtt gaaagttttt gattgttttg tccatgtaca
    16441 ggaagaacaa ctaccatatt ctctgccttt tctttgacga cttctggtac tttggattca
    16501 atgaaaagat acgctttatc tcttttttct tgatctttag cggccagaga aaaagaagcg
    16561 ataccatctt cgttgttaag agttgtagtt gttgcttctg cggtaaacat accggaagac
    16621 gcaccgtttt ttgcgatctc tgcttgtgct tcttctaccg ttttgccctt ttcccgtaga
    16681 tggtaaaaag aatctgtgac atcataaact tggaatgtga caccatttaa tcctcgatac
    16741 gtttgtaata aagctttttc ttgtccgtca tttggatgat ttttcggcag ttgcccgttt
    16801 gggaaaagca atttgtgtaa agtaatctga accatttctg tttctgtttc tgttgctacc
    16861 tgagtaaaag ctggtttaaa tagtaacaag aagagacaca tactaagcca accaagtttt
    16921 ttcatattta gctgccccct ctttcttttt tcaaaaaaag ataccaaata gaaaacgcac
    16981 aaccaatcat ccctactaga tagattccta aacggccaat tcctcccgtt tcaggtaatg
    17041 gtacttttgc ctgattcgtg atgtctaaag aaatctggtt gtttttggct cctggtgaca
    17101 gaacagattc atgatcttgt ccatccactt gaattgaccc atcttcgtgt ataactatag
    17161 taactggctc ttttagacct tggtatcctt ctggtgtaaa agtttcggtc agcgtataag
    17221 ttccaggttt taaattttcg aatagaaagg tatctgtttc ttgtccatct tttggcgatt
    17281 ctaagtccat ttctggtccc tgcagtctga attttgctcc ttttaatgtc tgtccgttgt
    17341 cttctttttt gtgtaccgtt agatcaaacg cttttagtcg attttgatga gtgagcgtcc
    17401 atacattatt tgtcatctcg gtattttttc ccgtgtaaat gatttttcca tatttatcga
    17461 tttggaattc ataatttccc ggcgaagtat catatccggc aggaccagct gtttcaacga
    17521 ctcgatattt accaggtgtg agtgaatcaa aactggcaag acctttttca ttcgttgttt
    17581 ggctgtcaat tggctgataa gtaccatttg cttctttttt ctgtagggaa aatgctgctc
    17641 ctttaagatt tatctctttg tccgtccctt gcatcgcata cttacgtact gctacaggaa
    17701 cttcaacaaa aggattttca atagtcaact ggatcgtatc atcggaagta gtgactgttt
    17761 ttccatcaat ggttaccgta ccatcagaag cgatcttgat ttcccaagta gtctttttgc
    17821 ttaatccatg cccttctgga gcttttgttt ctgtcagcgt ataggtcatt tctttttgca
    17881 atttgacatt ttctggaaga gaataggttc cgtcgccatg atctgttagt aaagtatcaa
    17941 tagaatctcc tgttaatttg aaaacagcgc caataagatc cttttcacct gtagaggaat
    18001 ttttcgttat tttcaagttt aacggtgtga attgtttagt atttttccat gtcattgcat
    18061 ctatttgttg agaatcgtat cctggtacag gtaattcttt gattgtttgg taactgaatg
    18121 cttgaccttg attattgtat tgaggtagtg ataatatctc ttgataactt tctccgctat
    18181 ttgcagataa tttgtcaatg tctgcacgtt cccacgtatt tgttgtatct ttagctggtt
    18241 taatgattcg aatatatccg tttttccaag ctgcagcatt tgtcgtatgt tcccgttgaa
    18301 tctcaaaagt aacttgatct ggacgatcag ctagattgtt gtcaaattct tcccataact
    18361 ttttgatgtg aagactgact ccgggagctt tagcagatgg tataccgaat tcagctaatt
    18421 cattggtatc aatgtttggc tggaaagttg tcctgccgtt catttgatac cagaaatttg
    18481 gatggaagtc ctcattttct gtttggattc tcacttggta atggatttgg atttcttggt
    18541 cttttcctaa atagatctga ttgctcttga tggtatttcc ttctatggaa atagatggag
    18601 tgaccgttgt aggacttgtc cccacactct tgactgaaag tgtaccaggc tgataaatga
    18661 atggttctgc gattggatca tttatttgtc cattgcttac agttgctgag atctgtacag
    18721 cttttttggc taggtattca gagatatctg ttgcatgatc agctgattca tagtaaagat
    18781 cgcctttttc atctgatgaa accatttgtc gcatacgaga ctctacttct gcttttgaga
    18841 gaccagctgc cggatcgctt tgaagttgga tgccaagacc atgtatttcg attcctcgtt
    18901 ctttgagtgc catcgcttct ccgatggttg cgataaacgt actgtcgatt cttctggata
    18961 gattgttttg gtcaggtgca tcatagattc ttgagattag agaagtattt cccggccgat
    19021 cttgcgtatt agaaaactga gttccgtaat aattgctgct tgattgtgcg tgtacccgct
    19081 gtactttata ggaaaatgtt ggtacaccat ccgtcagcaa aacgatcact tttttatgtc
    19141 catttggaac ggatagcatg cttcctgcat ctcttagtgc tttttgtgta aaagtaccac
    19201 catttgtccg tgaaggtgta atggatttta cttgattttt cactgaatca aatgaaccca
    19261 tctgtactgc accgttactg tagctatatc cttcgcttga gtagccgaca tatcccatat
    19321 tgattttgtc tgtgataccg ctatctgcta aagtatcgac aaaacgatcg acaccaatct
    19381 ttacttcacc gatccgatta ttgtcgttca tacttcctga ccagtctacg accaatacga
    19441 gatcaagagg cgtgatatct ttttgtacat ttccacgagc attcaaataa acatcaaaca
    19501 atccgggtgt acttgtttcc tttgcatact ttcgtatcgc atagtctgct tgattaccgg
    19561 ttcctccata ttcgatatac gaatgggtcc gatcattagg atctccattc caagaattta
    19621 taccatccca ttgatttgtt ccgtttttat tgccttgatg atcaagaaca tttgtatttc
    19681 ctgtaggttg ccaactggct ttaggataag tgccctgatc atctgttgta tattctgtag
    19741 gaatcgtttg attagatggc acactcacag ctggcaagga taatgtaggc aatgtaaatg
    19801 ggctgacaga attttcgttt tcttttgatg attcttcttc tatttcgtct ggctttggta
    19861 ctgacacatc tgtatctttc ttattttctg tctcatcaat aatgtcatat tctttattat
    19921 cgacgatcag cttgtttgcc tggctgtggt aaagtgctgg atcgattgga aaactcagat
    19981 cgatagtttg tttagtgttt gatgagattt ccaacgtaat tttcccgcta tttacctgat
    20041 aagcatagcc atctccttct tttctttcca catcacttaa gtaattttcg actagaccaa
    20101 tttctttttc tatcttttca gcactggtgt tattcgcatt tagcttgatg ttcagtgctt
    20161 tttttccaga ctgatccgaa atgacttcag ctgaaattgt ttctaaaact gttggatcat
    20221 ctgtagtgtc tgctattgca gataatggca caaagtttga taaactcaat attatcagca
    20281 tgaaaataac tttcagtttc ttccctgtgg tcgtcatttt tcccctcctt tttctttttt
    20341 tctgttttga cgtgaatagt gaaaattatt aaaataaaca ggcgttacat aattttattt
    20401 attttaatat gataattatt atacgaaggg cgctaaaggg aatcacacca attttcatac
    20461 caattggttt catttatgaa gttgattcct tcgattaatg agcgtttcat tgaaagaaaa
    20521 gggttgaggg agaaaaacat atgatcaggt tgttggaagg aaactataga aagatggaaa
    20581 aaatcattcg aattctgtcc atttctgaca agtggatgac taaaaaagaa cttgccaaac
    20641 gaattggtag ttcagaatct acatttgtaa ggtatatcga agagatcaaa atccgctggg
    20701 gaacggatgt aacgattcaa tcttcacaaa aattggggta tcgtcttgaa catttgaatg
    20761 taccagctta tttaaatgtt ctgatggaaa tgtcgcaaag ttctacaaac agtcgtttat
    20821 taaatgagat tattgtcaat ccgggtaaaa cgattgagta ttattgtgaa aaaatttcca
    20881 tcagccggtc ttcttttaca cgtaagttga aacaatgcaa tcaaatttta gaaagctatt
    20941 tattaaaagt gatcgttgac caaggttttc agttaactag ccttaaaagt gagctccagt
    21001 tgcgtatctt tgttaccttt ttctttttaa gttactacgg aagacgcacg ttgccatttc
    21061 caatcgaaaa aaagaagatc aaagaaatta tggtcaagaa taattgtcag atgaatttgt
    21121 ttcaggaaga aagcccatat gagcaatctt tctttattat gtattttgtt gtgcatctca
    21181 tgagagaatc ccaaggaact ccatttgaat ggaaagctgg agactcttat gtacagttga
    21241 taaatatcga taaaaaagac ttcttaatct tgaaaaatct cttaggaaaa ttgaagtaca
    21301 gcagctatat aaaagtagtg aactattttg tcaatacgat tttttcagaa ttttcggaga
    21361 aagaaaaaaa tgaaatcagt gagcagatac gaaaaaatat gtcctactgt tcgttttcat
    21421 ccgctgattg caaagaaaaa aacgaagaat atgttgttca attattaacg caaatttatt
    21481 ttttctcccg tattttccca tacgatacga ctcatttgac gatccgtgca acttactttg
    21541 cacagcagat gcaacaccgc cagatacgtc tatatgctgg atttcgtgca gaacttcaat
    21601 tttattccac tctactgaat cagaatctga tttattattt atctagctat atcttttgga
    21661 tgcttatcgg taatcctgaa attcaccatt atacttctga taaaaaaata ctgattatca
    21721 gcgacttaag tcttcgacat agtcaatata ttgaagaata tatcagtgat attcttgctg
    21781 tgcataaaat tcactctgag acaactgcta ttactgaaga tcagctgtcg aaatacaatc
    21841 ttctcgagta tgatctgatc gttacgaatc aacccatttt gaatgcccat gttcctcata
    21901 tattgattga tgatagtgtg tcattcgcaa atgaagaaga actcatccgc ttattcgagt
    21961 tatgaataat caaaaaacag ctatgtataa accaccctga taaaaatttc aggacaaata
    22021 cacatagctg tttcttttta ttgtattcct tcagcaatcc aacgagattt atagcgaaag
    22081 tcttttaaca actcttcttt tgtccaatta tttgcaatga gatccgtcaa agtgttcatt
    22141 acgagggtca tggaaaagta taggaaacta actgcttctt ccgacgattg aatggagaaa
    22201 tgattgattc ttaataattc cagccatttt tcgttcattg gagaatcagc cgatagttct
    22261 ctacgtttgg ttgtctgctg atcatttcgc tgggttaaca agtataacct ttgccaatag
    22321 atactttcgt gatctaagtc gcagcaccac tctaaatatt tttcgatccc caaaaagaaa
    22381 tgttgtttgt tttcgctaat gaattttaag atatcttgat ggactatgtg agaactgctt
    22441 ttgatcgtat acaaataagc atcttccaaa tcttgaaaat atttataaaa agcaccgcgc
    22501 gacatcccca tcttgtcaac gatttctgag actttgactt ggctgatgtg ctgtgagcaa
    22561 aatatctcca gtaataggtc atcgattctc tgtttctttg cgttcgataa attgaaaaaa
    22621 gtttcttttg gcatccacat ctctccttta tctctgatta tacgtggata gcccttcatt
    22681 gtcatgaagg attcattcct tctttttctc ttcttctgtc aagtacccat cttccattcg
    22741 ataaacgcga tcactccatt gaatcatacg gacatcatga gtaaccataa tagtcgcttt
    22801 ttgtttctca tgagcttctt taactagtaa tttgacgact tcatatgcat gatctgtatc
    22861 caaactagct gttggttcgt ctgctaagat caagcttggc tcattatata aagcgcgagc
    22921 aattgccact ctctgtcttt ctccaccaga aaggtcttta ggataactat ttttaagtga
    22981 ctggatatct aaagattgca gcaaggaatc gatttttgtt gaatcttctt tttttgaagt
    23041 aacttggtca actagttcaa attgttcctt taccgttaaa aaaggaatca aattagagct
    23101 ttggagaata aatcctattt ctttaaagcg taaatctgct cgtttttttt ctggaagctc
    23161 agttagtgag tgaccgttga tcactatttc tccggaagtc ggtgtttgca atcctcctga
    23221 aatggtaagg aaagtacttt tacctgaacc agaaggacca atgatgctga cgaattctcc
    23281 ttcctttaca taaaaatcaa ttgctttcaa agctgagacc tttgtatgac cagaaccaaa
    23341 tgttttggta acttttttca tcgttaatat ttttttcatt tttattaacc tcctattgct
    23401 gtaattgggt ctactttggt tatcgtacgt atcgaaaaca atccgcctag cattgcgaca
    23461 atgatcaaaa tcccactata tagcaaccat tgtgaccaaa aaacagcaaa aggcatcgcg
    23521 cttggtaaaa tcagactagt caaataagca aacaaaagag caagcagaac gcctaccacc
    23581 ccaacaataa aggactgtgc tactaaagat ttagcgatga agaaattttt gatcccttgt
    23641 gctttcatta ctccaaaaat agcagtcttc tgaagtgtca tcacgtacat gaaaataccg
    23701 accacggcag caaccactaa gaacaaaaag tatatcatcg catttaaggt catattttgg
    23761 gcagaatagc caggaatact ttcaatgaat gtcccaatag ttaataactg tagacccttc
    23821 gatgcttttt ctttcgaaat tttagctgaa tcctttatta cgatcccatt gatcggctgt
    23881 tcttcttcag aagcaaacgg ctgttgtcca tacttcaaag cagtccacgt atctagggac
    23941 gcatagatga cgggagaaac tgtgtaataa gtttcaggaa agataccgac aatcgtcaaa
    24001 ggatcgtcgt aactgccaat tttgatcgta tctccaattt tatagcctga atcagccaga
    24061 ttttgagaga tgatgatttc attctttgtt ttaaattcat gccctttcgt gagttttggt
    24121 aataaaaatg cttctttcgt tgtgccgaaa actgtaacat tttctttgtt ttttcctttg
    24181 attgctccgc tgtacaatcc gattggtgct ttctctcctc cttcaatgta tttcagatct
    24241 cctcttgtta attgtgaagc tgcaaatact tgatttgcat cctccgacaa aacaatctct
    24301 tgtgcgtccc aatcatcgat tgctttttta aactcttctg aaagtccatt cgctagtcct
    24361 gacaacatga atacgacata cgcaatcaag aacataatac cgacgatcaa gccatatcgt
    24421 aatttagaat agcgaatttc tttgatagct agaaacattt gtttttcctc cctatgatag
    24481 attgatagtg acaaaatgtc acttgttgaa tagtgtaact ctaaagtgac aatttgtcac
    24541 ttgtgttgtt tttttcttat caataaattg tctaagacat ctttcgataa aaccttaaca
    24601 tgagtcataa aaaatttatt taagccttat ttatgctttc catgataaac taaagtgacc
    24661 aaatcaatga ggtgggaaaa tgattaaact attagtagta gaagacgata aagtattatc
    24721 caataatata aaagaaatac tcgctgcaat cggcgagata acacaagttt atgatggtag
    24781 tgaaggactg ttcgagttgg aaagtggagt ttatgatctt gcaatcttgg atttgatgat
    24841 gccggaaatg aatggatatg aagtgttagc aaaaatacgg aaagaaaaaa tacagactcc
    24901 agtattgatt ttgactgcaa aagatagttt ggaagataag attgaaggat ttgaacgagg
    24961 tgcagatgat tatctaacaa aacctttcta tcgagaagaa ctgatcatgc gcgtgaaagc
    25021 attattgaaa cgctcgctag gtctctttga tgaaaatgtt ctgaagtata aggatatcag
    25081 ttgtgattta aaaagcaatg aagtcttgta taaagaacaa gttttgccca tacaaggaaa
    25141 agagtttgaa ttgctcgttt attttttaca aaataaggga atcattttga caaaagagca
    25201 gatatttgac cggatctggg gatttgattc tgatacgacg attacagtta ttgaagttta
    25261 tatgagcaac ttacgaaaac atctgcgaag tactggattg gataaagaaa tcaaaacctt
    25321 acgtaatgtc ggttatatac tgcaaagggt gtgatgcaat gaatggagat attacacgaa
    25381 agcaacgtag tcgctttttt gcgacaaatg tagcagcatt tgcttttatc ttttttcttt
    25441 tgggattcat tactttacag atattaaacc aatctgcata cagagaaaca gatctgtcat
    25501 tagagaaaat aaattttgat tctcgaacag tacaattaga gatacaaaga tatcagcaag
    25561 gcgatccctt tttaaacccg actcaaacgg aacaaaacag aacaaacatg gaacagccat
    25621 taatggaacc atcaaatgac cgttttaaca ctcaagtgat cttgtggtct aaaaatggtg
    25681 agatattgaa taaagcagct attggtgggc gtttcaacca aatcaaagaa ttaaaaatgg
    25741 atacgaaaaa tctgaatacc atccaaaata ttgaattaaa tgaagacagt ggctcatctg
    25801 ccctctcttt ccgttcgatt acgaaaaaag cggagacgaa tcaagatggc gttgcctaca
    25861 tccaaatttt agaaaataca aatcaaatca agaattcatt agcgactttt cgcacgatta
    25921 tgattttgtg tatgattgtt ttttggattc tctctattgg tatcagttat tacttgtcta
    25981 gtctaagcat gcgccctatt attctttctt ggagaagaca aaaagaattt gttgagaatg
    26041 cttctcatga attgcgcaca ccgttaacga ttattcaaaa tagtttggaa catcttttta
    26101 ccaagcctaa tcatactatt attgaagaat ccgaaagcat cgctcaagca ttgtcagaga
    26161 cgaggcgcct cactggattg acttcggatt tgctgacaat cgctcggaat gattctgatc
    26221 agcagctgct ttcaaagcaa atgatcaata cacaagaata tatcgaacaa cttgttaaac
    26281 catttcaaga gatggccatc atagatggaa aagagtttat tctccataac gatgcaacat
    26341 tagaagtacc aattgatgaa aaaaaaatcc atcaagtttt ggttattttg ctggataatg
    26401 cattaaaata tacgaatcca gaagataaga tcattttgga ttcatctgtt aaccataaag
    26461 aatggctgat tcacgtaaag aatactggcc cttctatcag tgaagaagat caagcaagga
    26521 tttttgatcg attttatcgg gaagatcaat ctcgggcgaa agagactggc ggatacgggc
    26581 ttggcttggc aattgcaaaa caggtaatcg aacagcatca tggacagatt tctgtatcca
    26641 attatcttcc acaaggagtc gattttaaag tccaattgcc gttgaagcct aaaaaataat
    26701 gcttatccct aaaaaagggc tgtgacaaaa atcttgtcac agcccttttt tgttgcgaat
    26761 aaacggtgtt ccagaagtag cttcttcgga aataagccga aatttcttta agctgaccac
    26821 ttctgtcaca acctctttag cttacgctta cgatttttta ttgcggtctt caatgtgtac
    26881 atcaccgctt gtgtcaatat ccaattcttc tcggctaaca tcttctgtca ctttttcaac
    26941 atcttcatgt tcttctttat gaatcccaac ttcttcacga ataactgtat gtttgcttac
    27001 atctacttgc tcttctttga ttgggatagt aatcgtgtca tcttccaatt tttcgtctgt
    27061 tccctgtgaa gattgatctg ttactggttt gcgttcgatg acgatttctt cacgtttgac
    27121 cggtacttct accgtttcag tatcgttgac cacatgtttg tggatgtcga cttctccagt
    27181 tgtcacatca tgtgtattta catctaattt ttcttctttt agttgaattg tatcatcatc
    27241 tagatttggt ttgcgatcga tgtcttcagt cttgcttgta cccattgtat cagtctcgcc
    27301 aggtacgtcc atcggatcag ttcctggtgt catattcaat ggatccgttg tattttgaaa
    27361 gcctgtcgtg ccacctacgt ccattggatc tgttccagtg ccagtttcta atccagtccc
    27421 cattgtgctt gctgggctaa cagtatcttg tgtatccatt gtatcttctg ttgtttctgg
    27481 ctgacgatag ccttttactg tgatgacaaa ttttccatca gaaatatctc ctctatattg
    27541 atataaagga tcattttctg gtgtagccgt ctcagaatca taggtatcaa aagaaaaagt
    27601 atcttttatt ttttcccata aagaacggtc ttcttcacca tccatccgat tttcatctgt
    27661 ttcaacatct ataccagaca atccgtcaaa tcctagtcta gatgctgctt catcagtagt
    27721 ataaataacg atatcatctc gttcataccc ttcgttacgc aaccgttcaa ttactgataa
    27781 tgcttcttcc ctcgtactat agcttccgat gaccgttaaa tttttctctt ccatgtaaat
    27841 tcctcctagc aaatagattt atgattggta tattgttact tataaattta ttctatagga
    27901 gacgattgtt ttctacaaat atttagattg gaatttgatt aaaacaattt aattgaaatt
    27961 tgaaaac
//
LOCUS       DAFLWC010000031        27905 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.032, whole genome shotgun sequence.
ACCESSION   DAFLWC010000031 DAFLWC010000000
VERSION     DAFLWC010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27905
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.032"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(79..765)
                     /gene="gpmA"
                     /locus_tag="L1V17_001228"
     CDS             complement(79..765)
                     /gene="gpmA"
                     /locus_tag="L1V17_001228"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBN1236008.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(937..1518)
                     /locus_tag="L1V17_001229"
     CDS             complement(937..1518)
                     /locus_tag="L1V17_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1236009.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(1651..2334)
                     /gene="rpiA"
                     /locus_tag="L1V17_001230"
     CDS             complement(1651..2334)
                     /gene="rpiA"
                     /locus_tag="L1V17_001230"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HBN1236010.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            2653..3066
                     /gene="rpsL"
                     /locus_tag="L1V17_001231"
     CDS             2653..3066
                     /gene="rpsL"
                     /locus_tag="L1V17_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBN1236011.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            3150..3620
                     /gene="rpsG"
                     /locus_tag="L1V17_001232"
     CDS             3150..3620
                     /gene="rpsG"
                     /locus_tag="L1V17_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBN1236012.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            3714..5801
                     /gene="fusA"
                     /locus_tag="L1V17_001233"
     CDS             3714..5801
                     /gene="fusA"
                     /locus_tag="L1V17_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBN1236013.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            5973..7160
                     /gene="tuf"
                     /locus_tag="L1V17_001234"
     CDS             5973..7160
                     /gene="tuf"
                     /locus_tag="L1V17_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBN1236014.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            7567..7875
                     /gene="rpsJ"
                     /locus_tag="L1V17_001235"
     CDS             7567..7875
                     /gene="rpsJ"
                     /locus_tag="L1V17_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBN1236015.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            7906..8535
                     /gene="rplC"
                     /locus_tag="L1V17_001236"
     CDS             7906..8535
                     /gene="rplC"
                     /locus_tag="L1V17_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBN1236016.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            8563..9186
                     /gene="rplD"
                     /locus_tag="L1V17_001237"
     CDS             8563..9186
                     /gene="rplD"
                     /locus_tag="L1V17_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBN1236017.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            9186..9476
                     /gene="rplW"
                     /locus_tag="L1V17_001238"
     CDS             9186..9476
                     /gene="rplW"
                     /locus_tag="L1V17_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBN1236018.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            9515..10348
                     /gene="rplB"
                     /locus_tag="L1V17_001239"
     CDS             9515..10348
                     /gene="rplB"
                     /locus_tag="L1V17_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBN1236019.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            10391..10669
                     /gene="rpsS"
                     /locus_tag="L1V17_001240"
     CDS             10391..10669
                     /gene="rpsS"
                     /locus_tag="L1V17_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBN1236020.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            10692..11039
                     /gene="rplV"
                     /locus_tag="L1V17_001241"
     CDS             10692..11039
                     /gene="rplV"
                     /locus_tag="L1V17_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBN1236021.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            11053..11709
                     /gene="rpsC"
                     /locus_tag="L1V17_001242"
     CDS             11053..11709
                     /gene="rpsC"
                     /locus_tag="L1V17_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBN1236022.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            11712..12146
                     /gene="rplP"
                     /locus_tag="L1V17_001243"
     CDS             11712..12146
                     /gene="rplP"
                     /locus_tag="L1V17_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBN1236023.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            12136..12324
                     /gene="rpmC"
                     /locus_tag="L1V17_001244"
     CDS             12136..12324
                     /gene="rpmC"
                     /locus_tag="L1V17_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBN1236024.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            12349..12615
                     /gene="rpsQ"
                     /locus_tag="L1V17_001245"
     CDS             12349..12615
                     /gene="rpsQ"
                     /locus_tag="L1V17_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBN1236025.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            12673..13041
                     /gene="rplN"
                     /locus_tag="L1V17_001246"
     CDS             12673..13041
                     /gene="rplN"
                     /locus_tag="L1V17_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBN1236026.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            13078..13386
                     /gene="rplX"
                     /locus_tag="L1V17_001247"
     CDS             13078..13386
                     /gene="rplX"
                     /locus_tag="L1V17_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBN1236027.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            13414..13953
                     /gene="rplE"
                     /locus_tag="L1V17_001248"
     CDS             13414..13953
                     /gene="rplE"
                     /locus_tag="L1V17_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBN1236028.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            13972..14157
                     /locus_tag="L1V17_001249"
     CDS             13972..14157
                     /locus_tag="L1V17_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBN1236029.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            14193..14591
                     /gene="rpsH"
                     /locus_tag="L1V17_001250"
     CDS             14193..14591
                     /gene="rpsH"
                     /locus_tag="L1V17_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBN1236030.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            14623..15159
                     /gene="rplF"
                     /locus_tag="L1V17_001251"
     CDS             14623..15159
                     /gene="rplF"
                     /locus_tag="L1V17_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBN1236031.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            15320..15676
                     /gene="rplR"
                     /locus_tag="L1V17_001252"
     CDS             15320..15676
                     /gene="rplR"
                     /locus_tag="L1V17_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBN1236032.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            15697..16197
                     /gene="rpsE"
                     /locus_tag="L1V17_001253"
     CDS             15697..16197
                     /gene="rpsE"
                     /locus_tag="L1V17_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBN1236033.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            16212..16391
                     /gene="rpmD"
                     /locus_tag="L1V17_001254"
     CDS             16212..16391
                     /gene="rpmD"
                     /locus_tag="L1V17_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBN1236034.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            16435..16875
                     /gene="rplO"
                     /locus_tag="L1V17_001255"
     CDS             16435..16875
                     /gene="rplO"
                     /locus_tag="L1V17_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBN1236035.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            16875..18170
                     /gene="secY"
                     /locus_tag="L1V17_001256"
     CDS             16875..18170
                     /gene="secY"
                     /locus_tag="L1V17_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBN1236036.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            18232..18879
                     /locus_tag="L1V17_001257"
     CDS             18232..18879
                     /locus_tag="L1V17_001257"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBN1236037.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            19070..19288
                     /gene="infA"
                     /locus_tag="L1V17_001258"
     CDS             19070..19288
                     /gene="infA"
                     /locus_tag="L1V17_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBN1236038.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            19321..19437
                     /gene="rpmJ"
                     /locus_tag="L1V17_001259"
     CDS             19321..19437
                     /gene="rpmJ"
                     /locus_tag="L1V17_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBN1236039.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            19455..19820
                     /gene="rpsM"
                     /locus_tag="L1V17_001260"
     CDS             19455..19820
                     /gene="rpsM"
                     /locus_tag="L1V17_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBN1236040.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            19848..20237
                     /gene="rpsK"
                     /locus_tag="L1V17_001261"
     CDS             19848..20237
                     /gene="rpsK"
                     /locus_tag="L1V17_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBN1236041.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            20317..21255
                     /locus_tag="L1V17_001262"
     CDS             20317..21255
                     /locus_tag="L1V17_001262"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBN1236042.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            21283..21663
                     /gene="rplQ"
                     /locus_tag="L1V17_001263"
     CDS             21283..21663
                     /gene="rplQ"
                     /locus_tag="L1V17_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBN1236043.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            21935..22774
                     /locus_tag="L1V17_001264"
     CDS             21935..22774
                     /locus_tag="L1V17_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBN1236044.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            22750..23619
                     /locus_tag="L1V17_001265"
     CDS             22750..23619
                     /locus_tag="L1V17_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBN1236045.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            23609..24406
                     /locus_tag="L1V17_001266"
     CDS             23609..24406
                     /locus_tag="L1V17_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBN1236046.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            24609..25355
                     /gene="truA"
                     /locus_tag="L1V17_001267"
     CDS             24609..25355
                     /gene="truA"
                     /locus_tag="L1V17_001267"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBN1236047.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKVRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            26020..26257
                     /locus_tag="L1V17_001268"
                     /pseudo
     CDS             26020..26257
                     /locus_tag="L1V17_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299509.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(26401..27177)
                     /locus_tag="L1V17_001269"
     CDS             complement(26401..27177)
                     /locus_tag="L1V17_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBN1236048.1"
                     /translation="MNIHHIRNATAILDYGGKKFLIDPMLAEKGTLPPFISKGPFPSP
                     RKDQMNPLVDLPMPVEDIINGIDAVIVTHLHLDHWDDIAKEVLPKEIKLFVQDENDAN
                     EIRLYGFKNVEVLREDTVFESIQLVKTKGKHGRGEILNYVGNVCGIVFKHSTEKTLYF
                     TGDTVWYEAVKQTIDQYNPEIIVANAGDNHFLVGESLIMGKDDLYELHKAIPDSTIIA
                     VHMEAVNHWGLSREELKSFNKEKGISEKVLVPEDGDNIFI"
     gene            27300..27707
                     /locus_tag="L1V17_001270"
     CDS             27300..27707
                     /locus_tag="L1V17_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HBN1236049.1"
                     /translation="MLDQTDINIIEELSKNSRITMKELGEKVHLTGPAVSARVTKLEE
                     SGVIENYTVKLNMEKLGFSIHAFLIIITQNLNHKPYLSFIKNHEKFLIRNYKISGGGC
                     YLLECRFTSKKSMNSFLEQLNEYANYKLSIVID"
BASE COUNT         9096 a         5093 c         5871 g         7845 t
ORIGIN      
        1 agttggcagg agaaaaccgt ttatacgaaa aaagggactg tgacaaatcg tgtcacagtc
       61 ccttttttat agtgtttttt ataggtagta ttttttagca actgttaagt catcatttaa
      121 ttcataaaca agtggttgac ctgttggaat ttcaagatcc atgatgtctt cgtcagagat
      181 accttcgata tgtttagcta gggcgcgtaa tgagttacca tgtgcagcta ctaaaacagt
      241 tttgttgtct agtaatgctg gagcaatttc atcttgccag aatggcaaag cgcgttctaa
      301 tgtcactttc aagttttctc caccaggaat atcgcgtttg tctaacattg cgtaacgacg
      361 gtcatttgct gcagaacctt cgtcagtttc ttccattaat ggaggaagag tatcgtaaga
      421 acgacgccag atgtgcactt gttcgtcgcc gtatttttca gctgtttctt ttttgttcaa
      481 accttgtaat ttaccatagt gacgttcgtt taagcgccat gatttgattt gtggtaccca
      541 aagttgatct gaatattcta agatcaagtt acatgttttg attgcacgag ttaaaacaga
      601 agtgtaagca acatcaaatt cgattccagc ttctttgatt ttgcgtccgc cttcttttgc
      661 ttcttcgatt ccttctggtg ctagatttac atcagcccaa ccagtaaatt ggttcaatgc
      721 attccattca ctaagaccgt gacgagaaaa aactaatttt ggcatgttta gctctccttt
      781 taagataggt ttatatttct gaaattttca gttctgtttt attgtacaat tttttggaag
      841 agatttccat cgaaaaatta gataagattc tatgagaaaa caagtagaga atataaaaaa
      901 acgaacagtg cccacgcaac tgttcgtttt taggtattag atgcataatt gctcgatttc
      961 tttttcaggt aaattgatat atttataaca tgttccaact gaaacaccgc attttgaaga
     1021 aataaattgg atcgtttctt ttttttcata atagagacgt cggatttttt tgatcgtttt
     1081 tgcatcgatt tttggtcttc cgccgatttt tcctttttta cgagcttcat ctaatccaac
     1141 taatgtacgt tctttgatca atgcgcactc catgtttgct aggttttcca ttaattggaa
     1201 atagattttt cccatttcgc gcgtatcgat tccttcatca agactaatca agtgcagccc
     1261 gcgatctttg aataattgcg tgagttctgt taattgccgc gtagatttgc ctaatcgatg
     1321 aagttggcaa atgactagtg catcgccttg ttgcatgtca gcgatcactg actccaaatg
     1381 aacagcagta gaatcatttt gttccacttc atatgtctca tggaaaattt cttgacaacc
     1441 aaagtcagat aattgatcaa cctgagttgt taaatcaacg tcatttatgg ttgtgcgtgc
     1501 ataaccaata attttcatgg tgattccttt ctagcagtga ttttctaact ggatataaca
     1561 gtaaaaatgt agcataaagt acgtcaaaaa gatagttttt tcgcaaattt tccgctgtct
     1621 ttttttattg gatgatcaag cagtttttct ttatttacga cggattgcgt caagaatctc
     1681 aacgcctttt tctgagccga caactacttt agaaaccatg tttaggaaaa gcccatgttc
     1741 tactacccca acaagttcat ctaaataggt agctaagctt tctggctgtt cgatgacttc
     1801 tagatgcaga tcaatgatgt aatgaccacc atctgtggtt aagacttctc cgttttcgtc
     1861 tgtacgcaag acgggttgga atcttttttc ttcaaaaata tgaagtagct gttgggagcc
     1921 ataagggatc acttcaactg ggagtgggaa cttcccaagt ttatcgacta atttagaaga
     1981 atcaacgatc caaatcgttt cttttgagta cgtagcgact attttctcga aaagcaaagc
     2041 agcgccgccg cctttgatcc cttgaaaatc agcactgatt tcatcagcac cgtctattgt
     2101 caaatcgact acggggactt catcaatact ctttaacggt attcctaatt tttccgcttg
     2161 ttcttttgtc gcatttgaag tagtaactcc tgtgatacgt aaaccttctt cacgcatacg
     2221 gcgaccaatc tcttctacca tataataggc ggttgaaccg gtcccgagac ctacgatcat
     2281 cccgtccttt acgaatttcg cggcttcaat gccagctaat tgttttaaat tcatctttgc
     2341 gtccaccttt ttttagtttg agcatcgtgc tttcctcact attttagcgt gatttacggt
     2401 aaaaagatac cattcttttt tattccaata aagctttttc aaaaaaaatt gcatctcttg
     2461 ttgacatgtt ttttcattcg tgatattcta acaaaggtgc tttatctaca ggtttctgtg
     2521 aagaaacgtg ctgactgttt atcaaagcat atttgataag gatgcagaca ttgcatttat
     2581 tttttatcac aaaaaaagaa ccacctggat gtgtggaact agacgcaaat cgtgggaagg
     2641 aggaaacaag gaatgcctac aattaaccaa ttagtacgta aacctcgtaa atcaaaggtg
     2701 gaaaaatcta attcacctgc tttgaacaaa ggatataaca gctttaagaa aactcaaact
     2761 aacgtaaact cacctcaaaa acgtggggta gcaactcgtg tgggtacaat gacacctaaa
     2821 aaaccgaact cagctttacg taaatatgca cgtgttcgtt tgtcaaactt aattgaagtt
     2881 actgcttata tcccagggat tggtcataac ttacaagaac acagtgttgt attattacgc
     2941 ggtggtcgtg taaaagactt accaggggta cgttaccata tcgttcgcgg tgctttagat
     3001 actgctggtg ttaacgaccg taaacaaagc cgttctaaat acggaactaa aaaacctaaa
     3061 gcttaatttt aattattaaa caaatgaaac ttgcttctac tatatagaag taattactat
     3121 gaacaatatt tcggaaggag gagttacgga tgccacgtaa aggtcctgtt gcaaaacgtg
     3181 atgttttacc agatcctatt tataactcaa aattagtaac tcgcttgatc aaccgtgtaa
     3241 tggttgacgg aaaacgcggg attgcagcta acattatcta taatgccttt gacttgatca
     3301 aagaatctac aggtaacgat ccattagaag tgtttgaaca agcaatgaaa aacgttcaac
     3361 ctgttcttga agttaaagca cgtcgtgttg ggggttcaaa ctaccaagta ccagttgaag
     3421 ttcgccctga acgccgcgtt actctaggtc ttcgttgggt agtaaactac gctcgcttgc
     3481 gcggtgaaca cacaatggaa gaacgcttag caaaagaaat catggatgct gcaaacaaca
     3541 caggtgcttc tgttaaaaaa cgtgaagaca ctcataaaat ggctgatgcc aaccgtgcgt
     3601 ttgctcacta tcgctggtaa gattctctct gtttggtcgg cttttataag tcgacctcag
     3661 atagtgtcct tatttttagc aactagatag taaagagagg agaaacaagg agaatgacca
     3721 gagaattttc tttacaaaac actcgtaata tcggtatcat ggcccacatc gatgctggta
     3781 aaacgactgc tactgaacgt atcttgtact atactggtaa aatccataaa attggtgaaa
     3841 ctcatgaagg agcttcacaa atggactgga tggaacaaga acaagaacgt ggtattacga
     3901 tcacttctgc tgctactaca gcacaatgga agggtcaccg aatcaacatc atcgacacac
     3961 caggacacgt agacttcaca gttgaagttg aacgttcatt gcgtgtactt gatggtgctg
     4021 taactgttct tgatgcacaa tcaggtgttg aacctcaaac tgaaacagtt tggcgtcaag
     4081 caacaactta tggtgtacct cgtatcgtat ttgcaaacaa aatggacaag atcggtgctg
     4141 acttcttata ttcagtatca actttacatg accgtttgca agcaaacgct cacccaatcc
     4201 aattaccaat tggtgcggaa gacgacttca caggaattat cgaccttgta acaatgaagg
     4261 ctgaaatgta tacaaacgat cttggaacag agatcgaaga aacagaaatt cctgaagaat
     4321 accgcgaatt agctgaagaa tggcgcgaaa aattggttga agctgtagct gaaactgatg
     4381 aagaacttac tttgaaatac ttagaaggtg aagaaatcac tgaagctgag ttaaaagaag
     4441 gtatccgccg cgcaacagtt aacgtagaat tctacccagt actatgtggt tcagcattta
     4501 agaacaaagg ggttcaatta ctattggacg ctgttcttga ttacttgcca tcaccgttag
     4561 atatcccagc tatcaaaggg attgacccta aaactgatga agaagtagaa cgtcctgcag
     4621 acgacagcgc tcctttctca gctttagcat ttaaagttat gactgaccca ttcgtaggtc
     4681 gtttaacttt cttccgtgtg tactctggtg ttttacaatc aggttcatac gtacaaaacg
     4741 caacaaaagg caaacgtgaa cgtgttggtc gtatcctaca gatgcatgcc aactctcgtt
     4801 cagaaatctc tgaagtttac gctggagata tcgctgctgc tgttggtttg aaagacacaa
     4861 ctactgggga cacactatgt gatgaaaaga gtctagttat tcttgaatcc atggaattcc
     4921 cagaaccagt tatccaagtc gctattgaac ctaaatcaaa agctgaccaa gataaaatgg
     4981 gtgtggcttt acaaaaacta tctgaagaag atcctacttt ccgtgctgaa acaaacgtgg
     5041 aaacaggcga aacaatcatc gctggtatgg gtgaacttca cttagatatc atcgttgacc
     5101 gtatgcgtcg tgaattcaaa gttgaagcta acgtaggtgc gcctcaagta tcttaccgtg
     5161 aaactttccg tgctggcact caagccgaag gtaagtttgt acgtcagtct ggtggtaaag
     5221 gtcaatacgg tcacgtatgg attgaattta caccaaatga agaaggtgct ggtttcgaat
     5281 ttgaaaatgc gatcgtcggt ggggttgttc ctcgtgaata cattccagct gttgaaactg
     5341 gtttgaaaga tgctatggaa aatggtgtct tagctggcta tccattagta gatatcaaag
     5401 ctaaacttta cgatggttca taccatgatg tcgattcaaa tgaaactgcc ttccgtgttg
     5461 ctgcttctat ggcattacgt gcagcagcta agaaagctaa tccagtaatc cttgaaccaa
     5521 tcatggctgt agaagttgtt atccctgaag attatttagg tgatgttatg ggtcacgtaa
     5581 ctgctcgtcg tggacgtgtt gaaggtatgg aagctcgcgc tggcggccaa caagttgttc
     5641 gtgcgatggt tccacttgct gaaatgtttg gttatgctac aactcttcgt tctgctactc
     5701 aaggtcgtgg tacatttaca atgacatttg accactacga agatgtacca aaatcagtac
     5761 aagaagaaat cattaagaaa aacggcggaa aagctgaata atttcttgaa accggatagt
     5821 cctgcaaaga gattatccaa agagactata tttttaatat agtttcgtgt aaaataatta
     5881 tcgatgatat gggcatgtgg tgtaccttgt gtacatcata tacctatcag acaaataaaa
     5941 aatatattgt atttttagga ggacatttta aaatggcaaa agaaaaattt gaccgttcta
     6001 aaccacacgt taacattggt actatcggac acgttgacca tggtaaaact acattaacag
     6061 ctgcaatcac aactgtacta tctaagaaaa acggcggcca agctatggct tacgatcaaa
     6121 tcgatggtgc tccagaagaa cgcgaacgcg gaatcacaat ctcaacagct cacgttgagt
     6181 atgaaacaga tacacgccac tacgctcacg ttgactgccc aggacacgcg gattacgtta
     6241 aaaacatgat cactggtgct gctcaaatgg acggagctat cttggtagtt tctgctgctg
     6301 acggcccaat gcctcaaact cgtgaacaca tcctattgtc tcgtcaagtt ggtgttcctt
     6361 acatcgttgt attcttgaac aaagtagaca tggttgatga cgaagaatta ctagaattag
     6421 ttgaaatgga agttcgtgac ctattaacag aatacgaatt ccctggtgac gatgttcctg
     6481 tagttgctgg atcagctttg aaagctctag aaggcgacgc ttcatacgaa gaaaaaattc
     6541 ttgaattaat ggctgcagtt gacgaataca tcccaactcc agaacgtgac aacgacaaac
     6601 cattcatgat gccagttgaa gacgtgttct caattactgg acgtggtact gttgctacag
     6661 gtcgtgttga acgtggacaa gttcgcgttg gtgacgaagt tgaagttgtt ggtattgctg
     6721 aagaaacttc aaaaacaaca gttactggtg ttgaaatgtt ccgtaaattg ttagactacg
     6781 ctgaagctgg agacaacatt ggtgctttac tacgtggtgt tgcacgtgaa gacatccaac
     6841 gtggacaagt tttagctaaa ccaggtacaa tcacacctca tacaaaattc tctgcagaag
     6901 tatacgtgtt gacaaaagaa gaaggtggac gtcatactcc attcttcact aactaccgtc
     6961 cacaattcta cttccgtaca actgacgtaa caggtgttgt tgaattacca gaaggaactg
     7021 aaatggttat gcctggcgac aacgtaacaa tggaagttga attaatccac ccaatcgcta
     7081 tcgaaaacgg tactaaattc tcaatccgtg aaggcggacg tacagttggt gccggtgtcg
     7141 ttacagaaat caaagcttaa ttcacttaag ttttaaagta aagcaacatt tattcggacg
     7201 taatcgctcg gaacgaaggt cttaggatct ttgttccgag cttttttatt tattgcagga
     7261 tcaggaaaaa agacaggagt attataaata gaagaaacac gaaataaaag agtcagtatt
     7321 ttctaaatga aactttatga aaacaaaatg ttttttacaa gaaaaagcct tgctttgtga
     7381 gtttatatat attataatga caaaggtgcg tttactttag tgaattgcac agacgtaatc
     7441 agaatgattt cgtcggctaa gaaacgagag gttgcgacac gcccggacgc tttgccacga
     7501 acgagcgtga cggaaatttt cgtggagcta tgtctacttt tcaaaatagg cgaaggaggg
     7561 aacaagatgg caaaacaaaa aattcgtatc cgtttaaaag cgtatgaaca ccgtatttta
     7621 gatcaatcag cggataaaat cgtggaaact gcaaaaagaa ctggagctag cgtgtctggt
     7681 ccaattccat taccaactga acgcagtctt tacacaatca tccgtgcgac tcataaatac
     7741 aaagattcac gcgaacaatt cgaaatgcgt acacacaaac gtcttatcga cattgtgaac
     7801 ccaacaccaa aaactgttga tgctttgatg aagctagact taccatctgg tgtaaacatc
     7861 gaaatcaaat tataaaacta aaacaaaaat aatggaggtg tactcatgac caaaggaatc
     7921 ttagggaaaa aagtgggaat gacacaaatc ttcactgaat ctggtgaatt aattccagta
     7981 actgttgtag aagctactcc aaacgtagta ctacaagtga aaacaatgga aacggatggc
     8041 tacgaagcta ttcaagttgg ttaccaagat atgcgtgaag ttttatcaaa caaacctgcg
     8101 aaaggtcatg ttgcaaaagc aaacacggct cctaagcgct tcattcgtga attcaaaaat
     8161 gttgagctag gagaatatga agtaggaaaa gaaattacag tagatgtttt ccaagcagga
     8221 gacattattg atgtaacagg tactacgaaa ggtaaaggat tccaaggggt tatcaaacgc
     8281 cacggacaaa gccgcggacc aatggctcac ggttctcgtt accatcgtcg tcctgggtca
     8341 atgggtccag ttgcacctaa ccgtgtattt aaaaacaaac gtcttgctgg ccgtatgggt
     8401 ggcaaccgcg taactatcca aaacttggaa gttgtacgtg tcgatgcaga aagaaatgtt
     8461 atcttgatca aaggtaatgt tcctggagct aaaaaatctt taattactat caaatcagct
     8521 gtgaaagcta aataattgta ggaagaaagg aggaactaag gaatgccgaa tgtagcatta
     8581 ttcaaacaag atggaagcca aaacggtgaa atcacactta acgaagaaat cttcggaatt
     8641 gaacctaatg aaagtgttgt ttacgatgca atcgtaatgc aacgtgcgtc attaagacaa
     8701 ggaacacacg cggttaaaaa ccgtagcgct gttcgcggcg gcggacgtaa accatggcgt
     8761 caaaaaggaa caggtcgtgc acgtcaagga tctatccgct caccacaatg gcgtggaggt
     8821 ggcgtagtct ttggaccaac accacgttct tacagctaca aacttcctaa aaaagttcgt
     8881 cgtttagcaa tgaaatctgt attgtcagaa aaagttgctg aaaacaactt ggtagcaatc
     8941 gaaggcttga acttcgacgc accaaaaaca aaagaattca aacaagttct tgctaactta
     9001 tctatcgact ctaaagtatt ggttgttcta gaaaaaggta acgactttgc tgctttatca
     9061 gcacgtaact taccaaacgt ttctgtagta acttctgata atgtgagtgt gctagacgtt
     9121 gtatcaaata caaaagtgtt agcaacacaa actgctctta ctcaaattga ggaggtgctt
     9181 gcataatgaa cttactagac gtaatcaaac gcccagtgat cactgaaaaa tcaatgcttg
     9241 ccatggatga caagaaatac acttttgaag tggacactcg cgcaaacaaa actttagtaa
     9301 aacaagcggt agaagctgct tttgacgtta aagtcaaaaa cgtgaacatc gtgaacgtac
     9361 gtgcgaaatt caaacgtatg ggcaaatatg caggatatac aaaaaaacgt cgcaaagcga
     9421 tcgttacatt gactgaagat tcaaaagaaa tccaattatt cgaagctgct gaataagcac
     9481 taatagataa ctcattaaat taggagggaa aaacgtggcg attaaaaagt acaaacctac
     9541 ctcaaatggt cgtcgtaaca tgacaggttc tgattttgct gaaatcacaa catcaacacc
     9601 tgaaaaatca ttgttacaac cattgaaaaa ccatgctgga cgtaacaaca acggccgcat
     9661 cactgtacgt catcaaggtg gcggacacaa acgccaatat cgcgtgatcg acttcaaacg
     9721 taacaaagat aacgttgttg caactgttca aacgatcgaa tatgatccaa accgttcagc
     9781 taacatcgcg ttagtacact atgaagatgg agtgaaagct tacatcttag cacctaaagg
     9841 actagaagtg ggtatgaaac ttgtttcagg tccagaagca gatatcaaag tcggaaatgc
     9901 tcttccatta gaaaacattc cagttggtac tgttatccac aacattgaaa tgaaacctgg
     9961 taaaggtgga caattgatcc gttctgctgg tacaagtgct caagtacttg gtaaagaagg
    10021 caaatacgta ttgatccgct tgaactctgg tgaagttcgt atgatcttag ctgcatgccg
    10081 tgctacaatc ggttctgtag gtaacgaaca acacgaatta atcaacatcg gtaaagctgg
    10141 acgctctcgt tggatgcgta aacgcccaac tgtacgtggt agcgtaatga accctaatga
    10201 tcacccacac ggtggtggtg aaggtaaagc tcctatcgga cgtaaagcac cagtttctcc
    10261 ttggggtcaa ccagctcttg gttacaaaac tcgtaacaaa aaagctaaat cagacaaact
    10321 tattgttcgt cgtcgcaaaa ataaataatt actttgacca tgtgtcgcac attttgagag
    10381 gaggttcacc atgggtcgta gtttaaagaa aggacctttt gtcgatgagc atttaatgaa
    10441 aaaagttgaa gctcaagcag gggttgaaaa gaaaaaagtt atcaaaactt ggtcacgccg
    10501 ttcaacagtt ttcccaagtt ttgttggata taccatcgca gtttatgatg gacgtaaaca
    10561 tgtaccagtt tacatccaag aagacatggt aggacacaaa ttaggtgaat ttgcacctac
    10621 aagaacttat cgtggacatg ctgctgacga taagaaaacg aaacgctaat ttgaggggag
    10681 gataaatcca aatggcagaa caaatcacat cagctaaagc aactgcaaaa acagttcgca
    10741 cttcacctcg aaaagcccgt ttagtaattg accttatcag aggtaaaagt gtcgcagatg
    10801 caatttcaat cttgaaattc acaccaaaca aatctgctgg aatcattgaa aaagtattga
    10861 tgtcagcagt tgcgaatgca gaaaataact ttgacttaga tgttgaaaac ttggtagtaa
    10921 gcgaagcttt tgttaacgaa ggacctacaa tgaaacgttt ccgtcctcgt gcaaaaggat
    10981 cagcttctcc aatcaacaaa cgtacaagtc atatcacggt agtcgtatca gaaaaataag
    11041 gagggataat cagtgggtca aaaagtacat ccaattggaa tgcgtgtagg catcatccgc
    11101 gactgggatg ctaaatggta tgctgaaaaa gagtatgctg agttcttaca cgaagattta
    11161 agaatccgta aatttatttc aactaaactt gctgatgctg ctgtatcaac agttgaaatc
    11221 gaacgcgcaa caggtcgcgt aaacatttca attcacacag ctaaaccagg tatggttatt
    11281 ggtaaaggcg gttctgaagt cgaaagccta agaaaagaat taaacaaatt aactggtaaa
    11341 agaatccata tcaatatcgt ggaaatcaaa aaaccagatc tagatgcaaa attagtaggt
    11401 gaaggaatcg cacgtcaatt agaaaaccgt gttgctttcc gtcgcgctca aaaacaagcc
    11461 atccaacgct caatgcgtgc tggcgctcaa gggatcaaaa ctcaagtatc tggtcgtcta
    11521 aacggagcag atatcgctcg ttcagaagga tactcagaag gaactgttcc tcttcatact
    11581 ttacgtgcgg acattgatta cgcatgggaa gaagcagata caacatacgg aaaactagga
    11641 gttaaagtgt ggatctatcg tggagaaatt cttccaacta aaaaaaacac tgagaaagga
    11701 gggaaataat catgttagta cctaaacgtg taaaacaccg tcgtgaattc cgcggaaaaa
    11761 tgcgcgggga agctaaaggc ggaaaagaag tagcattcgg tgaatacggt ttgcaagctg
    11821 ttgattcaca ttggatcaca aaccgccaaa tcgaagctgc tcgtatcgca atgactcgtt
    11881 acatgaaacg tggtgggaaa gtatggatta aaattttccc tcacaaatct tatactgcca
    11941 aagcaattgg ggtacgtatg ggttctggta aaggggcacc tgaaggatgg gttgcaccag
    12001 taaaacgtgg taaaatcatg tttgaaatcg caggcgttcc tgaagaagta gctcgtgaag
    12061 cgttacgtct agcttctcac aaattaccaa tgaaaactaa gatcgtaaaa cgtgaggaaa
    12121 tgggtggtga atcgaatgaa ggttaaagaa atcagagaat taaccactgc cgaaatgctt
    12181 gatcaagaaa aacaattaaa agaagaattg tttaatctta gattccaatt agcaacaggt
    12241 caattagaaa acactgcacg tattaaagaa gtacgtaaat cgattgcacg catcaaaact
    12301 gtgttgcgtg aacaagctaa gtaattatgg aaggaggcca ttaagcgtat gactgaagga
    12361 agaaatcaac gcaaagttta tcaaggtcgc gtggtttcag acaaaatgga taaaacaatt
    12421 accgttgctg tcgaaacaaa gaaaaaccac cctatctatg gcaaacgcat gaactattct
    12481 aagaaataca aagtgcatga tgaaaacaac acagcaaaag ttggcgacat cgtgagaatt
    12541 atggaaactc gtccattatc agctacaaaa cgtttccgtt tgttggaagt agtcgaagaa
    12601 gcagttatta tctaataaca cgagattttc ctatatagat tgaatgcaaa atctgaaagg
    12661 aggatacaca acgtgatcca agcagaaagt cgtttaaaag tcgctgataa ctcaggcgca
    12721 cgtgaaattt tgacgatcaa agtccttggt ggatctggtc gtaaaactgc taacatcggt
    12781 gatgtgatcg ttgctacggt taaacaagca acgccaggtg gggttgtcaa aaaaggtgac
    12841 gtcgttaaag ccgttatcgt tcgaacaaaa tcaggagctc gtcgtacaga cggttcatat
    12901 attaaatttg atgaaaatgc tgcagtgatt attcgtgatg ataaaagccc tcgtggaaca
    12961 cgtatctttg ggccagttgc acgtgaacta cgtgaaaaca acttcatgaa gatcgtttca
    13021 ctagcaccag aagttttata atcttgagac acttatcaaa ggaggtgcga aacagttatg
    13081 tttgttaaaa aaggcgataa agttaaagtt atcactggaa aagacaaaaa caaagaaggc
    13141 gttgtactag cagcgttccc gaaaaaagat aaagttattg tcgaaggtgt aaatgtcgtt
    13201 aaaaaacacc aaaaaccttc tcaagctgct cctcaaggtg gaattgttga gatggaagcg
    13261 ccaattcatg tttctaacgt gatggtggtt gactctactg gtgtagctgg ccgagttggc
    13321 tacaaagaag tagacggcaa aaaagtccgt gtttctaaaa aaaccggtga agttttagat
    13381 aaataaaagt ttaaggaagg agggtcttac tgaatgaacc gcctaaaaga aaaatatctt
    13441 aaagaagtaa ctccatcatt gatggaaaaa tttaactata gctctgttat gcaaacacct
    13501 aaagttgaaa aaatcgtcat caacatgggt gttggtgatg cggtatcaaa cgctaaaaac
    13561 ttagataaag cagttgaaga attaactttg atcactggtc aaaaaccaat gattacaaaa
    13621 gctaaaaaat caatcgctgg attccgttta cgtgaaggaa tgccaattgg tgcaaaagtt
    13681 acattgcgcg gagaaagaat gtacgaattc ttagacaaat tggtttctgt ttcactacca
    13741 cgtgtacgtg acttccatgg tgtaagtaaa aaagcctttg acggtcgtgg aaactatact
    13801 ttaggtatta aagaacaatt gatcttccca gaagtagatt atgatttagt agataaagta
    13861 cgtggtatgg acatcgttat tgtaacaaca gcaaactctg atgaagaatc tcgtgagttg
    13921 ttgacacaat taggcatgcc attccaaaaa taattaaagg aggcgaacta cgtggctaaa
    13981 aaatcaatga ttgctaaaaa caaacgtcct gcaaaatttt caacacaagc ttatactcgt
    14041 tgcgaacgtt gcggacgtcc acattcagtt tatcgtaagt tccatctttg ccgtatttgc
    14101 ttccgcgaac ttgcctataa aggtcaaatt cccggcgtga agaaagctag ctggtaaaaa
    14161 gtaaattcgc ataagaagga ggtaaaagat caatggtcat gacagatcca attgcagatt
    14221 ttctaactcg tatccgtaac gcaaacatgg ttaaacatga gtctttagaa gtacctgcat
    14281 caaaaattaa acgtgacatc gctgaaatct tgaaacgtga aggtttcgtt cgtgatgttg
    14341 aatacatcga agatgacaaa caaggcgtga tccgtgtttt cctaaaattt ggtaaaaacg
    14401 gcgaacgtgt tatcacaaac ttaaaacgta tctctaaacc aggtttgcgt gcttatgtca
    14461 aagctgacga agtaccaaaa gtattgaacg gtttaggtat cgcaatcatt tcgacttctg
    14521 aaggtgttgt cactgataaa gaagctcgtg aaaaaaatat cggcggcgaa gttatcgctt
    14581 acgtatggta atcaagtaga atctacaagg aggtgtcttt aagtgagccg tatcggaaat
    14641 aaagtcgttg ttatccctga aggagtaaca gttactcaag acggaaacaa cgttacagtt
    14701 aaaggaccaa aaggtgaatt gactcgtact ttttcagcag atatcaaaat gaatatcgaa
    14761 ggaaacgaag taactttcac tcgtccaaac gacagtaaag aaatgaaaac aattcatgga
    14821 acaactcgtg cgaacttcaa caacatggtt gtaggtgtca gcgaaggttt ccaaaaagcg
    14881 ttagaactaa tcggggttgg gtaccgtgca caattacaag gatcaaaact tgtattgaac
    14941 gttggttact cacatccagt agaaatcaca ccaccagctg gagtaactgt tgaagtacca
    15001 gctaacacac aagtaattgt taaaggtgcg aacaaagaag aagttggcga attagctgca
    15061 aacattcgtg gaactcgtcc tccagaacct tataaaggta aaggtattcg ttatgttggc
    15121 gaatatgtac gccgtaaaga aggtaaaact ggtaaataat cgtttagaaa aattgcatag
    15181 aagccagcag caggaaaaag gcatttggct gaagtttacc ttcaaaaaaa tacattttta
    15241 cttgtgccgc agcttctatt tttcgaaacg tatttactgc ttgaaatagt agtacaataa
    15301 aaataaagag gtgacaattg tgattacaaa accagataag aacaaaacac gtcaaaagag
    15361 acatcgtcgt gtacgtaaca atatctctgg tactgctgag cgcccacgct tgaacgtttt
    15421 tcgttctaac aaaaacatct acgctcaaat tattgatgac gtagcgggtg taacgctagc
    15481 aagtgcctct accttggata aagaaatttc aggtggaaca aaaacagaag cagcacaagc
    15541 tgtcggtaaa ctagttgctg aacgtgcagc tgaaaaaggc attaaagtag tagtctttga
    15601 ccgtggtgga tacctttacc atggccgtgt gcaagcttta gctgaagctg ctcgcgaaaa
    15661 tggactagaa ttttagaaga aggaggaata ccattcatgg tttatatcga tccaaaacat
    15721 ttggaattag aagaccgcgt tgttgcaatt aaccgtgtaa caaaagttgt taaaggtgga
    15781 cgtcgtctac gttttgctgc tttagttgtt gtcggtgaca aaaacggaca cgtagggttt
    15841 ggtacaggta aagctcaaga agttcctgaa gcaatccgta aagcaattga agatgcgaag
    15901 aaaaacttag ttgaagtacc tatggttggt tcaacaatcc cacacgaagt aatcggtgct
    15961 tttagtggtg gtagaatcct aatgaaacct gctgtagaag gttctggggt tgctgctggt
    16021 ggaccagttc gtgccgtatt agaattagct ggggtagcag atatcacttc taaatcttta
    16081 ggctcaaata caccaatcaa cgttgttcgc gcaacagttg aaggtttgaa acaattgaaa
    16141 cgtgcagaag aagttgcaga acttcgcggc aaatcagttg aagaattaat cggataagga
    16201 ggacaacaat aatggctgaa ttaaaagtta ctttaaaacg cagtattatc ggacgtcctc
    16261 aaaaccaacg cgatacagtt aaagcgttag gtcttacaaa gattaacagt tcagtggtta
    16321 agccttctaa tgaagcaatt aaaggcatga tcaatactgt ttctcaccta gtggacgttg
    16381 aagaaattta atttagaaaa atcataacta gaacattaag gaggtgccaa acctatgaaa
    16441 cttcatgaat taaaacctgc tgaaggttca cgccaagtac gtaaccgtgt tggtcgtggt
    16501 acttcatctg gtaacggaaa aactgccgga cgcggacaaa aaggacaaaa agctcgttca
    16561 ggcggcggtg tgcgtttagg atttgaaggg ggacaaacac cattgttccg tcgtttacca
    16621 aaacgaggat tcacaaacgt gaaccgtaaa gactatgcag tcattaatct tgatgtattg
    16681 aaccgctttg aagacggagc tgaagtaact cctgttgctt tagttgaagc tggaatcgtg
    16741 aaaaacgaaa aagctggaat caaagtatta gctaatgggg aactaaacaa gaaattaact
    16801 gtgaaagcag caaaattctc taaagcagct caagaagcaa ttgaagcggc tggtggatca
    16861 atcgaggtga tctaatgttt agactattaa aagatgcttt taaagtaaaa gacattagat
    16921 cgaaaatcct atttactgta tttgtgttgt ttgtatttcg cctaggtgca catattactg
    16981 taccaggcgt aaatgctgct tcattgcaaa acctttcttc tttgccattt ttcaacatgt
    17041 tgaacttggt aagtggtagt gcgatgcaaa acttttccat tttctcaatg ggggtttcac
    17101 catacattac tgcttctatc gtcattcagc ttcttcaaat ggacatcgtg cctcgatttg
    17161 ttgaatggtc gaaacaaggg gaagttggtc gtaaaaaact gaatcaagcg actcgatatc
    17221 tgacattagt attggcattt atccaatctg tcggtatcac tgctggattc aatcaatacg
    17281 ctcaattagg tttcgtgaat aatcctaacg tagcaactta cgtaacgatc ggtttgattc
    17341 taacagccgg tacgatgttt gttacttggc taggagaaca gatcacagaa aaaggtatcg
    17401 gaaatggcgt atcaatgatc atttttgcag gtatcatttc tagattgcct gaaagtatca
    17461 gagaaattta tgaagattac tttataaata ttgatccttc agacatatgg aaatctgcta
    17521 tttttgtggc cattttacta gtagcggtct tgttgatcgt gacattcgta acatttttcc
    17581 aacaagctga acgcaagatc ccgatccaat atacgaaacg cgtagctggc gcgcctacaa
    17641 gcagctatct gccgttgaaa gtaaatgcag ctggagttat tccagttatc tttgctagtt
    17701 cgtttattgc tacgccaaat gctgttttac aagcattgag cggtagattc ggttctgaaa
    17761 actggtacaa agtgatgatg gagatcttta actataatac agcacctggt gctacgattt
    17821 atacgattct gatcgttgcc ttcactttct tctacgcctt tgttcaagta aaccctgaga
    17881 aattagcgga aaacttgcaa aagcaaggaa gttatatacc aagcgtacgc cctggtaagg
    17941 ggactgaaga gtatgtctca agattactga tgcgtttaag tacagttggt gcagtcttcc
    18001 ttggtttagt ggcattgctt ccaatcattg ctcaaatggt ttgggatctt ccacaatcaa
    18061 tcggattagg cggtacaagc ttactgatcg ttatcggtgt agctttagaa actgcgaaac
    18121 agttagaagg cttaatgctg aaacgtaaat atgttggatt cattgagtaa gaaagcgtgt
    18181 tgaggtttcc cctcaacaca cgttctcaca catttattag gagggaaaac aatgaacctc
    18241 attttaatgg ggctgccagg cgcaggtaaa ggaacacaag ctgaaaaaat cattgatgct
    18301 tatggtattc cgcacatctc aacaggagat atgttccgcg cagcgatgca aaacgaaaca
    18361 gctcttggcc tggaagcaaa gtcttatatg gataaaggtg cattagttcc tgatgaagta
    18421 acaaatggaa tcgtgaaaga gcgactagct gaaccagata cagagaaagg cttcttatta
    18481 gatggctttc cacgtacgct agatcaagca aaagctctgg acgcaatgct aaaagatttg
    18541 aataaaaaaa ttgatgctgt catcgatatc catgttggtg aagaaatctt ggtcgaacgt
    18601 ctagccggcc gatttatctg cagcaattgt ggagcaactt accataaaat tttcaaccct
    18661 acaaaagttg aagacacatg tgatcgttgc ggtgggcatg aattctatca aagagaagat
    18721 gataaacctg agacggttaa aaatcgtctg gctatcaaca tcaaaaatag tgaaccaatc
    18781 ttggcttatt ataaagaaca aggtttgcta aacactattg atggtgctcg tgaaatcgat
    18841 gctgtatttg cagatgtaca aaaaatcatt gaaaaatagc acgattgccc gtagccgact
    18901 tgcattatgc agttactctt gtcaagttca ataaattatg atagaatatg tcagtccgac
    18961 ttctagagaa tcctctagat gatccatttt gagaattttg aggtgggaac tgcagtttcc
    19021 gccattttat cgtgtgaaaa tgcgaaacaa gtacaaggag gtactgtgcg tggcaaaaga
    19081 agatatgatt gaagtcgaag gtacagtcgt cgaaactttg ccgaatgcaa tgtttaaagt
    19141 tgaactagaa aacggacacc aagttcttgc tactgtttca ggtaaaattc gtatgcatta
    19201 catccgtatc ttacctggtg acaaagtaac ggttgaattg tctccatacg atcttaaccg
    19261 tggccgtatt acttatcgct ttaaataatt gtactccgta aaactacagg aggtattatc
    19321 atgaaagtaa gaccatcagt aaaaccaatg tgcgaacatt gtaaagtaat tcgtcgtaaa
    19381 ggacgcgtta tggtgatttg cccagcaaat ccaaaacata aacaacgtca aggataattg
    19441 gaggtgctat aaatatggct cgtattgcag gagtagatat tcctcgtgat aaacgtgtag
    19501 tagtttcact tacttatatc tatggtattg gtaacactac tgctaaaaag atcttagctg
    19561 atgctggtgt atctgaagat gttcgcgttc gtgaattaac gaatgaacaa acagatgcta
    19621 tccgtgcaga agtagataaa ttaaaagttg aaggggatct tcgtcgtgaa gtgaacttga
    19681 acatcaaacg tttgatggaa atcggttctt accgtggaat ccgtcatcgc cgtggattgc
    19741 ctgttcgtgg acaaaacacg aaaaacaatg cacgtactcg taaaggccca gctcgcgcta
    19801 tcgctggcaa gaaaaaataa ttcttaagtg aaggaggtta aaacttcatg gcagcaaaaa
    19861 aagtgaatcg taaacgccgt gtgaagaaga atatagaagc aggtattgca catatccatt
    19921 ctacattcaa taacactatc atcatgatca ctgatactca cggaaatgca ttagcgtggt
    19981 catcagctgg ttcattaggt ttcaaaggaa gcaaaaaatc aactcctttt gccgctcaaa
    20041 tggcagcaga aactgctaca aaagcagcaa tggaacacgg attaaagact gttgaagtaa
    20101 cagttaaagg acctggttct ggacgtgaag cagcaattcg ttcattacaa gctacaggtt
    20161 tagaagtgac tgcaattcgt gacgtgactc cagttcctca taatggtgcc cgccctccaa
    20221 aacgccgtcg tgtttaatga gtgccgctca ttttgagttt tatcagtaac gtcattgaac
    20281 aagacacttt tcgttttgaa aggggtaaag ataagaatga ttgagttcga aaaaccaaga
    20341 atcgcaaaaa ttgatgaaga aaaagattat ggcaagttca tcgttgaacc tcttgaaaga
    20401 gggtatggga ctactttagg gaattcccta cgtcgtattt tattatcttc tttgccaggt
    20461 gctgccatca ctaatattca aatcgatggt gtactgcatg aattctctac catcaaaggt
    20521 gttagagaag acgtcactca aatcatcttg aacattaaag gcttagcgct gaaaatgtat
    20581 ggccaagaag aaaaaaccct tgaaatcgat attaccggac ctgctacagt aactgctggc
    20641 gatattatcg ttgatagtga tgtagaaatt cttaacaaag atatgtacat ctgtagtgtc
    20701 tctgaaggag ctacgttcca tgctcgctta acagtgaaac ctggacgtgg ttatgttcaa
    20761 gcagatgaaa ataaaaaaga agatatgcca attggcgttc ttccagtcga ttcaatctac
    20821 acacctgttc gtcgtgtgaa ctatcaagtt gagaacacac gtgttggaca ccgtgaagat
    20881 tttgataaat tgacgatgga gatttggaca gatggttcaa ttgaaccgtt ggaagcaatg
    20941 agtttgtctg cgaaaatcat gactgaacat ttggatattt ttgtgaactt aactgatgaa
    21001 gcaaaaaatg ctgaaatcat ggtcgaaaaa gaagaaacac aaaaagaaaa aatgttggaa
    21061 atgacgatcg aagagttaga cttgtctgtt cgctcttaca attgtttgaa acgtgcagga
    21121 atcaatactg tacaagaact tacaaataaa tctgagcctg aaatgatcaa agtccgtaac
    21181 ttaggacgta aatcattaga agaagttaaa gcaaaattgc acgacttagg tttaggttta
    21241 cgtaaagaag attaaaacct tttacgaagg agggaaacca acgtgagtta tcgtaaacta
    21301 ggacgcacat ctagccaacg taaagcgatg ttgcgtgatt taacaactga tttattaatc
    21361 aacgaacgta ttgtgactac tgaagctcgt gcgaaagaag ttcgctcaac tgcagaaaaa
    21421 atgatcactt taggtaaacg cggagatttg catgcacgtc gtcaagctgc ggctttcgta
    21481 cgtaatgaag ttgccagcgt gcgtgaagaa aatgaggaca tcgtcattga atcagcttta
    21541 caaaaactgt tcaacgatat tgcacctcgt tacgcagaac gtcaaggcgg atacacacgc
    21601 attttgaaga cagaaccaag acgcggtgat ggtgcaccaa tggttgtctt agaacttgtc
    21661 taaaatcaca ctaataacat cactttatag atgattcttt tagagtgtta tgatgttgga
    21721 agatattttt ccgagtctag ctcagcgctg ctcctcaagc gaatatcgct tggggagtaa
    21781 gcactcatca taaagtgttt ttttatacct tcaattacct gtcatgacag atatgtttga
    21841 aggcataaaa aaacatttta agcgagaaat aattgaaaat tttgtctttt tttgatagtg
    21901 ttagtaggaa ctttaggatg aagaaggagt aatcatggag ccaattattg aattagaaaa
    21961 gataaattat aaataccagc cagatgatct tcgccccgca ttgaaagatg tctcctttac
    22021 aattgataaa ggtgagtgga tcgctattat tggacacaat ggttcaggaa aatcgacact
    22081 tgccaaaacg atcaatggat tgcttctgcc agaatcaggg atcgtgaaag tgggaaatca
    22141 aatattggat gaagaaaata tttggacgat ccgacagatg gttggaatgg tttttcaaaa
    22201 tccagacaat cagtttgttg gttcgacagt agaagatgac gttgcttttg gtcttgaaaa
    22261 tcaagggatt cccagagaag aaatgctagt gcgtgtgaaa gatgcacttg agaaagttag
    22321 aatggctgag tttgcttcac gcgagcctgc tcgtttatca ggagggcaaa aacaacgtgt
    22381 tgccattgcc ggcgtggttg ccttacgacc tgatatcatt attttagatg aagcaaccag
    22441 tatgctagat ccagaaggtc gtgaagaagt gatctctacg atcaagaaga tcaaagaaga
    22501 aagtcaattg accgttatat ctatcactca tgatattgat gaagcagcta atgccaatcg
    22561 gatactagtg atgagacaag gcgaacttgt ccgtgaaggt acaccaaaag aaattttttc
    22621 tgctggtcct gaactgatcg acttaggtct agatctacca tttcctgaaa aactgaagag
    22681 cgcactgaaa gaacgtgggg ttgatgtgcc cagtgaatat atgacagaag aaaggatggt
    22741 ggattggtta tggacatccg ttttgaacaa gtagacttca cttatcagcc gaatacacca
    22801 tttgaacaaa gagccttatt tgacatcaat atgacgatca aagaaaacag ttatactgca
    22861 ttagtagggc ataccggaag cgggaaatca accttacttc agcatttgaa tgcgcttgtt
    22921 aagccaacaa gcggtacagt ccatattgga gaacgagata ttcagccgga tacggataat
    22981 aagaatttaa agcccatccg aaaaaaagtt ggcatcgtct ttcagtttcc agaagcacag
    23041 ctattcgaag aaacggtagc aaaagacatt gctttcggtc ctaaaaactt tggtgtcagc
    23101 gaagaagaag cactagtcct agcaaaagaa acattagaac aagttgggct ggatgaaagc
    23161 tatttggaac gttcgccatt tgaactttca ggagggcaaa tgcgtagagt agcaatcgct
    23221 ggtgtgcttg ccatgaggcc ggaagtactt gtattggatg aaccaacggc aggacttgat
    23281 ccccagggta gaaaagaaat gatggagatg ttttggcgtc ttcataagga acagcagatc
    23341 actattgtat tagttacgca tttaatggat gatgtagcca attttgcaga ttatgtctat
    23401 gtgttggaaa agggacgaat cgttaatagc ggggagccgc aagaggtctt tcaaaacatt
    23461 gaatggctaa aagaaaaaca actaggcgta cctactgcca ccgagtttgc agaagaatta
    23521 atggctaaag ggatgaactt tgctaccttg cctttgacag ctgaagaatt agcagacgct
    23581 atcgtccatt atgctggagg aaatgcccat gatgaataaa ttgatatttg gtcgttatat
    23641 gcctggagat tccttgatcc atcgattgga tccccgagct aaattattag ccagttttta
    23701 ttttatcgga atcatttttt tagcaaataa ttgggaaacg taccttttgt tggcattttt
    23761 cacattactt tctgtcttct tgtcaaaagt agatttgaaa ttttttatcc gaggcattcg
    23821 cccattgatc tggctaatcc tcttcactgt agctttgcag gtcttgttta caagtggcgg
    23881 agaaacttat tggagttggg gtgttttcca tatcactgaa tttggtgtga tgaacggcct
    23941 ctttattttc tgtcgattcg tgttgatcat ttttatgtcg actctactca cgcttactac
    24001 accgcctttg gaattatcgg atgcgattga gtacttgctt cgtccattga aagccgtacg
    24061 gttcccagtc cacgaaattt cattgatgct gtcgattgct cttcgttttg tgcctacatt
    24121 gatggacgaa acagaaaaga tcatgaacgc tcagcgcgct cgcggtgttg attttggtga
    24181 aggaaaccta gttcagaaaa tgaaagcagt cattcctttg ctgattcctt tatttgtcag
    24241 cagcttcaac cgtgcggaag atcttgcgac tgctatggaa gcaagaggct acaaaggtgg
    24301 ggaaggaaga acgaaatatc gtgtattgca ttggcataat agagacacga tggttatcat
    24361 tgcttttgta ttattaactg tgctactgat ctttttgaga ggataaacgt tcagtgggcc
    24421 gctatctatt cttttcttgc tgatctgttt gcaagaaagg atgcgagcag tgtatgacaa
    24481 gaaatattag ggtctgtggc agactaaggt cacaggcctc tttcttttat ctgaaaagaa
    24541 agaacgaaaa aattttataa aaaaatcatt attccagata accttttagg aacaaaggag
    24601 agaaaaacat ggtacgttac aaagcaatca ttgcatacga cggaacaaat tttaatggat
    24661 tccaaaaaca gccaaatggg cgtactgttc aagaagaagt agaaaaaaca ttacaaaaaa
    24721 tggcaaatgg aaaagaaatc acggtctttg gttcgggaag gacagatgcc ggagtacatg
    24781 cgattgggca agtaatccat tttgattatc cagaggagcg tccgttagaa cgaatgcgtt
    24841 tcgcgctaga tacccagtca ccagaggata ttgctgtaag acaagtagaa attgtttcag
    24901 aagacttcca cgcaagatat ttggtcaaag aaaagacgta tcaatttcga gtggatatag
    24961 ggaaaccacg cagtcctttt cgacgccatt atgcaagtta ttttccttac cctcttgatt
    25021 tggaaaaaat tcagcgggcg cttcctgatt tattagggac tcacgatttc acctcttttt
    25081 gtgcatcagg aagctcgata gaggataaag tacgtacgat ctacgaggct aagatggagg
    25141 taaatgaaac aaaagacgaa ttgttgttta catttagggg aaatggcttc ttgtataaga
    25201 tgatacggat cttagtagga acgcttttga aaattggcaa tggccgattg cctgaagata
    25261 gtatcccaga tattattgcg aaaaaagatc gtaatgcagc aggacctaca gcacatcctg
    25321 aaggacttta tttgtatgaa gtgaaatatg aataagaggt tgtgacagaa gtggtcagct
    25381 tcaagaaata agaaggaatt tacgaaaatt acttctcaaa attttgcaaa atttcggctt
    25441 attttcgaag gagctacttc tggaacaccg tgaatcagag gttgtgaaaa agctgccctg
    25501 catcaagtaa taagaacaac caaacaaaaa tagctcgtca tatttttcgt ttggttgggc
    25561 ttattaccgc agatgcaagc ttttgaacac cgtttaagga agaggttgtg aaatcagcgt
    25621 tttgacctga gtattagaga aacaaacgga aaaatagttc ctcatatttt gccgtttgtt
    25681 gagctaatac cgaaggtcag ctgattgaac accgtttaag aaagaggtcg tgagcctgtc
    25741 atttaactct gagtcacaag taacaatttc aaaaaacagc ttctcatctt tgatgaatat
    25801 cgtgacttgt ggacgaggcg ttgataagtg aatcatcttt ttgttaccta ttttttctgt
    25861 aaccaaaaaa cgatggaacg ttgttttgat tgcccttaat gaggacagtc ggaacaggtt
    25921 tgtcattttt atatttaaat ggcacaaatt tttctaatta tttgtcattt agcgctgaaa
    25981 atttttgcta tttatctaaa aaagtgataa ctacttaaga tgaagcagaa tatttacgcc
    26041 atacggcata caaccgcgaa aaatataaaa aaaagaaaac gattgaacgc gtttttgcag
    26101 tcgcaaagga aaagcatgga atgcgctaca tcaagtatcg agacttggaa aacaatcagg
    26161 tgtatacgct gattgttttt gctgcaatga atctgaaaaa gttgtccact tggcagttgg
    26221 aacatatgtc ttcatatctt ttattataca aaaatagcaa aagcaccagt ctacactctt
    26281 agtaaagagg aaactgatcc ttttgtctac attcttaaag tacttaaact aagtacttta
    26341 ttttactctt taggattgat acagtagcat ctatcccttt attaataatc ttttattttt
    26401 ttaaataaag atgttgtctc catcttcagg cactaaaact ttttcggaaa ttcctttttc
    26461 tttattgaaa gactttaatt cttctcttga cagtccccaa tggtttacag cttccatatg
    26521 aacggcaata attgtggaat ctggtattgc tttatgcaat tcatataaat cgtctttccc
    26581 cataataaga gattctccaa ctaaaaaatg attatctcca gcatttgcta ctatgatttc
    26641 tggattatac tgatcaatag tttgtttaac agcttcatac caaactgtat ctcctgtaaa
    26701 gtatagtgtc ttctcagtcg aatgtttgaa aacaataccg caaacattac ctacataatt
    26761 caagatttct cctctgccat gtttgccttt tgttttaacc aattgtatag attcaaaaac
    26821 tgtgtcttct cgtagtacct ccacattttt aaaaccatat agtcgaattt cattcgcatc
    26881 attttcatct tgcacaaata attttatttc tttaggtagg acctctttcg ctatatcgtc
    26941 ccaatgatct agatgtaaat gtgttacaat aacagcatca ataccgttga taatatcttc
    27001 gactggcatt ggcaaatcaa ctagaggatt catttgatct tttcttggtg atggaaaagg
    27061 acctttcgaa ataaatggtg gaagtgttcc tttttccgct aacattggat caattaaaaa
    27121 ttttttacct ccatagtcta agatagctgt tgcattacga atgtgatgta tattcataaa
    27181 cgttgtctcc tttttgttga tatgaaatat ttttagtata attcaattcc atacaataaa
    27241 taaaccgaac aaaaaaagtc ttttactatt tttacttaat ttatgaaagg ttgtttacca
    27301 tgttagacca aacagatata aatatcattg aggaactatc aaaaaatagt cgaatcacaa
    27361 tgaaagaact tggagaaaaa gtacatttga ctggacccgc tgtctcggcg agagtgacaa
    27421 aactagagga aagtggagtt attgaaaatt atacagtaaa attaaatatg gaaaagctag
    27481 ggttttcgat tcacgctttt ttaattataa ttacgcaaaa tttaaatcat aaaccctatt
    27541 tatcatttat taaaaatcat gaaaaattct tgattagaaa ttataagatt agtggagggg
    27601 gctgttatct tttggaatgt agatttactt caaaaaaatc aatgaacagc tttttggaac
    27661 agcttaatga atatgcgaat tataaattat ctattgttat agattaataa taaaactagc
    27721 agatggtaaa aatactaata tgcgagacac acattcaacc ataactatat aacttatcaa
    27781 tttaaaacta aactgatgga aacaagtaag gcaaaaacat ttatattttg ccctacttat
    27841 ttttttaatt aaattcattg atgattcata tttagaaaat tctatgaagg ccaaatgagt
    27901 atcct
//
LOCUS       DAFLWC010000032        27415 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.033, whole genome shotgun sequence.
ACCESSION   DAFLWC010000032 DAFLWC010000000
VERSION     DAFLWC010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.033"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(161..2158)
                     /gene="tkt"
                     /locus_tag="L1V17_001271"
     CDS             complement(161..2158)
                     /gene="tkt"
                     /locus_tag="L1V17_001271"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBN1236050.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2260..2511)
                     /locus_tag="L1V17_001272"
     CDS             complement(2260..2511)
                     /locus_tag="L1V17_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HBN1236051.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2658..3281
                     /gene="lexA"
                     /locus_tag="L1V17_001273"
     CDS             2658..3281
                     /gene="lexA"
                     /locus_tag="L1V17_001273"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBN1236052.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3461..3679
                     /locus_tag="L1V17_001274"
     CDS             3461..3679
                     /locus_tag="L1V17_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236053.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3968..4480)
                     /locus_tag="L1V17_001275"
     CDS             complement(3968..4480)
                     /locus_tag="L1V17_001275"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBN1236054.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4494..6791)
                     /gene="recJ"
                     /locus_tag="L1V17_001276"
     CDS             complement(4494..6791)
                     /gene="recJ"
                     /locus_tag="L1V17_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBN1236055.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6933..7376)
                     /locus_tag="L1V17_001277"
     CDS             complement(6933..7376)
                     /locus_tag="L1V17_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HBN1236056.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7377..8165)
                     /locus_tag="L1V17_001278"
     CDS             complement(7377..8165)
                     /locus_tag="L1V17_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1236057.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8162..9103)
                     /locus_tag="L1V17_001279"
     CDS             complement(8162..9103)
                     /locus_tag="L1V17_001279"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBN1236058.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9280..9867)
                     /locus_tag="L1V17_001280"
     CDS             complement(9280..9867)
                     /locus_tag="L1V17_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HBN1236059.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10088..11395)
                     /gene="obgE"
                     /locus_tag="L1V17_001281"
     CDS             complement(10088..11395)
                     /gene="obgE"
                     /locus_tag="L1V17_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBN1236060.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11689..12699
                     /gene="gap"
                     /locus_tag="L1V17_001282"
     CDS             11689..12699
                     /gene="gap"
                     /locus_tag="L1V17_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBN1236061.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12784..13719)
                     /locus_tag="L1V17_001283"
     CDS             complement(12784..13719)
                     /locus_tag="L1V17_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1236062.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            13905..14864
                     /locus_tag="L1V17_001284"
     CDS             13905..14864
                     /locus_tag="L1V17_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HBN1236063.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRK
                     VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            complement(14950..16044)
                     /locus_tag="L1V17_001285"
     CDS             complement(14950..16044)
                     /locus_tag="L1V17_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBN1236064.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            16233..16994
                     /locus_tag="L1V17_001286"
     CDS             16233..16994
                     /locus_tag="L1V17_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBN1236065.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            complement(17109..17549)
                     /gene="fabZ"
                     /locus_tag="L1V17_001287"
     CDS             complement(17109..17549)
                     /gene="fabZ"
                     /locus_tag="L1V17_001287"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBN1236066.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            17769..18524
                     /gene="fabI"
                     /locus_tag="L1V17_001288"
     CDS             17769..18524
                     /gene="fabI"
                     /locus_tag="L1V17_001288"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HBN1236067.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            complement(18634..19647)
                     /locus_tag="L1V17_001289"
     CDS             complement(18634..19647)
                     /locus_tag="L1V17_001289"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HBN1236068.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            19812..20732
                     /locus_tag="L1V17_001290"
     CDS             19812..20732
                     /locus_tag="L1V17_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HBN1236069.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            complement(21012..21512)
                     /locus_tag="L1V17_001291"
     CDS             complement(21012..21512)
                     /locus_tag="L1V17_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBN1236070.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(21619..22137)
                     /locus_tag="L1V17_001292"
     CDS             complement(21619..22137)
                     /locus_tag="L1V17_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBN1236071.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            complement(22138..23493)
                     /gene="rph"
                     /locus_tag="L1V17_001293"
     CDS             complement(22138..23493)
                     /gene="rph"
                     /locus_tag="L1V17_001293"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBN1236072.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            complement(23496..24317)
                     /gene="racE"
                     /locus_tag="L1V17_001294"
     CDS             complement(23496..24317)
                     /gene="racE"
                     /locus_tag="L1V17_001294"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBN1236073.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            complement(24479..25135)
                     /locus_tag="L1V17_001295"
     CDS             complement(24479..25135)
                     /locus_tag="L1V17_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBN1236074.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            complement(25151..25798)
                     /locus_tag="L1V17_001296"
     CDS             complement(25151..25798)
                     /locus_tag="L1V17_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBN1236075.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            complement(25811..26626)
                     /locus_tag="L1V17_001297"
     CDS             complement(25811..26626)
                     /locus_tag="L1V17_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBN1236076.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            complement(26640..27377)
                     /locus_tag="L1V17_001298"
     CDS             complement(26640..27377)
                     /locus_tag="L1V17_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBN1236077.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
BASE COUNT         7875 a         5929 c         4797 g         8814 t
ORIGIN      
        1 tcaagaaaca caaactaatc cgaagaattc tttgttttgt catttaaatg taacatagcc
       61 gaaaacgaaa agtaatattg atttattctt ctaacacata aagaacagct gtctccaact
      121 tgcagacagc tgttcttatc agtcaaacaa ttgcttggat ctatgatagt tgattgtacg
      181 tattcacgac attttctact gtaaatccaa attcttctaa aattttagtg ccaggggcag
      241 atgcaccgaa atgatcgatt gtaatcgttg cgccctctgt tcctacgtag cgttcccatc
      301 caaatgatgc agcagcttcg atagccacac gtttcttcac tgatttagga agtacacttt
      361 ctttatattc agaagattgt ttttcaaaga ggtcaaagct tggcatagaa acaacagaaa
      421 catctttgcc tttttcagcc aattcttttt gagctttcac agccaaatca acttcagaac
      481 ctgttgcaat caaaatacct tctggtgttt ctccttgtga tggagaaaga acatacgcgc
      541 cttttttcac catttcatct gctacttctt ttgtagaagg caatactgga aggttttgac
      601 gactcaatac aaggatagta ggcgcatctg ttgtctccat cgctactttc caagcagcac
      661 gtgtttcatt tccgtctgcc ggacgaatca cttgaacacc aggcatgcag cgaacagatg
      721 ctagttgttc aatcggttcg tgcgttggtc cgtcttctcc gacagcaacc gagtcatgtg
      781 ttaagacgta aacaacagga gtatgttgga ttgctgctaa acgaactgct ggtcttagat
      841 aatcgacaaa gacaaagaat gttccaccgt agatacgagt tccgccatga agttggatac
      901 cattcatagc cgaagccatt gcaaattcgc ggacaccgaa ccagatgttg cgtccttcat
      961 aatgttcagg agtgaaatct ttatctgcag ccaccattgt attattggaa cctgacaagt
     1021 ccgctgaacc accccagaag cttggtatag ctttcgataa ttcttggatg acttctttac
     1081 ttgaaacacg gcttgcttga ctgcttccaa cttcataagt tggcaattct gcatcccagt
     1141 tttctggtag tttgccatca aaagcatctt caaattgttg tgctaattca ggataagctt
     1201 ttttataatt ggcaaacatt tcattccatg catcttcagc tttttgtcct tcttctatca
     1261 tcgtttgatg gaagcgggca gctacttctt ctggaacagt gaaatctgga tactcccaac
     1321 cataaacttc tttagccatc ttgatgccat cttcaccaag aggagcacca tgaacagcag
     1381 atgttccttc tttaggagca ccatagccga tgactgtttt tacttcgatc aatgttggtt
     1441 tgtctgtttc agcttttgct tcttcaatcg ctttagagat tgcttctagg tcatttccgt
     1501 ctttcactaa gatatgttgc cagccatatg cttcatagcg agcaccaacg ttttctgtga
     1561 aagcttttga agttggaccg tctagtgaaa tatcgtttga atcgtataaa acgatcaatt
     1621 tccctagttt catatgacct gccatcgaac ttgcttcttg agatacccct tccatcaagt
     1681 ctccgtcacc gcatattgca tacgtatagt gatccatcac attaaagttt tctttgttat
     1741 acgttgctgc aaggtgcgct tctgccattg ccataccgac agccattgca atcccttgtc
     1801 ctaatggccc tgtagtggct tctacaccat ctgtatgatg tacttcagga tgtcctggtg
     1861 ttttagaatc ccattgacgg aattgtttca aatcatcgat tgtcacttga tagccagcta
     1921 aatgaagcaa gctatacaac attgctgacc catgtcctgc cgaaagaacg aaacggtcgc
     1981 ggtcagccca gttttttgat gtcgttggat ttactttcag gtgttttgtc cataacgcat
     2041 atgccatagg tgctgcgccc atcggcaatc caggatgtcc tgagtttgct ttttggactg
     2101 cttcaatact taatgtacga attgtgttaa cgccaagttg gtcaattttg tcaaacaaaa
     2161 taacccctcc tattaattta ggtttttttt acctttattt cttacacttt cattctataa
     2221 gatgtcacac gaaaaagcaa tctttttcag tattttttac taaaagttgt catttcggtt
     2281 gtgtaagcct tttttctttt ggatttcttt taatttttcc ggggtcacgt cattgccctc
     2341 aggatcgacg actttcattc cttcgatatg atgacgcata ccggaacgaa aagcttccaa
     2401 atactctttg cgcaagttga tttgttcttg ttcttcggct tttgagagac cattttcctt
     2461 ctttttacgt gcaagttcat tgatccgctc tattttttca ggtgacagca tgctcagccc
     2521 tccttttact ctccttcata ttatataaaa actgaaaaaa aaacaactag ataaactaaa
     2581 taaaatacga acattcgttt gatttagcgc tttttatatg gtactattta tttatcaagt
     2641 gaaagaaggt gtaccttgtg gcccgacaaa ctgaatcaag acaaatcgaa gtcttacgat
     2701 atatccatga acaagtaacc caaaaaggat acccgccgac tgtccgtgaa atcggggaag
     2761 ctgttcagct ttcttctact tctactgttc acggtcatct tgcacggctt gaaaaaaaag
     2821 ggtttatcca aagagatccg acgaaacctc gtgcaatcga gttgacaaaa caaggtttag
     2881 aaaagattgg gattcgtcca acaactattc cagtacttgg cgtcgtaaca gctggagaac
     2941 ccattttagc agtagaggat gcttcagact tctttccaat ccctcctaat ctttcttccg
     3001 aagaaggcag tctctttatg ctgacaattc gtggagatag tatgatcaat gctgggatat
     3061 tggatggtga caacgtgatc gttcggaagc aagaaactgc tcaaaatggc gatattgtca
     3121 ttgcaatgac tgccgaggac gaagcgactt gcaaacgatt ctataaagaa aaaaactttt
     3181 tccgtctgca gcctgaaaac gacttgctcg aaccaatcat cttagatcaa gtatctatat
     3241 taggacgagt agtaggactt tatcgtagtc atatctatta attgctacta attaaaagaa
     3301 aactttttaa aaagagtttg agacgttggt ctcaaactct tttttcgccc gggttcttct
     3361 tctttcaaat ttttatcact tccctcttta caaaccgaac aaatattcgt atactaaata
     3421 tacgaacaat tgttcgcata aattaaagag gtgagaattc atgaaatcaa tgagacgtct
     3481 tggcttagta ttaactgttt tgtttttagg tattattatt ggtaatttcg gcatacgtcc
     3541 agctttactt gtgtttgttc cgttatttac tttgtggttc atgttgtggg atgaaaagaa
     3601 gtaccgtcaa tctgagcggc gcagaattca tgaagatcat ttctatcatg agccctacta
     3661 cagatccagg caatcataat aaggattgac tgctaattat tcaaaagaca agaagttaaa
     3721 cttttacggg ggtgtgacaa aaatcggtca catccttttt ttcgaataaa cggtgttcta
     3781 aagccagttt ttcggtatta agtcaaattg cggaaaaagt gattttttaa acttctactg
     3841 gtctttgctt gtttccattt ataaaaaaat agcgaccctc aaaagtcaga tagagaatct
     3901 gacttttgag ggtcgcttta aaatcgcttc tttaagaata acatcaagaa tagcttcttt
     3961 tttctgctta atattccatt aatgtaatga tgtcatatcc tttgattttg tcgcgtccat
     4021 ggagatccat caattcgatc aaaaatgcgc agcctacgac tacaccgcct aattgttcga
     4081 tcagttcgat cgtcgctttg attgttcctc cagtagctag caaatcgtca caaatcagca
     4141 cacgttgacc tggtttaatg gcatccttat gcaatgtcaa tgtatctgtt ccatattcta
     4201 atccataagt cacttcgatg gtttctcgag gtaacttccc ttttttgcgg actggggcaa
     4261 aaccgactcc taactcataa gcaacaggac atcctacgat gaatccacgg gcttctggcc
     4321 caactaccat atcaattcgt ttttcttttg cataatttac gatttgttta gtagcttccc
     4381 gataagcgtc accatctgcc atcagtgggg aaatatctcg aaacacaatt ccttttgacg
     4441 gatagtcggg aatactggca atataatctt ttaaatccac tctttgtttc ctcctaggtt
     4501 gttaaccatt tctttatggt aggaatatcg ctcaaaagca aaaattcctc aactttgatt
     4561 ttattgagcc gtcgctggta taatctgctc tcagtcaaag gatgactttc tgggctagcg
     4621 actttttgta aaacaccgtt ctctattgta acaaatttca attcaaaaaa cacctgtatc
     4681 ataaaaatta ataatttttc agggatacgc aaatattgag ctattgcttt tattttatga
     4741 cgtatatcaa ttcgttcttg agaatggatc aatttaaaca attttgcgta ctgttctctt
     4801 gtgcctaccc cattcaaata ggcctcatca ggtgaaatcc ccatcagata aacacgattg
     4861 aatgaataag accgaaaaac ttctttcaga tccgctaaat catctggaca atccataaca
     4921 actagagagt ttggttttct tttttcaatt attgccttta cagaatctag tccttcgaaa
     4981 acaatcgcag cttcctggat aatctcaggc acgaatttca acgtcgaaga atcaaatgct
     5041 aaataaaggc taccttccga cgttcggctc tgttcacgga aacgttttgc ccgccaatca
     5101 aatacttgca gaccacccac agaaaaatca gataccatca gctgcggttt cttacgcccg
     5161 ttccattcat tgatcgaaag ctttcctacc acatctacct gattattcag cagttcttct
     5221 tcttgagtac caaaaccaaa agcgaccgca tcaagctgac tcgatgcatc ggaaaggaca
     5281 aatttcagat gctgttggtt tgctccgatt cttttgatat tttctgcttg gacttgtcga
     5341 aataaaaact gaggcaaagg attatccgta ccaaatggcg ccaatagttt cagctcatca
     5401 attcgctcta ctgttacttc atttggcagc aatacttcat caattctcaa ctcaggccct
     5461 ctcatcaagt caatttgatg atcgactata tattggttca tcttctcctg tagtatagtg
     5521 acattttcac ttggcatcgt taaaccgact gctgcatgat gtcctccgaa gtaagtaaat
     5581 aaatctcgca tctggtcaag catttcaaaa agattcaagg cttcaatact acgtccagat
     5641 cctttagctg atccatcttc ttttaaagta aggacaagcg ttggtttacc cgtttcattc
     5701 attattttcc cagcaacaat gcccaaaacg ccttcatgcc atcctcggtt taccaataga
     5761 tggatatgat tctccttatt gaccatcgct aatgcttctt gtgttatctg ctctacgatt
     5821 gcttttcttt cttcattgat ctcattcaat ttttttgctt gaacggatgc ttcctcttca
     5881 tcaaacgtcg caagtaacga gacggcagga cgtggatcgc ccatccgacc gattgcattt
     5941 agtctgggag caatcgaaaa accgatcgtt gtttcgtctg cgtccctcat ttttacgccg
     6001 ctttcttcaa atagcgcctg aagtcctatc cgttctgaat gatgaatggc atcgattcct
     6061 aatgaaacaa ggattcgatt ctcatcagtc aatgaaacta aatcggcgat cgttcctatc
     6121 gctactaaat ccaaaaattc tgcaggcggt tcttccaata atgcagaagc tactttgaat
     6181 gctactccga ctcctgccaa atctggaaat ggatagtgcc ccgctggatg acgagggtga
     6241 acaatcgcat aagcgtctgg taaattctca ggtagttcgt gatgatctgt aatgatcacg
     6301 tctacaccag cttgctgagc gtatgctacc gcatcatttc ctgctacccc gttatcaaca
     6361 gtgatgatca actggattcc ttcttcgatc ttttcttggt ataccgattg gtttggtcca
     6421 tacccatgct caaatcgatt tggcaggaat acttctactt ctgcaccaag taattccagt
     6481 gtttctttca ttaccgttgc actggtgatc ccatctgcgt cataatcacc gtaaacgagg
     6541 attttttctc cactgattac agcttcttgg attcggctga ttgctttatc catatcgtgt
     6601 atcagatacg gatcatgtaa ttcttgttcc tttggatgta aaaatcggtt gatatccttt
     6661 tcctcatggt aacctctttg ccacagtaac ttaccgacaa atggagataa tttcagttca
     6721 cggatcattt ggagaaagga ttcagaaggc tctgtctcgc ttaacttcca atcaaaattt
     6781 gcttgtctca ctttctcact cctaacttag ttattatagc aaaggaaatc agcaaaaaaa
     6841 agcagaaaga aagaataaaa acagatcaga tccgctagac agatgttcag caggacctga
     6901 tcttttgtac gaccatttat gaaatatccc tattagtcaa aataattgaa gctttgtttg
     6961 ggcgattgag ttttttgttc ttccggcgct ttcaattgac tgatttgtgc ggttttcgct
     7021 tgtaactccg cctgataagc agcttccaac tccgcacgtt cgtttctaaa ctcgcgttgc
     7081 tgttcttctt ttgcttcttc aattttcttt tgaagttctg tttgatattc tgacatttcc
     7141 tgagtcagct gtttgatttg ctttttttgc tgccatagtg ttgccgaagc agtcaaaaat
     7201 acaatcagtg caccaatcag cgcagaaccg atgatcacta agatcaatgg cgcagaaaag
     7261 gaagtgaagc caaaacttac aggaacattt ttattgttca atacagcaaa aagaacaata
     7321 atcaaaacta aaacaaatcc aagaatcaca ttgctttgct ttttcaattc cttcacctac
     7381 tttttgttaa aaattccgct ggctaaataa tcaccaatcg ttggaaacag cgtataaaat
     7441 tttgatgcaa cttctaaaat aaacggttga ttgatttccc gttttggatg tctcatattg
     7501 cggacgatca tttttgccaa cttggcaggt tctaaaacga tttgtccgac tttttccaaa
     7561 tagcttccgc ttggatcagc cttatcgaag aaatttgtct cgattggacc tggattcact
     7621 gtcgtaacag ctacgccaag tggtttcaat tctaatcgca aagcgttgga gaagccaagg
     7681 actgcaaatt tcgtggcaga ataaaccgtt gattttgcag ttgccatttt tccagccata
     7741 gaggcgatat taatgatatg accttgtctt ctttctgcca tatcgatcgc aaatttttgt
     7801 gtcaaaacca tcattcctaa gatgttgact tcaaacatat cgtatgcttt tccaaggtcg
     7861 aatgtaagga agtcttcgaa aatcccaaaa cccgcattgt ttaccagaat atcgacgcgc
     7921 ccgacttctt ccatcacctt ttcatataat tcgtccacgc tttcaggatt gctgacgtct
     7981 accttgaaag cataagcctc tttgccgctc aagcgtctgc actcgtctct gacaccttct
     8041 acaaatgcca ttcttcgtgc gcaacttata acgattgctc cttgctttgc tgcttcataa
     8101 cagatttgtg cgcccagacc gcctgaacta cctgttacta aaacaacttt atcttctaaa
     8161 ttcatgcctc ttcctcctcg cgaaatggaa tctcaatgct atcaaaatct ttcataatcg
     8221 tcgtgttttc aaacacttct tgtgcttctt tttcaagctc taaagctgct tttcctaaat
     8281 atctcgcact gatatgagta agtagcagcc gttttgcctg cgcttctttt gcaacttcag
     8341 cagcttgatg agtcgtggaa tggaaatagt tgtgcgccat tcttgcttca tctttattaa
     8401 atgtgctttc atgtaccaga atatcgctat tttccgcaag cacaacggaa ttatgtgttt
     8461 ttctcgtatc gcctaaaata gtcacgattc gtcctttttt atctggacct acgaaatctt
     8521 ttccattgat cgtccgccca tcttctagtt ggatcgtttc accttgcttc agtttgccgt
     8581 acagtggtcc agctggaata cctaattctt ttagacgatc cacctgcaat tctcctttat
     8641 gatcatgttc aaccacacga taaccaaaac tgtcgatccc atgatttagt ttttttgtat
     8701 aaacagaaaa ttgctgatca gtaaaaatcg gggctgtttc atttagctca atgaatttca
     8761 gcggataact taaacgcgtt tgcgaaatac ctaaagagac ttttatgtat tcctctatcc
     8821 cttttggccc gtaaatctct aatggcgtat ccccaccttg aaatgaccgg ctgctgatga
     8881 gcccgggaag tccaaaaata tgatcgccgt gtaaatgtgt aatgaaaatt ttaccgattt
     8941 ttctcggacg aatagtcgtt cgcaaaatct gcatttgcgt gccttcgcca cagtcgaaca
     9001 accaaacttc attgcgctcg tctaaaagtt tcaatgctat acttgtcaca tttctatgtt
     9061 ttgcaggaac acctgcacct gttcctaaaa attgtaattc cataatctac ctgactttct
     9121 ttaagttcct ctttaatttt agggtaaaaa gaagggataa tcaaccgtaa gtcgagaatg
     9181 ggttcaaatt aaaaataacg ttctaaagcg atagcgtttt ctttgaaaat tactataaaa
     9241 acagcagcga acccgtttga gatcctctgc tgttttttat taatttgaag atccagaact
     9301 ttcattgtcg ttggaagttt gcggatgttt gtccttccaa gtcttttgtg cagcttcttt
     9361 cgcatgattt tcagcttctt tcgcatcatg cacatctttt tcgacatctt cataatccaa
     9421 gcgagtaatt tctccgccta attccatcat taccaattga ttcagtgggc gattgtcctc
     9481 ttcatcagca atcaagatca gtcctgtagc tccttcaccg attttatttc ctacaaagtc
     9541 gaacacggtc tgggcatctt ttatttcttt ggcatcttgt gtcgcaccga tcattcctcc
     9601 ggcaaaccat cctaataaaa tccctagcgg accacctaat acaccaacca acattccgat
     9661 taatccaccc gtagaagatt tgttattacc ggtaaagtcg ataaaatctt ctattttgaa
     9721 ttgatgtgtc ccattaggat catggctgac aactgccatc tgttctcctt taatcgaacg
     9781 aacagcatgt aactttttga tttctgaaaa tgcctgatat gcctggcttt ctacttgaaa
     9841 atttaaaatg attactcgtt tgctcattaa aaacgcccct ttcatacctt cttgttattt
     9901 attttacctt taattgaaaa ataagaaaag aaaagcactc tttttttcca ataaaatagg
     9961 gctgtgacaa aagtcgtatc acagctcctt tttccgaata aacggcgttc ttgaagctga
    10021 tcacttctgt cacaacctcc cttaaatctg aatctatatt ttttggtatt tgtttttatt
    10081 tgcttgccta ttcgacaaat tcaaattcaa actcaccgat acgtacaagg tcgccatctt
    10141 tcgcaccgcg tgcccgaaga gcttcatcca cacccatacc acgtaattga cgagcaaaac
    10201 gcatcactgt ttcatcatga tcgaaattcg tcatttggaa taatttttcg atcttctcac
    10261 cagataagat ccacgttgca tctgaatcac gatcgatttg gaactcagga ccttctggat
    10321 tgaatccata gtgtacagtt tcttcttcca gttcttcttc gtacaatggg aattctggcg
    10381 ttacttctaa caaatctgct gtagcattca ataacgcgtc caatccttgt cgagtcactc
    10441 cagaaattgg aaatactggg atgtcatcag caaattcatc ttctttttcc ttgttcagct
    10501 gttctttgaa tttcactaga ttttccggtg catccggcat atccattttg tttgccacga
    10561 tgatttgcgg acgctctagc aagcgtaagt tataagtaga taattctttg ttgatggcaa
    10621 gatagtcttc ataaggatct cgtccttcca tcccactcat atcgatcaca tgtaaaatta
    10681 ctcgtgttct ttcgatatga cgaaggaatt gtgtacccag cccaacacct tgcgaagctc
    10741 cttcaatcaa gcctggcaag tctgctgcgg caaaacttct gccatcactt gtagtaacca
    10801 ttcctagatt aggtacgagc gtcgtgaaat gataagcgcc gatttttgga cgagcagatg
    10861 aaataacgga tagtaaagtc gatttcccga cagatggaaa acctacaagt ccaacgtctg
    10921 ccaatacttt caattctagt tcgatttttc gctcttgtcc tggttcaccg ttttcagcaa
    10981 tttccggtgc aggattccga ggagaggcaa aacggatatt ccctcgtcca ccgcgtccac
    11041 cttttgccac aactagtgtt tgaccatttt caattaaatc tcctaaaaga gcaccagtct
    11101 ccgcatctcg gacagtggtt ccttgtggta ctttaacata ggtatcttct gaaccacgac
    11161 cgtgcatccc tttactcatc ccattttcac ctggctgcgc tttgaaatgg cgattgaacc
    11221 gaaaatccat caatgtacgt aacccttcat cgacgatcaa gatgacatcg ccgccacgac
    11281 caccgtctcc gccagccggt ccgccgtcag gaacgtattt ttcgcgacga aatgcaacca
    11341 ttccgtctcc gcccttgcca gctttcacat cgatcgttac ttgatctaaa aacatggaca
    11401 taattaagtc ctcctattat tcatttattt atttgactgc ctgaatttcc acaataaaca
    11461 aaagtcttac ttattttatc ggtgaaatct gattttgtct atcatttcag caaaaagatt
    11521 gtttaccttc ttcttttttt atcatttggt aaggtttcca accttttttc tgctaccaag
    11581 tataattttt tgacaaaata ttctttgcgt agcagaataa cagtgtatta attgtattaa
    11641 ttgaggatgc cgtttcacag cacccctaat aaaggaggaa cttttgatat gacagtaaaa
    11701 gtaggtatta acggatttgg gcgtattggc cgtctggctt tccgccgcat caaagaagtc
    11761 tcagatgata ttgaagtagt agcaatcaac gacttaacaa gtccaactat gttagcacaa
    11821 ttattgcaat ttgactctac tcatggtact tatcctggca cagttactgc aacagaagac
    11881 tcaatcgtag tggatggcga agcaactcgt gtttatgcag aacccgacgc aagcaaaatc
    11941 ccttgggcaa aagaaaacgg tgtagatatc gtactagaat gtactggttt ttatacatct
    12001 gaagaaaaag caaaagcgca tttagatgct ggtgtcaaac gagtagttat ttctgcccca
    12061 gctggtgcta tgaaaaccat cgtctataac gtcaatgatg atacattaga tgaaaacgac
    12121 aaaatcatct cagcaggttc atgtacaaca aactgtttag cacctatggc ttatttctta
    12181 aataatgaat ttgggatcga agttggtaca atgacaacag ttcatgccta cacttccaca
    12241 caaatgctct tagatggacc tgtaaaaggc ggtaatttgc gtgctgctcg ttcagctgct
    12301 gacaatacta tcccacattc tactggtgct gcgaaagcaa tcggcttagt tatccctgag
    12361 ctacaaggaa aattacaagg acacgcacaa cgtgttccag tcgttgatgg ttcattaact
    12421 gaattggttt cagtattgaa aacaaaagta actgctgatc aagtaaacga agcaatcaaa
    12481 aaacacacag ttgacaatcc ttcattcggg tatgatgacc gtcaaatcgt ttctagcgat
    12541 gtcattggaa caactcaagg ttcgatcttt gacccaacgc aaacagaagt aacaactgct
    12601 ggtgatttcc aacttgttaa aactgttgca tggtatgaca atgagtatgg atttacttgc
    12661 caaatgattc gcttactaga aaaattcgct aacttgtaat ttgatagatc aatcgataaa
    12721 agaagccttt gactggatcc agtcaaaggc ttctttcttt tcatccccta cttttaaact
    12781 cgttcaatga acatattggc ttaaaaattg ttggactact tgctgatatt tttcaggatc
    12841 tgtcttgtat gcttccgcat gctcggctcc ttttacaaca tacttttctt ttggtccctt
    12901 cgttgcacga tagaccttat ctaacatttc aaatggtaca aatgtatctt cgtctccatg
    12961 tataaagagc attgggcgct ggtttttctt caattgttcc actgcatttg cttcaccgaa
    13021 aaagtagcca gcacggactt ttgtcactag actcgttact tgcataagcg gaaatgctgg
    13081 aagactaaac atatcgtcta gctgataagc aagctcatca tgaacggaag aataaccgca
    13141 atcttcaatg attgctttca cattatctgg tagtttttct ccgctagtca tcataactgt
    13201 tgctgctccc atgctgacac cgtatagaac gatttcttgc gattttccat tgttttctag
    13261 cactttgttt atccactgta catagtcttt acgctctggc catccaaatc caatgtaatc
    13321 cccttcgctt tttccatgtc ctcttgcatc aggaacaagg acattgtaac ccatatcatg
    13381 aaacatcttt gcgtaattgg tcatcgtttc agcgtttccc atatagccat gagccacaag
    13441 agctgttttt tcacttttcg tttcagcagg aagataaatc gctgataatt tcagaccgtc
    13501 ttttgaagtg atggtccaat cgcttcggtt ttcttttgaa ctaaaccatt tatgtgcatc
    13561 cgtttctttg gatgtctgtg ttgtaccagg tgtatcttcg tctaaaaagt ctttctcaga
    13621 aggcacaaca gcataattat aaaaataatt ccctgcaaac actaacgcaa caatcagagc
    13681 taaagcgacg cctaaaagga ttttcatcca aagtttcata aatcatccat ctcatttctc
    13741 ttttttcata taaccttgaa ttagtataat caaagaatct ctactatgca atgttcattt
    13801 ttataacccg cgaattgtaa aattaagtta gaaaaataaa aaggcattta tggtacactc
    13861 aaattgtatt tccgacgaaa gaaaacaaag gagtgtaacc ataaatgacc tacaaacatc
    13921 ttaccataga cgaactgaca atgatagaat catattatct tcaacataat aagccggttg
    13981 aaatcgctaa ccgaatggga cgtgctatac aaactattta taatgtagtc aataagttca
    14041 agcaaggcaa gactgctctt gattattggc accagtataa agaaaataag aaaaaatgtg
    14101 gtagaaaagt cattcaatta cctgctcatg aagtagatta cattaaagag aaagtcactc
    14161 ttggttggac gcctgacgtc attatcgggc gaaaagaaag gtctgtttca tgcggtatga
    14221 gaacacttta tcgtttattt tctaaaggaa tatttgatat tgacacacta ccgatgaaag
    14281 gtaaaagaaa acccaatggc catcaggaaa aacggggaaa acaacagtat cagcgctcaa
    14341 tccatgatcg acctgataat tatcctgatt tcaattctga gtttggtcac cttgaaggtg
    14401 atacgatcgt tggcattcat cataaaagtg ccgtcattac tttagttgaa agattatcta
    14461 aagtcattat cacgattaaa cccaacggcc gtaaggcatt agatattgaa actgccctta
    14521 atcaatggtt ttctcgcttc cctaaaaact tctttaaatc tattacgttt gactgtggaa
    14581 aagaattttc taactggaaa gccattagta accaacatga tattgatata tattttgcgg
    14641 accctggaac accttctcaa cgcccattaa acgagaattc taacgggatt ctgcgtcgta
    14701 atggactgcc gaaatcaatg gattttagaa aagtgaatca gacatttatt tccagtgtca
    14761 gcaatcaacg taatcatatt ccaagaaaat cattgaatta cagaacacca atcgaaatat
    14821 ttttgagcta tgtacaagaa gcattttatt ctagcttaat ttgacaaatc ataacctata
    14881 aaaaaacaaa ataaaaaagc agaaataact ggctatttct agcggattat ttctgcaata
    14941 actaattatc tattttttat tttcaattaa tttaaagctt gaccatggtt tcaaaaagtc
    15001 aaggaggaat aattcgtcat cggagattct tcctacaaca ttgacacgtc cgtcgttttt
    15061 catatccttc aaggcgattt gtgtttctcc tttgtattga ccgtaccctt cattgtcaat
    15121 cagtacatcc ccatgatgca tatctcgcgt attatgaggc gggaaatctt tatctttgta
    15181 gtatacacga gtcatcgttg aacgaaggat atattctgag cgatcccctc gataactatg
    15241 aaggttatca aacaagcaga ttcgttcgtt ttctgtaata ccttcttccg tatctacttt
    15301 caatgttgga taatccgcgt taaatgcttc tgccatttct ttcaattctt cttcacttgc
    15361 gtacgcattt ccaatagaaa tatcatcaat caatcctgta aggattaaat gcttcacttg
    15421 tgtcgcaatt tcaagatctc ggtggtcttc cagcgtgcac aagccatctt gcgtaggcca
    15481 agggccaaac tcagcagatt gcgaattgac gaatgccatc gtattcaaat tatattttct
    15541 gaatttttct gaacaaaaaa caaagtgttc gtatcctaaa ccagagtatc gatgaggata
    15601 aaaattatga gaacctaata aattatccgt gtttggcgaa taactcatga tgttgtcaac
    15661 gtaattcgtg cccgaactca tattgatctc gattttgata ccaaaaggat tgcgcgtcat
    15721 ttttgcttct tctgctcctg tgaatccgat atctaagcgg accccgtagg cacccatctt
    15781 atggaaaaaa gataagtcat cgtaagaaat ctccaactgt tcaaataacg ctggattgat
    15841 atcaaccatt acttccatgc ctaggctatt cgcgtaatca actacttctt taaattctga
    15901 aagaactttt tctttatcat cattgatctg cagcaaactg gtaaaaaccc gtttataccc
    15961 atacttatga gctaaatcca agtacgcttt gtccttttca aatgttgacc gttctggata
    16021 aatcgagatt cctaattttc ccatattacc atttcctcct gcatcttttc gtttttgtat
    16081 ccacttacat tatagcaaac acaaagtaaa tggtctacac cttttctttt tcttttaaaa
    16141 taaatgataa attccaataa tttaagtagg tattttccct ctattttgtt atcattaaag
    16201 ataacaaaat agtaaattgg aaaggaacag ttatgaagaa aaataaagtt attttaagta
    16261 ttagtttagc agcagcattg ctgtttgctg ctggttgttc tgcaaacaac acgacttctt
    16321 ctagttcgtc tacagaaagt tcaaaaagta catctactgc ggaaagcacg actgccagta
    16381 gcgtcgattt gaacgcattg gaattaccac aattgacgaa agatgtcgcc gaaaatgaag
    16441 atctggtcga aatggtgacg aataaaggca caatcaaaat caaattattt cccgaacacg
    16501 caccaaaagc ggttgaaaac tttatgacac atgcaaaaga cggttactac aacggactga
    16561 ctttccatcg cgtcatcaaa gatttcatga tccaaggtgg cgatcctaaa ggcgatggca
    16621 ctggagggga aagcatttgg ggagaaggat ttgaaacaga gatcaacaac cacctttata
    16681 atataagagg tgcgttatct atggctcgct cacaagatcc taacagtaac ggcagccagt
    16741 tctttatcgt tcaaaataca gatgatatgc atgatggtct tttaaaagac gactatcctc
    16801 aagcaatcat cgacgcttat aaaaacggcg gttatccttc actagatggc cattatactg
    16861 tcttcggcca agtgattgaa ggaatggatg tcgtggatgc tattgcaaat atcgaaacag
    16921 atagttcaga caaaccaaaa gaagaagtaa aaatcgataa aatcaatata ctgcaagaag
    16981 caaaacaaaa ataaaaaaat aacgtctgaa tcctgcatag atgacaacgt atgctaggat
    17041 tcaggcgtct tctttttaca taaaaagcaa gtaagcttcc ttttgttttg ctatatcagg
    17101 ttttatagtc aagcattttg gttgacgatg aacgtgaact cgcactcaca gactttttta
    17161 tcatctacat atgctgcaga taacgctgta ccgactgatc ccttcatttt ggtgatttca
    17221 aaatgacatt tcagcacatc tcctggaaca actttttgac ggaatttggc cttattgatc
    17281 ccaccgatat aagctctttt tcctagaaac tcttctgatt ttaggataag tatcgaacct
    17341 gcttgtgcca gtgtttctag aatcaacgca cccggcatca ctggattgtc aggaaagtga
    17401 ccttggaaaa aatcttcatt gattgttaca ttttttgtcg caacgatctt ttttcctggt
    17461 tctaaagtat ctacataatc aatataacaa ataggataac gattaggaat caattccatt
    17521 acttcagtag cagataatac gtaagacata attaaactcc ttctttcagg caattgccat
    17581 tttcattact ttgactatca aagtatcata ttcctaaata tttagcaatc tttttttaat
    17641 ttaagaaaaa atagtttgac aatcaaaaca ttttgactaa taattaagaa atcaagaagt
    17701 tattttagct attattctct atttttttac gactatcaaa tttttatcag aaacaaagga
    17761 gagtcattat gtcatttcta gaaggaaaaa aaatcgtcat tatgggcgtc gctaacaaaa
    17821 aaagcattgc ttggggttgt gctgaagcaa tgttgaaaca aggggcagaa attatctata
    17881 cttaccaaaa tgaacgaatg aaaaaatcat tagtcaaatt ggtcggcgaa gaagcattca
    17941 ctgtagaatg tgatgtttct agcgacgaaa gcatcgaaaa agcaatgaat gccatcggtg
    18001 aatatgctgg ggagatccac ggccttgtcc atgcagttgc ttacgccaac aaagaagaat
    18061 tgtccggaaa tgtgtctgat atttccagag acggctatca attagctcaa gatatcagca
    18121 gctactcttt aattgctgta tcaaaatacg cacaaccgtt tcttgcacca aacagcggga
    18181 tcgttagcat gacttatcta ggttcagaac gcgcaatccc gaattataac atgatgggta
    18241 ttgcgaaagc ttctcttgaa gctgctatcc gttatttggc agctgagttc tcgcctaaag
    18301 gaattcgggt caatggaatc tcagctgggg caatcaaaac attagctgtc acaggtgtta
    18361 aagactatca aaaactgatc cagttatctg aatctcgtac gcctgatcag caaggtgtga
    18421 cgatcgaaga agtcggtaat gcttgtgctt tcttaatcag cccactttcc agcggaatca
    18481 tcggtgatat tatctacgtt gacaaaggtg tccatctttc ataaactttt gttgcattct
    18541 ttaaagtaaa acatataaaa atcaggaaaa aactttttaa agtctcttcc tgattttttc
    18601 tttttacgtt tttttcaact cattactttg aaattattcc acgacttcaa tccagccttc
    18661 tggtgcttct atgtctccaa attgaatacc tgtcaattca tcatacaacc gttttgttac
    18721 tggtcctact tccgtttcac tataaaatac atgaagattg ttattgtgat aaatcccacc
    18781 gattggagaa ataacagccg ctgtaccaca tgcaccagct tctgcaaatt gatctagatc
    18841 atcaatgaaa atatctcctt caattgcttg cagtcctagt cgttcttcag ctaactgcaa
    18901 caaggaatat ttcgtgatac ttggtaagat agagggcgat tgcggagtga tgaattttcc
    18961 gtcttttgta attccaaaga aatttgctgc acctacttct tcgattttcg tatgtgtggc
    19021 tggatcaaga taaacacaat ctgagtaatc cagttctttt gcttctgttc ctggaagtaa
    19081 actcgctgcg taatttccgc cgacttttgc tgcaccagtc cccttaggag cagcacgatc
    19141 gtaatcagat acaataaaat tcgttggttt tagtccacct ttgaaatacg ctcctactgg
    19201 cgtacagaag acgacaaata aatattctgg agctggatgg acaccaatgt tttcaccgac
    19261 cccaatcagt aaagggcgca agtataatgt agcgcctgtt ccatagggcg gcacaaaatc
    19321 ttcatttgct tttaccactt gcttgacagc atcaacgaac atcttttcag ggaccattgg
    19381 catcagcaat cgtctagcac tttgattcat ccgtcgacta ttttgttcag gtcgaaagag
    19441 attgaccttg ccgtcttttc gacgataagc ttttagacct tcaaaacatt gctgaccata
    19501 atgaagcgct ggagagcctt catgaatcgt caggtaatta tcttctgtca attctccttc
    19561 ttcccattgt ccgtctttcc atttggcaat aaaacgccaa ggagttttga tataagaaaa
    19621 acctagattg ttccaatcga tttgcatata cttaccacct tcgttatttt ctccacattt
    19681 tatcattatc catattattt gtcattttat tttcagcttt tttccttcat tatagttatt
    19741 tttgctattt ccttttttga aaacttcttg gtacaataca gaaagaatca aattttagaa
    19801 aagaggattt tatgttttca ttattagcaa ctgccggtac gacagactct tctggcgaga
    19861 cattgacaga tcaagctgtc agcaaagtaa atgcgtttca gcggttttgg gacgggattg
    19921 attgggacgc cattttggct gcctttatcc aaaaaagttt atatctgatt tttttgatcg
    19981 tccttttttg gattcttcac cgtgtgggaa aatatctgat tgataagtct tttaatcagt
    20041 attctaaaaa agccattcta aacgagagcc gcttaaagac tttacatagt cttttaaata
    20101 ctatttttca ttataccctt ggtttctttt ttatctatgc aattttatct gctatcggtg
    20161 tgccgatcgg atcacttttg gctggtgccg gaattgcagg tgtggcaatc ggtcttggtg
    20221 cccaagggtt catgagtgat gttattaccg gattttttat tatcatggaa caacagatgg
    20281 atgttgggga ctacatcaag ctagcaaact taacgattga aggaaccgtc gtatctgttg
    20341 gtatccgtac ccttcagctg aaagcaacgg atggtactgt ccatttcatc ccgaatcgaa
    20401 acatcaccac gatcagcaat ctctctcgtg caaatatgca agtactttta gatattcgga
    20461 ttgttcctga agaaggatat gacaaaatct atgagatcat tgatcgagta aatcgtacat
    20521 tagctgaaaa ataccaagaa gagctccaaa ctgaaccttc tatctttgga ttagtggatc
    20581 ttggaaacag caattttgcg attcgtacgg tctgctacgc attgaacgga aaacaatatg
    20641 ccttaaaaga agagttcttg agctcctatg tcaaagaatt gacagcttct ggtttcacga
    20701 ttccgaacag tccaattgct gtcggaaaat aatttggaca aacgatgcaa cgaatctcac
    20761 taaaaagagc gtgggacaaa agtaaagaac acttttgtcc cacgctctaa acacgtataa
    20821 acggcggaag cagaagcaac tccttcggaa ataagctgaa attcacaaaa atttgaaaag
    20881 caattttcgt gaattccttc ttatttcttg gagttaaacg cttttgtccc agcctctttt
    20941 tcaagataaa gtcaaaactg gtacgctgtt ttttctactt attttttgat tatcttttag
    21001 tttctcgttc tttagctcac gatatcgatt tgttctttta attcttcgat tttcggagac
    21061 aatatattac gacgttctaa ttcatgcacc atgaagttta cggctttaag cagctctttt
    21121 cttgtaatga ttcctttgaa aatccgatct tctgtgacaa ccggtaaaaa aggcgaatcg
    21181 actaacaaat ggagtacttc ttctagttcc caattttcat caattgtcgg aacatctgtt
    21241 tctgtcacat cagcaaccgt tagtccttct aacgggtcca tgctgattgt ttgcaagtca
    21301 atcattttat tgaccacatc tgataaactt actagtccta caaagtgatc atcttttcct
    21361 aatacaggaa ttttggaata accgaccttc gataacacaa gtaaaccatg ggacaatgga
    21421 tgatgataca taacatttgc cacattttct gcaggaatca aaaacgtttc ctgattttcc
    21481 agcagcattt ctcttactat aggtccaatc atctgatggc ctccatttct atttcattca
    21541 acactactat tttaccgaaa ccggatgcaa aattcataaa ataaagctta tttttattaa
    21601 aaattagagt ttttttattc agcgctctct cgaaaaagaa aaggccaact cttcaactgc
    21661 ctgatgggca cggttatagt attgaacaga aatttggtca tctaaacttt cgataagagc
    21721 atatgatggg atttggatcg ggcctctagg ctgagaaatg ctaccaggat tcaaaaacag
    21781 gattttctga tccatctcac agcctatttg atgggtatga ccaaaaaaca ccatatcggc
    21841 agttgcagct cgagcttcga ttgctaactg tgtcaaacca aatcggacat tcgataaatg
    21901 accgtgagtc atgaatactg tatcctgacc agtttggatc acttttttct gttcgaatcc
    21961 tggtccataa tcacaattac cttgaaccac ttggaatgta tcccataatg ggtcagaagc
    22021 ttctaattcc gaatcaccac aatggaaaaa gatatccact tcagaacgat aacgatctac
    22081 taagtcaacg aggatatctc tgtctccatg attatcactt actactaaat accgcatcta
    22141 tctctctcct tccagccatt gtttccactc ggcactcaat tttttcattg cttgagcccg
    22201 atgactgatc ttgttttttt cttcgctcga taattctgct gctgtttgtt tcttaccttc
    22261 tgggataaat aaaggatcat acccaaagcc attttcgcca gatggtatac gggctactcg
    22321 accgggccat tccgcttcta ctacaaggct gtcttttttg ggtgccgcga atactaacgt
    22381 acaatggaat tgtgctgttc ttttttcatc cggcacatct gtcaattcat ataataattt
    22441 ggcgttattc cccgcatcac ttttttgttc ccctgcaaaa cgtgcagaat agattcctgg
    22501 cataccgcct aaagcatcca ctttcaaacc tgaatcatct gctaagactg gctgatcaag
    22561 caattgtgca atcgtttctg cttttaatcg ggcattttct tcaaatgtgc tgccagtttc
    22621 ttccacatct ggcaattcag gatagtcaag taatgttttt acatgatatc ccgcttcttt
    22681 gaacatattt cgaaactctt ctgcttttcc tggatttctt gtcgcaatga tgattgtttt
    22741 tgtttcttct atccgctcat cattttgagc aaactctgtt agcaaagcat gtttttgctc
    22801 tttgatcaaa tcttcaatcg cgttttttcc aaaaaagagc atttcattca actgttcacc
    22861 atcaaacgtt gcttcttctc cagttccttg aatctccacg aattttccag attctgtcat
    22921 tacaagattc atgtctacaa gtgctgcgga atcttcttgg taatccaaat ctgtgacgca
    22981 agtcccatct ggtaagattc ctacgctaac tgcagcaaga tgttctttta ttggatcttc
    23041 tgacaattct ttttctctta aaagtttttc aatggctaat ttcaatgcca caaatgcccc
    23101 agtgatactt gctgttctag taccgccatc cgcttggatc acatcgcagt ctacgatgat
    23161 actacgttct cctaattttt ccaagtctac tactgcacgc aaggaacgac caataagacg
    23221 ctggatttcc attgttctac cagaaagttt ccctttgctg ctttctctac gatttctcgt
    23281 actcgttgct cgaggcagca tactatattc tgctgtcacc catcctgttc ctgtttctct
    23341 caaaaaaggg ggaacagaat tttctattgt tgcagaacaa ataactgttg tatcaccaaa
    23401 acggatcact accgatcctt ctggatattt gaaaacattt gtttgaagct ccagtttgcg
    23461 aagctcttgg gcttttctcc cgtcatgacg catccttatt ttcctcccaa ttcgatatgt
    23521 tctacattta agtgtccgat tccaagccag tcttcagcta tttcctcgaa aagtttggca
    23581 gagccagttg tataaaactg gcataatgtc cgaccatttt gcggtgaatt gctcaaattg
    23641 aaataatcta acagcataga tacttcacct actgtttctg ctccagaatc gatcagttga
    23701 acattttctc ccattacatt ttgaatgatg gggcgtaata atggataatg ggtgcatccc
    23761 aaaatcaatg tatcgatttt tttagtggtt aaaggagcta atgtttctgc cacaattttt
    23821 ttcgccaccg atgaatggta ttcattactt tcgacaactg aaacaaattt gggacaagca
    23881 agacttgtca cagtcaattc tggtactttc tctttcagtg ctttttcata agcttgactt
    23941 tttaccgtac caatcgtacc gataatgcca acttgtttat tttgtgtttt ttttactgcc
    24001 gctctagtac cgggaaggat cacaccgatg actggaatag aaagagcagc tttgatttct
    24061 tctaaagcca ccgcagttgc ggtattgcag gcgatcacca gcatcttgat tccttgctcc
    24121 accagataat ccgtcatttc ccaagtatac tggattacct gttccgcggg tctagggcca
    24181 tatgggcagc gtgctgtgtc tcctacaaat aaaatatttt cattcggtaa ttgtttcagg
    24241 gcttctttta ctacagtcaa gccgccgaca cctgaatcaa taaatccgat agggcgatta
    24301 tctgtcaatc gtatcatcct ttttttcaat aaattctatc ctccctattg tgtacttttt
    24361 agcgtgaatt ttcaagtgct cttacttgct taaaacaatc gaaatctctt tttttcgaat
    24421 ggaaagagga aaagcggttg tgactttagt ttgccacaac cgctaaaaga atcatctatt
    24481 aataactgta ccgtctcttt tccaagtaac cggaaagcag agaaagcgcg taacatacca
    24541 cgaagtacat aagtgtcatg atgatgaaca tcggaagcac ataattggtg ttctgtccat
    24601 aaataatacg tgcctgatga gaaagttcag gtaaagaaat gattactgct aatgaagtat
    24661 ctttgatcag tgaaatcaat tggctcacaa ttgccgggat cattgattta aatgcttgcg
    24721 gtaacacgat cgttcgcatc gattctacat aagtcagtcc cgttgataat cctgcttcca
    24781 tctgtccttt tggaacagca ttgagtccag ctcggaaaat ttccgacaac atagctgact
    24841 caaaaatcgt taatgctgcg acagcggacc agaagatgtt catctgaatg ccgatttgag
    24901 gtaaggcaaa gtaagtgaag aaaatgatca ataataatgg aagattccgt ataatatcaa
    24961 tcactacacc aaggattttg gaaaagaaag ggatattcgc aaaacgaatc acacctgtca
    25021 gaccaccgat caagaaacta aaaatgatcg aaaacaatga aacttcaaca gtaaccttta
    25081 atccttccaa taaaaaacgg atattcatcc atgaaaaagc gccgctaaaa tccatgtatt
    25141 tcccctcctt ctatgaacga accgcccatt ttttctcaag ataaaccatt aagtaagata
    25201 acggtagcgt gataactaag taaaataacc caacgatgat atacgtatcg aaggtattga
    25261 atgtttcact agcgatcaag tctccttgat acatcaaatc taaaccagct acgattgcta
    25321 aaatagatga gttttttacg aggttgataa attggttgcc taatggcggg ataacgattt
    25381 tgaatgcttg cggtaaaaca atataacgca tgatttctga ataggtaaaa ccagaagata
    25441 gtcctgcttc tgtttgacct tttggtacgg tttgaatccc tgaacgtact gtttcagcaa
    25501 taaaagcaga tgtatagatc gttaatccaa tcgtacctgc ttggaatcca tctagattaa
    25561 accaataaat cggtacgaca acataaaaaa acatcacgat gattaataat ggaatgtttc
    25621 taaaaaattc tacatatgcc tttgctaagg cgctcactac tttattcttt gataattgga
    25681 agattgccat taacgttccg ataatcaaac taaacacaag tgctaagaca ctcgaaaaca
    25741 atgtgatctt gaacccgtcg acaaagattg gtccataagt ttgtatcaat tcgctcattg
    25801 cctctccccc ttactctact tttccttcag tttcatttgg aaaccatttt tgatagattt
    25861 tatcgtatgt gccatctgca tgcatttcct ctagcgcttg gttaacagct ttcaagaagt
    25921 tttcttgccc tttgttgatc gcaatcccgt aaggctcatt agtaaacgtt ccaccaacta
    25981 actcatactc tggattttca tctgcaatcc ctaacaaaat cgcattatcc gtagtcatcg
    26041 cgtctccctg accagattgt aaagcagtaa atgcttctgc atagttttct aattctaaaa
    26101 tttttgcatc tggtgcatgc tgtcggatat tcgcagccga tgtagaacct ttgactgcta
    26161 gaaccgttgt agaagcattc aaatcatcta cacttttgat ttggcttcct ttctttacca
    26221 acaaagcttg gccagcatcg aaatagacat ctgaaaagtc aacctgtttt tttcgttcat
    26281 ctgtgatcgt catcgttgca ataattgcat cgatatttcc gtttttcaat aatggaatcc
    26341 gagttttaga agtgacttca acaaattctg tttttccatt gtcaccaagg atctttttag
    26401 tgattgcttt tgcaatatct acatcaaatc cttgtacagt tctgctctca atatccatca
    26461 ttccaaataa tcgagtatca tacttgacac cccagatgat ttcattggta gatttgcttc
    26521 gctctaaaat atcttcattt gccaacccat ttcctttaca tccggctagt gcaagaaaag
    26581 caatgcctaa aaggaaaatc aggcgtattt tttttaacct gcgcatcttt ttcctcctat
    26641 caatgattga taactttact gataaattgc tgtgctcgga cttcatttgg attttcgaaa
    26701 aagtctctca catttctgct gtcttccaat acttctccat cagccatgaa gataacacga
    26761 tccgccactt ctttggcaaa gcccatttca tgtgtcacga caatcattga cataccgtca
    26821 tgagccaatt ttttcataac gtctaataca tcaccaatca tttccggatc caaagcagaa
    26881 gtaggttcat caaacagcag catctcagga ttcatcgcta aacctctggc gattgccacc
    26941 cgttgctgtt gtcccccgga taacatggaa ggataagaat ctttcttatc taacatattg
    27001 acagttttca aaaatttctc cgcgtttttg actgcagttg cctggtcttg cttcaacact
    27061 ttgattggtg ctaatttgat gttttccaga acagttttat ttgggtacaa attgaaatgt
    27121 tggaaaacca tgccgatgtt ttttcggact tctgtcagtt ttgtcttttt atcatgcaag
    27181 tcagtatcat taatcagcag cttacctgaa gagatcgtct ctaatccatt gatacagcga
    27241 agcatcgtgc tctttcctga accagaagga ccaatgacaa cgacaacttc tcctttctcg
    27301 aattcgagat tgatattttt taatgcgtgg aacttgccat aatatttatc cacgtgatca
    27361 aatttaatca ttgccataga attacactcc cattattatt tagtaagatt tcttt
//
LOCUS       DAFLWC010000033        26541 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.034, whole genome shotgun sequence.
ACCESSION   DAFLWC010000033 DAFLWC010000000
VERSION     DAFLWC010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26541
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.034"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..1152
                     /locus_tag="L1V17_001299"
     CDS             <1..1152
                     /locus_tag="L1V17_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HBN1236078.1"
                     /translation="PSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSA
                     EAPKEKVETSGSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKED
                     IENFLAGGPSSAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPT
                     RKAIAKAMVNSKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALT
                     ATVKKYPVLNASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEI
                     NEKAKLAHDGKLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIV
                     NAEGEIVVGRVMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            1160..2566
                     /gene="lpdA"
                     /locus_tag="L1V17_001300"
     CDS             1160..2566
                     /gene="lpdA"
                     /locus_tag="L1V17_001300"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBN1236079.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            2728..3003
                     /locus_tag="L1V17_001301"
     CDS             2728..3003
                     /locus_tag="L1V17_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HBN1236080.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            3009..3776
                     /locus_tag="L1V17_001302"
     CDS             3009..3776
                     /locus_tag="L1V17_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HBN1236081.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            3944..5773
                     /gene="typA"
                     /locus_tag="L1V17_001303"
     CDS             3944..5773
                     /gene="typA"
                     /locus_tag="L1V17_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBN1236082.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            6034..7806
                     /gene="recQ"
                     /locus_tag="L1V17_001304"
     CDS             6034..7806
                     /gene="recQ"
                     /locus_tag="L1V17_001304"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HBN1236083.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            7920..8222
                     /locus_tag="L1V17_001305"
     CDS             7920..8222
                     /locus_tag="L1V17_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HBN1236084.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            8225..9388
                     /locus_tag="L1V17_001306"
     CDS             8225..9388
                     /locus_tag="L1V17_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBN1236085.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            9414..12842
                     /locus_tag="L1V17_001307"
     CDS             9414..12842
                     /locus_tag="L1V17_001307"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBN1236086.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            12863..13987
                     /locus_tag="L1V17_001308"
     CDS             12863..13987
                     /locus_tag="L1V17_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236087.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            13977..14414
                     /locus_tag="L1V17_001309"
     CDS             13977..14414
                     /locus_tag="L1V17_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBN1236088.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            14398..14736
                     /locus_tag="L1V17_001310"
     CDS             14398..14736
                     /locus_tag="L1V17_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HBN1236089.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            14855..15415
                     /gene="rsmD"
                     /locus_tag="L1V17_001311"
     CDS             14855..15415
                     /gene="rsmD"
                     /locus_tag="L1V17_001311"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBN1236090.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            15412..15903
                     /gene="coaD"
                     /locus_tag="L1V17_001312"
     CDS             15412..15903
                     /gene="coaD"
                     /locus_tag="L1V17_001312"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBN1236091.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            15893..16936
                     /locus_tag="L1V17_001313"
     CDS             15893..16936
                     /locus_tag="L1V17_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HBN1236092.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            17095..17823
                     /locus_tag="L1V17_001314"
     CDS             17095..17823
                     /locus_tag="L1V17_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HBN1236093.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            17939..18184
                     /locus_tag="L1V17_001315"
     CDS             17939..18184
                     /locus_tag="L1V17_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBN1236094.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            18181..18399
                     /locus_tag="L1V17_001316"
     CDS             18181..18399
                     /locus_tag="L1V17_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HBN1236095.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            18535..19074
                     /locus_tag="L1V17_001317"
     CDS             18535..19074
                     /locus_tag="L1V17_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HBN1236096.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            19067..21340
                     /locus_tag="L1V17_001318"
     CDS             19067..21340
                     /locus_tag="L1V17_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HBN1236097.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            21378..22424
                     /gene="holA"
                     /locus_tag="L1V17_001319"
     CDS             21378..22424
                     /gene="holA"
                     /locus_tag="L1V17_001319"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBN1236098.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(22513..22767)
                     /locus_tag="L1V17_001320"
     CDS             complement(22513..22767)
                     /locus_tag="L1V17_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBN1236099.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(23167..23436)
                     /locus_tag="L1V17_001321"
     CDS             complement(23167..23436)
                     /locus_tag="L1V17_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236100.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(23906..24361)
                     /locus_tag="L1V17_001322"
     CDS             complement(23906..24361)
                     /locus_tag="L1V17_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HBN1236101.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(24499..26427)
                     /locus_tag="L1V17_001323"
     CDS             complement(24499..26427)
                     /locus_tag="L1V17_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBN1236102.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQIIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
BASE COUNT         8830 a         4606 c         5611 g         7494 t
ORIGIN      
        1 ccgtcacctg tcacagggac agttaaaaac gtgattgttc cagaaggcac tgtagcaaat
       61 gttggggatg tattagtaga aatcgatgct cctggacaca atagtgcacc gtcaactagt
      121 gcgccatcag ctgaagcacc aaaagaaaaa gtggaaacat caggttcagc aagtgtcgtt
      181 gaagctgccg atccaaataa acgtgtattg gctatgccat ctgttcgtca atttgcccgt
      241 gaaaaagatg tagatatctc acaagtaact gcaactggaa aaggtggcag agtaacaaaa
      301 gaggacatcg aaaacttctt ggcaggtggt ccaagcagtg caccagcgaa atcagaagcg
      361 ccagaagcgg cagcaccgaa agaagcagct cctgcagcag aaagcaaacc agctgcacca
      421 gcaaaaccat tcaagtccaa cttaggagac ttggaagaac gtgtagcaat gacgccaaca
      481 cgtaaagcta tcgctaaagc aatggtcaac agtaagcata cagctccaca cgtgacattg
      541 catgatgaag tagaagtgtc taaactatgg gataatcgga aacgatttaa agaagttgct
      601 gctgcaaatg gtacgaaact tactttcttg ccatatgtcg tgaaagcttt aacagcgact
      661 gttaagaaat acccagtatt gaatgcatct atcgacgatg caaaccaaga aatcgtttat
      721 aaacattact acaatatcgg tattgcaact gatacggatc acggactata tgtaccaaat
      781 gtgaaagatg cagaccgcaa aggaatgttt gctattgcag acgaaatcaa tgagaaagca
      841 aaattagctc atgacggcaa actatctgca gaagatatgc gcaatggaac aattacgatc
      901 agcaatatcg gatctgtagg tggcggttgg tttacaccag tcatcaacta tccagaagta
      961 gctattttag gtgtaggaac gattgcacaa caaccaatcg taaatgctga aggcgaaatc
     1021 gttgtcggtc gtgtgatgaa actgtcatta agtttcgatc accgtatcgt agatggagca
     1081 actgcgcaac aagcaatgaa taatatcaaa cgtcttttag ctgatccaga gctattaatg
     1141 atggaaggat gataaacaaa tggtagttgg agattttgct gtagaattag atacagttgt
     1201 aattggtgcg ggacctggtg gctatgtagc tgccatccgc gctgctgaaa tgggacaaaa
     1261 agtagcaatc attgaaagag agtatattgg cggtgtttgt ttgaatgtcg gctgtattcc
     1321 ttcaaaagca ctgatagctg caggacacca ttatcaagag tcactagatt ctgaaatgtt
     1381 tggagtaact agtgaaaacg tcaaactaga ttttgcaaaa acacaagaat ggaaagaaaa
     1441 caaagttgtc catacgttga cttctggtgt tggtttccta ttaaaaaaac ataaggttga
     1501 aacaatcgaa ggagaagcgt tcttcgtaga tgatcacaca ctacgcgtca ttcatccaga
     1561 ttcagctcaa acttattcgt tcaataacgc aatcatcgca acaggttccc gtccaatcga
     1621 gattccagga tttaaattcg gaggacgtgt gttagattct actggcggat tagcattgaa
     1681 agaagtacct aagaaatttg tgatcatcgg tggcggtgtg attggtgccg aattgggcgg
     1741 agcgtacgca aacttaggag cagaagtaac gattcttgaa ggctcaccac aaattttacc
     1801 aacttacgaa aaagatctag taaaattagt agaagatgat ttcaagaaaa aaggcgtaac
     1861 agtcgtaacg aatgcaatgg cgaaagaagc agtcgataac ggtgacagcg tgacagtgaa
     1921 atatgcagtg gacgggaaag aagaatccgt tactgctgat tatgtgatgg tcactgtagg
     1981 tcgtcgtccg aatacagatg atatgggctt agaacaagcg ggtgtcgaag taggagaacg
     2041 aggattgatc acggtggata aacaaggacg tacgaacgta cctaacatct atgccatcgg
     2101 tgatatcgtt ccaggggcgg cattagcaca caaagccagt tatgaagcaa aaatcgctgc
     2161 tgaagcaatc tctggcaaaa aagtagctgt agattataaa gcaatgccgg cagtagcctt
     2221 cactgatcct gaattggctt ctgtaggtat gacgatcaaa gaagcaaaag atgctggtat
     2281 cgaagcaaaa gcatataaat tcccattttc agggaacggt cgggcattat cgcttggtaa
     2341 aacagaagga ttcatccgtc tagttacgac gatcgaagat aacgtgctta ttggcgcgca
     2401 aatcggtgga gtcggcgcaa gtgatatggt ctctgaatta gctttagcaa tcgaatcagg
     2461 aatgaatgct gaagatatcg ccttgacgat tcatcctcat ccatctcttg gcgaaatcgt
     2521 catggatgct tcggaattag cattaggttt accaatccat atttgatttg aataatacag
     2581 gcgaaacgca actgaaaaat cagttgcgtt ttgtttttta gaattatcaa taatattatt
     2641 atgtaaactt aaaaatatga caacttcttg gtttattacc acttcctatg ctacactgaa
     2701 gaggaatatg aaataggaga gttgaagatg caagaatatc agtatccact tgatttagat
     2761 tggacaacag acgaaatggt cattgtaatg aagatgtggg aagatctgga acgtgcgaat
     2821 gaaaaaggga taaacaatga agcttttttg aagacttatc agcagtttaa aactgttgtc
     2881 aaatccattg gtgaggaaaa acgattggga cgggaatttg aaaaagcttc cggttattct
     2941 ttatatcgta cagtgcagca agcaaaaaaa aatccaaaca aaactttgag aatgaacggg
     3001 tgagataaat ggaacagatg attgatcata tcaagtcctg gcttgaagaa gctggtgaga
     3061 aaatcaaatc ttctcaacaa acattaacaa tctcgcaaaa atcaaatcga acggatctag
     3121 taacaaatgt cgatcgaaac atccagaatt ttctaatcga aaaaatccat tcctttgatc
     3181 cagaggcgaa aatattggca gaagaagaag ggtgtaatca attatcggat ctcgatggaa
     3241 gagtctttat catcgatcct attgatggca ccttgaattt tgtgattgaa ggggaaaatt
     3301 tttgtattat gctcgctgtt tatgaatccg gcgttggaaa gcttggtttc atttatgacg
     3361 tgatgagaaa tgaacttttt tggggtggaa aaggaatagg cgtgtataaa aatgatgagc
     3421 cattgcctag accagcaaat aaatccttat cggaaggctt acttggtgtg aatagttatc
     3481 ttttcggtca taataaatat ggaatccgag aaattgcgga aagcagcatg gggacacgta
     3541 tgtacggatg cgctggtctt gaactagtgg caatcttgaa aggaaaccac attgcttata
     3601 tttcaaacct tagcccttgg gattatgcag cgggaaatgt cttattggaa gagtttggta
     3661 tggtaacaag cggtcttttt ggtactcctt tgacatttga aaaaagggaa tactatttag
     3721 cagggacttc ttgtgcatat gcagaaatcg cagacctttt gaaaaaagaa ggctgaaaaa
     3781 aaggtagaaa tcattcacaa aaatgataaa aacgagcaaa agattaattt tctcgaaaaa
     3841 atgaaaacat tttactatat ttcatgaaaa aagtctgcta taattagcag tcgagtaaaa
     3901 tttgccctgt cataaagaac caataaaaaa ggagttagtt acattgaatt atagaaacga
     3961 tatccgtaac gtcgcaatta ttgcccacgt tgaccacgga aaaacaacat tagttgatga
     4021 actattaaaa caatcagata cattagacgc acatacgcaa ttgcaagaac gtgcgatgga
     4081 ctcaaatgcg ctagaaaaag aacgtggtat cacgatttta gccaaaaaca cagctgtaga
     4141 ctataaaggt attcgcgtaa acatcatgga tactccagga cacgcggact tcggtggcga
     4201 agtagaacgg atcatgaaaa tggttgacgg cgttgtgttg gtcgtagatg cgtatgaagg
     4261 aacaatgcct caaacacgtt ttgtattgaa aaaagcactg gaacaacata tcacaccaat
     4321 cgttgtcgta aacaagattg acaaaccttc tgctcgtcct gagcatgtcg tagatgaagt
     4381 tcttgaacta ttcatcgaat taggagcaga tgatgatcag ttagactttc ctgtgattta
     4441 tgcatctgca ctaaatggta cgtcaagctt gtcagatgat ccagcagatc aagaaccaac
     4501 catggcacct atttttgata caattattga aaaaatccct gctcctgtcg ataacagcga
     4561 cgaaccatta caattccaag tttcattact tgactacaac gattatgtag gtcgtatcgg
     4621 aatcggacgt gtatttagag gaacaatcaa agtaggagac caagtagcat taattaaatt
     4681 agacggaaca gttaagaaat tccgtgtaac gaaattattt ggtttctttg gactaaaacg
     4741 tctagagatt caagaagcaa aagctggaga cttgattgct gtctcaggta tggaagatat
     4801 ctttgtcggt gaaacagtta ctcctgtgga tcatcaagat gcgttaccta tccttcacat
     4861 tgacgaacca acattgcaaa tgactttctt agttaataat tcaccatttg ccggtcgaga
     4921 aggtaaattc gtaaccgctc gtaagattga agaacgtttg atggcagaac ttcaaacaga
     4981 tgtatcctta cgagttgaac caacaaactc tccagatgca tggacagttt ctggtcgtgg
     5041 agaattgcat ttgtctatct tgattgaaaa catgcgccgt gagggatacg aattgcaagt
     5101 atctcgtcca gaagttattg aaaaagaaat cgacggtgta aaatgcgaac cgtttgaacg
     5161 cgtgcaaatc gatacaccag aagaatatat gggtagtgtt atcgagtcct tgagcttacg
     5221 taaaggtgaa atgcaagata tggtccatac aggaaacgga caaatccgtt tgacattctt
     5281 aacacctgcc cgcggtttga ttggttattc aactgaattc ctttcaatga cacgtggtta
     5341 cggaatcatg aaccatactt ttgaccaata tctgccaatg cttcctggtc aaattggcgg
     5401 acgtcaccaa ggggcgcttg tttcgatcga tacaggaaaa gcaacgactt attctatcat
     5461 gagtatcgaa gaacgcggta cagtcttcgt agaaccaggt acagaagtat atgaaggaat
     5521 gattatcggg gaaaacagcc gtgataatga tttgactgtc aacatcacga aagcaaaaca
     5581 aatgacaaac gtacggtctg ctactaaaga ccaaacatct gtcatcaaaa aaccaaaaca
     5641 attgacgttg gaagaatctt tggaattctt gaatgatgat gaatattgcg aagtaacacc
     5701 agaaagcatt cgcttgagaa aacaaatttt agagaaaaat gctcgtgaaa aagcatctaa
     5761 aaagaaaaaa taatctgtaa aaggatgaag agagaaacca gcttgttata aaaaatagct
     5821 ggtttctttt tttgtccaac tcttttctgt ggagaagtca tctttgtcaa tggacataaa
     5881 ttcagaaaat acgccgaaag acgtttaaaa gacttttaaa aaacttattt ctagagagtt
     5941 tttgtttcat aataagataa tgtttcacga aaggagatca acttgtcctt cgaagaaaat
     6001 cgaagtaaaa tggcaagaga aaggagcggg aagatgaacg acttattaaa acaatacttt
     6061 ggctatgatg agtttagacc tggtcaaaaa gaaattatcc agaaagtcat tgatcaggaa
     6121 aatgtattag gaatcatgcc taccggaagt gggaaatcaa tctgttacca gcttccagct
     6181 ttactattag atgggcttac tgtggttgtg tcccctttaa tctctttgat gaaggatcag
     6241 gtggacgcgg cgaatcaatt aggtataccc gccactttta tcaatagctc gttagatggt
     6301 tacgaaacag ctagacgctt ccaagaaatc gatagacagc agtaccgttt actttatatc
     6361 gctcctgaac gttttatcat gccggatttt atccaagcaa tgaagcgatg gaacgtccgt
     6421 atgatcgcta ttgacgaggc acattgtatc tctcagtggg ggcatgattt ccgcccaagt
     6481 tatttacaga tggcgaacca gctagatcaa ctgccaaatc gtcctgtaat tgttgctttg
     6541 acagctacag cgactgtgca agtagctgct gacataaaaa gacttttaaa aattccagaa
     6601 aacaaccata ttcagactgg ttttgaacga gaaaatctac gatttcaagt aattaaagat
     6661 caaaaaaaag aacaatatct aatcgaatat ttaaagatca acaaaaatca atctggtatc
     6721 atttatgcag caacgagaaa agaagtagac cgtctctatc atttgcttaa aaaattcgat
     6781 ttttccgtgg gtagatatca tggtggtcta aatgagaatg agcgaacaga aatgcaagaa
     6841 gcctttttat acgatcgctt gcagctgatt gtagcgacaa atgcatttgg tatgggtata
     6901 aataaaagca atgtccgttt tgttatccat tatcaaattc ctggctctct agaagcatac
     6961 tatcaggaag ctggtcgggc gggaagagat ggtctttcca gtgaagccat cctgcttttc
     7021 tctcctcaag atatccaagt ccaaaagttt tttatccagc agtcccaaag agaagaaggg
     7081 caaaagcaaa aagaatatga aaaattaaaa gcgatgacag aatacgtgta tattgagtcc
     7141 tgtcttcagc aatacatcct aaactatttt ggcgagacaa gcagtccgtg caaccgttgt
     7201 ggtaactgtt tagatgacag agaaatagta gaagtaacga cagaagcaca gatggttctt
     7261 tcttgcttaa aacgtatggg tgagaactat ggtaaacaaa tgctgatgaa agtcttagca
     7321 ggatcgaaag aacaaaagct gcaagcttta ggttttggac atttatctac ctatggactg
     7381 atgaaaaacc aatcgcaaaa agaaacgatg cagttaattg aatatttgat atcgaatggc
     7441 tatcttctga ccatcaatgg tgagtatcct gttttgaaag taacagaaag agggatacaa
     7501 gtattgaaag gacaagaatc tgtttatcga aaggaaccca agaaagtcca gcagctatcg
     7561 gatgaagaaa ccgatacact atttgaagtg ctgcgggaac tgcgaacgga tctagcatca
     7621 gaagcaggcg ttcccccgta tgtcgtattt tcagattcca cattgaaaga aatgagccga
     7681 atacgtccat caagcagatt ggagatgctt cagataaaag gagttggcca aagcaagctt
     7741 gataaatatg gcgaagcctt tttatctcgg ataaaaaatg cggactctaa cgttctggat
     7801 aagtagaaag aacgaatacg taaaaatgaa taaaaacaac tggttaaatc tgtttttttt
     7861 gctccttatg aaaatcaaat atgttataat taaggaatta gaatgggagg taagcacaga
     7921 tggattcttt gtcgaaaaaa cttgcgatcc aagtattaaa tgatgaagca gaacggatca
     7981 aacgattaat ccgaaatcaa aacaacagtc tctgtatctc acaatgcaaa gccttcgaag
     8041 aagtggtaga tacacagatg tacggctttt cccggcaagt cggttttgct gtccgtatag
     8101 gagtaatcgg aaagaacgag ggccagctga tgttaagtga gctagaacga gaattgaatc
     8161 agttatatag tgaggtttac caagaaattt atgataaaaa agaagttggc aaggaggaat
     8221 agacttgcct aagaaagtga aaaaaaggca tctattagac tatagcatct tgattcccta
     8281 tttaatttta tgtgtattgg gattgatcat ggtatatagt tctacgtcgt atctattatt
     8341 agaaaacgga caaaatccgt ccgcatcagt cattaaccag agtatttttt gggtgcttag
     8401 cttgattgct atcgcactac tttataaaat gaaaacagat gttttgaaaa accagcgttt
     8461 gatcatggca gccatcgcag ttttgacgat tttgctgctg attgttgtgt tttttggtaa
     8521 ggagatcaat ggggcgaaag gttggctgca aattgcagga ttctcgatcc aacctgccga
     8581 atacctaaaa atcatttcta tctggtacct gtctctgact ttatctaaaa gacaaaacag
     8641 tgtacaaaaa gattttcttg ggactgtgaa acgtccactt gcaatggtta tcggacttac
     8701 tgcattagtc gctattcttc ccgattttgg taatgcggca gttatctttt tgattatttt
     8761 ggttctgctt ttagccagcg gagtcaatta tgtgtatact ttgattgtag gagtaggagg
     8821 cttttgtcta agtactttta cgatctggct gatcaatatc acaaacggaa agatcttacc
     8881 cggacgttta cagtatatct ataatcgatt tgctatttac caaaatcctt tctcagacga
     8941 attaaataaa gggcatcaac tagtcaacgg ctactatgcc atgttcaacg gaggactatt
     9001 tggcagggga ttaggtaaca gtatccagaa aaaaggattt ttacaagaag cacaaaccga
     9061 ttttatttat gcaatcgtag tggaagaact gggagtgatt atggggattt tgatattagc
     9121 gttgctattc tttatgattg tgcgcattgt ccttgtaggt atccgttcaa aagatccgtt
     9181 caattcgctt ttgtgcattg ggatcggcgc aatgtttttg atccaagtat ttgtcaatct
     9241 tggaggaatt actggcgtta ttcctttgac agggatcacg ttcccatttt taagtcaagg
     9301 aggctccagt ttgctgatgc tttcgatttg tgtcggcttt gtcctcaaca tcagtgcgga
     9361 tgaaaaacgc aagagcttag gtttataata aaaaaagatg taggagtggt tcgatgaaaa
     9421 aagttttagt tgctaacagg ggtgaaatcg ctgtacgtgt atttcgtgct tgtacagaat
     9481 taggaattaa aactgttgga atctatgcag aagaagatga atattccgta caccgtttca
     9541 aagcggatga agcatattta gtaggacaag gaaaaaaacc gattgatgcg tatctagata
     9601 ttgaagggat catttctatc gcgaaagaat gcggagctga cgctattcat ccgggttacg
     9661 gtcttttgtc ggaaaacttg aattttgcgc aacggtgcga agaagaaggc atcatttttg
     9721 ttggacccaa actgcatcat ttagatattt ttggagataa aatcaaagca aaagctgcag
     9781 ctatcgaagc ggggattgct tcgattccag gcacagatgg accaatcgct tctatagacg
     9841 atgccttgga gtttgcgaaa caatacggtt atccgattat gatcaaggca gctctaggcg
     9901 gcggcggacg cggcatgcgt gtagctcacg atgaaaagag tgcaagagag ggctacgaac
     9961 gtgcgaaaag cgaagcaaaa gcagcctttg gtagtgatga agtgtatgtt gaaaaataca
    10021 tcgctaatcc taagcatatc gaagtacaga ttctcgggga tacgcatgga aacgtcatcc
    10081 atctttttga aagagattgt tctgttcagc gccgtcacca aaaagtagta gaagtagcgc
    10141 cttgtgtctc tatgaatgaa cagcaacgtc aaaaaatctg ccaggcagct gtccaattga
    10201 tgaaatatgt cgggtatgtc aacgcaggta cagtagaatt tcttgttgaa ggagatgatt
    10261 tttactttat cgaagtcaac cctcgcgtcc aagtggaaca tacgatcaca gaaatgatta
    10321 cagatattga tatcgtaaca acgcaactgt tgattgctca aggtttggat ctgcataaag
    10381 aaatcggatt gcctcagcaa gaaggaatta aattaaatgg ttcagccatt caatgccgaa
    10441 tcactacaga agacccgttg aataactttt taccagacac agggaaaatc gatacgtatc
    10501 gttcacctgg tggttttggc gtacgtctgg atgtcggaaa tgcttacgcg ggctatgtag
    10561 tgacaccgta ttttgattca ttgctagtaa aagtatgtac gcatggtgct acctttgaaa
    10621 cagccattca gaaaatggaa cgttgcttga aagaatttag aatccgtgga gtgaaaacaa
    10681 acattccatt tatgctcaat gtcatcacac atcctgaatt ccaatcagga aatgcaaaaa
    10741 caaccttcat tgatagtaca gcaacattat ttgaatttcc tcgactacga gaccgcggaa
    10801 acaaaacgat gaaatatatc ggtgaaatta ctgtgaatgg ttttccaggt atcgaaagtg
    10861 gcgaaaaacc attttatgaa gaaccacgta tgcctaaaga tctaatcaca agaactgatt
    10921 acgtaacggc taagaatgta ttagatgcga agggtgccga tgctttggtc gaatggatca
    10981 aaggacagga aaatttgttg ttgacggata cgacatttag agacgcccat caaagtctgc
    11041 tagcaactcg tgttcggaca aaggatttca agcagattgc acgtttgact ggagaaggtc
    11101 ttcctgaact cttttcaagt gagatgtggg ggggagcaac atttgatgtg gcttaccgct
    11161 ttttgaatga agatccttgg caacggttga gaaaaattcg ttctttaatg cctaatacgt
    11221 tgctgcaaat gcttttcaga ggttcaaatg ccgttgggta ttctaattat cctgacaatg
    11281 tattggtgga atttgtcaaa gaagcagcag cgcaaggaat cgatgtattt cgaatctttg
    11341 atagtttgaa ctggactcca caaatggaaa aaagtatcca agctgtacgg gatactggta
    11401 aaatcgcaga ggcagctatt tgctatactg gcgatatcaa cgatccaagt cgggcaaaat
    11461 acaatgttca gtattataaa gacatggcaa aggaactaga acaactgggt gcgcatatca
    11521 ttgcaatcaa agatatggct gggctgctta aaccgcaggc agcttatcgt ttgattagtg
    11581 aattgaaaga aacgacagat ctgccaatcc atctgcatac tcatgatacc agcgggaatg
    11641 gaatcatcac ttattctgct gcttcaaaag caggagtaga catcgttgac gtggcaatga
    11701 gtgcaatgag tgggaatact agtcagccta gcatgagcag cttgtattat gcactggtca
    11761 atggtccacg gctgccagaa atcacgattg aaaatgcaca gaaattaaac cattattggg
    11821 aagatgtgcg catgtattac aaaccgtttg aaaacggctt gaatgctcct gaaacagaag
    11881 tatatatgca tgaaatgcca ggaggacagt attcgaatct acagcaacag gcaaaagctg
    11941 tcggattagg tcatcgctgg gatgaaatca aacaaatgta tcatactgtc aacttgatgt
    12001 ttggcgatat cgttaaagta actccatcat ctaaagtagt tggagatatg gcactattta
    12061 tggtccaaaa tgatcttaca gaagaagata tttatgaaaa aggcgaaaca ctaagtttcc
    12121 ctgaatctgt tgtgactttc ttccaaggag aactagggca acccgttggc ggatttccta
    12181 aaaaattgca aaagattatt cttaaaggca gacctgcatt gaatgaacgt ccaggtcttt
    12241 tggctgaatc agtcgacttc aacgaagtaa aaaaagaatt ggcagaaaaa attggctatg
    12301 aaccaaaaca agacgaagta ttaagctatt tgatgtatcc gcaagtcttt ttggactatc
    12361 aaaaagcata taatcaattt ggcgatgtta cattactgga cacaccaaca tttttccaag
    12421 gtatacgttt gggtgaaaca atcaatgtac aaatcgaacg cggaaaaacg cttatcattc
    12481 gtttagatga aatcggagaa cccgatatcg aagggaatcg cgtactgttc ttcaatttga
    12541 atggacaaag acgtgaaatc actatcaaag ataattcgat catcagtacg gtccaaaccc
    12601 gattgaaagc tgaaccgaca aaccgagaac aaattggagc aacgatgtct ggttctgttt
    12661 tggatgtatt agtgaaaaaa ggcgataacg ttaaaaaagg tgatacgttg atgattactg
    12721 aagcgatgaa aatggaaacg gccatcgaag cacgttttga cggagaagtc gcacatgtat
    12781 atgtgtcttc aggagacact atttcgtctg gtgacctttt gattgaagtg actgagaaat
    12841 aataagcgaa aggtggggaa acatgaaaag actgggtttg ttttggctga ttctgctatt
    12901 agttattgtg gcattctaca tggaaccagt cttgtttccg ccaaaacttg aagtgaagga
    12961 aaactctgat caacaaatat caaaccaaat gacaacgtgg aaataccagg agcttaaagc
    13021 aactggtttt tctacttata tcggaaaacc gatcgatcag ctggaaaagg attttggcca
    13081 agcctatgat cgattaacta gcggatttgg ttttgaaaca agatattatg aaaataaagc
    13141 tagtcatctc acatttgaag cgaacatcca agacagcaga gtcacaactg ttaaagtact
    13201 gcaaacaggg cctgctgata tcgcgccgtt ttatttaggg atgacgatgc aagatcttac
    13261 gaaaatcact actatctata ctaatttcac ttttgagtac catgatacag aagttggaat
    13321 cgaactaatg gaagaggata tgaattatcg tccgctaatt gcttttgata acgacacttt
    13381 tgctatttta ttttttgatc aaacaacaaa cggcctattt tcagttgtgt atttagataa
    13441 agatagtctt ttgaaactat tgccatatca agtgtttggt gaaggccttc cacattatca
    13501 agcagataaa tcggctgatt gggaatcaat caatcgcgtt aaagaacgaa aaagtacgac
    13561 tttattaaat atgcttagaa gagaagacga acttcccata tacaatcaaa cacttgcctt
    13621 tcaaaaccac agtcagctgc tactacatga ttttttgaca aggcctgagg aaatattgtc
    13681 agaggaacgt atggctgatt ggcaaaaatc gctaggcagt gctcaaacga cagtgaaatt
    13741 ctcactgacg aatgatgaat tggagaagtt aatcagtaaa caaaaattag aaaatactag
    13801 tgggctattt attcatccgg cgattgacgc tactttttcg tttttatatt ggtacagcga
    13861 tccttacaac catgaccgtt tcatggaccc gggaacggat tctgtaggca ttgctttttc
    13921 taaagaaaat atgttagtct tattgcaaga agaaaacgga gaaagtagtg atagcagtga
    13981 tcgttaacga agagctgttt caactggagg atcaatgcct ccaagtcgct gaaatgataa
    14041 aaaagagtaa aacgatggct tcttatcttg aacataaaca gtcaatggaa gaatctgcaa
    14101 aagtttgcca gttgaaagaa gcgttcttgt ctaagaaaga agcatttgaa aatgtagcgg
    14161 catatggtga gtatgcacct gattatcgtg aaaaaaaacg agctgttcga aaagcaaaaa
    14221 gacagcttga tatggatgag catgttgcag ctttccgata tagtgaaaca cagctgcaaa
    14281 gtctgttgga tcaaattgtc caagtacttg ccgaagaagt ttctaatgaa atcaaagtag
    14341 atgcaggtag cccgtttttt gaaacgaaaa aacactttgg atgcggaggt aattgtcatg
    14401 caattagaca atagtgaatt tgaaataaca aaacgacgcg ggctgatcgt atgggtctac
    14461 agcttaaaac aattaaagaa tctgaaaaag ttcggcttgt tgcattatgt ctcaagaaga
    14521 atgaaatatg tcgtgcttta cttaaatgaa gagacattgg aagaaacaga agaacgaatc
    14581 cgtaaattac attttgttcg aaacgtagaa cgttcttacc gaccggatat cgaaatgaat
    14641 tttgccgaaa aaataggaaa caaaacagta ttaaaagacg aaggtttcga aattgaagag
    14701 ctaaatacag aaatccgatt agctgaacat ctttaaaaat ctcttatgag cagtttttaa
    14761 ataaaaaata acttggataa cgatcgattt ttgatcattg tccaagtatt tttttggtat
    14821 actagtacca gtaccatttc taaggagtga gtagatgcgg ataatatcag gaaattatgg
    14881 cgggcgccgt ttaaaaagtt tagcaggggc gaacaccaga ccaactacag ataaagtaaa
    14941 agaatccata ttcaatatga ttggaccata ttttgatgga gagacagtat tggatctgtt
    15001 tgcaggaagc ggtggtttag ctatcgaagc agtatctaga ggctgcagtc atgcggtatg
    15061 cgtagacaaa aattaccaag cgctaaaaat catcaaagaa aacatcgaaa ttacgaaaga
    15121 accagagaaa tttaccacaa taaaacttga tgcggacaaa gcaatcgaac ggctagcagc
    15181 ggagaaacaa caattcgact acttgtttct tgatccgcca tatgcaaaac aaaaaataat
    15241 cgatcaaatc cataaaatgg aagaactggg acttttttct aaaaccgcag ttatcgtatg
    15301 cgaaacggat aaaacagtcg aattgccaga aactgtggct ggattccatc aaataagaaa
    15361 acagatttat ggcataacgg ccgtaactat ctatagaaaa gagggaaatc aatgaaacgt
    15421 gcattattcc caggaagttt tgatcctttt acaaaaggtc acttagatac ggtggaacgt
    15481 gcggctaaat tattcgatga ggtagtaatt ggtgttttta tcaatacttc aaagaaaagt
    15541 ttgtttcccc cagaagaaag aatgacattg atcacaaaag ctgtttctca tcttcctaat
    15601 gtaaaagtca tgcatcaaga aaatcaattg acggtagaaa cagcaaaaga gattggtgca
    15661 gatgcgttga tcagaggcat acgaagtatc aaagactttg aatatgaacg agagattgct
    15721 cagatgaatc atcatctata tgatgaattg gaaactgtct tcttattagc aaaaccagaa
    15781 tatagtcacg tgagttccag tattttaaaa gaagtactgc actttggcgg agatgtgagc
    15841 agctacttac cgccagtgat caacgaagct ttagctggaa agcgtgaatc aaatgaaagc
    15901 taaacaatgg ttgaaaacag tactgattat catatttgga atgttgatca ttggatttgt
    15961 agtagttccc ttgccgtatt atgtagaatc accgggagcc acgatcgatc tgaaagaact
    16021 aattacggtc aatgataagg aagataaagg ttctgggtct ttctctctta cctctgttgg
    16081 tatcaggcaa gctacaggtt tcttagcttt aaaagctaaa atgacccctt ttgaagaatt
    16141 gatcagtgaa gaagaattga ctggtggggc gacaaatgaa gaatataatc aaatgcaaca
    16201 gtattatatg gattcttccc aaaatgcagc aatcgaacaa gcgttaaaac ttgcagacaa
    16261 gccttataaa atggaattca aaggcgtata tgtcatgagt gtagagaaaa catcgaattt
    16321 ctttggcaag ctttcagttg gagatacagt aacaaaagta gacgggaaaa gctttcaaag
    16381 tacagaagca tttatggatt atgtaaaaag ccaaaaagtt ggacaaacaa tcgaaatcag
    16441 ttatttgcat aatggtgaag aaaaaacagc ttctggtgat ctgatcgagt taccaacaga
    16501 taaaaaggca ggaataggta tcacgcttac tgaccatacc gagatcgaat cagatacaga
    16561 tgttcgtatt aattctggct ctatcggtgg gccatcagcg ggattgatgt tcactttaga
    16621 aatctatgaa caagtcactg gtaaaaactt gcgacatggt aagcaaattg caggaactgg
    16681 aacgatcaac agtgaaggag aagttggccg aatcggagga atcgataaaa aagtggcaag
    16741 tgcggataaa gctggcgtag agattttctt tgcaccagat gatacgattt cagacgatgt
    16801 taagaaagaa tatcctgaaa taaaaaccaa ctacgaagaa gcaaaagctg ccgctaaaaa
    16861 attgaattcc tcaatgaaaa tcgtaccagt aaaaacagta caagaagcgc ttgactatct
    16921 agagaaaatg aaatgaaact aaataattaa agaggggttg tgacacgagt tctgtcacaa
    16981 cccctctttt tcgtcaaaaa tcttcacgat aaaaataaaa acaaaagaaa aaattgacgt
    17041 aattagatgt tgaagggacg attttgccag agctcactgt ttcttcaatt ttaaatgaaa
    17101 ggagtaatga atgattttta ctggtcattc tttgaaaaaa gaacaatgat agaaaaaatc
    17161 agcaagaaaa tactagcttc acccaaattg atcatttgga tgtctatgat agttcttatc
    17221 ttttgtatcg caagtggttt tttattatca aatttgctat tttatagaga aacagaagag
    17281 actgctgcaa aagaaatact ttcttcgttt agttccagtg gagaagatcc atcagctgaa
    17341 ggaaacgatg tagaagagga tgctcgtcca aaggtcatgt acaccgatat caaaggaagt
    17401 gtgaaggagc ctggtatcta ttccttttct tcagaagaac gggtctatga tgtactaaag
    17461 cgtgcaggtg gattattaga agaagcggat agcgatcgaa tcaacttttc tgcgaagata
    17521 gaagatcagc aagtcctata tatccctgct gtaggtgaag agctgccaga acatcttgat
    17581 cagttggcat cctcggaagg aaaacagcct acagcagatt ccgagcctcc caaaataaat
    17641 atcaatacag ccactccatc agaacttcag cagattcctg ggatcggatc agtcaaagcg
    17701 caagaaatca ttcgatttag agaagaaaac ggatccttcc agaaagtgga agacctgcag
    17761 gagatttctg gtatcggtga aaagacagtt gaaaaactaa aaaacttcgt tacaattaaa
    17821 tagaatgatt caaaatcgac tggcacgagc aataaatgga cgctaatgga tactaagaat
    17881 aatccaattc taagagcttg gcaggacgag gaggtagtat ttttggatag gaaatagctt
    17941 gattgttcgc aaagaaacat taaaaaaacc aatgctgaat gtctatctcc aaaataaaat
    18001 atctgggatt catattatga atacggctgt cagcggcaat aacagtcaag ctctacgaga
    18061 acgctttgcc aaagatgtac ttagctatac agcagataaa gtatttattc tcattgggac
    18121 gaatgatcta gcagagcata aacaactttc taaagaaacg taccaaaaaa tctgcagtgg
    18181 atgatagttc agctgaaaaa agactatagt tctgatcatg ctttctttat cacgccacca
    18241 gcagtcgatg agacaaaaca aaaatatcgg aataacaagt tgatcaaaga atatatctct
    18301 gttctcacag aagtagcaaa acgccatgat tgtgaagtat cgatttttat acggaatttc
    18361 ttgaacaaat ggattcgaag aatttttata atgggctaat ggatgacgga cttcatttcg
    18421 gcagtgaagg gtaggatctt ttgtcagaca ggatgattcg ttatatttaa agaatatttt
    18481 gtttaagcaa tgagtacttt ttaatcaact tgaaaaaacg gaggaatata aaacatgtta
    18541 gaaaaatctt caaaagcatg cgatacgaat aaagaaaaag ttactgataa gtcacataat
    18601 gaacgcattc cttgggacca gtactttatg gctcaggcag tactgttatc tttacgtagt
    18661 acgtgtacac gtttagaagt aggagcgaca ctcgttcgag aaaaaaggat cattgctggc
    18721 ggctataatg gagcagtcag tggagatgtc cactgcatag atgaagggtg ttacgtcgtg
    18781 gatggacact gcttgcgaac gatccatgca gagatgaatg cactcctaca gtgtgcaaaa
    18841 cttggtatcc cgacggaagg ttcagaaatc tatgtcacac attttccatg tttggcctgt
    18901 acaaaggctt tgttgcaagc tggtgtgaaa gggatcaatt atctccatga ctatcgaaat
    18961 gatccttatg cccaagcgtt gatcgaacaa ttaggtgtat ctgtacacca agttgcttta
    19021 gactcacagc atttttcaaa acttcaaaat gaattaacag gaaaacatgt ctagcgtttt
    19081 agaaaggcat gttcgaaatc ggttgatttt tccggcaatt acgtcgatga ttatctgttt
    19141 gttgtattac actgacaatt ggggttatcg tttgcttctt gccggaattt ttttatggtt
    19201 ttcgctaaaa gaaggacgtt ttatcgcgta cttgtgtatt ttgtgtagca taacggtatc
    19261 catttcttat aggctacaag agtattcatt tttagaggaa aaaacaacat ctgcgcaaat
    19321 tactgtattt acagatacga ttcgtgcaaa tggtaatttt ttgacaatgg aaggaaggtt
    19381 atcagagaat aaacaaaagc tccagctttc ttatcaagta aacacagaag cagaattgaa
    19441 aacatggctt aacttccgag gaaagggaat agaattgact gctgaaggcg agttcatctc
    19501 tccagcaaaa aagcggaatc tttataattt tgaccaagaa gcttacttca ggaaccatag
    19561 aatttctgga cggttccaaa ttcaaaagat tgaacagatc accatgcaaa atcactggcg
    19621 aaactggctt cagagaaaaa gaggatcttt tatctccttt gtccaatctg aatttccgca
    19681 aaaaacaagt gtatatatta attctttatt atggggctat aaagatgcag gattcagaga
    19741 accagaagaa atttttaggg agagtggttt gctgcatctg ttcagtctat cgggtctaca
    19801 catccaattt tatttagggt ggctgtatta tttgtttcga cgtatcggat ggccactaca
    19861 cgtcagtatt attccgttga gtctactaac tatctgttat gtttctattg caggaagttc
    19921 tatttctgtt ttgcgtgcta gtttgctgtt tttattgcga ttgctagtca aattgctgaa
    19981 taagcattat tccaccatgg acttatttgc agttgtcttt tggcttcttt tactatttga
    20041 tcctcgattt ctttttcatg cgggtggaca gcttagtttt ttcatgagtt ttttgtttat
    20101 cctgatttct tttgatggag attggttgaa aaaaacggcc tctcacgtcc tgtttactat
    20161 gatcacgatg ccgttgattg tatggcattt ttatgagtgg cctattttag gtagtctttt
    20221 tacattactg attgcaccgg tattcaagtt tctttttctt cctggtgtgt tatttctcac
    20281 actcttcaat cgctggctgc cggaaacttt acttttgctg atagaagagg gattaatctt
    20341 atttgagcga ataatcgatt tttcttcagg gtcgtctctc attataggac gtttgcccct
    20401 tgtgctatct gggatgtata ttttcggatt actgatttgt atggataggt tgaaagaaca
    20461 acctgtgaaa cacttgtttt atgttggtct tttttctttt atttttttga ctttgccatt
    20521 tttacgcttt tcttcaacga tcgcttttat cgatgtcggt caaggagaca gtatcttttt
    20581 gcaaagtcct tttcgaaaag aaacgatttt gatcgatact ggaggtcagt tacactttga
    20641 aagagaaaag tgggcgcaag gtatgatacg tcctcctgct gaaagaaata tcgttccata
    20701 tctaaaaggt caggggataa gtgtaatcga taaactcatc ttgacacacg acgatacgga
    20761 tcatgtggga gaattaccca cgttatctca gcattttact atcaaaaaaa tttatatcgg
    20821 ttggggcgct ggacgaaatg agccattaca aaggcattta tctgaagctc aaaaaaatgg
    20881 tactgagatc attgaaatca aacatgggga caggatcagc ggttattatg atctttatgt
    20941 attgactcct tttgaaaagg gagagggaag aaatgaagat tcgattggtc tatggatgga
    21001 atataacaat aggcgctttt tatttttagg agatttgaat caagcaatgg aaaaacaatt
    21061 gcttttgatt tatcctaatc tgaaagccga tgtagtcaaa ttaggtcatc acggtagccg
    21121 tacgtcaagt aacacagatt ttctttccca tattgaagca aaacatggga ttatatcctg
    21181 cggcgtaaat aatcgttatg gtcacccgca cagcgaagta ttggagacac tagaagaaaa
    21241 tcagataaaa acatggcgaa cggatcaaca aggaatgatc acctatcgct ggcatccagt
    21301 ttttcatcct catgggctag tggaaacaat gatagactag taattctcat ctgctcatgg
    21361 taggataatt tttgaaagtg gtgagtaatt tgagtataca agcagagtta caaaaaatac
    21421 gtaaagaaaa acttgcatct tgttacttga ttttaggaac agaaaagttt ctccaagatc
    21481 aagttcggac agaaattgtc aaaaaaatcc aattagaggg cgaagatgac ttaaattttt
    21541 taagttttga catggaaaat gcaagtttag atgaggtagt agctgaagca gagacgttgc
    21601 cgtttttcgg agatcaacgg ttagtattcg tagagaatcc ttatttttta acaggtgaaa
    21661 aagtaaacaa tggaatcgaa caaaatactg atttattgac ggcttatttg aaagaaccat
    21721 tagaatcgac tgtattagta ttctttgcgc catatgaaaa gttggatgaa cggaaaaaag
    21781 taacgaaaca attgaaaaaa acagcaatta tcatcaatgt ccaacagttg aatgaaaaag
    21841 aagtacgtca atatctgatg aataccttag agaattcctc aatcaaaatg gaacgaagtg
    21901 caattgattt attcttgagg ttgaccgact tagatttatc caaaatgatg agagagttac
    21961 agaaattggt cctttatgga caaaatcaac agcaaatcac ggtaagagaa gtagaagaat
    22021 tagttcctaa aacgttagaa cataatattt ttgacatgac ccaatatatt ttaaaaggga
    22081 agacggaaca agctttgcgt ttatacgaag atttagttat gcaaggggaa gaaacaatca
    22141 aaattaatgc gattttgctt tctcaattac gtttattttt acagacaaaa tttcttgtaa
    22201 agattggtta tcagcaggca aatattgctg aaacattgaa aatccatcca tatcgtgtaa
    22261 aacttgccat gcaggaagta aaaaaattcg atgaacattt gctggtacag ttgtttgatc
    22321 aattagttga gatggattat caaatcaaaa cgggacaaat cgaaaaagaa ttaagttttc
    22381 aactattcgt tttgcgcaca gggcagttgt taagaaatcg ataagaagaa agacgagggc
    22441 aaagcatgcg ggaaggtcgt ttgtttttgt cctttttttg acaaataaaa aaatcggccg
    22501 aagccgattc ttttatttag cgattttttt gcttaaacga gatttgtcgc ggttagcttt
    22561 gtttttgtgg attagacctt ttgattcagc catatcaata gctttaacag cttctttata
    22621 taacgcatct acgttgtcag cacctgaagc tacagcatct tcaaattttt tgattgcagt
    22681 acgcatagcg cttgtttgag atgaattttt cacattagcg ttttcgcttg tacgaacacg
    22741 tttgattgca gattcaatgt ttggcattag tttcacctcc gataacttaa gttcttacgc
    22801 gtgttaccgc ataattcaac attcattatt atacctaaag gcagcgtgct ttgcaatatg
    22861 aacatgacaa gtttttttcc ttaacagtct tttattagga ttttttttca gtaaaaacgg
    22921 atagtacaag ctgaaaaaaa tcaaaaagac gctattgtgg gaggcaatag cgtcaaacca
    22981 aactagattt ttatttatct atttaaacaa agtttgaatg ggaatgtttg gtactaagtt
    23041 attatataac aaagagaacc gtttgcaaag ttttttttga aaagggatac gattccctgt
    23101 tgttctttgt ttttctatta agaaactgca gttattttat aaccagtatc ctttgatcag
    23161 taaaggctat tctggtgtac cgattatttt aatgtattca tcgatatttt ttatcaacat
    23221 tttttttatg accaactggt tccgacggtt ccatttgcca cttacttcca gcacatattt
    23281 atttaggggc aaacgtaaga tatattttgc caaatagcga tctttaagca ggccattgat
    23341 cacacggtcc tcaagctgca agttgatccc agtcagcatc attggctgtt cttgtaaaac
    23401 gtacgtatca attaaaagac cttcaaaagt ttccacaagc gtcttccttt cttttcaaag
    23461 taacctgaaa acaggcacta attcttccat tttgatattc gttgaagtgg atgcgatcat
    23521 tctttctttt gtccactgta atctagtata acaaaaaaga gcagaagagc caaaaagaaa
    23581 aaagagcatc gaattctata ggaagtctca ttggcacggc ctaaattatt acaaaacatt
    23641 gattaaaaaa agcccctgca tcgcaggagc atcccctata tcgttttaat aggtcaatca
    23701 aaaagcagta tcaaacacat tttgtatcaa atcaggaaat aatagataag ctaagcccag
    23761 aatcaaaagt accgctagaa gaaaccagcc gattgttcct atgaaatact ttaatttttc
    23821 gaacattgta tcacctcgtt gtcagtatat cacggatcag taaattgggg gtgttaagaa
    23881 tctcctaaaa tagacaaaat ttgttctatt ttcctaaagc aaatacttgt aagatacagt
    23941 aagtgatacc agaagcaatg accggtccgg cggcgattcc tcttaagaag acaacaccta
    24001 aaatcgtgcc gaaaacaagt gcaacagtga tttgtggatc agaagcaatc aatcctacac
    24061 ccttggaaga taagacagcc actagcccac cgcaaaaaac agctacccag ccaatagggg
    24121 atttaaaggc ttctaataga tcacgtagac cgatttctcc tgttgcgata gggattagaa
    24181 tagccgctgt gatgatcgtc accccaatat tgattccttt gccttgaagc caagggaaaa
    24241 aggaacggga ggctggtatg agcttcataa tcaaaacaaa agctgccgct atcatcagac
    24301 tttgattttt agctaaaatt gctacaagta aaataattcc taaaaaaagc caactttcca
    24361 tgaaatatat tcctcacttt cttcgaaaca atcataacat gtttttagaa agttacaaaa
    24421 gtaggaattc atccttcaag acctattcat aagctgtttt tttcataaaa taaacaaaat
    24481 cataaaaaaa cactttgctt atttgacaga agacagccgc gctttgtata gtggacaaga
    24541 cttacatttt tttgaagaat cagaaagatc aggtaaaggt cttagtaaac gcaagccatt
    24601 cagaataacc aatattgtgc ttccttcgtg tcctacaact ccaagaggta gatttaaaaa
    24661 ttgcaggaag ttagaagcaa tcaacaagag aataacaaga atcgaaaaaa taataatttg
    24721 tttgatgatc cgccgcattt ttaaagatag ccgatgactg tagacaaatt tatttaagtc
    24781 gcttttcatt aagacgatgt ctgcgatatc catagcggca tctgtccctt gccccatagc
    24841 gacacctaaa gaagcggctg ctaaagcagg cgcatcattg actccatcac caaccatcgc
    24901 atttacttgg taaagttcat tctctttttt gactagttgt gttttttctt ccggagtaca
    24961 gcttgcatag taatgttcaa tccctacttg ttcagcaatg gcctttgctg tgccagaatg
    25021 gtcgccggtt atcatacttg tatggatgtt ttgggattta aagtaggaaa ttacttgttg
    25081 ggtatttgct tttggaatat ctagcagacc taaaacagca attaactgct gatctttaga
    25141 aagataaatc acggttttgc cttgattttc caaacgttcg atcatttccg caatctcttt
    25201 gctgattatc atcgtctcag gatcatatgc gtgcttgcca actttccatt gcgcacctaa
    25261 ataggtagtt tgtaatccaa aaccagtaat ttcttctatt ggtaagtatt ggatttcttc
    25321 aggtattgtg caatcgaaat attgcaaaat cgcatgagca agtggatgcg tcgttttttg
    25381 ttccatagca acaagaagtt gttgtgccaa atccttttca tcaaagaaaa agctgtcagt
    25441 tacaactggt tttcctttag tgagcgttcc tgttttatca aaggcaatcg cttttaattc
    25501 agaaagcttt tctaaatgga taccgccttt gattaaaatc ccattttttg cagaatttga
    25561 aagagcagct agagaagctg gtgtagcaga tgcgacaagc gcacaaggag aagccacaac
    25621 taataatacc attcctcgat aaaagctttc atcccaactc caacctagga aaaagtgggg
    25681 gagaaggatc attagaggaa cagcaagcaa aatcaatttt acataattat tttcgattcg
    25741 ttcgataaat gaagctgttt gagttggcgt attctgcgct tcttctacta attggataat
    25801 cttagcaaag acagtttcgg aactcgtttt tgttactcga atcgtgatgg gatttccttg
    25861 attcagcgtt cctgcataca tctcatcgcc taaatatttt tctacaggca cagattcacc
    25921 gcttaatgca gactcatcga tcgttgcctg tgtgctttct aaaaagccat ctatcggaac
    25981 agctgctcct ttagcgacaa ataccaagtt atccaccttt agttgagaaa catctacttc
    26041 ttgcatttgt ccattttctt ttaataattg ggctttttgt ggttgaagat tcatcaaagc
    26101 agtaatttct ttttgacttt tattagttgt gtattcctct aatgcaccgc ttaaacaaaa
    26161 gatgaatgtc aacattgctc cttcaaagta attaccgatc aaacaggcac caatagcagc
    26221 taaagccatc aataaatcca cattcagtgt ccgatcattc cacaattctt tcaagccttc
    26281 cgatgtttgt ttatatccac cgatgataat ggcactgata taaaaaagtg gggtgatggt
    26341 aagagagaat cggtcgaaga taaaaccgaa gatcataaat aaaaggcagc cgattgttgc
    26401 tgcaaaagct tttttctgat tagtcatcgt tattagacct ccttgtcaaa acaaggatag
    26461 cataataaaa atgtaattga taataataac agctaaatga gaacgataat ggttatcatt
    26521 tggtgattaa gcttgatgtt g
//
LOCUS       DAFLWC010000034        26100 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.035, whole genome shotgun sequence.
ACCESSION   DAFLWC010000034 DAFLWC010000000
VERSION     DAFLWC010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26100
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.035"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..175)
                     /locus_tag="L1V17_001324"
     CDS             complement(<1..175)
                     /locus_tag="L1V17_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236103.1"
                     /translation="MLLLIGLILLIIGITKLSKANTIKKEAYELEQKNDEKLNKLHDR
                     ERFILSKEETLSDL"
     gene            complement(266..718)
                     /locus_tag="L1V17_001325"
     CDS             complement(266..718)
                     /locus_tag="L1V17_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBN1236104.1"
                     /translation="MHLNKYWILEEIEKLFVEFGSDAINPYKIIKYSDIDLIETDLGN
                     KTLGQTIHNKRCYVILINQNLSPSMKRFVLWHEIAHVRLHKGICTAAFRANNLSCMIY
                     GIEAEANMFAIEMLTRTIDEQDLSDMSQFQIIEYLGLPHNLEHLVLQH"
     gene            complement(731..1141)
                     /locus_tag="L1V17_001326"
     CDS             complement(731..1141)
                     /locus_tag="L1V17_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1236105.1"
                     /translation="MLLDRIKILLKERSMTLAELERKLNFGNGSMSRWNKSTPSGDKI
                     QKVADYFNVSTDYLLGRTDKRHYYDLTEKDKQDIALQAEKLLEGLNSDAETNYYGEPL
                     DDEDKEKLYDAIQLALALTKVKAKKKFTPKKYRQ"
     gene            1416..1628
                     /locus_tag="L1V17_001327"
     CDS             1416..1628
                     /locus_tag="L1V17_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1236106.1"
                     /translation="MTLKQQVLIALVKKGWSQRELARRMGISITYLRDIFIEKRKPKE
                     RLKQIEELLDIKLEVDSNDQPSEQEA"
     gene            1631..1843
                     /locus_tag="L1V17_001328"
     CDS             1631..1843
                     /locus_tag="L1V17_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236107.1"
                     /translation="MVQRLSKAEFKEKYKYSESTYQRRMKEFKKSRFSEGYNAVTSKE
                     ITIDVDLYEQFRTWRSKNRFRVRAVC"
     gene            1983..2138
                     /locus_tag="L1V17_001329"
     CDS             1983..2138
                     /locus_tag="L1V17_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236108.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGKKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(2135..2359)
                     /locus_tag="L1V17_001330"
     CDS             complement(2135..2359)
                     /locus_tag="L1V17_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBN1236109.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            2437..2625
                     /locus_tag="L1V17_001331"
     CDS             2437..2625
                     /locus_tag="L1V17_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236110.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            2951..3286
                     /locus_tag="L1V17_001332"
     CDS             2951..3286
                     /locus_tag="L1V17_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236111.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            3519..4460
                     /locus_tag="L1V17_001333"
     CDS             3519..4460
                     /locus_tag="L1V17_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HBN1236112.1"
                     /translation="MSKSTLEMSHQEWLEDRKKGIGGSDVGTILGLNKWKSPYQLWLE
                     KTGQVVLEESGSEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPIIDGSQATADFLKEKYADVEDVQTT
                     LPIHFDELVEQKNELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEREIK"
     gene            4462..5352
                     /locus_tag="L1V17_001334"
     CDS             4462..5352
                     /locus_tag="L1V17_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HBN1236113.1"
                     /translation="MATNESLKNQLAAKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            5395..6195
                     /locus_tag="L1V17_001335"
     CDS             5395..6195
                     /locus_tag="L1V17_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBN1236114.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWNLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADNIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            6210..7061
                     /locus_tag="L1V17_001336"
     CDS             6210..7061
                     /locus_tag="L1V17_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBN1236115.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            7262..7723
                     /locus_tag="L1V17_001337"
     CDS             7262..7723
                     /locus_tag="L1V17_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBN1236116.1"
                     /translation="MPKILDACCGSRLFWFDKNNSDVTFMDCRQQYEELSTGHVINVD
                     PDVVADFRDMPFEDDVFDMVVFDPPHLRHVGENSWLAKKYGKLDELWPEDIRQGFAEC
                     MRVLRPSGTLIFKWNEEQIPLSDVLEAIGEQPLFGNKRSKTHWLVFMKKFS"
     gene            7749..8201
                     /locus_tag="L1V17_001338"
     CDS             7749..8201
                     /locus_tag="L1V17_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236117.1"
                     /translation="MKIVLNKCFGGFGLSHEAKMEIFKRKNIEVFPYINNFSYDSDDE
                     YTRYTGQKLGSMDFIYYFKKDPKIDKVTGIYSEIDRLYGIADDSSFSSDSNRGDKDLV
                     AVVEKLGSEASGPYASLKVVDIPDGAEWEISDYDGVETAHYGFQTGSI"
     gene            8307..8501
                     /locus_tag="L1V17_001339"
     CDS             8307..8501
                     /locus_tag="L1V17_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236118.1"
                     /translation="MDASEVVNKINSLKEVFGDVEVVINAQGYDNGFFKQITDISIQQ
                     GMEDEDGNFIDEVAILVTCE"
     gene            8532..8918
                     /locus_tag="L1V17_001340"
     CDS             8532..8918
                     /locus_tag="L1V17_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236119.1"
                     /translation="MKKLHQLISEKESELQNLEDSLGLGFPIVEQAKMTQISHLRLEL
                     EDLRQIEKSIQLNDNQKIVLEWLKSETILTREAPILSVNAFSDKNLLGKLPDKVRKAY
                     KLLACKQEYEVLSAFAQWGLEQEEAE"
     gene            8915..9118
                     /locus_tag="L1V17_001341"
     CDS             8915..9118
                     /locus_tag="L1V17_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HBN1236120.1"
                     /translation="MNNRHRRITKLRKQELNVLKTKFEKEYGISAEETYKVASQFVAD
                     ASNAIRKFGISILNDDRKWEEMR"
     gene            9115..9411
                     /locus_tag="L1V17_001342"
     CDS             9115..9411
                     /locus_tag="L1V17_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236121.1"
                     /translation="MKIKDGFYASSHGIGGLMLDMPIKNPKTRQKSKFKIGDMVRCKA
                     EEFIYPFRGYVEHVYNHSAIIHIENTMECDKWLAKSKDNLAVARLVDMELINDK"
     gene            9487..9903
                     /locus_tag="L1V17_001343"
     CDS             9487..9903
                     /locus_tag="L1V17_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBN1236122.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCDVNKHSNYEI
                     GQLIRGYGEKNVEKLKSIALIEFAEAYKKGVLVQYR"
     gene            10164..10301
                     /locus_tag="L1V17_001344"
     CDS             10164..10301
                     /locus_tag="L1V17_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236123.1"
                     /translation="MDKEIKVTVKLDLTELKELLNKASDQVEQLQETLDEIANFKIQV
                     S"
     gene            10711..10941
                     /locus_tag="L1V17_001345"
     CDS             10711..10941
                     /locus_tag="L1V17_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236124.1"
                     /translation="MRNYWYISLTNEYPRTIDDCSVRVVRSVQIKKKYSIVEMTREAT
                     PKEIDKCKLLYCGHGFYDEPNIQNNINKNLRD"
     gene            11100..11933
                     /locus_tag="L1V17_001346"
     CDS             11100..11933
                     /locus_tag="L1V17_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small subunit of terminase"
                     /protein_id="HBN1236125.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELKSNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPKRNKNALKTGEYET
                     IFFDTLTDNEKDIYSSLNDDPSFALSEEIRLLKIRQLRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKTPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            11926..13341
                     /locus_tag="L1V17_001347"
     CDS             11926..13341
                     /locus_tag="L1V17_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HBN1236126.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPENMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTTVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            13353..14882
                     /locus_tag="L1V17_001348"
     CDS             13353..14882
                     /locus_tag="L1V17_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBN1236127.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEYMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKDPTAKAEYVTKKLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            14800..15852
                     /locus_tag="L1V17_001349"
     CDS             14800..15852
                     /locus_tag="L1V17_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBN1236128.1"
                     /translation="MTIETKYWTKRRELEDQARLKQENQTLKKLTSVFPEALKEIQAK
                     LLSQADLHNITYPEMMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            15854..16171
                     /locus_tag="L1V17_001350"
     CDS             15854..16171
                     /locus_tag="L1V17_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236129.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            16298..16921
                     /locus_tag="L1V17_001351"
     CDS             16298..16921
                     /locus_tag="L1V17_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HBN1236130.1"
                     /translation="MSMKHKSLMPMNLQYFAEGDDQKFSFDDFKSFVESNEEAQKFIQ
                     SQSQSVADKQLEAWKQNNLDKIKQDTIKEYEESKKNKSPEQIQLEKLQAEFEAEKALR
                     VTSDNKAFVAEQIAGLELDGELKESISQFMLNNLVSSDTDFTKNAVEGFTSVLNAINE
                     KHADALKELQMKSAFGGTQQSNNQVQQNNETLTNPEEQLGQILQQFN"
     gene            16936..17826
                     /locus_tag="L1V17_001352"
     CDS             16936..17826
                     /locus_tag="L1V17_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HBN1236131.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            17849..18064
                     /locus_tag="L1V17_001353"
     CDS             17849..18064
                     /locus_tag="L1V17_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236132.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            18076..18417
                     /locus_tag="L1V17_001354"
     CDS             18076..18417
                     /locus_tag="L1V17_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236133.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            18417..18788
                     /locus_tag="L1V17_001355"
     CDS             18417..18788
                     /locus_tag="L1V17_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236134.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            18781..19176
                     /locus_tag="L1V17_001356"
     CDS             18781..19176
                     /locus_tag="L1V17_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBN1236135.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGAVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            19178..19555
                     /locus_tag="L1V17_001357"
     CDS             19178..19555
                     /locus_tag="L1V17_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236136.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNKPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            19556..20164
                     /locus_tag="L1V17_001358"
     CDS             19556..20164
                     /locus_tag="L1V17_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBN1236137.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            20164..20505
                     /locus_tag="L1V17_001359"
     CDS             20164..20505
                     /locus_tag="L1V17_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236138.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGPVVEEAAEVMEG
                     MQNAVDGKSVSEALSRAYSFIADILFEGQFTGEDYRQGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            20747..23536
                     /locus_tag="L1V17_001360"
     CDS             20747..23536
                     /locus_tag="L1V17_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBN1236139.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANSFVLIIGAVVGAI
                     AVFGYFMATNEELRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNGIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFVSYFTNIYFAALNI
                     WTGFKLTLINIWNEVVNQAKSIWLNIKYFFINLWIDIKYFAIQKWIELKFSIIQTWID
                     LKYNAITTWNNIKQFFKDTWKNIKDTAYNTWISIKNTMINTWNNIKDSFWNIVTGIVN
                     SAENAWTNLKNGVSNAINRVKEIFNSLREVNLFEIGKNIIDGLINGVKEKWNALKDTI
                     KGIAGNIKNWIKGALDIHSPSRWMRDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKTP
                     SVQPVVNGISHLPITQTKQNISASETKEIHLHLNVYGDLPDSMVRKITTKIKTELTRQ
                     MKRDAGAVGGTLYAT"
     gene            23526..24266
                     /locus_tag="L1V17_001361"
     CDS             23526..24266
                     /locus_tag="L1V17_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBN1236140.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYKNVTRKIECYYKAPSIDMVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            24263..>26100
                     /locus_tag="L1V17_001362"
     CDS             24263..>26100
                     /locus_tag="L1V17_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBN1236141.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCEIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLVEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRIIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     VLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSVGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWR"
BASE COUNT         9480 a         3714 c         5322 g         7584 t
ORIGIN      
        1 ttaaatctga tagtgtttct tccttactta atataaatct ttctctatca tgtaatttat
       61 ttagtttttc atcatttttt tgttctaatt cataagcttc tttttttatt gtgttagctt
      121 tcgacagttt agtgattcct ataattaata aaataagtcc aatcaataat aacattcaaa
      181 actcctcatt tctttgatat aattattgta gagtttactc agaaatgagg aaagagtcca
      241 tgtgaaagca tgggcttttt tatttttaat gttgtaatac taaatgttca agattatgag
      301 gaagccctaa atattcaata atttggaact gactcatatc agataaatct tgttcatcta
      361 ttgttctagt taacatttca attgcaaaca tattagcttc agcttctata ccataaatca
      421 tacaactaag gttgtttgct ctaaaagctg ctgtgcaaat acctttatgg agtctaacgt
      481 gggctatttc atgccataat acaaatcttt tcatagaagg tgataggttt tgattaatta
      541 atatcacata acatctttta ttgtgtatcg tttgtcctaa tgttttattc cctaaatcag
      601 tttcaattaa atctatatca gaatatttga ttattttata tggattaatc gcatcagatc
      661 caaactctac aaataatttt tctatttctt ctaatatcca gtatttgttt aaatgcatac
      721 caaagcccac ctattgacga tattttttag gagtgaattt tttctttgct ttaactttgg
      781 ttaaggcaag tgcaagttga atggcatcgt ataatttttc cttatcttca tcgtctaaag
      841 gttcaccata ataatttgtt tcagcatctg aattcaagcc ttcaagtaat ttttcagctt
      901 gtaaagcaat atcttgttta tctttttctg ttaaatcata ataatggcgt ttatcagtac
      961 gtcctaaaag ataatcagtt gatacattaa agtaatctgc aactttttgt attttatctc
     1021 cagatggagt acttttattc catctagaca tgcttccatt tccgaaattt aactttcttt
     1081 caagttctgc caacgtcatt gaacgttctt ttaataagat ttttatacgg tctaatagca
     1141 taggatatgc attcctttca aaataccgac aaaaaaagta tttttctgca aattatctat
     1201 ttacaaatag agaatttgca gttatactag ttttgtaagc aagatattta cggcatacaa
     1261 agactaaaag caataaacta atagtctccc cagacatcag taagctcgct ttttgtgcgc
     1321 tgtattttgt atgcttacat aatagcatat ttgcagtttt tgtcaaactt attagacaaa
     1381 aatattagaa aatattcgat aagggggtat gaagcatgac tttaaaacag caagtattaa
     1441 ttgctttagt aaagaaaggt tggagtcaaa gagagttagc tcgacgaatg ggtatatcaa
     1501 ttacttattt acgagatatc ttcatcgaaa aaagaaaacc taaggaacgt ttaaaacaaa
     1561 tcgaagaact tttggatatc aagttagaag tagattctaa tgatcagcca tcagaacagg
     1621 aggcgtaaaa atggtacaac gtttgagcaa agcggagttt aaagagaaat ataagtattc
     1681 tgaaagtact tatcaaagaa gaatgaagga atttaaaaaa tcacgtttta gtgaggggta
     1741 taacgcagtt acttccaaag aaataacaat tgatgtcgat ttatatgaac agtttagaac
     1801 atggcgttct aaaaatcgat ttagagttag agctgtttgt taatagctaa aaaatctaaa
     1861 ttcaccactt ctgaaaagag gagttgctgc tctcctttca agtttgccaa agtccacgtt
     1921 ttttcatttt ggcaactcct cttcttggag gtggtgacgg cgagagacga aggagggatg
     1981 acatgaagga agaatcaaaa atagggattt tgaatgagaa caattacaca agattaatta
     2041 ttgaaacaga agaagggaaa aaagtagcag aagttacatt gaccgatgca actcctgctg
     2101 acggttatcg tattcgatta actcctaaat atgattaacc ttttggtggg tgtggatcgt
     2161 ttccgtgact atcacggctt tgaatttttc catctctgcc atgaataaat agctcagatc
     2221 cttgattttt agaaatctct ctagcgattt ttactgcttc tgattttgta ttagtatgtg
     2281 cagtcgcttt agaatttcca gcacctttga cattccaacc accattggaa ttaggtacaa
     2341 catgttgatt ttttcccata gttttcacct ccatttctat agaaatattt tatcaaatag
     2401 aaatggagaa attcaataaa cgaaaggaga agtgatatgg catatacctt gcaacaagaa
     2461 catcaaattc tcggtttgat taaacaacgc aggaaacaat tacaagatga ccgtgcagcg
     2521 cttagaaaag ccgatgagct atcagatagg caagctgaac taattgcttc tgaacttgag
     2581 gatttgagaa tgctagaaat aaaaaatagg gagattagat tatgaagaag acagacacac
     2641 tttttatagg attcattttg gggttattag tgattgtagc gcaccaaagt attatcgggg
     2701 gaagcttgtt cgcagcattg atggttttaa tcaatctgct tgattcaaaa gaaaggagca
     2761 actatggcac gagaagaagc gctaaaaatc ggtaaagtga ttgctgataa tcggtgggga
     2821 aatagccgcc ctattatttt aagcaagcaa catatcgaaa agcaaaaagc atggcaacaa
     2881 ataaaaaagt gactctgcca gccagcaaag agtcacatac aaatttataa aactaggaga
     2941 attatatcac atgaataaga aaattgaaaa tcttatcgaa gaattgaaac gtgaatgcca
     3001 aaagcaaggt gtttctatta tttgtacagc ccaaaaagaa ggggaactta aaagtctcgt
     3061 ttatggtgag acaacagaaa ttttactttg tcttgctatg caagaagaac atttagatga
     3121 aaatctccca ttgtcagcac atattatgcg tagaattgct gtggatgctt acgaacaagc
     3181 gaaaaatgaa gaagaaaatc aaccttcaaa tcatactttt gttattaata acaaggaaga
     3241 tttagctgat gtgatgactc gtattctcaa gggggaattt caatgatgaa tgaaaaaaca
     3301 attgatctac tcattatttt atttttcacg ttagtgattg tagcgaaaag ttatgtaatc
     3361 tttggcttgt tattcgcaat taccatgctt gtgctttgcg tgttagcaag cagaaaagag
     3421 gttaaacatg aacgagttag caaatcttga caactattta actgatcctg attatgctaa
     3481 accaccatat gaagcaccaa ttgatgagga ggatgaagat gagtaaatct accttagaaa
     3541 tgagccatca agaatggctt gaagaccgta agaaaggcat cggaggttcg gatgttggaa
     3601 caattttagg attgaataaa tggaaatctc cttatcaact atggctagaa aaaacaggac
     3661 aagtagtact tgaagaatca ggaagtgagc ccgcttattg gggtaatgtt ttagaagaag
     3721 tggttgctaa agagtttcag gaacgtacag gcaaaaaagt acgcagaaga aaccaagtat
     3781 ttgaacatcc attacatcca tttttaagag caaatattga tcgggaagta gtgggagaaa
     3841 atgccattct ggaatgcaaa acagctaatc aatttctcgg taaagaatgg gaaggcgaag
     3901 aggtaccgct tagctatctc tgtcaagttc aacattacat gaacgttcta aacaaagact
     3961 attgttacat cgctgtctta atcggtggtc aaaaatttat ctggaagcgg attgaacgag
     4021 atcaagagct gatcgataca atcactgaac aattagtaga gttttgggaa acaaacgttc
     4081 ttggaggtat cgagccaatt attgatggta gtcaagcgac agctgatttc ttgaaagaga
     4141 agtatgcaga tgttgaagac gttcaaacga cgttaccaat tcatttcgat gaactagttg
     4201 aacagaaaaa cgaactcaaa cggactaaga aagaaattga atcagctatc cgtcaagtag
     4261 acaacgagat tatcagcgag ctaggtaaac gtgaagccag tatcggtatc actcaaaaaa
     4321 acatcatcag ttggaaattt gtccgtacga gacgtatgaa ctcgaagaaa ctagcagaga
     4381 aatatccaga tgtcgcaaat gatgaagaga tttataacgt tactgaatca agaaggctaa
     4441 ccgaaaggga gatcaaataa tatggcaaca aatgaatcgt taaaaaatca attggcagca
     4501 aagccacaga aacaagttgc accaggtcaa ttaggactta aagctttgat gaatacacca
     4561 acaatgagaa agaagttcga agaggtgctt catgacaatg ctaatgcttt tatgtcgaat
     4621 gttatgactc ttgtatctaa tgacagttat cttgcagata gtgaaccgat gtctatcatg
     4681 agtggtgcgt taactgctgc aacattaaat cttgggctag ataagaattt aggttatgca
     4741 tatttagttc cattcaatag taaaaacaag caaacaggaa aatgggaaaa gaaagctcaa
     4801 ttcatgcttg gctataaagg atatatccaa ttagcccaac gatcaggtaa atacaaagca
     4861 ttaaatgtga tcgaagttta cgaaggagaa ctaaaaagct ggaaccgact gacagaagag
     4921 tttgagtttg atccaaatgg tagaacgtct gatgaagtca ttggatatgt tggctatttc
     4981 gagttactga atggattcaa aaaaactgtc tattggacca aacaagaaat cgaagctcat
     5041 cggattgcta acaataaaga tcgcgataag acaaagttaa gtggtgtgtg ggcatctgat
     5101 tacaatgcaa tggcacgaaa aactgttttg agaaatcttc tttctaaatg gggaatcttg
     5161 tccatcgaaa tgcaagaagc caccacatcg gatgagagag tccaaagggt tcaagaagac
     5221 ggcagcatta ttgctgaaac agaagttgaa gaagatattc ctgaaagaaa agaagcagag
     5281 gttatatctg aagaaaatga agatgtacaa actggattat ttgatgcatc taatccgccg
     5341 ttaaacaaat aatgagggag ctttctccct tgcttttcta gaggagaaat acgaatgaac
     5401 acaggatatg tcaaattaca tcgaaaagtg atgaattcat tcgtttggac caatccttat
     5461 atgtataaat tatggaactt gtgtttgatg aaagcgagtc atgagaatcg caagatactt
     5521 tttaatggaa aagagataca agtgaacagc ggagaattcg tcacagggcg cgatgctatc
     5581 acatctgaga tgaacgaagg cgtgaaacgt gaacatcaag tgaacagcgg ttctgtatgg
     5641 agatggctaa aacaatttga aaaaaacgga atgttgaaca tcaaatcaac tacgaaatac
     5701 agcgttatat caataaaaaa ctggtctttg taccaaagca gtgaacaaca aatgaacatc
     5761 aaacgcacaa caagtgaaca acaagtgcac acaaacaaga atgaaaagaa ttataagaat
     5821 gaaaagaata ataaaacatc atcgtcgcaa ccacgcaaaa agcgtgttta cgacaccgac
     5881 tcagtttact acattctcgc ggaggagtta ttcaaacaga tttgtcagaa tcaggaaatc
     5941 aaaaagccga atctgcaaag ttgggcagat aacattcgga aaatgatcga gatcgacaag
     6001 cggaccgaaa accaggtacg gggaatgatt gaatggagtc agcacaatgt gttttgggca
     6061 tcgaatattt tatctgctaa aaaattgcga gaaaaatacg acacaatggc agcgcaagcc
     6121 aatcgtgatt ataaaacaaa acaaactaaa acgcttgaat acgagaaatt tagcacagat
     6181 gagttgccta tttgagagga ggcgtaggca tggaaactgt tggggaaatc atggaaaagc
     6241 tgatacagaa agtgcttgtc caacgtggcg aatgtcctga atgcggacag cctttgtatg
     6301 gatggcgtac gaagaaccct gatggctcag aacgttgtaa gccaacctgt atgcaatgtg
     6361 ggtataaagc attgcgagtt caggaagact tacaaacaga acgaatttac aacgagagcc
     6421 tgaaagcaag agcaatcaat tttttcaaag gtggttctgt tgtgcctaat caagcgttgt
     6481 ttgattgcac attgcagaat tatcaaattg tcgatcaaga aacaagacaa gcggttgaag
     6541 taaccaaacg ctttgttaat tcagtcttgt taggaaatcc aagtcacctt gttttaactg
     6601 gaaaacaagg aacaggtaaa agtcacctag cgatggcagc ggcttgggaa gtcttgaagc
     6661 gatcaaacta cgataaaaaa atcttattta tcgggttaca ggaaatgctg gatcaaatca
     6721 aattttcgta caacaatcct gaactcagaa aaacgattga gggatcgttg attgcagata
     6781 tcaaaacagc ggatttagtc atcattgatg atatcggttc agaactagga aaagatgcat
     6841 cagatagtcg agcgtttggc ataaacacgc taaattcgtt cttggatgca cgacagaacc
     6901 tagcaacgat tatcacaacg aacttgcttg gtgaagaact gaaaaaagct tacggtacga
     6961 gaacaatatc aagaatgttt gtcaactctg atggatttac gatggtattt tctcaaacag
     7021 cagacaagcg cataaaacca gtcaaaggag cgatcgcatg aatttgacta aacaagaaaa
     7081 aagaatctgt cgtcagataa tgttgcaaat tataggtgat cgtgacatgg acgaattatc
     7141 tcaacaagag agtcgaatgg ttcggaagat aagtaagcta attatttatc gggatacaga
     7201 aagatttctc actgttttag gtaacgtcta cgagaatcca gagttattgg aggtagagta
     7261 attgccaaaa atattagatg catgttgcgg tagtagattg ttctggtttg ataagaacaa
     7321 ttctgacgta acatttatgg attgtcgtca gcagtatgaa gaattatcaa caggtcatgt
     7381 gatcaatgtt gatccagatg tggtcgcaga ctttcgcgat atgccttttg aagatgatgt
     7441 gttcgatatg gttgtatttg acccgccaca cttaagacat gtcggcgaaa actcatggct
     7501 tgccaaaaaa tatggaaaat tagacgaact ttggccagaa gacatcaggc aaggttttgc
     7561 agagtgtatg cgagttttac gaccttcagg aacattaatt tttaagtgga acgaggaaca
     7621 gataccactt tctgatgtgt tagaggctat tggagaacag ccattgtttg gtaataaacg
     7681 aagcaaaaca cattggcttg tgtttatgaa aaaattcagc taacggagga aacaaaggag
     7741 gaaaagtaat gaagattgta ttaaataaat gttttggtgg ctttgggttg agccatgaag
     7801 caaaaatgga aatttttaaa agaaaaaata ttgaagtatt cccatacatc aataacttta
     7861 gctatgactc agatgatgaa tacacgagat acacaggcca aaagctaggt tcgatggatt
     7921 ttatctacta tttcaaaaaa gacccgaaaa tcgacaaagt tacaggaatt tatagcgaaa
     7981 ttgaccgact gtacggaatt gctgatgatt ccagtttttc aagtgattca aacagaggtg
     8041 ataaggacct cgttgctgtt gtcgaaaaac taggaagtga ggccagtgga ccatatgcaa
     8101 gtcttaaagt cgttgatata cccgatgggg ctgagtggga aataagtgat tatgacggcg
     8161 ttgaaactgc acattatggt tttcaaacag gtagtattta gtccactaat gacaactaaa
     8221 gaggaggcag aaggatgagt gaagatgaat actttgaaca gtagtctatt aacgacagag
     8281 atttttaact ggaaaggggt gtagtcatgg acgcatcgga agtagtaaat aaaattaata
     8341 gtctcaaaga ggttttcgga gacgtcgaag tagtgataaa cgcacaaggc tatgacaacg
     8401 gattttttaa gcagattacc gacattagca ttcagcaagg aatggaagac gaagatggaa
     8461 actttatcga tgaagtagcc attttagtga cttgcgagta agtaattgac agctaaagag
     8521 gaggcagaag gatgaaaaaa ttgcaccaac tcatatctga gaaagaaagc gaactccaaa
     8581 atttagaaga tagtttggga ttggggtttc caattgttga gcaagctaaa atgactcaaa
     8641 tcagtcatct acgacttgaa ttggaagatt taagacaaat agaaaaatca attcaactca
     8701 acgacaacca gaaaatcgtg ttggagtggt tgaaaagcga gacaatttta actagagaag
     8761 caccaatatt atctgttaat gctttttctg ataaaaattt actaggaaaa ttacctgata
     8821 aagtacgcaa agcttataaa ctattggctt gtaaacaaga atatgaagtc ctatcagcat
     8881 tcgctcaatg gggattagaa caggaggaag cggaatgaac aacagacatc gcagaataac
     8941 aaaactaaga aaacaggaac tgaatgtact aaagacaaag tttgaaaaag aatatggaat
     9001 ttcagcagaa gaaacatata aagtggcaag tcagtttgtt gctgatgcga gtaatgctat
     9061 tcgtaagttt gggatttcga tattaaatga tgatcgtaaa tgggaggaaa tgagatgaaa
     9121 ataaaagacg gattttacgc tagtagtcat ggtatcggcg gtttaatgct agacatgccg
     9181 ataaagaacc ctaaaacacg tcagaaatca aaattcaaaa tcggtgacat ggtccgatgt
     9241 aaagcagaag agttcatcta tccgtttcgt ggatatgtag agcatgtcta taatcattca
     9301 gcaatcattc acattgaaaa cacgatggaa tgcgataagt ggttagcgaa aagcaaagat
     9361 aatttagcag tggctcgttt ggtggatatg gaactaatca atgacaaata aaaaagccgg
     9421 atcgctccga ctgattcaat aaatccaaca catttattat atcacataaa ggagcggttt
     9481 gacttgatgc aattgttacg agaggtagat ttcaaacaga caagatgtaa tgcgagagat
     9541 gtgctgaaga actttcggcg tttggagcgg atggcaggtc gctctttgat agatattaag
     9601 tcgccgatta ttacggatat gccgaaggca ccgaagcacg gcaataaggc agaagacgcg
     9661 atcattcaga tgatggatat agaagcggag agagacgcaa tactagcggc tttgatggct
     9721 cttagtctga ttagccgtca gatactctac tacagcttct gtgacgtaaa caagcactct
     9781 aattatgaaa tagggcaatt gatacgagga tacggagaga agaatgtaga gaagttgaaa
     9841 tccatcgcat taatcgaatt tgcagaagca tacaaaaaag gcgtgttagt tcagtatcgt
     9901 tgattttgta gggtttttgt agggatagtg tagggttttt gagcggttta acgtgatatt
     9961 atggtagtgt cgaaagatta gtgataggtc tgagacaaaa taaaatgtaa gggaggaaat
    10021 ctccctcatc gttttaactt aagcttcgat agacagcaac ggaaatatta agaataagga
    10081 tgtgaatttc aactccttct aaattgttct tattatctat catccgttgt tgtctattaa
    10141 tttatgcatc ggaggaaaaa cgaatggata aagaaatcaa agtaactgtc aaattagatt
    10201 tgactgaact aaaagaactg ctcaacaagg ctagtgacca agtcgaacag ttacaagaaa
    10261 ctttagatga aattgctaat tttaaaatcc aagtttctta gcagtatatt ttttagcagc
    10321 tgcactcata aaatcatacc aagtatcaga aaaatataac ttaactaaat aattaaaaaa
    10381 ggtgggtaaa tagaaatgac ggcgttaata atttcaattt ttgcgctctg tcttaatgtc
    10441 tatatgattg gatttaaaaa tggacaaaat aaaaaatagt agcagccgag aataatttta
    10501 tagtgtcact gtggcggaaa tagaagacgc aaaggtggag gtaggaagcg tatggcgcac
    10561 tatcgggacc ttgtacaaaa ctagaaagga ctagtacgtg tgtggtgcga gccctaggga
    10621 ggaacaggat aaccgcctgt gtgtaggttg ctattacata ttagatcact ctttgagtgg
    10681 tctttttatt tacataaagg aggctacata atgagaaact actggtatat atcgctaact
    10741 aatgaatatc ctcgaaccat tgatgattgt tcagtgcgtg ttgtgcgttc tgtccaaatc
    10801 aaaaagaagt actccattgt tgaaatgacc agagaagcta cgccaaaaga gattgataaa
    10861 tgcaaacttc tttattgcgg tcatggtttc tatgatgaac caaacattca aaataatatt
    10921 aacaagaatt tgagggatta gaatgcaaga aatggcttaa aaatctccaa tcaggacaaa
    10981 tcaagttaga caaagtttcc gatttaaaga tattgattga agctgattta atgctaaaag
    11041 atattgaaaa ttagaaaaca aaactcaacc taagaagatt gcgaggtggt gtgtattgaa
    11101 tggcaagaca acgtgatcca agacgtgatg aagccaaaag aatttggtta gaatccaacg
    11161 gagaaaagca gttaaaggaa attgcatctg aattaaatgt ttcagattct caggttagaa
    11221 aatggaaatc gcaagacaaa tggagcgctg aattgaaaag taacgttacc aatggcaaaa
    11281 gtaacgttac taatcaaggt ggcgctccta ttggtaatca aaatgctaaa ggtaacaaag
    11341 gaaacagcag agcatcaccg ccaaagagaa ataagaatgc tcttaaaact ggtgagtatg
    11401 aaacaatatt ttttgacacg ttaaccgata atgagaagga catctattct agtttgaatg
    11461 atgatccttc ttttgctttg tccgaagaaa tacgacttct taaaataaga caacttcgaa
    11521 tgatgaaaag aatccaacaa gctgaagctg gactaaatga tgaagaagtc gaacgattgc
    11581 agcagctaag aaagattaaa actccgattg aaaaaaatgg taaaaagcta gaaatcaagc
    11641 gtgaggttat gcaagatgtg cagattagca gaaaaaaaca tcgcaaaatt gatgatattc
    11701 tttcaattga agattcattg actcggatta gcaaccagtt agctaaagcc atcaagcaaa
    11761 tgaatgaact ttatatgaat gaatacagaa ctgatttaat taaagctcag actgataaga
    11821 tccaagctga gacaaatgaa attggcggaa ataattcagg tgaagaaata gaagaatgga
    11881 aacaggcagt tttaaatgcc gcaaacaaac gggcggtgaa agaaaatgaa taatgaattt
    11941 attccttttg ctgatattgg ttctgccatt gattattact atgataaacc agtagctttt
    12001 tgccaagata ttttgcattt gaatcctgat gaatggcaag aaaatgtttt aaatgattta
    12061 gctgaatttt caaaggtttc tgttcgttct ggtcaaggag ttggaaaaac agcattagaa
    12121 gcaggagcaa tactttggtt cttaacgtgt cgaccctacg ctaaagtaat agcaacagct
    12181 ccgacaatga agcaacttta cgatgtactt tgggcagagg tagctaaatg gttaaatgat
    12241 agcttgatca aaaacttact gaagtggaca aagaccaaaa tttatatggt tggtgattca
    12301 gagcgttggt ttgctacggc tagaacagcg actaaaccag aaaatatgca aggttttcac
    12361 gaggaccata tgttgattgt ggtagatgaa gcttctggtg tgtctgatcc aattatggaa
    12421 gctattcttg gtacgctatc aggttttgat aataagctgt tgatgtgtgg aaaccctaat
    12481 aatattgaag gtgtctttta cgattcccac aattcagacc gtgataaata cagagttcat
    12541 aaagtatcaa gctatgatag taaacgtaca aacaaagaca atatagaaat gattcttaaa
    12601 aaatatggaa aagaaagtga tgttgctcgt gtccgtattt ttggagaatt tcccaaaggt
    12661 gcgttggatt catttatcag tcttgaaacg gttgaattgg ctacagaaaa acaaattagt
    12721 gattctttag tcaataaaac aacggttgct catattggtg ttgacgtagc tcgatatggt
    12781 gatgattcta cgattctctt tcctagaatt gctaccaggg cattggagta tgagaagtat
    12841 tcaaaacgta gcactatgga aacaacagga tatgtcatca acatggccaa gaatctaatg
    12901 agtcaatatc cgagtattga taaagtgatg attaaagtcg atgacactgg tgtcggaggt
    12961 ggtgtaaccg accgcctaga agaacttata gaagacaagc attatccttt tgaggtgttt
    13021 ggagtgaata acggttcaac atcagaagac gatttttacg ataatttagg tactcaacta
    13081 tggggaaaca tcaaggaaat gttagaagaa aatatgacag caaatcttaa cggagaacag
    13141 cctgttattg aattgccttc tgatagttcg ttaatcaaag aattaagtac tcgcaaattc
    13201 aaaatgacaa gtagaagtcg tatacgttta gaaagtaaag atgatatgaa aaagcgaaat
    13261 attggtagtc ccgatattgc tgacgcactg gctttagcgt tttatgagcc accaagtcac
    13321 tatcaattta ttcaatttta ggaggtgagt ttttgattag tacagtatta tctttagaga
    13381 gatataagaa gctacgtgtt aaatatgcaa cacaaattga agatggaatg tttgatccga
    13441 atggttttat agaatatatg aaaccatttt ttgctgatcg cgaaagaaaa tatctagctt
    13501 atactagcga aaagaatgaa atagacaata gaccaaagcc taacactgat attgtaaaag
    13561 ttaataataa acttcatgct ggtatgtatt caattgtcgt agaccaagca gtcaatcatt
    13621 ttactggtat acctatcaaa tgggattacg atgtatcgga acaaaaaaga acactcattc
    13681 aaagattaaa agataaattc ttaaaaaatg atatagaact tccaacagtt ccagaagctt
    13741 ttaacaaatt aacaagcaat cttgattcca tgagattcgc aatgcttgat tctgaaactg
    13801 caacttttca aggagcttgt ggagtagctt tccgattgtt agagcctgtg gaagaagatg
    13861 atggttggaa gttaagagca agtaatattg aaccttggag agcagaaaga tatggaaatg
    13921 ccggaatcta tatcaaagaa aagtatgact cttaccagaa aaaatttttt caagaaatga
    13981 aagttatgac aagaaataaa attctgacat atgcttgcta tggtgatttg aattttgtta
    14041 caagcggaac gttcaaaaaa attgatgaga ccgataaccc tttggggacg attaccttgg
    14101 cagaatttaa aaataatacg aatcgttatt gtgattttga agtagctgag gaaattggag
    14161 atgcaattga tcgtgctttg tctgatcaac aaaacgaaat cgaacaattt aagcttgcgt
    14221 acatgcttgt tactggcaca acaatgagca aaggcactgc taaagaaatg atgaatcagc
    14281 tagggattat caacttaaaa gaccctactg caaaagctga atatgtcaca aaaaaattag
    14341 caaaagattt caatgaatat catatggatc tattgaaaaa acagttttac accatttgta
    14401 aagcaatcga ttttaacgat gaggtgttta aatcaaacag ttctggagaa gctcgcaagt
    14461 ggcaaatcat tagcctagaa gcgaaaacaa atactaaaga gcaatatttt agagaaggat
    14521 tgaaagaatg cgcagaaaca attgctgctt ttcttaagtt tcatgacaaa gtagaaattg
    14581 agcctgaaaa aattattttt actttctcta gatctttgcc aactgattta agttatttag
    14641 ctgaagcttt acctaaactt gcaccatacg tatccaaacg aactattcag agccaaattc
    14701 catttgtaac agatgttgat tatgaaaatg aaatgatgga attggaaagt ggaagtgctt
    14761 atccagatag tgaatacaat tttggcggag gtggcaatag tgacgataga aacgaagtat
    14821 tggaccaaac gtcgagaact ggaggatcaa gcaaggctca aacaagaaaa tcagacactt
    14881 aaaaaattaa ctagtgtatt tcctgaagca ctgaaagaga tacaagcaaa actattatca
    14941 caagctgact tacacaatat cacttatcca gaaatgatgg agttttacag tacaagtaat
    15001 cagaaaaaat atcgtgaata tgtggaaaaa aattataagt cattaaaaat gtatgatgca
    15061 aaatacaaag agtttatcga tgaatttttt ccaccatttg actatgcaaa agtcaatcgc
    15121 ttattacaaa tacgatcaga tgtatttaaa attcttgcag aatatgcgat ggatgcagat
    15181 gtgaatcaat atttttctga tcgcttagag gaaattcttc aaagaacata ttcttctaat
    15241 gctaatgttt ttgttcaact tttaaacgtt gatataccaa attatttacc agaaaatgaa
    15301 attaaacatt atttgaacta tccatggtca ggaaagacat tttcaagaag actttgggga
    15361 aatatttcat cgcttgaaca gaaactctct aatgctattg taaaaagtgt tgctagtgga
    15421 gaaggcgtta tacacgcatt aaacaccatg agattagact cagaaatttg tgacatgttt
    15481 aagttagaag aatcaaagta taacaaagcg atagaaaatc tcgttcgaac ggagtatgca
    15541 aaatttgcac aagatggtat tgaaaaatca tatttagaaa caggtattga ggaatacaac
    15601 gtattgactg caaaagatga gagagtttgc cggatttgtg gaggaaaggc aagtaagaat
    15661 ccctataaac tgaaagatgc tgtcataggt gaaaatcgag cacctttcca tagtcgttgt
    15721 agatgtacgg atgttcctaa tttaccaaaa ttaggaaagg atattgatga agaatatgac
    15781 cgtttatttg gcgatttatt agatgagttt gcacatgatt cttttggaat taatttgaaa
    15841 cggaggaagt agaatgaaag atttttttga agcagtacta acaattaatg taaatgctga
    15901 tattgcagaa gcctacaaaa cagctattga gtctgagaac catcctaatg gcttgagaga
    15961 ccattggaat ggcaattatg cctacgtggt tattggcgat caaactgtta attatcaaga
    16021 taatactcca gttgataaga ataccgttaa tttaacgatt caattattat ctcattcatt
    16081 accaaattta aaagaaacag ttgattggta tgaaaagatg ggatgtattg ttgttagaac
    16141 tgactacaaa gaaggaaagt ctagtaatta ggctttttta ttttgtccga aatgacgtta
    16201 aactagcgca atactgggct tggttgaatg gtggggcgca actattaaaa ctcaaagcaa
    16261 tgcggggcgt gaaaacgaat cgtggggcga aaggagaatg agcatgaaac acaaatcatt
    16321 aatgccaatg aatttgcaat actttgccga aggtgacgat caaaagtttt cttttgatga
    16381 cttcaaatct tttgtggaat ccaatgaaga agctcaaaaa tttattcagt cacaatctca
    16441 aagtgttgcc gacaaacaat tggaagcttg gaaacaaaat aacttagata aaattaaaca
    16501 ggataccatc aaggaatatg aggaatctaa gaaaaacaag tcacctgagc aaattcaact
    16561 ggaaaaacta caagctgaat ttgaagcaga aaaagcgttg cgtgtgacaa gtgataataa
    16621 agcatttgtt gcagaacaaa ttgctggatt agaactagat ggagagttaa aagagtctat
    16681 ttctcaattt atgctaaata atcttgttag ttcggataca gatttcacta agaatgctgt
    16741 tgaaggtttt acaagtgttt tgaatgcaat taatgagaaa catgcagatg cattaaaaga
    16801 actacaaatg aagtctgcat ttggtggaac tcaacaatcg aataaccagg ttcagcagaa
    16861 caatgaaaca ttaacaaatc cagaagaaca attaggacaa attcttcaac aatttaacta
    16921 ggagagtgaa aaattatgaa aaaaacatct ttaaataatt tagagtattt ggatatttca
    16981 ccagcgatta atgctatgca agtaccaaat acaccttttt taagctattt acttggtgct
    17041 ggaaaaacag agccagcaaa ctcgacagaa attaaatggc gtgaatatga tatcaacaac
    17101 gatgattctt ctgaaaaact tgagggcgga gaatatccag atgctgaatc aggtcgaact
    17161 tggtttaaca actatactga aatttttaga aaatcaacct ctgtatctgg tacattagat
    17221 gctattaatg tgaatggagt cggaaatgaa ttaactaatc aagtagcact acgtggtatg
    17281 gaaatgaaaa ttgatttgaa ccgaaaattg attactggtg taaaagctga tgaaaatggt
    17341 tctaaaggtc gtcgaatgaa tgggattttg aacttgatca attcagcaaa taaggcagaa
    17401 acagccactg cgggtgcagt aacaagaaaa gatatcgata ctttatttaa attgatgtat
    17461 gaaaaaggtt atatgggaga aaaactatgc ttgatttctc cagatatgca ggagttaatg
    17521 actgatgagt tagatggaaa atcaacaaaa attgttcagt tcggggaaag agtaactttt
    17581 ggattgcaaa ttggaaatat cgtgtctaat tacggtacag gtattgctct actagaacca
    17641 tcattgccaa aaggaacaat tgccgcaatc gatactaatt atgtgaaact acgtccatta
    17701 cgtgaatgga gagcagaaga acttgcaaaa acaacggatt ctagacgtat cggtcttgta
    17761 ggtgaatact ctcttgaata caatgcttca aactctgggg caattttaaa tttaaagtct
    17821 gaataaaagg gagttagtac tccctttttt gataggagga attacagtgg taaaaaaaga
    17881 tgaaactaaa aaagatgaag tcgtgaaata tagagtaggt aaaactaaaa attttgttgg
    17941 gtttgttcat cctaaaactc gtagatttat cacagcagat tcaaataacg aatttatcat
    18001 ttctatagat gataaagaag caattgcaat tttggaagat gcaattgatg ttaatgaaat
    18061 ttaggaagtg atctgatgga tgaatcgcta aaaacggaaa tcattgagtc tacaaaagaa
    18121 gattttccag atttgagtga agaacgcata actaatttat tagaaataat tttgctagaa
    18181 attgaatcat acaacacttg taaaaatgat atttcatggg aaaagttaaa aagcgtgatt
    18241 agtgaagtgt tgtataaaat aataaaaaat gaatcagaaa aaacagtatc ttcagttaga
    18301 cgtggcgata caacgattag ttatgcttca acaacaaatg atgttagtga gttacttcta
    18361 ggctatggtg atttgatacg aagagttatt ggttgtggag gattggagtt tttttaatga
    18421 atgaagcaga tattttagaa actacttatg aagatagttg tattattgaa agactgacgg
    18481 acattgaaga ttctaataca aatattacta ttcaagatta caaaaaagta tatgataatc
    18541 ctatttcttg cgctctttca caaggtcaaa tcgatggact agcagtcata gaagatggag
    18601 agatggtaaa tgtttcaact gacacatata aattatttgt tcatcctaag attaaactaa
    18661 aaaaaggaga tcgaataaca ataactcaaa aggccagtgg cttaattttt tctctatttg
    18721 ctactaagcc tttttactat cctagtcatt gtgaagtgaa tttgatagga agtgagaaaa
    18781 atgggtaatc tcaaatatga atcaaatgca gaaaagatca ttgagaattt taaaaatatg
    18841 actgtaattg ctcaaaaaga aggaatatcc ttcgttaacg attcaatgaa taaagtcgtt
    18901 agtttagcta aaccattaac tcctgtaaaa tcaggtaatt taaggcgagg atatcgtgta
    18961 gtaaaagcta gaaaactatc aagcggtcga attgttggag cagttataaa caatgaacat
    19021 tattttaaat atgtagaaga aggtcatagg actaaaaatg gtggctttgt caaagggaaa
    19081 ttcatgttaa ctcgtgcaac gaatcttgca aatatgtctt atattcctcg aagatttaaa
    19141 caaatggcaa taaaaatcgt taagaaagga aagtaacatg aaagatgaaa tcattgctgc
    19201 aatcagtagc aaattaaaag aaatctatcc tgatgggaca atatatcttg attcagttat
    19261 gcagtcaact aaagattttt atttcgtttt atcagtaatg gaatctggaa ctgaaaatgt
    19321 aggaattgat attcaaaatg tttctttctt aattgatatt gcattgattg ataataaacc
    19381 taatagaaat ttaattaatg aattagtctc acgttgtggg acttttttta atacgattac
    19441 aatcgatgag caaatattat ttccaaaagc ctatttacct gatgaagcag atggtgttca
    19501 acatattcgt tttacattag aatttccaca atatattgaa tggagtgaaa gataaatggg
    19561 agaaaaaaga agtaaaaccg gaattatttc tgtcgaaaaa cctacttggt ttcctttgga
    19621 agatgagaca gggaattttc cggtatatgg tactgcgttg ccaatgggaa cagcagtaag
    19681 tatcaaacca acagctaatt atgaaacaac acaagattat ggggattcag tggttcaaga
    19741 tcaatttaca gcttttggtg gtgcagaagt tgaactggaa gcaaatggat atactcataa
    19801 agttttatct acaattactg gagggaaaat tgttaaaggt ggtgccttgc gttctggaga
    19861 agatattgcg caagatggtg cgtttgcata tagacgtaaa aaatcgaatg ggaaataccg
    19921 ttatacggtc ttttataaag gacagtttgc tctagattca gatgaaacat caacgattga
    19981 aggaagtaaa gtaagtttta ctcatccaac ttggaagggt tcatttgtag atgtaccagg
    20041 acttggatat atgtattcag ttgatgaaga tgatgaaggc gtggataaag caatgatcgg
    20101 aaattggttt acaaaagtag caattccaat tgaagaagca gaactttcag gaggtacaga
    20161 ataatgtcaa aatatcaaac aacgattaaa ttaacgaaaa aagatgaaga aggtaaatat
    20221 gagcaagtac aatttaaatc tgctgaattt ctaccaggcc cagtcgtaga agaagcagca
    20281 gaagtaatgg agggaatgca aaatgctgta gatggaaaat cagtatcaga agcattaagt
    20341 cgagcttatt catttattgc agatattttg tttgaaggac agtttactgg tgaagattat
    20401 cgtcaaggga tcgatgctcg agaaattgct tcgttgacag gtaagttatt aaaatctgtt
    20461 actgcaggct ttgatgaaac ttatacagaa acgaaaaaaa agtaagcgaa gctctcaaat
    20521 atcctttttt taaacattcg attacttatc gagaattaga tttaaagacg caattactcg
    20581 aagcaggttg gacgttacca gaaattgaac gtactgactt tgacgagtta atgcgtcttt
    20641 ttgcttttcg agatgcagta aaagagcatg aggatgttga gtactacgat aacttcaccc
    20701 aattttagga ggtgatactt tgaataacga tgacctaatt ctgaagatga tactagatga
    20761 atctggtttt actgccggta tgaataatgc tgtcaaaaag ttgaactctt ttgatgaaac
    20821 aatcgaaaga aaaagtagaa atagtggcag ttcattaggt agtatttgga aaatatttgc
    20881 tggaagtttt ctagctagcg gagtaactag aatcgtagga gctggctttg atctaatcaa
    20941 gggttccata agtggagcgg ttgatcgagt agatacgatg aataacgctc tacgaaattt
    21001 ccaaaatatg ggatttagta attcagaaat tatgaagaat atcggaaaga atgggctttt
    21061 atctcaaggt attcaaggac ttcctactgc tttgaatgat gcgataagtc atgttcaact
    21121 tcttgcttct tctacaggtg atttaactcg ttcaactcaa atatttaaag ctttaaatga
    21181 tggaattctt ggtttcggtg gttcaactga tcaagttaat gaagctgtta ttcaattatc
    21241 tcaaagtttc tcaaacggaa aagtagacgc acaaacttgg aactcaatga tcaacgctca
    21301 acttggacct actctttctg ctattgctaa aaagatggga attacaatgg gagatctgaa
    21361 agaaggttta tctcaaggta agatttctgt tgaagaattc caaaatcaat taatagaaat
    21421 ggataccaaa ggtggcggag gacttaaatc attaagtcaa atcgctaaag attctactaa
    21481 gggaattaaa acctctatac aaaatgcaaa aacagctgtt acacgtggtg ttggtgaggt
    21541 aatagaagga ttaaataaag cattagtaga ttcagattta ggtggattta agggaattat
    21601 tgataaagtg ggcagttcaa tggaatcgtt cttaaaagta attgctgcaa atattcctac
    21661 agcagtatca tttttaagta atttatttaa cgaaattcaa aaatttggtt ctgctttgaa
    21721 attcatgatg ccctttcttg ttcctgcagc taccgctttt ggagcgttca tgtttcaact
    21781 taaaggtata ccagcaataa taaaaagctt caataatttt aagaatgcca taattggcgt
    21841 tggaaattca ttaaagatta tgggggcaat agctgctgct aattcatttg ttttaattat
    21901 tggtgcagtc gttggtgcaa tagctgtttt cggttacttt atggcaacca atgaagagct
    21961 tagaaacaag gttatatcta tttggaatga tgtgaaagat tccgtaattg gtgtattaaa
    22021 aaatataaag gactggggaa ttgatacttg gaattctgct aaagaaatgg catcaaatgc
    22081 agttgagggt gtcaaagatg cttggtcagg aacaaaggaa tggttttcta acacctggaa
    22141 aggtattaag gatggggcca caggtttatt tgataaaaca gtagagactt caagaaatgc
    22201 agtcgatagt gtaaaaaatg catggtctaa tatgaagaaa tggttttctg atacttggca
    22261 aagtataaaa gattcagcca gagaaaaatg gaatggaatc aaaggttcta ttatgtcagt
    22321 tgctggtcca ttgattacag gtataaagaa tgcattttta catgttactt tttatctaga
    22381 gaccttatgg aataatttag ttgagattgg taaaaacgtc tttgagattt taaaaaatgt
    22441 tatacttgcg ccggttttgt ttattacctc catgatttct ggtggatggg aagaaacaaa
    22501 aaataatatg attgctgttt ggaataatat taaagaaagt gccataaata tttgggaatc
    22561 tataaagaat atatttgtaa gttattttac aaatatttat tttgctgcac tcaatatttg
    22621 gacagggttc aagcttacat tgataaatat ttggaatgaa gtggtaaatc aagctaaatc
    22681 gatttggtta aacataaagt atttttttat taatctttgg attgatataa aatattttgc
    22741 aattcagaaa tggattgaat tgaagttttc tattattcaa acttggatcg atttaaaata
    22801 taatgccatt actacttgga ataatattaa acagtttttc aaagatactt ggaaaaatat
    22861 taaagatacg gcatacaata cgtggatttc tataaaaaat accatgatta atacatggaa
    22921 taacattaag gactctttct ggaatattgt tactggaatt gttaattctg ctgaaaatgc
    22981 atggacaaat ctaaaaaatg gtgtttcaaa tgctattaat cgggtaaaag aaatctttaa
    23041 ttcgttaagg gaagtcaatt tatttgaaat tggcaagaac atcattgatg gacttataaa
    23101 tggtgtaaaa gaaaagtgga atgctttgaa agatactatc aaaggtattg caggtaatat
    23161 caaaaattgg attaaaggag ctttagatat tcattctcca tcaagatgga tgcgtgatat
    23221 ggttggtaaa aatattgttc aaggtattat cgttggtatt gataaagagc aaagtaagtt
    23281 agatcaaacc atgacaaatt tagtaaaaac accgtctgtt caacctgtag taaatggaat
    23341 aagtcaccta ccaattacac aaacaaagca aaatatatct gctagtgaaa caaaagaaat
    23401 tcatttacat ttaaatgttt atggagattt acctgattca atggttcgaa agattactac
    23461 aaaaattaaa acagaattga caagacaaat gaaacgagat gctggtgcag taggaggaac
    23521 attatatgca acttaagaga ggacaatttt ttattaatca acattattct tctgaattta
    23581 atgtgtatat tcaaaacagg cctgcttctg tttcagctag tcgagtaatt gaattgagag
    23641 agcgagaagg aaatgattct atcattattg ataaaggcta ttacaaaaat gtgactagaa
    23701 agattgagtg ttactataaa gcaccttcaa ttgatatggt gcaggagtgg gaagatcgaa
    23761 tcactgaatg gttagatatg tcgtcttata gtgattttat tctttactat gatgaacaat
    23821 atatttatca agctgtagta atagaaggac ctgaatttaa aggaacaaga aaaacaggaa
    23881 atattgtccc ttttgaattt acagtgagta ttcgaccatt taaggaaaat tacaatggta
    23941 gatttactat tcgacaaaca gaaacttttg aaatttataa cccagagaag tattcttcaa
    24001 aaccgcttat taaattgagt ggttctggag atgcttcttt ttatattaat aaggataaat
    24061 atgatttgaa atcgttggac agagaattat ttatagattc taaattagaa gaggcttatc
    24121 gaaaattaga tggtaattta gaacatcagg atcaggtcac cttattttta gattttccat
    24181 ttttatatcc tggaaaaaat gaaattaaat ggacgaaaaa tattcattca tttgaaataa
    24241 tgcctaggtg gtggagaaaa gtatgaaacc aagaatatat agtcctactg aaacagattt
    24301 ctcaacgaat ggcttaggaa ttttaaagga ttgtacaaga tgtgaaatat atgaagtagc
    24361 taatggaaaa tatgaattag agttggatta tcctttagga actagatttg atgaatattt
    24421 tgaaaatgac tatcaaataa aagcaaagcc aaacgatcaa gaagagtatc atatcttttt
    24481 tattgatgat aaagatatag atactttttt aaatacagta actatttatg ctcagagtcg
    24541 tacaaatcga cttggaagac gggtagtcac tcttgtggaa gtggactcta aaactggtca
    24601 agaagcgata tcaattattg aaactaaaat ggataaaaaa tctgacatac gactttattc
    24661 tgatattacg gctgtttcta gcacaatctt tgaagcgaga aatgttttaa attgtattgc
    24721 tggtgaacaa ggatcattgc ttcaatattg gggcggagaa attaaacgtg aaccatttaa
    24781 gctttctttg ttaaagcgaa gaggtcgcaa taatgttgga acgattcggt atggaaaaga
    24841 tatgtctggt ttgaaggtca aattagattg gacaggtata aaaacaagaa ttattccata
    24901 tgctgatcct caaagtgaag taggtacgac taatcgaatt tatggttcgc cagtagatag
    24961 tgcctatatt aataactatc ctgatgtcta tacagaacat gttcagttta cagaagaaca
    25021 aggagtaaaa gacattaaga gcttaaataa aatagctaaa aattacttta aaacgatcaa
    25081 tcctggctgt gataagccta aagtttctat tacggttgaa tttgataagt tgactgatag
    25141 tgaagaagcg aaagaatttg cgaagattag aaattatggt ctgtttgata catttaaaat
    25201 atatcataaa aaatataata tttatcttga atcaaaggtt agtggactac aatacgattc
    25261 tttatctgaa aaaactttga aattagaagc aggagacatt caagttgctt tttatcagca
    25321 acaagctgta actattcagg ataaattaaa agattatgca acgaataatt atatgagtga
    25381 ttttaatgat tatgtttctt caatgattac aggtcaaggc agtgcaggag gatatgtagt
    25441 tttatggcca aaagaaaaac cttccaacat ctttattatg gataatccag atttagaaaa
    25501 ggcaagagaa gtactaagaa tgaataaaaa tgggattgct ttttctaaga aaggatggcg
    25561 ggggcctttt aattcagctt ggacattaga tagtatattt aatgccaatt ttatacaaac
    25621 tggattaatc aaagcagata tctttcaaaa ttcttttaac aagactggag atgtattgaa
    25681 attagttaat ggactactcc aaatttggaa caacaaaaag aaaataatgg agttaactaa
    25741 aaaaggaatg gaattttgga attctaaggg ttcaattgga acgattggaa caactgattc
    25801 tgttggtaat ccttttcctg gggcttctac tccaacccct attgaagata attctttagt
    25861 tattcgtaca aatggagacg gcaaatatat tttgatttct cctaaagtag gaaaaggatt
    25921 agttttatta ggaaatggta aagcaattta ttttggagac ttagatgtac aaggaaaact
    25981 tacagttaaa ggaaaagaaa taattcctgg acaaggtggt ggtccatcgg gaggtggaga
    26041 atctactggt gggtatccta gtgaattaaa aacagatgca gaaaagagag cttggagaat
//
LOCUS       DAFLWC010000035        25983 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.036, whole genome shotgun sequence.
ACCESSION   DAFLWC010000035 DAFLWC010000000
VERSION     DAFLWC010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25983
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.036"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..627)
                     /locus_tag="L1V17_001363"
     CDS             complement(<1..627)
                     /locus_tag="L1V17_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1236142.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELID"
     gene            complement(638..1306)
                     /locus_tag="L1V17_001364"
     CDS             complement(638..1306)
                     /locus_tag="L1V17_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBN1236143.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(1436..2020)
                     /locus_tag="L1V17_001365"
     CDS             complement(1436..2020)
                     /locus_tag="L1V17_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1236144.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(2351..2584)
                     /locus_tag="L1V17_001366"
     CDS             complement(2351..2584)
                     /locus_tag="L1V17_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HBN1236145.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(2599..3549)
                     /locus_tag="L1V17_001367"
     CDS             complement(2599..3549)
                     /locus_tag="L1V17_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBN1236146.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(3546..4388)
                     /locus_tag="L1V17_001368"
     CDS             complement(3546..4388)
                     /locus_tag="L1V17_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBN1236147.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(4390..5109)
                     /locus_tag="L1V17_001369"
     CDS             complement(4390..5109)
                     /locus_tag="L1V17_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBN1236148.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
     gene            5801..5959
                     /locus_tag="L1V17_001370"
     CDS             5801..5959
                     /locus_tag="L1V17_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1236149.1"
                     /translation="MNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKD
                     FMNTFKIT"
     gene            6031..7257
                     /locus_tag="L1V17_001371"
     CDS             6031..7257
                     /locus_tag="L1V17_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1236150.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLL
                     TFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTV
                     IQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPDLVHLSPHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIV
                     DKAVFEAFQRGLNKCD"
     gene            complement(7345..7737)
                     /gene="rpsI"
                     /locus_tag="L1V17_001372"
     CDS             complement(7345..7737)
                     /gene="rpsI"
                     /locus_tag="L1V17_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBN1236151.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(7753..8196)
                     /gene="rplM"
                     /locus_tag="L1V17_001373"
     CDS             complement(7753..8196)
                     /gene="rplM"
                     /locus_tag="L1V17_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBN1236152.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(8715..9182)
                     /locus_tag="L1V17_001374"
     CDS             complement(8715..9182)
                     /locus_tag="L1V17_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HBN1236153.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(9302..10840)
                     /locus_tag="L1V17_001375"
     CDS             complement(9302..10840)
                     /locus_tag="L1V17_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HBN1236154.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            10920..11606
                     /locus_tag="L1V17_001376"
     CDS             10920..11606
                     /locus_tag="L1V17_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBN1236155.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(11807..12334)
                     /gene="msrA"
                     /locus_tag="L1V17_001377"
     CDS             complement(11807..12334)
                     /gene="msrA"
                     /locus_tag="L1V17_001377"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBN1236156.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(12418..13095)
                     /gene="pgmB"
                     /locus_tag="L1V17_001378"
     CDS             complement(12418..13095)
                     /gene="pgmB"
                     /locus_tag="L1V17_001378"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBN1236157.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(13092..14222)
                     /locus_tag="L1V17_001379"
     CDS             complement(13092..14222)
                     /locus_tag="L1V17_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBN1236158.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(14222..16405)
                     /locus_tag="L1V17_001380"
     CDS             complement(14222..16405)
                     /locus_tag="L1V17_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBN1236159.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(16402..17427)
                     /locus_tag="L1V17_001381"
     CDS             complement(16402..17427)
                     /locus_tag="L1V17_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1236160.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(17472..18299)
                     /locus_tag="L1V17_001382"
     CDS             complement(17472..18299)
                     /locus_tag="L1V17_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBN1236161.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(18296..19363)
                     /locus_tag="L1V17_001383"
     CDS             complement(18296..19363)
                     /locus_tag="L1V17_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HBN1236162.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(19389..20225)
                     /locus_tag="L1V17_001384"
     CDS             complement(19389..20225)
                     /locus_tag="L1V17_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1236163.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(20222..21091)
                     /locus_tag="L1V17_001385"
     CDS             complement(20222..21091)
                     /locus_tag="L1V17_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1236164.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(21161..22444)
                     /locus_tag="L1V17_001386"
     CDS             complement(21161..22444)
                     /locus_tag="L1V17_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBN1236165.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(22458..24143)
                     /locus_tag="L1V17_001387"
     CDS             complement(22458..24143)
                     /locus_tag="L1V17_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HBN1236166.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGTRVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            24418..25443
                     /locus_tag="L1V17_001388"
     CDS             24418..25443
                     /locus_tag="L1V17_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1236167.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
BASE COUNT         7792 a         5256 c         4374 g         8561 t
ORIGIN      
        1 atcaattaat tctttcaaat agtaaaaacg atgttcagct ataacaatag taaatccttt
       61 attttttaaa tcacaaagta agtcagcaag tttcttagtc gctttgaagt ccaaatttga
      121 agacggttca tccaatataa ttaatttaga gtttagcgat aaactacatc caatagaaat
      181 tttctgccgt tcaccacttg atagcgaaaa aatgttttta tctaatatat ttgaaagatc
      241 taataattca gctaattcat tgattctttt atccatatgc tcttttgtaa atccaaagtt
      301 ttccatcgaa aatactaact cactcgttgt atttgttgta aagaattgtc ctctaggatc
      361 ttgacttacg tagccaatat tttttgatat actttcttgt gttaaggatt gtagcgagtt
      421 attttcaaat aaaatttccc caaccaattt tccgtcataa agtcttggaa taagtccatt
      481 cattaacttt aatagtgtgg atttcccact cccagaagaa ccagtaatca atgtaagact
      541 gccttttttt attgaaaaat taaggtcaac aagcgcttgt tccttaacat ccttatatga
      601 aaaagaaaca ttgttaaatt caaacaattc tttcacctca aatcaaaata cttaagaaaa
      661 aaatagtaac ggaaaacagg atgatatagt ctaataagct catgtttgtt ttatagtaag
      721 aacttctttt cacaggagat tctatcccct ttgttattgc attagcggtc atttcttcag
      781 caatcatagt tgcacgtata agaacgggaa ctaacagaaa ttccaaatat tgcagaggct
      841 gaaaaaaaga caagcgaatg tttctcattt ttaaagattc tttaatcatt cttatttcag
      901 aacgataagt cggaaagaat ctgatcacta ctgtaatact taacattatt tttttcggta
      961 aatgtatttt ttctaaagag gataataatt cattgctagt atagacacta accaacaacc
     1021 atgagatcat tacgaccggc aacattcgaa atacaatata taaggatgtc gcaaaaaata
     1081 tagtaaaaaa ctctatcttg atagcatcaa taattttcat tactaaaaac agaactgaat
     1141 aaatcaagat gaaataaata catgtcttta ttttacgaaa catcaatact aaaactgtag
     1201 caataatgaa acaccccact tgaaatatat ttccctttcc taaaaaaata atgaccggaa
     1261 aaaaaatatt taaagtaatc aaggttaacg gattgatttt tgacactctt tcacctccaa
     1321 aaaataagat cgcactgtta tcttaagctg ataaaaatgc accgttattc agataacagt
     1381 gcgatcttat caaaaagcat aactgagaac aattctcaat gcaagctttt tttaattaac
     1441 tcagtaattc aatccaccca ggaacagaaa attgatacaa tcttctggtt aatagcatag
     1501 tcttttcttt tgaatagcta tgcttcaata tatcatagaa tgtagcgtag aatgagtaaa
     1561 tgtagaagtg gatttcttct tcattaaaga ctaaattttg attgatcatt ccgatagtct
     1621 ttaacttatc tagacaacag actgtctttt tcgtcacaaa tgatgtaatt ttttcaacaa
     1681 tatcttgata tttggttcca gctgattgga ataaaatcaa atcgaatata cgtttattct
     1741 caaaaatata attaataaat ggatctaatt cattgaagtt ctctctccaa cttttctcta
     1801 tatctatatt ttctaagttt aagaggtatt tggtaaactc ttcattatac atattaataa
     1861 gcgcattaat atgcggctga ataatttctt caaataacgc ttccttagaa gtaaaatgtt
     1921 tataaaaagc acccgtagtt acgcctgcgg tcaggcacag ttgccttatc ttagtttgct
     1981 gaaatccttc tttttcaaaa tggcttagtc cactttctat taacttttgg tgagttataa
     2041 tataatctct ggtttctatg ggtacttcct cctaataaga tgaattaact ttattatctt
     2101 acacaggact tgaagtttca atcgttaacg tttattactg aactcattcc ttagagctaa
     2161 actaatgaga aagagcagaa taactgatac aaaaagcaat cctacaagaa ttaatagact
     2221 catctaaatc attcaccttt tctaaaataa tccgagaaag atttaaaaaa attatatcca
     2281 gctattagga taagtcctat cataatcact ccaatagcca ttttcttatc ctccctaaaa
     2341 ataaagtctt ttacttaaaa ccttttttgt aatcgtcaat aaattttttc cctttatcag
     2401 ttaattgaaa tcctatatct aaatagtcct catatctaag tttagccagc atctcactta
     2461 cagatgctgg actaacactt agaacttttg ctaaatcatt attttttaat ttcttttttc
     2521 tttttgataa ttcctgaatt gctagtaaat aaattagtat agtagtcgtt ttaatttgta
     2581 ccatacctac cctccaaatt atttcgaaag gccttcagca attttatcca ggttccattt
     2641 catcatcgca tagtaactat caccatcttg tcctttttct gcaattgaat cagtaaaaat
     2701 cgttgaatag ataggaatat tggtatcttt tgatactgtt ttcattggtc tatcatccac
     2761 actgctttct acgaataagg agggaacttt tgttgtgcgt aatttttcaa ctaagtgttt
     2821 tatttgatct ggtgttcctt cttcttcagt gttgatttcc caaatgtaag cagaaggcac
     2881 attatacgct ttcgagaaat atttaaagca tccttcactt gtaacaatca tttttttatc
     2941 attcggaatt gaagcaaatt tagatttagc ttctttgtct agagaatcca atttttcaat
     3001 atacttatct agattttctt tatagaattt tttattatca ggatcttttt ccgctaactg
     3061 tttttcaata tttttagcgt aaataatacc gttttctaaa tttaaccaag catgaggatc
     3121 ttccttccct ttctcactct gaccctctaa gtaaataaca tctatgccat cacttgctgc
     3181 aaaatagtct ttgttttcct ctttgttcgc atttttaact aattttgtaa accaagcatt
     3241 tcctccagtt tccaagttaa caccgttata aaaaatcaaa tctgcttttg aagttttttg
     3301 aacatcttca ggcaaaggtt catattcgtg gggatctttc ccaataggta cgatactgtg
     3361 taaatcaatt ttatcttttg ctatattttc ggtaatatct gctaaaatcg aattagtaac
     3421 tactactttt aatttttcgt tcgaagccac tttatctttg tctttactat ttattgaaca
     3481 tgccccgaat ataaaaagag caatcaaaat ccccagactt cccagtactg ctttccattt
     3541 tctcatcata acgatctctc cttctttctt aaaaattttt gttttggtga gattagaaaa
     3601 ctaattacaa ataagaatgc cgctgttaaa acaatacttg atcctgctgc tatgttaaaa
     3661 ctataaccaa taaacaatcc aagcaatgat gaacttgctc cgactgttgc agaaataaat
     3721 atcatagttt tcaagctatt tgcatataaa tatgctgtag ctgctggtgt aattaacatt
     3781 gcaacaatta atatagttcc cacactttgc atagctgtta ctgctactaa agttaataga
     3841 accatcaata gataatgata aaaactgaca ttcatcccta ttgcttttgc cattaatgga
     3901 tcaaaagaag tgattaataa ttctttaaaa aatagaacta ctataaccaa cactaaaacc
     3961 gaaacgccaa ttgtaatcca cttatcaata tcttgtacag ctaaaatatt tccaaataaa
     4021 atatgaaata aatccgttga gctatttgca actcctataa ggataactcc tagtgctaaa
     4081 aaagaactga aagtaatacc aattgctgta tctcctttta ttacactatt gctttttata
     4141 aaagtaataa tgatagaagc taatagacca aatacaatcg caccaataaa aaaattaata
     4201 cctaaaatat aagaaattgc tactcctggc aaaacagcat gagaaatagc atcacccata
     4261 agagacattc ctcttaaaat aataaaacaa cctactgttc cagaaacaat ccctataact
     4321 acagatgtaa ttagagcatt ctgtaaaaag tgaaagtcat acagaccatt aataaaattt
     4381 tgaagcatat tattccccct ctccaataaa tatagtatct ccataggctt tttttaaatt
     4441 ttcttcatta aatacagatt ctacacttcc gtgagcaatt agatttcgat tcaaaagaat
     4501 aatattatca aaatacttct ttaccttgct taaatcatga tgcacaatta gcactgtttt
     4561 tccctgatgt ttcaattttt ttaacgtatc cataattatt cgttcactaa ctaagtctat
     4621 ccctacaaat ggttcatcta aaaatatgaa atccgcattt tgagcaagac atcttgctaa
     4681 aagtacacgt tgaaattgtc ctccagataa ttctcctatt tgatgattag aatattttcc
     4741 catatcgacc ttttccaaag cctttgaaac tctttgccat tctgcatttt taattctttg
     4801 aaaaactttc attccggcat atgttcccat agatacacat tcttttactt ttattggaaa
     4861 agtaaaatca atatcagctt tttgctctac atatgcaatc ttcaccagtt ttttattgat
     4921 atcttcatta ttaatggaga cctctccctg atgagggata atatttaaca ttgctttaag
     4981 caatgtggat tttccagcac catttggacc aataatacct gttaaagcac cttcttgtat
     5041 ttttaaagaa atctcgttca atgctaaaaa atcgttataa caaacattaa gctttttcac
     5101 ttctaacata actttctcct tctaaatgat aatgattatc acgatcatat ggtatacaaa
     5161 aattatattt tagtcaaccc taaattttat agtttagatt tttttctgtt gctgaagatt
     5221 agaatgacaa aactatttga aactacgcgt atagtaagta gctttcaaaa tatataaaaa
     5281 aggagcgttc tcaaatgaga acatgctcct aaaactactt tattggcgta tggaaaaatt
     5341 atacttgaag tggatagcgg gttgaataag ttgataagca tcaaaacatt tataaaaatt
     5401 attcaagact atgtctgttc catatacaaa tatgaaaatc agtaaactcc atttaacttt
     5461 tttcgtagtg tgtcttttta tacatgttta tcgttattaa tagtgaatag gaaaaaaact
     5521 atttttgatc attgacaatt aaatacaatt tttgaataac gatccctgct attcgagcta
     5581 gaaactcaag tacgccatga cctgattagc gacaaatact tagagatttc tttttgttct
     5641 gggaaaacaa aatgccatga caatagcagc aaataatgat acttccgtaa ggctcgccgt
     5701 aaactgggga gaggtgaaat tcctatgtgc ttacccaaag caattcaaaa atttcataac
     5761 tactatttta ggagatgatt ttatagaatc cagagtctac ctgaataaaa aacaaacctg
     5821 tgcatttcta ggaatcgata ataatactct agataagtgg attcgtatat ataatttccc
     5881 agtaataaga gttggtggtg tagttcgctt tgacgtagaa gatattaaag actttatgaa
     5941 tacatttaaa ataacttgaa attttcttct cgccgcatat actaaaatta gtgaaatata
     6001 ctgccttact ttttttaagg agtgaggatt ttgcctacaa agctttcaaa tgggaaatat
     6061 aaaactaatc tgagatatcc aaaaaggttt aaagaaataa caggaattgc atcagaaaag
     6121 tatcaaaaaa catttccaaa taggcaattg gcgattaaag ccgaaaatga tatgaagaag
     6181 aaaatagaaa aagttttgag agaggagaat gcaaactcat tagaattaaa aggaaaaata
     6241 acgtttaaaa aattttacga atctaaatgg cttcctagat atgaattagg tcaaacaatt
     6301 agatcaaaca ggcctcctag tgatataacc attagtaata caaaagatat atttcggttg
     6361 catattttac ctatgtttgg tgaatacgca atgaattatc taaatatcaa tactgagata
     6421 atatcagatg aattaaccaa aaaatcgaaa gaatatgcaa atataaaaat cataaaagga
     6481 tatgttcgtt ccatgttcga tattgcagaa atactaaatt atatcgaatt taatcgaact
     6541 actaaaatta ttcaaagtat cactgcacct aaaaaaaatg ctttagaaga aaaaagaata
     6601 caagaaggta agcaagcact atcatcaaaa gaacttacta attggataga agcagtaaat
     6661 gatgatttta ataatcattt acttactttt catgattaca cactttttat gattaccctg
     6721 tatcttggtg atagaaaaag tgagacttac gctttgcaat ggaaatatat tgattttgaa
     6781 aaacaaacgg tccgtcttaa acatacttta gataaatatc aaagaaaaaa gtttacaaaa
     6841 ggtcgaaaag ataccgtcat tcaagtacca gaagttgtaa tgacattgct aagtgaatgg
     6901 aaatcggtac aagctgatca attgttgaaa ttaaaaatta agcaaacgtt agatcagtat
     6961 ctctttactt atactaaacc atctggagaa gtaaattgtc ctgttcatgc cgattaccta
     7021 aactatcgaa tcaattcaat taaaagaagg catcctgact tagttcattt atctccacac
     7081 aaactccgtc atacttatgc aactatagct agacaaggtg gagcagatat gaatcaaatt
     7141 tcaaatgctt taacacactc agatatttct acaacaaaga tatatgtgaa cacaccagat
     7201 atagttgata aggctgtttt tgaagctttt cagagaggat tgaataagtg tgattgatat
     7261 gtgttcttaa atgtgttctt aaaaacaaaa gaagcacttt ccaaataatt gaaaagtgcc
     7321 agaaacgttg atatataaag gatattaacg ttttgagaat tgtgaagctt tacgtgcttt
     7381 cttaagacct ggttttttac gttcgaccat acgtgcgtca cgagtaagta agccagcacg
     7441 tttaagagct aaacggaagt caggatcaac ttctagcaat gcacgagcga taccatgacg
     7501 gatagctcct gattgtccag cgtatcctcc gccgtttacg ttaacaaata cgtcatatgc
     7561 gccttttgtt tcagtaacag cgaaaggttg attgattact tcacgcaagt cagcatgtgg
     7621 aatgtattct tcaacatctt ttttatttac agtaattttg ccagttcctg gtactagacg
     7681 tacgcgagca actgcgtttt tacgacggcc tgtgccgata tattgaactt gtgccaatga
     7741 aattccctcc tattagatta agtttgtgat gtctaaaact tctggttgtt gtgctgcatg
     7801 tggatgttct gctccaccgt atacgttcaa ttttgtaaat tgtttgcggc ctaaagtgtt
     7861 tttaggaagc atacctttta cagaagtttc gatcaaacga cgagaatttt tagcacgcaa
     7921 ttcgccagca gtgattgatt tcaatcctcc tgggtagttg ctgtgacggt aataaatttt
     7981 gtcagtcgct tttttacctg ttaatttcac tttgtctgca ttgatgacga tgacgaaatc
     8041 gccagtatcc aaatgaggtg tgaaagttgg tttattttta ccacgtagta cagatgcaac
     8101 aactgttgaa agacgtccca atggaacatc agttgcgtct actacatacc atttacgttc
     8161 tacttcgcct ggtttggcca tatatgttgt acgcacgtta ttttcctcca atttaagttc
     8221 tgatgtttga catacacttc gagtttccgg ggctctttgt ggggcaaaca ataccattta
     8281 acatattacc cgctaatcta gtcaatgtca acgtttttct gcttgattga aaaatttata
     8341 tgaaacttta cttcttttct ttcttttata taaaagggtc gtttcctgtc aaaatgaaaa
     8401 acaaaaagag gctgtgacaa aagtcttgtc acaacccctt attttgaata aacggtgttc
     8461 tcctgccaac tcctcggtca caagtcacaa tatccataaa acataagaag ctgtttttta
     8521 aaattgtttc ttgtgactcg gagctgaacg gcaggcttac aacctcttgg taaacggtgt
     8581 tcaatcagct gaccctcggt attagctcaa aaaacggcaa aatatgagga actattttga
     8641 cgtttgtttc tctaatactc aggtcaaaac gctgatttca caacctcttt ttcggtcaag
     8701 ttcaacaaca gtttttacgc gtcgatctct ggcgctttgc ccaaatgagc ttggatcatc
     8761 cagatacgtt tttctgtggc tgttttgaat tcgataaaga tatcttgtgt tggatcgtcg
     8821 ccttcttctc cagaaacttc gattcctttt tggtaaagat ctgctagata acgatagcct
     8881 gcaacaagtg tttccaaacg ttctggaata gtacgatccc agcggccaat ttcatcaggg
     8941 atttttgtgt tatctgcaaa ttcacgcaat gtagaataag gtgaaccgtc taatgtgatc
     9001 aagcgttcgg atacttcatc taactgagcg ttcaaatcat ccatgaactc atccatcatt
     9061 gggtgcaatg taaggaaacc tggtcctctc atgtaccaat gtgtttggtg aacaacaaca
     9121 gacatttggc ttagatctgc aactaattga tttaatactt ctttggtttg ttggaatttc
     9181 atctttcttg cctcctaaca ttttcttaca cttaaaataa tagtagactt tcaatgaaaa
     9241 gtacaacaaa atcatttacc tgagaacgat tttcagttcg cttttttatc cgtaaagcca
     9301 atcatttttc agaatcagct aattcttctc gcagttgagc aaattgctga taagtctgtg
     9361 ctaaatgctt ttgtgtcgaa acaaataatg gatagatttt ctgatatttt ttatgatcag
     9421 tttcttgtac tccaacttgc tctttcaatt ctatcaattc ctgtgcttca ctgatacttt
     9481 ggatctttcc gatgcttctc cagcctaaaa tcacagctcc taatgcggat gcttctgtga
     9541 cagtagggaa aacaagcggg taacccagta catcagccat catctgacga aaaatcggag
     9601 attgagcaaa cccgcctgta gcacggatct ctgtgagctg attttcctgg caaactcctt
     9661 ttaaaatccg ataaaggttg agacagatcc cttctagaat cgccttcatc atttcttttt
     9721 ctgtatgttg ccgctgtaaa ccgataaaac tgccaaacgc atctgcgtcc caaagcggtg
     9781 ctcgctcacc aagtaaatag ggatgaaaaa tcagaccatt ggcacccgct ggcacaaaag
     9841 cgatagccga aagcagtgca tcatatggat tttctccttt ttctttagca gattgaacga
     9901 cttcctgtaa aaatgtatgc cctgcccaat caaagatgcc agcaccattg ctagtcgctc
     9961 ctcccactac ccaatgtttc tgatccagaa cataacaaaa cgtctccatt tctggatgga
    10021 actgaggctg agtagtaata aaacgaagtg ctccgctcgt tcctacggtc aaagcggcga
    10081 tcgtatcacc aaaagcacct aaccctagat tagaaagcgg cccgtctgcc cctcccaaaa
    10141 caaatgatat atcatttggc aaacctagtt ctgctgctgt ttttgatggt agacctgtta
    10201 cttgataggt ggaaggaaag acttgcggca attgctctat tcgaatgttc aagtagtcaa
    10261 gcacttcttc tgcccattgg aattcatgga tatcaaaata tccagttcct gaagctgttc
    10321 cgtagtcgct gatcagttcg ccaaacaatc tataaaagat atagtctttg ataccgacaa
    10381 aataagcagt ttttttgaat aattcaggtt ggctgttttg cagccacttg attttgttca
    10441 atggtgtcat tggatgaatc ggcgtcccag tctgccgata aaattctttg ccaagcacgg
    10501 tatatttcag tttttctgct tcgtccgctg ctcggttatc tgcccaagtg atcattcgag
    10561 ataacggtgt tttctcttca tccaacaata tcaggccatg catcgcagag gagaaggaga
    10621 caaattgaat gattgtgtct gaaggcaact gtttaattac ttcttttata acggtgcaga
    10681 caccttgaaa gatcaattcc tgatcttgtt ctgccatccc ttgtgtttct tggatcaaag
    10741 ggtagcgaaa ataagcggat gctgcttctt gggcttcatc tgtgaaagca actgctttgg
    10801 tttgtgtggt tccgatatct aatccgattg aaacgttcat tttttcacct caaattttat
    10861 gtatgtacaa aaatttagtt taagcttgcg tatcttggtt ttgaaaaggg ggagatggcg
    10921 tgttacttta ttttatcatt ggttgctgta tcggatcatt tttatgttta accgcccagc
    10981 ggattccgtt aggtcactct attatttatc ctagatctca ttgtgtcaaa tgctgtcgtt
    11041 cgctttcttg gtatgaattg attccgattc tctcgatcat cgtccaacga tttcgctgcc
    11101 gctattgcag gtgtcggttg cccttctact atttgttggc agaagcctta tgtggtggtc
    11161 tttttgcctg gttctttact ttttcttccg caagaaattt ttcgacgttc atatggatgc
    11221 tttcggcttt gctattttcg ttgatggatt tattttactt catggtccat tctcacacgc
    11281 tattctgttc ttgggcaatt ttatggattt tttggttgca ggccggcgtc ttccaatggc
    11341 aaagtgtgct gttaacgttt atcgtaggcg gtgtgtgcct tcgctatggt caatcctatc
    11401 tcggagctgg cgatactctg ttgatgcttt cttggagtgg tggcttgtct ctagaagagt
    11461 tgcttcagat cttgtttctt gctagtctgt ttggaatatc cgttttttct gtttacttta
    11521 tctgtcataa aaaaaagttg gaaaagctgc ctttcattcc ttttttgagc agtgcgttgc
    11581 tgattgtcct tcatcttagg tattgaaaaa aggttgtgac aaacgacttg tcacaacctc
    11641 tgatatatag tgttctctta ccaaatcctt gtgacttgga gctaggcgac aggttcacaa
    11701 cctctccact aaatggtgtt caatcagctg accctcagta ttagctcaaa atgctggttt
    11761 tacaacctct gatatacggt gttccataag tagctttttc ggcttcttat ttcttgacgc
    11821 cccaatgtcg acgaaggaaa cctgcacgtc cagaaccttc tcgataaaga ttgtaatgga
    11881 gcttgttttt cttgtaataa tcctgatggt aatcttctgc aggataaaat tcgcttcttg
    11941 gttcgatttt tgtcacgatt ggcttatcga atcgcccgct gtcttgcaat gcttgttttg
    12001 aacgctctgc aatatttcgt tcttcttcat cattatagta gatcactgga cgataagaat
    12061 caccgcgatc agcgaactgt cctaatgcgt cagtcggatc ggtttgctgc caatagattt
    12121 ccaccaactg atcataagaa ataacttctg gatcatattc gatctctact gcttctgtat
    12181 gccctgttgt gcctgttgtt acttgttcat aagttggatt tggtacatgc ccgccagtat
    12241 aaccggatgt cacagaaatg atccctggct gctcttcaaa tggtttgacc atacaccaaa
    12301 agcatccgcc tgcgaaaact gctttttttg tcatataaaa tccccctttt ttctcatcat
    12361 accttgattt ccaaaaggag gataacgttt tgcttgtgac agaaaaaacg gaaactatta
    12421 tatacgtgat acggcttctg ataaatgcca aaacgaacgt acttgatcaa aaacggttaa
    12481 atcaggaatc acatattcag cagaaggaag atttatgttt tcacctattc ccaatacatg
    12541 catgttacca gccaaagctg cttgacaacc agcttctgaa tcttcaatga ccaagcatgc
    12601 atttggcggt acattcaatt gctgtgctcc tttgagaaaa acttctggat caggttttgc
    12661 ttttgatact tgcgtgccgt caataaggac atcaaaataa cttgtcaaat tcgttttttc
    12721 taaaatgagg cgtgcatttt tgcttgctga tcccaatccg atcttgatgt ttgttttttt
    12781 caagtactca agaacagcta ttgcaccagg caaaacggat gtttcatcca ttttttgaat
    12841 cgcttgaaga tatagattgt ttttttgctc agcaaaggct gatttctctt tttctgagaa
    12901 tttctgttcc atttttccaa atgacagcaa tcgctctagt gactcggttc tggatattcc
    12961 tttcagttgc tcgttttctt tctcagtgaa tggaatggac agctggttag ctaaaaccag
    13021 ccacgcttcg taatgataac gagctgtgtc tacaagaacg ccatctaaat cgaatagtgc
    13081 tgctttgatt ttcatcgatt acctccttga aaatgaacga cttgaagtaa agatgcgatg
    13141 tttttagctg tgcgatgaag attatcagtg gcttgctgta aagcttcttg taaaggcaca
    13201 gctgcaggaa ggatcggaaa aacggccgaa atgccaacat ctgctgcttt ttcgcttcct
    13261 ttaccaacac ttccgcaaat agctatcaca ggaacgccct ctggtactct tctagcaatc
    13321 ccaactggcg cttttccttt tagactttgt ccatctagac gtccttcgcc tacgattacg
    13381 aggtctgctt gctgtacccg tttatcgaac tccagtaaat ccaatacgta gtcgatgcca
    13441 gagactattt tccctgaagc aaatgctaac agtcctgcac ccattccacc accagcacta
    13501 ctgcccgatg cctcgattac ttgaggggca aatctcatat aaaaatcatg catggcttgg
    13561 tcagccactg ctaattcatt ttctttcaag cctttttgtg gtccgaaaac aaaagaagcg
    13621 ccttcttttc cgcataaaag attagtaaca tcagtaatga cagtgatttt ggctttaatc
    13681 agctcaatag gcacgttcgt tttatcaact gtagcaattt tacctagatt ttctcccagt
    13741 gcttctactt tttgattatc ttgatcgtaa aaagcataac ctagaccttc tgccatgccg
    13801 atgccgccat cgttggtact acttccgcca acgccgatga tgatgtgtcg aacaccttgt
    13861 tgcaacaatt gtcgtatcag ttctcctact cctcgcgtgg ataacctaag tggctgttgt
    13921 tggtttagtg ggacatcttt caatccgacg atttctgcca tttcaaaaat cgcagtttga
    13981 ccgtctgaag cgtactggat ttctttgttt ttgccaaatg cattagtaac gactgctgtt
    14041 tgccgcttca accttaaact gtctgctaat gatgaaaccg ttccttctcc tccatcgcct
    14101 ataggtagca gatcatattc agcctgaaca aaaacttctt gaaaacctga ttgaatggct
    14161 tgtgctgcct ctaaggctgt cagactttct ttgaaagaat ctggcgcaat cagaatacgc
    14221 attattttcc cctccgttcc aagatcagtt ctttttccag ctggtattgg tctccattga
    14281 caaaaatagg taatgtttct ttcgtctctt tttttattac tatttgtttt tttgtcaaaa
    14341 caaatagcaa cctgtgattt ttccaaataa aaggaaaaga aattttttcc catgctgaag
    14401 gaagtcttgg agaaatagaa agagttccat tcgttactgt aatacctgaa aaaccaaata
    14461 taactgctag ccatagtgct cctaatgaag cagcatgaat tccgtcatct gatgaatgcg
    14521 gatctggtcc taaatcaatc aggcacgctt cttggaataa atgatacgcc cattccattt
    14581 cttggatacg gcaagcctct atggcgtgaa tcgctttact caacgatgag tcgtggattg
    14641 ttttgttttc atagtaatgc aaattcttag aaacgattgg ttgagaaaaa tactcaggta
    14701 ataagtataa cagcatgaca agatctgctt gcttgctgac ttggagttca tttacttcgc
    14761 tacgggcata atcaagtaaa atagactggc tgccaggacg ttctttgtaa gtggtcaaat
    14821 caataactgg cttactgaga tacgtgtcat cttgcggaat cagctgttct ttgttaggca
    14881 ctggcaaata taacttatct aaaaaatttt gacattcttt caaaaaaagc ggatcgccag
    14941 cttgatattt aacagctaag gccacattat aatgcgccag atagttcgta tatgcattat
    15001 tgtcgatata ttctgtgtat tcatctggac caatgactct gtgtatctct aaatgatcat
    15061 cgacttttac agctctgctc agccaaaaag ctgctgtttc atgaatgagc gtttttccct
    15121 ttgtttctaa aaacgattga tcctctgttg cttggacata ctcttgaacg gcataagcaa
    15181 ggtctgcact gatatgatgt tctgcggcag ctgaagcaac ttcttgtctt gttccggttt
    15241 tgatattcaa tgcagcaaat ttgggtgtct cttcctgacc agtgtgtgcg ctttcccatg
    15301 ggaaaagtgc accttgatag tgataatctc ttgctttttg ccgtgcgcct tctaatcgat
    15361 cataacggta cagcagcaaa ttctttgcta cttcaggaaa ctgatataaa aagaaaggca
    15421 ggataaaaat ttccgtatcc cagaaaacat gccctttata accttcgcca gttagtccct
    15481 tcgcccctac actaacactt ggatcattgc ggggagtcat aatctgtaaa tggtaagcag
    15541 cgaagtccat cgctaactga tcgaaagaag aatcgccttg gatcgttatc cgatgctgat
    15601 gccaaaaatc tgtccaataa gacatcgact gctctaaaat ttctgtataa ctaacgcttt
    15661 tctgggcttg ggcaatactt ttcttaaacg ggtctgtttg ctgaagagag gtagagagca
    15721 cgatgatctt ctccagcgta aaggacgtat tttttctgat cttttctgaa aaggaagcgg
    15781 tgatccggcg attttttgct tggaatacac ctgctttatt gaatttagct gcaatcccaa
    15841 tatcaatttt actttctgtt gtctggtagg atgcactgat caaatcgtca ccaaatactc
    15901 gcagttcttt ttcaaccaac tgctgtgtac caaaattggt ttgctgtcca tcgatacccg
    15961 ttttcacatc tacttggcag tcttcggtca acggcttgat gaccactttc agggctgcct
    16021 gatggagatt attttgatca gcaacacgac aagtaatgac ttccactttt tttccttgag
    16081 cagtttcaat gagcgcatag cgtttaagct ctcccatttc taaatctagt gcccgctcgt
    16141 atgcaagaac tttcatcgtc tcaagagaaa aatgttcacc gtcgattttt atttcccatc
    16201 tgatgacatc tgggagattc actaactcgg ctgattctgc tcctaaaggt cggttatata
    16261 caccagctgc aaacattccc cttacttgat tccgatagtc ttcctcctgg cttcctctga
    16321 taccaaaaaa tccatttcca atggtcatct gactcgcata cttattgata tactctaaat
    16381 caaactgttt ttcttctact ttcataaggt aataacttct cctgtttctg ccgaacgata
    16441 taaattttcc accagattct ggatgacata tccttgccag ccatctgcaa tcatctgagt
    16501 ctggtcaccg agcgcccgat tcacaaaatg agccatactt agttcatgtg ggtcattaac
    16561 tggcgtggtc ttttgtaagg aaaccagctt tccatctaca tcttcgaata gttcgcctgg
    16621 atacagatta gcacctgcct gatcgccaca aaaagccaca ttcagtttgt cttctctgat
    16681 attcaaagca aacgaagtat tcagttggat gatcttgccg ttttctaatt ccagtgtgcc
    16741 aaaaattgca tcttctactg tgaatttgct tggatcccat ttcccgaatt tccctgaatt
    16801 ttttttcgta ccaatttttt ggaagctgta cgcccgaacg ctttttactt taggaaatcc
    16861 agtaatatac atcgctgtat caagcatgtg aatgccataa tcgatcaaag gcccgcctcc
    16921 ttgaagttct ttgtcgataa acgttcccca gcctggaaca ccagaccgac gaagcgcatt
    16981 cgcttctacg taataaatat ccccgagaac atcaagatga ttcttgatca ttgttgcttc
    17041 gtcagaaaaa cgatgctgga atccataagc caaaatctgc ccgtttttat cggctgtctc
    17101 tgccatcttt cttgcttgat cagctgtcat agctggtggt ttctcgcaca tcactgaagc
    17161 attagcttcg agggcagcca atacatgttc gaagtgaaag cgattgggtg tacagacact
    17221 cacgatatcg ggagaaatct cattcagcat ttgtgtaact gatgtatacg catgagaaaa
    17281 tcctgtacgt cggcaaaagt cttctgctcg ctggctgact ggatcaacca cagcggccaa
    17341 ttctaagaca tctgatcttt tttgataata agcagcatgt actttttctg ctacttgtcc
    17401 agcgcctatg attgctactt tcttcattta tttctccctc ctttgcttat ttacttattg
    17461 ttattctttc tctattcttt ctctaaatca tttaaatgac gcgctgtttc cagacagttt
    17521 ttcaagtatt gcaatgattc ctgataaatt ttcacttcat tttctcctcg caaacgacat
    17581 tcatatacca tataaccttc atactcattt tgaagtagcg tttgaaaatg gcgagtaaaa
    17641 tcaattgcgc cagatcctgg ttggtagcga tgattatctg ctaaatggat atgacccaca
    17701 tactcttttt gcgtagtcaa tgcttttgaa atatcatctt cttcaatatt catatgataa
    17761 aaatcagcga tgatctgcac atgtttcaat tgattagagt caatgtaatg acgcgcatcc
    17821 gctaacaaat tgatcatatg gtcttggtat cggttcaaag gctccaaata aataaccgta
    17881 cctgtttctt cggctacttt atctaaataa cgaagtgatt cgctgactgc tttatagtct
    17941 ccttctttgc ttcggggtga aaccatcggc ggtaatcgat aagtgaacat tccccaagct
    18001 gctgggataa cgattccttt gcctccaacc tcgcttagtg cacgcaaaat ctcagcaatt
    18061 tgacgtacac cattaagacg ccgttcttcg ataaagtcac cgatccaccc atcgtagccg
    18121 ttacaagctg tcactactgg gatccctgtt tctttgattg cctgtttgac tgtgtcgata
    18181 ttttctatta acaacttacc gtcgatttcg tattcttcaa atccacagtc tttgataaat
    18241 ctaaattttt ctaaaatgtc tcttgggaaa aatgcttgat cttgcgtacc gaatttcatt
    18301 gttctcctcc tcggacttga acgcccattt tgatactttc ttctgggtgc tggtctacat
    18361 aacgcatgta agcttctgcg ctttctgcaa atggcacaac tggatcaatg atttcttcac
    18421 aatccaagta accgttcatc aataattccc aacatgtgtc ctcgattcgt ttacggttcc
    18481 atcttgggta atctgggttt ggttcactag atgctcgagc aaagacgatt tttgcattat
    18541 tgaaatgtgc ttcgcgacca agattaaacc cagctggaaa aggtttagca aaggcaacat
    18601 aagaaatgat cccgccatag ccgatccctc ttaaagaagc ttgtaatgcg gcagcactgc
    18661 cactcgtttc aataactgaa tctactccac gtttatctgt caattccttt agacgaaaac
    18721 cgacatctgc tttcatagga tctagcgtgt aatcggcacc gtatttttct gctaattctc
    18781 tacgctgcgc tatgggatcg atcccaacga tggtagtagc acctgctttt ttagctaatt
    18841 gaatcgcaat ttgcccgata gcgcctaaac cgaagattgc tacagcatca cctgctcgaa
    18901 catgtgcttc ccggatacca cctaaagcga attgagcagg atcgtaacat actgcatttt
    18961 tccattgatc caaccgatca agtttacgta gtttataatt atcaacaccg tttgtaatca
    19021 gcgtttcacg aatgggtcca taagtgcaga ctaactctcc tttttgatac tctgtcacca
    19081 aactgcccgt ttcttcgatc gtaccgacaa tcatatttcc taattgaaat tcgccaaata
    19141 ccacaccgcg ttggcttcct tcttctcttg gcaagaatag gcgccattct tctgaaaatt
    19201 cttcatcgat aaatggactt aatcctctaa agtcgacaat ttctgttcct ggttttggag
    19261 tagcgaaaat tactcggata cgtacttcgt tcttttcgat ctcacggtct tcgtaatctt
    19321 tgaatccggc tattcttggt tctaatgcaa ctaatttttt catcttttct ttcctctttc
    19381 ttttcttttt atccttttac gccgccttcg actaaatcac ctttaataaa tcgttcagat
    19441 aacgcataca taatgatgac tggtaaagcg gtcaccaatg aagcggccat cattcgtccc
    19501 caaatgtagt ctggtgtact gaataatgtg ttcaaaccga ttggtaaagt aaatttttcg
    19561 gaggtcgaca ggaaaatcga agcaaataaa taatcattcc acgaaaccat aaagcaataa
    19621 acgaagacag aaatgattcc agaaatagcc aatggtataa tgatccgaat aatgatctgg
    19681 atccggctaa gaccatcgat cattgctgct tcttcaatat cagtcggaat cgtgtcaaaa
    19741 taacttttta gcatgaatat cgcagtagga agtgtttgaa cgaccatcgt gataatcagt
    19801 gctgtattgg tatcatacaa acctagaccg gaaatgattt taaataatgg aacaacgatc
    19861 aaaataccgg aaaacatata aacggtgtaa aagctagcat tgattttcga gcgagctttg
    19921 aagcgtagtt ttgacaaagc gtatgccccg ctgatcccaa tcactactgc agttacggag
    19981 gctatcaagg agatcactaa actatttttg aaatacatga tgaatggaaa aatctcagca
    20041 ttgaaaatat cctgataatg ttcaaaagtc cattctttcg gaaaaatagt ttgtgtcgtt
    20101 gcaattgctt cttgtgaatc cttgaatgat gtcatcagca tgatcaaaaa tggaaacaaa
    20161 ttgacagcta atagcaacaa aatcgtcgcg taaaataaga ttttcctgct ctttttattt
    20221 ttcatttcaa gtccaccttc tttcgtgaga gcaagacgac cgctgcaata atgatgaaca
    20281 atagaatcga tatagctgct gcttttccaa gatcattgaa cgcaaaggct gtctgataca
    20341 aataaacgcc taagatattg actttattcg tcagtagata gacatctgta aacatataga
    20401 acatccagat agatcgtaaa acaatcacag ttgctagtac tggtttgatt gccggcagtg
    20461 tcacgatctt gaacttctgc caagcatttg caccgtccat ttcagctgct tcataaagcg
    20521 ttttgtcgac tgtttgcaaa atagccaaaa atgaaataaa cgcatacgga tagtatctcc
    20581 agatagcaaa caaaacgacc ataaagaagc tagcaactgg ctggtcgaac cacagcggtg
    20641 cttcgttgaa aagctgcaac ctatctacta acagatcatt gacgattcca taactattat
    20701 tgaacatata tttccaagca aaaatcaaag aaatagatgg cgtaacataa cttaataaaa
    20761 tcagtgaacg caccgttttc ctaaatctga acttgcggtt aagcaaaata gctacggcta
    20821 atcctaaagc tgtactgcct gctacaacta agaatgtgta agcaactgtt aaacctaaag
    20881 aacgataaaa ttcactatca cttaaaattt caagataatt gcttaatccg ataaaaacgg
    20941 cgtctgagtt aggattcagc ggcatatcga aaaaactgat ctgaatattg gaaagcattg
    21001 gaatcagcac taaaacagct aataaaagca tgcttggtgc taaaagtccc atggctaatt
    21061 ttaagtcaga atgtttcctt ggacgattca ttgaaacctc cccctgataa tctgccaata
    21121 gctatctact tttttcgaac accattggca gaacttcttg ttatttcgta tttttttgtg
    21181 cgtcagctaa agcttgatcg acatcttcgt ttccgacagt tacttggttc actgcttttc
    21241 cgatcacacc tgagcttgtg atatctccca ttttcgtgaa attcttttcc ccgactagtc
    21301 caaagacttg tacttcatca aaagcactag caatctcaga tggcagctcg ccaaaagact
    21361 tgatgacttc attttctttg taaccatcca gttcgactac ttgtttattc actggttgag
    21421 caccaccagg agacatcaag acccactttt ccatgttttt cggttgagat aagaaagctg
    21481 tgaatgcttc agcagcctct ttttgtttct cgtctagacc agaagaaatc gtcaatccag
    21541 atactgtgcc atagacagct tgatcttttt gtgttgggat agcaaaaccg atattttctg
    21601 agttccccgc ttcataaaca gaaggcaaaa tgtaagttga atagattgcc attggtgctg
    21661 ttccattcat gaaagcatct ttgatttctg tcacatcatt agagcctggc atcgtgtatt
    21721 gggataagtt ttgataaaac gacaatgctt ctctcatctt ttccgtatcg atcgttacct
    21781 cgccttcatc atccaaaaca tttgctccat ttgacaaagc aaattgagag aacgcttgct
    21841 cactcattgt tccttcagca gtaggcatag caattccata ttgtttattc tctttatctg
    21901 tgaaatgttg agcaattttt aaaatatcat cccaattttc tggttctgaa aaaccagctt
    21961 ctgataattt ttctttgtca taccaaatac cttgaaccca gccgctaatt ggtgcagcaa
    22021 tatagctttt tccatcttct gaacgaacaa ggtttttggc tccgtcataa taattatctt
    22081 ctccagcttc ctcgataacg ttttggactg ccgtctgatc aatcagttca tctttatcca
    22141 tcactttagc aaaatcctga ctgacttcca ttacttctgg taatttaccg gaacgagcta
    22201 acgtaacgat ttttgtattg aacgctgatt cttctaccgg cacttgcttg attttgatgt
    22261 ctggattttc tttttcaaaa tcagcaacca gttcattgat cacacttaat cgttcctgtt
    22321 cgacagaaga gtgcatgaat tgaatcgttg tctgttgtga ttcgttagag ctttgacttt
    22381 caccacaagc agtaagaaga aatccagtag ctagcagaca ggtagtaaca ataatttttt
    22441 tcattttttt ccacctctta ttttattatt ttcagccaca tatattcata cggctggaat
    22501 atcaactttc gttcttgact gcaatggata atttgtccag aaaacaggtc taggtaatct
    22561 ccttttggta aaagataacc tgctgattga ttggaaaaat tatggataac taagactttc
    22621 tcttccttcg cttcgcgaat aaaactgata aaagaatctg ctgagtccag taagtaaatc
    22681 aaactattcg gatggaaggc tttttctttt tttcgaatag atagcatctg ggtcaattca
    22741 ccatatactg ctgttcttaa tggatctgtc tgcaactctt tctcaatatc tgctaacaaa
    22801 aatttttgcc gattgatttt tcgattctct cctgtttttt ctacgccttt gtaatcattt
    22861 cgacttccca gcacactttg aatataaatt gccggcacgc ctggtaacgt taccaaaaat
    22921 gaatgagcag ctaaaaagcg tttgcttctc cattccgtcg tatctgttgg agaacttaac
    22981 gcatctagat acgtagcgtt tatctcatat ggactggtcg ttccatctgg gtttttcttg
    23041 tagtttactc gggtaccctc tttcttcagc tgttccacta attcaaggat cgttttttcc
    23101 ggcagaatac ctcgtaccgg attcaatccg ataccgtcat gggaggctaa aaaattaaaa
    23161 aaagttgttt ttttcgatgc gaaatcgatg gtttttaacc attctttcaa cttacttgta
    23221 ttacccgaac gaatcgcttg aagggtcaaa ggtggtagcg aaaactgata gaccatctgt
    23281 gcttcattct cgccattccc aaaataactg atattatctt tgtgtggcac atttgtctca
    23341 gtgatcaata ccgttcctgg agctgcttca tcagcgattg cacggaataa ttggatgatt
    23401 ttatgcgttt ctggcaggtg tatacaagaa gttcctagtt ctttccataa aaatcccaca
    23461 gcgtccaagc gaataaatga agcgcctttt tctaagtaaa acaaaagaat atcgatcatt
    23521 ttcaataaaa cttctggatt tttaaaattc aagtctactt gatcttcgct aaaagtcgtc
    23581 catacgtgtt tttctttccc gtttttgtca atgaacgttg taagtaacgg gctggtcctt
    23641 ggtctagtca cgctgcttgt atctgtatcc agtggcaaat caataaaaaa atctttgtac
    23701 gtatcattca agtttaaata ttcctgaaac caagtacttt cggcagacat atgattgcag
    23761 acaaagtcga acattaaccg tgtttcgctt ctcatttctt ctatatcttc ccatgtgccc
    23821 aaacggtcgt tgattgcctg ataatttaca acggagaaac catcatcaga tgtatatggg
    23881 aaaaatggca agaaatgtac aactctaaat gtatctgcca aatacttttg ataaaatttc
    23941 ttaaatgtac gcaaagttgg ttgctgctct tcaaaaaatt gatccccata agtaatcaag
    24001 aaaatatctt cttcgtccca atgcagtttg cctgcctggc ctttcttctg ctgataaaca
    24061 ctgacttttt gttcaatcat agaggcggtt ttctcagaca aatctgagtc gcgataaatc
    24121 gcttgtaaaa gttttgtata catcggattc ccctttcttt tttgggagcg ttcccaacga
    24181 tttgatcata ttatggaaaa cgcttactgt caatagcatt tttttaaata attttgatat
    24241 acacaaaaat acaaataaga aagcttatgt atcaataatt aatagcttct taaaaaaata
    24301 tggtctctca tgatcatgca agctattcct aaattttcaa aatcatagac aaaaaagaat
    24361 gtctattgta ctatggaatt attctaaaac gctcccaaaa aggaggtgca tataaaattg
    24421 aaacctacta tttatgacat tgcgaaaaaa gctaatgtct caaaatcaac tgtctccaga
    24481 gtattaaata accagccaaa tatctctgat aaagcaaaag caagtgtact tcaagcaatc
    24541 aaagaattga attatgaacc gagcaaaatt gcaagaggac tgtcaggaaa tggttttgac
    24601 gcgattctag cattatctca tcgtacttct catacgacct atggcaatcc ttttttttca
    24661 gatgttattc aatccatttc tgccgtttct gaacaaaata acttcgactt gattctacaa
    24721 acggcaaaaa caccagaaga agagctagaa aaatgcgcga aaaagatcca agaaaaaatg
    24781 atccgaggaa ttattatttt aagctctacg atggatgaaa cacttctttt tgaattggat
    24841 caatacaata ttcctattgt ggtaatcgga aaagtcggaa acgactacac gaacatctac
    24901 tcagtggaca cggataattt ccaggatagt tacgatttgg tggaaacact gatcaagaat
    24961 ggacaccgtc atatcggctg tctccatgct ccgacagaag tttatgtatc caatgatcgt
    25021 ctcaatggtt accgtcaatg cttatttgat caccacctag atatccgtaa tgaatggatt
    25081 atagacggcg gctttcgctt agaagatagc atggcagcaa tgaatgattt aatgaagcta
    25141 cgagaaagac caactgcgat tttttctacc gatgcattaa aatcattgag tatttacaaa
    25201 gtggcagaac aatctggaaa gcagatacct gatgatcttt cgatcgcagg attcagtgat
    25261 cccttattgt cctccctatt ttcgccacag ttgactcgga tagacattcc gacaaatcag
    25321 ttaggaatca aagccacaga acttttattc caactaatcc accaccaata ccctgaagaa
    25381 aaaagaatca ttctttcaac cgagattact ctcacagatt cgatccaaca acaagaaatg
    25441 tagaacagaa ttataaaaga acagaaacac tgaggataag tcagttactc tgttcttttt
    25501 tcaatcactc atccctcgtt accccctccc ggtattttag cgaatttttc ttattttcca
    25561 tctgttttag atagctgtgg ataactataa tgtttgtgtt aaactatttt ttccacaggg
    25621 aagaaaaaac tatttttaac cacgttgtgt ataagttttt atagttcgtt tttttaaaca
    25681 catttaccct tatttcaatc catgttattt ggggatactt atctctaaaa cataaataga
    25741 ataacagaca tgtctactgg ttttgtttta ttcgaggaat tattcaataa tagctagcaa
    25801 aatattaaaa ataaccgctc tatcttccca tcaatttatt ttgcattcaa aaaatgatct
    25861 atctttactt ttgttgattg acttctcttg gaagatgatc gttccgatac cttaattgga
    25921 tacgaaccga tgttgttaag atcctttccc acttttcttc tagttagaca aattatttta
    25981 gac
//
LOCUS       DAFLWC010000036        25334 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.037, whole genome shotgun sequence.
ACCESSION   DAFLWC010000036 DAFLWC010000000
VERSION     DAFLWC010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.037"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            28..1626
                     /locus_tag="L1V17_001389"
     CDS             28..1626
                     /locus_tag="L1V17_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236168.1"
                     /translation="MLFLSFAYVIPLFMSKGIYHSVNQDTYFHLSRIIGLDNVWSSPV
                     NFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFITFLTMVVSYFSMK
                     QIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLILMGCYEIYIRDYQK
                     WYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLLSLLKATVLTFFLS
                     AGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYTIGLFLFLGLIGAF
                     IFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVWRLNGFSSLFIAYT
                     MSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLTLIAPEDAVAIAEN
                     YNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIELDNSNNKNTVLTTP
                     IYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTKLAIASRYLSIVTL
                     ILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(1771..2511)
                     /gene="truA"
                     /locus_tag="L1V17_001390"
     CDS             complement(1771..2511)
                     /gene="truA"
                     /locus_tag="L1V17_001390"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBN1236169.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(2702..3337)
                     /locus_tag="L1V17_001391"
     CDS             complement(2702..3337)
                     /locus_tag="L1V17_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBN1236170.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(3484..4725)
                     /gene="sstT"
                     /locus_tag="L1V17_001392"
     CDS             complement(3484..4725)
                     /gene="sstT"
                     /locus_tag="L1V17_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HBN1236171.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            4923..5921
                     /locus_tag="L1V17_001393"
     CDS             4923..5921
                     /locus_tag="L1V17_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236172.1"
                     /translation="MFLSNFFVRCLFLKKIKKESYGFLTIFVACIMMVLQRILISAVT
                     IPTYATNPGRFYIYTFLQTSVVIGANLIPLYMGYQYQKIARLKVLHYLSRFAFIFLIA
                     TLVCNIFFYVQAGSLNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFI"
     gene            5934..7952
                     /locus_tag="L1V17_001394"
     CDS             5934..7952
                     /locus_tag="L1V17_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HBN1236173.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(8012..8728)
                     /locus_tag="L1V17_001395"
     CDS             complement(8012..8728)
                     /locus_tag="L1V17_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HBN1236174.1"
                     /translation="MKKRILVTIGLAFLLAGCTNGNESKKESTKETAKATVATTTTTS
                     TESKSTAASTETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNAD
                     KSAQLEAFMTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEW
                     SESGTGQADYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFN
                     ETANNELKNGFNQIVYGQAN"
     gene            complement(8955..9497)
                     /locus_tag="L1V17_001396"
     CDS             complement(8955..9497)
                     /locus_tag="L1V17_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBN1236175.1"
                     /translation="MNIVEEKFVQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLQQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(9502..9729)
                     /locus_tag="L1V17_001397"
     CDS             complement(9502..9729)
                     /locus_tag="L1V17_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBN1236176.1"
                     /translation="MKKIIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSAKVKEA"
     gene            complement(9808..11688)
                     /locus_tag="L1V17_001398"
     CDS             complement(9808..11688)
                     /locus_tag="L1V17_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBN1236177.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIMIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDEVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDRFSQYYTPTVLLIALVVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQTGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAKLKQAGAKQLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLR
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSNFESLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLNGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            complement(11877..12491)
                     /locus_tag="L1V17_001399"
     CDS             complement(11877..12491)
                     /locus_tag="L1V17_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1236178.1"
                     /translation="MKLTFKPLEKKDYKKAIYFAVEGMNFERYMENELLLNLYGRYFL
                     YMELNRATQILALYAEDELAGVLLAEIKGEKKKHRSFGQQIYVKIFDFLQNIFAKESK
                     GAYETANEQMLAAYLKKHSPDGEIIFLAANPDLKTKGIGTKLLTEFEKREKGKEIFLF
                     TDSGCTYQFYERRGFERLKEKISKIKILDKEIDLRCMLYRKIIQ"
     gene            12633..13193
                     /locus_tag="L1V17_001400"
     CDS             12633..13193
                     /locus_tag="L1V17_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1236179.1"
                     /translation="MKKTDRRVKKTEKALAETLSTLLVNKKIQAITIRELTETADVHR
                     STFYTHYKDIYDLYDQLESNFFRDLNEILSYDPAHSYEELYTRLIDYVYANTFLYRLF
                     ILNHGDISFQKKVKQVIEENYLNIWLYEDKKTIITEEMRFFTTYHVQGCLSVLNRWVE
                     SNYKYSKKELLELLQKLNDHIEKIMP"
     gene            complement(13498..13812)
                     /locus_tag="L1V17_001401"
                     /pseudo
     CDS             complement(13498..13812)
                     /locus_tag="L1V17_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
     gene            complement(14066..15701)
                     /locus_tag="L1V17_001402"
                     /pseudo
     CDS             complement(14066..15701)
                     /locus_tag="L1V17_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294751.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(16140..17009)
                     /locus_tag="L1V17_001403"
     CDS             complement(16140..17009)
                     /locus_tag="L1V17_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBN1236180.1"
                     /translation="MYGSIEAGGTKFVCAIGNDDLKVLERVSFPTTTPNETMSLVIDF
                     FNHYKEQLESIGVGSFGPIDIHRESKTYGHITSTPKTAWKNFDFVGTLNKHFEIPIAW
                     TTDVNAACYGEYVSGHGKGLSSVVYYTVGTGIGGGAIQDGIFVEGFSHPEMGHTLVKR
                     HSGDTFSGTCPFHHDCLEGLASGPAIEMRTGTKGQDLSIEDPFWEIEADYIAQCACNT
                     TLMLSPDIIIFGGGVMQQEHLKKKVQRRFLELINGYVDTPNIEEYIVTPKLADNAGTI
                     GCLTLAKDVRINS"
     gene            complement(17029..18150)
                     /locus_tag="L1V17_001404"
     CDS             complement(17029..18150)
                     /locus_tag="L1V17_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBN1236181.1"
                     /translation="MNCLNNIWLHKGEESRTISPENKNGEKGKAAMTASHLGIGRKGS
                     PSVPINAGETITLAEMEGPGILRHFWMTVTDKTIAGSFVLRDLILRIYWDDESTPSVE
                     SPLGDFFCNGFGTRCEVNSLPIVVNPTSGMNCYFEMPFRKKAKITLTNEHPEFIKHIF
                     YTFNYALTEVPDDAMYFHAKWNREPITTKGKDYTLIDGIKGTGYYVGTYFALCALERY
                     WWGEGEFKFYIDGDEDFPTITSTGAEDYFGGAWAFHKKNFGERAYAQNFNTLFMGYPF
                     QSKRDHTRDYFSAGKPNPNPVHGFGDDALPMHGLYRWHLPDPISFKENLRVTFQTLGN
                     DDIKLYERQDDISSVAYWYQKEPHEFFEKLLDREERIPR"
     gene            complement(18152..18547)
                     /locus_tag="L1V17_001405"
     CDS             complement(18152..18547)
                     /locus_tag="L1V17_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBN1236182.1"
                     /translation="MRRLIIASHSILAEGFKETLEFLTGMHNQISSLCAYVEEIDDID
                     EQIKELVDTTDEIIVLTDMAGGSVNQKFFTYISDRVHVIAGMNLPLAMSIALQLGNDN
                     LDIGAIIAEAQQQIIYMNNQKSEERIEDE"
     gene            complement(18566..19372)
                     /locus_tag="L1V17_001406"
     CDS             complement(18566..19372)
                     /locus_tag="L1V17_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBN1236183.1"
                     /translation="MNKMSEKYQVTKKDLRKANYRWLMSVCTFNYQTQQGASVTYALS
                     PILRKLYKDDDEYIEALNNHFQYYNTQPWLAAIILGACVAMEEKQGLEAKDAINDFKV
                     GTMGPIAGIGDSLLMTMIPTIMGSIAAYMALENNPVGIFLWFILIMVIFFFRMRGFEF
                     GYKQGMKIVTEYGEKINYLTEAASVLGLTVVGSLIASVISVSTPLKFTFGEVSMKIQP
                     MLDKILPTLIPVIITAAAYYLLSKKKISMTILILLVIVFAMVMAAFGILA"
     gene            complement(19365..20153)
                     /locus_tag="L1V17_001407"
     CDS             complement(19365..20153)
                     /locus_tag="L1V17_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1236184.1"
                     /translation="MHFTIFQIIMLTILAFIKHVDYYGIPMIFVNYAVFWGLFTGILM
                     GDIKTGLIVGGTVQLMSLGVAGFGGSSVPDYGTCAIIATAFGSQLGVEAGLAIGLPVG
                     MLGVQLDVIVKILNGFVVRKSQEYANKREFKKMNSVLWLGPIFFGLSAAIPVFIAVTL
                     GQSAVNYVLDVLPNWFMDGLTLAGKMLPAVGIAMLLRFMPTGRYISYLLVGFFLAAFL
                     KVPIIGAAIIGFALAFNVYHRAEKDAQITASAGASDVGFIGEDE"
     gene            complement(20167..20643)
                     /locus_tag="L1V17_001408"
     CDS             complement(20167..20643)
                     /locus_tag="L1V17_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1236185.1"
                     /translation="MSIVMSRVDNRLLHGIIVTQWAPMSKANRVMVIDDSVANNDIQK
                     SSMRLARPAGMAVSIITEETAIANFKKGKYDQEKVFVIVKEPETILHLVDNGIRIDRL
                     IVGGTVVKDNALQLSSRAYASDENISTYKKLLDSGVEIVTQFVPADKAQEIQSKLG"
     gene            complement(20715..23372)
                     /locus_tag="L1V17_001409"
     CDS             complement(20715..23372)
                     /locus_tag="L1V17_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBN1236186.1"
                     /translation="MEELKERIVNYVIENSEIKNKWGNNTAQKISEKLNVSRNIVSQY
                     LNEFVKDGEFGKINTRPVIFFSLPEKVPNQQIFSSSEEAEKWYDSSFRVGIERVIGSQ
                     GSLRNVIAQIKAAIYYPPNGLPILLHGETGTGKSYLANYVYKDLLANNYIEEKASFIS
                     VNCSEYANNPELFLSNFFGHVKGAYTGAEDGRKGLAELANNGVLFLDEIHALSNECQE
                     KLFQFMDTRKFHRMGDNENWYTSSCWIIFATSEPPEDKLLSTLLRRIPVKLTLPTLDS
                     RSLYERKQLIKIFFKSEEERLAKKILISQQLLDFLLNYRFSENVGNLKNIIQLTCANA
                     FYFLDDLEELYIQMYHLPQWVNFNGMKVMKRQNELKYIQMDDLEKVDEVFNINELIEY
                     LYQTWKKDTDKQQLFEKYDRYFRQKNVDIQNNSALTYPTYQEIRFRQYVKEIERDFQI
                     EFDYYYLQITSIFLNSWIYQIQLTSDDKLYSFINDINSWCSREVQLVNRFIQIGDIYL
                     TKIQKNVLVILFKLMCSKEFQQKRLALILAHGDLTATCIASTANRIVERYIYDAIDMP
                     LMTSSSEIADKINRYLQECTGYEEIILLVDMGSLEKIYLNLELDAQKKFGLLNNVSTR
                     MAIDVANQILLDLPLKQILEQVKENQNVDYIYESSNIKKDMIVCSCASGLGTSFKLKR
                     ILEDSFPRDTDLVIETCDYYSLVNENYLSELRKENNILFIVGTLNPHLEDVEFFSIED
                     MILGMNISKFSNQLNRHFNDNELKVLNNNILKNFSLTNLMEQLTILNPTKLLERVSDA
                     IYILQNDLGISFDNNTCFGLYVHISCLIERLVKQNTLEDEIYFNETSEEFQKFQTHFK
                     QSFSVVEHYYSVDIPIHEVKYVYDYVKRA"
     gene            complement(23391..23795)
                     /locus_tag="L1V17_001410"
     CDS             complement(23391..23795)
                     /locus_tag="L1V17_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit M
                     N-terminal domain-containing protein"
                     /protein_id="HBN1236187.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFLASHIYGKILSAKFE"
     gene            complement(24027..24284)
                     /locus_tag="L1V17_001411"
     CDS             complement(24027..24284)
                     /locus_tag="L1V17_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HBN1236188.1"
                     /translation="MEDSPELFPMLKDRLNELTEKRRQLQIRENEILGIFQQQGEPIQ
                     VKDVQQILTSLDCFLIQSEKKQVKALYHTFIEKITFDPNQK"
     gene            complement(24409..24741)
                     /locus_tag="L1V17_001412"
     CDS             complement(24409..24741)
                     /locus_tag="L1V17_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236189.1"
                     /translation="MPLDLSTGRKIRFSEIQYEGIGFTLIDLKNSTFEIKEGLDLKNL
                     LCADDKIKKIQLYKVPILTPTVLTMLEMENNINYIDSGSDLLIRWQVITNFLMELKKY
                     SNTQTKFS"
BASE COUNT         7982 a         4956 c         3833 g         8563 t
ORIGIN      
        1 aaaaaccaaa taatagatat catttttatg ttatttctaa gttttgctta cgtcatccct
       61 ctattcatgt ctaagggaat ctatcatagt gtcaatcagg atacttactt tcatttatct
      121 cgaatcatag gactagataa tgtatggagt tctccagtaa acttcaataa cttcgatcat
      181 catggaacaa tgatgaatat tttttatcca tggcttactc tttatccagc ttttttattt
      241 tataaaatga tgggaaatct tgttttaagt tataatatct actatttttt tatcactttt
      301 ttaacaatgg tcgtttctta tttttctatg aaacaaataa aaaacaatcg ttatatttcg
      361 ctgttatttt cgattattta tacattttcc gcctatcgtg ccattgacat attccatcgt
      421 gcttcattgg gagaagctgt cgctttaaca tttttgcctt tgatactaat ggggtgttac
      481 gaaatttata ttagagatta ccaaaaatgg tactggttgt ctattggcat gacgctagta
      541 gtgtatactc atttactttc tgtcgctatg gtttctgtat ttattggagg aacgttgttt
      601 ctttcttttt atttttggga ccaaaaaatc gctagactct taagtctttt aaaagctacc
      661 gtcctcacct tttttttaag tgcgggattc ttaattcctt ttattcaaca atctagagca
      721 caagaattga aagtcccact gggaaaagaa ttaagtggta tggctcctag tgatatgctg
      781 acacatattt taaataataa ctataacaac tatactattg gattattctt atttctcgga
      841 ttgattggtg cttttatttt tataaaaaaa ttaactgctg atgatttatt tattttcttt
      901 cttggtgtat ttgttctttt ttgttcaacc aatttatttc cttggcaact ttttaaccat
      961 acaccagtta agagtctaca atttgtctgg cggttaaatg gtttttcttc tttatttata
     1021 gcctatacga tgagtatagt gatctattat attttttcta ctaaaaataa ttcatggaaa
     1081 ataatggtct ttacgtttct tgcactaata ttgcatctct caggagtaag caattctatc
     1141 catgctaaca aagattcatt aacacttata gcacctgaag acgctgttgc tatagctgaa
     1201 aattacaatc atactgatta tgcaaacaaa gagtcaatct atcatcctga tatgattaat
     1261 aatgatcaat atttactagg taaccaggaa ataaatccaa caactcattt tatgagtaac
     1321 aaacttacaa ttgaattaga taattcgaat aataaaaata ctgtcttgac gacacctatt
     1381 tatcgttata aagggcaagt ggcttctatt aatggcaaac tagtacaaac aaaattatct
     1441 aagtttggca caactgaatt aactattcct ccaggtataa ataaagtcgt tattacttat
     1501 cagtacacaa aactagcaat tgcttcaaga tatttatcta tcgttacttt gattttattt
     1561 ttactttatc gatttacttt ttctaaacaa aaacaaccga gaagagaagt acaacattct
     1621 cactagattt ttatttaaga aagacttttt agctgtacac ataaacaggc taaaaagtct
     1681 ttttttatat ttctttaatt tgcttcatac attatttaac atcgatattt atactgtgaa
     1741 acatgcgttt catccattat caaagtattt ttatcgataa taaacttcat ccaaaaacag
     1801 accttgtgca gggacggttt ctcctgcatg ttgccgcact ttgctttcaa atatttcatc
     1861 gattgtttct atcggcatgg cacctgtgcc gatttctagt aatgtcccca tgataatccg
     1921 caccatttta tataagaatc cgtctccgac aaaagtaaaa tgaagcattt ctccctttcg
     1981 ttcgatagat aattcatcaa tcgtacgcac tgtggatttt tttgattttt tcaatgcaga
     2041 aaaaccaatg aaatcatgtg tacccactaa tttttcgcaa gctgcattca gcttgtccat
     2101 atccaactct tgagggaaat aaaagctgtg gtttcgctca aatgctgaag gaatcacgtt
     2161 gttccaaaca taatagctgt attttttgcc caccgcatta tatcttgaat ggaagcgctc
     2221 aggcatttct tcgattcttt tgatgacaat atcccgcgga aggtaacgat tcataaagtc
     2281 gatcatttct gccagtccaa tttctgtgtt tgttttaaaa tttgctactt gtcctcgcgc
     2341 atgggtgcca gcatctgttc ttcctgatcc aataatttct atctcttcat ttgtcatctg
     2401 atgcaatact ttttcgattt ttccttgaat ggttttatcg tcatctccaa gtctttgcca
     2461 tcctgaatat ctttttccgt catattcgat tgtcaacttg atgtttctca tattttagtg
     2521 gctcctctgt cttccatttg gtcttctctc taccttttta agattgtagc acaaaatata
     2581 gctccttgct tctctaagac agaagctata caagaaaact gtggaaatat atatttcaga
     2641 aaaacaaaaa acagccaccg gatgaagtat ccgctgactg ttcaatttga cggctcaagt
     2701 tttactgttt gagatgcaag atactcaacc aggcaatggg cacataatta aagaaaaaac
     2761 tgattctttg gcaaaaacct attttattca gtaatggcca agaatttata gaaggaattc
     2821 ttgccagtcc ataaatcgcc gcaaaaagca aactgatcac agacagtcca aggtataagt
     2881 ggcttacgtc catttgccca ttttttcgat agatcaagaa aagaagaact ggaaacaata
     2941 aaaaaccact gtaacctaaa cctgatccga tattatggac ccatgtcgag acattccacg
     3001 aagattcatg ggtattgata ctgaacaaac ctgtaaagat acaatcacct ataccataga
     3061 acgcgatggc tgctgtaact agggtagcta acacacgaga tgtactaaca aatgcagcat
     3121 acaatgcagg caatgacagg atgaaaaaga tccctgaaac cacagaccaa ataagaaacg
     3181 cttttcttac aggactggaa acctctccaa atacactgat cacgctcttc atttgatcta
     3241 attcaggata atacaatcct aatacgtacg gagtcaaaaa atcactcagc acgcctaata
     3301 ataaaaagaa aaaaccaaat ttacgtaaaa aatccatgat acgcctccaa taacaattac
     3361 ctatgctttt aattgttatt ataaacgact ttatcttgat ttaacagaaa cctctattta
     3421 cacgaacatc tatataactc attaaaaact cgaatcattt taaaaatact aaatatctaa
     3481 cgttcaacgt tcacttaatc catctaaaca atctttcaat ttgatttttt ccccacttct
     3541 tttacgcgcg cctagctctc ctattgcagt aaacaacaga tcacttgacg aatttaaggc
     3601 agtttccatt gaatcctgga taacaccgat aataaatcca ataccgacga tttgcatcgc
     3661 gacatcatta gagataccaa acaaactaca tgctaatgga atcaataaca gtgaaccgcc
     3721 cgcaacacct gaagctccac aagcagctaa agcagacaaa atacataaaa ggactttcaa
     3781 aacaaaaggt gcttcaatcc ctaaagaatg tacagcagtc aacgtcatca aggaaatggt
     3841 aatcgcggca ccgcccatat tgatcgtagc acctaacggg atcgatatgg aataagactc
     3901 ttttgtcaat ttcaatcttt cagccaacat catgtttatc gggatatttg cggcagaact
     3961 tcgggtaaag aaagcgggaa gtgcgctttc tttcaaacaa aagaaaatca atggataggg
     4021 attttcttta ataaacaaaa acgtgaggaa tgggtacaca actaatgcga caaacagcat
     4081 cgtaccgatc aaaacaagta aaagctgcag atactctgcc aatccagcga ttccagtcgt
     4141 agcaattgat tgataaacca atcctaaaat ccctatcgga gcaaatgcaa taatcacttg
     4201 tacgacttgt gacaacgcta tagatatctg atccaccaac tcttttgtcg attctgaacg
     4261 tgctcgaaaa gctagtccca acaatacagc ccagaataag acgccaaggt aattcgcatc
     4321 aataagagat tgaacaggat tttgtgtgac attcgtcaac atagtagata aaacactttc
     4381 caaactttgc ggtgcttttt cagatactgt ttcttgtaaa gtaataggaa cagtaaaaat
     4441 tgaacttaca ataactgcta caagtgcaga aagcaatgtt cccactaaat ataagatcaa
     4501 aataggcttc acgaatgtct tattcccaat tttatgcttg gcaattgacg ccatcgtcaa
     4561 gaaaaaaacc agaataggtg cgattgcctt caagcaactg acaaacaacg ttcccaatat
     4621 tgaaataaat gtccatgtgg ggaaaaagat accaaacaat attccgacta aaataccaac
     4681 aacaatacgt tgaactaacg acatatccaa aaacttctct aacaaatgac caccctttca
     4741 caattttaac aatcattgta tcattttatg caaagaaact aaaggtataa ttttctaaaa
     4801 attctaacaa tacaaacaac catttcttgc taattttgta ctttttctgt ctacacgttg
     4861 ttttttgaga tattctaagt taggatgtta ttaatgggca acttatcagg aaacgttttc
     4921 ttatgttttt gtccaatttt tttgtgaggt gtttattctt gaaaaaaata aagaaggaga
     4981 gttatggctt cctgacaatc tttgtcgctt gtataatgat ggttttacag cgtatattga
     5041 tttcagcagt cactattcct acatatgcaa caaaccctgg tcgattctac atctatacat
     5101 ttttacaaac ttccgttgtt attggtgcaa atttgatccc actttacatg ggttaccaat
     5161 atcaaaaaat cgcccgttta aaagttttac attatttaag tcgttttgcc tttatattcc
     5221 taatagccac actagtttgc aatatctttt tttacgtaca agctggcagc ttgaatattc
     5281 gtgattattg gcttatccta acacctatca gtcagaatta ctttacttat gctgtttctt
     5341 gtactttgct tttttgtagt attccttata cagttggatt tttaaataaa ttatcgaaaa
     5401 caacaattaa atatctacta ttatttttaa caattggatt agttggctgc tctactctat
     5461 ttaataaaga cccgtttgca ttacagaatg gacagagtat tttatggatt ttttatttat
     5521 ttttaatggg ttatggtttg aaagaatgga actggaaaga aaaggtccgc tataagcttc
     5581 ctcaagtatt tatcagcttg attgttttat tcggtttgat tattttgatg acacaaattt
     5641 cactcatcat cagaggaaat acagatacag cgctgaggtt ttctaaacca tattctctct
     5701 tcgcaatgta ttatactttc tcttcgtttt tatttttaga aatgctatct gataaattag
     5761 gtataaaagg aagaggaaat tttcttgctg tatttttgat tgtcactcaa gttatatgta
     5821 atttcccttt agtttcttat cgcgtatcta catttatgaa acgtgaattt ccaaactcag
     5881 ggaaggcatg gctgataaat atcgggcagt tttttatttg atatttatta gcagtgtccc
     5941 tcctagttat ctttttattt tatatacaaa aaatccgttt cattcatcgt ttcatcgaat
     6001 acttcgcttt tgattcgatt gaacaattaa ctcagcgttg gaaaaaaaga attcattggc
     6061 tttttgttca taaaagttat tttttagttg cagcattttt ttactgcttt accttcgtgc
     6121 agattttcgt tttagaacca aaagaaggtt ggaaagaaac tatccaggtt gccttaaaaa
     6181 tatttactca gcgacaagca cccatgatcc tgacaatcat cattattatg ggatttttct
     6241 tcttactatt gttgatttcc aatcgttttt ggtacgcctt gactgctacc ttgatcatta
     6301 acttactgct cactatttcg acagtaatca aaatggaaat gcgggaagag cctgtctttc
     6361 cttcagattt aaaaatgctg accggattgt cagaactatt atcgatggtt agcccagtct
     6421 tattaatcgt gggcggattg atccttctcc tattattgat tactagtatt attgtacaac
     6481 gtagactaca aaaacagtat tccttgaaga ttcattggaa acgtcgattt atcagtatcg
     6541 ctgtattatt aggatgtttt tcgggtgtct ttttcattaa tcacaaaaat tcgccttctt
     6601 tcttgctgtt taatttattt aaagtaaaca agactttctt taaccagcaa ggcgccgtaa
     6661 aagataacgg accagtcatt caattcctaa acaatatcga cattaaaatc atggaagaac
     6721 ctgctggcta ttcgaaagaa aaaattaatg gaataatgaa aaagtacaac acaaaggcag
     6781 atgaaatcaa ccaaacaaga agtgactggt taaacaatca gacgatcgtt ctcaatttaa
     6841 gtgaaagctt cagtgatcct gcacgtgtcc ctaatctgac agtacctaca gaccctattc
     6901 cttacatcaa aagcattata acagaaggaa caggaggatt gatgttatcc gtcggttatg
     6961 gtggcggaac agctaacatg gaatgggaag gactgacagg cttgagtatc agtaacctgt
     7021 ctgcttcgtt agttacacct tatacccagc tagtggagcg tcagaaaata agtccaaata
     7081 ttaccgatct attcgatgaa aaaatagcca tccatccttt tacagctgct ctttatcgca
     7141 gaaaacaagt gtttgataaa tttggttttg acaggttcta ttatttagac agtccggata
     7201 aattaactta tacggataaa atagaacaaa gcccacgcat atcggatgat tcagcataca
     7261 aagaaacctt gaaagcttta caaagcaata cggaaacgtc acaattcatc caattatcca
     7321 ctatgcaaaa ccatatgcct tatgatgatt actatagtga attgaactac actgctgaag
     7381 gaactgctgt cattcctaat agaagaaaag aattacaaac ttatatgcaa ggccttcact
     7441 ataccgatac agcagtaaaa aaattcatcc aagaaatcga caaaatcgat aaaccgatta
     7501 cctttgtttt ttatggtgac catttacccg caatctatag tgggaatgat tcgaaaaaat
     7561 atggattaga acagcaccag acagattatt tcatttataa caacaagtat agtcgtgaac
     7621 aagcagctac gttaaataaa gaagttgttg ctcctaataa ctttggtgct atggctcttg
     7681 agcatgcgaa tatcaaagta actccttact atgcgttgtt gacagaagta tctaatcatc
     7741 tacctgcatt aacaattgat cctacagaaa gcttgtctaa tcgttttaat ggaaaacagg
     7801 tctttgttac agaggatagt caaattatcc aagaaaaaaa tttaactgag aaacaaaaag
     7861 aaattctaga agattatcgt ctgatacaat atgatcttgt tgcaggtaac cagtacagtg
     7921 caacatgggc gacacaaaaa ataaaagact aacaaataaa ctgagcaagg ggttgtgata
     7981 aaagacatgt cacaacccct tgtttatctc attaatttgc ttgtccataa acgatttgat
     8041 taaagccatt tttcaattca ttattcgctg tctcgttgaa gtaaagataa ttatcgggat
     8101 tcccctgatt ttgttgtgtc accaatactt ttggctgatt ttgctgaaac ccgaatagat
     8161 agacgtgctt tttcagatat ggttctgtct ctgcatcgga atagacggct gtgatttgat
     8221 agtctgcttg acctgtccca ctttctgacc attctgcaga aacaggcact ccaccaatag
     8281 ccatcttcca ctccccgttc aaaatagctt gagggacttt aagaccatat aagtccacac
     8341 tcatttgatt cgtataactt ttgtattgtt gtcccattgt ttggccccat ttggtcataa
     8401 atgcctctaa ttgtgcggat ttgtctgcat tccacagtgt ttgttcaact tgttcgctgc
     8461 tttctgaaga ggaagatgaa gcctctacag aagaacttga agtagatgtt tgagttgttt
     8521 cagtcgtttt ggaagactct gacgaagtag aggtatctgc tgtttctgta cttgctgcag
     8581 ttgacttgct ctctgtgcta gttgttgtag tagttgcaac tgttgctttc gctgtttctt
     8641 ttgttgattc ttttttcgat tcattcccgt tggtacaacc agctaacaaa aaagctagac
     8701 caattgttac taaaatcctt tttttcaatt aaaaaactcc tttcgattac tcccacttct
     8761 ttattctatc aaataagcaa tgtgatttta ttgatttttc gtattttctc atcaatcttt
     8821 caaatcttct aaaaactgag aagcacccgc tgatgttgtc tgtaatacat cagcgggtgc
     8881 ttcttttatt ttaatcttcg tgattttcca atttacctca cgctttatat ttgtatttga
     8941 agaaacatag acttttagtc atcatcgtct tcctcatcca aatcttgtcg gacagttttt
     9001 ccttggagtc tttgtacttg gtagatgatt tctttattga aacttaaaag ttcaacaagc
     9061 aattgttgca agccatattt ttcttctttt tcagctaatt tgattgcccg tgtgataaag
     9121 acattttgga aatcaaaatc ttttgcaaag ttttccaaca ttgttgaggc tggtaaatat
     9181 ttgttttgac catgttcgta aatttttcca taacgcatga cttcttctaa agtagacgga
     9241 acgatttcat tttcaatcac taactcatga gagattttat tgaaccatct cgcttcttga
     9301 tcagcatatt ctgaaaaaag ggtacttaat tcttgcgaag atgtacccaa aacatacaat
     9361 tgtgcttgga tcaatttcat ttcttctaat ttaaaatttg ctaatacatg ccccaccatg
     9421 gcgccagcag ttggtttatg atggtcgata tctgcttgtt ttgtttcttg aacaaatttt
     9481 tcttccacta tattcattga tttacgcctc ttttactttt gctgattgga cttcataacc
     9541 taatttttcc acaactgcag ctaattgttc agggtggact tcatctggat caaagtttgc
     9601 tttgattttg ctcgcattaa acaaaacttt cgtattgctt accccaggct gttgagaaac
     9661 cgcatgttcg attttttgca tacagcttgg acaagctagt gtatctaatt gcataataat
     9721 ttttttcatc gtagttcttc cttccttttt cttgatagtc ttattctaga ttacagcttc
     9781 cataaaaaaa ttgattctta tcaagtttta cgatttttct tctttgcttt cgtgtccaaa
     9841 atacaataaa cgcatcgcgt taaagataac gatcaagata ctagcttcgt gaacgaacat
     9901 cccactagcc atgtaaataa acccggcaaa taagccgttg agtaaaaata agacgacacc
     9961 aatggcaatc actacatttt cacgggtatt taaaacagtt ttcttagcca agcggtaggc
    10021 atgaaccaac gattcaaaat tagattgcat caagacaacg tcactcgttt cgatagcaac
    10081 atccgttcct gatcccatag caatcccgat atcagccgca gccaaagagg gagaatcatt
    10141 gattccatct ccaataaaag caacgcgcaa tccttgttct tggtattttt tcacaaattg
    10201 aaccttttcg tctggtaata attcagcatg gacttcatca atgcctaaca tatcagctac
    10261 ataatcagca gtcatctgat tatcacctgt cagcatcact aactgttttg ctcctgcttg
    10321 tttcaactta gctaattgtt cagcgacttc tggtcgaatc acatctgaca cacctatgat
    10381 ttgagtgatt tttttgtcga ttgctacaat aatgaccgag ctgcctgttt gttgtaattg
    10441 atgtaaatct tgtacttgct ttggtgtgag agaaagtttg tgagcggcaa tcaatttggt
    10501 gttgcccgca caaactgtat gaccatcaat ctcagctgtg attccttgtc ccttgattgt
    10561 ctgattatct ttgactgcta attgttgaaa atcaatgtct ttctcctgag cataatggat
    10621 cacggcgcgc cccagaggat gatcggataa cgtttctaat cgagccacta aagctaagct
    10681 gtccccttca tcctctgtat agttcttgat agtggataca gcagtagttc ctttggtcaa
    10741 tgtaccagtt ttatcaaaga caaaagtatc gattttggaa aaagtatcca ttgcttcacc
    10801 gcctttgact aagatgcccc gtttcgctcc attaccgatt cctgctacat tcgaaacagg
    10861 cgcaccaatg actaaagcgc caggacaacc aagaaccaaa acagtgattg ctaaacgaaa
    10921 atcacgacta atcagaccaa caaccaacgc aataagtaaa acggttggag tataatactg
    10981 agaaaatcga tcaatgaatt tttccgcatg ggatttggta tcttgtgctt cttctactaa
    11041 ttcgataatt ttggcaaagg tcgtatcatc tccgacctta gttgcttcaa tcgtcacgta
    11101 gccatctgct aaaatcgttc cagagaagac ttcatctcca ctgattttga cgacttgtcg
    11161 tgattcacca gtcactgcgg cttcatccgc ataccctttc ccgtcaatga ctcgtccgtc
    11221 cacaggaata gctccaccag tttttactaa gacgatatcg ccttcttcca cgtcatcgat
    11281 ttccacttct tcagtcgttc catcttcttg gacaacacta gcagtagatg gggccatctc
    11341 ggtcaaagcc ttgattgact cccgcgtttt ggtcaatgtt ttttgttcca gatagctacc
    11401 aaacaaaaac aagaatgtaa cgatagctga ctccttgtat tctccgatca taaaggcacc
    11461 aagcacagca atagtaacga gtaaatcaat tgagataact ttgactttca ctgcctgata
    11521 cgcatggatc ataataggta tgaccgcaat aatagaagct atggctagag caatgttata
    11581 gaacaagaca aaaccagtaa attttccgat aaaaccaaaa ataatcaaca cagctgataa
    11641 ggcggtgata tgatttcgat gctcttggat ccacttttgt aatttcatct ttctccctct
    11701 tttcctttca ttcttacgag actaagtata gatacttatc catcataaaa aattgaccac
    11761 tatcaagttt agtcaaaaag gcggttttct tttggtagaa tacactacaa aaaatagtta
    11821 gcaagaagac tcactaaaag tgatcttgcc aactattgtc gtttctatcg aaattttcat
    11881 tgaatgattt tcctgtacag catacatcgg agatctattt ctttatctaa gatttttatc
    11941 ttgctaattt tttcctttag tctttcaaat ccacgtcgtt catagaattg atacgtacag
    12001 ccactatctg taaaaaggaa tatttctttt cctttctctc ttttttcaaa ttctgttagc
    12061 aacttggtac cgatgccttt tgttttcaaa tcaggatttg cagctaaaaa aatgatctct
    12121 ccatctggcg aatgcttctt taaatatgct gcaagcattt gttcatttgc tgtctcgtaa
    12181 gctcctttac tttctttagc aaatatattt tgtaaaaaat cgaatatctt aacatatatt
    12241 tgctgtccaa aagaacgatg tttctttttt tctcctttta tctccgccag caaaacacct
    12301 gccaactcgt cctctgcata caaagcaaga atttgagttg ctcgattcaa ctccatatac
    12361 aaaaaatatc ttccgtaaag attcagcaga agttcatttt ccatatatct ctcaaagttc
    12421 attccttcaa cagcaaaata gatagctttt ttgtaatctt tcttttctaa gggtttaaaa
    12481 gttagtttca tcatttcgcc tcctcaactt caatgattgt gttatactta cattataata
    12541 gacacagtgt ctactatcta taatcaatca tctataagtt tgtcgattaa gcgacagctt
    12601 tgctttgata tgtcggataa ggagataggt aaatgaaaaa gacagataga cgcgtcaaaa
    12661 aaacagaaaa agctttggct gaaacactat ccacattatt agtaaataaa aagattcaag
    12721 caatcactat acgcgaacta acagaaacgg cagatgtaca tcgttcgact ttttatacac
    12781 attataagga tatctatgat ctatatgatc aattagaaag caactttttt cgggatctaa
    12841 atgaaattct ctcttatgat ccagcccata gctatgagga actatacact cgcttgattg
    12901 actatgttta cgcaaatact tttttatatc gcttatttat cctcaaccat ggtgatattt
    12961 cgtttcagaa gaaagttaaa caagttattg aagaaaacta tctgaacata tggctatatg
    13021 aagacaagaa aacgattatc acagaagaaa tgagattctt tactacgtac cacgtccaag
    13081 gttgtctatc cgttctcaat cggtgggtag aaagcaatta caagtactcc aaaaaagaat
    13141 tattagaact cttacagaaa ctgaatgatc acatagagaa aatcatgcct tgaataaaaa
    13201 catactaagc ttagttaaga agaaccgtaa ccttctcgta taacaactga atcttattta
    13261 gccaaattgt ttactgaaga ttttttgagt aaaatttcta taattcctac ttattgaaaa
    13321 gtagtttgta gtgctgcttc tccctctcta agtgatatat cttgttgtac caatcaaatt
    13381 cacctcatca ttaataaatt acttttaggc taatttatta caacttatag gttgaagctg
    13441 taaccaattt atagtcatat tatattttta tcatccagtt tattgaattc ttctcgttta
    13501 cctcaattca ttttcaaggg gaatcagctc atcatctaac attttacgcc atgctcgctt
    13561 catttcttgt gggtatttaa atggtttcgc ttctggatgt ttggctttat atccttcgta
    13621 atccttactg ttgataattg ctttcatatt aggaattgga tcttcacctg gcatatattg
    13681 cagattagaa gcatgtaatt ttttctcaga aacaaaccac tcattggaaa agacatgaat
    13741 caaatcatca cttacttgtg taaaatagcg acgtttaatg acaaagatat cttcattgct
    13801 atctagtgta ccttcatttc tttgtgctta aattcaaaga taattttctc aataaagatt
    13861 tttgattcca gtaagattcc tttactcctt ttacaacata gcgttgtcct ttgttttgaa
    13921 acatcttctt cccctctttg ccattaaaaa tagcccaatt ctctataaag aagattaagc
    13981 ttcattatta taatataaag tttaaatttg gtttattact tactttttct tattctctag
    14041 taagctaata ttgaaaaaaa tgtaatcaga tcattatttt tatatgttgt aacttcctga
    14101 taagaaaact aattaaaaga aagaggtaac tacataaact aattaaaaaa gctaacttca
    14161 tagttggagg ataaatggaa gaaacttcaa tgattgtttc tccttgtgtt ccttcaatcg
    14221 acactagtcc tattatcaat ctctcttttt tgtccattta cttttgcgac tgttccccaa
    14281 taatcaaata caggaagcgt tattttttgt cctttagatt catgtactgt atagactatt
    14341 ttcgaatcca tcacttgata aggcatagta tgccattcct tgccaattct tacttcatga
    14401 ttctgcaaat gttctttgta ttgtaatgct tccgtgggtg catagtcata aagtcctccg
    14461 ggaaggagtg tcgtgtaacg aataagattt tcttgattca ttaccaagtg atctctctga
    14521 gtgacaactt tatgttcata gtttgctttt gttgcagcag atacagccaa cagtaataaa
    14581 acaattgccg ttatattaac tacttttctt tgcttagctg atgtgctctt catgaaaacg
    14641 aacgataaaa tcaacgagcc aaacagtact tgaaagccta agattcgcca aggaaattga
    14701 atcatttgaa tgggtgtatt ttgtaataaa gaccatggaa aaaatttggt ggataagagc
    14761 caagagacta ccgcactaag gtaaatcact ttttctttgc gattaaatcc tttaaaaaag
    14821 aagagtggac agatcaaaga aataatacca atgattccta ccgtaaaggt tgtcaggtca
    14881 ttattcatcg caccaatcaa actatccgag acatttaatg cttggtgttg taaggtcgtt
    14941 ttatctggct cattaatcga ttgaaccatg atttgtcgga acatcggata ccaaaagtat
    15001 gctgttaaaa gaatcgtcat tcctactgcc tttgacaact ccacaatcaa ccggatgctt
    15061 tctttttttc ttgtttcact tactacaaag ccgcctaaga ctagtaagcc aacggctatt
    15121 acactcataa aagtggaaag aacatgtgta taaatgagta agctcatact gactgctaat
    15181 ggaattgcac atggcttttt ctcataaatc agtgcgtaag cataatacat aactatcggt
    15241 ataaccgtaa gtgcaatcgc ttcagcaata gcagaacgat gataaatatc aatcgtacgg
    15301 tacccataaa atgtatataa acagctaaat ataaaagccg catcgattct ttttaaaaat
    15361 tttagtccat aatgaaacat cagcatgata gtacaaacat tcaatagcca aacatataag
    15421 atataactaa cgattaaatt attacttatc caataaaaaa tgactgccgg aaaaaaggtc
    15481 aagtagggat aaaaataatt cactccgctc ccataatgat taaacgtcgt aaaattgatt
    15541 ggaccagaaa aaattgaaga taaccctttg actctagcaa aatggaaggc aatatccccc
    15601 gatgtagaaa tagtatgaac atttctaaaa taattgattg aataaagtcc agcaataatt
    15661 gctaggagaa tggacaatat tatttttttc tttacttgca ttacttaatt atatactcct
    15721 ttcatggatt gctttatcta gtataactta aattttaaat aaatcgttat ttatttttac
    15781 tctcacttaa aaaagcacta aaattataag agagggaggt aatggtctga acaccaagaa
    15841 ttgttccaac atcgaattgc ttaactaatg agttcaaagc ttaattatgt ggctcttata
    15901 tttaccgagc gtggattgcg atctctttag cgaaacaaac atctttcata aaaaaaacag
    15961 ccatatccgc tttcttggat atgactattt actactactt tactatcttt cattcttctt
    16021 gtctcactta tgataaggcg ctgggtatca tgagtgaatg atattgctga atacaaatag
    16081 tccgaccaca ttaagttgat cggacttcat aagcatttta ttgactaata cttttttgct
    16141 taagaattga ttctaacatc ttttgctaaa gttaagcatc ctatagttcc tgcattatct
    16201 gctaacttag gtgtgacaat gtattcttcg atatttggcg tatcgacata gccgttaatt
    16261 agttctaaaa aacgtctttg tactttcttt ttcagatgtt cttgttgcat gacaccacca
    16321 ccaaaaatta taatatctgg tgaaagcatc agggtcgtat tacaggcaca ttgtgcaata
    16381 taatccgcct cgatttccca gaacggatct tctatagaaa gatcttgtcc cttggttccc
    16441 gtacgcatct cgatagcggg tccagatgcc aacccttcga gacaatcatg atgaaaagga
    16501 caagtaccag agaaagtatc tcctgaatgt ctcttaacta acgtatgccc catttctgga
    16561 tggctaaacc cttcaacaaa aatcccatct tgtatagctc ctccaccaat tccagttcca
    16621 acagtgtaat aaacaacact ggataaacct tttccatgac ctgaaacata ctccccgtaa
    16681 caagcagcat tcacatcggt tgtccaggca attggaattt cgaaatgctt attcaacgtt
    16741 ccaacaaaat caaaattttt ccaggcagtt tttggagtag aggtgatatg tccataggtc
    16801 tttgattcac gatggatatc aatcggtcca aatgacccta ctccaatgct ttctaattgt
    16861 tctttatagt gattaaagaa atcaattacc aaactcattg tttcattcgg tgtagttgta
    16921 ggaaaactca ctctttctaa aacctttaaa tcatcattgc caatggcaca aacaaattta
    16981 gtcccacctg cttctattga gccatacatt tcttactcca ccgtcctttt atctaggaat
    17041 tcgttcttcc ctgtctaata gtttttcgaa aaactcatgt ggttcctttt ggtaccaata
    17101 ggcaacagaa gaaatatcgt cttgacgctc ataaagcttg atgtcatcat ttcctagggt
    17161 ttggaaagta acacgtaaat tttctttgaa actaatgggg tcgggtaaat gccagcggta
    17221 caacccatgc atcggtaaag catcatcgcc aaaaccatga actggatttg gattaggttt
    17281 tccagcacta aaataatccc gggtgtgatc tcttttagat tgaaaaggat agcccataaa
    17341 tagcgtatta aaattttgag catatgccct ttctccaaag ttctttttat ggaaagccca
    17401 agcgccgcca aaataatctt ctgctcctgt agatgttatt gtagggaaat cttcatctcc
    17461 atctatataa aacttaaatt ctccttcccc ccaccagtat ctttccaatg cgcacaaagc
    17521 aaagtaggtt cctacataat acccagtgcc tttgattcca tcaataaggg tgtaatcttt
    17581 tccttttgtc gtgatgggtt cacggttcca tttagcatga aaatacatcg catcatccgg
    17641 tacttcagtc aatgcataat taaatgtata aaaaatgtgc ttaataaact caggatgttc
    17701 attcgttaaa gtaatcttag ctttttttcg aaatggcatc tcaaaatagc aattcatccc
    17761 tgatgttgga ttcactacga ttggtaagga attcacttcg catcttgtcc caaacccatt
    17821 acaaaaaaaa tctcctaatg gactttctac agaaggagtg gattcatcat cccaataaat
    17881 acgcaaaatt aaatcacgta agacgaaact cccagcgatt gttttgtctg tcactgtcat
    17941 ccaaaaatga cgtaaaattc cagggccttc catttctgct aaagtaattg tctctccagc
    18001 atttatcgga acagaaggtg acccttttct cccaattcct agatgactcg ctgtcattgc
    18061 cgctttccct ttttcaccat ttttattttc tggtgaaata gttctacttt cctctccctt
    18121 gtggagccat atattattta aacaattcat tttattcgtc ctctatcctt tcttcacttt
    18181 tttgattatt catatagatg atttgttgtt gtgcctccgc aataattgct ccaatatcta
    18241 aattatcatt tcctaactgc aaagcgattg acattgccaa gggaagattc attcctgcaa
    18301 ttacgtgcac tctgtcagaa atataggtaa aaaacttttg atttacactt cctccagcca
    18361 tgtcagttaa aacaattatt tcgtctgtag tatccactaa ctctttaatt tgttcatcta
    18421 tatcatcaat ttcttcgaca tatgcacata agctactaat ttgattatgc atacctgtta
    18481 aaaactctag tgtctcttta aaaccctcag ctagtattga atggctagca atgatcaatc
    18541 ttctcataat tcaaatcctt ttcctttacg ctaatattcc aaatgcagcc ataaccatcg
    18601 caaaaacaat aacgagtaga atcaaaatgg tcatactgat ttttttctta ctgagtagat
    18661 aatatgctgc agcagtaata attactggaa ttaatgttgg taaaattttg tccaacattg
    18721 gttggatttt catactaact tcaccaaaag tgaatttaag tggcgttgaa acactgataa
    18781 ctgaagcaat taatgatcca actactgtta gccccaatac tgaagcagct tcagttaaat
    18841 aattaatctt ttcaccgtat tcagtaacaa tcttcattcc ctgcttataa ccaaattcaa
    18901 agcctctcat tcggaaaaag aagattacca tgattaaaat gaaccataaa aagattccta
    18961 caggattatt ttctaaagcc atataagccg caattgatcc catgatggtt gggatcatcg
    19021 tcatcaaaag agagtcccca ataccagcaa ttggacccat cgtaccaact ttaaagtcat
    19081 taatcgcatc ttttgcttct aatccttgct tttcctccat tgcaacacaa gcacctaaaa
    19141 taatggctgc cagccaaggc tgtgtattgt aatactgaaa gtgattattt aaagcttcga
    19201 tgtattcatc atcatctttg tataattttc ttaaaatagg tgacaatgcg taagtcacag
    19261 atgcaccttg ctgtgtttga taattaaagg tacaaactga catcaaccaa cgatagttcg
    19321 ctttcctaag atcctttttc gttacttgat atttttcgct cattttattc atcctcccca
    19381 ataaacccaa catcagaagc tcccgcagaa gcagtgattt gtgcatcttt ttcagctcta
    19441 tgatacacat taaatgctaa agcgaatcct atgatcgccg ctccaataat aggtaccttc
    19501 aaaaaagcgg ctaagaaaaa tccaacaagt aaataactaa tgtatcgacc tgtaggcata
    19561 aagcgtaaca acatcgcaat accaacagca ggcaacattt ttccggctaa tgttagccca
    19621 tccataaacc aattaggtaa aacatccaaa acgtaattaa cagcagactg tcctaaagta
    19681 acggcaataa atactggaat tgctgcagat aaaccaaaga aaattggccc caaccacaaa
    19741 acactattca ttttcttaaa ttctcgttta ttcgcatatt cctgtgattt gcgaacaaca
    19801 aaaccattta agattttgac aattacatct agttgcaccc ctaacatacc tacaggtagt
    19861 cctattgcta atccggcttc tactccaagc tggctaccaa atgccgttgc aataattgcg
    19921 cacgttccat agtccggtac agatgagcca ccaaaaccgg caactcctaa tgacatcaat
    19981 tgaactgtac cgccaactat caaacctgtt tttatatcac ccatcaaaat tcctgtgaat
    20041 aatccccaaa aaactgcgta atttacaaag atcatcggaa tcccataata atcaacatgt
    20101 ttaataaatg ctaatatagt cagcataata atttgaaaaa tagtaaaatg cattatcctt
    20161 actcctttat cctaattttg attgaatttc ctgtgcctta tccgccggaa caaattgtgt
    20221 aacaatttct acaccagaat ccaacaattt tttatacgtg ctgatatttt catctgatgc
    20281 ataggctcta gaagatagct gtaatgcatt atctttaaca acagtaccgc caacaattag
    20341 tcggtcaatt ctaataccgt tatctactaa atgaaggatt gtttccggct ctttcacgat
    20401 gacaaatact ttttcctgat cgtatttccc ctttttaaaa ttcgcaatcg ctgtttcttc
    20461 agtgataatt gatacagcca ttccagcagg tctagctaaa cgcatacttg atttttggat
    20521 gtcgttattt gcgacagaat catcgatcac catcactctg tttgctttag acattggtgc
    20581 ccattgcgtg acaataatcc catgcaataa acggttatca actctcgaca taacaatact
    20641 cataaatact tcctccttta tctttcattt tcttacaagc aattaccatg ccaaaacaaa
    20701 aagaacttga taaatcaagc tctttttaca taatcataaa cgtatttaac ctcatgaatc
    20761 gggatgtcga cactataata atgttcaacg acactgaaag attgcttaaa atgtgtctga
    20821 aatttttgaa attcctcact cgtttcattg aaataaattt catcttccaa agtattttgt
    20881 tttactaatc gttcaattaa gcaactaatg tgaacatata atccgaaaca cgtattatta
    20941 tcaaatgaaa ttcctagatc attttgtaag atgtatatag catctgaaac ccgttctaat
    21001 aatttagtcg gatttaatat ggtcaattgc tccattaaat tcgttagact aaaattcttc
    21061 agaatattat tgttcaaaac tttcagttca ttatcattaa agtgtctatt caattgattg
    21121 gagaatttac ttatattcat tcctaaaatc atatcttcaa ttgaaaagaa ttctacatct
    21181 tctagatgtg gatttagtgt tccaacaata aaaagaatat tgttctcttt acgaagctcc
    21241 gataaatagt tttcattcac taaagagtaa tagtcacacg tttctatgac aagatcagta
    21301 tcccttggaa agctatcttc aagtatcctt tttaatttaa acgaagttcc taatccgctt
    21361 gcacaagaac agacaatcat atccttctta atatttgatg attcataaat ataatccaca
    21421 ttttgatttt cttttacttg ttcaagaatc tgtttaagcg gtaaatctaa taatatctga
    21481 tttgcaacat caatagccat tcttgttgaa acattgttta gtagtccgaa ttttttttga
    21541 gcgtctagtt ccaaatttag ataaattttc tccagtgaac ccatatcaac aagtaaaata
    21601 atttcttcat atccggtaca ctcttgtaag tatctattaa ttttgtctgc aatctcacta
    21661 cttgaagtca ttagtggcat atcaatggcg tcgtatatat atctctcaac gatcctatta
    21721 gcagtacttg ctatacaggt tgccgttaga tctccatgag ccaaaatcag tgctaaacgt
    21781 ttttgctgaa attctttact acacattaac ttaaataaaa taaccaaaac atttttttga
    21841 atttttgtta aataaatatc ccctatttga ataaaacgat tgactaattg aacttctcga
    21901 ctacaccaac tattaatatc attgatgaag gaatataatt tatcgtccga tgttaattgg
    21961 atttgataaa tccaagaatt caaaaagata gacgttattt gaagataata atagtcaaat
    22021 tctatttgaa aatctctctc tatttcctta acatactgtc taaatcgaat ctcttgatag
    22081 gtgggatatg ttaaagctga attattttgg atatcaacat tcttttgtct aaaatatcta
    22141 tcatatttct caaaaagctg ctgcttatca gtgtctttct tccacgtttg ataaagatac
    22201 tctataagtt cgttgatatt aaaaacttcg tctacttttt ccaaatcatc catttgaata
    22261 tattttaatt cattctgtct tttcataacc ttcatgccgt tgaaattcac ccattgtggt
    22321 aaatgataca tctgaatata aagttcttcc aaatcatcta agaaataaaa ggcattggca
    22381 caggtcaatt gaatgatatt tttcaaattg ccaacatttt cactaaagcg atagtttaat
    22441 aaaaaatcta ataattgttg agatatcagt attttctttg ctagtctttc ttcttctgat
    22501 ttaaaaaata tcttgattaa ctgttttctt tcataaagag aacgactgtc taatgttgga
    22561 agtgttagct ttacaggtat tcttctcaac aaagttgata atagtttatc ctcaggtggt
    22621 tctgatgttg caaatataat ccagcaactt gatgtgtacc agttttcatt atcacccatc
    22681 cgatgaaatt tcctcgtatc cataaactga aaaagtttct cctgacattc attgctcaat
    22741 gcatgaattt catctaaaaa taagactcca ttattagcta attctgctaa accctttctt
    22801 ccatcttcgg ctcctgtata tgcacctttt acatgcccaa aaaaattgga caagaaaagt
    22861 tctggattat tggcatattc actacaatta actgaaatga aagatgcctt ctcttctata
    22921 taattattgg ccaacaaatc cttatacaca taatttgcta aatagctttt tccagttcca
    22981 gtctcgccat gaagtaaaat gggtaagcca tttggcggat agtagattgc tgctttaatt
    23041 tgagcaatta catttcgcag acttccttga cttccgataa ccctttctat tccaacccta
    23101 aaagagctat cataccattt ttccgcttcc tctgaagagc taaaaatttg ttgatttgga
    23161 actttctccg gtaaagaaaa gaagattact ggacgagtat tgatttttcc aaattctcca
    23221 tcttttacga attcattcaa atattgagag acaatattac gactaacatt taatttttca
    23281 gatattttct gtgctgtatt gttcccccat ttatttttaa tctcagagtt ctctatgaca
    23341 taattgacaa tgcgttcttt taattcttcc atcacagcac ctcctcgaca ctattcgaat
    23401 tttgccgaca gtatttttcc ataaatatga cttgctaaaa aggctttgtt tagatcattc
    23461 aattggaacg ttgcttgttt tgcttgatcc gctaagacgt tgaaaagata ctctggcgaa
    23521 atcgcatacc ccaaaatatc aacgattgtt gcaatcagat cttcttttga ttcttcatct
    23581 gaaagtaatt cacgatacaa catcgtttgt ttgcttactg tgtcatattc ctctaaggat
    23641 tcatctgcta aaagaaccac ttgttccaac aaacggtcgg ataaatattt atagaaaatc
    23701 agccccaata aataattttt atattctgac gcatccattt tactacggag attatctgcc
    23761 gcactaaata acttctgatt taattctgca cccaaaaaga tacactccta tctcttattt
    23821 aaagttgcta tataccctct tattttagca tactcagttt tagaaaaagc aaaaaaataa
    23881 agaaacttat tcttgataac aagctacgtg acgtatatcc ctaacacaaa aatagccata
    23941 tcctttggtt tggatacggc tatttgatat tactcattca attatcaaat cacagtaggt
    24001 gtgaatctca tcgggatcgg caatatctac ttctgattag gatcaaaggt gattttctca
    24061 ataaaggtgt gatacaaagc tttaacttgc ttcttctcac tctggataag aaagcaatcc
    24121 aaactagtca atatctgttg gacatctttg acttgaatcg gttccccttg ttgttgaaag
    24181 atccctaaga tttcattctc tcgaatttgt aactgtcttc gtttttcagt caattcattt
    24241 aaacgatctt ttaacatcgg aaacaattcg ggactatctt ccaaagcagc ttcctgtttt
    24301 tgctctaata gttagatttt gcgtaccatt ttcttctttt attttccttc gattgctgat
    24361 tttaatatag tctaaaggaa atttatattt attgtattct ttataacttc aagagaactt
    24421 cgtttgagta ttactgtatt tttttaattc cataagaaaa ttagttatta cctgccacct
    24481 aatcagcaaa tctgaacctg agtcaatata attaatatta ttttccatct ccaacattgt
    24541 aagtactgtt ggtgttaata tagggacttt gtacaattgt atttttttga ttttatcatc
    24601 tgcacaaagg agatttttta aatctaatcc ttcttttatt tcaaaagttg aattttttaa
    24661 atctataaga gtaaaaccaa ttccttcata ctgaatttct gaaaatcgaa tttttctccc
    24721 agttgataga tcaaggggca gaaaaccttt tattacattg tgagtgtcac catcatttac
    24781 aatgtcatta ggaattttga ttttagaatt ctgtggagca cctattggaa gataataatt
    24841 cattataatt ttgtagtctt catgaggaaa taaagtactt ttaggattgc taagatattc
    24901 tcgtaccgaa tctaagaatg gcttatccat tgaatcttca tccccattta aactaaaaaa
    24961 cattcctaca attgcttttg caactctaag tgaattcatt ttctttattg aatgtgttaa
    25021 atcagactta ccattcttta aacttgtatt gttataaagg aaatttttat tgtcttctgc
    25081 aaatctaata tattcctcaa catactcact accaaaaaaa ctattacatt tactacataa
    25141 cgtattggaa tggcaacagt ttttttgaca aattttataa ggtgcagaac ttctttccgt
    25201 atgctattcc gattgtcctt gacaatgagc ctcctcggat gtgacgatct tcggcaggag
    25261 ctaacagtta aagttagact gcctcgctag cgttagcaca tccgagctca ttatcaagga
    25321 ttcgctgcgc caat
//
LOCUS       DAFLWC010000037        24506 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.038, whole genome shotgun sequence.
ACCESSION   DAFLWC010000037 DAFLWC010000000
VERSION     DAFLWC010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24506
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.038"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(207..914)
                     /gene="deoD"
                     /locus_tag="L1V17_001413"
     CDS             complement(207..914)
                     /gene="deoD"
                     /locus_tag="L1V17_001413"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBN1236190.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(931..1749)
                     /locus_tag="L1V17_001414"
     CDS             complement(931..1749)
                     /locus_tag="L1V17_001414"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBN1236191.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            complement(1773..2939)
                     /gene="deoB"
                     /locus_tag="L1V17_001415"
     CDS             complement(1773..2939)
                     /gene="deoB"
                     /locus_tag="L1V17_001415"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBN1236192.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            complement(3038..3994)
                     /locus_tag="L1V17_001416"
     CDS             complement(3038..3994)
                     /locus_tag="L1V17_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1236193.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            complement(3994..5127)
                     /locus_tag="L1V17_001417"
     CDS             complement(3994..5127)
                     /locus_tag="L1V17_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1236194.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            complement(5120..6682)
                     /locus_tag="L1V17_001418"
     CDS             complement(5120..6682)
                     /locus_tag="L1V17_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1236195.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            complement(6894..7976)
                     /locus_tag="L1V17_001419"
     CDS             complement(6894..7976)
                     /locus_tag="L1V17_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1236196.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            complement(8042..8440)
                     /locus_tag="L1V17_001420"
     CDS             complement(8042..8440)
                     /locus_tag="L1V17_001420"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBN1236197.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            complement(8461..9123)
                     /gene="deoC"
                     /locus_tag="L1V17_001421"
     CDS             complement(8461..9123)
                     /gene="deoC"
                     /locus_tag="L1V17_001421"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBN1236198.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            complement(9169..10470)
                     /locus_tag="L1V17_001422"
     CDS             complement(9169..10470)
                     /locus_tag="L1V17_001422"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBN1236199.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            complement(10611..11627)
                     /locus_tag="L1V17_001423"
     CDS             complement(10611..11627)
                     /locus_tag="L1V17_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBN1236200.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            complement(11935..12540)
                     /locus_tag="L1V17_001424"
     CDS             complement(11935..12540)
                     /locus_tag="L1V17_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBN1236201.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            12736..13659
                     /locus_tag="L1V17_001425"
     CDS             12736..13659
                     /locus_tag="L1V17_001425"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HBN1236202.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            13718..15283
                     /gene="guaA"
                     /locus_tag="L1V17_001426"
     CDS             13718..15283
                     /gene="guaA"
                     /locus_tag="L1V17_001426"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBN1236203.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(15774..17405)
                     /locus_tag="L1V17_001427"
     CDS             complement(15774..17405)
                     /locus_tag="L1V17_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HBN1236204.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(17419..19092)
                     /locus_tag="L1V17_001428"
     CDS             complement(17419..19092)
                     /locus_tag="L1V17_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HBN1236205.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSGMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            complement(19105..19422)
                     /locus_tag="L1V17_001429"
     CDS             complement(19105..19422)
                     /locus_tag="L1V17_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBN1236206.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            complement(19447..20847)
                     /gene="lacG"
                     /locus_tag="L1V17_001430"
     CDS             complement(19447..20847)
                     /gene="lacG"
                     /locus_tag="L1V17_001430"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HBN1236207.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            21084..21869
                     /locus_tag="L1V17_001431"
     CDS             21084..21869
                     /locus_tag="L1V17_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBN1236208.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            21872..22564
                     /locus_tag="L1V17_001432"
     CDS             21872..22564
                     /locus_tag="L1V17_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBN1236209.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(22838..23209)
                     /locus_tag="L1V17_001433"
     CDS             complement(22838..23209)
                     /locus_tag="L1V17_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HBN1236210.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(23609..23839)
                     /locus_tag="L1V17_001434"
     CDS             complement(23609..23839)
                     /locus_tag="L1V17_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236211.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            complement(23933..24271)
                     /locus_tag="L1V17_001435"
     CDS             complement(23933..24271)
                     /locus_tag="L1V17_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236212.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
BASE COUNT         7107 a         5445 c         4342 g         7612 t
ORIGIN      
        1 tcacaatatt catcaaacat gaaaagctgt tttttgaaat tgttccttgt gactcagagt
       61 taaacggcag attcacaacc tcttggtaaa cggtgttcaa aagcttacat ttgcaataat
      121 aagtccagcc aagtcaaaaa catgaggagc tatttttgct tggatgttct tattacttaa
      181 tgcagggcag ctttttcatt tccttcttat tctgctatcg ctgtttccaa tcctacttcg
      241 atcatttcat tgaacgtaga ttgacgttct gcagctgttg tttcttcacc ggtgatcaaa
      301 tggtcgctaa cggtcatcaa acttaatgtc tgcacatggt atttcgcgcc taagtaataa
      361 agagccgctg cttccatttc cactcctaaa acgccaagtt cagctaattg gaacgtctct
      421 gtcaaatcat ctttgtagaa agaatcttcc gaaagaacat ttcctacatg aaccgtatag
      481 cccttttctt tagctatctc atatgctttc agtaatagat tgaaatcact gattggagga
      541 aaatgaaagg cttggaaatt tttttcgatc atcgaagaac tggtcgctgc accttgtgct
      601 agtactaaat cacgaacatg gacgtctttt gacaatgcac cgcatgtacc tactcgaatc
      661 aatttcttta caccatacga ctggatcaat tcatgggcat agatggtggc tgatggcatt
      721 cccattcctg ttccttgaac agaaatacgt tctcctttat atttgccggt aaagcctaac
      781 ataccgcgta cctgattgta acaaactgga tcttccaaaa aagtctccgc aatatattta
      841 gctcgcaaag gatctcccgg aagtaaaatc ttatcggcga tctcgccttc tttcgcttca
      901 atatgcacac tcattttatt gttcctccta ttacaataat gtcaatgttt ctttaaccaa
      961 tgctttaaaa gattgtttga ctctctgagt tgtttctaca acttcttcat ggctcagatt
     1021 cgcttgcata cctgctgcta agttggtaat acaagagatt cctaacactt ttaatccgct
     1081 gtgagctgct acgatgactt ctggaacagt cgacatccct actgcatcgg ctcctattgt
     1141 ccgagacatt cggatctccg caggcgtttc ataagttggt ccagaatagc ccatatatac
     1201 gccttcttta agatccaaac ctagtttttc tgctgctgct tttgctgttg cttgatagtc
     1261 aggcgtataa gcttgactca tatctggaaa tctagggccc attgcatctt cattcggacc
     1321 gatcaaagga ttttcaccag taaaattgat atgatcggta atcagcatca aatctcctgg
     1381 tacaaatgat tcgttgacac caccacatgc attagtcaca atgactgaat gggcccctag
     1441 tccggccatc acacgtactg gataggtcac tgtttgcatg gaatgacctt catagtagtg
     1501 gaatctccct tgcatggcta acactttctt gcctgccaga gacccataaa ctagctttcc
     1561 tgcatgccca actactgtcg aaacaggaaa gaacgggatc tcatcataag aaatcattac
     1621 agcatcttcg atttcatctg ctaattcacc taatcctgaa cctagaatca aaccaaaatc
     1681 aatttctttt actcctttat caaggataaa ctgggtcgtt tcttgtaaca tctcgcttaa
     1741 cttggtcatt tgctttctcc tatttaaaaa gattatttta ataatttcaa gaagctttcg
     1801 ccattttcag tcgaagaaac actaaagttc tcagcaatcg ttgctgaaat atctgaataa
     1861 tatccttgag gcaatgcccc ttgttctttc atttttttac tgtaaaccaa taacggtaca
     1921 tattctcgcg tatgatcggt accagtaaac gtcggatcgt ttccgtgatc ggctgtaatc
     1981 attagcaagt cgtcttcttc catcgcttca agcaattctg gaattcgtaa gtcaaattct
     2041 tcaatcgcat gcgcatagcc gactacatcc cgacgatgac cgtataatgc atcaaaatct
     2101 actaaattgg taaagctgat tcctgaaaaa tcgtttttca taactttcag cagctggtca
     2161 acgccatcca tattgctttt cgtgcggaca gattcagtga ttccttgtcc gttgaaaata
     2221 tcgttgatct ttccaacagc aatcacgtcc tttcctgctt ctttcaaaga atcaaggact
     2281 gtgtgtccga atggattcaa cgcataatca tggcgattgc ttgttcgtgt gaagtctcct
     2341 ggttcaccca cgtacggacg tgcaatgatt cggccaatca tatacggatc atcttttgtt
     2401 atatcacgaa cgaattggca aatccgatat aattcttcta aaggaatgat ttcttcatgt
     2461 gccgcgatct gaaggacagg atcggcagaa gtatatacaa ttaaatcgcc tgttttcatt
     2521 tggtgttcac cgtaatcgtc aataacagct gttccgctat aaggtttgtt acatacgact
     2581 ttacggccag aaaattcttc gatttgtttg atcagatcat cagggaatcc attaggaaac
     2641 acacgaaatg gagttttgat attcaatccc atgatttccc agtggcctgt catcgtatct
     2701 ttccctacag aaacttcttc taatttcgtc gcatagcctt gatgatcttt cactgattcc
     2761 acaccttcaa gaggacggat cgttcctaaa ccaagctgct ctaaatgtgg aacgttcaat
     2821 cctgcttctt tcgcaatgtg tcctaatgta tcagaaccaa catcaccgaa cttatcggca
     2881 tctggtgctt ctccaattcc tactgaatcc atgacgatca gatgtacgcg tttaaacatg
     2941 attattcctt ctttcttttt atttttattg cctttaaaac aaaaagggcg agacgaaaaa
     3001 cacttcccgt aacccaccct ttttattcgc taaaagatta ttttgatttg atatagttct
     3061 tcccgtttgc ttttggacca gaagctttcc ctaagaaaac aaccagcaca atgattgtca
     3121 gcaaatatgg agcaatttgc agcaatactg gcggaatcga agaaataact ggtaattgtg
     3181 cgccaatgat actcaagctt tgagcaaaac caaagaacaa tgaggcaccc attgccccta
     3241 aaggattcca cttaccaaag atcatagcag ccatggagat gaacccttgt ccaacgatcg
     3301 taccagctga aaagttaccg gaaatcgact gagcaaaaac agcaccgccc ataccgccta
     3361 acaagccaga aatcagtacg cctgaataac gcatagcata tacattgata cctaatgtgt
     3421 cggcagcttg aggattttca ccaactgaac ggaggcgcaa gccgaatttc gtcttgaaga
     3481 tgatcaccca agctaggaca gcaatcaaaa tagcacaata agcaggtaag aatgtatttt
     3541 taaagaaaat tggtccaatg accggaatat ctgctaatcc tgggaaagaa aaatacccca
     3601 gattctgcgt gatgttatca gtttgacctt taccatacca tgctttgatc aagaaaacac
     3661 ctaaagcagg tgccatcaga ttaattactg tcccgctgat aatatggtca gcacgcaaac
     3721 tgactgttgc tactgcgtga atcagagaaa ataggatacc tacgacgcca cccactaaaa
     3781 tagcgatcca tggtgtcata gaaccaagtg atggactcat cgtcaagttg aaaacgatgg
     3841 aactaaaagc acccatgacc atgattccct ctagccctac gtttacgatc ccgcttcgtt
     3901 cagaaaaagt tccgcctagt gacgttagaa ttagcggtgt tgaataaacc agtgtagaag
     3961 taaggatcaa ggcaattaat tcgatagtcg acattatagt tcgccccctt catggttttg
     4021 attcgttggt ttcgattcta ttgtcgcaac gatctcttct tgttttttcc cttggaagac
     4081 tttagccatg acgaaacgaa tcaggaagtt gatcccgaca aagaagataa tcaaagcaat
     4141 cgatacattg acgatctcaa acggaacacc tgctcctgtc tgcatgccaa gtccaccgat
     4201 cttcaaaata ctgaacaaga tcgctgataa aagaataccg attgctgatc cagaaccaag
     4261 caaggaaaca gccattccgt caaatccaat agatagcgaa gtcgtttgaa caaagaagtt
     4321 ttgatacgtt cctaatcctt caaccacacc gccaagccct gccaaagcgc cagaaatgac
     4381 catcgacaaa acgatcgtac gtttactact cattcctgca tactcagaag caaaaggatt
     4441 caatccaaca gaacggattt caaatcctaa agtcgttttc ttcatcagca gccaaacgaa
     4501 aataagcgcg atgattgcta aaaataatcc tgagtttacg cgagagccgc caaaagcttg
     4561 tgttaaccat ggtaaccgca gtgaggcatt ttgactgatc atattggaag agtccaaact
     4621 tgagcgatag ctttcaggca tcacttcatg taaagcaaat gtgcttacgt ataataagat
     4681 atagttcatc atgattgtta cgatcacttc acttgttcca aaaaatgctc gaagtaaacc
     4741 tggaacagcc gctgccatcg caccagctaa ggcacctaag atcacgcata acggaagcaa
     4801 aacaactttt ggcagatctg gaaacgcaag tgccacccag acactgacga tccacccgca
     4861 aagtgcttgt ccagaaagcc caatattgaa aaacccagct gagttagcta cagaaaaacc
     4921 taatgctgta aaaatcaacg gcgttgcttg ccttaacgtt tcacctatcc ctctttgcga
     4981 accaagggct gcatctagca tagaagaata accttggatg ggctgaaaac caaaagcagc
     5041 catcaatatc gcgcctaaga tcaatcctaa aacaactgaa agtacaggca ctaataaatt
     5101 acggaatttt tcgctgcgat cattcatgtg cgccagcccc cttttctaac tcttttcgtg
     5161 cttcttctaa ggtatagccc gccatcaata gacctaattc attttcagat gtttctttcg
     5221 gatcaacgat accgacaatt tctccttcat ggataacagc aatacgatcc gaaacattta
     5281 aaatttcttc taattcgaaa ctgatcagta acactgcttt gtatttgtcc ctttgttcga
     5341 tcagacgttt atgaataaat tcgatcgcac ctacatccag tccacgagtt ggatttgcaa
     5401 caatcaacag atcaggatct cggtcgactt cacgagcgat aattgctttt tgctgatttc
     5461 cgcctgataa agcttttgcg ggaacaagtt cattcgttgt tcgaacatca tattcttcga
     5521 tcaattctct ggcatgttca ttcattactg aataattcag catgccgttt ttactgtaag
     5581 gtttttgatg ataggtttgt agtgcgatat tttcagataa tgtcatatct aggactaacc
     5641 cgtatttatg acggtcttct ggcacgtgtc ctacaccatg ttcagtgatt tttcggggtt
     5701 ttttattagt gatgtcttcc ccttttagct tgatatgtcc gctttctgcc tttcgcaaac
     5761 cagtcaaagc ttggatcaac tccgactgcc cgtttccatc gattccagcg ataccaagta
     5821 cttcgccagc acgaacctct aagttcaagt ttttcacggc ttctaatcca cgattttctt
     5881 tcaccactag attttcaata gacaaaacga cttcttgagg cttcgcttct tttttcatcg
     5941 ttttgaatga aaccgttctt ccaaccatca tatcggctaa ttgttgtgag gttacgtctt
     6001 taacgttgac tgtaccgatt ccttttccac ggcggataac tgtacagcgg tcagctactg
     6061 ctttgatttc atctaactta tgcgtaatca aaatgatcga cttgccttct ttgactaatt
     6121 ccttcatgat cacgattaat tcatcaattt cttgaggggt caatacagct gtcggctcat
     6181 caaaaatcag tacatctgct cctcggtaaa gtgtttttaa aatttctacc cgttgttcca
     6241 ttccaactga aatatcacga acgtaagcat ctgggttgac tgacaatcca tactgttcag
     6301 aaactttttg gatctctttt cgtgcttttt tatggtcaag catccctgcg cgactaggct
     6361 cgcttcccaa cacgatgttt tctgttacag taaaggcatc aacaagcata aagtgctgat
     6421 ggaccatccc aatccctaat tggttggctt tggtcggact tgtgatcttt acttctttcc
     6481 cacgcatcaa aattttccct gatgtcggct ctaataatcc ggaaagcacg ttcatcaatg
     6541 tagatttgcc agcaccgttt tctccaagca acgcatgaat ttctcctgcc tttacttgta
     6601 aattgatgtt gtcatttgcc ttgaatgttc caaattcttt ggtaatattc tgcatttcta
     6661 tgacaatatt ttcttgaacc accttttttt cacatcctaa cgatttctat ctagggcaac
     6721 gattgactaa gattcacgct tagtgagcgt tcttcttttg aaacaaacat tacttcaggg
     6781 agttgttccc ttatccaaac tgtcacaagg cagcttggat aaatgaacaa ttcttgttct
     6841 aatcaaacca tagccttgtc aaacatgtgt ctaacaaggc tatagaaatg gttttagttt
     6901 tcttcaggag tttctggaac ttttacgtca cctgaaatga ttttttcttt tgcttcatca
     6961 actgcttttt tcgcttcgtc agaaagttgt ccttctgtta gaccaacacc gtcttctttc
     7021 aatccataaa cagtgtgttc gccgccaggg aatttaccgt ccgctgattt ttgtgccaaa
     7081 tcttctacta ctgttccaac tgctttcagt gtagatgtca atgtgaagtt tttcttttcg
     7141 ccgtttaatg tgtattcgcc ttcgtctgat tggtcgcggt caacaccgat aacccaaact
     7201 tttttgtcgc ctgattcgtt caatgatttt gcttcttgga atacaccgtt acctgtaccg
     7261 cctgaagcat ggaagatgat atctgcgttt tgtgcataca taccttgagc aattgaacgt
     7321 cctttatctg gagcagagaa gtcaccagca tattgattca atactttgat ttcttttcct
     7381 aattctttcg cacctgcatc aacaccggct ttgaatccag catcaaaacg atcgattact
     7441 tcacctttta caccgccgat aaagccgact acgtttgttt cagtcgtata agctgctgca
     7501 acacctgcaa gataagaagc ttcgttgtct ttgaaagttg cagatacaac gttatctaat
     7561 ccatcgatga catcatcgat aataacaaag ttcgtacctg tattgtttgt tgcttgttct
     7621 tggatcgctg gttttagttt ataaccaata ccaaaaatcg ttttgaatcc agcattcaat
     7681 gcttggtcaa tatttgggat gtaatctgat tcatttgaag attggaaata ttggaagcca
     7741 tcatttcctc gtgaaagtcc ttgatctttc ccccattttt ctagtccttc ccaagctgac
     7801 tggttgaatg aacggtcgtc tacaccacct gtgtctgtga tcaatgctgc agttgttgtg
     7861 tctgatgagc ttttgccacc ggatgaatca gtagagccgt tgttgccgca tgcacctaaa
     7921 aataaccctg ctgctagtgc gacagcacct aaaccaaata attttgcttt tttcatttct
     7981 gtaaagcctc ctaaaataat tgttttattt ttcaacagtc agctgactga atgaacatga
     8041 gttatagatc tttttcagta aatgcataag gcagcagtgc acgaacggtc gttgccttcg
     8101 tcacaccatt gtctcctact agcgtaaccg gcatatcagg ggaacagaat tctgccatta
     8161 cttgtcgaca tgcaccacaa ggagagatag gatcgggggt gtgccccgct acgactagat
     8221 gcgtaaatgt tttttctcct tcagatactg ctttgaaaaa agctgtgcgc tcggcacaat
     8281 tcgttaatcc aaatgatgca ttctcaatgt tgatgccttg ataaatcttg cctgattccg
     8341 ttacgagaca agcgcctacc ggaaaatggg aataaggaac ataggcttta tctaacgctt
     8401 caatagctgt gttgatccat tcttgtttga gttctgccat gagcttctcc tttgaaaaaa
     8461 ttaatagcct tcaccagttg aaccagatac gattgctact cctgcgcttg ttccgattct
     8521 tgtagcacca gcttcgatca ttgccattgc ttcttcttcg ttatggatac cgccggaagc
     8581 tttgacaccc atttctggtc ctacagtttc acgcatcaaa cggacatcct ctacctttgc
     8641 tccgcctgtt gagaaaccag ttgatgtttt gacaaaatca gcgcctgcag cttttgctat
     8701 ttcgcaagct cggatgattt cttctctatc taataacgat gtttcaataa taactttgac
     8761 aagcgcacga tcttttgctg cttcaacaac tgcttcgata tctttttgga cttgttgatc
     8821 atcctttgat ttcaaagcac cgatattgat gaccatatcg acttcatctg caccgttatt
     8881 gatggcatct gttgtttcaa atgcttttgt ctcgggtgtg tttgctccta gaggaaaccc
     8941 gattactgta catacggcta ctggctcacc ttgtaattgt tctttcgcta gcgcaaccca
     9001 tgctggattg atgcagacag aataaaaatg gtattttttt gcttcttcga taatttgcat
     9061 cacagcttct ttagatgcgt ctgctttcaa aatagtatgg tcgatcattc ggtttagttc
     9121 catttctttt ccccttttct ttaaaacggt aaagtccgct tttttccttt attctgtgat
     9181 gatgtcatga atcaacgttg gcttcattgc cgattcacca atttcaatat ttttatataa
     9241 taattcaatg acagaagtga tttcttcgtc gttactatag atcgtcaata gtgactcacc
     9301 ttttgtcaca gtgtcaccaa tttttttatg cagtttcaat ccaacagcgt gatcaatatc
     9361 ttcttctttg gttttacgcc cagcacctag catcattgca gcaattccta attcatttgc
     9421 cacgattttt gacacaactc cgctttgttt agcaggaagc tccattgtgt agcgtgcagt
     9481 caaaattcgt tctggatgtt ccacgatcgc tgggtctccc ccttgatttt ggatcatttc
     9541 tttgaatttt gctaacgctt tacctgattc cagagcttct tgaagcaacg ttcttgcttc
     9601 atcggttgtc ttagctttgc cagcaagaac aaccatttgg cttcctaagg cgtagcacat
     9661 ttctactaga tcttctggac catttccttg taatgtttcg attgcctcga caacttctag
     9721 actatttccg atagcttcgc caagaggttc tgacatatct gagataaccg ccactgtttc
     9781 tcggttagcc agtttcccaa tgctcgtcat ggtctttgcc agacgtcttg catcttcgat
     9841 gttcttcatg aaagcaccgt ctccagtggt cacatccaaa acgattgcat ctgctcctgc
     9901 cgcgattttt ttactcataa tcgaactggc aatcagcgga agagaatcaa cggtcgctgt
     9961 gacgtcacgc aaggcataca attttttgtc cgccggtgcc aagtttcctg attgaccaat
    10021 taccgctact ttactttcat taacaatgcg tacaaattct tcatccgaaa gctcgatctg
    10081 aaatccggga attgcttcta gcttgtctag tgtaccacct gtgtaaccta gaccgcgtcc
    10141 agacatttta gccactgtca ctccgacact agctactagg ggggctaaaa tcaatgtggt
    10201 cgtgtcacca acgccacctg tcgaatgctt atctaccttt attccttcaa gagaactcaa
    10261 atcgatgaca tcaccagaat tagcaatcgc caatgttaag ttcgtgattt cttcatttgt
    10321 catgtcttga taaaaaattg ccatcaataa tgcactgact tgataatctg gaatctttcc
    10381 attcgtatag ttcgtgacga tgtactcgat ttcctctttc gacagctcgt ttccatccct
    10441 ctttttttca atcagatcca ccattcgcat tgcctgatcc tccttgtctt cattcggtat
    10501 tatacattat ttttaggaaa ggtaaaccac tttagtaaac tggtttacta aaaataaaaa
    10561 aagcactaac tagcctttgt aaatgcttac ataagcaata taccgccgag ttagcccttt
    10621 gtcaatactt ttacgctctc acgaataatt aattttgttt cgaacacttt gttcggaact
    10681 tttctttgag gaaattcgat cgtatcgatc aggaaacgtg cagcataaaa tccaatatca
    10741 aaacttggct gctgcactgt cgtcaattgc ggaatcatgt attctgacag ctttaatcca
    10801 tcgaatccta tgactgagat atcttctggg atttttttgc ccaattcatc gatcgcctga
    10861 tagcatccga tcgccatggc atcattcccg caaaaaatag ccgtgatatc tttatgtttg
    10921 agtaattttt ttgatgcagt atatccacct tggacagtca actctccatg ttcaacaaat
    10981 ttcccattaa aaggcaggcc atgatctttc agcgcatgac gatatccgtt gaaacgttct
    11041 tctaattgat agtatccagt ggtttccttc agcatgccga tcttcgtatg gccattttca
    11101 ataaacagcg aaacagcttg ataggcgccc tcatattcct ttacgataag ccgtccgtta
    11161 tcccgacgat tcaatccgcg atcgattaaa atgattggca ttttttgata aaaaccgctg
    11221 tctaatgcat atttctcagg taaaatattt ggtgtggcca gcaagattcc gtccactgag
    11281 cggtgggaaa gctcttgtaa atacttgatc tcattttctt ggctatgacg agaattgcat
    11341 aacatgatca catagcccaa aggattcaaa tagctctcta caccttcgat cagtttggag
    11401 aagaagaaat cagtgacatc agggacgatc attccgatgg tctttgaatg tcgattgatc
    11461 acatttgaag cgaaataatc gggcttataa tgatgttcat tcacgatcga caacactttt
    11521 tttcttgtct tatcactaaa tctgcttcct ttgttattca aaatctgtga gacagttgtt
    11581 actgatacgc ctgccatttc tgcgatatct ctgatggtca gcttcatcct attggctccc
    11641 ttctatctaa attccctatc agtgtaccaa aacccccaag aaaagaatag agaaaaaagg
    11701 aaagtatgtt ttttgataaa aacctccttt atctaccgac ttggcagcct tctatacaag
    11761 ttctgtatct tatttatttt atcgtaaaaa acaacgactc tgttcctact atttcttttt
    11821 gaagaaaaaa tagttctttg tttttaaaaa cttctcaaca aaaaaagaac tgatacgtac
    11881 ccgtacatgc acgcccagtt ccactctttc gtcgctccac tatttttcag ctagttattc
    11941 tttcacactt ttgatgatat aatatccttt atcttttgtg acgatttctg cattaccaaa
    12001 tgtttcttcc attttctttt gcgcactcgg cgctccttgt ttcttctgga tcacaattgt
    12061 cagtgtaccg cccttcttca accgaggata tgcgcctgtc aaaatttcat gtacaacttt
    12121 ttttccagca cggatcggcg gattgcttac gatagctgca taggtttctt catgaactgc
    12181 ttcatagata ttcgattgat ggatatcaac atgttcgatt tggttacgct ttgcgtttcc
    12241 ttgcgctaga cttaccgctc gttcattaat gtcgaccatt tcaacaaacc gctgtgtcgc
    12301 aaatgccaaa gctaacccaa tcggtccata cccgcatccc acatctaaga tctttccttc
    12361 atcaggtaac tcttcccaat cgaaagcatc aatcaggaca cgtgaaccat aatccactgt
    12421 ttcacgtgaa aatacaccag aatctgttac aaattgaaag gttctgcctt ttaactcaaa
    12481 agcccattgt tcaaaatcgt gcgccgtatc tgggcgttca gaatagtaat gatttgtcat
    12541 gtcttccatc cttctcattt ctttcatgac aacagtctat ccttttatgt atccgtgcgc
    12601 aagtcaagaa taagactccg tttctttcta ttataaagat tatacaaaaa gatcggcaat
    12661 ctctcttaag tggtggggtt tgcgtttatt ttgtgttaaa atagttccat tgatgggaga
    12721 acgcaggagg ctaatatgaa tgatccaatg aactactacc gtgtggcaag agaagaatgg
    12781 cgagaatttt atcgtaatgg gcaagcacct ttgacacaag atgaactaga taatatcaaa
    12841 agtttgaatg accgcatttc catgcaggat gttcgagata tctatgtacc tcttgctcat
    12901 ctgatttatc tttatatgaa agaatttgaa tctttgttct tgagtaaagg tttatttctt
    12961 cataaatacg tagaagtacc gccttttatt atcgggatcg ccggaagtgt agccgttgga
    13021 aaaagtacaa cagccagact gctgcagacg attttgtctc gtaccttcaa acgaagaaac
    13081 gttcagctga tcacgactga cggatttctt tatccaaatc gtatattaaa agagcgtgga
    13141 atcatggacc gtaaaggatt tcctgaaagt tatgatatgg agatgctgat cgatttcttg
    13201 aaccgtgtaa aatctggtca ggaagagata aaagtacctg tttactcaca tgatgtgtat
    13261 gatatcattc cagacaagta cgaattgatc cagcagcctg atatcttgat cgttgagggg
    13321 atcaatacgc ttcaattacc tgcgaatcag caaatctacg tcagcgactt ttttgatttt
    13381 tctgtctatg tcgatgccga tcccgtgctg atcgaaaaat ggtatttgga tcgttttggt
    13441 gcgttactgg atacggcttt ccaaaatcca gagaattatt attatcgttt tgctatcgga
    13501 gatcgtgaag aagcctttaa aatggcaaaa gatgtatgga aaaatgtgaa tttgaaaaat
    13561 ttacaggaat atatcttgcc tacacgagga agagccgata taattctcca taaaactgaa
    13621 aatcatatca tcgattcgat tttcatgcga aaatattagc attttaaaat agtttgacta
    13681 ttttgagata aaatttaaag ggataggggt aataaatttg acaaacgttg ccgatatgac
    13741 gaacgttgaa aagattatcg tattagacta cggtagtcag tataaccaat tgatcacaag
    13801 acgtattcgt gatcttggag tcttttccga attattgagc caccgcatta ctgcagaaga
    13861 agtaaaagcg atgaatccaa agggaatcat tctttctggc ggaccaaaca gtgtatatga
    13921 tgagaatgca tttgggatcg atcctgagat cttcaattta ggtattcctg tattagggat
    13981 ttgctatggt atgcaattga tcacgtacaa acttggcggt tccgtagagc ctgctaaaaa
    14041 ccgcgaatat gggaaagcct tgttagaagt aacaagcgat caagctgtct tgtttaaaga
    14101 aacaccaaaa caacaaacag tatggatgag ccatggtgac ttggtaacta aagttcctga
    14161 aggctttgaa acagtcggaa caagcaaaga ttgtccgatt gcttctatcc aagacacaac
    14221 acgtaatttt tatggtatcc aattccatgc agaagtacgt cattccgaat acggaatcga
    14281 attgctgcgc cactttgcct ttgatgtttg tcactgtgaa ggtaactgga caatggataa
    14341 ctttatcgat atgcaagtag aaaaaatccg tgaacaagtt ggtgacaaaa aagtcttgct
    14401 tggtctttca ggtggcgttg attctagtgt cgttggggtt cttttacaaa aagcgatcgg
    14461 tgaccaattg acatctatct ttgttgacca cggtctgcta cgcaaaggcg aagcggaaca
    14521 agtaatggaa agtctaggcg gaaaattcgg cttgaacatc atcaaagtca atgcaagaga
    14581 tcgcttctta gacaagttga aaggtgtatc tgacccagaa caaaaacgta aaatcattgg
    14641 gaatgaattc gtatatgttt ttgatgacga agcaacaaaa cttgctggtg aagaaggcgt
    14701 ctctttccta gcacaaggaa cgttgtatac tgacgttatc gaatctggta cagaaacagc
    14761 acagacgatc aaatctcacc ataatgtagg tggactgcca gaagatatgc aatttgaatt
    14821 gatcgaacca ttaaacacat tattcaaaga cgaagtccgt gaattaggga ctcagttagg
    14881 catgcctgat tcaatcgttt ggcgtcagcc attccctggt cctggtcttg gtattcgtgt
    14941 tcttggcgaa atcactgaag acaagctaga aatcgtacgc gaatctgatg ctatcttgcg
    15001 tgaagaaatc gcagctgctg gacttgaccg tgatatctgg caatatttca ctgttcttcc
    15061 agggatccgc tctgtcggtg ttatgggtga cggacgtact tacgactaca cagtcggtat
    15121 ccgtgctgta acttcaatcg acggaatgac cgctgacttt gcccgtatcc catgggaagt
    15181 cttgcaaaaa atctctgtac gtatcgtaaa cgaagtagcc cacgtcaacc gtatcgtgta
    15241 tgacatcact tctaaaccac cagcaacagt ggagtgggaa taaagagcca acataatatg
    15301 gagggggaat ccctataaat caacattctt caatagctaa aatgcttgat tttcattaaa
    15361 aataagatgg ttccctacca aaagagacta taatataagt taatttgttt cattcttatc
    15421 ataaaaagaa gttctcgaaa aacgaactgt tttccgagaa cttttttcta tccatctaag
    15481 tgctcaaatc atattcacga cggaattcta aggttaccct ttcttaaaca aactttatgt
    15541 tatctgcaca actttttgca attttttcat tgcttcttac gaaatcgttg aactctcttt
    15601 agcataatac aaagtgtaga tgaagtctgg tgctttactc gttttggtaa aaatgactgg
    15661 aaatcgtttc tggttatttt tggcaaaggc gaggtgcagg ttcgattcct gccttctacg
    15721 ctaacgatgt ggctgaaggg aacctccgat cttgaatcga aacgatccgc agtctattgt
    15781 ttcaccaatg aaacaaaatc aacgttcgtc caagcatttc ctgaagcctt gctataaacc
    15841 ccaatttcac aaacacctgt tgtaattgga atgtctttga ttgtaatttt tgtccattca
    15901 cttgttttaa caaccgcagt atttagttcc gctccaccat aatttttgat atataactga
    15961 ttagtatcaa actctccccc agacattaca taggcactca atgtgtaagt tcctttgctt
    16021 atgccactaa cattttgata agctgatgcc tcgtatgctt gatcctgcca aaaagttagt
    16081 ttgtagtccc caaaaaaagt gcccgcttcc gttttgatcg tacccttagc ggttccttgt
    16141 tgaaaccagg tttgccaatt ggaaggactg gtcgttggtc catcgctttc gaaacttgca
    16201 tttttaacta gatttatttg cgcccctgct tgtttaaacg cacgcaagct tggcaaggcg
    16261 tttccagcaa aatcaaacat cgcttggttg tcccattcgt ttcccatagt ggattgaaca
    16321 ctgagataat tcatacctgc ttgtgttgcc caactcacat ttccgttgta ccaaagaggt
    16381 tcccaataga agaagcccgc cccgcgatta ttcggtactg cctgaatccg atcggcaaga
    16441 tccagcaaat actctgcttg tcctgtcggt gttggttcat atccccccgc agctgcttcg
    16501 gcttcaccaa aagcatttgg catagtatcg gcattcgctg ttgtatgccc ataagctgtt
    16561 tcaactacga tcacttcttt accataccgt tggctgatcg cattcatatt ggtttgaagt
    16621 tcattcattg aaccgtgcca atacggataa tacgacactc caattaaatc aaatgacaca
    16681 cctcgactcg tgatttcatc aaaccaccaa gtaaatgctc ctgtatcgcc accatcagct
    16741 aagtggagca ttactggagt tgttttaggt tgagtgtctc gaacagcttg gataccagac
    16801 ttcaaaaaag cagccaatcg atcaaattct cccccgcctt ctccccaaga cttgccataa
    16861 ggccagagca ttccgctatt cagttcattg ccgatctgaa ccatatcagg ataaacgtcc
    16921 agctgcttca tttccgacag aacgttcttt gtatagtcgt acaatgccgt attcatttct
    16981 tcaaaggtca gaccttgcca tgctttagga agattctgtt tcccaggatc aacccaaaaa
    17041 tcactgtagt gaaaatccag cagcacctta agtcccagat tttttgctcg ttttgcaagg
    17101 tcaatcgtcg tttccagatc atttgtccct gctccataac tttctccatt actattataa
    17161 ggatcctgcc acaaacgcag tcgaacatag ttgacaccat tattttttaa aatctctaag
    17221 gcatcttttg aaatatcgtc ttcataatat tttgcaccag atttttccat atctgacagg
    17281 atcgaaatat ctgctccgcg aataaattcg ctggcagatg cttcaacagt ttttgaaaca
    17341 gcccccaaag cccctaacac agctgcaaat aaaacagctt tacgcaacca aattcccatt
    17401 ttcattatgg ctcctccttt attgaaattg gttcagaata aactgaacag ctttttcagg
    17461 atctctcgtt aatccgatat attctgctcc ttttgtcgca accagcttga ttcctaagcg
    17521 atcggtgtct tctttgatat catcatagta agaattgact tgcggtgcta agaccaccat
    17581 atcaaaatcc tgcagcattt cgtaatgaga accataagca cccgccattg cactgatcgg
    17641 tgctttcgat tcagatgcac ctttttttaa agcattagct aacatcccac ttgtccctgc
    17701 gccagcacaa agtaccaaca cattgatttc tttatttgca tcgctgataa cttgactcgc
    17761 tgccacaggt acttcctcac gtacatcggc agaagcacct tcctcggttg cgatcacctc
    17821 tgctttttgt gcttctttct ctactaagac agcatcgtat gctttgcaaa atggtagata
    17881 gatcaggaag tcaacgacga ttagaaccgc tgctagaaca aaagctaaga tacccatgcc
    17941 cgttcctaga accaaaccga tcggtgctgg agttgcccaa ggcaaaacgt acataaagct
    18001 gttcatgccc aatacatcga caaaaaactt gaacaggcaa acgtttacaa caggtgttaa
    18061 caaaaatgga ataaaaaaat aagggttcaa aatcatgggt gccgcaaata gcaatggttc
    18121 gttgacagcg aaacttactg gaataaagga agctttccca actgccttca actgcttaga
    18181 cttagcaaag agtaggaaga taaaaggaac aaccaatgtt gccccagttc ctcccatagt
    18241 tcctacaaaa ttccctaaac ccaccgtcag tactttagaa gcttgttcac cggaattgaa
    18301 caattgcaga ttggtttcca cattggcata gataattgcc gcaattgccg gctccacgat
    18361 cgacggtcca tgaacaccga caaaccaaaa cagcgccatc gctccccaga taatagcgat
    18421 tcctaagtac ccgtcagctg ctgtaaatag cggctgcagc accgtaatga ttgcttctgc
    18481 aaatgagatt tggaagattt gtcgaatgcc taaatcaatt aaaacggccg caaatactga
    18541 aaaagagaaa ggaaaaatat ctcggaaggt ttgcgaaatc gttccaggaa cttctttagg
    18601 cattttaatg gtaatatctt tcagcacaca aaacttatat aaattaactg ttaaaaatgc
    18661 agcgacaaag gaagccagta gtccctttgt ccccatatat tccgttgaaa atccaccttc
    18721 aatcggagag acgcttaaca acaggaaact taccacagag gccagcatca cagaggtggt
    18781 gttgattact ttgtttttcg gtaagcgacg attcatcgaa tcagccaagc agcgagcagt
    18841 ggttgctgaa acgagtaacc ctacaacacc catcgaataa ttatagactt tccatagcca
    18901 tgtggagaca gattcaggcc attggtaacc aaaaatctca ggaaccgcag caatcaaaat
    18961 gaaaatgctt gaaaataaaa tagctggcat cgctgttaaa aatccgtcac gaacggctcc
    19021 taaataacta ttacgtgaga ttttttcaaa aaatggtttc cctttttcga tttgtttaat
    19081 gattccatcc atagcgttct tctcctatcc ttgattctgt ctgtacagta caataaagtc
    19141 ttgaatcaga tctctcagca ataaagtggt cattaaatga tcctgcccat ggataaaaat
    19201 gaatcccatc tccatctctt tcccagatgc ttcttccgct aaaatttttg tttgcgaatt
    19261 atgtgcaagg gttaaatttt cgtcggcttc tttcaacgcc gaatcaacat gttcaaagtt
    19321 tccttgtctt acttctttca ataatttcaa taatgtactg cgagcgtcgc ctgaatatgc
    19381 aacgatctca aaaccaagca tttgtaattc ctctttattc atcttttctt cctccattat
    19441 cacttattaa ataatcgttt tggtttcact gaccaacttg taccagtaag ctgattcttt
    19501 tgggtaacgc ttctgggttt caaaatcaac ataaaacaag ccataccttt tgttataccc
    19561 atttgtccat gagaaaagat ccataagcga ccacaaaaaa taccccttca catttacccc
    19621 ggctgttatc gccttgctta aggattccaa atagactctc aaatagtcga ttctcggctg
    19681 atccataata atgccatctt caaactgatc tttatacccc atcccgttct cagtgatata
    19741 gattttgttg taatgtgggt aatcgctttt aattcgcagc aacaagtcat atagaccttc
    19801 tggataaatc agccagtccc aatcagttcg aggaattcct tctttataaa tacgttctcc
    19861 gattcccttc actttataaa cagaggtccc tttttcaccc gtaccgttat gatggattgc
    19921 attttctcca tcgtaagctt tgacaaaatg gcattggtag tgattgatcc ctaagtagtc
    19981 attacgcgtg gatgcttttt tcaattcaac gaaatcttct tcaggaaaat gatagctggc
    20041 ctgatttgct tcacatatct catcaagagc agtcaaggtt tcagttgaat aatagcctaa
    20101 ataggtagca tctaataaga aacggatcga caatgcatcg tctaaaaagg cagcatgctt
    20161 atcttccggc gcgtctgttg ccgcatattt cgtctctaat gagtgaacta caccaatttc
    20221 acccggaagt tcgttttctt tgaaatagtt cactacacgg gcatgagcaa ccatcatatt
    20281 atgaagacag gcgacgatct ttgtaaaatc atatttgatt cctggtggga aaacacctaa
    20341 caaatattga ttggttgcaa ctggatagat ttcattaaag gtactccaca ccttgacttc
    20401 tttgaattca tgaaaacaaa aaatggcata ggaaacaaat gcttctattg tttctcgatt
    20461 caaaaaatct ccatggtcaa acaaacgttt aggggtatca aaatgatgca acgtcacaaa
    20521 cggcgttacg tttcttttct tacattcttc gaacacacga tgataaaaag cgattccttc
    20581 tggatttggt ttcccagctc catcaggaaa aatgcggctc caagcaatgg ataatcttag
    20641 accatttaca ccaaaacgtt cacacaattc aatgtccttt gcatattgat gataaaaatc
    20701 acttgccgga tcgggactga atcgcccttg ttcctctaaa aagtcatccc aagcaacagc
    20761 gcctttgcca ccttccttag tggctccttc aacctgatag gctgctgtgg ctccgccaaa
    20821 aataaaatct tctggtaatt taagcatgta catctctcct caaatctata atcagttttc
    20881 gctctttcta actgattgca ttgtaaacgc atccaaaaca tttgtcaaca aaaacaaaca
    20941 caaataatca taaaaaccag aaaacagcaa taaaatctat tgtaacaaac ataaaaacca
    21001 ccctaaatgt ttacttttgt tcgaattaga ttgactgttg tccgtttata tgatagatta
    21061 tccttaaatt agaggtgaag acaatgttga aaaaagaaag attgcttact atcgtagaaa
    21121 tggtcaataa aaaaggaatc cttaccgtta atgaaatcat caatcaatta gatgtttctg
    21181 atatgaccgt tcgcagagat ttagatgaat tagaaaaatc gggcaagctg ctgcgtgtcc
    21241 atggaggggc tcaaagtctt tcctacactt tagatcaaga actttctcac actgaaaaag
    21301 ccactctgca gattcaagaa aaaaaagaaa ttgctgccac agcagcctcc ttgattcacg
    21361 agggagaaac gattttctta ggaccaggta caacaatcga actattggcg acgcatttac
    21421 tgaacaagaa aattcggatc attacaaata attatccagt ttttgatatt cttgctcaag
    21481 cagatggacc agaaattcta ctgattggcg gtgatttccg gaaaaatacc ggcgcatttg
    21541 tcggaccgat caccaacgac aatttaagaa gactaaagtt tacaaaagca tttatcagtt
    21601 caaatggcgt tcacaacgaa gcgatctcta cttacagtac cgaagaagga gaagcacagc
    21661 agatcgctct aaataattcc cgtaagaaat atctactcgt tgataataaa aaattcaatc
    21721 gagatgattt ttatgtgttt tataatttgc atgatttcga tctgctcatt acggatcgcc
    21781 agatctcgcg ggaggttcaa gagcactatg cacaatatgt cgatctgcaa attgctgatt
    21841 caaccgaaaa taccactata ggagcgtaac tatgaaaggg attatatttg atttcaacgg
    21901 aacaatgttt ttggactctc atctgcatga agctgcttgg ctgcatatga tacatgatca
    21961 tacaaaagat ggtttatcag acgaggatat tttaaaaaat attcatggtc ggacgaatac
    22021 ggagattttg aaacatttca tttcagagca tttgaccgcc tctgagatcg ccgtattgtc
    22081 agaagaaaaa gaaagctatt atcgtatgct ttgcttgcaa aatgaaaacg agcttcagtt
    22141 gacaaaaggg cttgaagcga ctcttgacca gctgactgac caacagattc cattaacgat
    22201 tgccacggct actgtcaaag agaatgttgc tttttatttt gatattttcg atttagcccg
    22261 ctggtttgac tgggacaaga ttgtctatga cgacggctct ttccctggga aaccgcaacc
    22321 ggatattttt cttaaagcgg cagacaaact gagcttagct ccggctgatt gtcttgttat
    22381 cgaagatgct tactcaggat tacttgctgc caaacgtgcg gggatcggaa caattattgc
    22441 aattgatcca ttcggtaaaa acaaaacagt atttgaacag gcacagctaa ataaagatgg
    22501 aaccatcaaa gattttactg gtttttggac agagcacctg tctgccacat ccgttaattc
    22561 ttaaacgatt caactaacta ccaaagaaaa gcaactgaaa tgcacacctc cttttataaa
    22621 aaactgccag tgaaacgaca tgaaagatac actgctatat ccttagtgaa atatagcagt
    22681 gtatctttga ctttttcatt cttttaacca tatgacgcgt tcatctctat ctataattaa
    22741 cattaaaaat agtgttttca cattatttct caaaccaatc ttaaaaatca tcaggagtac
    22801 ttttttgata tacttttatt aatgctgggc gtaatggtta aaagatttcc actagttcct
    22861 ctccaccaag ctgagttgaa aaatgcttat ctgtaaacaa catagacaaa gaggaaataa
    22921 acgtttccgt atctttctct gtcccaagga tattaattaa ttttcctact aggtaagtat
    22981 cattaaactt aagatctgcc ttcacatcaa aagttttgat aaaagctttt atcatgcgta
    23041 caattttgtc tttatcgcca taattgattt caccactcat atcaatatag tcactaatcc
    23101 ctgaagaaat aatggcaact gcttcttctt tcgccttatc agataattca tttaatgact
    23161 gggattgatt gatgacttct tgagttttat ctgttacgta atctctcatt atcctatcgg
    23221 catactccgc aaagtaatct tgaaaaaatt cttctacagg gtaaccaact tcgttttccc
    23281 aaccaggaga aatttcatta tcagtactta ttaaatctat taaaaaccaa cccgttctct
    23341 gagtgttgat tctataatat ttttaatttc ctatataaat caaaaatatt atagaatcaa
    23401 taagctaatt aagaaacaaa ctttagaaac tctagaagaa cttctgaatt tatatagaag
    23461 tgtgtagcta cttactaaat atacaaaagt taaaataaaa tactctggat actctttata
    23521 ctgcattaaa gttagtaata ttaacagcaa agatatcgaa aaaacaataa cataatatgt
    23581 gtcaaaattt ttcataataa gaactccctt actgttgcat actaacataa tccaaaaact
    23641 cttctacttc agctaaagac attccacttt ctttagtcca aaaaacagtt ttttctatcg
    23701 atccttctct gtaaactgta aatgtcggag tcgagttaat tgagtagcga ctcttgaatt
    23761 ctttccactc attttcatct tctctaactt ttgctacatt cacgtaataa atattttctt
    23821 ttcccttttc taccagcata tcgaatagct tcctgctttt gatgatcgat ttcttgtgct
    23881 acatctagta aattttcatc aatttctata tcataaagta tttcactagt gtctacatcc
    23941 acaatatata ctttttatca gtagcaattt ttgagtaatc cgttaaaatg atctcagtct
    24001 cgtcactttc atcagtataa atatacgtta acaatgaact caccttttca atcggtgtta
    24061 gctctaagcc tactgtattt tttactattg agtcattatt taccaccata acttcgtact
    24121 gtatatacca tcctatttgg tttccatcaa tatcagtaat tggctcacta gctaatggag
    24181 tctccggaac aatattttcc tgatatttct taaactcttc tgtagcacga aaaaggttat
    24241 catgttcctc acttgaaact ggttgagtca tagaaaatgt tacttggcta aacagaggga
    24301 aaataaacac tacaatcaac aaagtataaa aaaaagccct tctttttcat tttttatctt
    24361 ccaatcacaa attgaaaaac ttattcctgc aactttgagt ctagtatcac aatcgactga
    24421 ctacaactat tcatttacat tctactttaa gttcctcctt aaccattaat tttattaaag
    24481 atacttgtaa tagtgattct cacaaa
//
LOCUS       DAFLWC010000038        24293 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.039, whole genome shotgun sequence.
ACCESSION   DAFLWC010000038 DAFLWC010000000
VERSION     DAFLWC010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.039"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(547..909)
                     /locus_tag="L1V17_001436"
     CDS             complement(547..909)
                     /locus_tag="L1V17_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236213.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(983..1363)
                     /locus_tag="L1V17_001437"
     CDS             complement(983..1363)
                     /locus_tag="L1V17_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBN1236214.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1427..2620
                     /locus_tag="L1V17_001438"
     CDS             1427..2620
                     /locus_tag="L1V17_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBN1236215.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            complement(2697..3281)
                     /locus_tag="L1V17_001439"
     CDS             complement(2697..3281)
                     /locus_tag="L1V17_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBN1236216.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            3482..4480
                     /locus_tag="L1V17_001440"
     CDS             3482..4480
                     /locus_tag="L1V17_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBN1236217.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            4592..5101
                     /locus_tag="L1V17_001441"
     CDS             4592..5101
                     /locus_tag="L1V17_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HBN1236218.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(5131..5790)
                     /locus_tag="L1V17_001442"
     CDS             complement(5131..5790)
                     /locus_tag="L1V17_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBN1236219.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(5792..6556)
                     /locus_tag="L1V17_001443"
     CDS             complement(5792..6556)
                     /locus_tag="L1V17_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HBN1236220.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(6564..7241)
                     /locus_tag="L1V17_001444"
     CDS             complement(6564..7241)
                     /locus_tag="L1V17_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HBN1236221.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(7278..8663)
                     /locus_tag="L1V17_001445"
     CDS             complement(7278..8663)
                     /locus_tag="L1V17_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBN1236222.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSCLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(8873..8957)
                     /gene="ffs"
                     /locus_tag="L1V17_001446"
     ncRNA           complement(8873..8957)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="L1V17_001446"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(8980..9495)
                     /gene="tadA"
                     /locus_tag="L1V17_001447"
     CDS             complement(8980..9495)
                     /gene="tadA"
                     /locus_tag="L1V17_001447"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HBN1236223.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            9601..10458
                     /locus_tag="L1V17_001448"
     CDS             9601..10458
                     /locus_tag="L1V17_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1236224.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(10539..10874)
                     /locus_tag="L1V17_001449"
     CDS             complement(10539..10874)
                     /locus_tag="L1V17_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236225.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(10941..12311)
                     /locus_tag="L1V17_001450"
     CDS             complement(10941..12311)
                     /locus_tag="L1V17_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBN1236226.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(12389..12925)
                     /locus_tag="L1V17_001451"
     CDS             complement(12389..12925)
                     /locus_tag="L1V17_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1236227.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            13234..14715
                     /locus_tag="L1V17_001452"
     CDS             13234..14715
                     /locus_tag="L1V17_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1236228.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLIKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            complement(14818..15525)
                     /locus_tag="L1V17_001453"
     CDS             complement(14818..15525)
                     /locus_tag="L1V17_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBN1236229.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(15604..15942)
                     /locus_tag="L1V17_001454"
     CDS             complement(15604..15942)
                     /locus_tag="L1V17_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBN1236230.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(16053..17015)
                     /locus_tag="L1V17_001455"
     CDS             complement(16053..17015)
                     /locus_tag="L1V17_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HBN1236231.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(17030..18361)
                     /locus_tag="L1V17_001456"
     CDS             complement(17030..18361)
                     /locus_tag="L1V17_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBN1236232.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(18369..19049)
                     /locus_tag="L1V17_001457"
     CDS             complement(18369..19049)
                     /locus_tag="L1V17_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBN1236233.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(19268..19747)
                     /locus_tag="L1V17_001458"
     CDS             complement(19268..19747)
                     /locus_tag="L1V17_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HBN1236234.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            complement(19874..21553)
                     /locus_tag="L1V17_001459"
     CDS             complement(19874..21553)
                     /locus_tag="L1V17_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBN1236235.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            22101..23603
                     /locus_tag="L1V17_001460"
     CDS             22101..23603
                     /locus_tag="L1V17_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1236236.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            23616..24278
                     /locus_tag="L1V17_001461"
     CDS             23616..24278
                     /locus_tag="L1V17_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1236237.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
BASE COUNT         7273 a         4979 c         4114 g         7927 t
ORIGIN      
        1 gagtgtttcc cgattcattt ttggctgccg tagcaacttt tatatcatat cagagagaca
       61 agcgattgtc aactcttttt taaaagtttt tttcgatttc gtttttcgaa atctttcggc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcgt
      241 tagtaacatg tcaataacta ttttttaaat tttttagaaa tgtgatataa catccacttc
      301 agaatcaacg ctgttaaatt tatcatgtat ttcttccttg gtcaactata aattaagcat
      361 tactttgtga aatgattttt cgatcaatta ttattattcg ttatacaacc gttttcaaca
      421 tattttgaaa ataaaatgca ctaaaaaact atctttagca gaacatttca ttgtattttt
      481 tggaccaaac aataaaaaaa gaagtttgaa aaaaattcaa acttctttgt tcgcttaatc
      541 tgtattttag aagaaaggca ctccctctac ttcgtaagtt ccaagaacag agcgcatttg
      601 acctggttct tcccaaatat atccttcgcc taattcttct ctttgattct tttgttcagt
      661 ttcaaagaca aacaacggaa cattttcctc tttaatatgt gtatttgtca attccatcaa
      721 actaatcttg ctaacatcga tatgaactat ttcttttaag aaattaagta tattcgctaa
      781 accagtcttt ccttcagaaa gttccgctaa cgcaaattcc aacttgtcat caattgaatg
      841 gaccaaaaat tttttagtac catcctccaa atgcaacata attgtaccag caactctttt
      901 gcttgccaaa atttccacct cgatcaactt gttctatggc ttacataaaa attctagcac
      961 attttcagaa aaaatacact ttttatttct tattttcttt ccgttctagt tcagataatg
     1021 cttcttctat ccaaataggt aactgctccg caatagtggt aaatccgatc ttacgatttt
     1081 tattcgtgaa ataccttttt ctgcgatatg gaacagctgg atttgttttt tctaacgttc
     1141 ttaaagataa actgattttt ttggaatatt catcaatgtc gatgatctga actgttactg
     1201 gctgtccgac ttttaacaat gaatggatat ttttcgtata accggattgt acttctgaaa
     1261 catgaataag tccttgcgtc tcgttatcaa gagaaacgaa tgcgccataa ggctgtatcc
     1321 ctgtcacttt tccttcaatt atttgtccaa ttttataagt catctacttc cctctcttcg
     1381 catttatcat tatactgtaa atagctcaaa aaaagaagcg acgaaaatga ctggaggtct
     1441 taagatgatc gaatttgata aacagatttc aagaaaagat acagaaagtg taaaatggga
     1501 cgcaattgct gagacatatc aaatggatga cttacttcct ttgtgggtag cagatatgga
     1561 cttcttgtct cccggtgggg tagctaaagc gtttagtgaa tacatcaaac atggaatctt
     1621 tggttatgcc actctgtctg ataaactata tcaggctatc attcattggg aacgccaaca
     1681 ccatgctgtg gagttgacga aagaaaatat cgtttttaca agtggtgtgt taaccagttt
     1741 agctgcagca gtacaaactt ttacaaaacc aggcgattct attttgattc atgacccagt
     1801 ttatcctcca ttttcctcta ttatagaaac aaatcaacgt cacatcgttc gaagctcttt
     1861 gctagaaaaa aataatcatt tcatcatgga cttgtctgac atggagaaaa aaatcgaaga
     1921 aaacaatgta aaagcaatga ttttatgcaa tcctcacaat cctggagggc gtgtttggag
     1981 caaagaagaa ttgaaacagt taagcgaatt gtgtttaaaa catcaagtga ttctgtttag
     2041 tgacgagatc catcaagatt taactttatt cgatcataca tttacttcca tgctaacgat
     2101 tgatcctaat ttagatgatc tactagttgc ttttacttcc gcaaccaaga ctttcaatct
     2161 agctgcaatc aaaaattcaa tggtatttat caaaaatcca gagatgaaag ctgattttga
     2221 aaaacattta gtgatgaacc aacagcacga aatcaacact tttggactga ttggaaccca
     2281 agcggcttat gagacgggtg gagaatggtt aagccaactg attccttatc tagaaaaaaa
     2341 tgttcaaaca gttaatcagt tttttgaaca gtatcttccg aaagtgagaa taatgaaccc
     2401 tgaaggaact tacttaatgt ggttagattt taccgcctat atttcagacg accaagaatt
     2461 ggagaacact cttgttcgga aaggaaaagt cgtattaaat cctggcatca cgtttggtcc
     2521 ttccggtcat gggcatatgc gcttgaatat tgcttgtcca gaagaaactt tactggaagg
     2581 acttaatcga atcaagtatg ctttagagac aatcgattaa atcatttatt caaaataaaa
     2641 ggacgagacc ttactaggtt tcgtcctttt tcataattac tccgtaccat accaaactat
     2701 tctgaaattt caattgtttc aatcactaca tcatgtacag gtcggtcttg tggaccacgt
     2761 tgtacatttg cgatttcatc tactgtgtcc atcccttcta gtacatgtcc aaagactgta
     2821 tgtcggaaat ctagccaagg agttccgcca cctttatacg cttcaatgat ttctgatggg
     2881 aatccagcac cttctagttg tccaagcata ttagctggca catttgtgtt atttacaata
     2941 aagaattggc ttccgtttgt gtttggacct gaatttgcca tagataaagc tccgcgaagg
     3001 ttgaacagtt cacgactgaa ttcatcttca aaactttcgc cataaatact ttcgccaccc
     3061 attcctgttc cagttggatc gccgccttgg atcatgaaat caggaataac gcggtgaaaa
     3121 atcacgccat cataataacc ttttttggaa agttcaatga aattttgaac cgtcttcggt
     3181 gctagttcag ggaataattg aacagtaatg tcaccacggt ttgttttgat aacagctttt
     3241 ggtccttttt cactttttaa atctagttgt gggaatgcca tattgtttcc tcctaatatt
     3301 tgcatacttc ataataataa taacataata cctaacctct cgtaaaaata ctagatttgt
     3361 tttcttttat ttttcatcac tagatacatt ctataactta ccgtttcgat ttcgaattca
     3421 aacatttttg agaagcattc tcaattaaat tctgatatag tgtgaaaagg gaggaatttt
     3481 tatggaaatc tatgacatta caatcatcgg tgcaggtcct gtagggatgt ttgccgcttt
     3541 ttacgcagga atgcgccaag ctaaaacaaa aatcattgac agtctacctc aacttggtgg
     3601 tcaattagca actttgtatc ccgaaaaata tatttacgat attcctgggt atccagcaat
     3661 aaaagcaagt gaattaatcg atcaattaga aaaacaatta actactttta accatacatt
     3721 ccatttaaaa gaagaagttc tctcgcttac tcgtgaagac gaagttatcg agattactac
     3781 aaataaaggc atccattatt ccaaagcagt cattttagct ttaggaaatg gttcattcca
     3841 gccaagaaaa ttgaatttag ataatgctga atcatttgaa aaccacggat tggattattt
     3901 cgtgaatgat ttgatgaagt atgctggaaa aaaagtcgct attgctggag gtggtgattc
     3961 tgctatcgat tggacgttga tgttagagcc tattgcaagc gaagtttact tgattcatcg
     4021 tcgcccggaa tttcgtgcgc acgaacatag tgtatcacgc ttgaaatctt catctgtcaa
     4081 cttgcttact ccctatctca tcgatggatt atcaggcaat aatggggaac tgacagatat
     4141 ccggttaaaa aaagtgaaaa gtgacgagac gattgatttg atgattgatt ctctgatcgt
     4201 caattatgga ttctcttcta atttagaaca tctttcttct tggggacttg atagtaccag
     4261 aaatgccatt actgtaaaat cagatatgtc tacttctatt ccaggcgttt atgcagctgg
     4321 tgacatctgt acctatgaag gaaaagtgaa actgattgct actgggctcg gtgaagcacc
     4381 tactgcagtg aacaacgctt tacactatat taatccaaag gaacgaactc agcctggtca
     4441 cagcacaagc ttatacgata aaaatcttcg tcctagttga ttttttatat ctctttgcat
     4501 ttcaagttaa acccgaaagc agtttcttgc atttttttca tgttccgtta acatgaaata
     4561 gagaaagaaa aaataaaggg ggagcaataa tatggtcgtc aaaactgaga ctttagaaga
     4621 aaaggcaaga gaactattga aggaacgtgg cgtaactgta gaagatatcg cacaacttgt
     4681 catgttttta caaaaagact atatttctga tttgactttg gcggattgta ctgaaagtgt
     4741 caacagcgtg ctaacaaagc gtgaagtaca taacgccatt atcactggaa tccaattaga
     4801 tatattagca gaaaagaaaa aattgatgag tccgttgcaa catattatcg aagatgacga
     4861 aggcctttac ggtatcgatg agatcctagc cttgtcaatc gtgaatgttt acggtacgat
     4921 cggctttacg aattatggtt atatcgacaa ggtgaaacct ggtattttaa aagaactaaa
     4981 cagccacgat ggcgttcatg tccatacctt cttagatgat atcgtcggag cgatcgccgc
     5041 tgctgctgcc agtcgattag cacacaaaga accagaaaaa agaagtcgcc ttactcaata
     5101 attcaacaaa aaaagaaaga aaacgtctat ttagacgagt tctttctttt ttgtttgttt
     5161 caagctattt tttcctaaga aaagaaaaac agcaaaaaat aattctaata atacaaaaaa
     5221 taagataaag ctatgcatga aaaattcttc tggaagtaca ttgatgattg gatcagtaac
     5281 gggatcgaat aaccagtcat cgttgttgaa aaacgtttca tgaaaaagga taaaaaagcg
     5341 atcaaatcct atcatcatga aaaaaccgaa aacaactggc agtaacatgc cgatttgaaa
     5401 cggacgaatc aaccgccaaa gccgatcatt cttttgcaaa tatttgataa acaaaatact
     5461 cgggatcaaa gtgatgaaaa acacagcata atccactaaa aacaaaattt tcacttcata
     5521 aaagtgatgg gctccgctag cagaaactgg gaaatctggc aagctgagga tggttttgaa
     5581 gggattattg agataattca ttaggtgatc aaaatttttc agtaacgtct cttgatctaa
     5641 agaagtataa tccaaaattt gcaaatgtcc gatatcaaat acgtatagtg gtcgaaagtt
     5701 gatcgtcaca ccaactgcca gactgatcag tgtcagaaat aggctgaaca atccagcata
     5761 ttccatccac tgccatctcg aatttttcat attagaagct ccattcatcc agtgattgtt
     5821 tcacataggt agctgggata ggcaacccag gtacatcttc ttcttttgta aaacctgata
     5881 aaacgagcaa agtatctata ttattgcgta tcccagcttg gatatctgtt tcatagttat
     5941 ctccaaccat gattacttct tctttttgca gccctaatac ttcaacggct ttatccataa
     6001 tgatggcttc tggttttccg atgtagatcg gcggcgtttg ggttgctgtc tctacaaaag
     6061 agatgactga ccctgctcca ggaagaaggc cgcgttcagt aggtatattc ttatctgggt
     6121 tcgttccaat gaaagtagca cctttttgaa tagcaagtgt tgctttaact actttttcat
     6181 aggtcagata attatctaag cctaccacta catagtcagg agcctcttct tcccatgtaa
     6241 atccggcagc taaaatcaag tcaatcaatc ctgcttctcc gataacatag acttttttcc
     6301 cttttccatc tgctttcata aaatcgattg ttgccaaagt agctgtgtag actgtctctg
     6361 gagctacatg aatgtcaaac tcatctgcta gacgattagc tactgtttct ggtgacttag
     6421 tcgtgttatt ggtaacaaac aagaaaggta attttctttt ttgcaattct tccacaaatc
     6481 gtttaccggc cggtatgggt tgtgtcccac gataaatcgt tccgtctaaa tcaattaaat
     6541 atcctttata gtccattcat ccactactct tccctttttc tgatcgtaaa tgctgttttt
     6601 gttttttcta cttgtttagg ttgttcttgt ttttttactt tttcagaggt ttttgctgac
     6661 tctgtttttc gatttttaat aaccggtttt ttgcgattag atgcgactgg tccttttttc
     6721 tcatcgatat acgcacgatt atggtttttt ttcttttttc ggcgctgagt tgtcttttct
     6781 tttttaccgc cgattctctc gatgacaaaa tacgcacaac caaaattgca atattcgtaa
     6841 agatagtctt ccaaggaatc gattcgctga tctggatgcg cccgtcgatt atccgcttgg
     6901 aaaaatcctt ttaggcgtag ttgttcataa ccccaatctc ctacgatata atcatatcgg
     6961 gctagtacat cactgtaacg ttctccaagc ttttctgcat taaatccttc acgataatcg
     7021 gacacaagcc gataatgtct ttcacctatc aaaaaattac tgtcatctaa cagtgtcact
     7081 agctcgcctt tgactttttc tgctttaggc tcctcaacga tttcttccaa agcagctgtc
     7141 agttcttcgg tgactgttgt ttcctgttca gctgatgatt ttttcttagc aatttctgtt
     7201 ttatgctcaa cgttctgctg ttcattttgt tttgcagaca tgcgttcacc acctatcttt
     7261 tttattatac cttgttttta tttgattggg tagtgagctt tcaagtaatc tcctaccaca
     7321 cttcggataa attcagggaa caaaaattca ttttttccag caatctcaat cgttggaaaa
     7381 aatggaacaa acatcaaatg atctacggta gtaaaagtat aatttttatt cagatcgatt
     7441 ggcttgttct tccaaaagac ttgatggtta atagaatcat atgtgattcc attatagacc
     7501 atctgcccaa aaatcttacc gcgaaatccc attcccttca taggatagtt acgtaaaaag
     7561 ttacgatttt tttctatttc taaaactaag cggatcagat catttccacc caatgtgaca
     7621 tttaacaagt gcatcggatg cggcaacgca gtgtgaagct gatcctgatt gacccgccct
     7681 tttggaattt cagttaaaaa cagaccactg tttaatattg ctgcttccgt ctttcctcgt
     7741 tctttcaccg cctcaaaggc tacttggata aacgaatgct cattgaagat atctagactc
     7801 agagaaaatg gcaaatctgc tacttctttt tcttttaata attcatgccc acgttctaga
     7861 caactattta tttcttgttc atcttctgta aaagctgtca ttgtttcggt agggatggct
     7921 ttggctgaat gcttaaggat ttttttctct tcatcgatgg ttaaatggac ttcaccgaca
     7981 tactgcccgt actttccagc ggctgctatt tggacatcat tgattacgtg accttctctg
     8041 aataaatgat gggtgtgcga tcctaaaata acatcaattg ctggtatttc ttttgcaatt
     8101 tggaaatcat cctgaatccc gagatgactc atcaaaacta aaacatccac ttgtgaacgt
     8161 aaatcttcga ctaattctgg caaaatatca taaggattcc gtatgtccca gccattcgga
     8221 ttataagtaa gcggaaatgg agcagtaaat gcaattagtc cgattttcgt ctggtgtttc
     8281 gttgtaatga ttttatatgg tttcgtccat gccggtggct ggagcgtatt tttatcgaat
     8341 aagttatcca ggatgatatc aaactcagca tgatcgtata aatgattcaa ctcttctttg
     8401 gaatttccta cgccttcatt gtttcctatc gtcgctgcat cataaccaac ttcattcatc
     8461 agcaagatat tttcctgtcc attcgttgct tctgacaatg gatgccaacg atccacaaaa
     8521 tcacctagat ctactgcaat cgttgtcgtt ttttctttct tttcgttttc tcgtttacgt
     8581 tgatccaaaa accttctgat ccttggccaa ttttctaaat gagaatgcag atcattcgta
     8641 tgtaaaatca ctattttttc catgtaccct ctcgcctctc tttatcttta tcataccata
     8701 ggcagctttt tcttccattg aaacaagctc tatttcagag tttttcctgc cttgaagcaa
     8761 attgtataag tacaatattc gataaatcag tctggctaaa aaatcaggaa cattcatttt
     8821 tacagtacta taaaaataaa aaaaacagac ccgaaagtct gttgtcgttt cattataatc
     8881 agacacatgg cggaacctgc ttagtgctgc ttccttccag acctgacacg cttcacaagc
     8941 ccaccattgt cctagccttt cggcaaagaa tagtatacct tatttttcat tcgttgacca
     9001 gtcttttttt aatttctttt ttcgctggcg gagctttcgg aaaaagtcag tcaaaatcat
     9061 cccacattcg tcttctaaaa tgccaccttc tacatatgct tggtggttaa accgctcgtc
     9121 ctccaaaaga ttcatcaagg taccggctgt tccgcctttt ggatcatacg cgccgaaata
     9181 aacttctgct acacgagaca aaatcatcgc gccgctgcac ataggacaag gctctaaggt
     9241 aacaaaaagt gcagcatctt ccaagcgcca gcttcccact ttttcacagg cttccttgat
     9301 tgcaagcatt tctgcatgtg tagtagcatc ttgcgtggtt tctctaaggt tatatcctct
     9361 tccaatcact tttccatcca atacaaccac tgctccaatc ggaacttcat gaagcatttc
     9421 tgctttcttt gcttctgcca atgcaaggcg catccatttt tctttttcta ctgcatcaag
     9481 atttgtattt accaattacc cttccctgcc tttgtttttt cttgttttac tttagcatat
     9541 gataaaaagg ctgtaactaa ctttttttct atggtaaaat aaatacaaga ggtgaacaag
     9601 atgaaaatgg ataaattact tgctctttac ccacaagcac agaaaaaaaa ctctccagca
     9661 tcagaagcgg atatcctttc ttttgcaatt gatgatgctt ttatctggat caaacaagat
     9721 tcattatctc aacaagaaac cagccttttg aaagcgttat tccctgtaat caacgatcaa
     9781 aaaaaacacc catggtatca ctatcttttt aaagatgctt cttgtgttca agaaaaaagc
     9841 tttcgtttga tccagcttca cgtcgaatca aaaggagaat tcttaaaaaa agaatggcaa
     9901 gatactattt tggaattatt tcgctattct gctgatttct ttttttatac agacacagat
     9961 gcgctcttag tcgaacaaat aaaccgtgat tatcttgatg ctactgaaat caacggtatt
    10021 tttctatctt tagatgctga ttttgatacg acaacgtctg tattcgttgg ttctttccat
    10081 tcacctggca ccgacctcgt ccctttgttt gctgaagaaa gaaaaatttt tttaacagag
    10141 caaaacaatc tttatactca cagccgtact ttttctatgc aagatgtggc tttacattac
    10201 tatacaaaag atactgtaaa agatagtaag ttgatcaaaa gttacataga actgatcaaa
    10261 caaaatgaaa tggaagtgat cattcaagaa ttatggaatg aattaggcaa tgtcagctct
    10321 gctgcaaaaa cactgtttct tcatcgtaat actctaaaat atcgaatcga aaaatttcaa
    10381 gaacagtctg gtttcaatct aaaaaaagcc aacgatttac tgttttgcta tcttttattg
    10441 cttcatgaac ataattaaag atagattaaa ggggttgtga caataatttt gtcacaaccc
    10501 cttatttcga atgaatagtg ttcaaaagct agtttctctt acatcatttt ttcaacaaaa
    10561 tgcattagcc ggtcttttac atcttcggtt gaatctttga ttgaatcacc ataaacagag
    10621 attttctttt ttcctgattt gatttttgct aacattccca tcaaagaatc caagtcacta
    10681 tctgaaagac catctacgat ttctagtaat ttttcatttc catcaaattt gtcatagacg
    10741 aattttttta ctttcgtccg agtagtcata tgatggatct tttccattac ttttcccgat
    10801 acaacgactg ctgtcgctac actggcagcg gctgctacgc ttaatccgat tgttactttt
    10861 gttgatgttt tcataagtat cagctccttt ttatctatct ccatcatagc atagacaaaa
    10921 aaataaacga actaatccac tcagtgaaat ctcaatcctt tagggaaaaa gttctttact
    10981 gttcctttta cttgtttccc aaatccgaca ggtatcttat ctaatactag caaaacccat
    11041 ccttgattcc catcacgttg aaatgtttct cctgctgtgt aagattgcca ttccttttga
    11101 gtgatcggca agcaaggtat attctctatc ttttttgtag caagcgctaa tgcatagcta
    11161 ggttcaaatc gattcttttt gaaatctcct aaatgcaaac ctgtacgtac gacttttaaa
    11221 ccatcgagag aaggggctaa ctcaggaact tcccaaagat ggtcgttgaa cactaaaagt
    11281 cttccagtag cttcataatg aaaatcattt gaaaactccg tccagagttt ttcctgctct
    11341 tttgtcattt gcactttact tttttttcgt gtcttctttt ctttatgcat ctgattttgt
    11401 ccatgaaaag tcagctttgc aacaaaatgt ccttcaccct gatctttatg aggccatata
    11461 cgtattgttt tttccaaacc agctacgctt ccccattcag aacgtcctga actaacggat
    11521 tgagtcaaag gaatctcctc aatcgttact ggataatttt ctacaagcca gctaatgatc
    11581 tcttcatttt cttctggtgc aaacgtacaa gtcgaataaa tcagttgtcc tttatttttt
    11641 agcattttta ttgctgaaga caaaatctct tgctgacgtt tttgacagta tagcggagat
    11701 tcttctgtcc actcttttat tgcatttgga tcttttcgga acattccttc tcctgaacaa
    11761 ggagcatcaa ccacgatccg atcaaaaaag cccgaaaaat gagggacaag ttctgcgggt
    11821 gcatgatttg tcactattgc gttcgaaact ccccatcgtt ctatattttc tgataaaatc
    11881 ttcgcacgtt tcggaaagat ctcattcgtc actaataacc ctttcccctt catttgagca
    11941 gctaattggg ttgatttacc accgggagcc gcacacaaat ccaaaacttt ttcaccgggt
    12001 tttgctgcag cagctgttcc aacgatcatt gcacttggtt cttggctata ttcataccca
    12061 gcttgatgga ggaaagactt tccattgaca gtgccaagaa atccctcatt gctgtaggga
    12121 gcgggttgta attcttcgct atggtaagtt tggaccatgt ccaatcctgc cggttttagt
    12181 ggattccacc gaaatccttt tttcacgctt ccttgttcaa gcgcagaaaa aaaatcggat
    12241 gcttcttcgc ctaaaagaag acgatatttt ttgataaatt gctgtggtaa cgttgtcgct
    12301 tcctccttca ttccaatgtt tcgttagaca ttttacaatc ttttttacga aaaataaagg
    12361 tggctgatct actttttcat gttgctgcct aaggtgactg ttcctttaag atattttcca
    12421 agtattcatc cgtcacctcg tttttatccc aaacagcgtt catcatttca agaaaatctt
    12481 gagaagaatc atctgagcgc aaacttccca atgcattaag ccataccaat tcaagcgact
    12541 tttcttcttt gatcttcgtg tgacctttga catatgagaa aaatggccgc ttaaatagcg
    12601 aatccatgtc taaatcagat tttgcaatga tttcacgaat actttcatgg atagaaaaaa
    12661 aatctttcaa taagtagaca atgcttaaaa catcatcgga actgcattca gctaagtagt
    12721 tttcaaaata aacagtgatt tcttctaata tcttctcttt taacccgctg attgatttga
    12781 aatgtgtata aatcgggtat gtagaacaac cgcagaactc tgctaactct cttgcagtaa
    12841 ttgacttcat tccatattct tccacgtata ccatactttt gaacagcaaa tattctttac
    12901 tataatttgt tactctcccc atcattctta cctccgtctc ttttcatcta cccataaata
    12961 aataacataa ataattctaa aaatattatt gataattatc aaaacatatt tagttatatc
    13021 cattaaaaat caatttttcc gccttaaaaa caagaatatc ttgacaaaat accctaggaa
    13081 ataaacaata gaataaacaa ggtaacaaaa aaattaaata acgttatata aaaaagaagg
    13141 cgacactctg tgagaataac acagactgaa atgactttcc actcacagtt tttgtctaac
    13201 tatatacaaa aacagaataa aaaggaggta tttatgctaa ttgaagcaag aaaaaaagag
    13261 ttacttgttc tacaaatggt cattcaaaaa aataattgtt ctttacaaga attatccaat
    13321 gacttacata ttccaaaacg gacaatcaaa gaactgatcc gaaaaataaa tgtatcactc
    13381 aagcaatttt tattgattga tgaatttatt tattctaatc ataaaggaga gatccaaacc
    13441 aaagaaaccg atcaaactaa aaagttagct gttttttcta agttaaaatt atgctaccta
    13501 aaagaatcca atcgttttaa ctatttgatg ttactaatca attatccaca aactgctgta
    13561 ccaaaaaaat atttacttga acaactttat atatcgccct cctatctcga aaaactgaca
    13621 aaacagctca atcattcctt aataaaattc catttacgga tcctatctgt aaaaaattgc
    13681 tgtactcttg aaggaaatga gttatctatc cgtctctatc tttacttttt tctttcagat
    13741 acatttggag gtaacgattg gccattttcc tcacttgaat taaatgcact aaaaatgaac
    13801 agtacagatg agcaaataga aaaaatttca aaacaagaaa aaaatatcta cttgctgtta
    13861 actttattca tattacgaaa caaacaacag gcatattttc caaaaacttc ttctgaaatc
    13921 actgaattga tggacttatt gcagcataca catgattatt cagaatactt tacttctttt
    13981 tcagtgagtc gcccttgtga agagacagaa acagagagag cctactttaa ttattttttc
    14041 tattgttttt ttccaaatca aatctctttt cgacaaaaac aggagattgg ttttttattt
    14101 tccacaagca aaaaccttat ttgtcgacaa gtcggtcaat tgatgactta cttaactcaa
    14161 cagtttcctc tcaaccattt agaaaataaa ataccaattt atttttattt tcttgtgttg
    14221 gcagttgttt ttttcgaact gttgggtgaa tccagcagta gtttttctac actttgcttt
    14281 ccagaagcca cgtccaatca ttctagttct tttatacagg aaaagaaatt aagagaaaaa
    14341 atcgatacaa ttttttcaaa aaatggggaa agaaaccaaa tcagtcaata ccttagtcaa
    14401 ttgatccaac acttactaca aacagaaacg aaagagcagt tactcatcca tttgcagata
    14461 accaaacagt ttacaggaaa ttatcatctt caaagccatt tgcagcagtt atttcgcaaa
    14521 gatgctgtta aaattaccgc atattcagaa catgctgatt tgatcattac agatcagcat
    14581 gagaaaattt cagatgaaac ggagactttc tatctggata caacgcacaa tacagtgtta
    14641 tttggcaagt taataaaagc ggttcatgaa ctgtatatga aaaaaggtta tgagaacaaa
    14701 acaaagagga tgtgacaaaa ttcttgtcac atcctcttat tccaaataaa tggtattcaa
    14761 tcagctaact ctcggtatta gctcagatca aagcgctgat ttcacaactt ctttatttta
    14821 atctcttcgg ttgccgccga acaataagat caagcgcaac agctgcagga atgtcgaaag
    14881 cgctgctgca acataagtca gtgctgctgc aaataatacg tgtcttgcca tcggtacttc
    14941 ttcttccgtc agtagtccgc cttcactcaa aatttggatt gctcgccgag acgcgttaaa
    15001 ttcgactggt aatgtcacca attggaaaag taatgctaaa gaaaaagcga aaatcccgat
    15061 attgattaac gtagagttcc agctaagcaa tacacctacc ataatcaagg ggaacgaaat
    15121 catcgaacca aagttagctg ctggaacaag tgctgcacga atcttcaatg ggacataacc
    15181 cgaagcatct tgtaccgcat gtccgcattc atgagctgct acacctatcg cagcaactga
    15241 agtagactgt gcagttgctt gagacaaact caacatctta ttacctgaat tgtagttatc
    15301 tgtgagatct ccggcaattt gttgaacacc gacattattt atctgttgac tttgtaatat
    15361 atattgtgct gcttgtgtac cagtcacatt gtttttgctt ctcacttgat cgtattttcg
    15421 gaaagtacta ttgacgtacg ctgacgcaat tccggaaata actaatccaa gaatgaccaa
    15481 aagaaatgtc ggatctaaaa aaccatacat tccataacca tacattttcg tttcactcct
    15541 tttcgtttac tttattttat cattagtagt aggaaaagaa tgtgaaaaga ccttgaatat
    15601 tctttaattc tttttcacaa attccgattt cagtttcatc ggtccaaatc cttctacctt
    15661 gcaatcgata ttatgatcgc cttctactaa acggatgttc ttgacttttg ttccttgttt
    15721 aatggcacct gacgcacctt ttactttcaa gtctttaatc actgtcacgc tatcgccctc
    15781 taacagacgg tttccatttg catctaatac cactaatccg tcttctatga cagtttcttg
    15841 ttcttctttg ttccattcgt tcccgcattc tgggcaaatc aacaagcctc gatcttcata
    15901 tgtgtactct gagccacatt ctgggcaatt tggtaatgtc atcttctttc tcctttaaaa
    15961 tctttagtga gcactattgt aacggaaaaa gaagatcttg aaaagataca tttgtgattt
    16021 ttactacaaa aggcacgttt tcgaacgaag tatcattctg tttttctgct cttatacgat
    16081 tggcatatat cttggatctc tttatagatt tcctctactt ctgctaaatc ttttgcattc
    16141 gcaccacttg ctaatggatg gcctcctcca tgatggcgtt tagccaattc attgatgatc
    16201 ggccccttag aacgtaaacg tacgcggtaa taccctgaag gctgctgaac aaaaatcccc
    16261 caagccagca cttcgtcaat cactccagga agtgaaacga tcgaagctgt ctctgaatca
    16321 tcgattccat atttatcaag aatttcttgc ggaaggatta ttcttcctgc accattttca
    16381 tccacctgga tattttgata aagataaccg gaaagtttag cgactttcat cggcatttgt
    16441 tcaatctctc tgttcaaagc acttgcatca aatggataat ttctcaatat cgaagcaatc
    16501 tctaatgtac gggacgtcgt ggagggatac aaaaagcgcc ctgtatctcc gacgattcct
    16561 gcataaagta accgtgcagc cttaacgttc atctttaaag attcaggaaa catcaaagca
    16621 aattctgcaa tcatctcact acagctactt gcttttgtat ttacccacac aagatctcca
    16681 taagggtcat cattgggatg atggtcgatt ttgatcagtt tttctgccaa ctgatatctt
    16741 tgatcactga ttctgggtga attagctgta tcagtcacga tgactagcgc tccttggtag
    16801 aagacatctt caacttcttg catttctgct aaaaagcgaa gcccttcaat cgtttcacct
    16861 acttgacgta tttctttttc tgggaaactt tcccgtaata gttcggctaa tcctacttgt
    16921 gatcctaatg catcaggatc agggcgcaaa tgcctgtgga taatgatttt atcgtatttt
    16981 tttattgtat ctactatttc ttgctgtact gtcatttcac tcctgctttc taagaacgtt
    17041 ccattacttg acaaacaacg attgctttgg aaacgatggt gttttcaata aacacttcga
    17101 tatccagttt agcggaacgt ctgccgattt ccaatacacg tggacgaatg tctaattcgc
    17161 tttccaattg gatcagccgc aaataatgta ggttcacttg ttcaatcaag atatttcgtt
    17221 tttggttcat caccattgtt ttttgtgcga catcagaaat gatttcgcta agtacgccaa
    17281 aagaaatggt tccaacgcca ttgaccattt gtggtgctac tacgaatttg aacttagggt
    17341 tttccaaacg atttccttca cggtcagtat caatcgtatg gatatttcca gatatctgat
    17401 ccgaaatcgt atctgcaatc tgcggttgtc gctggacaag ctgcatcgct ttcattacat
    17461 cttgccgggt aatcaagcct tccaatgtca agtcatcgga aacgaccggc atgacttcta
    17521 gcccatccca gatcatttga tggctaacag aggcaatact cattgttttc tttacactga
    17581 ttggttcttt cgtcatcacc cgatcgatga tctggtttgg cgatttccct aaaacatctt
    17641 ttgccgtaac aatccccatc aaacgatgat ggcggttgac gactggaaaa cgcgaatgct
    17701 gcgtttcttc tgacaaacgc tgataatcag aaatcgtatc tgtctgctgc aaataatgag
    17761 tcttttcagc tggcatatag atatcactga caagcatgat atcttttttg atcaattggt
    17821 cgcttaacgc tcggttgatc atggttgcga ctgtaaatgt atcataagag gtgcgtaaga
    17881 tcggcatttc aagatcatca gctagctttg caatctcagc agtcgtattg aatcctcctg
    17941 tgatcaatac tgcggcgcca tcttccaatg ctaatttttg gacttccgcc cggttgccga
    18001 cgatcattag tgatcctggc gtaatatagc gttccatggc atgtttagtc atcgcgccga
    18061 tgacgaattt attcaagacc ttgtctaatc ctgccgcccc gcctaaaacg tccccttcaa
    18121 tgatcctgac gacctcgcca aatgtcaaac gttcaatatg tttttttaat ttgcgttcga
    18181 tacggatggt ccctactcgt tgaattgttg aaactagtcc gacattttct gcatctttga
    18241 ttgcacggta cgctgttcct tcactgacat tcaattcttt tgcgatgctt cttacagaaa
    18301 ttcgattgcc aacaggtaaa ctttcaatat attctaaaat caaatcatgt tttgtcgcca
    18361 ttttctgcct acacttccag cgtttccgag acgctcatta tttttccttc actatcttcc
    18421 agtaactcta caaaagattc gggatcttgt tcaatgacag ggaaagtatt gtaatggatt
    18481 ggaactactt tcttggcacg aattgtttgc gcagcctttg ctgcatcttc tggccccatc
    18541 gtatagttat cgccaatcgg caagaaagcg acatcaatat cgaattcttc tgcaagcaat
    18601 cctagatcac tgaaataagc agtatcccct gcatgataaa tcgtttttcc ttctgcttga
    18661 ataataattc cgctaggctc gcccatatac tgaacgatac cgtctacttc atagcttgaa
    18721 ctatgctgtg catgtacgaa ttttaccacg ccgaatggaa acgcatgttt tccaccgata
    18781 ttcataccga atgaatctac tcctctgctg ttcgcataat cagcaatctc aacaatactg
    18841 ataattgtgg cttgattttc ttttgcaata ggaatcatat ctcctatgtg gtcactatga
    18901 ccatgagtaa tcagcaacca atctgtcttt acttcttctg cagttaagtc tgtcaatgga
    18961 tttcctgtaa taaacgggtc aatcatcacg cgttggccat tttccatttc aattgttaaa
    19021 caggaatgtc catgatacgt aattttcata ttttacacct cgcgttttct ctgtatcttt
    19081 tttattaaaa acgatttcat cacttgcaca tcaatgaaaa aatatagctg ctaaatatat
    19141 tttcattgga ttgatagtac agtatgtaca aagcaattgt aacagataat acaggatgca
    19201 ccaagtacca agcagatata atctcaagtt tgaggtctct gctctgctta gcttctcttc
    19261 tcgtccctta actaattaaa tcagcgtaaa taggatggac gatcttttct aaatcggcta
    19321 cttttatccg aaggcttctc ccgatttcac cgcttgacac aattacttct tctttttctt
    19381 ttaaagaact gtctgctaaa aaacaataat caggatgtgc gagttttatt ccaatagggg
    19441 tgtttgctcc gtggggatat cctgtatgca ttaatacaaa atccattcca ggaaaaccaa
    19501 ctttacgatc tttcgtcact tgtctcgttt ttttgtaatc taagtgatcg ttcaaaggaa
    19561 tcaatgcgat gatcacccca gttttgtttc ctttcactac gagagtttta catatcaaag
    19621 ctggatcaat ccctcttttt tgtagttctt ctgtgaaaga ttcttctacc acatgactaa
    19681 aatcaagtgg ttgatagctg atcttttgtt cttctaaata acgttcgact tttgtttgac
    19741 tcatcattga ttcactccct ttattctatc gtttattata aagcgaggga tgctgtattc
    19801 aaaaattatt tgtttttcgc aaaaaaagag caagacgagc actctataga gaggttcatc
    19861 ttactctttt tgtttatttt ttatttcgac gttgagtagc ttccataatg actggcaaga
    19921 tcactgggcg gcgttttgtt tgttcaaata agtaacggcc taattgatct cggatgtctt
    19981 gctttaattt gctccactca aaatcattgc tttctaaatg tttctcaacg attgtttcaa
    20041 tcatattgct gctttctttc atcagatcac ggctagcttt tacgtaaacg aatccccgtg
    20101 aagtaatttg aggttttgaa atgattttct tttctcgccg actgatagtg acaaccgcta
    20161 cgaaaatccc gtcttctgac aagatttttc gatcacgtaa aacaatgttt ccgatatcac
    20221 ctatgcctaa tccatcaatc attacatttt ctgcacttgt agttcctgca acactcatac
    20281 gcttgttctt atattccagc acgtctccgc gtccagtaat atagatattt ttgtatggca
    20341 tccctactgc atgagccaaa tctgcatgag cagctaattc acgatactct ccttgaactg
    20401 gcacaaaata tgttggtttc atcaaattga tcattaattg caagtcatta ggattggcat
    20461 ggccagaaac gcgcatattc tcagagatca acttcactgt tccaccagct cgataaatga
    20521 tatcttccgt tttcgccacg atggtttcca tcgcgatgct tggcgtagta gtgatataaa
    20581 ccaaatctcc ttcttcaatc ttgacattac ggtgtgtacc gtttgccatt ttttgcagag
    20641 acttgatggg ttcacccatt cggccagttt ctaaaatgat cagttcttct ggatcatagt
    20701 ttttcatgtc tttcaacgta acaagcagat cttcacttgg taattgaagt ttttctaaac
    20761 gcatcgctgt gcgaataatt cgttcgaaat cttgaccagt caagacaact tttcgttgtg
    20821 ctttttctgc tgcatccaat acttgttgca ctcgttgcaa attacttgct acacaagcga
    20881 cgatgatacg cccttcccaa tatttgatcg tatcaaatac ttcatctgct atttgggctt
    20941 cagaagctac aggctgagga ttttctgcat ttgccgattc acttagtaag gctaagactc
    21001 cttctttgcc gatttccgcc aatcgtgcat aatctgtttg atacattggg atagccgttt
    21061 ggtcaaattt aaaatctccc gtataaacga tactaccttc ttttgttttc agattgatcc
    21121 ccactgaatc tggtatcgta tgagtggtac ggaaaaagct cactactgtt tcaccaaagt
    21181 ctatttctgt atgctcatct accacatgga aatccttaaa tcctttggct gcttcattac
    21241 gactgacatt caattttgct aactcgatcg tcaactctgt cccgaatact ggtacagaaa
    21301 tttttgacaa caagtaagga agtgccccga tcgcatctgc atgtccatgt gttaaaaaga
    21361 caccagctac acgatcaatg ttttcttcta aatacgtaaa atcagggatt acgacgtcga
    21421 tccccaacaa ctcattttca ggatatttta gcccacaatc taaaataaaa atatcctcgc
    21481 ccacttctgc gacatacatg ttttttccat tttcacgaac gccgcctaat gggataattt
    21541 taatggtact cacaaacttc acctcttctt atgacatcca agtttaaaga tgtcgatttt
    21601 cttctttatc taaatatatg agccattcca atgaagcata tgcaaaatca ctatttctca
    21661 acttatggag aatcagcagg aaaattacca gcacatccgc gttctgacag ttggatgggc
    21721 attttatttt ggatatactt cattaacaaa atggatcttt tgcgaaacgc tatagccaga
    21781 atacttatat aagtattcag ctgttcccca ttattataca acaaataaac taaatcgcta
    21841 gtatcagcaa ttgttagaac aactatgcac gtaaaaatcc ctctgtagca tctaggattt
    21901 cttttgctat tcctctttca tttcttcttc gtcggtttga aacatacttt tttcatttta
    21961 ccacattttt tgcaataact atagtgactt tttatatata cagaacctca tgttgatggt
    22021 gtgcaaacag cataagattt aagctagctt taagataggt tgtctattat caaatgcatc
    22081 tactaggagg gatgcaaaat atgaatttta tgaaacgtgc atggaaaagt acaaaagtaa
    22141 aatggggacg ttcattgtta ttgtttgccg tgttcacagc cattcttatt tttgtgctag
    22201 ctggcctcac gattcgaagc gctgcagaag aagcagcgaa tcaagcacaa aaagaagttg
    22261 gagcaacagt gactttaagt gccaatcgag aagcttcatt taaaaaacag gaacaaactt
    22321 cttcaagcgg ttctaccact gaagaacgtc cagatccagg cagtttttct cttacaccag
    22381 tttccttaac ggacgcggaa aaaatagctg aattagataa tgtaaagagt tattcctttg
    22441 aaagttccgc ctcagctatg gcaaaagatg gaataactgc catcactagt tctgattcaa
    22501 gtgaagacag ttcagaaact actgatgcag gcggtgaacc tgctggagga atgggcggga
    22561 atccgcaaat gactcaagca gactttcaaa tcagtggtgt gtcagcaact gcacaaaata
    22621 gtaatttttc tgatggaaca gcaaaaatca cggatggtga aggaatagat gacagcgaca
    22681 aaggcacaaa caatgtagtc attgattcta ctctagcaga aacaaatgac ctggcagtcg
    22741 gagatacttt cacaatcacg agtactgaag atgaagatac cacttatgaa atgacgatca
    22801 aaggaattta tgaatccagc gaaacaagcg gcagtatggg tatgaaattc aacttcatga
    22861 atccgtcgaa tacactttac acttcttaca cttttgcaaa tgaactaaat gggacatctg
    22921 acgataacac gatagattct gctatttaca ctctatctga tccagataaa atggatgagt
    22981 ttctcaaaga agctgagaag ctgatcgaca cagatacatt tagcttacaa tcaaatgatt
    23041 ccatgtatca gtcaatgttg gaacctttaa acaacgtggc aagtttttct aaaaatgttg
    23101 ttttactagt ggctgtagcc ggtattatca tacttactct gatcattatg attaccattc
    23161 gggagcgtcg gcatgagtta ggcgtcttgc tatctttagg agaatccaga agtaaaatca
    23221 ttctccaatt gtttaccgaa gtggctattt gtatgattct tgcattagga gttgcttcgc
    23281 ttagcggaaa cgtcgtcgcg aatgccgtgg gacagcagct acttgaccaa cagacagaaa
    23341 ccacgacaca aaaccagcaa gctcctggcg gtggacaaat gccaggtaac agacaagaac
    23401 aaggcggtca acgcgatggt caacaaggaa ccacgaataa tccatttgct gtttctgatc
    23461 aagtcagcga attggaaatc aatgtcaaac ctgcacaatt gggactatta gccggagtag
    23521 catttggaat cagtctgttt tctgtctttt tagcttctat agggatatta agattaaacc
    23581 caagaaaaat cctattaaac taaaggagga atttgatgtt acggacagaa caattgggat
    23641 tttggtatca agatccgcaa gatgcgcttt ataaagatgt agaactgaat ttcgaagctg
    23701 gaaaaatgta cgctatttta ggagcaagtg gttctggaaa aacgactttt ctttcgctta
    23761 tttctggact agatgcacca aaagaaggaa aggtatacta tcaagatcgt tcactgaaca
    23821 aaatcgggtt aagaagttat cgtaaaaatg atgtctcgat tattttccaa gcttacaact
    23881 tgcttcctta tttatcggct ctagacaacg tcatagcagc aatggaaatc actaagacca
    23941 agcaagagaa ttatcgacaa gttgctttag atcgactggc tcgtgtagga attgatgaaa
    24001 tattagcaaa aaaacaggtg accaaacttt cgggaggtca gcagcagcga gtcgctatcg
    24061 ttcgtgctat ctgctgtgaa catcaactaa tcgtagcgga tgagcctact ggaaatctag
    24121 atgaaacaac ttcacaagat atcgtcaaac ttttccaaga aatcgcccat gaacaaaatc
    24181 gctgtattat catcgtgact catgagattg aagtagcaaa aagctgtgat gaagtctttg
    24241 aactaaaaaa taaaaaattt caaaaaatcg aagtttaaaa aacaggataa tga
//
LOCUS       DAFLWC010000039        24259 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.040, whole genome shotgun sequence.
ACCESSION   DAFLWC010000039 DAFLWC010000000
VERSION     DAFLWC010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24259
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.040"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(44..1339)
                     /gene="purB"
                     /locus_tag="L1V17_001462"
     CDS             complement(44..1339)
                     /gene="purB"
                     /locus_tag="L1V17_001462"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBN1236238.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1352..2476)
                     /gene="purK"
                     /locus_tag="L1V17_001463"
     CDS             complement(1352..2476)
                     /gene="purK"
                     /locus_tag="L1V17_001463"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HBN1236239.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2469..2957)
                     /gene="purE"
                     /locus_tag="L1V17_001464"
     CDS             complement(2469..2957)
                     /gene="purE"
                     /locus_tag="L1V17_001464"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBN1236240.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3373..4680)
                     /locus_tag="L1V17_001465"
     CDS             complement(3373..4680)
                     /locus_tag="L1V17_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBN1236241.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4683..5264)
                     /locus_tag="L1V17_001466"
     CDS             complement(4683..5264)
                     /locus_tag="L1V17_001466"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBN1236242.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5380..5477)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5836..7128)
                     /locus_tag="L1V17_001467"
     CDS             complement(5836..7128)
                     /locus_tag="L1V17_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1236243.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7125..7748)
                     /locus_tag="L1V17_001468"
     CDS             complement(7125..7748)
                     /locus_tag="L1V17_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236244.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7751..8587)
                     /locus_tag="L1V17_001469"
     CDS             complement(7751..8587)
                     /locus_tag="L1V17_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1236245.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8604..9491)
                     /locus_tag="L1V17_001470"
     CDS             complement(8604..9491)
                     /locus_tag="L1V17_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1236246.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9507..10790)
                     /locus_tag="L1V17_001471"
     CDS             complement(9507..10790)
                     /locus_tag="L1V17_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1236247.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(11473..12156)
                     /locus_tag="L1V17_001472"
     CDS             complement(11473..12156)
                     /locus_tag="L1V17_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBN1236248.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12174..12791)
                     /locus_tag="L1V17_001473"
     CDS             complement(12174..12791)
                     /locus_tag="L1V17_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBN1236249.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(12801..13625)
                     /locus_tag="L1V17_001474"
     CDS             complement(12801..13625)
                     /locus_tag="L1V17_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBN1236250.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(13618..14178)
                     /locus_tag="L1V17_001475"
     CDS             complement(13618..14178)
                     /locus_tag="L1V17_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236251.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14352..15308
                     /locus_tag="L1V17_001476"
     CDS             14352..15308
                     /locus_tag="L1V17_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1236252.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(15613..16569)
                     /locus_tag="L1V17_001477"
     CDS             complement(15613..16569)
                     /locus_tag="L1V17_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HBN1236253.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            16673..17275
                     /locus_tag="L1V17_001478"
     CDS             16673..17275
                     /locus_tag="L1V17_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBN1236254.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17363..18862)
                     /locus_tag="L1V17_001479"
     CDS             complement(17363..18862)
                     /locus_tag="L1V17_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HBN1236255.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(18878..19402)
                     /locus_tag="L1V17_001480"
     CDS             complement(18878..19402)
                     /locus_tag="L1V17_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBN1236256.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            19700..20449
                     /locus_tag="L1V17_001481"
     CDS             19700..20449
                     /locus_tag="L1V17_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBN1236257.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            20440..21225
                     /locus_tag="L1V17_001482"
     CDS             20440..21225
                     /locus_tag="L1V17_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HBN1236258.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21194..21910
                     /locus_tag="L1V17_001483"
     CDS             21194..21910
                     /locus_tag="L1V17_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBN1236259.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22012..23046)
                     /locus_tag="L1V17_001484"
     CDS             complement(22012..23046)
                     /locus_tag="L1V17_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HBN1236260.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(23050..24108)
                     /locus_tag="L1V17_001485"
     CDS             complement(23050..24108)
                     /locus_tag="L1V17_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBN1236261.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
BASE COUNT         7188 a         5222 c         4225 g         7624 t
ORIGIN      
        1 ttttgctatt ctattttaat tgaattttgc aactcactct tctttattcc aaacctactc
       61 gtttgaatat cacgtcaacg tttttcaaat gatgatgata atcaaaggca tcgtctattt
      121 cttctttaga taataccgat gtgatggttg gatcttcttc taacagcggg cggaactgca
      181 cttggttgtc ccaagcgtac gcagtttttg gctgaacaag atcataagct tcttctcttg
      241 tcattccctt atcgatcaat ttcagcataa cgcgctggct ataaatcaaa ccaaatgttg
      301 cagacatatt ccgcttcatg ttttcaggaa agaccgttag atttttaacg atattgccaa
      361 aacgatttaa catgtaattc aataaaatcg tggtatcagg caagatgatt cgttctgctg
      421 aagaatgaga aatatctctt tcatgccata atgtgacatt ttcataggca gtgaccatgt
      481 gtccgcgcac cactctggct agaccagcca tattttctga accgatcgga ttccttttgt
      541 gcggcatagc agaagaacct ttttgacctt tcgcaaaaaa ttcttctact tcacgtgttt
      601 cggatttttg caatccgcgt atctctgttg caaaacgttc aatacttgta gcaataagcg
      661 ccatcgctga gaaatattca gcatgtagat cccgagggag aacttgagta gagatttctt
      721 gtggacggat ccccaattgt ttacatacat actcttcaat aaatggcggg atatttgcga
      781 acgttcccac tgctcctgag atttttcctg cttctactcc ttttgccgca tgttcaaatc
      841 gttcgatgtt ccgtttcatt tctgaatacc atgtggcaag tttcaatcca aaagtagttg
      901 gttcagcatg gacaccgtgt gtccgaccca tcatcactgt atatttgtgt tcttttgctt
      961 tttcgccaat gatttccgta aaacgtttca agtcttcccg taaaatatca tttgcttgct
     1021 tgatgagata gccataagca gtatctacga catccgtact tgttagacca taatggaccc
     1081 attttctttc ttctcccaat gtttcagaaa ccgctcgtgt aaacgcaacg acatcatggc
     1141 gtgttaattt ttcgatttcc aagatccgat cgatatcaaa tgatgcatgc tcacgaattt
     1201 ttttcacatc ttcttgcggg atttcaccaa gttctgccca agcttcatct gctaaaatct
     1261 cgacttcgag ccacgcacgg tatttgttct cttccgtcca gatattcccc atttcagggc
     1321 gtgtataacg ttctaacatg ttttttctcc tctaatccca aatattcgtt tgtttgattt
     1381 cttccagcgt ttgctggatg tcttctgtca agatagtgat atgtcccatc ttgcgacctt
     1441 tttttgcttg tttttttcca tagaaatgga attgccagtc tggcttattc tcaatcaagc
     1501 gatagctttc cagcagttgt tctcccaaaa cattgaccat tactgcattg cttatcaaac
     1561 gtactttttc tcctaatggc caaccacaaa tacctcgaat atgggcatcg aactgactca
     1621 tagaacaagc ttcaatagaa taatgtccag aattgtgagg acgaggagct aattcattca
     1681 catatagccc gcctgttttt gttaaaaaca tttctacccc taaaacacct gaaaggctca
     1741 ctgcttctgc aatcacacgg gcaatacgct cagcctcctc gatcacatcc tgatcaatcg
     1801 cggctggagc aatcgtttca tgaagaatat tgttgtggtg gatgttttcc acgaccggaa
     1861 aagtcgtgaa atctccttga ccatttcctg ccaccatgat cgaaatctct ttttcaaacg
     1921 ggatccatgc ttctaaaaca caggttcctt ctcttaaaag gtccatggca ggagctagat
     1981 ccgcccgact tttcaaaaca tactgcccct tgccatcata gccgcctcga gtggttttca
     2041 aaacacaagg atagccgatc ccgtcaatcg catcttggat atccgtcgga ctgacgatcg
     2101 ttgcataagg agcaatcacg atgttattcg tttccaaaaa agatttttct aacaggcggt
     2161 cttgcgtaat cgcaagcaag tctgtccctt gaggaataaa tgacatgggt aaaatcgcat
     2221 ttaacgcctc tacactgacg ttttcgaatt cataggtaat gacatctgtt cttctggcaa
     2281 gctctttcag cgcaaaggtg tcatcataga cactttcaat gtgccaatct gcaacttgtg
     2341 cggctggaca atcgctcaca ggatccagca cacctacttt aaagcccatt tcttttgcac
     2401 taatcgccat catacgacct aattgaccgc caccgacgat cccgatcgtt gaaccaggca
     2461 acaaaggttt aaccaagttg atcactactt tctataacag ttttagccaa cattgaacgt
     2521 ctttcagcca atttagcctc caattctaaa tcatacatgg aaagcatctg tatcgcaagt
     2581 agtccagcat taattgctcc cgcttttccg attgctgtag tagctacagg tactcctcca
     2641 ggcatttgga caatcgaaag aagcgaatcc aaaccattta atgttcgtga ttggaccggt
     2701 acaccgataa ccggcaaagt tgtttttgat gcgaccatac ccggcagatg cgcggctccc
     2761 cctgctcctg caataatgat tttgattcct ttttttcgag cgttttgtgc atattcaaac
     2821 atcaaatctg gggttcgatg agcagaaacg accttttttt cataagacac accgaattca
     2881 tccaatattt gacatgcttc tttcattgtt tcccaatctg aagtactccc cataatcaca
     2941 gagatttttg ctgtcattgt ttttcctccc agtttttcta cattcatatt ttaacaatca
     3001 ctttttttga tgtcaaagaa atttcgaatg ttaacaaaga aaaacatttt attgttcgtg
     3061 tttattaaag ataaaaaaaa ggaatgtgac aaaagttagg tcacattcct ttttatggat
     3121 aaacggtgtt ctcctgccaa ctcctcggtc acaaggaaca atattcaaca aacatgagaa
     3181 gctttttttt gaaattgttc cttgtgactc ggagatgaac ggcaggctca cgacctcttc
     3241 cttcaacggt gttcaatcag ctgaccctcg gtattagctc aaacaaacgg caaaatacga
     3301 ggaactattt ttccgtttgt ttctctaaca atcaggtcaa aacgctgatt tcacaacctt
     3361 tcttttgctc tattacttct tgaaggcttc ttccaatatt tcttcatctt ttttcaatcc
     3421 attaaagatc aaattcaata tgatagccgt aatgctactc attacgatgc catttccagt
     3481 gaacatttgc aatgtttgcg gcatttgact gaataatgtc ggcgtaacat tgaaacccag
     3541 cccaaatcca acagaaacag caacaatcaa tagattttta tcattgctga aatcaacttc
     3601 caacagcata cggattcctt ggactgccac catcccgaac atgactaaca ttcctccacc
     3661 aagtaccggc tcagggatga tttgtgctaa cgcaccgatt ttagggaata atcctaaaac
     3721 aatcaagaag aatgcagaga aatagatggg ttttcttgtt ttgattcccg aaagttgaac
     3781 caatccgaca ttttgagaaa agccagtata agggaatgta ttgaaaatac cgcctaagat
     3841 aacggcaagt ccttctgcac gatatccctt tttcaattct tcttctccaa catttttccc
     3901 agtaatgtca ccaagtgcaa aatatacacc tgttgattct accatgctga ccatggaaat
     3961 gatgatcatt agtaaaatcg accatacgtc gaaagttggt ttaccaaaat aaaagggttg
     4021 tggaacatgg aacaacggcg catctccaat cgcgctcaga tcaatcattc ccatgaaagc
     4081 agctaagatg cttcctccga ctaaaccaat caataccgcg attgaacgaa tgaacccttt
     4141 tgccagcatt tgcacgccta caattaggag aatcgtcaca aatgcaagta gcagatttgt
     4201 tttgtcacca aaatcagctg ctgttgcatt acctccaccc attttctcga ttgctacagg
     4261 aatcaaagtc aaaccaataa cggtgataac cgttcctgtt actataggag ggaatagttt
     4321 tttaatttta gaaaagacac cagaaactaa cacaacaaag atcccagaag cgataataga
     4381 tccgtagata gctcctactc cttcattggt tccgatcaag atcagtggag ctactgcttg
     4441 gatcgcacat cctaaaacga caggcaagcc aattccgaaa aatcggttaa ctgtcaattg
     4501 caataatgtc gctaatccac acataaagat atcaattgaa atcaaataag tcatctgttc
     4561 ttgattaaag cctagtcctg taccgatcaa aagaggcacc gctactgctc ctgcatacat
     4621 cgctagcaga tgctgcagcc ctaaaaccgc agcttttcca ttttgtgttt ctttttccac
     4681 gattatgcgt cctcctcaag aaactcaact tgtccattcg tcaaggaagc aatacgcgca
     4741 agagaaacga ctctcaatcc catttcttca agtaactgac gtccatcttg gaaagacttt
     4801 tcgatgacga tcccgattcc ttctacttgc gctccagctt gctggcataa ttcgatcaat
     4861 ccttttgccg cttgtccgtt tgccaagaaa tcgtcgataa tcaatacttt gtcttctgaa
     4921 gataaaaatt tacgagaaat agaaatcgta cttgtcactt gtttcgtaaa agaataaaca
     4981 gaagctgtca ataattcttc atccatcgtc aaactttttg cttttctagc gaagatcatt
     5041 ggaacatcta attctcttgc agcaaataaa gctggtgcga tcccagaagc ttcaatggtc
     5101 acaactttcg tgattccttg ttctttaaat acttctgcaa accgttttcc catttgttcc
     5161 atcaatacag ggtctacttg gtgagtgacg aagctgtcga cttttaatac gccctcgcct
     5221 aatatacgtc cgtctttttg aatacgttca actaattctt tcactttatt tgctccttta
     5281 tcatttatta ataccgaaat aaccgctttt gtgcaaaaac ctactatgtt tctgttaaag
     5341 aaaaacaccc tccactttat cataagaaaa gaagggtgaa atagccaatc ttttacttat
     5401 agtccagcat ttacggtact ggctagaaac tgtcatccat attatgacga tatataagta
     5461 ggtatgtaaa actaataata gtgtaaattc attttcttgc aactgttttg cacgtgaagg
     5521 cagtttgcca tatttgaata aaaaatgttg tttcaaatat tgaaaacagt ctaacactac
     5581 tttctgaaac tgacaacgtg gtttacttat ttttttgtaa aatctaatga tttttaatgc
     5641 attattcctt tttgttcggg tttaaatagt tatttttatt ttctcctatc taaaaaagca
     5701 gcccacataa aaagaaggca tgacaaaaag catgtcatag cccctttttc cgaataaata
     5761 gtgttcaaaa gacagcctat cggcaataag gcaagatttt ataaactacg ggaagtaatt
     5821 tccgtaaatc tattcttatt cttttaagct gacaagctcg tcaatcacta ctgcttttcc
     5881 tgaagcaata gaatgatttg ctgcgattcc tgtcaaaatc gacaaaatac catctacgtg
     5941 agttgctgcc cgattccacg gatcttcttc tttttcttca ccaaatagat catctaataa
     6001 acgcggatct cctccgccat gtccgcccgc ttcttgttcg acgattacct catatggctc
     6061 accgaacatc ggatagacat ggatggactg aagaacggct gctccttcat cctttttatc
     6121 tccacctgca ttgatgtaag acttttcgat cactttcatt tcgatccgtc ctttgctgcc
     6181 attgaaagaa acattgaatc cttcccacgg catatacgcg tttagcgaat acgtcaaaat
     6241 cgcaccagtt tcatatttga ccgttacgcc tagtgtatct tcaatagaga tatcatcgga
     6301 aaatacactg cggtcacgaa tatatccact gtctttttct gcttctaaat acatttctcg
     6361 caattcctca ttggctgaca ggtctatagc aaatggatca gctttagcta gttcgcttcc
     6421 atagcatcga ctgtaaaata tttctactcc gcgtttctcc gcattatgca tcccataaaa
     6481 gtttaatcca ccgaatgcaa ataccttttg gggacggctg ttcaaccaaa aattcactag
     6541 atcaaaatga tgggtagatt tatgaacaag aagcccgccg ctattgtgct tatttcgatg
     6601 ccatcttctg aaataatctg ccccgtgttg cgtatttaac agccattcga agtggataga
     6661 aaacacatca ccaatcacat cactttctat cagttccttt atcttcgtgt gatacggtgc
     6721 ataacgataa ttaaaagtga ctcgcaggct tcttcccgtc tgtttttgga ccgttattat
     6781 ttcttgagct ttttcctcat cgatagtcag aggtttttcg caaataacat catatccttt
     6841 tttcattgca cgaatgatat aatcatgatg cgttcgatct actgacgtaa taatgacttc
     6901 agccggccgt acgtcatcca gtagttgctc aaattgtgat ggcatacatg tctttacttt
     6961 tttctgtcca tacttgttca caagtatccg atttgcataa tccatccttg tttgagatac
     7021 atcacaaaaa ccgactagtt cacaagtttg atgatacgta gaggcaattg cctcataaaa
     7081 aaaacgcgct ctcccaccaa gtccgacttg tacatatttt ttcttcattt aaagtcattc
     7141 tccttttctt ttaagcaaaa tactgtgaca aatggcagcc ctggatacag taatgcagtg
     7201 agtaaaaaat catgctgtat acaccagaac agtccataca aaaggcataa ataccacaga
     7261 aaccccttga cgttttttga caacagccag atattccttt tgatcaaata aacaagacta
     7321 tctgctttat cttctttgca gatatcaatt agcgtactaa aaaaactatg ggatacaaaa
     7381 agcaacagac acaatagaaa aggaatcaga taccaagctc caatctttcc cactaataaa
     7441 taccaatcaa ctgcaaaaat aatgacaaac agctgaaaca acgtaatgat gaaacacatc
     7501 cgtttgattt ttcctttcct ccaacatacc tttttttctg ccaagtaatg gacagataga
     7561 taataagaag gatacatcat caaaaaataa atcagataga caacacgagc agacagcact
     7621 aatcctaaag tgaacaaaca tcctagaact aaagcgaaaa gagcattact gataagactg
     7681 gttaaaaaaa tccgacagac atagtagttg agcttgtaaa gaaacatctc ttctattggc
     7741 tttttcatat tcagcccttc agaccgcttg tactgatccc ctggacaaga tatttattga
     7801 agaataagaa aatcagaaaa accggtagca gcgacaacgt agacatcgca aacatactcg
     7861 cgtaagtcgt actagatcca gcgtctgcaa ataatttgat ggcaatcgat accgtgtaag
     7921 atctcggctt gtttaaataa atcaatggtc ccatgaagtc gtcccatttc caataaaact
     7981 ggatgatgat cgtcgtgatg atcgaaggtt tcagcaaagg aaaaataatt ttggtaaaga
     8041 cactatactt gctgcatccg tcaataatcg ctgattcatc taactctttg gggatgctga
     8101 ccatgaattg catgatctgg taaatgaaaa atgcttgtcc aaaaaaatgt ggtaaaatca
     8161 gcggcacata cgtcccaacc aaattcagcc gattgtaaat aataaactgc ggaatcaaaa
     8221 tcacttgtgc aggaatcatc atcgttacta acatgacgac gaaccagaat ctttttcctt
     8281 tgaaatcgat tctcgataat gcgtaagcaa tacaagtcga gctcagaact gtccctatcg
     8341 tcgaaactgc agagatgaca aacgaattcc taaagaaagt aaaaaatgaa attccagcaa
     8401 accccgccca tccttttgcg taattttccc attgaaaagt ctctggaatc aaattcagcg
     8461 aaccactcat aatctcttga tccgttttaa aagaacctgc gatcatccat aagaccggat
     8521 aaatcatgac tagacctaat agcaaaataa aaccgtattg aaaccatttc gttactgtat
     8581 tattcatttc ttcctcctct cattcacaca acgacccatt tttttgatga tttgaaaatc
     8641 agaaaggtga cagctcccat aatcaacagc atgatccacg aaatagcact agcatacccc
     8701 atagaattaa aagaaaaagc ttggttatac acataaagag cataaaagtt cgtggcatca
     8761 ttcggaccac cttgggtaat gataaatgcc tgcgtaaaag tcataaacgc cgcgattgtc
     8821 tgcataacca agttatacaa aatgatcggc gaaagaagag gtaacgtgat cttgtaaaac
     8881 gtctgccatt tgttcgctcc atcgatctct gccgcttcat aatacgagcc tgggatctct
     8941 ttgatacctg cagcaaagat gatcattgcc gaaccgaatt gccaagcaga catcaaaaca
     9001 agagggatca tgaccagttt ttgatcgcta aaccaggaaa gcgcaggtgc gcctaatcgt
     9061 tccaggaaaa tattcactaa cccgttttta gaaaacaact cccgccaaac tagagcgata
     9121 gaaatactgc caccgatcaa actaggcaca taatacaaag aacgaaagaa agtcgttcct
     9181 ttgatattcc tcgttaaaag ataagcaatc aatagaccaa agatcagttt cacaggtaca
     9241 gatgcaaata catagagaaa agtgactcgg atggagttca aaaaacgggc atcactcagc
     9301 atctttatat aattatccaa gccgatccat gagactggat ttcccaaacg ataatcggtg
     9361 aacgaataat aaagtgacaa gatcatcggt atcactgtta tcaatagaaa tcctaggatg
     9421 aatggagaag caaatacgta accgaccaca ttgtcttgat ccaagaaccg ttttagtttt
     9481 tcttttttca tgccttcctc ctgctgctat cctagaatgt ttgacgcaaa ctcataaaga
     9541 ctctctgctg cttcttctgc tgttacttct tcataaatga ctttttcaac taaaagattg
     9601 tattggtctt gaatttccgg attcaaagca ctatcaaaga cattcacttc gccgttgtcc
     9661 atatcggaaa tcatttctaa ataatcaaat gtcgcttgca aagttgcatc atctgcacga
     9721 gcgagctgtt ctcgaatatt cgacatgatt ggtacaccac gttctccttt taaaatttca
     9781 ttggcttctt cactgttttg aaagaaatca ataaacttag cagcttcttc tttatgggct
     9841 gagctttttg ccatactcag catttgcgaa gaacgtaaag ggataccaga ttctccatct
     9901 gcttttctgc gaggtggatt aatcaactga atctccatat cttcaggagc ccctgacaat
     9961 atttctgtca actggttact tgatagaaac accattgccg cttctctatc cctaaccgcc
    10021 tgaaaagaca gatccgtcgt acttgcagct ccaccacctg gttctggatg ggcccctttg
    10081 tctaccagat ttttacgcag ctggaaaaaa tctgttagat agtctggatt ttcaaatccc
    10141 aagctgttag atagatcttc ccgattataa aaattcaatc ctttctcaac ttgtggtatt
    10201 tgaataatac agccagctat aaaatcttcg aatcttgaaa tagcatagat tcctaattct
    10261 tcagtgattt gatagctgat ttgttcaaat tcatcccatg tccaatttga agctggttca
    10321 gggatattta attgttcaaa tatattttta ttgtaagcaa tcgcaaacga attcaccccg
    10381 ttagacagtc caactaattg cccgtcgtaa gtcgtcgttg ctaaatagga ttcatctgca
    10441 ttagaaatat caattatccc ttgctccaca tattcatcta atggttcaat ctgattgatg
    10501 tattgaggaa attgattgtt cagttggaaa atgtcccaga tatcatctga tgctgctagt
    10561 gtacctaatt ttgtgtaata tccttcataa tcataaaatt cataatcgat cgtcacatgg
    10621 ggattttttt cttcataaag ctcgattact tttactgttg catcgtgtcg gacttgcgaa
    10681 ccccaccaag ccatgttcag cgtgattttt ttgtcatctt cttgcccaca agccgtcaag
    10741 aagaataaca taacacttaa agctaagatg attctcattc ttttcttcat tctctgcacc
    10801 tctacttcca ttgttatttt tcaatatact gtatttttat acagaacata tttattaaac
    10861 gatctttttc aaggggaata aaaaccaaga cttgccttat cgttctgcct aggatgaaca
    10921 actcaatact ttcaagaaaa attagatagt gctgattctt ctttcatcgc taaaaacact
    10981 tcttgcttca atgatgggag gataattacg caaagaaaaa aggatatcag acaactgccc
    11041 aatatccttg acatagctaa ataagcatgc ttcttcgtgt gcgctcttcc ctaaaaaaca
    11101 gaaaaataac tagtaattct gtatgaaatt aggtacaata tacacgtcga tgcacaagca
    11161 ttgactatgg caacttgatt ggtcagttcc cgctgacttt tcaagccccg acaatttagc
    11221 tgctactaaa ttgtcgggtg ccttttttag tttttattcg tttttcattc tatagaaagc
    11281 gcttcaataa atcaagacat ttttttgtta gaatgctaat aataacaaaa ggttttaact
    11341 cttcttatgt acattacagg taaaaaaaca aaaaaatttc tctttttttt gaattctgaa
    11401 caaatagtac tggagtacaa aagacgagga agagccacta tctgctcttc ctcgtctttt
    11461 gattctcacc tgttattcat gattcttttt ctcagtttcc cgatattttt ccattttacg
    11521 actaaaaagc tctccgctac ttggtggcgt atatgtgatg gcatttgctc ctgcttgaat
    11581 ggtctcagca atactttctt ccgttggacc acctgtcgca atgataggaa gttcaggata
    11641 ttttttacga aaatggcgta ctgcttctgc agtttcttta cctgcactga tattgataat
    11701 cgaaatacca gctgctaact tttcatctat ttctgtatat ttcgacgtta ccgtactgat
    11761 aactggaata tcaactactc gacaaacttc ttttactgtc tctaaaggcg taggaccgtt
    11821 caaaacgacc cctaacgaac cttgcgcttc tgcgaacatg ctcatgtagg aagaacgagc
    11881 accttgtgtc aaaccaccac ctacaccgga gaaaactgga atgtcagctg cctcaataat
    11941 gcttttagta atcgctggat gaggtgtaaa aggatacaca gcaattactg cattcgcatt
    12001 tgtattacgt atgatcgcaa tatccgtagt aaagatgatc gaacggatca attttccaaa
    12061 tatcttgatc ccgcttgctt ctaaaatgat ttccggtact cttacgatat cttttctcaa
    12121 ttccgtcatg atttctggcg taaattgttc tgccatcagc cacttctcct ttgctatctc
    12181 cggtcatact gattcaattg atacgtctcg atgacctgga tgattttttg cgcataaccg
    12241 gggtctgtcg cataacctgc atcttgcaat gcttgtgcgg cttcctgata gttggtggcc
    12301 gtaatcactt tttcatacag cgcaggattc caatctactc cttggacgaa cagttgtgta
    12361 tggtcatcca tggactgttc ccatgaatca tacactttga agtctccttg gatagttatc
    12421 cattcttcgt taacaaattc ctttgtttcc aggcttactt tcttctgatc cccataagcc
    12481 ttgatcccga aaagattatt gtatttgcta gccaaggtac tttttcccca atttgattct
    12541 aatatagctt gtcctaaaat gatactagga agcactccat aaccatcttg tagttcttgg
    12601 gcatgcggaa caagccgttc aataaattgc tgatgggatt gcgcttcatt ttcttgctga
    12661 ttatcagtaa aaggagaaga cagattcttc aaggaaaaaa caaaggctaa gagtatcact
    12721 gctacaccgg caaccactgc tggccaacgg atattcttgc gcttttgctt tttccacttt
    12781 tttttcgcca tgatcaattc ctacttttca tttaattcat tcagatattc ttctagcgtc
    12841 aattggtgtt tggtgatata ctcagcgttt tctttaccga cataacgtaa gtgccaaggt
    12901 tcatatgtga tcttagttat atcttcgtgt ccttttggat aacgaacgat aaatccatac
    12961 tgcgcagcat tatctgcgat ccatttagct ccaggctgat ctccgtaact tgcatccaat
    13021 acagtagaag gataactgtt gtaccagttt tgatcgacga catcgactgc cagacctgtg
    13081 tggtgttcgc tgtatcctgg ctccgtaatc gtttctttag taatctttgt cgcctcctct
    13141 tctgatacac cttgacgact catcacatct tggacatttt gttcgaaaac ttgttgttgg
    13201 gatgatacag accggtaagc tgagaccatc actaatggaa atccagctgc ttcagcagcc
    13261 ttggcaaatg cttcatattc tggagcaatg cgtttgtcga tcaagtatcc gttacttaat
    13321 gatgccaatt gagtagactc atcaatttct ttttctaatt tgtgatctgg accaaccaaa
    13381 actagcttcc aatcgtctgt tttaacatct ggcaattgtt tggacgtacg atcttttgtt
    13441 tctttgtcct ttaccttgct gctggttgtt tgactgttct tttctttact agcagttgtt
    13501 ttggtgcttg ttcgttcgac tgcttgattg ccggcttgaa catgcgaatc atcatcgcta
    13561 aaaataacat agcccattgc tgcgatcata atcacaactg ctccaaatcc taaaaattta
    13621 ttcacttgaa aaatcctttc gttgttcttc acgttcccca ttcgcctcat gaacgtaagt
    13681 ttcttccaga ttttcattca cccaatcgag aagttcgatt ttttctcctt cgatctgttt
    13741 ttgaacatct gctggcagac gaaaattcaa aatatcatca tagccccatt catcatattg
    13801 aatacttact ttcaagtcaa ggtatctacc agcctgctga ttatttttca aagggatcag
    13861 ctcgactttt gctgctttgc tgctaagcca tttttgcgcg atgcgtgttt tgatttgctt
    13921 gtactctgca acggcaacgt ttcgtttttc gggaaaaata atcgtttgac gcaaaatctt
    13981 ttgcgttagc atccattcat aatcagtgaa aagatttttt actttctgca tcgcttcaga
    14041 tggcagattt ttctcgccat ctttccattt ttgccattgt tctggactga tcagcaagta
    14101 ttcatctaaa aaattttttt cagtttcaaa ctgttctaat aatacactca taataagatc
    14161 aatatatact tgatgcacgt ttatcccctc cttttaacta ttctacttaa gttttgatca
    14221 aaaagcacct cttaaatcgc tgctttcatt ttttttaatg tttcaagtcc tctcctcttt
    14281 attcttcgtg atttttgtta taataataga cagacaagaa actcaatcca actatgaagg
    14341 agcgttttca gatgaaaaaa tatcaatggg gaatcgttgg tcttggtacc atcgcacatg
    14401 agtttgccga aagcttcaat caagagacga gcgaactaac agcagttgct tccagaactt
    14461 cagaaaaagc ggaaaacttc gctcaccgtt acaatattcc aaaagcttac ggaagctatc
    14521 aagaaatgtt agacgatgct gaaatcgaca tcgtgtacat tgctgtacca aatagacagc
    14581 atatcgacca tatcttggca gcattggaag caggcaaaca cgttctatgt gaaaaagcca
    14641 tcacgatgaa taaaaaagaa ctggctgacg ctatgcgctt agcagaagaa aagaatttga
    14701 tcttagcaga agcgatgaca atcttcaaca tgccacttta tcagcagtta cgctcaataa
    14761 tggatacagg aaaactgggg gctttaaaaa tgatccaagc acctttcggc agttacaaag
    14821 aaccagaccc taaaaaccgg ttcttcaatc cagaattagc tggaggagct ctgttggata
    14881 tcggtacgta tgctgtatct ttcgctcgtt tctttttgag ctctcaacct gaagtagttg
    14941 cctctacaat ggttcctttt gaaacaggcg tggacgaaca atccgtcact atcttgcgta
    15001 acaaagaaaa tgaacttgct gctgtcagct tgacttttca ggcaaaaatg ccaaaagtcg
    15061 gtatcgttgc ctttgagaac ggttatgtga cgattgctga ttacccgcgt gctgatcgtg
    15121 cggagatctt atttacagat ggtacaaagg aattcatcga aagcgggaat acatctgaag
    15181 caatgaatta cgaaataaag aatatggtac acatgattga aggtgacttg cccaatcgct
    15241 ctctcttctt gacaaaagat gtcatcgaaa tcttggatca aatgcaagtt ctatggaaaa
    15301 atatgtaatt ttaaaaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
    15361 acaaaaatag ctcctcctat ttttcgtttg gctggactta ttaccgcaga ggaaagcttt
    15421 tgaacaccgt ttaagaaaga ggttgtgagc ctaccgttca gctccgagtc acaaggagca
    15481 atttcaaaaa acagcttctc atgtttgttg aatattgtga cttgtgaccg aggagttgac
    15541 aggagaacac cgtttaaaga agaggttgtg aaatcagctt tttgacctga atattagctg
    15601 aattcacaac ctctattttt ggattttttg ttgggagaat tctgccttga tttcaataaa
    15661 acttttaaaa gactgcaaaa actggaacaa ttctgctcga tcctcgaatt cagggcgact
    15721 agtcggcaga ggcatttgcc gatacaatac ataaacttct tcaatacgtg ttaaaatttg
    15781 tctgccatca tttgactctg aaaatgtttc tgcagtataa atcaataaac catagatatg
    15841 ttttccataa taagctggtt gctggattct ctctagattt tccagcatgt ctttaatcac
    15901 attggcctgt gctcttctca tagagaagta agtttcgtag tatagcggct gtctgagcca
    15961 gtagttttct tgatgttctc tggcatcttc ttggctttcg cgaatgaatg tcagtaaatg
    16021 ttcgcatttg atctgcacat cttctttatt ttctgataaa agaaattctg ccatttgtct
    16081 caaaatattt cgaaattctt tttcgatctg tatttggttt tccttcagct gcttcgtacg
    16141 atctggcatg taaacatttg caagcaaagc aaatactaat ccaatcgcca ttaatcccgc
    16201 ttcattgccg atcagctgcc aagacatgtt ttcctccact aaataatgag tgaccaaaac
    16261 cgaatttact actatccctt cggttaattt gaagcgagag gcaagcggga tgaacaggaa
    16321 taaaaaaaga ctgaagccaa aaatagtata cccaacagca aaaaaactga acagtgctgt
    16381 tgccgtagct aatataaagg ctgcgattcg attcatgccc gtacgcaatg tagagcgctt
    16441 ggtatttcct acacttaata atgcaatgat ccctgcagct ggccaataca acagcgataa
    16501 gctacccgct gtgaccatcg aaaagaagac actgatcact gttttgactg ttcgcattcc
    16561 tatacgcatt tacttccccc ttttttattt taattatact tgaataatga aaaactagct
    16621 atcagacaaa agtttaggta tgatagtaaa aagaccaaaa aggagaatct ctatgcaatt
    16681 tggccgtttt cgactaggta tgcgtacgat caaaagtgcc ttagctgttt ttttatgtat
    16741 cttgtttttt catttgactc aacgaggaat cccgatgatt gctgcattat ctgctgtttt
    16801 ttctttgcgt caggacttga ctacaaccgt ttcttttgga aagtctagga tcatcggcaa
    16861 tacattaggt ggtacattag ctatcattta tttttttgtc aaaagctatt ttcacaatga
    16921 ttttttggta gaattgatct tgcttcctat tctagttatt attgtgatcg tcgtgtcaga
    16981 tggtattaac aataattccg gtatcatttc cgcaatagct acgttgttgc tgattgcgtt
    17041 gagcatccct caaggcgaat ccgctttgta tgctatccaa cgtgtactag atacttttat
    17101 agggacattc attgcaatcg gtatcaattt ctttcttcgt cctcctgaaa cagaaaagaa
    17161 ggaagaacta tcagaagatt tggtcgaact ccaaaagaaa gaacgattgc taagaacaaa
    17221 tttacaagag atagaagcta agatccaaaa acaaaagaaa aatagcgagg actaattttc
    17281 ttttgcaata aaataaaaaa atggagagaa gaactttaaa aagtcttcct ccatttttga
    17341 ttgaacggtg aagtgtacta ctttattctt ccttcatcga gttttgttct gcctcttttg
    17401 gcgcttcata catatttact tggctagtag tcccacgtgt cgacaaattc tctacgattt
    17461 ccttcaagtc aagtcctgtt gtcgctttta gtgtttcttg agtagaagaa agcaaatttg
    17521 tggcataatt tgtcactcgg ttcgctccac tggtttctcc tgaactgctt cctgtatcga
    17581 caacagagat tttttcgata tttcctagcg gctgtgctgc ttcgcgcatc aattgcggta
    17641 gcatatcgat aaccatactc aagacagctg cttcgccata ttccttgaag gcattggcga
    17701 tcttttgttt tgcttcggct tctgcttttc cttttgctag tgctgcttcg gcttctgctt
    17761 gtccagctaa acgtgtctta ttggcttccg cttctgccag tgcttccaca cggaatcgtt
    17821 ctgcttcggc ttcagtcact tctttgactt tttgagcttg tgcttcttgt tctttagcgt
    17881 accgatcggc atctgctttt ttcttcactt ccgaatcata ttgcttttca cgacgtgtga
    17941 tttctttttc ttccagttcg atttgttttt gacgttctac gattttaatc tgcatttcct
    18001 gttcgattac ttgttgttgt gctcgggcac tttctaaatt gtaggcttgg tctgcttttg
    18061 ctttagcaac atcttgttct tgtttgtagg ttgctaattt cagttctttt tcttttaatg
    18121 attctgcgat ctctgtttgt cgctgtaatt cagctgcttg tgattctttt tctgcttgag
    18181 cttttttgat acgcgtttct tttagagctt ccgcttctgc tatatctgca tctcttttga
    18241 cttgggcgat tcttggtttc cctaaagagt caagataacc gtttttgtct ctgacctctt
    18301 tgatagtgaa agaaacgatg atcaacccca tttttgcaag gtctacagaa gcgacttctt
    18361 gtacgctttg actgaactta tcgcgatttt gatagatttc ttctacagtc atagaaccaa
    18421 gaatcgagcg caagtgtcct tctaatactt ctcttgcttc attttccagt tcttctcttg
    18481 tcttgcctaa aaactgttct gctgctgtag caatctcttc tacagatgaa ccgattttga
    18541 tgatcgaagt accatcacac atcaccggta cgccttgttc cgtatacact tcaggggtgg
    18601 agacgtccaa tttactcgat aatagactga tccgattcga acgttgaaaa actggcaaga
    18661 cgaatgcgcc acctccacgc acaattttga ttttgttatt gctttcatca atgtgcacat
    18721 ttttgcttcc taaataactt ccactgatga tcaacgcttc atccggtttt gctgtctggt
    18781 acttcgctac aaagacgatc agcaacatca gtaaaatcaa agctgcgatt gcgatcgcga
    18841 taaaaacaac tggtatttcc atttaacaca cgctccttta agcttttatc atgctttcat
    18901 aaggcatgac ataacagatt ctttccttga tctcaatgat caatactttc gttccccgct
    18961 cagctgtctg ttcttggggg ctgtaaaaac aagctggacg actaatggaa ccggtaacac
    19021 ttttcaactg aatttctccc atacctcgta cagggatcgg tgtgatcaca acagctactt
    19081 gtccttccag agttttttca gaagacgaca tcgttgattc ggcatgtttc atcggcatca
    19141 atatatagaa attaagcaaa aataccaaca ctatcgatat gcctccacta gcaataaata
    19201 aaaataaaga tgattgatct gttaaacgct cacctagaaa accaaataag cttgtgaaag
    19261 ttaaccaagg gataataagc atcggatcaa gcgggccatc aaaatcgaat acatctccaa
    19321 aaataatcaa taggactgcc aatcctgcac aaatcagcaa tgtataccaa taaatcgtct
    19381 caagtgcgat tccccctatc atatacacgc ctccttccat ttctacgtct atcataccaa
    19441 tgtttgaaaa ttctgtatag cttcttttac cgactcagtg gtgtttttta taggaaggtt
    19501 gtgtttatcg ttgacaattt gttaaatttt tgttttcatg ttaaaatttt cacaataaat
    19561 tctttcgagg tagcctatgt ttcctttttt taagaaaaaa ccattaaagc tccagaacac
    19621 gatcatcctt gtcgtttgtt tctccacatt cgtttctttg attgtttctg ccatattgat
    19681 caggaatttt attctttcga tgaaccgatc tagtgtgtca gataaaatct ctagcattgc
    19741 taaaatcgtt gccaatgata aactcatcca aaaaaagctg cagactggtg acccgacaca
    19801 tgcgattcaa ggaataacaa atgaaatcat gattgcatcg aatttagatt ttatcgttgt
    19861 catggaccct gaaggcattc gatattctca cgcagaccca agttacatcg gtcttccttt
    19921 ctcaagtcat gaagatgtga aaaaagtgat tggaggacaa gaatttttct ctgaaaaaga
    19981 aggaatgtta gggttcggct tccgctattt cgtccctatt tattatgatc aagagattat
    20041 tggtgcagtt tgtgttggct taacaaacaa cacgattgac aatcaagtca aagatggaca
    20101 aaaaatgatt gttttttcat tgattattgg acttagcgta ggcatcatag gcgccgtttt
    20161 tcttgcccaa aaaatgaaaa aagtactgct tggacttgaa ccacaagaaa tagcagaaca
    20221 gttaagtgaa aaaacgatta tcgaaaatga agtagatgaa ggaatcttag ccatctcttc
    20281 tgataaaact atcctcttga tcaatacacc tgcaaaaaac attttctacc aaacagagca
    20341 gctattggat ttcgaagtag gaaaaaaatc agtgataatc tatatgacgt tttgtttaaa
    20401 gagacgattg agcatcaaac gaccgttcgg actcaatcca tgtatttaaa tgggatagaa
    20461 actatttcta gcgttacacc tctttttagc aatgaccgtt ttttaggagc agtcgcaact
    20521 ttacgaaatc gatcagaagt aatgaaatta atggaggagc ttggggggac gaaacaatat
    20581 ataaactcca tgagagctca aacccatgaa ttcatgaata aacttcatgt catttctggt
    20641 ttgattgatt tgaagaagta tgaagaagtc acccatttta tccagcagct aaatcaaaat
    20701 tataaaaaag agattggcca agtctcaagt ctgatcaaag tacctgcaat tgccggtttt
    20761 ttattaggca aaataaacga agccaaagaa caatctgttg aaatgctgtt agaaagcgat
    20821 tcttttatcc ctaaaatgga gatggatgac tccatccatt cacttttgca agtgttaggg
    20881 aacttacttg ataatgcaaa agaagccgtg ctacaaaaac atgaaagaaa cggacaggtc
    20941 cggattcatt taaactatga cacagaagct gaagtattca tcgtgaccgt ctgcgatgac
    21001 ggtgtcggga tatcagaaga aatctcagaa aaaatattta cgctaggttt ttcgacgaag
    21061 ggaatcaatc gtgggtttgg attgaatctc atccattcaa tcgtcaaacg ccacggtgga
    21121 tttttagaat tttccaaaca aacaaatggc ggtacaatcg tctatctaga attaccaaaa
    21181 aaggaagatc aaaatgatga caaatgtcct gataatcgaa gatgatccaa tggttgcaga
    21241 attgaatcgt acttttgtgg aaagcatccc taatatgaac gtaatcgaaa gtttcagaaa
    21301 tgtagaagaa ggaaaaaaat atttcagaca aaaaaacgca gatctgctgc tgcttgatgt
    21361 atacatgcct ggcgaaagtg gtatccattt tttatcttgg cttagacagc aaggaaatga
    21421 tatcccagtg attttgatca ctgctgcaga tgatatcgaa accataaaga atgtgatccg
    21481 ctacggtgcc ttagattatt tgatcaaacc gttcactttg caacgttttc agctggcgat
    21541 cgaaaagtat cttgctttct ctcagacaat ccaaacgact gaaaaagccg atcagaaatt
    21601 gatcgatcaa gtattcaacc acaccactcc cattcacgaa ataccatcat tcatcgattt
    21661 gcctaaaggt ctgtcaaaac tgactttaaa aaaaataagt gcatttattc taaaagaaga
    21721 tactattttt tcaacaaaag aactggctca aaaaagctca ctgtcacgta tatccgtcaa
    21781 gaaatatttg aattttttag tagaacaaga tatattgaac gaaagaatca aatatttgga
    21841 aatcggccgg ccgctaacct gttatgaatt gacaaagaat gggcggaaaa agctcacaga
    21901 ttactgttga gtcatcgaat tatcccatac aaaatagtcc aagtatacag aagtaacaac
    21961 tgtttacttg gactattttt aaacatttta ttgacgaata tccatgtttt cttatcttaa
    22021 ttgacgggct ttaggaagag atacctcatt tttcgttttt ccagtttcta ttatttcacg
    22081 aaagttctcg aaacttgtcg aaatcatatt tgataatgcc tcatctgtat ttgaacctac
    22141 atgcggggtt acaagaactc tagggtacat ttctactaat tgctggatag cagggtctgg
    22201 aatcgtctcc catggcttga aggatcggaa aaaaacctct gtttcatttg caaaaacatc
    22261 ggttgcaaaa ccagctaaat gattgctttt caaagctctt aaaatagctt cattatcttg
    22321 aagctctcca cgggctgtat taatcaagat gctacctttt ttcatttgag ctaaaaatcc
    22381 ttcattgatc atttgatcgt tttcacctgg gatatgaggt acatgaatac tgacaatatc
    22441 gcttttggct aataactctt caagcgagtg gaacgtcaat acttttttag cagcttctgt
    22501 ctgatgaata tcgtagccga tcactttggc tcctagtccc ttaaacaaaa cagcttccgt
    22561 caaccctatc ctgcctgttc ctatgatccc tactgtgcaa tttctgattt cacgactaaa
    22621 catttgctca tccactcgaa aatctttgaa agatgttcgg atcgtcgtat acgcagtatt
    22681 tctcaaaagc atcatggcaa aagtcaaaga taactctgct atcgcatttg gcgaatacga
    22741 tggtacacgg gctactgtca taccaaaatc agctgccgct tgtagatcga tatgattgac
    22801 tcccacagtc cgtgtaaaaa cataacgaat cccatattcc tgcatttttg caagattggt
    22861 ctcatctgct atacaatttc ccctcaacaa tacagcatca tggtcctttg ctgacacgat
    22921 attgtcatgt gtcaacagtt cttcataaag actgagatca taatggtaaa tattcaattt
    22981 ttcaaaaaaa tctatctcgt tcggacgaac accgtaacat gcgattctca tactttcttc
    23041 ctccatttct tatgaaaata aacctatgcc atgaatcatt tgtaatacaa cgatccatac
    23101 aggtgtcagt accacagcaa aaatagttga cagtaaggat gcattggagg ctaaaagtgc
    23161 ctccctatca aaactgatag cataggctgc tgccactgtt gcagctggtg tagccatcat
    23221 gataacgatt gttgccagtg cttcaaaatt gactggtaga atattcgttg ccgtcaaaac
    23281 tgctagaatc acgatattca atgcaggtac aaataccact ttgactagac tgtaatacca
    23341 tgaagttttt tcagatgcag cttttttgaa gcttacttca cctaatgttg cgccgattgc
    23401 tagccacgcc aatggtgaac ttaaaccagc taaataatcc atcggctgaa atagccacgg
    23461 tgcagtctgg tcaattcgca aaaacgctac ttggcttatc tctccttctg cacctgtaac
    23521 tgacacttgt ggcagatacc cttggaacag ccaaatgaaa aggccggcaa aagtagcgat
    23581 aatgattgga ttgacgaaca tcgctttgat atttttagct tccatcttca agccactcat
    23641 ttttatgtat ccataagaat acaaaaagat tcggtagcca atattgaaaa ttgaggaata
    23701 catcacgccg acaggaccat aaatcgcact gacgataggc gttccgaaaa aggtcgtaga
    23761 accaaagatc gtcaggacac gcaacgttgt ttgcttatcc cctttatagc ttaagaaaaa
    23821 aggttttgaa actagaataa gaataatata aataactaat ccccaaatca agacattgat
    23881 tccttgcatc agtaattctg tattgatatc ttgcatgaaa gctcgaaatg ccagtgctgg
    23941 caaagccact gttaagacga ctttcgatag aatttttcca acagattcag aaaaaatccc
    24001 cttttttcta caaacaaacc ctaataatat aataaaaact gttgaagtga ttgcactgac
    24061 aatcgacata tctgtcaaag tcgatcgaaa aatgtcaaat aagttcatct ttctcctcct
    24121 aattatgttc atttattcac aataaaaaaa gcttttattt tgctaatacg tattaacatt
    24181 tttaatttta tctttacatt gttacttatt gaacaatagg aaattaaaga aacttttgaa
    24241 acttatgtaa agtgatttt
//
LOCUS       DAFLWC010000040        23829 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.041, whole genome shotgun sequence.
ACCESSION   DAFLWC010000040 DAFLWC010000000
VERSION     DAFLWC010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23829
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.041"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(53..787)
                     /locus_tag="L1V17_001486"
     CDS             complement(53..787)
                     /locus_tag="L1V17_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBN1236262.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="L1V17_001487"
     CDS             1114..1524
                     /locus_tag="L1V17_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBN1236263.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..2218
                     /locus_tag="L1V17_001488"
     CDS             1517..2218
                     /locus_tag="L1V17_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBN1236264.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2218..3804
                     /locus_tag="L1V17_001489"
     CDS             2218..3804
                     /locus_tag="L1V17_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1236265.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3823..4044
                     /locus_tag="L1V17_001490"
     CDS             3823..4044
                     /locus_tag="L1V17_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HBN1236266.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4041..4802
                     /locus_tag="L1V17_001491"
     CDS             4041..4802
                     /locus_tag="L1V17_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HBN1236267.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5182..5691
                     /locus_tag="L1V17_001492"
     CDS             5182..5691
                     /locus_tag="L1V17_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBN1236268.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5766..6305)
                     /locus_tag="L1V17_001493"
     CDS             complement(5766..6305)
                     /locus_tag="L1V17_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBN1236269.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="L1V17_001494"
     CDS             complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="L1V17_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBN1236270.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7318..8169
                     /locus_tag="L1V17_001495"
     CDS             7318..8169
                     /locus_tag="L1V17_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBN1236271.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8197..8832
                     /locus_tag="L1V17_001496"
     CDS             8197..8832
                     /locus_tag="L1V17_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBN1236272.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8852..9625
                     /locus_tag="L1V17_001497"
     CDS             8852..9625
                     /locus_tag="L1V17_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1236273.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10033..10830
                     /locus_tag="L1V17_001498"
     CDS             10033..10830
                     /locus_tag="L1V17_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HBN1236274.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10808..11221
                     /locus_tag="L1V17_001499"
     CDS             10808..11221
                     /locus_tag="L1V17_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBN1236275.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11205..13850
                     /gene="mutS"
                     /locus_tag="L1V17_001500"
     CDS             11205..13850
                     /gene="mutS"
                     /locus_tag="L1V17_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBN1236276.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13868..15976
                     /gene="mutL"
                     /locus_tag="L1V17_001501"
     CDS             13868..15976
                     /gene="mutL"
                     /locus_tag="L1V17_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBN1236277.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRQTGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15998..16558
                     /gene="maf"
                     /locus_tag="L1V17_001502"
     CDS             15998..16558
                     /gene="maf"
                     /locus_tag="L1V17_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBN1236278.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16643..18631)
                     /gene="treP"
                     /locus_tag="L1V17_001503"
     CDS             complement(16643..18631)
                     /gene="treP"
                     /locus_tag="L1V17_001503"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HBN1236279.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18854..19567
                     /gene="treR"
                     /locus_tag="L1V17_001504"
     CDS             18854..19567
                     /gene="treR"
                     /locus_tag="L1V17_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HBN1236280.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19644..20090
                     /gene="msrB"
                     /locus_tag="L1V17_001505"
     CDS             19644..20090
                     /gene="msrB"
                     /locus_tag="L1V17_001505"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HBN1236281.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20260..20862
                     /gene="ruvA"
                     /locus_tag="L1V17_001506"
     CDS             20260..20862
                     /gene="ruvA"
                     /locus_tag="L1V17_001506"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBN1236282.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20875..21876
                     /gene="ruvB"
                     /locus_tag="L1V17_001507"
     CDS             20875..21876
                     /gene="ruvB"
                     /locus_tag="L1V17_001507"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBN1236283.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21905..22483
                     /locus_tag="L1V17_001508"
     CDS             21905..22483
                     /locus_tag="L1V17_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1236284.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22535..23017
                     /locus_tag="L1V17_001509"
     CDS             22535..23017
                     /locus_tag="L1V17_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HBN1236285.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23134..23508
                     /locus_tag="L1V17_001510"
     CDS             23134..23508
                     /locus_tag="L1V17_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236286.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7781 a         4286 c         5115 g         6647 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcatg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aatatcgggg gcaatttttt gactatgctg attactcctg cgacagtggc
     1741 acttgccatc cctctttata aaaacttccg tttactgaaa gagaattttt atcctgtaat
     1801 ggctgcgatt ttagcaggaa tagtcgcaaa ttgcttggtt agtgtagggt tcggttactt
     1861 cttctctctt cataaagaga tggtgatctc attactacct aaatctgtaa cgacggctat
     1921 ttctgtcgat ttatctcata cgatgggcgg ggtgaatgcc gtgacacttg ctattgttgt
     1981 ctctacaggt atttttggtt cgctgatcgc cactcatatt ttccgcctat tcaagatcga
     2041 aagtccagtt gctcgcggtg tggcgttagg aagtacttct catgctattg gtacagcaaa
     2101 agcaatcgag attggtgaaa tagaaggaat catttccgga cttgcgatat gcgtcaacgg
     2161 aatattgacc gttttattgc taccgttatt ctttcagcct tttgctggct tgttttgatg
     2221 cgaaaaccac tattttatgc tacaataacc aaaacgttcg agcataaaaa aggagggaaa
     2281 gacgtgtatt tgtcttccga gtatcttaaa caatttgata aagatctata ttataagatt
     2341 ctcctcctag aaagttttga ggatcaagct tggcataccg ctgcacaatt agcgcaagtt
     2401 gttcagctgg atgcccgcag cgtgtcgaaa tacctgaacg agctgtctaa aaactatcag
     2461 cagtttagcg gtaagacaca ccctttgttt acaaaaaatc accgttctgg ttataacttt
     2521 tatgatacgc tcgattcaat tgaacatgag cgttttttga tctatctcgt gcaaagtacg
     2581 ctgaaattcc agttgctgca cgacattttt tttgaagaat tccatacaat gtaccaattt
     2641 gcgcaaaagc attacattag tgaatctact gctcatcgaa aaatcaatga atggaaacag
     2701 caactgcaaa cttacggaat tcggctgcaa cgaggtacat atatcgctca aggcgaagaa
     2761 gaaatcattc gactttactt gcatatgaca ttctggcagt tgtttcgagg gaaaatctgg
     2821 ccatttgaaa cgatttctca aatggacgta aagaatatgg cagaacatat catggctttt
     2881 tttaatgttc gtctgaacga gatcaaaaaa agacgattgg aatatatgct aggtgccttt
     2941 tttttaagaa aatcacagaa gcattatgtt gtattgaatg agaaaaaaag acggctgatt
     3001 tctgacaatc tgttgttcca gcgattttgc caggtcatgg agccggtatt tcctaattat
     3061 tttcaagtag aagacgagtt aggcgcatta tttcttgtac tgatgactcg tgaagaatat
     3121 tatagtgatc ctaagatacg gaagaaaatt tttgattttc atcaacaagc aaaaacaccg
     3181 ccctttacag ccctttcaga agcaaaagcc gctctttctc tttatcagga agagcagggg
     3241 ctgccagcag aaaatctaac cttcgaggca gaaaactatt tattcagcag tcattttttc
     3301 gcctatcttt ttcctaatgc gaaagaaacg attgatggca atagtagtga ttttattaat
     3361 catttagtta ttgaaaacaa ggaattgaaa caatggctcg tacatttttt tgaaagtaga
     3421 cacaaacatc ccaatcatct ggcatttaaa aatcatgcgt ttttgatggg gcggtatctg
     3481 actgtgttta aaacattagg agcctttact ccacagcttc caaagatcac gatcctttta
     3541 atgacagatt tcccattatt tgaagagcaa ctgttagagg agggattacg gacatttttc
     3601 cgtaatgagt atcagctgat ttttctgcca acagattatc gggggagaga agttgatctt
     3661 ctgatttcga caagtaaagt ccaccgcaaa ccatgggcgg atcttgacta ttttattgtg
     3721 actgaagaac taaaattaat tgattacatc caactatctc aaaaatttga aatgattcaa
     3781 aaacaaaaac tattaaaaca ataacaaaga aggagaaaaa agatgacatt tgaagaaatt
     3841 ttaccagaat tgaaaaaagg tgcaaagatt attcgtaaag gatggagtgg atttgaactt
     3901 tatgttgttc tcgtatccga tgatgaattt gatggctgtc cggtgacgcc gtacttattg
     3961 atcaaaacaa gtgacgaagg tttttccagc ttcgctccta cagtttgtga tattttagca
     4021 gatgattggg cgatcgtaga atgaaaaacc agtatccaga tctagctaaa caggttgtat
     4081 ttatcacagg agctgcttct ggaattggtg ctgcgcaagc ccgagcgttt cttgaacaag
     4141 atgcttttgt atttggatta gatcaaaagt tcggtaaaat ggaagaaatt tctttgcgat
     4201 ttcctgaaac ttttgcctac gcactaggtg atgttcgaca aatgaaagaa ctccaacaag
     4261 cggtatcgaa atgccaaaat cattttggtg aagttacgat tttactgaat acagcgggga
     4321 tattggatgc ctacaaaccc ttgatggaaa ctgacgaatc gctgtgggat ctgatttatg
     4381 agacgaatgt gaaaagcatg tatcagctga caaaaatcat ccttcctgat atgatccgcc
     4441 aaaaaagcgg aacgatcatc aatatggctt cgattgctgg cttgattgct ggtggaggtg
     4501 ggatcgctta tacaagcgcg aaacatgcga ttgtcggatt taccaaacaa ctcgctctgg
     4561 attacgcagg acagggtatc cgagtaaaag gaattgctcc aggagccatc caaacaccaa
     4621 tgaatgcggc tgattttgaa gggaaaggtg agatggcaga gtgggtggca aatgaaacac
     4681 cagtcaagcg atgggcacag ccggaagaag tagctgagct gacgttattt cttgcctctc
     4741 ctcaagcaag ctacatacaa ggaacgatca tcccaatcga cggcggatgg ttgttaaaat
     4801 aaccttgtgt ttttttcaag cttctgtatg ataaaactaa agagagaaac aacggttgat
     4861 gataaaaaaa gtcgatgact gttcccgaca ttcgatgccg aacagccagt tcaaaaaatt
     4921 ctttttaata atcgttaata ttcgaaacta agcggctttt cacgacctct tgatataaac
     4981 gatattcaaa agcttgcaac tgcggtaaca agtccagcca aatgaaaaat ataaggagct
     5041 atttttattt gaccattctt attacttgtt gcagggcagc tttttcacta ccttctgcga
     5101 cacttcagtt ggaattttct tcccatcctt tggtcgcggt cattaccaag ataaaattat
     5161 cttgcaaagg agaaatagaa catggaaaaa aataataccc gttcagccaa acgctggaca
     5221 acgacagatg tgactcggat ggcgctagtc actggtttat atgtggcagt gacgctggtt
     5281 ttgtctgtct ttagctttgg agtgattcag attcgtctct cggagatgtt caactatctg
     5341 tccttgtata acaaaagata catcgtcgcg gtaacagcgg gagtagcttt ggctaatatt
     5401 gcttctcctc ttggactgat agatgttgca gtaggaagcg tcagcacgct gcttgtattg
     5461 cttatcaact ataaaatcac tagtcgcatc aaaaacatga aaatcaaaat ggccgtgaca
     5521 gcatgcgtat ttgctttttc catgtttaca gtagctggtc agctaacgat tttatatcaa
     5581 ctaccttttt tcttgaattg gtgggtgatt gctttaggag aattggcatc aatgattgtc
     5641 ggtgggataa ttatttattg gatcggtaaa aaagtggatt tgtcaaaata aagatctgtt
     5701 taatttaaaa tagggcagca tggaagagac tgaatgttga gtcttcttcc atgctgcttt
     5761 tttgattaat ttgtatgaag aaatcgattt agccgttttt tcatcaagat accgatataa
     5821 gctgctccag ttgccttgat tgcttccggc agtaaaaacg gcagtagtcc actggcaaat
     5881 gcagttgtaa aagtaagatc accacttatt ttcagccaga tcgttccgca gatcaatgca
     5941 gcaagagagc ccattagatt ggcaaagatt gcatataagt aatgagcatc cgttctttcg
     6001 atcatccaac cagttatcca cgtttgtaag agaaatccaa tcaaatatcc gccagttggc
     6061 ccaaataaaa cagctatacc tccagtcatc cctgaaaata caggaagacc aatcaagcca
     6121 agtaaaagat aaactccaac agatatcaat cctagttttc ttccgagaaa agttgctgtt
     6181 aatccaatag caaatgtttg ccctgtcaaa ggaaccaaac caaaaggaat ggtcatctga
     6241 gaaaggacag aaataatcgc ggcaaattcc gcagcaagta tcaattcttt caatgttcgg
     6301 ttcataacgc cctcttttcg ttaacttaat atttttattt ggttaacgaa attgtaaaac
     6361 aaagtgatta ctttgtaaat agaaaatata aaaaaagacc agctatccaa tagatagcgg
     6421 tctttttcaa gaaagctttt gaaattataa gctttggttg tagtattcaa cgacaagagc
     6481 ttcgtcgatt tctggatata gttcgtcacg ttctggtaaa cgagtcaatg aaccttccaa
     6541 tttttcagcg tcaaagctta cgaatgctgg gcgtccaaca gttgcttcta cagcttcttt
     6601 tactgttacg atgttttgtg atttttcacg aactgagatc acttgaccca cttctacgtg
     6661 gtatgaaggg atatcaacgc gtttgccatc aactaaaatg tgaccatggt taactaattg
     6721 acgtgcttga cgacgagtcg ttgcaagtcc taaacggtaa acaacattgt ctaaacgttg
     6781 ttctagtaag atcatgaagt taacaccatg tttaccttct ttgattttgc tagcttttac
     6841 gaacaagtta cggaattgac gttcgttcat tccgtacatg tgacgaagtt tttgtttttc
     6901 agttaattgc atgccgtatt ctgattgttt gccacggcta ttaggtccat gttgacctgg
     6961 tgcgtaaggg cgacgtgcta attcttttcc tgtgcctgac aatgagatgc ctaagcgacg
     7021 agaaattttc catgatggtc ctgtataacg agacattaaa atttcctcca atgaatataa
     7081 gtttttggag taaaataatc cgttgaaaaa ttcataatca tatagtttgt tcttcaatct
     7141 tcacctttgc agccgcggtt acacaatcga acccgagacg gggcaacaaa ctagggatga
     7201 gttattattt ttctgctgca ttattttaca caaattacag tatatgatag atcatccacg
     7261 aatgtcaaga taattagtac ataaaaacgc tttacaaacc taggctgtct ttataaaatg
     7321 agagggtatg tgcaaatgga aaaaagcgaa ggaagtttaa ggagaaaatc aatgaatccg
     7381 gtatcaccat tatttgagaa aatcgatgct tcaattgaaa agaaggcgaa tctttttgaa
     7441 aacagctttt cacgttacgc tgttcgagcg gttctcgcct gtttgttttt gactttagga
     7501 acggctgtgg catttgcgat cgcgatgaag ggggaagata tcgcgcatgg tctaggaaag
     7561 attttatacg catttatgtt cagctggggt ctggtcatga ttctatacat gaacgccgaa
     7621 ttaggaacat cgaatatgct ttatatgacc gtgggtgttt ttcggcagag acttgcttta
     7681 agtaaggcag ccaagattct atttgcctgt atttttttca atatgattgg cggtatatta
     7741 tgtggatttc taatttctat gactacgcca tttcaagatt taacgttgga caactttatg
     7801 ttagaatcaa tagcagtaaa actagcaaaa ccttcagcaa cgattttggt ggaagggatg
     7861 tttgcgaata tcgttgtcaa taccgctgta ctgatcagca tgcggatgaa agaggatgtc
     7921 ggaaaagtga tcacagtcgt attcatcatt ttcatttttg cttttttagg atatgaacac
     7981 gtgatagcga attttcctgc ctttacgctt acttactttg cttctcacgg acagatggat
     8041 ggaatgacag tcagcaatgt gttacataat ttgttttttg ctttggcagg aaattatatt
     8101 ggtggcggtt tagtaatggg actgggatat gcttggctga atcagtcaaa atcatcctat
     8161 gtggactaaa aagtcgttca ttaaagggga agtgccatgg aagttttagt ttttccaaaa
     8221 aatgaggaaa aagcgttaca aatggaaaag tacatgaaaa atcttttttc ctttgctgga
     8281 gtacctaagc cggaacgcgc tcttttacaa caaccgttac tggatgagag caaaaattta
     8341 tctatttctg aagttttagc ttttgttcat tattattatg aacaaatcga aagagagtat
     8401 cagtatgtag cgatcgattt agtccagaaa aacatcaaac ggcttacatt tgaagactta
     8461 gtcgtattgt tgccactagt tcagaaaaaa gaatggtggg acagcatcga ctcttggaga
     8521 aaagtataca gcacatggtg taaagcctac ccagagcagc gtgaagaagt ctttcaattg
     8581 tttgaaaaaa aggaagattt ttggctacgt cgaatagcaa tcacgttgca attaggttat
     8641 aaacagcaaa cagacacagg actattgatc cgagcaatag acgaagatcg tcaaacaaag
     8701 gaattcttta tccaaaaagc aattggttgg gcattacgcg attatagtaa gaccgatgcc
     8761 gattgggtaa aaagacagct gacaacagat ttgagtaagt tagctgttcg agaggcaagt
     8821 aagtatttat aagaaagcga gacgacaaga gatgagacgc aaattatttg cttttgatat
     8881 tgatggaacg ttgttagatt caaacaaaca agctttagat agcacaagag aagcattgga
     8941 aaaattacgc aaagccggtc atctggtcac gattgctaca gggcggagcc gatttcatgc
     9001 gcaagagatc attcgcgatc ttgattttac gaactacatt ttatgtaatg gagcggccgg
     9061 ttttttagac catgaacaag tatataagaa tttactagat cgcgaccagt tggatgcgtt
     9121 cgttcaagaa gcgcatcatg agcagatcga tacagctttt gtcagcttag acaatatcaa
     9181 gcgttcttct tccaatgatg taacggtgat ggaagaagcg atgcattctt tcggtgctgt
     9241 cttgcctgaa ttagatcagt tttttgcaga ggaacaagaa atataccaag cgttagcatt
     9301 tttcgatcaa acatatgatg ggaagttctc ttcatatgat aaaattcgat ttgtccgctg
     9361 gcatgagaac agtgtagatg tcgtacctaa aaatggttct aaagcagcga caattctgca
     9421 cttagcagaa caagtaggca tccctcatga agacatcatc agctttggcg atggacaaaa
     9481 cgaccgtgaa atgttgcgca tgtcaggaat tgggatagct atggggaatg ctgtgccaga
     9541 agtacaagca gaagctaaga tggtcactga tacaaacgat caggatggaa tttggaaggc
     9601 attgaaagag ttaagcgtga tttaaaagag gttgtgaaaa agctgttctg catcaagtaa
     9661 taagcccagc caaacaaaaa tagctcctcc tatttttcgt ttttctgggc ttattaccgc
     9721 agatgcaagc tttcgaacac cgtttaagga agaggtcgtg acagaagtgg tcagtttcaa
     9781 gaaataagaa gggatttacg aaaattgctt ctcaaatttt tgtaaaatta cggcttattt
     9841 ctgaagaagt agatgaaaca acgtttattc gggaaatggg actgtgacaa gatgtttgtc
     9901 atagtcccat ttttttattt tatttttcaa aactaagaaa taccaggaaa gagttccttt
     9961 tgtttgacct tttctttctt attgaaaaca actataatat agagtgatgt taaaagagaa
    10021 gaggaattta gtgtgcgggt attgtttatt ggtgatgtag taggttcaat gggacgagag
    10081 atgattactg aatatcttcc tagattgaag aagaagtacc gtccgcaagt aacgattgta
    10141 aatggtgaga atgccgcttc tggacgtgga atcacagaaa aaatctataa aaaatttttg
    10201 caagacggcg tagatgtcgt gacgatgggg aatcatacgt gggacaaccg cggaatcttt
    10261 gagtttgtaa atgaagctaa aaagatggtt cgtccggcaa attttccgga agggacgcct
    10321 ggacaaggga tggtctttgt caaagtgaac caagtcgaac tggcagtgat caacatgcag
    10381 gctcgttctt ttatggtgga cttggatgat ccttttcgta aaatgaatga gctggtagaa
    10441 gaagccagaa aacgtacgcc gatcattttt gtagattttc atggagaaac aacaagtgaa
    10501 aaacaagcaa tgggctggtt tttagatggg aaagtttcag cagtggtcgg tacacataca
    10561 cacgttcaga caaatgatgc gcgaattttg ccaagaggaa cagcgtatct gacagacgtt
    10621 gggatgacag gtccctatga tggtattttg ggtatgcgca gagaacctgt aatcgaaaag
    10681 tttctgactg cattaccaaa acgttttgaa gttgtggaac aaggccgatc gattttaagc
    10741 ggctgtatct tggaattgga tgatacgaca ggtcatgcaa aagaaatcca gctgattcag
    10801 atcaacgatg atcgaccgtt catggagtag aaagagaggc agttttttgc agcaggagcc
    10861 ggaaattcaa aaagaagtaa ggaaactgac aaaactttta agagagaatg aaacgatcat
    10921 tcgctacaaa gaacttgaag aaaagatcca gcaaaaccag tatttagctg agttgagaga
    10981 aaaaatcaaa caagcgcaaa aagatgctgt tcattttgcc cactatgaca aaccagcagc
    11041 agaaaaagaa gcaatcaaac aagcggatca attcatgcaa gaatttgatc agcatccgct
    11101 tgttgtagct tatagaaaac agctgttgga agcagatgat ctgcttcatc atttaacaac
    11161 tatgatacaa gaagaaatca atggacaaat agaggaggaa aaacatgcct caaaaaacta
    11221 aaaatactcc tatgatggaa caatatctaa gcatcaaggc ccaataccaa gatgcttttt
    11281 tgttctatcg tttaggagac ttttatgaac tattttacga agatgcgatc aaagcgtcac
    11341 agcttttgga attaacgttg acgagcagaa atcgaaatgc agaagaacct attcctatgt
    11401 gcggtgtacc tcaccatgca gcacaaggat atatcgatgc cttgattgaa aaaggctata
    11461 aagtagcgat ttgcgagcag gtagaagatc caaagacgac taaagggatg gtcaagcgcg
    11521 aagtgatcca gctagtcact cctggtacag tcatggacag caaaggattg tcggcaaaag
    11581 acaacaattt tttaacagct gtagttagtc aaggaaatga atttggcttt gcttatgccg
    11641 atttaagtac gggagaattg aagacggctc ggttgcatga tgaagaagct gttttaaatg
    11701 aagcctctgc attgcagaca aaagaactcg tattaggcag tgagatcact gatacccttc
    11761 gtgaacagct aagcgggcgt ttagggctag tcttttctca acaaaatgag atggaagaaa
    11821 acgcggaatt tagctttttg acaagcgaac tagtcgatcc gctggaaaaa gaagcaaccg
    11881 gcaaactatt gacttattta tcggtgacac aaaagcggag tttagctcat atccaaaaag
    11941 cagtagaata ccaaccagat cattttttga aaatggatta ttattcaaaa ttcaacctag
    12001 aattaagcca atctattcgg actgggaaaa agcacggcac tcttctatgg ttgttagatg
    12061 aaacaaaaac agcaatgggt ggccgtttac taaaacaatg gctagaccgt ccgcttatcc
    12121 aggcaaaaca aattaaagca agacaagaaa tggtcgcttc tttgctagac agctattttg
    12181 aacgtatcga tttgcagtca gcattaacga aagtctatga tctggaacgc ctagcaggtc
    12241 gagtagcttt cggtaatgtc aatgggcgag acttgatcca gctgaaaact tctttagaac
    12301 aagtgccaat gatcagaggg ttgattgaag gaatcgatca aggtcaatgg caaagtctgc
    12361 tttcagaaat gcagccgatg gaccatctcg tccaattgat cgaccaagct atccaagatg
    12421 atccgccgtt acaaataacg gaaggaaaca tcatcaaaga tggattcaat gagcagctcg
    12481 atatgtaccg ttctgctatg agaaacggaa agaaatggtt ggcagaactt gaagcaaaag
    12541 agcgtcaaga aacaggaatc aagaacttaa aaatcggatt taaccgcgtt ttcggttatt
    12601 atatagaaat tacaaaagca aatcttggaa atgcagaact ggagaagtat gaacgaaaac
    12661 aaactttagc aaatgcagag cgtttcatca caccagaact aaaagaattg gagacacaaa
    12721 tcctcgaagc agaagaaaaa tctgttgatt tagaatatca gttgttttta gctgtgagag
    12781 aagaagtcaa aaaggctatc cagccgctac aagtacttgc aaaagcaatc agtgcagtag
    12841 atgtgctaca aagttttgca acgatcagcg aacgctatca gtatgttcgg ccagaacttg
    12901 tcagtgacaa gcatcagctt ctgatcaaag acggacgaca tcctgtagta gaaaaagtat
    12961 taggacatca ggaatatatc cctaacagcg tagaaatggc agaagacgaa atgatcttgc
    13021 tgattacagg accgaatatg tctggtaaaa gtacgtatat gcgacagttg gcattaactg
    13081 ttctgatggc gcaaatgggc tgtttcgttc cggcaaaaca agcagtttta cctatttttg
    13141 atcggatttt tacccgaatt ggtgcaagtg acgacttaat tgctggacaa agtactttta
    13201 tggtagagat gatggaagcc aatcaagccc tgcgttatgc tacgccaaac agtttgattt
    13261 tgtttgacga actagggcga ggaacagcaa cctatgacgg aatggcgttg gcccaagcaa
    13321 tcatcgaata tatccatcgt catgtacaag caaaaacact cttttctact cattatcatg
    13381 aactgacggt acttgagaaa gaacttccgc agcttaaaaa tgtccatgtt ggagccgttg
    13441 aaaaagacgg agaagttgtc ttcttgcata aaatgatgga tggacctgcg gataaaagct
    13501 acggcataca tgtggcaaag atcgcaggat tgccttccaa tctactagaa cgagcagcag
    13561 atatcctgca tacgctagaa aatggcgata acggacacca tactgttcca gctgaagtag
    13621 aagagaaaac taaaacagcc aaacaggagc aaataaaacc acctgcagaa aaagtaaatc
    13681 aagaccatat acaagaccgt gtaaaagaag aaaaccaaca gctttcttta ttcagtgaat
    13741 tatccgaaaa tgaaacagaa gtcattgaat cactgaagca aataaattta ctagaaatga
    13801 cgccaatgga tgcactaaac acattatatg aattacaaaa acaactgtag gaagaaggcg
    13861 gatatcgatg gccaaaatcc aagaattatc tgaacgttta gctaatcaga tcgctgcggg
    13921 agaagtagtg gagcgaccag cttccgttgt gaaagaatta gtggaaaatg caattgacgc
    13981 cggcagtact cagattgata tcttagttga agaagcggga ctgcggacga tccaagtgat
    14041 tgataacgga gaaggcattt tggcagacga cgtagagaat gccttcaagc ggcatgcgac
    14101 aagtaagatc cataatcgcg acgatctttt tcgcatacga acgctgggct ttcgagggga
    14161 agctttgcca agtattgcct ctgtttctga aatgactctg gaaacggcga atcaggaaga
    14221 aaaacaaggc acctatctgt cgctgaaagg cggagaagtt attgagcatc gaccagcacc
    14281 actgcgtcaa ggaacgaaga ttaccgtcag caatctgttt ttcaatacgc cagcccgctt
    14341 gaaatacgtg aaaacactgc acacagaatt agcgaacatc ggggacatcg tcaatcgact
    14401 ggcattgagt catccatcga ttgcttttcg tttagtacat gatggaaaca aaatgctggc
    14461 aactgctgga aatggcgatc tgaaacaaac aattgcggga atctacggat tatctaccgc
    14521 aaaaaaaatg ctgaaaatcg aaggaaaaga tctagatttt gagttatttg gctatgtttc
    14581 attgcctgag gtgactcgtg ccagtaggaa ttacttatcg acgatcatca atggacgttt
    14641 tatcaagaac ttttccttga ataaagcaat cgttgcaggt tatgggtcaa aattaatggt
    14701 cggtcgtttc cctattgctg tattggaaat caaaatggac ccgcttttag tagatgtaaa
    14761 tgttcatccg acgaagcagg aagtccggct gtcgaaggaa aaagaactaa cagagctaat
    14821 tagtaacgcc attcaaaaag cattgtctca agaaaatctg attccaagtg cagcggataa
    14881 tctacggttt aagaaaaaag tacctgatca gcctaaaaca gaacaaatcg aaatcgattt
    14941 gtcctacgct tttgaagaag aaaaacctaa aaagccaagt agtttgaatt ttgatcgaca
    15001 gacaggtacc tttttcgtag aagaactaaa gaacacattt gttgacagaa ttgttgataa
    15061 gtctgtggaa aatgttgaaa actattctgg tttttctgaa gaaaacacca cttatccaga
    15121 aaaaacagcg aaaacggtgg ataagtttgg tgaaaatgtt gataactttg tagaaaaaac
    15181 agtggaaaaa tctgaaaaga aagaatttcc cattgtggat aacatggaga aaacaaatga
    15241 agaacaagca gataaatccg tagaagagga tgaaaagatt tacgaggaag aattgacact
    15301 ccatcctgaa tttgatttca ctcaaggaaa cgacaaaaca ttagaacaag ccatcaagaa
    15361 attagaaacg gaaaaaccag tacaacgttt tcctcagttg gaatattttg gacagatgca
    15421 cggaacgtat ctttttgccc aaagtagcga tgggttgtac atcattgatc agcatgctgc
    15481 ccaagagcgc attaagtatg aatatttccg ggaaaaaatt ggggaagtat ctgatgatct
    15541 gcaagaattg cttgttccat ttgtgttaga ctatccaaac agtgatgctt tgaaattaaa
    15601 agagcaaaaa cacttgctag aagatgcagg gatttattta gaagaatttg gtcaaaacag
    15661 ctttattgta cgggcccatc ctacttggta tcccaatgga gaagaagaat cgattattcg
    15721 ggagatgatc gatatgctgc tgacaactgg aagtgtgagt gtaaaaaaat tccgtgaagc
    15781 aacagcaatc atgatgagtt gcaaacgatc gattaaagcc aaccattatt tgaatgaagc
    15841 acaagcacgt gtgctgctga aggatctggc acgatgcgaa aatcctttca attgtcccca
    15901 tggccgtcca gtattgattc actttaccaa ttcggatatg gaaaggatgt tcaaacgaat
    15961 ccaagacccg cattaagtca aagagaagag ggaaaacatg aagattgtat tagcatccca
    16021 atcaccaaga agaaaagagt tattggctca tatcgtttca gaattcgaga ttgaacctgc
    16081 tgatatcgat gaaacgccat ttccagacga acagcccgtc gattatgttc gtagaatggc
    16141 tgaagaaaaa gcacgaactg tctgggaaca agatgaaaaa gaagaccatt tagtgattgc
    16201 cagtgacacg actgttgttc tcaatcaaga gatcatgggt aaaccagaag atctggctga
    16261 ggctgaattc atgctgaaaa aactaagcgg ggaaacacat actgtatata cagctgttgt
    16321 tttaaaaaca aaggaacgag aagaacggat actagcagaa gcacatgtca ctttttatcc
    16381 tttgacagac gaagagatca aacgctactt ggagacgggg gattatgcgg ataaggcagg
    16441 ggcatacggc atccaaaatg ctgcgagtgt attcgtcaaa gaaatttctg gagattatta
    16501 cagtatcgta ggatttccga ttggtgctgt caatcaggca ctgaaaacat tcatttaaac
    16561 aaaaaagcgg actatctgat tttcgattga aaatccatga tagcccgttt tttttattga
    16621 aaagattact tatctactct gactaagatt ttacttcagc tttaccgact gcttcgcccg
    16681 ggcgaacaag tcctgattgg tcaagagaaa gtcctgcaac tttttcatta ttggtcaaag
    16741 caacaataat gtcagttttc ttgccagctt gttctatttc tggcaaatcc atttcagcaa
    16801 tcagggtctc tggtgtgaca aggtatcctt ctttcacgaa tacattgaaa ggaacaccct
    16861 ttagttcaac agtatctaat cccatgtgaa caagtacttc cagcccctca ttagaaagaa
    16921 taccaatggc atgttttgtt tcaaagacac tcgtcacttt accgtttact ggtgcataga
    16981 ctttgccgtt tgacggttcg acagcataac cgtcacccat cattttttgt gagaaaactg
    17041 ggtcatttac ttcagttatt tccttgatgg tccctgcagc gactgcgaat aatgtttctt
    17101 ttgttgcaac tgccgtacca gttgctgaaa caggttcgaa agactgtggc gttgctgttg
    17161 cgccatttgc tgtttgaagt tgtacatcag cagcattttc aggaacagca ggatcaatct
    17221 tattcaaaat tccctgacgt ctaaagatga tcgtcaagcc aaatggaatg atgacagcaa
    17281 tgatcattgc gatgatgaaa ggtacccatg tttctgcttg gatagctagt attcctggca
    17341 aaccgcctac tccgatcgcg ttagctcgaa cacccatcaa gttagcaaac atgccagcta
    17401 atccagagcc gaccattgca gcgacgaaag gatagacgta tttcaaattg attccgaaca
    17461 tagcaggttc agttacgcct aagtaacaag aaatcattgc tggaatcgag atttgttctt
    17521 cttttttatt cccacgatgt aagaagatga tggctaagac tgcagagcct tgggcgatat
    17581 ttgataaagc aatcatcggc cataaattcg ttgatccgaa atctgcaatc agctgcatat
    17641 cgatggcatt ggtcatatgg tggagaccag taatcactaa aggagcatac aggaatccga
    17701 atacggcact aaacaaccag ctgatagaag acgtcaatcc agtatttacg atatttgaga
    17761 tccagcttcc gactgtccag ccgataggac ctaaaataac gtgtgcagct aaaacagttg
    17821 gtaacaatga aaacaatgga acaaaaatca tcgagatcga ctgagggata tatttgcgga
    17881 agaagatttc tagatacgct aacataaacc ctgccagcat ggctggaata acttgcgctt
    17941 gataaccaat catctggact tgagcaaaac caaaatccca aaatggaata tctgctgcgg
    18001 ctgtggaagc tacactataa gcatttaata attgcggaga aactaacgta attcctaaaa
    18061 cgattcctaa tatttgtgta gtacccatct tttttgcaat actccaagtg atacctactg
    18121 gaagaaaatg gaaaattgct tcaccgggta accacaaaaa ggcattgaca ccattccaaa
    18181 acttcgagtg ttcaacgatt gttccaccaa gactttcaaa ctggatacct tcaagtacat
    18241 ttctgaatcc aaggatcaat ccaccgacaa tgattgcagg aatcagtggt gtaaagattt
    18301 ctgctaaaac ggcaatagca cgttgaacgg gatgaaggtt ttgttttgca gctgcttttc
    18361 cttgttcttt ggaaacccct tcaactccag atactgcaac gaagtcgtta taaaaagtag
    18421 aaacatcgtt tcctatgatg acttggaact gtcctgcatt cgtgaacatc ccttttacgc
    18481 taggtatatc ttcgatcgct ttttcgtccg cttttcctgg atcattcagg acaaaacgca
    18541 tacgagtcgc acaatgacta actgcagcaa tattttcttt tccgccgata tcatgtaaca
    18601 gcttctcggc atctgcttga tattttgcca tatcaataaa cccctttctc ttaacttgtc
    18661 tatgcaagtt gtttcttcat ttactatact ttttttcgga gagaattgca agcgttttat
    18721 taaaaagtac gagagaaaat gatatcgttt taaaaagctt aaaataagct tttcttaaaa
    18781 ataggaacat tgaaatacaa aaagagctgt agtatagtga agaaatgatg gaagaacgag
    18841 tgagggaaaa aacatgaata agttcaatga aattttttta gatttggaac agaaaatttt
    18901 agcgaaagaa tatcctccgc attcgctttt acccagtgag aaccaattga tcaaaattta
    18961 tggtgtttca cgagaaacaa ttagaaaagc gctgaatctt ttgactacgg aaggttatat
    19021 tcaaaaaaaa caaggaaaag gttcgatcgt actggatcgg aatcgcttcg actttcctat
    19081 ttctggattg actagctata aagagctaca ggagacccaa cgtattccaa gtgaaacgat
    19141 catccatacg ttagaagaaa cagaagtgac aaaagcattg aacgagatca ctggctggga
    19201 gatcggtgcg cctgtttggc atttgatacg cgaaagaaaa atcaatggcg aagtagttat
    19261 attagacacc gattatctat taaaggaaat cgttcctatt ttaactccag cacaagcaca
    19321 aggatcgatc tatgaatatt ttgaaaatga gctttctttg acgattgctt acgcgcaaaa
    19381 ggagatcaca gtagaagaag taacggaaat catgaaaaca gcgatggatc ttcacgatga
    19441 cacttatgca gtagtagtca gaagcctcgt tcatctggaa gatacccgct gtttcgagta
    19501 ttctgagtcg gttcaccgat tagataaatt ccgtttcgtt gagtttgccc gacgccgaaa
    19561 agtgtaaata gttcaaaaga aagcaaattg ttggcatctg tccactttgg cgctatgata
    19621 ggatcacaaa gggggcattt ttaatggata aaccaataag accagaaaaa gaagaactga
    19681 aagaaaagtt atcacccatg gcttatgcag tcacacaaga aaatgcaaca gaacgaccat
    19741 ttagcgggaa atatgatgat ttttacgaaa aggggatcta tgtagatatc gtcagcggtg
    19801 aaccgttatt cagctctgca gaaaaatatg atgcaggttg tggctggcca tcattcagca
    19861 aaccaataac gaaaagacaa gtgcgcgaaa aagccgattt ttctcatggc atgcatcgaa
    19921 tagaagttcg aagcaaagaa gcagattctc atctcggaca tgtgtttacc gatggaccag
    19981 tagatcaagg tggtctacgt tactgcatca attctgcctc actgaaattc attccatatg
    20041 aaaagatgga tgaattaggt tatggggaat tcaaatcact tgtagaataa tggaaataca
    20101 caaagagcgg tacaatacgg ggatttactc gatcgtccgc tcttttttta ttcaagcgat
    20161 tgctatttga aagaaacgct ccctagactc cttttttcac aaggtgaaat gtgctacaat
    20221 aaagggaacg tatgtgtgca aaagaaagag gactagaata tgtatgaata tctgacaggt
    20281 gtggttacct ttatcaaccc ctattacata gtagtagaaa ccaatggtat cggctaccag
    20341 atcgcactag gaaatcctta ccgctacagt agcaaactaa atcaaaaaat aaaaatttat
    20401 gtccatcagg taatacgtga agatgcgcat cttctgtatg gatttgattc gctagaagaa
    20461 aagcaactgt ttttgcgatt agtaagtgtt tcaggaatcg gtccgaaaag tgcccttgca
    20521 atcatggcaa gcgaagacca ctccggtttg attcaagcag tagaatccag tgatgtcact
    20581 tatttgacga aatttccagg agtagggaaa aagacagcac aacaaatgat cttggatcta
    20641 aaaggaaaat tcggtgagct gagtatcgat acacctttta gtctatttga tgaagcaaac
    20701 acaaaagacg ctacagctct atctgaagca atggaagctc tctcggctct tggttacagt
    20761 gatcgagaaa tcaaacgtgt agaaaaacaa ttaaaagaag tagataatca gacaacggat
    20821 gagtatctac gccaagcact caagctaatg atgaaaaaat aaggaggaga ccaaatgaca
    20881 gatgaatact tgttatcacc agaatctggc gaaaatgaac tgagtttgga aaaatctctt
    20941 cgaccacagc tgctttctca atatatcgga cagagaaaag tcaaacaaga acttcagatt
    21001 tacatcgaag ctgccagaaa tcgggaagaa cctttagatc atgttctgtt gtacgggcct
    21061 cctggattag gaaaaacgac gatggccatg gtcattgcta atgagatgac cgtaaatatt
    21121 cgtacgacga gtggccctgc tatcgaacgt ccgggtgact tagtagcaat cttgaatgaa
    21181 ctggaagcag gggatgtcct gtttatcgat gagatccatc gattacctag agtggtagaa
    21241 gagatgcttt attcagctat ggaagatttc tatgtagata tcatggtagg acaagggcca
    21301 accgcacatc cggttcattt ccctcttcct ccctttactt tgattggcgc gacgacacgg
    21361 gcaggtatgc tttctgcacc tttacgagat cgatttggca tcatttctca tatggaatat
    21421 tatgacgaac aggatctgca ggagatcgtt ttacgttctt cggatatttt tcaaacagag
    21481 atcattgaag aaggggcatt ggaaattgct cgccgatcac gaggaacgcc tagaatcgct
    21541 aatcgcttgc tcaaacgggt tcgtgatttt gcgcaagtcc aaggagacgg gaaaatcgat
    21601 cgtcctatag cggatcaggc acttactttg ctacaggtcg atcaggctgg attggattat
    21661 gttgaccaga aattgttgcg aacaatgatc gagttatatg gcggcggacc agtagggtta
    21721 agtacgcttt cagtaaacat aggagaagag cgtgagacgg tagaagatat gtatgaaccg
    21781 tatctgatcc aaaaaggatt tttaaagcgt acacctagag ggcgaattgc tactgcttat
    21841 gcctatgaac attttggtta cgactatcat atatgatttt tgcttttaga ttggaggaaa
    21901 atgaatgagt gatacaacac gtacgaaaca attgatcaaa aacgtattga ttgatttgtg
    21961 ccaaacgcaa tcttttcgaa aaatcagcgt ccaaaaaatc gcaaacgaag caaaaatcaa
    22021 tcgacaaaca ttttattatc attttacaga taaatacgat ttgcttcgtt gggtctattg
    22081 tgaggatgca ttgcattatt tagatccaca atgtctttca cttgataatt gggaagagca
    22141 agcattgaaa atgctgaaag caattgctga gaagaaagaa ttttatgcaa atactgtgct
    22201 ttctgaccca gaaattttac aaaaagagtt ttctcaactg atccaaaaat catttatcaa
    22261 gatttttgaa caaatggatg aagaaagaca actttctgca agagacaaac tattttatgc
    22321 tcgttttttt tcttacggtt gcagtggtgt attagtcaat tggatcacga atgaatatga
    22381 agaaacaccg atggaaatcg ctatgcagct tttccgttta gccaaggata cggaattata
    22441 ttcttatcgt ctttatgcaa aagaagagtt ggaagaacag taatagaaaa attttttgtt
    22501 ggaaaagcaa taatcgctaa aaggagatgg ggaaatgaca aaaattttat ttgtttgttt
    22561 gggaaatatt tgccgttcac cgatggcaga aggcttgctg agaaaacgaa tagcattaga
    22621 aggaagggaa gcagaatttt ttgtggattc tgctgctaca agcacgtatg aagttggaaa
    22681 gacaccgcac cctggaacga aaaaaatatt aaaccaagaa aaagtagata tgacgaatat
    22741 ggttgctcgg caaatcacac cccacgattt tgaaactttt gattggatca ttggcatgga
    22801 tcaagaaaat gtagaagaac tgaaacgaag agcaccacgc tcagcgcagg ggaaaatcca
    22861 tttgttttta agtagcattc ctggaaaaga aaaagaaaat gttcccgacc catactatac
    22921 caataacttt gatgagacat atcacttgat cacagaaggc ctgaatcatt ggtggaatat
    22981 ttggattgat gaaaataaaa taacaaacaa tttgtaaagt taacgctttc tttttaaggc
    23041 gatgttagag catttccttg tttttttgta aaatgttagg taaaataaaa ttaattaagt
    23101 aacactttct tagctaaagg aggagtgcat tcgatgaacg aagagacagt atcgccaatg
    23161 aagaagctta cgaagttagt tactcatact tcgtatcaac tttttgattc ttttgtaaat
    23221 gacactgaag aacatgctaa gaatgtacga ttgcaaggaa agtttattct tgagctgcaa
    23281 aaagctgcta ctgaacatag tctagttatc ttacaagtaa gagcaaatcg tttgagtagc
    23341 aagtatgaaa cgatctcagg ctgggtggcg acaaaaacgg tcgaaaaaga ccgagtgatg
    23401 atccgcctac aaaacgaaga gcagcagatc cggatggttc ctgtagaaca aattgaaaaa
    23461 ataacaatcc tttcaccagc aggggaacag gaacggttat caaaataatt tataccagat
    23521 agaaaagcac gtatgagctt gtaccatcaa tcattactaa tcaaaaataa ccgaatgctt
    23581 taagctgata tcagtaaaac ggaacgtttt aggatgagta tcatagcatg acagcattcg
    23641 gttgattagt tgaatcgatt ggatggtaca agtttttttg ataaaaaaag gtcctgctag
    23701 ccggggagct agcaggataa ggagttaaaa atgaaaaagt gttgttaggg ttgtttgttg
    23761 gtatgcttat ataatagtca ttagttgtga atattttgtg acgaaagttt tcgaaagttg
    23821 ttaagtttt
//
LOCUS       DAFLWC010000041        23653 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.042, whole genome shotgun sequence.
ACCESSION   DAFLWC010000041 DAFLWC010000000
VERSION     DAFLWC010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23653
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.042"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..506)
                     /locus_tag="L1V17_001511"
     CDS             complement(<1..506)
                     /locus_tag="L1V17_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1236287.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQVILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSM"
     gene            779..3250
                     /locus_tag="L1V17_001512"
     CDS             779..3250
                     /locus_tag="L1V17_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBN1236288.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(3353..5089)
                     /locus_tag="L1V17_001513"
     CDS             complement(3353..5089)
                     /locus_tag="L1V17_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBN1236289.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(5086..5790)
                     /locus_tag="L1V17_001514"
     CDS             complement(5086..5790)
                     /locus_tag="L1V17_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1236290.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5921..6424
                     /locus_tag="L1V17_001515"
     CDS             5921..6424
                     /locus_tag="L1V17_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBN1236291.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            6384..6722
                     /locus_tag="L1V17_001516"
     CDS             6384..6722
                     /locus_tag="L1V17_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBN1236292.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6743..8161
                     /gene="ffh"
                     /locus_tag="L1V17_001517"
     CDS             6743..8161
                     /gene="ffh"
                     /locus_tag="L1V17_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBN1236293.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            8273..8851
                     /locus_tag="L1V17_001518"
     CDS             8273..8851
                     /locus_tag="L1V17_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HBN1236294.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8855..9376
                     /locus_tag="L1V17_001519"
     CDS             8855..9376
                     /locus_tag="L1V17_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBN1236295.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(9455..10009)
                     /locus_tag="L1V17_001520"
     CDS             complement(9455..10009)
                     /locus_tag="L1V17_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBN1236296.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            10262..10537
                     /gene="rpsP"
                     /locus_tag="L1V17_001521"
     CDS             10262..10537
                     /gene="rpsP"
                     /locus_tag="L1V17_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBN1236297.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            10549..10800
                     /locus_tag="L1V17_001522"
     CDS             10549..10800
                     /locus_tag="L1V17_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBN1236298.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            10925..11716
                     /locus_tag="L1V17_001523"
     CDS             10925..11716
                     /locus_tag="L1V17_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236299.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            11886..12407
                     /gene="rimM"
                     /locus_tag="L1V17_001524"
     CDS             11886..12407
                     /gene="rimM"
                     /locus_tag="L1V17_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HBN1236300.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            12397..13158
                     /gene="trmD"
                     /locus_tag="L1V17_001525"
     CDS             12397..13158
                     /gene="trmD"
                     /locus_tag="L1V17_001525"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBN1236301.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            13294..13641
                     /gene="rplS"
                     /locus_tag="L1V17_001526"
     CDS             13294..13641
                     /gene="rplS"
                     /locus_tag="L1V17_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBN1236302.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            14014..14676
                     /locus_tag="L1V17_001527"
     CDS             14014..14676
                     /locus_tag="L1V17_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236303.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            14755..17982
                     /gene="fss3"
                     /locus_tag="L1V17_001528"
     CDS             14755..17982
                     /gene="fss3"
                     /locus_tag="L1V17_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBN1236304.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITGAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            18096..18410
                     /locus_tag="L1V17_001529"
     CDS             18096..18410
                     /locus_tag="L1V17_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBN1236305.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            18423..18797
                     /locus_tag="L1V17_001530"
     CDS             18423..18797
                     /locus_tag="L1V17_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBN1236306.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            18807..19151
                     /locus_tag="L1V17_001531"
     CDS             18807..19151
                     /locus_tag="L1V17_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HBN1236307.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDVEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            19222..20574
                     /locus_tag="L1V17_001532"
     CDS             19222..20574
                     /locus_tag="L1V17_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBN1236308.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVDKKFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREISDIGGLNVNTEG
                     "
     gene            20634..21776
                     /locus_tag="L1V17_001533"
     CDS             20634..21776
                     /locus_tag="L1V17_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBN1236309.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPVDDGISVAGMLLGNFEQGNRVYEITGTAPTLSTKQGGTKIMLRKNETEYQ
                     EVKPGNSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVKTDDL"
     gene            21801..22055
                     /locus_tag="L1V17_001534"
     CDS             21801..22055
                     /locus_tag="L1V17_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236310.1"
                     /translation="MIGKIQSDPELEEELYRLNFDIRKNGVKVPDDPYVIDEETDARM
                     ELNQVISELERIADFAKEPDIRQYLFEIKAELEIEGITAE"
     gene            22311..23495
                     /locus_tag="L1V17_001535"
     CDS             22311..23495
                     /locus_tag="L1V17_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBN1236311.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATTCGLSRPYLNQIENGGV
                     TASTKTMRKIFDQLESFNPELPLTLLFDYVRIRFPTTDARKIIQEILHLKFDYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKPDDKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNQKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVNNTRLSDRHKKILEQQSMAIENL
                     II"
     gene            23492..23629
                     /locus_tag="L1V17_001536"
     CDS             23492..23629
                     /locus_tag="L1V17_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBN1236312.1"
                     /translation="MKRGIVMEIVKDILLVFGGSMLGVTVMCLMHASAAADRAMEKKG
                     K"
BASE COUNT         7832 a         4218 c         5073 g         6530 t
ORIGIN      
        1 ttcattgatt tgaactcatc catacacaac accgtcggaa ggaagttcat acgtggctgg
       61 taatgcttcg ttgcttcacg caagatccgt gtcaccgtcc catccgagac gaagtacttc
      121 ttagcgatta gtttacgtga ttgattttcg tacagttcca tgagaatcac ctgcttcagt
      181 tcctttgtta gttgatgatg ttcatcaact aagtccgttt tcgcagaaaa ggtccttcca
      241 caatcatggc agagaaaacg ggtacgtttt aattctaaaa tagttaactt ttctttgact
      301 ttcaacatct gagtgcgtgt cgtataggaa ccgttgcgga taatacgaac cgatcgacag
      361 tgttcacaat aggaagaaga gtcatccaat tttcctttaa taaactgcgc ttgaacgcct
      421 ttatattctt tttcaatcag ccattcttca tcaaaaaata aatgtttatc tgttaatccg
      481 agtaattttc tagtatgatt atccattgag agactccttt ggtaggatga cgttttggtc
      541 gactaaattt taccaaaagt gagtctcttt ttgagttgaa acgaagaaaa agtgttagta
      601 gaaaatcgcc ttcgattttc caccaacaca aaatattata gaaccctttt tttttgctat
      661 atgacaggaa tgaaaggtgt ttgcaagctt aatgtgagga acactttcca tatctgttct
      721 atactggata ggagaagttt ggaaatatcc agaaaacgaa atcaatcgag gtagccacat
      781 gaagaataaa tggataaatc gaagtaaaaa aaagaaagta acacaaagat catcagataa
      841 agtcatccgt ctttttccat cgtataaaga aggattaacg gcagatcaag tcaaggaacg
      901 aatagaaaaa ggtgcagcaa ataattcagt cgatcccaca ttcaaaacaa atcagcaaat
      961 cgtattggaa aacatattta cgtatttcaa tttgatcttt cttatcttag ccattttgct
     1021 ttgtttagta gaatcctata agaacttgac ttttttacca gttatcatag ccaatacagg
     1081 aatcgccatt tttcaggaaa ttcgatccaa aaagatcttg gacgaactaa atgttttaaa
     1141 tacagcaaaa gtcaatgtca tacgagacgg gatagaacaa acaatagata tagaagacct
     1201 tgtaatagat gacattgtta ttttagagac tggatatcaa attccagcag atgcagaggt
     1261 cgtggaaggg aaactgcaag ttaatgaggc tttattgaca ggcgaagcag atgaaataac
     1321 caaagaaata ggtgatccat taatgtccgg cagtttcatt gtttccggaa aagcttacgc
     1381 ccgattagac aaagttggag cagattcgta tatttcccag ctgacagtca aagccaagac
     1441 aatgggagaa ggagaacagt cggagatgat tgcttctctt aatcaattga tcaaatggat
     1501 tgggatcatc attattccta tcggtatcct gcttttttct caaagttact tttttaatgg
     1561 aaacacgatc aaagaaagtg tcgttgcaat ggaagcagca ttgatcggta tgatacctga
     1621 aggactgtac ttgctgacga cgattgcatt agcattaagt gcgactaaac tagcaaagca
     1681 aagagttctt ttacacaata tgaaaagcat tgagacattg gcaagggtaa atgtcctttg
     1741 tgtagataaa acaggaacga tcacagaaaa taaaatgtct gttcaaaaaa tgatcgtctc
     1801 taaaaaacaa gaaataatca gtcagtcaga tcaattggaa gcatgcattg ctgactatgc
     1861 aaaagcgatg gcaggagaca atgcaacaat ggaagctgtt aaagcatatt ttacaaaaac
     1921 cactgatcaa tcctatcacc atgttattcc tttttcttct gtccaaaaat tcagcagtgt
     1981 agcgttggca gacaaggtgt atgttttagg agcgcccgaa atggttttgc gcgatcaatt
     2041 gccggaatat gcggaagagt ttgtttcttt cgctgaaaaa ggctatcgcg tgttggtctt
     2101 tggtgtgtac gatgggattc ttgaagaacc agtattgaca gaagcagtca caccattagg
     2161 ctatattctg attgctaatc ctatcagaaa agaagcaaga gccacatttg attacttcaa
     2221 aaaacagcaa gtagccatca aagtgatttc tggagataat ccgctcaccg tatccaatgt
     2281 agctgtccaa gcagggattt cacatgctga tcagtacgtt gatgcatcta aattatcaga
     2341 agaagaatat gaagcagctg tcgaaaaata tacagttttt ggacgcgtca agccagaaca
     2401 aaagaaaatc ttcgttcaat tgataaagcg taacaataca gtagctatga caggtgatgg
     2461 cgtgaatgat attctagcca tgaaagaagc agactgcagt atagcgatgg cttccggaaa
     2521 tgaagccgcc atgcaggcct cacaagtggt cttacttgat tctgactttt cacgcatgcc
     2581 agaagttgtt gcagaaggac ggcgcgttgt gaacaatatt gagcgatcag ccagcttgtt
     2641 tttagtgaag aatattttct cctttttgct ctcactgttt tcagtgatct ttgctctgac
     2701 ctatccttta gaaccatcac aaatcacatt gattagtttg tttactatcg gacttccatc
     2761 tttcttgctt gctctagaag aaaacaaaaa gcgaatcaga gggaaattca tcatgaatgt
     2821 gatggaaaaa gctgtgccag gtggactaac agatatgatc gtagtcggtg cgttggtgat
     2881 ctgcggggtg actttgaatc taaataaaac agatgtttct acagcatcta ccatgctttt
     2941 gattgcagta gggttcctcg ttctctataa aatctgttca ccgctgaata aattcagaag
     3001 tcagatcatt cttttctgtg ctagcggtaa ctttttttcg gtcatctttt tgcataagct
     3061 gttttcaatc accggtatct cagctgtatc acttttgctg ttgagcattc tatttttctc
     3121 ggcagattcg atttttaggc atttgaccac attggtagaa tatttgtttg aacgtaaaaa
     3181 tgaaaaagag caaaagccgt ttagtcgcgt agctaaaaaa tttctatcga tatttaaacg
     3241 agaaaattga cgaaaagtat ctcaaaaaag agtaaaaaag aacaaccact cgtgtatctt
     3301 tcgaagcagg atgagtcatc caactttaaa acgcacgagc agttgctctt ttttacattt
     3361 tcggaatggt aacggtgaaa gtcgaacctg ttccaagatg actgtctaca gtaatcgtac
     3421 cattaaggag ttgcacgtag tcttttacaa tcgctaaccc taatccggtc ccgcctgaat
     3481 gtcggcttcg cgccttgtct acgcggtaaa aacgctcaaa gatccgttcc tgatcctcaa
     3541 tgtcgatacc tataccaaag tcttggacag aaaacgatag atcatctgtt gcctgatagc
     3601 ggataataat ctcgctgtcg ctttttgaat attggacagc attttcaatt agatttttga
     3661 taattggata aaggatatct gttttagtag taaatggttc gttctttcca atcaatcgaa
     3721 tcgtcaaccg tttcttttcg atgattggct gataattttg aacgatttgc tggaaataag
     3781 gttctgtata aattgtctgg atctcgtaag aattctcgcc atcttttgac agctggatga
     3841 tttcccgaat cagtttatct aaccggatcg catctttttg catgatctca agaaaagaag
     3901 tcagagtttg cgggtcatct tttgcaccat ccagtaaagt ctcggtaaaa ccaatcagtg
     3961 aagtcacagg agtttttaat tcgtgagaga cgttgccaac gaaatccttt tgtagctttt
     4021 ctaaacgtcg cactttcgtt aagtcatacg ccacccctag aatctgtccg gtaccttctg
     4081 aattagtaaa gtagcgcaaa ctcaagtcta atgtctgccg accttctgta agggtgatct
     4141 cctgatggat cagcggatgc tcaggagtca cttgatgaat cagctgaatg agttttggct
     4201 cttgaatgac ttctgtgtac cgctgttcag gttgatagct taccacgttt aaatgtagct
     4261 gcatctttgg attaagcagt agtaaacgag aatcagcatc atcaatcagg aatacgccaa
     4321 tcatcagttc gttcagtaac gtatataatt gctcttctgt ggtagtacac gcccgataca
     4381 tcttactcat ttgttcgctc aacgcattaa tcgtctgata caattcttcc cattgatcgg
     4441 gtgtttgcat gattacttcc gcctgattag gattttgcac catttttttt agtacgggca
     4501 gcacggtttt caatggctgg tttttttgat agatcagata atagatcatt cctgcaagaa
     4561 caaggaagaa agacagaaag aagaaaaaga cccaacggcg aaaactctca gttctcggta
     4621 aaaaaccgct tgtcggttct gcgatacgta aaatggcttc taactggcca ctttttttga
     4681 ctggtaatgc gacatataaa agatcctcat tcaaagtagt acttttgcgc aaagcgctac
     4741 ctaggttccc accattcaat acggctttga tttcgggacg ggagtttcgc tgttcattca
     4801 atgtttcatt gtttgtgtca aataagatct ttccagtagc atccattaaa gtaatccgtt
     4861 cgttcgactg atggacgaat tcttccaaag cagttttgtt ttgcgctgct tggaggtttt
     4921 cgacatctaa ttgccggatc agcagttgtg ctttttttgt caggtagctt tcttgctgtt
     4981 ccacgatctg ctgttgaaaa taatgggaaa tcaattgcca gccaccaaaa aacaaactaa
     5041 ctaaaagaat aagaaagaag agacgttcat aaattttttt ccatttcatc gtttgggttc
     5101 ctgaaactta tagccaaatc ctctaatagt caccaagtac tttgggtgtt ttggatctcg
     5161 ctcgattttt tctcgcaaat gactaacgtg tacatctacg attcggcttt gtcctgcgaa
     5221 gtcaaaattc caaatgcggt ctagcaatgt gtctcggtcg atcacacggt cttttcgttt
     5281 catgaaataa acaagtaatt caaattcttt cggtgttagt tcaatcagat ggtcgtctac
     5341 ggtcacttga taattggtca aatcagcagt gatttgtcca atcgatagat attcaggctc
     5401 agcttcatct tttgattgct tacgaggttc aattcgtctg aatattgctt tcatacgggc
     5461 taatacttcg cgaggactaa atggtttggt caaatagtcg tcagcaccta tttctaggcc
     5521 aatgatccga tccacttggt catctttagc cgtcagcatc aaaatcggtg tttcattttt
     5581 ttcttgacgc agccgctgag tgatctccat gccatccatc gttggaagca tcacatctaa
     5641 aatgatgaaa tcaaatgatt gttctaatgc taattctaat ccttcgcctc catctgtggc
     5701 actggttacc ttgtagcctt ctttttccaa attgaacgtc aagagcgtta caatagaagg
     5761 ttcatcatca acaactagta tttttttcat tcaaatctcc tttaaatagg tttcattctg
     5821 tttatatttt agcatagaat cagtacaaag ggctatttta caaaagaaat aaatggtata
     5881 ataggaaggc actttgctga atagaaagga agagcagtca atgattggaa tcagtgcatg
     5941 tttaggcggt ctggcctgtc gctatgatgg acagaaaaaa gaagtaccag aattgatgga
     6001 actagttgaa actggagaag ctgtcatggt ctgtccagaa gtgatcggcg gattaccaat
     6061 tcctagagat cccgctgaaa tcattggtgg aaatggattc gatgtgtgga aagatcaagc
     6121 aaaagtatgg acgacaagcg gcgaagatgt aacggaagcg tacaaaaatg gcgcgatcaa
     6181 agcctatcaa aaattgcagg aaaaacacat tgatctagtc atcatgaagg aaaaaagccc
     6241 ttcatgcgga acccattcga tttatgacgg aagtttttcc ggaataaaaa aaaatggtgc
     6301 cggagtggct actgcttatt ttattcagca aaaaatgact gtgctctctg atgaagaatg
     6361 gctgaaaact agaggtgagc agaatggaaa tcgaaaagac caatcgaatg aacgcgctct
     6421 ttgaatttta ttcgacctta ttgacagaaa aacaaatgaa ctacatggaa ttatattatg
     6481 cagatgattt ttcattaggt gagatcgcgg aagaatacga agtaagccga caagcagtat
     6541 atgacaatat caagcggaca agcaagatct tggaggatta tgaaaaaaaa ctccatcttt
     6601 tttctaatta tattgttcga gaacaggtat tggaaaatat gactgcatat attacagata
     6661 agtacccgga agataaaaaa ctacttgaat atgtacagca aattcaagca atcgaagaat
     6721 aaataaaagg aatgaagaaa atatggcatt tgaaagctta actgaacgtc tccagcaggc
     6781 gatgggaaaa ataagaaaaa aaggaaaagt atcagaagct gacgtaaaag aaatgatgcg
     6841 ggaaatccgc cttgccttac tagaagccga tgttaacttg caagtagtca aagattttac
     6901 taagcgcgta cgcgaacgtg cggtaggggc agaagtgctg gaaagtttat cacctgcaca
     6961 acaaatcgta aaaatcgttg atgaagaatt gacgatcaca cttggttctg aaacagcaga
     7021 gttaaataaa tcaccaaaaa taccaactgt tatcatgatg gctggtcttc aaggggcagg
     7081 taaaacgacc tttactggta aattagccaa ttatttaaag aaaaatgaaa atgctcgtcc
     7141 gctcctaatc gcaggggacg tatatcgacc agctgcgatc gaccaattga aagtattagg
     7201 tcaacagcta gacgttcctg tatttgatat gggaactgaa gtcagcccgg tagagatcgt
     7261 ccgtcaaggg atggagttag caaaagaaaa gaaaaacgac tatgtattga tcgatacggc
     7321 aggacgtctg catatcgatg aaacattgat ggatgagttg aaacaaatca aagaattgac
     7381 gcaaccaaat gagattttgc ttgttgtcga tgccatgact ggtcaagatg ccgtcaacgt
     7441 agctgatagc ttcaaccagc aattaggtat tacaggggtc gtcatcacta aacttgatgg
     7501 ggatactcga ggcggggcag cactatcgat ccgctcagtg acaggcgcac caatcaaatt
     7561 catcggttct ggtgaaaaat tgactgactt agaagtattc cacccagatc gtatggctag
     7621 ccgtatcctt ggtatggggg atatgctgac attgattgaa aaagcgcagc aagactacga
     7681 cgagaaaaaa gcggaagaac ttgcacagaa aatgcgggaa aattcattcg atttcaatga
     7741 ctttattgaa cagcttgatc aagtgatggg tatgggccca ctggaagatc taatcaaaat
     7801 gatcccagga atgaatcaag tccctggaat cgaaaacgtc aaggtagatc caaaagatgt
     7861 tgaacgcaaa aaagcgatgg tttattctat gacgccagca gaaagagcaa atcctgatct
     7921 gttgaaccca agccgtcgtc gccgaattgc tgccggttct ggaaacagtg ttgttgaagt
     7981 gaatcgaatg atcaaacaat tcaaggaatc aagaaaaatg atgcagcaaa tgtccaaagg
     8041 ggatatgaac atcccaggta tggaccaaat gtttggttca ggcgtcaaag gaaaactagg
     8101 caaaatggcg atgaatcgaa tgatcaagaa aaataagaag aaaaagaaaa aacggaaata
     8161 agatgaaaaa aacagcttcg gtacagactg aaaatgtcta ctgccggagc ttttctatca
     8221 gcaattttta ttctttacta atacaattac tctaaacgaa gaggtggcac agatgagatg
     8281 tccgtggagt gaacaaacag aaagtatgcg gcaatatcat gatactgtct ggggtgttcc
     8341 tgaatatgat gaccaaaagc tgttccgaaa attgatgctt gatattaatc aagccggatt
     8401 gagctggcag acgattttaa ataaaagtga agcattcgat gaagcatatg atcgattcga
     8461 tatcaaaaaa gtcgcaaatt atggagaaac aaaaatcagt gaactaatgg aaaacaaagg
     8521 aattattcgt aaccgaagaa aaatcgaagc agccgtccaa aacgccaaag cagtcttgaa
     8581 aattcaagaa gaaatcggca gtttttcaga gtatctttgg tcgttttcta atggaaaaat
     8641 cgttgattct tcttatcatt cacaagaaga agtcccaaca acaagtcctc tttcagatga
     8701 attagcaaaa gatctaaaga aaagaggatt taaatttatc ggaagcacaa caatctatgc
     8761 ttttttagaa gctgtcggga tcatcaatga tcaccttgac agttgtttcc gcaaagaaga
     8821 ggtcgtacgt atcggcagaa agggcgaata aagcatgcga aaaatcatat tttatggtgc
     8881 tataagttta gatggctatt tggcaacgaa aacggatgat cttcaatggc tttttgacac
     8941 tccaacaggt aagcaaacta cttatgaagc tttttatgaa acaatcgata cgaccatcat
     9001 gggcagaaaa acttatcagg aagcaaaaaa atatttggag accgaagcaa tttatccaga
     9061 gaaaaagaat ttcgtttttt ccacccacgc acaattacaa ttgccagatg ctgaggtcgt
     9121 aaacgaagat cctgttgctt ttctaaaaaa tctacaaatg acagaaggaa aagatatctg
     9181 ggttgtgggt ggcggtcgat tgatcaaacc gctattggaa catcaaatga ttgatgaatg
     9241 gtatatccag attacccctg tattattagg ggacgggatt cctttattcc aaaaaggaac
     9301 atatgaagcg cgttttgaaa tgctagacac gacacgattc ggtgaattta tcgaattgca
     9361 ttatgtacga aagtagaagt aaataaaata aaaaaggcaa ctatatgcag aaatgtcctg
     9421 tacatagttg ccttttttat taccgttatg ctttttactc tgttaatttg ttagaaaaat
     9481 ctagatacgc atctaaaatc gtttggaaga aacttaatgt tccttcaacg atattaccat
     9541 tttcatcaat tagattcgca acgtttccga tatatgcttc cggttgctgc aaggttggca
     9601 cattcaaaaa gacaagtgat tggcgtagat ggtggtttgc gccaaagccg ccgatcccac
     9661 ctggtgatgc agtaacgact aaacctggtt tatgatccca aacactgtgt ccataaggtc
     9721 ttgagcctac atctaaagca tttttcaata ctgctggcac agaacggttg tattcaggag
     9781 taacgaaaac gacaccgtct agtcccctca cttcctcacg aaaacgagtc cattcagcag
     9841 gagcctgttc tggagtttcg agatcctcat tgtaaaatgg cagatcatcg atttttacaa
     9901 atacactttc gtacccttca ggaagcaatt tcgcaaaagc ttctgctact tttttgttgt
     9961 aagaatcttt tcttaaacta ccaataaaaa atccaatttt ttttgtcata cgatttttcc
    10021 tccttcaaac tatctataat aatcttacaa aagataagta actggagcaa ataaaaacac
    10081 ttactgacaa aagctacata gaagatagat tacttatttt taacaaaaaa gaagtctaaa
    10141 atcttctatt ttctaaaaaa aatcgaattt aatcaagctg taaagaaaaa aagctttaca
    10201 gggtaaaaaa aaactgttac actacatctt gtgaataaaa caatggaggt ggaaataaat
    10261 aatggcagtt aaaatccgtt taaaacgtat gggttctaaa aagagtccgt tttaccgtat
    10321 cgtcgtagct gattcacgtt ctcctcgtga tggacgtttc atcgaaactg taggtactta
    10381 caatcctttg aaagaccctg cagaagtagt tttaaaagaa gacttagttc ttgactggtt
    10441 atcaaaaggt gcacaacctt ctgacactgt acgtaacatc ctttcaaaag aaggcgttat
    10501 gcaaaaacac cacgaagcta aattctcaaa gaaataaggt gaccggatat gaaagattta
    10561 agcgacttag tcttaacaat cgttcgtccg ctagtcactt atcctgatca agtcaagtta
    10621 gacgtcgtag agtcgaaaga cttttacgag tacaatctaa cagtggctcc tgaagatatt
    10681 ggccgtatca ttggaaaaca agggcgtgtt gctaaagcaa tccgcacaat cgtttacggt
    10741 gttcggatca atgcaccgaa aaaagtgcgt ttgaatatca tcgatgataa ggaaaagtaa
    10801 ataaacgtgc tgtactcgaa ttttcgagtg cagctttttt gtttttttta ttaattgaag
    10861 aaatgattat ttggcaaaac aagcaagaaa gcgtatcctt ataggaggag ggagtgaaca
    10921 gccaatgaga aagaaaatgt tatttattcc atttgctcta ttgttaagcg cttgtagttc
    10981 ggttactcaa gaatcagaca atacacatct atcaagcagt atatctgaaa ctgttaccag
    11041 tccagaaaaa agtagtacca aaacggcttc caccactgaa caaacaatgg ctacctcaaa
    11101 taatgagaaa aagactgctt tagaccagtt gaaagaacaa cagccaaatg ttcccatgcc
    11161 tctagatgta ccagtctctt caggctatct caatatcgca gcgacacata caaagcaagg
    11221 ttattctatt ttatattaca gaacagatcg tcccctcggg ttgaatgctg acgaattgaa
    11281 tcaagaaacg cctattgcaa cctatctata tcaatatggg tttgcttcta gtcaagaaac
    11341 aatccaagtt ttgcagccat ttgagatcga cacaaatggt cagcaagtgg acttaggttc
    11401 tcgaatcaca gggtatcagc aaggtgcagc aggttcaagt tttcttgaat ggcaagaagg
    11461 aaactggcgt attcgaatcc gtgggaataa tatagaaggc caagatccct tactattagc
    11521 taaagaaatc gtagcttatt tggaagaaaa cagtctacca gcacctgaac aatttggtaa
    11581 aattactgtt gatatgggtg atacgacgaa tcgagccgta gaagtaagct ggcaagaacc
    11641 gaaaaatgcc tatacgatca ctcatcaaga tcctatgtct gcgttgaaga tggcagtttc
    11701 tatgaagagg ttgtgaaatc agcgcgctga tctgagccca tcatttaact ccaagtcaca
    11761 ggaagtaatc aaaaatagca cgccgcattt ttgcataatt ttggcttaat accttaaaag
    11821 aaaactagaa ttgcctcttc acacatgcta aaataaaaca gacaaaaaag aaatggggat
    11881 ataagttgac tgaatacttg aatgtaggaa aaatcgtaaa cacacaaggt atcaaaggcg
    11941 aagtccgtgt tatctcaaca acggatttcc cagaagaacg ttacaaaaaa ggaacggtgc
    12001 taacactatt ccaagacgga aaagcacctg tggaattaac agtcaaaagt catcgcaaac
    12061 ataaaaattt tgacttattg agttttgaag gacatccttc tatcaatgat gtggaaaaat
    12121 atcgggatgg catattaaaa gtgtcaaaag acaactctgt agatctagct gaaaatgaat
    12181 tctattacca tgagatcatc ggtctgcatg tattagaaga tggaactgag ttaggtaaag
    12241 taaaagaaat cttgtcacca ggtgccaatg atgtttgggt cgttcaacgt ccgaaaaaag
    12301 ctgatatatt gcttccatat atcgcttctg tcgtcaaaga agtcgattta gaagctggag
    12361 tggtccgtgt agaaattcca gaaggactga ttgacgatga agattgatgt attgacttta
    12421 tttccaagaa tgtttgaagg tcctatgggg gaatccatca tcggtaaggc tgtagataaa
    12481 ggattattag atatcaatat ctctaacttc cgcgattatt cagataacaa acatcagaca
    12541 gtagatgatt atccatacgg cggtggagca ggtatgctgc tcaaagtcca gcccatctat
    12601 gataacatcc aagccattga aaaagctgca ccggatgtca aaaaaagagt aattcttctt
    12661 gacccagctg gtaaacgatt cgatcagaaa atggcagaag aattttcaca agaagaacac
    12721 ttagtattca tttgtggtca ttatgaggga tatgatgaac gtatccgcac attagtgaca
    12781 gatgaagttt ccttaggaga ttatgtcctt actgggggag aattaggtgc gatggtcatg
    12841 atcgatgcaa cagttcggct tttgccagat gtgttaggga atcagacttc agctcaaacg
    12901 gattcttatt caaccggttt attggaacat ccccaatata ctcgcccggc agaatataaa
    12961 gggatgaaag taccagaagt attgacaaat ggaaatcata aattgattga agaatggcaa
    13021 ttaaaagaat cactaagaag gacctatcaa cgtcggcctg atcttttgga aacacttgaa
    13081 tggacacctc aaatgacgaa atttttagaa gaaatcaaga aagaagaaca agaaaaaaca
    13141 gcagatgaag ccaagtgact ttttctaaaa tcttctttac agtaggttga taatatgtta
    13201 gtattttatg gtgagtgcaa aagcacttaa ctattacgat attccgctgt gagaaaagct
    13261 cataagaata tttggaataa ggagaagaaa accatgaatc cattaatcga agaattaaca
    13321 aaagaacaat tacgttctga catcccagcg ttccgccctg gtgacactgt gcgtgttcac
    13381 gcaaaagttg ttgaaggtac tcgtgaacgt atccagttat ttgaaggtgt tgttatcaaa
    13441 cgccgcggtg ctggaatcag cgaaacttat acagtacgta aagtttctaa cggagtgggc
    13501 gttgaacgta cattcccatt gcatacacca cgtgttgcaa aaatcgaagt agttcgctac
    13561 ggtaaagtac gtcgtgcaaa attgtactac ctacgtgcat tacacggaaa agctgctcgt
    13621 atcaaagaaa tcagaagata aacacggaaa acttccttgg aaatctgaaa tttgtgaaaa
    13681 gtccttgtat atcaagggct ttttcttttt tctctatcac agttttaagc catttttggc
    13741 tgttttggac catttttcaa tcatattccc ttaaaaattg tcctagattg tccgacattg
    13801 actatcagtg tcgtcaaaat agggcaaaat ttagtagtca gcttgacgac aaatataata
    13861 cgaaaaatac caaaacattt accgaattta gcaacttttg aacccaagtt tctcaaaggg
    13921 tcagctatta gcaaaaaaga caaaacatgt acttttctac taaaaagttg atgtgatagg
    13981 cttctatcta aataactatt aggagttttt atcgtgaagc aaaatgatgg acgtatcatt
    14041 tggaaaaatc aaagtgagtt aaaactgatt ttaacaatta atgaattcat cgaaaaacac
    14101 ggaattacat ctagccgtca ataccagaaa aagctatcag aaaatccaaa ttctgcacca
    14161 agtatgtggt tcattaacaa aaaatatgga tcatgggaga atttattgat tagtatagga
    14221 cgagaaaata ctgggtatgg aaaatgggct agaatgtcag aacaagaatt attggaaata
    14281 gtagaagcct ttattaagtg cgagaagata acctctcaac gaatgtacga acaaaaatca
    14341 gtagggaaga atattccttc acttagtacc attaaaaaga tgttaggaga tatacgtcca
    14401 ctttttaaag aaaaaaatga tggatctcga tttactgatt tcgaactgct gttagaacta
    14461 aaaaatgaaa taatccgatt aaaactacag gatgatttat caatgacaaa gtttcgaaaa
    14521 ctagttcaat ccccaaaact accatcagtt gatacaatta tgaaaagaac gaacaaaaat
    14581 tgggaggaat tgatggcaga gattggattt gattatcgaa gaatcaaaat ttataagcag
    14641 agaaacaacc tatccaagac aaagaaaact aaatagtatc actctaaatc agacgttcaa
    14701 aattaaaatt tggacgtctt ttttattacc caaaaacgaa aggagattta ttttatgaaa
    14761 aagccaagat ttaagaattg gcgtttgctc gcaacactga gtctattatg ccaaacaatt
    14821 ggtggatcgc ttggcccaac gattgccttt gctgatgaaa ttactcatcc acaaacggta
    14881 actgtggaat tggatttggc tcaccagtat gctgtcgaag gtacatttag cgatggtcgt
    14941 cccatgtcag aagttaccgt tccgcactat gcagtttaca atggtgtgaa gcaagatatt
    15001 ttctgtattg agccaggggt gccgatttac aatgagttca ctcctggtta tgagaaaaat
    15061 ccattgcctg atatgtcgga gaaagcgaaa ttagtttccg ttttatggaa ggaagctggt
    15121 acggatgtgg atacacatat tgtggcccag aagatgattt ggcaagaagt taatggctac
    15181 acgcttcact caattaaacg ttctgatggt agtgcagtaa atatcgcagc cattgagtca
    15241 aaaatcaatc aagccattgc ggattatcaa aagaaaccaa gcttccataa ctccacagtg
    15301 aaaaccgtgt taggtcaatc gactactgtg acagatacga acggcttgaa tttatcggag
    15361 tttgatgaag ttgtcgagaa tatcgcaaat attgattatc gtgtgaacgg caatcaacta
    15421 gtgattactc caaatgccaa ttcaaaagag agtggtgaat taaccctaaa gaagtcagct
    15481 aatacaggaa caccggtagc ttataaaatg gctggtcaac aaactttgat ggcgggggca
    15541 attgataagc ccaataccta cacaatcaaa attgatgtgg aaactgaggg ttctttgaag
    15601 attaaaaaag tcgataaaga aacaggaaat gttgtaccgg gaaccgtttt ccatttagac
    15661 tttggaaaaa cattacctgc aaaagacgtg accaccgata aagaaggcat tgcgacattg
    15721 gatgagattc ctcatggcgc gaaagtaacc attactgaaa aatcagtgcc agctccttat
    15781 acgattgaca ctacaccaat caccgcaacc attaaatctg gtgagactat ttctgtgact
    15841 tcaaaaaata ctcgcgaaaa aggtcaaatc attttgaata aaatgggggt ggaaacagga
    15901 actgatcttt ggaacgacaa atactcatta gccggaaata cgtttgccat tcgcaaagac
    15961 agtccaaccg gtgaaattgt ccaagaaatg accacggatg aaaaaggtca tgcggaaaca
    16021 ccaaaagaga ttgccaatgc gttggaattg ggaacctatt atgtgaccga aaccaaagct
    16081 agtaatggct ttgtgaatac ctttaaacca gtaaaagtcg aattgaacta tgtcaatcaa
    16141 accgtggctc ttgttaccag taacgtaaaa gggcaaaacc aagaaatcac tggtgaaacc
    16201 actttgacaa aagaagacaa agataccggt aatgaaactc aaggtaaagc tgagtttaaa
    16261 ggagctgaat atactctctt tactgcaaaa gatggtcaag cggtcaaatg gagtgaggct
    16321 tttaaaccag agttagtgaa gggaacgaaa gcttctgatg aaacggtgac tttgacttta
    16381 gatgaaaaga atcaagttgc tgttaaacac ttagcgatta atgagtatta ctggcaagaa
    16441 accaaagcac ctgaaggata taccttggat gaaacaaagt accctgtttc catcaaaaag
    16501 gtggatgata acgaaaaaaa tgccgtgatt acccgagatg ttacggcaaa agaacaagtc
    16561 attcgctttg gctttgattt ctttaaattt gctggatcag ctgctgggac tgccgaaact
    16621 ggcttcaatg atctgacctt taaagtatcg ccattggaag gaaccagtga gattacaggt
    16681 gccgaagatg aagcaattac agcttataac gagcaactag gttttgatgg ctatggcaag
    16741 tttgaaaatc ttccttatgg ggattattta cttgaagaag tagaggctcc agaaggattt
    16801 caaaaaatta cgccattaga aatccgttct acttttaaag aaaataaagc ggattacact
    16861 aagagtgaat acatttttac gattaccgaa aaaggacaaa aacaaccaat taaaacggtg
    16921 accgttcctt acgagaaact gacgaataaa gcattttctg ttagcttgaa tcgtttgatg
    16981 ctctatgatt tacctgaaga agaagatagc ttaacttctc ttgggacttg gaaagacgga
    17041 ggcaaagaat tgacagacct tgattctacc gagctagttg ataaattgag ctataacttg
    17101 catgaaatca aagaagactg gtatgtggta gcgcaagcca ttgatgtgga agcgacaaaa
    17161 gctgcccaag aaaaagatga aaaagccaaa ccagtggtaa ttgccgaaac aaccgcaacg
    17221 ttggcgaata aagagaaaac aggaacttgg aaaattttgc ataaattaac cgcagaacaa
    17281 gttttggata aaaccatcgt cttattcaac tatgtgtatg aaaacaagaa accctatgaa
    17341 gcaggtgatg atccagtagc gaaagatgct agcttgaaca atcaagccca aactgtcaat
    17401 tgtacggtgg aacgccatgt ttccatccaa acaaaagccc acctagaaga tggttcgcaa
    17461 acctttactc atggggatgt ggtggatatg ttcgatgatg tgtcgattac ccatgatgta
    17521 ctggatggct caaaagaagc ttttgaaaca attctgtatg cattacttcc ggataatacg
    17581 accaaagaaa tttggaaatc tggcaaaatt gattatgaag tgaatgacaa agaattcact
    17641 aaaaccgtac ttgcggaaaa agtggacaca agtaaatatc cagaaggtac aagttttacc
    17701 ttcaaagaaa ttaactatgg caaagacgga aacatcaatg ggaaacacaa tgaggatcta
    17761 aaagaaaaaa ctcaaacttt aacacctaaa aaagttccga caacaccaag tgcaccagaa
    17821 caaccggaaa taccaactgt tccaagtgac tctcaagaat ctagtcctac agtaaagaca
    17881 ttcccacaaa caggggagaa aaattctaat gttctgctgt ttattgggtt taccttgatc
    17941 tttgcgactg ctgggtatta tttctggaat cgccgaaact aaggtgatgt gatgaaacaa
    18001 ctaaatagga aaaaccaacg tgcgcgaccg cctcctaaaa aaagtggtcg cgctattttt
    18061 gtatccaaaa ctaaaaatga aaagaggaaa agaagatgga attgaaattt gttgtgccag
    18121 atatggccga aacctttgga aagataaggt atgccggcga aggcgaagtt ttaactgaag
    18181 gatatgggcg gaatactaca gtaattggtc gtagttatca tttgtattcc agtaagcaac
    18241 gagccgatga tattgaagtg gtggtagctg cggaagccgg cgaaaaggat tttgatcaag
    18301 atcaaccact aaaagccgtg aatccccatt tggttgccaa aggctatgag attgagaatc
    18361 gtgggtttac cgactacgtg ttgtatgtcg atgatttagt gaaagcatag gaggaaaaga
    18421 agatgagatt aacagaaggt attgttgtag attcaggact aacgtttggg aaattacgat
    18481 tttccgcatt acgccgagaa gtacggaagc aaaatgagga tggaacggtt agtaacgagg
    18541 taaaagaacg gacttataat ttgaaatcct ctgcgcaagg tcgaatgatc caagttagta
    18601 tcccagcaaa tgtaccctta cgcgagtttg cctatgacgc agaggtagag ttggtcaatc
    18661 caatcatgga tacggtcgcc aattatgttt tccgagaagg aactactgtc aattggttca
    18721 ttaaggccga tgatttagtc ttgaaacgac aaccagatca gggaaattct acaaaccaaa
    18781 atgaaggaaa gaaataggtg aagcgtatgg aaattaatgt tgaacatatt ttagattgtc
    18841 tcgatcaata tggaaaaggt gagctaacgg aggaacaact cactaaagca ttaacctatg
    18901 atgaaaaaat gtttctgatt atgcatcaag ggttactgga agtaggtaac gatgtcgaag
    18961 aagattttga tgtactgaat tggttagggg aagaagagtc cttctttatg gttatcgaag
    19021 taaatgaaag tctatgtcga gaagccgaaa ccgtattgga agaaattggt gtggaaatgc
    19081 cggatgccat tgaagttttt ttaaagcaac tagtggaaac gaaacaactc cctatagcag
    19141 taaatgacta gcataactgc ttgaaattgg atcaatgaaa tcctatgaag cttttttcga
    19201 ttggaggtgg aaaccataaa aatgtacaaa gggcatcgta tacgggcagg agatcagcac
    19261 ttggtttatc actttgttct tggctggcta ctcgctctgt tcatcggttg gatgagcgtc
    19321 ttttattttc aagagcttag acaatttgat atttctaagc tatcactttc tactatagaa
    19381 atcgttcgtt ctataaaaga tttaatctat ttgctaggaa gtctcgttct ttcaggaagc
    19441 acgatgttgc tttatataca cttttttcag gatcattggc gcagtttgtg gcatcgacaa
    19501 aagctagccc ggatgattct agaaaatcat tggtacgaag taaaacaaac tcagagtgaa
    19561 ggatttttca aagacctcaa tagtagtcga accaaagaga caatcagtta cttccccaaa
    19621 atctattacc gtatgaagga tggtttactt tctattcgcg ttcaaatttc actgggaaaa
    19681 tatcaagatc agcttttaaa gctggaaaag aagttagaaa gtggtctata ttgtgaacta
    19741 gtagaaaagg aactcaaaga ctcctatgtg gagtacactt tactgtatga tataattgcc
    19801 aatcgaattg ggatagacga agtagtggca gaaagtgggg ctttgcgatt gatgaaaaat
    19861 caagtatggg cttatgattc tttacctcat atgttaatcg ctggcggcac aggtggtggg
    19921 aagacttact ttttactcac tatcatcgag gctttattaa aatctgatgc cgagcttttt
    19981 gttcttgatc ccaaaaatgc ggacttagcc gatttaggta cggtaatgcc tcatgtctat
    20041 tcccaaaagg aggaaatttc tgcttgtgtg gaagatttct atgagcgcat gatgactcgt
    20101 agcaaggcaa tgaaagaaat gcccaactac aaaacaggag agaattatgc gtttcttgga
    20161 cttccaccaa actttttaat ctttgatgaa tacgtggttt atatggaaat gttaacgacg
    20221 aaggaaagtg cggtgatttt gaataagctc aaacaaatcg tgatgttagg tcgtcaatct
    20281 ggtttctttc tgattctagc ttgtcaaaga ccggatgcga aatatttagg agacgggatt
    20341 cgcgatcaat ttaatttccg ggtggctttg ggtcgtatga gtgaactggg atattccatg
    20401 atgtttggcg aggttgataa aaaattcttt atgaagcgta tcaaaggtcg aggctatgta
    20461 gatacgggag ggagtgtgat tagtgagttt tatacgccac ttgtaccaaa aggatatgat
    20521 ttcttaaggg aaattagcga cattggtgga ttaaacgtta atacggaagg ataaaataat
    20581 agtatgtagc ctaggagtgt caagaatcct gggctttttt tacgaggtga tttatgacat
    20641 ttttagattt attcgctggg attggtggct tttgcttagg tatggaacaa gcgggtcacc
    20701 agtgtatcgg cttttgtgaa attgatgatt ttgctcgcca gagttataag gcaatccatg
    20761 atacaagtaa ggaggtggaa atgcatgaca tcacaagtgt atcagacgag tttattcaat
    20821 ctctcggacc agtggatatc ctttgcggtg gatttccgtg ccaagctttt tcaattgcgg
    20881 gaaagcggca aggattttcc gatactcgag gtactttatt ctttgaaatc gctcggttcg
    20941 ccgctattct ccaacctaag tttttattcc ttgagaacgt ccggggatta ctcaatcacg
    21001 aaggaggggc tacgttcgag acgatcctcc gaacgctgga tggattgggg tatgatgtgg
    21061 aatggcaagt gcttaactca aaggcctacg ttccccaaaa ccgtgagcgg atcttcctta
    21121 tcggacattc tcgagacgca tgtaccgaac aagtatttcc tatcattgga tcgtctccaa
    21181 catctgatca aaacatcaga aacttattaa atatcaaccc ttccaatcga ggaatggggg
    21241 gacaagtcta tgggtcagat gacgtagcgc ctaccttgac cggtgatgaa ggaatcaaaa
    21301 tcgcattgcc ggtagatgat ggaatttctg tagcgggtat gttactggga aattttgaac
    21361 aaggcaatcg ggtttatgag ataactggaa cagcgcctac tttgtcaacg aaacaaggcg
    21421 gaacgaagat catgcttcgg aaaaacgaaa cagaatatca agaggtgaag ccagggaaca
    21481 gtgtgaacct ggcttttcct aattccacaa gtcgtcgagg ccgtctggga aaacaaagtg
    21541 tgcatacctt attaacagga gaccaacaag cagtcgtcac ggatcagtat caaattcgaa
    21601 agttaacacc tagggagtgc tggcggcttc agggctttcc ggactgggct tttgatcgag
    21661 cttctcaagt caattcagat agtcagttgt ataagcaggc tggaaattct gtaacagttc
    21721 cggtcatttt tgatattgct agaagattaa aggaggtaaa aacagatgat ttatgatgag
    21781 ttgattgggg aatctactgg gtgattggca agattcagtc agatccggaa ttggaagaag
    21841 aactgtaccg gctcaatttt gatattcgca aaaacggggt gaaagtccct gatgatccgt
    21901 atgtaattga tgaggaaacg gatgctcgaa tggagctgaa tcaagtcatc agtgaattgg
    21961 aacgaattgc ggactttgct aaagaacctg atatccgcca atacttgttt gagataaaag
    22021 cagagttgga aattgagggt attaccgcgg agtaacggcc aaataaacca ctgataggca
    22081 ctgaccgcgg gggatttgcg aagcagaaat cctccgtggt gctgtgcctg tttatggacg
    22141 gcgttagccg gccatgatgt ctcacccccc gtatctaaca ggggggtaca aaaacacaaa
    22201 aaataagcaa gcaacgataa ggaatggctg tcctatcaag gataataagc aatttgtgta
    22261 gatgttaact gatttgaaaa agttaacacc ttaaatttgg aggtgagaac ttggcacaaa
    22321 ggaatttaga ttatcggcta ttaaaagacc ggcgtaatga atatggcgtt tcacaaaata
    22381 aattagctac gacttgtgga cttagtcgcc cgtacttaaa tcagatagaa aatggtggcg
    22441 taaccgcatc gacaaaaacc atgaggaaaa tttttgacca actggaaagt ttcaatcccg
    22501 agttaccttt aacgttactg tttgactatg taaggattcg ctttcccaca acggatgcga
    22561 ggaaaatcat tcaagagatt ctccatttga aatttgatta tatgctccac gaagattacg
    22621 ccttttactc ctatcaagaa caatatgtta tgggagatat tgtggtgatg ttgtcacatg
    22681 aagaagataa aggcgtcctt ttagaattaa agggtcgtgg ttgtcggcag tttgaaactt
    22741 ttttactcgc ccaaaagcgt agctggtatg actttttcga agattgtcta aaagccggtg
    22801 gcgtgatgaa acgcttagac ctggcaatca atgatcgagt tggcctgtta gatattcctg
    22861 atttaacgaa aaaatgtcag aaggaagaat gtatctcctt gtttcgtacc ttcaaaagct
    22921 atcgttccgg ggaactgttg aaacctgatg ataaagatgg tatgggcaat actttgtata
    22981 ttggcagtct taagagtgag gtctatttct gtttgtacga aaaagactat gagcaatata
    23041 tcaagttagg gattccttta gaccagaccg aaacgaaaaa tcgttttgaa atccgactga
    23101 aaaatgatcg agcttatcat gcaattcaag atttgttaaa aggtcgcagt attgaaagta
    23161 ccacattttc cattattaac cggtacttgc gatttgcgga taaggtggaa ggcaaaaggc
    23221 gaactaactg gcccttgaat gaacaatggg ggcgcttcat tggacggaat cagaaggaaa
    23281 ttcaattaac ttctgaaccg aagccttata ccattgaacg aacgttgaac tggcttggac
    23341 gacaagtcgc ccctacgtgg aagatggcca aggagttgga tcggttgaat cagacaacgt
    23401 acattcagga tatggtaaat aatactcgac tatcagaccg gcacaaaaag attttggagc
    23461 aacaaagtat ggcaattgaa aatttgatta tatgaaaaga ggaatcgtga tggaaattgt
    23521 gaaagatatt ttattggtgt ttggtggcag tatgcttggt gttactgtga tgtgcttgat
    23581 gcatgcaagt gcagcggcgg accgagcaat ggaaaagaaa ggaaagtgat gaaatgaatt
    23641 tcggtcaaaa ttt
//
LOCUS       DAFLWC010000042        23652 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.043, whole genome shotgun sequence.
ACCESSION   DAFLWC010000042 DAFLWC010000000
VERSION     DAFLWC010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23652
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.043"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(25..600)
                     /locus_tag="L1V17_001537"
     CDS             complement(25..600)
                     /locus_tag="L1V17_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBN1236313.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(605..1579)
                     /locus_tag="L1V17_001538"
     CDS             complement(605..1579)
                     /locus_tag="L1V17_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleosidase"
                     /protein_id="HBN1236314.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIASALKVNPNIGKHMERFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEEAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(1603..1647)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1862..2830
                     /locus_tag="L1V17_001539"
     CDS             1862..2830
                     /locus_tag="L1V17_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1236315.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            2927..3220
                     /locus_tag="L1V17_001540"
     CDS             2927..3220
                     /locus_tag="L1V17_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBN1236316.1"
                     /translation="MRSAAYGNQRRKNRLALFNDEQQEIGEMTWSDAGPDIMIVDHTF
                     VDPAYRGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            3338..3574
                     /gene="secG"
                     /locus_tag="L1V17_001541"
     CDS             3338..3574
                     /gene="secG"
                     /locus_tag="L1V17_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBN1236317.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3677..4432
                     /locus_tag="L1V17_001542"
     CDS             3677..4432
                     /locus_tag="L1V17_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBN1236318.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            4435..6792
                     /gene="rnr"
                     /locus_tag="L1V17_001543"
     CDS             4435..6792
                     /gene="rnr"
                     /locus_tag="L1V17_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBN1236319.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            6814..7278
                     /gene="smpB"
                     /locus_tag="L1V17_001544"
     CDS             6814..7278
                     /gene="smpB"
                     /locus_tag="L1V17_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBN1236320.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            7580..8299
                     /gene="atpB"
                     /locus_tag="L1V17_001545"
     CDS             7580..8299
                     /gene="atpB"
                     /locus_tag="L1V17_001545"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBN1236321.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            8352..8567
                     /gene="atpE"
                     /locus_tag="L1V17_001546"
     CDS             8352..8567
                     /gene="atpE"
                     /locus_tag="L1V17_001546"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBN1236322.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            8658..9182
                     /gene="atpF"
                     /locus_tag="L1V17_001547"
     CDS             8658..9182
                     /gene="atpF"
                     /locus_tag="L1V17_001547"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBN1236323.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            9169..9711
                     /locus_tag="L1V17_001548"
     CDS             9169..9711
                     /locus_tag="L1V17_001548"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBN1236324.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9734..11290
                     /locus_tag="L1V17_001549"
     CDS             9734..11290
                     /locus_tag="L1V17_001549"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBN1236325.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            11304..12206
                     /locus_tag="L1V17_001550"
     CDS             11304..12206
                     /locus_tag="L1V17_001550"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HBN1236326.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            12229..13635
                     /gene="atpD"
                     /locus_tag="L1V17_001551"
     CDS             12229..13635
                     /gene="atpD"
                     /locus_tag="L1V17_001551"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBN1236327.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            13649..14071
                     /locus_tag="L1V17_001552"
     CDS             13649..14071
                     /locus_tag="L1V17_001552"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HBN1236328.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            14540..14770
                     /locus_tag="L1V17_001553"
     CDS             14540..14770
                     /locus_tag="L1V17_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HBN1236329.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            14867..16168
                     /gene="murA"
                     /locus_tag="L1V17_001554"
     CDS             14867..16168
                     /gene="murA"
                     /locus_tag="L1V17_001554"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBN1236330.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            16181..16357
                     /locus_tag="L1V17_001555"
     CDS             16181..16357
                     /locus_tag="L1V17_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBN1236331.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            16492..16788
                     /gene="yidD"
                     /locus_tag="L1V17_001556"
     CDS             16492..16788
                     /gene="yidD"
                     /locus_tag="L1V17_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBN1236332.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            16852..17319
                     /locus_tag="L1V17_001557"
     CDS             16852..17319
                     /locus_tag="L1V17_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1236333.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            17404..18288
                     /locus_tag="L1V17_001558"
     CDS             17404..18288
                     /locus_tag="L1V17_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBN1236334.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLIGAAANYLAVRQGEN"
     gene            18402..18638
                     /locus_tag="L1V17_001559"
     CDS             18402..18638
                     /locus_tag="L1V17_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HBN1236335.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            18726..18806
                     /locus_tag="L1V17_001560"
     tRNA            18726..18806
                     /locus_tag="L1V17_001560"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18760..18762,aa:Tyr,seq:gta)
     gene            18813..18884
                     /locus_tag="L1V17_001561"
     tRNA            18813..18884
                     /locus_tag="L1V17_001561"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18845..18847,aa:Gln,seq:ttg)
     gene            19010..19180
                     /locus_tag="L1V17_001562"
     CDS             19010..19180
                     /locus_tag="L1V17_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236336.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            19400..20107
                     /locus_tag="L1V17_001563"
     CDS             19400..20107
                     /locus_tag="L1V17_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1236337.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRRDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(20166..20810)
                     /locus_tag="L1V17_001564"
     CDS             complement(20166..20810)
                     /locus_tag="L1V17_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBN1236338.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKNFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSANHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            20937..21224
                     /locus_tag="L1V17_001565"
     CDS             20937..21224
                     /locus_tag="L1V17_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236339.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            21332..21652
                     /locus_tag="L1V17_001566"
     CDS             21332..21652
                     /locus_tag="L1V17_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1236340.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIA
                     LIGE"
     gene            21970..23046
                     /locus_tag="L1V17_001567"
     CDS             21970..23046
                     /locus_tag="L1V17_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBN1236341.1"
                     /translation="MFDQPEAKPREVVFFWTGQLTEKQTEIAKRILCHSEKRHHLIWA
                     VTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNELFLRYRYVFPEEKITLLHGNTA
                     TAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYNGDAGLAHAVQTAIRSNGRFIY
                     LSATPDEKLLKEIKQTFELHKLALRFHRRLLPEPVLVFMNNWRQKCGNKKKINSLVRI
                     IQQLIKENRILLFCPSITMMHRLKITLQEAFPEYEITDVSSQDDQRAKKVQKMREAIY
                     EILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQIAGRADRKGPYTNSRVYFFYE
                     EKTSAIRKACQEIKEMNEEGKQML"
     gene            23043..23652
                     /locus_tag="L1V17_001568"
                     /pseudo
     CDS             23043..23652
                     /locus_tag="L1V17_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
BASE COUNT         7818 a         4125 c         5092 g         6617 t
ORIGIN      
        1 ttttgctaat ccagctctgt ttattcagcc tatttttctt tttgaatata tcaagcgttg
       61 tggcaacata gtgatgacta atgaaacaac gacgatagac aacaaacgat caaggtagtc
      121 tgtacctgcc tgtaccaaga tcacacttgt tgtctgactt aaacctaacc catgtaatag
      181 ctgaacgatc atactggatc ctgaggaggt gatcccgcca aataactgaa cggtaatgat
      241 cgaagaaacg atcgttccag gtaccgacaa aatcaaagcg agtaataaca gtttcaagct
      301 gtttttatct ttgccgagat atcttggcaa aatcaatcca gcaagcaagc ctgtgagaat
      361 ttggattggc gaataataca gagaaaaaat atctgtagtc actccactta aaataccgct
      421 ggacaatcct gtcagcattc caggtacagg cccaagcaat gcaccagcaa aaatcgttcc
      481 gatagaatcg agatagattg gcaaacgaag ccataaagca atcgttcctc caatataatt
      541 gatcccaata cacaaagcca tcactgtaag tacgcgagtt gccattttgt ttttattcat
      601 tttgttagcc catctttaac ctttccaaat ctttcataat cgtttcttct tgtgcattta
      661 aaagaacggt taaaaacttt cggaaaaaaa gacgagtatc tacttttgtc ataattttac
      721 tgttagcagg tttctgccaa aattcataac gatcaaccaa tgtttgtcca cgacttattc
      781 cttgagtttc cacagcagtg aagcttttga aaccttcaca gatggcctcc tcgataaaat
      841 aagcaacagc taacggatca ttgatgacac atcctaaaat tctttcttgt ttccagtgga
      901 agtcaaaata aaaacgagtg atcgctttta gatactctcc ctcttcagga ttcatttgac
      961 agcagtattc gaggatagtc ggtgtcaaga cgatttctct tgtcacatct aacccaacca
     1021 tttctatcgt ttgtttgaga ttctcgaata cataagaagc tgcttcagga tcacaccagt
     1081 aattgtattc agcaactggc gaacagttac catggctttt gtaagttcca cccatcgaga
     1141 caaaacgttc catatgtttc ccaatatttg ggttgacttt caaagcagaa gcgatattgg
     1201 tcaaaggacc caaagcaatg actgatgtat ttgtcttttc tttgaaataa tcagccaaaa
     1261 aatcaacggc atggagaggt tctgcctgtt ttctcaagat catcgggaaa tttgtttccc
     1321 ctaaaccatc cataccatga gtgtcttgtg cactgatgaa aggttgcttc aaaggttttt
     1381 ccattccttg ataaacagga atgtctaaac gatcacagcg ttccaggcat ttcagcacat
     1441 tctgcgtacc tatatctgca gggacattcc cacaaactac ggtaatagca actacttcga
     1501 tatcagggga tttgacagct aatgataaag ctaaagtgtc gtcgatccct ggatcgcaat
     1561 caataattac ttttcgcatt atttccaatc tcctttcttt agagatactt agttttttat
     1621 tctgggaagt ttccgaacca gtccaagacg agcgtcttga ttataatgca cgaaattagt
     1681 atactggctt ttattgcgaa tgtaaatgct ctcttacaag taaatctatt gaggagaact
     1741 ttaagtaaat gatacaatga aaaagaaatg gaatttacgt gtgccgaaaa taaagaatcc
     1801 tatggatcgg tacattggat aatagataga ttatagtttg gcagaaagcg gcgggtgtac
     1861 aatggttatt ttttatttca ttcttattct gataattata gggatcagtt accattttct
     1921 ttcttatttt tatgcaaaga aattagtaag agcgggagta cagagaggat atgactggta
     1981 tgaagacact ggtcatcgtt tgatggaccc tgctgcagtc acgtcagtag aaaaaaaacg
     2041 acaaaaatta gaagaagagt gtgaaagctt ttgggagcag ggaacaccca aaacaatcaa
     2101 aagttatgac gggttgaaac tagctggtca gatgttcatc catccaaata agcagaataa
     2161 atgggtcatt tgcgtacatg attaccgaag cacagggaaa agagacatgt ctcatatagg
     2221 taaaagatat gcagagaaag gattcaacgt tcttgtacct gatttacgtg cgcacggaga
     2281 aagtgaagga gaaatcatcg gaatgggatg gctagatcgg ctagatttaa ttgcctggat
     2341 ccaactcatc ttagatgaac agccgaatgc gtccattatt ttacacggcg gatcaatggg
     2401 agcttctacg atcatgatgg caagtggtga aaaacttcca tcagcggtca aaggatttat
     2461 tttagacagc ggatatgttt ctgtttatgc agaattccga tatatgttaa gtaaaatcac
     2521 tgtctttcct aaaaaaatgg tcatgagata tgcgaatcat tatgcccaga aatacgccgg
     2581 ttactcctta aagcaagcat cagctacgag acagcttggc agcaatcatc tgcctttatt
     2641 agtcatccat ggtgaaagag atcattttgt ccctacagaa gcagcgtaca cgattcaaaa
     2701 tgctacggca ggggataaag cactgctgct tgttccggaa gcagaacact tggaagcatc
     2761 gatgaaagat ccgaaaacct attggacagt gattttttca tttattgaac aaagaataac
     2821 gatgaattaa ttttctcttc ttttttgtaa gtaattcgag gataaataat tgtttataga
     2881 tcaggagact gctaaaataa ggtaggaata aaaaaatatc agttatttga ggagtgcggc
     2941 atatggaaat caaagaagaa aaaatcgtct tgctttattc aatgatgaac aacaagagat
     3001 cggagaaatg acatggtcag atgcgggccc agacatcatg atcgttgacc atacatttgt
     3061 agatccagca tatcgtggtc aaaagttagc tgaaaagcta gtgtatactg gagtagaatt
     3121 agcaagacga gacgggaaaa agatcattcc tttatgccct tatgcaaaaa aagagtttga
     3181 aaagaaacca gaatatcaag acgtcttacg tcagtcataa gaataacagc tgaaagtttt
     3241 gaactttcag ctgttattcc atttatatag agttgtcacg gacttttatc tatgataaag
     3301 ttaaagagac gatatctttt gggaaggagg ctgcgatatg tataatttaa ttttgggaat
     3361 cgtgatcgtt ttatcgattg ttatggtcat tgcgattatg atgcagccaa gcaagcaaaa
     3421 tagtgcagcg agtgcattta ccggcggtgc ggatcaacta ttcggcaaac aaaaagctcg
     3481 cggctttgaa gctgtcatgc agcgatcaac tgcagttatg ggagctatct ggatgatctt
     3541 attatttgtc ctagcatatt tatcttcgaa gtagttgaat aagcctctcg caaaacggcg
     3601 ggcggctttt tttattgcaa agagaacgct taagaagaag ttatgaaaga aactatggta
     3661 aaatgaggcg aaagaggtga gacgagtgag acaattacca aaaccccttt atgcaaaaca
     3721 tggaaagcga gcggttttgc tgcttcacgc ttactcagga agtccaaacg atgttcgaat
     3781 gctcgcacga tttttggaaa aagcagatta tacagtttat gcgccgcttt ttaaaggaca
     3841 cggaacaatg gagccatatg atatcttgca agaaaaagca gaaagctggt gggcagacac
     3901 taaaaaagcc atccattttt tacagtctga gcagttttct gatattgccg tattaggatt
     3961 atcaatgggc ggcatctttg ctgtacgagc actagaagaa gaatcagtga ttggcggcgg
     4021 ttttttctgt tcgcctttgt ctcctgtaaa aacaaacgtg cctgaaaact ttgaaaaata
     4081 cgtacgtcaa gtgctgaaga cagcaggtaa atcagagaaa gaaatcaatg aaaaagcagt
     4141 tgcttaccgc tcgttagctg aacaacaatt aatggatata caagatcagg cagcaatcgt
     4201 agaaagtagg ttgtcagata tccaacagcc gatattttta gctcaagctg ggaaagatga
     4261 aatgatcgac cctaatggcg tatttgaaac tgcacgcaag ttgagccgtc agcgagtgac
     4321 acttcaatgg tatcctgaaa gtggtcatgt gattacagtt ggtacagcaa gacgcgaatt
     4381 agaaaaagac gtcttggaat ttttagaaaa attaccttgg aatgaggaat aaatatgaca
     4441 aaagaaacga taaaagagaa aattctcttt ttcatggaaa gcagtcgcaa acgcagtttt
     4501 tctatggaag aaatcgctga aggtttaggg ttccaaaaaa gcgatgattt taaattacta
     4561 gtacaaacga ttgctcaaat ggaaagagaa cagagtatag ttttcaataa aaaaggaaaa
     4621 gtgaaacttc ctttaaaacc aatcctgatc gaaggaacat ttcgagcaaa tgaacgagga
     4681 tttggatttg taacgattga tcccgaagaa gatgacatct atatcccaaa agaagcgact
     4741 ggttttgcaa tggatggaga caccgtagca atcgatatca tgaagcgagc aaatacagat
     4801 atggatcgcg gagcagaggg gaaagtagtc gagattcgag accgggcgac tactcagtta
     4861 gcaggggaat tcgttgctta ttcagaagaa gaaatacaag aaacagatct ttacggcgtt
     4921 gttatcccga aagatagaaa gctcaaccaa tttaaagtat atgcagcagc agagggagtt
     4981 cgtccagttg acggaagtat tgtgctgatc gaactgaccc attaccctga aaaagggtat
     5041 gcgactagtt tagaagggat aatcaagcaa gtgattggtc ataagaatga ccctggcatg
     5101 gatatcctct caattgtcgt ggctaatggt atccctacga aatttcctga tgatgtattg
     5161 tctgaagcag atgaagttcc agatcaaatc agcgaaaagg atataactgg acgtagagat
     5221 ttaagaaatc agctcattgt tacgattgat ggagaagatg caaaagatct agatgatgca
     5281 gttacggtta aaaaattaga taacggtaat tattttcttg gagtacacat tgcagatgtt
     5341 tcttactatg tgacacaagg cagtcaattg gacagagaag catatgaaag agggacaagt
     5401 gtatatttga ctgatcgagt aattccgatg atcccgcaac gtttatcgaa tggtatctgt
     5461 tcactgaatc cccatgttcc aaggctgacc atgagttgcg aaatggagat tgatccaaat
     5521 ggacaagtag tctctcatga tattttccca agtgtgatcc aaacaacaga acggatgacc
     5581 tacacagctg tcaatcaaat cttagaagat caagacgaag aaacgatgca acgctatgct
     5641 cagctcgtac ctatgttcca agaaatgggt gaattgcacc gaatccttga aacgatgcga
     5701 atcaaacgtg gcgcgatttc ttttgaggat cgcgaagcga aaatccttgt tgatgctgaa
     5761 ggacacccaa atgacatcca gctaagaagc agaggaattg gtgaacgctt gatcgaatct
     5821 ttcatgcttg cggccaatga aacggtagct gaacattata ataaattaaa tctgccgttt
     5881 atttaccgaa tccatgaaca gccaaaagaa gaaaaaatgc agcgcttctt tgattttgct
     5941 tcagctttgg gcattctggt ccgaggaacg aaaggaacga tcacaccaaa agatttacag
     6001 catgtgatcg aaggagtaga agacaaacca gaagctgcag ttatcaatac tatgttgcta
     6061 agaagcatgc aacaagcacg ctattcagaa gacaattttg ggcattatgg cttagcggca
     6121 gattactaca cacactttac atctcctatt cgacgctatc ccgatctaat cgtccatcgt
     6181 ctgatccgtt cttacagtga agataaaagt gaaagcaatc aaagttcgtg ggctgcggaa
     6241 cttcctgaaa ttgcagatca tagttctaag atggaacgtc gtgcagtaga aacagaacgt
     6301 gaagtagatt ccatgaagaa agcagaattc atgatggaca aagtgggaga agaattcgat
     6361 gggatcatca gctctgttgt gaaattcggc ctgtttatcg aactgccgaa tacagtagag
     6421 ggattgatcc atatcaatga attgaaacag gactacttcc attttgttga aaatcattta
     6481 gctcttgtag gtgaaagaac tggtctgact tttaaaatcg gacagaaagt gcgagtaaaa
     6541 gtagtcaaag ctgatccaga tgaacgagca gtagattttg aacttgtttc cgcagaagag
     6601 gttacagcgt tggaacggcc aaaaacacga aatggaaaat caggaaaacg cgaaggaaaa
     6661 caagcaggaa aacgcccaga aagaaatggc aagaagaaca aacgatatag cgatagtaag
     6721 caaacgttcg gtaagaaaaa agggaagaag ccattttaca aaggtgttaa aaagaagaaa
     6781 aagaaaaaat aaaatgagtt ggaggaaaca gctatgccaa aaggcgaggg aaaattaatt
     6841 gcacaaaaca agaaagctcg ccatgattat tcgatcatcg acacgatgga agcagggatg
     6901 gtcttgcaag gaaccgagat caagtcgata cgaaacagcc ggatcaatct aaaagatgga
     6961 tttattcgcg tccgcaacgg agaagctttc ttgcataatg ttcatatcag tccttatgaa
     7021 caaggaaata tttttaatca tgatccgttg cgcacgagaa agttattatt acacaaaaaa
     7081 caaatcatcc ggcttgaaaa tgaattgaaa aatactggaa tcactgttgt tcctttaaaa
     7141 gtctatattc gtaacggcta tgccaaggta ttgattggtc tggcgaaagg gaaaaaatct
     7201 tatgataaac gggaagattt gaaacgaaaa gatatcgatc gacaaattga tcgaacatta
     7261 aaaaatttct ctagataatt tcattatcct ttttcgcata ttcggtgctt ttgcttttac
     7321 ttaatgataa aatttgttag catttaatct gataaaacat gattatcata ggttttttct
     7381 tagatcagga gcaccgtgta taaagaaaaa ttcgcttcgt ttttgactga aataaaaaag
     7441 tgtctaattt tcatgaaaat gttttgaatt ttctgtttca tggtggtatg ataccgtgtg
     7501 gttagaaacc gattggaaaa aaccagatac gcacatgaat tgattttatg tgaatttcgg
     7561 ggaaaagagg tgaaatggat tggatgaacg ctcgctaacg ttccacattg gaccaatttg
     7621 gtttgatggt acagtttgta taatggtgtt actgacctgt ttgattgttt tcttcttagc
     7681 ttactttttt acaagaaatc ttaagttgaa accaacaggc aaacaaaatg cgatagaatg
     7741 ggtcattgat tttagtcgag gaatcgtaac agataatctg cctagaaaag aattgagcaa
     7801 tttccatttg ttggcattta cattgttttt atttgttttt gttgcaaaca acatcggttt
     7861 agtaacaaaa atcgttttac ctaacgaaac aacactttgg aaaagcccga cagcagaccc
     7921 gtttgttact ttaactttgg catttataat gatcttactt actcacttat tcggggtgaa
     7981 aaagttaggc ttcaaaggat atttcgtaaa ttcgttcttg aaaccctata gttttatgtt
     8041 tccgatgaaa ctgattgaag aatttacaaa cttattaaca cttgctttac gtctttatgg
     8101 gaatatttat gcgggggaag ttttgctaac cttgattgca aaaatgatga caagcttagg
     8161 ctggttctca ttaccattag caattccatt agagatggtc tggatcgcgt tctccttgtt
     8221 tattgggagc atccaagcat ttgtctttgt cactttgtca atggtttata tgagccataa
     8281 gattgaagta gaagaataat actcggttaa aaaacaaact actatttatc tattttagga
     8341 ggaaaacaat tatgaattat atcgcagcag caatcgcaat catgggagca gcaatcggag
     8401 ccggttatgg taacggtcaa gttatctcta aaacaatcga atcaatggct cgccaacctg
     8461 aaatgtctgg tcaattccgt acaacaatgt ttatcggggt agctctagtt gaagctgttc
     8521 ctatcttagg ggtagttatc gccttgattc tagtttttgc cgtttaattg aatcagtatt
     8581 aaggcagaaa caacatcgtt tgttactgct tttttacatg gaaactagaa atactccaaa
     8641 gaaaggaagg ctcgcctatg ctgaatcaat tggcaattgc agaagttggc aatgcgatgt
     8701 taggtaatat catcgttgtc agcggctcat ttttgatact actggctctc ttgaagcact
     8761 ttgcttgggg accaatcagc gatattttga aaaaacgtga agacaagatc gccaatgatt
     8821 tagattctgc agaacaatct cgcatcaact cagcgaaaat ggaacaagaa cgcgaacaac
     8881 aattgttagc ctctcgttct gatgcagctg atatcatcaa aaatgcgaaa gaaagtggag
     8941 aattaagccg ccaaaatatt ttgaaggatg ctcaagaaga agcagctcgt ctaaaaagca
     9001 aagcccaagc tgatatcact gtagaacgtg attcagcgct gaactctgta aaagacgacg
     9061 ttgcagaact ctctcttcaa atcgcggaaa aaatcttgaa caaagaatta tctccagaaa
     9121 tgcatgaatc attaatcaat caatacattg aaggtctagg ttcttcaaat gaaactagat
     9181 aaatatacag taggaagacg ttacgggaaa gctttatttg aactggcgat cgattcaaat
     9241 caagcagaag aaatctatca agatctcgta agtttacgtc aaatctatga acaagtacct
     9301 ggattaggga atatgttaag tgatgttcgt ctagaacctc atgaaaaacg agaaatcatg
     9361 gacaagcttg tcagcggtta tgatgggatc gttaaaaact ttttagaagt tgtttatgag
     9421 tataaccgaa tggatgacct tttgttcatg atcgaagaat atgaacgtcg atatgatgaa
     9481 catcaagggt tactattggg aagtgtcaca acagcagtcc cactttcaga cgaacaacga
     9541 atacaattag aaaagaatgt tgcaaaaaca atggactatc aatcagttga attaaaacaa
     9601 atcgttgatt cttctattat tggtggcgcg attgttgaag ccaaccatcg agtaatcgac
     9661 ggaagcattc gcacgcaatt agaaaaaatg cgtaatcaat taaacagata gtacaaagag
     9721 gtaggtgaat cgaatggcca tcaaagcaga agaaattagt gccttgatta aagaacaaat
     9781 tgaaaattat caaaacgtgc tttcagtcga agaaatcggt accgtaactt atgtaggtga
     9841 cgggatcgct cgtgcacatg gtttagaaaa cgcgatgagt ggtgagttgc ttgaattttc
     9901 aaacggctca tacggaatgg cgcaaaactt agagtcaaat gatgtaggta tcattatcct
     9961 tggcgatttc gagtccattc gtgaaggaga taaagtaaaa cgaacaggta agatcatgga
    10021 agttccagtt ggagaggcct tgatcggtcg ggtagtcaat ccgctaggtc aaccaatcga
    10081 cggactaggt gaaatcgtta ctgacaaagc tcgtccagta gaagcgatgg caccaggtgt
    10141 tatgcaacgt aaatctgtta acgaaccaat gcaaacaggg ctaaaagcga tcgacgccct
    10201 tgtgccaatc ggacgcggac aacgtgaatt agtcatcggt gaccgtaaaa cagggaaaac
    10261 ttctattgcg atcgatacga tcatcaacca aaaaggtcaa gatatgatct gtatctatgt
    10321 agcaatcgga caaaaagatt ctacagttcg tacacaagtt gaaacattga aaaaatatgg
    10381 cgcaatggat tacacaatcg ttgtgaatgc cggtgcgtct caaccagcac cattgcttta
    10441 tatcgcacca tatgctggta ctgcaatggg tgaagaattc atgtacaacg gtaaacatgt
    10501 attgatcatt tttgatgatc tttcaaaaca agctgttgct tatcgtgaac tttccttgct
    10561 acttcgccgt ccaccaggtc gtgaagctta tcctggggat gttttctact tgcactcacg
    10621 tttattagaa cgtgcagcaa aattaagtga tgatttaggt ggcggttcaa tgactgcctt
    10681 accatttgtt gaaacacaag ctggagatat ctctgcttat atcccaacaa acgttatttc
    10741 gatcactgat ggacaaatct tcttagaaag cgacttgttc tacgcaggta ctcgtccagc
    10801 ggttgatgcc ggactatctg tatctcgtgt aggaggttct gcgcaaatca aagcaatgaa
    10861 aaaagttgct gggactttac gcctagactt agcaagttac cgtgaattag aagcatttac
    10921 acaattcggt tctgacttgg atgcagcaac acaagcaaaa ctaaatcgtg gacgccgtac
    10981 agtagaaatc ttgaaacaaa aattgcatgc accgctagct gttgaaaaac aagtagtgat
    11041 tttgtatgct ttgacacatg gattcttaga tagtatccct gtagacagta ttttagactt
    11101 cgaacatgaa ttattcgaat atctggatac caatcattca gatatctttg aaacaatccg
    11161 tacaacaaaa gatcttccag aagaagaagc gttgaacagt gcgattcagg aatataaaga
    11221 catgttctta gctacaaaag gaagtaattc ctctacagaa gataaattga aatccattca
    11281 aaatgcatag tgaggtgaga tgaatgggtg cttcattaaa tgaaatcaag acacgtatcg
    11341 cttcaacgaa aaaaacgagc caaatcacgc gggcaatgca gatggtgtct gcttctaagt
    11401 tgacaaaatc tgaagcttct tcacagaagt ttcaggttta tgcaacaaaa gtaagagaaa
    11461 tcgttacgca tttgactgct actcagttaa atgatattgc ctcagaaaat cctagagggg
    11521 atatcaatta caacagcatg ctgctcagcc gtcctgtgaa gaaaactggt tatatcgtca
    11581 tcactgcaga tggcggttta gtcggtggat ataacagctc gatattgaaa caaacgatgt
    11641 ctattttaga agaagaccac caatcacccg atgattacgt gatgatcgca attggcggaa
    11701 ctggtgcaga cttctttaaa gcacgcggta tcaatctagc atatgagctg cgcaatctat
    11761 ctgatcagcc aagctttgat gaagtccgca aaattgtaaa tatggcaaca actatgttcc
    11821 aaaacgaagt attcgatgaa ttatacgtat gttataacca tcatatcaat tcgctaacta
    11881 gtcagtttcg tgtagaaaaa atgctgccaa tctcagactt agatccagaa gaagcaacga
    11941 ctttcgaaca agaatatatt tttgaacctt caaaagaaga aatcttgtct cagttattgc
    12001 ctcagtatgc tgaaagtttg atctacggtg cgatcgttga cgccaaaaca gcagaacatg
    12061 ctgctggtat gacagcaatg aaaacagcaa ctgataatgc tgctaatatc attgatgagc
    12121 tgacggtttc ttataaccgt gcaagacaag gggctattac ccaagaaatt accgaaattg
    12181 ttgccggagc ttcggcacta gaatagtatt gagattggag gaaaaaagat gagttcaggc
    12241 aagattgttc aagtaatcgg tcccgttgtc gacgtggaat tttctttaga ccaatcctta
    12301 ccagatatca acaacgcatt agttgtttat aaaaatgacg aaaataaatc aaaagttgtt
    12361 cttgaagcag cgttagaatt aggggacgga gtgatccgga ccattgcgat ggaatcaaca
    12421 gatggtttac aaagaggaat ggaagtcatt gatacaggca aagcaatctc tgttcctgta
    12481 ggtaaagaaa cattaggtcg cgtattcaac gtactaggag atacgatcga tttagaaaca
    12541 cctttcccag aagatgcgga aagaagcgaa attcataaaa aagcaccagc ctttgacgaa
    12601 ttaagtacaa gtacagaaat tttggaaaca gggatcaaag ttatcgattt gcttgcccca
    12661 tatttaaaag gtgggaaagt cggactattc ggtggtgccg gtgttggtaa aaccgtactg
    12721 atccaagaac tgatccataa tatcgcccaa gaacatggtg gtatttctgt atttaccggt
    12781 gtaggtgaac gtactcgtga aggtaatgac ttgtattatg aaatgaaaga ttcaggagtt
    12841 atcgaaaaaa cagccatggt gttcggacaa atgaacgaac caccaggtgc acgtatgcgt
    12901 gttgctttga ctggtttgac gattgcggaa tatttccgtg atgtagaagg tcaagatgta
    12961 ctgttgttta tcgacaacat tttccgtttc actcaagctg gatctgaagt atcagccttg
    13021 ttaggacgga tgccttctgc ggttggttat caaccaacat tggcaacaga aatgggtcaa
    13081 ttgcaagaac gtatcacatc tacgaaaaaa ggttcgatca catcgatcca agcaatctat
    13141 gtgccagccg atgactacac tgacccggcg ccggcaacag cattcgccca tttggatgcg
    13201 acaaccaact tggaacgtaa attaacagaa caagggattt atccagcggt agatccattg
    13261 gcttcttctt caagtgcttt agcacctgaa atcgtgggag aagaacatta taaagtagca
    13321 acagaagtcc aacacgtatt gcaacgatat cgtgaattac aagatatcat tgctatctta
    13381 ggtatggatg aattatccga tcaagaaaaa gtgttagttt ctcgtgcccg cagagtccaa
    13441 ttcttcttgt cacaaaactt taacgtggct gaacaattta ctggtcttcc aggttcatat
    13501 gtccctgtag aagaaacagt gaaaggattc cgcgaaatct tggaaggcaa atacgatgat
    13561 cttcctgaag aagctttccg aagtgttggc cgaatcgaag acgtcgtaga aaaagcgaaa
    13621 acactaggct actagaaagg ggtgccccat ggatcaatat ttaacagtaa atgtggtaac
    13681 tcctgccggt ttggtctatg atcaccatgc agctatcgtc gttgcacgta cgacagctgg
    13741 tgagcttggg attttgccta aacatgcacc aatcatcgtt ccattgacga ttgatgaagt
    13801 tcgtgtaaaa cgaacagatt cagataccca cgtcgattgg atcgctgtta atggcggaat
    13861 catggaagtt cgtgataatg ttgtttcaat cgttgctgat agtgcggaac gtgaacgtga
    13921 tatcgatgta tctcgtgcgg aacgtgcaaa acaacgcgca gaacgccaaa tcgaagaagc
    13981 aaaagcaaaa caagatacga acgaattgaa acgggcaact gttgcgttgc accgagcaat
    14041 caatcgtatc aaagtatcta agcactcata aaatgagatg cggatgttta tccgtgttta
    14101 agaacagtaa aaagaggtta tgacagaagt ggtcagcttc aagacataag aaggaattta
    14161 cgaaaattgc ttctcaaatt tttgtgaaat ctcagcttat ttttcgaaga agctacttct
    14221 ggaacaccgt atatcagagg ttgtgaaatc agcgttttgt cctgagtatt agagaaacaa
    14281 atggaaaata gttcctcata ttttgccgtt ttttgagcta ataccgaggg tcagatgatt
    14341 gaacaccgtt tatttggaat aagggactgc gacaagactt ttgtctcagt cccttttttt
    14401 gcatattttt agcatttatt tcctaaaaaa tgtaagggga ttcctatatt tttaagtata
    14461 cttgtttttc cttttataca ttttatggta ttatcatttt attagttatt ataaaacaat
    14521 cgttagaaag gacgtcatta tgcaagtata cggaattgat gcggtgcttc gaatcgtgag
    14581 tcatttggcg tttatctact tagccttctg gtctttacgt tcgttacgca ttgaaacttt
    14641 tttcagacca atgcataata cgcaaattag aatggcaatc gtactttttt caattttttt
    14701 agggtacact gcaagtaatt ttttcttaga ggttatcgct ttatgccgaa atcttttcgt
    14761 tagcctgtaa attttaaaaa aaggtactat tttaaaagca aggatgttat aatagaaaag
    14821 attttgagta agtgtatgct cattggaatt ttttggaggg aacaacatgg aagagatcat
    14881 cgtaagaggt ggcaatcaat taaatggaac agtaagaatt gaaggagcta aaaatgctgt
    14941 tttgcctatt ttagctgcta gtttgttagc agaagaaggt attacgacat tagacaacgt
    15001 tccgattctt tctgatgtct tcactatgaa tcaagtgatt cgtcacttaa acgtagatgt
    15061 agattttgat gaacaaaaga atcaagtaac aatcgacgct tcaagacaat tagaaatcga
    15121 agcgccttat gagtatgtta gtcaaatgcg tgcttcaatc gttgtgatgg gtccgctact
    15181 tgccagaaat ggacatgcaa aagtagctat gcctggtgga tgtgcgattg gtaaacgacc
    15241 aatcgatttg catttaaaag gatttcaagc tttaggagca aaaattattc aaaaaaacgg
    15301 ctatatcgaa gcaattgcgg atgaattgat cggtaacacg atttatttag atttccctag
    15361 tgtaggtgct actcaaaata tcatgatggc tgccgtaaaa gcaaaaggaa caaccatcat
    15421 tgaaaacgta gctcgcgaac cagaaatcgt tgatttagca aacattttga ataaaatggg
    15481 cgctcaagtc tatggagctg gtactgaaac aatgcgtatt gaaggcgtgg atcatttaca
    15541 tgcagtcaac cactcaatcg tacaagatcg tatcgaagca ggtaccttta tggttgctgc
    15601 tgcaatgaca caaggcaatg tgctgattgc agatgctatc tctgaacata accgcccatt
    15661 gatttctaaa ttgatcgaaa tgggtgcaga aatcattgaa gaagaaggcg gagtccgtgt
    15721 catcggacca aaacatatct tacctacaga tgtaaaaacg atgcctcatc ctggtttccc
    15781 tacagatatg caagctcaaa tgacagctat ccaattagtt gcagaaggta caagtgtggt
    15841 gactgaaaca gtgtttgaaa atcgtttcca acatttagaa gagatgcgcc gtatgaacgc
    15901 tcatgtcaaa atcgacggaa atgtagcaat catggatgga aaccatgaat tgcaaggtgc
    15961 agaagtatat gcaacagact tgcgggcagc agcagcatta gttttagctg gcttgaaagc
    16021 aaatggaatc acacgtgtgc gtaacttgaa ttatctagac cgtggatatt ataatttcca
    16081 tatcaaacta cagcaattag gtgcagacgt cgaacgtgta gacatggatc aaacttctgc
    16141 tgaaaaaaca gcacaaacga ttgcttaagg aagtggctga atgagtaacc aacgatatat
    16201 cttattaact ttgataaaga ttttagtggt gatcttattg cttatccttc tttttgtggc
    16261 cggaacgatg atcggatatg gtgtcatcgg tggcggcaat ccatttaaag tattccagcc
    16321 aagtttgtgg attcatattc gagacttttt tcattgataa ataagaatca cagtggttct
    16381 agtcgatatg aagtgagcca tgaagcagaa catgataaaa gaaaacagaa gggaacgttg
    16441 acgttagtcg cgatcccttt ttttagtaaa agaaaagaag gaatctaatt gatgaagaag
    16501 atattgattt atttagttag aggatatcag cgctttattt cgcctgcatt tccacctagc
    16561 tgccgttatt acccaacctg ttccaattat atgataaaag caattcaaac ccatggtgcg
    16621 ctaaaaggga cggtaatggg gactgcacgg atcttacgct gtcatccttt tgtcaaaggc
    16681 ggtatcgatt atgtaccatt gacattccga ttaacgcgaa ataagaaaga taaaaaagaa
    16741 ccagattata aaaaggttgt gaaaaatacg ggtagcactg agcgataaag aaaaagagga
    16801 aatttattgt caaagtaaca actccgcaac tacttatatg ggggacaaaa aatgatcgaa
    16861 gaactaaaca agaaagattt accatggtcc ttgttattag atgcagatcc tgataaagaa
    16921 aaagttcaag tatatgtttc cagagggagt ggctggatat ggaaagaaaa agaaaaaaca
    16981 ataggtgtac tgatctatgt ggcaagggaa aaagaatacg aaatcgtcaa tgtagcagta
    17041 accccaacgt atcaaggaaa ggggattggc ggaaaattac ttgagacagc ttttcagaag
    17101 ctttcacagc tagcttcaaa ccaaactcgg atcattatac gtactggcac tactagtagc
    17161 gctgcgttac acctctatca aaaaatgggc tatgtggaga ttggtcgagt caaagactat
    17221 tttatccatc attactctga gcccattttt gaaaatggag atcaattaag ggatcaagtg
    17281 attttagcaa ttcacttacc taaaaatagc tttaactaat aaactttcaa ttcgagaaaa
    17341 tgctttcaaa tgctaaatag atacattaca atagctttag caaacaaaaa ggagaatatt
    17401 tttatgggaa tattagtttt tgattttggt ggatcggctg tcaaatatgg ttgttgggat
    17461 ggcaaagaga ttaaaggtaa gggacaattt gcaacgcctg aatcttggga agaaatgaaa
    17521 acgcaattat ttcaagttta taaaaaaata ctcgtttctt ttgaagtcga aggaattgga
    17581 atcagctctc ctggagtagt gaataatgag aaacaggtga ttgagggaat cagtgcgatt
    17641 ccttatattc atggatttaa tattttccga gatttggaaa ctctgtttca actcccagta
    17701 acgattgaaa atgacgccaa ctgtgccgga atggctgaat tttatgaagg tgctgcccgt
    17761 gattatcaag atgttgcttt tgttgtggca ggaactggga ttggcggggc gttgttcacg
    17821 aaaggacaaa taaataaagg ggcacatctt tacggtggag aatttgggtt gatgttctta
    17881 gatggcgata agacattcag taaacttggt acagcggtac agatggcttg gcgttattgt
    17941 gaacgcaaag gtctcgataa aaatgcttat accggaaaag atgtctttga attagcagaa
    18001 actggagatg caatagcaaa agaagaagtt gagagttttt atacgtatct tacaaaggga
    18061 ttattcagta ttcaattttc gtttgatcca gaagtgatcg tattaggcgg cggggtttct
    18121 gcaaaagaag ggctcattga tgagatcaaa agccgaatga agaagctgac agaacaattc
    18181 gatctgcatg atttcgaacc gcagatttta ttatgtgagt acagaaacga tgctaatctt
    18241 ataggtgcag cagcaaacta tctcgctgta cgtcaaggag agaattaaga gctttagaga
    18301 aggtgcagct tgcataaaag aagagaatga aatgaatagg agatttttac ctaaggaatg
    18361 ttttatttgc tgcagtatga taaaatatct gagaggtgaa aatgatgtca aaaaaaaata
    18421 aagatattga agtgcgtata gaagaagtga aaaaagatat caaaggtaag aattatgaag
    18481 tcactcagtt atttataggg aaaaaaatga ttggtgagat cttagcctat gggccaaaag
    18541 aatatgaaat tttctttggt gaagaagatt ttggaaaaga aaaaagtctt gaaaatgcga
    18601 tagaaacagt gattcgacac tggaatctgc acgaataaaa aaatatcaaa aaaactttca
    18661 ataaagggtt gcaaaaatct ggaaaattag gtattataac taagtcaggt tgatacaaac
    18721 ctttcggagg agtagcgaag tggctaaacg cgacggactg taaatccgtt ccttagggtt
    18781 cagtggttcg aatccactct cctccatttc attggggtat agccaagcgg taaggcaagg
    18841 gactttgact ccctcatgcg ttggttcgaa tccagctacc ccagtatacc acaatcgtaa
    18901 gctctcgtta gttcgagagc tctttttttt tgctttgcta ccttgttcct tgaagattct
    18961 gctgaattaa gatagagtta agttaactac aagaattgga gggatccaca tgaaatggaa
    19021 agaaaaagta gacgaagcag ctgaaaagtt atatgatttg gtcaaatcag aaaaatacaa
    19081 tattgaagtg aatattccga aaaaaggcgg aaaagcggtc caggtaaaat caaaacgccc
    19141 aacgaatcat acaaaaaaat ggatggctaa aaaccgctaa taataacaaa agatccataa
    19201 gtcggcattt tcatcgattt tagggtcttt tgttattttc taggttgaac atatctaaaa
    19261 aattgtttct gacaatagga gtagggagaa cgatgtgtgt ctaaatcctc tgttgatgga
    19321 tagaaacctt tatctttttc agttgtgaat caggtatata ccagttataa tagaagaaac
    19381 gaaaggacgg gtgtacgtta tgtcgaatca attacctgta tatatacaga ttcatgacca
    19441 attaaaaaat gaaatcgaac aaggtatatg gaaagtcgga gaccgtcttc cttcagaaag
    19501 agaattagca gtgaaattca atgtcagccg tatgacgttg agacaagcaa ttcaaaactt
    19561 ggcagatgaa ggaatcttag aaagaaagat cggttcgggt acgtatgttg cgcgagaaaa
    19621 agtacaagaa aaaatgtctg gtgcaacaag ttttacagaa attatggaat cacaaaatcg
    19681 agtaccgtct agtcggacaa tctcttattt cttgacttcg ccaagctcaa gtgaaatgga
    19741 aaaactaaac ttgagtaaag atgacacgat cttgcgaatg gaacgtattc gtttcgcaga
    19801 tgatgtccct atttgttttg aagttgccag tgttccacaa aagctgatcg atggctacag
    19861 caaagcagag attactgaat cgttgtatcg cacgctagaa gaaaaaggcg ggaaaaagat
    19921 cggtccagcg aatcaaacga ttactgctgt gttggcttct gagaaaattg ctgactattt
    19981 agaggtaaaa cgaagagatg cagttcttcg tttgcgccag atttcttatt ttgaagacgg
    20041 tacgccgttt gagtatgtgc gtacgcaata cgtaggaaat cgttttgagt tttatttgga
    20101 aaaataaaaa acaggtgatc cctgattcct tattagaaat aaaagagaat cagaatcacc
    20161 tgtttttata tatgatcagt tatcagttgc tcgtgataag aaacagaacc ctcttcaaat
    20221 tggacttgtc cgttcagcag ctcaatgatg gattctttaa agtggttagc acttttttca
    20281 tctacagcac agatgacgct aacttgatca gtatattgga tttcttttat aaaaaaatgt
    20341 tggagttcaa gataattctg taattttcct agttgcggat acgtgatcat cacagagatc
    20401 tcctgttgca aggtaccttc tacgattcca atgtcagaca atgcttgaga gaccgcatga
    20461 gtgtatgctc gtattaatcc gcctgtgccg agtttcgttc ctccaaaata tcgagtgact
    20521 actgcagcta cattgatcag ttgatttttt ttgaggactt ccaacatcgg tacgcccgcc
    20581 gttccacttg gttctccatc atcgctgctt cgctggattt catttttttc tccaatgatg
    20641 aaggcgctgc agttatggtt cgctttccaa tgttcttttt ttatttcttg aatgaaattt
    20701 tttgcttggt cctctgattc tattcgtcta agagaacaga taaagcgtga ttttttgatc
    20761 tcaatctcac tttgtccatt ttcttttatt gtacgatagc gctcgatcat cttgtcacct
    20821 ctttttttca ttttctttat tcagtataaa taaagttcta ggttgtttca acactgtaac
    20881 ggttgcgcaa ttgctgtagt atgcgataat aaagacaaag gcaggtggat ctggggatgc
    20941 aggaacgaat gaaaaagtac gatgcaatta cgcattattt gaagaacaat ggcggctctc
    21001 aagtaacgtt gacctttacc caatttgacg aactgctgtt tcccagtaac ggacttccca
    21061 aaacagcaag ggaaagtaca gattggtggg caaatgatta taaacaccct gaaaaaggtg
    21121 cctatggctg gataaatgca ggctatgaag tagttgtcat caatttggac aaagaatatg
    21181 tcgtgttcaa taaattagtg aaatctagtt ggctatttga ttaaataaac cgcgtttaga
    21241 aaacgttgac aaatttcttt ctttttatat aataaagtaa cagacgcgaa gaaaacgttt
    21301 gcgtagtttg ttttaaaaag gagagaaaaa tatggctaaa aaaacaatca tgcttgtatg
    21361 ttcggctggt atgagcacaa gtttactagt aacaaaaatg caaaaagctg ctgaagcaaa
    21421 aggaatcgac tctgatattt tcgctgtgtc cgcttctgac gcagataaca atcttgcaaa
    21481 taaagacgtg gatgtgttgt tattaggccc acaagttcgc tttatgaaag ctgattttga
    21541 gaaacgtctg gaaccaaaag gcattccttt agatgtcatc aatatggctg attatggtat
    21601 gatgaatggc gaaaaagtgt tagatcaagc aatcgcgctc ataggtgaat aaatagaaca
    21661 gtataactat cgaacaagcg atccaaaaaa tagatcgctt gttttttcgt atattttttt
    21721 agggcgaata atatgaatca tttttggggt agaaggcttc tgacgagaga tattaaagca
    21781 atagactgtg aggaggtaaa tttaccaaat tatgagaaga tcgcagcagt ggaacgtttg
    21841 ggcaactgga ttctttgtca tcgctgtgga atgaggacgt ccgtcattgt tggacagctt
    21901 gcagattacg gttatttttg tacacattgt ctatatttag ggtgatgcga cactcaacaa
    21961 gatttatatt tgtttgatca gcctgaagca aaacctcgag aagtcgtctt tttttggaca
    22021 ggacagctta ctgaaaaaca aacggaaatc gcaaagagaa tactttgcca ttcagaaaaa
    22081 agacatcatc ttatttgggc tgtaacaggt gcagggaaaa cagagatgct ttatcctatt
    22141 ttagtggaaa ctttaaaagc tggaggaaga gtagcgattt gtacaccgcg agtcgatgtt
    22201 tgtaatgaat tgtttttacg ctatcgttat gtttttccag aagaaaaaat cacgttgctc
    22261 catgggaata cagcaacggc ttataccttt acttcttttg ttatctgtac gattcatcag
    22321 ctataccgtt tttatcggtc ctttgattta atagtgatcg atgagatcga tgcgtttcct
    22381 tataacgggg atgctgggct agctcacgct gtgcaaacag caatcagatc aaacggccga
    22441 ttcatctact taagtgccac gcctgatgag aagttactaa aggaaatcaa gcagacattt
    22501 gagctccaca aacttgcctt gcgctttcat cggcgcttgc ttcctgaacc cgtgcttgtt
    22561 ttcatgaata attggcgaca aaaatgtgga aacaaaaaga aaatcaactc tttggtgcgg
    22621 atcattcagc aactaatcaa agaaaaccgt atccttttat tttgtccaag tattacgatg
    22681 atgcatcgtt taaaaatcac actgcaagaa gcttttccag aatatgagat aacagatgtt
    22741 tcttcacaag acgatcaacg ggcaaagaaa gttcagaaaa tgcgagaagc aatatacgag
    22801 atactgttaa ccacaatgat cctagaaaga ggagtcacat ttgaaagaat ctctgtcatc
    22861 gttttaggag cagatcatcc agtttttact aaatcctctt tggtgcaaat cgcaggaaga
    22921 gctgatcgta aaggtcctta tacgaacagt cgagtctatt ttttctatga agaaaaaact
    22981 tcagctattc gaaaagcctg tcaggaaatc aaagaaatga acgaagaagg gaagcagatg
    23041 ctgtgagatg tagttgctgc ggtaaagaca tcattcaaaa tttaacattc agcgagatca
    23101 tcggagtgtc gaaatctaga cttcctcaga catgttcagt ttgccgcgca caattccatt
    23161 tattagaagc aaaaggttgt gcaggttgtc aaaaaccaat ccatttgaaa ttcgaggaga
    23221 cgaaaaagaa agcaaatact agtttcgttt actgcaacga ctgtcaagaa tggaagaaga
    23281 aatatcctgc atatgatttt caacaccgcg ccttttttac gtacgatgaa aagatgcagg
    23341 cttggatcaa tcggtacaag tttatgggag atatccgatt agcagggact tttgcatata
    23401 aatggactca gataaaaaaa agattacccg gcatatattt attgtccaat acctttatct
    23461 gaaaaaaggt ggctagaaag aggattcaat caagtaagcg agatgttgaa agcagcaaaa
    23521 attccttttc agatgctgct caaaagagag caacatctgc ttgctcaagc aaaaaacacg
    23581 cgaaaggaaa gattggagat gcctcagcct tttgagcttg ccgtacctct ttctaagata
    23641 caacataaaa aa
//
LOCUS       DAFLWC010000043        23149 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.044, whole genome shotgun sequence.
ACCESSION   DAFLWC010000043 DAFLWC010000000
VERSION     DAFLWC010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23149
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.044"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(18..596)
                     /locus_tag="L1V17_001569"
     CDS             complement(18..596)
                     /locus_tag="L1V17_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBN1236342.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(673..1203)
                     /locus_tag="L1V17_001570"
     CDS             complement(673..1203)
                     /locus_tag="L1V17_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBN1236343.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(1207..2067)
                     /gene="rlmB"
                     /locus_tag="L1V17_001571"
     CDS             complement(1207..2067)
                     /gene="rlmB"
                     /locus_tag="L1V17_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBN1236344.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(2060..2455)
                     /locus_tag="L1V17_001572"
     CDS             complement(2060..2455)
                     /locus_tag="L1V17_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBN1236345.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(2452..3864)
                     /locus_tag="L1V17_001573"
     CDS             complement(2452..3864)
                     /locus_tag="L1V17_001573"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBN1236346.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(3861..4397)
                     /gene="cysE"
                     /locus_tag="L1V17_001574"
     CDS             complement(3861..4397)
                     /gene="cysE"
                     /locus_tag="L1V17_001574"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBN1236347.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(4483..4722)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(4719..6179)
                     /locus_tag="L1V17_001575"
     CDS             complement(4719..6179)
                     /locus_tag="L1V17_001575"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBN1236348.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(6349..7506)
                     /locus_tag="L1V17_001576"
     CDS             complement(6349..7506)
                     /locus_tag="L1V17_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBN1236349.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(7540..8910)
                     /gene="radA"
                     /locus_tag="L1V17_001577"
     CDS             complement(7540..8910)
                     /gene="radA"
                     /locus_tag="L1V17_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBN1236350.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(8973..9500)
                     /locus_tag="L1V17_001578"
     CDS             complement(8973..9500)
                     /locus_tag="L1V17_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBN1236351.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            9730..10536
                     /gene="proB"
                     /locus_tag="L1V17_001579"
     CDS             9730..10536
                     /gene="proB"
                     /locus_tag="L1V17_001579"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HBN1236352.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            10533..11780
                     /locus_tag="L1V17_001580"
     CDS             10533..11780
                     /locus_tag="L1V17_001580"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HBN1236353.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            11856..12200
                     /locus_tag="L1V17_001581"
     CDS             11856..12200
                     /locus_tag="L1V17_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236354.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(12317..12643)
                     /locus_tag="L1V17_001582"
     CDS             complement(12317..12643)
                     /locus_tag="L1V17_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236355.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(13258..14460)
                     /locus_tag="L1V17_001583"
     CDS             complement(13258..14460)
                     /locus_tag="L1V17_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1236356.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            14577..15092
                     /locus_tag="L1V17_001584"
     CDS             14577..15092
                     /locus_tag="L1V17_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBN1236357.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(15291..15737)
                     /locus_tag="L1V17_001585"
     CDS             complement(15291..15737)
                     /locus_tag="L1V17_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBN1236358.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(15784..17262)
                     /gene="msr(C)"
                     /locus_tag="L1V17_001586"
     CDS             complement(15784..17262)
                     /gene="msr(C)"
                     /locus_tag="L1V17_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBN1236359.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(17616..18245)
                     /locus_tag="L1V17_001587"
     CDS             complement(17616..18245)
                     /locus_tag="L1V17_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBN1236360.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(18229..18693)
                     /locus_tag="L1V17_001588"
     CDS             complement(18229..18693)
                     /locus_tag="L1V17_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1236361.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(19180..20448)
                     /locus_tag="L1V17_001589"
     CDS             complement(19180..20448)
                     /locus_tag="L1V17_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBN1236362.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(20679..21416)
                     /locus_tag="L1V17_001590"
     CDS             complement(20679..21416)
                     /locus_tag="L1V17_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1236363.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(21483..22052)
                     /locus_tag="L1V17_001591"
     CDS             complement(21483..22052)
                     /locus_tag="L1V17_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBN1236364.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            22180..23052
                     /locus_tag="L1V17_001592"
     CDS             22180..23052
                     /locus_tag="L1V17_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1236365.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
BASE COUNT         6499 a         4943 c         4196 g         7511 t
ORIGIN      
        1 attaagattt ttctaaatta ttcctcatta taaaatttca agtgtttttt tattttgagt
       61 tttactctcc cgtaagcgct cattacttgc ttgtgatcca ttgctaaaca ttcagccatg
      121 tctacaaaat caacgccttg catataataa tgaaaaattt tagcttctat ttttgaaaac
      181 tggatttcgc aattttcgat tgcttctttt aataaaagat gctgaattgc taaaggttct
      241 tgcaatgtga tctctgctaa aaagtctggt ccttctgtct ctattttttg gtcgattgag
      301 acttcatctt tttgatcacg acgcttcagc gcgttctgct tcctcaacag agaatagatt
      361 tgattgctta taacgctttt ataataactt ccaaagctaa cacctttgct tttttcgtaa
      421 gttctcaatg cctgatataa agcgatcctt gcttcttgtt cccaatcctc agaaacataa
      481 tttcttaaat aataggtgtt tttcaaacgt agtaaaagtg gaaaatattt ttgatacagg
      541 gcagcaaatg cttcttcgtc accattacgt gcagcgcgca ataactcctc agacataaaa
      601 taattcctcc ataaattcgt ttatggagga atcttatcat caatgattca tcgaactgat
      661 tagaacgata tgttatttat tttttctcat taaatcgtcc aatttttggg acaatttttt
      721 taactgctct tcattccatg gagaattacg tcggaaatca ataaaatgca tatctttatt
      781 ttcttgggct attgtttttt ccgttttttt tatcgtctta tataattcat aagcagaagt
      841 tcgtaatgct ccttgggaaa agatcatcca ctgttctgct aaatcgcttg tcgccactgt
      901 cacttgtgtc aaacggtcat tcagctgacc agcgattctc tcgatataac tgtcagccgt
      961 ttcgtcttct ttcgtaaaaa caacatccaa ctggtatttc ttataatttt gttggatgcc
     1021 cggaactagt tgggcatcga agacaacgat gacttccatt ccttcatatt tcgcataatt
     1081 tgataaacga tgtaaaagag cttctcttgc atccgccatt ttgtcctgct ttttaagctg
     1141 gacaagttcc ggccacgaac caatcatgtt gtagccgtct acaatcaaca gctgtttttt
     1201 catggtctac tccccctgac gttgggaaaa agcctgatac ataagcaaac cagcagcaac
     1261 actggcattt aagctctgga cgtgcccggt catcgggatc gtcagcaatt catccatttc
     1321 ttttttcaat cctggactca ttcctttgcc ttcattacca atgactaaag caattgatcc
     1381 tttggcattc catttttgga agtttgtgcc ggtcatatct gtgccaaata cccaaaatcc
     1441 tgtttctttg agctgttgca cagcttgtac caaattcgtc acgcgtgcaa cagggacatg
     1501 ttcgactgcc ccagtggaag tctttgttac gataggtgtg attccaactg ctcggtgttt
     1561 tggtatgatc acaccatcga cgccacttgc gtctgctgtc cgtaaaatcg acccaaaatt
     1621 gtgtggatct tcgatgctat ccaaaatcaa aaagaagggg tcttcttttt tctcttttgt
     1681 tcgttcaatc agttggtcaa gggataaata ttcataaggt gtaatcgcaa gaacgactcc
     1741 ttgatgcacg ccgtgatcgc tcaaagtttc taatttttgt ttaggaaccc atttgactgg
     1801 cacagcttgt tcacgtgcga tttctttcag ttcttctact ttttctcctc gtgaatcttc
     1861 ttgaagaaag agtttattcc ctcgcccttg ttgtagcgct tctactgcgg catggtgccc
     1921 aaagacgaaa ttatcttcta atgcttcttc attttgatca gaaactgact gatttcgtcc
     1981 agtttgcttt ttatttgaat atctattttg ttttttgtct tcaaatccac gtttcgattg
     2041 atgtttgttt gttctttctt tacccatttt tttcaccaac tttctgaata caccagcgga
     2101 tcaattcttc catccgctcg gtttgttttg tcaaatgcag atagcccatg agcgcttcga
     2161 accctgttgc gacccgatac gtcgtaacat cagcattttt tgcgctcgta tggcttttag
     2221 catttcttcc tctgcgataa taaagttctt cttcttctgt caaaagatgt tcttccagca
     2281 tttgctgaat caaaaaggct tgtgcattcg cagaaacata attcgttgcc gcacgatgca
     2341 gcttattggg ttttgtttct ccttgatcaa tcaggtggtc acgaacatag atttcgtaaa
     2401 tcgcatctcc aacataagcc aaggctaaac cgttcaattg tgtgtaatct ctcatgcttc
     2461 tcttctccat cgggttcctt gcggtgtatc ttctaataag atcccttttt ctttcaacaa
     2521 atcacgaatt tcgtcgcttc ggacaaaatc acgattgctt cttgcttgat ttcgttcttc
     2581 gatcaattgt tcaatctctt catctaataa ctcttctgct gtaaataaaa taccgaagat
     2641 cgaaagccat tgcgagaata aagcttctcc ttgtgccaag acagcggcag aaactttcgg
     2701 ctggtctaga taagtgttca gccacttagc aagctcatag accactgtga tcccatttgc
     2761 tgcattaaaa tcatcgtcca tttcttcgat gaatcgctgt tctaaatttt ctaacaaagc
     2821 gattttatcc gcatcatctg ccaaattctc tgaggcagtt tcttggcgga atttcaaatt
     2881 gtcaaacgta ttcttcagtc gttgtaaatt ggtggctgct tctttcatcg tcgtttcact
     2941 gtagcggatc ggacgacggt attgtgtggt cgccatgaag aaacgcaaga cttgtggatc
     3001 aacgtttttg atcatttcat gtacagtgat gaaattccct agagatttac tcattttttc
     3061 atcgtcttcg ccaatcgtta catagccatt gtgcatccag taattagcga attttttccc
     3121 tgttttcgct tcactttgtg cgatttcatt ttcatgatga ggaaattcta aatcttgccc
     3181 gccaccatgg atatcgatcg tttctcctaa atgttttgtt gccataacgg aacattcaat
     3241 atgccaaccg ggacgtcctt tgccccatgg tgaatcccaa gaaatctcgc caggttttgc
     3301 ttgtttccat aaagcgaaat ctaatgggtc ttctttttgc tgctgttctt cccctgtacg
     3361 ctgacttgct ccgacttcca gttcatcgat ggattggtca cttaatttcc cataattttc
     3421 aaatttacgg gtacggtaat acacatcacc tgaagattca taagcatagc ctttttcaac
     3481 caacacttga ataaatgcta aaatatctgg catatgatcc atgactcttg gatgcagtgt
     3541 agcaggttcg acattcaacg ctttcgtatc ttcttcaaat gctcggatga aacgatcagc
     3601 aacttctggt gctgtaatac ctaattcgtt tgctgtacgg atgattttat cgtctacatc
     3661 cgtgaaattc gatacgaaat cgactttata gcctcgatat tcaaaatagc gtcgaattgt
     3721 atcgaaagca atggtgctac gagcatttcc gatatggata taattataca cagtcggtcc
     3781 gcagacatac ataccgacat gtcccttttg tatagggatg aattcttctt tttttctggt
     3841 caatgtattg tagattttta tcattctgat ctcctcactt tttctccttt gattcgaacg
     3901 acttttgctg gtactcctac cgctgtagcg tcgtctggaa catctttcaa cacaacggca
     3961 cctgcaccga ttttggcgtt ttttccgatc gttaccggtc ctaatatctg cgcattcgca
     4021 gagagcatgg ctccttgttt aacagttggg tgtcttttac ccgtttcttt tcctgtgccg
     4081 cctaatgtta cgccatggaa taaaatcaca tcgtcctcga tttctgcggt ttcgccaatg
     4141 acgattccca ttccatggtc gatgaacacg ccagttccaa tcgttgctcc tggatggatc
     4201 tcaacaccag ttaggaaacg ccagaattga gcattgatct tcgccaataa aaagagccgg
     4261 tgctgatata aaaaatgaga gaaacgatgc caaaacaagg catgaaaacc agggtatgtc
     4321 aaaacgatct cagctgtcga acgtgcagcc ggatcgtttc tctttgctgc atcaatcgct
     4381 cgggtaaacc aactcatgac tttccactcc tttcgtaaga attttatgta ggaaatcatc
     4441 ttcttataaa gaaaagaagc gccttttaaa taagtttcct tatcaaaaga cgctttccgc
     4501 gtggttccac ttttcttcat aatcaatgat tatctctgac agctaacgcc tgttatacgt
     4561 tcttggctac tttgtttcct ataaaacagt ttttcctgtt ttctgtgttt cgccaagacc
     4621 actcccagag gcatttcggc aaccattcat tgataccttg caccacccgg tatctctctt
     4681 gtaatgatca gctgcttact tttttctgtt catcgtgttt agttcagtac ttgatttaaa
     4741 tgtgctaatg atttttcacg accaagcaat tcgatcgttt caggcaattc tggaccatgc
     4801 atttgtcctg atacagctac acggattggc atgaaaagat tttttccttt tacgccagtt
     4861 tctttttgaa cagctttgat ggcagctttg acagttggag catctactac ttccatttgt
     4921 tctagctgtg ctttgaatgc gtggagaaca gtaggaactg tttcaccagc aagtacttct
     4981 tttgctgctt cattcaatac aggatgttca ttgaaaaata gcgtagacag atcaacgatt
     5041 tctgcagcat agctcatttg aggttgatac aggctaacga tcttcttcac ccattcgatt
     5101 gtcttttcat ctgggttttc tgctacacgt ccatcagcga ttagataagg cagacacatg
     5161 tcagtaaatg catctagatc cattgctttg atgtaatggt tgtttaccca ttgcagtttt
     5221 ttcgcatcga aagctgcggg tgatttactt aggcgttttg gatcgaacat tttgatcaat
     5281 tcttggtgtt cgaagatttc gtcttcgccc acaggtgacc agcccaataa tgcaataaag
     5341 ttgaacattg catctggtag atagcctaat tcgcgatatt gttcgataaa ttgcaagatt
     5401 gattcgtcac gtttgcttag ttttttacct gtttcactgt tgatgatcaa tgtcatatgt
     5461 ccgaaggttg gtggtgtcca gccaaatgct tcatagatca tcagttgttt tggtgtattg
     5521 gcaatatggt catctccacg taaaacgtga gtgattttca tcaaatgatc atcgaccgca
     5581 acagcaaaat tataagttgg cataccatcg cgtttttgga tgacaaagtc gccaccgata
     5641 ttatcggatt cgaacgaaat agcgcctttc accatatctg taaatgcgta ttctgtattg
     5701 cgaggcacac ggaaacgtac aacagattct agaccttgtg cttctttttc tgcttgttct
     5761 tcaggtgtca agttcgcaca tgttcctgcg taatgaggca tttctcctct tgcgcgttgt
     5821 gcttcccgtt ctgcttctaa ttcttcttct gtgcaatagc atttgtatgc tcgattgcta
     5881 gcaagcagct gatcaatcag cggttgatag atttctttac gttcagattg acggtaaggg
     5941 ccgtattctc caggattttc aggagattca tcccaattca ttcccaacca agcaaggttt
     6001 tccaactggc ttttttcgcc atcttcgata ttacgttttt ggtcagtatc ctcaatacga
     6061 ataataaagt ctccatcatt gtggcgggca aacaaataat tgaataatgc agttcttgca
     6121 tttccaatat gcaggtgccc agttggactt ggtgcatagc gtacgcgtac tttcgtcatt
     6181 ttcttcctct tctttcaaac tagactttga ctaacagcaa aaattccgtc agttacggct
     6241 tctcaaatat catttattta aagccactca gcacaaattt taccttttct aaggtaaata
     6301 gtaaagccaa ctggttgaat ttccttacca gttggctgaa tttctttttt attttgattg
     6361 tttagtcttt ttctctgtct cttttttatt gtcgattcct cgtcctgcat gtgcaggttt
     6421 agcaaagatc atgcgtccag cagctgtttg aagggcactt gttacaacga cttcgatacg
     6481 ttcattcatg taatgctgtc catcttctac gacaaccatc gtgccgtcat caaggtaggc
     6541 tactccttgt tggcgttctg tcccggcttt tactactaga acattcatcg tttcaccagg
     6601 gatgacgact ggttttacgg catttgccaa cgcattgata ttaagaacag gtacattttg
     6661 gaattcagag actttattca agttatagtc attggttaca atgacaccat ctaaaagctt
     6721 agccaatttg atcaatttgc tgtctacttc actgatatct tcaaagtctc catcgtacat
     6781 ttcgacagat ataccctctt ctttttgcaa ggcatttagg atatctaatc cgcgacgacc
     6841 acgcacacgt ttcaaactat cccctgagtc cgcgatgtat tgtagttcgt aaagaacaaa
     6901 attagggatc atcaaggttc cttctaagaa tccagtcttt gtaatatcat aaatccgacc
     6961 gtcaatgatc acgcttgtat ccaagatttt atatttatgg aaattttctc ctgattttcg
     7021 ttctaacagt tgactctcaa cttgactagc tgtttcttgc tcgatttttt tgcttcgtga
     7081 accaaaaact ttcttccatt cttcgattcg tgtcgttccc attctcaatc ccagatagcc
     7141 taagatgatc atcagtaaaa tcggcaatac actattgacg aatggaattt ccatattgta
     7201 aagaggggtc gagatcacaa cacctaaagt caatccgatg atcgcaccga tcgcaccgaa
     7261 gagaagataa gtcaagctga cctcacttag tttttgttct acttgtttga taatagctga
     7321 gatatgtttg gccaacagca aagataataa aaagaaaata agtgcgccta acaggctgtt
     7381 ggtaaatgta ttattcagcc atccgtttga ctgttgaccg attgcctgcc aagctgaggg
     7441 taaaaatgaa atacccaagc ttgcgccgac aatgatcatc agcaaagtaa tgacacgttt
     7501 ttgcatcgtt tttcctccgt ttcgacaatc atttattagt tagcggaaca cacgcttcaa
     7561 cgtttcagcc aaagttgcta ctccaactat ctcgattcct tttggcgctt cccagttacc
     7621 taagttgttt ttaggtaggt atacttttgt gaagccgagt ttttggactt ctttgactcg
     7681 ttgttcaata tgactgacac gtctgatttc tccagtcagt ccaatttcac cgatgaaaca
     7741 ttccgttggc tgtgttcctt tttctttata gcttgaagca atactgacag cgatagctaa
     7801 atcaatcgct ggttcattta attttacccc acctgcagct tttaagtaag catcttgatt
     7861 ctgaagaagc aacccagctc ttttttccag cactgccatg atcagagata cccgattgaa
     7921 atcaagacct gttgttgttc gtttggcatt tccgaacata gtaggtgtga ctaatgcttg
     7981 gatctctacc aaaattggac gtgtcccttc cattgccaca acgatagcag agccagttgc
     8041 accgtctagg cgttcttcta agaaaatctg tgaaggatta gcgacttctt ccaatccatg
     8101 ctcatgcatt tcaaaaatcc caatctcatt cgttgagcca aatcggtttt ttactgctcg
     8161 caaaatccga aaactatgat gttgttcacc ttcaaaatat aacaccgtat ccaccatatg
     8221 ttctaacatt cttgggccgg cgatcgagcc ttctttggta acatgaccga cgataaaaat
     8281 ggctatccca tttgttttag cggttttgag tagttctgca gtggtttctc ttacttggct
     8341 gacacttcct gccacacttg tgatgtctgg ctgcgtcatc gtttggatgg aatcaatgat
     8401 aacataatca ggggagatat gttcgatggc acgactgatt tcgttcatat ctgtttcagc
     8461 gtatagataa aattctgtgt tgatacttcc gaggcgttcc gcgcgtaatt ttatctgctc
     8521 tgcgctttct tcgccggata catataagac ttttccgcct atggctgcta attgctgaga
     8581 aacttgtaac agcaaagtgg atttcccgat acctggatcg ccaccaatca agaccataga
     8641 ccctggcacc acacctccgc ctaacacacg gttcagttct tctaattttg ttttgatccg
     8701 aggttctttt ttagggacga cgtctgcgat ttttgttggt tttgcttttt ctcctgtcaa
     8761 acttgtccga gttctgcggt ccgttgtatc ttgttcgatt tcttcgacca tcgtattcca
     8821 ttttccgcaa tttgggcagc gtcccaagaa cttaggcgac acatacccgc aattttggca
     8881 aacaaattgt acttttgatt tttttgccat tgtaccgcct ccttttatcc taatcatgag
     8941 acattaaatc aagcttaagt atctttaacg ttttatttac tggaagaacc aaatccgcct
     9001 tgacgttgag cagtcgtttg atcttgatct gcttttaaaa acggcaaaaa gatcccttgg
     9061 ccgatacgct cgcctttttt gatcactaca tccttgaaac caaagttggt gaattggaac
     9121 atgatatggc cttcatttgc ctcattattg taataatcac tgtcaatcac acctactccg
     9181 tttgtcaaca ctaaaaaccg cttcaacgga ttgcttgaac ggttagcaag ctgcaaaaat
     9241 tcatcttctc ccatgtaagc tttgattcca gtaggcacga gggttggttt caattgtttt
     9301 tcattttctg atacatcttt tttcaatcca tctgcgactg tttccaaccc ctttttccag
     9361 cctgctttcc agatacttgg aatcacgacc tcttctgctg cttcaaaatc atagccagca
     9421 gcatgatgtg tagcgcgctg cggtagattg atattttgat ctttatattt agaaataact
     9481 tcaaatcctc tttttctcac cggttttcct ccctaaataa actactccta ttctaacata
     9541 tccgaggctg taaaagactt tctttacaaa ttcttcaaga aattctgcta tcttaaagta
     9601 aaccattaat tcgttctttt tccaaacgac tgcaagttgt acaaaaaaac tattttttac
     9661 atgactttac tcgtcaaaac aagtagaata gaacgaaatt aatgagtgga tatttgattg
     9721 aggtgtcaca tgcgtaaaga aattaaaaat gcaaaacgaa ttattgtcaa agtaggaaca
     9781 agtacattga tttatcccaa tggaaatatc aatcttgcgg caatcgatca gttagctttt
     9841 gtcctttctg atcttagaaa tcggggaaag gaagtgatct tagtctcatc aggagctgta
     9901 ggcgttggta tgcataaatt acatttgtca gaacgtccga ctttgattcc tgaacagcaa
     9961 gctgcggcgg ctgttggtca agccgaactg atgaatatct ataatcaaag attcagtgta
    10021 tataatcaac agacggcaca gatcctcgtg acaagagacg tggtagatta tcctgaaagt
    10081 cgtaaaaatg tgaggaatac attggaacag cttttgatta tggacacgat ccctatcgtg
    10141 aacgaaaacg atactgtagc agtggatgaa ttagatcatc tgacaaaatt tggcgataat
    10201 gatcagctgt cagccatcat ggcaaaactt gtcgcggcag accttttgat cgtcctttct
    10261 gatatcgacg ggttttattc agataatccg actacaaatc ccgaggctca gatgtatcgc
    10321 tatatcgata aaatcgatga aaagattctg gcacaagcag gtggtgctgg tagcacattt
    10381 ggaacaggcg gtatgcagag taaattaaaa gccgcttcta ggatatttga agcaaacagc
    10441 gcaatgattt tagcaaatgg aaaaaatccg gcaattattt ttgatattct tgcaggaaaa
    10501 gaagtaggta ctttatttaa ggaggacttg aaatgactga cttgatgcaa ttaggacaac
    10561 aggcaaaaga tagcgcgcaa caactagcac ttatgcctac aaaccgcaaa aatgagctac
    10621 ttgttcaaat ggcacaaacc atcaaaaaga atcaacaagc gatcattgaa gcaaatcata
    10681 aagacttaga aaaagcagtc gaaaacaata tcagtgaaac gatgcaagac cgcttgcagc
    10741 tgacacctga gcgaatcaat gccatggcta cagagatcga aaaaattgct tcgttagacg
    10801 atcctattgg aaaagtagat gagatgtgga cgaacaccga cggattgaga atcggcaaaa
    10861 agcgcgtgcc actaggcgtg atcggcatca tttacgaatc tcgtccaaat gtcacgacag
    10921 atgcagctag tctagcattc aaatcaggga atgccgttat ccttcgcggt ggcaaagaag
    10981 cattcttctc gaatcaatta ttagtccaat tattgcagca agtactggtc agtgctggcg
    11041 aatctcctta tgccatccag tttgtcgatg atacttctca tgaaactgca ggacagttga
    11101 tgcgattgac agaatactta gatgtgctga ttcctcgagg cggagcaaaa ttaatccaac
    11161 gagtcaaaga acaggcaacg gtacctatca ttgaaacagg tacaggaaat aatcacgtat
    11221 atatcgataa agaagcacag ttatctatgg cagtgaacat catcgtcaat gcaaaagctt
    11281 cccgtccatc tgtctgtaac gcggcagaaa cattgctgat ccattctgag atcgcacctt
    11341 ttttcttgcc agctattgaa aaagaactgg tagaacacgg ggtctcttta cgtgcggatg
    11401 ctcgtgcgtt agaatatcta gagacggctg ctttagcaga agacacagat tgggatactg
    11461 aatatctaga ttatatcctt gctgtcaaag tggtcgattc tttggatgaa gcaattgcac
    11521 atatcaatcg gcataatact aaacattcag aaacgatcgt gacagatagt tatgcggcta
    11581 gtcaacgttt cttaaatgaa gtggacgcgg cggctgtcta tgtcaatgcc tccactcgtt
    11641 ttacagacgg atcggtattt ggttttggtg cagagattgg tatctctact caaaagttgc
    11701 atgcccgtgg tccaatgggg ttaaatgaat taacttccac aaaatatatc atttatggcg
    11761 atggacaaat ccgcgaataa tgtttcgtgt gaaacattat tcccgccttt tgcctttttt
    11821 ctgtaaaggt tctatccaac tagaaaggtg tcaatatgtt tgaaatttta atgatttttt
    11881 ttatttacct tatttctctg aatatcgctg cttttctggg agtcggtatt ttatcccttt
    11941 tctttcaatt caaaaaacga agcataggga gtcaacggga aaaatggtcg cagtattttg
    12001 acaaaatcgg gcaaaaaggg ctggttacac gcttgcacat tagttacatg gttgcattat
    12061 gcttattagc gacaatcaat tactattctt ttttcgatca ttcaatcgct tatacgatta
    12121 cgctactgat tgctgggatt tttcacttat cttataaata tcagctgaat aaaaaccact
    12181 tgaatcggac tttccgctaa aaaatatccg tacgataagt agagtgcctt gaagatcggc
    12241 aaaaaactgc cggacttttt agaggctgtg acaaagattt tgtcacagcc tctttttcca
    12301 tataaacggc gttcgcctac cagctgcctg gtaaatctgt ttcctcttcg ttaagaagcg
    12361 aaaatccgtc aaatgtttcg ccatcataat aacgaagcag ctcatccatg gacaagttca
    12421 tcgttttttc tttttcttct tccgctgatt cagccagtag ctgttcccga tacacctgat
    12481 acataccagc tattttttgc tgcatcgctt ttctagtttc accttccgca ttgattattg
    12541 gcaattcttt gatatagcca cgataaatca accgatcatc tgaaaattca atgggtaatt
    12601 caacgagtgt caacccgact tcctgaaaat attcttccag catctattat ccccccattc
    12661 tttttcttaa atgaatttta gcttacctac tgaaaatttt ccagtttcat tattttgaga
    12721 aaaaaaggga atgtgacaaa aatcgtgtca catccccttt ttccgaataa atggtgttct
    12781 tctgccaact cctcaatcat aagtcacaat attcaacaaa catgagaaac tgttttttga
    12841 aattgttcct tgtgattcag agttaaacga cagtctcaca acctcttggt aaacggcgtt
    12901 caatcagctg accctcggta ttagctcaaa aaacggtaaa atatgagaag ctatttttcc
    12961 gttttgtttc tctaatactt aggataaaac gctgatttta caacctctgt taaacggtgt
    13021 tcaatcagct gtccttcggt attagctcaa aaaacggcaa aatatgagga actatttttc
    13081 cgtttgtttc tctaatactc aggacaaaac gctgatttta caacctcctg ataaacggtg
    13141 ttcaaaagct tgcatctgcg gtaataagcc caaccaaacg aaaaatatga gaagctattt
    13201 ttgtttggct gttcttatga cttgatgcag gacagctttt tcacaacctc tgatttctta
    13261 ttcttcttca tttgtagcaa aataattacg gtgataaatg atacaacata cactgataag
    13321 aacaatggca cctgcaaaat aaaacgcata gctttcacca atatgttcac caatcacacc
    13381 tgcaataaat ggtgctaaag ctccaccgaa aaagcggaca aaactatagc tggacgaagc
    13441 aacgtttcgt tgcagacctg gtatttccat agcaatcgtc gtcaacagtg tattgataat
    13501 tccttggaaa aatcctgcta acacaatgct gatcggtaca aggactggca tagaagttcc
    13561 agctcctaat aacagcaaac aaataatgaa taagacaaat gctgctaaaa ttgtccgata
    13621 agtcgtaaac ttccgctcaa gagccggtgc aacgaaaatc gaagcaatag ccagaagcac
    13681 accccagcca aaaaatacaa aaccgacttc taattcagaa tagccaatca ataaaaatgg
    13741 cgcatacgca agtaaagtaa agaatccgaa attatataac aatgcgatta gtccaactga
    13801 acgaagttta tgattgctta acgctttgac accttcccaa aggcctactt ttctctttgg
    13861 tttctcagtt tcaggtaaaa gtaccgctag ggctataaaa ccgcaaaaca tcaaaaatgc
    13921 taccccaaaa aatggataac gccatgaacc actgcccaag accccaccga ctagagggcc
    13981 aacagccatt ccgcagccaa gtgctgcttc atacatcatg attgcttttt ctgtgttacc
    14041 aactaaaata ctgacgatcg ttgctaaagc agtagagaca aataaagcat tcccgacacc
    14101 ccagccggca cgtaacccaa tcagcattcc gatattccca gataatccgc caagaccagc
    14161 gaatacaacg atgataaaca atcctgtcat caatgttttt ttcaaaccga tccgactaga
    14221 taagaaacct gtaaatagca tcaccacacc agtgactaac atgtaactag taaataacag
    14281 ggtcgtttca gctggcgtag cgtttaactg tgcagcaatc gtttttaaga ttgggtctac
    14341 tagacccact cccataaaag cgatcataca ggtagctgct acaactagcg ctgaactttt
    14401 cccctttgtt tcttcatttg tttgttcttg tatatctatt tgattctcca atatttccat
    14461 ccctttctct ctattagcat catacatgat ttattttaca tgtcaatatg cacatgtaaa
    14521 acgtggaaac tttactgtga tataataaag aaaataagac gagaggtagg atttttatga
    14581 atactttagc ctatatatta ttatgcgtgc ttttatccaa accacgttct gggtatgaat
    14641 tgaagcagct gatcacaatt ttttgggaag cccatcacag tcagatctat acaacgcttg
    14701 ccaagttaga ccagcagggt tatgtgaccg ttttggacaa agacgagcac tctcaaaaaa
    14761 agatctacca cttgactgat gaaggacgtg ctcttgtaga ggaatggatc aaagaggaaa
    14821 ctcccgctcc tacgcaaaaa gatgaatttc tagcaaaaat ctatgctttt tcgacgctcg
    14881 ataaaacaac agctactgga ctgctattca ctagagaaca acagctgaac aaaatcatgc
    14941 aaaaaaatca aaaaaaattg aatgacctct cgctagacaa gaaacaagaa tttggacgtt
    15001 atgttgtgat ccagcgcaga attatgcttt gtcagcagga actccaatgg tgtcagcaag
    15061 taagagaaca aatgcagcag ttttttgagt aagggataaa cagaaccttt ctagaaatat
    15121 ctattgaaga gcaaattatc ttcaataaaa gagcaataca gttggaaaag aaaaagcgat
    15181 ccgaacgaca ggccaaaacc tatcgttcgg atcactattt ttctagaact gcattcaaga
    15241 gactatgaca aaaagcatgc caaggccttt tttcaaataa cagtgttcca tcattcatta
    15301 ctttgaattg cttttagcac acttcttgaa agcgggccaa cgatgatcaa ctgcaacggt
    15361 aaagcggcaa tcacattcat tttccaagca ttcatataag cagagaataa ttgatcaggt
    15421 attccttgtt ccatgatcac accgaataaa gacatacatg tcaccattcc taaaaccatc
    15481 aagcatgaaa tagttaagat catttggacc ttgctttctg gatttactgg tagtttaaag
    15541 gcaatttttt tcgccagcac accgatgatg aagacatcca aaatgaaagc caccacgaat
    15601 ccaggcacta gaccaatcaa caaacttgat aaatgaagat cttgatgcag ccataaatta
    15661 tacgcgctca tccccaagac catcaaaaaa cacatcattg ttgtaaaaat tattccttct
    15721 tttttatttg taggcaatct gtaccactcc tttaaatttg tcacgaaaat catcgtagca
    15781 catttaaaaa tttctcgtaa gtactttttt tattttctgc ccttttattt cataaacttc
    15841 atcagccgta cgctcgacaa agtaagaatc atgagaagta aacaaaatcg ttcccggata
    15901 tatttgcatt agcttctcta aagcttcgat cgttgccata tcaataaaat tagtcggttc
    15961 atctaacagc aacacattac ttggcttagt aaaaagcaaa gcaatcgtca gacgggtcgc
    16021 ttctccccca cttaatgtac ataacggttt cgtcaaagtt tcctgagcaa accctaagtg
    16081 attcagcaaa ctacggacaa gcgattctga aaactctgtt tgtctcatga caaaacgaat
    16141 gatggattct tcagatgtca tttgataacc cttttgctga tatacttgaa agcttacttt
    16201 cggagagaga aggattcctt ctccttgttt gcggatatgt tctaataagg ttgtcttacc
    16261 tgaaccattt tcaccgacaa tcgcgatttt tttacctaaa gaaaactgaa aatcaccatt
    16321 taccagtaat gttctcccac ttctttccaa ttggacattt tgtcccatga tgggatagcg
    16381 gctgtggagt tcaagagatt ttggtactgg aaaacggatt tgtttcatct gctgcggctt
    16441 ggttgtttct cctatttttt ggagtcttct ctctaatgtt ttcgcattct tttggatggc
    16501 tttttgtaca ctgtcttttt gtttagagga agacaaccga tccagtctga tttgttgctt
    16561 tttcttttta ctggacactt tttccaactt ttccgcttgt tttttctttt cttggatcga
    16621 tttttccaat cgttttttct ctttcatgat cgactctgct tctcgtagct gagtcttttt
    16681 ctccaattcc ttttgagtga gataggcact ataattcccc gaaaactctc ggatttctcc
    16741 gtcttttact tcccagattt tcgatgctag ctcatctaga aaatagcgat catgactaac
    16801 aaaaaccagc gtaccataat aataacgaag ctcttcaatc agtcgatcaa tactttttct
    16861 atctagatgg gttgttggct cgtctagaag catcccttgt tcataagaag aaagaagacg
    16921 tatcaactcg atctttcgtt cttcccctcc gctccatttc cgctctgaag tttcttccag
    16981 tcttaactgg aaatgactgg ctaattccaa atttaggtcc tttgcttcag cgagataggt
    17041 taattgaggc aggtagttga aggtgatctc tgtttggatt ttcccatgat cgggaaaaag
    17101 ttcaccggct attagtttga gcaaagtcga tttaccgaca ccattttctc ctatgatccc
    17161 tatacgatct tgctgataga cacgaagaga atcaatagat agttctagct ggttgccaaa
    17221 gctgacttgt agatttgtta tatttactgc taaattttcc atatgtttta cactcctatt
    17281 tcatgtaaaa caacaattat cgatactaaa aaagagcaga aaaatctgtt tgcaaaaaaa
    17341 ctgcatcaca tcttttccta ctctgaacga aataactatg actaaatcac caaatctgtc
    17401 atagctttca cctattctac tgtcgttcga aaaaatggac atactccatc catgaaattg
    17461 ttgtttatac atgtcttttg aatttattta gttgttattc aaaagttcga aacgtaattt
    17521 catcgatgca gtcatttttc cgacctcctt ttttattagg ttaccacaca cgattcaaaa
    17581 aaagcaatag ctactgaata gtaactgaaa accttttatt cgaacatagt gatcttttct
    17641 ggtgctaaac gaacagactc gtaaccttct tctaccgctt ttcctattga taaaataata
    17701 actggaacat aacggtcttt atccaaacca aatgcctctg ccaactgatc tgcttcgaat
    17761 ccaccaattg gatttgtttc atagccatga tcacgcgcaa ctaacatgaa ttgcatagcc
    17821 gctaagctag aatcgacttt gactacatcg ttcatttctt ctcttgaaaa actcttgtaa
    17881 taaggaatga tcgcagctaa ttgttgatct ctgacttctt ttggcatctt ccctgattcg
    17941 taagcttggt tgtagatttc ttcgccatat tcgtaacatt gcatatcgcc aaaaatcatg
    18001 accattgcag aagaagtatc attttgtctc gtattgaaac ggatcaaagg acgcaagatt
    18061 tcttttgctt cctcgctttc agcgaccaca aagcgccatg gtttcatatt gacagaagaa
    18121 ggtgcagtcg tcgcttcttt gatcatttcc agcatttctt cgtgtgggat tttgtatgtt
    18181 tcatcatata cgcgaacgga tcttctacca gtcataattg ttgaaaaatc atttttttgt
    18241 tccattatta ttaacctctt tcgtttctgt tgttatattg caaagttggg tattcaattt
    18301 atctaaaagt gttagaaatt gtttcatttc tacatcgctg aaagccgggg atagcacgga
    18361 acctgtatct ttatggtcca tttcacaatg cttgattttc ttctgggctt tttctgttag
    18421 cgctacatac acttcccggt tgttctgagg atttctctga cgcgaaacat agccatttgc
    18481 ttccaatacc ttcagatgac gagtaactgc tccttgatca atctgcaact tttcttgcaa
    18541 actgctttgt agcaatggat tttcttcttt cagtctcatc atgatctcgt atctagtaag
    18601 acttataccg atattttctt caaagatctg gacgattttt tgatcggcta atttgatttg
    18661 atataaaagg tgactaatct cttctaaaga cataatttcc tcctttctaa taattgactc
    18721 gtcaacgatt gacttgtcaa taatagaata aaaaaagaaa aaagtcaaag aatcagctgt
    18781 gtaataaaaa aaacgctctc aatagaaaag tatagagaaa agaaattttt tgtagaatga
    18841 acggaaaaaa tgataaagaa agcacaacgc taaaaccaag attattgatt cttatcaaac
    18901 tatagaagat agctcttctg cagtagataa ttttacaccg ccaaaaattt ccgaaatcgc
    18961 cttttgcaag aatcccgtcg aatattagaa attggatcag tatgcttaaa cagtaataaa
    19021 aaagttatga caagatgttg tcacaacctt ttttgagtaa acggtgttca aaaacttgca
    19081 tctgcggtaa taagttcaac caaacaaaaa acatgaaaat ctgtttttgt ttggctgttc
    19141 ttactacttg atgcagggca gctttttcac tacctctttt taataaccat aaaatcctat
    19201 tccttcatat ctccagccca tcggtgttag ccaatctctt tccttagcac tcaaggtata
    19261 gtgatgggta ccagtttttt catttggatt aaatagtcga taaattggct tggaaccacc
    19321 agaataaaaa cttagacctt cataacgcca accgattttt gttaaagagt tgatctcaga
    19381 ttgtgccatt gtgtaatgat ggtctccact gtaaggattg tataaacggt agacaggttg
    19441 tccgctgttt ggtgcttgcc aagcaatccc ttcatattcc cagcctacag ttggcagata
    19501 atttttttct ccggcattca atgtatataa atgttctcct gtatgacggt tatacagacg
    19561 atacatcgga gaagttgaag ttggtgctgt atcatactgt gtcagattat aggtttcgat
    19621 tacattgttc aatgtagaac cataattagg cgcagtggca taacgacctg ttagccaagc
    19681 cgtagcatct ttgtaagagt tcgtattgct tttccatgca ccggaatagt agtaaacgcc
    19741 tggctgaaaa gaagtcgtct tcaataccgt tacgttatct tgcaatgatt ctttgtacga
    19801 aggatatttt ctaaaagcgg cattcaccgt aatccattgc ccattcacat attccgaagt
    19861 aggcatcgta acagattggc cattatagct tcctttaatc ccaaatagat tgtaattagg
    19921 ggcagaagcc aaagtactgt tcccccagcc actttcaacg atggcttgag caatcatgac
    19981 tgatgcatat aagtcattgg cacttgccaa actttgtgca gttgaggcaa tactatcaat
    20041 gaacgcttgt tgagaattag cagatgagcg agcataaaaa gcatagccag tatagttttc
    20101 gaattcagac aaatctgctt gatgggtatg tgtcaatgtt tgcccatctg tcaattggtt
    20161 cgtgatttct tctgcattct ctggattgtt ctgagcttct gctgatgtac tgtcttcggt
    20221 ttgtgtttgt tctgttgttt cagttgttgg ttcttcggtt gaaattgtat tttctgagac
    20281 agtagctgac tgcaaagtac tttctgtatc gttttcaatt cctgtttctg aagaactcga
    20341 tgtctgagtt gcgacagttt ctgtcgattc ttcagctagc actgttgtgt tggcaactgc
    20401 tagatttcct aaaagaataa cgctaaataa taaattcttt gctttcatct tttttctcct
    20461 ttgaattatg aaacttttcc taaataacag tgtaactaaa aaagtaaaag caagtcaatg
    20521 tccatattta aataacattt gtttcttttt aataaatttg ctttttctgc ataaaaagac
    20581 gtaaatgaag aatattcttc tccattcacg ccttaaattg atggtcgttt gaataactat
    20641 ttaacaagta attctctctg gatattatcc gttatggatt atacttcctg tgtcgtcgga
    20701 cggataatca tgttgctgac agacatccgg tctggcgttt ctatcgcaaa tgctacagca
    20761 gaagctatat cttcagatgt taatccccat tctttttgcg cttcatgaag ttcaagagca
    20821 gcctttttgt cgctgatggt ttgatataat tcagtttgaa cagctcctgg agagatgatc
    20881 gtagatttga tgttattttg ccgttgctct tgacgtaatc cttccatgat tgcacggaca
    20941 gcaaattttg ttccgcaata aacggcggaa tcaggataaa caacatgtcc cgccacagaa
    21001 tcagttgaaa tgatatgccc agatttttgt ttttccatga ttggaagtac ggcggaaatt
    21061 ccatttaaca cacccatgat gttgatatca agcatatttt gccattcatc acggtgacct
    21121 tcaactaatg gagcggttgg catgattcct gcattattgt acaatacatc gattcgaccg
    21181 aacttttcca tcgctaaatc gataactgct tggacttgtg caaaatctct tacatctgct
    21241 gtttgaatat atagctcagc ttctggtaaa gattctttta ttgcttttag gcgatcttct
    21301 cggcgtgcag ctataactag tttagcccct ttttctgcta atagcttcgt tgttgcttca
    21361 ccgattccgc ttgaagcgcc catgatgaca atcacttttt ctgataaatc attcattcta
    21421 ttctcctcct gttttgaaaa atctcttgct tatactcact atctcttatt tcatcttact
    21481 gttcaaataa tccgttcgac aggtttgacg attttggcag ggattcctgc aacgatggta
    21541 ttgtctggga catctttcgt aacagttgca ttcgctgcaa caatggcatt ctcgccaatc
    21601 gttacgcctg gcagaatagt tgctcctgct ccgatccaag catttttctt gatgtggatt
    21661 ggctttactg acaagcctct tcgttctttt ggatcggtta gatggttcac cgtgatgagg
    21721 ttgacacgag gaccaatcaa tactgaatct tctaaacaga tgccacctaa gtcaacgaac
    21781 atcacttgac gattgataaa gacatttttc cctatactaa tatgtttgcc gaaatctgta
    21841 taaaaaggca gcagaacagt caccgtatca tctactttgt cactaatgat attttctagc
    21901 cgtttgcgga tatctgctgg ttcatggtac ccagtattca gcgctgctaa aggctcttcg
    21961 ttttccgctt ggatctgatg gatcacttca aagagcggat ccgttactcg aatctcttta
    22021 ttgacgattt gtttttcgat gaggcttgtc attttgctcc ctccttttat ccttacttta
    22081 taacggacgg cttatgatgt ctaatactta taaaacatac ttaactattc cttttaacta
    22141 tacttagtgg tatgcttttt taaaaacagg agggaaaaaa tggatattcg tatactgacg
    22201 tattttttag cagtagctag agaaaaaaat atcagccgag cagcaaaatc tctgcatatc
    22261 acgcaaccta ctctctcaaa acaactgaaa gatttagaag aagaacttgg tgtgacactt
    22321 ttcactcgag gctcccgaga gatacagttg acggattctg gtcgatatct ttattcaaaa
    22381 ggaaaagaaa tcttgtcgtt ggtagaaaaa acggcgaaca atttaacaaa tgacgcaatc
    22441 atctctggag aaatctacat tggcggaggc gaaactaaag caatctcttt catttctgat
    22501 agccttcatt cgttgatcaa ggcgcatcct gatatccagt ttcatttata tagcgggaat
    22561 gcagatgata tcatagacaa actggatagc ggattacttg attttggact cgtaatcgaa
    22621 ccgacaaaca aacaaaaata ccagtcattt cgactgccag cccaagatcg ttggggactt
    22681 ttgatacatc ggaatcatcc tttagcaaag caaacagtca tccatccgca ggaactgaaa
    22741 actgttcctt tgatcatttc ccggcaaacg tcagtggaca gtcaactagc tgaatggcta
    22801 ggtttcagca tagatcagtt atcgatcgtc ggaacatata acttattgta caatgcttct
    22861 ttgatggtcg ataacgggac ttttggtgca ttagctctag atgggatcat caatacttat
    22921 gggacggaaa aagtattcat cccactcgat ccgccattac aagcttcact gaatctcatt
    22981 tggaaaaaag accagcctct ttctcctgct gctcgtaaat ttttagatgt cctaacggag
    23041 aaatacagtt aagtagagtt tttttccttc gctttcagct ttttaacaac gaataagtta
    23101 agcaaaagat ccaatgatta aataacataa gtttcttaat ttgttcctt
//
LOCUS       DAFLWC010000044        23110 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.045, whole genome shotgun sequence.
ACCESSION   DAFLWC010000044 DAFLWC010000000
VERSION     DAFLWC010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23110
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.045"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..132)
                     /locus_tag="L1V17_001593"
     CDS             complement(<1..132)
                     /locus_tag="L1V17_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBN1236366.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
     gene            542..841
                     /locus_tag="L1V17_001594"
     CDS             542..841
                     /locus_tag="L1V17_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1236367.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            914..2275
                     /locus_tag="L1V17_001595"
     CDS             914..2275
                     /locus_tag="L1V17_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBN1236368.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            2297..2557
                     /locus_tag="L1V17_001596"
     CDS             2297..2557
                     /locus_tag="L1V17_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236369.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2571..3323
                     /locus_tag="L1V17_001597"
     CDS             2571..3323
                     /locus_tag="L1V17_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBN1236370.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(3417..4022)
                     /locus_tag="L1V17_001598"
     CDS             complement(3417..4022)
                     /locus_tag="L1V17_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1236371.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(4075..5049)
                     /locus_tag="L1V17_001599"
     CDS             complement(4075..5049)
                     /locus_tag="L1V17_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HBN1236372.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(5427..6146)
                     /locus_tag="L1V17_001600"
     CDS             complement(5427..6146)
                     /locus_tag="L1V17_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1236373.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(6273..7544)
                     /gene="celB"
                     /locus_tag="L1V17_001601"
     CDS             complement(6273..7544)
                     /gene="celB"
                     /locus_tag="L1V17_001601"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBN1236374.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGIIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7697..9094
                     /locus_tag="L1V17_001602"
     CDS             7697..9094
                     /locus_tag="L1V17_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBN1236375.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            9175..9615
                     /locus_tag="L1V17_001603"
     CDS             9175..9615
                     /locus_tag="L1V17_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBN1236376.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9763..10089
                     /locus_tag="L1V17_001604"
     CDS             9763..10089
                     /locus_tag="L1V17_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBN1236377.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            10090..10839
                     /locus_tag="L1V17_001605"
     CDS             10090..10839
                     /locus_tag="L1V17_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236378.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10919..11374)
                     /locus_tag="L1V17_001606"
     CDS             complement(10919..11374)
                     /locus_tag="L1V17_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBN1236379.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11801..12076)
                     /locus_tag="L1V17_001607"
     CDS             complement(11801..12076)
                     /locus_tag="L1V17_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236380.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            12370..13185
                     /gene="thiD"
                     /locus_tag="L1V17_001608"
     CDS             12370..13185
                     /gene="thiD"
                     /locus_tag="L1V17_001608"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBN1236381.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(13514..14965)
                     /gene="cls"
                     /locus_tag="L1V17_001609"
     CDS             complement(13514..14965)
                     /gene="cls"
                     /locus_tag="L1V17_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBN1236382.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            15306..17972
                     /locus_tag="L1V17_001610"
     CDS             15306..17972
                     /locus_tag="L1V17_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBN1236383.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            18336..19088
                     /locus_tag="L1V17_001611"
     CDS             18336..19088
                     /locus_tag="L1V17_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBN1236384.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(19110..20264)
                     /locus_tag="L1V17_001612"
     CDS             complement(19110..20264)
                     /locus_tag="L1V17_001612"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HBN1236385.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYSLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            20449..22890
                     /locus_tag="L1V17_001613"
     CDS             20449..22890
                     /locus_tag="L1V17_001613"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HBN1236386.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
BASE COUNT         7433 a         4054 c         4806 g         6817 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactattag acaaatgata ttttacgagg aggaagaaaa
      541 aatgaaaaat cggttaattg tcgcatgtgg aagtggagta gcaacgagtc agacaatcgc
      601 tagtaagatc caaagtatgt tagaagatga cggcatcgca tttcctgtag aagcagttga
      661 ttacaaatcg attcaaaatg agcttctaac tgctggaatc tatgtgtatg tcgcacaacc
      721 tgatgaggaa gtacttgaac aagcaaaaga tttgggtatt gaagtatttc caggaattcc
      781 atttttaact ggaatgggtg tagaacctat ttatgacagt atcaaagagt tagtacagta
      841 aaggaggatt gttggataaa aaagttggtt catagtttta tttactatat ttagaaagaa
      901 agaaggttta tttatggaag ttttccaaac cattatcaat tatgttttga acttaggatc
      961 agccattttt gttcccctga ttattttgat acttggattg ttggcaggga tgaaattaaa
     1021 aaaagcattc atgtctgctt tgactttagg gattgctttt agcggaatgt ctatggtcat
     1081 tggctatatg tctaacgcag taagtccagc atcagaagca ttggctaaaa atacgggaat
     1141 cagtttgcct gcacttgatc ttgggtggac aggtgcagca agcatcacat ggtcgtggag
     1201 ttatgctttt atattttttg cagtaacgat tggggtcaat tttgtactgt tactttttaa
     1261 ttggacgaag acgttaaatg ttgatatgtg gaatgtttgg gggaaagctt taactgctta
     1321 tttagtttat tatgtttccg gtagtttggc tgcaggcttt cttactgcaa tggtccaagt
     1381 tatattggaa ttaaagcttg gtgatatgtt tcaaaaacat atacaagatc tcacagggat
     1441 tccattagta acagtgactc attttatgac atctgccgct gtcttgttgc tgcctttcaa
     1501 tatgatcatg gataaaattc ctgctttaaa taaacgagcg gatacgaatg cattgaagaa
     1561 gaaaattggg atcttctctg aaaactctgt aatgggattc attattggat tggggcttgg
     1621 ctttgctgct gcgtatggcg tttcaggttc tcttaatcta gcgatccaaa cagctacagc
     1681 attaagtttg tttcctatga tctctaaaat gttcatgcaa tctttgtctc ctctagcaga
     1741 cgctatgtca gaatttatga aaaagcggtt taaggatcgt gaagtatata tcggattgga
     1801 ctggccgata ttagctggtc gttcagaaat ttgggttact gctattttac ttgttcctgt
     1861 gtttattggt tatgccatta ttttgccagg aaaccaagta ttgccattag cagggattat
     1921 caactattcg attgcggtcg gcggattact tttaacagga ggaaacttgg ctcgtatgct
     1981 gatcttggga atcatcacta tgcctattta tttgtacggg gccacttacc ttgcgccaat
     2041 actcagtgat ttagcagaaa aaagcggagc agtcgaggga atcaagaaag gacagttgat
     2101 cacatggtca tccatagaag ggccggagtt cagggtttta tttgcggagg catttaatag
     2161 gaatattctc gctattgtag gatgcgtgat ttttctagga ctgtttgttc tactttataa
     2221 atatatgata aaagcgaaag taccgagtga acgttatgct gaactacaaa aatagcattg
     2281 aaatggtggg aaagtaatga aaagagaaga gacagataaa ataaaatgga cagtcgctct
     2341 ttgtggtaca cttctgctat ttctatatgg actctttact cagaatatca tcatcaatct
     2401 attggtcatt tttttcgcac tagtgatcta taaatatgga aatcacgttt tattcagaga
     2461 gtacgatgaa aaaagaaaac ggaaaataga agaatcaatg aaaataaaag aagctaccaa
     2521 agaaatattg agagaaaaaa gttttataaa aagataatgg aggggtcatt atgtcagatg
     2581 gacgtatgtt atttgagaga gaacgacagg acatggcacg tatcgtaaga gtgattttcg
     2641 aaaggaaaaa cacaaatgtc gcaggaggga atttttcctt taaaaccact gatgatcaag
     2701 ggaaagacta catcatcatg acgccgacca tgatgtcaga agcctatcta ggagagattt
     2761 ctcctgcaca ggttctagta gtagaaccaa gaacgcgtag aatcgttgac ggagtcggtc
     2821 atttaactcg tgaaatcaat atgcatgaag cgatgtatga gactaatcca gctatcaaag
     2881 ctgtcctaca tgctcatgcg cctaatgcaa tgttctgggc gactactggg ttgcctatgc
     2941 ctaatttgac agaagccaca gctaaagtaa aagagattcc tgtcatggac tttgagccta
     3001 attgctctga agaacttgct gaattgacaa gcgactatgt aaaaaaacag catctcgaat
     3061 taccgcatat gttgctgctc aactctcatg gcgtattgat caacacaggt ggagaatcag
     3121 gaatcgaagc tatccataaa gcactgcaaa tccttgatac agttgaatgg aatgcagaaa
     3181 ttgcctacaa gcagacgatt tttcaagcat tagggattac tgacggtttt tattcaaaag
     3241 gtgagaaaat cgggggattg gaagagttga aacataaaac ggctatttat aataaatctg
     3301 ttattgcagc tggtggagac taacctatct gacacaaaaa actacgactt tcacaaaatc
     3361 tgatccagat cgatatctgc ttcaggttgt attatgtaag tcgtagttct tttcttttat
     3421 ttagttaaga ggtggtctgt ccattccctc gcttgcttga tttcgtccat cgtcaactga
     3481 tgacctgtta cagttagctg aatagtcaca tttgcttggc gtgtttcgaa ttgatcggcc
     3541 aattctttaa aggaagcagg ggaaacgatt ggatcgttat caccataaga aatccagacg
     3601 gttttatcct ctaatgtgga acggctttga tgaacaccta gagacatcgg atggaaaaac
     3661 aaccctttat ttagctcggt ctcacgctcc aataataaat gagcagcgat gtttgcgcca
     3721 tttgaatagc cgacaagcag ccagtcactt aacggtatca gttctttttc gctgatttct
     3781 ttgatttttt catggagttt atctgtttct ttttccaaac tgtccaggtc gaattgattc
     3841 aatccattac gcttgaaaaa acgattcatc ccatcttctt ggaccgtgcc acgaaaagaa
     3901 agcaatgtac tgtttggtgc aagaaagtga gcgatatcca gtaaagaatg ttcatcgcca
     3961 cctgtgccat gaagtaagat caaatgcttg ccacttgttc ctttttcaaa aatgtaggtc
     4021 attttgttcc ctcttttctg tttctataga tgcaaatgaa gtagcatgaa gagattattc
     4081 acgtttttta tttgcatcac ttgtatcgaa aggacggaca taagcttcaa tggcttcacg
     4141 acgttcttct aagaatggag gaagagatag tttttctcct gctgattctg ctggttcatc
     4201 ttcaaggaat ccaggaccat cagttgctaa ttcaaacagt acgtgatgag cggctaggaa
     4261 gtactcagat tggaaataga aacgatcgac gaaaccagaa tttggcaatt caatcttatt
     4321 gattacttga atccagtatt ccaatgcttc tttgtctgct acacgcaatg ctaagtgatg
     4381 gatatttcca aatccttcga ttgcttttgg caagtctgtc cgatgttcaa taatgatgct
     4441 tgcaccattt cccccttcac cgatttcaaa taagtagaaa tctcctgaat ggtctgtttc
     4501 tttgaatcct aagatttttt caagaatcaa gcggatatgc tctaattgac tgacacggac
     4561 aaagacaggt ccaagtcctg tgatcgcaaa ctctgtcggt acattgctgt ttttccaagg
     4621 aatgccagct gctacacctt gattgttttc gtcagagatc aattgataat actgattatc
     4681 gaaatcttca aattcgatat attttttgcc gaaacgttca ttgattgctg aatgagtaac
     4741 gtcatatttt tcaaaacgtt ccaaccaaaa gtctaatgct gcgtcacttg gcacacggaa
     4801 agaagcacga gagatcgtat ctgttccttt ttttcctttt ggctgatttg gaaaatcaaa
     4861 gaaagtcata tctgttcctg gcgcaccagt atcgtctgta aagtaaagat ggtaagtttc
     4921 gatgtcatct tggttaactg tttttttgat taagcgcatt cctaaaatat ctgtaaaaaa
     4981 gcggtagatt tttgtagcgc tagatgtcat tgctgtgacg tggtgaattc ctctgatttg
     5041 tgtatccatg ataaatttcc tcctgttaac ttacaaaaag taagtagttg atttagacat
     5101 agtatagagg gtgcatctct attttgcaat taatttgtct tctaaagtat caggaaggaa
     5161 tcaagaatgg aaaagaggag ggacggatca ataaaataaa aagacttacg actagctgta
     5221 tcgatttcaa aaaaactagc tttaaaaagc taactttaga atcattacgg gtggtcataa
     5281 gtctttttat gctgagttat tttttcattt ttgagctaat gcttaggata gaatagaatg
     5341 ttgatttcac gatctcttct tgttacttga aactgcttac cactgtcacg atctcttggt
     5401 aaacggcttt ttcacaacct ctttggttaa gttgaacgca catccagcac agaatagttc
     5461 cgaacatcaa atcggtttcg gctggaagaa tattcaatcg gctgtccatc tttgagatag
     5521 acgacttgct gaacttccag tacaggatcg ttttctgcac agttcaaata ttgctgatca
     5581 tattcatcac ttttatctgc agaaatagca cgataagccc ctgcaaaatg gacattcaat
     5641 tcttgatgaa gatgatcata gatagaggct aacaaatgtt ctttttttaa acccggcaca
     5701 agatggactg gcataaaggt atgctctaaa acatatggct cgccatctaa gatccttaac
     5761 cggtgaatat tgtagacagg ttgctcggca tcgatcatca atcgttcttg gatatattga
     5821 ttagggaatt caacatcaaa atgaatgatt tgactcttca aagaacgatg tctgcgtttc
     5881 atttggagac tcaaaccttc atactcgtta gcgggcgatg tgtctttttg cataaatgga
     5941 tgattcaaga ttttcgttcc tgatcctcgc tgcgaataga caagtccttc cattgctaag
     6001 atattgatgg cttttttgat tgtcatccgg ctcgcaccaa attcttttac caagtcgact
     6061 tgattaggca aaaaactatc gagaggatac tcttttgaac ggatacgttc tcttaaaata
     6121 tttgcgattt cttcgtattt tggcacgtta ttcacctctt ctagagtata acgaaagatt
     6181 atgcttccga caactcgaag tagcatctgg aacattgttt attcgaaaaa agaggtcatg
     6241 acaagttttt gtcacaaccc cttaatgatc tattaagcaa tatctaaatc tggttgttta
     6301 tctagtactt tcaggaatgg gtaccagata aaggcaacga tgacaaagtc gatgacttgc
     6361 agcataccac caagccatga atttgttgct aagacaccgc ttgcaatgat tggcacagtc
     6421 catggaacag agacgccagt tggtgcaggg acaagtccag cagccattac caaataattg
     6481 aacgtcgtta cgattagagg tgccacaacc caaggaataa ggattgttgc attcaatacg
     6541 atcggtagac cgaagatcgc tggttcattt acattgaaaa taccaggtgc taaagctaat
     6601 cgtccaacat cacgatactg tttcttttta agaacaaagg ccatcaataa aacgacagct
     6661 aaagtcattc cagagccacc aataccaaca gtgaaggttt ccatgaatgg ttttgtgatg
     6721 atgtgtggta attcttttcc atgttgataa gcttctaagt tatcaagcat cagtgtattc
     6781 caaatcgggt ccattacaga gttgacgatg atttgtccgt gaagtccgaa gaaccataag
     6841 aattggacaa agaacaaagc aatcaatgtt gcaggtaaac tacttcccaa accagttaat
     6901 ggtttttgga tcacttcata aacgacgtca tgtaagttag cattgaaaat accagtcatc
     6961 acagcattga ttactaagaa aatagttagt gtcactacag cagggatcaa agcggcaaat
     7021 gattttgtta ctgcaggcgg aactccatca ggcattttga tctgccagcc gcgtttcgtg
     7081 attctgcagt agatttctcc agccaagaaa gcagcgatta ttccaatgaa cattcctttt
     7141 gcgccaagac gatcaagtga aagcacacca gtcacatctt caccgccagc ggttttcatt
     7201 gcaaaaggcg taagaatcaa gaagctggca aaagacacgg caccaccgaa aataccttca
     7261 acgtcataag attttgataa ataatagccg ataccaaaag taacaaaaac cgacatgatg
     7321 ctcattgttg cattttgccc attaccgaat aaattcgata aagttccctt tgttgcgtca
     7381 ctgaaaaaag gcaagttatt gataacgaca acgatcgaac cgaacatcgt taaagggaag
     7441 gaaagcatga aagcatcccg cagcactgta aggtaacgat tttgccctaa taaattagct
     7501 aagggcatga ttttctcaga aagcttgtcc ataaaaccgt tcatttttat tcacctcaaa
     7561 tttatttgca atcgattaca tacaaagtat aacgccaaaa attttaaatg tctagtcatt
     7621 ttcataaaaa gtattgattt attttttagg gttcgttatg attacggtat caagaaaaaa
     7681 gagaggaagt aaaaaaatga aaacctacac attcccagaa aatttttggt ggggttctgc
     7741 tgctagcgga ccgcaaacag aaggaagagt aagtgatgat ggtaaaggag aaaatatttg
     7801 ggatcattgg tatgaattag agcctgaaaa attcttcgat caagtaggac ctgaaaaaac
     7861 ttcgcaagtt tacacaaaat acaaagaaga tgttcagtta atgaaagaaa ctggccataa
     7921 cacatttcgt acatctatcc aatggagtca tttgattcca gaagggacag gtgaaatcaa
     7981 tcaaaaagct gtttcttttt atcgagatta ttttactgaa ttgctggata atggtattga
     8041 accttttgtg aacctttacc atttcgatat gccactacca ctgcaagaaa aaggcggatg
     8101 gttatcaaga gaaacggtcg acgcttatgt ttcttatgca gcagcgtgct ttgaactgtt
     8161 tggagatctg gtcaaaaaat ggtttactca taatgaacca atcgtacctg tagaaggagg
     8221 ctacttgtat caattccact atccaaatca tatcaatatg aaagaagcgg tccaagtagg
     8281 ctatcatgag aatctagcaa gcgcaaaggt aatcaaagcc taccatgaag gcggacatga
     8341 tggtgagatc ggaatcatct tgaatctgac accaagctat ccgagagatg aaacgaaccc
     8401 agaagatgta aaagcggcga agatcgctga cgcattcttc aaccgatcat tccttgaccc
     8461 tgcagtgaaa ggagagtttc cacaagagtt gatcgaaatt gtcaaagaat tggctataat
     8521 gccagagatc catgaaggag acctagaact catccgtgaa aacacgattg acctgctagg
     8581 aatcaattac tatcagcctc gtcgaatcaa agcaaaagaa actccaatca atcacgaaca
     8641 tagccccatg ccagatgatt attttgataa ttacgacatg cccaataaaa aaatgaatcc
     8701 atatcgtgga tgggaaattt acgaaaaagg aatctatgat attttaacga atacaagaga
     8761 aaactatggt aatatcaaat gctatatttc tgaaaatggg atgggggtcg aaggagaaga
     8821 acgatttgtt aacagcgaag gaattattga agatgattac cggatcgagt ttgttacgga
     8881 tcatttgaaa tacgtccatc aagcaatcca agaaggaacc aattgtgtgg gttaccacat
     8941 gtggacatgt atggacaact ggtcttggac aaatgcttat aagaatcgct atggctttat
     9001 cgctgttgat ttggcacaag acggtaaacg gacgatcaaa aaatcaggtc gctggtttaa
     9061 aacggtctct gaaaaaaacg gatttgatgc ctgatatttt ttgataaaac gttcacaaaa
     9121 tgtttgttct aacactgtaa tcgtgctaca ctaacagtga aggaggcgtt tacaatggta
     9181 gatacttatc gtaatatttt agtagcaatt gatggttctg aaaaggcaga aaaagcattt
     9241 cttgaggcaa tcacgattgc caaacgaaat caggcaacgt tgcacatcct gtatgtcaat
     9301 gaagtaacag gcaattactt tggtgatttt gcatttgtta caacaagcct tcaggaagaa
     9361 ttggatgagg ttgcggaaaa ccagatgaaa gaacatcgaa acttggcaat tgaaaaaggc
     9421 ctgacagata tcgagacata tgttctttac ggttatccaa agacactgat tgctaatttc
     9481 catgaatcga aagaaccaat cgatctgatt gtcatggggg cgacaggtct gaatgcggta
     9541 gaacgtgcac tagtaggttc cactacttcc tatgtagtca accacgcatc atgtaacgtc
     9601 atggttgtaa aataaataaa ttaagggaac agaaagcaaa aaagcataac gcttcttttg
     9661 ctttctgttc cttttatttt tttgtaaaaa attactttac ctgatgaagt aatcatgcta
     9721 ttctaattac aacgacagat ggagtaatat ggaggaaaga aaatgatttc aagtgatgga
     9781 atacgcggat acaatgatgc gattatttta tcgatcctta acaaaaacga ttcttatgga
     9841 tatgaaattt ctaaaacgat tcgtgagagg acaaatgatt cctatgtgat caaagagaca
     9901 acactttact ccgtttttgc ccgtttagaa aagaatcaac tgattgtttc gtatcctgga
     9961 gaagtgactc atggaaaaaa gcggacatat tataaaatca ctgaaatagg gcgtaatctt
    10021 ttagaagaaa aaaagcaaga gtggctgacg acgaaagacg tagtcgatca atttttggag
    10081 ggaaattaaa tggatacaat ccgtaattat ttagacagtc tttttatcgg agtacctcaa
    10141 agtaccgaga tagataagct gaaaactgat ttgttggcaa atatggaaga ccattatcat
    10201 gaattgatgg gagaaggaaa aaatgaacag gaggccatcg gtacagtaat ttcgacattt
    10261 ggttcaatcg atgaattatt agaagaacta gatgtcgaaa aaaaacatca agctgacgag
    10321 acggaaacaa acacagcttc tatttattta agcgaagcag aaaactactg gaaagaatac
    10381 agagcggcaa gtctccaagt ggcatcaggt gttctattca ttagcttatc ttttgcaagt
    10441 tttcttttct tttgttcagc aggatatgtg ttcatgggta tttcttgtct gattttcggt
    10501 atagcattag ctgtcggttt ttttattgct tctggtatga aaatcacacg tttaaatcac
    10561 tttttgcacc atcggaaaat acctgaaaaa gtattagcag aagcaaaaga aaaagaagaa
    10621 gagtatcagc gaagttttgg cttctcactg attgcaggaa ttggattatg tattttttca
    10681 cttttcccac ttttggcttc tttaatgtgg tatatggatg gtagtatcgg tgcctctata
    10741 ttttttgtta cggtaggaac gggtgtcttc ttgatcattt atggcagtct agtccgtcat
    10801 tcttatcgtc aattcactca aagcgcttat tactggtgaa tgtattcaga tttgtaaaaa
    10861 tattctattt atccggcgta gaaaaaaaga ctgtgacacg cttttgtcac agtctttttt
    10921 atatataata atttaaaaat tcatcatcta aatccgtaga attttctaga ttgcttaccc
    10981 atgtaaaatc gttatagaca gatttcagtt gacttctgcg ccattgtaca gggataaaaa
    11041 gacgcatgct atcttcattg aatccgacta ataatttctt tccgtcagta atgatgggac
    11101 gttgtaacaa agtaaaatgc gagacgatca gatcgacaag ctctgaggtc gtacattggt
    11161 cgatttggtc tttcaaattt ttataatcaa tcgagcgttt agctaataga tcgtcaaatc
    11221 cgttttctgt taatgacaat aaataaaata tctctttcct tgttaaaggc tgtttaggtg
    11281 tgaaaattcg ttctctgtaa ggcatttgat ggtctttcag ccagtttgcc atcagatggt
    11341 aactatgtgt gcgagaagaa tagatcgtaa gcataaaaaa actccttaaa tagtccatta
    11401 atttgttaga tctgttgaga taaataatag gtaaggagct gtgcataagc attgatcaaa
    11461 acaacccaaa catcattaga aataactttc taaagtctta aacttgcgac gagaagcaac
    11521 tagactaata gaaaaaatgt cttagccatt tggcttcctg tttgtttttt tgcttatgct
    11581 gcagctcctc gggaaagggt tctaacaatt tgaagaaggt tgatgattga tctagtttaa
    11641 attgtgtgaa atttgaaatc tggtgttttt actagatgaa tcacctaaca actatgatta
    11701 taacttatag aacttctgtt ttgcattcgg ttttgttata gttgttataa agttttattt
    11761 tattacagaa catttttaat taataaagaa cagttagaag ttaaaattgc tgattcacat
    11821 agagtttatg acttcttgga aattcttttt caatcagttt tttcatctgt ttatgaaatt
    11881 cttttttttc agtaaacata aaggtttggg tatcgtaacc ttcttcatgt aggaaataga
    11941 ttattccttt ttctgtgttt tgcgtataag cttttatact cctgtctttt ttgaaagaac
    12001 agatcgtata gccatctatt tggtctggta gtcgtttgat tttcttcaaa atgacttttt
    12061 tatcctcaag tttcattttt ttcacctgac tttatttttt tcatatggaa atcatagcgc
    12121 ctttggttat atgaaaacaa gaaggatact gaaatatata taaatcaaat agtggttatt
    12181 tattattaga atagcgaata caaataaacg accactattt tctgatttat tgcaaatgtt
    12241 ttttcaaata aatttgatta ccaagaaaag gtagtggtat atttactgag ggatactttg
    12301 aaaaacatat gatagaaaca gtaacagtat tatgaaaaat ctttttataa aaatggagga
    12361 atcgatttga tggaagatca gtatgtacaa gcaatgacga tcgcaggatc agatagcgat
    12421 ggaagcgcag ggatgcaagc agatatgcat acattcttta caagaaatgt ttacggtgtt
    12481 tctgtcatga ccgcatgtgt tgcaggtaat tcttacggaa tcggagcaag tgtgacattg
    12541 ccaacagatt ttatcgacaa agaatttgaa ctgattgcga aggactttca aatacgtgca
    12601 gctaaaacag gtatgctagc agattcaaag ttgattgaga cagttgtaaa aaattaccaa
    12661 aaatatgatt ttggaccatt agtcgtggat cccgtaatcg taacgaaaca tggaaatctt
    12721 ttactagaag aatctgcttt gcaaagcttg aaagaaaagc ttgtcccttt ggccgaagta
    12781 ctgacaccta atttttatga agcagaaaag ctgactggac ggacattagc agctgaagaa
    12841 gattttgtgc aagcagcaaa agaactgcaa gatatgggtg caaaaaacgt tatgatcaaa
    12901 ggacatcatg ctaaaaatgc gcagcaagaa acagtcaatg actacgtatt gttcgaatca
    12961 ggaaaatcat tttggttaaa tgcaccattt tatcctaccg accggatcaa cggaactggc
    13021 gattcgctat ctgcatgtat tgcagctgag ttagcgaaag gaaaaacagt tgaacaagcg
    13081 atccgattgg caaaagacta tgtaaaccgt gcaattcgtg aagaaataaa tgtagggcac
    13141 aaatatggcc ccatcaatca ttgggcagct ggtgaattag agtaaaagaa agaagttgtg
    13201 aaaaagttgc cctgcatcaa gtaataagaa cagccaagta aaaacagctt cttatgtttt
    13261 taacttggtt ggacttatta ccgcagatgc aagcttttga acaccgttta agaaagaggt
    13321 cgtgagcctg ccgtccagct ccgagtcaca aggaacaagt tcaaaaaaca gcttctcatg
    13381 tttgttgaat attgtgactt gtgaccgagg agttggcagg agaacaccgt ttgttcggaa
    13441 gaagggactg tgacaagatt tttgtcacag tccctttaat cttagtatat ttttctctac
    13501 ttgaataaaa aaattatagg attggagaaa ataatcgaga aatttgttgc ttgaataata
    13561 gccagttaga catttccttg actgtttcag ttgtcatgga tgaacaatgt gtctcatctt
    13621 ctttgaactg agtagcaagt tcttctaaaa actcaggatc gtaaatgaca gcacttgttt
    13681 caaaattcaa tcggtagcta cgaatatctt gatttgctga acctaccatg cagatttcat
    13741 catccattat caatgttttt gcatggagga agccgttctc atagacaagg atttgtacat
    13801 tttccttgat cagctgccga gcataatatt gtgttgctcg ataaataaaa ggatgatccg
    13861 gtttgttggg aatcatgatt ttcacatcta caccagaggc agttgcgatt tttaaagcag
    13921 caatgacact ttcatcagga acaaggtaag gtgtctgtat ccaaacacgt tttttagcag
    13981 aagtaatcaa tttgataaat gaaagcttga tttgttccct ttcgttattc ggtccgcttg
    14041 aaacaagctg gatggatgta tcagcaagct tagattcatc tcgatctgct tttttaaaga
    14101 aataattcaa atgatagccg accttttttt cttcaggtac cgagacgttc cagtctgtta
    14161 agaagcgaag ctggagcaaa gaagaagcgg caccgaaaat ccgtatatgc gtatcgcgcc
    14221 aatagccgaa tttttttgtt gtatttacat attgattggc aatattgaaa ccaccggtat
    14281 aactaatctt tccatcgatc acaacgattt ttcggtgatc atggtaattc aatcggaaac
    14341 gaagtaatgc cctttgtgag gtaacaaatg tatggacatg tccaccattt ttgattagac
    14401 gattgaaatc ttttgctttt gtgccatgag agccaaatgc atcatataat attcgaactt
    14461 ccacgccttc tgcggctttt tcttctaaaa catgtaagac ttgctggccg atattatctg
    14521 tcacaaatgc gtaatattcg atatggatcg aatgtttggc tttttttaga tcttgaagca
    14581 gtgaatccaa tttctcttgt ccgtctgtga gaagagtgac agaattcatt cttgtcagcg
    14641 gcatacgatt taatgaagag aagaagtcaa caaattgctg tttgtcttta tcgcccatgt
    14701 caggatcgta atgttcaatg gtatctcctc taaaagactg aaagttttct aattctttca
    14761 agtcactttg tcggagatag aattttttct tatccgttaa tccacgtccg aaaaataaat
    14821 ataatacaaa gcccacccca ggaagggcaa acaatactaa gagccatgcc caaatggctg
    14881 ctacatctcg gggtttgatc aaaatagcca ccaaagcaat aagtgcattt aatagataaa
    14941 gggcggttat aatactagat accacaaaaa tgttcctcct tacatacaat aacattagta
    15001 tagcatgata gaagaaagaa gcctaccaag gtgaatatac ttttcactcc tttcatgaaa
    15061 atgtaggtaa atcgggctaa agtagttgct ttttgtaggt taataaggta ggatattagt
    15121 acagttgaat atctccttag gggagtaacc ggcaacgttt gttgcgataa tatcaacagt
    15181 aagttaacca aatggttttc tggtattgta tgaaatggtg agacctaaga caaatgcgta
    15241 tttgtcttag gtctcttttt tttcagacag gactagggcc aagatcaaaa aatgggggat
    15301 gaaatttgga aaacaaggaa caagcacaac aagcggtcta taaagaaacg atcgactcgt
    15361 tgatgcagca aacgcagagc tcaaccgatg gattgagcac cacgcaagcg aaggaaaaat
    15421 tagaaagaga tggcttgaac cagctaaaag aaaagccgaa gaagccaact tggaaattgt
    15481 tcttagaaac tttcaaagat gcaatggtta tcgtattgct gattgtcgca ctgattcaga
    15541 tggtcatggg tgactacatc gaattcttag ttatttttgc agtattgatg ttgaattcta
    15601 taatcagtgt tgtccaaaca aaaaaagcag aaggttcttt agaagcgttg aaaaaccttt
    15661 cagcgcccga tgctcgagtg attcgtgatg gtaaggaaaa aacgattccg gcaaacgaac
    15721 ttgtggtagg agatatcgtg ttgttagacg caggcgatta tgtacctgct gatggacgtt
    15781 tactagatgc gggatcatta aaagtagatg aaggtatgct gacaggagag tcgacttctg
    15841 cagaaaaaga agtaacggat atcacaagta cggtaccaat cggagatcgt acaaatatgg
    15901 tattcagtgg aacgatcgta acttacggac gcggtaaatt cttagtgact tcaactggga
    15961 ataatacgga gatcggacaa gttgctggcc ttttggaatc aacaactgag caagtcactc
    16021 cgttacaacg aggtctggat aaattcagta aaaaactaag tttggctatt ttggcattgt
    16081 ctttattgat tttaggtatc caactgtttc gtatttatct tggagaaggt acaggagata
    16141 tgactgcaga tatcgtcagc gcagtgatgt ttgccgtagc cgtagccgta gctgctattc
    16201 cagaagcatt acagtctatc gtaacaatcg tgttatcttt gggaacgaat aaaatggcaa
    16261 aacgtcatgc cattattcgg aagcttccag cagttgaaac acttggttcg acaagtatca
    16321 tctgtacaga taagactggt acattgacac aaaacaaaat gacagttgtt gactactttt
    16381 taggtaatgg cgatactggg gatttcacaa atgacccttc aaaatggaca gctgacgaac
    16441 gtcgcttgat cgaaatcagt gttttagcga atgatgcatc gatcagtgaa gacggtacta
    16501 aattgggcga ccctacggaa gtagcgttta tcgactttag tgaaaaatta aaccagcctt
    16561 atcaggaaat ccgaaacaac tacccaagac aagcagaact tccttttgac tcagatcgaa
    16621 aattaatgtc tactggacac acaattgata acaaaaatta cttgtttgtt aaaggcggac
    16681 cagatatcgt cttccaacgc agtaaaaaag tattgctaaa tggtgaagtc gttccgatga
    16741 cggatgaatt gatgaaaaaa ttccaagagc aaaatgaagc tttttcaaca cgcgcattac
    16801 gtgtactagc ttttgcttac cgtccacttg ataattttga tttatcattt gaagatgaag
    16861 acgatttgat ccttgttggt ttgcttgcta tgatcgatcc tccacgtgct gaagtgactc
    16921 aggcggtaac agaagcaaga agtgcaggaa tcaaaacaat catgattact ggtgaccaca
    16981 aaacaacagc tgttgctatc gcaaaacaaa tcgggatttt tgaagaagga aacctggctt
    17041 tgaccgggac ggaactagat gaattgacag aagatcaact aaacgaagtt ttagaaaaag
    17101 tcactgttta tgcacgtgtt tcacctgaga ataaaattcg tatcgttcgt gcttggcaaa
    17161 ataaaggtca tatctcagct atgacaggtg atggtgtaaa tgacgcacca gcattgaaac
    17221 aagcagacat cggaattgct atgggaacgg gtacagatgt ggcaaaagat gcagcagcga
    17281 tggtattgac ggatgataac tttgcttcta ttgtcagcgc agtagaagta ggacgtaatg
    17341 tgtttgataa tatcaagaaa gctatttctt atctatttgc aggaaattta ggtgcgatca
    17401 ttgcgatcat ctttgcctta gttgctgact ggtccaatcc atttacagca ttacaactgt
    17461 tgttcatcaa tttagtcaat gattcactgc cagcaattgc attaggtaca gaaaaagctg
    17521 aacctgctac gatgaaccgc ccgccaagag atccaaattc aggaatcttt acggacaaaa
    17581 cattgatttc tgtaacgtat cgtggtgtgc tgattgggat tgctgttatc tttgctcaat
    17641 ggcttggcat gcagcattca cctgaattcg gtgtagccat gtcattttca acattgattt
    17701 ggtgtcggac attgcaaaca ttcccagcac gttcaaacac acaaacagct atccaagcag
    17761 ggttcttctc taacagaagt gtcttactag ctgtagttgt atgtagcgcg ctttactgct
    17821 taacaatgat cccaggactg aaagaagtct tctctatccc atcagcattt ggattgacag
    17881 aagtctttac atgtatggga atcgcacttg tgacaattgt tttgatggaa atcactaaat
    17941 tgatcattgt acgagtacaa ggaaataaat aaaacgaatc aacgaggttg tgagcctgcc
    18001 gtttaattct gagtcacaag gtgcaatttc aacaaacagc ttctcatgtt tgttgaatat
    18061 tgtgacttgt gaccgaagag ttggcaggag aacaccgttt aaggaagaag ttgtaaaatc
    18121 agcattttga gctaatactg agggtcatct gattggacac tgtttattcg gaaagaggga
    18181 ctttgacacg actttggtca cagtcccttt ttttatttat gatagacgga aagccaatca
    18241 ttttattatt catcaaaaga gatagaatag ataaaagagg agaatgattt attccgaaaa
    18301 gtgaaaacat ataacaaaaa attagaggaa atcaaatgaa tgaaaaagaa tgggatgaat
    18361 ttgctgaaga atattatgaa atccagcaag aatcgcaagt aactattgct gaagatgtaa
    18421 aaaattatct gaaaacggag aaagtcctgc ctgctgaaac agcagcagac gttgctggag
    18481 gatctggcag atttctttcc ttagcaaaag aaattaatcg ctatgatttg atcgattttt
    18541 cttcaggaat gctagaaaat gcaaaaaaag aagcagaaaa aaatgagttg ccaaatgttt
    18601 cctttatcaa acagtcgtta gaagaattta tccaatcaaa tgagacatat gaaatggttt
    18661 ttacagcagc aaatccagca ttggtacatc ttattcaatt agaaaaattg atgaaaaagt
    18721 caagcaaatg gtgcgtgata atcagagtag tggaatcaat cgatgatgtt ttttatccta
    18781 tcgaaaagca actaggaatg atagaagaag atcctaatac atcgccagtt gtaatggatc
    18841 aatttgaaac atacttaatt gatgaaggat tcaaagtgaa gaaaaaagat tttacttatt
    18901 ttacacagga atcaattact gaagaattga tgaagctata ctatgacgcg tacgcaaaag
    18961 atcctgttgt gaccaggtac attcgcaaac tattcagtga aaaacgagaa atccttagta
    19021 cgactaagct gacctataga ctgctccttt ggtccgcaga taaaaaaaga acctttcacg
    19081 actcgtgaag ggttcttttt atgattttat tatattttgt agtaacgaat atcattttcg
    19141 atctttgtaa tcgaaaaagg tacatctgaa gtatattctg cacattctcc gtgttcagga
    19201 agcgtctcac tgaaaatcgt ttcatattcg tcaacagtga tccgtgttcg agaatctagc
    19261 atctcttgat gagattgtgc gaagagatat tcttgatagt tttcttccag ataacctgta
    19321 aaaaattcac ttactgcacc agaaccgtag ctgaatagac cgatgcgatc tcctggctgt
    19381 agtgatttcg aattttccag tagagaagtt agccccaggt ataatgaacc agtgtaaaga
    19441 ttaccgattc gtcggctgta acggatgctt tcttcatagc gagccataag acgttcctga
    19501 ttttcttcgt ctgtttggtc taatacgctt tgcaatgcct tttttcccat cttagtatac
    19561 ggaatatgga aagcaatcgc ctgataatct tcgagtcctc gacccgacaa ttctttatgt
    19621 cgattccaaa ctttttggaa tgattcgata tacgtagaat tagataaagg accatcaaca
    19681 acaggaaatt cgctataatc tggacgccag aaatcataga tatcttctgt cagaaatacg
    19741 ctgtcgtctt caatcgataa aatacgcggg ttttgagtga tcatcatcgc aacagcaccg
    19801 acaccttgcg tcacttcacc accgcttgcc aagctgtaac gagcaatatc acttgctatg
    19861 actagtactt ttcgttctgg atgatttttg acatattctt tcgccatgtg caaagctgcg
    19921 gtgccaccgt agcaagcctc ttttacttca aaagaacgag caaaagattg gattttcagt
    19981 aaatggtgga taattaccgc actcgctttt gaatgatcaa tcccggattc tgttccgacg
    20041 atgaccatgt cgattagctc acggtctttt tctgttacga ttttgctggc agcatttgct
    20101 cctagtgtaa tgatgtcttc atttgcacga ttgactgcca tttggtcttg accaatccct
    20161 atatggtatt ttgcaggatc atccccacgg ctttctgcca actctgtcat atctaaatat
    20221 aaattaggaa taaaaaagga aagacgatca atccctattt tcatttcaac acctctttac
    20281 ttatgataaa aaacttactt tactaaggta tcataaaaag attaaaagaa atataaaaaa
    20341 gagaatattt aaggattgtt aaaatttaat cttagaaaaa aataactgga acaagagcta
    20401 tttgttttta cagcaaagaa tggtatattt ttgtaggagg tggcttactt gaaagaagtc
    20461 gttatgatag atgctgcaag aacgccgata ggaaagtatc gcggaagttt aagtccattt
    20521 actgcagttg aattaggcac acttgtgact aaaggattat tagataaaac aaaactgaaa
    20581 aaagataaaa tcgatcaagt aatatttgga aatgtcctgc aagctggtaa tggtcaaaat
    20641 gttgccagac agattgcttt gaacagcggt ctccctgtag atgtcccagc aatgacgatc
    20701 aatgaagttt gcggatctgg tatgaaagca gtgatcttag cacgccagct gatccaatta
    20761 ggtgaagcag aacttgtgat agccggcgga acagagagta tgtctcaagc acctatgctg
    20821 aaacagtatc agtcagaaac aaatgaatat ggtgaaccaa tttccagtat ggtcaacgac
    20881 ggattgactg acgcattttc aaatgcacat atgggattaa ccgcagagaa tgttgcaaca
    20941 caattttctg tgagcagaga agagcaggat cgctatgcct tgtcgtccca gttgaaagca
    21001 gcacatgctg tcgaagccgg tgtattttct gaggagatca tcccagtcaa gatttctgat
    21061 gaagacgtgt tatctgagga tgaagcagtt cgtggaaata gtacattgga aaaactgggc
    21121 acgttacgta cagtattctc agaagaagga actgtaacag caggaaatgc ttccccgttg
    21181 aatgacggtg cctctgtggt gatccttgca tccaaagaat acgcagaaaa taataatctg
    21241 ccttatttag caaccatcaa agaagtagcg gaggtcggta ttgacccaag tatcatggga
    21301 atcgctccaa tcaaagccat tcaaaaattg acagatagat caggaatgaa tttatcaaca
    21361 atcgatcttt ttgagatcaa tgaagcattt gcagcttctt ctatcgtagt tagccaagaa
    21421 ctgcagttag atgaagaaaa ggtcaatata tatggaggag caatcgcatt aggccatcca
    21481 attggtgcaa gcggtgcacg tatcttgact acattagctt acggattgct tcgtgaacag
    21541 aagagatacg gtattgcttc attatgtatt ggtggaggtt taggcttggc agtcttgtta
    21601 gaagcgaata tggagcaaac acataaggat gtgcaaaaaa aaaagtttta tcagcttacg
    21661 ccatctgaac ggcgcagtca attaatagaa aaaaatgtat tgacacaaga aactgcgttg
    21721 atttttcagg aacaaacact ttctgaagag ctctccgatc acatgatcga aaaccaagtg
    21781 agtgaagtgg aaatcccaat ggggatcgcg cagaattttc aaatcaatgg caagaaaaaa
    21841 tggattccga tggcaacaga ggaaccatct gtcattgcag ctgcaagtaa tggtgcaaaa
    21901 atctgtggaa atatctgcgc agaaacacct cagcggctga tgcgagggca aatcgttcta
    21961 tcaggaaaat cggagtatca agcagtgatc aatgcagtta atcatcgaaa agaagagctg
    22021 attctttgtg caaatgaaag ttatccttca atcgtgaaac gcgggggcgg tgttcaagat
    22081 atctctactc gggaattcat ggggagtttc catgcatact tatctattga ttttttagtg
    22141 gatgtaaaag atgcaatggg cgctaacatg atcaactcga ttcttgagag tgtggcaaac
    22201 aagttacggg agtggttccc tgaagaagag attctattca gtattttaag taattttgct
    22261 acagaatcat tggcttctgc ctgttgtgaa atcccattcg aacgcttagg gagaaacaaa
    22321 gaaatcggtg aacaaattgc caaaaaaatc caacaggcag gggaatatgc gaagcttgac
    22381 ccttaccgtg cagcaacgca caacaaaggg atcatgaatg gtatagaagc tgtagtggca
    22441 gctacaggaa atgatacacg tgcggttagc gcttcgatcc acgcctacgc ggcaagaaat
    22501 ggattatacc aaggattaac agactggcag atcaaagggg ataaactagt tggaaaacta
    22561 acggtgcctt tggctgttgc cacagtaggc ggagcttcca atatcctgcc aaaagcaaaa
    22621 gcatctttag ctatgttaga tattgattca gccaaggaac tagcacaagt aattgctgca
    22681 gtagggttag ctcaaaacct ggctgctttg cgtgcattag ttacagaagg aatccaaaaa
    22741 ggccacatgg gacttcaagc tcgttcatta gcgatctcaa ttggggctat tggtgaggaa
    22801 atcgagcaag ttgcgaaaaa attacgtgaa gcagaaaaga tgaaccagca gacagctata
    22861 caaatattgg aaaaaatccg ggaaaaataa aaaagcaata tctttagaag aataaagcaa
    22921 gatttacagt tattttattt actgcagatc ttgctttttt ggctcttcgt caaattgtgt
    22981 tggcgaagac aaatttgaat aaaacttagt ccgatatgcg gcgcgttctg tgcgccgcat
    23041 atttttttag ttttcaaaga tcagaccttg ttgtaaatag atccgtgccc gaaagttata
    23101 aaagttgcga
//
LOCUS       DAFLWC010000045        22886 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.046, whole genome shotgun sequence.
ACCESSION   DAFLWC010000045 DAFLWC010000000
VERSION     DAFLWC010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22886
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.046"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            30..584
                     /locus_tag="L1V17_001614"
     CDS             30..584
                     /locus_tag="L1V17_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1236387.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
     gene            complement(757..1230)
                     /locus_tag="L1V17_001615"
     CDS             complement(757..1230)
                     /locus_tag="L1V17_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1236388.1"
                     /translation="MRIKPIKDGEQLLFSSEENKPLYLDYVNHNLKIIIKENNLKHIT
                     LHGFRHTHCSLLFESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFM
                     SSTEEKQGSLQKVKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            1242..1778
                     /locus_tag="L1V17_001616"
     CDS             1242..1778
                     /locus_tag="L1V17_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBN1236389.1"
                     /translation="MPARIHHISIVNRFIRPTFDFYHNILGLKLLMKTINQDDHTMYH
                     LFFSDNHHRVGTELTFFEVQEGNNQFFGTNTIERTILKVPSEASLHFWEIYFETQGVC
                     HYGIESFSGRPILRFEGPDATRLALVPLREFEDIDDYFPYVTDQIPTEHAILGIDAIQ
                     LRVQYSDATERELLSVGW"
     gene            1818..2189
                     /locus_tag="L1V17_001617"
     CDS             1818..2189
                     /locus_tag="L1V17_001617"
                     /inference="COORDINATES: protein motif:HMM:NF013098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBN1236390.1"
                     /translation="MTILENQDTQFYQEVQIIQDRENPVAIEGIGSVHHVAFGVENKS
                     DLQRIDKQLQERNFINSGIKDREFFVSLYYRDPNQLLIEIATGEGNLDAKAYENQSPR
                     FEEIPLFLPQYLNFIREQVEQ"
     gene            2473..3744
                     /locus_tag="L1V17_001618"
     CDS             2473..3744
                     /locus_tag="L1V17_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBN1236391.1"
                     /translation="MKLSTQEKQLKNVSLKIPKNKISIFTSVSGSGKSSIVFDTITQE
                     AGRQLNDTYDSFTRLFLPKYSRPEVDEIDNLSTAIVVNQKKIGGSARSTLGTITNINA
                     LFRVLFSCFATPSLGYANAYSFNDPSGMCSVCQGIGKTIAFLIGLLYFSAIDNADFVF
                     SDPFTAEVLSGIEEQAKNHGYFVLVHNVNSAEDVKTIQRNWRFEGFIVVGVRVKEFLE
                     LNNVFDGPVVYIDTHLSKETLRELEQQMNRLFVNTNDYQASTLAVEHLIHYGHEKIAF
                     LSFDYIVGEPSVIQERHQAYIDTLKKYHLTFKSHWIYNNSEFERIYQELAEFTAIVVT
                     GDYLAAKLVKFLKNKNKRVMEQLSIIGFDDITFAELMDPALTTIRLNPGNKGAIAFHQ
                     LIGLAKQEEIKNQVLLLEGELISRDSVHKIK"
     gene            3989..5014
                     /locus_tag="L1V17_001619"
     CDS             3989..5014
                     /locus_tag="L1V17_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1236392.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            5308..6417
                     /locus_tag="L1V17_001620"
     CDS             5308..6417
                     /locus_tag="L1V17_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBN1236393.1"
                     /translation="MLDEFEKQNPDIKVEMETTPWDQYWVKLEAATTGGNMPDVVTMH
                     SSESYKYMSQNALMGLDDVIKENDIDMGNFTEGIADFYTLEDELYAIPKDASVVGLWY
                     NKELFDNAGVDYPDETWTWETLRQAAIDLTDESKGIYGFASHIGTETGYWPFIYQNGG
                     EVFADDNTKSGLNTPEAQEALAFYRDIALVDHASPTITELQDPDKLSRFQSGRLAMMI
                     EGNWFAPGFLKNDYLVENVASAVLPKGKVNATITNGLGWAASASTKYPEEVKKLMAFL
                     ASEDANKIQAETGASIPALKGFEDEWAASSDTIDLSAFGKMLEYGVPRPYNKDGLRAE
                     QAEVQIINRILSGEVTVEDGTAQIEKEVNAILSGN"
     gene            6500..7396
                     /locus_tag="L1V17_001621"
                     /pseudo
     CDS             6500..7396
                     /locus_tag="L1V17_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648409.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            7412..8236
                     /locus_tag="L1V17_001622"
     CDS             7412..8236
                     /locus_tag="L1V17_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1236394.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            8268..9578
                     /locus_tag="L1V17_001623"
     CDS             8268..9578
                     /locus_tag="L1V17_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HBN1236395.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            9726..10985
                     /locus_tag="L1V17_001624"
     CDS             9726..10985
                     /locus_tag="L1V17_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBN1236396.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            10995..11867
                     /locus_tag="L1V17_001625"
     CDS             10995..11867
                     /locus_tag="L1V17_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1236397.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            11879..12709
                     /locus_tag="L1V17_001626"
     CDS             11879..12709
                     /locus_tag="L1V17_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1236398.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            12749..14932
                     /locus_tag="L1V17_001627"
     CDS             12749..14932
                     /locus_tag="L1V17_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBN1236399.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            14993..16213
                     /locus_tag="L1V17_001628"
     CDS             14993..16213
                     /locus_tag="L1V17_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligo-1,6-glucosidase"
                     /protein_id="HBN1236400.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            16210..17670
                     /gene="gtfA"
                     /locus_tag="L1V17_001629"
     CDS             16210..17670
                     /gene="gtfA"
                     /locus_tag="L1V17_001629"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HBN1236401.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            17747..18853
                     /locus_tag="L1V17_001630"
                     /pseudo
     CDS             17747..18853
                     /locus_tag="L1V17_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            19175..19384
                     /locus_tag="L1V17_001631"
     CDS             19175..19384
                     /locus_tag="L1V17_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBN1236402.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMASKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            19377..19526
                     /locus_tag="L1V17_001632"
     CDS             19377..19526
                     /locus_tag="L1V17_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HBN1236403.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            19680..20345
                     /locus_tag="L1V17_001633"
     CDS             19680..20345
                     /locus_tag="L1V17_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1236404.1"
                     /translation="MELREIRPIDIQKWQNNLLSKYKNSYVRNMYGIFQMSLDRAVVL
                     GLLEKNPAKVIGNVKKRKTTVDFWTKEEFTKVISTFYIDDLYQHFGFICMWLLFMTVM
                     RLGEATALTWKDIDFENKNLRVNKTLYYKRAKTYEFVEPETASSIRTIELDDNTITFL
                     KAWKERQVSIGGMSFVLSYNGTPTQKYTIRHIMRRHATIVGVHIIRIHGLRHSHASLL
                     ISQ"
     gene            complement(20629..21714)
                     /gene="xerS"
                     /locus_tag="L1V17_001634"
     CDS             complement(20629..21714)
                     /gene="xerS"
                     /locus_tag="L1V17_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HBN1236405.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            22048..22281
                     /locus_tag="L1V17_001635"
     CDS             22048..22281
                     /locus_tag="L1V17_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HBN1236406.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            22278..22685
                     /locus_tag="L1V17_001636"
     CDS             22278..22685
                     /locus_tag="L1V17_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBN1236407.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
BASE COUNT         7816 a         3431 c         4386 g         7253 t
ORIGIN      
        1 tcagaatatt tttaagaagg gaaacaatag tgagctataa tgtacaaccg ttaaggacaa
       61 atgaagagat acaagatttt cagttttggc taagaagaac aagtaatccg gaaagagata
      121 gttttttatt tttgtttgga atcaataatg ggttacgtat gtcagatatt ataggattaa
      181 aagttggaga tatacgaggc aaaagtaagc ctattattgt tgaacataaa acaggtaagc
      241 gaaaaccgat ttttatagat aatttgagag aagaaatttt attatatact gaaggtaaag
      301 aagaaaatga ttggttattt ccgagtcggc aacaaggtcg acatataaca agggatcgtg
      361 tctatcagat atatgcagat atagcagaaa aattaggacg agatgatata ggaacacata
      421 cattaagaaa aacttttggg tatcactact acaagaaaac tagagacatt gctaccttaa
      481 tgtttatttt taatcatagc tcgcaagcaa ttacaaaaag gtacattggt ataactgaag
      541 atgaaatagg agcatcactt cgtggattta aactaggtgt ataatttaaa aatttttata
      601 aacagtaaag acaaagatta aaagctattt ttatctagaa cgattttatt tcataaagtt
      661 cgcggaataa aagctggggt tactggtact tggtataggt tcgtgttata taaactaagt
      721 aattaaataa catttttagg ttggaaaagg atgaaattaa aaaaagagaa tcaatacggt
      781 ctcaaaaacg caaacgctgc ggaataagaa aaatactgat aactcaacgt ttagcagact
      841 atctaatagg gatagtctgc ttttttcgtt tttgaccata cttttgacct tctgcaaact
      901 tccttgcttt tcctctgtag aactcatgaa atctgcaaaa cgaattgccg tttcctctgt
      961 ctgctttttc gcgatatggg tgtatatatc atccatagtg gttttaatat ctgtatgtcc
     1021 aagtcgaaca tacacttctt tgacagacgc accagattca aagagcagac tacaatgggt
     1081 atgacgaaaa ccatgaagtg tgatatgttt taagttattc tctttaatga tgattttcaa
     1141 attgtgattt acatagtcta aataaagggg cttattttct tctgatgaaa acaaaagttg
     1201 ttcaccatct tttataggtt tgattctcat ttttagatat tatgcccgca cgtattcatc
     1261 acatttctat tgtgaatcgc tttattcgac cgacatttga cttttatcat aatatactcg
     1321 gtttaaaatt actaatgaaa acaattaatc aagacgatca taccatgtat cacctgtttt
     1381 tttcagataa tcaccaccgt gtgggaactg aactgacttt ttttgaagta caagaaggga
     1441 acaaccagtt ttttggaacc aatacgattg aacgaacgat actaaaagtt ccttccgaag
     1501 catcattgca tttttgggaa atatattttg aaacacaagg cgtttgccat tatggaatcg
     1561 aatcattttc tggacgacct atcttacgtt ttgaagggcc agatgcaaca cgattagctt
     1621 tagttccctt acgcgaattt gaagatattg atgattattt cccgtatgtc acagaccaga
     1681 tccctacaga gcatgccatt ttaggaattg atgccattca actacgcgta caatattccg
     1741 atgcgactga acgagagtta ttgtcggtag gctggtagca caaagaatac gtcagtttct
     1801 tttcgggtca tcaacgagtg acaatcttag aaaatcaaga cactcagttc tatcaagaag
     1861 ttcagattat tcaagatcgt gagaatccag ttgccattga agggattggt agcgtccatc
     1921 atgttgcgtt tggcgtagaa aataaatctg atttacaacg catcgacaaa caattacaag
     1981 agcgcaattt tataaattca ggaataaaag atcgtgaatt ttttgtatca ctttattatc
     2041 gtgacccaaa tcaattattg attgaaattg ctacagggga aggaaaccta gatgcaaaag
     2101 cgtatgaaaa tcaaagtcca cgctttgaag aaattccttt atttttaccg cagtacttaa
     2161 atttcattcg tgaacaagtg gagcaataat tagctaatca aatccatgac gaagagtaag
     2221 aggttgactc ataagtcaaa aaataaagaa aaacgcatca aatccattct aaagaatgtt
     2281 gatttgatgc ggttcctatt tttataaact atcattttcg actaataaaa ctacttatga
     2341 gtcagcctct ctttttttct tgatttttat acctctttct aggtaaacta aacatctgcc
     2401 aaaaataccg tgtctcattg aaacattctc aactatttca aaataaaggg gagtaccaaa
     2461 tgaacgagta tattgaaatt atccacgcaa gagaaacaac ttaaaaatgt cagtctcaaa
     2521 attcccaaaa ataaaattag tatttttacc agcgtatctg gttcaggaaa atcatcgatt
     2581 gtttttgata ctattaccca agaagctggt cgtcaactga atgacaccta tgatagtttt
     2641 acccgtttat ttttacctaa atacagtcgt ccagaggttg atgagattga taatctttct
     2701 acggcgattg tggtcaatca aaagaagatt ggtggcagtg cgcgctcaac gttagggacg
     2761 attactaaca tcaatgcgtt atttcgtgtg ttgttttcat gttttgcaac acctagttta
     2821 ggatatgcaa atgcttattc atttaatgat cctagtggaa tgtgttctgt ctgtcaggga
     2881 atcggtaaga cgattgcatt tttaatagga ttgctttatt tttcggctat tgataatgct
     2941 gattttgtat tttctgatcc atttaccgca gaagttttgt ctggaattga ggaacaggca
     3001 aagaatcatg gttattttgt attggtgcat aatgttaatt cagcagaaga tgttaaaact
     3061 attcagagaa attggcgttt tgaggggttc attgttgttg gtgtacgtgt aaaagaattt
     3121 ttggaattaa ataacgtttt tgatggtcct gttgtttata ttgatacgca tctttcaaaa
     3181 gagacattaa gagaacttga acaacaaatg aatcgtttat ttgtaaatac aaatgattac
     3241 caagctagta cattggcagt ggaacatttg attcattatg gtcatgagaa aatagcgttt
     3301 ctttcttttg actacattgt aggtgaacca agtgttattc aagaacgaca tcaagcttat
     3361 atcgatacat taaagaaata tcatttaacc tttaaatcgc attggatata taacaactct
     3421 gaatttgagc gaatttatca agaattagct gaatttactg caattgttgt tactggagat
     3481 tatttagcgg ctaaattagt aaaattttta aaaaataaga ataaacgagt gatggaacaa
     3541 ttatcgatta ttggatttga tgatattact tttgcagaat taatggatcc tgcgttgaca
     3601 acaatacgac taaatccagg taacaagggg gcgattgctt ttcaccaact gattggactg
     3661 gccaaacaag aagaaataaa aaatcaagta ctactattag agggagaatt gatttctcga
     3721 gactctgttc acaaaatcaa ataaaaaagc tctgtgaaat aagtatagtt aacaataaaa
     3781 tatccgaacg atagagagaa tgaactgtga tctagcagtt cctcgtcgca aattcactag
     3841 aattagcatt atttactcta aattgttcgg atattttttc ttgtttttaa ttatgattac
     3901 agtgcctatt tttaacgaaa tttgcttatt ttcaaaatgt atgattatat gttagtaaac
     3961 actttcaaat atgaaaagag gagctattat ggtaggaatt agggatgttg caaaacgggc
     4021 gggtgtgtcc attgcaacag tatcgcgcgt gctaaatgag gatccgacac tttcagtaac
     4081 cgatgaaacc aaacgaaaga ttgcagaatc ggttaatttt tatcattatg tcaaaaaaag
     4141 tcccgttgca aaaaatttaa caaatattgc attaataacg acagtttctg aagtagatga
     4201 gttggaagat ccctattttc gaacgattcg cagagggatt caagtcgaag cagaacaaag
     4261 caaagtcaat ttgaagaaaa ttattcgttt gtcagaaaca ccgttggagc aagacgattt
     4321 gctaaaatgt caaggtgtgt tgattattgg gcaggtgcta tcttctgtga ttgaagaagt
     4381 atcagcaatt aattcgaatg tcgtagtgat tgatgaccct agtattgaag ctgaagtaga
     4441 tgcagtttat actgatttaa caaaagcaac gaatcagcat ttagatcgat tgtataaaaa
     4501 aggacaccga aacattgcgt ttatcggagg aggacgtgtt cgtttagata gccaaggaaa
     4561 taaacacgtg tcagatgatg attatcgaaa aatagcctat gagacgtgga tgaaacaaaa
     4621 aggattagaa aaatatagtc aaatttattt agaaggctgg accacacttg acggaatgca
     4681 ggcagcagat ttacttttga aaaaacatgc taaagataag ttgccgactg ctatcatggt
     4741 aggaaatgat cctattgctg tgggggttta tcgttcactt caaaaaaatg gtctacatat
     4801 tccagaagat atttcgattg tgagttttga taatattgaa gttgctgaat ttttaacacc
     4861 tgcattaaat acggtgaatg tgaatacaga agaaattgga aaactagcag ttcgcatggt
     4921 taatgaacga ataaaagaag ttagaaatgt ttcgatcaaa gtgattgttt ctaataatat
     4981 tattgttaga gaaagtgaaa aaaatatcga ttaaaaaagt aaacatccaa aaaagggtgt
     5041 ttactttttt gtttactaat atttttagta aaaaatctcg acaaaacatt aagtaaacag
     5101 ttatggtgtt gttaacaaaa agaaaacgca ttcaaaacag gaggaattaa gatgaaacat
     5161 ttcaaaaaaa tagctttaac agggatagct gttttaactg ggacattact cgcagcatgt
     5221 ggtgggggag atagtaattc taaagacggg caagtaactt taagctatgc gagttgagat
     5281 actgaccaag ctccaggact aagaaaaatg ttagatgaat ttgaaaaaca aaatcctgat
     5341 atcaaagtag aaatggagac aacgccttgg gatcaatatt gggttaaatt agaagctgca
     5401 acaacgggag gtaatatgcc agatgtagta accatgcact ctagcgaatc ctataaatat
     5461 atgtcacaga atgctttgat gggacttgat gatgttatca aagaaaatga tattgacatg
     5521 ggaaacttta ctgaaggaat tgctgatttc tatacgcttg aagacgaact atacgcaatc
     5581 cctaaagatg cttctgtagt ggggctatgg tacaacaaag aattatttga taatgcaggt
     5641 gtcgattatc cagatgaaac atggacatgg gaaacactca gacaagctgc aattgattta
     5701 acagatgaat caaaaggcat ctatggtttt gcatcacata ttggaacaga gactggctac
     5761 tggccattta tttatcaaaa tgggggagaa gtatttgccg atgacaatac aaaatcaggt
     5821 ttgaataccc cagaagcaca agaagcttta gctttttatc gagatattgc acttgttgat
     5881 catgcttcac caacaattac agaattacaa gatcctgata agttaagtcg ttttcaatca
     5941 ggtagattag caatgatgat tgaaggaaac tggtttgcac cgggattttt gaaaaatgac
     6001 tatctagttg aaaatgttgc ttctgccgtg ttacctaagg gaaaagttaa tgcaacaatt
     6061 acaaatggac ttggttgggc tgccagtgcg agtacaaaat acccagaaga agtgaaaaaa
     6121 ctaatggcat ttttagctag tgaggacgcc aataaaatcc aagcggaaac gggggcatca
     6181 atcccagcac taaaaggctt tgaagacgag tgggctgctt cttcagatac aattgatttg
     6241 agtgcttttg gaaaaatgtt ggagtatgga gtccctcgtc catacaataa agatggatta
     6301 cgagctgaac aagcagaagt tcaaattatt aaccgtattc tgtctggtga agtaactgtt
     6361 gaagatggaa ccgctcaaat tgaaaaagaa gtcaatgcga tattgagcgg aaattaaatt
     6421 agttaattat acaatataca ggcgaaagga ttctatttcg tctgtatatt aatggatgaa
     6481 taccaaaaag ggggatatta tgaaaaatcg aatttttgga aaatatcgta aagatcaagt
     6541 gatatggggc tatattttta tttttccaac ggcattagga ttaattttat taaatatatg
     6601 gccagcaatt caaacagcaa ttttaagttt tcaaaaaacg gtagggttcg gtgatactga
     6661 atgggtcgga ttaagaaatt accaaaaaat gtttgcagac ggtgaagttt ttcagtcttt
     6721 attaaacaca ttaatttatg cagtggtttc gatacctagt attgttgtat tatccttgtt
     6781 ggtggcagtt ttaatgaata gaaaagttaa aggattgtcg atttatcgga caatttattt
     6841 tctaccagtc gttgctgcac catccgcagt cgcaatgatt tggcgctgga tgttcaataa
     6901 tgattatgga ctgattaata acatgttggc taaaataggt ctcgatggac cagcatggtt
     6961 aacggatcca tcgattgcga tttattctat tatcattgta ggagtttgga gtgctattgg
     7021 ttataacatg gtgttattac tagccggctt ataagaaatt cctaaagatt attatgaagc
     7081 agcggaaatt gatggtgcta gtccaatcca gcagtttttc aacattacgt taccattagt
     7141 tacaccaaca ttattttttg tagttgtaac aacagttatc aatgctttcc aagtatttga
     7201 tgttattttt atgatgatta ctcctaatag taccgccatg tttaaatcac aatcattagc
     7261 ctatttattc tataaacatt catttatttt aaatgacaag ggatatggtt cggcaatcgt
     7321 tatgttcctt ttagtgatta tattaattat tactgcaatt caaatgaagt tgcagaaaaa
     7381 gtgggtaaac tattaaggag gctatcaaat tatgaaaaat aaattttttt caaatgcgcc
     7441 aatccatatc atgcttattt taggtggtat tgcaatggca ttacctttta tttggatgat
     7501 tttaacttca gggaaaacgt tggttgaatc tacccaaatt ccacctacaa ttttccctga
     7561 gaaatttcag ctaagtaact atcaacaagt acttgattta ttaccattca tggcttttta
     7621 tatcaataca tttttaatgg ttgttggacg agtgattggc tcggttttat tttcagcaat
     7681 ggctgcatat gcttgtgcgc gtctaagttt tccagggaaa aatatccttt tcagcttagt
     7741 acttattcaa atgatgattc ccggttccat ttttattact ccacagtatt tattagcaca
     7801 aaaattgggt attttaaata caattccagc attaatatta ccaggggtag ttagtgcgtt
     7861 tggtacgttt ttattaagac aatttttctt aggtttacct gatgaattgg aggaagcggc
     7921 ctatttagaa ggtgccaata tttggacgat ctttttcaaa attatgttgc cgcttgctaa
     7981 atcaggattg gttgcacttg gaatattcac agcgttgttt gcatttaaag atttaatgtg
     8041 gccattgatt gtcaatactt caattgataa gatgccttta gctccgggat tagcaaactt
     8101 acaaggacaa tatgccacga acttcccaca attaatggca ggttcgttat tagcaatttg
     8161 gccaatagtt gtgatattca tcgttttcca aagaaaattc attgaaggaa ttgctacaac
     8221 aggtagtaaa ttataaaact attaattagt gattggagag taagtacatg acaaaaatta
     8281 catttattgg tgcaggaagt actatttttg caaaaaacgt attaggcgat gcgatgttaa
     8341 ctccaagtct acaagatgca catattgcat tgtacgatat tgatgaaaaa cgactaaaag
     8401 aatcaaattt aatgcttaaa aatattaata aaaattcgaa tgaaaatcgt gctgatattg
     8461 tttcttatta tgatcgcaaa gaagcgttaa gagaggctga ttttgttatc aatgctattc
     8521 aagtgggtgg ttataaacct tcaacagtga ttgattttga tattcctaaa aaatatgggt
     8581 tgcgacaaac tattggtgac accatgggga ttggtgggat ttttagaacc ctacggacac
     8641 taccagtaat gttagacttt gctaaagaaa tggaagaagt ttgtccaaat gcttggttat
     8701 tgaactatac aaatccgatg gcgatgttaa ccatgggtgt tttaaaagcg acgagtatta
     8761 agactgttgg tttatgtcat agcgttcaag tatgcgtacc agaattgttt gagcatttag
     8821 gaatagccga tcaatatgac ttaaatgact ttcaatggaa aattgcaggc attaatcata
     8881 tggcattctt gttggaaatt acaaaaaatg gggaagattt ctatccaaca attcgtcagt
     8941 tagctgcaga aaaaccaaat ccacatccag attctgtacg ttttgaattg ttgaaacgtt
     9001 ttggttacta tattacagaa tcaagtgaac acaatgcaga ataccatcca tactttatta
     9061 aatcaaaata cccagaattg attgacgaat tagggattcc gttggatgaa tacttacgtc
     9121 gttgtgaaca acaaattaat gattgggaaa gcatgcgaga ggacattgta aataatgggg
     9181 agttaacaca tacgagaagc cgtgaatatg cttcatatat catggattct attacgacag
     9241 gaactccgtc agtgattgca ggaaatgtct taaataaagg cttaatcaca aacttaccga
     9301 cagatgtttg tgtggaagta ccttgtttag tcgataaaaa tggcgtgcaa ccaacctatg
     9361 tcggtgaatt gccaacacaa ttagctgctt taaatcggac gaatatcaat gttcaagaac
     9421 tgacagtaga agccgcttta acactagata aatcaaaaat ttatcaagca gcgtatttag
     9481 atccacatct atcatctgaa ttgtctttaa cagatatcaa aaatttagtg gatgatttaa
     9541 tcgaagcaca tggggactat ttacctgaat ataattaaaa agaagctgaa agagtaagga
     9601 attttcaatt ccttactctt ttcttagtta aatttagtaa aaatattgac aaaacactta
     9661 gtaaacagtt acattagtgt taacaaaaag aaaacgcatt caaattgtat aaggaggagc
     9721 ataaaatgaa gtggtctaaa aaaattattt tagcttgtat agcactagga gcaacgatct
     9781 ctttgactgc ttgtggaaaa aatcaggaag atgcaagcgg taaggtagaa atagagtttt
     9841 ttaatcaaaa aaaagaaatg actcaaacga ttcaggagat tgctaaagat tttgaagcaa
     9901 aaaaccctga tattcatgta aaagttgtgg atgtaccgaa tgctggtgaa gtaattaaaa
     9961 cacgtatgct tgcaggcgat gtaccagatg tcattaatct ttatcctcaa agtatagaat
    10021 tgaaagaatg ggcgaaagct ggttatttag aggacttaac cgaagaaccg tatttagaga
    10081 atatcaaaaa tggatatgca caacgttttg ctattgagga tcgtgtatat agcataccat
    10141 taaccgctaa tgtctatggt ttttactata acaaaactgc ttttgaggaa atggggattc
    10201 aagcaccaga aacttgggca gaatttgaaa aaatagtagc tgagattaaa gatcaaaaca
    10261 aagtaccgtt tgcgattgca ggagcagaag gctggacttt aaatggttat caccaactag
    10321 ctatagcgac tgctgctggt ggtgaagagg aagcgaacaa tgtttggcgt ttctcagaag
    10381 ttaatggaat taatgctgaa agcaaagaaa tgcaaaaaga ttttaatcga ttagatttgt
    10441 taagagaacc aaaagctttg caaaacaact ggcaaggtgc cggttataac gatacagtag
    10501 ttacttttac aaaaggtgat gcgttgatta tgccgaatgg ttcatgggca atgccgatga
    10561 ttcattcaca aaatccagat tttgaagtag gaacttttcc ttttccagca gatgaagcag
    10621 gtcaaagtct aacgattggc gcaggagacc tagccttatc agtttctgca acttctcaac
    10681 ataaagaaga agccaaacgt tttgtagaat atatgacaac acctgaagcg atgcagaaat
    10741 attatgatgt agatggtgca ccgtgtgctg ttgagggcgt tatcgagaat actcaggatt
    10801 caccattaag tggtttaact gaacttgctt ttactgatcg tcatttagtt tggttagcca
    10861 aagattggaa tagtgaaaat gatttttata ccttaacaac aaattattta cacaatggca
    10921 atcaaaaagc catgattaac gcattaaatg ctttctttaa tccaatgaaa gctgacggaa
    10981 ggtaggaaaa taaaatgaaa ataaaagaaa ttttaaatcg ttactgggca atcatttttg
    11041 tagcaattcc aattattttg cagatgattt ttttctactt tccaatggtt caaggtgctt
    11101 tttacagttt aactaattgg actggtctga cttataattt tgattttgtg ggtttgaaca
    11161 attataagat tcttttttct gatccgaagt ttatcaaatc gattggcttc actttaattg
    11221 tgacgctttg catgattgct ggacaaattg gttttggtat tttgattgcg cgggcgttga
    11281 acgcaaatat taaagggaaa acattcttta gagcatggtt cttttttcca gcggtcttat
    11341 cgggcgtggt tgtttcttta gtatttaaac aaatttttaa ctatggttta ccaaaaattg
    11401 gtagtatgtt aggcattgaa tttttacaaa ccagtctttt aggaacaaca tggggagcga
    11461 tttttgcagt aatttttgtt ttactttggc aaggaattgc catgccagtc atcattttct
    11521 tagcgggttt tcaaagtatt ccacaagaaa ttattgaagc tgctagaatg gatggggcga
    11581 atgataagca aattttttgg aatattgaaa tcacctactt attaccaagt atttcaatgg
    11641 tatttattat ggcattaaaa ggtggcttaa cagcatttga tcaaattttt gctttaactg
    11701 gtggtggacc aagcgatgcc acaacatctt tggggttact tgtttataat tatgctttta
    11761 aaaacaatca gtttggttat gcgaatgcta ttgctttagt cttatttatc ttaattggga
    11821 ttgtttcact ggcacaatta aaattatcga aaaaatttga aatctaggag gtttcccaat
    11881 gaaaacatca aaagaaaaaa atatttctaa atacttgctt ttattattag ggggcttcat
    11941 gattttagtt cccttagttt caacgctatt cggttcattt aaaacaacac ccgatattat
    12001 gaataatttc tttcgttttc ctaatccagc gactttggaa aatttccgaa gattgttagc
    12061 ggatggaatt ggtcattact tttggaattc ggcaatcatc acaatcattg cagtagttgc
    12121 tgtgacagca attattccta tggctgctta ttcactagca agaaaaatga ctcgtgggaa
    12181 agcatacgga ttgatgtatt tatttttaat tttaggaatt tttgttcctt tccaagtaat
    12241 tatgattccg attaccgtta tgatgagtaa aattggttta gcaaatatgt ggggattaat
    12301 cttactctat ctcacttatg ccgtaccaca gacactattt ttatatgttg gttttattaa
    12361 actaaatgtg cctatcagtc tggatgaggc tgctgaaatt gatggggcta gtcactttac
    12421 aacttatttc aaaattgttt tcccaatgtt aaaaccaatg catgcgacga ctattattct
    12481 taatgctcta tggttttgga atgatttcat gctaccatta ttaattttaa atcgtgattc
    12541 taatatgtgg acactaccat tgtttcaata taattatacg ggacaatatt ttaacgacta
    12601 tggtccaagt tttgcttcct atacagtagg aattgtcacg attacactag tttatcttgc
    12661 tttccaaaga agtattatag ctggaatgag caatggagca gtgaaataac caataaatta
    12721 ttctcattat aaaggagttc ataaacttat gattatattt gacaatcaca cacaaacatt
    12781 tcatttacaa aataaaaaaa ttagctatct attaggaatc gaagaaaata attatttaac
    12841 gcatctttat tttggaaaaa agattacgca ctattctggt gggtatcgct acccccgaac
    12901 agatcgttcc ttctcaccca acaatgcaaa tgcgcaagat cgtttattat ctttagacac
    12961 attaccatta gaatttccag gatatggaca tggtgatttt agagaaccgg cgcataatat
    13021 taaattagga aacggtagtc gtgtaaatga ttttcgttat gatagctacg aaattcaaaa
    13081 aggaaagccc agcttagcgg gattgccagc cttatatacg gaagatgatg atgaagctga
    13141 aacgctgatt attcaattga aagacgcgat tagtggattg actttacagt tgttctacac
    13201 aatttatcaa aatcacagtg taattattcg ttctacgcaa ttagtaaata atagtgatga
    13261 aacagtggag attaaccgct tagctagtca atcaattgat tttccaaatc gtccactcga
    13321 gttaattcat ttaaatggta cctgggcaag agaacgtcaa atgactagag aaaaaattca
    13381 tacagggata aaagtattag atagtaaacg cggatcaagc agccatcaac aaaatccgtt
    13441 tgttgcttta gtagatgcca aaacagatga atttcaagga gaggcatatg gatttaattt
    13501 agtttatagc ggtaatcacg aaacggtgat tcaaaaagat ccatttgacc aaacacgggt
    13561 cattatggga attaattcat ttaattttgg ttggcaacta aaaactggcg actcatttca
    13621 aacgccagaa gtcgtgatgg tttatagtaa tgaaggtctg aatacgttat cacagacgta
    13681 tcatgaattg tataatcacc gtttaattcg tggaaactat cgtttaaaag aacgtcccac
    13741 gttaatcaac aactgggaag caacgtattt tgattttaac gaagaaaaaa tcatgaatat
    13801 tgtcgatgat gcgaagaact tgggcattga aatgtttgtt ttagatgatg gttggtttgg
    13861 cggtcgtgaa aatgacttca cttcattagg tgattgggtt gaaacagaag gcaaacttgc
    13921 ttgtggtttg gaaaatttag ccaagcaagt gcatgataac gggatgaaat ttgggatttg
    13981 gtttgaaccg gaaatgattt ctgaagatag tgaactattt cgagcacatc cagattgggc
    14041 attgggtatt ccaggtcgtg accgctcaat tagtcgaaat caatatgttc ttgatttttc
    14101 aagacaagat gttcgtgata atatctatca acaaatgacg gcgatttttg atcgtgtacc
    14161 gattgattat gtgaagtggg atatgaatcg aaatatgaca gaagtctatt ctgtcttgtt
    14221 ggactcaacg atgcaaggtg aagtggctca tcgttatatg ttagggttat atgaattttt
    14281 agaaaagtta acaacgaatt atccaactat tttatttgaa agttgttcgg gtggaggcgg
    14341 tcgttttgat gcaggtttct tgtattacat gccacaaact tggacgagcg acaataccga
    14401 tgccgtggct cgtctgaaaa ttcaatatgg aaccagctta gtgtatccaa tttcaagtat
    14461 gggtgcgcat gtttcagcag tcccaaatca tcaaacagga agagaaacga gtttaactat
    14521 tcgtggcaat gctgcgatgg ctggtgtttt tggttatgag ctagatctaa cgcaattaac
    14581 ttctgaagaa aaagcagaaa ttaaagaaca agttgccttt tataaaaagc atcgccaact
    14641 tttgcaatat ggaacttttt atcgcttgga aagtccgttt gaaggcaatg atactgcatg
    14701 gatgtttgtc tcaaaagacc aaacagaagc catggtcttt tatttccgag tattagcaga
    14761 agctgcgcat ccattagtca cattgaaatt agcaggatta gcagaagaag caacttatca
    14821 aatggaagat gtaacatttg ctggcgatga attgatgaat ctcggttttt atattgactc
    14881 agaactacat ggtgattatg cgacacaacg cttttatttg aaacagatat agtagcttga
    14941 atttacaata taagtgcaac accaaaagag actcattcca aacgaagaaa atatgtttta
    15001 tttacacgca tttactaaaa agcagcctga tttgaattgg gaaaatgaag aagtacgtga
    15061 agaaatctat gcaatgatta actattggtt agataaagga ctaggcggat ttagaatcga
    15121 tgcgatatta aacatcaaaa aaaaactaga gtatggcatc tttgaatctg atggagaaga
    15181 tgggttagcc ttcattgggc cctggattct taatcagtcg ggcattgaag tgtggttaaa
    15241 agaaatgaga gagcggacat ttaaaccaca taatagtatg acggtagcag aagccgatgt
    15301 tcctaatgaa cgtttagatg aatatattgg tgaagatggc tattattcga tggtttttga
    15361 ttttagttat acggatattg atgtacctga aactggtgaa tggtttaaag atagccaatg
    15421 gacatggacg gatatgcgta ccaatatttt tacgaatcaa ttagttacgc aagataaagg
    15481 ttggggcgcc ttatatttag aaaaccacga tcaaccacgt tcaattaata aatatattcc
    15541 agaagaatgg atcaatgatt atagtaaaaa aatgttggcg acgcttttta tgttactaag
    15601 aggtacccct tttatttatc aaggacaaga actaggaatg accaacatag aaatggcatc
    15661 attagaagat tttgatgatg tagctacgca ttctcagtat aaacgggcat tagaatatgg
    15721 attggcacca gagcaagcat tgaaagctgt caataaacga agtcgggata attctcgcac
    15781 acctatgcaa tggaatacgc aaaaaaatgc cagattctca acttctgata atgtatggtt
    15841 aaaagtaaat cctaattatc cagaactcaa tgcagaagct cagttaacca atcaacagtc
    15901 ggtattcaat tattatcatc aattaattaa attaagaaaa aatagtgtat acaaagacgt
    15961 gctaatctac ggacaatttc taccagtgaa agataaaaat gaacatattt tgctttatga
    16021 acgccaatta gaagataaaa tcgtattagt tatcttaaac gttacagcaa cagaacaaga
    16081 atattatgta gatgaacagt accaacaagt attaatcaat aattatgaag atgttttatt
    16141 agatcaaagt cgaaaattgc gtttacgacc gtttgaaagt attgtattag ctaattatgg
    16201 aggacaatta tgaaaattaa aaacgaagca atgctcatca cctatgcaga tagtttagga
    16261 aaaaacatgg gcgaattaaa acaagtctta gacaaacatt tacaaggtgt tattggtggt
    16321 gtacatctgt tgcctttttt tccatcgaca ggtgatcgag gctttgcgcc gagtgattat
    16381 acgacagttg atccagctct tggaacatgg gaagatgtgg aagcattagg tgaagattat
    16441 tatttgatgt ttgattttat gattaatcac atttctcgtg aatcaaaatt tttccaagat
    16501 ttcaaaaaaa accatgagca gtcaccatac aaagaaatgt ttatccgtat tcatgaattt
    16561 ttcccagaaa atcgaccaac acaagaagat attgatttaa tctacaagcg taaagacaaa
    16621 gcgccgtttc aaacggtaga atttgcggat ggtacgacag aagaggtttg gaataccttt
    16681 ggggaagaac aaattgattt agatgtgacc aaagaagttg tgaaagaatt tattcgagaa
    16741 accatcaaag atatggcgaa ccatggctgt tctttaattc gattagatgc gtttgcttat
    16801 gcgattaaaa aattagatac caatgatttc ttcgtggaac cagatatttg ggaactttta
    16861 gacgaagtgc gtcaagaagc agcgaaatat gacgtcgaat tattaccaga aatccatgag
    16921 cattattcca ttcaaatgaa aattgccaat catgattatt atatctatga cttcgccttg
    16981 ccaatggtca ctctgtattc actttatagt ggaaaatcag aacgtttagc caattggttg
    17041 aaaatgagtc cgatgaagca gtttacaaca ttggatacgc atgatggaat tggtgttgtg
    17101 gacgctcgtg atttattaac agatgaagaa ttggattaca cctctgagga attgtataaa
    17161 gtcggggcga atgtgaagaa ggtctattca agtgccaatt acaataattt agatatttat
    17221 caaattaaca gcacctatta tagtgcatta ggcgataatg accgtagcta tctgttagca
    17281 cgtgcgattc aagtatttgc gccagggatt ccacaaattt attacgttgg gttattagca
    17341 ggaaaaaatg atattgaact gttggaagca acgaaagaag ggcgtaatat taatcgtcat
    17401 tactatgatt tagccgaaat tgaagaagaa gtgcaacggc cagtgattca acaattattt
    17461 gcacttttaa aatttagaaa tgaatctgcg gcgtttgatt tggatggaac gattgaagta
    17521 gcaacgccat cagaatcaga aatagtgatt acacgtaaaa ataaaaacgg tagtgatagt
    17581 gcaacattaa cggctaactt ggatacgaaa gaatttatca ttgagtctaa agatataaaa
    17641 attttcacta gtgttgcatt aaaattttaa cctattccat agaacaaaaa atcctttata
    17701 ctagcacttg gatgacttat ccaagaccaa taaaaaggac tcatacatgg ataagtataa
    17761 aacaaataca gcatttaata aatggttttc tgccataaaa ttaggaaaac tttctgtcaa
    17821 ctcccaaaaa tgtatttttg attacaattc gtatcgtaaa aaactgtctt ttgaagctgt
    17881 gctcaagctc tttctctacg cagttaatga agaaaaagaa agtttgcgtg atttgagtac
    17941 agctcttatc gaccgatcgc tccaactaga aaccgatgtg tcatcgatta gtcataccca
    18001 attgtctcga gcatttaatg cacttgaacc taaagtgtta gaagaaattt ttcaacaact
    18061 gttagaaaaa gttcaacatc aaatcaaacc aaccaagcga aatcatctgt atctgattga
    18121 ttccagtacg ttttcgctta gtttaaaacg tcataagtgg gcgactttcc gtcaaacaaa
    18181 atcaggtgtc aagttacact taaactattg ttatatggac gatactacga tgtatccaac
    18241 tgattttacc ttaacaaatg cccatgaaca tgatctcaat caactaccag tattggtgaa
    18301 tcaaccagag gcaacttacg tgtttgatcg tgggtattag gactttgaaa agatggatca
    18361 gatgcattgg gatggctatt tcttcgtcac tcggattaaa aaaaacacca aagttcacgt
    18421 gatagatact ctggaaacat cgccagaaac agaaattcta cgagacgagc tggttcgttt
    18481 aggatctaaa acctatctaa ccgccaattt ccgactagtc actgttcaag ataagaacgg
    18541 acgtgtgttt caatttatca ccaatcgaat ggacgtctct tcaaaagaaa tctctgatat
    18601 gtatcacgct cgttggcaaa tcgaattgtt tttcaagcac atcaaacaac acatgaccat
    18661 taaaaccttc ttttctcaaa gtgaaaaagg cgtgcagaat caattgattt taacgatgat
    18721 ttccgctctc ctcacgtttc tcatcaaatt ggagacgaaa acggaaaaat cagtgttcca
    18781 aatcaaacga ttctttcgtt atttactgtt tcagcccttt gaatgttgtc tagaaaaatt
    18841 aattcccaca tgagaaaaaa gaaatttggc tcgttacttt tggttttcag ttgaataaca
    18901 gataaaaaat tttctggaaa aagtcatcct ctgcgtcagc acagtttttt ttgacttatt
    18961 ttcagaggaa atagttttca gaatattcta aaatgtttta tgcaacacta gtgatatttt
    19021 ttagaattag atttctaatg tgcatttttt gagtattaag gagcaagtat acaaagattt
    19081 ataaagctga ttaaatttga ataaaaatat gcaggaacgc tactattttt agtagtgttc
    19141 ttttttatat ttgaataaaa aatgtggtgg ttaaatggtg gttataacaa aaaatgaatt
    19201 aatgaaatta ggttatggga agtatcagtc tgagagaatc atacgacagg caaaagcaat
    19261 tatggcttca aaaagctata cctattacga aaatagaaga ttaggactag tacctgttga
    19321 atctgtagaa gaagttttag gtatgaagat agaggtagag gaggattttc agaatcatgg
    19381 ttaattttaa aaaagataaa aatgggaaat atcattttac tgctagtttg ggattcgaca
    19441 aacgaacagg gaaaagagta caaaaaaacg tagaggggtt aaaacagtta aagaagaaaa
    19501 aaagcgtata ccgaacttgt ttctaattat ggaaaagaag cagaaacttc tcaaagtact
    19561 atgttgtttg aggagttttt ttataaatta ttcctacctt attatcaagg gaaagtagaa
    19621 gaaagaacat ataaaaatcg gttatctaca atcaaaaaaa cttttcttat ttctttaaaa
    19681 tggagttaag agaaatacgt ccaattgaca ttcaaaagtg gcaaaataat ttattgagca
    19741 aatataaaaa ttcttatgta agaaacatgt atgggatttt tcagatgtca ttagatcgag
    19801 cagttgtttt gggactactt gaaaaaaatc ctgcaaaagt tattggaaat gtgaagaaaa
    19861 ggaaaactac agttgatttt tggacaaaag aagaatttac aaaagttatt tcaacttttt
    19921 atattgatga tttgtaccaa cattttggtt ttatttgtat gtggttactt tttatgaccg
    19981 ttatgcgttt gggagaagcc actgcattaa cttggaaaga tattgatttt gaaaataaaa
    20041 acttgcgtgt gaataaaaca ctctattata agagagccaa aacctatgag tttgtagaac
    20101 ccgaaacggc ttctagtatt cgtacaatcg aactagacga caatacaatt acctttttaa
    20161 aagcttggaa ggagcgtcaa gtttcaatag gaggcatgtc gtttgtactt tcttataatg
    20221 gaacacctac tcagaaatat acaatccgtc atattatgag aagacatgca acgatcgttg
    20281 gtgttcatat aatccgcata cacggattaa ggcatagtca tgcttctttg cttatatcac
    20341 aataaaaaga tgcacttcga attaaagaaa ggttaaaaca tgctgatgta caaacgactt
    20401 taggaactta tggtcatttg tatctaaatt cattgagaga gataacaaat gatcccacag
    20461 attatatcca aactaatttt tctaaaatca aaccgacacc tatttacgat aataaaaaat
    20521 aaatgataaa caaaagtagg atcacaccaa aagaaacaca ctagaaaaac tataatacag
    20581 gcttttctag cgtgttgttt cttatttccg cctatttata cattatactc ataaagcatt
    20641 taatgcatcg atcgtagccg cattgtctat atgggtatat aaagttgttg tattggtact
    20701 tgaatgtccc aattgttggg cagttaatac caatgaattt gtctgttggt agagtctagt
    20761 agctaatgta tgacgcagtt tgtgagggct gacttgaatt ctaaagcctt ttgaatattt
    20821 tgctaccatc cgttcgattg caataccgga tatacgcttg gcttctcctt ggtaaattgc
    20881 tagaaataaa gctttttcgt tttctgttac tttatatcgt tctttccgaa tagctagata
    20941 attagctaaa tattccattg cgaatgctgc tatattgaca gcatctcttt tatttccttt
    21001 tctagttact accacattat tcttatctaa agataggtca tctaaattaa tatttataac
    21061 ctcggagagt ctcaatccag atcctaaaat cagtgcattg atcgccaggt ctctttctac
    21121 atctcgttga taatagatca aagctcgttt actcaaagta tttttatatt cattggcaat
    21181 ataatctaga taattttgtg tatccttatc tagaaataat tttttctcaa tggcattggc
    21241 acgtgcagct aacgtagttt tatctgtgat ggttgctact tgatccatag gattattgtc
    21301 taagtatggt tttcctagag gattattgga acttttcgaa agatatttaa atagaacctt
    21361 taatgccgtg atatttctat tgatagtaga agtagataga cctaagttat tattatcttt
    21421 gagcttagtt tttgttgtct ctttttttac attttctttt gtgcgacgtt tcaaatgaga
    21481 tttgtacaag tttaggtcat aggcagttaa ctgtcttatc gaggtgatag aagtatcagg
    21541 aacgatagac tcactcagaa gccattcata aaagagctta taatttttta gatattctaa
    21601 agtggttcga ggtgattgat ctttatcctc acgatcttga acaaaatctt ttatataatc
    21661 gggcatatga agtatgattg tatctatttt ttgatatatt tctgtatttt tcatgtcatt
    21721 catcctttca ataagtaggg gagaagagta tctctataat tggactatac caattataga
    21781 atgttttgtc aattggtatg ctctaaaatt tattaatttg tttcaaaaaa agcatataaa
    21841 caggtatacg tttaataatt taaaataaat ggtatacata aatagggaag gaaatagaag
    21901 ggagcaatct aaattttttg aattttctta attaattata tagaaagaac aatctttcta
    21961 tagagttaga catgagaggg actatgcttg atttaaaatc aacaagcgta tatactgtat
    22021 atacaaagaa aaaggaggga gaagactatg gcaattaaag aaagaaaatt tagggaagtg
    22081 gggaactcag tagtattaac tatttcaaag gagtttctta aagaaaatgg gttaaatccc
    22141 ggagatacgg tttttttaga tgaagaaaaa cttcgagcgg caattacaaa aaaacaagcc
    22201 ttatctgatg aaattgattt agcaatatct caagcattaa ctgaatatga tactactttt
    22261 agagagcttg tcgataaatg agtattcatt acctagaagc caaagatatt ataaaaatga
    22321 atgtaatcca aataaaaaaa tactctccta atgaacccct tggtgtaaag gatgcgaatg
    22381 ctttagaaat gtgtgtaggg caacttcgag cctcagcttt tggtgaagag gtttatcctt
    22441 cgatttatga aaaagcagct atcctactta tacaattgat aaagaaacat ccttttcaca
    22501 atgcaaataa acgtactgct ttcttagcta cttttgtctt tttgaaaatc aatggacagc
    22561 ttttagctat tgatcaaaaa gatgctgtaa atttagcggt atatattgct acgtatgata
    22621 aggatttcga tcaactaaaa tatgaagtga tcaacactat aaagacacat acgcagccca
    22681 tttaaggagt tactgtatgt gtctttatag ggttattagc tgctatagcg aaataattga
    22741 agtaaattac aaatagctat aattcaaatc caactatata gaaaacgtaa attttctata
    22801 tagttggatt aagataacga ctatttattt tatcatattt ttactatacc ctatactttt
    22861 acttggtata tttatgaata atcgca
//
LOCUS       DAFLWC010000046        22733 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.047, whole genome shotgun sequence.
ACCESSION   DAFLWC010000046 DAFLWC010000000
VERSION     DAFLWC010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22733
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.047"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(26..1957)
                     /locus_tag="L1V17_001637"
     CDS             complement(26..1957)
                     /locus_tag="L1V17_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1236408.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(1975..2889)
                     /gene="pfkB"
                     /locus_tag="L1V17_001638"
     CDS             complement(1975..2889)
                     /gene="pfkB"
                     /locus_tag="L1V17_001638"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBN1236409.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(2886..3638)
                     /locus_tag="L1V17_001639"
     CDS             complement(2886..3638)
                     /locus_tag="L1V17_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBN1236410.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(3797..4006)
                     /locus_tag="L1V17_001640"
     CDS             complement(3797..4006)
                     /locus_tag="L1V17_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236411.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(4017..5344)
                     /locus_tag="L1V17_001641"
                     /pseudo
     CDS             complement(4017..5344)
                     /locus_tag="L1V17_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            5480..5635
                     /locus_tag="L1V17_001642"
     CDS             5480..5635
                     /locus_tag="L1V17_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236412.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(5709..6296)
                     /locus_tag="L1V17_001643"
     CDS             complement(5709..6296)
                     /locus_tag="L1V17_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBN1236413.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(6379..7629)
                     /gene="clpX"
                     /locus_tag="L1V17_001644"
     CDS             complement(6379..7629)
                     /gene="clpX"
                     /locus_tag="L1V17_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBN1236414.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(7876..9165)
                     /locus_tag="L1V17_001645"
     CDS             complement(7876..9165)
                     /locus_tag="L1V17_001645"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBN1236415.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(9319..10251)
                     /locus_tag="L1V17_001646"
     CDS             complement(9319..10251)
                     /locus_tag="L1V17_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236416.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(10408..11067)
                     /locus_tag="L1V17_001647"
     CDS             complement(10408..11067)
                     /locus_tag="L1V17_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBN1236417.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(11070..12095)
                     /gene="sppA"
                     /locus_tag="L1V17_001648"
     CDS             complement(11070..12095)
                     /gene="sppA"
                     /locus_tag="L1V17_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HBN1236418.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(12108..12398)
                     /locus_tag="L1V17_001649"
     CDS             complement(12108..12398)
                     /locus_tag="L1V17_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236419.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            12807..14612
                     /gene="glmS"
                     /locus_tag="L1V17_001650"
     CDS             12807..14612
                     /gene="glmS"
                     /locus_tag="L1V17_001650"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBN1236420.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(14684..16039)
                     /locus_tag="L1V17_001651"
     CDS             complement(14684..16039)
                     /locus_tag="L1V17_001651"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBN1236421.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(16063..17232)
                     /locus_tag="L1V17_001652"
     CDS             complement(16063..17232)
                     /locus_tag="L1V17_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236422.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(17229..18116)
                     /locus_tag="L1V17_001653"
     CDS             complement(17229..18116)
                     /locus_tag="L1V17_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBN1236423.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(18305..21997)
                     /gene="nifJ"
                     /locus_tag="L1V17_001654"
     CDS             complement(18305..21997)
                     /gene="nifJ"
                     /locus_tag="L1V17_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBN1236424.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            22196..22717
                     /locus_tag="L1V17_001655"
     CDS             22196..22717
                     /locus_tag="L1V17_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBN1236425.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
BASE COUNT         6330 a         4939 c         4044 g         7420 t
ORIGIN      
        1 aaacccagcc tcttcttttt tatttctatg cttctgctac tgcaggagct tttctcaata
       61 aaccataaat cacaccagat acgactgctc cgatagcaat aaacaccaaa tacatgaccg
      121 ggtgactcag taagaataca acgaaaatcc cgccgtgagg agccagtaat ttgattccga
      181 aagctccgac taatccgcca gttaaagcag aaccaataat aaaacttgga atggcacgaa
      241 tcgggtcagc tgctgcaaat ggaatcgatc cttccgtgac aaacgatagt cccatcacga
      301 tgttcgtcaa accagcatct tgatctgttt tgctgaattt attcttaaac aaacgtgtag
      361 caacgaaaat tgccaatgga ggtaccattc ctccagccat aacagaagcc atcacgacac
      421 ttccgccagt tgcaacagtc gtagctaaag ttgctgtacc aaacacataa gcggctttgt
      481 tgattggacc gcctaaatct gccgccatca ttccagctaa taatgcacca agtaaagcag
      541 cattcgaacc actcatactt gtcaagaaac cgttcaatgc atcattgatt gctttcatag
      601 ggacattgac cagcaacatc aagaaaccag taatcagtaa gccaaacact ggataaaaga
      661 ggatcgtttt aattccatcc aatgattttg gtaagttctt gaataattta cgtaaaaata
      721 cgatgacata accagctaag aatccaccaa tcagtgcacc taagaatcct gcaccgcctg
      781 tattagctaa tgcaccagca gcaaatccaa cgatcaaacc agggcggtca ccgatacttg
      841 aagcaataaa tcctgctaat accggcagca tgaaaccaaa tgcagcttgt ccgatttggt
      901 tgaaccagct agcagcttga ttgtaattcc ctagatttga taattgatca tgtggcacgc
      961 caataaattg gtcgatcatg aaagaaagcg caatagcgat tcctccacca ataacgaaag
     1021 gtaacatgtg tgatacgccg ttcatcaaat ctttgtaaat tctttgtccg atagtaccat
     1081 ccgcatttcc ttcttctgaa ctgctttctt ttccatcacc atggaatact ggtgcagtac
     1141 cactaagggc tagattgatc aactcttctg gtttacggat accatcactg acaggacgat
     1201 tgatcagttc ttttccgtca aagcgattca tctctacttt tttgtctgct gcaacgatta
     1261 caccttctgc acgggcgatg tcttcagcag tcaatcggtt tttgattcct tctgaaccgt
     1321 tcgtttcgac tttgatctcc acacccattt ctttcgcttt tttcttcaaa gcatcttctg
     1381 ccatgtaagt gtgagcgatc cctgttggac aagctgtaac ggcaacaacg aattttcttt
     1441 ctggatgagc agaagcttct gcagcttgtg tttcttgttc tgctttttct tctgcttctt
     1501 tttgctcttc agctgtttgg aacaagtctt ggacttcttc tggtgtattt gcttctttta
     1561 attttcctac gaaatctgca tcaatcagca atcgagatag tgctgctaat gcttgcaaat
     1621 gtgtgtcgtt tgcgccttct ggagctgcga tcatgaaaaa cagataagtt ggctgtccgt
     1681 ctaaggcttc ataatctact cctttttggc tttttgcgaa taaaactgtt gcttctttaa
     1741 ctgcactgtt tttcgcgtga ggcatggcga ttccatcacc aagacctgta gaagtttgtg
     1801 cttcgcgggc tagaattcct tctttatatg tttcgatatc ggaaatccgg ccggcatcaa
     1861 acattttttg gaccatttca tcgattgcgc cttttttatc agtcgcttgc aaatccatga
     1921 tcatcgcttc tttgaccatt aaatccttga tattcatgat tatcctcctt gaaactaatc
     1981 aatttttgtg atttcaactt ctggcagcaa ctcatcaatc aattcgcgag ctgccaagtc
     2041 atcagaaaaa gctgttgcgc ttccgcaagc aactccccat ttaaaggctt cgattggatc
     2101 tttcgtacgg ctgtaagccc caataaagcc agcaatcatt gaatcccctg cacctactga
     2161 atttttcaat gggcgaacta atacattcgt tttataagtt ccttgttccg tgaagagcaa
     2221 agcaccgtct ccagccattg agatcagcac attctgtgcc ccttcagcta gtaatttttt
     2281 cccatacgga atgatttctt ctacagattg gaaggttgtg ttgtaaagct cagctaattc
     2341 gtgattgttt ggtttgatca acaacggttt cttaacaagt gcatttttta ggtcatcacc
     2401 tgttgtatca atcacgaaat ctgcaccttt ttctcgaatg atatcaatca gttcttgata
     2461 aaatcctttt cgcaggctag ctggcgcgct tcctgacaat acgacgatat ctccttgtcc
     2521 tactgttcct aatgcttgct tcaactcatc gatttcttca tctgaaatag atgggcctaa
     2581 gccattgatc tcagtttcag tgtctgattt tagtttgata ttgattcttg tatcttcttt
     2641 tacggttgtg aacaaagact ggatttgttc tttttcaagc cacttcgaaa taaattcgcc
     2701 agtgaaccct cctaaaaacc ctagtgctgt agattgagaa tcgatccgtt tcaaaatacg
     2761 ggaaacattg atcccttttc ctccaggtaa cttgaagtct tccttcattc ggttcaaatc
     2821 gcctagtttt aacccatcta cgcgtacgat ataatcaatt gatggattaa gtgttactgt
     2881 gtaaatcatt gtattgcctc cttaattgtt gtcttttcac ggaattcatt aacgaattct
     2941 aatggacaac gctcggttat gatcgtggct gcttccaaag gtgcaacaga ggtgaaggac
     3001 aactggttga atttggtatg atcaatcaat acaaatgtct cttcggaatt tttcatggct
     3061 aaacgtttaa cagctgcctc ttctggatcc ggagtcgtga atccttgttc aagatgggca
     3121 ccgttcattc ccataaatgc tttattaaaa tgaaaatttt ttagttgttc tatcgcatta
     3181 gatcctaaaa cagcattagt tgccagcttt atcgttccac ctaaaataat ggtagcaagc
     3241 tccaaatcaa ctaaatttgc cgcatgttga acggaatttg tcactactgt gatctgtttt
     3301 ccttgcagaa aaggaatcat ttctaacgta gtagagccag cgtctaaata aatgacatct
     3361 tcgtcattaa tggtttcagc tgccgatttg gcgatttgct gtttttcgtg aacgtttttg
     3421 agtgattttt cactcatatt ctgctcaaaa ttcaataatt gctctttctt agctccgcca
     3481 tgaactcttt ctagaaaccc actattctcc agctcttgta aatcacgtct tatcgttgat
     3541 tcagaagcat tcaaaaggtt tacaagatct tgtgatttca cgattttctg ctgttcaagc
     3601 aagtctagga ttttttgtct gcgttcctct gtaagcattt tcacgatcac ctcaatacaa
     3661 ataatagcat attttttttc tactagcaat ataaatcagt caaaaacgtt cataaaaatt
     3721 ataaatcagt caaaaaaaaa taaaaaacca gtcagaaaga ctggtttttt atttttttgt
     3781 ctatcatcaa gccgttttat cgttttttat tttcgcttct tgtttttttc atataaacag
     3841 aagcaggttt tctttcctta tgaagaagat aataataaag tcccatcccg ccaaacatga
     3901 ccaaaaaacc gatgactgat cgaataggaa aattaggaac aaaaaagaga cagacggata
     3961 ataatgatgc cggaaccatt attcgataat agagttgttt atccattttc ttcacctcat
     4021 attttttgta aagtaatcaa ttgttctaat tctcggtaat ctaaaaattg cacacgcaga
     4081 tgctgctcac ctttcttgac atcgaattgg atacttcgcc gctttttctt tattcgtttg
     4141 aaggtaacat cagagagtct atgtttgatt tcctttaacg gtaattctga cagggattct
     4201 gaaggaacat agattcttaa ggataaaaga tactcttgat atttttcatc tgttacctct
     4261 acttctagat attccctaat ataataacaa taagcttcga ttccattatc caaagcaaca
     4321 gtcggatcga taactttata gcacatcatg cgtgatcgat tctcgtcaac ccaaggaaaa
     4381 tacgcctgag catttagtgt tccgcgaaca cgcctttctt tataatctcc ttgttggata
     4441 tcataacttt ttgttacaaa aaatgaagca ttctttttag gaacaggttg catttgtgca
     4501 ttctgatact ggacagattg gatcgtatgg tcagtgtaaa tgtattcaac gaatggcggt
     4561 ttcaataaac cgacaccatt gtcccaagca agatgatcaa acccaagctg gtccctaaaa
     4621 taggattgaa acatttgatt gtttggcttt tgccagttaa aggggtctcg ataaagctgg
     4681 atacatatga cttcgttttc taattccttc actttttcta cttgttggat gtcgagaaaa
     4741 atcggtttag ggatgatttg atgataatag cgactataat acatttccca acacgaagtg
     4801 aaacataaac cttggtaaaa aagatcgtat cctggaaatt ggttgcaatc gactactact
     4861 tccccgtttt gttgtttcat tttaggtaaa tgttcgattt catccttttt ctcaaacaat
     4921 agccgttgag agatctgttt tgtattgtga tagataaact cgctataagc tcgcatatag
     4981 gcgaacaccc catgagcaat catttttttc tgaatgaagt ctcgaatcaa aaattgcttt
     5041 tctttgaaaa cagagataga caatacattt tttatcaata attgattatc ttccaagcga
     5101 aaactacatt cgttctcgtc atttcctaca actaaccaac tttcgtctct taccgatgct
     5161 agcattattt tttcttgaag ctttcgaaga tcatacggat ccgcttgttg tgtgaaagag
     5221 cggataaatg ttggctggat caacagacgt gtcaaaatag cccaatcgct tatttcctgt
     5281 ttttttcttc ttcatttaag tctgtgagct ggatagtcat caataattta tcttcgccaa
     5341 tcattttctc acctctttca aatcttttta taatttaatt ataaccaatg ataaagaaaa
     5401 actaaaactt tatgtcttag aaaccaattt ggacgattac atgatagact aagtaaaaag
     5461 aaacaaagag gtgtttacaa tggggttgaa atttgaacgt acagataatt tagataaact
     5521 tttcgaatca tttgctgtcg atccggaaaa aacagttgca ccaaaagaag agatcgatcg
     5581 atttctaaaa ccacagccac aaaatgaaaa gaaaaaagac aagaaacaaa agtaagttaa
     5641 gctcaaaaaa agacttacca gccaaacttt tatgaaagag tttgactggt aagtcttttt
     5701 tattcttttt atgattcaat tgcttgttcg attgctgccc acgcttcttc ttttccctgt
     5761 tttgtaacgg aagaaaagag aataaacgtg tcattgcgat caaaatccaa cgcttttttg
     5821 atttcgctct catgcttgtt ccatttacca cgagggatct tatctgcctt agtggcaaca
     5881 acaattacag ggatatcata atacttcaaa aattgataca tctggatatc ttcttgagaa
     5941 ggcttatgac gcaaatctac taaagaaacg accgcacgta gctggtctct agtcgttaaa
     6001 tatgtctcga tcatctttcc ccattttgct cgctcagttt tggatacttt tgcataccca
     6061 tatcccggaa catcgacaaa atgtaatgcg ttctcgatca aataaaaatt caatgtctgg
     6121 gtctttcctg gcttaccgga agtacgggct aaattctttc gatcaatcaa tgtgttgata
     6181 aaagaagatt tccctacatt tgatcgtcct gccagagcta tttctggcaa ttgtgtatct
     6241 ggatattgtt ttggtgccac tgcacttatg ataatttcag cttgatggac tttcatggtc
     6301 tctctcctta acaaggtgat gaataaagca agcggctgtc gcaaaagcca aaatgacttt
     6361 tacggcagcc tcttttcatc aacccgcttt tttctctgaa tctttataga ttactgttgg
     6421 ctcaccagac aattcagctg cttcttttgt gataatcact ttttcgatgt tttcatttga
     6481 agggatatca aacatcacat ccatcatgat ttcttcaatg atggaacgaa gtcctcgagc
     6541 accggtattg cgttcgattg cttttttcgc aatggctctc aacgcttcag gttcgaattc
     6601 aagttcggta ttatctagag aaagaagttt ttgatattgt ttgactagcg catttttcgg
     6661 ctcagtcaag atccgtacca gatcatctgt tgtcaatttc tctaaagctg ccataacagg
     6721 taatcgtccg ataaactcag ggatcaatcc gaattttagt aaatcttcag gaatgatatg
     6781 ctgcatgaca ctttcgtctt cagaaagttt ttggttttgt gtaccaaatc caatcgtctt
     6841 ttcgcccata cgattcttca caatcgtttc gatgccatca aatgcaccac ctacgatgaa
     6901 caatatgttc gtcgtatcaa tctgaataaa ttcttgatgt ggatgtttac gtccgccctg
     6961 aggtggcaca cttgcaacag ttccttctag aattttcagc aaggcttgtt ggacaccttc
     7021 gccggaaacg tcacgagtaa tagatacatt ttcgctttta cgcgcaattt tatcgatctc
     7081 atcaatatag atgatccctt tttctgcaag ttccacattg taatcagcag attgaagcaa
     7141 tttaagcaaa atgttttcta catcttcccc cacataacca gcttctgtca aacttgtcgc
     7201 atctgcgatt gcaaaaggta cattcaatgt ttttgctaat gtttgtgcta aaaatgtttt
     7261 accagaccct gtaggtccga tcaagcagat attgcttttt tgcagttcaa catcatctgt
     7321 gttttcttgt gcttgctgat tgacacgttt atagtgattg tatacggcaa cagctaacga
     7381 gcgttttgcg cgatcttgtc caatcacgta gttattcaat acttcaagaa tttctagtgg
     7441 tttagggact tcagtgaatt cgcgtacagc ttcttcataa aattcttcat caatgatttc
     7501 tttacatagg tcgatacatt cattacagat gtagacccct ggaccagcta cgatcttttt
     7561 cacttcttct tgggttttcc cgcaaaaaga acagcgtacg gtctcattgc tacttggatt
     7621 gtcatacatg gtcttcaccc cttaacttgc aaaaagtatg caagaaacta tcaaagactt
     7681 tacagtcttt tactatcata acatagttta gtaaaaagaa aaagtgttta acaaaggatc
     7741 aactgaccta tacctttgca ttttttactc ttaacaaaaa ataaggaact gtgacaaaat
     7801 cgtgtcacag tcccttattt cgaataaaca attttctaga agtagcttct tcagaaatga
     7861 tttattactt gatttctatt ctttcgcttc tgtcgctgta cctgtgatca attcgattgc
     7921 ttttttcatt gtcacatcat gttccagcat atcttctgtc aacacgcgtt tgatttgttc
     7981 gattggcatg ttgtatgttt ctgataattc ttggatttct gcattgattt cttcttctgt
     8041 tgcttgaaga ttttcagcag ctgcaattgc ttcgatcaca agatttgttc ttgtgcgcat
     8101 ttctgcttca ccttcgaatt gtttatgcaa gtcttcttct gtagaaccag ttaattgata
     8161 gtacatttca ggagagatac cttgacgttg catgttgttc aagaattcgt ccattgaacg
     8221 atgtacttca tcatgaacca tcacgtgtgg caattcaacg atttctgcgt tttcaacagc
     8281 catacggatc gctgcttcat cttttgcatc gtccgctgct ttttcttttg tttctactaa
     8341 ttctttgcga tatttttctt tcaattcgtc taatgttgat acttcgtcat caacatcttt
     8401 tgcgaattcg tcatctaatt caggcacttc ttttgctttt acttcatgga ttgtcacttt
     8461 gaagactgct tcttttccag caagatcttc tgcttgataa tcttctggga aagttacatt
     8521 tacatctaga ctttcacctg atttatgacc aactaattga tcttcaaaac ctggaatgaa
     8581 tgagcctgaa cctaattcaa gtgagtaatt ttcgcctttt ccgccatcaa acgcttcgcc
     8641 atctacaaag ccttcgaagt cgattactac tgtatcgcca ttttcagctg cagcatcttc
     8701 tttgataact aattcagctt gtgcttcttg ttcacgtttg atacgtgcat ccacgtcagc
     8761 atctgttact tcacggtctt gtttttcaac aactagatct ttatattgtc ctaattttac
     8821 ttctggtttc actgttactt cagcagtgat tacccagtct tgaccttttt ccatgctttc
     8881 aacatcgatt tttggttgag aaacaggatc gatgccagct tctttgacag cagcttcata
     8941 agcttctggt aatacagcat tcaatgcatc ttcatataaa gcttcttcac cgtacatacg
     9001 gttgaatact tgacgagaaa ctttcccttt acggaatcca ggtacgttca agcttttttt
     9061 cactttatta aacgcagttg ttaatccttt ttggatttcg tcttgcgcaa tcgtaaattt
     9121 taaaacacca tcattcgtgc cttttttttc aaatgttgca gtcatttaat tccctccgag
     9181 tttagaaatt cattttatac atcaaaaacg tttcatgcat acctttaaat agtacactaa
     9241 ccctttcaaa ttgtaaacat attgaatgga tagaatcctt gtttttcata acatttttat
     9301 ctttttcact gataaaatct aatggaagaa gatcatttgc tgcaaaattt tttctctttt
     9361 ttttaaaaaa tcttgttttt catcttctgt accttcatac atcgtttttc ctgtacacgc
     9421 ctctacagtc agttgaaacc agcgcttcgg gtcttcgatg tatgtatcat agacaggata
     9481 aacaattgca gattgcaacg tgaattcttc ttttaacacg gaactaagca gcgcatcttc
     9541 attcccgtaa cgatctgaaa atacacataa ttgctggtaa cttgcctgct gctgcggctt
     9601 tggcagatct tttggtatga ctttgactaa cttttcttca atcgtcaaat agaaaacagg
     9661 atggcattcg ttcaattgcc taagtgtctc cagtaatttt gcccttgcta aaatatggac
     9721 ctctggcgat acaataagtt tactcgctgt ttggataaac tcatgataag gaagctgttc
     9781 gatctcatca atagacgcaa gctgacgtgc aggttccaac gaaggaagtt cctccgattt
     9841 attgtggagt gccttgatct tctgcctctc catttgtccg gataattctt ctgcaaattg
     9901 gattttttca atgacccgct gctcgaaagc ttcataaaaa tctgtacttg ctatcaattt
     9961 tctagcatat aaaaaatctt gtgtactgat taacaagtca aaataaaatt cagcaaactc
    10021 ctcattttga agatactgtt tttcatgcaa gagtgcttgc ttcaatgctt cttttttctc
    10081 gtccaactcg taaagacaaa aaacaagcag gctattagcc tcaaagcttt ctttcaactc
    10141 gtaagctcgt tgaaataatt cttttgcctg ctgatattgc tggtttgcta gtgcttgttg
    10201 tgccactcgc attaaattct catatttttc tggaaaatca atcggcttca cgcagtgtcc
    10261 tcctcttgct catattcagc tcatgttcaa tagtagcaaa acaaaaaaag catgacaatt
    10321 aaaaataact gaagcaccct ctaaaagcta gattttagat ctgactttta gaaggtgctt
    10381 tcaactgtta ctgcttttta ttgctcatca gctgttgact tcctggttga acgctttgat
    10441 cagattgatc gtaacaacac ttgtattagt gaaaaaatcg cccagatgtt gctttttctg
    10501 attaaagact gctggaagat accctaacat cagcaaagga aattttagaa tgaaccggca
    10561 agcaccttct ctaactaaaa cggttgacca gctaagttct tcttcatcaa agctgatgac
    10621 tcgaatacca aagatcattt tcccaatcgt ttggccatga ttgaatttcg tcaataaaat
    10681 aaaatacgct agataaataa gtaaggctgt gaatccgtag agactcagat aagaatctga
    10741 aaaattaagc caacctagat ttttggcaat accaagtgtt aaacgcgtaa tagctccgat
    10801 acacaaaaga tcgaccaaga aggcaaacat tcggataaaa aaacctgcat agaaatactt
    10861 aggaaaatca tttgcttttg gcggttcatt tcttgtgtcc gtatactttt tccatttacg
    10921 ttgtttcttt ttgatttctt cgggcgtcaa aggctctctt tcaaaagagc tcagtacctt
    10981 ttgggaaaag ttggagtcag gtcctacagc aggctgctgt tgcttatctt tttcttgttc
    11041 cttattttca tttgaaagct ctgacatgct tactcacctc cgtaataata cattgctttt
    11101 ggtgattccg ctgtccctag attctcaaga acggataaga tctgactagt ctcagaaggc
    11161 ttcaatccct ggaattctgc tagtttactt cctaaccatg tactagcaaa cccagatggc
    11221 gtggaagaat attctactag ttccgcatct tcaagctgtt gttcctttcg tatagctttt
    11281 aaagcatctt caggaaatcc caattcatcg actaaaccta cttcttttgc ttggacacca
    11341 tcataaatcc ttccatcagc aatttttttg acttcttctt cagatttatt ccgtccctcg
    11401 ctgacgattg ctacaaaacg actatatgcg ctgtcgatat atgcttgaag caccgcttct
    11461 tcttcttttg tctctggtcg cgttcctgaa cccatatctt tcaacgctcc gcttttaact
    11521 gttgtatctt ccacacccag tttttctaga agtcctgaat aattcaatcc tgacatgatc
    11581 acaccaattg agccggtcac tgtttcttct gttgcaaaga ttttatctgc ttgagcagaa
    11641 atatagtagc caccgctagc tgccatgttt ttcatgctga catacattgg gatatcatgt
    11701 tctttacgaa tcgtatccaa tttcttagcg atttccgcac tttcgtagac accgccacca
    11761 ggagaattta cttctaaaaa gatacctttg actgttggat cttcttcaat cgccttcagt
    11821 tgttccataa aatttttatg attgtaacct tcagaagcaa ataaacctga agaccctccc
    11881 gcagcaatcg ttccatctac tgataatttt acgatttttt gcgtactgtc tccctcttcc
    11941 aacacatttg gagctagttc ttcatcccca tataaccaac tgttcaatcc ctcaatttga
    12001 tcgttttcct gaggcttagt caaactagct gaaactaacg aaaccacaaa taatcctgca
    12061 gcaatcagaa ctgctgccca acgtctttta ttcattcttt ctcctttcta atacaagttt
    12121 tttatgacga tcacagtttc tgactgctca gaagtgtcga accgctctgc tttttcttcc
    12181 cgcgcatacc cggaaaacga ctcttttgtt aattcatctt ctaccgtaaa ctcacgagct
    12241 tgagcaactt ccaaggcatc aggtgcgatt tcttggatgc tatcccagcc agtatctaaa
    12301 aatattttcg tatcatctga tacaccagct gatgcttcga atttggacaa ttgttttttt
    12361 aacattccca gtgtcatgat ctcaattttt gaatccattt ttactcctcc tctatccgat
    12421 tactttctat tgtaccgaac tcctgaaaaa gatgatagat aaaaacccat tattttttga
    12481 cataaaaagg acatttgaca aagaatttga tatataccaa tttatttttt attctttttt
    12541 tgttgacaag aacattcgca aaaggttatg attttaaatg tttccagata aaaaacaaaa
    12601 aggaggatag ttataccttt taggatagcg ccaggtctgt gtaaacagat gacgaggaga
    12661 gggtttatcg aaagattcgg cggatggccc tagggactgc actctacaga aaatccacaa
    12721 aaaatgtctg caaagataaa acaaaaggat tttcctgcag ctggaagcat tcatacgaat
    12781 tcattataga aagtaggatg ttttttatgt gcggaattgt tggaatgatt ggattaaaaa
    12841 atgtaacacc aggattgatt gacggtctag aaaaattaga ataccgtggt tatgattcag
    12901 ctggtatctt tgtctcagat ggcacaactg attatctggt caaagcacaa ggcagaattc
    12961 aaaatttgaa aaacaaaata aatattgata ctacaggaaa tataggtatt ggtcatacac
    13021 gatgggcaac tcacgggcaa ccttctgaag aaaacgccca tccacatact tcccaaagtg
    13081 gacgcttcgt gctcgttcac aacggcgtaa tcgaaaactt tgaagaactt aaaattgctt
    13141 atttagcaaa tgaccacttt attggtgaga ccgatactga gattatcgct catctaattg
    13201 aaactttcgc gaaggatact acaacgcaag aggcgttttt aaaagctttg cgggtcatca
    13261 aaggttctta cgctttcgct ttgattgatc ggacagcacc tgatgttatt tacgtcgcta
    13321 aaaataaaag tccactatta atcggactcg gcgatggatt caatgtgatt gccagcgatg
    13381 caatggctat gcttgctcat acgaaggaat tcgttgagat tgaagatgaa gagatggtta
    13441 ccgtcacatc agaaaaagtt attattcaaa attttgcagg tgacatcgta gaacgttctt
    13501 cattcgaagc acaagtagat gcttcagata tcgagaaagg tacctatcct ttttatatgc
    13561 tgaaagaaat cgacgaacag cctattatca tgcgtcgtat cgctcaaaaa tacgtaacag
    13621 aagacaatcg tgtctctctt gatcaaaagc tggtcgatac attgtctgat agcgatcgaa
    13681 tctatatcgt tgcttgcgga actagttacc atgcggggtt agcaggtaaa cagactttgg
    13741 aaaaattgac acagattcct gttgaggttc atttagccag tgaatttggc tataacacac
    13801 ctcttctttc aaaaaaacca ttctttattt tcttgagtca aagtggcgaa acagcagaca
    13861 gccgccaagt gctggtaaaa atcaaccgtc tcggctaccc ttcacttacg attacaaatg
    13921 ttgctggttc tactctttcg cgggaagcat cctttacact gctattgcat gctggacccg
    13981 aaatcgcagt agcatcaacg aaagcttata ctgcacaaat agctgtacta actttattag
    14041 ccaaagctat cggtgataaa aaagaatttg aaacttctct tgtattcgat atcactcatg
    14101 aattgagttt agttgctaat gcgatggaat cggtcatcgc ccaaaaagat tatttagaag
    14161 agttggcaga agtatatctc agcgatacaa gaaatgcctt ttacattgga cgtggtgctg
    14221 actacaacgt ttctcttgaa gctgctttga aattgaaaga aatcagttat atccaggcag
    14281 aaggttttgc cgctggcgaa ttgaaacatg gaacgattgc tttgatcgaa gaaggaacac
    14341 cagtgatcgg aatcatcagt gaagaagtga ctggtgcgca tactcgagga aacctgaaag
    14401 aagtcgaaag ccgtggcgct aaaacactag ttattgtctc agagggatta gaaaaggaaa
    14461 gtgaccagct ggtgctacca actgtccacc cttatctaac tactctaacc acagtcgtac
    14521 cgactcaatt acttgcatat tacgcaacgc tattacgggg attcgacgtt gacaaaccac
    14581 gtaatttagc gaaatcagtg acagtagaat aataaaagaa caaggaccag tgtcagacat
    14641 ctgacactgg tccttgttct tttatttttt atgaaaatat ctcttaatcc agtccgattt
    14701 cttctttgac tactgccgcg attttatcga catagtaatt aactttctca tcagtaggcg
    14761 cttctgccat cactcgaagt aatggttctg taccggaagg acgaactagg attcttcctt
    14821 ctgatcccat ttcagcttct gcctcttcaa tcactttttt gattgccgga acatccatcg
    14881 caccgttttt atcacttacg cggatattca ctaatttttg cggatagatt gttacctctg
    14941 ctgcaagctc tgataatttc ttacctgtct gtttcatgat attcagtaac tgaattcctg
    15001 aaagcatccc atctccagtt gtgttaaaat ctaagaaaat catgtgccca gactgctcgc
    15061 cgccaaagtt ataatcgttt ttgcgcattt cttctacaac gtaacgatca ccaacttgtg
    15121 taacgacatc tttcaaaccg attccttcca ccgctttgtg gaatcctaag ttactcatga
    15181 cagtcgtaac gatcgtatct tttttcaatc gatttttttc tgccaagtat ttagcacaga
    15241 taaacatgat tttatcaccg tcgacaatgt ttccaagttc atccaccgca ataatacgat
    15301 cgccatcgcc atcgaaagct agtccagcat ctgctccttt ttcaacgacc atctcagcta
    15361 aacgttctgg atgggtagag cctacgccgt cattgatatt taacccgtct ggatttgtgc
    15421 ccattgtata aaaatctgtt tcaagatcgg caaacaaacg attaacactt gttgaagttg
    15481 ctccgtttgc tgcatcgaca caaatggtca aaccggaaag gtcaccgttg atcgtttgta
    15541 caaggaattg agaatatttc aataagcctt ctggaaattc ttctacagtt cccaatcctt
    15601 cagctgatgg acgaggcaat tcatccactt cagcatctaa taatgcttca atttctagct
    15661 cttggtcatc tactagttta aaaccatctg caccgaaaaa tttgattcca ttatcttgtg
    15721 ctggattatg agaagcagaa atcatgaccc ctgcgcttgc tttttgcaaa cgtgtcagat
    15781 aagcaacacc tggtgtagag atcacaccta gctggaacac ttcgataccc accgataaaa
    15841 gtcctgaaat cagcgcttct tctaacattt gacctgagat tcttgtatcc cgccctacta
    15901 acacgcgtgg gcgttttcct tcttcttcat gctggcttag gacataacct ccgcaccgtc
    15961 ccagcttaaa tgcaagttct ggcgtaagtt ccttgttggc ttcaccgcgt acgccgtctg
    16021 ttccaaaata tttacccata gttgtaaaat tactccttta acttaatttt ctgaggaatt
    16081 tgttctgctc atttgtgttg attcgcttgt ttctgatgtt tcttctgtac ttgtggtcga
    16141 gctgcttgtc ccagattccg aactggaaga aatggttgtt gtcgatggtt ccgttcctga
    16201 atcagcagat gaaatacttc tactcgtact tgtattttct tgtgtccgac tgctcgtcga
    16261 agcagagcta ctgcttgacg tttgcaacac gggtgtaatc tccacactaa ctgattcggg
    16321 cttgatactt aacccctctt ctactggtat ttcaatttta cgagttgttc gatgattgat
    16381 acctgagaca ttgatcggta cagcaatact gtcaccgatc gatgcaagca aatcgctaga
    16441 gccgcttact tctgcttcca gttttgaaaa actgaaatca tagctttcta ccccggcagc
    16501 tggtgttcct tgctgtatcc cataaagtcg taccgacttg cttggcttga tcgaatcagc
    16561 tctcactgtt acttgcactg gatcagagac gatacttaat acttcccctg ctgcattcag
    16621 cgcctgtatt gggacctcac tattaatccc atcatctgtg accatcgaag cgtccacatc
    16681 agctactact cgtttgattt ctgccaatgt tttgtcacct gtagtgatag agactttttt
    16741 aggactaacg gaagtatcat caagttcata tccagatggt gtgaacgttg aaggaatcaa
    16801 cgtttccaca tcgaaatctt ttattacctt tttctcaacc gttactgtaa tagtcgatgg
    16861 ttcgatcttt gctgtgacag cactgctcaa attttgaatt tttagcggaa cttcatgtgt
    16921 tccttcgccc agcttagtga tatctgctgt gacgcggaac atccgtgtat cttcgtttgc
    16981 ctctgcattc aactgaactc ggtttgcact ggaaagtttg acagtcactg cattttcata
    17041 tccatggata tagtagcgct ttgaatcata agaaatcttg atcggcaccc ccgtaactgt
    17101 ttgattatac gcttcatttc cagaaagcgt atttggaacg gactggccat ttgcattgaa
    17161 gtacagcgca atactgaaca gcaatgcaat aaaactgtaa agaatgcttg tccgtttctc
    17221 ttttgagatc atttgcgatc ccctccctta gtcataccgt ctaggaaaga ttgaatcacg
    17281 tttttcttgt tttttgtttt ctcttcagca attagttctc tacgcaagat tgccaaatat
    17341 tcttgctggg ataagccagc catcagttca ttatctaacg tgatgctgac gtccccggtt
    17401 tcttcagaga caacgatggt aatcgcgtca ctgacttcgc ttataccgac agctgcccgg
    17461 tgtcgagtcc cgaattcttt agggatcaac atactttctg atagaggaag ataggcgctt
    17521 gctactgcga tctttccttc ttttacaata actgcaccgt catgcagcgg tgtattagga
    17581 ataaagatat tgatcagcag ctccccagtg atatctgcat ctaaagcaat ccctgtctca
    17641 atatactcat ctaatccagt atgacgttcg atagtgatca acgcaccgat ttttcgcttg
    17701 gacatatatt ggatggcttt gtcaaaagac aagatcatct tctcatcttc ctgctgttcg
    17761 ctttttgatt gtttgaaaag cgaactgcgt ccaagatgtt ccagtcctct ccggatttcc
    17821 ggctgaaaaa tcacgatagc agctatcacc ccgtacgtaa tgacttggtt catcagccaa
    17881 gacaaggtgt gcagaccaat gatttccgct acgattcgga taacaataaa aatagctaca
    17941 cctttcagaa gctgaatcgc ttttgtgcct cgcagcagtt ggatcagttt gtatacaaga
    18001 taccagacaa ccagaatatc aagtatgttc accaaaaaat tcagagagaa caagtcaccg
    18061 gaaaacattt gctgccaata gtccaaatta aaaagttccc cgatttgaaa tgacataaaa
    18121 agcctctctt ctcttttgag atttcctctc tagtatatca tatgttttaa ttttagaggc
    18181 tgatatgctc gtatttttct tgagaaaaac gcataatttt caagaaaatt gcaagtatgc
    18241 gttttatttt tctctgcaat aaatattttt aaacttcaga gaattattca ttatattttt
    18301 tctgttattt ttcctttttt tcttttgtag cttgttccat ttttttacgt cgttctgctc
    18361 tggcagctct tctagcagct cttctttctt ctgcttcaag gtccgtcgtt ttttcttttc
    18421 tagtcttaac gggtacatcg atagattcct ctggttcaag tcgtttcttg attttttcta
    18481 attctcccgt cagtgcagca tagttgtaaa aacgtgtttt agcgtcgtgg acagtctttt
    18541 caaataaagc ttttgcaaga tttggatttg cgttatctag cgaggaaaag cgaacttgtt
    18601 tcctcatgaa atcaggcata gcagagaaat caggtttttt gtagtccaaa gtcattgggt
    18661 tcttgttttt ttcgaccatt gtagggttat atcgatataa tgaccaataa ccagaagaaa
    18721 cagcttcttt tgcttcttta agcgattctt tcattccgcc aagcaagcca tgtgtgatac
    18781 aaggcgtata ggcaataatc agagaaggac caggatactt ttctgcttct tcaaatgcct
    18841 tgatcgtttg catttgattg gcacctgaag caatttgcgc cacataaaca tttccatatg
    18901 tcatcgccat cattcctaga tctttctttg aagcatactt tccactagcc gaaaatttag
    18961 cgattgccga agctggtgtt gcttttgagg tttgaccgcc agtattggaa tagacttcgt
    19021 tatccaaaac aaggatattc acgtctgctc cgctggcaag tacatgatcg atcccgccaa
    19081 aaccaatgtc gtaagcccat ccgtctccac caatcatcca ttggctgttt tttacgaata
    19141 gatcctttct cttgtatata tcctccagtt cagggaaaat tgatcgttcg ctttcgatcg
    19201 cagcttgcag ttttgctgct ctttgctgcg ttccttcact ctcaaacatg tgtactaacc
    19261 agtcttccat caattctcgt agttcttctg atacttttgg caatacttct ttgattgaac
    19321 ttgccaaagc ctcgcgacga gtctgtgccg ctagaagcat accataacca aattcagcat
    19381 tatcttccaa taaagaattt gaccatgcag gcccttgacc acattcattg gtcgtataag
    19441 gagaagcagg agaagcaccg ccccaaatag aagaacagcc tgtcgcattc gcgatcatca
    19501 ttcgatcacc gaacatttgt gtcaataatt ttacataagg tgtttcgcca cagcctgagc
    19561 aagcgcccga gaattcaaga agcggttgat tgaattgtgt agacaagaca gtattctttc
    19621 ctttgactgg atttgctttt tgtcttaatg tcattgcaaa agcccaattc acagcttgtt
    19681 ctttctgttc ttcataaggc ttcatcacta aagctttttc ttttgcggga caagcctcta
    19741 cacacagacc acaacctgta cagtcttcca ctgaaacttg gatacggtat tttacgccgt
    19801 ctgcgcctcg catttctctc acgataaatc cttctggcgc ttcttccatt tcctcttcat
    19861 ctgctaaaaa tggacggatg gcagcatgag gacaaacaaa ggcacattca ttacacatcg
    19921 tacagcgatc actaatccac tcaggtactt ctaaagcgac gccccgcttt tccatagaag
    19981 ccgttcctaa aggcatttcg ccagttgtca ttccatttgc tacaagtgta ccaacagaga
    20041 gttgatttcc ttcctgtgca ttcactggtt caagtatttc ttgtatataa ccagtgttcc
    20101 ttttattgat tttttcaggc atctccaacg ttctccaatg gtctgggatc gcgacttgat
    20161 gaagcagttc ggtcgtccga tcgattgctt gtatgttttt ttctacgata gccattgatt
    20221 tatgtccata gcttttcagg gcttcttctt ttagcagcgg aagcacctca tcaaaaggaa
    20281 tgatgtcagc taatttaaaa aaagccgttt ccattgccgt attgatccgg cgtcccaaac
    20341 cgacttcttg ggccaatctc atggcattga tcgtatagaa tctaatgtta ttttcagcca
    20401 agtaacgttt taattttaag ggcagatgcg tttctaattg ttcgtcgctc caaagagtat
    20461 tcaataaaaa aatgccacct ggcttcaatc ctttgaccaa gtcatagcta tgcaggtaag
    20521 ctggtgtgtg acaggcaaca aggtccgcat gctcgacaag atacgctgaa cgtatcggcg
    20581 tatctccaaa acgaagatga gagacagtca gaccgccaga ttttttcgaa tcataataaa
    20641 aatagccttg cgcatattta tcggtgtgat ctccaataat cttgatagct gatttatttg
    20701 ctccaactgt tccgtcagat ccaaatcccc aaaacttggc ctggaatgtt tgcggttctg
    20761 tcaaatccag actttccttt ggttccaaag attgataagt cacatcatcc acgatcccta
    20821 tggtaaaccg ttttttgcgt atgcttgggt cttttttcaa ttcatcaaaa actgctgaga
    20881 tttggtcggg agtcacatct ttagacccca atccgtagcg accaccaata acagccgggc
    20941 gaagttcaga atcatataac gcactttgaa cgtctaataa gagaggttct ccacctgccc
    21001 ctggttcttt acttcgatca agaacagcaa ttgtttttac tgtatgaggc aacttttgca
    21061 cgaatgtttc cactggaaaa ggacgataaa gatggatatt caaaaaacct gttttccgtc
    21121 cgtttgcatt caagtaatca atcgtttgtt caatcgtctg tgcaactgat cccatagaaa
    21181 caatgacttc ttccgcatcg tctgctccgt aataagtcac caagtcataa gaagttcctc
    21241 gtaatcggtt gatctctttc atatattttt gaacgatttc aggtaattta tcataatagg
    21301 ggttgatcgt ttcccgttgt tgaaaatgga tgtctggatt ctggttcgta ccactaacag
    21361 tcggatgatt gggattcatc cctcgtttac gaaatgaagc taatttctcc tgattgatca
    21421 gaggagctaa ttcttcatat tccaaaactt cgattttttg aatctcgtga ctcgtacgga
    21481 atccatcaaa gaaattcaaa aaagggactt ctccttcaat agaagcaaga tgggcaacag
    21541 gtgctaaatc catcacttct tgtacactgc tttcagctaa catagcaaat cctgtttgtc
    21601 ttgcagccat cacgtctccg tgatctccga aaatattcaa cgcatttgtc gtcactgccc
    21661 gactagcaac gtggaaaaca cttggcagta gttccccagc aatcttgtac atattcggta
    21721 tcatcaaaag cagcccttgt gaagcggtat atgtagttgt cagtgcacca gttttcaatg
    21781 atccatggac cacaccagct gctcctgctt cggattgcat ttctactact tttactggtt
    21841 gaccgaatac gttttctttt cctgctgctg accattgatc tactaattca gccatggtcg
    21901 aactgggtgt tattggatat attgcagcaa tctcggtaaa tgcataagaa atatatgcgg
    21961 ctgccgtatt gccatccatt gttttcattt ttcgcatgat tcatcatcct tgttcatatt
    22021 ctctcttatt atctgttcca ttataacgta aaacatgcca tttttttctt ttatttataa
    22081 aaatatttta catgtatcta tttgaattgg tcatctaatt tttagacaaa cagtctaaat
    22141 cgttgccttt ttttgtcaga catgtataaa ctataagcga aagaggtgtt ttaacatgga
    22201 tatatcagtg attgatgcaa cgaaaacaaa tacacaaaaa ggaatccttt atggttcatc
    22261 gaatgctcct aaaaaaatgg tcgaattcat caacttagct tgtccgtatt gccgacaatg
    22321 gtttgaagaa tcttatgagc tattagaaga agcagtccaa agcgggcaat tgcagcgagt
    22381 gatcaaattg ttcgataaag aaaaagaaag cttacagcga gggaacgtga tgcaccggta
    22441 tctcacaatc agcgatggcc aaaaagcgat caaagagatc aaacaaatat tcgatactca
    22501 agacgagtgg aaacatcttt ctctccaaga agtagcggat tttgcagtag ataaactaaa
    22561 gctgacagaa caaaaagacg aacagctgag ccaagctgtc atcaacgaag ctgagcaagc
    22621 acatattcga tttgttccaa ctgtcatctt gggtaaagaa atctttgatg aatctatttc
    22681 aatagaggaa ttaaaagaat tgatccaaac aaaataaaaa aataaggagc gtg
//
LOCUS       DAFLWC010000047        22731 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.048, whole genome shotgun sequence.
ACCESSION   DAFLWC010000047 DAFLWC010000000
VERSION     DAFLWC010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22731
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.048"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            112..3390
                     /locus_tag="L1V17_001656"
     CDS             112..3390
                     /locus_tag="L1V17_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HBN1236426.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(3931..5838)
                     /locus_tag="L1V17_001657"
     CDS             complement(3931..5838)
                     /locus_tag="L1V17_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HBN1236427.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            5968..6843
                     /locus_tag="L1V17_001658"
     CDS             5968..6843
                     /locus_tag="L1V17_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HBN1236428.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            6923..7897
                     /locus_tag="L1V17_001659"
     CDS             6923..7897
                     /locus_tag="L1V17_001659"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBN1236429.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            8077..9222
                     /locus_tag="L1V17_001660"
     CDS             8077..9222
                     /locus_tag="L1V17_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBN1236430.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            9359..9703
                     /locus_tag="L1V17_001661"
     CDS             9359..9703
                     /locus_tag="L1V17_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HBN1236431.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            9974..11260
                     /gene="efmA"
                     /locus_tag="L1V17_001662"
     CDS             9974..11260
                     /gene="efmA"
                     /locus_tag="L1V17_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HBN1236432.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(11398..11997)
                     /locus_tag="L1V17_001663"
     CDS             complement(11398..11997)
                     /locus_tag="L1V17_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HBN1236433.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            12401..13522
                     /gene="mnmA"
                     /locus_tag="L1V17_001664"
     CDS             12401..13522
                     /gene="mnmA"
                     /locus_tag="L1V17_001664"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBN1236434.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            13768..15189
                     /gene="arcD"
                     /locus_tag="L1V17_001665"
     CDS             13768..15189
                     /gene="arcD"
                     /locus_tag="L1V17_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HBN1236435.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            15203..16321
                     /locus_tag="L1V17_001666"
     CDS             15203..16321
                     /locus_tag="L1V17_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HBN1236436.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(16381..17673)
                     /locus_tag="L1V17_001667"
     CDS             complement(16381..17673)
                     /locus_tag="L1V17_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBN1236437.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            17805..18383
                     /locus_tag="L1V17_001668"
     CDS             17805..18383
                     /locus_tag="L1V17_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1236438.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            18512..18889
                     /locus_tag="L1V17_001669"
     CDS             18512..18889
                     /locus_tag="L1V17_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HBN1236439.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            18822..20894
                     /locus_tag="L1V17_001670"
     CDS             18822..20894
                     /locus_tag="L1V17_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBN1236440.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(21105..22052)
                     /locus_tag="L1V17_001671"
     CDS             complement(21105..22052)
                     /locus_tag="L1V17_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBN1236441.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            22298..>22731
                     /locus_tag="L1V17_001672"
     CDS             22298..>22731
                     /locus_tag="L1V17_001672"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBN1236442.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQ"
BASE COUNT         7360 a         4146 c         4815 g         6410 t
ORIGIN      
        1 ttttcttttt ataaaataca cttattataa ttttgttttt tattgacagt aaaaataaat
       61 taggtaatac tttaagtaaa cgctttctaa tttgttacgg gaggaataca cttgttaaaa
      121 aaacgtataa aatacagtgc gctaatgatg aatctcctta tgctcagtac cccggtttta
      181 atttctgtcg ttgaagttgc tgctaacgaa caacagtctg tgaacgaaga aaatgcacac
      241 gtgaacattg aagggatgtc aacaatggag gaaataccaa gaactagtga agatatggat
      301 acggaagaag gaaatgatcc tatgatgaaa gaatcagaaa atgaaaagac aaaaaagcaa
      361 tctgaagaag caaatgaaga gtggaaaggg gttgttttcg gagaaagcac aagtgctagt
      421 aggtatgcca ttgaaccatt agaagacggc gtgcggctct cttccacgaa taacggcgga
      481 aaattccagt caagcggatc agatggaatg acctattatt atcaagcaat ccccaaagac
      541 atcaacttta ggatgcgggc gacgatcgaa atagaatctt ggacctatac gaatgcccaa
      601 gaaggatttg ctttaatggt aagagacgca gtaccaaaaa atcatttgtt tgggcaggca
      661 ttttattcaa attcatttgc catactaggc agtcggatcg aatatgtctg ggactcggat
      721 agacaagaag tggtcaacac gagcggcagc aaatatacga tgcgacttgg attggggaca
      781 cgggcaatca caggaatatc atctgaagat ccgcaagctg cgccagctcc tgggagtgtc
      841 tcagtggaaa caacaccttt agagacttca gcagggttct tggaaaaaga aacaggttct
      901 tataatatat tcggaaacgg tcatgggaat ctgtttccgg ccacgaactc gattactaaa
      961 ctggacgtag agatgaaaaa aacgaatact ggtttagagg catattatta cgatcctgaa
     1021 acaggagaag aaatggcttc tgacatcatg tatgactggg aaaaattata cgcttcagat
     1081 gaatcggtta tttatgcagg atttgctgca gcaaggaata tgacgatcaa ggtagaagga
     1141 atcgaagttg cttactcaga tcctgcgaca gatcctcctg ggcaagaaag acctactcgc
     1201 ttgattgatc cgatttacac tgtgacctct agtaatcatt caggaaacca agatcatact
     1261 atgtccttta gagcaaatgc tgacggatta ttgacaatta aaaataaagc aacaggagag
     1321 gtgcttaaga acgcaaaaaa cttggctatc actgcgaatc gggaatttga ttatcagaca
     1381 aaactgatgg aaggaacgaa cgaatttact ttcagtttta cgccagataa aaactatccg
     1441 ccagaagaat acgtagagat gactagttat gaaacaaaag agattcttca tacagtggac
     1501 taccgtaaac ctaaatattc gacagtttat gtaacaccag aagggtcaga tgcaggaaac
     1561 ggaagcagac aaaatccatt atctctgaca caagcattga gatacgcata tgctgggcag
     1621 acaatcgtca tggcgcctgg aacttattcc ttcgaaagag gattgacgat tccaaaaggc
     1681 gttaacggga caagagaaaa cccgattcag ttgattgcag agaaaaatcc agaaaacaag
     1741 cgtcctgtac ttgattttaa aggaactgga aatgggatga cactgttcag tcactactgg
     1801 ggtttacgag ggtttgacat tacaaatagt gcagctatgc aaaaaggatt acagatttct
     1861 ggaaatcata atttgatcga agagattcat gcttatcgga atggaaatac aggaatccaa
     1921 atcagcggta gctcaaatga tcctttcgaa gcatggcccg cgcataactt agtcaagaac
     1981 tgtacatctt ttgaaaatgc cgatccagga tttgaagatg ccgatggatt tgcggccaaa
     2041 ctgacaatag gagaaggaaa tgtatttgac ggttgtatcg cgtatcataa tgcagatgac
     2101 ggttgggacc tttttgctaa aaatgaaaca ggttcgatcg gaaaagtaat catcaaaaac
     2161 tcagttgctt atcgaaacgg ctgggtacca ggaattgagg gagaaggtaa cggtaatgga
     2221 ttcaaaatgg gcggttcttc tttaacgggc cctcatgaat tgatcaatag tttgtctttc
     2281 gaaaatcttg cgaaaggaat cgattccaat agcggaacag atattatcgt caatagcagt
     2341 acaagtttta ataacggttc atataatgtg gctctttata cctcttcagc aggaaacaca
     2401 gactaccatg cttctggtat cttatctttc cgaacagaga atcttgagat gagagagcag
     2461 atccgcccat tgaatcaaaa cgaagatcaa atctaccact cgttgaacta ctattggaat
     2521 gaacgagaga aacaatcaga aaatactctt ggacatacca tatcaaaaga ttggatcgag
     2581 tctctaaata catgttcgaa agaaggtcag cagcctgtta cgcgctatga aaatggaagt
     2641 atccatgttc atggactgat gcagattaaa ccggggaatc gtcaaacaga aaaggaaaga
     2701 gtggatggtc ttccattatc tgtaggtgct atttttgacg gagaaacctc accgtcttcg
     2761 gaatatccag agtatgcaat cgtacaagaa ccaaatcaga caaaaccaaa tgaacaaaat
     2821 aatccgatta ttatacaaga agcaaatggt gtggcggaga atgcagaagg aaatatcatt
     2881 gaactgaagc cttttacagt ttttgtgtca actttcacac caaatcaagg aacgcctgtc
     2941 tttgaagata tgcgttattt cccagaaaag atccaaatcg ttgaaacaca gtcaagtgct
     3001 caattttcta atcataccgc tattttttca gcaccttcaa aaggagaata tacgctagaa
     3061 gtcacttatc gttcggaaat atttgatggg gaaaaatggt ctgctcatac agaatctgtt
     3121 acccagcaaa aagcgatcac tgtgcgagaa actgccgatg tgcccccggg aaatgacaaa
     3181 ccagaaagag aaaatccagg aaatgaatca ccaaatggaa aaccaaatgg aaaaccttct
     3241 catccggata ggacagcaaa agaaagtgaa aaaaatggca ctcaaggact cccaaaaacg
     3301 ggagaattta ataacccgtt gctagcatta gctggaggaa ttttgttaat cggtgtagtt
     3361 gtttatgtca tgaaacagcg aaaaaaataa gtggaatttc tccttttatg atgtaaaaca
     3421 attgactgag gaaagtaaaa atagaaggaa atgagaccaa tagatgtctc acttccttct
     3481 atctttttat agatgaggtt ctccttgctg cttttgattg gctgttctta ttacttgatg
     3541 caggacagct ttttcacaat ctctccacta aacggtgttc aatcagctga ccctcggtat
     3601 tagctcaaca aacggcaaaa tatgaggaac tatttttccg tttttttctc taatactcag
     3661 gtcaggacgc tgatttcaca acctctcgat aaacggtgtt caaaagccag tttctcggta
     3721 gtaagtcaaa tttatgcaaa aatgtggaaa gccattttca caaaattttt cttactactt
     3781 gaaactaagc agctttttca caacctctaa tacatggtat tccagaagta acttcttcga
     3841 aaaataagcc gaaatgtcac aaaaatttga gaagcgattt tcccaaattc cttcttattt
     3901 cttgaagctg accacttctg gcacaacctc ttaccagatt cgcactcttt tttctggcgc
     3961 tagatacata gcgtcttgtt ccgtgatacc aaatgtttca tagaattcgt caaggttttt
     4021 tggttgcacg tttgctcgga gtttagcagg ggcatggaca tcgatttgca gtaaaagttg
     4081 ttggtattct ttttttgctt ttgtacgcca aatcgttgcc caattgacaa agaattcctc
     4141 gatagaaaga tctgattccg tttttgctgc ttccaatgca cagcttagac cgcctgcatc
     4201 agcaatattt tccgaaacgg ttaattttcc gtttactttt ccgtcagcaa aaggcagacc
     4261 atcgaattct tcgatcattg cttgtgcttt gttttgaaat tgtgtaagat cttcttctgt
     4321 ccaccagttg ttcaagttgc catattcgtc aaataaagcg ccgttattat caaatgcatg
     4381 ggaaatctca tgagcgataa cagctccgat tccaccataa ttagcagagc ttgattgttc
     4441 tagactgtaa aatggtgctt gaaggatcgc tgccggaaag acgatcacat tccgaaatgg
     4501 atgataataa gcattgaccg tgtcagcact catttcccat tctgaacgat ccactggttt
     4561 gttccatttg ctgaaacgat cttttaatgt gagtttgctg aaaacaagag tatttgaaag
     4621 caaagtacca ccctgatctg caggtactgt tttgaactgg tcgaataatg ctgggatctt
     4681 atcggggtag cctacttgga tacctaagtt atttaatttt atgacggctt tttcttttgt
     4741 tgcatcccca agccagtcat tttcttctag acgtttttta taaacggcga tcattttttt
     4801 caccatttgt tctacgtctt ttttagcagc ttcgccaaaa tatttttttc cgtagtaatc
     4861 gccaactact tgatcgaatt gtccagaggc aaggtaatac gctgcttttt tctgaggcat
     4921 tgcttcgtct gttccagaca atacgcgaga atagattccg ctgacttggc ggaattcttc
     4981 tgatagataa ccactaagag aacgtactgt tttaatgatc atccagcttt tgaataacgg
     5041 aaaatgagct tctgtcagga tgtcattcaa atgatcgaag tacactggat cagttacgat
     5101 cactttatct ggagttgtcc caatcaaacc cgtgacaagt tttttcaagt ccagtttatc
     5161 tgtgtattta ataaatgtat caaaagattg cggattatac attttgctgt aatctgcgtt
     5221 ttcttctgca ctttttacat gaggagcaat caatttatca aattgcactg cttgttccgt
     5281 gattgcttct gcctgacttt tttctttgcc ggcaagctct aataactgaa cagccatatc
     5341 aaagaaaacg cctattagtt gtgcaccgtt gggatggtct gatgcataat acgtcttatc
     5401 tggaaggaat aaagaaggcg gataagcaaa gaaggcgttc gtttgcgcat tcttcatatc
     5461 tgcatctaca tccagattaa atggcaatgg taatgtatcc aacagccatt ctggaaattg
     5521 cttattcaat tcgtcgaaag actgcaatga ttcaactttt tcgattatag gttgaagcgg
     5581 ttgagcatgc aactcatttc ttcggtcata atcgtttgcc agttgataat atgcaaggaa
     5641 atgtttcatt ttttctgaag acactttttc tggatgggca agcagatcgt ctgtttctcc
     5701 catcaaaagt tggtcgatcc cgtcaactaa atcttggaaa ccgcctgtag ctggtttatc
     5761 tgcagggatt tttgctgttt tttgccattc ttcattgact gcttcataga aatcttgttt
     5821 caatcgttct ttgttcattc atcgatcgct ccttttttgt ttcgtgtgcc cattatctta
     5881 caaaatgaag gaattaacaa atagaacata aaaaattgaa aattcgaaca atcaaactga
     5941 tttgtttttt tcaatccttc acttataatg aaaaaaagga ggcgatccca actgaatcaa
     6001 gtagtggata aacctttata tttcaaagta gataaaaaaa ttaaaaaatt agccagcact
     6061 cagcagctgc agtcaagaaa aagtaaattg ctttttttag ctctggtttt tgaagatcaa
     6121 agttatgtga ttatcgatca atcaggacat ccggtagaat attctccagc aaaatatact
     6181 tatcaagagg gtctttcttg taaaaaatgg aagctgatca atgaagagcc aatcgagtta
     6241 tctagatgga tcaacagaaa agaagatatt cccgttttga tcgaagaaaa aaggtcagga
     6301 aaggaactcg caaattgctg ggtgggattg ccagaagaac gttttttgag gtataagaaa
     6361 tgggctaccc cctcaggcta tctttgtggt acttacgcgg cagcagttct ccttgcctat
     6421 tatcaagact atcgtaaggg gtggatgctt ccaaatgaga ttcgcaagaa aaatacggct
     6481 gattcgttgg ttttgacgaa ggcattgcgt agccagatcc aaccactagg acttcctacg
     6541 attccttttc aggttagtac agggatttct agttttttaa agaagaatgg caatcatgag
     6601 cgtgcacgag caactcttct aggttcatgg cagcgagcta caaaacgtat acgtgaaggc
     6661 aaacctgtga tgattggtat tttgaaagta cttggcagta catatggcaa tcattgggtg
     6721 acagcgtacg cttattttga aactgaaaca ggagaacgtt attacaaagt acacgacaac
     6781 tggggcgatt atcataaagt cattcctgcc agttggagta acggaacagt ttcacttcct
     6841 taagaatttg ctgaaattaa cagaaaatct tggaaaaata tgttaaacta tcgaagaata
     6901 gagaagtttt ggggaggact acatgagtaa taagtatcag gatgacacgt tgaagatttt
     6961 tagtttgaat ggcaaccgtc cattagctga aaaaatcgcg aaagtgttcg gaacagaatt
     7021 aggtaaaagc gtcgtgaagc aatttagtga tggcgagatt tccatcaata tcgaagaaag
     7081 tattcgaggg gatcatgtgt atatcgttca atcaacgaat gcacctgtca atgattacta
     7141 tatggaacta ctgatcatga tcgatgcaat gaagcgagca agtgcgaaaa cgatcaatgt
     7201 cgtattgcct tactatgggt atgctaggca agaccgcacg gcgaaacctc atgaaccgat
     7261 cactgcgaaa ttgatcgcta acttgatcga agaagcaggg gcaactcgag tactgacttt
     7321 agatctgcac acggttcaag tacaaggatt ctttgatatt cctgtagata atttatttac
     7381 gatgccgttg tttgctcatt attaccgtca attaggtctg acgggagatg acatcgtagt
     7441 tgtttcgcca aaaaacagcg gtgttcagcg tgcacgtagt ctttcagaat atttgaacag
     7501 cacattagcc atcgtagatc atgcagatga tgcttcaact gagggtggtt atgtgatcgg
     7561 tgatgttcaa ggaaagacat gtatcatggt agatgatatc ttgaacacag gagcaacgct
     7621 tgcacgagca gcaaatgtat taaaagaaaa cggcgcaaaa gaagtatatg cctgtgcgtc
     7681 acatggatta ttgtccgatc atgcgaaaag tattttagac aatgcaccaa tcaaagatat
     7741 ttgtatcact gattctgttt tcacagaaga aaatcgtcat ccagaaaact taacaatcgt
     7801 tacatgttca gaattaatgg gtgaagcggt caaacgcatc catgaaaata caccgatgag
     7861 tccgttattc cgtctggaag aaaaagaatt cgaataaaca aaaaaaagag ggaaagaagt
     7921 tgtgacagaa gtgagcagct tcaaggagct gcgacaagac ttttgtcaca gctccttttt
     7981 tctatgccca tgaaacgtcc tctagacaaa aatgagctct tctttggttt gttcgctatt
     8041 ttatgctaga atgtgcctag caataatttg gaagggatga atgaagtgaa aactatttat
     8101 ctggatcatg cggcaactac ccccatgcat ccacaagtaa ttgaagcgat gacggcaatc
     8161 atgcaagaca cgtttggaaa tccttcaagc atacatggat ttggtcgcca cgcgcatgaa
     8221 aaattggaaa cagcaagaca aatcattgca gacagtctgc aagcaaaacc tcacgagatc
     8281 atctttaaca gtgggggaac agaaggggat aatacagcta tcttagaaac agcgttctcg
     8341 cgtcaaaaag aaggcagaca tctaatcact acagctatcg aacatcctgc tgttcttaat
     8401 accatgaaat atttagagac aaaggggttt gacgttacat atctgcctgt agatgaaaaa
     8461 gggaatctgt cgatcgaaga ggtcaaaaaa gcgttacgag aagatacgat cttggtctct
     8521 gtgatgtacg ggaacaatga aatcggaaat ttgatgccaa tcaaagaaat cggtgaactt
     8581 ttagcggatc atccagctta tttccataca gatgcggtac aagcgtacgg aaaccaaacg
     8641 atccatccag aagaattagg aatcgattta ttaagtatct ctgctcataa aatcaatggg
     8701 ccaaaaggcg tcggtttctt atataaacga gacggagtaa atatccctgc attgctttta
     8761 ggcggggagc aggaagaaaa gcggcgtgca ggtacagaaa atttagcagg gatctggggt
     8821 atggcaaaag cagttgaact gctgtcacct gaagaacgtg aagcacgtaa caacaaatat
     8881 aaaggattcc agcaattgat tcttgataca ttagaagcaa acgaaatccc ttatcaagta
     8941 aatggtgatt taacgaataa actccctcat gtgttgaatc ttcgcttaat tggcgaagca
     9001 aatgatttgc tactgatgaa gcttgatctt aatggggtcg ctatttctac tggttcagct
     9061 tgtacagcag gaaatatcga gccttcacac gtattagaag caatgtatgg agaagataca
     9121 ccgatactaa aagaatccat ccgtatcagc tttggtttgg gaaataccga agacgacatc
     9181 cagtatttcc ttgatcaatt agttcgtgct gtcaaaaaat aactagtgaa gtcattctta
     9241 tatgaacaga tgtctgagag aacgccttca ttttttaggg aacttaactg aaaaacctag
     9301 taaaaatcag gataaacttt tataataaag agaaactaat tttatcgagg tgaaaatcat
     9361 ggcatttgaa acaacagcaa cggtactggg cgcaccaatt agctatcgtt tgcatcctga
     9421 tgcaaaaaga tatacattgc gcgataatgg atttacagaa acaaacggag gcaattatca
     9481 attgatccga ccattagatg ccacgccgca aagcaaagaa ggattcaaat taaaaatcac
     9541 tgtatcaaaa gatattcaaa cattgaaaat gtcgatcact acagcaaatg gattgaaagc
     9601 agtcaatatt ttcaaagatc caaaacagaa aatgagccaa gataaatttt attttctgat
     9661 ggatgggatg attagccgtg ggttattcga aaaagtcgaa tgatctgtgg atataaaaag
     9721 acaactagtt ttgaaacggc ctattgttag atgactaact ttgtaaggac gacgcaaatt
     9781 agttgtcttt tttattttta aatttaacac atgttgttat ttttaatatt ttgctgattt
     9841 attgtttcta agtaaagaaa tttaaattga aacgattgtt atttagggaa aaaggtattt
     9901 tttgaaaaaa gaatcccgta taatgattgt tgtgcaaacg ctatacaaaa tgaaaaagaa
     9961 aagagggatg tttatggaaa atgaacagtc ggtcgtttta acgaattgga agagaaatta
    10021 tttgttcttt ttatcgggac agtttttgtc aggaatcact agtatggtcg tccaatatgc
    10081 gatcatctgg tatttgacaa gagaaaccgg ttcggcgaca attttgagtt ttgctacttt
    10141 actaggaatg attcccatgg ttttactaag cccatttgta ggaccgctag tggatcgctg
    10201 ggataaaaaa gctcttttga ttgtcacgga tattattgta gcgattttcg cgcttatttt
    10261 agcagtagtc ggaacgattt cagaatcctt cccgatttgg ctagtttttg tgtctttgtt
    10321 tatgcgttcg gtcgcacaaa cattccaaat gccaacgatc cagtcgatta tgccgacaat
    10381 cgttccatct tctcacataa caaggacgaa tggacagtta ggaatggtcc aatcagcgaa
    10441 tttcatcatt gcgccagctc taggtgcggc tttgttttca gtcgttcctg tcaattacct
    10501 tattttatta gatgtattgg gggcagtttt tggtgtcggc ttattgattt ttgtgaagat
    10561 cccaaaagtt tctcctgaaa tattggaagt tccgcttact atttttaaag atgcaaaatt
    10621 tgggctgcag caattgatgg ataataaagg gttatggtac ataacgatca atggtgcatt
    10681 tgtgatgctg ttgttcatgc cagcaatcag tctgtatcca ttgatgacgc tagattactt
    10741 tggtggttcc gttggacagg cgggagcagt ggaagtagtc tacgcagtcg gaatgctctt
    10801 aggcggtgca ctgatcagtt ttataggaac atggaaagac cgaatgaaac ctattattat
    10861 agcctacatc attatgggcc tgacgatcgg tgcaagcgga ttggttccaa acgatagtca
    10921 agggttcttg tactttctta tcttgaatgc aggagcaggt tgtgcaacgc catatttcaa
    10981 tacactgctg atggcaatga tccagcagag ttatgaatcg aatgttttag gtcgtgtctt
    11041 agggaacttc aactctttga tgaacctggc aggtccaatt ggattattat ttgcaggacc
    11101 attagctgat cgtttagggg tagaaaaaat gttcttgttt tccggaatcg ggattttatt
    11161 atgcggaatc gttttatttt taacgtcagc tgcccgaaat tatgataaag aattacagaa
    11221 aaaactggta aaagaacacc atgagcaaaa agacgaatag tatggaatgg agttgtgaca
    11281 gaagtcttgt tacaactcca tttctgatcc taatgttcct gtggcaataa gcctactcaa
    11341 atgaaaaata tgagtaatta tctttatttg tttaatactt gatatagggc agttttttca
    11401 cgacctatcg tacttcctct ttgcttcata gatttctttg atttgttgct cagataacgg
    11461 agtgccaaat ggtagttttt cctttaagag ttctctttcc ggtgcgtcta cgcctacatt
    11521 gacatcgttc tcgataggta cgctgtaatg atggatatgt ccatgaagat tgcggatagt
    11581 gtcgttaggc ccgagcaaca tcggataatg agtcaagtaa tattgttgat ggtcgaattt
    11641 aacgatggca cctacatcat aaaaataaaa tttgggactt ccgtcagtaa gcctaggatc
    11701 atttttttct aaataacgga aaaaagcgcg actgtcatgg ttccctttga tcaagtggat
    11761 tgttccttgc agttgagtga ccagttccaa aatttctgca tttgcttttt catattgcgg
    11821 atgcatagca aggtcgccta gatgataaac atggtcggtt tcttttatta ctgcattcca
    11881 gctagtgatc aactgttggt tcatttcatc cacatttgca aagagccgcg gagcaaagtc
    11941 gttttttcct aataagcgtt catggaaaaa gtgcatatca ctgataaagt aattcatgta
    12001 tcttttgcct cccttttttc ttagagtaaa caaaatcact tatctgagca actcataaca
    12061 tctaaaaaga aaaggttgta aatgagacgt gcagctttaa gcgataagaa gcaattttga
    12121 aaaatagttt ttcacaattt ataaaattat tccttattgc cgaaaggctg gcccttttta
    12181 tgagtatgcc aattttttat atcgaatgct caaaagatga gtgatttttt ggttgactat
    12241 catgtttgtg tactgaatag gtccagtaga acagtatttt tacgacttga taattaaggg
    12301 atgaaatttt cagaaatatg acgtataatg taaaatactg aaaagttgcg accttcaact
    12361 cgtagatgtt tcagaatcta attgaaatga tggtgatatc atgacagaca acagcaaaac
    12421 acgcgttgtc gtagggatga gcggcggtgt cgactcatct gtaacagcac ttttgttaaa
    12481 ggaacaagga tacgacgtga tcggaatatt catgaaaaat tgggatgaca cggacgaaaa
    12541 cggtgtatgc acggccacgg aagattataa ggatgtagcg aaagtagctg ctcaaatcgg
    12601 gattccttat tactctgtga attttgaaaa agaatattgg gatcgtgtat ttgaatattt
    12661 cctagccgaa taccgcgcag gacgtacacc taacccagac gtgatgtgca acaaagaaat
    12721 caaattcaaa gcattcttgg attatgcaat ggatcttggc gccgattatg tagctactgg
    12781 acattatgcg caagtcactc gcgatgaaaa cggcgtggtc cacatgcttc gtggagtaga
    12841 caataataaa gatcaaactt acttccttag ccaattatca caagaacagc tttcaaaaac
    12901 gatgttccct ctaggcggca tggaaaaatc agaagtacgg gcaattgctg aacgcgcagg
    12961 ccttgcgact gctaagaaaa aagattcaac gggaatctgc tttattggtg aaaagaactt
    13021 caaacaattt ttgagcaact atctgccagc aaaaaaagga aatatggtca ctcttgatgg
    13081 tgaagtcaaa ggacaacatg ctggcttgat gtattatacg attggtcaac gtcaaggact
    13141 agggatcggt ggcggaggag attcgcaaga accctggttt gttgtaggaa aagatctagc
    13201 gacaaacaca ttatatgtgg ggcaagggtt ccatcatcct gcattgtatg ccacaagctt
    13261 ggatgcaagt gaaatccact ttacgacgaa tgaaccaatg ccaaaagaat tcaagtgtac
    13321 agcgaaattc cgttatcgtc agcaagacgt tcctgtgaca gttcgcttat tggatgataa
    13381 tcgtgcagaa gtcgtattcg acgaacctgt acgtgcaatc actcctggac aagcagttgt
    13441 attttatgat ggaatggaat gtctgggtgg tggtttgatc gaccacgcat atcaagaaac
    13501 aaaagtttta caatacgttt aagcgatatt aaatgaatca aaacagctat ggctaacaaa
    13561 agaaacacct tttcttttgg atagcatagc tgtttttttg caataaaatt aatttttatt
    13621 cattttatac ttgaaatact tgtgtaaaaa gttcataata tccaataata tgaataaagt
    13681 tgctttttgt taagcaagag cagttgcaaa atagaaggga atcttttgca agtgatttgt
    13741 tcaattttat aagtgagggt gatggaaatg gaaaagaaat cgacgggtat tagcaaatgg
    13801 ggactggttg ctctggttgt cagttcgtca atcggaagcg gtgtgtttgg gatcacaagt
    13861 gatctggcta gttctgcagc tccagggcca gcgatccttt catggataat cgttgggatt
    13921 ggtattttag ctttggtatt atcgctgaat catttaggag aaaagcgtcc agatctagat
    13981 ggtggtattt tcggttacgc ggaagcttca tttggtaaat taggtggctt catcagtggt
    14041 tggggttact ggttgtctgc gtggctggga aatgttgctt ttgcaacgat gctgatgagc
    14101 gccatgggag aatttttccc gatattcaaa ggtggacaaa atgttccttc tattttattt
    14161 gcaagtattt ttatttgggg tctgacttta ttagtaaaca atggagttga aggagcgagc
    14221 gtcatcaata caatcgtgac gatctgtaaa ttagtgccat tattcctatt tttaatattt
    14281 gtatttatcg catttaaagt gaatatattc actgctgatt tttggggtaa cgtatctgat
    14341 aatctagtga atggaacagg gcagcaagga acgatctggt tgcagattaa aggttgtttg
    14401 atggttatga tgtgggtctt tgtagggatc gaaggcgcaa gtgttttagc caaccgcgcg
    14461 aagaaacgtt cagaagccca gcaagcatcg atcattggtc tgctttgttt attgtttatc
    14521 tatatccttg cttcgatctt gccatacggc gtcttatctc aagaagagtt agcaactatt
    14581 tcacaacctg ctatggcaaa tattttaaaa ggaatcgtgg gaaattgggg agcagcgctg
    14641 atcaatatcg gcttgattat ttcgatcatt ggttcttggt tgtcttggac gatgctccca
    14701 gcagaaacaa cgatgttgat ggctcgagac ggtctgttgc cgaaaggttg gggaaaaacg
    14761 aataaaaaaa atgccccaac ttattcgtta gttgttactg caatcttgac taatctattc
    14821 ttattgactt tcttagttac tgattatgcc tatcaatttg cctattcttt atgtacagcg
    14881 gcaattttga tttgttatct acttgtcggg atctatcaag tccagttttc tttaaaagaa
    14941 ggaatcaaaa aacaagtagt gatcggtggg attgctgtag tttttgaatt gatgggcatc
    15001 attttagcag gattttctta tgtcctttta tgtagtattg cctatcttcc tggtttttgc
    15061 ttctactgga tcgcttgtcg tgaaaccaaa catcaaatta cgggaaaaga aaaagtaatg
    15121 attgggctga tttgtgtggc cgcactgctt tcaatcgggt tgcttgctgt aggctggatc
    15181 aagatataag ggggaaagaa acatgaaaat cgcaaatttc ggtgtagaag aatggctaaa
    15241 taaatgggaa aagaaagcgg tatatgatat tgcacaaagc tcgatcgaag cattgacatt
    15301 agacgaactc gttggcttag atgggactag cgtaagtaaa tttttcgaaa aacgcaaaaa
    15361 cgaaccattg gactatggct ggatcgaagg atcagatgtt ttcaaacaag aagtcgcttc
    15421 tctttatcaa accgtcgatc cggaaaacat cttacaaacg aatggagcga ctggtgctaa
    15481 tcttttagct ctatacgcgt tagtggaagc aggagaccat gttgtttcga tgcttcctac
    15541 ttatcagcaa ttatatgaca tccccaaatc tttaggtgcc gctgttgact ttgttcattt
    15601 gaaggaagaa gaagattggc agtttgattt agaacagcta gaagccttag tcaaacctga
    15661 aacaaaaatc atctgtttga atagtgcaaa caatcctaca ggcacattgc tagatcggaa
    15721 aactttagaa aaaatcgcag aaattgctcg tacagtagat gcatatgtat tgatagatga
    15781 agtatatgcg cctttaacgg ataaaggtga attcttgtcg atcgtagatg tctatgaaaa
    15841 aggtatagca accaattccc tatccaaaac ctactccatt ccaggtattc gtattggctg
    15901 gacagctact ggacctgagt tggcagaagt ttttcgaaag tatcgagact acacgatgat
    15961 ttgcggcgga gtcctgtcag atgatcttgc tgtacatgca ttgaagaata aagaaaaaat
    16021 attggcgcga aacaaaaaga tcattacaga gaaccttgtg attttaaaac aatgggtagc
    16081 caatgaaccg aaagttgaac ttgtcgctcc caattacgtc tctacttctt tcattaaatt
    16141 agccatcgaa gaagatgacc agacattttg tatcaattta ttagaagaaa caggagtact
    16201 attagtacca ggaagtgcct ttgatttacc gaagcatgcc cgactaggtt actgttgtaa
    16261 aaaagaaacc ttggaaaagg gattattcct cttatctgag ttcttgaaaa aacaggccta
    16321 aacaaaaaca ctgcaaggac agtctgtgac aactgttcaa gcagtgtttt tcatttacgc
    16381 ttattgtcta tgagaaggag agtgccctga agctatggag actcctgaag ctttttcttc
    16441 tgcagtttct tgctgatgga tctcttgtgt attgtgtcgt acaagcaaga agttgaccaa
    16501 aacaagaaga gaagtcgaaa gaaagacgcc gcgataacca aatgcactgg aaacactgga
    16561 gccgatcata ggccctacta cgttaccagt tgcttggaaa gattggttat aactgaagat
    16621 ccgtccagca gcttgatgag gcgaatattt tgtgatcaat gcttggacag cagggagcag
    16681 acaagcatca gagataccaa tcaaaaaacg taaggcagct aattgccaaa cattcgtgac
    16741 gaatgccatt gggatataaa ccagaatcgc aaaacccaaa ccaatcgcaa gtattctttc
    16801 actcccaatc ttgtcaccta agcgaccaaa tcttggagcg gctatcaaag tggcaatccc
    16861 aggtatcgaa gcaatgattc cgctgatcaa cgtaacattc ccatgtccat gcagcaattg
    16921 gcgaatgtac agactgatga ttggactaat ggaattgttg gatgcttgga tgatcatcgt
    16981 tgtgacgaac ataccgatga cgacgtgtgg atatttcaag tctttgaaaa tctgtttggc
    17041 agaaaccatg ttttcttttt tcactgggac aaatttttca tggacgaaaa acagactcaa
    17101 caagaagacg aaaaataaga tgatccctgt aatgaaaaag gtagggcgat agccaaacgc
    17161 tgaagcagag atcccgccaa gaagcggtcc aagtaatgtt cctgtaacag aaccagttgc
    17221 taaggttcca agaacttgac cacttttttc ttttggcgtc ccagttgcga caagggcagt
    17281 ggcattactg atataaccag aaaaaatccc ttgaagcaga cgcaatgcga ctaattgata
    17341 cacactagtc acgcaaccca tcaaagaaat gacgattgcc attcctaatg aagcacgcaa
    17401 cagcatcaat tttcttcctt tttggtcggc taattttccc caccaaggag agataagcgt
    17461 agtcaccaag aaagtagatg aaaaagtcaa tccgctccaa aagttcaatt gtgacgtact
    17521 ataattacct aacgtatcta tgtaaagtga cataaaaggc atgactaaac taaatccgat
    17581 accagccata aatgttccaa accataagac aaacaagttt tgttcccaag tttctctttt
    17641 cctaaataat ttttccttta ttcttgcagc caattagact ccttctttct gaaaattttc
    17701 atctacagct ctttattata aactacaata tgtagtttat caatgaaagt ctcttttttc
    17761 tctttctttt tcgtggtaaa ctgaaagagt gaaggattta ttttatgaga ggaaacatgg
    17821 aaatgaaaaa aagaaatctg tctcaagaga aaatcatcga ctgctttcga gaactagcag
    17881 aagagatgga tgttcagcaa ataacctttc agcatttagc caaacgcttg gatatcaagg
    17941 ctccctcgct gtataaccat ttcaaaaata ttcgtgatgt caaaacagcg ctaacagcga
    18001 aacttctgca ggaacttaat gaccagctgc gacgggctct tgtgggaaaa agtggtcagg
    18061 aagcactgca gatctatgca gaaacttatc gatcctttgc tttttcaaat caagcagtgt
    18121 atgagttact gatcagtgta ccgcatacca atgaagctgt tttattagat ggaatccatg
    18181 aaacgaatca gatcattttg cagatatttg aggcttttca attaacgaaa gaagaaaaag
    18241 ttcatcgaag cagggaactt cgtagtatga tccacggtta tctttcctta cgttttttag
    18301 gatactttac aaaagaacca acaatcgatc cagaagacag ctatttttgg atgatcaata
    18361 actttatcgc tactttgcct taaacaatca gattcatttg taacaatttt aagatgttca
    18421 ttaaatgacc cttttataag agaaaattct tgcaactttc ttgaaaagtg actaagatga
    18481 gtctagaaaa gctgaaagaa ggagcacgag tatgtatcaa gtaattacca tgttcgggga
    18541 caatgagcct tggtggtttt ttgaagactg ggaagaagat attgaagaag aagaaacatt
    18601 cgagtctttc gaagaagcac gacaagcgta cgaaaaacaa tggaacgaaa tccatcaaaa
    18661 ttatgaatat atcaatgcaa aaagtaactt tctcagcgcc ttttggaatg acggagatga
    18721 gcgctggtgt gaagagtgtg acgatgattt acagcaatac aagggacttg cgttgttgaa
    18781 aaatcatcag cccatcacag tagaaagcag aaaggaattt tatgaaacaa ctaattctag
    18841 cggaaaaacc aagcgttgcg aaagacctaa gcaaggtgct tggtgctaat caaaagcaca
    18901 aaaattatta tgaaggaccc aaggtgatcg ttacttgggc ccttggtcat ttattaggat
    18961 tgaaaatgcc ggaagatctg aataaggaat ggcagagctg gcaaatggac acgttgccaa
    19021 tgatccctaa aaaactagga atcaaaccac ttcctaaaac aggacatcaa ttaaaagcaa
    19081 tcaagcagct ggctcagcga aaagatgtct cagaagcagt cattgcgaca gatgccggaa
    19141 gagaagggga acttgttgct cgctggatct tagagtatgt gcatttcaat aaaccagtga
    19201 agcggttatg gatctcttct caaacagata aagcaatcaa aactggattc aagcaactaa
    19261 gacctgcgaa agaatatgat gcattgtatg aatctgctct tgcccgggca aaagcggact
    19321 ggctggtagg attgaatgtg accagagcct taactgtgaa gtacgcggat aatttatcag
    19381 caggccgtgt gcagacaccg acactagcat tagtgagaga ccaagaaaag aaaatcgagc
    19441 agttccgtcc acaaacgtat ttcacgatca cgttgcaagc tggaaaagaa caagccaaaa
    19501 tgcttcaaaa aaatcaattt gctttaaaaa cacaagaaga agcacaaaaa cttgttcaat
    19561 tgatcagtac aagcaaagga actgtcacag aagtccaaga aaaattaaaa acggaatctg
    19621 cgccattgcc ttatgattta acagagatcc aaagagaagc caatcaacgc tatggctatt
    19681 ctgcaaagaa aacattaagt cttgtacaaa gtttgtatga gacccataag atcgttactt
    19741 atccgcgtac agacagcaaa tatctgacaa atgacatgaa aagtacgatg aaagaacgat
    19801 tgcaagcagt cagcgacttt gctcctgagg tcaagcagta tttgaaaaac ggagccatcg
    19861 tccaacagac aaaagtattc caagacagta aagtgaccga tcaccatgca cttttgccaa
    19921 ctgaaaacag agcacgttat gaaaaattaa gtaatgaaga gcgaaaaatc tatcaaatga
    19981 ttgtctctcg ttttttagga ctgtttgctc aaccccataa agtcagccaa acaaaagtta
    20041 cggttgaatt tggtaaagaa cgattcattt ttcggcaaaa tcgtgtcgtc caagcaggat
    20101 ggaaaggcga aactgaaact gagacggaaa cagtcaaatg ggaaaaagga atgagaatca
    20161 atcccgattt cgccatcaaa aaagaactat ctgcaccgcc taaaccattg tcagaagcaa
    20221 gcttgcttgg tcaaatggaa aaatacagtc tgggaacccc agctacgcgt gcagagatta
    20281 tcgagaaact aatcaaatct gaactgatgg aacgtacccc tcaaggactg caagtatctc
    20341 ctaaaggtaa gcaattatta gtattggtaa atccctcttt agtaacacca gatttgacag
    20401 aaagctggga aaaagacctt gaagctattg ctgcaggaaa gaaacaagca ggaaccttct
    20461 tgaatggaat cgaaaaagaa acaaaacgct tggtgaatga gatcaaatca agcaaacaag
    20521 aatatcaaga tttctcgatt acccaaaaga aatgcccaga atgtggggcc aatctgcgcg
    20581 agaaaaacac acgtgacggc aaaatctatg tctgcaccaa ttcagattgc aactaccgca
    20641 gaagaaaaga tccaaaagtc tctaatcatc gatgcccgca atgtcaccgg aaaatggaaa
    20701 tcatcgaagg taaaaacggt gcttatttcc gttgtaaata cgatggaacg acagaaaaat
    20761 tgcttgataa aaaagagcag aagaagaaaa tgaccaaaca tgaagaacga cgcttgctga
    20821 aaaaatatgc acaagcagaa gaaccagaag aaagcccatt agcagcagca ctaaaagcag
    20881 caatgaagaa gtaataagat atgaaagagg ttgtgataga agtggtcagc ttcaagaaat
    20941 aagaaggaat ttacgaaaat tgcttctcaa atttttgtga aatttcggct tatttccgaa
    21001 gaagctactt ctggaacacc atttattcgg aaaaaaggac tgtgacaaga cttttgtcac
    21061 agtccttttt catttaaaaa aatgtttact tcatttgacg tatattattg gtgaggcttc
    21121 aattcatttg gcttcacttt ttctgtttct cttatgatat aaacaggacg ctgtttcgtt
    21181 tctaagaaga ttttcccaat atatttcccg atgattccaa gacataacaa ttggattcca
    21241 ccaatgaaca ggaagatcga gaccatggaa ggccatcctg atgtaggatc accaaacaac
    21301 aatgcccgca aaataatgaa caaaattgca ataccagaac cgacacaaga caaagcgccg
    21361 ataaatgaag caatcgttaa cggtgcatcc gagaagttca cgataccatc aatcgagtag
    21421 ttgaataatt tccagaagga ccaagatgtt tcgccagcca cacgttcgcg gttttcataa
    21481 gaaatatatt ctgttttaaa tccgacccag ctaaataatc cttttgaaaa tcggttgtat
    21541 tctgttaatt ctaggacggc atccaccatt tgacgagtca tcaagcggaa atcacgagcg
    21601 ccatcgacca tttctgtatc gctgatttta ttgatcaact ggtagaattt tttcgcaaag
    21661 aaactgcgta tcgcaggctc gccttcacga gtcgaacgcc gggtgccgac acaatcgata
    21721 tcagaagtag tgatccggtt gatcatctca ggaagcagtt cgggcggatc ttgcagatca
    21781 acatccatca cggtcactaa atctcctgta gaagcttgca atccagcgta cagagccgct
    21841 tctttcccaa aatttctgga aaatgagaca aagcggacat aaggataagc tgaggctagc
    21901 ttcttgattg ctgctaacgt accgtctttt gatccgtcgt caataaacaa atattcgaac
    21961 tcatgggcac ctttgaattt ttcaacctca tcaaaaaaaa gaggaacagt tttttcttca
    22021 ttaaaacatg ggacaacaat tgatactttc atcgtttcta tcctttcaat cgtatgttta
    22081 tatatggttt acattcaaaa tttaataaac cttaaataac acctttaaaa tttgatttta
    22141 cgtaaaagaa caggtattct ttttgtaaac taacgtattt agtttaccat gtttcctcgg
    22201 tttatcaaac ttttaagaac aatttttatt agttggcaag tagttttgga tagagaaaaa
    22261 ggaggaagtt ccagtctatt gactaggagc aaacaaaatg aaaatacaca cacctatcgg
    22321 ctttttatgg ttagatgcag atgaatccgg attgactgct gtatcttttc agccaatttc
    22381 agaaagcgaa tcagcgaatc agcgaatttt aacgcgcaca caagaacagt ttgaagaata
    22441 ttttgcggga aaaagaaaag aatttgatgt tcctttatct ataaagagag gtacgccttt
    22501 tcagcaaaat gtctggaaag ctttgtcgac cattccttat ggagaaatcc gaacgtataa
    22561 agaagtagcc gttgctgttg atagtccgaa agctgtgcga gcgattgggc aggcaaatcg
    22621 aaccaatcca ttgccaatcg ttattccttg tcatcgagtg atcgggcaaa atggaaaact
    22681 gacaggatat atgggaaacg caatagatgg ggttgaaatc aaacgccaat t
//
LOCUS       DAFLWC010000048        22194 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.049, whole genome shotgun sequence.
ACCESSION   DAFLWC010000048 DAFLWC010000000
VERSION     DAFLWC010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22194
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.049"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            259..2094
                     /gene="tdc"
                     /locus_tag="L1V17_001673"
     CDS             259..2094
                     /gene="tdc"
                     /locus_tag="L1V17_001673"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBN1236443.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            2399..3877
                     /locus_tag="L1V17_001674"
     CDS             2399..3877
                     /locus_tag="L1V17_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1236444.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            3843..5174
                     /locus_tag="L1V17_001675"
     CDS             3843..5174
                     /locus_tag="L1V17_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1236445.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            5288..7840
                     /locus_tag="L1V17_001676"
     CDS             5288..7840
                     /locus_tag="L1V17_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HBN1236446.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(7847..9286)
                     /locus_tag="L1V17_001677"
     CDS             complement(7847..9286)
                     /locus_tag="L1V17_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1236447.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            9632..9994
                     /locus_tag="L1V17_001678"
     CDS             9632..9994
                     /locus_tag="L1V17_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HBN1236448.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            complement(10181..11038)
                     /locus_tag="L1V17_001679"
     CDS             complement(10181..11038)
                     /locus_tag="L1V17_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1236449.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            11158..12069
                     /locus_tag="L1V17_001680"
     CDS             11158..12069
                     /locus_tag="L1V17_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBN1236450.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            12076..13727
                     /gene="mdcA"
                     /locus_tag="L1V17_001681"
                     /pseudo
     CDS             12076..13727
                     /gene="mdcA"
                     /locus_tag="L1V17_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
     gene            13829..14128
                     /locus_tag="L1V17_001682"
     CDS             13829..14128
                     /locus_tag="L1V17_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HBN1236451.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            14118..15794
                     /gene="mdcD"
                     /locus_tag="L1V17_001683"
     CDS             14118..15794
                     /gene="mdcD"
                     /locus_tag="L1V17_001683"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HBN1236452.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            15798..16391
                     /locus_tag="L1V17_001684"
     CDS             15798..16391
                     /locus_tag="L1V17_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HBN1236453.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            16415..17491
                     /locus_tag="L1V17_001685"
     CDS             16415..17491
                     /locus_tag="L1V17_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HBN1236454.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            17516..18385
                     /gene="mdcB"
                     /locus_tag="L1V17_001686"
     CDS             17516..18385
                     /gene="mdcB"
                     /locus_tag="L1V17_001686"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HBN1236455.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            18496..19260
                     /locus_tag="L1V17_001687"
     CDS             18496..19260
                     /locus_tag="L1V17_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HBN1236456.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            19749..21842
                     /locus_tag="L1V17_001688"
     CDS             19749..21842
                     /locus_tag="L1V17_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBN1236457.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            21867..22169
                     /locus_tag="L1V17_001689"
     CDS             21867..22169
                     /locus_tag="L1V17_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1236458.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
BASE COUNT         7185 a         3790 c         4729 g         6490 t
ORIGIN      
        1 gaaggacagt cattttattt gtttgttcgc tttttttagg ttatctattt tagaagactg
       61 atttattgaa aaattgttcg cttttttgcg ttgaattatc agaaaaatcc gactttattt
      121 atttttgttt gtaaaaatct acgtggattt gatgttataa aaaaaaaatt ctcatttttg
      181 gcgctatagt gaagaggtgt tacagataaa cacatgtatc tgcaagacat tgaccaacaa
      241 aatatggagg gaagaaaaat gaaagatatg gatatcaagg ccgtctttat aggcgacaaa
      301 gctgaaaatg gaccagttta taaaatgttg ttgaacaaga tggtagatga acatcttgga
      361 tggagagaaa attatattcc ttcagatatg cctgcaatta gcgaaggaga taagctcact
      421 ccagattatc tagccacccg cgaccatatg atagaggtct tggatgaagt cagtcagcga
      481 ttacgcgcag gatcgatccc atggcattca gcaggccgtt actggggaca aatgaatgct
      541 gaaacattga tgcctgcttt attagcttac aactatgcga tgctgtggaa cccaaataat
      601 gttgcattgg aatcttctat ggcaacttcg caaatggaag cagaagtagg acaggatttt
      661 gcttcattat tcaatatgac agacggatgg ggacacattg cagcagatgg ttctattgct
      721 aatcttgaag gattatggta cgcccgttgc atcaaatcga ttcctttagc tgtcaaggaa
      781 gtgctgcctg aaaaagtgaa aaaaatgtct gagtgggaac ttttgaattt atctgttgaa
      841 gaaattttgg aaatgaccga aagctttacg gacgaagaaa tggatgaggt caaagcagct
      901 tcttcccgta gcggaaaaaa tatccaaaga ttagggaaat ggctggtccc tcaaacaaaa
      961 cactattctt ggatgaaggc gttagatatt tgcggagtcg gcttagatca gatggttgct
     1021 atcccagttc aagaggatta tcgaatggat attaatgctt tggaaaaaac aattcgtgaa
     1081 ttagctggac aaaaaatccc aattctaggt gtggttgctg tcgtaggaac gacagaagaa
     1141 ggtcaagtag acagtgtaga taaaatcgtc caattaagag aaaggttaaa agatgaaggg
     1201 atctatttct atttacatgt tgatgccgca tatggcggct atgcgcgttc actgtttcta
     1261 aacgaagcag gagaatttgt gccgtatgct tccttagctg aattctttga agaacatcat
     1321 gttttccacc actgcgtaac gattgacaaa gaggtatatg aagggttcag agctatttca
     1381 gaagcggatt ctgtcacgat agatcctcat aagatgggct atgtccctta tgctgctgga
     1441 ggaatcgtaa tcaaacataa aaatatgaga aatatcattt cttatttcgc gccatatgtg
     1501 tttgaaaaat cagtaaaggc tccagatatg ttaggagctt atattttgga aggatcaaaa
     1561 gctggagcaa ccgccgccgc agtctggaca gcacatcgtg tattgccatt gaatgtgacc
     1621 ggatatggtc aattgattgg ggcttcaatc gaggcagctc aaagattcag agaatttctc
     1681 gatcatctga cttttactgt taaaggaaaa acaatcgaag tctatccatt gaatcatcct
     1741 gattttaata tggtcaattg ggtattcaaa gaacaaggct gtacagattt gaacgctatc
     1801 aatgaattaa atgaaaaaat gttcgatcgg tcttcttata tggatggcga tgtttatggt
     1861 gaacggttta ttacttctca tactacattt acacaagaag attacggtga ttctccgatt
     1921 cgttttgttg aaagaatggg tctaacgaaa gaagaatgga aaaaagaaca gaaaatcact
     1981 ctgctacgtg cggctatcat gactccttat ttgaatgatg atcgaatttt caatttttat
     2041 acaaaaaaaa tcgccaaagc aatggaaaag aaactaaacg aaatcatcca atagaactga
     2101 tttttgtgtg aaagaataac aagagacata tggagaacag acaattattt gcttcatcaa
     2161 aacaattgta tttccccctg tttttcatat attcctcgcc aagatattct tttttataaa
     2221 acgttctata agttggatcg ttcgtttcat gtatcaaacc cagttcacta agatcgttca
     2281 atggatgttt cggtgatact gggttttgta ctgaatcgat gaaaccttgt catttctgtt
     2341 cttgaacaaa aataaaagaa aacaaaaaca tatgtcgcta ttgaaagaag gaataaagat
     2401 gaaagatact ggttcatcaa agcaaatcac gaccatgacc tttatcggaa tgacctgcgc
     2461 ccttgtagca agtgtacgaa atattccaga tgtagcagca acgagctgga cgatgatttt
     2521 ttacatgctg gttgcagtat tattgtacgc ttttccaatc tcattgatct ctggtgaatt
     2581 tgctggaatg tttccccaaa aaggtggtcc agaactttgg gtatcgaatg ctctaggaaa
     2641 aaaatggggg ttcgttgtct catggctgtt atgggtccaa atgtttcctg ggatggtgat
     2701 ggtcgcttca gcactcgctc cgttgtttgg taatattatc gataatgtgc cgcttggttt
     2761 gaacagcaaa tttacattag ttgtcatttt agtcgtttat tggatcatca cttttttgaa
     2821 tttgaaattt gatatggcaa aaatcggcgg aaaagtcggt gtttggttag gattgtacgt
     2881 gcctttgacg atgatgctct tattagggtt tgctgcgtgg atcaaagttg ggatcgtacc
     2941 aaccggaaca ttaggcagtt tttcatggga caaattaata ccagatacta cgactgcatc
     3001 ctcatttgtt tattttgcgc cgatcatgtt tatttttact ggtatcgaaa tgtcctctgt
     3061 gtatatcact cgattggaaa atccagttaa aacgtatatt cgcggagtat ttgccgcgtt
     3121 aatttttata tttttcgtca atattttgaa tgctttagtt gtagcaaatg tcgtaccaaa
     3181 aggacaaatg gaattgaata atatcgcgca atctatttcg atttattgcc aaattcttgg
     3241 tttgccacat cttattgtga atctgtttag tttacttgtc ttcattggtg tagcagtcca
     3301 attatctgct tgggcctcag gaccagcaaa gacagtgaca gaaagtgcta gaaaaggtgc
     3361 gtatccacca aaattcaatt tttggaagac gaatcaattt gacgtatcca aatccgttat
     3421 tttgactcag tctgtcatta tctcaatctt tgcacttttt tatttgctga ttcctggcgt
     3481 caatcaagca tttttgatgc tcgtaaattc aactactgtt atctactgta tcgtctatgt
     3541 catcatgggg atcgcagttt tgagattgcg ttatacacat gcaaagttga atcgaccatt
     3601 tagaattgga aaaaaagaga aaaagagcaa tcttggagtt tggactgtcg ttattgtttt
     3661 atttgcggca atcggatttt ctgtcggact gacgatgaaa gctggaacat ggatcaatct
     3721 aattgcagtc acagccatca gtgtcatttt gtttgtagta ccactctgta ttgaaaaaat
     3781 aaagaaacct tcttgggaac aggaagtcgc catgctgctt gaaaaagaaa aaggtgaact
     3841 tgatggaaaa accggcaatg aaacggactc taactaatcg aaatatccag ttaatcgcat
     3901 taggtggcgc aattggaaca ggattatttt taggttcagc aaaggcaatt gcatcagcag
     3961 ggccagctgt tattctcgtt tatttgatat gcggtttggc tatttatggt ttgatgcggg
     4021 ccatgggtga tttattttta gcaaatagta catttaactc tatcagtgat ttcgttgact
     4081 attatttagg caaaaagtgg gcattttttg tcaattggac ttattggctt tgctggcttg
     4141 gagctggact tgcggaatta acagcaatag gattgtatat ccatttctgg tttgtacatg
     4201 taccagcttt gataagcgga ggtagcgcac taatgatctt aatggcagtc aaccttgttg
     4261 cagtcaagtg gtttggtgaa ttggaatctt ttttctcaat catcaagatc ttggggattt
     4321 tcctttttat cttattgggt ataggattga gtgtctcaga ttttcatacc cagtctatcg
     4381 gaatcaaaga aaattttgga cagatcgatg aattactacc gtttggcttt gctggaatgg
     4441 tagtctcatt tcctatggtt ttattcagtt ttgctggaat tgaaatgatc ggcttaaccg
     4501 ttggcgagac aagtgatccg caaaagaatt tgaaaaaagc aatcaactgt ctgccttggc
     4561 gtattctctt tttctatata ggaacgattt tgtcgatttt atttgttgtt ccatggcatt
     4621 gtttagattt aaaagaaagt cctttagtga ctatgctgca agtgatccat tgccaaggcg
     4681 gagcagcaat tgtcaatcta atgattttgg ttgcttcttt gtcctcagca aatagtgcag
     4741 tctacagtac tagcaggatt ttatatcaaa cagcaaaaga aaaaagtttg ccccattggt
     4801 tttgtgcgct ttctaagaaa ggcgtacctt tacacggtat tttaattaca ggaatgttat
     4861 tttttgccgg tctttgtcta catttttttg tagctgatag tcgattgttt tttcagcttt
     4921 tggcaggcat gacaacgagt tgttttctat ttgtgtggtc ttcgatcttg tgtgcacatg
     4981 ttcaatttat taaagaaaag aaacggaaca ctacacaaag atataaagat cttgctttgt
     5041 tggtgttttt tacttcaatt gctttcagct tgttattcga aagcacgaca cgctttattc
     5101 cttttttatt ggttatctgg tttgtattct taaattttgt atataaaaga ataagcaata
     5161 gaaatatcag ttaggcccag atacattttg caaaacgaat tatttcagac ccccctgaaa
     5221 taatcgatac gcctgaaaaa acttccctgc gtataataac agtatcaatt aaacaggagg
     5281 ggataggatg aactggtaca gattgacggt agaagatgta ttgaaaaact atcaaacatc
     5341 aacagaaggc ttgtcgcaag aagaacgaca gaaacgcctg actgatcaag gatataatga
     5401 aataaaagca aggcagcaga caaaacgatg gaaaaaaata gcaaagcatt ttactgatct
     5461 gctgatgatc gtgttgatca ttgcctcttt tttgaaattt gcttctagtg aatatattga
     5521 aggaagtatt attttattcg tagtgatcgt caatggactc gttagttact ggcaagaaag
     5581 aaaagcggaa gaatcattga atggtttgaa gcagctgatg ggacaagaag cgatagtact
     5641 atcaaacggg atgcaagaaa aaatccctgc gaaagaactg gtaaaaggag atgtcattgt
     5701 cttacgtgcc ggagatgtcg ttccagcaga tatccgatta atcgaagcac atgatttatt
     5761 agtggaagaa tcgattttga cgggagaatc agaagcatct gaaaaaagtc atgccgtttt
     5821 gacagaagaa gaatcgatcg gcgaccagaa aaatatgggt ttttcaggaa cgcttgtaca
     5881 atctggttct gcagtcggtg tcgttgtaga aacaggaaac acgacagaaa tcggtaaaat
     5941 caatcaagca ttgcaatcgg tcgaacaaca aacgacgcct ctgattaaaa aaatcaaccg
     6001 attaaacaaa caaatttttc aaggcattct ttgtttgagc ctattcttag ttatttttac
     6061 gacatttcga tatggtatgg attggcatat ccttctttcg gctacgattg ctttggtggt
     6121 gtcaatggta cccgaaggat tgccagctgt tttgaccatg attctatccg ttggagtaca
     6181 tgaaatggca aaagaaaagg cgatcatcaa aggacttcct tcggtagaaa cattaggttc
     6241 tatgacagtg atctgttcag ataagacagg aacattgaca aaaaatgaaa tgacagttgt
     6301 ggatgtagct gcaaaagaag aagcctgcgt gttgtccatt atgaaaaact gtcaggaatt
     6361 aaaaacaaaa gaagaacaga aaacagaaaa tttaagtggc aatccgacag aagttgcgct
     6421 gattcgacac acagaaacag ccaatctacc tttgaaaaaa atagaagcaa agattccgtt
     6481 cagttctgaa tacaaatata tggcaacgat gcatgcggag gaaaaaggag cggtgattta
     6541 cgtcaaaggt gcaccagaag tattatttgc taaatcaact ctttcttctg cagaacaaga
     6601 agcatggagt cagacagctg cagaatttgc gagaaaaggt cagcgtgttt taggatttgc
     6661 ttataaaaaa gtagattcga aacaggaact cacgcatgag actttaaccc aattaacttt
     6721 tgcagggatc gccggattga tcgatccgcc aaaagaaagt gcagtcaaag ctgtaaagga
     6781 atgccaacaa gcagggatct cagtgaaaat gattacaggg gatcacaaag acacagcaaa
     6841 agcgattgcg gaacaaattg gcttaaaaca tactgccaaa gttttagaag ggatcgattt
     6901 ggatcttatg tctgatgaag agttgattca gcaagtgcca atagtcgatg tctttgctcg
     6961 aacgacacca gaacataaac tgcgaattgt taaagctttg cagaaaaatg gagaaatcgt
     7021 cggaatgacc ggagacggcg taaatgatgc acctgctttg aaaagatccg atgtaggaat
     7081 tgctatggga atcaaaggta gtgaagtaag caaacaggca gctgatatgg ttttaggaga
     7141 tgataatttc catacgattg caaaagccgt aaaagagggc cggcggattt tggataattt
     7201 gcaaaaaacc atcaatttct tcttgccaac tgcattagct caaggattga tcttgatttg
     7261 ggcacttatg ctgaatcgcc cgctaccttt gtccccagta cagattttat gggtcaatat
     7321 ggtaacgaca atcactttat cttatgcact agggttcgag tcgccagatc cagaaatcat
     7381 gaagcgccca ccaagagatc caaagcaagg aatcctatct ggttatcatt tgtttcggat
     7441 catctatgtc tccctactga tcatggttcc tgcctattta ttggctatgc agtttgaagg
     7501 gcaaagctta cagcaaacca ttcttctgca aaatatcgtc ttagctcaag ctgtttacat
     7561 gatcaattgc agagagttgt ccaagccgtc attgaaccaa ggtcttttgc aaaacaaagc
     7621 gctttttctt tcattaggta tccttgcttt attgcaaggg atggttattt ttctaccagt
     7681 cggccagcag ctgatcggta cagtaagttt aacgatgaca caacagttat tgattggagc
     7741 aaatgtgatt cttctattct tagttgtaga aatagaaaaa gggatcatga acaaactgtt
     7801 tcgcaaaaaa gaaaaaacag ctagagaata cagtcgctag ccgttactat aaaaaagttt
     7861 tgaaagtgag ttcagtcaaa cgattgagct catttttcgt tggaatagaa gaaatgtata
     7921 caatagggat atctagagaa tctagaggga aattggaaat caagatatct gttttttcaa
     7981 aagaaatagt ggaaagatcg gttagttcga taggtaagaa gcagacacgt tttcctaagt
     8041 aatcttttaa ttcctgctgc aagaacgcct tccatgaagg ttctccttgg aaaataaaat
     8101 agacattgaa caaattcggt ttgatagaaa aaatcgtttg ttggatcagt agagacaaga
     8161 gttggagaaa gtaatttggt tcattgattt ctatttcttt ttttagatcg ttcagtaaat
     8221 tctctttctg ttgatacaag tgtgcatatt gctgatcata tgtttctaaa aaacgatggt
     8281 attgacggtc caatgcttca atcaatatcg gcgattcatg atattttaat atgaggagag
     8341 ccaagttatc agtcagagat gtttttttta gttgatcaag agacagctct gaagctagtt
     8401 cctctacaaa cgtttcgagg acctctaaaa atggagaatg atgcaggcag cgagcggttt
     8461 cttgtccata gttattgttg taattccaac tttccagaaa gcagaaagaa gcaaaagaaa
     8521 gctcagtgtc tttaagataa ataccttccg ttaaatacaa ttttttcaat gcagagtcat
     8581 acagggagga gagtgtgctg ttggtatgga tagaagaatc taatcggcaa ttcgctttta
     8641 tacggatcgt attgataaag aaccaacatg ttccgaaaat ctcttctgtt tcaaccgcta
     8701 gttcagtttg actgaggttt cttaaaaatt gaaaataatg ggattcatgg atcgaataat
     8761 cctcgaaaaa atagttgtta tgagtgaaag gaatcagcaa tcgatgataa aaagtacgaa
     8821 tcgcacgctc ttttccaaga atacaagctg tatatttcgt caaatcgatc tgcaagtcgt
     8881 aacttgctaa acgctgattg attttagtca catgtctttt caatgtccca taagaaagcc
     8941 catggtcggc tagaaaatca gggacagcaa ctttttttgt aaaaagcaga tttttcagca
     9001 gttcgacact gactgattgt ttgaaaaaaa tctcccaaag gtcatttgtt aataaatttt
     9061 gctggttttg caaactgatt cctgcttgat cgctgatgat gtcccagcct tcgggcagct
     9121 gagagcgaat agattgaagg tcagaaaaaa tcgttcgttc ggttgtccct atgatttcag
     9181 ctaattcatt tacggttatc tttgtatgat tcagcaattg ttctactaaa gaaacatgac
     9241 gtcgaatatc tttttcggta atgatttttt tcattagtga atacatcaat cagactccct
     9301 tctattctaa gaatacggag aaaataaacg gtggtcaagt ttcaactgat ttttcaatca
     9361 ttgtttattt ttctggagca tttactgatg ataagaattt catcatgaac ttgaaaaatg
     9421 ataccactaa aatcaaaaaa taggtgggca aacaataata aacattttaa tagtagatgg
     9481 tagcaagacc aacacaggcg gattgaacat ttaagagttg ataaaaaaga aaaatatcga
     9541 agtatttgat tagcaactac ttgtattcat ttttctattc ttacgtggta tctttgaata
     9601 aagcgaatca ataagaaaga gatggaagca gatgctaacg aaaaaagaac taatcgatca
     9661 catcaatgaa acatacaatt tgtctccaga atatattttt aaaaaatttc ctgattattg
     9721 cgtattcaga catcaaaaaa gcaaaaaatg gtttggggtc ctgatgtctg ttccagaaga
     9781 aaaaatctat gatgatgcaa gtgaccatag gatcatcaat attcttgatt tgaaggtcga
     9841 tcctgaactt ggcggaattt tgcgaggaaa agaggggtat tttccagcct atcacatgaa
     9901 taaagaacat tggatctcta ttgatctacg taaaatagaa aagctagatg aactagcaga
     9961 tttgattgat ggaagtttta aatcaacgca atgaatgtct aggacaatag agaagaggtt
    10021 gtgacagaaa tgtttagctt caagaaataa gaaggaattt acgaaaattg cttctcaaat
    10081 ttttgggaaa tttcggctta ttttctaaga aattacttct ggaacaccgt ttgttcgaaa
    10141 aaagagctgc gacaagaatt ttgtcccagc tctttttttt ttattttcct aaataaaatt
    10201 cccgcatcgt ttttgcaatc attttgatca aaggatgatc ttctgtgaag ctagaagata
    10261 aataaattgt tcgtgtcaag ggcaaatctt tgatttcccg caagacgaaa ggatcatttt
    10321 tatcgtaaga ccaagaaact tttgggaaaa agctaacagc taatccttgc ttgacaatag
    10381 aacgtaatgt cgcaggatca tctgtcgtcg aactgatcgt caattcgata cttttcgctt
    10441 caagtgctgc atccagtgta tgacggaagg cgttgctctt tgacagcatc aagatggggg
    10501 tgcgttggat atcttctaat tgcagatgtt cttttttagc aagaggatgt ttcttaggaa
    10561 tggcgacata aacaggttct ttcatgatag gaatattggt catgccaggc ttcatctccg
    10621 aagtgatgta cagtacagga tcggtaatat catctggtaa atgatgttgc atgatcgtta
    10681 attggatatc aggatgcttt tccataaaaa ttcggaccaa gttcggaata gaaacagagg
    10741 ctacctctaa atacaatatg acggaagtaa cgatcttctc attgaccgaa gacaataatt
    10801 tgattccttc ttctaatgtg tctaatgtct tgactgcata tggataaaat tcttctgcat
    10861 aaacggtcgt ctcaatgttt ctgccgctat ggtaaaacaa agggacacct aattcgtttt
    10921 ccaaatgttt gatcgcacgg ctcaaggcag gttgagaaat aaataattct ttggctgctt
    10981 gggtaacatt ttttgtttcg aatacttttt taaaatactg cagatgaagc aatttcataa
    11041 ttatccatcc catccatacc tttttgttat ggttttttct ttttttggca ttttttatta
    11101 tagcagaaat tgactaagat agcagtggaa aaagtaagtg ctgaggaggc gaggctcatg
    11161 agtacaggtt tcttatttcc tggacaaggc agtcagaagt tagggatgtt agcggatatc
    11221 cctgaaatgt acatggaacg tttagaaaat gtgacggggt atcggttagt tgataaagaa
    11281 gaaaactatc aagatacggt ttttatccag ctagcattac tgacaaaagc agtattttat
    11341 ttagatgaaa tggaaaaaaa cggtattcag cctgatattg cagcaggaca ttcgattggt
    11401 gctttttgtg cagctgttgc ttgtcgatct ttgagatttg agaatgcagc ggaactagtc
    11461 tatcaccgcg cagtcttaat gaaagaagct tatccaagcg gttatgcaat gggcgtagta
    11521 gtaggtgtga cgagaagcga agctgaggaa attgtagcaa aaacatttga tcctgaccat
    11581 ccagtttatc tgtcaaatga aaattgtccg atgcaacata cgttatctgg gagtatcgaa
    11641 ggtttatccg ttacgttggc agaagccaaa cggcaccaag cgcaaacagc gaagctgctg
    11701 aaagtccctg tgccatctca ctgtctcttg atgaatgata cggtcaagaa attcaagccg
    11761 tatatgcagt ctgtccatct atctgatgct agatgtttgt atataaaaaa tacggatgga
    11821 agagccactc aggacgcaga agagattcgt aaagatttgt tggaaaacct agctttccct
    11881 gtgcagtgga accaaatgat ggacttggca aaagaattag gaatggatct gacgattgaa
    11941 tttccccccg gcaatacttt gacaaagctg attcatacaa aatttggtgt agataaaggg
    12001 atccgtacga tcaatctaga ccaacatggt attgatgacg ccacgtttct atatcaaaaa
    12061 tggagatgac taattatgga aaaaccaaac cgcaactggg cttctaaacg cgaaaaaaaa
    12121 gcgcagcgat tggaaaaaat cagcaacttg ctcaatggca agtatgtaga aactgaaaaa
    12181 atcgtagaag taatggaaaa actgattgct cccggcgaca aagttgtatt agaaggcgac
    12241 aatcaaaaac aagcaagttt tctttcagaa agtcttgaaa aagtagatgc agaaaaagtg
    12301 aatgatctgc atttgatcat gtctagtatc tcacgaccag aacatttgaa tatttttgaa
    12361 aaaggaatcg caagcaagat cgatttctct tatgctggtg cacaaagctt gcgtgtcgcc
    12421 caaatgattg aagacggcac aatgaaatta ggtgatatcc atacttattt ggaactttat
    12481 ggacgcttat tcatcgattt gattccaaat gttgttttag tagctgcaga taaagcagat
    12541 aaagacggca acttgtacac aggtttcaat acggaagaaa caccaacaat catcgaagct
    12601 gcagctttca aagatggtat cgtgatcgtt caagttaacg aagttgtcga ttctttacca
    12661 cgtgtagata tccctggtga ctgggtagac gttgtcgtga aagcagataa accttatcaa
    12721 ttagaagctt tattcacacg agatcctcaa aacatcacag aattgcaaat tctaatggca
    12781 atgatggcaa tcaaaggaat ctacgcagaa cacggcgtac aatctttgaa tcacggtatt
    12841 ggattcaata cagcagctat cgaattgtta ctgccaactt atggtgaatc actagggtta
    12901 aaagggaaaa tcgcgaagaa ctgggtattg aacccacatc caacgatgat tccagccatc
    12961 gaatcaggtt gggttgaaag catccatagt tttggtggcg aagttggtat ggaaaaatat
    13021 attgctgctc gcccagatgt cttttttgtc ggtaaagacg gcacgatgcg cagtaaccga
    13081 acattatcac aagctgcagg acaatatgcc atcgatatgt ttatcggttc aaccttgcaa
    13141 ttagattacg aaggaaactc ttctaccgta acaaaaggac gtttatctgg ttttggcggt
    13201 gcgcctaaca tgggacataa tcctggcggt cgtcgtcatt ctacaccagc atggcaatca
    13261 cttcgcgaca atgatgatcc attagggaaa ggccaaaaat tagttgttca aatggttgaa
    13321 acatatggtt caaataaaaa accagtcttt gtcgaagaat tagatgcact agctgttcaa
    13381 aaacaagcag gcttagccaa tgcaatgcac cagtgatgat ttatagcgaa gatactacac
    13441 atatcgtgac agaagaagga attgcttatt tgtacaaagc aaaaacaaaa gaagaacgac
    13501 aagcagcaat tgcagcaatt ggcggtgtta cacctcttgg aatgactagc acgaaagaat
    13561 cactagatag cttgcgtgca gccggcatcg tgaaattacc agaagatcta ggcatcaaac
    13621 gtagtgaagc gaaacgttca ttattagctg cacaaaccat cgatgatttg atcgaatggt
    13681 cagatggcct gtatgaacca ccaatgaaat tcagaacttg gtcataaaat tggcgagaaa
    13741 aaccttttgt cgccatttac ccagatggaa gaagaaagac gaataagcag aacgtgtatg
    13801 ctctgtttta caaaaagggg agagatccat ggaacaatta gcttataaat atccaacgaa
    13861 acagccgatc aataagaaaa tccatgtagg agtggtcggt tcaggagatt tggaaatctt
    13921 gatgtttcca acagaaaaaa cagaatctac tgtaaaaatt tgtacaggaa gcgatggctt
    13981 cggcgaagta tggaacaatg tattaacgag attttttgat cgttatccaa tttcagcaga
    14041 tatcgtgatc aatgacttcg gtgctacacc aggagttgtg tacctacgat tgacgcaagc
    14101 aatggaggaa ctttcagatg aaaaatagtt ttgtagaatt aaacgccaga gaacgagtga
    14161 acgctctact tgacaatgga cgtgaattga ttgatccatt cgatcaaatc atcgcgccaa
    14221 gtttaccagc acaaggaatc gtccctgaaa gtgatgacgg gatcgttgtc agccgtggca
    14281 cgatcaatgg caaacaagca gtagtaatcg ctatggaagg aaaattccaa ggtggcggta
    14341 tcggtgaagt ttccggtgca aaaatcgttg ctgcacttga acatgtgtta gaagaaaata
    14401 aaaaaggaaa tgagatcttt ccagtcattg tactagatac aggtggtgtt cgtttgcaag
    14461 aagcaaacta cggactgtta tctatttcag aaatcggaaa tgtaatcatt gctctaaaac
    14521 aatatgtacc agtcatcggt ttgattccag gacgtgtagg atcatttggc ggtatgtcga
    14581 ttacttcagc attaatgagt tatttaatcg caacaaaaaa agcgagagtc ggtttgaatg
    14641 gaccagaagt tattgaacaa gaagcaggcg ttcgagaatt tgattctagt gacaaagact
    14701 tgatttggaa tacattagga tctcgtcaac gggtagaatc aaaaatcatt gatgaattag
    14761 tgactgatag tgtagaagca atcaaagctg ctgtcatcgc agcaatggac gaacgaaaag
    14821 acacgcatcg cagtgaaagc tcagcatttt atttatcatt acttgattct ttagatcttt
    14881 caaaaccaat ggccattgac gattacaatg aagcaattgc taaccatcaa gcaaaatcaa
    14941 ttgacttacc agaagtagca gaaggaaatg aaccagctgc agcaagtgtt ggttacgatt
    15001 ggtttgcggc actaactggc atgaaaaatc caacttcttc tattagtact gtgtattatg
    15061 gtaaatcaag taaattcata gaagaagcca tcgtgacatc aatcgtacct gatcctaaaa
    15121 acccgatgta ccgtgtacga aacggtgaag ttggtttagt tgaaggtttc cgcatgggac
    15181 aaattttgga tcacgtttac gaagaagata aagacaaaaa agtgaaacgg ccaatcatcg
    15241 ttgtgatcga tgtaccaagc caagcatacg gctataacga agaattgatc ggtatccatg
    15301 tggctttggc taatagtgct gctgcttatg caaaactccg tcaagctgga catccagtta
    15361 ttggattgat tgcaggaaat gctatttcag gtgcattttt agcacatgga ttacaatcaa
    15421 gccgcttgat tgctttaaac aataaagaaa ttaccgtcca agcgatgtct aaagaaagtg
    15481 ctgcacgtgt gacaaaacgt tcggttgctg aaatcgaagc agctgctgaa aaagttccag
    15541 ctatcgctta cgatatcaat aattatacaa aactaggagc gatctatcat ttcctagaag
    15601 atatcaccga ccaagctgct tcagaacaaa atgtcagcaa agtcatcgaa gcaatcaatg
    15661 aagccattca agatgtccgc aatacaaatg acacgatgct gacaaatcga tacacaaacg
    15721 aaacagccaa aacattcgga cgtgtcgaaa caaataaagt ccgtgccaaa atggacgaag
    15781 aatgggatgc ataaaaaatg attcaagcac atgatattgt cctttttgat aaacatgaaa
    15841 tagaagggtt caccttgcct gaatgggtcg ttctaactga aaagatgttc ggaacagttc
    15901 gtcgtgcgtc gacggatcac gcagaaatac taccgattgg tttacgtgga cctgcccgca
    15961 atcagagatg gtcaacagaa atctcaaaac atgccgtcaa acaagtcatt catccgtggg
    16021 acatcatcga acaagaatcg tatagacaag agaaaatcat ggattatcct gtttatcagc
    16081 aatttcatgc tgctagaaac atattatcag gatgtaaatg gggaatcggc ggcagcttag
    16141 gatttgaatt atcgactggg attccggcag taaaagaaac cagtgatttt gatttgctgc
    16201 tgtacgcaaa ttcaccgatt gaattgccaa ttcaggtaat tcaatcgcat cctgcttttt
    16261 ttgagcaatt cgatacccaa gtagtgactc ggcaaggcgg tttttcacta aaagagtatt
    16321 tgagagagcc agagaaaaaa attctattga aaacagtcga aggacctaaa ttaaccaaag
    16381 aactttggta ataaagaaaa agagagagaa agagatgttt gaaaacaaaa aaatcaaaat
    16441 caacgtaagt gacttccaga aagtatcagc tgtaacggct gttatgatgc aaacgatatt
    16501 gagctttgct ttggcaaaca gccacagcgc aacaaataca gcttttcttg gtacctttta
    16561 cgtcatcgtt aaatacacag caccaatgtt tatttttgca attgtttata atatggtaaa
    16621 aacaagtcag catttgtctt attgggaatt tttgaaagaa aagttttttg aactagtcgt
    16681 tccgtatctt ctatggacga cggcttatct ttggctattt ccagcagtcc aacaacaaac
    16741 tccgtatacg gatactgcaa gctttttact gaaatatgtc acaggtgatg gagcgcctca
    16801 tttatggtat accgttatga tgctgcagat ccaattgttc atgccgtttt ttgtttggct
    16861 cggttacaaa gtatttgcta ataaaaaata tgtatggcca gtattgattg gttcaacgat
    16921 tttatatgtc gcatggtatc tgttctatca aacacaagta ttgactgggc cttatcatga
    16981 cagctggtac ttattagatc ggtttgttgc tagtttcatg atttatgggg tagccgcatt
    17041 tgtttatcac gaaaaagtct atcaatattt ggacagagta cgttatcttt tcttacctgt
    17101 tgccttagtt atcgcgttct tttctgtccg ttcattgctc gcacatccag gagacttgag
    17161 ctttgcgaat gcaccttact tgaatacgat ccaaagttta tacagtttag tcatcatctt
    17221 tgctgtcttc ataggcgctt ccaaaatgat tgtaaacgat tcgccaaaat tgccattgtt
    17281 caaatggttg tctgtttatg cttatcgtac gtatttagcc aatgtatttg ttttccaagt
    17341 actgttatta ttgtttaaag atagttggct gcagttacct tcaggagtca tgattcttgt
    17401 agcttatcta atgacggcaa gttgtgcatt tgctttaagc tggttacttc atatcatttg
    17461 ggtagctatc aaaaaaggtt tcagcaagta atagtaggaa gaaggagtga gtgtcatgat
    17521 aaatgacgaa cgaaaaaaag cagtgactca gcaactcgct gcgttggtag aggaagcatt
    17581 gatcgcagaa gtaacattaa gtccaaaacc tggattagtg gatgcactgg atgcgggtgc
    17641 acattccgat atggactatg ctttatttct taagtctgct aagacgctaa ctcctttttt
    17701 tgaagaaatg gctcaaatag catggcatca tgctattgat caggagttaa gagaaagaat
    17761 tgctgagatt gggcgaaaag cggaaaaggc aatgctgatt gctacaaatg gcatcaatac
    17821 ccataaagga gcgatttggg caatggggct attgatcagt gtcattgcac aaaaaatcag
    17881 tatggaacag cctttttctt tatcgaaaat acttgatgat gtcagcaagc ttgctgcttt
    17941 tcctgataca aaatatcgtc ataaaaaaac cactcatggt catagggtga agcaaaaata
    18001 tggcgtaaat ggtgcatatg aagaagcgat attagggtat ccgcatatca ggcttgcaat
    18061 tcaagcagct aaggagctag ataatgattc atatgtacag aaacaaatgc atatgttgtt
    18121 agttttgatg agttcgctag atgacacatg cgtattgcat cgcagtgatc agaaaacgtt
    18181 agtggaaatg caaaaacttg ctcatgctgc tagtcaaagt gctttaccaa atcgtccatt
    18241 tacagcactg ttgcactttt gtcaggaaaa ccaaatctct cctggaggaa gcgcagatct
    18301 cttgtctgca agcttgttca tgctgaagat agaggaatta tggactgccg acacatacat
    18361 ttgtccgatg ttactcaatg actaaataag acaaaattgc taaaaaaaca gtttatgcat
    18421 ctggttattg actcttcctt ttagcaaggc tatcataaaa atagtttttt gtaataaaag
    18481 ataacgagga agacaatgaa aaaaatcaat tatttagcaa tcattttgtt agtgggccta
    18541 tgtttgtttg ctctgccgac ccaaggattc gctgtcgcgg gtggtcatgg tggaggtaca
    18601 tctagcggtc gaagttcggg cagaggttca tttggtggtc gttcatatgg gggcagttat
    18661 tttggcagtc gttcttacgg cagagattct tatgggtatt atggtccagg tacaggtcct
    18721 tctagttatg agcaaacggg atttcttgca ttagctgttt tgtcagtagg aggggtttct
    18781 gctttttcta tcgtcaagaa taaaagacaa aagaaaaggc tgaaagcgga gatattgtcc
    18841 cgcatgtcag gaacggctaa agaaaagaaa gcacagtttc tggaaatcca aaagatattc
    18901 atgaagatcc aatccgcttg ggaagaagaa actcctgaaa aagccagaag ctgttataca
    18961 gacaagctgt ttgccgaaca tcagaaagtt ctgcaaaaaa acaaagcaga cggtgtaaga
    19021 aatcatacta aaaaaataac tattcaggaa gtaggaaatt atcgacagat ccacgaaaat
    19081 agttttgcca tccgaattga tttcagatgc tgtgattatt cagtcgatcg aaaagatggg
    19141 cgattgatct caggaagtaa gacacaacga cagtattttt ctcagatatg gtattttgat
    19201 ttttctgaga aagaaaaaag atggcaagcc gattttattc agccgattat gctggattga
    19261 caggaaatat ttatgaacgg agttgtgaca aaagccttgt cgcagctcct ttttctgaat
    19321 aaacggtgtg ccagagatag cctatcggca ataaggcacg attttgtaaa atatgggaag
    19381 cgatttttca aaatcgcttc ttatcgctca aggctgaaca tctctgtcac aacctctcca
    19441 ctaaatggtg tttaaaagct tgcatctgcg ataataagaa caaccaaacg aaaaatagga
    19501 agcactattt tagtttagtt gttcttatta cttgatgcag gacagctttt tcacaacctc
    19561 ttttttgtat agatgggcaa aatttttgta ataataggcg tatgtctttt tcgttgagga
    19621 gatgaaaaag catatggctt attttttgtt tgctttgctt actttctttc cacttcaagt
    19681 ggcagaaata tctacttttt attatgtaag cggaaccata tacttgaaat cagaaggaga
    19741 tcatttctat gaaaacaaga acaattgaaa tacttcacag aatcatgaca gcccaatatc
    19801 cagtaaaagc aaaacatcta gcaagtgagt tcaatgtcag tcagcggacg atccgtcagg
    19861 aagttcttga agcgaatatc tggttgagca gtaaaaagct tccggagatc cgtacaattc
    19921 gcaacaaagg ttttttgttg aagctggaaa aggaaaagca agctcgatta gaaactgaaa
    19981 taaaagatgt gaaagacggc tttttgaatc ggcgcgaacg tatttttgat ctagttttag
    20041 ccgttgctta cagccgaatc ccgatccatc taaacaaaaa agaagaagaa tttcaaatct
    20101 ctaaaagtac attagatgaa gatatgagac ggttacgagc aacactggtc agttatggga
    20161 tagagatcgt cagttatgga aagcaaggac tggtttataa aggttcagaa cgatctatcc
    20221 gtacgatgat ctatgatttt atcaatcaga atctgggaat gaccgacttc tttatgaatc
    20281 aagatgcaca attaacaccg gctcaaaaaa tctttctcca ttattttcct ttggtggaaa
    20341 tcaaaaaaat acaggagatc tattccaata agttgttgaa acaagaagat gatatttata
    20401 aaaaacaaat cctgcttttt acattgatct ggatccagcg aatcaggaaa catgaattta
    20461 tctctgccat taattggaaa aatacagaaa taaaagacag tagcttttct gcatttattg
    20521 accacatgat cgaggaattt caattggaca atgtcccgca agtagaaaga aattatcttc
    20581 gtttcactat tgagacgttc aatgctagag atatctccaa ttcaatcgag tgggtacaag
    20641 ctcaattact aacgatccaa ttgatccaat ttgtagagaa cgagacacac gtacctttcc
    20701 atctaaagga agaagcttta ttcgaaaatc tctataagca catggctgca ctgattgtaa
    20761 gaatcaagaa tcatatccaa gtcatgaatc cattgaaaga aaacatccga acaaattatt
    20821 tcccaatcta ccgcgcagtc actcattttg ttcctacgat cgaagaagta attggtggca
    20881 agatactgga ggacgagata gcttttcttg tcatccactt ttcgacgatc gccagtgtaa
    20941 tcaagcgaga cttgaattat gtttataaat cagtcgttgt ctgtaaccat gggatggcta
    21001 ctggaaatct gttagcagag aatctgaaag aaaagtttcc tcagatcgag attactgcag
    21061 ttttaagttc aaaagaaatc gaattagtag ataaattgga tgtcaatctg gttttcagca
    21121 cctttcaatt gaattatcga aataagccgc ttttagttgt cgatccgatt ttaactgaga
    21181 cgaatatctt ggttatagaa gactttttga aaagaaatga agaactacag cggttagagc
    21241 ctaacagtca tgaatcgacg gagttattca ctcaaataat agatgtcatg aaagaaagtg
    21301 gtggccgagt agatcgaatc atctatggca agttagaaaa attattcgaa acaaacaatt
    21361 tagaaatcaa caaaagggag atccagccta tgttaaaaga tattttgacg gacagcaata
    21421 tcatgatcaa agaaaaagcc actacttggg aggaatcgat tgaactagct gctagaccat
    21481 tggttaaaga aaacattgtc gaagagcgct atgtcgaagc gatgattcgt gcagtgaatg
    21541 attacggacc gtatatcgtg attggcaaac acatggcact agcccatgcc cgaccagaag
    21601 atggggtcaa taaattagga gtcagcgtag ctacgattga gcaaccaatc gatttcggta
    21661 atcctgaaat ggatccagta aagattattt tttgtttggc agcagtagac tcctactcgc
    21721 atctgaacat catgaaagaa ctaattgaat tgatcaacaa cgaagagaag ttggatcgat
    21781 tgattgaatg cacaaatatc gaagatttca aacaactgct tttttcagta gttgagaaat
    21841 aataaatgat acgggggaga acaaagatga acaaattgaa cattttattc gtatgcggtg
    21901 caggtttagg aagtagtttt gcagcacaga tgtctgctga ggatgttttg aacaaattag
    21961 gagtagaagc caaactggac cattgtgata tttcttccgc agtttccatg aaaccagatg
    22021 tgatcatcac agcagaaaat tttcgttcgc agttcgaaaa gttcgcagtt gatcctaaaa
    22081 cggcgatgat ctatttgaaa aatattgttt caaaaaatga aattgaagaa aaaatcaccc
    22141 cagttctgca agataaggga gttatctaaa tacaaaaaga aaagagggta aaaa
//
LOCUS       DAFLWC010000049        22052 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.050, whole genome shotgun sequence.
ACCESSION   DAFLWC010000049 DAFLWC010000000
VERSION     DAFLWC010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22052
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.050"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            42..770
                     /locus_tag="L1V17_001690"
     CDS             42..770
                     /locus_tag="L1V17_001690"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBN1236459.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            770..1024
                     /gene="purS"
                     /locus_tag="L1V17_001691"
     CDS             770..1024
                     /gene="purS"
                     /locus_tag="L1V17_001691"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HBN1236460.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1026..1697
                     /gene="purQ"
                     /locus_tag="L1V17_001692"
     CDS             1026..1697
                     /gene="purQ"
                     /locus_tag="L1V17_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HBN1236461.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            1698..3920
                     /gene="purL"
                     /locus_tag="L1V17_001693"
     CDS             1698..3920
                     /gene="purL"
                     /locus_tag="L1V17_001693"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HBN1236462.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            3905..5344
                     /locus_tag="L1V17_001694"
     CDS             3905..5344
                     /locus_tag="L1V17_001694"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBN1236463.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            5367..6419
                     /locus_tag="L1V17_001695"
     CDS             5367..6419
                     /locus_tag="L1V17_001695"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBN1236464.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVQESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            6416..6994
                     /gene="purN"
                     /locus_tag="L1V17_001696"
     CDS             6416..6994
                     /gene="purN"
                     /locus_tag="L1V17_001696"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBN1236465.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            6991..8526
                     /gene="purH"
                     /locus_tag="L1V17_001697"
     CDS             6991..8526
                     /gene="purH"
                     /locus_tag="L1V17_001697"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBN1236466.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            8542..9816
                     /gene="purD"
                     /locus_tag="L1V17_001698"
     CDS             8542..9816
                     /gene="purD"
                     /locus_tag="L1V17_001698"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBN1236467.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            9938..10852
                     /locus_tag="L1V17_001699"
     CDS             9938..10852
                     /locus_tag="L1V17_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBN1236468.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(10985..12550)
                     /locus_tag="L1V17_001700"
     CDS             complement(10985..12550)
                     /locus_tag="L1V17_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBN1236469.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(12543..13994)
                     /locus_tag="L1V17_001701"
     CDS             complement(12543..13994)
                     /locus_tag="L1V17_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBN1236470.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14008..15024)
                     /locus_tag="L1V17_001702"
     CDS             complement(14008..15024)
                     /locus_tag="L1V17_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1236471.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15244..16332
                     /locus_tag="L1V17_001703"
     CDS             15244..16332
                     /locus_tag="L1V17_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HBN1236472.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            16386..17912
                     /locus_tag="L1V17_001704"
     CDS             16386..17912
                     /locus_tag="L1V17_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBN1236473.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            17914..19119
                     /locus_tag="L1V17_001705"
     CDS             17914..19119
                     /locus_tag="L1V17_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1236474.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            19376..20353
                     /gene="guaC"
                     /locus_tag="L1V17_001706"
     CDS             19376..20353
                     /gene="guaC"
                     /locus_tag="L1V17_001706"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HBN1236475.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            20617..22041
                     /locus_tag="L1V17_001707"
     CDS             20617..22041
                     /locus_tag="L1V17_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBN1236476.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
BASE COUNT         7098 a         3724 c         5035 g         6195 t
ORIGIN      
        1 gatgtatttg cttttaatgt aaataaaaag gagagacgta catggagaag aaagaacttt
       61 tgtatgaagg aaaagccaaa aaaatatatc ttacttctga tgagaacttg atttggatag
      121 aatatttaga tcaagcaact gcgttgaatg gcgcgaggaa agaccagata agtggaaaag
      181 gagaattgaa taatcaaatc acaagtgcaa ttttccgtta tctgactcaa agaggaataa
      241 aaaatcattt tattgaacaa ttgtctaaaa ccgaacaatt agcaaaaaaa gtacaaatta
      301 tccctctgga agtggttatc cgaaatattg cagcaggaag tttctcaaaa cgtctaggtg
      361 ttcccgaagg taaagaattc atcaaaccaa tcattgaatt ctactataag gatgaccagt
      421 tggatgatcc atttatcaat gaagagcata tctatttctt acaacttgca aagccggaag
      481 aaatcagtga gctgaaagcc caagcgttgg ctattaatga aattttgacc gaattatttg
      541 ctaaggtcgg tttggtttta gtagatttca agctagaatt tggccggtcg aatggacaaa
      601 ttttgcttgc ggatgaagta acaccggata cttgccgatt atgggatgaa cgtacgaatg
      661 aacatatgga caaagacgtt taccgcagag atctaggtga tttgatccca gtctatcaag
      721 aagtatataa ccgtctatcg gaactaactg aagaaaagga gcgagtatga tgtatttcgt
      781 aaaagtatat gtaacctata aagattcagt gttagatcct caaggggagg cagtaaaaaa
      841 agcagtccat cgtatgggat atgaaacaat cgaagatatc cgaataggaa aatactttga
      901 gatacaactt gctgatgcag aagaaccaat cgatacagtg attgaaacga tttgtgacaa
      961 gctgcttgca aatgtaaata tggaaacata ccgatatgaa atcaaaaaaa tggaggaagt
     1021 ataacatgaa atttgcggtc atcgtttttc caggttcaaa ttgtgacgca gatatgttat
     1081 gggcagttcg cgagatcatg ggcgctgatg ccgaatttgt acggcatgat gagtcctctt
     1141 tagaaggatt tgatggggtt ttactgccgg gaggattctc ctatggtgac tatttgagat
     1201 gcggtgcgat tgctcggttt tctacaatca tggaagaagt gattcgtttt gctgaagaag
     1261 ggaaaccagt attcggtaca tgcaatggat tccagatatt gacagaagca ggacttttgc
     1321 caggtgtact gagacgaaat gagtctttgc attttatttg caaaactgta ccattgaaag
     1381 tcaaccccaa gacggccttt acttcagagt atgaagccga cgaaataatc tatcttccag
     1441 ttgctcatgg ggaaggaaat tatttctgtg acgaagaaac acttcaagaa ctaaaaaaaa
     1501 ataatcagat tgcctttact tataatgaca acatcaacgg cagcgtggaa aacattgcag
     1561 ggattacgaa caaagcaggg aatgtgttag gaatgatgcc tcatccagaa cgtgcagtag
     1621 aagacttgct aggatcagaa gatgggaaac ggttctttgc ttccatttta aaaaacttcg
     1681 gaaaggtgac cgtatagatg aaaacattga aagaaccgac agctgaagag atcaagaaaa
     1741 aaagaatcta tgccgaatgg ggattgactg atgaagaata tcgaatgatc gaagaagata
     1801 tcttaggaag aatgcctaat tatacggaaa ctggactgtt ttctgttatg tggagcgaac
     1861 attgttccta taaaaattct aaaccggttc tacgcaaatt tcctactagt ggacctcatg
     1921 tgttgcaagg ccctggagaa ggcgcaggca tcgtcgacat cggtgatgga ctagcagttg
     1981 tcttcaaagc agaaagtcac aatcatcctt cagccgtgga gccttatgaa ggagctgcga
     2041 caggagttgg cggaatcatc agagatattt tcagcatggg ggctcgtcca attgcgttgc
     2101 tagattcatt gaggttcggc gaattagata atccaagaac gaaatattta ctagaagaag
     2161 tagttgcagg tatcggcgga tacggcaatt gtatcggcat accgactgta ggcggcgaaa
     2221 ttgcatttga tccttgttat gaaggaaacc cattagtcaa tgcaatgtgc gtaggtttga
     2281 ttgaacacaa acatatccag aaagggcaag ccgctggcgt cggtaattcg atcatgtatg
     2341 taggtgcaaa aacaggtcgc gacggtatcc acggagcaac ttttgcctca gaagaattta
     2401 atcaagaaga agaacagcaa cgttctgctg tacaagtagg cgatcctttt atggaaaagc
     2461 tgctgcttga agcgtgtttg gaattaatct tgcatcattc ggattctcta ataggtatac
     2521 aggatatggg agcagcagga cttgtttcat ctagtgcgga aatggcttca aaagctggct
     2581 caggacttat attgacatta gatgaagtcc cacaaagaga aactgggatg acaccttatg
     2641 aaatgatgtt atcggaatca caagaacgga tgttgatttg tgttaaatca ggagaggaag
     2701 aaaaaatcca agaactattt cagaagtatg atctagatgc agtcactatc ggtaaagtaa
     2761 cagacgacgg gcaatatcgg ctatatcatc aaggagaaga agtagcaaat ctgccagtcg
     2821 atgcattagc tgaagatgca ccagtttatc ataaagaaat gaaagaacca gctcgaatcg
     2881 tagaatttca gcagttagct ccttatcagc cagttatcga agaacctgga caagtattgc
     2941 ttgatctgct gcagcaaccg acgattgctt caaaacgttc aatctacgaa acttatgatt
     3001 cacaagtaca aaccaataca gttgtccgtc caggaagcga tgctgctgtg atgagggtta
     3061 gagggacgaa taaagcgtta gctatgacca cagactgcaa cgcgcgctat ctgtatttgg
     3121 atccaaaaat cggaggacaa atagcagtgg cagaagctgc tagaaatatt attgctagcg
     3181 gtggtaagcc cttggcgatc accgactgcc tgaactatgg ttctcctgat aaaccagaag
     3241 ttttttggga attatcgact tcagctgacg gaattgctgc tgcgtgtgaa acgttaggaa
     3301 ctcctgttat ttcaggaaat gtctctttat ataatgaaac ggatggtcaa gcaatctatc
     3361 caacaccaat gattggtatg gtcggattga ttgaggatca taaacatatc actactcagg
     3421 aattcaaaaa atcaggggat ctaatctata tattaggtaa gacgtttgca gattttgatg
     3481 gcagtgaatt acaaaagatg cagcttggaa gaatcgaagg tgtgatccga aactttgatc
     3541 tatccattga aaagagaaac caagagttag tattgacagc catccaaaac ggattgattg
     3601 aaagtgctca tgactgttca gaaggtggct tggcaattgc actggcagaa tcagctttca
     3661 aacatcagct agggatatct gtacagtttg aattgtcctc tgctcaatta tttgcagaaa
     3721 ctcaatcaag atttgtgttg acagtcgcac cggaaaataa gacacgattc gaagaaatga
     3781 tgggagatgc tgctgtttta gcaggtaagg tgacggatga agcgataatc gaaatttcag
     3841 caactgacgg tcagatcaaa atagaaactg cagtagcaag aaagtgctgg gaggatgcaa
     3901 tcgtatgtct tatgaagtga agagtttaaa tgaagaatgc gggatcttcg gtgtttgggg
     3961 tcatccagac gccgctagtg tggcatactt cgggctccat agtcttcagc atcgaggaca
     4021 agaaggtgca ggtatcgtgt ccaatgatcg aggaaagctt aaggggcatc gagatttggg
     4081 gctgctttct gaggtattca aagatcaaag aaaattgcag cagttaacag gagaagctgc
     4141 aatcggacat gtacgttatg caacagcagg caatggaagt gtggacaata ttcagccttt
     4201 tctattcaaa tttcatgatc agtcgatcgg cttagcgcat aatggtaact tgatcaatgc
     4261 tcgttccctt agaaaagagt tagaggaaaa tggggcgatc ttccattcta actccgatac
     4321 ggagatattg atgcatttga tccgacgaag tgaagaaaca gattttttaa ataaattaaa
     4381 aagtgctttg aatgaagtca aaggtggctt tgcctattta ttaatgacag aaacggcaat
     4441 gattgccgct ttggacccaa atggttttcg tccattagca atcggacaaa tgaaaaacgg
     4501 agcatacgtg attgcctcgg aaacttgtgc attagaagtt attggggcac gttttataag
     4561 agatgtccag cctggtgaga tagtgatcat caatgacgaa ggaatccaga ttgattgctt
     4621 tacgaaggac acgcagcttt ctatttgttc gatggaatat atctattttg ccagaccaga
     4681 ttcaaacatc gcagggatca atgtgcatac tgcacggaaa aatatgggac ggaatttagc
     4741 gaaagaatcg ccagtaaaag cagatatggt cgttggcgta cctaattctt ctttgtcagc
     4801 cgcaagcggt tatgcggaag ctagtggaat cccttatgaa atcggattag taaaaaatca
     4861 atacattgcc cgaacattta tccagccaac gcctgagcta agagagcaag gtgttcgaat
     4921 gaaattatct gctgtacgag gagtagtgga aggtaaaaag gtgattatgg tcgatgattc
     4981 aattgttcgg ggtacgacaa gcagacggat cgtccatctt ttgaaagaag caggggcaaa
     5041 agaagtccat gtgaggattg cttctcctcc tttgaaatat ccatgttttt acgggattga
     5101 tattcaaacg cgtaaagaac tcattgcggc aaatcacacg attgatgaaa tcaaagaatg
     5161 tatcggtgca gattctttag gttttttaag tgaagagggt ctgatcgaat cgatcggtct
     5221 ggaaaaagat gctccgtatt caggattgtg tatggcttat ttcaacggag attatccgac
     5281 gccgttatat gactatgaag aaaaatatca ggaatcacta aaagaaaaag tatcgttctt
     5341 ttaaaagcag accaagaagg gagtatatga attcaatggc aaatgcatac gcaaaagctg
     5401 gcgtagatgt cgaagctgga tatgaagtag tagaacggat caagaagcat gtcaaaaaaa
     5461 cggaacgttt aggtatgatg ggcgctatag gaggattcgg cggttgtttt gatttatcgg
     5521 tctttcaatt aaaagagcca gtccttgtct cggggaccga tggcgtgggg acgaaattag
     5581 cagtggcaat cgaagcagac aaacacgata caatcgggat cgactgcgta gcgatgtgtg
     5641 tcaatgatat cttagcacaa ggcgcagagc cgttatattt cttagactac ttagcaacgg
     5701 ggaaaaatga tccgttacgt ttggaaaatg tagtaaaagg tgtagcagat ggatgtgttc
     5761 aaggaaatat ggcgctgatt ggcggagaaa cagctgaaat gcctggtatg tactcaggta
     5821 atgattatga tctagccgga tttgctgtag ggatagctga aaaatctcaa ttattgacag
     5881 gagaaacgat caacccagga gatgtgttgc ttggaatagc atctagcggg attcattcaa
     5941 atgggtactc tcttgttcgc aaaattttct ttgagcagca gcagttttct ttatcatcaa
     6001 aactgccaga attgaaaaaa acacttggcg aagaattgct tgagccaacg aaaatctatg
     6061 tttcttcctt gcttccgctg atcaaagaaa agaaaataaa aggagctgca catatcactg
     6121 gtggagggtt tgtagaaaat atcccgcgaa tgttaccaga atctatggct gcacaaatca
     6181 aacttggctc atggccgatt cttccaatat tcggctgttt acaaaaatat ggtgaaattc
     6241 ctgagatgga gatgtatgaa atcttcaata tgggcatcgg tatggtcctg gcagtccaag
     6301 aatcgaaagt aaaagaaata gtacacgaaa ttgagcaagc tggcgaaaaa gtttatgaaa
     6361 tcgggaaagt gatcgccaaa gaaaaacatc gtgtggtgtt tataggagaa gaacgatgag
     6421 aatcgctgtt tttgcttctg gaaacggaag caactttcaa gcgctagccg attatctatc
     6481 gaaaaaagga ttggaatctt cgattgactg gttgttttgt gatcagcctg aagcatatgt
     6541 tttgaaacgt gcaactgcgt tgagtgtacc ggcagattgt ttttcaccta aagaatttga
     6601 ttcaaaaaaa gagtatgaag aagcaatttt gcataaattg aaagaaaaaa agatcgattt
     6661 gatcgtatta gctggatata tgcgaatcat tggaccggta ttgctgaaaa attatgataa
     6721 aagaatcatc aatatccatc cgtctctttt acctgccttc cctggtttgc atggcatacg
     6781 tgatgccttt gaagctggag taaaagaaac gggtgtcaca attcattata tcgaccaagg
     6841 tgtagatact ggaccaatca tccggcagga aaaagtgaga attgaacagg aggacacgtt
     6901 cgattcttta gaagaaaaaa tccatagagt agagcatcga atctatccag aagtgattag
     6961 tgaaattatt gaaaatggag gctatctgaa atgacaagag cattgatcag tgtatcagat
     7021 aaaactggga ttgtagcatt cgcccaaggt ttgattgaac aaggagtaga aatcatttca
     7081 acaggaggaa caaagcatgc gttggataaa gctgggatca aaacgctttc gatcgaagaa
     7141 gtgacagggt ttcctgaaat gatggatggc cgtgtcaaaa cacttcatcc taaaatccat
     7201 ggtggtcttt taggaagacg cgatctccct agccatatgg aggcaatgga aacggaaaat
     7261 atccaaccaa tcgactttgt ttgtgtcaat ttatatcctt tcaaagaaac gattatgaaa
     7321 ccagatgtcg aaatagcaga agctattgaa aacattgata tcggtggtcc tagtatgctc
     7381 cgtagtgcag caaaaaacca tgaatttgtc acctctgttg ttgatccatc tgactatgaa
     7441 gaagtacttt cagaattacg tcagtatggg catacttcac tttctttcag acaaaaacta
     7501 gcggcaaaag tctttcgtca tactgcggca tatgatgcac tgatcgctca atacttaacg
     7561 gattgggtgg aagaaaaaga accggaaaaa ttgacactta cgtatgaacg aaaacaaacg
     7621 cttcgttacg gtgaaaatag ccatcaagcc gctgcctttt atcagtccgc tcttctggaa
     7681 aaatattcga tcgcagcagc aaaacaactc catgggaaag aactttctta taataatatc
     7741 cgagatgcag atgctgcgct acggatcatg aaggaatatg acgagccaac ggtagtcgcc
     7801 ttgaaacaca tgaatccttg tggtattggg acagcatcta cgattttaga agcgtgggaa
     7861 gcagcgtatg aagcagatcc tgtttcaatc tttggtggga tcatcgtttt gaatcgagaa
     7921 gtagatctgc caacagcaga acagatgcat aagctgtttc tagaaatcat cattgcccct
     7981 tcttatacac aagaagcttt ggaattactg caaaaaaaga aaaacatccg attactgaca
     8041 gtagactttg cgcaggaaga aaatcaaaat cgagaagaaa cggtctcagt cttaggtgga
     8101 cttcttgtac aagatcaaga tctggcaata gaaaatgaag aagagtggaa agtcgtgaca
     8161 aaacgtaagc cgactccagc agaagcaaaa gcattagcgt ttgcttggag agctgtcaaa
     8221 catgtgaaat ctaatgcgat cgtactggca aacgaacgtc agacagtagg aatcggagcc
     8281 gggcagatga atcgagtcgg ttcagtaaaa attgcgattg aacaagcgca agagaaaatg
     8341 gaaggtgcag ttttagctag cgatgcttat tttccaatgg atgattcggt tgaatatgca
     8401 gccaaacatg gtataaaagc aatcattcag ccaggaggaa gcatcaaaga ccaagattct
     8461 attgatatgg cgaataaata cgatctagca atggtcttta ctgatgttcg gcattttaga
     8521 cattagagag gagtcggata aatgaacatt ttggtgatcg gtgcaggtgg tcgtgaacat
     8581 gcaataagta aaaaactttt agccagtccg aaggtggata cggtgtattg tgcgccagga
     8641 aatccgggga tgacaaaaga tggtatcaat tgtgtcgcta tcagtgagcg agatcattca
     8701 gcgttaatcc attttgttaa gaaagaggct attgattgga gtatcgttgg tcctgaagtt
     8761 cctttgttaa atgggatcgt cgatgatttt atggcggaag gattgaaaat cttcggtccg
     8821 acaaaagcag cagctctgat cgaaggttcg aaaagttttg ctaaacaatt aatggatact
     8881 tatcaaatcc cgacagctaa atccagaagt tttgaatgtt acgaaaaagc agcagcgtat
     8941 atcaaagaaa atggtgcgcc aatcgtagtg aaagcggacg gcttagcagc tgggaaaggt
     9001 gtagtcgtgg ctaccacagt gaaggaagcg ctggatgcgg cagaacaaat gttgaaccag
     9061 catcgatttg gggatagtag caaaaaaatc gtcgtagaag agtttttggc aggagaagaa
     9121 ttctcccttt tggcgtttgt ccgtaatacc aaggtgtatc cgatggtcat ttcgcaagat
     9181 cataagcggg catttgataa cgataaaggg ccaaatacag gcggaatggg tgcttattca
     9241 ccagtaccgc aaatttcaaa aaagatgatt gaaaaagctg tggaagaagt tttaaaacca
     9301 gcggctttgg gaatgaaaga actaggacgc tctttcacgg gtgttttata tgcgggtttg
     9361 attgctacga aggaaggacc aaaagtgatc gaattcaatg cgcgtttcgg tgatcctgaa
     9421 acgcaagtcg ttctttctcg gttgaagagt gactttgcgc aagtaatcga tgatttatta
     9481 gagaatcgta cagtagagtt aaagtggcag caagaaggat acaatgtagg cgttgtggtt
     9541 gcagctgccg gttaccccga agaatatgag acaggaatgg ttctaccaga ttttctggaa
     9601 gaagagcttt ctgtttacta tgctggagtt tcctcaaata acggcaaact agttggagca
     9661 ggaggacgtc tttatttagt agaagcatac ggtgagacga tcaaagaagc acagaaaaaa
     9721 atttacaccg cgttaatgga taaaacgaca gatggaacat tttatcgtac agatattgga
     9781 gaaaaagctg ccaatagcga actgatcgtg aagtaaatca gctgcttcca tttataaaaa
     9841 atacaacaaa cataatcgga agcgccgatt ttagtgaagc cttttcataa agagtgtggt
     9901 acacttttgt tgtgtatata aataaggagg agttcagatg aaaaaaattc aattaggtac
     9961 ttctgatcag aaagcagctg cagtgatctt aggctgtatg cgtatcaaca atgcggaaga
    10021 tccagtaaaa gtgattgaga cagcttatga aaacggcatt gatttttttg accatgcaga
    10081 tatttatgga aacggtgaat gtgaagaaat ctttgcagat gctctagcaa aaacatcaat
    10141 caaacgagaa gatcttttta ttcaaacaaa atgtggaatc gttccaggtg tgatgtttga
    10201 tttttctaaa aaacatatca ttgaatctgt agaaaaaagt ttgacccgtc tgaaaatgga
    10261 ttatgtggat gctttacttc ttcatcgtcc agatacattg gtagaaccag aggaagtagc
    10321 tgaagcgttt gatgaattgg aacggtcagg aaaagttcgt tattttggcg tcagcaatca
    10381 aaaaccaatg caaatcgaat tgctgaaaaa atatgttcgt caaccattag tagctaatca
    10441 gctgcaattt ggcttgaaac atactggaat gatcgatcaa gggattcatg tcaatatgac
    10501 agatgaagca agtatcgatc atgacggtag tgtacttgat tattcccgat tgcatgatat
    10561 gacgatccaa gcatggtcac cataccagta tggatttttt gaaggtgtat ttatcgggaa
    10621 cgaaaaattc cctgaattaa accaaacatt agaagaacta gcagctaaat atcaaacgac
    10681 accaactggc ttggcttctg cttggatttt acgccatcca gccaatatgc aagtgatcgc
    10741 cggtacgatg aacgtagggc gaatcaagga aatcgctcaa gcttcagaaa ttaatatgtc
    10801 tcgggaagat tggtacgaat tgtaccgtgc tgctggaaac attttacctt aaagattgtc
    10861 ataagcaggt caaaagggct ataaattaaa aagacagaat aacttgaaag ctgttttcag
    10921 cttcgagata ttctgtcttt ttttattgca aatggaaaga gtatcattgt acggatttcg
    10981 tttattagtt atttttgttt ttaaggaaaa gctgtgtccg atattctttt ggagaaatcc
    11041 cttgtttttt cttaaataaa taactgaaat agttagggtc attataacca atttcaaaag
    11101 caatatctga aatacgatag tctgattgct gcaataattt ttttgctaat tcgattcttt
    11161 gttctgtcag ataatcgatg aatgtttggt taaacgattg agaaaaaatc gtactgaaat
    11221 gagagggact taatgcaact tgttgagcga cccaagttaa ggacatatct ggatcggtaa
    11281 aattttcttt gataaaatcc aatgcatggt tcaaaattgg ctgatatttg ttccttgaag
    11341 gctgtgaggg cagagcagtt aagaaagaaa tgaacatata aactgtcgaa cggtaaagcg
    11401 agtcgtcggc gctgattgct aagcgttgac tggtggatgt gcaatgaacc atttcttgcg
    11461 ggattttctt ttctttcagg cagacatgct ggagtagctt agtcaagaca aataaacgat
    11521 ataatcgtgt tcgagttggt gtgccttgtg gtttcgtcaa gtgttcgatg tacttagata
    11581 cttcgttttt cgataatgaa gacaaatcaa gtgagaggtc aaagtaaaag acagaatcaa
    11641 ctggaagttt cgcttcttga atcaaatcct catagctgat aatttgttct ttaagggaac
    11701 tggcggtttc aagtatcatc tgcgtgatct caaaagatgc aggtaattcg ctgattcttt
    11761 ctgcgacagg accaatggcg acagaaaaat tatttttttg tcccttttct aattcatgga
    11821 ccaacgtttg ggctacctga taactggtct cgatcacatt ttcttcaaga gaatcaacta
    11881 ttaaaaattt gatgaatcga gaggaaacag cagagaagat cacttgttga ttctccctaa
    11941 ataaaaactt caaataatca ctgagatgag cgtaatcttc aaagtctgta ctgacttggt
    12001 ttgctgctaa taatacggtc atttttttcc ctgctaaaga gcgattgaaa gattcagcaa
    12061 gtttcaatgt ttcactgatc gtaagtgagc ctttgaacaa accgttcaag aaatgatttt
    12121 ttttcaattc gaaaacaaga tcagaagaag tgtgcgtttc tttttgctgc aaatctaaag
    12181 cagttactgc tttttctatt gcttgtttca attcgctact tttaatcggt ttaagcagat
    12241 aatcatctgc ctgtacctgg attgctcctt tcatataatc gaaatcgtcg aatccactaa
    12301 taaatatgag acgagtccaa ggaagtagtt tccttgcttc ttttgaaaaa gtcaacccgt
    12361 ccatgaaagg catttggata tcagtcagaa tgatgtcggg ctgtaagtcg ataattgaag
    12421 acagtgccat ctcaccatct ccagcttcgc cgacataagt gattggataa taagaaccaa
    12481 ggacagttat ttgttcccgc aagttattgc gaatgaggta ttcgtcttcg atgataaaaa
    12541 ctttatacat gtttgtttcc tccaattgtt ttgggagata gagggatcat cagtgtgaca
    12601 gttgttcctt ctcggtattt gctgtcaatc gtgataggtt tttgatcatt tccgtaataa
    12661 agaaggagac gcttgtttac gttgtaaagt ccgtagccga tactgaaatc tgaatcgatc
    12721 cctttggcta actctttacg tatttctgcc agtttttctg cagggatgcc aatcccgttg
    12781 tctataactt tgaattggat catctcatca attttgcatg tggtaatacg aataaatcct
    12841 ttgtgacgga cgtacttcgt tccatggtat acagcatttt caatcaatgg ctgcaagatc
    12901 atttttaaaa tagaaacagg aaaaagtgtt tctggtatat cgatcttata gtcaagcata
    12961 tggccgtatc ttatttttaa gatgactaga taatcattga tatggctaat ttctttttca
    13021 agaggaatcc agtcttgtcc tttgcttaaa gacgtacgaa aaaagccgga aagtgcatgg
    13081 gtcatagtca gagcttcttc aaagcagtct tgttcgatca aagaaataat ggcatccaaa
    13141 ctgttataaa taaaatgggg agtaatctga gcttgcaata cacgaacttc actttgtgct
    13201 aaatggtatt gtttcaaagc gttctcccgt aaagactggt ttagatcttc cgccatttta
    13261 ttcatgctag cggtaagtgt ttgtaattcc agtgtttccg gcagggttaa acgaaagcca
    13321 aggttccctg aagaaagttg ttctgacatc tcgatcagct gattgatcgg ttcttggacc
    13381 tttctctcta aaaagcgacg attctttttc gcatagaaaa aaatggtact aagaactcca
    13441 agttccacta ttgttaatag aatgagcgag cggacaagtg tcgtattttt tttgcttgct
    13501 aagtcgatct ccacacgaac aaaatcttgt aagatatctg acagcagttg agtgacagaa
    13561 tctacctgat tgatgatctc ttcattggta tccataaaat cttttgccaa gatattattg
    13621 atcagctcgt tttgataatc ttccagtgta tcgatcgtac gtagcgatac atctaacgta
    13681 ctaatttctt taagtgtatt tgtattattt ttgatctctc gaatatcatt cctaagttct
    13741 tctaggatat tttcctcatt gaactcatct acggttactt ggccagaaat caagtcccac
    13801 atactttcca aaactttttg atcaaccttc aaagcaattg catctgcttt ttggatattt
    13861 gcgatcgtct gttgataaat caaaagctgt tgcgaatata acagtatgct cagtagcaaa
    13921 gggataacag caaatagaag catggctttg tttgcttggg caaaaatctg ttttatgctt
    13981 aaattttttg tcatgatact tctccagtca ataatttctg gttgggatgt tagctatatt
    14041 ctgctgggaa aagacagtct cggaaataaa aatatcttta ggtaatgttt ttcctgtttg
    14101 aatatttcca aaataacgag taacggtatt ggctacatac cagccgacat caggtttaca
    14161 ctcgactaca caattgacga ttcctgagcg tagcttctcg atcatatctt cttgtccatc
    14221 aatagttaca atgatcaaat cttctccagg tttgattgat gtttctttta tcgcagctaa
    14281 agcaccgtga gtcatttcat cactatggct gtataataca tcgatttcgg ataaatcatt
    14341 tgtttctaaa tatcgtttca tctggtcttt tcctttcatc cgaataaaat caccgacaat
    14401 tcggtgaaca atagtcatcg gaggtttatg gtcgatggtt ccatcttttt ttagggttgg
    14461 tttacgattg attgattcca aaaatccttc ggagcgtagc ttggtcggtg tggagttctc
    14521 tgaaccagca agttctagga ttctgatttc ctgtttcttt gaatttgtga agtgattgct
    14581 gacaaataaa cccgcccgat ttccttctgc tttgaaactg gggccaatgt gggtgacgaa
    14641 aagctcggga tcattcgttt gaatatgtct gtcgacaagt atgacaggga tccctgctcg
    14701 ctttgcttct tttaatacag agtcccaccc ggattcttgc aaaggagtaa aaatgatcat
    14761 atccacttta taggcaatga acgtccgtat atcttggatt tgccgttcct gattcatgta
    14821 gccatttcgg tagagaactt ggtaatcttc tttttcaagc gcagtgataa ttgattcagt
    14881 atgctttttc cgccagctac tctccgttcc tgattgcgaa aaaccaacga ctagtgggtc
    14941 aggtgcttcc tttgtattag gtgtacaccc catcatttgg taagcgatta caacaagggc
    15001 taaaaaaaat aaaacacgtt tcactttaaa tcactccatc tggatttgtt agtactatct
    15061 tatcagataa aagggaaaat caaagtcaaa aggaatcaat cgaaaaaaat ccaagaaact
    15121 taaaaaaatc caagacaaaa aaagtacacc taaaaaattt aaagtaaatc ccataaaaaa
    15181 atcaatgtta acgctttctt tattagctat actcggtgta tcaattgaaa tgggggataa
    15241 aaaatgaaaa acaaatttag aaagattgtt gggactatcg ctattttgac cgcaagcatt
    15301 ctattaagtg cgtgtggcaa ttcaggatct gcagatgata gtacggggta tgtaggaatc
    15361 gctatgccga ccaaatcagc agaaagatgg atcgctgatg ggaacaacat ggtctcggaa
    15421 ttagaaaaac tgggttataa aacagatctt caatatggag aagataaagt agaaaatcaa
    15481 gtagcacaaa tagaaaatat gattacaaaa ggggtagata cacttgtgat tgcttctatc
    15541 gatggttcgg ctttaactga tgtgttagct aaagcaaaag aagcagatat caaggtgatc
    15601 gcctatgatc gtttactgat gaattcagaa aatgtcgatt attacgcgac ttttgataat
    15661 tttggagtag gtgtatcgca agcagcttat attgaagagc acttaggatt gaaagaagga
    15721 aaaggaccat tcacgattga attatttggt ggctcgcctg acgacaacaa cgcactaatc
    15781 aattacaacg gagtgatgtc tgttttacaa ccatatatgg acaacggtca gttggtcgtg
    15841 ccatctggac agacgagttt cagtcaaatc gctacgcttc gctgggatgg ttctacggcg
    15901 caagcaagga tggataatct gttaagcgca aattatactg accaaacatt ggatgctgtt
    15961 ttgtcgccat atgatccaat aagtttagga atcatttcgt cattaaaagg cgtggggtat
    16021 gggagtgaaa gtaaaccttt acctgtgatt actggacaag atgcgacagt tgctggcgtt
    16081 aaatcgatca ttgccgggga acaaacacaa acgatcttta aagacacacg tatcttagca
    16141 aaaaatacga ttgaaatgat caaagcaatc agtgatggag aagaggttcc ggtcaatgat
    16201 actgaaactt atgataatgg ggtgaaaact gtccctacgt atttagcaaa tacagtatct
    16261 gtcgataaag ataattatca agcagagctg atcgacaccg attattataa agaatccgat
    16321 ctgaaaaatt aagaggaacc aaacaaggaa ctaaagagat ctaagtcaga gagaggataa
    16381 gaattatggc ggattgtatt ttaaaaatgg cagatatcac caaaaaattt tctggaatcc
    16441 gagcgttaga ttgcgtgaat ctgatgattg aacgtgggga aatccatgca ttgtgcggag
    16501 aaaacggagc gggaaaatca acattgatga atgtcttgag cggcttgtat ccatatggct
    16561 cctatgacgg ggaaatcttt tatgatggaa agctgtgtca atttaaagat ttgaaagata
    16621 gtgaagaaaa aggcatcgtc atcattcatc aagaattagc actaagtcct tatctttcaa
    16681 taaaagagaa tatttttctc ggaaatgaac aagcagaaag aggcgtgatt gattgggaac
    16741 tgacagaaaa gaaaacatat gaactgctga ataaagtcgg tttgtctatc gacccgaatc
    16801 ttctagtatc ccagattggc gtagggcaac agcaactagt tgaaatagct aaagcattat
    16861 caaaatccgt ccgtctgttg attttggatg agcctaccgc tgcattgaat gaagaagaaa
    16921 gcgcgaattt gctgagattg atccgagagt tgaaagagca aggtgtaacc tccatcatta
    16981 tttcacataa gctgaatgaa atcgtggata tcgcagatcg aatcaccatt ttacgggatg
    17041 gacagacgat tgagacacta gaaaatgaaa tgatcagcga agagcatatt attcgcggaa
    17101 tggtgggcag agatttagtt gatcgttatc ctgaaagaaa accggatatt ggagaagttt
    17161 attttaaagt agaagactgg acggtctatc accctcttga tcacgagcga atcataaacg
    17221 accacatcaa cttgcatttg aaaaaaggag agattgtagg aatagctgga ctgatgggag
    17281 cgggcagaac tgaattcgct atgagtctat ttggacattc ttatggaagc aagatatccg
    17341 gacgtatatt aaaggaaggg gcagagatat cagttaagac cgttccttca gccattgcaa
    17401 acggactcgc ttatgtctcg gaggaccgaa aatctttagg actgaatctg ctgatggata
    17461 ttcgggaaaa cgtgacgctg agcagtttgg ataaaataag tcaaaaagga gtattagata
    17521 aagaaaaaga agtaactgag gcagaaaatt tccggaaaaa gatgcgtata aaaacaaact
    17581 ccatccatca aattgtcagt agtcttagtg gtgggaatca acaaaaagtc gttttatcca
    17641 agtggctgat gacacaaccc gatattcttt ttttggatga gccaacccgt gggatagatg
    17701 ttggggcaaa atatgagatc tacacgatta tcgaagaaat ggcagcaaat ggcaaagctg
    17761 tctgtcttat ctcttctgaa cttcctgaaa tattagggat gtgtgatcga atctatacga
    17821 tgaacgaagg acgtattaca ggagaagtct cgcgagaaga tgcagatcag gaagtcttga
    17881 tgaaattaat gacgaaagaa gaggtgggtt aagttggaac aggcaaaaaa tcttacggat
    17941 aaaaaagaga aaaaactaaa tttgaaaagt agagcagctg atctttttgg tcgctacagc
    18001 atggtgatca ttttagcggg actacttatt gcgtttcaat tgatgacgga tggtattttc
    18061 tggcgtccat tgaatataac taaccttgtt ctgcaaaata gccatatatt agtactagct
    18121 gcagggatgt tattagttgt gctcttaggt catgtggatt tgtcggtagg gtcagtgatg
    18181 gcgtttgttg gtgcaattgc gggcatgatg atggtcaatc gccaaatgaa cccgtggatg
    18241 acagttatcg catgtcttgc agtaggcggg ctgatcggcg catggcaagg tttttgggta
    18301 gcttatgcag ggataccggc gtttatcgtg actttagcag gattgctgat gtttcgtgga
    18361 ctgacacaag ttgttctagg aggccaatct ctagcacctt ttccagctgt tttccaaaaa
    18421 atgtctacgg gttatttacc agacttaagc gaaggaagca gccttcactt cttgacattg
    18481 attttaggaa tgatcatcac gatcgtgtta gttgttggtc aatggcgaac aagaaatcgt
    18541 cggaaaaatc atttatttga agtggaatct ccaacagctt tcttggtaaa ggcggtattt
    18601 acagcagtcg ttgtactagg aataacttat atctttgcct cttatcaagg gtatccgatt
    18661 attttgatca ttcttggttt gatcgttgca gcatatgggt ttttgacaaa taaaacagta
    18721 gcaggtcgac agatttatgc gacgggcgga aatcgaaaag cggctgaact atcagggatc
    18781 aaaacaaagc gaatcacgtt ctgggtattc gtcaacatgg gagtcatggc agctttagct
    18841 ggattagttt tagctgctcg attgaatgcg gcaacacctc aagcaggtac atcgatggaa
    18901 ctggatgcaa tggcggcagt atattttggt ggtgcttcga cttccggcgg cattggaaca
    18961 atcatgggtg cgattgtcgg tggcttggtc atgggtgtat tgaacaatgg catgtcgatt
    19021 ttaggcgtcg gggtagactg gcagcaggca atcaaaggat tgatcttgct tttagccgtt
    19081 gtgctagact tgtataataa gaaaaaacga acaacgtagg agaacgccgg ttattcagaa
    19141 aaaagactgt gacaagacat ttgtcacagt ctttttttcg ctaaaagcga acattcattg
    19201 tttcgtttgt atagactaaa aataatatat gtttttttac cattcgtata aattctcttt
    19261 ttgctcttga tttttttgct taattgagtt aaattacata gggcgctaaa aaaagccttg
    19321 attaaattaa taatgttcgt gttttgctgg atgtgaacat caggaggata atgtaatgaa
    19381 agtatttgat tacgaagata ttcaattaat tcctaataaa tgtatcgtaa atagccgttc
    19441 tgaatgtgat acaacggtca cattaggtaa acatacattc aaaatgccag tagtgcctgc
    19501 caacatgcag acgattattg atgaaacaat cgcagaattc ttagcggaaa atggttattt
    19561 ctatatcatg catcggtttg atgaagcagc tcgaattccg tttatcaaaa aaatgaaaaa
    19621 gcgtggattg attacctcga tcagtgttgg cgtcaagaaa gaggaatatt cctttataga
    19681 gaagttggca gaagaatcgc taaatcctga ttatatcact atcgacatcg cgcatggaca
    19741 tgctaactca gttattgata tgattcagca tattaaaaaa tatttgcctg aaacttttgt
    19801 gattgccggt aatgttggta caccggaagc cgtccgtgaa ttggaaaatg cgggcgcaga
    19861 tgcaacaaaa gtcgggattg gtccaggaaa agtatgtatt acaaaaatca agacaggctt
    19921 tgggactgga ggctggcaac tggcagctct tagatggtgt gcgaaagcag ctcgcaagcc
    19981 gatcatcgct gacggtggga tcagaacaca tggcgatatt gcaaaatctg tccgttttgg
    20041 tgcgacaatg gtcatgattg gttcattgtt tgccggtcac gaggaatctc ctggcgaaac
    20101 aaaagtcgaa aatggaatcg tgtataaaga atactttggt tctgcttcag aattccaaaa
    20161 aggcgaaaaa cgaaatgttg aaggaaagaa aatctggatc caacacaaag gatctttgaa
    20221 agatacacta gtggaaatgc aacaagacct tcaatcatct atttcttatg ctggaggaag
    20281 agatctggaa gccattcgaa aagttgacta tgtcatcgtg aaaaattcga tttttaatgg
    20341 agacacaatc taaaaaataa ataaaatatt aggatgttgt gaaaaagttg tcctgcatta
    20401 agtaataaga acagccaaac aaaaatagtt ctttatatgt tttgtttggc tggaattatt
    20461 atcgcagata caagcttttg aacatcatta ttcagaataa gggactgtga taagattttt
    20521 gtcacagtcc cttatgtttt gcaaaaaaag tttttctttt ttctcgtaaa ttcggtaaaa
    20581 tcaaaagaaa aaatagacaa tagaaaagag aagcttatgt gggaaaaagt agagaaaaaa
    20641 caaggaccga tttatcgtca aattatggaa cagattatga gagaaatcga aaacggaagg
    20701 atcaatcctg gaagtcaact tgaatcagaa cgaaaactag ggcaactttt tggtgtgaat
    20761 cgttccaccg ttgtccatgc attggaagag cttagggagc ttggggtact aacgagcaaa
    20821 cgtggcagcg gatggtttgt taatcagact gaatggggga aattcgctgt tccaagaatc
    20881 gattggcggc aaatgatctc tcctcgttat gagcagacgg actggtatga gcaaaaaata
    20941 agagaagcaa agcagatcca aaaaacatcg tttcttgatt tatacgctag cgagatgcca
    21001 gatgagcttt tgccgaattt tgagtttcct tcttattctc ttgaagaaat cttagcggaa
    21061 gaaaaagaaa tggatctttt aggctatact ccgttacgta acaaaatcaa acggtatttg
    21121 gaaagtaaat ttgaattggc attttccccc aaccagcttc ttgtgactgg tggcggtcag
    21181 caagcaatct ttttgatttt acaaacgatt ctttcagctg gagaggggat agctgtagag
    21241 tcaccttctt ttttttaccg attacctctt ttcaaagctt caggaacgcg tttatttggg
    21301 ataccgatgg atgaagaagg gatcgactta gaaaaactga aagaatcgat ccataaaaat
    21361 aaattgaaag cagtgcttat caacccgaat tttcaaaacc ctacaggaaa agtgatgagt
    21421 caaaaacgac gagaaaagct agtagaattg tgtcgacagt atcggcttcc aattattgaa
    21481 gacgatgtat ttacggatct ttcatttcta aaccaagaag aagtccttcc tatacgaacg
    21541 attgatccgg ataatgtgtt atacgtcggt tcgttatcta gggttttagg aaaaacaacg
    21601 aaaatcggtt gggtgatagg acctgagact tttatctcgc aactagctca agcgcaagaa
    21661 atgatggagt tttcgatgaa tatccttaca caaatcacag tggctaatgt atttaatgaa
    21721 gcaattgatt tgaaaatgca agatgtaaga aaaaagttga aagaaaaaag ccgactgata
    21781 agcgcttggg gagattcaca atcgtttttc aagcttcatt caattttagg tggttactat
    21841 gcctggatta cttgggatgg gaaaaaacta gaccccgaac tagcagaaaa agtagtagat
    21901 atgggtcttg gaattgcacc aagtctactt tttgggcaag atataaatgg aatcagaatc
    21961 aattacagta ggctggatga aaaccaaata ccgttgtttt attcaaagat gaaaattcta
    22021 gaaaagtggt taacagaata atttcacaaa gt
//
LOCUS       DAFLWC010000050        22051 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.051, whole genome shotgun sequence.
ACCESSION   DAFLWC010000050 DAFLWC010000000
VERSION     DAFLWC010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22051)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22051)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22051
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.051"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            156..1862
                     /gene="efbA"
                     /locus_tag="L1V17_001708"
     CDS             156..1862
                     /gene="efbA"
                     /locus_tag="L1V17_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HBN1236477.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2020..2922)
                     /locus_tag="L1V17_001709"
     CDS             complement(2020..2922)
                     /locus_tag="L1V17_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1236478.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2919..3611)
                     /locus_tag="L1V17_001710"
     CDS             complement(2919..3611)
                     /locus_tag="L1V17_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HBN1236479.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            complement(3654..4295)
                     /locus_tag="L1V17_001711"
     CDS             complement(3654..4295)
                     /locus_tag="L1V17_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBN1236480.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4333..4647)
                     /locus_tag="L1V17_001712"
     CDS             complement(4333..4647)
                     /locus_tag="L1V17_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236481.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4635..5987)
                     /locus_tag="L1V17_001713"
                     /pseudo
     CDS             complement(4635..5987)
                     /locus_tag="L1V17_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372436.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
     gene            complement(5984..6916)
                     /locus_tag="L1V17_001714"
     CDS             complement(5984..6916)
                     /locus_tag="L1V17_001714"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBN1236482.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6913..7689)
                     /locus_tag="L1V17_001715"
     CDS             complement(6913..7689)
                     /locus_tag="L1V17_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBN1236483.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7743..10928)
                     /gene="carB"
                     /locus_tag="L1V17_001716"
     CDS             complement(7743..10928)
                     /gene="carB"
                     /locus_tag="L1V17_001716"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBN1236484.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10933..12009)
                     /gene="carA"
                     /locus_tag="L1V17_001717"
     CDS             complement(10933..12009)
                     /gene="carA"
                     /locus_tag="L1V17_001717"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBN1236485.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12014..13294)
                     /locus_tag="L1V17_001718"
     CDS             complement(12014..13294)
                     /locus_tag="L1V17_001718"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBN1236486.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13313..14239)
                     /locus_tag="L1V17_001719"
     CDS             complement(13313..14239)
                     /locus_tag="L1V17_001719"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HBN1236487.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14252..15535)
                     /locus_tag="L1V17_001720"
     CDS             complement(14252..15535)
                     /locus_tag="L1V17_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBN1236488.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="L1V17_001721"
     CDS             complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="L1V17_001721"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBN1236489.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16323..17234)
                     /locus_tag="L1V17_001722"
     CDS             complement(16323..17234)
                     /locus_tag="L1V17_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBN1236490.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17231..17695)
                     /locus_tag="L1V17_001723"
     CDS             complement(17231..17695)
                     /locus_tag="L1V17_001723"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBN1236491.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17700..18398)
                     /locus_tag="L1V17_001724"
     CDS             complement(17700..18398)
                     /locus_tag="L1V17_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBN1236492.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18385..18771)
                     /locus_tag="L1V17_001725"
     CDS             complement(18385..18771)
                     /locus_tag="L1V17_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236493.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18918..20588)
                     /locus_tag="L1V17_001726"
     CDS             complement(18918..20588)
                     /locus_tag="L1V17_001726"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBN1236494.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20771..21004
                     /locus_tag="L1V17_001727"
     CDS             20771..21004
                     /locus_tag="L1V17_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HBN1236495.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(21103..21534)
                     /locus_tag="L1V17_001728"
     CDS             complement(21103..21534)
                     /locus_tag="L1V17_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HBN1236496.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            21613..22026
                     /locus_tag="L1V17_001729"
     CDS             21613..22026
                     /locus_tag="L1V17_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HBN1236497.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
BASE COUNT         6239 a         4926 c         3892 g         6994 t
ORIGIN      
        1 acctaaaaat ttggatttca acgatagaaa cactgttttt tatgtaatta gtccaagatt
       61 tttctagact tttgctttac tattcggcca aattggtttt tcttcttttt ttcgttataa
      121 tgaatatact tatgaaaaga aatgaggaat gaaccatgtc ctttgatggt gtatttaccc
      181 acgcgatggt caacgaattg cgtgaaacgt tactatctgg ccggatctcg aaaatccatc
      241 agccttatga aaatgaaatc gtgctggtga ttcgttcacg cggcaaaaac catcgattat
      301 tattatctgc gcacccaagt tatgctcgtg tacagattac ccaaatcgat tatcagaatc
      361 ctgataatcc gcctaacttc gtgatgatgc ttcgaaaata tttggatggc gctattttag
      421 aagacatcga acaaatcgaa aatgatcgag tgatccattt ccactttgct aaacgaaacg
      481 agttgggtga tctacaaaat atcatattga tcgttgaatt aatgggacgt catagtacga
      541 tcgtcttagt taatcgagaa actggaaaaa tactggatgc gatcaaacac attggaagct
      601 ctcaaaacac ttatcgttct ttgcttcctg gtgtagaata tgttgctccg ccaaaacaag
      661 aggtcttgaa cccatttagc tccgagaaag aaaaaatctt tcagcggctt tcccaaactg
      721 aactagatcc aaaagcaatc caacgtcagt ttcagggaat cggtttcgat atcgctcaag
      781 agctgaccaa aagattactg gaacgtccta atgaaaagat ggttgtatgg gacgaatttt
      841 tctcagccat cagccatcag cctattccta ctttttacga aacggaaaat aaagattttt
      901 tcacaccgat tgcttatcag gtattgtccg aacaggcatc tgctgtaaca gcttatccaa
      961 cactcagtca attattagat agctattatc acgaaaaagc agagaaagat cgggcaaaac
     1021 aacaaggcgg agaactgatt cgaaaaatcg aaaatgaact aaaacgaaat aaaaataaat
     1081 tgaaaaaacg tgaacaaaca ctcaaagaat ccgaaaacgc tgagaattac cgtagaaatg
     1141 gcgaactact tactactttt ctgacacaag taccacgcgg cgcaaaagaa gttgttttac
     1201 ctaattatta tgaagaagat cggccaatca aaatagcact agatccggca ttgacaccaa
     1261 atcaaaatgc acagaaatat ttccatcgat accaaaagct gaagaacgct gttaagctga
     1321 ttggcgaaca aatccaagaa gccaaagatg aaatccaata tcttgaatct gtcttatctc
     1381 aactggaaat tgccggccca atggatatcg aagcaattaa agaagaattg acttcagaag
     1441 gatacctgaa aaagaagaac ttaaaaaaac aaaaacgtaa gaaaccatct cagcctgatc
     1501 aatacttttc ttctgacgga acgctcattc ttgttggtaa aaacaatctt caaaatgacc
     1561 agctgacaat gaagacagct aaaaaaaccg actattggct tcatgcaaaa aatatacccg
     1621 gttcgcacgt catcattaaa agtgacaagc cctcagatga aacaattaca gaagctgccg
     1681 agttagctgc ctatttttca aaataccgat actctgccca agtgccggtt gatcttgtac
     1741 aggtaaagca tatccgaaaa ccaaatggcg ccaagcctgg ttatgttatt tatgaaaacc
     1801 aaaagacgat tatcgtgaca ccagaagaag aaaaaattac agctatgaaa caaaacaggt
     1861 aatcaatgag tgtttctaga atcatatttg cgtactttcc cacaacagca attagttata
     1921 aattgtttgc tacaaaaaga ggagttgtga caaaattctg tcacaacccc tcttttttga
     1981 tcaacggtgt tcaataaaca gcgttctcat ctgcttttct tagctctgct ggtccagtaa
     2041 ccgagtaagc tctttgataa atctttgagc gatttcactg agcggacgtt tcgccgaata
     2101 aatgatataa aattcattta gttcgccttc tgccaaaggg attaaccgca agtgctcgcg
     2161 aatccctcca atcacaatac cagatcctga agcgtaagca tcagtttcaa gaacgatatt
     2221 catcaaagta cctcgatcac tcgtataaat cactgtttct tgatcaggga tctcgataag
     2281 gtcttcataa aaatacggga aattatttcc atcctgtgta aaacgaactt gaggataaga
     2341 taacaattct tctttggtga tctctgcgtg ttcagctaat ggatgtcctt gccttaaaaa
     2401 aatatgcgtt ttgaattttc caatgctgcg gccacttagc tctccttgtt gtaaatatct
     2461 tctgatacca gcttgattat gctcattcat ataaataatg ccgatctcac tgtgctgctc
     2521 tttgacttct tcgatcactc tcgctgttgt cgtctccatg atccgaaatt gtttgatctc
     2581 gtctttgaat tcctcgagta gctgtgcggt caaaggacct aagaaatcat aatgctgggc
     2641 agcgatcgaa aaattgtctc tcttttcact cgttagatag tgagtttcta atgtatcaag
     2701 ctggaccaat attttctcgg cacgatttaa gaagtcttgc ccttcttctg ttaaatatgc
     2761 ccctcgattc gttcgagtaa acagcgtgat ccctaactcg gtttctaatt ctttgatacc
     2821 agctgaaaga cttggctggg agacaaacat tttctttgcc gcttctctga aactaccatt
     2881 gtttgctaca gcgaccacgt atttcatctg ctgaatattc attgctcaaa ctcctcgaaa
     2941 taataaattt ctcttccatt caagggctgg attggtcggt tgttcggtcg agcatactga
     3001 ccatcgaagg ggagaagaaa ctcttggttc agttttccta catgatccat tacaaaccat
     3061 tggattggcc cgctggtagg cggagttgtc aatgagccaa tataatggaa atggcttttt
     3121 tgctccggaa agaacacatc cggatttacc caatgctcat gtttttctaa gttccaactt
     3181 tccccatttt cttgattata cagccaacct tcctgtacca ttagctggta catgacaccc
     3241 acaactagat tctctttttt gctgttcata tgaacaaaat gaaattcaat atcttcctgt
     3301 tttccgttga tgatatgttc agaaggcaag tggaaatgaa tatctgtcaa ataatagcgt
     3361 tctttcttga actctacata actgagttgg tcaaaaggta ctaaatgaat cgtgtttttg
     3421 aattccttgt cagtaaaccg ttgcttttga taatgaaagg aaagcgtgtc tccttctatt
     3481 ttggtttctt cccccttggt caaatgaata ggcgactgca atggaaattc cgcacctctc
     3541 gcaaaccaat cacataaact cgcccaattt tccggacctt tgtctccaga atagccccat
     3601 tcgacatcca tattcttttt caactatact tccccctgca tctcatatca tttttatttt
     3661 tcttctttct ttacaatcgt tgagacggtt tctaaaaacg cctcttttcc ataaaattcc
     3721 tggttcaata gttccggaaa tatctcttta aagaaatact gaacagaagg ccgatgttca
     3781 aagcttttaa tcgtagtcac tgcctcaatg aacatctcct tataaacttt ttccgggtta
     3841 tttttgatga tttcatcaaa agattcataa agaaggtcaa ccttatctga aatggctaat
     3901 agttctcctt ctacggtttc atcttttcct tcgaacaacc gacggcgata aacttcttgg
     3961 aactcagctg gaatctcttg gttgatgaat tcgtccgtca tcttttcttc aactgtttgc
     4021 agcatccctc ttaactcttt gcttgcgtat ttcaccggcg ttttgatatc accaataaaa
     4081 cgctctgtgt agtcatgatt caatgatttt tcatagagca gtttccaatc gatcggttgt
     4141 ccattcgctt cttcaatgtc tcctagaact tgcgcaatag atgctacacg atacgaatgt
     4201 gctgcaactg tatgctctgt atatttaaaa aatccaggtg cccttgtgat cgtctctaaa
     4261 ttgttcaatc ctaaaataaa ttcattcaac cccataaaag ttacctccct ttgagatttc
     4321 tttttccgaa tatcatatca ttaaataact gatattcgca acatttccgc tctttaccat
     4381 ttttgaaaca gctcccttac caaaaaatag agaaaatcta tatataatag aaaaaagaga
     4441 agagattatt ctcttctttc tgctaaccag tcttagaaaa atgaatttta aaaaaatcaa
     4501 aaactgatca cgatagaagt ttcttttcat acctgatgaa aagatgcttc tcgcaatcag
     4561 tttttggatt tttgctattc caattgatga ttctggagac acaaatcgga tttctctatc
     4621 ttcatcaagc gcgcttaaat ctgccaattt tcaggatctt ttttccattc ttttagcaga
     4681 gttaattctt gctcatcgat ataacgatct tctaaagctg cttcaatcaa tacagaataa
     4741 ttggtcaacg tcataagagg gatttcggct ttttcgaaat ttgcttttcc ttttggcaac
     4801 tcatacgtaa agatagccgc aacaccaagg atatccgcac cttctctttt tgctgcttca
     4861 gctgcttcca agacacttcc gcctgtagaa atcaaatcct cgatcacaac catcttctga
     4921 ccttcaaata tacgtccttc gatttggtta cctttcccat gatctttcgc cttacttcga
     4981 atatagacca ttggcaaatc cagtatttcc gctacccatg cggcatgagg gattcctgct
     5041 gttgcagttc cagcaatcac ttgtacttca gggtaagctt ctttgatttt gcttgctaat
     5101 ccttttgcga tctcttttcg gacttttgga tagctcatcg tgattcggtt atcacagtaa
     5161 attgggcttt tgattccact tgcccatgta aaaggattac ttggatttaa aaatactgct
     5221 tcaatttcta ataagtcttt tgcgatactt tgttcaacat tcattttagg ttagctccat
     5281 tctgtttgaa tcgtttgata tgctttataa ggattagttg actgagtgat tggtcgacct
     5341 ataacgataa aagttgagcc gatctttttt gcctgagaag gtgtgactac tcttgtctga
     5401 tctcctgcga ctgttccttc tggtcttata cccggagtta agcaaacaaa ttcgtctcct
     5461 gccatttctt tgatcgcttc tacttcccaa gcagaagaaa ccacaccatc taatcctgct
     5521 tttttggcac agctagcata atggatcaca cttttttcta aagaaacttc gattagttga
     5581 tcggcatgca tttcttcttc acttgtagaa gtaagctgag tgatagctag aagtagcgga
     5641 cgttttccac cttctggagt cccctcttct aatcctcgca ttgccgcctc catcatacga
     5701 ataccgccag cggcatgaac acaggtgaga tcaacaccaa gctttgccaa tccccgcatt
     5761 gctttttcga ccgtattcgg aatatcgtga agtttcagat ctaaaaatac attatgacca
     5821 gcctctttta gataacgtac gatttcaggt ccttcttggt agaacaattc cattccgatt
     5881 ttcacaaaca atttttcttc tttcgggaaa aatcgaagaa agtcttctac ctcttgccta
     5941 gttgaaaaat ctaatgcaat aattggtcgt tggtctagtt gattcatcgt tcacgttcct
     6001 ctctcacttc tttgattaat ctttccagcg attcgatgcc tagttcgctc attcgcacag
     6061 ggagctcttt aattagttta ggacagatat acggatcggt gaaattcgcg gtccctatag
     6121 ctacagcact tgctccagcc ataaacatct caagaacatc atccactgtc tgcacgccgc
     6181 ccatcccaat gattggaagg ctggatatac ttgctacttg gtgaatcaaa cgaatagcga
     6241 caggcttgat tgctggtccg gagagtccac ctgtttgatt ggctaaaatc ggttttcttg
     6301 tcttaaggtc aatccgcata ccaagaagag tattgatcat cgtaaaccca tctgcccctc
     6361 cagcttcgat tgcctgagcg attggaacga tgtctgttac atttggggac aatttgacat
     6421 agacaggaac agaagaaact ttctttactg cttgtgttaa ttgaaaagca acatcagaat
     6481 ctgttccaaa agcaattccg ccatgtttga catttgggca agaaatgttc agctcgattg
     6541 ctttcacatt tggtgcttcg ccaattttgc tacaaacttc tacatagtct tcttcacaag
     6601 caccagcaac atttgcgatg atgggtaact cattgtactc ctctaattct ggaagaagtt
     6661 tatgcataac aacgtctaga ccaggatttt gcaaaccaat tgcattcaac atgccagatg
     6721 gtgtttccgc cactcttggc gtgggattgc caaagcgggc atttggagtc gttgccttga
     6781 ccatgatcga tccaagctga ttcaaatcat agtattttcc gtattctttg ccaaaaccga
     6841 aacagccgct tgccggcatg ataggatttt ttaattctag gccaggaagt ttgaccgcta
     6901 aaggattctc attcatataa ttacctctcc tattttaaaa atcggtcctt cgtcacaaac
     6961 tttcacactt tttgttcctg tttcatcttc cggcgtatga caaacgcaag catagcaagc
     7021 ccctatccca catgccatgc gggattctaa tgataactgg acattttgat gcgaagaaaa
     7081 cagctgttcc actgtcttca ataacccgtt tgaaccacat gcaaaaacag ctgtaggttc
     7141 cgtcttcgtt cctaacaata aattaccgac atttccgtgc ataccgtatg ttccatcgtc
     7201 agtagcgatt cttgtttctc ctagacgatt aaattctttt tcataataaa cgacttcatg
     7261 tgtggcaaaa cctaaaaaat gcgttggctt aattcctttt tcgactaact gttttgataa
     7321 ctcatataga ggagggacac cgattcctcc accgattata aatacttcgt ctcctgtatg
     7381 aagattggac aaatcaaaac cattgcctaa aggacccatg acatctaaat ggtctccggc
     7441 agaaagagta gagaagactc tagtcccctc accttccacc cgataaatga tacggcaagt
     7501 atttgtttcg tggtcgatat gattcaagct aatcggtcgg cgtaatagca agtctgcacg
     7561 cggcacgaga atatgcaaga actgtcctgg ttgctgcatt tcttttacta gatcaccttt
     7621 caatgtcatt tcaaaaatct ttggtgccag ctgtttttgc tgaacgattt ccatcatttc
     7681 ttgtttcatc tgtcccctcc tgcaacggtt tttcgtcttt ttgtcttaac atgtgctcgc
     7741 cgttaaatag ggttagttga aaaagcacgg gattccatca ctcgaacgat cgcatctgct
     7801 gtgtctaaag aagtaaacaa tggaatacca tgttcaactg cttctcttcg gatgatgaaa
     7861 ccgtctttag aagcatttcc ccgatcttta tcaatcgtat tgacaaccac ttgtgtttta
     7921 ccatctctta ttaagtcgac tacatttttt tctgctgctt cctcagaaat tttcgctact
     7981 gtttcaacga ccagaccatt tttttcgaaa taagcagctg tatgtttcgt tcctatcaga
     8041 ctatagccaa tttctgtaaa acgtttagct aattctagtg cttcttcttt tgtttcgtcc
     8101 gcaatcgtaa ataatacggc tccatattca ggcaagtgta atccagaagc ttcgaatgcc
     8161 ttgtacaaag ctttgtctaa ttgtctgtca gatcccatta cttctccagt cgatttcatt
     8221 tcaggcccta agtaagtatc aactttctgc aatttcgtaa aagaaaagac aggtgcttta
     8281 acatgaactt cttttgtttc tggataaagt ccgttttcat aaccaagtgt ctttagtttc
     8341 tctcccaaaa tagctttcgt cgcaatttgt gccattggaa ttcctgtcac cttacttaag
     8401 aatggaacag tccgacttgc tcgaggattg acttcgatca cataaacctc attttcatgg
     8461 atgacaaact ggatattcat catcccgaca caattcaaac ctaatgctaa gcggatcgtg
     8521 taatcttcga tcgttttctt gatcgattca gataatgttt gaggtggata cacagccatt
     8581 gaatcccctg aatggacacc agcacgctca atatgctcca tgatccctgg gatgagtact
     8641 gtttcaccgt cacaaatcgc atccacttcg cattcaccac caagcaagta acggtccact
     8701 agtactggat gttctggaga tgctttcaca gcatgttcca tgtaatcttc taaatctcgc
     8761 tggttttcaa cgatttccat cgcacgtccg cctaatacat agcttggacg aacaagaact
     8821 ggataaccaa ttctcgaagc gataaccacg gcttcttctt tacttgtagc agtatcccct
     8881 aaaggttgag gaatatccaa ctctttcagc gcttgctcga ataaatcacg attttccgca
     8941 cgatccaagt cttcgatcgt tgtccctaag atttttacac cagcagcagt caaaggttcg
     9001 gctaagttga ttgctgtctg accaccaaat tgaacgatta ctcctatcgg ctgttctagc
     9061 tcgatcacat tcatcacatc ttcgaaggtc aatggctcaa aatataattt atccgaaata
     9121 gaaaagtcag tcgaaactgt ttcaggattg ctgttcatga tgattgcttc gtatcctgcc
     9181 tgctggattg ctttgacaga atgcacagtc gcatagtcaa attcaacccc ttgtccgata
     9241 cggataggac cagatcccag tactagaatt gagggctttt ctgatcgtga actttcattt
     9301 tcatattcat aggaactata aaaataaggt gtttttgatt cgaattccgc tgcacaagtg
     9361 tcaaccatct tatatacagg aatcaaatca ttttcttttc tcatctggcg aacggcttct
     9421 tcgtttattt cccacagctc cgccactttt ttgtctgtaa aaccgttttg tttcgctgtt
     9481 ttcaatatct tgtcatccaa cggctgctgt ttcaactgct gttcgatttc tacgatatgc
     9541 aacagtttat ctaaaaagaa taaatcgatt tttgtcaaat ccgctaattc ttctatggtg
     9601 taccctcttc taatagcttc agctacataa aacaggcgat catcttgtgc tcgaaccact
     9661 ttttggatta ggtcatcgtc cgtgatgtct gccaactcag gaagttcgat atggtgtgta
     9721 ccgatttcta aagaacgcac agctttcaat aaagactctt cgatattccg accgatagcc
     9781 atcacttcac cagttgcttt catctgcgtg cctaaaagcc gttctccgtt ttcaaactta
     9841 tcaaacggcc agcgaggaat tttagctaca acataatcta atgcaggttc aaattctgca
     9901 aaagtcgttc ctgtaacagg atttttcatt tcgtctaatg ttaatccaag cgctatttta
     9961 gcagctagct tagcgatcgg atagccagtc gccttacttg ctaacgcaga tgaacgagaa
    10021 acacgcggat tgacttcaat cacataataa ttaaaactat gtggatcaag agcgagttgg
    10081 acattacagc ctccctcgat cttaagtgct cgaataatcg aaagagaagc atcacgaagc
    10141 atttgatatt catggtcaga caatgtttga ctaggggcaa atacgataga atcacctgta
    10201 tggataccca ccgggtcaaa attttccata ttgcagacaa cgattgcatt atcagccgaa
    10261 tctctcatca cttcatattc aatttcttta aaacctgcaa tacttcgttc aatcaaacat
    10321 tgggtagcgg gggaaagact taatccattt tctgatacga tacgtaattc ttcttcattt
    10381 tcacacatac ctccaccagt tccgcctaaa gtaaaggctg gacgaacgat gacaggatag
    10441 ccgattttat ttgcaaaatc tacagcttct tctactgtat tgacgatttc agactcgggg
    10501 attggctgat tcaattcttt catcaactgt ttgaatagat cacgatcttc tgcttgatcg
    10561 atcgcagaaa gctttgttcc tagaagttct atgttcaatt cttctaaaat acctgatgct
    10621 gccagctcca ttgccatatt gaggcctgtc tgtccgccta aagttggaag gagagcatct
    10681 ggacgctctt ttcgaagaat ccttgataca aattcaagtg tgatcggttc gatatatact
    10741 tgatctgcca cttctttatc cgtcatgatc gtcgcaggat tagaatttac taaaaccact
    10801 tcatatcctt cttcttttaa ggcaaggcag gcttgtgttc ctgcgtagtc aaattctgcg
    10861 gcttgaccaa tgatgatcgg accagatcca atcaccataa ttttcttgat atctgtacgt
    10921 ttcggcatct gtttactgct cctttcctgc gtccatcatt tccataaatt catcaaataa
    10981 atgtagtgca tcatgcggac caggggcagc atctggatga aactgcacac tgaaagcggg
    11041 ataatctctg tgtttgactc cttctactgt tccgtcattt acttctacat gagttacgat
    11101 gagtttttct ggatcaatcg tggcttcatc gactgcatag ccatgatttt gagaagtaaa
    11161 atcaattctt ccggtcgcta cttctcgtac cgggtgattt aatcctcgat gtccgaattt
    11221 cattttatag gtatctgcac cgttggctaa agcaaataac tggtgaccga gacaaatacc
    11281 aaaaatcggt acttttcctt ggattttttt gatcatttcg attgcttctg gcacatcttt
    11341 tggatcacca ggtccattcg tcagcatgac tccgtctggt gatagcgcta aaatcgtctc
    11401 ggcatctgtg ttatagggaa gtactgtgag gttacagttt cttttactca attctcgtaa
    11461 aatactatgt ttcaagccga agtcaatgac aatgactttc cgacctgttc ctggacttgg
    11521 ataaggtttg ttagttgaga cttgctgcac ttgattggtt gctagaacgg ttgctttcag
    11581 ctgatcaaat gcatgttcga aggaatctcc agcatcaact atactagctt tcatcgttcc
    11641 gacttcacgg attttgcgag taagggcgcg cgtatcgata cctgatattc caggaattcc
    11701 tttttgtttc aaaaatgaat ctagcgtcat ttggtttcgc cagtttgaag ctacacgtgc
    11761 atgttctttt actactactc ctttgcatgt tggagaaatc gattcataat catctctatt
    11821 taccccataa ttacccacca taggataggt aaatgtaatg atttgaccgt taaaactttg
    11881 atcagtgata gtttcttgat aaccagtcat acttgttgta aaaacgattt ctccgaagac
    11941 actagcatct gcaccaaaag cctttccttc gaaaactgtt ccatcttcta atataagcaa
    12001 acgttccata cttttattct cccttctgcc acacaagttt tccgttgaca aaagtcattt
    12061 gtgtttcgcc ttttactttc cagccgataa aaggtgtatt ctcccctttt gataaaaagt
    12121 cttctttatc gatcgtgcaa gtttgtgtaa tatcaaaaac tgctacatca gcgggggcac
    12181 caaccgttag cgttcctgca ttcaaaccaa aaatctcagc cggtttaact gccaaccaat
    12241 tgatcacttg ttccaacgtg aatcgaccag tttctacaaa atgagtatag atcagttgaa
    12301 acgctgtttc gcttcctacg ataccaaatg gtgatttcat gaaactttgg cttttttctt
    12361 ctaatccatg gggggcatgg tctgtagcga tgcaatcgat cgtaccgtca agcaagcctt
    12421 cgatcaaagc ttctctgtcc tcccgtcctc ttagcggcgg gttcattttc caaaagccga
    12481 aatcttcggg aatatcttcg tcgatcaaaa taagatgatg gggtgaaact tctgctgtta
    12541 cgtggattcc tgcttttttt gcgtctctga ttacacggac actttcttta gtagaaacat
    12601 ggcaaacatg gtaatgaaca ccagttgctt cagctagcaa cagatctcta gcaatttgag
    12661 aagactcggt tacgcttaag atcccgggaa gaccaagttc ttctgccttc ttgccagcgt
    12721 gcataacgcc gccaaataat aaagattcat cttctgtatg ggctactagg gctttattgt
    12781 tttttgcagc ttctttcata gccagataca tcgtcccagc tgtttggaca cctacaccgt
    12841 catttgtgaa agcaaaagca ccttcttcaa tcagtgcttc ttgatcaact aatttctcac
    12901 ttcgcagatt ttctgtgatt ggcgcatact gcaatacctt cacaactgca tcttttctaa
    12961 tgatgtcata tacttgtctc agcttttctg ccgtatcagg tacaggattt aaattcggca
    13021 tcgcgcatac agtagtgaaa ccgccacgag cagctgagcg agtcccagct tcgatcgtct
    13081 ccttgtatgt aaatcctggc tctctcaaat gaacatggac gtccactaaa ccaggtgtga
    13141 tcaattgtcc ctttgcatca aacacttcat caaattcggc ttctgagaat cctgtaccga
    13201 ttgctttgat tcgcccatct tctatccaaa tttctgctgg tgtcgtcata ttttttcgtg
    13261 tattgatctg accgttttta atgagtgttt tcattttttc atcctcctat aattacgctt
    13321 ttccatttag cactgcttct aagattgcca ttctgacgaa tactccattg ctcatttgct
    13381 gaacgatccg cgactgtaat ccttccacta atgaatcagc taattctaca tcacggttaa
    13441 ctggtgctgg gtgcataatg attgcatgtt tttgcaactt cttcgcacgc tcaactgtta
    13501 acccatgttc ctgatggtag ccttcttttg agaaactttc ttttccatca tggcgttcgt
    13561 gttgcacccg aagcatcatc atgacatcaa cttgatctag tagttcatcc aatggcatat
    13621 aatgtccgta cacttcgaat tcatcgtcgt accattctct aggacctgag aagaatactt
    13681 gtgcgcctag acgttttaac atctgcatat tggatttagc tacgcgagag tgagtgatat
    13741 cacctacgat ggcaactttc agaccttcaa aatgaccaaa ttcttcataa atggtcatca
    13801 aatcaagcaa gcattgggtt ggatgctgtc cgcttccgtc tcctccattg ataatcgaac
    13861 actggattgt tttactttgt atcagttcgt cataatagtt ctcatcacca tgacggataa
    13921 ccgctacgtc tacgcctaat gctgacatcg tcagtactgt atcgtatagt gtttcccctt
    13981 tttggacaga gcttgtgctt gcttcaaatt caatcacttc tagccctagt tttttctccg
    14041 ctacatcgaa gcttttatgt gtgcgagtac tattttcgaa aaagaggttt gtagcaaagt
    14101 actggcgctt ttgcggagtc caattagcac cttgcttgaa ttcctgccct ctgcggatca
    14161 agcccataac ttcttgatca gtaagtgcct caacggtcaa taaatgcttt aagctgatac
    14221 gttctgattt gatgatcata atgtttcctc cttagttttc ttcgcttcgt gaagtttctg
    14281 gtaagataag atttaaaatg atgccaagta cagttgctaa tgccattgcc gacaatgtaa
    14341 atgtgcctac ttcaaagacg agtccgccaa ttcctactac taagataact gaagcaatca
    14401 acagattttt ctttttatca aaatcgattt tgttctcgat taaaatcttc attccacttg
    14461 cggcaattac tccaaataag ataaaactga ttcctgagat gactggtcca gggatactta
    14521 aaatcaaagc gcttaatttt cctacgaatc ctaaaatgac tgcaaatact gcagctccac
    14581 cgatcacaaa cacgctatgg acacgtgtga tagccagaac accaatgttt tcaccgtaac
    14641 ttgttacagg aggacctccg acaaaggctg ccacgatttg tgctaatcca tcacctgtca
    14701 acgtcttatg aagacccggt tcttcaaaga aattacgttt agttagttta ttcaatacca
    14761 taagatggcc gatatgctct gtcatcgtca caaaagcgat gggtgccatt gttgtgattg
    14821 ctccaagata tagctttggt tcatattgta caaagggaat ctcaaagtta ggaacagcaa
    14881 accaggcagc gtctacgatt ggcttagtat ccacgattcc aaacagcaag gctacgatgt
    14941 atccgctaat aatacctagt aaaatcggaa tcaatccgag aaaacctctt agccacatgt
    15001 tgaagaaaat tgttaatcct aatgtgatca gcgctacagc aatatacttg aaatcatacg
    15061 tgccctgatt atacatagca tttgttgctg catttgccgc aagtcccaac ccgataacca
    15121 tgatgactgg accgacgacg attggaggca agattttatc cagccatgct gaaccgatct
    15181 ttttgatgat cagcgcaaca atcaaataga ctaatccagt tgtgactgct ccttgtgcaa
    15241 tcgctggata accatctgtt ttcatcaaaa gctgcatcgc tgcaatgaaa gcgaagctgc
    15301 ttcctaagta cgcaggtatc tttcctttag tagtaaataa gtacaccaat gtacctagtc
    15361 ctgaactgac tagcgcaata cctggatcga tacctactaa gatggggact aacacggttg
    15421 ctccgaacat cgtgaacaag tgttgtaaac ttaatcctac ccaatgtcct ggggttgggc
    15481 gatcgtggat atctaacacc acgtcatcat tatgaaatcc ttttttctcc gacatgtttc
    15541 tctctcctct aatcttcctc tttcaaaatc atgatgcgat cttgtccatc aagctcttgc
    15601 atctctacta aaatctcttc cgcccgagat gttggaatgt tcttcccaac ataatctgca
    15661 cggattggca attctcgatg cccacgatcg accaggactg ctaatgaaat ttttcttggt
    15721 ctgccaaaat ccattactgc gtccattgct gctcgaatcg ttcgtcctgt atacaaaaca
    15781 tcatcaatca aaataacttc ttttccttct aaggaaactg ggatgtcaga agaatgaagt
    15841 tccggttctt ctggattttc ttttttgtca tctcggtata aagtgatatc cagttctcct
    15901 acaggaatat cgatatcttc tagctgcttc aggcgttcgg caattcttga tgcaatgtag
    15961 attcctcgtg ttttgatacc taccaatacg atatcttgga tactatggtt tctctcgata
    16021 atctcataag taattcgagt caatgctcgc ttcatggtta cctgatctac tacttctttt
    16081 gcttgcattt tcattccccc tacttttttg cataaaaaaa ctcctgccct aagaggacag
    16141 gaggaatgtt tagactgagc gtatactgat acactgatag ctatactatg tcaatgagca
    16201 atctacttat ggcgcaccat acgtatcctt gctcccaccc ttcttagcct cacgggacta
    16261 aacttaaagg aattctatta agttttatgc tttcgttgtt aattactata ccgttatcta
    16321 aattaaaatg caatgttttt tcttaatttt tctaaagttt tttcaaaaac ttctggaaga
    16381 ggtgcttcaa agatcatctt ttcgtttgta gtcgggtgcg taaaacctaa catttgcgca
    16441 tggagaaact gaccattgcc tttcaaagtt ttcttcggtc cgtatactgg atctccagct
    16501 aacggataac cgatatactt catatgcaca cggatctggt gtgttcttcc ggtttctagt
    16561 tttaattcaa ccagagtaaa tccttcgaaa cgttccaata cagtaaaatg tgtgacagcc
    16621 gacttcccat cttctcttat cgcctgcatt ttccggtttt ccttcgaacg gccgattggc
    16681 gcattgatgg ttcctttttc gtgaggaatc tctccatgga ctaaagcaac atatttgcgc
    16741 aaagaggtct tatcttttaa ttgctgagct aatgattcgt gtgcctggtc atttttggca
    16801 accattagca gtccggaagt atctttgtcg attcggtgaa caatacctgg acgaataacg
    16861 ccgttgatcg tagaaagatc cttgatatgg tacatcagcg cattgaccat tgtgccatgc
    16921 gtatgacctg ctgaaggatg aacgaccatt ccttgaggtt tgtttatcac cgctacatct
    16981 tcatcttcgt aaacgatcgt caacgggata ttttctggga ccacatctaa tgtttctggt
    17041 tcggggatca agacagtaat ctcgtctcct tgttttactt tgtaatttgc tttgactggc
    17101 tgtccattga cagaaaccgc tccatttttc agccacagct gaatttgcga acgactgtaa
    17161 tcggtgaata aattagtcaa tactttatcg atcctaccag attcatggtg aatcgtcgtt
    17221 ttaagttctg tcattttttt ctttgatcct tttcatctaa aataatataa attaacatac
    17281 aaatcactcc acatacaagt gtcacatctg ctacgttaaa aatcggaaag ctcataaaat
    17341 ctgtctggaa catatctact acatagccaa gacgaatacg gtcgataaaa ttgccaatcg
    17401 caccagctag aatcaaactc aatccaatca tgaaccagcg attacctttt tcacgatttt
    17461 taatcatcaa tgtgagaatc acaacgactg caatgagtgt cactatagta aagaaccaca
    17521 tcttcccttc tagcatactc catgcggctc cagtgtttcg aatatgattc agtgacaaaa
    17581 tacctggtat aagatttttc gtctctccaa gcgctagatt atcagtgatc caccatttga
    17641 ccaactgatc cactcctact agcaaagcgc tgaatatcca ataaataatt aacaaaaaat
    17701 caatcctttt ctatttgttt ataaatatca cgaggtcgta cgatcccgag cagattacca
    17761 tcgggattcc catctttagt gataagtacg gcttccaaag tcccttgctc acgaaacatc
    17821 gcttcaacct cgtaaatatg tgttttagct ggaacaaaat gataatttgt gtactttccg
    17881 ttttggatga tcaaatccaa cgctcgttta tttgttaaat caaccggacc tttttggctt
    17941 tcttttgcta gccaaaaccc gatattacgt aaagtaatca atgctacaaa ttttccttta
    18001 ttgtataacg gaaattgtga ataccttttt tctgctacta tctttaacag ttcaagtaac
    18061 ggaagatctt gttcaaaacc tgttacacgt tttgcaaatc gaggcagcac ggtttcaggc
    18121 tgaatcagtt cttgttcgat cagctggatt cgcttgactg tccaatcatt tggctctgca
    18181 atgacaaaat cgactgcgat ccgatcatgg acgatcgcat tccttaactg agcaagctgt
    18241 aaaagatcat cttcgtattt tctgatcatt aattgttttc tttgagctag gcgtctgaca
    18301 agttcggtaa atcccatatt tcgtgcattt cccatctcgt ctctcatcca tttttcgatt
    18361 cgattgaaac tgattaaaaa aagatcagag tttgccataa ttttcctcct tgatcaaata
    18421 tgcccggttt tttatataga aaaagaacgc aatcaacaca ataactgcaa aaaaactgaa
    18481 aaataaattt tgtaggaaaa cggcccccaa cccagttgct agaaataaaa acggatagat
    18541 ttgaagaatc aagtaattca ttgtgatcac ataagcaggc tttgcttctt tcactgtata
    18601 aacggggctt tttagccaat aaaaggtgac ctgcatcgta aagggcactt ccagatcaag
    18661 cgttatcttt tgttcatgac tgagaacact gcgtttttca ttgttgattc ttagctgaat
    18721 cgagctaccc ataccgtaaa aaccggtttt tcttataaat gtcgttttca tcataccctc
    18781 ctattatgct ttagtatagc tcaaaataca ataaagaaaa agaatgatcc tagtgtaaac
    18841 aaaattaatt ccctatcgtc taaaaaaaga agctgtagtc aaaatacagc tccttcgatg
    18901 gtagattata atcaagctta aaacaatccc aacacttctc cgtcatttgt cacgtccata
    18961 ttcaatgcag caggtttttt aggcaaacca ggcatcgtca taacatctcc agtcaaggct
    19021 actaaaaatc ctgcccctaa ttttgggatg atttcgcgga tcgtgatggt gaaatcttcc
    19081 ggtgcaccta gcagtgaagg atcatcagaa aatgaatact gtgtttttgc catacaaatc
    19141 ggcagtttgt cccatccatt cttcgtaaac tcttctattt gtttttgcgc ttttttgctg
    19201 aaaacaacac catttcctcc gtaaattttc ttgacgattg tttctgtctt ttcttgtatc
    19261 gtttcttcta ggcggtataa tggcttgtaa ttagcttctt ttctatcaat caatcgtact
    19321 acagcttttg ctaaatcaac gccgccttct gctccatctg cccatacact cgctctcttg
    19381 gcaagaatcc cctgattttc acacaagtgc tccaacagtg tgagttcatt gtctgtatct
    19441 gttacgaatt cattgattgc gacgatcaca ggtagctgat attgttccat attacgtata
    19501 tggcgcttta aatttgcaaa acctactttc aaagcatcaa gattctcatt tttaagttca
    19561 tcttttttca ttccgccatg cattttcaat gcacggacag tggcgacaat caccacagca
    19621 tccggcgctt ttttcaagtt aggtactttg atatctaaaa atttctctcc gccaagatct
    19681 gcaccaaatc ctgcctctgt gacaacgtaa tctgctaatc tcaatgctgt cttggtagct
    19741 aaaatactat tgcagccatg agcgatattg gcaaacggtc ccccgtggac aaaagctggt
    19801 gttccgtaaa ttgtttgtac aagattcggc ttgattgcat ctttcagcag taatgccaga
    19861 gcgccttctg ctttcaagtc tccagcagtc acaggctgac ggtcaaatgt atagccgaca
    19921 acgatccttg caagacgagc ctttaaatct tcaaggtctg ccgcaagaca caagatagcc
    19981 atgatttcgc tggcaactgt gatatcaaac ccatcttctc ttggaacacc ttggattggc
    20041 ccacccaagc caacaattac tttacgcagt tcacgatcat tgagatcgac tacccgtttc
    20101 caaatcactc ggcgggcatc gatgttcaat tcatttcctt gatgaatatg attatctaaa
    20161 agagcagata atgcattatt agctgttgtg atagcatgca tgtcaccagt aaaatgcaag
    20221 ttgatatctt ccataggcaa tacctgtgca tatcctccgc ctgcagcacc acctttgatt
    20281 cccatcacag gaccaagtga gggttctcgc aatgcaataa cagatttttt attgatttta
    20341 ttgagcgcgt ctcctaaccc tacagtgatc gttgactttc cttcgccagc tggtgttgga
    20401 ttgatggaag taactaagat caaatgcccc tcagcgttat cctttgatcg attgattcca
    20461 gaaaaattga ttttcgcctt atatttccca tacagttcca aatcgtcttc cttaagatct
    20521 aatttactag ccacttcaac aatcggttct agctctgttt cttgtgaaat ttgcagatca
    20581 ttcttcattt gattacccct tttcacgaac tttattcaac aaaatatctt ctttgttaag
    20641 atatgccaat tatacctttt tttattcaga aaaaaaacat aaaattacag gtttttaatt
    20701 tatttgacgt acttataaat actctttata atgaaggcta tgatcagact ttagaaaggt
    20761 cgtgagtgct ttgaccacag gaattgtaaa atggtttgac aacaaaaaag gatacggctt
    20821 tatcagttat gatgacacag aagaaatttt tgtacatttt actgcgattg aagaagaggg
    20881 attcaaaact ttggaagaaa atcaagtggt cgaatttgag atcatcgaag ggaatcgagg
    20941 aacacaagct gcccatgtca agaaaggcaa cgttcagact accgatacta gtatgcatga
    21001 atagataaac aaatagagtg agacgctaaa cgggatgaac cgtacgtctc actcttttct
    21061 tttcctgtaa aaattcgttt ttttaggttc tgatttttaa aattagcttt ttcttttttt
    21121 cgtataagga taaggaattg attctgattt gggtccgttt ttttcaaaat gatcaaaaag
    21181 gactacttga tctttttttc gcatcatgaa aacagatggg gctttctcat cttgcaacat
    21241 catttgcacc ccagtattag ttggcgtcaa agatcgaatc tgtccgacag atatttctcg
    21301 gtctttccaa aaagcagcat aacgtataat cacagagttt gattttaaaa taaaagaacg
    21361 ccgcaaacct agaaatagaa aaacaagaaa aatacctaaa acaaaattgc ttttccaata
    21421 aggacctgtg ttttctaaag aaagaatcag actaaaaaac agaatgatca aggtcaatga
    21481 ccaatagatg atcgtatgtg ccagttcagg ctgccatcga atattttttt tcattctcta
    21541 acctctcacc gattcagtaa tgatataatc ttaccataac attagtttga acaaaaagga
    21601 gaatctcttt ttatgttaaa agtatacatt gatgcctcta caaaaggcaa ccctggtcct
    21661 agtggaggtg gaatcttgat tgtctatcaa ggtaaacaag aacagctatc tatcccgctt
    21721 tctataggga caaaccatca agcagagttc gaagtctttt taaaaacttt agaatttcta
    21781 aagaaaaacg acttacagaa tgaaacgatt ttctgttttt cagacagcaa aacactagtt
    21841 tctacggtcg acaaaaacgc aacgaagaac gagctcttcc ttccctacct tcaaagaatc
    21901 caagaacttc tatccgaatt ttctttattg atcctgcaat ggttgcccga aaacaaaaat
    21961 aaaggagcag ataatcttgc acgtcaggct ctccataaac aattaaaaga aaaaaagact
    22021 ctttaaatta aaaactttaa ggagtctttt t
//
LOCUS       DAFLWC010000051        21553 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.052, whole genome shotgun sequence.
ACCESSION   DAFLWC010000051 DAFLWC010000000
VERSION     DAFLWC010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21553
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.052"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(270..1766)
                     /gene="lysS"
                     /locus_tag="L1V17_001730"
     CDS             complement(270..1766)
                     /gene="lysS"
                     /locus_tag="L1V17_001730"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBN1236498.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1877..2881)
                     /gene="dusB"
                     /locus_tag="L1V17_001731"
     CDS             complement(1877..2881)
                     /gene="dusB"
                     /locus_tag="L1V17_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBN1236499.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2882..3769)
                     /gene="hslO"
                     /locus_tag="L1V17_001732"
     CDS             complement(2882..3769)
                     /gene="hslO"
                     /locus_tag="L1V17_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBN1236500.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3986..6097)
                     /gene="ftsH"
                     /locus_tag="L1V17_001733"
     CDS             complement(3986..6097)
                     /gene="ftsH"
                     /locus_tag="L1V17_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBN1236501.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6187..6732)
                     /gene="hpt"
                     /locus_tag="L1V17_001734"
     CDS             complement(6187..6732)
                     /gene="hpt"
                     /locus_tag="L1V17_001734"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBN1236502.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6732..8177)
                     /gene="tilS"
                     /locus_tag="L1V17_001735"
     CDS             complement(6732..8177)
                     /gene="tilS"
                     /locus_tag="L1V17_001735"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBN1236503.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8297..8767)
                     /locus_tag="L1V17_001736"
     CDS             complement(8297..8767)
                     /locus_tag="L1V17_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HBN1236504.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8813..9238)
                     /locus_tag="L1V17_001737"
     CDS             complement(8813..9238)
                     /locus_tag="L1V17_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBN1236505.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9305..9574)
                     /locus_tag="L1V17_001738"
     CDS             complement(9305..9574)
                     /locus_tag="L1V17_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBN1236506.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9585..11180)
                     /locus_tag="L1V17_001739"
     CDS             complement(9585..11180)
                     /locus_tag="L1V17_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBN1236507.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11195..14716)
                     /gene="mfd"
                     /locus_tag="L1V17_001740"
     CDS             complement(11195..14716)
                     /gene="mfd"
                     /locus_tag="L1V17_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBN1236508.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14733..15293)
                     /locus_tag="L1V17_001741"
     CDS             complement(14733..15293)
                     /locus_tag="L1V17_001741"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBN1236509.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15646..16620
                     /locus_tag="L1V17_001742"
     CDS             15646..16620
                     /locus_tag="L1V17_001742"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBN1236510.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16790..18190
                     /locus_tag="L1V17_001743"
     CDS             16790..18190
                     /locus_tag="L1V17_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBN1236511.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18268..18990)
                     /locus_tag="L1V17_001744"
     CDS             complement(18268..18990)
                     /locus_tag="L1V17_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1236512.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19069..19575)
                     /locus_tag="L1V17_001745"
     CDS             complement(19069..19575)
                     /locus_tag="L1V17_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBN1236513.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19698..21497
                     /locus_tag="L1V17_001746"
     CDS             19698..21497
                     /locus_tag="L1V17_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBN1236514.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
BASE COUNT         5988 a         4708 c         3871 g         6986 t
ORIGIN      
        1 ttttgttatg tttttgaata aatattttct tctgtctttt ggacaagtaa taatatacca
       61 actaaattta gcttggtcaa cgaatttttt gtattttttc aagttttttt caataaacga
      121 ttattcataa cttttctttc tttatcgttc gttttcgtct tctttaatgt ctagaatagt
      181 cggcattagc ttttgaactt tcgttattat ttattccttt ctacacagca aaagctgcct
      241 aaggaattcc ttagacagct tttattcgat tatctcattg ttgggaatag caaaacatcc
      301 cgaattgatt gtgcatcagt tagcaacatt actaatctgt cgatcccgat gcctagacca
      361 ccagttggcg gcataccgta ttctaaggct tccaagaagt cttcgtctac accgtgagct
      421 tcgtcatttc ctagttcacg ttctttttct tgcgcttcga atctttctct ttgatcaatt
      481 ggatcgttca gttctgtaaa ggcattagca aattcgcgcc ccactatgaa tagttcgaat
      541 cgatctgtga atcgaggatc ttctggattt ttcttcgcta aaggcgaaac ttcgactgga
      601 tgtccgtata caaacgtcgg ttgtgtcaat gtttcttcaa caaatgtttc aaagaattca
      661 ttgataacat gtccgacacc catagcttcg gttacttcta cattgtgttt ttcggctaaa
      721 gctaatgctt cttccaatgt catttcttgc cagaagtcta caccagtttg ttctttgatt
      781 gcatctacca tatggatgcg tttaaagtca ctttctaagt cgacagcttg tccatcatat
      841 gtgatttttg ctgttcctag tactttttca gctgcgttac ggataatacc ttctgtcaga
      901 ttcattacat cattgaaatc agtatatgct gtgtatgctt ctaacatcgt aaattctgga
      961 ttatgtgtag tatcaattcc ttcattacgg aaaacgcggc cgatttcata aactttttcc
     1021 attccgccaa caattagtcg ttttaaatga agttctagcg caatacgcaa atataaatca
     1081 atgtccagtg cattatgatg cgtgataaat gggcgtgcgg cagctccacc tgcctcattg
     1141 tgcaatactg gtgtttctac ttcaatatag ccattgccat ctaaatagcg acggatttcg
     1201 ctgataattt ggcttcgttt cataaatcgg tcaaagcttt cgcgattact gattaaatcc
     1261 aagtagcgtt gtctgtagcg ttgttcaata ttcgttaagc catggtattt atctggcagt
     1321 ggacgaagtg cttttgacaa aatcgtgatt tctgaagctt tgatagaaac ttcgcctgtg
     1381 tctgttttca tgatttgtcc agttacacca aagaaatctc caaggtctgc atgtttgaat
     1441 acttcatagg cctcatcacc tacttggtct tttcttacat aaatttgaat ttggccttca
     1501 cgatcttgta gatgcgcaaa tccagctttc ccttttcctc ggcgagtcat catacgacca
     1561 gctacactag cggtcaatcc catttctgct agttcttctt ttgttcttgg atcaaatagt
     1621 tcatgcaatt cttctgagtt gtgcgtgcgt tcaaatcgtt ttccaaatgg atcgattcca
     1681 tcttcacgca attgttccat tttttgacga cgtacaagca tttgatcatt taaatcttct
     1741 acttgatgtt gttgttcctg tgtcacaaaa gttcctccat tctcatgtta atctctttcc
     1801 tataatgcca atgaaacaca aaaaaagcaa gccgaacttg gaatttcggc ttgaaaattc
     1861 acgaaaaact tagaaatcac aacgtttgtt tcaatagtac tttttccgct ttttctacaa
     1921 attgatccag caggtcattg atttcttgct gtttttctgt ctgattgatt gctactttca
     1981 ctttcgctgc tcgaggaatc ccttttaaat aataagccgc atgtgttctg aattctctac
     2041 aagctacttt ttctcctttg agatctgcta agcgttgtaa atgaagttta gctgtagcaa
     2101 ttttttcggc tggtgttggt tcaggaatca gttcccctgt ttcgagataa tgctgtgtgc
     2161 ggtgaatcat ccatggattg cccagcgctg cacgaccaat catcacaccg tctgcaccga
     2221 catagtcaag catccatttt gcatcttctg gcgttttgac atccccgttc cccataaatg
     2281 gaatcgtcaa atgttttttc acttctttca atacttccca gtccgctttt ccttcataca
     2341 tctgaacccg tgtacgtcca tgcatagcga tggcacttgc tccagctgat tgtgctgcta
     2401 atgcattttc tacagcaaag acgtgctctt catcccaacc aatacgcatc ttgattgtta
     2461 ctgggatatt tactgctgaa gaaacagctt ggaccatttc gtatactttc tcaggatcta
     2521 aaagccattt tgctcctgct tctgctttga ttactttatt tactggacag cccatattga
     2581 tatctattat atcggcagct gtgttttctt cgacaaattg agcagcttca actagactat
     2641 ctttatttcc gccaaatatc tgtaaactta atggatgttc tgtttcttca atgtggagca
     2701 tctctaaagt ttttttgttt ctgaaatgaa taccttggtc actgatcatt tcacatacga
     2761 ctaagcccgc accaaattct ttgacagtga ctcgaaatgc tgaatttgtt attccagcca
     2821 tcggtgcaac aacgacacga ttagggattt ccacattgcc aattttccat gtgtgttcca
     2881 cttaaatccc tcctaaggct tctttcttca atccatctaa ttcttcttcg ctatacttgt
     2941 atttgttatt acagaaagaa caaaccgctt ctgcaccgtg atcttcgtct atcattgctt
     3001 ggatttcttc tgcacctaac gcgataattg cttctgcaaa tttttctttt gaacagtcac
     3061 atttgaattg aacaggcatt ttttccaaaa tgttcaattc ttctgtacca agcaatcctt
     3121 tcaatatttc ttctggtgtc tgtccttcat ctaagagggt agagattctt ggtgtcgttt
     3181 ttaattgttc ttcgatcttg ctgattgttt cttcatcggc acctggcatg atttggatca
     3241 tgaatcctcc cgccgtcttg atgctgtcgt cagtattgac caatacactc agtccaacag
     3301 ctgaagggat ttgttctgag atagcaagat agtaagtaaa atcttcagcg atttctccag
     3361 aaacaatcgg cgtttgccca gaaaaaggtt cttttaatcc taagtctttt gtgacagtaa
     3421 acattccttg tgttccaact gctccccgca catcgatttt accttcacta tttagaggaa
     3481 gactgagatg cggatttttg atgtaacctt tcacatctcc ctttccattt gcatctacta
     3541 caattcctgt tgctggacca tcgccttgga ttcgaacagt tagtttgtct tctcctttga
     3601 gcgtcgcacc aagtagcaga ctaccgacca atgtccgtcc caaagcagct gaggaggtgt
     3661 gccaagtatc atgacgtctt tgtgcctccg ctacggtatt tgttgcttga acggcgtatg
     3721 ctcggacgaa tccgtcgtga gcaagtgcct taaccaaata atctttcatt tgttatgtac
     3781 tcctttttcc gtttttaaac tcatagtgaa tcatactagc aactactgct tttttcaact
     3841 ttggaatgct tcttttaaaa ataattcaga atcatctaga aaacaggaca tcaccctatt
     3901 tacaacttaa ataaagaaat ctcccgaaaa ccggtttttg ttccggtttt cgggagtcat
     3961 atcagatcaa ttgacctata tttttttatt tgtattgatc gtctgaatga ttatcttctg
     4021 attgttgaga atctgaatca tgttctgctt tattttcctc attcagttca tgttttgctt
     4081 cttcaaaatc acgtttttct tccgcttgtt tttcagcgtc tttttcttcc aaagcacgtt
     4141 ttgcttcttc aaaagttttc gcttcttttt cgcttggata atcatttgac tcagtacctt
     4201 caggcatcac accgtgttca aacaatgact tgattgcttt ggcatccaat gtttcgaatt
     4261 ccaaaagttt ttcagcaatc agtttatgct gtgcacgatg agcttcgatg atttctcgag
     4321 ctttatcatg agcttccatc aagatttttc gtacttcttg atcaatctcg aaagcgactt
     4381 gttccgagta agcttttgtt tgaccatagt cgcggccaac aaacacttga tggtttcctt
     4441 catattgaac aggacctaaa cgatcactca ttccatattc tgttaccatg cttcgtgcta
     4501 gagctgtcgc ttgctcaaag tcattggaag caccagttga ttggacattg aagatgattt
     4561 cttcagctgt acgtccacca agtaagccta cgatttgttc aaacatatct tctttcgtca
     4621 tcaagaactg atcttctttt ggtaaagcga tcatatatcc gccggcgcgt ccgcgaggga
     4681 tgatcgttac tttgtggacg acccgagcgc gactcaatac taatccgaca atcgtatgac
     4741 cagcttcgtg ataagcaacc atttcgcgtt cttttttgct gattacgcga tcttttttag
     4801 ctggacctgc aatcacgcga tcttccgctt catcgatatc agaagcatcg attttctttt
     4861 tatttcttct agcagctact aacgctgctt cattcaagac attttctaaa tctgctccgg
     4921 caaaacctgg tgtctgttga gccacaactt tcaagtcaac gtcatctgcc atcggtttat
     4981 tccgtgcatg gactcgcaag attgcttcac gaccttttac atctggacgt ccaactaaaa
     5041 tctggcggtc aaaacggcct ggacgtagta acgctgggtc tagtacatca gaacggttgg
     5101 ttgcagcaat gacgattact ccttcatttc cgtcgaagcc atccatttct acaagcaatt
     5161 ggttcaatgt ttgttcgcgt tcatcatgtc cgccgcccat accggcacca cgttgacgac
     5221 ctaccgcatc aatttcatca atgaaaatga tagctggtgc gtttttcttc gctgtttcaa
     5281 acaaatcacg aacacgactt gctccaacac cgacaaacat ttctacgaaa tcagaacccg
     5341 agatcgagta aaacggtact ccagcttctc cggcaacagc ttttgctaat aaggttttac
     5401 ctgttcctgg aggtccttct aaaagtacac ctgccgggat acgggcacct aattcaacaa
     5461 atcggcgagg atctttcaga aattcaacaa cttcaactag ttcttgtttt tcttcttccg
     5521 cacccgctac atcagaaaaa cgtacgcgat tagctttttt gtctgcttct ttggcttttg
     5581 atttaccaaa gttcatgaca cggccgccac cgccaccgcc gccgccttgt tgtcccatca
     5641 tcatgtaaaa gaaaaagatg atgattacga ttggcaagaa gctaagcaat agggaaaccc
     5701 atataccgct gcttgattct tcttttactg ttgtagcaac tttgttttct tttgccagtt
     5761 ctgttacttg gctcaatgtt gtatcatttg gcaaaatgat tgttgtgaaa tgggtagtag
     5821 tcgtatctgt tgaacctaag atagctaacc caccgctgtt agcgacggtc tgctgttctt
     5881 tgtattcacc agtgatctta tatacaccat ttgcaggctg cacttcaaat tctttgatct
     5941 tgcctgcttg tagttgttct gtgaattttg agtactcgat atctgacgat cgctggccgt
     6001 tattaccaaa aatgaaataa acgaccatta ccatcgctaa gattacgagg acataataca
     6061 aggcattttt catcatgccg ttgttctttt tgttcatagt tgccctccct aagcgtcaat
     6121 ttaatttaac agttttttat caatcctgac cattctattg taccataatt taattgagat
     6181 acagcattaa tttgattgat aaacactagg tttcaataca ccgatgtacg gaaggttacg
     6241 atatgcttct gcataatcca agccataacc gaccacaaat tcatttggta cgttgaagcc
     6301 aacataatct gcttcgatat ttactactct tccttcaggt ttgtcaagta gtgtaacaat
     6361 tttgactgat tttgctttgc ggtatttgaa aagatccact aaataagcaa gtgttcttcc
     6421 gctgtcaatg atatcttcaa cgatcaacag atcgcgacct tctacattcg tatctaagtc
     6481 tttgacgatt tttacttccc ctgacgagac tgttgcattc ccgtagcttg aaacatccat
     6541 gaaatccaat tccaaatacg tatcgataga acgaacgata tctgccatga atggtaccgc
     6601 tccttttaag acacctacta ctaggggatt ggtgttttgg taaatttctg ttaactcttt
     6661 gcctagttct ttgcaacgaa cttgtatctc ttcttgtgag atcaaaattc tctcaatatc
     6721 cttttccaac atcaggttct ccttccaatt gcttcttttt gatatttgta aagaagtatg
     6781 tagtgtattt tatcagtttc ttcacgaata ctcaaatatg aaaaggcaaa aggtatcaag
     6841 ctatatatat ttcttttggc atctgtaatg atccaagcat gctgcctttg tgaattaggt
     6901 actttctgat cgataaaata tctagatact ttttttgtga gattctctgt taatttaatg
     6961 cggtctcctg cttttctttt ttcgacatac agttgcacat cagcaggaat ccaaatgtca
     7021 tgagaaaata gagaccatga atctgttgct ttgatgtccc ctgcattttc aggtttgacc
     7081 agaccaatcc attctgtttc attcaaatat attccttgtt ctggaatcag caacaagcgc
     7141 tggtcttctg tctggctagt tgcttgtttt tcttttttag agagtacaac aaaatgatac
     7201 tctcttttca gtatccaatt attgccaata ctgagttgcc attggctttt tttctgttgc
     7261 cactggtcta aaatcgactc catttgttgt tctttcaaaa taattcctgt ttttgagaat
     7321 gctttgtcga aaaaggagta aaaaaaatag tatcgttcag catctgtcat ttcttcaatc
     7381 atttctgcag aaaatcgaaa ttgttcctcc cactgttcga cttccttttc gatcaactgt
     7441 cccatatatt tttgaatgac ttggtctgcc cattggatct gttgcgaaaa ttgctggaaa
     7501 tgtctcaacg cctgtgtatt ttcttgtttc aattgaggaa ctaccaaatg acgaagccga
     7561 tttctctgga tatctaacaa ttggtttgtc tgatcctcaa agtaaacaag ctgcgattcc
     7621 gctgcataag tatataggtc ttctttgcta aaactcagca acggacgaat cagtctgccc
     7681 gtagcaaatg gttgtacttc tttgattcca gaaaaagtat ttaactgtcc cccacgaacg
     7741 attttcatta acaccgtctc gatttgatca tctccgtgat gagcagtcat caacgtgtca
     7801 tattgtcctt cttccatcac gcgagtgaat tcttgataac gaaagttacg agcttctgtt
     7861 tctatggcgg atttggctgg atcttcccaa atacttacat ataaagggag attcttctct
     7921 tcacaatatg agcgaagata ggcagcttct tctgctgatt cttctcttaa ttggtgattg
     7981 atgtggacga tacctaaaga aaaaccgatt tggcgttgca cttgtaaaag taaatggagc
     8041 aaaaccatcg aatcaacacc acctgatacc gctgctaaaa ttctcgatcc ttgttgccag
     8101 aatccttgtt cattcccgtg ccgaataaat gactgctgta atagcggtgc ttttttcccg
     8161 cctttttcaa cgttcatcct ttccacaccc tttcttccta aaaaaaagag agcgggaaaa
     8221 cgtctaaaac gacaattaac ctgccctctg ttgatactat gacccaaata gtcgcactat
     8281 cattatttgc ggctttttag ctgcgacgtc cgccacggcc accgcgcttt ccttctgtgt
     8341 ttcgcttcaa tgaagataag cggtcatcgc tatctttcaa aaatgaactc atcaatgaat
     8401 cgaagtcttc tttttgagct gaaggttgac tgcgagaaaa agattttttc tgtgctggac
     8461 gatttcggtt gtcacgggga tctttttgtt gatatttttt aggacggctt tcttctccag
     8521 attcagcagg ttgttcctgc gctttccgga tagatagtcc gatttttcca tcatcattta
     8581 ctgaaataac tttaactgtt acttcatctc ctacacttaa aacatcatgg atgtctttta
     8641 catagccatt tgacacttcg ctaatatgaa ctagacccgt ttttccagca cctagatcaa
     8701 taaacgcacc aaaatttgtg attcctgata cttttccttg cagttttgct cctacctcga
     8761 ttgacataaa aaaaatgttc ctcctaatta tttccctttt ttatattcct gcttattttg
     8821 cagttgtaga actagttgat tgatctgttt catttgtcga gctgtctgta tttgattcta
     8881 atataggata aactttttca ccgtcttttg agtaaaagaa tttgcttctg gcaagtttag
     8941 ctacatactc atcatctttc agcaatgaaa catcttggtg cagctgatca acgtctgcgt
     9001 tgacttcttt catttcagta tttgcttcga ctctcaattc gttcaattga tgcatccttt
     9061 gcatgtcatg gaaaatctgc acacctatta tcgcgaaaat gaccaaagca ccaacaaaaa
     9121 ttgcagccag tctgcgtctt cgaaaaatca gttgacgttg ttgttgctga aattcagcat
     9181 actttttctt tgcatattcc gtatctagcg cagcgatttt attgcttttt ttcgtcactt
     9241 ggattcgctc caatcttttt gattgtcttt ttcattatac caatatcgtg aaagcttgtc
     9301 taatctattt ctctagtgtt tctgtgcgat tttcagaaat aatttcgtac attttttgtg
     9361 catcttcttt tttggttgat tcatgtaatt ccgtaatttt cacttccaac gttttgttgc
     9421 caaactggac tttcaaaata tcgcctactt tgacatcact ggaagatttc gccaatttac
     9481 cgttgatttg aattcttcct ttatcagcta cttcttttgc tactgatcgt cttttgatga
     9541 ttcgggaaat ttttaaaaat ttatctaatc gcatatctta ttcctcactt tttaattttt
     9601 ttatttaatc gcaggatttt cttaccaaaa ggcaacatta gccattctcg tactgtaaac
     9661 agacgaagac gaatcactgc ataaatgaac acagaagccc cgatcccaac tcctatcacg
     9721 ctgacaaaaa aagcagtgga acgatgagtt acaggaccaa atactatatt caatacacca
     9781 taatacagca gcagtactac tgtcatacaa agaaggctga acatcaactt ccgtccaaaa
     9841 tgccgttctt tccaaaaagc atttagctct tttgtttcaa ttcgaacaaa ataccaaagc
     9901 gtcacaccta atcctaaaag ggtagacagg cttgcacctg ctgttcctaa taaaccggtc
     9961 agaaaagaag tagtcaatcc ttttaccaat agtccccatc ctgcgccttt taaagaaggg
    10021 cgaaacgagt tcttgctttg agcaatactt tgataagctt ggatgactgc agtgaaagca
    10081 atggaaaaaa caaataatac aagcgctgca tttcccgcat aatctttaaa caacgcataa
    10141 ttgatataag ggagcagcaa ggctaatccc aaagacgcag ctaatgctaa agcggtcgtc
    10201 aatctaagat agattttggc tgtctgtaaa aactgacgat agatccggtt ggtcaaatga
    10261 cgagtcaacg caggcaggaa tgtcgcactt aatgcagtgg caatcactaa acctaattgt
    10321 actaaaggct gacctcgatc atagacccct tttgctatct tcgcaccgta ttctgacagt
    10381 ccgtaaactt ccaaagcatt ttttacaaag aaagagtcga tcagctggaa aaagataagc
    10441 aatccactat aaatcgaaac cagtccgcct tctaccagaa aacgccggat caagggcttt
    10501 gacggctgtt tgaacaatgg aaaccgtcgg aagcttaacg ctcctccatg aatcttttgt
    10561 tcatagtagt gaaggatccc atatgcgcat aaaccgccaa aaacagctcc actcattgct
    10621 gccgtccctg tttggtacac cgtccatcca agctttctaa aagcaaacgc actacagaca
    10681 atcacaaaaa cacgaacgaa ctgctcaact acttgagaaa cagcagttgg ttccatcaag
    10741 aatcttcctt ggaaattccc tcgataaaaa gatagaccag gcatcagcaa aaaggtaaag
    10801 gaaactactt ggatcagcgg tttcaattgt atgtctccca tcatccaagc aatccagctg
    10861 ctaaatgcaa agacaaacaa ccacaaaaag acacctgtcc aaaatactaa gggataaaga
    10921 ttttgcaaag cttgctttcg ctcgaaagga ttctttcttt ctgcaacgta ctttgatatg
    10981 aactgcggaa gaccggataa agctaaagtc attgctatcc cataaattgg ataaacttgc
    11041 tgataaacat aaaaaccttc gtcgccgact aagttttgga ggggaattcg gtaaagggca
    11101 cttaatactt ttgctatgaa agaagcaatc gtcaatacaa atgctccttg catgacgcgc
    11161 cgcatttctt tatgatccaa atcattgctc cttcctacgc tgacagatat ttttgctcac
    11221 gcaacgcttt gacaaacttt tggatttcct gaagccatac tgcttcttcc atttggttgg
    11281 ggatcgtcaa gcgtatcacc atctgttctt tttcaacgcc tagactggct tttagttttg
    11341 tcgctgtcag tgcttcgaat aactgttcca cactatagcg ttttgttcca actttactta
    11401 gagtaaagac tatatgcgcc tcctgtttcc ttatcgtttc taggagcgct cgatcgccat
    11461 ccattttgat ctgcccaatt gtcaagagat gtgctacttc ttctggatat tctccaaaac
    11521 ggtcgagcag atcatcttct agttcatcta gcatttcttg cgaatcaagt tcacgaattc
    11581 gtttatagat ctcgattttc tgccgttgat ctgccacgta tgtttcaggt agatacgcat
    11641 cgacaccgag gtcgatctca acagtggtct tctccacttg actattcttt ccttgtttac
    11701 gagaaacagc ttcgcttagc atttgagaat acatatcgaa accgactgca tcaataaatc
    11761 catgctgctg agcacctaag agattacctg caccgcgaat ggaaagatcc cgcatcgcaa
    11821 tcttgaatcc agatcccagt tctgtaaaat ctttgattgc ctgaagacgt ttttcactga
    11881 cttcgttaag gatcttctgc tgctcataca taaagtaagc atatgcgaca cggctgcttc
    11941 ttcctacccg ccctcgcaat tggtataacg tggataatcc catataatca gcgttctcaa
    12001 cgaacaacgt atttgcgttc gggatatcta ctcctgtttc aatgatggtt gtagtgacaa
    12061 gaacatcata ttgaccttca ataaattcaa aaagcgtatt ttctaattgc gcctctgtca
    12121 tttgcccatg agcataaccg atccgtgctt ccggaacgag ttcttggatt tcttctactt
    12181 tttgttcgat cgtttctacc cgattatata aatagaatac ttgtccacct cgtcccattt
    12241 ctcgatggat tgcttcgcga atagccccag gatttttttc cataacatac gtttggatcg
    12301 gataacgatt cgcaggcggt gtttcgatta ctgaaagatc ccgcacgcct aacatcgaca
    12361 tatgcaaagt tctcggaatc ggtgttgcag tcagagtcaa aacatccact tgtgcacgta
    12421 actgtttcaa tcgttcctta tgttttacac caaaacgttg ttcttcgtca atgatcagta
    12481 gacccaaatc gctaaattca atatcttttg acaaaattcg gtgggttcct acaacaatat
    12541 caacttgacc tgtacgcagt tgttcgatgg tttctttttg ttgctttctt gttctgaaac
    12601 gacttaatag cccgatattt acggggaaac cttcaaatct ttccagcatc gtttcatagt
    12661 gctgctgtgc caagatcgtt gttggaacta aaaaggctac ttgtttgctt tcctttatcg
    12721 ctttaaaggc cgctcgaagc gctacttctg ttttcccata accaacatca cctacgagta
    12781 gtcgatccat tggtttttct ttttccatat cccgtttgat ctccgctgca cttctcaact
    12841 ggtcatcagt ttcagagtag gggaaggcat tttcgaattc tttttggtag gcgtcatcag
    12901 gtccaaaagc atatcctttt tctgactctc ttgcggcata taatttgatt agatcgtcag
    12961 cgatatcctc gatttttgaa gagacttttc gcttggtttt cgtccattca cttccgccta
    13021 gcttattgat gcgaggcgct ttggcttcag aggcgacata tttttggatc agattcagtt
    13081 gagtaacagg aataaacagt ttgtcgtcgt tttgatacaa aatagtcata tagtcttggt
    13141 gaacgccatc tacttctagc gtttccatcc caatgtattt cccgatacca tgattggcat
    13201 ggacaacgta atctcctgct tttaactcat tatagctttt caatcgctct gcgtttgtta
    13261 ctgtttgacg tctcgtttgt tttttcgtcg ttttttggaa aatttctttt tctgtgatag
    13321 ctactatttt ttcttgagga agttcaaaac cagcctgcaa agctccttca actaattgta
    13381 cctgtcctct gatcaatgca tttttttctg tttctactac taatatgtct tcatctcgaa
    13441 gcatttgttc tgctttgcgt attctgtcct ttgtcggaat aaagatcaca acagtctgtt
    13501 tttgcttgcg ccaacggtcc atttctgttt tcagcaatgg catttgtccg aagaactgtt
    13561 gcatcgtccg atattgaaaa ttatggattg cttggaaacg aagatttccc atcccttttt
    13621 ggaagagtga gaaaaaggtt gtggtgaact tttccttctg cacgattttt tgtatatctg
    13681 ctgaaaatgt ctgctcagaa aacacccgca attcgctgat tttttgagtc tgccattctg
    13741 ccgcttccct ttcgatttcc cgatttgttt ccatgattcg ctgataatca tcaacgacta
    13801 gtaaactatt tgaagggaaa taatccaaga tcgtcacaga ttcttggtaa agaagatctg
    13861 agtagaattt tgcttcttct gtcgggacac ctgcttgcca gcttgaagtc agctgaccga
    13921 agtaatcttg caaaaactcg cggtctgctt cttctgtggt cgcagcaagc cgtttttcta
    13981 gcattttttg catttgctct attccatgtt ctagatcctc tggtccgtag acttgttcac
    14041 tcgttgggga aacccagatt tcttccgttt tttcgattga gcgttgtgtt tctgcttcaa
    14101 aataccgcat agaatctatc tctacatcaa atagttctac acgaacagga taggttgtcg
    14161 ttaacgggta aatatcgata atgcttcctc gaatactgaa ttctcccggt tttgcgacca
    14221 tctcttctcg tacatagccc atcaaagtca attggcgagg aagattttcc acgtctatct
    14281 catcaccaat atgccaattc aattgcgcct gtagccaagt tttcttattc ggcagtcgtt
    14341 tgtgcaaaga tgcgactggc aacaaataga tacctgcttt tttttcttga agtgcgttaa
    14401 gcgttgcaac tctctcgcct cgcgcttctg gagaagaaaa ggccatttca gcagaaagca
    14461 cttcatccac tggaaataaa tggatctgat cttgcggaat cacatgttgc agatcttctg
    14521 ctaactgatt cgcataatac aaatttggca tcagaataat catgttttta tttgttttct
    14581 taaacgctcg agcaaataga agtgttttcg ctgagcccgc taatcctgtg attagttgtc
    14641 taggcatttt ttcttctaaa ttgctgaccc attcttttac ttgcggatct tttccgacta
    14701 attgaataat atccattcct tttcctcctt cctcaattga atcgattcat cgcatccacg
    14761 aacgaatgcc cttctatgag atattcgact gctttaacag attgacacat gctttcttct
    14821 atcaaaggct gattttcttt gctgaaagga ctaagcacat gctggactac tgtttttttc
    14881 ccttctggcc tgccgattcc caccttgatt cgatcaaaga cattcgtatt caaatgggaa
    14941 ataatacttt tgataccgtt atgcccgccg gcacttccct tttgacggag ccggattttt
    15001 cccactgcca gatccaaatc atcgtagatt acgactaatt cctctggata aatcccaaaa
    15061 taagtcatta gtgggccgac tgcacgacca gattcattca tgaatgtttg tggtttgact
    15121 aaaaggatct tttctccatt atgaaaaaat tcggcaactt ctgcttcgaa cggatttttt
    15181 ttgaaagtag cttgatgctc gcgtgcaatt ttatccacga ccataaagcc gatattgtgt
    15241 tttgtatatt ggtatttggt acctgggttt cctaacccga cgatcatttt catttttgtt
    15301 ttccacctaa ttctaaaaag cagcacaaaa ggctggactg ctaattagcg gtccagtcca
    15361 tcgagctttt ttctttttta cacttgtcaa tgcatagtat aacacaaaac aaggcgtttc
    15421 ggctaaaaga gaatcgttaa taaatgataa agaaattaaa aatttcttca aagtttaatg
    15481 aaataattga tatataaaaa tagtgaaata acgcacatgt aagcttttac atataataca
    15541 accttgttat ctgttatatt ttatagccaa atagcgtgac atggggcttg agaaatgtta
    15601 gcataagcat gggaaaaaac aaatcaatgg aaggattgat actaaatgac tgcagctgca
    15661 gaaaaaaaag atcatcaaaa agttattctt gttggagacg gcgccgtagg ttctagctat
    15721 gcctttgctc tagttactca aaatatcgct caagaagtag gtattgtgga tatcaatact
    15781 gctaaaactg aaggagacgc aattgacttg tctcacgctt tggcatttac ttcacctaaa
    15841 aaaatctatt ctgctactta cgcagacgca catgatgctg acttagttgt tattacagct
    15901 ggcgcaccac aaaaaccagg tgaaactcgt ttagacttag taaacaaaaa cctaaaaatc
    15961 aaccgcgatg ttgtcacaca aatcgttgaa tcaggattta acggtatctt tttagttgcc
    16021 gctaacccag tagatatttt gacttactca acttggaaat tctcaggttt ccctaaagaa
    16081 cgcgtaatcg gttcaggtac ctctcttgac tcagctcgtt tccgtcaagc acttgcggaa
    16141 ttagttgacg ttgatgcacg taacgtccat gcttacatct taggtgaaca cggagattca
    16201 gaattcccag tttggtcaca tgcaaatgtt gccggcttgc aaatctatga atgggtaaaa
    16261 aacaacccag aaatcgatga agaagctatg gttaacctat tctttggcgt acgtgacgct
    16321 gcttacacaa ttatcgagaa aaaaggcgct actttctatg gtatcgcagt agcattagca
    16381 cgtatcactc gtgccatctt agatgatgaa aatgctgttc ttcctttatc agtattcatg
    16441 aatggcgaat atggattgaa cgacatctac attggtgcac ctgctgttat caaccgtcaa
    16501 ggtatccaaa aagtaatcga aattccttta agtgacagcg agcaagaccg tatggctgct
    16561 tctgctaagc aattaaaaga aattctagat gaagcttttg ctaaactaga cgctgaataa
    16621 tctttgaaca tgacggaaaa catctattcg gtgttttccg tttttttatt ttatcaccct
    16681 tatggtttct aaattttttc ataaagtaga gataaccttc gtcttttcct ctaaattatg
    16741 ctatcatgag accgttccac cctaaacttt tacttaagga gttgtcgata tgacaagatc
    16801 ttcgcatcga aaaaaatcga aacatgttgc tttgctttca gttcttggtg ttctcttagt
    16861 gctgatcagc ttttatacct atcgcagtac atactacaca aagcattttt tgccgaatac
    16921 agaaataaat ggaataaatg tcagcaatct aacagtcgaa aaagcaaatg aaaaattaaa
    16981 agaagcttat tctgataaaa aactggctat taaagaagat ggaaaagtct ggcaggaagt
    17041 accaaaatcc gagctcggct acaaagatga tttcacttcg gagctttctc cgatcctaaa
    17101 tgaacaaaac ggatggactt ggggaatgac ttatgtctca gcggcagaaa aacaagaaat
    17161 agatcctgtc agtcaaaacc accaaaaact agacactacc gttcagacat tgacaactaa
    17221 gctgactgat ttgaacaaag accggacacc tactactgat gcaacgatcg aaaaagcagg
    17281 tgactctttc gttatcaagc ctgaagtcaa tggaaatacg atcgacgtcg atgctgcggt
    17341 caaacaatta aaaagtgcgg taaactctgg taaagataca attgaattga ctgaattcaa
    17401 agaaaaacca aaagtaacat ctgaagacag ctcactgaaa gaacaactcg catccatgaa
    17461 tgctatcgca aatgtaaaag ctacttacag tataaacggt gagactttcc agatcccatc
    17521 aagtgatatt atgagttggc tgacctacaa tgatggaaaa gtcgatttag atacagaaca
    17581 agtacgtcaa tatgtaacag atttaggcac aaagtataac acaagtacga atgacacaaa
    17641 atttaaaagt acaaaaagag gagaagttac ggtcccagtt ggcacttaca gttggacgat
    17701 ccaaacagac agtgagacag aagcattgaa aaaagcgatt ctggcaggcc aagattttac
    17761 tcgttcaccc attgtgcaag gtggcacaac cgctgatcat ccattgatcg aagatacgta
    17821 tatcgaagtt gatctggaga accagcatat gtggtattac aaagacggaa aagtggccct
    17881 tgaaacagat atcgtttccg gaaagccaac tacacctaca cctgctggag tcttctatgt
    17941 ttggaataaa gaagaagatg caactttaaa aggaacaaat gacgatggaa caccttacga
    18001 gagtccggta aactactgga tgccgattga ctggacaggt gttggtatcc acgattcaga
    18061 ctggcaacct gaatacggtg gagacttatg gaaaacccgc ggttcacacg gctgcatcaa
    18121 caccccacca agtgtaatga aggaattatt cgggatggtc gaaaaaggaa cgcctgtatt
    18181 ggtcttctaa caaaaataat atataaaaag aaagcacccg tacgattggt acaggtgctt
    18241 tctttttatt atctaacaat gtgctactta catttcagca gcagtaaaga cttctgaaac
    18301 atcatcatcg tcttctagct tatctactag acgttccaat tgctcttttt gttcctcatt
    18361 taaatcaatc gtcgtttgtg gaatcatcgt caattctgct tgcgccaaag tgaactcttt
    18421 ttccaactca tctcgtacag cagcaaaatc ttctggtgca gtataaatct cgaatacttc
    18481 aggagaagtt tgcagatctt ctgcccccgc ctctaataca tcctcaaaca tcgtctcttc
    18541 atcaacagtc aacccatcgc gttcaatagc gatatatcct ttgcggtcaa acaagtaact
    18601 gactgaaccc gtttctccca gtgatccacc gtttcgagta aaagctactc ggacatttgt
    18661 cgctgtccga ttacggttat ctgtcaatgc atggactaag attcctactc cacccggacc
    18721 atatccttca tacgtgattt catcgtaatt cgtttcatct acggcactcg tagccttttt
    18781 aatcgcccgt tccacattgt cgttaggcat atttgcagct tttgctttgt ccacaacaag
    18841 ccgcaaagct ggattcatag atggatcagg accgcctgct ttagctgcca tataaatttc
    18901 acgagaaagt ttctgaaaga ctttccctcg ttttgcatct tgggcatttt ttcttccttg
    18961 gatattatgc catttactat gtcctgacat gatttttcct cccttgttct tttgagaata
    19021 cacttctatt ctagtactat ttcacaaaaa aacaaagcca cagccaatct ataaacgctt
    19081 cttgaatgcc gcaaaaagca cacataatat cacagcagtc agagcaccga tcgaatccaa
    19141 catgacatct tggaacatag gtgttcgtcc accggtcatc atctgatgga attcgtccaa
    19201 acctgcgtac cctgttgctg aaagccaagc aaggatcgct gtcagccacc aaatttttag
    19261 cttggggaaa acacctaaaa acaagctgcc tcccaaaata aaataggtac cgaaatgtgc
    19321 gcccttcctt aaaaagaact ctaaaaattt ggcgtagccc agatggttga tactcaccat
    19381 acttccacca taattaaaac gtatacccgc taatgtgtct ttaaatggct gattaggcag
    19441 ccagctttct aatcgcgaaa cttgtgattg ctgtccgtaa gtttgagaag aactgtaaaa
    19501 taagattata acgactatca gtgcgattac taaataaata tttccgtttt tcatttgttt
    19561 ttttgaagaa ttcataagtc acctctgtat tttatcttag actttttttg aagaaacaac
    19621 aatcattttc atagagactt cttccataaa aaagtgctat acttaatttt gtattacaat
    19681 atgaagggag ttttttcatg agttattcat taaattggaa tctagattct attttttccg
    19741 gaggcagtca ttctgatgct ttgaaccaac ggatgaagca attggaagac caaatgaacg
    19801 agtattatca ccgcgtaaca aaatggtcac ctagttctga caatgcagag cagttaaacg
    19861 ctattcttca attgcaagaa acgattacga atggttttac ccaatgcagc agctatatta
    19921 ctgcattgct ttctgccaat gtcaatgatt cagatgcaaa ggtcttatca ggcaagcttt
    19981 acgcaatgct gcctcgtctg caatcagccg aaactgtatt gtcaaagaaa tttgcagaaa
    20041 tatctgacaa tgattggaat cagatgcttt ctcaatcttc gtttgaaaca attgcttttc
    20101 gtttaaacga gattcgtcgt gatggctcac aattattatc agaagctgaa gaaaacatta
    20161 taaatacgct ttctttagat ggtctaaatg cttggagcag tcattatgat acgattgtag
    20221 ccagcatttc gattcccttc gaacaagatg gacaagtagt cgaattatct gctggacaag
    20281 ccttcaataa gatgatgggc gatccagatc caaaagtcag agaaacactt ttcgcagcat
    20341 gggaagaagc ctggaaagaa aaggcacccc tcttcacgga tactttgaat catttagatg
    20401 gttttagact ttctgactat gaacttcatg gtgtcacaga ttttctacaa aaaccattag
    20461 agtacaatcg gttgaagaaa gaaacattgt ctgtcatgtg ggatacaatc cagaaaaaca
    20521 aacaacccct tgttaattac ttgactagaa aagctaatct tttcggtaaa gaaaaaatgg
    20581 aatggcaaga tcaagatgca cctattattt taggcgattt gaaagaaaaa acctttagtt
    20641 ttgacgaagc agcagcattt attatcgaaa actttaacaa attcagtcca aaaatggcta
    20701 aatttgccca atctgctttt gaaaagagct ggatcgaagc agaagatcgt cctgggaaac
    20761 gtcctggtgg ttattgtact gagttaccag aaacaaaaga atcaaggatc tttatgacct
    20821 acagtaattc tgttaatgag gttgcgacac ttgctcatga actaggacat gctttccata
    20881 gcagcacgat gtgggattta ccttctttaa atcgcgaata tgccatgaat gtcgcagaaa
    20941 cagcaagtac attcgcagaa ttgatcgtag ccgatgctac attaaaagtc gcaaaaacaa
    21001 aagaagaaaa aatcaatttg ctagatacaa aactgcaaaa tgctttagct atgttcatga
    21061 atatccattc ccgattcatt tttgaaaatc gattctatga agcacggcaa gaaggattag
    21121 tctcagaaga taagatcaca gagatgatgg ttgaggcgca aaaagaaggc tatcaaggag
    21181 ctttagctac ttaccatcca tatttctggg ctgcaaaatt gcatttcttt attgatgacg
    21241 taccgtttta taacttccca tacacatttg gctacctctt tagtttgggc atctatgctt
    21301 acgccaacca aaagggagca aattttgaag aagaatatat ccatttacta cgcgatactg
    21361 cctcaatgac gacggaagat cttgcgaaga aacatttgaa tgtcgatctt acccaaccag
    21421 atttttggca agcaggtatc gacatggtga ctgaagatat ccaaacgttc atggaattga
    21481 cagaagaatt tatctgattt ctattttatc acaataaaaa aagagttagt ccagaatggg
    21541 ctaactcttt ttg
//
LOCUS       DAFLWC010000052        21360 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.053, whole genome shotgun sequence.
ACCESSION   DAFLWC010000052 DAFLWC010000000
VERSION     DAFLWC010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21360
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.053"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..2327)
                     /gene="esp"
                     /locus_tag="L1V17_001747"
     CDS             complement(<1..2327)
                     /gene="esp"
                     /locus_tag="L1V17_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HBN1236515.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
     gene            complement(2944..3378)
                     /locus_tag="L1V17_001748"
     CDS             complement(2944..3378)
                     /locus_tag="L1V17_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236516.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(3395..4600)
                     /locus_tag="L1V17_001749"
     CDS             complement(3395..4600)
                     /locus_tag="L1V17_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HBN1236517.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            5294..5680
                     /locus_tag="L1V17_001750"
     CDS             5294..5680
                     /locus_tag="L1V17_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBN1236518.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            5774..5965
                     /locus_tag="L1V17_001751"
     CDS             5774..5965
                     /locus_tag="L1V17_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1236519.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            6479..6811
                     /locus_tag="L1V17_001752"
     CDS             6479..6811
                     /locus_tag="L1V17_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1236520.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            7107..7262
                     /locus_tag="L1V17_001753"
     CDS             7107..7262
                     /locus_tag="L1V17_001753"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HBN1236521.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            7538..8878
                     /locus_tag="L1V17_001754"
                     /pseudo
     CDS             7538..8878
                     /locus_tag="L1V17_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(9119..10735)
                     /locus_tag="L1V17_001755"
     CDS             complement(9119..10735)
                     /locus_tag="L1V17_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBN1236522.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKKIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            10853..11071
                     /locus_tag="L1V17_001756"
     CDS             10853..11071
                     /locus_tag="L1V17_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1236523.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            11266..11727
                     /locus_tag="L1V17_001757"
     CDS             11266..11727
                     /locus_tag="L1V17_001757"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBN1236524.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(11920..12159)
                     /locus_tag="L1V17_001758"
     CDS             complement(11920..12159)
                     /locus_tag="L1V17_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1236525.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(12183..13706)
                     /locus_tag="L1V17_001759"
     CDS             complement(12183..13706)
                     /locus_tag="L1V17_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBN1236526.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            complement(13724..13846)
                     /locus_tag="L1V17_001760"
     CDS             complement(13724..13846)
                     /locus_tag="L1V17_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBN1236527.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            complement(13876..14859)
                     /locus_tag="L1V17_001761"
     CDS             complement(13876..14859)
                     /locus_tag="L1V17_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBN1236528.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(14883..15032)
                     /gene="rpmG"
                     /locus_tag="L1V17_001762"
     CDS             complement(14883..15032)
                     /gene="rpmG"
                     /locus_tag="L1V17_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBN1236529.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(15053..15430)
                     /locus_tag="L1V17_001763"
     CDS             complement(15053..15430)
                     /locus_tag="L1V17_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236530.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(15462..15641)
                     /gene="rpmF"
                     /locus_tag="L1V17_001764"
     CDS             complement(15462..15641)
                     /gene="rpmF"
                     /locus_tag="L1V17_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBN1236531.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(15656..15925)
                     /gene="rpsN"
                     /locus_tag="L1V17_001765"
     CDS             complement(15656..15925)
                     /gene="rpsN"
                     /locus_tag="L1V17_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBN1236532.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(16448..18214)
                     /locus_tag="L1V17_001766"
     CDS             complement(16448..18214)
                     /locus_tag="L1V17_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1236533.1"
                     /translation="MQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(18174..19928)
                     /locus_tag="L1V17_001767"
     CDS             complement(18174..19928)
                     /locus_tag="L1V17_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1236534.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(20038..20607)
                     /locus_tag="L1V17_001768"
     CDS             complement(20038..20607)
                     /locus_tag="L1V17_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HBN1236535.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(20625..>21360)
                     /locus_tag="L1V17_001769"
     CDS             complement(20625..>21360)
                     /locus_tag="L1V17_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1236536.1"
                     /translation="KTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKD
                     INFDVKVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDY
                     QFFTESVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASL
                     SKTNLFLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKN
                     GGIKKDIKLRVEDSTLIEQIFNDITK"
BASE COUNT         6851 a         4038 c         3133 g         7338 t
ORIGIN      
        1 cctgcggtga aggttacttt gtggtagcct gcaggaatgt tttctcctgg attttcataa
       61 atatctttac ttacagttac tgctaaatcg gtcgtgccta cagaaccatc ttggtaaaca
      121 attttaatag gaattgttcc agtaatcggc tccgattctc ctacaccttt agctggagtg
      181 aatgtaacaa taccagtgtt tgcatcaaca cttgcattac cgaagtactt attatagaca
      241 tctgaaattg aaaaggcatc tttagctaaa ggaacatctg gtttatcaaa tgtaggtttt
      301 ccactttgaa ctgtcgtttc tggagttgtt gttataggta cgtatgttgc atcattttcc
      361 atagcttgag aagcttttac agcaaactct acatccacgt cgaaagttcg atttccgatc
      421 ttaacagtta caataccttt cgtactatca gtaacgttag aagtatcagg ctctgttttc
      481 catgaatact ctgcatcttc aggtaagttt ttattattcc gaattgattc tttagcatct
      541 ggtttaaatc caactaccac ggtttgttta tcaaccgctt ttggtgattc cttaataacg
      601 gttgaacctt cttctggttt atcaaaacct ggagaaacga tttggatttt taattcatct
      661 ttcgcgatta atttacttga atctacaccc gtaaattcaa attctacagt atctgaaatt
      721 ggagccccat ctttttcatt tggagcgata gttttttctg ctaatacagt accttcttta
      781 tcaacaagtt gggctttgtg acctgttccc gctaactcgt ggatgaatac tttcccctta
      841 actgttgtgt caacatcata tacttcttct aattcaggtt tcccgatata tggattcgtg
      901 tctccgctct cttctttatc gtcagggttt ccatcaccat caatatcttg caaataataa
      961 taacctgttc cataagtgtt ctggattaat tttttattcg tatccgacaa ccaagaatca
     1021 aagatgaaat cttcaccaaa tggtttattt tcttcaactt gtgctgttgc tttcatatct
     1081 tctaagattt catctaatgg cttagtcaat tgtaaaacat atcgaataac gactggacgt
     1141 ggacttgcat tagcaaaatc gataagttta gttaaatcat tattagttat tgaacctatg
     1201 ccataatttt catgaccttc ccgtcgctcg attgctaaat cagctacttt tgttccggat
     1261 tcaaacgaaa catcatatgt tactttgtca gcctgaacca tgtgcatctg tatacccgct
     1321 acatatggaa ctaatcgttc atcaattttg taattagcat accaaggcgt gccctttgcg
     1381 gaagatgaat atgagaaatt ataatttttc gttaacttat gatctaagat tatagctcca
     1441 ttagcacctg tggatcctga accatctttt gtttgagtat taggtttctc atattttgca
     1501 cttactgatc catgtttaaa ctggtcagga ttattttcag atacatctaa gctattatag
     1561 aaatcatctg aatctgttaa aaagtagccc gtactatcaa tacccggtac aattttatca
     1621 tcgtcttgat gacttaccaa gtagattcga tacattaaac gatcggtctt gagattgtct
     1681 atgcctatct ctttaaaaat ttcatctagg ctcttttcaa acgtaattac cccattagga
     1741 gcggtttgcg tatcggttgt ttctgcccca gcaaataatc catcacttgc acgaatataa
     1801 ttgaccttcc aaatatttgt aggtctaccc agcgaatcat taattcttac aaaggtccgt
     1861 ctagaagatc caattccttt ctttggatcg acctgaattt tttctacata tttagctaat
     1921 cgttcatcta attgaagacg gatttcccag tttttagttg atgctgcaat attatgtttt
     1981 ccgtaaactt caaatccaat tgtattgcct tttagtgtgt ctccagttag ttcttgagga
     2041 ctaaattgta aatccgaaaa gttataattt ttcgtataac caggattctc ctgaaaagta
     2101 ttccccgaag ctactttgtc acctacttgt acggagctta tcgctgtttc aagtgggctg
     2161 cttggagaaa tttcatcttg tgctttaact agttcagttg ttcccaagac aagaccaaca
     2221 ccaatcaaaa cagatgcaac cccaacactt aattttttga tactgtactt caatactcgt
     2281 ttctttgttt tttctagaaa tactctctta ttattcttgc taaccattat tcaaatcaac
     2341 tcccttaata attactttcc tagtaagaat aaaagataaa tctgatacgt attattcaca
     2401 gaataggaat cttactaacc ttatgttaac taatttactt agagaatttc atgaacatta
     2461 caacaaaaaa agtacatttc ttcatgtttt tttcggatat ttgtgctttt taaccattca
     2521 gcagctgaaa acatataaaa agatatgtat gtattctttc tgaaattaag ttcatttcta
     2581 tgcgatgaag catgttttca aaatattacc ctttcttaga ttaaacttca gagtattcaa
     2641 ataacggaat aaggagcctt atcccgcatt actgaatgag actgtgacat aagtaaaaag
     2701 gtgacttcaa attccttctt cggaatttga aatcaccttc tttataatta taaagtatcg
     2761 gtttcacagc atttctgaat gattcctaga atcttaaacg aatgattgga gttatcaaca
     2821 ttttttcact cgtttttagc gaaacaaaaa atgacatttg tcacagcctc attaaattat
     2881 tgattctttt tctttataat tgaattgtcc atatttaaag tgtctagtac tctacatgaa
     2941 taattaattg ctttcactca aatacttata atctattaac ttgtagttgt ttaacttttc
     3001 tgaaaaagtt agacccacgt aataatcttc ccagctttct ctttcaatta actgatccaa
     3061 tttttgataa tccataaatt catcatgtat caaaaagaat aaataacttg atattttagc
     3121 atctagctta atcagattaa ataatgtttg tttaaaattg ctaccattaa tatgactgat
     3181 agattctcta gcttcttcac ataaactttt tactttatta attactactt tgtcatattc
     3241 atttaacaca ctattattac cattacttag acgctcagat tctacgaaac aactcaaatc
     3301 agaaatttcc caaaaaaatt ttttgttaaa atccaatttc ctcaactcct ccaaactacg
     3361 taaatgatat agtctcataa taaaataaaa cctctcagct aatgttgttg aaattgtcca
     3421 ctaaacctaa ttgatattgc ttaggagata cacctgcgta ctttttgaat actctcgaaa
     3481 agtgtgaaga atctgaaaat cctaaaccta aagaaacttc actgatagta tggtttgatt
     3541 tcaacattat tttagccgta gaaatttttc gcttagagat ataattataa atcgtaatat
     3601 gcatttcatt cttaaagctt tctcttaatt tagtttcact tacagaaaaa taattagcta
     3661 tttcctttac agtaattctt ttatagatat ttaagccgat gaattgaacg acagaagaaa
     3721 ttaagggaga aagatgctct atcttagttt ttccgatttc cttagtataa taaacaatcc
     3781 cagaatccct cacttttaag acctcaggta acgatacagc taattcgttt tcttgtatca
     3841 aagcatctct actttgatac gcttctatta tatccattcc taatgttata gacgtttgtg
     3901 ctaacttttc aaaaacaatg atagaataat ttttttcaga ccgaatcgta tctccactaa
     3961 cacttggaat tattccatta ctcagattaa aaaccatgtt ttctaaattt cgaatatctc
     4021 catttttaac atattccagt attttatttt cataaagaaa cagatatatt tctggatcgt
     4081 aattttgtga taacagatta tctattttga tttgctcgat agttttactt agattttctg
     4141 tatattcaat taacggttca tggaatagat cttctatttt tccagtaaaa aaataatgaa
     4201 ctaaaatcag aatatctcga atgtctccta aagaatacaa agtcaaattt tgcaatgaat
     4261 tatagagtcg ttctctatca gccattgcaa cattcaaatt gttcattttt agtttaaaaa
     4321 aaactttatc aatattattt gctctaaatg gaccaaataa gtaatatctg gttttaaaca
     4381 tgtatagaag aaacatctca ttaaaatcac cagtaaagaa atggaaatct ttagtttttt
     4441 taatattatc agttagtaac tttttataat cataaaaaaa ataagtagtt ctatctgagc
     4501 gatactcttt tataatactg aattcggaat taaaaaccac gataggtaac tttaaacaaa
     4561 catgaagaga ctttaataag acttctttat ctgaaaacac ttttgtttct ctctttcctt
     4621 tctacatcat taaatagtat tttatacgtt atctaaaata ctattcctct gtcaaaataa
     4681 gctaacttac ttcattataa aatatccact tatcgctttc atgtatattc caccgtaaaa
     4741 agtacatttt atcaccgaga actcatcatt tttcatcatg atgaatacta tttacatata
     4801 tctagttcaa agacaataat tattatgatc cgttattatc taagcactat acagataata
     4861 ggaatttttc gtttctaaat attccaattt gggaatccaa taaaaatttt cgttcaaata
     4921 cgtgtctatt cgaactcttt tctagttgtt aattatgaag ggggaagaaa taaaaaatac
     4981 aatctataca cgaataagaa tattatccaa aaggaggttt tagaaaagat ttattatacg
     5041 taaaaagctc aagacatttt cttagccata aggacatgtt tgatatttaa gaagatatat
     5101 gaattttctt ttctaagtat aaagataact atccattatc aactaaaaaa acatttttga
     5161 aaataaacat cagcagtcct atcaatgcat gtgagcttat agaagttatt cgcagcgcag
     5221 cataattgca ttagcttctt ttcgtgtttt ttgcctcttt tccctttaaa tcttaatgga
     5281 ggaggtgtgc aatatgtcag ataacgacga acgcgtaaat gcccagttga ttcgattctt
     5341 tgaaaaggtc attttgaaca ccgctaatac ttattataaa aaacaagaag aaattcaaaa
     5401 acatgaacaa cttgatcaac tcccaccata tttgtttact aaagatacta taaaatttaa
     5461 acaaccgatt aatgttttaa atgtgactct ccttgttgaa gatataaaat tagcaaaaat
     5521 ccttcctttg ttgaaagaac ctgaacaaat ttttcttatc gaaaaattta tctttgataa
     5581 aactgataaa gaaattggaa aggttctggg gattacaaga cagggtgcga caaatttaaa
     5641 acatcgactt tacaaaaaaa ttcaaaaaat gctggtttaa tatctgcata ataactaatt
     5701 ttgtatgctt ctttgctcgt tctcctcctt cccaaagaaa tagattataa gtccatggga
     5761 agaaggtaga tttatgaatt ctttaaaaga agatttcatt ttagcaaagg ctggaaatga
     5821 agaagctgtt gaggcaattc tcaaaagatt tagctctttg attcataagc aatcctggag
     5881 aactggaaaa tatgatcaag attgttatca agaatgtatg cttgcaatat atctagctat
     5941 ctcgaaattc gaaattaaag aataactcaa ctaagggagt ctgtgacata agtaaaaaga
     6001 tagtttcaaa tttcgaacaa taaatttgaa actatcttct ttataattat aaagtatcga
     6061 ttttacagcg ttctataatg attcatagaa tctaaaacga atgattttaa ttatcaacgt
     6121 tttttaattc gtttttagct taaaaataac ttttgtcaca gtctcactcc taaaattact
     6181 ttatttacgt atgaagtggg caggaggtcg aatccagaac tgggctatgg tacttcaacg
     6241 aggacttctc ctctagaatt gaaaagcatg cgatttacct tccgtaacga cggtagattt
     6301 attcaactat gtgtccaatc aaaatttgtc tgatttcaaa aatagtcaag agaattttgg
     6361 ttgttaaaaa ctcttatcta tcaacttcca cagtttagtt gacaaaccct gatactaagt
     6421 tgggctatga tacacttttc ttgactatca gttacgttac cggaaggaat gaactctatt
     6481 gagaaaaaca tatgatcgta aatttaaact aaagatttca caggatatcc ttgagaaaaa
     6541 agtaactacc aagaaaattg ctgaagaata caatatctct cgtccaacaa tttcccgatg
     6601 ggtttcagaa tatcgtcgat acgggaaaaa tgcttttgct ggacaaggaa aaagattacc
     6661 tgataaagca gatttctaca ttcttgaaca ggaaaataaa cgactaaaag aggaagacga
     6721 gtgttctacg aacacaaaga tcgatacgga tctccaggga tcactcaaaa actttacgat
     6781 gaaggaatcg aaatcaataa acgtgttgta gctgttctta tgcgtgaaat gaatttatgc
     6841 acaagaggat ttcatcgacg caaatcttct catggtagag aaaaaacaat caaagaaatg
     6901 gtaaaaaaat gttgaatcga taatttgaac agaaccaaat tgatgctgtt tgggtgatgg
     6961 atattactta cattccatgt aatgacggtc gcctctattt gtccacctat attgacttag
     7021 caactcgtat tctacgttac tatatggtag attcacacat gaaaaaagag attgtcgtcc
     7081 gtccattaca aatttattaa ggagaattgc ctacggtaat tcattccgat agaggtagcc
     7141 agcatcggtc ttttatttat caagagctgt tgaacgacca ccacatcaca cattcagtga
     7201 gccaaactgg gactcctgtt gacaatgcag taattgaagc gtttcatcga tcaatcaaat
     7261 gagaattaat cgactccaac aaatataaaa gtaaaataga gatgaaggtg ttaatccaag
     7321 attatttaga agactactac ccaaacaaaa gaatccatac aaaatttatg atgactcctt
     7381 gacaatttga agcgaagaaa ataagggatc tataatatct agtgttggtg acgccttctg
     7441 ttgccaatac tttttctttt ttctaataaa cgcaaacaga caccttaaaa tcctttagaa
     7501 taaagtcgac gaaaaccatt caaaggagtg tttcaagatg tcctattcag agtttaccaa
     7561 agagttacta gatattctag acctaaatct tatctttcat gaagatgcct ttcgcaaaga
     7621 gcgaatcaat gacgaaacat gttttgtttt tgatggcaca ttgacctatc aaccggagga
     7681 atgctttcat cgccactatc aaaatgaaca aacgatcatt aaatagggct ggaaaaaagt
     7741 atccatctta ttgaatgatg tcagtaacta caagaccatt ctgcggatta acaaacagcg
     7801 cttcaaatgt aaacactgtg gaaagacttt tttagcagaa gattcagtta gtgatcgtcg
     7861 ctgctccatt gctcgcagag tcaaacaagc cattcttgag ctattaagcg aacctctttc
     7921 tatgtctttg atcgcacgta tgaagcacat ttctccgacc actgtcattc gaatacttcg
     7981 cagccttcgg cctaaaacca tttctttgag ccagctgtta ccagaagtgg tgtgtttcga
     8041 tgaattcaaa tcagtgaaaa atgtctcggg agccatgagc tttgtcatga tggacggcaa
     8101 gacccatcaa ctgattgata ttgtggaaaa tcggcaactc aatcctttac gcgactattt
     8161 cttgcgctac cctataaaag tccgtgaaca agtgcgtcta gtggtttcag atttctatac
     8221 accctatcgc acattggtga aagagtgttt tccgaatgcc cgaatcgtcg ccgatcgctt
     8281 tcatattagc caacacattg gtcgggcttt taccaaccac cgaattcaag taatgaagac
     8341 ctttaaaaaa ggggatcgtc ggtcgaagca cttaaagaaa tactggaaac tacttcaaaa
     8401 gaatgcgtgg gaattgaaag gtcagcatcg ctactggcgt ccgtcatttc gagatcatct
     8461 gacagaagca gagatagtcg atcggctatt atcttatgat gattccttaa agcgaggcta
     8521 cgaagtctac caggattttc tttccgttat cagaagacaa gatgttcctg aattcgtcgc
     8581 gctcctaaaa gaagactaca aggagttgcc agagcactac caaccagtgt tcacgacctt
     8641 caagaaatac caaacagaaa tcaaacgagc gttgcgcgtt ccctattcca acggccctat
     8701 agaatgtttg aataaccata tcaaagtact aaaacgaatt gcctatggct atagaaactt
     8761 tcaaaactac cgagaacgaa tctttttata tcgaggaaaa tattttaaga aaactaagaa
     8821 tactacccaa ctgactaaag ccagaacaac aacacggcta gacaagatag ctgtctagcc
     8881 gtgtgagtat ctcgattatt ctattgaatt tcttcaccaa cactcattga cgaagagcca
     8941 aaataagtaa tctaaccgac tgttaactaa accattgcag gtcccgttaa agatacttgt
     9001 gcctgttgtc accgcttctt tttcttgtcc acaagcgctt aacacactta ataaagcccc
     9061 tgctattatt aataataata tctttttctt attaaaaacc tcctcatcta tttccagatt
     9121 agtaaatgta gtaatctgtg ctttcttttt tctcaatact aataactaac ttatggggta
     9181 aacaaatact cgtttgaccg ggttttgaga tccatccagt tctaaccgcg atttgatcag
     9241 gactattatc ttctttaact cgaattcttc catctttaat ctcaacaata ttatattgtc
     9301 ccttcgcagg atgataattc acgagtttat gattgatctt atccaaatcg aagcgatcca
     9361 tttccttgcc atcaattcga acgatggcat atttgatagc atcttcagtt gtttcattct
     9421 ccttttctat agagaataca aataagggaa taaaagaggt aataatcaaa atgccaataa
     9481 ttatgacatc gcctatcttg acaccagctt ttcttaaaaa tttcattaac gatatctggc
     9541 taaacatatt agactttttc catggaaatg gtgaaatttt tcggaaatta tctgcattaa
     9601 gagaatcagt taaacaaccc tcaagttgtt ccttaataca ttgttgatcc atcttcatac
     9661 caataaaaac tagtttatta atgcgttcac caaacaacgg atgccaggct tccttcaatt
     9721 cgggattttt ttgtataatc atttgacact caattttagg taaactagct acccaataat
     9781 ttaatgattc aatactttta tagctacccg atgtttcaaa gatcgtcgaa aaatcactat
     9841 gttgggcaaa ccaaagaaac ccttttgctc ttgtaatatt gccaggaaaa tttttatccg
     9901 taagatgggc aaatttttgt gcgtcaagga gtaaccgatt tcgatagata aaacttgaga
     9961 taccatattc ttctgtttca ggaatatgat tttgatagcc aagctctaac tctttgaacc
    10021 agcccactga ataggaagtc tcatctatat taaaaagatt tgtatttaga attttcgata
    10081 agtctacttc acctttaatt gtcctaatta ttttggcatt ggactgtaac ttagcaatta
    10141 gaccgttaat tttgtaaatc gtcttggttg acactaagtc actattattt aaaagtaata
    10201 tgttacaaca ctcgaattga tcaattaaca agccacgaat atcctgttct tcttcaacta
    10261 cattaccttc agcttttctt tcctgaatct tttcacccgt ttcgaaatta tcccaaaaac
    10321 gttttacatc cactactata ataatggcac caatctctaa tcgttgggtc aaatcaatgt
    10381 ctaaagggtt tttagctaat ataattgctt gaataattgg aattggtttg ctgattcctg
    10441 aagcttcaat aacaatttga ttcaagtcag aaaattgcac taattgatct agttcaacaa
    10501 tcaaatcttc gcgtaatgta caacaaatgc atccattcgg catcgaaaca agtttttctc
    10561 cagttctttt aaaacctttc ttgtcgacta ataccccatc aacatttact tcccctatgt
    10621 catttacaat gacagcaatt ttctttccgt gatcaccgta cagaatatga tttagaagta
    10681 tcgtttttcc tgaaccaaga tagccagtta agattgtaat aggtattttt ttcataggga
    10741 acctctttct ataccttgaa tttacacttt aagtgcaaca cataaaaatg agtcataatc
    10801 gatatccaac tagtataagt ttgtcgagaa cactcctaga aggaaaataa ttatgagcca
    10861 gtatcgtcat cttactatac tcgaacgaga aagaatcttt ctgcttcacg aagaaggatt
    10921 ttctattagt ataattggca acgacattca gcatagcccg tttactattt tacatgaact
    10981 gagaagaaac aagaaaaaaa ctattcacct tccaaagcgg aaaaaaatta tgcttatcga
    11041 agaaaaaaat gcggacgtta tcacattcta aatgatccgt gagtttggtc aattgttcgt
    11101 catttatttg tcgattttca gtggtcgcca gaggaaatct cgaatcgttt gaagcatgaa
    11161 catatggact tttcaattag ttttatcacg atctaacgtg caatttgcaa tgatcttttc
    11221 gatacagaac ccctctcaca cggcaataaa ggcctgatcc gttcattgca ccatcgagga
    11281 aaaacaagac atacaaaaaa tcatgtcgag tctcgtggaa agatttgcct tactcattcg
    11341 atccatggcc gtccaaaatc cgcagatgat agaagtgatt ttggtcattg gaaagccgat
    11401 attgtagctg gcaaaactgg tggtacttgt ttagtgactt tgacagacag aaaatcatgc
    11461 ttccttttag caggaaagaa ggtccccaga aagaaagccg cttatgtgag cgagaaaatg
    11521 attgaacttt taagcagtat tccaaatgag gcggtcaaaa cgatcactcc agatagagga
    11581 aaagaattct ccaatcattt cgcagttaca gaagcattga ataatatgcc cttttatttt
    11641 ccagatcctc atgcccttgg caacaatgaa caaattaaaa tacgaataga ctcattcgag
    11701 aatacttgcc aaaatcgaaa gagatagcta cggtagataa ctcaacgata aatcagatga
    11761 ttgaaaaact gaataacaga cctagaaagt gtttagattg gagaacacct tatgaagtct
    11821 tctttgataa agtgttgcgc ttgatttgac aattcaagac ataataaaaa gcagatcaaa
    11881 tccaaataag ggaaaaatga tctactctgg tattatcaat taattggcca agctattatg
    11941 ccgttttgct aaacgtctac ttcttccagt attgaccttg ataaaacaac aatcaggatc
    12001 ccgttttaat actctatgaa ctgtgtcaat actaacatgt aaagttgcag caatatcagc
    12061 taatgtactc ccatttaatc tcatttgctt tgcaaatcga taacgccgat aagcatcaat
    12121 attcttggaa tccatagaca ataatacttt tcttaccatg tatttcctcc aaaaattgaa
    12181 ttttaatgag ccatcatttc ttgagcaatt tcatgtttag acaatgaagc tggatagaaa
    12241 gtaggccaat tatgcaattc attatagagt ttttcttgac tttctccacc aaagaaaata
    12301 tggaaatgct ctgccttact tggtgcaatt ccatgatcac taaattgaat atatttaaaa
    12361 cgaccagcac ctgcatcatc agtttcaaaa ttaaaacgaa caccacggtt tcctttttca
    12421 taattcaaaa ttttgtatcc aacatatttg tatgtgtatt gatgatgttc accgttgact
    12481 acaaaatcaa tggtgttgtc tttaatgttg atagtatcaa tatctgtctt atagccagta
    12541 gtataataat ctttgtactc ggcagctgtc atgtctttat tgatttttgc tttgtaatcg
    12601 aaaacttcat ccaaaattcc atcttttaac aacggataaa cagattgcca ttcgcctgta
    12661 taatcactca attcgcgatc cttcacatcg gcatctttaa agtacccatt agcaactgtc
    12721 ttttcatcct tcgcttcttt ttctggaact acctcttcac cagcaaccat agttgttttt
    12781 tctaacgctt ttagattgtc ttccattact gaaacataat cttcaccatt atccatttgt
    12841 tcttttgtaa gactttcaag aggattcagt acttccaatt ttatcccagc ttcgttggcc
    12901 aaagtttttg caattttatc attagcattc ttttcaaagt aaatataatt gatcttattt
    12961 tttttaacat actcttttaa ttcagctaat cgaccagaag atggctcttc ttcaggactt
    13021 agtccagcaa taggaacttg tttcaatcca taatccaaag ctaaatatcc aaaggctgcg
    13081 tgttgcgtca caaaactttt ttgtttcgct tctttaagac tagtggtata gtcagcatcc
    13141 aaccgtttca gtttagtcaa atacttttca gcatttgtct caaatacttt tgcttttttc
    13201 ggatacaatt taactaactg atccttgata tttgaaactt ccttaattgc cattttgggt
    13261 gaaacccacg tatgaggatc tagttcatga tggtgatctt cttctccgtg atcatgatct
    13321 tcttcttcac tacctggcaa taaaatcatg tcttttgttc cttctactac attaggccca
    13381 gctttcttcc aactttcttt agcttttggt acccatgatt ccatgttttc gttatgatat
    13441 acaaaaacat cagcatcatg agcttttgcc atatccttag ctgagggctc atagtcatga
    13501 ggttctgatc ccgctggaac cattaaatcc acgttcgctt catcgccgac gatgtttttg
    13561 gtgaaatcat acattggata gaatgttgtt acaatttcta attttccatc tttatcattc
    13621 gatacttttg catcattagt gctggagcaa gctcccaata atcctagagc tgctatccca
    13681 ataagtccta cactgatttt cttcattctt tttccttcct taattatgct aatttcttca
    13741 ttttatttcg tttatgttct ttgataattt ttaatgccct ttttctagtt ttaatattcg
    13801 ggcttttaag tcgtcgatat gcactagata tatccgtttt ctccattaga aattaccccc
    13861 aatcactact tatcattatt tgctttccgc cagtaattta tcaaaactct gtttgatcct
    13921 ttcttcatcc aacatttttc cgattagaat aatagtggtt tggtcttttt gtcgagtggt
    13981 gtattgaaaa ttaacctgtt cgtttacctc ttgcatggca actataaaat cctgctcttg
    14041 taaagcaatc aatcctttaa aacgatacag gctcccttgg ttggttaaaa tcagccagtc
    14101 aatccattgg agtaaaaaat ctttttttat gtcttgatct gaagttaaga gaattgattt
    14161 aaactcatgt acttgatggt gttgatgata gtatttgcca ttatagtgat tttctgatga
    14221 atcactttca aaaactaagg gatgattaaa ttttttcaaa ttataaaaat cctttttttg
    14281 aatcgtttca ctatgtgtga acattcgaat atcggataaa gggttaatac ttttgatttc
    14341 tctctgtaat ttttttagtg cagataaatt caagttttgt tttctagaca caaaaatgcg
    14401 atctgccatg acaagttgct taagggcttg tggttctctt tcaataagtt caaaactgtc
    14461 actatcaata acagtcaata aactatcgat atatactctt cctcttagtt gaggcgctgt
    14521 taaaagtgtt tgaatgattg gttggggatc tgctatacct gtagtttcaa tgatgatttg
    14581 tgaaattggt tgttgatgtt cttctattgt ttccagtaaa gaaatcaata ttgctaataa
    14641 atcactgcga agactgcaac acatacatcc attatttagt tgtaacaccc gttcctcgct
    14701 atgaactaat aatttgtgat caatcccaac ttcaccaaac tcattttcaa ttataataat
    14761 ttcttccctg gggtagggtg agacttgcaa ggcttgattg attagcgttg tttttccagc
    14821 ccctaaaaac ccagaaacga ttgtaactgg tatgcccatt ttgtcacctt tttaccactt
    14881 agctatttca cttctttaaa aattgcccgt ctgcgcaatt ttggcgaata cttttttaat
    14941 tctaaccgtt cagggttatt ccgtttattt ttgctggtga gatacagacg ttctccagtt
    15001 tcgacacatt ccaaaataat attttgacgc ataaatcttc ctccttcaat acttatcgat
    15061 cttcaagata tgcttgaatt tgttgtgcat cttcaaaagt taactcgcca gattccaatt
    15121 gtgaaactaa attttctttc atatcaacag gtatctccca ataaccatcg atacattgaa
    15181 ataactcctc gtcatactct tcaaaaattg gatagattct taaaaaatca tcaaatgata
    15241 agccttggtc ctcatagtaa tctttgacta atccattttc aattgcctgt tgggtcggta
    15301 aacccgtttc agtaataatt cctctctcta ccatcgaacg ataaaaagtg catttatcta
    15361 gcgattgctg ggtcgtttca agataatact ttaatccttc ttcaactaaa ggtgggtaaa
    15421 taatttccat tttgattccc tcctaaaagt tatatattaa actattttga agctccttta
    15481 attactttct ttccattata gtaccctttt aaagatacat gatggctacg tctataatca
    15541 ccattcgctt cgtcaaatga aatttctggt tttactacag tttgatgagt tcttcttaac
    15601 cgtttcttcg ccttagatgt ttttcttgct ggtactgcca tgatatttcc tccttttacc
    15661 aacttgcttt ttttactcca ggaatcaacc cttgatgggc aagttctcta aacttaatac
    15721 gggacatacc gaactttcgc atataccctc ttggacgacc atccgtctga tcacgaagcc
    15781 tcagacgatt cggatttgaa tctcttggca atttagcgag agcggtgcga tctcctgcgg
    15841 cttttaattc ctgacgttta tctgcatact tttcaatcat cgccatttgt ttctttgctt
    15901 tagcaatttt cgactttttt gccatatacc tttatactcc ttttattttg atttagacac
    15961 ctcaaatcgt aatcgttacg ttttgacact gatactttac caacaagagt tgctcttgtc
    16021 aacaataaat aacatgaaat aaaactcata tgaatagata actatttgaa aacgaattta
    16081 tcggtacata gagataatca aatcatttaa aagaatatgc agtttaggct ctgaaaaata
    16141 agaattcact tttattagtc caatcaaaca caaataccgt tttaagtagc ttttcctcta
    16201 cttaaaacgg caatatgaaa gaaactataa ctttttattc aatcttttat gtttaactgg
    16261 tttatcgcca attttttaaa actttgatta ttccttatat tataagaata gacattaagt
    16321 gaactaattc aatcatactg attctttcgt gtattcaaaa ttagatgctg tttaataaaa
    16381 ttattctttt tgaaaaagaa ttataactat atcccaaaaa ttgtaggtta atttaaagcc
    16441 tatttcatca tcgtgattga gcttcttttt catagacgaa tttctcagat agtttagttt
    16501 tctttatgag atttttgtat atttctgacc ttcgatacaa ctcattatga gtaccttgat
    16561 caactagttt tccttgatcc atcactacaa ttttatttac cttttcaata gacttcaagc
    16621 gatgcgatat aattagtact gtcttatctt gtattaaacg atttaaactt tcctgaatac
    16681 gtttttcatt ttccgcatct aaactggcag taatttcatc taaaattaaa attggcgcat
    16741 ttttcaaaaa agcccgtgct atggataggc gttgtcgctc tcctccagaa agtgaacttc
    16801 cgttttctcc gaccaatgta tgataaccgt caggtagttt ttcaataaag tcttcgcagt
    16861 tagctaaacg agctgctttt ttcacttcct catctgacgc ttgactattt ccaatacgta
    16921 tattttccaa aatacttgta ttaaacaaag ttacctcttg aaaaacaata gcgattttgc
    16981 taaacaaaga agctggagat acacgtttaa tatcataccc atcaattaaa atacagcctt
    17041 catcataatc atacagtcta gacactaatt tcaagatact agttttcccg gaaccactag
    17101 cacctactaa cgcagtcact tctccttgtt tagccgtaaa agagatatga tctaaaattg
    17161 gggtattgtt atcatatgag aaagagacat ctcgcaactc aatgtcaaaa gatttcagag
    17221 gactatctga tccctcttgg atactggttt ccttcatagc tctaattcgc tgtattttag
    17281 gagctaaata aaatatttca agcactgctt ctttcataga atcgaaggaa tcctttattt
    17341 ttattgcggc tagtaagtaa ccaacgacgt agagtatagt cacttcaccc gttaacagta
    17401 agtgaacacc tactagaatg actactgcta aactaacata tgagaaaata gaggataagg
    17461 ccatgactga aaaagtactt aattctacct ttaaatgaat cctttcactc tcttccattt
    17521 ttttgaaaag tctgtcttga acttttttag atagattaaa gctattaatc tcttgctgca
    17581 attctatagt ttcttgaaat tcttccgagt tctctctcaa agtatcgtaa tatttagtat
    17641 tggctttcgt ttgggatttc tttgataaca agattaagac aaaactaaat aacgttggca
    17701 aaataacagc taatcccatt ttgacattac caaccaaaag catcactgaa ataaaaggga
    17761 aaaacagagc cataccgccg gctttaggta ttgcatgact catcgcatgc tcaatacctt
    17821 caacgtcaga catgatagtt tgagataaat ctgataaatt atgttttgaa aaataggata
    17881 atggtaaatt tgacaaatcg tctgcaattt gcactcttaa atgcgcactt tctttataag
    17941 tactattata taagttttca tactccctat ctaacaacca atacatgaaa agcaaagtaa
    18001 caaacgatac ggcaaaataa agccaacggg gctttgtatt ttctaaaact aattcgtcta
    18061 tcagcatcat tataatgaat gctggtacca tattaatgca gtatacaaaa aaactagaaa
    18121 tagaagcttt agttaaagct tctgcgccct gatcacttaa agcaaatttg tttttataaa
    18181 aacttttcat tgtcaagcct ccaatcattt gcattctcat aattagtgac caattgttta
    18241 tacacttgat gtttagccat taattcatta tgatttccac gttctactat tttcccttct
    18301 gacaagacaa gaatttcatc tacagattta atgctggata atcgatgagc tatcataata
    18361 actgtttttt ctttcatcag atgttgaaaa gccttttgta gttcatactc attatctgga
    18421 tcaatagatg cactggcttc atccataata acaatctttg catcttttaa aattgctctg
    18481 gcaatagcta tacgttgttt ttctcctcct gacagataaa ctcctttact accaattaag
    18541 gtatgctctc tttcgggaaa tttttctaaa atcgattcgc aaccggctaa tcttagcgcg
    18601 tcaaatactt tacttgctgg cgcttgagga tttgctatag aaacgttatc gtaaatactc
    18661 tgattgaata gtttcgtatc ttgaaagaca aaagcaattg tgttaataat tgtgtctttt
    18721 gaatagtgat ttaaaggctt accaccaatt ttaatctgtc ccttatccac attgtagaaa
    18781 cctgaaatta gtttagctat cgtactcttt ccgcttcctg attttcctac taatgcataa
    18841 attctttttt gttctaaaac taagttgaaa ttttctaaaa cacactcttc tttgtatgaa
    18901 aagctgacat tttcaaatgc aatgtcacaa tttttaatct gtgtctcgtt cccatatttt
    18961 agttggtctt gcttcatttc taaataaagg gagtctagtg tttcgactgc atatcttgct
    19021 tcaaacaagt gcatacttac atacattatt ctcatgaaag aaacaaaaat aattccactt
    19081 aaaaaaaaca acatcaacaa gtcaacagct aatatcttgg gagtggtaag agaagttata
    19141 aaaaaggtta taggaactat caaaatgcaa actatgccaa aaaatagcca ttgaaaaaga
    19201 acaaaaggtg ttttcccact caaagaatac ttatatgcaa acttagcata atcgttaatt
    19261 gctttattca aggctttaaa tgatgttact ttagcaccaa atatctttat aacttgaatt
    19321 ccgcggatat attctaccgt ttcagagctt aacacatcta acgattcttg atatttttga
    19381 ataaaatttg tattctctgt cattttcttt aacaagaata caccaattac taacatggcg
    19441 attagaacca atccaatttt aaagttaatg aaaaagccta aggcaactga taaaacaggt
    19501 gttactatgg cttgagcact atctggaatc aagtgagcaa ttgccatatg tgttttagcc
    19561 gcgttgtcat caattgtctt tcgaatatat cccgaagaat ttaaatcaaa aaaacgaaaa
    19621 cttgcttctg ttaaaccgct aattcccttt tttctcaaat tagtctctaa gcgaaaccca
    19681 aggatatgag aaaataagcc agaaaaaata taaaataaag ctcctaaagt taaccaagca
    19741 acagtttgaa ccgcataact cttagctaaa tattcatctc ctacaataat tagagactga
    19801 agaaatttgt aaatactgta atatccatag actgttaata cgacagaaaa atcagaaaat
    19861 aaagtggcta accatccgta gtatttcatt ttagggacat aactaaataa ttttttgtat
    19921 actttcattt tttcctcccc cgcattcaat ttcttctctt attcgtttac aactgttaat
    19981 gctttccgta atagcgtaaa ttagagatgt acaaacagat aaaaggtaaa ctacgttcta
    20041 ttttttgtat ttttttaaga cttttcttcc aatcaataca ccaatcatag ataaacttgc
    20101 tacaactaac actgaaatga ttccccatat acctaccgca tagtggatca ttgcatccat
    20161 tgttgcagca gattgtcctt tatctatcca atcttgacga aaacgatctg taaagaacca
    20221 tataggaatc cactgtccgg cagcactgcc taattgcatt agagcccaag acgcaacttg
    20281 aggaattgct cgatcatatc caaatacaga tagaataata tcagctaaga tcgccatact
    20341 aatcgaactg ataaaccaag gtaagtacgc cccgcccatt aacgtaaaaa ataacaataa
    20401 aacaattgtg taaatagtaa aaattccttt tctagggtag ttatagctaa tataaacaaa
    20461 tatgattcca gataataatc caaaaatccc gggggatatg ctgtgaccaa acgccccacc
    20521 aatactacta accattattg aaaaaaagta aattactagg gaaataactg tagctaaacc
    20581 aataaaaata taatcttttg ttttcatata tattctcctc aattctattt cgttatgtca
    20641 ttaaaaatct gttctatcaa agttgaatct tctactctaa gttttatatc tttttttatt
    20701 ccaccatttt ttaaataaat aattctattg catgttttat aaagaaattc cggatcatga
    20761 gtagctataa ctactgcacc cttttctttt aagtctttaa taaggtcagc aatcctttcc
    20821 atattaatat aatccaaccc acttgtaggt tcatcaaata gaaataaatt agtttttgac
    20881 aatgaagcta tagaaaccaa taatctttgt ttttctccac cggataaatc aaacggtaat
    20941 tgatctttca ttttataaag ttccattttt tttaaaattt tttcttgctg atctttacta
    21001 actatttcat tccccagggc taactcgctc ctcactgatt ctgtgaaaaa ttggtaatcc
    21061 atttcttgca ttactaaaaa cggcgatgac aaattttttt tattttcgat tatctttcct
    21121 ttggtagggc gaataatctt catgagtatt cttagtaagg ttgttttccc cacaccgttt
    21181 ttccctacca aaccaataac atctccaact ttgacatcaa aatttatgtc ttttagaata
    21241 ttttcataag taatttcttc aacttttaat acatctgcac ttaccttttc gatataggga
    21301 acttcaatcg aactattaaa aatgtcaaat ttccttaatg cgttattgtt ttcagttttt
//
LOCUS       DAFLWC010000053        21241 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.054, whole genome shotgun sequence.
ACCESSION   DAFLWC010000053 DAFLWC010000000
VERSION     DAFLWC010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21241
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.054"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(48..659)
                     /locus_tag="L1V17_001770"
     CDS             complement(48..659)
                     /locus_tag="L1V17_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBN1236537.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(782..907)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(989..1705)
                     /locus_tag="L1V17_001771"
     CDS             complement(989..1705)
                     /locus_tag="L1V17_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBN1236538.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(1711..2280)
                     /gene="scpB"
                     /locus_tag="L1V17_001772"
     CDS             complement(1711..2280)
                     /gene="scpB"
                     /locus_tag="L1V17_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBN1236539.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(2264..3061)
                     /locus_tag="L1V17_001773"
     CDS             complement(2264..3061)
                     /locus_tag="L1V17_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBN1236540.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(3031..3402)
                     /locus_tag="L1V17_001774"
     CDS             complement(3031..3402)
                     /locus_tag="L1V17_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBN1236541.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(3421..4308)
                     /gene="xerD"
                     /locus_tag="L1V17_001775"
     CDS             complement(3421..4308)
                     /gene="xerD"
                     /locus_tag="L1V17_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HBN1236542.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(4404..4877)
                     /locus_tag="L1V17_001776"
     CDS             complement(4404..4877)
                     /locus_tag="L1V17_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBN1236543.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(4982..5845)
                     /locus_tag="L1V17_001777"
     CDS             complement(4982..5845)
                     /locus_tag="L1V17_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBN1236544.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(6041..8140)
                     /locus_tag="L1V17_001778"
     CDS             complement(6041..8140)
                     /locus_tag="L1V17_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBN1236545.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(8360..9469)
                     /gene="rpoD"
                     /locus_tag="L1V17_001779"
     CDS             complement(8360..9469)
                     /gene="rpoD"
                     /locus_tag="L1V17_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBN1236546.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(9493..11334)
                     /locus_tag="L1V17_001780"
     CDS             complement(9493..11334)
                     /locus_tag="L1V17_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBN1236547.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(11516..13831)
                     /locus_tag="L1V17_001781"
     CDS             complement(11516..13831)
                     /locus_tag="L1V17_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBN1236548.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(14016..14876)
                     /locus_tag="L1V17_001782"
     CDS             complement(14016..14876)
                     /locus_tag="L1V17_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HBN1236549.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(14935..15456)
                     /locus_tag="L1V17_001783"
     CDS             complement(14935..15456)
                     /locus_tag="L1V17_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HBN1236550.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            15734..16495
                     /locus_tag="L1V17_001784"
     CDS             15734..16495
                     /locus_tag="L1V17_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1236551.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            16521..19112
                     /gene="mprF"
                     /locus_tag="L1V17_001785"
     CDS             16521..19112
                     /gene="mprF"
                     /locus_tag="L1V17_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBN1236552.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(19300..20487)
                     /gene="tuf"
                     /locus_tag="L1V17_001786"
     CDS             complement(19300..20487)
                     /gene="tuf"
                     /locus_tag="L1V17_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBN1236553.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            20855..21211
                     /locus_tag="L1V17_001787"
     CDS             20855..21211
                     /locus_tag="L1V17_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBN1236554.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
BASE COUNT         5817 a         4457 c         3720 g         7247 t
ORIGIN      
        1 ttttttccaa aaaaaaagac caagaaattt cttgatcttt ttgatattta tttgactgct
       61 gtatgacgtt gttcgaactg atgttgtttt cgacttaacc atggaagaag ttgcgcatgc
      121 agcactaaaa agacagcact cacgatgaat cctttgatca agttgaaagg aacgatccca
      181 atcagtacat agtttgctaa agacatgccc agcatctgtg ttgcgttcag ccctaaaaac
      241 attaagtaaa gaggcgtaat aacgaaataa tttgcgatac tcataaaaat agttagagcg
      301 atggttcctg taatgacacc taaaaatttg tttcttcctt tatgctgttt ctttacacta
      361 aagaaataat aaatcgggaa tgtaaagatc gttgttgata agaaactagc agtgtctcct
      421 accaaattat ccggagaaaa acctgtagtc agcagatgta atactgaacg caagaacgct
      481 gttgcaactc cggccgctgg accgaataag aacatgctga tcaataccga gatatcacta
      541 aaatcgatct tcaaaaaact aaaagccggc atgatcggaa aagcaaaata ctgtaaaact
      601 aatgcgatcg cagcaaacat cgctactgca accattttct gtacacgggt gttcttcatt
      661 tgaaatcctc ctgttaggac tcctcttcag cgaacttttt gacgtttctc tccaaatgaa
      721 aaaactctat tttccaggga aaatagagtt agagttattt gatcaagcgt cgtcaaataa
      781 gctctatctt ctttatccag actatactgt cggtatcgga atttcaccga ttcagctatt
      841 tttttgcaaa ataggtcgtg gactataacc accggtcggg aatttcaccc tgcccctgaa
      901 gacgaacctt atataatttt tgtttacata ttcattatac atatctattc aaaaaacgca
      961 acatctaaca cttataaaaa gtaagtgttc attttgagtg gttcagcaaa ctgctgactt
     1021 cttttttgtt cagttcacgg taatccccag gacgtaggcc ttgtaaagtc agatctccgt
     1081 atttttcacg ttttagtttt tgcacaggaa gaccaactgc ttgaagcata tttttcactt
     1141 gatgattacg tccttcgtgg atcgtcaatt ccacgatact gtggtttgtc ttaggatcca
     1201 ctgataaaat ttggaattta gctggagatg tttttcgtcc ttcgatcttt attccttttg
     1261 tcaaaggtgc aagcatcgat tttgtagcga tcccttttac ctttgcaacg taaactttat
     1321 ccacttcatg ttttggatgt gtcaggcgct gagcaaaatc tccatcattt gtcagtagca
     1381 agatccccga agtatcgtaa tccagtcgac ctacaggata gatacgttct tttaccatcg
     1441 gcaaaagatc cgtaacaact tttcttcctt tgtcatctgc aacagcagaa ataactcctt
     1501 taggtttgta caataaatag taaccgtatt cttcttgata aattgggact tcatccactt
     1561 ccacagtgtc atgtttccca acttttatcc ctaattccct tacaacttgt ccgtttactt
     1621 ttacacgtcc tgcaaggatg aattcttctg cttttcgacg agaagtgatg ccagcgtggg
     1681 caattacttt ctgcaatctc tccattacaa ttattctcct ttattcattc catcaaagaa
     1741 tagatctggt gacacgtctt cttcaagtga aatttccatt tcttgtgtat caggcagttc
     1801 ttctaatgat ttcaaaccaa aataatctaa gaagtagcca gttgttccat ataatatcgg
     1861 ccgacctggt ccttctactc tacctttttc ttcaatcagt ttatgggcag ctagacgctg
     1921 taccgctcct gaaacctgaa ctcctcgaat ctgctcgatt tcagctcttg tgattggctg
     1981 tttataagcg atgattgcta aggtttcgac ggcggcttga gataatgtgt ttgatgtccc
     2041 ttgcgcatat cgcttaagta agggagccag ctctttttta gtcgttaata cataatggct
     2101 ttccgtttca aaaatatgca aagctgagtg cgagttttga gtgtaagatt cttttaattc
     2161 tttcactaaa cttgtgactt ctgcttcgct gagatttaac agtccgctta attcttcatt
     2221 actgatccct tcctcgccaa caataaaaag aagggcttca agttcactta atttcgtcat
     2281 gttcggtatc tcctactgct ggataaagca taattgattc atagttttct ttttgttgcg
     2341 caatgatctg cccttttttc atcaattcta gcaaagccat aaaagtagtg acaacttcac
     2401 ttttagaagg tgactcaaaa aaagaatcga aagtacagcc atgcgcattt ctttttatac
     2461 gctcttcgat aaataccatt cgttcttcga tcgttgtgtc atcgggcgtg atcgtttttt
     2521 ccactttttg agaaaatttc ttacgttcta agattttctg catggcacgg atcaaatcga
     2581 tttttttgac ttgtcctcgc ttcaacggct tttcagcatc cgctaaccca tcgatgttca
     2641 taggttcttt tgtgtaataa agacttcgtt cctctgcttt ttctgtcagt ctttcagctg
     2701 catatttata tttacggtat tctaaaagct gagtgaccaa ttcttctcga ggatcttctt
     2761 cccataattc ttcatcgtct gtgacgaatt cttggacagg aagcaatgtc ttgcttttga
     2821 ttgccatcaa tgtagcagcc atcactaagt attctcctgc aacagctagc tcgagtgttt
     2881 tcattgtatg gatataattc atatattgct ccgtgatcgt agcgatcggt atatcatata
     2941 tatcgatttc catttgctga atcagatgaa gcagcagatc gagaggaccc tcgaatacat
     3001 ctaatttaat attgatctcc gtcaactcat tcactctttc ttctttttct ttgctagcca
     3061 ttttccaatg taaggctctg tgatttcagt tgcacggatg gagacatccg ggtacttttc
     3121 ctgtaattca tctaacattt gaaagcccat attctcaccg cgataagacg gattcaaaga
     3181 aatgtcatgg atgatcagct gatcgttcgt tgcccagtaa ataccaataa tcccttgaat
     3241 gttggttgaa ccttctggcg taaagaaaaa aagttcataa tcgtcttcag attcgtacgt
     3301 atcaatctcc ttcaacaaag aagttttacc tgtcagtttc ttatggaaac tcaatagtcc
     3361 catagcaatt ttacggtttt ctttccggta atgtgttaac atcttctcac cttcctatga
     3421 ctaagccctt ggaaaatgct gcttataaac atccgtcatt cttttcttcg tgatatgtgt
     3481 ataaatctga gtcgtagaga tatccgcgtg acctaacaat tcctgtactg tccgcaaatc
     3541 agctccattt tctagcagat gtgtggcaaa gctatgccgc agcgtatgtg gtgttacttc
     3601 tttgtaaatc ccagcctctc gtactaactg cttcagattt ttccagattc cttgccgaga
     3661 aagacctttc ccatgattat tgacaaatac atgcatttca gatgcgtcct ttacaagtaa
     3721 tggacgtgct tcgtctaagt agcgttccag ccattggatc gcataatcac ctaaaggaat
     3781 gatccgctct ttatctcctt ttccaactgt ctgtaccagt ccaagagaaa gatgaagatc
     3841 tcccaatttc aatccaatca attcactgac gcgcatccca gtagcataca tgacttccaa
     3901 gattgcacga tctcttatcc ctaacgtttt tgtcgtatca ggtgcttcaa tcagcttttc
     3961 tacttctgtc agagtcaatg tacttggtaa tttctgtgct ttcttcggcg tatcgatatg
     4021 ttgcatcgga tcatgatcag tgatacgctc ttgccgtaaa aactgatgga atcttctgag
     4081 acttgagatc atccgagtaa cagttgctgt cgcttttttt tcttcatgca acttctccag
     4141 aaaacggatg actaaaaagc gatcgacatc ctgccatgaa gcaattttct gctcctgtag
     4201 aaaatgcaag tactgttcca aatcacgttc atagctttgt cgtgtattgg cggacaatcc
     4261 ccgttcaata ttcaagtagt ggagataatc gttgatttgc tctttcataa taatccccct
     4321 catgcctctc tatcatatca gataccgctt cattctgata gtctttttcc ataatctgag
     4381 caaagaaaaa gccgtctaga cactcagacg gactggtttc ttttttcttt ttcatagcat
     4441 tcctgacaga ttccatggaa cgttagccga tgatctttta ctaaaaaatg ataacgttct
     4501 tctactactt gctccacttc aagtaaaaga tcctcttcta cttcctcgat cgtgccgcag
     4561 ttcaagcata gtaaatgatg atggaaatgt ttggcgcctt cttttctcaa atcataacgg
     4621 gctaatccat cattaaaact tactttatcg acaattttca attctgtcaa gatttcaagg
     4681 gttcgataaa cagtagcaag tccaatttcc ggactctttt ttttcactaa aaagaagatt
     4741 tcttctgcag ataaatgctc tttctcattt tccaaaagca caagcagagt agcttctctt
     4801 tgcggtgtca gcttaaaccc cgcttcatgt agctgctgtt ttgttttttt catcgccgaa
     4861 atagcattca tgaccattta ctcaacccca ataatttata ataattacaa ataaaaaaag
     4921 atataacact atgttaatta aaattattat aagctagtta agaaaaacat gcaagggatt
     4981 ctcaattaga ttttttgact agttttgtca caccgttttc ttgtgtaatc aatccttgtt
     5041 tcaaaagatt acctaatgcg cgcttaaatg ctcctttgct gataccaaaa gctttcatga
     5101 tttcttctgg atccgattta tctgtaaagt tgatttgctg atctgcagaa cgttctaaaa
     5161 tggttaaaat catttgtgca tcatctgata tagcttcata tgctcttggc ttcaatgaaa
     5221 gattcagtac accgtctggt cggacaccaa tcactcgacc ttttatctgc tcgcctagac
     5281 gaggttcatt atatcgttca gaaggatgga taaacccaag atagaaatct tccgttaaaa
     5341 cgtacgtacc tgttaatttc aagcggtatg ctgttcctat cacatctttg tttttcattt
     5401 cttctgttcc atatttgctt aaagatttga atattttttc atctgctaaa ctgccccaaa
     5461 tacggtcttt tgcatcaact ctaagggaaa tcatcaagcg atcccctttt ttaggccata
     5521 gctctgtcat tgtcggcaat tcatcaagag atacgacaaa gtctttatct ggaagaccga
     5581 tatcgacaaa cgcacctaaa tcttttcgtg tagcagtaac gattccaaaa gcgtaatgac
     5641 cgatacggct tttaggaatt tgtgtagtga tccgattttc atgtttttga ttttggtaac
     5701 cgaatccttc aactgcttca ccgattttgt gttcaccttc tgatttgctt aagccaaagg
     5761 tttgtccgtt tttttggaca aagtagtttt tttcattttc atcaataata atacctgtaa
     5821 atatagttgc taataaatcg ttcatttttt tctccctcta tagtgaaagg ttttcttaat
     5881 acatttcttt gctatcataa cataatgtta tctacttgaa tagctgagcc ttggtttgga
     5941 aaggtgaaaa aaggagtatg acaacagttg tgtcatactc ccctttttcg aataaacggt
     6001 gttaaacggc aggctcacag cctctttcat ttgcctaaaa ttaattgctc ccatttcctc
     6061 cgaaccatcc agttttacag ttgatggtta cgatgtaaaa tggcaaagca ctttctccaa
     6121 tgcctttcat caatgcagat tttgttgaag tggcatatag attataatag ccttccccat
     6181 tttcgattct ggctttttct aatctgtaac ctccttcaac gatatatcca cgttggatac
     6241 atgtagcaat cactttgctt tggacacctg gtgcccacgt ccatgctgga ttagatgcat
     6301 cggcaatatc acttgctctg gcagatttga ttggctgatt cgctgagttt gaagaggaag
     6361 gggtcgagga tgccgcttct tgctgtgctg cttgtgcgac cgcagcttgt tgagcggctt
     6421 gagctgcagc tgctgcttga gcggcttgtt ttgcttgttc ttcagctgct tttttcgctt
     6481 cttctgcttt tttcttttcc tcttcttctt ttttctcttt atcagtgagc atcttatcta
     6541 cttgtttcaa ttgttcattc aactgagcag atagatctgt atttttcact ttttctactg
     6601 cttcttttgc cgtcttgtat tggtcgcgtg ttgctgaatc cactactttt ccgtctttaa
     6661 agactatagc tgttttttct ttagctgttt gcaattcagc atattgattt ttagcttctg
     6721 tttgtgcttg ttgaatcaat tttccaaaat ctgtgttatc cgtttcgatt gcttggatct
     6781 ctttatctgc tttcaacttg atgtcatctg ctagatgatc atcgacgatg gcaggtgcta
     6841 tgaaccactc attcactttt tggatatctc ggatcttaga ttggatatct tggtaagttg
     6901 tttctaactc tgaatatcct ttttcattct taagactgga taaatcattt tttagttttg
     6961 ataaatcttg atgaatcata tctgcacgaa taaattgatg gtgatcatct gtataaaagg
     7021 cagcaagttt ctcatgaagt tcttccattt gttgctgtct ttttgcttct gctgctactt
     7081 cggcttctac tttttgatga tggtcataat aagcccagct tcctccaccg agtagaagta
     7141 ctgctgctaa aacgagataa ggtacttttt ttgatttttt cttttgcgct ttatctggat
     7201 ctgttttttc taagtttgat tcttgatgtg ttttttcagt atctggcacg attgttattg
     7261 atttcgcttc tgcttcaaac agcttaggct ggttctcttc tttttctatt tttgcttcaa
     7321 gatcagtacc ctctttgctt acagattgat tttcagcatc ggattcacta tttatttcat
     7381 cgggctctgt tgactttttg tctgtgtttt cgagtatttc ttttttctct gcttccggca
     7441 gtttattcgt tttttccttt tctaattgtt tttcagtaaa tacttcagtt ttttctgtga
     7501 tatccgtttt tacgtctttt atttttactg tttctttacc tgtggcgttt tctctatcag
     7561 agtctttttc agtttcttgt tccttttctg gctctacttt gttttcctgt gcaatttttt
     7621 cactgatcat tttgagcagc tctttcgcgt gctcttcttt tgtatcttca cgatgtgctt
     7681 tgatataagc ggatagtatc gaattttctt cctcattatc gacgatttct ttcagttcag
     7741 ctactcttct tttttgtttt gattcaagcg tttcttcttg attctttcct gattcttccg
     7801 aagtctcatg aacagttgct ttcttctgtt catttttctc tatattagtt acttgatcgt
     7861 gagcaggtgg ttcttcgtct tctggttctg ctttttcgaa taattccatt acagattcta
     7921 gaggtaaatc tttcaattcc gaccattcga ttggatcgtt taattctgta tcaggaaaga
     7981 ctgcatcttc agttgattta tcctgcatag ctgcatctgt atttgtttct tcaattgatt
     8041 cttttatttg ctgatcttct gcagttattt gatgaccgca gtctggacag atagtattct
     8101 gctccatttt tttcgatccg caatttggac attttttcat cacttagcga tcggctcctt
     8161 tactaggttt acgctaccat ttaatctatc atattctata cgtcacgcca atagcttatt
     8221 tttaggattt acttaaaaat aatgaatgaa tttccttcct atagaaaaaa aagcttgaga
     8281 ctgcgtagtc tcaagctttt tttcttttaa aataaaccaa acagttttac tgatttctct
     8341 tctggtcaat agtccacgct tattctaaga aatcttttaa ttgttttgaa cgagaaggat
     8401 ggcgcaattt tcttaatgct ttagcctcga tctgacgaat acgttcccga gtaacaccaa
     8461 atactttccc tacttcttcc aatgttctcg tccggccatc atctaaacca aaacgtaagc
     8521 gaaggacatt ctcttcccga tcagtcaatg tatctagtac atcttccaat tgttctttta
     8581 gtaactcata agctgcgtgt tctgctggac ttgttgcttc ctggtcttct atgaaatcac
     8641 ctaagtgaga gtcatcttct tcaccgattg gcgtttcaag ggaaacaggt tcttgcgcga
     8701 ttttcaagat ttctcggact ttttctgttg gaagatccat ttccgcaccg atttcttctg
     8761 gcgtaggttc tcttccaagg tcttgcagca attgacgttg gatacgtatc aatttattaa
     8821 ttgtttcaac catatgaact ggaatacgga tcgtacgtgc ttggtcagcg attgctcgag
     8881 tgatggcttg acgaatccac catgtagcat aggttgaaaa cttaaatcct ttgcggtagt
     8941 caaatttttc aactgccttc atcagtccca tgtttccttc ttggatcaag tcaaggaact
     9001 gcatgcctcg tcctacataa cgtttagcga tacttactac taaacgaagg tttgcttctg
     9061 ccagacgctg tttcgcttct tggtcgcctt cttcgatttt caatgctaac gctacttctt
     9121 cttccgcagt taaaagggag acacggccaa tttctttcag atacatacga accgggtcat
     9181 tgatttttac accggttggc gcagaaagat cttctgtttt tgcttgttca gcttttttct
     9241 cagcactctt caagctgtga attgatggat caccattttc atccaccaca ctgatacctg
     9301 cgtcttcaat cttttggatc aatttgtcca tttcatctgc attcaaagtg aatggtgtag
     9361 caagctgatt ggataaatca tcatatacaa cttgtcgttt gggtttgttt tctttgatga
     9421 aagctgctac tgctgcttca tacgtttttt tatctgttcc atttgccata aaagaaggcc
     9481 ccccttgagt agctatttgg cttgttttaa ctgtttcgtt aaattgatga tttcaatcgt
     9541 caattcaagc tcaagctgtt tgtttccagt tcgtctggct tcttgctgca tttgtttttt
     9601 taatgttatt tcatcagcta agccagattt gctgatcaca tctagcaagt cttggatttc
     9661 tcgtggcgaa ctttcttctg ccaccggtaa atattcgatt tccaccacca accgccttaa
     9721 attttcatct tgcaaaaagt ctaaaaactc tgcaaggttg aattcataat gttgtgagac
     9781 atatgcatcg aataaaaaat aaacttctgc atatgcatca tgaataaact gaaattctcg
     9841 ttcttttaaa atattacgga cagaaacttc tttaaatgca cgatataata gaatctgctc
     9901 tgccttttct acttgcgtca aaggtctctt tttccgtgca gtttcttgtc tcgtaacctg
     9961 agtgtgttga ctttcctgag gttcttgacg attttgctga tttgtccttc gaagatcgcg
    10021 cagttgtttt tgtatcgtct ctctgccgat ctgaaactct gttgacagtt gagatagata
    10081 catatcttgt tcgattggtg aaacaactcg gctaagttca actagtaatt cttcgaggta
    10141 ttcgatcttg tctttttcat tatctaaatt tttcccttgt tttaaataac gtgatttaaa
    10201 agtaaagact gtttcgcgcc catgagccac taattcttgg aaagatgctt ctccatactt
    10261 acggagatat tcatcaggat caagcttttc tggaacgact acgacagaaa gtgctaatcg
    10321 actgttttgc cgaagcaatt caatccctcg attggttgct tcaaaacctg cgttgtctcc
    10381 gtcatagcaa aagaccaatt ctttcgtcag cttttccatt tgttggatct gttgagctgt
    10441 tagacttgtc cccatagaag ctaatccagt tttgatacca gcctgccatg cagcaatcac
    10501 atccataaac ccttcgaaca acaaaatttc tccgtttttc cggatatcgc ttcttgcttt
    10561 atcaagatta aataaaactt gtcttttatt gaacagttct gtttctggac tattcaagta
    10621 tttgggctga tctttttcct gccctttttc aggtgcaagc cagcgtcctg aaaaaccgat
    10681 cgtctggcct tgagaattac gaagtggaaa catcactctt tgataaaaac gatcagacat
    10741 acggccatca tcatgcgtga caaacaatcc agagcgttct aacaattcat ttgaaattga
    10801 ttcattcttg aatacttgct gaagaaaaga acgctcatta ggtgcaaaac ctatgttgaa
    10861 ttcttcaatt aattctaaag acaacccacg actttgcaaa tattctaaag ctggctgtcc
    10921 agcttttgta tgcaatagca tgtgatgata gatttccgct gctttttcat gagcagcaat
    10981 cagtttcccc gtagcagatt caggattttg gacagctata gtacgctgac gccattgatc
    11041 ttctaacggt atctgttcga agtctgccac ttttaccact gcttctggaa aacttagacc
    11101 ttctagttct tgaagaaaag taaacacgtt tccgccttta ccacaaccaa agcaatgaaa
    11161 aatctgcttg tcttctgcaa cagaaaaaga cggtgtacgt tcttcatgaa aaggacacag
    11221 ccccaagtaa tttttaccag actttttcaa ctggacatat tgtccaatca cctcaacgat
    11281 attcgtttga ctgcgtactg tttcgataac ctcttgagga atccgttgag ccattttttc
    11341 accccctgct ctattgatat cttttgggtt taacagaaga tatttcagga gaataaccgg
    11401 taaaaaatcg cactaactga aatcagtgcg attttaaagg acacaattat acatgtttga
    11461 ttgtatcata tttcattgct ttttcaagta taacacattt ctatctcatt aagcatcaat
    11521 ttgctactct tttcagtaac tgattttgaa tatcagcctt ccagtacaat actcgaagaa
    11581 caatatttac gagcatgaat acaaagaagt atcctacgct ctctcccaac cctaagttta
    11641 cttccaaaat tccatggaac agcattgcag ctacatatat ccctacgatc gtcgttactg
    11701 ctaggaagat gcgcaatggg ttgaagggat aacaagcttt tacaactgcc atgcaactga
    11761 tcccaatcag caagtaatac atcaaagtag tagtttcagc atttccccat gcgaatgttt
    11821 ttccaagtag atacaccgca atgatattca ctactacaag caaggcattt ggtaaagcat
    11881 taataagtgc tgtaggcaaa taacggtaag tgatttttct tttatcttgt tcaaaagata
    11941 aaaagaagga aggataccct tcaatcgcta aatcaatcag cgtgatttgg atagggataa
    12001 acggaaatcc aattgctgta acggcacata taatcgataa aataaatgaa taaatcgttt
    12061 tgataaaaaa gatgcctgag actttcgtca cattgttgac cactcggcgt ccttcaaaca
    12121 ggacttctgg caatgtagta aaatcagagt ccaacaatac cagattcgca atctgacgtg
    12181 ttgctccatc accttctgcc atagcaatgc tgcaatctgc ttctcttaac gccaaaacat
    12241 cattcacacc gtcgcctgtc attgcaaccg ttctgccgct ttctttcaat tcatttacca
    12301 gcaatttctt ttgctgcgga ctcactcgtc caaaaaccgt atagcgatga gcagcttctc
    12361 gcacttccat ttcttcagta atttgagaaa gatcgacata cgcatcataa ttcggtaatc
    12421 ctgcacgtct agcgatattg gagacagtaa aaggattgtc tccagaaatc actttcagat
    12481 ccacaccttc ctcatgaaga taagctagtg tttcttgagc gttttttcgg attggatcat
    12541 cgatttcaaa cagagcaacc ggctcaacaa atgctggttt ttcttcgttc aattgctgat
    12601 ttggagcgat ccccaacata agtacgcgat agccattcgc ttgggctgtt tttagactgt
    12661 ccggaagccg atcttcttcc accaaacgtt caggcgctcc tacgtacacg actcccagtt
    12721 ctggaaattc catcgcgccc catttgcgat cagaagaaaa tgcgactttg tttgtcacat
    12781 cataccgatt agaaagctca aaataatctc tcatagcccg catagtgatg ttgttatcac
    12841 tgctttctgc cagatacgtc cccataattt ctgggatggc tttctcgtac agcggatgta
    12901 gtgcttctac ccgctggata ctcattttcc cttcagtaat ggtccctgtt ttatccaagc
    12961 ataatgtatc gacatgggcc agcgtttcaa ttgaatacat gtcttgaaca aggattcgtt
    13021 tttttgccag tttggttacc cctgtcgtta atgcaatact tattagcaat accaaaccct
    13081 ttggaagcat gcctaacaaa gctgctgcag atgcaataac agaaattttg atagaagcat
    13141 cgcggatgaa cagtgcttcc aaaaatagta tgatccccaa aggaataatc acgaaactag
    13201 tgaatttgga tactttgcga atcgaatcta caagttcaga acgaatagct ttgtgagtct
    13261 ttgcctcgct agtcaagcgg acagcataat tatctgcacc tactcggata acttcagcca
    13321 tgacagaacc gcttgtcaaa aagcttccag aaagcaattc agctccagtt tctttgacaa
    13381 tcaaatcaga ttcgcctgtc aaaagagctt catttgcttc tgcccgtcca gatataacct
    13441 gtaaatcggc tggtatctgt tctcctgctc cgatttttac caaatctcct aataccagct
    13501 ctttagtaga aatcgattgt tctttaccgt cccggatcac tagtacttct gattgggaaa
    13561 caatcgataa tttccgtaca agatttcttg catgtatttc ttgataaatt ccaataacga
    13621 tattgacgac aataattgct aaatacgcca tgttggaata cgcacctaca aataacagac
    13681 aaatcccaat accaaagttc agaaaattga ataacgtcaa tatattatcg ctgaatattt
    13741 gttttgtact ttttgatgca tcttcctggt agtcattttg ctggccagaa gccattttct
    13801 gaactacctc ttgctgtgta agtccattca ttttcttttt ctccattttc cgccaacttt
    13861 caaaaataat cacgtgttta agtctagcgt gttccaagat taaaaacaac ttgtttttat
    13921 aaaatttata gaaaaacaca cgaatgattt tacaaaaaag atgccaacct ttttgtttga
    13981 atcacccgtg tgctgttttt attatcaatc tatctttact tatattgttc ctccaaacgg
    14041 ctcatccacc aacctagtgc tgtaccggct ataaaaagaa caggacaagc tagtacccca
    14101 gcaactccca atcccgcgta atcggtagga atgatcataa tcgttgaagc aaaaactaca
    14161 cctaaaatga aatggaatag cttgctatat gcctttgaga aaatgtaatc catgattttt
    14221 gacaatccaa gaacacaaag aatcccacca attccgatcg gcacaatcac ttcaagtcgt
    14281 acttctttaa atccgtcagc catcgcttta tacaatccca tatacaccaa aaaattagaa
    14341 gggctcaatc ctgggacgat catacccaaa ccaatcaatc cgccggcaat cagccatgtt
    14401 ccaaaattct gatcgacttg cccgtcaaat aattgagcgc cgtataataa aaacaaataa
    14461 gccagaacaa aagtaacaac catgatgatc acatcagaag tatctcttcc ttttttccct
    14521 gcttctttcc ataacgcagg aacagttcca gcgatacatc cgacaaaaaa ccataatatc
    14581 gttgtttcat acgcacctaa taaaaaactg actaaaaaag aaagtagaaa gatgcctgtc
    14641 actccgccta gaccaacagg cagaaaaaac aaaacatttt ctttgaaatt ttttgtaagg
    14701 tgggctaaaa aagaaatcag ccgctcatac atgccaaaga cagctgctaa tgcaccaccg
    14761 ctgactcctg gcaagataaa tcctgaaccg ataaacattc ccttcacaaa ccgtaacatc
    14821 cagtctttgg ttgtgtaccc cacttcttga ttttccattt tttgcctttt ttccactatt
    14881 tgcgtactcc ttctttcatt taattttatt catgattgaa catttcctgc tattttactt
    14941 aaagactttt tcataggtct ctattatttt ttcattcatt ttgacaatat caggataaaa
    15001 catgttacct ccattatgat agagatagcc gccattgtaa agcaaggact ggatccgcca
    15061 atatcggtat tgtttccctt cctcatttcc taaaagtggg ctcagcacat ctttagaata
    15121 cgcttctgct aattctactg tgttttctcc gccatgattt tttacatagg caatataatc
    15181 tttcccaaaa ttatatgctt ggacagctgt ccataaatcg catccttgtt tctttgcttc
    15241 tactatcatt tccgccaaat atttgacacc ttgatcaata ctgtcagctg gattatcaat
    15301 gatctcagct tctccatgca gactttccga gctctgcatg agatctgtcc cttttccttt
    15361 tgattcggtc aatattatcg ccttgatcaa attctcgtag ttttccatat gataattttt
    15421 tgcagctgtt gttatttcta tttgatagct ttccactcgt tttaccgaac gataagttct
    15481 tcctcataaa aacaacaccg caccaataac cgtcagaatg atcatgtaaa aaagaatacg
    15541 gataatagat aatcgttttc gcttcatttc atcacctagt tattttgaca tcttttttta
    15601 tcttactatt tctttatctt cttggctatt tcttccttga tttctgtgta cgccttaaga
    15661 aaaaatgaat tttcctgtat tttttgacat cttacgaaaa tgatcgttgt ttttcagtaa
    15721 aaacaattgc ccaatgactg atataatcgt tatactttac acagtaggtg attatgtgaa
    15781 aaaagaaaag aaatatgcaa aaatgccaga tgggagcgaa atttactatg aaaagagcgg
    15841 tcaaggcttc cctctctttt tactgcatgg caatgacggc agcggccgct ttttttcaga
    15901 acaggtccct gtactcgaac gctactatac cgtgtatcta gtagatagcc gaggacatgg
    15961 tcgttcgaca aacgaagcat ctatgttgaa ttttcagtta atggccgagg atctgaatac
    16021 gatcatgttg ctggaaaaaa tcgatcaggc agattttctt ggatttagtg atggagcaaa
    16081 tctagcactg gtatttgcca gcagcttccc taaaaaagtt catcgattga ttttaaattc
    16141 tggaaacacg cttgttaaag gcgttcgttt ttctgccaga gtcatcagta atattcatta
    16201 tgcatgggta tggttactct ctttatttcg cccaagtctt cgcaaaaatc ttttagttat
    16261 caaacttttg ctgcatgaca tcgggcttac agaaaatgat ttaaaaaaaa tcaactcccc
    16321 cactttgatc atcgtgggaa aaaaagatgt aatcaagcta aaacattctt tgtatatagc
    16381 taaaactata ccaaaagctt cctttgtgct tgtgaaagaa caaggacatg aattagctag
    16441 aaaagatcct gaacgcttca atcgagaagt tcttcaattt ctttctgaaa cataactatt
    16501 aggaatagaa ggtgatttat ttgttaaaaa ataccataca atggctgaaa aaccacctag
    16561 gactgttcaa aacaatcttt ttgatttctg tcattgtcat tattgtcggt gaattgatgt
    16621 ccatcggtaa aactctatct atccagcaat taggagaaac gtttgccact atacctgtat
    16681 ggaaaagcgg actaatgcta ttgattggtc ttatctctgt gttacctatg gttggttatg
    16741 atattatttt gaatcggatg cttgaacaaa agcagaatcc tcgttacctg tttgagacaa
    16801 gctggctgat caatacgatc aacaatattg ccggtttcgg cgggtttgtt agtgtggggc
    16861 ttcgctctga actatatgga caaaagaaag agagcagaaa cgtgatccaa gcattatcga
    16921 aagttttctt gtttttgatg gctggacttt ctatttacag tctgctttct tttttacttg
    16981 tagtcttcac gccagttgct ccttttttga agcaatattg gatatggttg atcggcggcg
    17041 gtctatattt tcctgtcgtc tttttattta ctactttcaa aaagaaagga ttccttggtg
    17101 gtacctcact taaaactcaa ggacagctat tgctagtttc attgttggaa tggaccggtg
    17161 tcctgtttag tttcctttct gttggttatt taatggaaat ccggattgat ctgtggcaaa
    17221 caattccatt attcattgct gcttcagtga taggaatcgt gtctatgatt ccaggagaaa
    17281 ttgggagttt cgatgtaatg atgattatcg ggttgtccgc tattggtgtg ccaagagaaa
    17341 tagtcgttgt gtggatcttg ctctatcgcc tgttctacta catcattccg tttttgattg
    17401 gaatcgtctt tttcttcaaa aatatcggtt ccacttttga tcagcgttat tctggtatcc
    17461 ctaaacaatt agcaacagaa attgcgcata aaatcgtggt tgtcttatta tacttttctg
    17521 gaatcatgct agtactttct gccactatcc cgcaagcttt tacagagttt cgctggcttc
    17581 atagtttgaa cccattgaaa tttcatttta ttatccaatt tcctagtata ctattgggat
    17641 ttcttttaat cattatgggc agagggatcg cagcacgtgt gaaacgagca tatttgccta
    17701 caatcttctt gattgttcta gctttacttt atgttttatt aagtgatttt agtttcacac
    17761 cggtggtttt cttgtctatt ctgcttctga tcattcttgc ttctaaaaac gaattatttc
    17821 gggaacaatt gatctattca tgggagtggc gtacgatcga tggaatcatt attggtgcac
    17881 tgtccttgct ttacatcgtt attggggtat acaatctgcc ggatttccct catcggcgtc
    17941 accattttat ttcctttttc ttatttcctt ctgaaaagat ttggttttcg ggattgttgg
    18001 ccatcatcgc tgttagtttc atgatcgttc tatttgttca tttccttcaa ggagaaaaga
    18061 aacagattgg cgaagccttt aatgaagaaa aggccctgaa gatccttaca acttatggag
    18121 gaaactccga tagtcaattg atcttcttaa aagataagcg gatgtttgcc tatgaaaaag
    18181 acggtgaacc aactgttctt ctccaattcg cttgcttcaa taataaatgt attgtaatgg
    18241 gtgatccttc tggtaagaaa gaagattttc cagaagcaat cgaagctttt atcgaagaaa
    18301 cagatcgact atgctattta ccagttttct acgaaacaag cgaagagatt gttatgattt
    18361 tgcatgaatt cggctacgat ttcattaaga tgggggaaga agcttatgta gacctgaata
    18421 gttttacaac ttcagggaaa aaaatgaagg gcactcgtgc tgtcttgaat cggatcgaac
    18481 gagaaggatt tacatttgat gtcttacaac caccattttc tactgagcaa atgagtactt
    18541 tcaaaaatat ctctgataat tggttgggtt cacgaaagga aaaagggttt tctttaggct
    18601 ttttctctga agattatcta caaagagcgc ctattgcagt tgtcaaaaat acccaagaag
    18661 aaattgtcgc ttttgcaacg atcatgccta cttacacgaa caataaagta ggaacgattg
    18721 atctgatgcg atatgattct aaaaaagcac cttctggcag tatggatttc ttgttcttgc
    18781 atttgtttgc ctatatgaaa gaagaacata tccaatggtt caatttaggg atggcccctc
    18841 tttcaaatgt cggaacttcc agaaagagtt ttttacagga aaggattgca tacttggttt
    18901 acgagtttgg ttctcatttt tattctttcc atggattaag agaatataaa agcaagtacg
    18961 ctacaaactg ggtctcacgt tatactctat attctagaga tagttggatt gcatatgtta
    19021 tgattgcttt gctgattatt gataatgcgc cagttgagca gacacaaggt agaataagtg
    19081 gtttgaaaaa atggatacga agaaagtatt aaaaactgca taccgataga tgaacactct
    19141 catgatgaat aaaagagact gaagtaaaac gaaagttcat gcttctacaa tctcttctta
    19201 tacaattgaa gaacaaagag cggtccaaac agaaatcctg tttggaccgc tcttttattt
    19261 taaacatttt tcattaccaa aatattcgag tcgcgtttct tatgcttcga tctctgtaac
    19321 gatacctgaa cctactgtcc gtccgccttc acgaattgag aatgtcgttc cgttttcaac
    19381 agcgattgga tggatcaagt caacatcaat cgtcacgttg tcaccaggca tgaccatttc
    19441 tgtatcttct ggcaatgtga ttgttcctgt aacatcagtt gtgcggaagt agaactgtgg
    19501 acgatagttg ttgaagaatg gagtatgacg tccaccttct tcttttgtca acacgtacac
    19561 ttctgctttg aattttgtat gtggagtaat ggaacctggt ttagcaagta cttgtccacg
    19621 ttcgatatcg tcacgttgga tcccccgtaa caacacgcct acgttatccc cagcttcccc
    19681 gtaatctaac gttttacgga acatttctac acctgttaca actgcttttt gtgtttcagg
    19741 tttgatccct acgatctcta cctcatcacc gacacgaaca gcaccacgat caatacgacc
    19801 tgaggcaaca gttcctcgac ctgtaattga gaagacgtct tccactggca atagtaatgg
    19861 tttatctgta tcacgttctg gtgttgggat atattcatct actgtatcca tcaattccat
    19921 aatagcagct tcagcatctg gatcgccttg caatgctttt aatgcggaac ctttgatcac
    19981 aggagtgtca tcgcctggga aaccatattc gctcaataac tcgcgaactt ccatttctac
    20041 caaatcgatc aattcttcat catcgactaa atcaactttg ttcaagaaaa caatcaggta
    20101 ttttacacca acttggcgtg acaataaaat gtgttcacgt gtttgaggca tcggaccgtc
    20161 agttgcagaa acaactaaga ttgcaccatc catttgtgct gcccctgtaa tcatgttttt
    20221 cacatagtcc gcgtgtcctg gtgcatcaat atgcgcgtag tggcgttttt ctgtttcata
    20281 ttctacgtgt gcggtattga tcgtaatccc acgttcacgt tcttctggag ctgcatcaat
    20341 actagcatag tcttgaggat ttgctaggcc ttttttgcct aatactgtag tgatcgcagc
    20401 agttaaagta gttttcccat ggtcaacgtg tccaatcgta ccaatgttaa cgtgtggttt
    20461 acttctgtca taatgttctt ttgccataat ttacaaacct cctaaataat atagatcact
    20521 gaaaaatttc agctctcacc tttttattat agtctttttt tgactaaatc aaaaagaata
    20581 cgtccgactt actttttgta agattcgaac taagcttatt atacgtcaat attggtcaaa
    20641 gtcaactaag agcactcgtc tgtcttatac gcgaaaaaag taccttttat aaataaaaaa
    20701 atgtgttttt tgagaaaaac ttcaagatag tccttaactt tcttttgaag caataagaac
    20761 aaaatgagga aaagtttaaa attcagctgt tgccaacaac tttcaataga cgaaatcttc
    20821 tatttcgtta ataataagga aagaggtgaa gtacatgaaa aaattaattg gcgtacttgt
    20881 cgttttaggc atatttctcg gcggaagttt tgcagcttat cattattttt acggcggcga
    20941 agcttattat acaaaaatca cgacgaatgg cgaaatgtca gctacccaag cagataacgg
    21001 agagaaattc acgacttata cctacaagca agcggcttat aataaagatg gtgaaaaaaa
    21061 acaggtgacg cttcgcgaag aaagagaaca tccattaaag atgaatgcgt atcttaaact
    21121 caaagtcaat cctcgtaaag gtgtattaag ctgggaagaa ataaaggctt ctgaagtgcc
    21181 taaaaatgcg gcagaaaaaa tcgataatta gtaaatggtc ttaaaatttt attagataaa
    21241 a
//
LOCUS       DAFLWC010000054        20746 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.055, whole genome shotgun sequence.
ACCESSION   DAFLWC010000054 DAFLWC010000000
VERSION     DAFLWC010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20746
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.055"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            75..416
                     /locus_tag="L1V17_001788"
     CDS             75..416
                     /locus_tag="L1V17_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236555.1"
                     /translation="MEVEQIKYQGMDRERLIDIIEQQRLELIQKEAVCKEYKKHLEQV
                     IEYHSVEKYRSVVQKNRATSPDPRQDVSISIKTPVFNSVKSEKLESISTALVEKAAEM
                     NSLANEVSRLI"
     gene            complement(409..600)
                     /locus_tag="L1V17_001789"
     CDS             complement(409..600)
                     /locus_tag="L1V17_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegP family protein"
                     /protein_id="HBN1236556.1"
                     /translation="MVKNLYFVIREATNGQYYFVIKSDNNEVVATSETYLTKYSAEQT
                     INSIKNGITKDSQVIDVTK"
     gene            950..1162
                     /locus_tag="L1V17_001790"
     CDS             950..1162
                     /locus_tag="L1V17_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236557.1"
                     /translation="MNENQLRELFKTNEANKTMEATFYETQKSLALIAKQAKYFYDQL
                     ILQGFNDAQAMEFMMRTFSASNQQKE"
     gene            1169..1393
                     /locus_tag="L1V17_001791"
     CDS             1169..1393
                     /locus_tag="L1V17_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236558.1"
                     /translation="MRNYWYVSLSNKYPQPNADDPIRVVQSVQIKKKYSIIEMTREAT
                     PKEIDKYNLRYCGHGYFSEQNIQTNIERYC"
     gene            1420..1953
                     /locus_tag="L1V17_001792"
     CDS             1420..1953
                     /locus_tag="L1V17_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HBN1236559.1"
                     /translation="MVNLTPKQKAFADEYIKNGGNATQAAIKAGYSKRSARVIGKENL
                     TKPNIIQYINERLNPIEKKRKLSAEDALNELIDIWQGEVQISVSKQIDRLEKNKVIKH
                     MQYEYTPDLESKLKALDLYLKYKSLLSQTQLEKAQTEIKLMQAKLEQLQINSERSTEE
                     KLDELLEKISGELDGTS"
     gene            1940..3184
                     /locus_tag="L1V17_001793"
     CDS             1940..3184
                     /locus_tag="L1V17_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HBN1236560.1"
                     /translation="MALVDIYNPKQIDVLNKTIKNDWFITLLHGAKRSGKTKINNDLF
                     LFELRRVRKIADEEDIKEPMYILAGVSSATIQKNILQELYNMYSIEPKFDKHGNFKLF
                     GVKVVQAYTGNIGGVGAIRGMTAYGAYINEASLARQEVFAEIVSRCSGTGARILADTN
                     PDNPEHWLKKEYIDNSSKNIQSFHFELDDNTFLSERYRNNIKESTPSGMFYDRDIKGL
                     WVSAEGVVYRDFDASKHYIQSKDLPPLSNFYCGVDWGYEHWGSIVVIGETDDGTAYLI
                     EEHATQFEEIDYWVDVAKGIQERYGLRVPFYCDSARPEHVARFVREKINAKNAHKARL
                     SGVEEVAKRFKQDKLFICQDRVMKFRDEIYQYIWDKKKGEPIKEYDDVLDSVRYAIYT
                     HELLKKPKVNVNEKIKRIKRMF"
     gene            3197..4696
                     /locus_tag="L1V17_001794"
     CDS             3197..4696
                     /locus_tag="L1V17_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBN1236561.1"
                     /translation="MDKVNEFEYGADIHYSNDVNTNYVKFSVDSNLHYRFSSAEDLLN
                     DLDTLAAMIKHHHEYQVKRLSVLDDYYKARNTNIMDNRRRREKEKADHRSAHNFGKVL
                     CTFDVGYNTGNPIKVQIEDTNQQKEIEEFNTNNDIDGLNAELWLDMDKYGRAYEIIYR
                     DSDDTDYVDLANVFETFVVYDTTVKREPILAVRYPKTRFNKDADKQYIQPIVYTKEKS
                     ITYDETTLTAIELKNPQDEPHEYKEVPITEYSPNRFRMGLYEDVLSLIDLYDAGQSDT
                     ANYMTDLNDALLVISGDIEAAGLSTEDAIKQKEANMLLLESGTDVNGNKTSVTAGYIY
                     KQYDVNGVEAYKYRVRKDIHEISMVPDLTDDNFSGVQSGEAMKYKLFGFEQMTATKQR
                     LFKKGLMRRYRLLFSLKSSISEMDNSDLKGLRVIFTPNLPKAILEELKSLVDAGAELS
                     QETILGLASFVPDVQAELKRVNKETQKQIGIFDSDGEEVINNKKDETGG"
     gene            4701..5627
                     /locus_tag="L1V17_001795"
     CDS             4701..5627
                     /locus_tag="L1V17_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBN1236562.1"
                     /translation="MNSQEYWIKREKEWQKQQIKDDKKRMAEIKSRMQYAQDAIQKEI
                     DAQWDSFSNGQKITRSEAMKRASEMDVKAFARKAKKYVKEKDFSPTANQELKLYNLTM
                     RVNRLELLKANIGLELISLFNELDKYFSNELTKAGLAELKRQAGILEMTIASSGYAKL
                     IELVINSSFLSDDVSFSDRLWMYQSELKSELDRLLVRSITMGKNPKQLASKLAEYLTA
                     EGRENTKFNTQRLMVTETTRVQVGIQERSYRDAGITQYIYIAEPTACKLCIPLNNQVF
                     DVADMQPGSNAPNMHPFCRCSTAPYIERISSR"
     gene            5754..6356
                     /locus_tag="L1V17_001796"
     CDS             5754..6356
                     /locus_tag="L1V17_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HBN1236563.1"
                     /translation="MKKRLFMPMNLQFFSEPGDGGSGDEGQQGNLPAGSQETPPEAKE
                     ENNTGKTFSRDEVAKMIAAETNKAKAAWEKELAAKKEEAKKLAKMNAEEKLQHELEQK
                     EAEIAELKRGQALSEMTKEASKMLTDANLPHDDDLLGLIVSDDADATKQAVAVITNFA
                     SLIKRENARQTPPNEGGQFTASKNTKETVAKLAAKNRIIK"
     gene            6369..7292
                     /locus_tag="L1V17_001797"
     CDS             6369..7292
                     /locus_tag="L1V17_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBN1236564.1"
                     /translation="MKKKQLLPMNLQMFAQTWDPDNVLVYETKEGKIPDKYNTLILSE
                     VMENSKIMQLAKYEEMTDKEKKFEYFAEGPGAYWVGEGEKIKTSKPKWMQATMTAKKL
                     GVILPVSREYLNYKLSDFFEEMQPKIAEAFYKKFDAAALLNKENPFPQSLDGSVISAG
                     NVVEGGLTYDNILALEDKLAENEFEPNAFISNRKNRTELRSAAQTVGSNVEFIYDRST
                     NTIDGLPVVDLKSLDKGTLYAGDFNYMFYGIPYNISFKISEEAQLSTLTNEDGTPVNL
                     FEQELIALRATMDVGFMIVKDEAFGKISPKA"
     gene            7310..7573
                     /locus_tag="L1V17_001798"
     CDS             7310..7573
                     /locus_tag="L1V17_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236565.1"
                     /translation="MPNQKTWTGKVGDTKTFTISAVPADASDAAAVVAATTATSSDGA
                     IATVTKNENGGFDGTIAAEGSATFTFTSGEFTTSINVTGQPAS"
     gene            7585..7914
                     /locus_tag="L1V17_001799"
     CDS             7585..7914
                     /locus_tag="L1V17_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HBN1236566.1"
                     /translation="MMIADDIKKLLKGTIDEKLEVIERRTNERMKTLLNTQEVPKEFE
                     TVVYEVSLKRFNRIGQEGMQSYSQEGLSMAFPDSDFSEYQNEIDEFKRKDQEELYKPK
                     RGRFKFV"
     gene            7911..8237
                     /locus_tag="L1V17_001800"
     CDS             7911..8237
                     /locus_tag="L1V17_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236567.1"
                     /translation="MRFTDEIIFVKRSSDSKYDPDLGEWVEGKPERTRTEANVTDIGT
                     DRSVTIFGSVEEGAKVIRTQPLFSIPTFDYIEIEGKTWQQKTARNPAYRNSLIVQEVV
                     LDEGTT"
     gene            8221..8559
                     /locus_tag="L1V17_001801"
     CDS             8221..8559
                     /locus_tag="L1V17_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBN1236568.1"
                     /translation="MKAQLEYKGIDQLMRHLKKAATLNDVQKVVKSNTAEMTERMQKG
                     APVDTGYLRRSINMNLLEAGLTGIVGPTADYAPYVEYGTRFMSAQPYVRPAFNYQKVK
                     FMAEMKALVK"
     gene            8559..8951
                     /locus_tag="L1V17_001802"
     CDS             8559..8951
                     /locus_tag="L1V17_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HBN1236569.1"
                     /translation="MIKTRDQSIFDELFKISQNKLGYKTYDYKTLEDVGYPFVEFENT
                     QTIHEVNKTDIKGSVIVVLSVWGLQKKRKQLSDMASALFNEARLIEATEGYYWALNYQ
                     ASGIQVMDDTTTNTPLKRAVVTLEFRIR"
     gene            8962..9474
                     /locus_tag="L1V17_001803"
     CDS             8962..9474
                     /locus_tag="L1V17_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HBN1236570.1"
                     /translation="MEALKGIDVILLYRLLKKETQEAAWKMAFQTEHENGLSRDSDST
                     VTKDGNVQSLSPVEYDFSATSIVAKGDSHVDEMKQALLNGDIIEIWEINKAEQGTDDN
                     ANKYKATYYQAYVSEFTPSAAAEDNVELSLSFAVNGVGQDGYATLTEDQADVVQYAFK
                     DTVKATSTGA"
     gene            9520..9888
                     /locus_tag="L1V17_001804"
     CDS             9520..9888
                     /locus_tag="L1V17_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly chaperone"
                     /protein_id="HBN1236571.1"
                     /translation="MKLKIKGKEYSFKFGTKFVRELDKVMPFVDGNMEFGMGLSAKVL
                     PELRSYNVNTLSRVLEIANRTEDESITLDELDDYIDEVKDIEKLFDEVLKELAESNAG
                     KLAVRNLNQKLKEAEKQQVE"
     gene            9942..10229
                     /locus_tag="L1V17_001805"
     CDS             9942..10229
                     /locus_tag="L1V17_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236572.1"
                     /translation="MTNISDIERMTLYEYNIRMTAAQLSWLDKEKLIHELAWANQQVQ
                     AEKKVGKKTVPVYRSFEEFFNYQKIEDSIMGVSELSKQDKKFQSLLTKANS"
     gene            10246..13365
                     /locus_tag="L1V17_001806"
     CDS             10246..13365
                     /locus_tag="L1V17_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBN1236573.1"
                     /translation="MEQFSVEALLKATDSGFVKTFKDAQDAVKTFEKNSNSMTTAVGK
                     VMQGTGAAMTKYITTPLIGVGVAAAKVGGDFEAQMSRVKAISGATGDTFEQMKQQAID
                     LGAKTAFSAKESAAGMENLASAGFSAQEIMKAMPGLLDLAAVSGGDVALASENTATAL
                     RGFGLEASEAGHVADVFARAAADTNAEVGDMGEALKYVAPVANSMGISLEETAAAIGI
                     MSDAGIKGSQAGTTLRGALSRLARPTKAMQDTMDNLGVSFYDADGKMKPLKTQVELLK
                     KAFEGLTPEQQQNALVTLYGQESLSGMMALIDKGPDSLGKLTKSLKDSDGAADDMART
                     MQDNMNSSIEQMFGAFESAAIVIQKILAPSIKKVADAISGLVEKFVSAPESTQKLVVA
                     IGAIVAAIGPLIFMIGSVIIWINRVKVAFKALSESSKLFSGLSKAMGLLTNPVFLVIA
                     AVALLVVGFIYLWNTSEDFRNFWIGLWEGIKSAVSSAVEWIQNAWKSTGEWFNNLWKS
                     IKEGADNVWTTVQEAPGKAADWIKNKWTGTKEFFSNLWSSIANSASEIWNSLKEGVIS
                     VIDDLVSSAGEKWEGFKNTISTAWKTITSKIKSGFDFILKYIGPFVSSFSDVFSNIVK
                     AITSIFAEVKNIIVNAWEIIKSLIAAPLLFIIDLITGDFEQMKEDLDLIWNTLVQSVV
                     NIWTSVKNIFTEYIGAIVNSAVSLWTGFIQSISNIWNEVVYQATMIWIDLKLFFTNLW
                     IDIKYSAIQMWINLKFSIIQTWIDTKYGAIELWNNLKQWFFQTVNNIVQTLIKSWNSL
                     KQGTIDLFNNTVQGAKDIWTSFKSWIGDLITGTKDNIIQGWENLKQGTIDTFNNLVNG
                     AQEAWDNLVNAVSDTVDRVTGWFDNLKNIDLLAAGKAIMDSFLEGLQNAWKSVQDFVG
                     GIGDWIREHKGPIQYDRKLLIPAGQAIMNGLNKGLTGGFNDVQNTVGSMADFIAELFN
                     ANSDVDIAANLKNANKNIGAQVEHKINMGGSTKPAVFKINLGRQSFRLFMDDISQAMG
                     EGADINLEF"
     gene            13398..14165
                     /locus_tag="L1V17_001807"
     CDS             13398..14165
                     /locus_tag="L1V17_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HBN1236574.1"
                     /translation="MYSFKDTTINLTSSKRFLPTSAMMYDGMYLEDLIDGYQTLTVEG
                     REMLSVEVEQQEIQIGSIITNQKIPSRTLKITYKLEDRDPEKLQFKFKELLNYLYRNE
                     DVEIRFHDELDYYYYGRYTSTDTVPGDSNSIISSFNVFCADPLKYTKECVSDGYIGNP
                     IQFPITPRKIEVTLSMNNSIKITNGEQNITITDAAIKTGDVLVFDFSDEQVTVNGEDC
                     TSMIDLESDFENFYLKQGQKITSNNGKLKIFYRGATI"
     gene            14162..16993
                     /locus_tag="L1V17_001808"
     CDS             14162..16993
                     /locus_tag="L1V17_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HBN1236575.1"
                     /translation="MSETVYFFDHLQKLIKRKNTRSLIEVSQEKEISSDKSDLMKDTL
                     YVTTKYDKEIEDARYMAIRENESSFSLYRITKVSDPFETLEFTGLGFATNELDAYIIK
                     DIRPSGQPLKNVLDRLIEFTEGNWRVGHVEAMLPTVTATFYYVSVKEALKELQTLGME
                     FVFRCSLNSDGIKDKWIEVYEQIGEESNTRFVYGSKALTVVREIDRSSISTSMIGRGR
                     GEEVGDGYGRRIEFTDVEWKKSNGDPLDKPKGQNWLEDPESTQKYGIPQKDGSMRKRE
                     TVVVFDDIDDPTDLLKNTYSTLIDSARPLVQFKAEVTGGDVIGNTVTIHRYDKGYHYK
                     TRIYKTTFNRLTGQTNIELGDNLTQDVRKQTASIVNNINSLESSKMTFYESTEIGKYQ
                     DDIMRGAGDNGGSIYWVNGIEAGVSDSREIYETVYMDGPNIPRSRFFMVQNNSGISFK
                     QCKKGEWQTIQDVHNGDSTTAWTLDGTFNANFIRAGILSGILVQGVALKTFDDKDFQL
                     VAEGGELSFEKQVKSTGLDDVHGERLGSIVSTYGSKGINGFAVWKEPNYIFSINAGDG
                     GDRGNPIFQIPADVTADKRKYNLYGDGNFSEGNITIDGRLDVKELYVNGTKIDTNGGG
                     NSGGNDNGWNGQYPPEVTTDRDKRYWQIWATAIGAGFTQQAAAALLGNAQGESDANPT
                     ADEGNGAPGFGYGVWQWTDSSGATSGRVYMINLMTKAGISDDPDTITAQFKLLMWHAP
                     NGQWIATSAYPYTWTQFMNLTDINTAAQAFVANFERPRDPHPERTAWSQEWYDKFKDL
                     EIPVSKGYMKPIADPITVTSEFGWRTSPITGAQEFHNGIDLVNGNPNTPIFASADGEV
                     IVAGDANYFDWYGNWTVIKHADGMYTGYAHQSRVDVSKGQKVTAGQQIGLMGTTGPST
                     GEHLHFQFMDEFYPSSSGHFHNARDYIDF"
     gene            16968..18725
                     /locus_tag="L1V17_001809"
     CDS             16968..18725
                     /locus_tag="L1V17_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HBN1236576.1"
                     /translation="MQETTSISKGGIVMAETQHKMVLSTTEPNNGINLVRIRQGDVLT
                     QKFVVEVVEHGKLKTFEGLVPFFINTTKFGENQPVEQKVQEYSPAQARLVYTLSEPDW
                     QWGGENTAHFSFRSLNGDGTWSEQFSTQDFTYRVISGISRSQLRDSGYVWTFEDLLRK
                     FKDYMDQGKNDWEQWLEDNREILENIDPGGMIINILNEAKGDYESLADRLNQKYQVPV
                     GSSQIRETTRFFDYDTMKYVDLVPRNLNTVVNSVNNSKFNFSFITDIHADNHNLRIDG
                     VGYKDASYLRHWRAIPQFQKLGNKTDVMIYGGDNIDGGLGSLGSDIGIIDEWSARHSM
                     LGTLKRFTNAAVAGQEKPVIICKGNHDACFDPAWRKRKGMLCNADFEEYWNGLYGGVL
                     FPDKNAAIYRFDTCDFYEGGTGDKYVDGYSDTAPGAFSAKQINAFGEWLVNVPRNYHV
                     ALVGHTPLGLSKFPVRNENMISTLIEGFKSGSPVTIDWSKLGQPNDGSFGGLKTFAMN
                     TKGAGVVVGYFCGHWHEQVEGAFGTVKMILCDVGFSHTASQVDTPDELAFYKIEVDTA
                     TRKVTSKGVGRARDFTYNY"
     gene            18742..19524
                     /locus_tag="L1V17_001810"
     CDS             18742..19524
                     /locus_tag="L1V17_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236577.1"
                     /translation="MLDFQSKPNIFEEMSYEEAVKWLLRQAAIHYDGSDHDAHVLATE
                     SNAGFATPETVMQARGRWLRDYKLPQKYPNILDIPPGKYATKAGWGADNPDGIEDDSF
                     VEMMVFADHDSRKLIVAFARYSGEIYIKMTHNSEPVEGYNSLGWRRVYTTSVLFEGEL
                     RKGQSVNLPDDTFRYQTLRIHYTDGDGDFVEEVKRQRYARITKANLWNGDAGVTFIEF
                     ELTIEARKITMSNGRALDISSGNVSNPAMSNNVKITKIEGVK"
     gene            19524..20525
                     /locus_tag="L1V17_001811"
                     /pseudo
     CDS             19524..20525
                     /locus_tag="L1V17_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321067.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
BASE COUNT         7259 a         3341 c         4522 g         5624 t
ORIGIN      
        1 caactccttc taaattgttc ttattatcta tcatccgttg ctgtttatta atttatgtat
       61 tggagggaaa acgaatggaa gtcgagcaaa taaagtatca aggtatggat cgggaacggt
      121 tgattgatat tattgagcaa caacgtttag aattgatcca aaaagaagct gtatgtaaag
      181 agtacaaaaa acatttagaa caagtaattg agtatcattc agtagaaaag tacagatcag
      241 tggtgcaaaa aaatagagca acgagtcctg atcctcgtca agatgtatcg attagtatca
      301 agacgccagt atttaattct gttaaatcag aaaagctaga aagtatctca actgctttgg
      361 tagaaaaagc agctgaaatg aactccctag caaatgaagt tagtcgtctt atttagtcac
      421 atcgataact tgagagtctt tggtgattcc gttttttata gaattaatgg tttgttcagc
      481 ggaatattta gtcaagtatg tttcgctagt tgctactact tcattgttat cggacttaat
      541 aacgaagtaa tattggccat tagttgcttc tcttataaca aagtacaaat ttttcaccac
      601 cttttaattt atttcagcgg accactcgct gataaataaa attatacact tagtatttat
      661 tttcacaata ttaatttgtc actgtggcgg aaagggtaga cgctaagcat gtgtgttagg
      721 tcaatgcttc ggcaaccatg caaggttcga ttccttgcca gtgactttgg caactgaggg
      781 ttggaaatgg gcgctcaaag tacacgagca aggcgaggtc gatagtaatc gatggaatcg
      841 gtgtaggttg cttgatagaa ctataactgc atctcgttta tgaggtgtag tttttacata
      901 ttagatcact catcgagtgg tctttttatt ttggaagggg agtaaaaaaa tgaacgaaaa
      961 ccaattaaga gagttgttta aaacgaatga agcaaacaaa acaatggagg cgacattcta
     1021 cgaaactcaa aaaagcttag cgttaatcgc aaaacaagct aagtatttct acgatcagct
     1081 tattctgcaa ggatttaatg acgcacaggc tatggaattt atgatgcgaa ccttttctgc
     1141 cagtaaccaa cagaaagagt gatacgtaat gaggaactac tggtatgtat cattatcaaa
     1201 taaatatccg caaccaaacg cagatgatcc aattagagtt gtccagtcag tccagattaa
     1261 aaagaagtac tccatcattg aaatgaccag agaagctacg ccaaaagaga ttgataagta
     1321 caatcttcgt tactgcggcc atggatattt tagtgagcag aacatacaga caaatattga
     1381 gagatattgt taataaaatt gaaaggtggt ggcttgaatg tggtaaattt gacaccaaaa
     1441 caaaaagctt ttgcggatga atatataaaa aatggtggta atgctactca agccgccatt
     1501 aaagcaggtt atagcaaacg atcagcaaga gtaataggta aggaaaacct aactaaacct
     1561 aacataatac agtatattaa tgaacggcta aatcctatcg aaaagaagcg caaattaagt
     1621 gccgaggacg ctttaaatga attgatagat atttggcaag gagaagtaca aataagcgtg
     1681 agcaagcaaa tagaccgctt ggagaaaaac aaggttatta aacatatgca atatgaatat
     1741 acaccagatt tagaaagcaa attgaaagcc ttggatttgt atttgaagta taaatcgctg
     1801 ttatcacaaa cgcaattaga aaaagctcaa acagaaataa aattaatgca agcaaaatta
     1861 gaacaattac agataaactc agagcgttct accgaagaaa aacttgatga gttgttagaa
     1921 aagattagtg gtgaattaga tggcactagt tgatatttat aacccaaagc aaatcgacgt
     1981 gttaaataaa accattaaga atgattggtt tattacttta ttacatggag caaaacgttc
     2041 tggaaaaaca aaaataaaca atgatttgtt cttgtttgaa ttgcgacgtg tgcgaaagat
     2101 tgccgatgaa gaagacatta aggaaccaat gtatatccta gcaggagttt caagtgcaac
     2161 aatccaaaag aacatcttac aggaactata caacatgtac agcatagaac ctaaattcga
     2221 taaacatgga aactttaagc tatttggcgt taaggtcgta caagcttata caggaaacat
     2281 tggcggtgtt ggcgcaattc gtggtatgac agcatatggc gcttatatca atgaggcatc
     2341 gctagctaga caagaagtat ttgctgaaat cgtttcacgt tgttcaggaa caggagcgag
     2401 aatactagct gatacaaacc ctgacaaccc ggaacactgg ctaaagaaag agtatatcga
     2461 caattcaagc aaaaatattc aatcgttcca ctttgaatta gatgataata catttttatc
     2521 tgaacgatat cgtaacaata ttaaagaatc aacaccaagc ggcatgtttt atgatcgtga
     2581 tatcaaaggt ttatgggttt ctgcagaagg tgtcgtttat cgtgattttg atgctagcaa
     2641 gcactacatc cagtcaaaag acttaccacc tttgagcaac ttttattgtg gtgttgactg
     2701 gggatatgaa cactggggtt caatcgtagt tataggtgaa acggatgacg gaacagctta
     2761 tttaatcgaa gaacatgcta ctcaatttga agagattgat tattgggtag atgtggcaaa
     2821 aggcattcaa gagcgttacg gcttacgagt acctttttat tgtgactctg cgagaccgga
     2881 gcatgtggct aggtttgtaa gagaaaagat taatgctaaa aatgctcata aagcacggtt
     2941 atctggagtt gaggaagtcg ccaagagatt taaacaagat aaattgttta tctgtcaaga
     3001 tagagtgatg aaatttcggg atgaaattta tcaatacatt tgggacaaga aaaaaggcga
     3061 gccaataaaa gaatatgatg atgtgctaga ctccgttcga tatgcgatat atactcatga
     3121 gcttcttaag aaaccaaaag ttaatgtcaa cgaaaagatt aaacgtatta aacgcatgtt
     3181 ttaaggagtg tgaaaaatgg ataaggtaaa cgagtttgaa tacggagctg atatacatta
     3241 ttctaatgac gtgaacacaa attatgtaaa gtttagcgta gactcaaatc ttcactatag
     3301 atttagctca gcagaagatt tacttaacga tttagatact ttagcagcaa tgataaaaca
     3361 tcatcatgaa tatcaggtaa aaaggctaag tgtattagat gattattata aagctagaaa
     3421 tacaaatatc atggataacc gtaggcgcag agaaaaagaa aaagcggatc accgatcagc
     3481 acataacttt ggaaaagttc tttgtacgtt tgatgttggg tacaacacag gcaatcctat
     3541 aaaagtgcaa atcgaggaca caaatcaaca aaaagaaatc gaagagttta atactaataa
     3601 tgacatagat gggttaaatg ctgaactctg gcttgatatg gataagtatg ggagagccta
     3661 tgagattatc tatcgagatt cagatgatac agattatgtt gatttggcta atgtatttga
     3721 aacgtttgtt gtatatgata ctacagtaaa acgagagcct attttggctg tacggtatcc
     3781 taagacaaga ttcaacaagg atgctgataa acagtacatt caaccaatcg tatacacaaa
     3841 agaaaaaagt atcacttatg atgagacgac actaacagca attgagttaa agaatcccca
     3901 ggatgaaccg catgaatata aagaggtacc tattacagag tattctccta atcgttttcg
     3961 gatgggcttg tatgaagatg tactatcttt gattgatcta tacgatgcag ggcagtctga
     4021 taccgccaat tatatgactg atctaaacga tgctcttcta gttattagtg gtgatattga
     4081 agcagcagga ctatccacag aggacgccat caagcagaaa gaagcgaata tgcttttgct
     4141 tgagtctgga actgatgtga acggtaataa aacaagtgtg actgcaggat atatttacaa
     4201 acaatatgat gtgaacggtg tagaagcata caaatacaga gtacgcaagg atattcacga
     4261 aatatccatg gttcctgatc ttactgatga caatttttcc ggagtgcaat cgggagaagc
     4321 aatgaaatat aaattatttg gatttgaaca aatgacggca acaaagcaaa ggctattcaa
     4381 aaaaggcctt atgcggcgtt atcgtctttt atttagccta aaatcaagta tttctgaaat
     4441 ggataactcc gatttgaaag gcttacgtgt aatatttacg cctaatctac ctaaagccat
     4501 tctggaagag ttgaaatctt tggttgatgc tggagctgaa ctcagtcaag agacgatctt
     4561 aggactcgct tcttttgttc cagatgtaca ggcagagttg aaacgagtaa ataaagaaac
     4621 gcaaaagcag attggcattt ttgattcaga tggtgaagaa gtaattaaca acaaaaaaga
     4681 tgaaacaggg gggtgattaa atgaactccc aagaatattg gatcaaacgg gaaaaggaat
     4741 ggcaaaagca acaaattaaa gatgataaaa agcgcatggc agaaattaaa agtcgcatgc
     4801 aatacgcaca agatgcgata caaaaagaaa tagacgcgca gtgggacagt ttctccaatg
     4861 gccagaaaat cactcgtagc gaagcgatga agcgtgctag tgaaatggat gtcaaagcat
     4921 tcgctcgcaa agcaaagaag tatgtcaaag agaaagattt ttctcctaca gcaaaccaag
     4981 aattaaagct atacaatctt acgatgcgtg taaatagatt agagctctta aaagctaata
     5041 tcgggcttga attgatttca ctgtttaatg aattggataa gtacttttcg aatgaattaa
     5101 caaaagctgg tttagctgaa ttgaagagac aagccggtat tttagaaatg actattgctt
     5161 caagtggata tgcaaagctg atagaactag taataaacag ctcctttttg agtgatgacg
     5221 tgtcttttag tgatcgctta tggatgtatc aatctgaatt gaaatcagaa ttagataggt
     5281 tgttagtcag aagtataacg atggggaaaa atcccaagca acttgcatct aaattggcag
     5341 aatatttaac agctgaagga cgagaaaaca ctaagttcaa cactcaacgt ttgatggtga
     5401 ctgaaacgac tagagttcag gtagggattc aagaacgaag ttatagagat gcaggcatta
     5461 cccagtacat ctatatagca gaaccaacgg cgtgcaaact atgtataccg ttaaataatc
     5521 aagtttttga tgttgccgat atgcagccag gaagtaacgc tcctaatatg catccatttt
     5581 gtcgatgcag tacagcacct tatatagaac gaatatcaag ccgttaacac aaattaacgg
     5641 ctttttattg tgccttctta cagcttacag gcgttaaaga gaaagctatt ttcggctgac
     5701 cggcgtaact ggtcaaattt atcgggtagc ggcgtaaccg tggaggatta atcatgaaaa
     5761 aacgtttatt tatgccaatg aacttacaat ttttttctga accaggagat ggtggatctg
     5821 gtgatgaggg acaacaagga aacctaccag ctggctcaca agagacaccg cccgaagcaa
     5881 aagaagaaaa caatactggc aaaacatttt ctcgtgatga agtagcgaaa atgatcgctg
     5941 ctgagacgaa taaagcaaaa gcagcgtggg aaaaagaact agcagcaaaa aaagaagaag
     6001 ctaaaaagct ggcaaaaatg aatgcggaag aaaaactaca gcatgagttg gagcaaaaag
     6061 aagctgaaat cgctgaatta aagcgtggac aggcactatc tgaaatgacg aaagaagctt
     6121 ctaaaatgct gacagatgca aatttaccac acgatgatga tttacttggt ctgattgttt
     6181 ctgatgatgc agatgccaca aaacaagctg tagcagtcat cactaacttt gcttctttga
     6241 ttaagagaga aaacgcaaga caaacaccac caaatgaagg tggacaattt acagcatcga
     6301 aaaatactaa agaaacagtg gctaaactag ctgctaaaaa tcgaattatc aaataggagg
     6361 aaaacttaat gaaaaagaaa caacttttac caatgaactt gcaaatgttt gctcaaacat
     6421 gggatccaga taatgtcttg gtatatgaaa cgaaagaggg aaaaattcct gataaatata
     6481 atacgctcat tttgagtgaa gttatggaaa attctaagat catgcagtta gcaaaatacg
     6541 aagaaatgac tgacaaagaa aagaaatttg aatactttgc agaaggacca ggcgcatact
     6601 gggtgggtga aggtgaaaaa attaaaacgt ctaaacctaa atggatgcaa gctacgatga
     6661 ctgcaaaaaa actcggtgtc attcttccgg tttctcgtga atatttaaat tataaattat
     6721 cagatttctt tgaggagatg cagccaaaaa ttgctgaagc tttctataaa aaatttgatg
     6781 cagctgcctt attaaataaa gaaaacccat ttcctcagtc actagacgga tcagttatta
     6841 gtgcggggaa tgtggttgaa ggcggattga cttatgataa tatcctagcc ttagaagaca
     6901 agttagcaga aaatgaattc gaacctaatg cgtttatttc aaaccgaaaa aatcgtacag
     6961 aattacgttc tgcagctcaa acagtcgggt caaatgttga gtttatttat gatcgctcta
     7021 ctaatacaat tgacggatta ccagtagtag accttaagtc tttagataaa ggaacacttt
     7081 acgctggaga ctttaattac atgttttatg ggatcccata taatatttca tttaagattt
     7141 ctgaagaagc ccaattgtct actttaacta atgaagatgg aaccccagtt aacttgtttg
     7201 agcaagaact gattgctttg cgtgcaacaa tggatgttgg atttatgatt gtaaaagatg
     7261 aagcatttgg gaagatttcc ccaaaagcgt aacgcctgct accggtattg tgccaaatca
     7321 aaagacatgg accggtaaag taggcgatac taaaacattt actatttcag ctgtgcctgc
     7381 agatgctagc gatgcagctg ctgttgttgc agctactaca gcaacttcaa gtgatggagc
     7441 tatcgcaaca gtgaccaaaa atgaaaatgg tggttttgat ggaacgattg cagcagaagg
     7501 gtcagcaaca ttcacattta cttctggaga attcactact tcaatcaatg tgacaggtca
     7561 acctgctagt taggaagtaa aaatatgatg attgcagatg atattaaaaa acttcttaaa
     7621 ggaacaatag atgaaaagct tgaagttatt gagcgaagaa cgaatgagcg tatgaaaacc
     7681 ttgttaaata cgcaagaagt tcctaaagaa tttgaaacag ttgtatatga agtatcgttg
     7741 aaaagattca atagaattgg tcaagaaggt atgcagtcat attctcaaga aggtttatct
     7801 atggcttttc ctgactcgga tttttcagag tatcaaaatg agattgatga atttaagcgt
     7861 aaagatcagg aagagttgta caagccaaag cgagggaggt ttaaatttgt atgagattta
     7921 cagatgaaat tatatttgtt aaacgttcat ctgactctaa atatgatcca gatctcggtg
     7981 agtgggttga aggcaaacca gaaagaacaa gaacagaggc aaacgtgaca gatattggca
     8041 ctgatagaag tgtgactatt tttggtagtg tggaagaagg ggcgaaggtc attaggacgc
     8101 agcctctttt ttctatccct acatttgact atatcgagat tgaaggaaag acttggcaac
     8161 aaaaaacagc tagaaatcca gcatatagaa atagtttaat tgtgcaagag gtggttcttg
     8221 atgaaggcac aacttgaata taaaggaatc gatcagctga tgcgacatct gaaaaaagca
     8281 gcaacgctta atgacgttca aaaagtcgtg aaaagtaata ctgctgaaat gactgaacga
     8341 atgcaaaaag gtgcgccagt ggatacaggt tacttacgaa gatcaataaa catgaatctt
     8401 ttagaagctg gtttaactgg tattgtagga ccgacagcag attatgcacc ttatgtagaa
     8461 tatggcactc gatttatgtc ggcacagcct tatgttagac cagcgtttaa ttaccaaaaa
     8521 gtcaaattta tggctgaaat gaaagccttg gtgaaatgat gattaagaca agagatcaat
     8581 caatttttga tgaacttttt aaaatatccc aaaacaaact tggatataaa acatacgatt
     8641 acaaaacttt agaggatgtt ggttatcctt ttgtggaatt tgagaacact cagacaatcc
     8701 atgaagtaaa taaaactgac attaaagggt ctgtgattgt ggttttatcc gtttggggat
     8761 tacagaagaa acgaaagcag ttgtcagata tggcatctgc tctttttaat gaagctagat
     8821 tgatagaagc cacagaaggc tattattggg ctttaaatta tcaagcaagt ggaattcaag
     8881 tgatggacga cacaacaacg aatacaccgc taaaacgggc ggttgtcaca cttgaattta
     8941 gaattagata ggaggaagaa catggaagca ttaaaaggta ttgatgtcat tttgctttat
     9001 cgcttattga aaaaagaaac tcaggaagcc gcttggaaaa tggcatttca aacagaacac
     9061 gaaaatggtt tatcaagaga ttcagactct acagtgacaa aagatggaaa cgttcaaagt
     9121 ttaagcccgg ttgaatatga tttttcggct acttcaatag ttgctaaagg agattctcat
     9181 gtagatgaaa tgaaacaagc tttattaaat ggggatatca ttgaaatttg ggaaattaat
     9241 aaagcagaac agggaacaga tgataatgca aataagtaca aagctactta ttaccaagca
     9301 tatgtgtctg aatttactcc atcggctgct gcagaggata acgttgaatt aagtttatca
     9361 tttgcagtaa atggtgttgg tcaagatggt tatgcaacct tgacagaaga tcaagccgat
     9421 gttgttcaat atgcattcaa agataccgtg aaagcaactt cgacaggagc ataagagggc
     9481 ttagatgctc tcttttttat tttaggagga tgaaaaacat tgaaattaaa aattaaaggt
     9541 aaagaatatt cgtttaaatt tggcactaaa tttgtacgtg aattagataa agtgatgcct
     9601 ttcgtcgatg gaaatatgga atttggaatg ggactctccg caaaagtctt accagagcta
     9661 cgttcttata acgttaacac gttatcacga gttctggaaa tagcaaatag aactgaagat
     9721 gaatctatta cattagatga attggatgat tacatcgatg aagttaaaga cattgaaaaa
     9781 ttgtttgatg aagtcctaaa agaattggcg gagtcgaacg cgggaaagtt agcggtccga
     9841 aacctgaatc agaaattgaa agaagcggaa aaacaacaag tggaatagat tctgcactgg
     9901 catacgaaca aattcttatc aattcttttc gatatttggg aatgaccaat atctcagata
     9961 tcgaaagaat gacgttatat gaatacaaca ttcgtatgac tgcagcccag ttatcttggc
    10021 ttgacaaaga aaagttgatt cacgaattag cgtgggcaaa tcagcaagtc caagcggaga
    10081 aaaaagtagg caaaaagaca gttcctgtat atcgatcctt tgaagaattc ttcaattatc
    10141 aaaaaatcga agattcaatc atgggagttt ccgaactttc aaaacaagat aaaaaattcc
    10201 aaagcttact aactaaagct aactcttgag gaaaggagga gaatcatgga acaattttct
    10261 gttgaagcct tattaaaagc cacagatagt ggatttgtaa agacttttaa agatgcacaa
    10321 gatgctgtta aaacttttga aaagaattca aatagtatga caaccgctgt tggtaaagtg
    10381 atgcaaggta ctggtgccgc aatgacaaag tatattacca ctcctcttat aggagtaggc
    10441 gtagcagctg ctaaagttgg tggcgacttc gaagcacaaa tgagtcgtgt aaaagctata
    10501 tcaggagcaa ccggcgacac attcgaacag atgaaacagc aagcgattga tctaggagca
    10561 aaaactgctt ttagcgcaaa agaatcagct gctggaatgg aaaacttagc ttctgctgga
    10621 tttagcgcac aagaaatcat gaaagcaatg ccgggtcttt tagacttagc agctgtatct
    10681 ggaggggatg tggctctagc ttctgaaaat actgctactg ctttgagagg atttggttta
    10741 gaagcaagtg aagcaggaca tgtcgctgat gtatttgctc gtgctgctgc ggataccaat
    10801 gctgaagttg gagacatggg agaagcattg aagtatgttg ctcctgtagc taattcaatg
    10861 gggatttctt tggaagaaac tgcagcagct attggtatta tgagtgacgc aggcattaag
    10921 ggttctcaag caggtacaac gttgcgagga gcattgtcta ggttagcaag gccaacaaag
    10981 gctatgcaag atacaatgga taatttaggt gtttcgtttt atgatgctga cggtaaaatg
    11041 aaacctttaa aaactcaagt agaattactt aaaaaagctt ttgaaggcct gacgcctgaa
    11101 caacaacaaa atgctttagt aacactatat gggcaagaat cattatcagg gatgatggct
    11161 ttgattgata aaggacctga ttcattgggc aaattaacaa aatctctgaa agattctgat
    11221 ggtgcagctg acgatatggc tcggaccatg caagataata tgaattcttc catcgagcaa
    11281 atgtttggag cttttgagtc agcagctatt gtaattcaaa agattctagc accatccatc
    11341 aaaaaagtag cagatgccat atccggctta gtagaaaaat ttgtaagtgc tccagaatca
    11401 actcaaaaat tagtagtggc cataggagca attgtcgctg ctataggacc gttaattttt
    11461 atgattggtt cagtaattat atggatcaat agggtgaaag tagcttttaa agctttaagt
    11521 gaaagttcaa aattgtttag tggattaagt aaagcaatgg gtcttcttac aaatccggtt
    11581 tttctggtta tagctgcggt agcactactc gttgtaggtt tcatctatct ttggaatacg
    11641 agtgaagatt ttagaaactt ttggattggc ttatgggagg gaatcaagtc tgctgtaagc
    11701 tcggcagtag aatggattca gaatgcatgg aaatctacag gagaatggtt taacaattta
    11761 tggaagtcca ttaaagaagg cgcagacaat gtttggacta cagttcaaga agcccctggg
    11821 aaagcggcag attggattaa aaacaaatgg actggaacaa aagagttctt ttcaaattta
    11881 tggtcaagta ttgcaaactc tgcttcagag atttggaata gtttaaaaga aggtgtcata
    11941 tcagttattg atgatttagt ttcaagtgct ggtgaaaaat gggaagggtt taaaaatact
    12001 atatctactg catggaaaac aattacaagt aaaatcaaat ctggttttga ttttatacta
    12061 aaatatattg gtccatttgt aagtagcttt tcagatgtgt tctctaatat agtgaaagca
    12121 ataacaagta tatttgctga ggttaaaaac ataatagtaa atgcttggga aatcattaag
    12181 tctttaatag ctgcgccact actgtttatt atagatttaa ttactggtga cttcgaacaa
    12241 atgaaagagg atttagatct aatctggaac acacttgtcc aatcagtggt aaatatttgg
    12301 acatctgtaa aaaatatatt tacggaatat atcggtgcaa tagtaaatag tgccgttagt
    12361 ttatggactg gattcataca aagtatttct aatatttgga atgaagtagt ttatcaagcg
    12421 actatgattt ggattgattt gaaactattt tttactaatt tatggattga tattaaatac
    12481 agtgcaattc aaatgtggat aaatctaaaa ttctccataa ttcaaacttg gattgataca
    12541 aaatatggtg caattgaact ttggaataat ctaaaacaat ggtttttcca aacggttaat
    12601 aatatcgtgc aaactcttat aaaaagttgg aacagcttaa agcaaggaac gatagattta
    12661 ttcaacaata cagttcaagg tgctaaagac atttggactt cattcaaatc ttggattggt
    12721 gatttaatta ctggaaccaa agataacatc attcagggat gggaaaacct aaaacaaggt
    12781 actatagata ctttcaacaa tttagtaaat ggtgctcaag aggcatggga taatttagta
    12841 aatgctgtta gtgacacggt tgatagagta actggctggt ttgataactt gaaaaatatc
    12901 gatttactag cagccggaaa agctatcatg gatagttttc tagaagggtt acaaaatgca
    12961 tggaaatctg tgcaagattt tgttggaggt attggtgatt ggattcgtga acacaaagga
    13021 cctatccaat acgatagaaa gctattgatt ccagctggtc aggctattat gaacggtctg
    13081 aataaaggtc tgacaggagg attcaatgac gtacagaata ctgttggaag tatggcagac
    13141 tttatcgcgg aacttttcaa tgcaaattct gatgtagata tagctgcaaa tttgaaaaat
    13201 gcaaataaaa acattggtgc acaagttgaa cataaaataa atatgggtgg ctctactaaa
    13261 ccagctgtat ttaaaatcaa tcttggaaga caatcgttta gattgtttat ggacgatatt
    13321 tcacaagcta tgggcgaagg tgcagatatt aatctggaat tttaggaggg aatattttgg
    13381 atcaacgaga aaataaaatg tactcattca aagatacaac cattaatctc actagttcta
    13441 aacgattcct tccgacgtct gccatgatgt acgatggaat gtatttagaa gatttgattg
    13501 atggttatca aacacttacg gtggaaggta gagaaatgct ttctgtagaa gttgaacagc
    13561 aagagataca aattggttca atcattacaa atcagaaaat accttcaaga acactaaaaa
    13621 taacatataa gctggaagat agagatccag aaaaactaca gtttaaattc aaagaactgt
    13681 tgaattattt ataccggaat gaagacgtgg aaattaggtt tcatgatgaa ttagattatt
    13741 attactacgg tcgctataca tcaactgata ctgttccagg agactccaac tcgattattt
    13801 cgagttttaa tgtattctgt gcggatccac taaagtatac gaaagagtgt gttagtgatg
    13861 gctatattgg aaatccgata cagtttccta taacaccaag aaaaattgaa gttactttat
    13921 ccatgaataa ttcaatcaaa attacaaacg gagaacaaaa tatcacgata actgacgcgg
    13981 caataaaaac aggagacgtg ttggtttttg atttttccga tgagcaggta actgtaaacg
    14041 gagaagattg tacttctatg attgatttag aaagtgattt tgagaacttt tatcttaagc
    14101 aaggtcagaa gataactagc aataatggga agcttaaaat attctatagg ggggcgacaa
    14161 tttgagtgag acagtttatt tctttgatca cttgcaaaaa cttattaaaa gaaaaaatac
    14221 aagaagtttg attgaagtct cccaagaaaa agaaattagt tctgataaga gtgatctaat
    14281 gaaagatact ctttacgtta cgacaaaata tgataaagaa atagaggatg caagatatat
    14341 ggcgattcgt gaaaacgagt cgtctttttc gttgtatcga attactaaag ttagcgaccc
    14401 atttgaaaca ttagagttta cagggttagg atttgcgaca aatgaattag atgcttacat
    14461 catcaaagat attaggccga gtgggcagcc cttaaaaaat gttcttgatc gattgattga
    14521 atttactgaa ggaaattggc gcgttggtca cgtagaagca atgttaccaa cagtaactgc
    14581 aactttttac tatgtctctg taaaagaagc gttgaaagaa ttgcaaacct taggtatgga
    14641 atttgtcttt aggtgttctt tgaattctga tggaataaag gataaatgga tcgaagtata
    14701 tgaacaaatt ggcgaagaat cgaatacacg tttcgtatat ggtagtaaag cattaacagt
    14761 tgtaagagag atagatagaa gctcaatctc aacttcaatg ataggtcgtg ggcgaggcga
    14821 agaggttggt gacggttacg gtagaagaat tgaattcact gatgttgaat ggaaaaagtc
    14881 gaatggtgat cctttagata agcctaaagg ccaaaattgg cttgaagatc cggaatcaac
    14941 tcaaaagtat gggataccac aaaaagatgg atcaatgaga aaacgagaaa ccgtagtagt
    15001 gtttgatgat atagatgatc caacagattt acttaaaaat acttattcaa ccttaatcga
    15061 ttctgctaga ccgttagtac aattcaaagc tgaagtcact ggaggagatg tgataggaaa
    15121 tacagtgact attcacagat acgataaagg ttatcactat aaaactcgta tttataaaac
    15181 tacattcaat cggcttaccg gtcaaacgaa tatcgaacta ggggataatt taacacaaga
    15241 tgttagaaaa caaacggctt ctattgtcaa taatattaat agtttagaat ctagcaaaat
    15301 gacattttac gaatcgacag agattggaaa atatcaagat gacattatgc gaggtgcagg
    15361 agataatggc ggttctattt attgggtaaa tggaattgaa gctggtgtta gtgatagtag
    15421 agaaatctat gaaactgttt atatggatgg acctaacatt cctagatcac gcttttttat
    15481 ggtccaaaat aactcaggga tatctttcaa acaatgtaaa aaaggtgagt ggcaaacaat
    15541 tcaagatgta cacaatggtg atagcacgac cgcttggacg ttggatggaa ctttcaatgc
    15601 taattttatt cgcgcaggca ttctgtctgg tatcctcgtg caaggggtag ctttaaaaac
    15661 atttgacgat aaagatttcc aattagtggc agagggggga gaactttctt ttgaaaaaca
    15721 agtcaagtct actggactag atgatgtaca tggagaacgc ttgggctcaa ttgtatctac
    15781 ttatggttct aaagggatta acggctttgc tgtctggaaa gagccaaact atattttttc
    15841 cattaatgct ggggacggtg gcgatcgagg gaatcctatt tttcaaattc cagcagatgt
    15901 tactgctgat aagcgcaaat ataatcttta tggtgacggc aatttttcag aaggaaatat
    15961 aaccatagat ggacggctag atgtaaaaga actctatgtt aacggtacaa aaattgacac
    16021 taatggagga ggcaattccg gagggaacga taacggttgg aacggacaat acccaccaga
    16081 agtaactact gatcgggata aacgatattg gcaaatttgg gcaacggcaa taggtgccgg
    16141 ttttacacaa caagctgctg cagccttact tggaaatgca caaggagaat cagatgctaa
    16201 tccaaccgct gatgagggca atggcgcacc agggttcggt tatggtgtat ggcaatggac
    16261 cgattcttct ggcgcaacta gcggacgtgt ctacatgatc aatttaatga caaaggctgg
    16321 catcagtgat gatccagaca caatcacggc acagtttaaa ttgttgatgt ggcatgcacc
    16381 aaatggtcaa tggatcgcaa ctagcgctta tccttacaca tggacacaat tcatgaatct
    16441 gaccgatatc aacacagcag cacaagcatt cgtggctaac tttgaacgtc cacgtgatcc
    16501 acatccagaa cggacggcat ggtcacaaga atggtatgac aagttcaaag atttggaaat
    16561 tcctgtatca aaaggatata tgaagccgat tgcggatcca atcacagtga cgagcgaatt
    16621 tggctggcgc acttctccaa tcacaggagc acaagaattt cataacggta ttgaccttgt
    16681 aaatggaaat cctaatacac ctatttttgc ttcagcggat ggcgaagtga ttgttgcagg
    16741 tgatgcaaat tactttgact ggtatggaaa ttggacagtg attaaacacg ctgatggaat
    16801 gtatacagga tacgcgcatc aaagccgagt agacgtctca aaaggtcaga aggtaactgc
    16861 tggtcagcaa attggactga tggggacaac aggaccatcc actggagaac atcttcattt
    16921 tcaatttatg gatgagtttt atccatcttc ttcaggtcat ttccacaatg caagagacta
    16981 catcgatttc taaaggaggg atagtcatgg cagaaacgca gcataaaatg gtcctatcca
    17041 ccaccgaacc aaacaacgga ataaatttgg ttcgaattcg gcaaggggat gttttaacgc
    17101 aaaagttcgt tgttgaagtg gtggaacatg gcaaactaaa aacattcgag ggcctagtgc
    17161 cgttttttat taatacaaca aaatttggcg aaaaccaacc tgttgaacaa aaagtacaag
    17221 aatacagtcc agcgcaagca aggcttgttt acaccttaag tgagcctgac tggcaatggg
    17281 gtggtgaaaa caccgcacat ttcagtttcc gatcacttaa tggtgatgga acttggagtg
    17341 aacaatttag cacacaggat tttacctatc gagtcatttc tggaatatct agaagccagt
    17401 tacgtgactc tggctatgtg tggacatttg aggatttgct aagaaaattc aaagattaca
    17461 tggatcaggg caaaaatgac tgggagcagt ggttagaaga taatcgtgaa atactggaaa
    17521 atatcgatcc aggtggtatg atcattaaca ttctgaatga agctaaaggc gactacgaat
    17581 cattagctga tcgtttaaac caaaaatacc aagtgccagt cggcagctca caaattagag
    17641 aaacaacacg cttttttgat tacgacacga tgaaatacgt tgacctagtg ccgcgcaatt
    17701 tgaatacggt tgtcaacagt gttaataaca gcaaatttaa cttttctttc attacagaca
    17761 ttcacgcaga taatcacaac ttgcgtatag atggcgtcgg ttacaaagat gcttcttatt
    17821 taagacattg gcgcgcaatc cctcaatttc aaaaattagg gaacaaaaca gatgtgatga
    17881 tttacggcgg agacaatatc gacggcggac ttggttcact cggcagcgat ataggcatta
    17941 ttgatgaatg gagcgcgcga cattccatgt taggcacgct caaacgcttc actaacgcag
    18001 cggtagcagg acaagaaaaa ccggttatta tctgcaaagg gaatcacgac gcttgtttcg
    18061 accccgcgtg gcgcaagcga aagggaatgt tatgcaacgc tgacttcgaa gagtattgga
    18121 acggtttgta cggtggcgtg ttgttcccag ataaaaacgc agcaatttac cgtttcgata
    18181 cttgtgattt ttatgaaggc ggcacaggcg acaagtacgt ggacggttac agcgatacag
    18241 cgccgggagc tttcagtgcc aaacaaatta acgctttcgg agaatggtta gtgaacgttc
    18301 cgagaaacta tcatgtggcg ttagtaggac atacgccttt aggtctcagc aagtttcccg
    18361 ttcgcaatga aaacatgatt agcacgttga tagaagggtt taaatctggt agtccggtaa
    18421 ctatcgattg gtctaaatta ggacaaccga atgacggttc gttcggcgga ttaaagacct
    18481 tcgcaatgaa tacaaaaggc gccggcgttg tagtaggtta tttctgcggg cattggcacg
    18541 aacaagtcga aggggcgttt ggaacagtaa aaatgattct ttgcgacgtc ggcttctctc
    18601 atacagctag ccaagttgat acaccggatg aattagcgtt ttataaaata gaagttgaca
    18661 cagcaacaag aaaagtgaca agcaaaggcg tagggcgcgc gagagacttc acttataact
    18721 attaaggcgg tgaacaatta aatgttagat tttcaaagca aaccaaatat ttttgaagaa
    18781 atgagttatg aagaggctgt gaaatggtta ttgcgtcaag cggctatcca ttacgacggc
    18841 tcggatcacg acgcgcacgt cctagctact gaaagcaacg cgggctttgc tacaccggaa
    18901 acagttatgc aagcgcgtgg gcgttggtta cgcgattata agctaccaca aaaatatccg
    18961 aacattttag acattccgcc cggcaaatac gcaaccaaag ccggatgggg cgcagacaac
    19021 cctgacggga ttgaagatga cagttttgtt gaaatgatgg tattcgcgga tcacgattcg
    19081 agaaaattaa tcgtcgcttt tgctcgttat agcggcgaaa tttacatcaa aatgacacat
    19141 aacagcgaac cggtagaggg ttataactcg ttaggctggc ggcgcgttta cactacttct
    19201 gttctttttg aaggcgaatt aagaaaagga caatcagtca atctgccaga tgatactttc
    19261 cgttaccaaa cgcttcgtat ccactacaca gacggtgacg gagactttgt agaagaagtg
    19321 aaacgtcaaa gatacgcgcg aattacaaaa gcgaatttat ggaatggaga cgcgggagtg
    19381 acgttcatcg aatttgagct gacaatcgaa gcgcgaaaga taacgatgtc aaacggcaga
    19441 gctttagata tttcatccgg caatgtttcc aatcccgcaa tgagcaacaa cgtgaaaata
    19501 actaagattg aaggtgtgaa ataatggcgc atgtcatcaa aaaaggctct atcaaagtac
    19561 ctacacagcc gaaagactac gatttgcaag caacggggct tgtatttaaa tcatacgata
    19621 atcaaatagc gttagagttc aacgtcgaac aacagaacgg cacaccggcg gacttgctag
    19681 gagctaactt gcgcttgttg atgtttatct atgatgaagt agatggaatg atcacgaaag
    19741 agccaatccc ttttatcacg aaaaacctca tcactgaaag cttcttgaat ggacaggtcg
    19801 tatatatctt gccagaagcg atgaaagctt ataacggtat ggtggaagct tatgtttaca
    19861 tcgagtatcc agacggatca acaagtgata acttaggctt caccttccgt atgaagcgtt
    19921 cagcaatcga cggactagcg caagataaag cagactactt tattgcagac tttcaacaat
    19981 tacttgatgg agtcaaacaa gaagcaacag atgctgttaa cgcagcatta acaaatgtgg
    20041 attctacgat tgaaaaggca aaccaacaaa taaatgaatt tgtagaggga gccacacaag
    20101 caattgatca aactgttgac gaggtaacag agcaactaca agctactcaa actaagattg
    20161 ataccgtttc tcaaaacgtt acatcggcac aaaacaatct taaagcagtt gaagacaaga
    20221 tgaatcaaac caatcagcaa atcggcgacc tcggcaagct gaaaaagatg tacagtaaca
    20281 gcatcgactt cgggaattat gattatagtg ggaatccgaa tttaatgtcc aaactaaaat
    20341 cgagcgattt taacgttggt taccacgggt cactaacttc ggataacgaa aagctacatt
    20401 ttacttctga tggtacagga agcattatta tgtttacgcg tattaataca cctcagcttg
    20461 ctagtgggaa aacctatact ctgagtgcga aagttcgatt tgatgaagga actacaggag
    20521 ctattgataa attacgtttg gtgtatcgta catcaccagg agaaaagata ttattggaag
    20581 caaatagtac aaatattaca acagatgatg tagggaaaga aataacaatc aaaggtacag
    20641 ctaacgttaa ttatcaaatc acaaatttag atcgatttta tatgagtatt agctttgttg
    20701 acagggataa aataaatggc ggatttaagt tgtacgacat caaaat
//
LOCUS       DAFLWC010000055        19729 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.056, whole genome shotgun sequence.
ACCESSION   DAFLWC010000055 DAFLWC010000000
VERSION     DAFLWC010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19729
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.056"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            26..901
                     /locus_tag="L1V17_001812"
     CDS             26..901
                     /locus_tag="L1V17_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236578.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(1046..1198)
                     /locus_tag="L1V17_001813"
                     /pseudo
     CDS             complement(1046..1198)
                     /locus_tag="L1V17_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(1466..2797)
                     /locus_tag="L1V17_001814"
     CDS             complement(1466..2797)
                     /locus_tag="L1V17_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1236579.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(2946..3659)
                     /locus_tag="L1V17_001815"
     CDS             complement(2946..3659)
                     /locus_tag="L1V17_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1236580.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            3834..5258
                     /locus_tag="L1V17_001816"
     CDS             3834..5258
                     /locus_tag="L1V17_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBN1236581.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            5557..6264
                     /locus_tag="L1V17_001817"
     CDS             5557..6264
                     /locus_tag="L1V17_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBN1236582.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            6251..6574
                     /locus_tag="L1V17_001818"
     CDS             6251..6574
                     /locus_tag="L1V17_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBN1236583.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(6663..7700)
                     /locus_tag="L1V17_001819"
     CDS             complement(6663..7700)
                     /locus_tag="L1V17_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HBN1236584.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(8021..9004)
                     /locus_tag="L1V17_001820"
     CDS             complement(8021..9004)
                     /locus_tag="L1V17_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HBN1236585.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(9419..10189)
                     /locus_tag="L1V17_001821"
     CDS             complement(9419..10189)
                     /locus_tag="L1V17_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1236586.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(10182..11117)
                     /locus_tag="L1V17_001822"
     CDS             complement(10182..11117)
                     /locus_tag="L1V17_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1236587.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(11433..13082)
                     /locus_tag="L1V17_001823"
     CDS             complement(11433..13082)
                     /locus_tag="L1V17_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBN1236588.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(13199..15802)
                     /locus_tag="L1V17_001824"
     CDS             complement(13199..15802)
                     /locus_tag="L1V17_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBN1236589.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(15814..16863)
                     /locus_tag="L1V17_001825"
     CDS             complement(15814..16863)
                     /locus_tag="L1V17_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBN1236590.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(16889..17203)
                     /locus_tag="L1V17_001826"
     CDS             complement(16889..17203)
                     /locus_tag="L1V17_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBN1236591.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(17219..17665)
                     /locus_tag="L1V17_001827"
     CDS             complement(17219..17665)
                     /locus_tag="L1V17_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1236592.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(17666..19588)
                     /locus_tag="L1V17_001828"
     CDS             complement(17666..19588)
                     /locus_tag="L1V17_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBN1236593.1"
                     /translation="MGIEFSERQMKILYFLIENEHTTYKELSEQLYVSTKTISKDILI
                     LKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKINIADSPEDRLTYVFAKLLN
                     TNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLVSDRNGVRIKADEKSKRRL
                     MSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDILKKVAELLNRYMNKTQLK
                     FTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNTLILIKMIEKAFSIIVPID
                     EQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVRIKLNEFYPDEELINNLVL
                     HLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEEIEERFCIHFNEDEIAYVT
                     LHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFADMVEIEDVLSINELQDRK
                     VTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQLNEQTEDAFLNLLDKRFCF
                     FTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKLSSTAMNDFAMPHIEVDFI
                     KKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKIYETFNEIASNHELLANLK
                     TSSSFEKLVYILKEGL"
BASE COUNT         6016 a         3947 c         3216 g         6550 t
ORIGIN      
        1 aagtgtttca tgaaaggaga actagatgaa taattggctt gagtattttc ctgaaaacgt
       61 tttggaacgc ggttacagct atcatctgca cggttttgtc cgtcatttga actatacaag
      121 caagtacttg tccgcaacag tttctggcac ggaagattat aaggtagtga tcacttggga
      181 tgaaaagacc aacatgactt gtgattgtct atatgccata gaaggaaaaa aatgcaaaca
      241 catggctgct gtcttattcg cttacgaaga acgtccaata aaaaaatcca actactcact
      301 ttccgaactc tcgtcccttg tttcctccgc tagttcctct cttgtacggg agcttttaac
      361 agagattctt atagaacatc cgcaatttat cgaacgcttc aaagttaaga tgccatttca
      421 tgcaataaat tattcagata aattaacaac tatcatccat aaatacgatc atattatcaa
      481 gaaaaacaaa aacaggaaaa cagcgaagtt catcatggag atgcgaaagt tcatccaaga
      541 agcagttgaa tcgctcattc agcaaaatgc ctatcttccc gcattcgaat tgatcaatga
      601 agtgattgct actctcgaaa cattctattg ggagcctgag gatgaacgaa cccttcttct
      661 gatagaggac tgttattatt tatggaaaga attattagca gaagcacctc atgcagaaaa
      721 aaggcaaatg ttctcttggt tcgtctgcca agtcgatcat actgacgcct cttattcaaa
      781 acgctactcc ataaaaatcc tgaaagaaga ctttcgggaa aaagaatttt ctaaccaaaa
      841 gaaaaaaata gataaaaaaa ctaaagaaac ggtaaagaaa gacgatttca atgaaaaata
      901 gcaagtaaac gataacaacc atcctaaatc cacaagaaat acagcagacc ttgctttaaa
      961 aacacgaatc atgcaaagga tgaagtaaag aagacttaac gcgtacccaa tattagtcat
     1021 ttgactatta ggtacgcgtt ttgttttata agtcatgaca aatttccttc gttgctgggt
     1081 agattttccg gcattgttga tagattttat gatacttttc tacattttgt aagagaggtt
     1141 ccactgcatc tgtatattgg ataaaattct gacaacaact ttcaggtgtg tcgaaccact
     1201 ctaatcttta aagataaata ttaaaataac gattaataat attaacagtc tttatttttc
     1261 accaccaaaa acctatcttt gcatatacta aatagacgta tatacacaga taggtttgtc
     1321 ttgtgaaaaa taatgattat ccttaccaaa aaatgtttgt ttttctacat gttcgtactt
     1381 atcaaaaaat atgatcctta ttgaaattac tggctattta tattccaacg acttcttgtg
     1441 ttaatttttg ttatctcata gtaaattatg tttcattttc acttaattta gttgtcacgt
     1501 gttcgtcaat tcgtaaaaac ggtaaatata taaacacact tgcggctata attaatattt
     1561 gtaaaacagc tgctcgccag tctccggctg ttgctaaaaa tcccgatata actggtggcg
     1621 tagtccaagg aatttgcact actacatgat taattaatcc cacagcagtt gcaaaatatg
     1681 ctactgtcaa agaaaaaatc ggtgcaagca caaagggaat aatcagactg atattaaata
     1741 caataggcaa tccaaaaata ataggttcgc ttatattgaa tatagcggga gttaccgata
     1801 atttagcaaa gtccttataa tcttttctac gactgaagat aaatattgca atcaataaag
     1861 caatcgtatt tcccgatcca cccattaccg caaaggtatc tttaaaggcc atattgataa
     1921 tatgtggaat ttgctctttg tttgcataag ctgccatatt ttcttgcata ttctgaatca
     1981 aaaacggatc taacaatgaa cctgatatta ctgcttgatg gataccaaat ccaaaaaata
     2041 gattagcaat agatgtaatt aacaaaaatc ctggtaaacc agttgtaatt ttacttaatg
     2101 gctctgtaac tatcgtggta attagcttat ttatatccat attaaacaat tgaatgatta
     2161 taaatgacaa taaagcaaac gaggtaatcg taataatgat tgggattaat acattaaaag
     2221 actttaaaac agcgggagga atatttccgg atagctgaat ctgtagtttc ttattattag
     2281 aaagtttaat aaataattct gtagccgcta atccaacaaa tatacctaca aacattcctg
     2341 aagctcctgt ataggatata ggtatcacac ccgtcacttc aacagcttta tccgcatttt
     2401 caggagtaaa catcatctgc ataggtgtta atacaacaaa tgtcgaaata gcaactaata
     2461 ccgctgcaat atgatttgta taatttctgc ttgcacacat atgataagat actgctgcta
     2521 caactaataa tgtagttatg cttaatgtac cattggcaat tgaagtacca atttgttgta
     2581 acgtggtcaa tgtactagta tcgacaattt cccccatgaa tcctgttggt tctaagatca
     2641 ctgaattaat aagtgtcaca aatcctgcta acatcataaa tggcataaat gtagcaaacg
     2701 catctcgcaa agttcttaaa tggatctgat tccccaactt agtcgcaact ataccaaatt
     2761 tttcaaatac aatgtccttc ctgctacttt tgcccatatt ttttctcctt tatgcttatt
     2821 gtaatcgatt actttttcca cccaaataat acatcactta tcaaaaaaag taaatacttt
     2881 taattaaata tatatatctt ttttagtata aaaaaataag ctctgaaaaa ataattttcc
     2941 cgagcttatt tttcaacaaa aacagcttca aaaacaaagt cttgatataa atgtctcgat
     3001 accgaatact cgaaaggttt accagacgat agagcaacaa ctttgtctat ctcaatcata
     3061 aattcacctg gatctatttt taatattttt gcgtcaaatt cattcgcagt atctcctttg
     3121 atacgtatgt gcgaagtctt tatttccaga cccagttcat ttgtgatata agcatataca
     3181 gatttcttta aatgttttgg ttccaagcct ggtatgactg ctaatggcat gaatgtttgc
     3241 tcaatcgagt atggttgaca atcaataaaa cggcttcgta caatattata tacatagtct
     3301 tttacactga tacttaattt atcagctact tttttcgatg gaagttcaat tgagaaagta
     3361 tggatttctg aatctacgtg ttcttcacca accacgctaa acaaaccttc gtttggacca
     3421 agaactcgtg agttatcaat tggtgttctg acgacttcag tcccataccc acttctactt
     3481 cgcaaaactc cttcggaaac aagtaagtct acgcctttct ttactgttaa cttgcttgta
     3541 tgataaataa ctgccaattc atctcctgta ggaagtttct caccaatttt atactctcca
     3601 tttacaattt ttttctttat atctaagtaa atttccatat acttcgcaat ttttttcaat
     3661 ggtgaccctc caatcaaaaa catatcttca tctatacttt aacataaata aaccgataaa
     3721 atccacatca aaattataca cacaataaaa aagatatata tatttaaaca aaactattta
     3781 ctttaagttg taagcggtgt tatcattaag tggaaacagg aggtaaaaaa attatgacaa
     3841 ctatgaaaaa gctaactttt ccagatgatt tttggtgggg ttccgcttgg tcagctgagc
     3901 aagcagaagg aaaaggagaa acaggaaaag cagagactat ctgggatcgc tggtttaaag
     3961 aacaacctta ccggttttat caacgaatcg attcctctat tacaaccgat cacatccatc
     4021 aatataaaga agatatagaa ctaatgaaaa aaactgggca taactccttt cgcgtttcta
     4081 tttcttgggc acgaatgttt ccaaatggcg gtaccggaaa agtaaatccc aaagccattt
     4141 ctttctatcg aaaattattt tccgaaatga ataataacgg aatcaaagta tttgccaact
     4201 tatatcattt tgacatgcct gctactcttc aagataaagg aggatgggaa tcacgtgaag
     4261 tagttgatgc ttatgttcat tacgctgaaa cttgttttaa agaatttggt gacttagttt
     4321 gtcattggtt taccttcaat gaaccacttg ggcctatttt aggtacttat cttgaagatt
     4381 ttcattatcc aaacctcatt gactttaaac gcggagcgca agcagcattc ttcactatac
     4441 ttgcacacgc aaaagcaata caagtattta aagaactagc tcttcctagt aaaataggcg
     4501 ttattctaaa tttgagtcct acttttcctc gtagtcaaaa tcctgctgat gtgaaagcag
     4561 cagaaatcgc tgatttattt tatacgcgga gctttttaga tcctatggtt aaagggaatt
     4621 tttctaaaaa gcttatcctg ttattacaag aatataatca gcttcctgaa gattatacga
     4681 aagaagatct tgtatgtatc tacgaaaata ccgctcaaat tcttggacta aactattacg
     4741 agccacgtcg cgtcaaatct cgttcttcta tggtggatac atctagtcca tttttaccag
     4801 agtggttttt cgaaccacat atcatgcctg gacgacgaat gaacgaatac cggggatggg
     4861 aaatttacga aaaaggaatt tatgatttgt gcatggatat caagaaccat tatggaaaca
     4921 tcgaagcatt tatctcggag aacggaatgg gcgttgcgga tgaagaacgt ttcatggatg
     4981 atacagggca aataattgat gattatcgga ttgagtatat caaagatcat cttgcttact
     5041 tatggaaggc aataaatgaa ggatgtaaca ttaaggggta tcatctttgg acatttattg
     5101 attgctggtc atggatcaac gcctataaaa accgatatgg gctggtttca ctcgacctta
     5161 ctactcaaaa aagaacaatt aaaaaaagtg gcgaatttta caagcaatta agtgatacaa
     5221 atggatttag atacgatgta gacttgttag ttgaataata ttctaaaatt ccacttgaag
     5281 tgaacacatt agaaaacaag aataatgaga aataccaata acaaatactt tttcttcata
     5341 cttcatttat acttgtcagt ataagagact gtgacaaatg tagtgatcct cagaagttag
     5401 gtctggaaat ctaacttgag aagatttttt taaactacgt ccagtctttt ttatttgttt
     5461 aaaattgaag ttgacaagtc ttcattaaaa atttagaata ttcacaagtt tgacgacaat
     5521 tatgaaaatt tatgtcgtgc taaaggagtt ttgttattgg atgaaaagtt agatataaaa
     5581 actgcgatca aagacacgtt acctaccgtt tttggttata tcggtattgg acttgcattt
     5641 ggtatcgttg ggaaagctgc cgggtttcat ccgctggtcg tcacgttgat gtccctgctg
     5701 atctatgctg gttctgccca atttatcacg gtcagcatgc ttgctagcca tagtccactg
     5761 ctctccatcg ttctctcgac ctttctagtc aattcccgaa tgattctgat gagtatgacg
     5821 attgctcctt atttcaagaa aaatcggctg cttcaaaatc tgctgattgg cacattgctg
     5881 acagatgaaa gtttcgcact gggaatgaat aaattgaact atactggaca aaagttaaac
     5941 tttcgttgga tgaatacagc taattggatt tcttatttga cgtgggtggg ttcttctctt
     6001 gttggcgcac ttttagggaa ttttattact gatccgaaaa agtttggttt ggatttcgcc
     6061 atcgtcgcta tgtttatcgg gttactttat cttcaagtca tttctgatag aaacacctct
     6121 aaacgattac agttgatcct gattggtctc actttgattc tggtatatgt cggactgatt
     6181 tttatcccaa gtaacttagt gattttagtt gtaacactga ttgggtgcgg attgggggtg
     6241 tggatcaaac atgccttctt ttgagtttac attgctgact attttaggtt gtactttagc
     6301 aacttggctt tctaggatcc taccatttgt cttactgaaa aaattcgatt tgccgcaacc
     6361 gttgcttgag tatttaagtt ttgtcccgat cgtcattatg tctgctttat ggttcagcag
     6421 tctatttacc caaaatatcg gacatctgcc gcagatcaat ctcgaaaatg ctttggcttc
     6481 agttcctaca cttttagctg ctattctttc aaaaagctta ttggtgatcg tcttggtagg
     6541 aattctttcc ctttcgttga ttcgcttatt ataaataaaa aaacaagagc ttatggcaaa
     6601 ttactgtcat gcgctcttgt ttttatcaaa gtcaaataag aaaaaaatcg gcgtattctt
     6661 gcttatccgt tgaacggacc actaacaacg acttttccta atatatgtcc tgtttctacg
     6721 tctttggttg cttgtttcaa gttcttcgca ttcatcccat ctgaatagac cttgctcaat
     6781 gtactgcgga taatcccttc atttgctaaa gcagcaatgt gcgctaaagc ttctccttgc
     6841 gtttcgattt catagttata gtctgtttta gcgaacatat actcccagtc gaagctgata
     6901 gattggtttt tccaaacacc tatatctaac ggctctttga tccctacgat cgttcccaca
     6961 tgtccaaatg gtcggacaag gtgtttgatt tgatcaaagt agcgggtaat atcgaataat
     7021 acagcgacat actctacttg atcgattcct aattcacgaa aacttttact taagtcgtga
     7081 tgataatcga ttggatagtc tacacctgtt tttttcagcc attcaaaatt cttcggactt
     7141 gcagtcgcgt agacttctag gccagcccaa tgcgctagtt gattcaaaat cgaaccgacg
     7201 cccccagctc cgttgatcac taagattttt ttcccgcggt tggcattttc ttctggagtc
     7261 agaccaaatt tttcaaataa caattcataa gcggtcaatg aggtcaacgg caaggctgcg
     7321 gcttcttcat ctgaaagatt ttttggtgca agagcgacaa tacgttcgtc aaccagttgg
     7381 tattcttgat tgcttcctgc tcttgtcgtt gtacctgcgt aaaaaacgcg atcgccgaca
     7441 gaaaattttt gcacttcatc acctacagca acaactttcc cgactccatc aaaccctaag
     7501 atacgtaaag catttcttat cccgttatct tggcgaagtt tcgtatcgac aggattaaca
     7561 gatactgcgt tgacttttac cagaagatcc cgtgaactgg gtacaggtat ctgttctttt
     7621 tcatcaataa agctttttgg atcatcgatc gacaaccctt cataaaaacc gactaccttc
     7681 attaattcct tttctgacat acgaattcct ccttagcttc atcaagttgg agcatccata
     7741 cagttttcat ttcaatatat atagtatgct atttgttcca cttttattca tcataattat
     7801 tctcttactt aaagtaaact atttgcactt ttttggttaa aaaagaggtt gcgacaagac
     7861 ttttgtcaca acctctttta aacggtgttc aatcaactga ccctcggtat tcgctcaaaa
     7921 aacgacaaaa tatgaggagc tatttttgtt tggctgttct tattacttga tgcaggacag
     7981 ctttttcacg acctctaatt cacggtgttc aagcaagaaa tcattgttca ctgaaaagcg
     8041 ttggatgttc tttttcaaag gtgtctaaga tctctcgtac ttcatcagta gatttcgtat
     8101 tcatcaactg aactcgcaag tcatttgctc ctggaaatcc tttgatatag attttaaaga
     8161 aacgatgtag tcctgtgatg gaacgcggga tgatttctga ataatgatct tgcagatcta
     8221 gttgcagacg aagtagtccg atcagttctt tttctgtatg ttccctcggt tctttttcaa
     8281 atgcataagg attcttgaaa atcccccggc caatcatgat gccatctacg ccatattttt
     8341 cggccaattc ttctcctgtc tggcgatctg ggatatctcc gttgatcgtg atcagtgttt
     8401 gcggagcgat ttggtcacgt aaagcaatga ttttagggat gacttcccaa tgtgcatcta
     8461 ctttactcat ctctttacgc gtacgcaaat ggacagaaag attggctata tcttgatgaa
     8521 gtaggtgact gatccattct tccatctcag acatttccgt atagccgata cgcgtcttga
     8581 cgctgacagg caaaccgcca gctttagccg cttcaatcaa ttgtgccgct acttctgggc
     8641 gaaggatcaa gccactgcct tttccacgtt ctgctacatt agggactggg cagcccatgt
     8701 tgatatcgat tccttggaag cccatttctg ccatagcaat gctcatttct ctaaaaaatt
     8761 ctggcttgtc tccccaaata tgggcaacca tcggctgttc atcttctgta aaggtcaatc
     8821 ttcctcgtac actgtctttt ccatctggat gacagaaact gtctgagttt gtaaactcag
     8881 taaagaagac atccggtgct gctgcatgct ttacgacatg gcgaaataca acatctgtta
     8941 catcttccat tggtgctaaa acaaaaaaag gctttggcag ctctttccaa aaattagtag
     9001 tcatttattt gttactctcc attctatcaa gcagtgaagt cgcaatcttt ctcaaaaaca
     9061 ttgtcattat actaggaaac aaaaaaagaa gcaaagtgaa cagcttaaaa gatgtttctg
     9121 attgagcaaa aaaagactgt gacaaaaatc ttatcacaat tccttttccg gaataaatgg
     9181 tgttcaaaag cttgcatctg cggtaataag tccaaccaaa cgaaaaatag gaggagctat
     9241 ttttgtttgg ctgttcttat tacttgatgc agaacagctt tttcacaacc tctccactaa
     9301 acggtgttca atcagctgac cctcggtatt agctcaacaa acgacaaaat atgaggaact
     9361 attttcccgt ttgtttctct aatactcagg tcaaaacgct gatttcacaa cctcttttct
     9421 aacttctcaa tcctcttcct ttattgatca aataccaagt aacggcgtac aaaacaacga
     9481 tgaatagcac aagtacgatc atcgatgttg ctactggcac atcgattgtt ccaaggaatc
     9541 cgtaacggaa accggagatc atataaacga tcggattgac tttcgaaaca gcttgccaaa
     9601 atggcggcaa catagagatg gcatagaaaa cgccacctag ataagttaac ggctgcaaga
     9661 caaatgtagg cacgatcgat acatcgtcat aagactgagc aaaaatcccg ttgagcagtc
     9721 ctgctaacga aaacaagatt gccgtcatca ataatgtaat gatgaccatg aaccatgaat
     9781 acacatgaag tggtacaaag aacaaggaaa tgatcgttac gagagagccg acgagaatac
     9841 tgcgacccac tccgccaatc acaaagcccc aaatgatcac atgcgtagga acaggcgcta
     9901 ccaagatttc ttcgatgttt ttctggaatt tttgagagaa gaaggacgaa gaaacgttgg
     9961 catacgaact agtgatagca gacatcataa tcaaaccagg cacgatgaat tccatatatg
    10021 aaaaaccacc catgtcaccg atccgaccac cgatcatttt tccgaaaata acaaagtaca
    10081 aggatgtcgt gatcacaggc ggaaccagtg tttggaccca gatacgcaaa tagcggttcg
    10141 tttccttgat agctaaactt tttaatgcag taaaataaag attaaacatt tttctcctcc
    10201 gtatgattat tttcttctgt gattttcaaa aacagttctt ctaaacgatt cgacttattc
    10261 ctcatagaaa gaactttgat tccttgtctt gtcagctgat cgaagattcc gttcacccct
    10321 tgatttcgtt caacttcgac agcgattgtc tgttcatctt caaatgtaca agcgtatcct
    10381 tcaatcacag gtttggtctc atatggcgct aaatcaaaga taaatgtttc aaattgcagt
    10441 ttggatagaa gctctttcat actagtattc tcgatcagtt cacctgattg gatgatcccg
    10501 atgttgcgac aaagcatttc agcttcttct aaataatgcg tcgtcaaaat gatcgttgta
    10561 ccattttcgt tcaattctcg gagaaactcc cacatctcgc gtctcaattc aatatcgact
    10621 cctgctgttg gttcatccaa gatcagcaaa cgtggttcat gcatcaatgc cctagcaatc
    10681 atcagtcttc gcttcattcc cccggaaagc atacgtgcac ggacatttct cttttcccaa
    10741 agattggact gcttcaaata tttttcgctg cgtttcatcg cttctttgcg agagacaccg
    10801 tagtagcctg cttgattcac gacgatttgc tggaccgttt caaagggatt gaaattgaac
    10861 tcttgcggga ctaatccaat ctgttgcttt gctcggacta gatccgtatc cagatcataa
    10921 ccgaagacat tcacttttcc agatgtttta ttgactaaag aagtaatgat tccgatcgtt
    10981 gtagacttcc cagctccatt tggtcctaat agcgcataga aatctccttc tttcacggaa
    11041 agatcgattc ctcgcaatgc ttcgacccca cttccataaa cctttttcaa attatttatt
    11101 tcaagcgcat ttgccattta tttcctatct ccttatagac atgattcttt attgtatcat
    11161 ggaatacagc agatgaaaaa acaacttggt tccagcgaaa aatcaggttg ctgggctcag
    11221 gaaaatctcc taatgaaaga catcaatcgg acgaagtcag acaacctttt cagaaaaaac
    11281 aaatcgaaga taaaggatta ctattcatat gtgcaacaaa aggagcgtga gacaaaagta
    11341 aagaacactt ttgtctcacg ctctaaacac gtataaacgg cggaagcaaa agccaagatt
    11401 tttgatccaa taaatacttt cgatcacttc gcctatccca atacatgcca ctgccgcttt
    11461 tcatcaaata acgcggcttc cgtttttgcg gtttctacta aagtctctgg gtaatccaaa
    11521 actttcagca aggcaatcgc atttcgggtc cttgaaggtc cttcttttaa tttgaaatca
    11581 aaactgattc cttttccttc tgttacttgt tcttcaaagt ggacattctc acaataattc
    11641 tttaaaatct ctgtcaattc gatatcatgt gtggcgacaa atgctaaaga tggatactcc
    11701 gcaagccacc gaacgactga agcggaagaa gcaatccgtt cgatcgtatt tgtccctttt
    11761 aaaatctcat ctacgaagca gtagcagcgt tctttggaag ccacttggtc caacaaacgt
    11821 ttgatcgatt tgatttctga aacaaaataa ctgtcgcctt caaataaatc atcttcgatt
    11881 gccatggaag tcaacacatg tccaggttgc agggtaaact gttctgcaat cgctgtttgg
    11941 atcgtctgtg ctagaataca gctgatggct atacttttga catacgtaga ttttcctgat
    12001 gcattggaac ccgtgactaa tgtattcttc tgccagttga ccggattcac taccgcttct
    12061 tttaacaatg gatgatagat atctttcgct gtcacaccgc cctcagtaaa ctctggtcgg
    12121 caagtgatgg gcatataagt acggtaattc aatattgcag cggctacttc taattctccc
    12181 agcaattccc acagcttgat ggcttcagtt gaatgctttt ctaatttagt gagaacgaaa
    12241 tgataggaga taaatggcag catgaacatg atgttgacat attcaaaaat caactctgct
    12301 tcactcccac tcttcatacg aaatgaaaaa cctaatttag ggatgtctct taatggttta
    12361 gtttgctgtt tcagctcttc ttgaagtggt gtcggcagtt ttgctagctg attggcggct
    12421 gaaatcgttg aaaccaaata actcatgcta ttcagctctg tttctagtgt ttgtttcttc
    12481 actagataat agaccgtatt gaatactaac ccaccgattg ccaaatagat tcctagtact
    12541 tgtcctaaaa gaagcaaacc caaacccacc agcggaagca agccaagaaa aataaataaa
    12601 cctacgcgtc caatcttttt actttttcca tccgctagat attgttttgc aaaattatga
    12661 tctttttttc ctaaacgagc gaattgatat tggatttttt ctctcagttg aggattttcc
    12721 tgataaaaag caatcagttt ttctaactgc tgatcttcac caaaatcaaa gctgcgtaaa
    12781 cgttgataca acgcttctga acctacacta gaataggtac tgttgattcc ttcgaatact
    12841 tcgaacatat ccaggtcata ccaagtaaga tcatcgattt cgctatccca tgaacggaac
    12901 ttcttctccg tgagccatgc ttccttcaag ctttcttctt tatcaaatct cggttgataa
    12961 ggaatttttt cccatttgct acgaactgtt tcctttaatt tcaaacgtga aaaaatgtct
    13021 aaagcaacta ataaaataac agctgcaata ataattaaaa cgataaattc tctttgaccc
    13081 atatccctct ccgttccttt atttgttagc tttagtatag cactgttgcg ctatttgaaa
    13141 agagggtaaa aaaacacctt tcaaaataaa aggtgttttt ttcttgtata ttacatattt
    13201 atctctcatt tatcaaaatt gacaaataat catagggagg aattgttgtt aattcttgtt
    13261 tattctccag tgcattgaca actgtcccaa gggaaaggat agcctcaggt actatttttt
    13321 cttgttctgt tggattagct aagcgaagaa caaatccttg ttcatgaaaa taagaaggat
    13381 aaatcgatga tacaattaag tcttcaggta attcaatcaa tgaaaattta cgaggaacat
    13441 caagttcatt ttgtaatggc caaatcttgt tatctaacct gtgaataaat acattcagtt
    13501 tctgcttttg ataagaaata gattgttcta accgtttttc tgcctgtttt gccactttga
    13561 actcattaaa tcttccttct tctacattaa atccaaaagt gactttatac tcacctatct
    13621 cttgagctag cggtgtttcc atcatgacat gcccttcatt tgtcgtatct cctgaagctc
    13681 gcccaggtcg ccaagcaaga ttaggttttc caagttcccc tgttgttgaa aataaggtta
    13741 tgattaattg attttctata cgttcatact cttttaaacc atctgcataa aacgtaaaat
    13801 aatgatcatt ttctgccaca gagacactct tatcgaatat ttctaaatta acaggtttct
    13861 ctaccatagt ttctgaccaa ttcggaggaa tgacatcagg ggtattttca ataaatccgt
    13921 tttgaatttg tgcaattgat ttttcagatt tatctaaaac attaattgct aagcgcatac
    13981 gatgcgagta aacagtatta tgaattttga gtgtgccttc aacgatttga ctttctccca
    14041 gactgaacga tatttcataa gatatttctt ccatttcggg tttttcagat aaacgatctt
    14101 ttaaatcttt aggaagttga gcttttccgt aaacaactaa tgtttcttgt aaagaatctt
    14161 tatatacttt agctgtttct aattttagag atagttctgt atctccttct aatggtgaat
    14221 aatcatacgt atcgccatca tttgctgaat cgatcaaatg aacgaaatca agatattgtc
    14281 tatctccaac tatcaaattc aattgcccat ctttaaaaga aagtttatat ttattgttac
    14341 ttatctcagt tttgtctatc tcgattgctg tttctaattt ttcattattt ttctcaaatt
    14401 caacaacagt gtatcctagt gctggcacat ttacatttat ttttatgtca agttcataat
    14461 aagctggttc atcaaaatat tcgaaacctg tagcaatcat ccgataagca tttttccgtt
    14521 ctggaaaata aacttctttt tcaatgatat tatagggact acctttgaag tgtattttct
    14581 ttgaatcagc tactacatgc acgattttcg atccactata attctcagtc gttgtgttga
    14641 aaacaaggac ttcattcgat tttagcttta atgcatcagc catccgtttt acaataaggt
    14701 tttcgattcc gtcagctatc tcattagctt ctttgattcg atggaaaata tcttccgcaa
    14761 cattatctga aacacagcca ccaatactat catgagcctg gttttgcaaa atctttttcc
    14821 ataaccgacg aagtaggcct ttactgatat ggataccatt tctttctgca atcagcatga
    14881 gcggctcaac tcgttttaga attttttgtt ccaatttaaa attttctatt ttcatttttg
    14941 ttcttactga gccaatagaa cgatgaacac gagagtaaac cggctgacga agttcacctt
    15001 tatattcagg taattctttt ttgtttctga taacttctac ataagaagga taatctgaaa
    15061 taatattgtg gaatttactg tatttattca acttctctac gacttgatca aaatttaaaa
    15121 tcattgactt ttgatctaca cccgaaggta ctaaaatatc tttgtttttt ccttgcatat
    15181 gaagcatttc aactgcttca tccaactttt cttttgcaaa ttcaggaata tctttaattg
    15241 cgtctaaggt catcattcca gtcatataac caaatggaaa attcatggca taaacaaatt
    15301 tatctcccaa tcctttccag ataaaataag gagatggaac catcgtttca aagtttaatc
    15361 ctcgccaaca catgaaatta tcgatttcta cttgatgcaa aagtgtaggc aaattcgcat
    15421 tgaacccaaa cgtgtcaggc aaatacccta ccatcattgg atctccatat ttaaggatcg
    15481 tatcactgat tccaatcatt aagtttctta aaattgattc agcatccact aataaggcat
    15541 ctgtttgtgc ataccacggt cccacgaata gttgtcctgt tttcatcagt cgttggataa
    15601 ccttaagctt ttgcggattg atctccaaat actcatcgac gattgaagtt tgtccatcta
    15661 aacaaaagtt tactttaggg ttcctttcca attcatctag aacttcagta aagacctgat
    15721 cagacaatac gatggcatct tcatttgtaa aataccattc tctgtcccag tgcgtgtgtt
    15781 gaattatatg tgcatttacc atatcagatt ctcctacttt ccttcttcta ctgaatttac
    15841 ttgttgttct tttttatact tgatggattt tagtgcattg accattaacg ctgtaaccac
    15901 tcccccaata acaattgata ctaaatataa aggtatattc gtaacaaaag gaattgccat
    15961 aaaggttgaa agcattgttt cttgagtaac accaaaaaat ccatttagac cacatgctac
    16021 tgcagtgccc accacgatgc ttggtattac tcgtaaagga tctttcacgg caaacgggat
    16081 cgtcccttca gtaatcccca caaggcccat aatcatagct gtctttgcat tatctcgttc
    16141 cgattcatca taaagttttt tgtttaaaat tgttgctaaa aacattccaa atggcggaat
    16201 agcaattcct aataacatgg ctgtactagg tccaaagctt ccgcttgaaa aagaagcaac
    16261 cccaaaagca tatgcgattt tattgatagg tcctcccata tcaaacgcca tcattcctcc
    16321 taaaatagcc gacatcaaag cagcatttgc tcctgacatg ccttctagcc aattagtcag
    16381 tcctgttgtc attgcttgaa taggcgtagc tagtacatac cataatatga ttccaacaac
    16441 taatgtagta acaaaaggaa tcagcataat tgattttaga ctaataactt gcatcggtac
    16501 ttttactttt ttcaatgcat tagctaaata gccacaagct aatccagcaa ccattcctcc
    16561 aataaatccc ataccaagat tttgacacat catcccagtg ataaaagctg gtgctagacc
    16621 gggacggtca gcaattgaat atgcgatata ggctgaaatc atcggtacga taaactgtaa
    16681 tcccgtctga ccaatcattc gcaggactcc ccagaatgta tccgtctggt cccaaacacc
    16741 tgtgccacca aaaatgactg caatagaagt tagtaaccct gctgctacga caagcgggat
    16801 catataggaa accccacttt ggaaatgatt tagaatttct cttccttgtt tcttgaattc
    16861 cattagtaac tcccccacga tatatttttt atttgttaat taatgcaatt gcttcatcaa
    16921 tcgtctcttc accatctttt actacctctg aggtccctac tgttaaaatc ggtttaccgt
    16981 caaagcgacc tcgttctgaa acatttgtat ctactgcaaa tatgacaaca tctgcctcgg
    17041 aaacatccga aattgaaagt ttgttttcta tccccatagc cccctgtgtt tctactttaa
    17101 tatctaaccc tttcttcttc gcaaactttt ctaaattagc ttttgccata taagtatggg
    17161 caatccctgc gatacatgct gttactgcta ctatttttgt catatgaaat tcctcctttt
    17221 aaaatgatag agcttttacc aattcttttt tatttctcga atcttttatt cttttaacaa
    17281 actcgtcatc catcaatctt ccagataatt ctgctaaaat acgtaaatga ttagtacctt
    17341 tatcagtgtc ttttattgct aacaaaaaga cgagatcaac tggttgatca tctaatgcgc
    17401 cccattcaac agaccgcttt aacttggcta cagccactgt tgattcaatt actgctaggc
    17461 ttttgccatg aggaatggcg atatttttcc caattcctgt ggtcatatgg ttttctctgt
    17521 caaatacgtc tttttgaaat tgtttgtggt cagacacaaa cccattagtc tctaacaatt
    17581 tcgataattt ttcgactaca ctttttttat cagatgcatt taaatctatc actatattat
    17641 ttatattgat tttttcactg atcatttata agccttcttt caatatataa actaattttt
    17701 caaacgacga actcgttttt aaatttgcta ataactcatg attcgaagcg atttcattga
    17761 atgtttcata aattttattc aattcaggtt ttactttttc attaagtgca aaaaagaaaa
    17821 cagaatgaac aagtgtccca tcccaatcaa ttccttctgg attaacgtag acacagatta
    17881 ctggcttttt tataaaatct acttcgatat gcggcatagc aaaatcattc atcgctgttg
    17941 aagatagttt ttctcttttg attgctccct ctagtatccc ttctttcgcg taattttctt
    18001 ttaccaattt tttggtaatt atatttaaaa cgttcacttg attatccttt atttggtggg
    18061 taaaaaagca aaatcgttta tctaataaat ttagaaaagc atcttctgtt tgttcattta
    18121 actgtagata ctgttttact tttctgacat ctgcccctaa catcaaagga ctaacaacaa
    18181 taacaggaaa atttgtattt tcaatcggaa tcgtgcttat aacaagttca tcagtgactt
    18241 ttctatcttg tagttcattg atgcttagta catcttctat ctcaaccata tctgcaaaac
    18301 cgttatttat tctttgctct aataattttg atgttccata tccgctacta caaactaata
    18361 tcactttcgt tttgtcaggt ttgtaacgat ccaaaagtga ttgaatatgg agtgttacgt
    18421 aagcgatttc atcttcatta aaatgtatac agaatctctc ttcgatttcc tctaataaat
    18481 ctacacttat cataaatgac cttttaaaag aatatttgat tttgtccgta taagggttat
    18541 agatatttac tcccaatttg agtcttttaa ctgctgcatt gagatgtaat actagattat
    18601 tgatcaattc ttcatcagga taaaattcat ttaatttaat tcttactaac tcttgtagct
    18661 caacacccat atctaaatag gaaagcttcg tttgatctaa gtcgtgattc atagcatttt
    18721 tttcaatcga agtaatgtga atgtcaacat aagcttgttc atctattggc acaataattg
    18781 aaaatgcttt ttcaatcatt ttgattaaaa taagtgtatt ctttgagatt tcttcttcag
    18841 aattattact acgtgataag aaattgcttg tttcaatcct ttctatcgca atagcaaggt
    18901 ggatagctaa agtttgaaat tcataatctg taaatttcaa ttgtgtctta ttcatgtatc
    18961 gattaagcaa ttcggctact tttttcaata tgtccttatt taagaaatta ttcgcttcac
    19021 caatgaaatt gatattcaag tctaagagat ctgttttact gttagatgct gtaaagccac
    19081 cccaataata gttcacaact tctgacatca accttctttt acttttttca tcagctttga
    19141 tgcgcacgcc atttcgatct gaaactaagg acatcccatg cttgtttagt ctttttctaa
    19201 catctttcat tgtgctttct accgtcgacc tgctcacgta taattcgtca gcaagatttt
    19261 gaatctttag agaatcatta gtattcaata atttagcaaa cacataagtt agacggtcct
    19321 ccggagagtc tgcgatattg attttatgac tggataataa atttcgaagt gtttcttttt
    19381 ttccaataag cgaaacgcct tttttaggtt gaaccaacat ttgtacatct ggcatttttt
    19441 ggattatttc tttcaaaatt aaaatatctt tgctaattgt tttcgtagat acatataatt
    19501 gttctgataa ttctttgtaa gttgtgtgct cattttcaat caaaaagtat agtattttca
    19561 tttgccgttc gctaaattcg atgcccatta tcttcacctc ctgaatacag cttaagtgta
    19621 caattattat ctctattttc atacagaaga aagttcttga ttaatgtaga agtttctaat
    19681 attcttgatt atttcaaatc aataaaaaag cctgcaatat ttatatcac
//
LOCUS       DAFLWC010000056        19633 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.057, whole genome shotgun sequence.
ACCESSION   DAFLWC010000056 DAFLWC010000000
VERSION     DAFLWC010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19633
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.057"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(459..1088)
                     /gene="udk"
                     /locus_tag="L1V17_001829"
     CDS             complement(459..1088)
                     /gene="udk"
                     /locus_tag="L1V17_001829"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HBN1236594.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1172..1867)
                     /locus_tag="L1V17_001830"
     CDS             complement(1172..1867)
                     /locus_tag="L1V17_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBN1236595.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1880..2596)
                     /locus_tag="L1V17_001831"
     CDS             complement(1880..2596)
                     /locus_tag="L1V17_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HBN1236596.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2926..3534
                     /locus_tag="L1V17_001832"
     CDS             2926..3534
                     /locus_tag="L1V17_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HBN1236597.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            3859..4182
                     /locus_tag="L1V17_001833"
     CDS             3859..4182
                     /locus_tag="L1V17_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBN1236598.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4364..5734
                     /locus_tag="L1V17_001834"
     CDS             4364..5734
                     /locus_tag="L1V17_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBN1236599.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5864..7165)
                     /locus_tag="L1V17_001835"
     CDS             complement(5864..7165)
                     /locus_tag="L1V17_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBN1236600.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(7519..9477)
                     /locus_tag="L1V17_001836"
     CDS             complement(7519..9477)
                     /locus_tag="L1V17_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HBN1236601.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9654..9920)
                     /locus_tag="L1V17_001837"
     CDS             complement(9654..9920)
                     /locus_tag="L1V17_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBN1236602.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10430..12556)
                     /gene="pnp"
                     /locus_tag="L1V17_001838"
     CDS             complement(10430..12556)
                     /gene="pnp"
                     /locus_tag="L1V17_001838"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBN1236603.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12744..13013)
                     /gene="rpsO"
                     /locus_tag="L1V17_001839"
     CDS             complement(12744..13013)
                     /gene="rpsO"
                     /locus_tag="L1V17_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBN1236604.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13264..13827
                     /locus_tag="L1V17_001840"
     CDS             13264..13827
                     /locus_tag="L1V17_001840"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBN1236605.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(14080..14601)
                     /locus_tag="L1V17_001841"
     CDS             complement(14080..14601)
                     /locus_tag="L1V17_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBN1236606.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14604..15446)
                     /locus_tag="L1V17_001842"
     CDS             complement(14604..15446)
                     /locus_tag="L1V17_001842"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HBN1236607.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15439..16164)
                     /locus_tag="L1V17_001843"
     CDS             complement(15439..16164)
                     /locus_tag="L1V17_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBN1236608.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16340..16636
                     /locus_tag="L1V17_001844"
     CDS             16340..16636
                     /locus_tag="L1V17_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236609.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17204..18796
                     /locus_tag="L1V17_001845"
     CDS             17204..18796
                     /locus_tag="L1V17_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBN1236610.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18809..19549
                     /locus_tag="L1V17_001846"
     CDS             18809..19549
                     /locus_tag="L1V17_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBN1236611.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
BASE COUNT         5620 a         4028 c         3724 g         6261 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaac agttggctgg tgactgttca aaaagcagaa tccttgcttt
      421 tcaaacggtc gcagtccgtt caactgtttc gctgcgcact atttatggtt taagaaacta
      481 gctacttttg ttgtaatcaa atcaatagca acgtggtttt ctccgccttc tggaacaatg
      541 atatccgcat agcgcttcgt tggttcgata aattgatgat acatcggttt aacaactgtc
      601 aaatattgtt cgatcacgga gtccaatgtg cgtccccgtt cttccatatc ccgtttgata
      661 cgacgaatga tacgaatgtc atcatctgta tctacgtata ctttgatatc catcaagtca
      721 cgcagacgtt cgtcttctaa aatcaggatt ccttctagaa tgatcacttc ttttggttcc
      781 tgaatgatcg ttgcctgact tcttgtatgc gctacatagt catacacggg tttttcaatg
      841 gctttatagt tcagtaagtc gcctacatgc tgaatcagca gatcattatc aaaggcaaat
      901 gggtgatcgt aatttgtgtt caatcgttct tcaaaactca aatggctctg atccttgtaa
      961 taagaatctt gttcaagcat catgatggaa tggtccggga agttgttgaa aatcgcacgg
     1021 ctgacacttg tctttccgct tccggatcca cccgtcacac caatgataat tggcttgctt
     1081 tttgtcattg actaaaacct ctttcgtatc cgttttttca ttctaatcta ttatagcgaa
     1141 aaaacacgaa aatgctatat ttttctgaaa attaatcctt ttcaatttcc aataatgaat
     1201 aaagttcctc taatgaatcg attcgataag taggctggat ttcttcgatt tctggtaatt
     1261 tatttctatt gaaccaaatc gtatcgatcc ctgccatatt tcctcctttg atatcagaag
     1321 tcaaagaatc accaatgatc acagtttgct ttttatcaaa attaggaatg tgggaaaaga
     1381 catgatcaaa aaattctttc atcggctttt gcgctccgac agcttctgag acaaagatat
     1441 ccttgaagta atcaagcatt cctgcatctg ttaatcgccg atgttgcgtg tgcgacacac
     1501 cgttcgtcac aatataaaga tcagcatgcg gatggacctt tttcaggatt tctagacttc
     1561 ctggaacaag atcatgacct tggttcaagt agtggcggta gcgtttttcc atttgatcac
     1621 tatctactgt tttcccaaat tgctggaaaa gtaacccaaa acgactgcct attatttctt
     1681 ctcgtgatag tctgcctttt tcaaactcct gccataaatg atgattcaaa gccttatagc
     1741 tggtttcgat ttctggtgtc aatgtgattc cttgttctgc aaacaaagca cttaaagcat
     1801 tggcttcagt taattgaaaa tctaacaatg tatcatctac atcaaacaat aaagttttat
     1861 atttcatctt tttgacctcc tatttaaaat aaatacttaa ctttttcatc tctgctaatg
     1921 tcaacgatcg atactcgcct actcctagct gttcatctaa ttccaatggt cccatgctta
     1981 gccgtttcaa tgcggtcact ttctttcctt gggctaagaa catctttttg acttgatgga
     2041 attttccttc ttggatcgtc aataaaaccg tactttggtg cttgtctgct ttgagtattt
     2101 ttaaatcagc cggcttacat tgatacccat cagcgaatac gattccattt tcaaatgctg
     2161 ttacgtctgc cggtgtcacc ctttcgttca caactacttg ataagtcttt gaaacctttt
     2221 tttctggaag tagcatttca tatcccaatt gtccattcga agtgatcagc aatagtcctg
     2281 ttgtatctct atctagtctt cccactggat ataatggttg gaaacgatcg gcacttgcaa
     2341 tcagatcgat tactgtcgtc ttttctggat ctgatacagc tgtaacagct ttttcaggtt
     2401 tattgagaag ataataggac tcatttgttt ctaagtgttc acctgctact tcgatttgat
     2461 gcagtaaact atctacattt cgattttgtc gaaattcgac tgtgccatct atcatcactt
     2521 gcttcaaagc aaacagccgc ttcatttcct tgcgtgtcgt ttctaatttt tcttctatta
     2581 atttatctaa acgcatgctg tttcctttct tattactact aattaattat accttgaata
     2641 ttcttgcttg caaatacatc atcatagtta ttccttgact taattaacag ttcacgttac
     2701 ggttaaatag taaagtgaat tggatttctc atacacagcg taatgacctg gtggagaaaa
     2761 gttgaatcct gactttctaa ggggagatgc gcgcatctct ccttttgcgc ttttttaagc
     2821 gccctgcctt cgatgatgtg cacgagatta gcctttagaa ttcacttaaa taaaatctgt
     2881 ccgttaccaa agcagacagt cacattttaa ggaggaattt tggttatgtc agtatcatta
     2941 gaagtaagta aaagagaagt acgtccccgt tcattaagaa acaaacttcg tcacgaaggg
     3001 aaagttccag ctgttgttta tgggtataaa gtagaaagta cccctatctc attcgatggt
     3061 ttgacactaa gcaaattgtt gcgtgaacat ggagcgaaca cagtcatcac gatggacatc
     3121 gatggacaaa aagtcaatac attggttcac aagatccaaa cgaacacttt taccaatcat
     3181 ttcgaacatg cagaatttct atctgtaaac atgtcggaag aaacagaagt cgaaacagaa
     3241 gtcgttcttg ttggcgaatc agtgggtgct aaatctggtg gagtgttagc tcaaaacttg
     3301 tatacagtag tcgtatctgc tacaccagac aaattgcctg aacgaattga agttgacgtg
     3361 acaaacttgg aattaggtga ttctattaca gtagccgatc ttccaaaaaa cgacgattac
     3421 aaattcgtga ccgacagtga agagcaaatc gctgctgtag tcgctcaaag tgaagaagaa
     3481 gaaagcacag gtgaaggtgg cgaaccagaa gtgatcggtt caacagaaga ataatactga
     3541 aacaatcagg tggtgttaga agcggcgggt cagcagcttt taacacgcct tttttatttc
     3601 taatcgttta ttttcatatg gggcttccac ttttgtaaat ggctttacaa acgaaaaatc
     3661 ctaatttacc aagcttttcc tcgcatactt ttatcgtacc tttataaaaa tttatacttt
     3721 gaaaaaaagt attcaattat tgttgcattt ttcctgattc tttattagaa tgaaccctcg
     3781 ttgaagtaag tatttctagt ttatcctagg attaattata aaaataaaac attcgttgat
     3841 tcgaaggagg ttaaacagat gtttgaaagt tttgatagca gccgcaaccg ttacgcttca
     3901 gttggtgtcg tatcaagttt gccagatgaa ttgattgaca gtatatggtt tattattgac
     3961 ctagatctta agggagtcat tccattagaa aatatattaa cctttgattt gatcgaaaat
     4021 cgtggaaaag tgacgatgca tttttctcaa gcaggaagca atgtggaaat ggatattgat
     4081 ttgccgtttg cctattcgaa ccaatttcct gctcaagtat acgcctatga tgacggtacg
     4141 agagaaacga tccttttacc aagtgagatt agacaatatt aaggtgatag ataaacgtgg
     4201 atgtccctta ttttacagac caggccaagt tgttgattct ttgactcaat tcttggcttc
     4261 tttttatgga gtttcataaa ttatcattga tttctaattg gtattctcag gataaacgct
     4321 atatactact aactaaattt taaagatata aggagtttaa aagatgcgcg atttaacaaa
     4381 aggaagcccc gctaaactga ttttgatgtt cactgttcct ttactgatcg gaaatgtttt
     4441 tcagcagttc tacaatatga tcgatatgat catcgtgggt cagacgctag gtaaaaatgc
     4501 gctggcagcg gttggtgcaa ctggaagcct gacatttttg atcattggct ttgcccaagg
     4561 tttaacagct ggtttagcca ttattaccgc acaacgttac ggtgcaaaag attatcgggg
     4621 tctgaagaaa agttttgctg ctagtgttgt cattagtctt gtcgtcactg tgattttaac
     4681 tgtcctaagt ctcctgttta ttcgtccgat gcttcaattg atgcaaactc ctcctgaaat
     4741 acttgatcaa gcacaaacat ttatttcaat tattttatta gggatctttg catcagtcag
     4801 tttcaatttg ctttctaatg tcattcgcgc acttggtgac agccgcacac cactattctt
     4861 tctgatcatt gcggtcatca tcaacgtcgt acttgatttg atctttatta tctattttgg
     4921 catgggtgtg gaaggtgcag ctattgctac agtaatcgca caagtttctt ccagcgtact
     4981 gtgtctagtg tatatcaaga aaaaaatgcc tttgttacag ttacgcaaaa aagatttcaa
     5041 atttgaaaaa gaagagtttg ctgtacacct aaatgctgct ttgccaatgg cgtttcaatc
     5101 ttcgatcatc gctgttggtg ctatcgtgtt acaagcagca ctaaatagtc tagggacaga
     5161 tgtcgtagct gctcaagccg ctgctggtcg tatcgaccaa tttgcaaatc agccgatgat
     5221 gtcatttggt attgcaatgg caactttcac tgcacaaaac tatggtgcga aagaatatgg
     5281 ccgaatcttg caaggggtac gtcaaacttt actgatgagt gtcggattta gtctcttagc
     5341 aggtgctatc gtcattttct tcggtcattt ctttgttcaa ttgtttgtta gcccatcaga
     5401 aacacgtgta tttgaattag cacaaaccta cttcaatatc aatgggtctc tttactggat
     5461 cttagcagtc ctgttcattt tacgctacac acttcaaggg cttggacaaa gcaagatccc
     5521 tacgatcgcc ggtatgatgg aattgcttat gcgttctttt gcagctatcg ttcttacagg
     5581 aatgtgggga tacccaggag cagcagcagc ttctccttta gcttggatcg gttctgttgc
     5641 cgtgttgctt tactcttata tgcgttcgat gaaacaattg aaacacatgg gtgaagagga
     5701 acatttcaca ttagaacatg cagaagcaag atagccttga ttaaaagaaa tcgttgcggc
     5761 taaaaatgaa aacttttatt gaaaatatct tcttcgttta ccgaaaacag gttttttaga
     5821 taacaaaaag gctgtgacaa aaaatgtcac agcctttttt cttttattct gtttttcttt
     5881 ccgtggactc tactttgaaa taatcgatat gtgcatgctg gtattctaat accgtgaaac
     5941 ggaatgatgc aatctcaatg attgttcctg cttttatttc tttatatcgg ctagaagcaa
     6001 agcccgcaag tgtagtaaaa ttcgtttctt caaactctgg aatctctaca tgaaaataac
     6061 gctggaaatc atctaatgtt agtttgccgg agatgatata agagccatct gactgttccg
     6121 ctatcaatgc ttcgtccaaa tctgtctcat ctcggatttc cccgacgatt tcttctaaaa
     6181 tatcttcaat cgtcactaag ccgcttgtcc ctccgtattc atcttttaag atagcaatat
     6241 gcttaccctt ttttcgcatg atcgtcaata atttttttat agggatcgtt tcagttgtta
     6301 cgatcggctc ttcaatcaac tgttctactg tcagctggtc atctttataa gattgcttga
     6361 tcaaatctgg caaggtgaca taacctaaaa cattgtcttt tgattctaag ataaccggat
     6421 agcgagtatg tccttgttca atcgaagctt ttatcgcttc tttgacggtt tctgaagctt
     6481 cgaatacttg catggacgta cggtctactt gtatatcttt tgccaaggta tcatcaaatt
     6541 caaacacgtt ttccaaataa taatattctt ctttggtcaa ctctcctttt tcataagaat
     6601 tcaatgcgac taatgtcagc tcttcttgag acaatgtctc ttctccttca gatacgagac
     6661 gcacacctaa tagcttccct agccctgcag ctgaatgatt caatacccaa ataaaaggaa
     6721 acattacttt ataaaaataa tgaagtggtt taactacgaa caagacgacc ttctccgtat
     6781 tgacgatact atagctctta ggaagcagtt cgccaataac cacatcgata tacgtaacta
     6841 aaataaatcc cagcgccaca gagattgtac tgctaatagc cgaactaaaa ggtagtttac
     6901 cgatcactgg ttctagtaaa gccgcgacag atccttcacc gacccacccg atgatcaaac
     6961 cggttagcgt aattcctaat tgactagctg ataaatagtt atctaaatgg tgtgtaacat
     7021 gaagagctag cttggcgttc tttacatttt ccttttctag ttgttccaat cttgatcgtc
     7081 tgattttcac taaagcaaat tcacttgcta caaaaaatga agtaattgca atcatcaaaa
     7141 ataaaataat gaaattgata accatattct cccgcctttc tctttttcta ttgtaccctt
     7201 tttctacaaa aagattgaaa ataatgcgta ttcatattta ggaataaaaa aggagatgcg
     7261 gcatttttca gccacatctc cttatcactt caaaatcatt gcgttacttg ttgctaaaca
     7321 gctttttcat gacctctgat aaaaacggta ttcaaaagct tgcatctacg gcattaagcc
     7381 caaacagatg aaaaacatga gaagctgttt ttatctgctc gttcttactg cttgttgcag
     7441 tacagctttt tcatgacctc tgataaacgg tgttcaagta gctgacattc gacattagtt
     7501 caggtcaaag cgctactttc acaaccgctc tttcaaccat gttttccgag tatttccaat
     7561 gataagcgga acagtttcat gttttacttc gctgtactct agcccaaacc atgtttctgg
     7621 cgaggtagcg atttttttga ttgccagttt tgcctgcatg atttgacgtt gccattttcc
     7681 tagagttgtc acattggaaa ctacttcatc aatcaggaca aattggaaat cgccaacttc
     7741 tcgccctggt gtcagagagt atctttgtgg ctgttttggc aaacggcctt gtttcatcaa
     7801 atcatggatg acttggcgaa catatacgtt gatttcctgt tggaccctga aacctaagaa
     7861 cagattcact tggacaataa aatcagtgtc catcatatct acttgatatt ctttcgtata
     7921 tggctcatcc gtcacttcca catgaacaaa ccaatagact cgtgctcttt taggccgttt
     7981 atctaaaatc gaatagatga actgtcggcc aactttatct tcagccatat caggaaccaa
     8041 gaagaccaca tttgtctgat agattggtaa agaagtatca tcacgtaatt ctctaagctg
     8101 cgggatataa tctctcaaag acacatcctc ggttgacgat tcgcgaataa tgttcccttg
     8161 ttcccaaata aacatcacga ctaagatgat caaaccaatc agaacggcta caaaaccgcc
     8221 tcggaagaat ttgacaacac ttgagataaa gaaaacgact tctatcgcac cgaagaaaaa
     8281 ggtaactaaa tatgcaagcc aacgagaatg cccattttgg ataagataaa agtaaagcag
     8341 tgctgttgtc atcaacatcg tcacagtgat cgatagaccg taagcagctt ccatatgatg
     8401 agacgttcgg aatgtgacaa ccactagaga acaggcgatc cataaaatca gattgactgc
     8461 tgggatatac atttgcccga tactgttccc aggatacatg atctttaacc gaggcagcag
     8521 tttcaacttg attgcttctg aaactagcgt aaacgaacct gtaatcaatg cttgcgaagc
     8581 aatgactgca gcgactgttg caaaagcaac gccgatcacg atccaacttt gaggcatcat
     8641 ttggaagaat ggattcaggt tcttgatttg ctgtgcttca gggttttgat aaacattcaa
     8701 caaccacgca gcctgcccaa aataattgat aaccaaacaa attttgacgt aaggccagct
     8761 cagacgaata tttcgtttgc cgacatgtcc aagatcggaa taaagcgcct ctgcacctgt
     8821 cgtagccagg aaaatatttc caagaatgaa caagcctaat ttgttatctg cactaaaaag
     8881 cagctggata gcataataag gattcagtgc acggataact gtccagtctt gactgaagtt
     8941 cattaatccc attacgccta aaaaagtaaa ccaagcgaac atgattggtc cgaatgcttt
     9001 tccgacaata tctgtaccaa agcgttggac catgaataaa acaaaaataa taactaaagt
     9061 gataatgacg atcacgttct ggttattacc gaaccggtca aaaaactgcg gaattcctcg
     9121 caagccttca atcgcagtcg ttaccgtcac agcaggggtc aataccccat ctgctagtaa
     9181 ggcagctcct ccgatcattg caggaatgat caaatatttc ccaccttttc ggacaagtgt
     9241 gtagagtgag aaaattccac cttcaccatg gttatctgca ttcaatgcaa tcacgacata
     9301 tttgattgtt gtcagtagag tcaatgtcca aaaaatcaat gagactgatc cgataacaaa
     9361 atcaggattg attcctgaca atccgccatt atcttcaaca atcgatttca taacgtaaag
     9421 cggacttgtc ccgatgtctc cgtagacgac tcccatcgct acaagcaggc cagccattga
     9481 tatctttttg gtattgtgcg ttgttgccac gtttttccct catttcttgt tatatggata
     9541 tcctttaggt aagcttgaat gatagatgat attcttatcc atgacacccg ctttcctaaa
     9601 ttgcttctaa ttatccaagt aacacactga agtgtcaact tatttgaata aaattattct
     9661 ttctttggac gttctctgat acgtcttgcc acaaatgaat aaagagcaag gcaaaaaatt
     9721 gcacccaata atgctggtat caaataaaaa ccgccgagtt ccggtcccag tggtcctagt
     9781 aaaaattcgc cgagccaact acctaaaaaa ccgataatga tatttccaga tacgcctccc
     9841 gggacttcct ttcctaaaat tgcgccagct atcaaaccta atataccgcc gataaataac
     9901 gaccataaaa aattcagcat ctcctttccc tcctttatcc atatttctca cttttatttt
     9961 acgctttatt cagaaggact ccaaaaatat gcgccaagaa actccagaaa aaaagaagtt
    10021 gtaacaaaag tgttcagctt atttccgtag aagctgcttc tggaacaccg tgaatcagag
    10081 gttgtgaaat cagcggtttg acctgagtat tagagaaaca aacggaaaaa tagttcctca
    10141 tattttgccg ttttttgagc taatatcgag ggacagctga ttgaacatcg tttattggag
    10201 aggttgtaaa aaagctgttc tgcatcaagt aataagaaca gccaagtaaa aacagctcct
    10261 aatgttttta acttggctgg acttattacc gcagatgcaa gcttttgaac accgtttatt
    10321 cgaaaaaaaa ggactgtgac acggcttttg tcacagtccc cttttttcga ataattattg
    10381 tccccctgtc accttcacga tcacaagtac attattccta tgaattaaat tatttttctt
    10441 catttttcgt tgaaccatct tcgttcaaca ttgcttttct tgacagattt acgcgtcctt
    10501 gtttatcgat ttcagttact ttcacaagga tctcatcacc tagtttaaca acatcttcga
    10561 ctttattgac acgatcgttt gctaattggg aaatatggac aagtccatct tttcctttga
    10621 tcaagttgac gaatgcaccg aatttttcga tacggacaac tttccctaga taaacttcac
    10681 caactttgac ttctttggtc aaatcttcga tgatcttgat agcttttttg atcatttctg
    10741 catcagctga agcaatactt acttttccat cttgatcgat atcgattttc acaccagttt
    10801 catcgatgat tccgttgatc gtatcgccgc ctttaccgat aacatctttg attttagcag
    10861 gttcgatctg gatcatttcg atttttggtg catattggct taattcttca cgtggagcag
    10921 caatcgttga agtcaattct tctaagattt ccatacgtgc ttgttttgct tgagttaatg
    10981 cttcagttag gatttgttct gtgattcctt gaatcttgat atccatctgt aaagcagtga
    11041 taccatcttt tgtaccggca actttaaagt ccatatcgcc aagatgatct tccagccctt
    11101 ggatatcagt taggatcgta tagttttcac catcagaaac aagtcccatc gcaataccgg
    11161 cgactggcgc tttgattggt acacctgcat ccatcaatgc taatgtgcca gcacagatac
    11221 ttgcttggga agaagaacca tttgattcca atacttctgc tactaaacgg atcgtataag
    11281 gaaattcttc ttctgaaggg attacttgtg ctaacgcacg ttcacctaat gcgccatgtc
    11341 cgatttcccg acgccctgga gagcctgcac gtcctgtaga accaacagaa aattgaggga
    11401 aattgtagtg gtggatgaat cgtttgctga cttccacccc taaaccatca atgatttggt
    11461 gctctcctag aggtgcgagt gtacaagctg ataaagcttg tgtttgtcct cgtgtgaaca
    11521 aacctgatcc atgtacacgt ggcaataagc tgacctctga tgacaatgga cggatttcat
    11581 ccaatttacg cccgtcagga cggatcttat cgatggtgat caattcacgt acgacatctt
    11641 tttcaagatc ttctgtgatt tgtttaactt ctttcaacaa gtgatcttca tcttcatgac
    11701 ctgcaaattt ctcagcataa gcttcgcgga tatcgatctt cacctgctcg atattatctt
    11761 cgcgagcaag tttttcttca gtcattactg ctgctttcat tgtagcgtaa gaagcatcaa
    11821 agatttcttt tttcaatact tcatcaactt gcagtaaagt cacttccatt ttttctttcc
    11881 ctactgcttg aacgatttct tcttggaaag caactaactc tttgatagcg tcaaaaccaa
    11941 acagcaatgc accaagcatg tcttcttctg aaacttcttt cgcgccgctt tcaaccatat
    12001 tgatggcttg tttcgttccg gcaacagtca attcgatatc tgtttgttct gcttgttcta
    12061 ctgttggatt caagacgtac tcgccattta cacgaccaac ttctacgcct gcgattgggc
    12121 cgtcaaatgg gatatctgag attgatagtg ctaaagaaga acctagcatt gctgccatag
    12181 ctggcgagca gtctgtttct acactcatca cgatgttcgt tacttggact tcattacgga
    12241 agccttctgc aaacatcggg cgaattggac ggtcgatcaa acgggcagtc aatgttgctt
    12301 ccgtacttgg acggccttct cgtttgatga aacctccagg gattttccct gctgcataca
    12361 ttttttcttc ataattgatc gttaatggga aaaagtctgt atcttttgct tctttagagg
    12421 ccacagctgc acttaagact actgtatctc cataacggac taaaacggct ccgtttgctt
    12481 gttttgctag ctgaccgact tcgatttgta agggacggcc gccccatgtc gttttgaata
    12541 cttgtttttc tgacataact tctccttttc cttctcgtga aagcaagacg ctactaaaca
    12601 aatgaaaact gccgaaagcc gtcttttgag cagctttcat ttggttagta ggagtccatc
    12661 tagcttgatc acggaatttt acttaattga tatacgagta aaaaaagtga gattcatgtg
    12721 aatcccactc tttttgacta aaattaacga cgcaagccta aacgtttgat caattcgcgg
    12781 taacgttgaa cgtcagtttt acgtaagtaa gctaacaagt tacggcggtg accaactttt
    12841 ttcattaggc cgcggtatga atgatggtct tttttgtgca cgcgtgcatg ttcattcaag
    12901 tggttgattt cttcagttaa tacagcgatt tgtacttctg gagaaccagt atccccttca
    12961 tggcgagcgt attcgttgat gatttcattc ttgcgttctt ttgaaattgc catttctttc
    13021 acctctttcg attattcccc tgcgactgag taaaacgttg gtgattcgct taaccaagtg
    13081 gcaggtcatg tgcctagagc acacagctat actttacctg aaaccgggtt gaaaatcaag
    13141 tagttaatca ttaagaaaag gtagttttca aacaatctta ctactacttt tccatttttg
    13201 tggtaaacta taatgcgaaa atagacttga aacacagtct tttaagaaag gggtacatat
    13261 tccatgatta caatggatga tatcattcgt gaaggaaatc cgaccttacg cgaagttgca
    13321 aaagaagttt ctcttccatt aagcgaagaa gatatctctt taggaaaaga gatgcttgag
    13381 ttcttaaaaa acagccaaga tccaatcaaa gctgaagaac tacacttacg aggcggtgtt
    13441 ggcttagctg ctcctcaatt agatatttct aaaagaatca ttgctgttca cgtaccaagt
    13501 cctgacccag aggcagatgg accttctcta agtactgtta tgtataatcc taaaattttg
    13561 agccattctg ttcaagatgc ttgtttaggg gaaggtgaag gctgtttatc tgttgatcga
    13621 gaagtaccag gatatgttgt tcgccatgcc aaaatcactg tgtcttatta tgatatgaat
    13681 ggtgaaaaac acaagattcg tttgaagaat tatgaatcga tcgtcgttca acatgaaatc
    13741 gaccatatca acggtgtgat gttctatgac cacatcaacg atcaaaatcc atttgcacta
    13801 aaagaaggcg tattggtgat cgagtagaga attggcaggt tccttcgata ctatgctaca
    13861 agaaagcttt ataaaaaagg ggagtgctca aaagctgcac ttcccttttt tatgtttctc
    13921 cactaatcga aatttagata gacatctaga aatcgcaatt ccaaaaaatt ctgtgtattg
    13981 gatacgcatc ttttcttatt ttttcttatt tcttccatat gggtgtttat ctcagagatg
    14041 atagaatagt ttctaggata aaaagtagca gctacgatgt tatccttcgt agaggattcc
    14101 tgcttcagct agtttttgtt tgatgttttt cagcatatgc ttttctgggt agcggatcgt
    14161 atgcagatgg atgccgcctg ttaattcgga taacaaagta gcattacttt tttgataacg
    14221 tctcataaag gaatcgatat cttgtggcgt tttgatgtgc aaagttcctg ctaactcacc
    14281 gtaaagggga tgttccacaa ttacatcaat gatttcacca ccattttcaa cgattagtct
    14341 cagttcttct tctgtttgat cttttccatg ctggacagcg attttactga tgtgcccagt
    14401 attggtttct tctgtttcga ggatataacc tcttgctgtt gccacgatac ttttacctgc
    14461 agctcgtagt aaagcaatat cgcctacaat gatctgacgg ctgactccaa aagttttcgc
    14521 aaacttgcta gcactcactg gtttttctgt atttgccaag gtttgcatga tttgttttcg
    14581 ccgtgtctct ccttcgatca cacttattcc tccttcattt tgttttggta ttcgcgcgag
    14641 tgtttcatca aatcaacata cgtgtctgtt attgtttcct tatatccctt atttttcagc
    14701 agactaacaa ctttatccaa tacttgctgc tctctttttg catcataaac tgcttggttt
    14761 tcttcttttt tcacttgtcc tattttagtt accgtatcca ttcttttttc taataaagca
    14821 accaactctc gatcgatcat atcgatctta tgacgtaatg tttcaagaga ctcttctgtt
    14881 agttcttcct ctactgtctt gatgatacga gcaggatttc ctgcaatcac tacattgtcg
    14941 ggaaaagatt tggtcacaac cgaacctgcg ccgactacta cgttgtcccc tagagtgaca
    15001 cccggcgtga cgataactcc tccgcctaac caaacattat taccgatttt aatgggtttt
    15061 gcgtactcca gaccgctgtt acgtttcact ggatgtagtg gatgcgtcgc cgtgtaaagc
    15121 tggacattcg gagcgaacat gcagttatca ccgatttcaa tcgtgctgac atctaaaaat
    15181 gtacaattga aatttgcata aaaattctcc ccaacaaata tattatatcc gtaatcaaaa
    15241 ttgataactg gctccatata gatttttttc cctgtacggc caaaagtctc tttcaacaat
    15301 tgggatcgca gttccgctga ttctgcttgg ttgatgattt ggctttgact tcttgcaaac
    15361 atacggtcgg caaccagctc aggatcattg gcaaaataaa gctcgcctgc aatcattttt
    15421 tctttttcgg ttttgaattc agtcataatc tgctcctaat tcttgtattt ttttgaaaac
    15481 aaccgctccg tcttcttgaa taaacgtata aggctccgct aaataaacag gcgtttgatt
    15541 gattactaag attttggctg acggctggcg aaactgtacc agatcacaaa acggatgaac
    15601 ttgaaaactc gttccaacaa tgacgatcag ctctgcttgg ctgacggcat aagccgcctg
    15661 ctccatgact ccatcttgaa acccttcacc atataacacg atgtctgggc gtatttgtcc
    15721 tccgcatgct tgatgtttgt cgctgtgaag atattctttc cagtctaccg tttgttgaca
    15781 ttttcgacaa tgacattgat acagactccc atgaaaattg acgagttgcg ggcttttagc
    15841 ctttgcgtgc aaaccgtcga tgttttggga aacaacccaa acattttttt ctttcgctag
    15901 atgtgctatt tccaaatgaa tgatattggg ttttgcttca ggatgataaa tctttttgac
    15961 aaattgatag aatttatccg gttcattcac cattgcttga tgactcagca agtattccgg
    16021 ctgctccatc ccgtggtaga ttcctgacaa agatcgatag tctggcactc cagaaggtgt
    16081 ggatacccct gcaccggtca aaaatgtaat ttgctgataa gctaatatct cttttgctgc
    16141 ttcgtctact gttaattgtt tcatgttttg tcacctcact ttccattata gcccatactc
    16201 gaacaaattt attgttgaaa agtcagaaaa atgggaataa aaaagtgtta tgggcatttg
    16261 agcaatttat cacaatgttc actgacaaaa gaatgaaaac gtgttacaat actgctgtat
    16321 aaaagtgagg tgaatcgata tgttaccatt ctttatttat tggggcgtta ttctggcttg
    16381 tatcgcctgg ttagcgttaa gcgtttattt ctctgttttt tatcttgtac gcaaagaaaa
    16441 tggaaatctt tgggcttttg ctttattcaa cgtgattgcc gcaattgttt tagccattac
    16501 attagccgta tatcgaacat ggggctgggg aatcacccaa tactcaagtt tgatttatct
    16561 aatattagcc atttatggcg tcgttgttct tttgcaagcg atcctaggac gtgagccaaa
    16621 gaaagcggca gcttaaatga tcgagatgga actggacaca ggaaattttc tgttctagtt
    16681 ctttttttat tgtattacat acatttttgt gtataattat actatcgttt gcaatggata
    16741 gatgattcac attttgattg ttttttcggt aaaagtaaag atttctatat ttatcagtat
    16801 tttttcaaaa accagcagtt atagattgac aaagcctctc gagtatcgta aacttttttt
    16861 gtataaataa ctgaatacga gatgcctcaa tcaatgaggt agaggtcgcg agaatcatta
    16921 accctgtgga gtgaagcaaa catggagaag caggaatagg gaggatcgcc gaaatgtgca
    16981 cttttttgct tggagtgtat gttgggacgc aagttaagag cttgcggact gtcttagcag
    17041 tgatgctaag ttgcgctatg ttttgtgaga ggtttatcac cttatggaat tttagcggcc
    17101 tttttatatc tataaatcgg tcgcttttta ttttttcaga taaagcttta ccgcatttca
    17161 tctagaccgc tcgtgtatca tataatcaga aagggagaaa aaaatgaaaa aaaatatggt
    17221 ttcagttgcc gtactatttg cttttgtctt ctcactattc agtgtgggat ctctggcaaa
    17281 tgcagatgaa aaaacaccga gcgatgagtt tcgcgtaggt atggaggctg ggtatgcacc
    17341 cttcaactgg tctcaacaaa cagatgagaa taatgccttg ccaattcaag gccaaaatag
    17401 ttacgccggc ggttatgatg ttcaaatcgc taaaaaagta gcagatggtt tagggaaaaa
    17461 attagtcatc gtccaaacga aatgggatgg tctggctcct gcccttcaat caggcaagat
    17521 cgacgcgatc atcgccggaa tgagccctac tgctgaacga cgaaaagaaa ttgattttac
    17581 cgatccttat tacgaatcac aattagtagt agtagttcaa aaagatagca aatatgcaaa
    17641 agcaaaaagt ttagcagatc tttctggagc aaagatcact gctcagttaa atacattcca
    17701 ctatactgtg atcgatcaga taccagatgt gcagaaacaa caagcaatgg ataatttctc
    17761 agcaatgaga acagctttag cttctggaat gatcgatggt tatgtcagcg aacgtccgga
    17821 aggtgtaacg gcaactagtg tgaacaaaga cttggaaatg cttgaattca gcggtgcaga
    17881 tggcttccag acaaacccgg aagatgttca gatttctgtt ggtatgcgta aaggcgaccc
    17941 ggatatccaa aaagtaaacc agattctttc tggcatctct aacgatgaac gaaccaaaat
    18001 tatggaccaa gcagtcaaag atcagcctgc tgcaactgat agtgaagaaa aacctggcat
    18061 catttctgat ttcactacga tttggaaaca atacggcaat atgttcttac gaggtgctgg
    18121 acttaccttg ttcatcgcat tgatcgggac agttgtcggt actacacttg gattactgat
    18181 tggtgtcttc cgttcggtac ctgaatcagg aaatgcactg actcgcttct tccaaaaaat
    18241 cggaaatgca cttctttcta tctatgtcga agtattccgc ggaacaccga tgatggtaca
    18301 agcaatggtc atcttctacg gtctggcact cgcttttggc atttcattga accgaacgat
    18361 tgccgctttg tttattgtct ctctcaatac tggagcttac atgacagaga tcgttcgtgg
    18421 ggggattttt gcagtagatg aagggcagtt cgaagctgcg caagccattg gtatgaccca
    18481 tggccaaacg atgagaaaag ttgttattcc acaagtttta cggaatatct tgccagcaac
    18541 aggaaatgag tttgttatca atatcaaaga tacagcagtt ttaagtgtaa tcggcgtagc
    18601 tgatttgttc ttccaaggaa actctgcttc cggtgcgaat ttccaattct tccaaacatt
    18661 tacgatcgtc gggatcatct acttagtcat gacctttacg atcaccagaa tcctgcgggc
    18721 ggtagaaaag aaaatcgatg gtccttcagc ttataccaag cttgaagaaa tcgacaattc
    18781 aaatttgcag gaataaggag gaagaatcat gaatgaaaaa attattgaaa tcaaacatct
    18841 aagaaaaagc ttcggtgaaa atgaagtatt gaaagatatc agcgtaacag tcaataaagg
    18901 tgaagttgtg acgatcatcg gttcttccgg ttctggtaaa tctactttct tgcgctgtat
    18961 caatttactg gaaaaaccaa caggcggcga gatcatttat aatggagaaa atgtattagc
    19021 tcctaaatat aatttaccta aatatcgaac gaatctaggt atggttttcc aatccttcaa
    19081 cctgttcaac aatatgaatg tcttggaaaa ctgtatgtct ggtcaaacaa ctgtcctgaa
    19141 acgagataaa gaaactgcca aaaaagtagc aatcgaaaat ctggaaaaag ttggtatgga
    19201 tcgttatatc gaagccaaac cagcacaatt atctggtgga cagaaacagc gtgtcgcaat
    19261 tgctcgggca ttatcaatga atccagatgt attgctattc gacgaaccta cttcggcgtt
    19321 agaccctgaa atggttggcg aagtgcttaa tacgatcaaa gacttagcac atactggctt
    19381 gacaatgctt atcgtgacgc atgagatgga atttgcaaaa gatgtatctg accgtgtcat
    19441 ttttatggat aaaggtgtga ttgcagaaga aggtacacca gaagatatct ttgtccatcc
    19501 gaaagaagaa cgtacaaaag aattcctttc acgtatttta aatgcttagg atcaatagct
    19561 gattgggaca aagagctgcg gtgtttaccg cagttctttt ttatgaatta ctcataaaag
    19621 gtaaatttct gaa
//
LOCUS       DAFLWC010000057        19221 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.058, whole genome shotgun sequence.
ACCESSION   DAFLWC010000057 DAFLWC010000000
VERSION     DAFLWC010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19221
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.058"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            5..304
                     /locus_tag="L1V17_001847"
     CDS             5..304
                     /locus_tag="L1V17_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236612.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(401..835)
                     /locus_tag="L1V17_001848"
     CDS             complement(401..835)
                     /locus_tag="L1V17_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1236613.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1067..1777)
                     /locus_tag="L1V17_001849"
     CDS             complement(1067..1777)
                     /locus_tag="L1V17_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBN1236614.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(1767..2627)
                     /locus_tag="L1V17_001850"
     CDS             complement(1767..2627)
                     /locus_tag="L1V17_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HBN1236615.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(2632..3270)
                     /locus_tag="L1V17_001851"
     CDS             complement(2632..3270)
                     /locus_tag="L1V17_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HBN1236616.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3285..3584)
                     /locus_tag="L1V17_001852"
     CDS             complement(3285..3584)
                     /locus_tag="L1V17_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1236617.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(3627..5111)
                     /locus_tag="L1V17_001853"
     CDS             complement(3627..5111)
                     /locus_tag="L1V17_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBN1236618.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5131..5592)
                     /locus_tag="L1V17_001854"
     CDS             complement(5131..5592)
                     /locus_tag="L1V17_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1236619.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(5610..6677)
                     /gene="ulaG"
                     /locus_tag="L1V17_001855"
     CDS             complement(5610..6677)
                     /gene="ulaG"
                     /locus_tag="L1V17_001855"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HBN1236620.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            6895..7665
                     /locus_tag="L1V17_001856"
     CDS             6895..7665
                     /locus_tag="L1V17_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBN1236621.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(7938..8765)
                     /locus_tag="L1V17_001857"
     CDS             complement(7938..8765)
                     /locus_tag="L1V17_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1236622.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9333..10568
                     /locus_tag="L1V17_001858"
     CDS             9333..10568
                     /locus_tag="L1V17_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBN1236623.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(11567..11827)
                     /locus_tag="L1V17_001859"
     CDS             complement(11567..11827)
                     /locus_tag="L1V17_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBN1236624.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(11854..13155)
                     /locus_tag="L1V17_001860"
     CDS             complement(11854..13155)
                     /locus_tag="L1V17_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1236625.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(13447..13905)
                     /locus_tag="L1V17_001861"
     CDS             complement(13447..13905)
                     /locus_tag="L1V17_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1236626.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(13918..15249)
                     /locus_tag="L1V17_001862"
     CDS             complement(13918..15249)
                     /locus_tag="L1V17_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HBN1236627.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15260..16702)
                     /locus_tag="L1V17_001863"
     CDS             complement(15260..16702)
                     /locus_tag="L1V17_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1236628.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(16689..17453)
                     /locus_tag="L1V17_001864"
     CDS             complement(16689..17453)
                     /locus_tag="L1V17_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HBN1236629.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(17557..18432)
                     /locus_tag="L1V17_001865"
     CDS             complement(17557..18432)
                     /locus_tag="L1V17_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBN1236630.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(18687..18771)
                     /locus_tag="L1V17_001866"
     tRNA            complement(18687..18771)
                     /locus_tag="L1V17_001866"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18735..18737),aa:Leu,seq:caa)
     gene            complement(18789..18860)
                     /locus_tag="L1V17_001867"
     tRNA            complement(18789..18860)
                     /locus_tag="L1V17_001867"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18826..18828),aa:Gln,seq:ttg)
     gene            complement(18870..18942)
                     /locus_tag="L1V17_001868"
     tRNA            complement(18870..18942)
                     /locus_tag="L1V17_001868"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18907..18909),aa:His,seq:gtg)
     gene            complement(19004..19088)
                     /locus_tag="L1V17_001869"
     tRNA            complement(19004..19088)
                     /locus_tag="L1V17_001869"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19052..19054),aa:Leu,seq:caa)
     gene            complement(19109..19179)
                     /locus_tag="L1V17_001870"
     tRNA            complement(19109..19179)
                     /locus_tag="L1V17_001870"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19145..19147),aa:Cys,seq:gca)
BASE COUNT         6041 a         4023 c         2985 g         6172 t
ORIGIN      
        1 aaacatggat tatactgttg aatttgacag tgaactactt aagcaatttc cacaagaaga
       61 acatttcatg tataaagaag caatttccca caaagtgaca gagtatttgg agcataattt
      121 ttttcgtata aagccagtgc gtactcgttc ggcaaaagga atatacgaga tgaaagtcaa
      181 aattaataaa aaaaattatc gcatagcatt tgctttaaaa aaaaatcatg tgttcatttt
      241 ttatattagt tcgaatttgc aaaaaattgt atttgataaa gaggtgagta aaaaaataaa
      301 atagctgagc attggaggat agattgagtg atactaagtc tatcctcttg tttttctaaa
      361 gaactaagct agaatttttt cttttgtacg ttattatatg ttatttgtca ttaccaaaaa
      421 gcaccttttt tcttctagta tctatgacat aagaaatacc acccatttcc tttacttgaa
      481 caaatcctac tgattcataa aatttttttg ttttctcagt atcatctgtc aataattcga
      541 tttggactgg tccataacta gtgatcttct ccaaagcttc attcaaaagc actttgccta
      601 ttccttggcg ctgatacctc ggatgaatga ggatatcttg aataaatgcg atcgtcgcaa
      661 aatcagtgat ccaacgaacg attccgataa tcttcccttc cccattacgc tttatcagag
      721 attcagattg ttcaaatgct ctagctaacc ttgcagtgtc ttttgtgtaa ttcgtccaac
      781 caacgctctt atataattca gaaatctcat cgatcataag ggaatcaata ttcatttttt
      841 tcttcctttc ttatacaatt ctccctctaa taatacagtt ctttgactat ttaatctatc
      901 acatataact ctcctgtaaa gattctctcg attccttaaa attcctcttt ccttttagaa
      961 tgcatacttt ttgataaata aaaaggttgt gataaatttt cttcacaacc tctgtttctc
     1021 tctatcaagt gttatctttt aattttctac ccttacccta gcatctctat tgcccgtagt
     1081 atgcatactt tccatgtttg cgaaaataat gtttatctag taaatattgc gggatttcac
     1141 atatattggg gttgatcagc tcgttttctt tggccatcag acaaatttca tctaagatca
     1201 aactgttttc tactgctttc ataggtgaat ccccccatgt gaacggtcca tgtccataga
     1261 caagtactcc agggacttcg tttggatcta attttctttc cttaaacgtc tcgacaatca
     1321 cattccctgt atgaacttcg taagcttctc ttacttcttc tttcgttaat tggcgtgtac
     1381 aaggaacctt accataaaaa gcatcagcat gagtcgtgcc ataagctggc aaatcgcgtc
     1441 ctgcttgcgc ccacatgacg gagtgcgtgg aatgagtatg agtaatagca gttatatctt
     1501 caaaagtttg atacaaaaca acatgtgtgg ggagatctga agatggtttt aagctatctt
     1561 cttctattat atttcccgac aaatctgtta ccaccatttg atctgcttgc atgcattcat
     1621 atctgacacc gcttggctta atgacgatga ctcctagctc acggtccact tcactcacat
     1681 tgccccaagt caatttgact aatccgtatc gcggcaatgc cagatttgct tcaaggacac
     1741 gttgcttcat tgctgcaatt ttttcttcac aagacatcat agccagcctc cttcaattta
     1801 gaacttaagt agtcttttgc ctgctggatt tctcttcgaa agtcttggct tttttcactc
     1861 cacatttcaa tcagaaatgt tccatcataa tctagacgtt tcaaatgtct taataatcca
     1921 agaaaatcaa cacaaccgct accaaaagga acatcacgaa actggcctga atattctttt
     1981 gttacagggt aagtatcttt taagtggata gcagtgatat aatcgatccc tttctcaagt
     2041 tctcgagccg gattattttc cggccatgcg gacaaattgc ctaggtctgg atatacttgt
     2101 agaaaaggtg aatgaatctg ttctttgatt tctaaaaatt ttgaaatgga gttcataaat
     2161 ggatcatcca tgatttccac ggaaagaatg atgccatatt tagaagcttc ctttacgctt
     2221 tcttttattc cttcgataaa gtcttctctg gaattcattg atttctcttc ataataaaca
     2281 tcgtatccag ctatttggat tactttgacg cttagattat gcgccaaatg gattgctttt
     2341 ttcattagtt gtttcgctgc ttttttcttt tctggatcag cagaaccaaa cggaaatcgc
     2401 cgatgcgcac ttaaacaaat cgaatggata cgtacaccgg agctgaacat ctcttctctc
     2461 agctcagcta tcttttcttc agaccaatct aatcgtgcta accgctcatc cgtctcatca
     2521 atcgacatct cgataaaatc gaagtccatt tcttttacaa gggaaaaacg ttctttccat
     2581 gaaatatctt tgggtaacgc tttttcataa atcccaattt gagccatttc cttaccccca
     2641 gatacgaatg atctcatctt tgaagttttg tgcggccttc atcggatcat ttgctgctgt
     2701 aataccacga ccagtgataa aggtatacac atcgatccct tcaaataagt gtaatgtgtg
     2761 tggatttaat ccaccagtta cagaaacatt aaagcctagt tcaatcagtt ttttgatctt
     2821 cgataaatct ttttcacccc aagtttcacc agataacagc gcatcacggc tttgatggta
     2881 gattacctgc cggataccga tgttatgcca atccatggct tgttcaaaag tccaattgcc
     2941 gtagagttct acttgcaatt cacctatttc tttttgtgct gcctccatag ttggaatcgt
     3001 tgcacaacaa atgactgtca tccagtctgc tcctgctttt gcaacattac tcgccactgt
     3061 tcctccagcg tctgcacatt tcgtatcagc gactagtttt ttatctggga acatactgcg
     3121 aatacagcga atcgcttttt gtccttcctg taagcaaaga attgtgccca cttcaataat
     3181 atctactaca tcaccaactt tcataacatc tcctaatgca tgttctaagt cattgtgatc
     3241 taacgcaatt tgcaaattcg gcctgctcat cttagttcct tcctttactt gtttttttgg
     3301 taccactttg tttcagcaaa tttttcactg atttctttga ctgacatcac atttttgata
     3361 ccgataactg taactccttt tttctctgcc tgagtaaaca tattcaaaaa attgactggc
     3421 gtaaaaacta catcgtattg gccagctgaa ctttttccct ctgaaatggc acaatgatgg
     3481 attttggtaa ttggtacgtt tagttctttc attgcttttt ccacacttct catcatcatc
     3541 aagcttgttc ctgatccatt tgcacacgat actaaaattc tcatcttaat ccctccatta
     3601 tgagtgttgt ctaatcagat tttcttttat actctctgct tttctgcata tgtgtcatag
     3661 tcttctacaa tcaaaaaata accatcagga tttttccgat attgtaactg cggaatagcc
     3721 aataaaccaa tgacaactac ggcaattcca gcataaccta ggactttcat gattactgta
     3781 aacaatggcc aagctgttgc ccagtcgaac atcccgatat aaccaccgta tgttgacatc
     3841 ccaatccatg tagcgaataa tgctgaaccg cctacttgta tgattcctga aagaaacggg
     3901 aacaggcaag cggctttgaa tccacctcgg ttattggcat aaactgctat aacggcatta
     3961 tcaaagaaca acggaatgaa accggctatg acgatcgttg gtgatttcaa taaaatcagt
     4021 aaaccaatca tcaaaaactg tcccaaagca ccaaacaaga acccaatcgt taccgcattt
     4081 ggcgaaccaa agccaaaagt agcagctacg tcaattcctg gaacagctcc tggtaaaatc
     4141 gtgtttgaga ttccttggaa agattgagtt agttcatcga cgaatgtccg aacacctaat
     4201 tgcaagatcg ccagatatac cgcaaaattt aaagaagtcg tcataatgta gaataagaaa
     4261 ctctgccctt cttgcatgaa ttgcgcttga atcaaataat ctttgcctag tacaatcaga
     4321 atgatcccaa agaaaaatag catgagtaac gaagtagcaa ccatattctc attgaaaatc
     4381 gacaagaatc ctggtaattt gatatcttca atttttttgt cttgcttgat tgatctattt
     4441 ttcttttcat cccgcttttt catccactca gctaattttg caaatataaa gattccgaac
     4501 atttgctgat gtgccactgc aaatccggca ccttctgtca attcctgcgt gattcctact
     4561 gttaagttag aagctactgt ccaataacaa cctaaaatca gtcccataaa aatcaatgct
     4621 tgtatcctac ctagatcagg aaagcaaaac agtaaaatcc aaaaagcggt agctgcttgt
     4681 tgaacctgaa cgtttccggt agtgaaaacg gaacgcagtt tcgtatattt ctgaaaacgg
     4741 actaataaga tatttaaaac aaatgcaatc agtaataaaa tcatcacatc tccaaaggta
     4801 cggccaaatg tctccattaa tccagcatcc acagcatttt gtccaaaata aggatctgta
     4861 accatggcat ccaaattgaa ccgttccttt agtccaacca agattggccg aaaattattg
     4921 accaaaccac cagagccaac agtcaaaata aagtaaccga ccgttgcctt taagaatcca
     4981 gcgatgcatt catgaagcgg gcgtttcagc aaaatatagc ctaataacac gataaaacca
     5041 atcaggtatg ctggctgcgt caagatattt gttgcaaaat acgtccaaat gcttaacaaa
     5101 aattccccca tcttttttct cctctatcaa ttaattatat tctgccatca caacttggta
     5161 atcatcgatg gagttcgtag agatgagacg ctcaaccaat ccatctgtca ttaataattc
     5221 ggataatttt tggatatttt ctagatgttc ttctggatct tttgctgcga gtgtaaaaaa
     5281 caaactagcc gttttctcct cattctcccc ttcactttca aaacggattg gctgtttcaa
     5341 cttggtaaat gaaatagctg ttccaaaaac accatcactt ttttctgaag aatgcggcat
     5401 tgctacttga ggtgcgatca caatataagg accgtatttt tctacacaat ggatgatctc
     5461 ctccacatac gtttcatcaa taatttcctt atcgatcaat acaagacagc tttcggcgat
     5521 agcttcacgc caatccgtga tttctttatc tgggtaatga atcaattgat ggtcaaaaaa
     5581 gtatttcagc aagaaactcc ccttctttct tataaaaacg acggaaacgg tgtatcattt
     5641 tcaatcgaga agacatcttc aaatcctcga taaaaattaa actcaagatc atctttgttt
     5701 gtcggataga tgaatttccc gcctacttgc cagatataag gtttaaatcc atacttcagg
     5761 cgatcctttt tgaatttcca aatttcagtg atctcttttg gatcagccat aaaattagac
     5821 caaatatcgt agtggacagg aatcactact tttgcattca atgactccgc catgcgcagc
     5881 atatcaacag aagtaacttt gtctgttatc cctcgtgggt tttcaccata ggcccctaaa
     5941 cagacatcga ttttgtgttc attaccatgt ttggcaaata aattggagta atgtgaatct
     6001 cctgcatgat aaagattccc tcctgatgtt tcgaataaat agtttactgc aatttgatcc
     6061 atctcctgag gcatttttcc ttttaatacc tcttctggat cttcacaagt gaccaacgct
     6121 gtccgatcaa acgcttctaa agctactaca ttgatgtctt tgattttgac tgcatcacct
     6181 ggctttactg taatcgtttt ttcttcagga attccccatt tttgccacgt gcgaaccact
     6241 tcttttggcc caatgaatgt tgcttcagga caattttgat gaactgctgc ggctgtatgg
     6301 atatctagat gatcggaatg gatatgtgta acgattaaag cgtctacatt ttttatcgca
     6361 aaaggatcga ttacgaaagg ctgagtacgt aaattaggct gcatattttg aacgccactc
     6421 atacgcatca tctgatggcc ttttttcatc atgccattcc catgactacg ttttcccgtc
     6481 ccacaccata gatcacataa aatattcgtt ccttcatgac ttttcagcca aattcccgta
     6541 cagcccagcc accacatagc aaaagttcca ggatccacta cttctgtttc gatttcttca
     6601 ttcaagtatg tgccccactc aggaaatgtt tctactaacc acttttcttt tgttacttca
     6661 ttgacagttt tactcatttg cttgctcccc ccatatcgtt gttccaactt acaagtaaat
     6721 attaatgtgt atcagcatcc atgaaaaccc ttttatatga ccgtttgttt tttatatgat
     6781 tttctttcag taatcaatga ttgtttcagt ataataaaga cagatatgaa tgtttaaatg
     6841 aacaactagt caaataaatc catggatcaa gatgtccctc aggaggcaaa agtcatgaaa
     6901 aactcacttg tcaatattga aaaacgtcaa aaagaaattt tggaactgct tcagcagact
     6961 gaacaactat caactttcga attagctgaa tcccttgatg tatctattag tacgatacga
     7021 agagatttaa atttattaga agaaaaaaac gagatcatac gcaattacgg ttattgttct
     7081 tataattaca aaaaccagac tgattttgat caatctggtc ctgaaaggat taaacaagcg
     7141 attgccagag aagctagtaa atacattaac gattatgata cgctgtttat caattctagc
     7201 tcgactgcgt tgaaaacact ggattttctt caatctaacc atttgacagt cattacaaac
     7261 aacgtgaaaa tcaattactc tccgcacaaa gataattgta gttatatttt aactggtgga
     7321 gagatgcgct ttccaaaaga agcactagtg ggcgacatcg cattaaatac gatttcttca
     7381 gtcaatgcag acatttgtat cattggctgt agcggagtcg atgtagtaca tggggtcaca
     7441 acaaagatat taaatgaatc aacgatcaac gaaatgatgg tcaacaagac aatcaaatgt
     7501 aagattttag tcgctgatca tcgaaaaatc ggactgacat caaagttcaa gattgctgat
     7561 atttcagtct ttgattattt gatcactgat aaattttgtt ctgaaaaagt attagaggag
     7621 atcagaaata cggggataaa aaccattcaa gtagattcat tttaagaacc aggacgtaaa
     7681 tatgtaaata ggattatcaa aaaaatgaat aacaaattta tcgataaatg aaaaacacgc
     7741 tacgctcaaa ttgataaagg aatcccaaga tgtatccatc caatcgatac catcataatc
     7801 tattgcttct tttataaccg ttatatgttg cctaaatagg aatcaaacaa tatcgaaaaa
     7861 aggaggtatg acaaaagtca cacctccttt tttcgaataa acggtattca aatcagaaca
     7921 ctgatttcac aaccacttta tttcaggtcg ttttcaatca cctttaccgc gtaatcattt
     7981 ccgttgaaac gcgctatttt ttttgcgtcc atatatcttt ctaaataatc atcttctcct
     8041 aattgcttat ggcaagaagc aatttcataa agcaagtatt ccaatgcata agtcgattta
     8101 tgtttcttat tatactcaat acccttctca cataattgga ttgctttatc ataatcctcg
     8161 attttacggt aataggtggc gatatcataa tatacaatgc agaccatcag attatcaaaa
     8221 tcagtctcac tcaatatttt aagtgtacgc tccacataaa ctttcgcaaa atctaattct
     8281 ccttttgaca agtagatcat tgccacgttt gcagctgctt gtaagtgatg gatatctgtt
     8341 tcggtcgttt gttccaacac ttgattaaaa taaaataatg ctgcatctgg ttttttcgca
     8401 taaagatgat caagcagtcc ttgataaaat aaaatttgat ttaaaagatc agaattactt
     8461 actttttcct gatcgatcgt ttgtaaaatt ttataagatt cttggtattt tgatacagaa
     8521 ttcaatgatt gaatctcatt tatttttttc ctgattttgt cttcttctgt ttctactaat
     8581 atatcggaga tctcgacatt cagctttttg caaagcgcac ttaagatatt gatgcctggc
     8641 gacatattct tgttttcgat attgctgaca gttgcttgtt cacaaatgcc ttctgctaat
     8701 tgtacttgtg ttaacccctt tttctttcgg tattctttta gtaatgctcc atctacttta
     8761 atcaaaacaa tttccttccc tttaaaaaat tatttctcct ttatatcata cacaaaaaaa
     8821 agttctaaac aaccaaaaat gtttagaaca gaataaaaat tttaatttta aaataatatt
     8881 caaattaaac aactggcgta tctgctcctt gatttctttt tgtgttatct gaataattat
     8941 cgtttacagt tataacacat agtgaaaatt gtcatggcga gaaagtctaa gaatattttt
     9001 aaacataact atttctttct tacgtgtgta taatgacgac agcacaccta tcaattaata
     9061 taattatttt atttttttat gttctcatgt ttatttttaa tgacacaact tctcgtattt
     9121 atctggcaca acatataaat cgatcaaaaa attgttgcgt gtttttttga aaattggagt
     9181 ttcaacttga ttacaaaatt taaatttaga agttgtgaaa acagcgagag acagtttaat
     9241 attcaaaata tacataggct actcgaacgc tgtgtttttt agtatactag taagaaacga
     9301 agggatagac tcattccaat aaggaggatt tcatgaagac aattcttttt gctcctgcag
     9361 tattcaattt agctgagaca acacgaatga ttgaggttgc caaagctatg aaagaccgtt
     9421 attactgtgt attctttggc ttttctaaaa cttttgctcc tttgatcaca gaaagtggct
     9481 ttgagtatca tttactagcg ccgatcctta cgaaaaaaca agaagaacaa atcataaaat
     9541 ttgaccagtt gcgtacactt aaaaaccctt ttaccaaaga aatggttgcc tctcgtatca
     9601 ctagtgaaca gagtctgatt gctaagtttg agcctcgact gattgtgaca ggttcgaatg
     9661 tgacaatttt tttatcggcc cgcaataaaa agattccttt agtatatgtt aaaccctatg
     9721 ctttgagtga accttttttt caatcagagc atgcgctgat gccccacgag ttacgtttct
     9781 tcggcccttt aagcaatccc ctttggcact ggacaaaaaa gcgtatagta aatacccgat
     9841 ggatccccaa tgccttcaaa cacgctgcac aaaaagaaat gcttccttta ccaaaaacaa
     9901 gtttacaaat gatggatgct gatctaaatc tcatcacaac gcctaaacta tttttggaag
     9961 aagaacagct gccggaaaat tatcgaatcg ttggtccaat ttttgctaag ctcagtactt
    10021 ccttgcctga agaagtgcta acttttatac agcgaaagca acaagaaaga aaacgtatta
    10081 tctatttcgc aatgggtagt tcaggcaatc cgcgtatgtt acgcaaaatt ttgttcttct
    10141 tacaaaaaca accggatcta gcggttattg cacctattga ctatctgctt gatgacattc
    10201 aatctgactc agaagatctt ttaataacag aatatctgtc tagtcatctt ttgcatgaat
    10261 tcattgattt ttcttttatc cacggcgggg aagggaccgt ccaaactgcc tgtgaatccg
    10321 gcaaaccgtt tatcggtgtg gggatgcaat ttgagcaaag ctgtaatatt gactattgtg
    10381 taaaatacgg aaacgcaatc gccctcacaa aaccagtgac tgaaagaaaa ctgcagattg
    10441 ctctgcgcga agtttcttca cccaagattc gtcagcaggc acgcacgctg caagccgttt
    10501 ttccaataaa tggtccacaa caagcaattc aagaaatcga aaccttcctg agcaaccacc
    10561 caatatagtt tcaagtagaa aaagcttttt taatagagac tcatcagtaa tttcgctatt
    10621 cgagacccag acagtgaaaa tacaaaaaaa gtaaatagtg gattgaaaag ttagagttac
    10681 ttaaattacg gtgtctaaaa aacacaaaat catccttaaa ataaaagatc tgacgctatc
    10741 caaatgagca taggtagcgt ctgccattta ttcttagtca aattctttga cacctttctc
    10801 tggttggatc atctcaacgt ttcttcaaaa gaaagaccat aataattagg caaatacatt
    10861 ttcttaaaat gtgtcatata gatctagaag catcgctttg tagagatttg tgccgctagt
    10921 cccctcaaca attactaaat caaatgtagg atttaccact ttatctttga taatcaacct
    10981 ccctcttctg ttgagacaat gatctcgcaa tccgatgcat actcctatat aaactgccag
    11041 caatccccac atattgagta gatcatgtca gaatgttcta tgtcgtcagc aacgatacac
    11101 taaaagtcac gttcaccatg actgattgct attcccagca caattatttc tatacacgtt
    11161 tcatgatttg aataaacact cacatcatac atattaccat tcatacacca tactgcagcc
    11221 cctactatat ggttgtaagc tcccaaatct atatttgact tgatcacttt ggtagtagat
    11281 ctactaattc taaatccatt gctgataaaa tttccatttt ttcctccttc tttctgccaa
    11341 aacagttaaa acaataataa tctttatgta aaaaagggct gtgacaaaag ccttgtcaca
    11401 gtcccatatt ccgaataaac ggtggtcaaa agcttgcatc tgcggtaata agttcaacca
    11461 aacgaaaaat aagccaacat ttcacaaaaa tttaagaagc aattttcgta aatttcttct
    11521 tatttcttga agctaaccac ttctgttaca accactttta gaacatttaa agcttcgatg
    11581 tgacaaacca tctatgctgc tcgatcataa aattgatagc aaaaattcca caaagtacat
    11641 atgtccccca tgaaaacaaa acattcatat gcggtacaat gatctttgga agaatcacga
    11701 tcaaaaatga tgccagtgcc caaatccatc gattgatttg aatatgatat gtagctagca
    11761 tattcaatat aaggtgacta gccgttaata aaaagataaa aacaaaaaat aaaatcagcc
    11821 aatacattgt ttcccacctt ctaaaaacca aacttagaca gtctggactt cgttttctcc
    11881 acgactttgt tcatctgaca gcatcttttt atcataagct tttacaaatg gataatagat
    11941 aataaatgct atcaatgtgt tgatcatgat caagataaca acacgccagt catttcctgc
    12001 tgaaagataa ccgccgattg gagctggtaa tgtccatgtt ggcaaaacag taaatctatt
    12061 gaccatttct aatttgactg caaaataact gataatagtc aaaactaaag gaactaagtt
    12121 gaacgggatg aacatgtaag gattcaacat cataggagct ccaaaaatta tgggctcatt
    12181 gatattgaag ataccaggaa taatagaaaa acgaccaacc tctttcaaga attttgattt
    12241 acagaagaat ataaacaaaa cagataccac gatcgttgct cctgcaccac caattgttac
    12301 cgtccattga taaaactgtt caggagcgat atagggtaat tgggtggcag ctgtaccatc
    12361 tgccaatgcc tttgcattct catccaacat gatcagccac attggacgaa caacagcccc
    12421 tacaatactc atgccatgga taccaaatga ccacaacaaa tggatcaaaa acattggtag
    12481 taaaacacca agcaaattat tccctaaaat attggttaaa ggctcgaata acgataataa
    12541 ggcagcgttt acatcaaagc ccgcgacgct tcgaatcagc caagtaattg ttaaaatgac
    12601 tgcacctgga atcaatgcct caaaactacg ggcaacagca ggtggcactt gttctggcat
    12661 tttgatagta atatttcgat ttttaaagaa acgatatact tccactgcaa aaatcataga
    12721 taagatcccc gcaaacatcc cagatgctcc caaagaactc ataggtaaga cccagccaag
    12781 aggtgcctct tcaggagtta aaacgtttac aggaacttgt aacataaaga acgttcctaa
    12841 agataatata ccacctgtca cactatctaa tccatatgat ttagctagat ccgaacccat
    12901 aacaaaagtt gcataaatag ccatcaatcc catcgtcatc ctaaagggta aaacaatcgt
    12961 tgccgaataa ggggcaataa attcattcca tccaggaaac ggtaaattga taaagaccat
    13021 aaaaaatgtc ccaatcaaaa tcaatgacaa tgttgaaaca accccattac gaattgctaa
    13081 taaatgacgc tgtgtaccaa tttttgccat tggtgggaca agtttctctt cgacccattt
    13141 catcagcttt tccactaaaa ccactccttt tcaataaaat atgaaccatt cattgcatga
    13201 caacgcaaag aatgttcata actaattata taattaagaa attttatttc aatatattct
    13261 cttaaataat caaatttatt tttaagaatc ctgaaaataa gttttctaaa tcataggagc
    13321 aacaaaaaaa ttcgataatt aacaaaaatc aaaatgatta aatctagtga ttgaaacata
    13381 tcatttcaaa aaaattttgt aaattcaccc ataaatatca ccctatttaa cttttttcat
    13441 cgtacactaa aattcaaaac aactatcttt aatctttact tcttggtttt gttttaataa
    13501 atttccttca aaaatgcctg gagaaactac aatgatcacc gtatcttttt gtgcttgctc
    13561 caacttcttc aaatctataa tagctaacag tgtcccttct tttacctcct ggttactttc
    13621 aacccgtatc tgaaacggac ttccttcgag ttcaactgta tctaaaccca tatggatcag
    13681 tatttttctg ccagattcac tttcgatcgt tatggcatgt cgggtaggaa atatattatc
    13741 gattattcct ttaactggcg catggatata tccatcatga ttcgttatag cgtatccaac
    13801 tcctatcatt tttgaagaaa agacctcgtc ttttactgct gttaatggaa taatttgacc
    13861 actagctaca gcttttagaa tgtttcttgt tttaaagaaa tgcacttttt atcacctcta
    13921 ctttaatgct ggccaatatt ttttgtttac tttgatcatt tcatctagta ttttttttgc
    13981 gactctggca tttggtacgg tttgattcaa tgtaaatgct tgtaaagctt tttgataaga
    14041 accttcaaag taagcatcta ctagtaactt ctctactgca acttgtgcct ccatcaatcc
    14101 tttatgaaaa tcactgattg gttttcttag tgtaattggc tccacaccag ttgcaccaac
    14161 atatgccggt atttcaacaa ctgcatctga ccgtagattc ggaatcgccc cttgattagg
    14221 aacgattagc ataaagcgac gacgatcatc attcaacaag gaaatagcta tatcgacgat
    14281 atattgtcca tgctccccaa aattaaagtt caatacttct tccacaatac cgcggcgtat
    14341 tttatcagcc atttctttgg tatttttctc tcgtccatcc atgaccatat tagcacgtgt
    14401 atactctttg tcagtatgct caacgaccat atcaggatat aagtaatact ctaagtaatt
    14461 attcgggata ttacttggaa aatttttcgt gatgactgac atcatttgaa aggttttttg
    14521 ccaagtttta tctcctatat taaaatcggc gacttgcatt tcttttgtta ttagtttttc
    14581 aataatctct ggcataattt ctcgttgcaa ttctttatca taaatcgatg tataccagcc
    14641 aaagtggttt aaaccataat acgtaacgat ccaattctta cgatcataac cgtaattcac
    14701 tgcaatcgtt tcttcaattg aaatagtcat atcacaggca ttaatcattt ttacattcgg
    14761 atatttacga cgaacagctt cagaaacgat cgactctgga tttgtataat tcaaaatcca
    14821 tgctttgggg gcatagtctt gtatatgatc gacaatttcc aataaacctt tgattgagcg
    14881 catcccataa gcaaatcctc cgagtccaca cgtttcttgt cctactaatc catgtttaag
    14941 tggaatcttt tcgtcctttt ctcgcatctc caatcctcca acacgaattt gtgagaaaac
    15001 aaaatcgcat cctgtaaaag caagctttgg atcatccgtt gcacgaatgc gaatatttga
    15061 aaaacctttt cttttcagca taaatttaac aatcaagtac atatccatat ttctttcttc
    15121 atcaatatca tataaacgta tttcagataa tggcaaccgt ttttcattgt tcaaaatggc
    15181 ttgaacgatt cctggtgtat acgtactccc gcctccagct atagtgataa tctgtttttt
    15241 catcatcatc ttttcctttc tattcttcta ataatttatt gaattctgcc ataacataag
    15301 tcacttctaa gccgatgata atttgataat ttttttcagt tggtttaatg atcccgctta
    15361 tccctaattg cttgattcgc tgttcctcga ccatggtggg atccactacc tctacccgta
    15421 ggcgtgtatt acaactatag acatccagga tattggcttt tcctccaaac gcttgtagca
    15481 tttttgttgc catatattca taatttttac ttgctaaccc taactctgtt tcttctaagg
    15541 ttacttcatt gccaaactct gccttagctt cacgtcctaa tgtctgaatg tttctcttat
    15601 tgatcaaata ataaaaagta acgtaataca aggcaaaaaa gaaaattccg attggaagaa
    15661 tcaaaatagc attggtagcg attcgaaaat tgatgagata atcaacaata catgctccga
    15721 atgtaaaacc aattcgtata ttgaataagt aacagacaat ccctgctaaa ccggcaaaaa
    15781 gtgcatggat cacgtacaac ataggagaaa gaaacatgaa actaaattca acaggctcag
    15841 tgatatttgc aataaatgaa gttcctgcac cgcttcccat gattcctttg accatctctt
    15901 tattttcttt ataagctgct ttatagatag ctagacatat agctggtata ccaaacatca
    15961 ttactacaaa aaaaactgat aaaaacagtc cagcctgagg atctccgttg ataaagcgtg
    16021 tcatctctcc tctgaaaact tccttgctag gagatgtata gcttcctaaa tcgtaataaa
    16081 tatacgtatt caacacatgg tgcagtccaa aggggatcag caaacgattc aaaaacataa
    16141 atatccccac acctaatgct cccatatcaa cgagcagttt tgcaaaatta tcaatcccaa
    16201 tttggatgag cggccagata aagcccaaaa aaacagctgc gattgtttgt agaatcatca
    16261 ccatagtcaa tgggaatttt tcgcccgcaa aataagaaaa aactactggt aatttttgtt
    16321 ctttaaagcg attatacgtc catgccgcta ctaaaccgga aataattcca ccaaaaatcc
    16381 ccatattcac ttctgggtcc ataatttcta agcctttttt caaggtagca atcgctaaaa
    16441 aaccagtaag tgcaggtatt cctttgtcct tatttttgac aaaaccgatt gcaactccta
    16501 tagcaaataa gatatccaag tttccaaaaa cggcatttcc agctgcacca attactggga
    16561 tgttcagcat atcgtcagct gataaacgca tgatcaatcc cgctaatggc atcgctgcaa
    16621 ctggaagtag catcgctctt ccaagcttct gcacatttga tttaacattc atttttattc
    16681 ctcctctatt aaatatcctc atatgttact aactcaatca aaggatcatt tttcactttt
    16741 tgagcaaatg ctgaatgaat taaaaattcg acttggtggg tacgaggata cacaaaactt
    16801 gaaccattta acaattcctg atccaaatac gctgcgtgac acatgacttc gatcgtttta
    16861 tcttctctca atatcatgag taaacttgcc aaatattctt ccacactcgt attgatttgt
    16921 cgtttttttt catcagtttc tcctacgaca tcgaaacaag gctcaaaata atcgacatga
    16981 cgaacttcat cttttcgttc aaagttgctc cgaaccggca aatcatattt ttttgctaat
    17041 gtaacaacta cctcctgatt ttcatccaaa gtatgagtat gatgatgact gtctaaatga
    17101 gttggtatga tccccgcatg ataaattttt tgaatctgag cattccattc ctgatacagt
    17161 tgatctttgt caatgttaaa tggatgctga taataagata aggatctgaa ctctccgctt
    17221 tcgataagag tatcgacagt tttgaggagt ggtttgccac acgtcaatgt taaatggact
    17281 cctacaccta gcctaggcat ttcctttctt agtttcacag catgctcgaa acccggcata
    17341 tttgccatca atgtagttga tgtcaaaatt cctcgctgat aagcatccat aatcccataa
    17401 ttcacaccat ggctatagcc aaaatcatcc gaattaaaaa tcacttttcc catttcattc
    17461 tccttctttt ttctactaaa ataggcgcaa ccaaataatc atagtccatt tactatgtgt
    17521 catttggttg cgcctataga tagttacgcc cttattttaa tagattcttg ctagatgaat
    17581 tgccaaatag atgatttcat tttcttgaat ggcaagttga aattgctgtt cgatgatatc
    17641 tttaatcttt agtgctgtac aatacgcttt gctatgttta aatgtttcag taaaaaaacc
    17701 aatattttct actggcgttt cttcctgata aatcaagcgt ttaaccagga atttgatatg
    17761 aaccattaag cgatgataag tcagtgattc tttatcataa acgtttgaat aggatttttc
    17821 tagatgggac aaaatcgtgg tcgtcatttc tactattttt aagctcttta aactattagg
    17881 ctctcctagc tcagcattaa tgatatgcat agtgatgaat cctacttcat ttgaccctaa
    17941 ctcggtttga tatcgatgat tgattcgctc gaccacttct actgctatat catattcatt
    18001 tggataaagg aatctcattt ctggcaacat aattgctgtg acatctctat cttctctttt
    18061 tcgttgaata gcaaaataaa tatgatctgt caatgtaata tagatatttg aatctaatgg
    18121 agaggagatc ctagctgtta tcagttcaat cacttcttcc gcaaaatcca taaattcgat
    18181 tggaatctgc gagactatct cactgaatcg tttgatcttt tctttagaat ctaatacaaa
    18241 taatttgtca gcatcctcaa catcaaatgg cttactcact ttagcagaaa agccaatccc
    18301 tttccccatc gcaatttttt ctattccatc gtcatcgatc aatacagcat tatgattcag
    18361 ctttttcatc acatacaccg ttaattcacc tcctctatat gataaaacaa aacaacttgc
    18421 agactccttc atacatattt ttgtctccaa acaattttta aagacaaaaa acgacctaag
    18481 aaagaaccct ttcttaggtc gtgcctaatt gaatagtagc accctacata atttacaaaa
    18541 atagtttaac acataataaa agcgttatca atatcttttt tactcgtttt atgataatac
    18601 ttgtatcgaa ttgatttgga ggtaattaca taaaaacaaa aaaaatatag caactctcta
    18661 taagaaagtt gctatattga taattatacc ggcggccggg gtcgaaccgg cacgtcctca
    18721 acggacactg gattttgagt ccagcgcgtc tgccaattcc gccacgccgg caaatttaaa
    18781 aataataact ggggtagctg gattcgaacc aacgcatgag ggagtcaaag tcccttgcct
    18841 taccgcttgg ctatacccca agaataaagg gcgaatgatg ggaatcgaac ccacgaatgc
    18901 cggagccaca atccggtgcg ttaaccactt cgccacattc gccatcataa aagatgttat
    18961 ttaatttctc aataaaaaac taagatgaag acatcttagt caataccggc ggccggggtc
    19021 gaaccggcac gccctcaacg ggcactggat tttgagtcca gcgcgtctgc caattccgcc
    19081 acgccggcaa gttgatttat tagtactaag gcggtaaccg gatttgaacc ggtgatgaag
    19141 gttttgcaga cctctgcctt accacttggc tataccgcca ttatactatt atcaatctat
    19201 aaaataaaga ataaattata g
//
LOCUS       DAFLWC010000058        19161 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.059, whole genome shotgun sequence.
ACCESSION   DAFLWC010000058 DAFLWC010000000
VERSION     DAFLWC010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19161
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.059"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            79..1506
                     /locus_tag="L1V17_001871"
     CDS             79..1506
                     /locus_tag="L1V17_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1236631.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(1598..1963)
                     /locus_tag="L1V17_001872"
     CDS             complement(1598..1963)
                     /locus_tag="L1V17_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBN1236632.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(1960..2325)
                     /locus_tag="L1V17_001873"
     CDS             complement(1960..2325)
                     /locus_tag="L1V17_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBN1236633.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2517..2765)
                     /locus_tag="L1V17_001874"
     CDS             complement(2517..2765)
                     /locus_tag="L1V17_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236634.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2764..2892
                     /locus_tag="L1V17_001875"
     CDS             2764..2892
                     /locus_tag="L1V17_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HBN1236635.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            2949..4643
                     /locus_tag="L1V17_001876"
     CDS             2949..4643
                     /locus_tag="L1V17_001876"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HBN1236636.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4647..4766
                     /locus_tag="L1V17_001877"
                     /pseudo
     CDS             4647..4766
                     /locus_tag="L1V17_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            4743..4916
                     /locus_tag="L1V17_001878"
     CDS             4743..4916
                     /locus_tag="L1V17_001878"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236637.1"
                     /translation="MQAFEHRLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQA
                     FEHRLPRGYEKGV"
     gene            5294..6427
                     /locus_tag="L1V17_001879"
     CDS             5294..6427
                     /locus_tag="L1V17_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HBN1236638.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            6458..6778
                     /locus_tag="L1V17_001880"
     CDS             6458..6778
                     /locus_tag="L1V17_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HBN1236639.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(6807..7271)
                     /locus_tag="L1V17_001881"
     CDS             complement(6807..7271)
                     /locus_tag="L1V17_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1236640.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(7403..8656)
                     /locus_tag="L1V17_001882"
     CDS             complement(7403..8656)
                     /locus_tag="L1V17_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1236641.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(8685..9002)
                     /locus_tag="L1V17_001883"
     CDS             complement(8685..9002)
                     /locus_tag="L1V17_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBN1236642.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(9028..9348)
                     /locus_tag="L1V17_001884"
     CDS             complement(9028..9348)
                     /locus_tag="L1V17_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1236643.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(9812..11227)
                     /locus_tag="L1V17_001885"
     CDS             complement(9812..11227)
                     /locus_tag="L1V17_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBN1236644.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(11244..12560)
                     /locus_tag="L1V17_001886"
     CDS             complement(11244..12560)
                     /locus_tag="L1V17_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1236645.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(12710..13408)
                     /locus_tag="L1V17_001887"
     CDS             complement(12710..13408)
                     /locus_tag="L1V17_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBN1236646.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(13697..14653)
                     /locus_tag="L1V17_001888"
     CDS             complement(13697..14653)
                     /locus_tag="L1V17_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBN1236647.1"
                     /translation="MEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQREILRGAFDMG
                     ITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMWEGPYGEWGSRK
                     SIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGKALYIGISNYNG
                     EDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGAITFSPLAQGLL
                     TNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQSLAQMALAWNLR
                     QKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(14766..15599)
                     /gene="msrA"
                     /locus_tag="L1V17_001889"
     CDS             complement(14766..15599)
                     /gene="msrA"
                     /locus_tag="L1V17_001889"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBN1236648.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQVERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(15774..17408)
                     /locus_tag="L1V17_001890"
     CDS             complement(15774..17408)
                     /locus_tag="L1V17_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236649.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            complement(17395..19083)
                     /locus_tag="L1V17_001891"
     CDS             complement(17395..19083)
                     /locus_tag="L1V17_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236650.1"
                     /translation="MKISKKAFLLVVLILLSTLYSVNFMRNAQEIYTTGDLSFHLSRI
                     KGLSSIFEGPINYTTFNNYGDGLNYFYPFLTIIPAVVFYGISNNLILSYVLYIWLLNI
                     CTILISFYYGEKFFKKIDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYY
                     AYGLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFV
                     VVNLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDI
                     TTYTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLL
                     QFPWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVI
                     QSKHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKA
                     ADNNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIE
                     ITTKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
BASE COUNT         6083 a         3749 c         3188 g         6141 t
ORIGIN      
        1 taactgatga tttcaaaaag aaaacatgtc ataatatttc ccatattgtg caaaaaaata
       61 caaggcggag gctctactat gattgaagaa tatattgaga aaaatatttt aagacagctg
      121 tttttatgtg ggcaattcta tgtaaataaa gaagtcaatc tagaaaagct ctccaatctc
      181 ctgcatgttt gcaaaaccac tttactcaat gatatcaata acataaaaaa agaatttgaa
      241 gaacagatcg cttatacaca tcgggaaaag gaccgttaca ctttatattt ttcagaacat
      301 atacctcgat gcaagatcat gcagcaattg tctcaaaatt cgttgttttt aaaaacttgt
      361 ctgctttatt tggaagaaga tgaacctgat tatcttcaat taactgaatg tgaattcatc
      421 tctgtcagca aagcttattc attaaaaaaa caagtattag cttattttaa tgactgcggg
      481 atcgaaatcg accgctactc ccctcgattc actgaaatgg aaagacgtct gctgcttctt
      541 aatgtgtcgt atcgtttagg cggttttaat tcttgggagc tacctgaatc gttttttgaa
      601 cgtgccgatc gtttcattga atccgtaacg gaaaatagtg gcagatttta tgataaagaa
      661 aataaagaaa tcttatcgat tggttttgct atcagtttcc tacgccagca agtgtgtgct
      721 gtgacaatag attcaaaatt tatcgaagaa atcaaaaaac gtcctattta caattatgtc
      781 gaatcagcat gggaaaacac tgatttccaa acctattata aaaaagaaga attcgccttt
      841 attttgacac tattcaatct ttgtaattat ggtttccatt cttatcagtt gattgcggaa
      901 gactttcaac agctacacca agtgtttatt gacaatactc ccgaaataaa agaactagtt
      961 gctacctttg aatctcactt caatcaagaa ttattcggaa accaaccgtt cgaacgtgcg
     1021 ctgattcatc tgatgcgttc ggcttgggat aactatcaat tattcatgcc agaaaaattt
     1081 tatcttttaa atgaggaaca gacaaattta tataaagaag tccagacaat tttttccagc
     1141 tggtccagcc agttacctta tgatctacgg ttgaatccta attgcatgcg ggcttttgtg
     1201 atcgaattga gcggaattct ccgtctgaca aaagaacatc tgactatcta tatcgtcaca
     1261 aattcggatg ttcattatct gatttatcgg gaagccttgg aagctgtaac tactttcgat
     1321 tttcaagttg caccaacaat ttattcaagt atatctgata taaagaagta tgcgcagcag
     1381 tcctcaaacc gggtattatg tgaacgtaca ttatatacac cagatgcggt ccaatatgaa
     1441 aatattattc ctatttcgat caatacgatc gatcgagcta tcatttcagc tgtgcaaaac
     1501 aaataagggg ctgtgacaaa aatcatgtca cagcctctta tttgttgaag atgcccattt
     1561 ctgtaacaat ctcttgatac acgtcaggct cacaacctca cttattttgg acatctacgg
     1621 gtccgatctc tttatttaaa aaataagaaa tgatggttcg gataactacc aacgccgcta
     1681 gttggaaaat atcctgcaag gtaggtttga taatcgattc gatgatccca gctgaaacaa
     1741 gaatttccaa acttagaagt atatagcctc ccaacatctt tttaatagca ttgttctcgc
     1801 tgactcggtc gctttgcact tttgtatgga caaataaata tttcaaaaaa tccttgattg
     1861 atagacaaac accccaaacc aataaacaga tagcaaagat atcaagtccc agtacaagtt
     1921 tttcgaaata tggaagaaga aactgcatca actctgtcgt catcctacct ctcctcttct
     1981 ttgtttttct ttgtcttcta tttcctgatt caagaaataa gaaatgactg ttcgaatgat
     2041 aataataagt gcaagcttca aaatatctgt ccaagtcggc ttgataactg actcgatgat
     2101 atcagcaacg actagtactt ccaagcttaa caaaatataa cttgctagca gttttcttgt
     2161 atctgcatta cgagtattac gttctgcata gtttttcttg acatgagacc aatcaaaaag
     2221 tttgaataga acaagaacga tcccgacaat taagataccg atagaacaaa tatttaaaat
     2281 agcaatgatc cattctagaa attcaattaa atttgagcga aacatatacg ctacctactt
     2341 tcttttaatt tgttcctatt cttttattgt aaaagaaagt taccttgttc gtctatttaa
     2401 aagttgttct aatgataacg gttcgcttaa atttttcttt ttcactctcc catttttctc
     2461 cctccatcca taaatcgtgg aagtatccaa aacaacgtag caagttaaaa taaggcttag
     2521 tccgtcatca gcttttcaaa gaagcactgt ctcggtgctt tttttgtacc caaatttcta
     2581 aaaatagaac catacacctc ctcaaatctt ttcttcttac ctaccctatt tttatttaca
     2641 ggaaaatcag acacttcttc ttttttgtca aaatttcctt tttcttctcg tcctatcatt
     2701 tggcattcta ataaaaacga actatccttg gatatagaaa gagaaaacaa ggaggcgttt
     2761 ttcatgagta aaaaattaat caaagtcggc atcggtttag gtttgcttgc ccttggcgct
     2821 gcatatctag gaaaaaagac aggactattc gaagatgaca gtcatttata tgatgaattc
     2881 gaatcaatct agcatcctat ttagttgaat cactacggac atacttggaa gacattggag
     2941 gaatcacaat gagaaaaagt aaagcaataa tgattggtgc cggtattgcc aatatggcag
     3001 cggctgttta tttgattcaa gaaggcaaat ggaaagggga tcagatcacc ttttattcat
     3061 tggatgatca cggttcaaat gatggtgcac cgaccgacac tgtagtggat gaatattgga
     3121 ataaaaacca tccattagaa aaccaaaaag gctatattgc tcgaggcggt cgcatgctta
     3181 attaccgtac ctatgtagat ttgatggatc tgttaagtcg aataccttct gttactgagc
     3241 cagggatgac tgctgaagaa gatacgagag attttgatgc aaaacaccga acctttgaca
     3301 aagcacgttt gatggaaggt ggcaaaggaa tcattgatgg cggaaaactg ggattcaata
     3361 ataaagaccg tattcttctg actaaactga ttgctatgcc tgattcagaa gaagaaaaac
     3421 tagacaatat cactatcgaa gaatatttca aagatgatcc acactttttt gaaacaaact
     3481 tctggtttat gtgggaaaca acatttgctt tcagaacacg tagttctgct caagaattgc
     3541 gtcgctatat gcatcaaatg atttatgaat tcactcaaat cgaacatcta gtgggcgtca
     3601 atcgaacacg ttacaatcaa tacgaaagta ttatgcttcc tttgatcgag tacttgaaag
     3661 aacaaggatg caaaatcatt ttgaaccgcc gtgtcactga ctgggaattc aaagaaacac
     3721 cgatgcaaga tgaaatcact gtgactggtt tgaaaattac caatacactg actcaagaag
     3781 aagaatacgt tgtggtcgat gaagatacag cagttatttt cactaatggg tccattacag
     3841 attcagctac tttaggagat tacgaaacac cagctgtaga aaatatggat tatggtgcag
     3901 cttctagtct ctggaaaaaa gccagtgaac gtttctacaa cttgggaaat cctgacaaat
     3961 tctttgctga tcgagatgca agcgaatggg tcagctttac cctgacgacg aaaaaccatt
     4021 tgttgttgaa tgaaatcacc cgtatcacga ctcaagaacc aggaaatgcc ttgaattcat
     4081 ttatttcaac cacaccgatc acgccgttag gccaaaaaga tgtcaatatg tctattgtcg
     4141 tgcatcatca accgcatttt acgtctcaga aaccaaatga aacagttatt tggggttatt
     4201 tcctttatcc aagacgacgt ggcgaatttg tggataaaca gtatattaaa atgaatggaa
     4261 aagaaatgct agaagaactg attggacaac tttcaaaagt agatcctgga ccagtgaata
     4321 ttcgtgaaaa agaaacagaa attttcgaca gcgtaataaa taatatccct gtctatatgc
     4381 cttatgcttc cgcgttgttc aataatcgtg ccaaaagcga tcgaccaaaa gtcattccta
     4441 aacattcgac caatctggcc tttacaggag aatttgtcga gcagccttat cagatgatct
     4501 ttactgaaca aagtgctgta cgttctggag aaatcgctgc tttccatttt gcgggtattc
     4561 ctatgtcccg tcttgtcaaa acaccgcgtt acgacaaaga tattcctact ctagctcgtg
     4621 ccgcaaaaaa aatgtttgaa taatcaagag gttgtgaaaa agctgccctg catcaagtaa
     4681 taagaacaac caggctaaaa cagcttctta tgtttttgat ttggttggac ttattaccgc
     4741 agatgcaagc ttttgaacac cgtttaccaa gaggttatga aaaagctgcc ctgcatcaag
     4801 taataagagc agccaagcta aaacagcttc ttatgttttt gacttggtta gacttattac
     4861 cgcagatgca agcttttgaa caccgtttac caagaggtta tgaaaaaggc gtttagtttc
     4921 gagtatgaag aaaaattttg tgaaaatggt tcctcacgtt tttgcataaa tttgacttaa
     4981 taccgagaaa ctgatccctt ctgtcataac ctctttttat ttatgtctgt ttctttttga
     5041 aaacaactat tttttcaacg tttactctct tgccaatcca acatcatcta acggatacaa
     5101 ctatttcaat gattaccatt acactaaaaa atcggaaaca cacctctccg aacacaaata
     5161 cataagacta tagaatgttt catttaagaa aaaaagcgtt tcattatcaa aaaggtaaga
     5221 tctcctttaa aatgaaatta tctgtagtac taataatgca gacaatttta tgaatctgaa
     5281 aggagcatct ccaatgaaag cagtcacttg gcaaggaaaa cagaaaatgg aaatcagaaa
     5341 cgtagatgat ccaaaaatat tagaaccaac agatgcaatc atccgtatca cagcaacagc
     5401 catttgcggc tccgatctgc atctttacca tcatggtgaa gcagttttgg aaaaagggta
     5461 tgttgtagga cacgaaccaa tgggaatcgt tgaagaagtg ggatctcaag ttcaaacatt
     5521 gaaaaaaggg caacgtgtgg ttatcccttt taatattagt tgtggtcatt gtcatttctg
     5581 cctgaatcac atggaaagcc aatgtgatga atcaaatcca gatcagttat atggcgggct
     5641 tttcggattt ggcaagttga acggtaatca ttggggtggt caagcggaat atctaagagt
     5701 tccttatgca gactctactt catttgttgt accagataat gatcttcctg atgaaaaagt
     5761 tttatttcta tcagatattt tgcccacagc ttattggagc gttgaaaacg caggagtaaa
     5821 aaaaggcgat acagttgtga ttctaggttc tggtccagtc ggtctattcg ctcaaaaatt
     5881 cgctgttatg gctggagcag agcgcgtaat cgcagtagat ccagtacagc accgtctaga
     5941 taaagcggct aattacaatg gggttgaaac ttatttctta gaagacacgg cacaagctgg
     6001 aacagaattg tatgaactgg ctaaaggtgg cgcagatgtc attatcgatt gtgtaggaat
     6061 ggacggatta gagcctgtca aagaaaaagc gaaaaattta gtaagcttac aaagcggcac
     6121 aatctctcca ttacagatgg catcgcaagc tgtcaaaaaa tttggaacag tccaagtaac
     6181 tggtgtttat atgactccag cttcttctta cccgctgcaa gaatttttta tgcgggatat
     6241 cgctgtcaag catggacagg caccaattat ccatctaatg ccaaaaattt acgcaatgat
     6301 tgcagaagga ctattcgatc ctacacaaat cattactcat tcgctgccac tatcagaagc
     6361 agcacaagca tatgagatct ttgacaaaaa agaagataaa aatataaaag ttgttttgaa
     6421 accttgaatt cagtaaaaaa tacaggtgat tttctttatg cccaaaatca aacgaaatac
     6481 ccatgagatc gaaataggaa aagaagaaga tatcgaaata cgaggacgtc gcttccgctt
     6541 ctatttccaa aatcgttaca cattgatctc actggctgtc gatttattaa ccgggatttt
     6601 ctatattttt ggaagccttg cttccttaac taaaatcccc gatcgatatg gcacctattt
     6661 ttatttggct ggtgctattt tcttgacgat tcgtcctatt ctcagaatcg taaggaacat
     6721 ttttatttac gacgaaaaaa aagcaatgaa gagaacaagc aaaaaaaaag aggcatgaga
     6781 atttttcaaa tctcatgcct cttttttcac cctatcgtat cactttgata cagacgagcg
     6841 gtcgtcccac tttcttcctt gaccattgtc aaaaatgtcc actcgtatcg ttcataaaac
     6901 gtggtatgat ctgtaattaa gtaaagtttt tcgtacccaa gttgatgcat ttcttttctg
     6961 atttccgcta atatccgctt ggctatcccc tgcttacgct tttccggttc aacaaacagg
     7021 gcacaaagat ttggtgtcag atcagggcgg ttatggaagt cgttttcaat gacgcccgct
     7081 cctccgacga tggtttcttt ttcatctaag accacatacc attgaggaat actttcctta
     7141 ttagcgattc cagtacgaat actttcctca tacacaacag caggaactcc ccattttgat
     7201 gaaaaccaat tcgcgctttg ttttactaat tctgggtgtt ctcttaattt gatccagtta
     7261 tatgtaacca atgtttaaac ctccgactaa aataaaacgt ttacaaaaat tatacaagtc
     7321 tttatgaaaa ttagcaatga caacaatagt gatgtaaaaa aaaaaacgga aaacaatcac
     7381 ttgttctccg ttttttgatt aatcaagcat ctaaagcttc ttttcttctt tcttggatcg
     7441 tagctacctt gacgaacggt agatagatca aaatagaaag aaccaaattg acagcggcta
     7501 gtacaccacc tgcaatactt tttgttgcca atacaccgcc aataattggt ggagttaccc
     7561 atggaggcat aacggtagct gctggcacta aacctgtaga agtcgcaaag taagcaacac
     7621 taactaagac cattggtgtc aaaataaatg gaatgaacat gatcgggttc aacacgatag
     7681 gtaacccaaa catcgttggt tcattaatat tgaagacacc tggcgcaatc gacaagtttg
     7741 ttacaaccat atatggtttg tttttacgtc ctactaaata aatagctaac agtaaaccta
     7801 aagttgcacc tgttcctcct aagttgacaa agctgtcaaa gaaaggtttg ttcacgataa
     7861 acggtgcgct atgtccagct gcgattgcat taacgtttgc ttcaatggct ggcgcattga
     7921 ttgtttgcat caaaggatcg accatattcg ctccgtgtaa accaaagaac cataagaatg
     7981 gtgtgataaa tgcaagcagt aaggcagatg gataagagtt tgcaagtccc ataaatggtt
     8041 cttggaccac tgtatagaaa gaacctacga tatcatcaac accgaatgca gcaaaaattg
     8101 cagcaactaa agcaaacgca gagatagtga tcattgctgg tagtaatgaa gcaaatgctt
     8161 ttgcaactgc cggtggcaca ccatcaggca ttttgatgat caatttttca tttccgctta
     8221 aacgtacaaa gatttctgtt gaaataatcc caacaataat agcaataaac aaaccgtttg
     8281 agctcatacc taatgctccg cctaaagcga agaaagagcc taaagaaatc acacctgcgg
     8341 aaacaccgtc ttttcggtag ccgttagcta aatgataagc aagcaagaaa gcaatcaaga
     8401 cagaaagaat ggcaaatgta ccgttccaag cagcagcccc gaatcctttc catgattcac
     8461 caccaaaaat tgagttcatc aattcttgga acccgggaat cggtaagtta ttgatcatta
     8521 ctgctaatgc tcctaagatc attaacggca tactcaccat aaatgagtcc cgaatcgcaa
     8581 ctaaatgccg ttgtgcacca atttttgatg ctacaggtat aaaatgtttc tccataaatg
     8641 caacaaattt atccataaat cttccctctt ttctttactg tagattacgc gttcaatcga
     8701 cgatacagat caatgatctc ttttgctaaa tctgtaaaag ctatagatgt catcagatga
     8761 tcttgactgt ggaccgtcaa aagcgtgact tcaacgtgat ttccttgtgc ttcttgtgtc
     8821 agcatctctg tttgagagtg atgtgcttgg actaaagatt cctctgcatc tttgattttt
     8881 tcatctgcta aagtgaaatc accttttttc gcagcagcaa tcgcttccat tgcatcgctt
     8941 tttgcatttc cgccaaacat gatcagaccc atgatggctt ctagattttt ttgatcttcc
     9001 atttattgta tcctccgata atttttatta tttgtttatt agtttttctg cttggtcgag
     9061 tactttttca ccattcatca tgccatagtc agccatattg attacatcta aaggaatgcc
     9121 tttaggtgct agcttttcag caaattgatt ttgcataaag cgtacttgcg gtcctaaaag
     9181 taaaacgtct acatttttag attctagttg attatccgca tctgaagcag atacagcaaa
     9241 gatgtctgct tccattcctt ttgcttctgc tgccttttgc atttttgtga ctaggagact
     9301 tgtactcatt ccagctgaac atacaagcat gattgttttc ttttccattt taaacacgtt
     9361 cctttctata cttacacttg tatataagca agtagcgtgc caactttaaa agcgctttaa
     9421 aaagttgata tcatcacatt taaggtctat accaagttgc atacacacta aaaaagaaag
     9481 cgcacactaa acacacaaat taatttttat tacctttttt cttttaacgt gcacaaaaaa
     9541 agttgtgaca caaaacttgt cacaactttt ttcaaataaa cggtattcaa aagcttgcat
     9601 ctgcggtaat aagtccaacc aagttaaaaa cataagatgt tgtttttact ttgctattct
     9661 tattacttga tgcaggacag ctttttcaca acctctcaat aaacggtgtt caatcagctg
     9721 accctgggta ttagctcaaa acgctggatt cacaacctct tttatttcaa ataaccagta
     9781 aatacaatga acatctacaa aaaacttcta tttatttata gatttcgtca ggcaaatcca
     9841 attctctctt atcaatcaaa gtctgatacc acgaagcaga ttttttcaat gttctgcttc
     9901 gttcatcgtt caattcgatt cgaactaatc catatcgatt cttaaatgca ttcattggtg
     9961 acacacagtc agtgaatgcc cataacatat agccttcgca atttgcgcct tcttctgttg
    10021 ctttgatcaa gtaatgcaaa tgctgtccga taaattcgat acggtaatca tcttgcacga
    10081 ttcctttctc atccatatac tgttcttcat attctcttcc cataccgttt tctgttatca
    10141 gccaagggat attatgataa ttttctttta gatacatggc tatatcatac atgattttcg
    10201 gatagatttc ccatcccctg gaattattca ttttcttccc aggtaaatca aagacttcat
    10261 aatatcgttc aggatggaaa ggtgtctctt cattccattg ataacgaggg gcgcgaacgc
    10321 gtttaggata atattgattg attccaagga aatctactgt atgatgctga atcgtttcta
    10381 aatcctctgt tgcaggatcg aaataaatcg attgtttttg acacaactcc aggaactctt
    10441 ctgtgtagta tccttttacc atcggatcaa aaaatactcg attataaaac aaatcataca
    10501 tataagcagc tttttggtct tctggagaat tggatcgagc atagaccatt tcaggattta
    10561 aaatacagcc aatccttcca ccataatttc cgctgcggta aatctctact gctttagccg
    10621 ttgctaaaac tttatgataa ttccacatca tccacttttt tgtgttttgt tcatgcggcc
    10681 agcgaacagc atccaaatag caacgcgttt ggggaacgat tggttcgttg aatgtaaacc
    10741 agttttttac cctatcaccg taacgatcaa aggcaatttg agcatactta gcataaaaat
    10801 caactacttt tcttgaagac cagccatcat atttttccaa aagaaaagct gggacttcat
    10861 aatgttccaa acaaatcatc ggttctacgt ctgcttcgat caaagagtcg atcatttcac
    10921 ttatatgctg agcatattct tcatctacta tacagttctc ataatcagta aaaaaacgag
    10981 cccaattgat agaagtccga taatgtgtca gatggatgga tttcatcaga tccacatcct
    11041 gctggtattg ttccataaaa ttagttgcta cggctgggcc atacccatta tgccaaacaa
    11101 aatgttcatt tttataccag ctatctataa acgaatcctg tccttctttt tttcctttcc
    11161 aaccttccgt ttgccaagca gaagatgcag caccaagaat aaaatttttt ggaatagtaa
    11221 ttttcatgat ttcctcctgt tttttagatc ccatcatttt ccacacgatt tgctactttt
    11281 acaaatggca gatagatcaa aatagaaaca ataatacaaa caagttgcgt aataactgca
    11341 ccgatatttc ctgctgttgc cagataagca ttgacgatcg gcggcattgg ccaagggacc
    11401 attacaactg ctttcgccgc aaatcctaaa gcggttgcaa aataaccaat cgttccagtg
    11461 ataagaggcg ttaagataaa cggaatagct aaaattggat tcagcatgat cggcatacca
    11521 aaaataactg gttcattgat gttgaagatc ccaggagcaa gggataactt ggtgatttgt
    11581 ttcatatctt cccgttttcc aactaacaat actgcaatca gtaaaccgat cgtgactcca
    11641 gacccgccca tactcatata catatcccaa aatggcatag taataatgtt cggtacttct
    11701 tttccagctt caaaagcttc cgtatttaca gcaattgccg ctaaaagcaa cggttcccgt
    11761 atcggcttca ccatttgatt tccatggata ccaatcaccc aaaagacttg cgcaataaac
    11821 atcaatagca aaatacccgg taacccttgt acgacacctt ctaatgggcg ttgtacgaca
    11881 ttgtaaatga tatcataaag gtacattcct gtaagttctt tgatgataaa tcccgcagcc
    11941 gcgatacccg atacagtcag aatcgtcggg aataaagcag aaaaactagc agaaacattc
    12001 gttggcacgg tatcaggcat tctcagctgt agtttcttct gtttcctcaa ccagcaataa
    12061 agttcaatag aaaggatgga gaccaacatt cccaaaaata accctttcgt atctgtatat
    12121 tgtttagcca atacgttttc tactataaca gtctgatttt cattcactaa ttcataaaca
    12181 gttggattaa cagataaata agacatcact gcgatgatac cagggaatac accatccact
    12241 ttattcagct tggctaattc gatccctatc agaaaaacag catagatggt caagaaactt
    12301 agtgtgacat agctgatggc agatgcgata ggctttaatt cttctaaaaa acgcaagaaa
    12361 cttatctgtg ctaagccatt ttccgagtca aagaccattg ctgaaaacaa tgtgccaaaa
    12421 gcacccgtaa taattaccgg aatcaatgca gcaaatgcgt tttttatcac catgatatac
    12481 cttaaattat tgattctcgt tgccacgttc cctaaaacat tggctaattt atccataaaa
    12541 ctcattccag atcccctcat tcctgcttct tctccttgac gtcatctctt tttgtctatt
    12601 agtcagcgct tacatttcga tgaacagaaa ctatttactc ctctttttta ccaaatataa
    12661 aacaaaaatt catctgatgt atttatcata aaatacatca gatgaactgt caattagttt
    12721 ctttttctcc tattattttc tgtaattctc tccgatttat tgccatatgg acagtcattg
    12781 catcaaacgc agcaagtgca ttccgccttt cgatggcctg aacgatctct gtatgaatat
    12841 cgatcgtctc gattttcaga tgctggatat cataattttt attaaacaaa gcaattgatt
    12901 cattaatgat tgggataata tgcagcaagg ctacgtttcc gctagcttct gcaatcatcg
    12961 tatgaaaatc gatgtctaat tgaacatgtt cttgtgtgcc ttctcgaaaa gaagtttcaa
    13021 tcttttgcgt taattttttc atttggacga tttgattctt cgttgcatat tccgctgcca
    13081 aacctgccat cttaggctcc aataaatatc tcagttcaaa taagtctcgt atcatccgat
    13141 cctgatcttc aatcaaagaa aaaccgagtg ggtcattggc aatccctcgc ttatcactga
    13201 caaatgtccc cgctccttgc cgaacttcaa ggatattcct ggaagctaga gcccgcacag
    13261 cttctcgcac cgtgcttcgc cccacctcta aataatcgga caattcatat tcattcggca
    13321 gtttatctcc tacttgcaac tgcatttcct ttaaatatct aaggatcttg tcagtagtta
    13381 cttctactag ggttttattt tcttccaaac cacatacctc cttttcatct gatgtatttt
    13441 ttcgtaatta ttataacacg tttgaatcat ctgatgattt tttgtataca aaattgatta
    13501 atccgttcat agacatacaa acgaagaaga tatttaccat aaaaaagact aggataaaat
    13561 tcactcctag ccttcgatca tttttatttt gaacgacaaa aaatatgatg ttcaataaca
    13621 gacgatcttc attcgattct tgatgtcatc ttttgttttt tttaatatat ggataaaaag
    13681 tttgattaca tcgtttctat tctagaattt ggtcgattct caattcttct tctggtgaga
    13741 aatctaaatt atccatcatt cgaacacttt cttgtaactg acttaaccga cttgctccga
    13801 ccagtacact tgtaacagat ttttgtcgca aattccatgc aagggccatt tgcgctaatg
    13861 attgtcctcg tgatacggcg attgtttgca gtgctttgat tttttccaga gttgatccaa
    13921 cttgttcttc tgaaaggaat ggtatttcct tacgatgtgc tctagaatct tcaggaatac
    13981 catgtagata acgatttgtc agcaaccctt gagcaagcgg actgaacgtg attgccccta
    14041 gcccttcttc ttctaatact ggagatagat cgtcttctag tagtgcacga gaaaacatat
    14101 tgtagcgcat ctgatgaata atgaacggtg cttcctttct ttttaaaatt tcagtcattt
    14161 tttttgtatc ttctccatta tagttggata taccaatata taatgctttt ccttgtctta
    14221 caagttgcat caaagcttct gctgtttctt ccaaaggtgt atcagggtct gggcgatgat
    14281 gatagaagat gtcaacataa tctagcccca ttctttggag actttggtca caacttgaaa
    14341 tgatggattt acgagagccc cattccccat atggcccttc ccacatatga taacctgctt
    14401 tgctagaaat aatcagttca tcacggtagg cttgaaaatc ttctctaaaa atacgcccaa
    14461 agtttttctc tgcagctcca gcagggcctc cataattatt cgcaaggtcg aaatgggtaa
    14521 ttcccatgtc gaatgcgcct cttaaaatct ctctttgatt atggatagga tcataatcac
    14581 caaaattttg ccataatccg agagataaaa tcggtaattt caaacctgaa tgaccggatt
    14641 tacgatattc cattttttca taacgtgcac tatctgcaat atacaatttt tctcctcctc
    14701 atcaaatctt tttaaaacgc tttctttttt ctatttttag tttactacat tttaaagaaa
    14761 aggagttaat caaaatgatt ttttcgtata tttttttgcc atttgttttt tactcgttga
    14821 tagatcagaa attgattacg tgcttgctgg atttttttat aacgtttcgg ttgttttttg
    14881 taaaattgct gatgatagtt ttctgctggc caaaacgtac cggctggttc gatttttgtg
    14941 acgattggtt ggtggaaagt tcctgaactg tctagtttct gttttgattg ttccgctaat
    15001 tctttttgtc gttcgacttg ataaaaaatc actggacgat attgcttccc tctatcttga
    15061 aattgtccaa atgtatctgt gggatcagta atttgccaat agattgtcag caactcgcta
    15121 taacttattt ctcttgtgtc ataaatgatc tccacagctt ccacatgacc tgtgtaacca
    15181 ccacttactt gatcataatt tggtttttca acatgtccgc ccgtgtatcc tgacaaaaca
    15241 gataggatcc cttttttcga ttcaaacggc tcgaccatac accagaaaca tccccctgca
    15301 aatactgcac gttcttgata gtcagcatct tgcatggcat gcttggaaaa gtcatatttt
    15361 tgctccttat caaatccttc cgtaatcaat aaataaaagt ccattacatc aggcgtcaga
    15421 ttcattcgga tagctaatgg acgtagtgtt gcttctagtt ttgataactg ttctttaacg
    15481 gatatatttt ctcttatgtc attctttgtc tgaatcaata cttttcgttc ccaatctcgt
    15541 gtattcggat tcaaaatcag attataaagt gtttgaatga atatttgttc ctcatccata
    15601 gattctcctc ctttccgaag aagacaagct agtgacttta gctgtaattt atcataaagt
    15661 gaggaaataa gcgattactt catcccccta cagatttttc gtataaaaaa gagagaatcc
    15721 ttatcgacag attctccttt ttaatcaatt tattttataa atgaaaagtt aatttacctt
    15781 ttatggaaaa ctattttaaa aaataaacat aaatatgcag ttaatgtaac aagataagaa
    15841 ataatagtcg ttactgtata acttgtgctt actttaatat cagcaactcc tttgactccg
    15901 cttatttgta ccaatccatt agcattcacc tgctccttta caggttgatg atttatttct
    15961 acattcgttc ctaaataagc atatacagga agtgtgatta cttggctctt ctcattagtt
    16021 actctatata tgatagaact accagttgtt ttataaggaa ggtttaccca ttgactgcca
    16081 atctttgctt cgtgttttat tatatgctcc ttattctcca atgaagcgat aggagaataa
    16141 tcatataaaa aataatccat tcctttagtg gtatacgcct ctactgtttc tttgtttaca
    16201 acaatatgtc ccggctgaga aattattttt tgattgaaat tttttttact agaaacagtt
    16261 aaagtgatta ataacaaaac agtcataaat aaataaaata gttctcttgt cttattgtat
    16321 cttctatttt tgaaaaatat catcgttaat atcagagaag agaatattat ttgcaagctt
    16381 aagatccgcc aaggaaattg taacaatttg gctggcgtat tttgcagaag ataccatggc
    16441 accaaactag ttgtagctag ccaagtcaaa cacgtaccat aataaatctt tttttctatg
    16501 tttgttaatt ttttaaataa aatcagggga atacataaag ataacagacc aactagtccc
    16561 attgagtaag tagttaagtc gttgttcata gcttcagtca gactatcgaa cacattagat
    16621 gcatgagcat ataaatttgt cacgctaggt ttgttgattt tttggtagag catttgttca
    16681 aacatcggat accaaaaagc actcgtcaga accaatgtca ttcctgccgc actaaataat
    16741 tttttaaata tagcaataaa atctgcattc ttgaaacctt tagaaaccaa acgaataaaa
    16801 ataaaaatga taattaatgc tgtactcatt aatgttgata gtacatggct gtacactagc
    16861 aaactcatac tcaatgctag ctttacagac ggatactttt cttcttttcc agagatgatt
    16921 tgataagcat aaaataatac agggataaca agtgttattg cgatagcttc ggcaattgcg
    16981 gaacgatagt agatgtctac tgtccgataa gcagagaaaa tatagagaca actaaataaa
    17041 aatgccgctt ttttttgttt taaaaaccgc tcgccataat gataagctac gagtgttgta
    17101 cacaagttca ataaccaaac gtaaataata tagcttacaa tcaaattttt tgtcatccaa
    17161 tataacatta cagctggaaa aaaagtcaga aagggataaa aataatttac accatatcca
    17221 gtataattga atgtctcata attaatcgga ctggtaaaaa tagtcgataa ccccttgatt
    17281 cgagataagt gaaaagaaag atctccagtg gtataaatac tctgtgtatt tttgaaaaag
    17341 atgaaagaat atatactact aactataatt aatccactca atattactac ttttttattt
    17401 attttcattc ttcttgttta tctccttttt agtcacatat cgagaatctt tcaacttatt
    17461 aggtgcaaat cgtttaaaac ttgaatacac cactaaacaa taagtcagaa tactgatcca
    17521 taaagccatg agagcagttg gagtatattt tgttgtaatt tctatcttat tttctccagc
    17581 atttacatcc acattcacta agccatgttt tttataagag tcatttacga ctttaccgtt
    17641 tacttttacc tgtgtaccta aataagcata tactggtact gtcacttttt gctttttgtt
    17701 gcttgccact gtgtaagtaa tgttattatc tgcagcttta tacttccctt tttcccacga
    17761 ttctcctact tttacttcat gtttttctaa gtgaggcctt tcttttatcg cttctgttgg
    17821 ggcgtaatcg tataatcctc ccatatctga tgttgtataa cgtgggagtg tttcttcatt
    17881 gataacaata tgaccgtgtt ttgattggat aacttttgcg taattttctt ttgctgctat
    17941 agacgtgacg agtagaaaca ccacagtagc gccaatgatt aaccatgaat attttttatt
    18001 catagtcttt ttcataaaaa caagcgttat gatcattgaa gaaaaaaaga tttggatacc
    18061 taagatacgc caaggaaact ggagtaagct tatcggtgtt ttttgaaaca aaaaccatgg
    18121 aaataaatta gttacgcata cccatgtaga aactacgcca acatagatga ttttttcttt
    18181 tttctccatt tctttcagta tgaataaagg aaaaatcaac gcaaccaatc ctaataaccc
    18241 catagtgtat gttgtaatat cgttatttaa cgcttgaatg atactatctg aaatagaaag
    18301 tgcttctagc tgcaaatctg ttttgaaggg actgtgtatt tcttgataat tcatctgctg
    18361 caacatagga taccaaaaat agctagttaa tgcacaagtc aaaaaaacag cctttactaa
    18421 attcacgacc acaaatttta tatcgttttt tatttgcttg cttaaaaaca aacgaactat
    18481 aatcatacaa gcaatcaatg cactacacaa tagtgtagtt aagacatgag tatacacaag
    18541 tagacttata ctgacagata aagcgatgac ttttttttct ctattgaata tcaatccata
    18601 agcataatat aaaacagctg ggataatcgt aagagcgatt gcttctgcaa ttgcggatcg
    18661 ataatagata tcaactgttc gataagttgc aaaagtatat aaacaactaa ataaaaaagc
    18721 agcatctatc tttttaaaaa acttttctcc ataataaaaa ctaatcagaa tcgtacaaat
    18781 atttaataac caaatatata gaacataact taatattaag ttatttgaaa ttccataaaa
    18841 aacgactgca ggaattattg taagaaaagg ataaaaatag ttcagtccat ctccataatt
    18901 gttaaatgtt gtatagttga ttggcccttc aaaaatagaa gataaccctt tgattcgtga
    18961 aagatgaaaa gataaatcac ctgttgtata aatttcttga gcatttctca taaaatttac
    19021 tgaatataaa gtactaagta agataagaac tactaaaaga aatgcttttt tacttatttt
    19081 catagatttg ttgttctcct tttttaattc tattttcagt atactagaat tgtctttttt
    19141 taataagttt tgcgttaaat t
//
LOCUS       DAFLWC010000059        18531 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.060, whole genome shotgun sequence.
ACCESSION   DAFLWC010000059 DAFLWC010000000
VERSION     DAFLWC010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18531
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.060"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            126..773
                     /locus_tag="L1V17_001892"
     CDS             126..773
                     /locus_tag="L1V17_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBN1236651.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKLLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    902..1118
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1166..3811
                     /locus_tag="L1V17_001893"
     CDS             1166..3811
                     /locus_tag="L1V17_001893"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBN1236652.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            4121..5434
                     /locus_tag="L1V17_001894"
     CDS             4121..5434
                     /locus_tag="L1V17_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBN1236653.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            5424..6077
                     /locus_tag="L1V17_001895"
     CDS             5424..6077
                     /locus_tag="L1V17_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBN1236654.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            6132..6824
                     /gene="radC"
                     /locus_tag="L1V17_001896"
     CDS             6132..6824
                     /gene="radC"
                     /locus_tag="L1V17_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBN1236655.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            6974..7174
                     /locus_tag="L1V17_001897"
     CDS             6974..7174
                     /locus_tag="L1V17_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBN1236656.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(7428..9107)
                     /locus_tag="L1V17_001898"
     CDS             complement(7428..9107)
                     /locus_tag="L1V17_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBN1236657.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(9109..9321)
                     /locus_tag="L1V17_001899"
     CDS             complement(9109..9321)
                     /locus_tag="L1V17_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HBN1236658.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9714..11444
                     /gene="efrA"
                     /locus_tag="L1V17_001900"
     CDS             9714..11444
                     /gene="efrA"
                     /locus_tag="L1V17_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HBN1236659.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            11441..13201
                     /gene="efrB"
                     /locus_tag="L1V17_001901"
     CDS             11441..13201
                     /gene="efrB"
                     /locus_tag="L1V17_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HBN1236660.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            13296..13493
                     /locus_tag="L1V17_001902"
     CDS             13296..13493
                     /locus_tag="L1V17_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236661.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            13646..14131
                     /locus_tag="L1V17_001903"
     CDS             13646..14131
                     /locus_tag="L1V17_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBN1236662.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(14235..14828)
                     /gene="clpP"
                     /locus_tag="L1V17_001904"
     CDS             complement(14235..14828)
                     /gene="clpP"
                     /locus_tag="L1V17_001904"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBN1236663.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            15008..15535
                     /locus_tag="L1V17_001905"
     CDS             15008..15535
                     /locus_tag="L1V17_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236664.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            15626..16363
                     /locus_tag="L1V17_001906"
     CDS             15626..16363
                     /locus_tag="L1V17_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBN1236665.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            16367..17284
                     /gene="miaA"
                     /locus_tag="L1V17_001907"
     CDS             16367..17284
                     /gene="miaA"
                     /locus_tag="L1V17_001907"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBN1236666.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            17286..18515
                     /gene="hflX"
                     /locus_tag="L1V17_001908"
     CDS             17286..18515
                     /gene="hflX"
                     /locus_tag="L1V17_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBN1236667.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT         5990 a         3206 c         4027 g         5308 t
ORIGIN      
        1 cagatgcaag cttttgaaca ccgttttatt tgtctcacac ccttttcctt cctacttgta
       61 accttgctcc cgtgttagaa acatgttaca ctaaatatgt gaaattatta acaaggagcg
      121 tcgttatgcg agaaaaaaca gatacactgc caaaagcaac tgcgaaaaga ttacctttat
      181 atttacgcta cttgaagttg ctggatgact caggtataag tagaatcaaa tcaaatgagt
      241 tcagcgaaat cacccaaatt ccttctgcaa cgatccgcag agacttctcg caattaggcg
      301 agctaggcag aagcggatat ggctatgatg tcccttttct tatcgatgta ttcaataata
      361 tccttaatac taaagaagaa aaacgaatcg cattagtagg atatggaaat cttggcaaag
      421 cattgaaaca caacaatttt agaagaaatg aaaatctaaa tatcgtgtgc gtctttgata
      481 atgatccagc actgatcaat cgagtaattg atggagaaat gatctatccg attgatcgtt
      541 tcgcggagat agccaaagca aaaaatgtga cagtagcaat ctctacggta ccaagtaaat
      601 attcacaatc tgctattgat gaaattgtca aaggaaatgt aaccgctata cttaattttg
      661 cgcctgacag agtaactgtc ccagcttatg tcaatgttca atacattgat ttgacaaccg
      721 agttgcagac gcttatttac tttgatgaga attactcaga agttttttct taggaaaatt
      781 tgagtaggct tattgatctt gcgagaactc gtcgtaattc tttcaaaaat tttttagtac
      841 taaatgaagt ggttttttca cgaccacttg ttgactaaaa aaaaaaacca ttgtagaatg
      901 aagcataacg ctgaacaaga ggagtaactg gcacattcat tcttagagag agaactatct
      961 gctgaaaggt tctcaatgac aaccagtgaa ggtagcttgg gagtttctgt cttgaatgga
     1021 gtagagatag acgagtcgtg atcgttaact cacttgagag gcaataatga ttgattattg
     1081 caatttaggt ggtaccgcgt aaatcatacg tcctagaata cgaaagtatt ttaggacgtt
     1141 ttttagttta aaggaggaaa acagcatgac ggaagaaaat aacctatcaa caaaatataa
     1201 tccgcaagaa gttgaagctg gacgttatca gcattggtta gaacaagatt tgtttaaacc
     1261 gagcggagat aaaaaagcaa aaccttattc aatcgtaatc ccgcccccaa atgttactgg
     1321 aaaacttcat ttagggcatg cttgggatac gaccttgcaa gatatgctga ttcgtcaaaa
     1381 gagaatgcaa ggatatgata ctttatggct gcctggtatg gaccatgcag gaatcgcgac
     1441 acaagcaaaa gtagaagcga agcttagaga gcaagggatt tctcgttatg atctaggtcg
     1501 tgaaaagttc atcgatcaag tgtgggaatg gaaagaagag tatgcgagcc acatccgcga
     1561 acagtgggct aaaatgggct tatctttaga ttacagtagg gaacgtttta cattagatga
     1621 tggattatct gaagcagtac gtaaagtttt tgttacctta tacgaaaaag gtttgattta
     1681 tcgtggtgaa tatatcatca actgggatcc tcaagcacga acagctctat ctgatatcga
     1741 agttattcat aaagatatcg aaggcgcctt ttatcatatg agctatgaac tagcagatgg
     1801 atcaggcgta gtagaaattg cgacaacccg tccagaaacg atgttgggag atacggcgat
     1861 tgctgttcat ccagaagacg agcgttatca agcgctcatc ggcaaaaaag tgattctacc
     1921 tttagtcaat aaacaaatcc caatcattgc agatgaatat gtagatatgg aattcgggac
     1981 aggtgtagta aaaatcactc cagcacatga tccaaacgac tttgaggtag gtaatcgtca
     2041 tgatcttcca cgcgtaaatg ttatggatga tgatggtacg atgaatgaac tagcaggaaa
     2101 atatgctgga atggaacgtt ttgctgctcg taaagcaatc gtgcaagatc tgaaagaaat
     2161 cggtcgattg attaaaatcg atacgatgat ccacagtgtg ggtcattccg agcggacagg
     2221 tgtcgttgtt gaacctcggc tgtctactca atggtttgta aaaatggcgc cgttagcgaa
     2281 aaaagccatt gataaccaag aaacagatca agcagtggaa ttcttccctc caagattcaa
     2341 tcaaacgttt ttacgttgga tggaaaatgt ccatgattgg gtaatctcac gacaattatg
     2401 gtggggacat caaattcctg catggtatca caaagaaaca ggtgaaatgt atgtagggat
     2461 ggaagcacca gcggatagtg aaaactgggt acaagatcct gatgttttag acacttggtt
     2521 tagttcagct ttgtggcctt tctcaacaat gggctggcca gatacggaaa gcgaagatta
     2581 taagcgatac ttccctacta gcactttagt aaccggttat gacatcattt tcttctgggt
     2641 aagcagaatg attttccaaa gcttggaatt tactggcgaa cgtccatttg agaatgtctt
     2701 gattcatgga ttgattcgtg acgaacaagg gcggaagatg agtaaatcat taggtaatgg
     2761 aatcgatccg atggaagtaa tcgaaaagta tggagcagat gctctccgct ggttcttatc
     2821 gaatggttct gcaccaggac aagatgtccg cttcagctat gaaaaaatgg atgcttcttg
     2881 gaactttatc aacaaaatct ggaatgcttc acgtttcgtt atcatgaata tcgaaggaat
     2941 gaccgtagaa gagatcgatt tatctggaga aaaatcagtg gctgaccggt ggatccttac
     3001 tcgtttgaat gaaacgatcg aacgagtaac tgagctattt gatcgttttg aatttggtga
     3061 agcaggtcga caactgtata actttatctg ggatgatttt tgtgactggt acatcgaaat
     3121 gagtaaagaa gtactttatg gagatgatgc tgtttcaaaa caaaccaccc gtagcatctt
     3181 agtccataca cttgatcaga tcctacgttt attgcatcca atcatgccat tcgttacaga
     3241 agaaatatgg gaacatattc ctcatcaggg aaattctcta gtagtggcag aatatcctgt
     3301 tgtacgtcca gagtttgatg atgaaacagc ttctaaaggg atggaagtat tgaaagaatt
     3361 gattcgagcc gttcgaaata ttcgttcaga agtgaataca ccattgtcta aaccaattac
     3421 gttgctaatt aaaacaaacg atgctaaaat cgatcaattt ttagttgaaa atacaagcta
     3481 tatcgaacgc ttctgtaatc ccgaagagtt gacgatatca agtgagatca ctgcgccaga
     3541 tctagcgatg tcagctgttc tgacaggtgc agaaatcttc ttgccgttag caggattgat
     3601 caatattgaa gaagaaatca aacgattaga aaaagaactg gaaaagtgga caagcgaagt
     3661 aaaacgtgtc caaggaaaac tttctaatga acgttttgtt tctaacgcgc cggaagaagt
     3721 agtagaggca gagcgtgcaa aagaaaaaga ttatttagag aagcaaacgg ctgtcaaaga
     3781 acgaatcgaa agtttgcgta ctattcaata agaatagaaa aagagagtgt gaaatcagct
     3841 agctattact aaaagctagc tgattgaaca tcgttacagg aaagagtttg agcctcactc
     3901 ttagcttcga ttcataagga gatgtgacat aaattttgtc gcatctcttt tttagtctac
     3961 tcttattatg taggagaagg agggaggtgg atcatgtatc aagagtcaat aaagtagttg
     4021 ataaaatcgt tcctctctct gtttcttttc tctttgtcat acttttattt ttcttatgtg
     4081 ttctatttgt tataataaaa gagaaatggg ggaattgttg atgacgattg aagaagcaat
     4141 agaatggatc catagtcgat taccatttgg ttcacgtcct ggccttgacc gagtcgaagc
     4201 tttattagaa gtggtagggc atccagagag aaaagtaaaa acgatccata tcgctggaac
     4261 aaacggaaaa ggttctactg tagcttattt gagaagccta ttagaagagg ctgggctgac
     4321 agtaggtaca tttacttcac cttatatcga aacgttcaat gaacggatcg caatcaatgg
     4381 caaaagcatt ccagacaatg atttgatcca gcttgtaaaa aaatatcagc cactgatcaa
     4441 acaacttgat caatttgaag cagtagctgg tattactgaa ttcgagacat taacagcaat
     4501 ggcatttgat tattttttga tgaagaaagt ggacgtagcg attatcgaag ttggcttagg
     4561 cggcttattg gattctacca atgtagctgt accaatgctg acgggaataa caacgattgg
     4621 acttgatcat accgaaatac ttggagatac aattgaagaa atcgctgcac aaaaagctgg
     4681 aatcatcaaa caaggcgttc cagtagtaac aggaaatatt gccccagaag cttttactgt
     4741 catccaacaa acagctaaag caaaaaatgc accgctttat gtatacgggg aaaattataa
     4801 aataaactat ctgcatcctg atgagatgtg gggagaagta tttgaatttt ttaatgaaat
     4861 aggaaagatc cctcaattaa ccactccgct tttagggcaa catcaagctg aaaatgcagg
     4921 agtagccatc gaattgtatt ttgtttactg tcaattggaa aagctgcctt tccgagaaaa
     4981 agatgttttg aagggattga agaaatctcg atggccagga agaatggagc gtttgagtaa
     5041 cgagccatta gttgttttag atggtgccca taatacgcat gcaatgaacc ggcttgttga
     5101 gaatttgaaa aaagaattca aaggatatca aatcaacatt ttgttttccg ccttacgaac
     5161 taaaaatgtt agagaaatgc tagaacgatt gcagcaagta ccaaatgtcc atatttattt
     5221 gacgaccttt gaacatccaa aagccatcga attaagtgaa gtatcagatt tagcaagtga
     5281 gagagtatca atcgtttcat tgtggcaatt cggattagca gatatattgg aaaagatgac
     5341 aaatgaagac gtattagttg tgaccggttc actttatttc atttcagaag ttcgccattt
     5401 attaatacaa ttaggaggag atcatgaagt ataatgcagt gatttttgac atggatggtt
     5461 tgctgttcga cacagagtta gtgtattacg aagccacaca agtagtagca gacaagatgg
     5521 gttttcctta tgataaagac ctgtatttaa aattcttagg tgtttcagat gaagaagtat
     5581 gggcgaatta tcatatgatt ttctcggaat ttggcaaaac aagtgtacaa agattcatag
     5641 atgattcata ccaggaaacg cttgaacgtt tttcgcaagg agcggtacaa atgaagcccg
     5701 gtgtgttgga actcctctct tttttagaag aacatcagat tcccaaagtt gtcgcttcca
     5761 gtaaccaacg agcagtcatt gaacttttat tgaagaagaa caatctgttt gaacgatttg
     5821 agacgattgt ttctgcagaa aatgttcaac gagcaaaacc agacccagaa attttcttgt
     5881 tagctaatca gaagctaggt acagcgaaga aagaaacatt gattttagaa gattcacaaa
     5941 atggtatttt agcagcttct gcggctgaga tcccggtagt catggtacca gatctgcttc
     6001 caccatccca agaattgatc aaaaaaacag ctggggttgt ttcttcttta catgaaatcc
     6061 ctgcattgtt aaaataaaaa tccatctctt ttcgtatctt attttagata agatagaaag
     6121 gagatgtttt tttgggaaaa cgattgatca aagaagtacc tactagctct ttaccaaggg
     6181 aacgtatgga aatttatggc gcggaagctt tatcggatca ggagcttttg gcaatcttac
     6241 tgcgtaccgg tcaacaccct tatagtgtga tgtcgattgc tggaaatctg ttaaaaacgt
     6301 ttggaggact ggcctcttta cgacaggcta ctttgcatga gttagaagag attcgaggga
     6361 taggacgcgt gaaagcaatc gaaatcaaag ccttgatcga attaggtcga cgaattcaga
     6421 cggatcatga aagagcggct ccaccggttc gtaccagcta cgaattggcc cagcaattga
     6481 ttctggaaat gaaagatcac aaacaagaac atttggtttg tatttatttg gacacgaaga
     6541 atcaagtgat cttaaaaaaa acagtgttca tcggttcgct gaatcagtca gtcgctcatc
     6601 ctagagaaat tttccattat gctgtacgtt attgtgcagc aaggatcgtt ttagcgcata
     6661 atcatccttc tggtaatgtt attccatcgc agcaggatat gaattttacc aaaaggatac
     6721 aaaagtgtgg agaaatgatg gggatcactg tactggacca cttgatcatc ggacgcaaac
     6781 gatattttag tttgagagaa gaaggaatga tggaagagaa gtaagttgct ttcttgcaaa
     6841 aaaaatgaag caagtgtaca attatattgt aattttgttt gggaatagaa gttgaaacat
     6901 ctgttgcacc tctatcgtac acgagcaatg ttacaattta aattagtgct tttggcacga
     6961 ggaggatatt attatggaaa acggaacagt aaaatggttc aacgctgaaa aaggatttgg
     7021 atttatctca cgtgaagatg gaagcgacgt attcgttcac ttctcagcta tccaaggtga
     7081 cggattcaaa acattagaag aaggtcaagc agtgactttc gacgttgaag aatcagaccg
     7141 cggcccacaa gctgcaaacg ttgtaaaagc ttaattttat ctgtaaatca aattgatggt
     7201 agacatcaat ttttacgaga gaacaaagcg agtaacaaaa atacctgcca caagagacaa
     7261 tttctcttgt ggcaggtatt tttttgtatg aaaaagtaaa taaatttaag aggctatgaa
     7321 agagccacct tgtatcaagg aataagaaca aacaaaaatg gcttctcatg tttttcattt
     7381 gttttctctt atattcagga caaggtgctg atttcataac ctcttattta ttcttcatct
     7441 ggtgtcatta ccattggcaa aatcattgga tgtctttctg tacgttcgaa taagaaaggc
     7501 tgaagcgcgc cagtcatcgc ttctttcaat ttatattctg aacagtcagg tccattcaaa
     7561 cattctctta aagcgtggaa taagattcgc tgagcttcat tgatcatttc tcctgattct
     7621 cgcatgtaga caaatccacg agagagaata tctggaccag ccaagatttc ttttttcttg
     7681 atatccactg tcgcgacagc taatacaaga ccttcttctg aaagcaggtg acggtcacgt
     7741 aaaacgacat taccaatatc accgatcccg ctaccatcga tatacacatc tccagccaca
     7801 aaatgcccag caggacgcgc agaatcgcta gttaacgcta aaacatcgcc attttccatg
     7861 atgaagcagt tttctgcagg aacacctaca tcttgtgcta gagaagcatg tactttcaac
     7921 atgcggaatt ctccgtggac aggaataaaa tattttggct tcatcaaacg aagcattaat
     7981 ttttgttctt cttgtccacc gtgaccggaa gtatggatgt tattgatttt tccgtgaatc
     8041 acttctgcac cagcttcaga cagcaaattg atcaaatgat tgacacttgt tgtattacca
     8101 ggaataggtg aacttgaaaa gatcactgta tcgtctggct ggatttggat ttgacggtga
     8161 gtaccattcg cgatgcggct caacgcggcc atcgcttctc cttgagaacc tgtacatagg
     8221 atcatcgttt cattggcagg caagcgattg atttcgtgtg catctacaaa tgtgccgtct
     8281 ggaactttga tatatcctaa acgttgaccg ttgacgatgg cattttccat gcttcgtccg
     8341 aaaacagcga ttttacgacc agttgccaca gcggcatctg ctgcttgctg caaacggaag
     8401 atgttagaag caaagctggc aaaaatgata cgtccttcga tttttgaaaa gatcttcaaa
     8461 atagaatgcc caatcgtttt ttctgattta gtaaatgttg gaatctcagc atttgtacta
     8521 tcagataaaa ggcacaagac tccttcttcc ccgatacgag ccattttatg caagtttgct
     8581 ggttcgccaa caggagtgaa atcgaatttg aagtctccag tcgctacgat atttccagaa
     8641 ggtgttttca ccacgatccc taatgcatct gggatactat gggtcgttct gaaaaagctg
     8701 acagaagtct ttctaaaacg gatgatcgta tcttcattga tctcatggag ctctgcatct
     8761 cgaagcaagc catgctcatc taatttgttt gtgatcaacg ctaatgcgag aggaccagca
     8821 tagataggaa tatttgcttg tttcagcaag tagggtattc cgccgatgtg gtcttcgtgc
     8881 ccgtgagtaa tcaccaaggc ttttactttg tgtaagtttt gtatgatgta gctgtagtcg
     8941 ggaatgacat agtcaattcc aagtaaatcg tcttccggga atttgatccc ggcatcaatc
     9001 aaaatgattt catcttggaa ttgtacccca tacgtatttt tcccgatttc acctaatcca
     9061 ccaatagcaa agacgcctgt ctcgttattt ttgatggaaa gtttcatatt aaaactccac
     9121 taatgagaaa tcagcatttt ctttttcgta ctctagatga cttccttcta gaagttgaac
     9181 gaattcaata ttgtatgggg tattttcttc cacacgttgg cgagcgtcta catcgctttt
     9241 tgcctcaatg taaagagatt ttgtttcttc ccgtttaggg ttgcgtactt ttgtttcttg
     9301 ataataaact ttatagatca ttgttttgtc tcctttatct gcgtaaagca gtgatttagc
     9361 tagttgattt ttttagacaa cacaaaacga ggggacaagc cacctggttt ttcatatgct
     9421 ttgactagaa tactggattc gagtcaaaga gacaagcctc gtttttgctt atctgttcgg
     9481 atattttttc aaccgtacct tctgtataaa aaatatacaa caattaattg ttattctagc
     9541 ataaaacagc aaataagtat agaaatcaac tagattgaaa gaaaaaatca atgtttatca
     9601 tcccgctata atcataatga cttttttatg agagaagtgt tctattaata ggctcgttgt
     9661 gctatcattt ttagtaatga aaatgtaaca aaagattaaa aggagatgag aaagtgaaac
     9721 taatgtggca ttataccatg cgttataaga aattcttgtt tttcaatttc atatgcgtat
     9781 ttggttttat tttgattgaa ttaggacttc ctacgatttt agcacgtatg atcgatgtag
     9841 gaatccgcaa tgatgatttt gattatgtga agcaacaagg gatatttatg atcgttatta
     9901 ctgtaatcgg tattattttg aatatcttgt taggttattt tggttcgagg attacgacta
     9961 atatcgtagc agatattcga gatgatttgt tcgaaaagat ccaaagttat tcgcatcagg
    10021 aatacgaaaa tctaggcgta tcttcattga tcactcgtac aacaaacgat gcttatcaga
    10081 tcatgttgtt cctgcaaaat attttacgta tcggttttat ggcaccaatg atgttcattg
    10141 tcagtttgta catggtcatg cgtacaagtg tgacactcag tttgtatgta gtaggtgcat
    10201 tacctttact attattggca gtcgtagcga ttgctaaggt gtctgaaccg ttatctaaaa
    10261 agcaacaaaa aaacttagat aaaatcaaca gtatcttgcg ggaaaatctt tcaggattgc
    10321 gtgtgattcg tgcattcgtc aatgaaaagt ttgaagaaaa acgttttgct gtagtcaatg
    10381 agaattatgc ttctagttca aaaagcttat tccgtttgat ggctgttgca caaccgggtt
    10441 tttatttctt atttaatatc gtaatggtat tgatcatctg gagcggggca gtgcaaatcg
    10501 atgcaggcga gcttcgtgta ggagatttga ttgcgtttat cgagtatata ttccatgcct
    10561 tgttctcatt catgttattt gctagtgtgt tcatgatgta tccaagagca gctgtttcag
    10621 ctggacgtat ccaagaagcc ctagatgcca aaccttcgat tgtagaagat ccaaatggta
    10681 tatctgatac aaaaactaaa gggtatatcg aatttcaaaa tgtaacattt gcttatccag
    10741 gccattcgca agagccagtg atacgaaatg tcagttttac agcctctcca ggagagaccg
    10801 ttgcttttat tggaagtacc ggtagcggaa aatctacgtt gatccaattg atccctcgct
    10861 tttatgatgt gagtgaagga aagatcttga tcgatggagt agacgtgaga gattatcggc
    10921 taagcaagtt gcgagataag attgggttta ttccgcaaaa agcgctgcta tttactggaa
    10981 cgattgcaga taatttgcga tacgggaaag aagatgctac gcaagaagaa atggaacgtg
    11041 cagctgagat tgctcaagct tcagaattca tttctcgaaa accagatgga tttaatgaac
    11101 atttatcaga aggtggttcc aatttttcag gtggacaaaa acaacgattg gcaatagcca
    11161 gagccatcat acgccgtccg gaaatctata tttttgatga cagcttttct gcattagatt
    11221 atcaaacgga tgcgaagtta cgtgctcgtc tgaaaaaaga aacgacagaa tctactgtat
    11281 tgatcgtagc acaacgtgtg ggaacgatca tgcatgcaga taagatcatc gtattaaatg
    11341 aaggagaagt cgtcggtatg gggacgcatc gggagttgtt ggaaaaatgc ccgatttatt
    11401 atgatattgc cgcttctcaa ttatcaaagg aggaattagc atgaaaaaaa ccttttcttc
    11461 cttaaaacgt ttagctcgat atatcagacc gtatcgtgag acttttcttt tagtgatcct
    11521 atttacagtt ctgacagtgg ctttcaacgt ggctttgcca tatgttacag gacttcctac
    11581 tacagaaatc agccgtaata ttgccaatgg cgaatcaatc aatttttctt atatattcaa
    11641 atgtctcatt tggatcacag ttgttggaat agggtattgt atttcgcaat tactttctgg
    11701 tgttttgatg acaaatgtcg ttcaaagtgc catgcatgat ttgagaagag acatagaaga
    11761 aaaaatcaat cgtcttccgg tttcatattt cgataaaaac cagcaaggaa atattttgtc
    11821 tcgtgtgacg aatgatgtag atgcagtcag cggtgcttta caacaagctt ttattggtat
    11881 cgtaaatgcg atattgggaa ttacgttggc tgcagcaatg atgttttata tccagccgat
    11941 gatggcgctg atctctatga tcatgattcc aacatcgatc tggatctcaa aacgagtgat
    12001 caatgcttcg cagaaatatt ttcaaagcat gcagaattct cttggtgagc taaacggcta
    12061 cgtccaagaa aatatgacag gttttagtgt attgaaagta tatggacgcg aaaaagaaac
    12121 attggaagga ttcaaaaaag ttaatcacag cttgaaatac tttgggtttc gtgcagcatt
    12181 catttctggc ttgatgatgc ctctagttca attaactgcc tatgctactt atattggtat
    12241 ggctgttcta ggaagctttt atgttattac tggggcgatc gttgtcggtc aactacaagc
    12301 attcatccaa tatatttggc aaatcagtca gccaatgggg aacgtgacac aattgtcttc
    12361 agttttgcaa agtgcatcag cggcaacgaa acgtgtattc gagattttag atgagccaga
    12421 agaaaaagaa aacaaagtag atgcttcact gccagaaacg attttaggag atgtgacatt
    12481 cgatcatgtc gattttgcat atgatccgaa gaaaccatta atccaagatt tgaattttga
    12541 agtgaaagct ggtcaaaccg tagctgtggt cggtccgacc ggtgccggca agacgacatt
    12601 gatcaatcta ttgatgcgtt tttatgacgt agacaaagga gcaataagga ttgatggaat
    12661 cgacaccaaa tcaatgagtc gcagtgatgt gcgttcgcta tttggtatgg tcttgcaaga
    12721 tgcatggctt tatcaaggaa cgattgcaga taatatccgc ttcggaaagc ttgatgcgac
    12781 agattatgaa gtagttgatg ctgcgaaaac agcaaacgta gatcatttta tccgaacgat
    12841 gccagatgga tatgatatgg ccatcaattc tgagggagac aatgtgtctt taggacaaaa
    12901 acagttgctg acgattgccc gagcagtggt ctccgatcct aaaatcttga ttttagatga
    12961 agcaacaagt tcagtagaca cccgtttaga agcgttgatt caaaaagcaa tggatcgcgt
    13021 gatggaggga cggacaagtt tcgtcatcgc tcaccgttta tcgacaatcc gtgatgcaga
    13081 tctgattcta gtgatggatc aaggtcagat cattgaaaaa ggaacgcatg agagtttatt
    13141 ggcacaaggt ggattttatg aaaaactgta taacagccaa tttgctgagg aagcagaata
    13201 agtcatataa gaataaaaca gtttaaaact tattttttgt tctctattct tgataatggt
    13261 aaagtaaagt tatcaagaaa agtgaggaca cggagatgga acagttttta aatgaaaaaa
    13321 ttactgaagc caaaagagaa gttgatcgtt taacgcacgt ctgtcagacg aagccttttg
    13381 attcagctga tttttttgaa aatgagtttc aaatcgaacg cttggcagca caaatagaag
    13441 tgtacgaatt aattttaaaa aaagtaatag aagaaaatat agatgtacaa taaaaacagg
    13501 taaaacgtca gttaccagat actgtaaata gacatctggc ctgagcaggt tttacctgtt
    13561 ttttttctta tgaaataaat atatgctatg atacctttat tcaataggat tagtttctac
    13621 aaaaaatgaa aggagaaaaa taaatatgga acggtttata gcatcaaatg ccacagtgat
    13681 tggtgatgtg acattgtcag aagatgtgac gatctggtat caagctgttt tacgcgggga
    13741 cagtaattgg ataaaaatag gacaaagaac gaatatccaa gatggtacaa tcatccatgt
    13801 cgatcatgat gcacctgtag atattgcgga gaatgtgacg gtaggacatc agtgcatgct
    13861 acatggctgt acaatcgaaa aaggggcgct gatcgggatg gggaccacga tattgaatca
    13921 tgcggttatt ggtgagaata gtttgattgg tgctggatca ttagtaacag aaggaaaagt
    13981 tattcctcct aatgtcttgg cttttggtcg cccagctaaa gtgatccgtc ctttgacaaa
    14041 agaagaaata caaaaaaaca aagaaaacat ccagcattat gtcgagatag gtcggatgca
    14101 tgcgcaagga aaattcaagg agcaaagata ggcagtagca tccataaaat aaaaaaggat
    14161 ggtcagtttg agttgaccat ccttttttat ttggtttaga taagagagct taaaaaagct
    14221 tcctttgaaa cagattaatt taatgaagaa ctgttttcca tgacttcatc gatcaatcca
    14281 tatgcttttg cttgttcagc tgtcatatag ttgtcacgat ctgtatcttt ttcaatcact
    14341 tcaagcggtt gtccagtgcg ttcagctaaa attttgttta agcgttcgcg tgtttgcaaa
    14401 atatggcgtg ccgcaatttc gatttcagtt gcttgccctt gagcgccgcc aagaggttga
    14461 tggatcatga tctcagcatt tggtaaagca aatcgtttac cttttgtacc agctgtcagc
    14521 aagaagcttc ccattgaagc agccataccc ataacaattg tttggacatc tgctttgaca
    14581 aagttcattg tgtcgtaaat agccatacct gctgtaactg aaccaccagg agaattgata
    14641 taaagataga tatctttttc agaatcttga gcgtctaaga aaagcaattg ggcgatgatc
    14701 gaattagcaa gatcatctgt tacttggccg cttaacatga tgatacggtc tttcaataaa
    14761 cgtgagtaga tatcgtaagc tctttcacct cgtgaagatt gttcaatgac tgtaggaatt
    14821 aaattcataa tagagttcct ccttgatttc gtttagaaat agtgtaccat aatttagttt
    14881 ctaataccta aaatgtagta tacatttttg gtcaaaaaag gtcaaataaa aaacttaggc
    14941 aaattagtcg cataaacccg ctttatggta tgataagcag agaaacaaaa caaggaggaa
    15001 caacagattg atagttggta ttactggcct tatcggagtg ctgacaggtg ctgtagttgt
    15061 ctatatcggc atgatactgc aaatgcgtca cttggaaaat aaagaacagc gtagacgtga
    15121 attggaattg aaagtcaaag aaatcgagac gctgaatcaa ttaaataaaa agatcaacga
    15181 gatcttgcaa aaacggacaa cgctgatgga agaatatgtc agctttgatg catttgatga
    15241 ttgttatatc acgattgacg attttgcgta tctccaatca ttttcagcgc aaaatagttt
    15301 ttatctgcca aattatattt tagacgagct atttaagaat atctcccatc gaaaagtgat
    15361 tttatctcca gatgaaacaa tgaagattgg tggatatgct tataaaggcg gacgcgtgat
    15421 tttagagaat tttacggata gtctgactga aatgatcaat gaaaaaaaag ctcagttgaa
    15481 gactatgacg cgccagccga ttggtttctt ctcgaaagat gatgtttgga gctgatattt
    15541 tgaagcattg ccgttgcaca tgagagcgtg gtaatgcttt ctttttttct taatgataca
    15601 atagaactga acggagtgaa gaaagatgtt acaaatctat gcccatcgcg gaagcagcgg
    15661 cacccaccca gaaaatacgc ttcctgcatt tgcagaagct gtacgagtag gtgcagatgg
    15721 tatcgaacta gatgtccatc taagcaaaga tggttatttg atcgttatgc acgacgaaga
    15781 agtggaccgg acgactaacg gtaaagggct gattcgagaa aaaacattgg aagaactcaa
    15841 aaaattgaat gcagggggca aattcagcaa agaatttcca gcagctaaag ttcctgaatt
    15901 gagagaagtg ttaggactgc tcctccaaaa aaattaccga gggatgctaa tgattgaaat
    15961 taaaactgat cagtatgaat atcccggtat cgaagaaaaa ttagccgaaa cattaaaaag
    16021 tagagattgg ccttttcaac atgcatattg cagctttcat ttggattctt tggaaaaaat
    16081 cgcattactg gaaccggaga tacagctgga cttattgatg agtacttctg ataaaaagat
    16141 ccaactagca gcagaaaccc cttatataga aggagtacat ccaaaaaata cttggttgtt
    16201 cgaacatcca gtccaggcag ctgattttcc aaaagcaatt cgtgcatgga cgattaacga
    16261 tgaagaagaa atggccaaat gtcaagaact caaaatagat ggaataataa ctgattttcc
    16321 ggagaaagct cttcggtgga aacaatcaac gaaaagtagg taaaatatgg aaaaagtatt
    16381 agtgatcgtc ggtccgacag cagtcggtaa aacagcgcta agtgtggaac tcgcacaact
    16441 atttggagga gagatcatca gtggtgattc attgcaaatc tataaaaatc tggatatcgg
    16501 tacagcaaaa atcaaagaag aagagatgaa taatgttccg catcatttga ttgatgtgat
    16561 cgaacctact caacgttact cagccgctga ttttcagcat tcaggtcgac aattgattac
    16621 cgagattgcg aaccgagggc acctacctat catagctggt ggtacgggtc tctatatcca
    16681 atcccttcta tatgattatc agttaggagc gacagaagaa gcgaatcctg agattagaaa
    16741 aaagtatgaa acgttagctg aaacaattgg ttcccaagca ttatggaatc agttgaaaga
    16801 aaaagacccg gcagctgctg agaaaatcca ctggaacaat caacgcaaag tgataagagc
    16861 tctggaagtt ttagagacga caggacatag tatcacggca cctaaagaag agccaaagca
    16921 attgtatgat tacctcatga ttggattaga tacgaagcgt agtattcttt atgaacgaat
    16981 caatcaaaga gtcgatttga tgctagcaga aggtttagta gcagaagcgc gtaaggtgta
    17041 tgagcttgga gaagtccagg ccagtcaagg tattggatat aaagaatttt tcccttattt
    17101 tgaagggaaa gaaacattgg aagaagcaac agaacaagtc aaactacatt cgagaagata
    17161 cgcgaaacgt cagttgacgt ggtttcgtaa ccgtttggat gcacagtggt ttgatcttat
    17221 aagtgagcca aatcaaaaaa gtcagattga gcaaacaatc aaaaaatggc tggaggcgga
    17281 ataaaatgga agaaaaagtg atcatcgtag gggtagaaac cgaagcaaac cagcgttact
    17341 tttcagagtc aatggaagag ctagttcagc tgacgaatac cgcatcagga gaagtcgtat
    17401 tcacaattac acaaaagaga ccacaagtgg atcggcaaac gattatcggt aaagggaaat
    17461 tacaagaatt agttcaacaa gcggatgcgc atgaagcgga tttgatcatc tttaatcatg
    17521 agctaactcc gagacagagc caactgatta ccgatgctgt tggtcttccg gtaattgatc
    17581 gcgtgcagct tatcttagat atttttgcga tgcgtgctcg ttcgaaagaa gggaagctgc
    17641 aggttgaact tgctcagtta gaatacctgc tgcctcgttt agtagggcaa gggaaaacat
    17701 tatctcgtct tggcggtggg atcggaacaa gagggccagg tgaaacaaag ttagaaacag
    17761 accgccgaca tatacggaat aaaatttttg ctgttaagaa agaattgaaa gaagtagaag
    17821 ctcatcgaga gcgcaatcgc caaaaaagaa aaaatagcga gatttttcag attggactta
    17881 ttggctacac gaatgccggg aagtcaacta tcttgaatct attgacacaa gcggatactt
    17941 attcgaaaga tcaattgttt gcaacgttag atccattgac taagagatgg cgttttgctg
    18001 aaggatttga gattactgta acggataccg tcgggttcat ccaagacctg cctacgcaac
    18061 tgatcgatgc tttccattct acattagaag aaagtcaaaa tatggatctt ttgctacatg
    18121 tagtcgatgc tagttctcca gatcgtattt tacaggagca gactgtctta aaattgatgg
    18181 atgaactgaa tatgaaagaa atgccgatac tgactgttta caataaggca gaccagatcg
    18241 acccagcgat gttcacgcct acgctattcc caaatgtatt gatttctact cagacgaaag
    18301 aaggtaagat ggcgttgatc gaagcaatca aacgtcagct gatggaacta atgacccctt
    18361 atacactttc tgtgccaagc aacgaaggac agaaattaag cgagttgaga agacaaacaa
    18421 tggttttgga cgaagcgtac atggaagaaa caaacgaata tgaagttaaa gggtttgcaa
    18481 aaaccaattc aaaatggtta agaaaaaacc aataaaattt tattttttta a
//
LOCUS       DAFLWC010000060        18330 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.061, whole genome shotgun sequence.
ACCESSION   DAFLWC010000060 DAFLWC010000000
VERSION     DAFLWC010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18330
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.061"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            21..542
                     /locus_tag="L1V17_001909"
     CDS             21..542
                     /locus_tag="L1V17_001909"
                     /inference="COORDINATES: protein motif:HMM:NF024252.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1236668.1"
                     /translation="MHIGDKIHKLRRLNNETMNDLVKQTGLSKSWVSDIESGKKQRAD
                     FNKICAIAKHYKVSLEYFQDDYLDSDEHEDIIPLTDETRVKSVKSLEQSLKYLNNKQE
                     PNLLEIKLKDTDSVPEVYYKGQKLEGLIDVSYHYHTTTDVVAGSTNDINMEYLGEVTK
                     YPDIKTIGHKRDV"
     gene            543..860
                     /locus_tag="L1V17_001910"
     CDS             543..860
                     /locus_tag="L1V17_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBN1236669.1"
                     /translation="MKEARPRDEIDKLYKTKRWRDLRQVVIARDFGMCQECKRRGRNT
                     RGTIIHHIVEAREDLSLFWSVDNLECICVACHNREHPERSGGKKKPKPKSHIVKMYST
                     PER"
     gene            complement(1017..1181)
                     /locus_tag="L1V17_001911"
     CDS             complement(1017..1181)
                     /locus_tag="L1V17_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzC family protein"
                     /protein_id="HBN1236670.1"
                     /translation="MGELYKPGEDNKPKGTYKEVGPRGGNVQGGREVKIDPGDRLPPT
                     SQKGNKWTKK"
     gene            1284..1805
                     /locus_tag="L1V17_001912"
     CDS             1284..1805
                     /locus_tag="L1V17_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HBN1236671.1"
                     /translation="MPQPAKSAKLQLLNGNPNKKNTEELRKRAAAEDKLKMATDKIKP
                     PLWLDSLGKDTFEFIADELLSVDLISNPDVHTMALYSNWYSQYVSLEKQLRKLQREYK
                     LNYALAKKEAEARGEPFNEPNELIGNPLSRQMDTASRNLRSFGADLGLSPAARAKLAI
                     KMADDGGDDDDDF"
     gene            1792..2265
                     /locus_tag="L1V17_001913"
     CDS             1792..2265
                     /locus_tag="L1V17_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003666010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HBN1236672.1"
                     /translation="MTTSNILDMSYTERVDYWQSYLEEQASWGGFLKCPYPELLTTWY
                     AERLIDGSIPASKENIQAAKRHMRDLQRQGTDDFPWIFDEEKGHRPIRYIEKKCKPTE
                     GDFGSFVLQPWQHFIIGSMYGWVHRDTGERRFREALIFVGRKNGKFCRLKIGQNR"
     gene            complement(2272..2430)
                     /locus_tag="L1V17_001914"
     CDS             complement(2272..2430)
                     /locus_tag="L1V17_001914"
                     /inference="COORDINATES: protein motif:HMM:NF024064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix domain-containing protein"
                     /protein_id="HBN1236673.1"
                     /translation="MDKYGLKNRIRISNAIDKDLYEGLKKMSEETMVPMSKLLDKAIE
                     LLLKESQK"
     gene            2523..3284
                     /locus_tag="L1V17_001915"
     CDS             2523..3284
                     /locus_tag="L1V17_001915"
                     /inference="COORDINATES: protein motif:HMM:TIGR01453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBN1236674.1"
                     /translation="MKKYIIYKHLNKINGKIYIGVTNDIGRRWRSGGIEYKPPKNETQ
                     HHRSFWNAIQKYGWENFDHLIIEEDLTMKEAFEKEKFYIELYDSTNKKKGYNIAKGGN
                     GGIIYKVHPKGMLGKKQSKEFSSNHSKWAKNHKNNCMTNGDVVWGVTHEHPKGMLGKH
                     HSKESIMKKKAYSGENAVTSKPIVAIERDGTKREFHSAKLCMAYYSISTCVFYRLLKD
                     GAPYVINPKANYRNKEKILAIEGIMFKHKEDTEVS"
     gene            3504..4823
                     /locus_tag="L1V17_001916"
     CDS             3504..4823
                     /locus_tag="L1V17_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003666013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBN1236675.1"
                     /translation="MVAYDDEQGANVYVLANARDQASLLFDKAAEMVKQSPALFKKFG
                     KPKRSSINYAPAFSKMEPRASDSRKLDGLNTHFGIFDEIHEFTNYNLINVIKKSRGTR
                     KQPLIVYITTAGYVLDGPLMSYFEQGVDCLEHLEDDIDERTFYYLAKLDSAEEADDPR
                     LWIKANPNICLMNFVGMLDDYVKDKKDPKEYADWITKQFNLFSDIDELSFVDMPTIKR
                     NNKTIDIETLKGKKCVGGFDLSETEDFTAAVLEFPLETGEVFILQHTWIPQARFDRDN
                     NQERIKAWEKVGDLTIIPGDYVNYEYVLNWFVENSKIYDIVKINYDKAKALRLNKELE
                     NAGFETNEIRQGFLSLGGPMQNFKEMLLDGKVIFNNSKLYRWYLSNVKLVMDRNSNWM
                     PSKQSKSRKIDGFAASLNSHAEVLNMLVNPVGTGKVTYYSISDLMNM"
     gene            4839..6059
                     /locus_tag="L1V17_001917"
     CDS             4839..6059
                     /locus_tag="L1V17_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBN1236676.1"
                     /translation="MSILDRLRSFGRAKPKASKQEYFLNDPGLIPYLVGKDEISEGIF
                     SVISRVSNVFASLPLKMIDAEFGQPDDCPAYNLLSEGPRYFTKFDFFRDVEVLRNYQG
                     NAYVQIFRNINGEVADMALIKPGACHPVIDMDSGELYYQVTATDKGSYKQVIYVHYME
                     MLHFKQPRFGGLEGTDPTKVLTNTLGYDREVRKISLSQLKGGNEGLKVKFASNVDEEA
                     KKATVKNIADFYRQNGGLLVEENGVEIERLQRELVDSKLLDTDKVSRSRIAMVYNVPE
                     HFIGSNQSSYSSQEQLNMEFLTYNLVPTVNQYEAELNKKTLSRTEKAKGYRYKFNVAS
                     LLRADTQARGQFYQIMRRGGAYSANDVRRFEDLQPINKTGMDDYHISGDLYPIDMDPT
                     LRKTNSSKSVAENG"
     gene            6094..6771
                     /locus_tag="L1V17_001918"
     CDS             6094..6771
                     /locus_tag="L1V17_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HBN1236677.1"
                     /translation="MKKVTLSGDVVDNDTAWLYDWFGIDCISPGKISAALTEAAGDEV
                     ELDISSNGGDVLAASEIYTAIRAYPGKVSGNVVSIAASAASVIACACEPLRISPTAHI
                     MIHNAWVTTSGNAEELKANAEMLSSVDESIVNAYEIKTGLDRKKLADLMAKDTWLNAQ
                     TAVAEGFADEIMFAEAPVTVLNASQPVIPKNAVTKLKNLILKAETPQEETLLQKKLKA
                     LNGGKNE"
     gene            6768..7964
                     /locus_tag="L1V17_001919"
     CDS             6768..7964
                     /locus_tag="L1V17_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBN1236678.1"
                     /translation="MNLEQLKNAWVEAGSKVSDLNAQLNAALVDDEKTEEDVVSLQAQ
                     VKAARAKRDGLKEQVANMEAEQVLNVKKEPLDKKDENLKNKFIKDFKAMVNGDPAIMA
                     TLTSNTDESGNAIGLTIPVDVQTTIHTLVRQFDSLQEYVNVEKVTTTSGSRVYEKWSD
                     INPLTALDTEDGEIPANDDPALYLIKYLIKRYAGISTVTNSLLKDTAENILAWLSNWI
                     AKKVVVTRNTKILAAIDGIKAAQKKDVTDVDGIKDIINVQLDPAIEATSMFITNQDGF
                     NVLDKVKRADGSYLLQKDVASATGYTFLGKPIKKIASRFLPNKGTQATPKYPLYIGDL
                     KEAVTLYDRENMSLLTTNIGGGAFETDTTKVRVIDRFDVQLVDDEAVVLATFTSIANE
                     VPVTNG"
     gene            7979..8302
                     /locus_tag="L1V17_001920"
     CDS             7979..8302
                     /locus_tag="L1V17_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBN1236679.1"
                     /translation="MILDPKMDLDEIKNALKIDTDDDDVEVRRAVQAAIAYIRGAIGN
                     DKPSFYKQENDTVDLINLAILQLADHYYNARSATVSGNLREYDLGFTSLILQLKARYL
                     LFVEE"
     gene            8306..8641
                     /locus_tag="L1V17_001921"
     CDS             8306..8641
                     /locus_tag="L1V17_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBN1236680.1"
                     /translation="MPLIQTGNLNQRIKFVRDTTVKDEDGQVVRTSTTILTCWASVQT
                     QRLNDIKTSIGTALEGTLTFIIRYQQKSELTNDMKVRWNGKTFEIITITKGEFAKDFT
                     TIIAKEVSK"
     gene            8638..9033
                     /locus_tag="L1V17_001922"
     CDS             8638..9033
                     /locus_tag="L1V17_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236681.1"
                     /translation="MSVEVDATEVYKALREVKANVQRVESPALRKAGEYAQEKLQQNT
                     PYWDGTKSNGKRGSYMQEHAKDHVVTSSVKNGLIEVGYDKDVSWRMHFIEFGTIKQRP
                     KGFVQKTQKQIEKQVTQIIADEVKRRLGL"
     gene            9030..9401
                     /locus_tag="L1V17_001923"
     CDS             9030..9401
                     /locus_tag="L1V17_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236682.1"
                     /translation="MKTAVSQVYSILNSNEKTKNIDFYTNSVPESAQTVPSLPVGRIT
                     EIFGNYEDFASNNPLTIQFNVQVDVWVSTLKEVDAFYFALDEIMRGNGWQCAYTEQTD
                     DEDLEGAKRIIKRYVANISLN"
     gene            9417..9977
                     /locus_tag="L1V17_001924"
     CDS             9417..9977
                     /locus_tag="L1V17_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBN1236683.1"
                     /translation="MATVGFESVIFGVKTGAGGTLKELVADKSKGGAIEAKITGLGAT
                     SNTTYASNVPFFIASKGVSSPKVTLDVADLMDNGIYSEIIGAKTVDGVNVIGSETEAP
                     YVSVVMVTANKEGKRLFMGLAKGKFSHPDIDMKTAEDKGVELQTDSIEGEFISDERGY
                     VYLTAVESEEMTLQKFKDLVNNKAGE"
     gene            10104..10415
                     /locus_tag="L1V17_001925"
     CDS             10104..10415
                     /locus_tag="L1V17_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236684.1"
                     /translation="MIELQLKLDGKKKTFKQQDISARAMRECIKFYEKAEKADLTDLE
                     AIDSMIAITADIFQDPAVTFDAILDGLTASELVPALESVFEQINELGNNEKKQTASKK
                     R"
     gene            10439..10630
                     /locus_tag="L1V17_001926"
     CDS             10439..10630
                     /locus_tag="L1V17_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236685.1"
                     /translation="MDQIYKDLIESGWTMRDVDEADYHYLLHLFGEVESGEEYVDGAD
                     FIKQFLSAEDLVKLEEGGK"
     gene            10630..14475
                     /locus_tag="L1V17_001927"
     CDS             10630..14475
                     /locus_tag="L1V17_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBN1236686.1"
                     /translation="MAGKGQPAGNIKLGISLDSTNFGNTLDEINAKVKQAESNMRANL
                     KAYDSAGRSYEALSQKTKDLSTVMEGQNAKVRELTKRRDEAISKYGEESKQVANLNTQ
                     INNATAKYNAYSRQLNDTKKELVYSKTAVNDLSNEIKENERQMNAEVKALKAAGDESG
                     AFEAKQKGLAKQTELSEKAIEEQRKVVKLMADEFGDSANETEDAKRALEKLERQSQIS
                     SRQLEALKSSSDQSGKKIEDFGDKSTRSARKLDGLKDKLGSLKSAFSFGAVAGLAHNA
                     ISSVVSGVQGLVGEAVNASDSLMKFSKTMEFANFGKSQIESSKKEMKDYADKTVYGLE
                     EILNTTAQLASNGIPNYTELTKAAGNLNAVAGGSSDTFKSVAMMLTQTAGAGKLTTEN
                     WNQLADAIPGASGLLQDAMLKNGAYTGNFRDAMAQGQITSDEFNQAIVQLGMNDGAVK
                     AATSTDTLSGSWEQMKSTVINGLQSIIDKVGVENITGFINRVTKGIENSIPKITQFIG
                     WLRDIGTWIVENREPLTWIVGIIGGITLAVKALNVASMLLAITGGTLAAPFVAIGVAL
                     GALAGALVIAYTKSETFRNIVNAAFTAVKNVVMSVINNLVEYYKMLWSVLQWLWEKIK
                     EWASWIGNKFIEMKNSVVNTVQNLWNGVKNFFSNGVGDTWNKVVGWVKNIFNKATELK
                     NKVSDAIGNLWNGIKDTFRRGIDTVFNWFSELPTKMKNAIIGGKNAIVDAFKSIFNAA
                     LKAIGKPVNAIIHGASWVLEKLGADKLEEWKVPQYAKGTPNGGHPGGPMMVNDGRGAE
                     AVITPNGQAFIPRGRNVVLNAPKGTHVLTAEETAYMTGNKAPRYRYAKGTGFFGNLWN
                     NVKGFAGDVGNKLKDVVGDVWDFVTDPGALARKVLNGLGVLEGLVKYPLDVGKGILSK
                     ATEALTNKITELFSSGSLDTSMGMQGVYKYLADVAVAVMKKFPGFVATSGYRPGDPYS
                     HGKRNAIDIALPGVTGGSPRYTEAANYAFEKFANKIGYVITNGKVRDRSGQSGTGIHN
                     DWRPWPDGDHYDHVHLNGVKDPQNTQISGDSVGGSGVERWRNVAIRALKMTGQYSTAN
                     LNALLNQMRTESNGNPNAVNNWDINAKNGTPSKGLLQVIDPTFRQYAMPGFNSNIFDP
                     LSNILASIRYALSRYGSLTNAYRGVGYANGGIVNQHQIAEIAEGNKPEIIIPLDKAKR
                     SRAMQLLSIAMDKLGVSPKTYGNATTVSSDYEILEAIEKQAATTNQLLSLLLAFFKGN
                     SRTDRDLALDIQKILVRRM"
     gene            14476..15348
                     /locus_tag="L1V17_001928"
     CDS             14476..15348
                     /locus_tag="L1V17_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate protein"
                     /protein_id="HBN1236687.1"
                     /translation="MRTVLLRNRINEEIDLSTEDYFATGLSNMGFEVKKEHVGQWGNF
                     RESSENVEISEFQSSVIISVHGFREKELYNSLVQFLSEGPFELEFAFDGETMVRRCSL
                     KSLSKTEIDPKTSLLTDTLELYFTSNWYSVKREKLIQRPNVVKTRGKVFPYKRSYIYT
                     QNLWEKKGVFKFNNNSVYLTNSKERMSPLKIRVIGKCSNPYWEVIQNSQIIATDGYFI
                     DMTETQTLEVSSLFEDTTAILKDIAGVESSVYQQQDYTKTNFVQAPTGEFSIVFHVGG
                     ADVEIELYEERDLF"
     gene            15345..16394
                     /locus_tag="L1V17_001929"
     CDS             15345..16394
                     /locus_tag="L1V17_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236688.1"
                     /translation="MILAVTLFHRDLMLYNEHLFSNSFEFGADEINEEASSFTMDKYV
                     PVKTGDFLLAKYIPSGKFAYFGVITSQEDEKISCKSLLSLADSEIPTARVSGDNYEEH
                     IRRLIEYYLLNDPTKQLKDILDVKAESATSHSYQATDTNKHKLSAYILNGFKKYNVKW
                     YFKGIQNRKIYTGIRAVNESIYIKDNSSEFSDWDVFVQAPGAGNENKLLIVDKAMKDI
                     EKPIILSTWYLDEENNLTQDGSKENITKPTVNLVNIYDQTAEDKASYEDVAKSELKGN
                     TYSHEIKVNVVRNAKNLNVETIETGMFATISYKGKIYKSVLTAWRISSDKEFVELTFG
                     NIRSRFMDYFEDNGG"
     gene            16398..17222
                     /locus_tag="L1V17_001930"
     CDS             16398..17222
                     /locus_tag="L1V17_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236689.1"
                     /translation="MVSNVDGYQFENVKVSAENDARLYHVLYNRKNQVIDGYDQSMNL
                     SSSGLTVKVAAGAAIIQGRMVVVRQEESITVPANSSGYIALTVDLTQEVIPGSILPES
                     EEYEWTNNQVKLEFITKVIKGNLNNGDKVYNLPLCSVTSTGSTVSISKISDSYELTLS
                     KGEILWSGTALMHDTQTVQPSKKMWQTVSGFLLVWLPYENGQAIGDRYVTTPFYKERV
                     TFTNVLGEIVSGFDDYHKKWFSKRINYNSNTNIFTGAASNASGDNANMVLRYIVSF"
     gene            17240..17785
                     /locus_tag="L1V17_001931"
                     /pseudo
     CDS             17240..17785
                     /locus_tag="L1V17_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176405.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
BASE COUNT         6339 a         3150 c         4129 g         4712 t
ORIGIN      
        1 tggattaagg aggaagagta atgcatatag gagataagat acataaattg agacggctta
       61 ataacgaaac aatgaacgac ttagttaaac aaaccggact gtcaaaatca tgggtatctg
      121 atattgagtc tggaaaaaag caacgcgctg actttaataa gatatgtgca atagccaaac
      181 attataaagt tagcttagaa tactttcagg atgattattt ggatagtgat gaacacgagg
      241 atattattcc tttgacagac gaaacaagag ttaaatcagt gaaatcgctt gaacaaagcc
      301 taaagtatct gaataacaaa caagaaccta accttctaga gatcaaacta aaagatactg
      361 actcagtacc agaggtttat tacaaaggtc agaagttaga gggattgata gatgtaagct
      421 atcactacca tacaacaact gatgtggtag ctggttcaac aaacgacatc aatatggagt
      481 acctaggtga agtaactaag tatccagata taaaaacaat cggacacaag agagatgtgt
      541 aaatgaaaga agctagacct agagacgaga tagacaaact atacaagacc aaacgatggc
      601 gagacctaag gcaagtagta atagctaggg acttcggcat gtgccaagag tgcaagcgtc
      661 gagggcggaa cacaaggggc acgatcatcc atcacatagt cgaggcgagg gaagacctgt
      721 cactgttctg gtccgtagat aaccttgaat gtatctgtgt agcttgtcac aacagagagc
      781 atccagagag atcaggcggg aagaagaaac caaaacctaa atcacatatc gttaaaatgt
      841 attcaactcc tgaaagataa gtttgcagcg aaatgaaggt agccccccta ctctaaaaga
      901 ttaaagagta aggcttgaga agaacggtgc tgtccttcct tcgtaaaaag accgcttttc
      961 aagttttttg gagaaaaagg aaaaagccga ccaatttaag ccggctttgg acgaagctat
     1021 ttcttagtcc atttgtttcc tttttgagaa gtaggaggta atcggtcgcc tggatcaatt
     1081 tttacttctc gtccgccttg gacatttcca ccacgaggtc ccacttcttt ataggttcct
     1141 tttggtttat tgtcttcgcc gggtttatag agttctccca taggaatccc tccctaaaaa
     1201 aatttcggca cagcactgcc gataacttaa ttataaggat tgtgataacg atttcaatat
     1261 atcttttgaa agaaggtgat attatgccgc aaccagcgaa gagtgcaaaa ttacaattat
     1321 taaacggaaa cccaaataag aagaataccg aagaactccg caagcgagcg gccgcagaag
     1381 acaaattaaa aatggctact gacaaaatca aaccgccgtt atggctagat tcgctaggaa
     1441 aggatacctt tgagtttatc gctgatgaat tgctgtctgt ggatttaatc agtaatccgg
     1501 acgtccatac aatggctctc tactccaatt ggtattcgca atacgtttct ttagaaaaac
     1561 agcttcgaaa actacaacga gagtacaagt tgaactatgc gcttgcgaaa aaggaggcag
     1621 aggcgagagg tgagccgttt aatgaaccta atgaattaat tggtaatccg ctctctcggc
     1681 agatggatac agcgtcgcgg aatctccgtt cttttggcgc tgatttagga ctatcaccag
     1741 cagccagagc taagttagct attaagatgg ctgatgatgg tggtgatgac gatgacgact
     1801 tctaatattt tggatatgtc ctacacagaa cgtgtggact attggcaaag ctatcttgag
     1861 gagcaagctt cttggggtgg ctttttaaaa tgtccatatc cggaattgtt aactacttgg
     1921 tatgcggaac gattaatcga tggaagcata ccagccagca aagaaaatat tcaagctgct
     1981 aaacggcata tgcgtgattt gcagcgccaa ggaacagatg attttccttg gatctttgac
     2041 gaagaaaaag gtcaccggcc tattagatat atcgaaaaaa aatgtaaacc aactgaaggc
     2101 gactttggtt cgtttgtttt gcaaccttgg cagcatttca taattggatc catgtacgga
     2161 tgggtacatc gtgatacagg agagcgtcgc ttccgcgagg ctcttatttt tgttggacgt
     2221 aaaaacggta agttttgccg tttaaaaatc gggcaaaatc ggtgaaaacc tttatttttg
     2281 gctttctttt agtaataatt cgatagcttt atcaagcaat ttagacatag gaaccatagt
     2341 ttcttccgac atttttttta atccttcgta taaatcttta tcaattgcgt tagaaattct
     2401 aattctgttt tttagtccgt atttgtccat gtgtgacact cctttttatt ttactataac
     2461 atccgattcc accgcttgca actaccatca attgatggta gtatataaaa gaggtgagta
     2521 gattgaaaaa atacattatt tacaaacact taaataaaat aaatggcaaa atttatatcg
     2581 gtgtcacaaa tgatattggc agaaggtgga ggagcggtgg gattgaatat aaaccaccaa
     2641 agaacgaaac ccaacaccac agaagttttt ggaatgcaat acaaaaatac gggtgggaaa
     2701 attttgatca tttgattatt gaagaagact taacgatgaa agaagctttt gagaaagaaa
     2761 agttttatat tgaactttat gactcaacta ataagaaaaa aggttataac atcgcaaaag
     2821 gcggaaatgg cggaataata tataaagttc accccaaagg aatgctaggg aaaaaacaat
     2881 ctaaagaatt ttcttcaaat cacagtaaat gggcaaagaa ccataagaat aattgtatga
     2941 caaacggtga tgttgtatgg ggtgttactc acgaacaccc aaaaggcatg ttgggaaagc
     3001 accacagcaa agaatcaatt atgaaaaaga aagcatatag tggtgaaaat gctgtaacct
     3061 caaaaccaat tgtcgcaatt gaacgggatg gaactaaaag agaatttcac agcgctaagc
     3121 tttgcatggc ttactattcg attagtacat gtgtttttta ccgactttta aaagatggcg
     3181 ccccttatgt gataaatcct aaagcgaact acagaaataa agaaaaaata ttagctatcg
     3241 aaggaattat gttcaaacat aaagaagata ccgaggtaag ttagtagatt gcgaaaggtt
     3301 actaactacc gtaacgcgta ggagttgaat aaatataatg ctcccaagag tgtccgacag
     3361 cagataattt gctgaaaatg tacgctaaac tgggccagaa ctgactgacc gatgaaaatg
     3421 agggtgacct ccagagtgcg agataaaaag ctcgcagata ataacaatcg aaaacatcac
     3481 taatttcagg cctttccaca tacatggtcg cttatgatga tgaacaaggc gccaacgttt
     3541 acgtattggc aaatgctcgt gatcaagcaa gcttgttgtt tgataaggcc gcagaaatgg
     3601 tcaaacaatc gccggcgctc tttaagaaat ttggtaagcc taaacgatca agtattaatt
     3661 atgctcccgc cttttctaaa atggaaccac gcgcctcaga tagccggaaa ttggatgggc
     3721 taaacactca ctttggtatt tttgacgaga tccacgagtt tacgaattac aatctgatca
     3781 acgttatcaa gaaatcaaga ggaaccagaa aacagcctct gatagtttat atcacaactg
     3841 ctggatatgt attagatggt ccgttgatgt cttattttga gcaaggtgtg gactgtttgg
     3901 aacatttgga agatgacatc gatgaacgga ctttctatta tctggcaaaa cttgacagtg
     3961 cggaagaggc tgatgaccca agattatgga tcaaagccaa tccgaatatt tgtctaatga
     4021 attttgttgg catgctagat gactatgtta aggataaaaa agatccaaaa gaatatgctg
     4081 actggattac caagcaattt aacttgtttt ccgatatcga tgagctgtca tttgtcgata
     4141 tgcctaccat taaacgaaac aataaaacca tcgatattga aacgctcaaa ggtaagaagt
     4201 gtgtcggtgg ttttgacttg tccgaaacgg aagactttac cgcagccgtt ttagaatttc
     4261 cgcttgaaac aggcgaggta ttcattttgc aacacacatg gatcccacaa gctagatttg
     4321 atcgagataa caatcaagag cgtatcaaag cgtgggagaa ggtgggagat ctaacgatta
     4381 ttcctggtga ttacgtcaat tatgaatacg tcttaaattg gtttgtagaa aattcgaaaa
     4441 tctatgacat tgtaaaaatc aattatgaca aggccaaggc gctacgatta aataaagaac
     4501 tagaaaatgc aggatttgaa accaacgaga ttcggcaagg gtttctatca ttaggtgggc
     4561 caatgcaaaa cttcaaggaa atgctattgg acggtaaggt gattttcaac aattccaagc
     4621 tttaccgatg gtatctatcc aacgtcaagc tggtgatgga tcgcaactca aactggatgc
     4681 cgtctaagca gtccaagagt agaaaaatag atggttttgc agcaagtttg aacagccacg
     4741 ccgaagtgtt gaatatgttg gttaatcctg tcggaaccgg gaaagtaacc tattactcga
     4801 tttccgattt aatgaatatg taagaaaggt gtggaggaat gagtatttta gatcgtttgc
     4861 gttcttttgg ccgagcgaag ccgaaagcga gcaaacaaga gtattttttg aatgacccgg
     4921 gattgatacc gtatttagtc ggaaaagatg aaatatcaga agggattttt tccgtaatta
     4981 gccgtgtatc gaacgttttt gcgtctctcc ctctcaaaat gatagatgcg gagtttggcc
     5041 aaccggacga ctgtcctgca tacaacttgt tgagcgaagg ccctcgatat tttacaaagt
     5101 ttgatttttt ccgggacgtg gaagttttga gaaactacca agggaatgcg tatgtgcaga
     5161 ttttccgaaa tatcaatgga gaagtagcag atatggcgtt aataaaacct ggtgcttgcc
     5221 atccagtgat tgatatggat agcggggagc tttactacca agtaactgcg actgacaaag
     5281 gcagttataa gcaagttatt tatgtacatt acatggaaat gctccacttt aaacaaccga
     5341 ggtttggtgg cttggaaggt acagacccca caaaagtatt aacgaatacc ctcggatatg
     5401 atcgagaagt ccgaaaaatc tctttaagtc agcttaaagg aggtaatgaa gggctaaaag
     5461 ttaagtttgc tagcaatgtg gatgaagaag ctaaaaaagc tacagttaaa aacattgctg
     5521 atttttatcg acaaaacggt ggactacttg tggaagaaaa cggtgtagaa atcgaacgtt
     5581 tacaacgaga gctggtagac agcaagcttt tagatactga taaagtatct cgctccagaa
     5641 tcgcgatggt ctacaacgtg ccggaacatt tcattgggag taaccagtcg agttactctt
     5701 cacaggaaca gctcaatatg gagtttttga catacaatct agtaccgacc gttaatcaat
     5761 atgaagcgga actaaataag aaaacactat cgagaaccga aaaagcaaaa ggttatcgat
     5821 ataagtttaa tgtcgcaagt ttgctaagag ctgacactca ggcaaggggg caattctatc
     5881 aaatcatgcg acgaggcgga gcatactcag cgaatgatgt ccgaagattt gaggacttgc
     5941 aaccgataaa taaaaccggt atggatgatt atcatatttc cggagaccta tatccaatcg
     6001 atatggatcc aacattaaga aaaacaaact cgtctaaaag cgtagccgaa aacggttagg
     6061 cttttttagt ttgcaccgaa gggaggtgaa aggatgaaaa aagtgacgtt aagcggcgat
     6121 gtcgtggata acgataccgc gtggttatat gactggtttg ggattgattg tatctcacca
     6181 gggaaaattt ctgccgctct tacagaagca gcgggggatg aagtagaact tgatatctca
     6241 tctaacggtg gggatgtcct agcggcaagc gaaatatata ccgctatccg tgcctatccg
     6301 ggaaaggtat ccggaaatgt tgtgagtatt gcagcaagcg ctgcaagtgt aatcgcttgt
     6361 gcttgcgaac cgcttagaat ctcgccaaca gcacacatca tgattcacaa cgcatgggtg
     6421 accactagcg gcaacgccga ggaattaaaa gccaatgcgg aaatgttaag cagtgtggat
     6481 gagtctatcg ttaatgctta cgagatcaag acaggactcg accggaaaaa gcttgctgat
     6541 ttaatggcaa aagatacttg gttaaacgca caaacagcag tggcggaagg ttttgcggat
     6601 gaaattatgt ttgcagaagc accagtaacg gtactcaatg cctctcaacc ggttattcca
     6661 aaaaacgcgg taactaagtt gaaaaatcta atactcaaag cggaaacacc gcaagaagaa
     6721 acgctcttgc agaaaaaact aaaagcctta aatggaggga aaaacgaatg aatttagaac
     6781 aattaaaaaa tgcgtgggtc gaggcgggaa gtaaagtctc tgatttaaac gcgcaactca
     6841 atgcagcatt ggttgacgat gaaaaaacag aagaagatgt agtaagtttg caagcacaag
     6901 taaaagcagc acgggctaaa cgggacggat tgaaagagca agtggcaaat atggaagccg
     6961 aacaagtctt aaacgtcaaa aaagaaccat tagataaaaa agatgaaaac ttgaaaaaca
     7021 agtttatcaa agactttaaa gcgatggtca atggtgatcc tgctattatg gctactttga
     7081 catctaatac ggatgaatct ggtaatgcta tcggattgac tattcctgta gatgtgcaaa
     7141 cgactattca tactttggtt cgtcagtttg actctttgca agaatacgta aacgttgaaa
     7201 aagtgaccac tactagcggt tctcgggttt atgaaaaatg gtctgatatt aacccactga
     7261 ccgctttgga tactgaagac ggtgaaatcc cagcaaatga tgatcctgca ctttacttga
     7321 tcaaatactt gatcaaacgc tacgcaggta tttctacagt aactaacagc ttgctaaaag
     7381 atactgccga aaacattttg gcatggttgt ctaactggat cgcgaaaaaa gtagttgtta
     7441 ctcgcaatac aaaaatcttg gcagctattg atggaatcaa agcagcgcaa aagaaagatg
     7501 ttacagatgt tgatgggatt aaagatatca taaacgtcca acttgatcca gctatcgaag
     7561 ctacatctat gtttattaca aaccaagatg gcttcaatgt tttagataaa gtgaaacgtg
     7621 ctgatggatc ttacttgtta caaaaagacg tagcttctgc aactggatat accttcttag
     7681 gtaaaccaat caagaaaatt gcttctcgtt tcttgccaaa caaaggtacg caagctactc
     7741 ctaaatatcc actgtatatt ggtgatctga aagaagctgt tacattgtat gatcgcgaaa
     7801 acatgagctt gctgacaacg aatattggcg ggggggcttt tgaaacagac accaccaaag
     7861 tacgggttat cgatcgattt gatgtgcagt tagtcgatga tgaagcagtt gttttagcta
     7921 catttacatc tatcgcaaac gaagtgccag taacaaacgg ttaaggagct gatttcttat
     7981 gattcttgat cctaaaatgg atttagacga aatcaaaaac gcactaaaga ttgataccga
     8041 tgatgacgat gtggaagtaa gacgtgcggt gcaagctgca attgcataca ttagaggggc
     8101 tatcgggaat gataagccct ctttttataa gcaagaaaat gacacggttg atctgattaa
     8161 tttagctatt ctgcaattag cagatcatta ttacaacgct cgatcagcaa ccgtgagtgg
     8221 gaacttgcga gagtacgatt taggttttac aagcctaatc ttgcaactca aagcaagata
     8281 tttgcttttt gtggaggagt agcgtatgcc ccttattcaa acaggaaatt taaatcaacg
     8341 catcaagttt gtccgagata cgacggtcaa ggacgaggac gggcaagttg tccggacttc
     8401 tacaaccatt cttacttgct gggcaagtgt gcagacacaa cgcctgaacg atattaagac
     8461 gtccattggt acggctttgg aaggaacact gacgttcatt atccgctatc aacaaaaatc
     8521 agagctaacc aatgatatga aagtgcgttg gaatggaaaa acgtttgaaa tcattacgat
     8581 tacgaaaggc gagtttgcga aggacttcac gacaatcatt gcaaaagagg tttcaaaatg
     8641 agtgtagaag tcgatgcaac cgaagtgtac aaagcgctta gggaagtaaa agcaaacgtt
     8701 caacgagtgg aaagcccagc acttagaaaa gctggggagt acgctcaaga aaagttacaa
     8761 caaaacacac cttactggga tggaacgaag tcaaacggta aacgtggttc gtatatgcaa
     8821 gaacatgcta aggaccatgt ggttacaagc tcggtaaaaa acggattgat agaagtcggc
     8881 tatgataaag atgtttcttg gcggatgcac tttatcgagt tcggaacaat caaacaacgt
     8941 ccaaaaggtt tcgtacaaaa aacacaaaag caaatcgaaa aacaagtaac acaaatcatt
     9001 gctgacgaag taaaaaggag gctaggactt tgaaaacggc agtatcacaa gtctattcaa
     9061 ttctgaatag caatgaaaaa acaaagaaca ttgattttta caccaatagt gttccggaat
     9121 cggctcaaac agtacctagc cttccagttg gcagaattac agagatattc ggcaactatg
     9181 aagatttcgc aagcaacaat cctttgacca ttcaatttaa cgtacaggta gatgtatggg
     9241 tatcgacctt aaaagaggtt gatgcctttt attttgccct tgatgagatt atgaggggga
     9301 atggttggca atgcgcatac acggaacaaa cagatgatga ggatttagaa ggtgcaaagc
     9361 ggattatcaa acgatatgta gcaaatattt cactaaatta aaaggagaga aaatagatgg
     9421 caacagtagg atttgagagc gtcatttttg gcgtaaaaac aggtgcaggc ggcactctaa
     9481 aagaattagt agcagataag tcgaaaggcg gagcgatcga agctaaaatt actggattag
     9541 gcgcaacttc taacacaaca tacgcttcaa acgtaccatt cttcattgca agtaaagggg
     9601 tttcgtcgcc aaaagttacg cttgacgtgg cagacttaat ggataacggc atttacagcg
     9661 aaatcattgg cgctaaaacc gtggatggtg taaatgtaat tggttcagaa actgaagcgc
     9721 cttacgtgtc ggtagtcatg gttacagcga acaaagaagg aaaacgctta ttcatgggat
     9781 tggcaaaagg aaaattcagt catccagata tcgacatgaa aacagctgaa gacaaaggag
     9841 ttgaattgca aaccgattct atcgaagggg aattcatttc tgatgaacgt ggctatgtat
     9901 acttaacagc cgtagaatca gaagaaatga ccttacaaaa attcaaggac ttggtaaata
     9961 acaaagcggg ggagtagtta accctgcatc tacaccaacg acagatacag ggacaccaaa
    10021 agaaccagaa ccaaaaattg atacacaagg ttagccattt tttggctagc cttatttttt
    10081 tgtaaaaaca aggaggaaaa caaatgattg aattgcaatt gaaacttgac ggaaagaaaa
    10141 aaacattcaa acaacaagat atttccgcac gtgcaatgcg tgagtgtatc aaattttacg
    10201 agaaagcgga aaaagcagac ctaactgatt tagaagcaat tgattcaatg attgcaatta
    10261 cagcagatat tttccaagat ccagcagtta catttgatgc tattttagac ggtttgactg
    10321 cgagcgagtt agtaccggca ttagaaagtg tttttgaaca aatcaatgaa ctgggaaaca
    10381 atgaaaaaaa gcagacggcg agcaaaaaga gataagtttt tctgaagcta ggaaagcaat
    10441 ggatcaaatc tacaaagatt taatcgaatc aggttggacg atgagagatg tggacgaagc
    10501 cgactatcat tatttgttac acctttttgg agaagtggag agtggcgaag aatatgtaga
    10561 tggtgctgat ttcatcaaac aatttttatc ggctgaagac ttggtaaaac ttgaggaagg
    10621 aggtaaataa tggcaggaaa aggacaaccg gcaggaaata tcaagctagg gattagttta
    10681 gatagcacta attttggtaa cacgctggac gaaatcaatg cgaaagtcaa acaagctgag
    10741 tcgaatatgc gtgccaatct aaaggcttat gattcagcag gacgttcata cgaagcactt
    10801 agtcaaaaga cgaaagactt gtctacggtt atggaagggc aaaacgccaa agtaagagaa
    10861 ttaacaaagc gccgtgatga agcgattagc aagtatggcg aggaatcgaa acaagttgct
    10921 aaccttaaca cacagataaa caatgctacc gcaaaatata atgcttacag tcgccagttg
    10981 aatgacacaa aaaaagaatt ggtgtattcc aaaacagccg tcaatgattt atctaacgaa
    11041 atcaaagaaa atgaacgaca aatgaacgcc gaagtaaaag cgttgaaagc cgctggtgat
    11101 gaatctggtg cgtttgaagc aaaacaaaaa gggctagcca aacaaacgga attatccgag
    11161 aaagctatcg aagaacagcg caaagttgtg aaactgatgg ctgatgagtt tggcgattca
    11221 gcaaatgaaa ccgaagatgc aaaaagggca ttagaaaagt tagaacgaca aagccaaata
    11281 tctagcaggc aattagaagc actcaaaagc tccagcgatc aatcaggaaa aaaaatagaa
    11341 gattttggcg acaagtccac aaggtcagct aggaaactgg atgggctaaa agacaaatta
    11401 ggctcgctaa aaagcgcatt ttcgtttggt gcagttgctg gattagcgca taacgctatt
    11461 agcagtgtag taagtggcgt gcaaggcttg gttggcgaag cagtaaacgc atcggattca
    11521 ttgatgaagt tttccaaaac catggagttt gctaactttg ggaagtcaca gatagaaagc
    11581 tcgaaaaaag aaatgaaaga ctacgccgat aagacggttt atggtttaga agaaattctg
    11641 aacacaaccg cacaattggc atctaacggg attcctaact atacagaact aaccaaggcg
    11701 gcaggtaact tgaatgccgt tgcaggcggt tctagtgata cattcaaatc cgttgccatg
    11761 atgctaacgc agacggcagg agctgggaaa ctaacaactg aaaactggaa tcaattagca
    11821 gatgcgatac cgggcgcttc agggctgtta caagacgcta tgttgaaaaa cggagcttat
    11881 acaggaaact tccgtgatgc aatggcgcaa ggtcaaatca cttctgatga gtttaaccaa
    11941 gcgattgtac agttaggtat gaatgacgga gcagttaaag cagctacttc cacagataca
    12001 ttgagtggtt cttgggaaca gatgaaatct actgtaataa atgggttaca aagtatcata
    12061 gacaaagtag gcgttgaaaa tatcactggt ttcatcaaca gagtaacaaa agggattgaa
    12121 aattctattc ctaaaattac tcaatttata ggttggttga gagatattgg aacgtggatc
    12181 gttgaaaata gagagccact aacatggatt gtcggaatca taggcggaat tacattagca
    12241 gtaaaagcat tgaacgtagc aagtatgttg ctggcaatta ctggcggaac attggcagcc
    12301 ccttttgtgg cgattggtgt agcattaggc gcactagcag gtgctttggt gatagcttat
    12361 acaaaatctg aaacatttag aaatatagtc aatgcggctt ttacagctgt gaaaaacgta
    12421 gttatgagcg ttatcaataa tttggtggaa tactacaaaa tgttgtggag cgtgttgcag
    12481 tggctttggg aaaaaataaa agaatgggct tcatggattg gcaataaatt cattgaaatg
    12541 aagaacagcg ttgtgaatac ggttcagaac ctatggaatg gtgtgaaaaa cttcttcagt
    12601 aatggcgttg gagacacttg gaataaggta gttggctggg taaaaaacat tttcaacaaa
    12661 gcaactgaat tgaagaacaa agtttctgat gcaattggta acctgtggaa cggtatcaaa
    12721 gacacattcc gtagaggcat tgatacggta ttcaattggt tttcagaact accgacgaag
    12781 atgaagaatg ccattattgg cggtaaaaat gccattgttg atgcgttcaa aagtattttc
    12841 aacgcagcac ttaaagcgat aggtaaacca gttaacgcaa tcatccatgg agcttcatgg
    12901 gtactagaaa aactgggtgc tgacaaactc gaagaatgga aagtgccaca atacgcaaaa
    12961 ggaacaccaa acggaggtca tccgggcggg cctatgatgg taaatgacgg tagaggtgct
    13021 gaagcggtaa tcacacctaa cggacaagca tttatcccac gagggcgaaa tgtagtgttg
    13081 aatgcaccaa aaggcacaca cgttctaaca gctgaagaaa cagcttatat gactggaaac
    13141 aaagcaccaa gatatagata cgccaaaggt acaggctttt tcggaaatct atggaacaac
    13201 gtcaaaggat ttgctggaga tgttggaaac aagctgaaag atgtagtcgg cgatgtatgg
    13261 gattttgtaa cagacccggg agcgttggct aggaaagtgt taaatggtct tggcgtactg
    13321 gaagggcttg tcaaatatcc tttagatgtt ggtaaaggta ttctaagcaa ggctaccgaa
    13381 gcattgacga acaaaatcac agaactattc agcagtggca gtttagacac ttcaatgggc
    13441 atgcaaggcg tttacaaata cttggcggac gttgcagttg cagtaatgaa gaagtttcca
    13501 ggctttgtgg caactagtgg gtatagacca ggtgacccct attcgcatgg taaacgtaat
    13561 gccattgata ttgcactacc tggtgtcaca ggaggctcgc cacgctacac agaagcagcc
    13621 aattacgcat ttgagaagtt tgcaaacaaa atcggctatg ttatcacaaa tggcaaggtt
    13681 cgtgaccgtt caggacaatc aggtacaggt attcacaatg attggagacc atggcccgat
    13741 ggagatcact atgatcatgt gcatttaaac ggtgtgaaag acccacaaaa cactcaaatt
    13801 tcaggagata gcgtgggagg cagtggggta gaaagatggc gcaatgtagc aattagagcg
    13861 ttgaaaatga ccggtcaata cagtactgca aacttaaatg cattactaaa tcaaatgcgt
    13921 acagagtcaa atggtaatcc taatgcagtt aacaattggg atattaacgc caaaaatgga
    13981 acaccatcaa aagggttgct ccaagtgatt gacccaacat tcagacagta tgcaatgcca
    14041 ggattcaaca gcaatatttt tgacccacta tctaacatct tagcttcaat cagatacgca
    14101 ctatcaagat atggctcact aacaaatgcc tatcgtggag ttggttacgc aaacggtgga
    14161 attgtaaacc aacatcaaat tgcggaaatc gcagaaggaa acaagccaga aattattatt
    14221 cctttagata aggctaaacg atcaagagcg atgcaattat tgtctatcgc aatggacaaa
    14281 ctaggagttt ctcctaaaac ttatggaaat gcgacaactg tttccagtga ttacgaaatc
    14341 ctagaagcca ttgaaaaaca ggcggcaaca acgaatcagc tgttatcgtt attgctggca
    14401 tttttcaaag gaaatagccg aactgataga gatttagctt tagatattca gaagatcttg
    14461 gttaggagga tgtagatgcg aactgtatta ctgagaaata gaataaacga agaaattgat
    14521 ttgtctacgg aggattattt tgctactggg ttgagtaata tggggtttga agtaaaaaaa
    14581 gaacatgtgg gacagtgggg gaatttcaga gaaagcagtg agaacgttga aatatctgaa
    14641 tttcagtcat ctgtaatcat ttctgtgcat gggtttcgag aaaaagaact gtacaattca
    14701 cttgtgcagt tcctatcgga aggtccgttt gaactggaat ttgcttttga cggcgaaaca
    14761 atggtaagaa gatgcagtct aaaatcttta agtaagactg aaatcgatcc gaaaacatcg
    14821 ttactaacag acactttaga actatatttc acatcaaact ggtattccgt aaaacgcgaa
    14881 aaattaattc agcgaccgaa tgtagtgaaa acacgtggta aggtttttcc gtataaaaga
    14941 tcttatatct acactcaaaa cttgtgggag aaaaaaggtg tattcaaatt caataataat
    15001 tctgtatacc taacgaatag caaggaacgg atgtccccgc taaaaattcg tgtgattggg
    15061 aagtgttcaa atccgtattg ggaagtaatc caaaactcac aaatcatcgc aacggatgga
    15121 tacttcatag atatgactga aacacagact ctagaagtat caagcctttt tgaagataca
    15181 acggcgattt taaaagatat tgcaggggta gaatcttctg tctaccaaca acaggattat
    15241 acaaaaacta attttgttca ggccccgact ggagaattca gcattgtgtt tcatgttggg
    15301 ggggcagacg tagagattga gttatacgag gagcgtgatc tgttttgatt ttagcagtca
    15361 cgctttttca tcgtgattta atgctttata acgaacattt attctctaac agttttgaat
    15421 ttggtgcgga cgagatcaac gaagaggcta gtagctttac gatggataag tacgttcctg
    15481 taaaaacagg cgattttcta ctagcaaaat atattcctag tggaaaattt gcatattttg
    15541 gtgtaattac gtcgcaggaa gacgaaaaaa tcagttgtaa aagcttactt agtttagctg
    15601 atagtgagat accgactgca cgtgtgtcag gagataacta cgaagagcat atccggcggt
    15661 tgattgaata ctatttgctg aatgatccaa cgaaacaact aaaagatatt ttagacgtca
    15721 aagcagaaag tgcgacctct cattcgtatc aagctaccga tacgaataaa cacaagttaa
    15781 gtgcgtatat tctcaatggt ttcaaaaaat acaacgtaaa atggtatttc aagggaattc
    15841 aaaacagaaa aatctataca ggcatacgtg ctgtaaatga atcaatttac attaaagaca
    15901 attcttctga atttagcgat tgggatgtgt ttgttcaggc gccgggcgct ggaaacgaga
    15961 acaagctatt aatcgttgat aaagcaatga aagatataga gaaaccgata atactgtcaa
    16021 catggtattt ggacgaagaa aacaatttga cacaagatgg atcgaaagaa aatatcacga
    16081 aaccaactgt caatttggtt aatatctacg atcaaaccgc agaagataaa gcatcctacg
    16141 aagatgtggc aaaatcagag ttgaaaggca atacgtattc gcatgaaatc aaagtgaacg
    16201 ttgtaagaaa tgcaaaaaat ttgaatgtcg aaacgattga aacagggatg tttgccacga
    16261 tttcttataa aggaaagata tacaagtcgg ttttgacagc ttggcgaata tcaagtgata
    16321 aggagtttgt ggaattgact ttcggaaaca taagaagtcg ttttatggat tattttgaag
    16381 ataatggggg ataaaaaatg gttagcaatg tggatggata tcaatttgaa aacgtgaaag
    16441 taagcgcaga aaatgatgct agactttatc acgttttata taatcggaaa aatcaggtta
    16501 ttgatggtta cgatcagtct atgaatttat cttcaagcgg attaacagta aaagttgctg
    16561 caggagcagc gattattcaa ggtcgtatgg tcgttgttcg acaagaagaa agtataacag
    16621 ttccagcaaa ctcaagtggt tatatagcat taacagtgga tttgacacaa gaagttatac
    16681 ctggatctat tcttccagaa tcggaagaat atgaatggac taataatcaa gtcaagctag
    16741 aatttataac aaaagttata aaaggtaatt taaacaatgg tgataaggtc tataatttac
    16801 cactatgctc agttacttct actggatcaa ctgtttcaat ctcaaagata tcggatagtt
    16861 acgagctgac tctctctaaa ggagaaattt tgtggagtgg gactgcgtta atgcatgata
    16921 ctcaaactgt ccaaccttca aaaaaaatgt ggcagacagt ttcaggtttt ttattagtat
    16981 ggctcccata cgaaaacggg caagcaattg gggatagata tgtaactacg cctttttata
    17041 aagagcgtgt aacttttact aatgttttag gagaaattgt ttcaggattt gatgactatc
    17101 acaaaaagtg gtttagtaaa cgaataaact ataattcgaa tactaatata tttacaggtg
    17161 cagcaagcaa tgcaagtgga gataacgcaa atatggtgct taggtatata gtttcttttt
    17221 agttaggagg tatggaagag tggcaaattt agaaattaaa ttatctgcaa ataagagaca
    17281 gccttatcta cgtcaccgtg ttgttggtag agttggtgat ggggggctca caacaatcaa
    17341 tgtacaactt cttgaggaag atgaaattac accttttgta attaatctaa acggtacttt
    17401 gaaatttgtg ggcgaagttt caaacggtaa ctataccgag ggagaaccag aaataatcga
    17461 ttcgactaat gggttaatta gttacacgtt cactaagtca aatttcagca cgagtcatca
    17521 attcaaacaa gcatattttg aatatgtaga tcctaacggc aaaaaagtaa cttttcagaa
    17581 cttcatcata gacgtgttag aacgagtaga tattaattcg gagcaagcga aatactatat
    17641 ttcttcattg gaaaaattac agagtgaaat gcaaaccact ttcaatcagt tcattagtga
    17701 taaacaggtc caatacgatc aaatctactc gaaatataac gaattagtaa gattgataaa
    17761 tgaatcagat aagcaagtaa atgatcgtat tgataagaca aatgatcgta ttgatcaaac
    17821 caatcagcaa atcggcgatc tcggcaagct gaaaaagatg tacagtaaca gcatcgactt
    17881 cggggactat gattatagtg ggaatccgaa ccttagcgct aaacttaatg cttcaagttt
    17941 ttctttaggt actggcgcaa cagtcgcgga tgataatgat gagattgtgt ttaccttaga
    18001 tggcacaaat caactatcga agtacgctag caaagcgcaa gtgccggtag cagaagggaa
    18061 acaatatacg attagttgtg aaattatgtt agaagatggg ttcactggcg acccttcagg
    18121 aatacgtctg caacacgcat atttgccagg cggggttgtt gttttacaga cagagacagt
    18181 acctaaaaat gaattgaata cgtggcagac gcttatcgga acgcgaacgg taaaatacac
    18241 ctctgacgta ccaaatgaat ggtacccttt gtttagagac atccgaacac ttaaaccgac
    18301 cggtaaagtt agactaagaa aaattaagat
//
LOCUS       DAFLWC010000061        17444 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.062, whole genome shotgun sequence.
ACCESSION   DAFLWC010000061 DAFLWC010000000
VERSION     DAFLWC010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17444
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.062"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(106..651)
                     /locus_tag="L1V17_001932"
     CDS             complement(106..651)
                     /locus_tag="L1V17_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBN1236690.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(663..1355)
                     /locus_tag="L1V17_001933"
     CDS             complement(663..1355)
                     /locus_tag="L1V17_001933"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBN1236691.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(1374..1658)
                     /locus_tag="L1V17_001934"
     CDS             complement(1374..1658)
                     /locus_tag="L1V17_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236692.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(1671..2234)
                     /locus_tag="L1V17_001935"
     CDS             complement(1671..2234)
                     /locus_tag="L1V17_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBN1236693.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            2462..3124
                     /locus_tag="L1V17_001936"
     CDS             2462..3124
                     /locus_tag="L1V17_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBN1236694.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            3248..4444
                     /locus_tag="L1V17_001937"
     CDS             3248..4444
                     /locus_tag="L1V17_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBN1236695.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(4545..5921)
                     /locus_tag="L1V17_001938"
     CDS             complement(4545..5921)
                     /locus_tag="L1V17_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1236696.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(5958..6825)
                     /locus_tag="L1V17_001939"
                     /pseudo
     CDS             complement(5958..6825)
                     /locus_tag="L1V17_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
     gene            complement(6914..7939)
                     /locus_tag="L1V17_001940"
     CDS             complement(6914..7939)
                     /locus_tag="L1V17_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBN1236697.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(7957..8631)
                     /locus_tag="L1V17_001941"
     CDS             complement(7957..8631)
                     /locus_tag="L1V17_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1236698.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(8815..9708)
                     /locus_tag="L1V17_001942"
     CDS             complement(8815..9708)
                     /locus_tag="L1V17_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBN1236699.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(9782..11479)
                     /locus_tag="L1V17_001943"
     CDS             complement(9782..11479)
                     /locus_tag="L1V17_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBN1236700.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(11472..12785)
                     /locus_tag="L1V17_001944"
     CDS             complement(11472..12785)
                     /locus_tag="L1V17_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBN1236701.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(12785..16821)
                     /locus_tag="L1V17_001945"
                     /pseudo
     CDS             complement(12785..16821)
                     /locus_tag="L1V17_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
     gene            complement(16834..17292)
                     /locus_tag="L1V17_001946"
     CDS             complement(16834..17292)
                     /locus_tag="L1V17_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBN1236702.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
BASE COUNT         4904 a         3907 c         3020 g         5613 t
ORIGIN      
        1 tttttttaaa ataacgtata aaaaagagca taaaacaaag tcgtttgttt tatgctcttc
       61 ttttattatt ttgtgctttt tattttatca aatcactttg tttttttata aaatttctgc
      121 gcctagtgtg gactcaaaat gtctcaatgc ccattcatgt ccaacgggat cgaaacttgc
      181 cacggaatct ttgaaaatat ggagtttgta tcctagatta tacgcatcga ctgctgtatg
      241 caacacacag atatctgtac atacgccggt caaataaata tctgtgatct ggcgttctcg
      301 caaacggatg tctagatctg ttccactaaa agcggaataa tgccgtttgt ctatccaata
      361 aacattttcc tcttgctcat agtcttggta taaacttttt aaagagccgt acaattcccg
      421 tccacccgtt cctatcacat tatgcggagg aaataagcgg ttctccggat gaaaggaatc
      481 ttttggatca tgcgcatcaa tggcaaaaac gacaaaatcc ttttgatcaa taaacttctt
      541 tgtatgagca gtcagctttt tttcaattac ttgtcctgct gtcccagtag tcagctttcc
      601 atcctctgca acaaaatcat atgtgtagtc aatcgagatc aatgcgttca tcttagtcct
      661 ccttatacga gatgtttgac aaattcgatc accatttctg ctgatcgttt gcctgcgtct
      721 tcgataaatt cgtcaaagct ttgtgtcgcc gagtgatctg ctgtgtcgct cattgcacgt
      781 acgatcaaaa atgggatatt gaactgacga gctgtttgtc caacagcggc tccttccatt
      841 tcgcaagcta atgcttcagg gaaattcgtt aagatttctt tgattttatc tggcgagtcg
      901 acaaatgtat cacctgtaac gatcaatcct tcttttgcgt tcaaattcgt tgcttttgct
      961 gctttaacca tttcactgcg caaatatgtg cttgcttcat aatatagagg cattcctggt
     1021 aattgtcctg ggttgtagcc aaatcctgtt gcatctgcat caaaataagc tactttgtct
     1081 gatataacga tgtcacctac ttgtaagcct tcaccgattc cgccagctga acctgtattg
     1141 atcaccatgt tcacgccgta ttgttggatc aacagacttg tggtaataga tgctaagact
     1201 tttcctatac cggaacgtac gacgatcact tcgtggttac ctaatgaacc tgaaataaat
     1261 aaagcgcctg cgcgttccca tgataatggt tcgcttaggt tctctctcaa aatttttact
     1321 tcttcttcca ttgcgccgat aataccgatt ttcatctttt taattccttc tttctatata
     1381 aatgcgattg ctaaaaaaac cacacataac attaggataa caataataag agatttcatc
     1441 aaaaaagagt tccatttggt cgtcttttcc cgttcgctga tccttgtttt cgtgattggt
     1501 ttattctttt tgctttcttt acgataaaag ctggcaatct ttttttcttc ttgctgataa
     1561 gctgtttctg cttttcgctg tttttttaat gactcgcttg cttgtgcttg ttgtcgcttg
     1621 cgaagttcgc ttcgcgtaat aagcggtcct ttggccataa gccgatccct ctactttcct
     1681 ttggtcaata gttcccagta ttgaatcgca taaatcgtct ttgcatcaca aatcaactga
     1741 tctttcatcg cttgttgcgc ctcttcaaga gttagatgat acaactccag tacttcgtct
     1801 tcatcttgtg ctaaaggatt ctcgaccttc tctacccctt gtgcatgata aatatgaagg
     1861 acttcatttg caaaacctgg tgaaagatac atcgaagtaa gatggctcag cgacttcgca
     1921 cgatagccag tttcttcttc taattctcta gctgctgtca tttcgggatt ttgtccttct
     1981 cctggatcga tttttccagc tggaatctcc aaaatcactt tttctaaagg ttttcgaaat
     2041 tgtttgacaa gaagcagacg atcttgttcg tcaaaagcaa tgatcccgac accgccagga
     2101 tgaaatacca gttctctctt cgaagttcct ccatctggca aacgaacttc gtctacagca
     2161 acatcaataa tttttccgct atagatttct ttgcgactga ttgttttttc ttcaaattgc
     2221 tcattgttca gcatatcttc tcctgctttc tttgtaatca taactgcttt tttttcattt
     2281 ttcaattttt ctcaaaaact ccttattagt ttaccataga taaaccttag attttctcta
     2341 aatatagaaa atccttcttt agtccgatac tctttctagt agtccgtatg ctaaaataag
     2401 tatgtaatcg aataacgaaa agaattcaat actcaacgat aaatgacatg gagggtttat
     2461 tatgataaaa cgaaattggc cgtggcttct agcattggtc ttgctatttc tctttgtccg
     2521 aaacaatagt ttttcttttg ttctaggact tttattgata ggtgtagttt tagttttgtg
     2581 gggactcttt ggttcgcgca ggaaaaaggg aaaacaagaa gaaattcctg cactgactga
     2641 cgaacttgaa actcactatg aaaaaagcgg tatgacagcg aatgaaattt cattttttcg
     2701 acaaacaatg aatcaaacaa aaaatgagat caatcaattg caaatgaata tgcagcagac
     2761 agccaaactt aaagcaatcg atctccgcca tgatccagtc aaagcagcga aagctttatt
     2821 caaagaattg gtgaaagaac caaaccgact gcatgaagca agtcagtttc tttatacgca
     2881 tctgccgaat ctagttgatt tgacaaataa gtataatgag atcaatgacc atgagatcaa
     2941 aaacaaacag acctatgaaa aactagaaga aagcgcgcag atcatcgacc agctgtcagc
     3001 tttaatcgca caagattatc aaaaattcgt tgctgaggat ctagatgata tcgacgtaga
     3061 gatatctgtt gcgaaacaga gcttaaagcg tgataataaa tatgaaccag aacaaaagga
     3121 ttaactcttt tgttcataaa agaagactcg gaacattcag atgatgtctg gctgtttcga
     3181 gtactttttc taaagtagag acattcatgt aagaatcgag aacagattca acaaggagga
     3241 attttttatg gatcataaac cgactgaaac aaaagatgtt acaccagtta acgatacact
     3301 tgaagattta ttgaacaacc cgttttcaac tccaacagat acgctgacca cttcacaaca
     3361 agcggagatt gatcagctcc aagagcaaca gacagctgct cgtttaattg acaaactacc
     3421 ggcggaacgc caagaacaag ctaaacagct agcagcaaaa atcgatgcta atgatgcaca
     3481 gtctgtcatc agctacggat cggctgccca agcaaaatta agtgaattct cacaatcgat
     3541 gttgaatcat gtgcaagcac aagatattgg tcctgtagga gattccttaa ctgaactgat
     3601 gtatcgtctc caagaagcca atcctgacga actgcgtgcc ggagaaggga acatcttcca
     3661 gcgtgtcttc gggaaggtca aacaatcgat ctatgaagtg acagcaaaat atcaaaagat
     3721 tggtgcacaa attgacaaga tttcagtgaa attagataaa gaaaaagacg gtctgctaaa
     3781 agataatctg atgttagaac agctttacca gaaaaacaaa gactactttg atgcactgaa
     3841 tatttatatc gctgctggag aattgaaaat ggaagaactt caaacaacga tcattccaga
     3901 agcgatgaaa agagcagaag aaactggcga tcagatggat gttcagattg ccaatgatta
     3961 cacgcaattc ctagatcgtc tggataaacg tacgcatgat cttcgcttag ctagacagat
     4021 cacgatccag caagcaccac aaatccgttt gatccaaaac acaaatcagg ccttggctga
     4081 aaagatccaa gcatctatcg ctacagccat tccgctgtgg aaaaaccaag tcgtgatcgc
     4141 attgaccttg cttcgtcaaa aagatgcagt aactgctcaa cgccaagtct ctgaaacaac
     4201 aaacgactta ttgaagaaaa attcagaaat gctgaaaatc tcagccatcg aaacagcgaa
     4261 agaaaatgaa cgtggaatcg tggatatcga gacccttcaa accactcaaa atgatttgat
     4321 cgaaacaatc caagagacat tgcgtatcca aaaagaagga aaagaaaaac gtcgtcatgc
     4381 agaagtagag cttggacaca tggaagaaga tctgaaacaa aaactgttgg atttaaccca
     4441 atagatcacc tttcgcttgt tactaaaaca aacgcccaac aacagtttat tacaactgtt
     4501 gatgggcgtt tttcttatct ttcttctaac ttctccattg gagtctattt ctcattcatc
     4561 ttgctgtgtc catagccata gccaaaataa atgatcagtc caataaccat tacgataccg
     4621 aacacgatcc atgtcacagt ttgcagacga agcatcaata caatacaagt caaaatggag
     4681 acgattggca atagcggaac gaatggcact ttgaattctc cagcttttgg tttgccaaac
     4741 atttttctca acttcagtaa gcctagacta acaagcatca aataggcgag cgccatgata
     4801 ttcgttagtt ccgctaatac attcaatggg aaaaatccgg caaagaatac agctgccaca
     4861 ccagcggcat aagtcgcttt tttcggtgta cgatgctttt gatcgatttc tgtcataaac
     4921 ttaggaagta agccatcctt gctgacagca aacagtaaac gagcaagtga atacatcatc
     4981 gagatcgtta ccgtcagtag cgttaaaatt gcccctacag cgatcaccgc gcccactgtt
     5041 ccatgtccta catacctcat tgcaaaagcc actgggtcat tgactcctag ttcagtatac
     5101 ggaacgattc ctgtcaagat cagcgtcacg atgatgtaaa ggacagtagc aatcagtatc
     5161 gaaccaatga ttcctcttgg cacatctttt tgcgggtttt tgacttcctc ggctgccatt
     5221 gcaacggcat caaatcccaa gaaagcaaaa aacacaagag ctgcaccatc tagcacaccg
     5281 gaaaaaccaa aaggcatgaa tggctgccag ttatcaggtt taacgaaaaa tattcctaca
     5341 atgataaaca acgcgatgat accaaatttg acatatacca tggcattatt caaacgtaat
     5401 gctttcttgg cttcaagcga cacgatgtaa gtgacgaata tcactacgag caccgcaatc
     5461 aagtcaatgt atgtaccatt ttccggattg tacccgccag ttaatgcttg tggaagttcg
     5521 gcccctaaac ttttcaaaaa accttgcata tagccagacc atccggaagc aacagaggaa
     5581 accgctagta aaaattcccc gatcaacaac caccctgtca gccaggcagc aaattcacca
     5641 aatacaacat acagataggc atatggccca ccaatcactg gcactcgcga agcaaattct
     5701 gcgaaactta gtccagacaa aatgacaacg attgcagcta agacaaatga aagtgacagt
     5761 gctggaccag cattttgatt ggccgcaacc cctgtcacca caaatattcc cgtaccgatg
     5821 atcgcaccaa ttccaagcat gatcaaatca gacgttttta gttctttttt catctcactc
     5881 gtatgattga gattgatctc tttcttacga aacaaatcca ttgaagttcc tccccatttt
     5941 aggttggaaa acagcgatta aactgttttc atatacccta aaagggatac cacctaaaat
     6001 gactaaaagg caaccaacaa taacataaat gagctctttt ttcgtttttc tttcgccaag
     6061 gatgaaaatc ccacctaaag tagagataat gatccccatt tgtgaaagtg agaagccaac
     6121 agctaaacca agtgatttga ctgttagaag catgcagatg tttcctaagc cccataataa
     6181 tccacagatc atgtttttcc acacaaactg atcgacttta actttacgga aagcaaagaa
     6241 gcttgcgcct aagatcattc cgatactttg aggtaagata attgacatcg catccaaatt
     6301 cgcccagttg acgatgatgg tatatacacc ataaccaatc gtagagaaga tcaatgctct
     6361 aaaaccctta ccaaaatcaa gcattttatt atctgtatct atttttcctt cgtcatcttg
     6421 tcgggcagtc aaatacgcac cgcttacaag aagagctaaa gcaataatac cgtatacata
     6481 atctttcgtt tgtgtccatt catggaagaa aacggctccc gcaatcgtat tcaaaattaa
     6541 ttgaaaacca gtagacaatg gtagccctac agaaacaccc atgtacttca ttccatggaa
     6601 ctgtccattt tgtccaacac tccaagctaa gccggataaa aatccgatca agaaaatcca
     6661 aggggtgatt acaggactaa caacgaaaaa gacaactaaa gaaaacagaa atgcaccgat
     6721 cgtcattcct agtgtttgtt gattggcatc gccaccaatt ttaccactta ctaaaccaat
     6781 actaccccat gccaacatag ggactaatgc tattaaaatt tccataacca atctcctttt
     6841 atttcacatg ataagaaact tatcagcgaa aacgttaaca acacaagcac tttttttcgt
     6901 ttctaacgat tttctaacgt ttttcattat aaaaatttaa gattgggaaa aataaagtca
     6961 ttgttgtccc ttttccttca gttgattcag ccgtcaaatg gatacctaat ttttcggcca
     7021 gattttttgc taaataaagt cctaatcctg ttgaatgtgt tttgctaagt cgaccatttc
     7081 tcccagtaaa tcccttatca aagatccgtt tcaagtcttc cgctgggata ccgatccctg
     7141 aatctttaac tgaaaggctg actccttgcg cttccttttc tatgctcaca atgatgtttc
     7201 cgtgatccgg cgtatatttg atggcattac taagcaattg gttgaagata aaagcgatcc
     7261 atttagcatc ggtcaaaaca gtatgatcct caccaacgat ctcgtagcga atattttttt
     7321 ggataaaata atttgcctga ctgcgtatca caggctgaat gattcctttt agtccatatt
     7381 cttggatgag gtagtcccgc gagaaactgt cgagtcttgc ataatacaaa acttgttcta
     7441 cgtattcatc gatttttgat aattcatttt ctagtaatgt atacttttga tcgtcaatat
     7501 cgaactcgat cgaacgaact agcaatttag aagcggaaag tggcactttg atttcatgga
     7561 cccatgagtc aatataatct ttttggtctt gttgattact gattgctgat tgcattactt
     7621 cttggtgttc acggatcagc tgattgatat attcttctac cagtttttct tcttctgtcc
     7681 tcccaccact caaataattt tgcaaagggg aagttttttg tatgtcggct aattttcccc
     7741 accatcttct cttgctcaag taaccaccca gcagataaaa aatcagaaag acgccctcaa
     7801 tcaaagctaa ataagcaatt gtgctcaaat caactttgat gtttggcgcc agccacatca
     7861 caaagatcgt caatgcaata aaaaacagcc atcccaagat caatgtccac tgatctttca
     7921 aatatttaaa aaaattcatc ttaaccgctc atcctttcag ggaacgatat atccctgtcc
     7981 tacttttgtt tcgatatatc cttggatacc tgcctgttcg atttttcggc gtaaccgatt
     8041 gatgttgact gtcaatgtat tgtcatctac aaatcgttcg tcatcccaca gtgctcgcag
     8101 caatttttcc cgacttaaga tctttccatt gtgcttcatc aaaataaata atagacgata
     8161 ttcatttttg ctcaaatcaa tgatctctcc gttgatttcc atacttccgt tgtcaacatt
     8221 caacgtaatg ccattgtggc tcatcatttc actagataat tctgtgtagt tgtaagaacg
     8281 gcgaagtaat gcattgattt ttgcaatcag tacatcgatt tggaaatgtt ttgtcacaaa
     8341 atcatctgcc cccatgttca tagccatgat catatccata ttcgtattcc tgctggagat
     8401 aaaaatgatc ggtactttcg atacttcacg tattttttga caccaataat agccatccaa
     8461 aacgggaaga ttaatatcta gtaatacaag ctgtggttct tctctttcaa agtctgagaa
     8521 cacttgattg aaatcggtcg ttccaaaggt ttcaaattgc catttctcaa gttcctccat
     8581 gatcaattgt cgaatgatct cttcgtcttc gactaccatg atttttgcca taaaaaatcc
     8641 ctccatcttt cttcttgcta ctacaatatc aaagaagccc ttgtgaaaca agttggctta
     8701 cctggaaaat gtcattttag caaacgttaa aaaaaactgg aaatatgcga tttaatcgcg
     8761 tttgtctctt ccaagcagct taaatttatt atgttattct taataattgg tctattatct
     8821 gttatttttc tttcgttgtt tttgtctttt aaattttcga taacaccaat aaccgaaaag
     8881 cgttagcact agcaatatac ctagaaggag tataagtaat cgataaagat ggtatttttt
     8941 tgtctgttct atctttgaag agacttcttc tgtaaaggga actcgtcttc ctgtcactag
     9001 taatcggtga gtgttcacgg tgtaaggtgt acaagtgata agtgtgacta gatcctgctt
     9061 ttctctaatt gctaatgtat ttgtttttgt tggaaggaca acaattttct caacgacttc
     9121 ataagcgagc atccgaccat acacttcaag atagaatcgg tcatcttgct ccatttcttc
     9181 aagatccgta aagagttttt tctcagcaat accgctatgg gcggtaatca cggaatgtgt
     9241 actctctcct ccagttggaa aagaggtgcc ttgcaggact gtcgctcctc tatctaacaa
     9301 aagatcattc gtttcatcaa ataaaggcaa gctaacattg attttcggaa tatagatggc
     9361 tccgatcata tgttgttcgt aatattcttt tcctggattt tggacatttc taaccgcttg
     9421 ctcaaaagga tctttgactt gtcccattcc tgggattact gatgtatgag caagcgtctg
     9481 atttttcttt tcatgcactg ctaattgttg ctcatgtttt tcttctttat cgcgttcaag
     9541 ctgcttttga taattctcga tccttctttg atccaaataa ttgctgagag catctgctaa
     9601 aaatggatat gtaaaaactg cagctccggc aagaaacatc actgccataa ataattgtaa
     9661 taaaagactg atttgggttt gaggtctatt acctattttc tttttcattt tcttcacctt
     9721 cttatttaaa aaaactgcag caacctttat aaaaccgatt gctgcagctt atttttgttg
     9781 cttatacttc agacttcatt ttagatttac ggtaccagct gtacgctcca atcatcaaac
     9841 ttattccgat tagtaagaat gccaagagcc cgttcccacc agtagcagga agtgacccgc
     9901 gtttcatatt cggtactctt tctggccctg gattttctac tcctacgatc tgaatttctt
     9961 cattatagct tccataagag atgataaatt cagtaaaggc tgcctcacct gttggaagta
    10021 cataaccttc tggcgccatg gtctctttca tttgataggt tccataatct aacccttgaa
    10081 cctcaaagta tccatttcca tctgcgacaa attctgttgc ttgtccgctt gttgcccact
    10141 caattctatc tgctcctgat tcataaacag ctaaaggcga ctccccttta taaaatattg
    10201 cgtattcaga acggtcttca ttccacaatt cgaatcttgc atctttaagc aattcactgc
    10261 ttgatgcatc atatttttca aactttcttc cacctgttgt gactttctct ggcggctcta
    10321 ctccttcttc ataatcaaat tcatcatttc gtccgatttc aataaccgct gtgttgttat
    10381 ggaaatcatc cgcttctagt tctgtggaaa ccttcaaatt atacgtgatc gttaaatctc
    10441 ctccacgtgc atctgctaat ctacctaaag tatctacttt ggctactcca ttttcttctg
    10501 tcaaaatcgt cacgacaaac ccgttgctta ctacttctac tatataatct tgtccttttg
    10561 ttaaaatcgt ctcgccggct cgcacttcta tttcctgatc ataataagtt agaccaactg
    10621 taggcgtatc tgtgattttg taatttttga taacagcgct tccgttttca aggacagaat
    10681 cgatgaaata aggaataggt gctgtgatcg tgtaagaagc cgtttttcct ctttctagat
    10741 caatataaga aatcgtttct tgttctccag cttcattaat aatcgttact tgtctaaggt
    10801 cgctttcctc tacattcatc tgtttatctg cttctctgat ttcgtttttc ggatacaaat
    10861 gcacatctgt attgtatgtg tctttccatg tagaaccatc ccacacgcca tccaccatat
    10921 caggcatcat cactggcatc ataacaacca ttggagacgc gattctggaa atatgagctg
    10981 gcgaataagt ttctaagaaa agatagactt tatctctaga agaaggtgct tcttccgtca
    11041 cttggacggt agagaatacc gcttctccag cttcattcgt tgtttgtttg tcaatacttg
    11101 tcagtcgata ttttaaaaac caactttctg tgtgccgttt ttgaatccat tcaatcgctt
    11161 cggcagaatt aagaccgtct tctcgttccg gtgttaaagg attatctcga atcaaatcgt
    11221 aatatacttc cgttacgtca aacaaatcaa aatcgactcc tggaatattt tcttcaccaa
    11281 aatccgtaga aaccaatccg ctattcggtc gttcttccgg aacagatgag aaaccttttt
    11341 tgtgtaatgt aatcgtcact tcacttggtt tttgtgcgac ttcttcggct ttgactagtt
    11401 ttccgttccc gaaaatccct attcccgcag taacgagtaa cagtacactc attcccgtga
    11461 caatcatttt tttattcatt tttttctccc cgttcttttt ttattaataa aacagcacct
    11521 aacaataaaa gaattcctag taaagaaatc aacgttcttg cttcattcgt ttgcgggaat
    11581 acggaccatt ttcctgattg acctggattg cttggaccac tcggctcttt cggtttgtcc
    11641 gttgtttctt ttacggtctc gttataaaca cgtggtgttg cggattcata ggcagagact
    11701 ggaactttcc cggattctaa ttcagccatc tcctgtccgt taactactac atattgtggt
    11761 tggccttttg catccaccca aaattcaggg atgatgacct cgattctctt acttgcttca
    11821 tccatctcgt aaccttccac accttttaat tcttcaaaat aataggtgcc agaaggcaag
    11881 aaacgttgtc ctgtcgtaac aaggccctct ttatccgaaa tgaatttgct tacatttttg
    11941 tcattcaaag gatcattgtc tgctggtttg atccattgat ttttcaagtc attagcagga
    12001 gccatatcta aataatattt ccccccttct atcatctgat atagagcaaa aacagcacct
    12061 tctaatggtt ttcctttttc agttgttcct ctttgacgtc catacttgaa gaagtatgga
    12121 tctcttagat aaccgacatt tttaggatag atatgaatct cttgcagttc ctcggttgat
    12181 tctgtcgggt gataaattgg caaaatagca gcaattggga tagctgtctg atcgatatca
    12241 acatccaatc caacttctgg atcaatcgat tcttcgaaaa tcaaataaac tgcatcccga
    12301 tcttggtttt tcttaggtgc tttgatacgt gcaatcccgt ctcctaatcc gccaaccgta
    12361 tctttcccag ttgttaccga agtccctatt tggacaagcc tttcttctgt gattagctga
    12421 cggatattgt ttctgttcgt ttcagcgatt tgctggacga attctttagg agtcatgttt
    12481 tcagcagctt ttttttcatg ataataatcg gtcatgtcgt aaatggcaaa tgtcgctcca
    12541 tttagtggca ccgtctgtga aatgatatct gctgtttccc ctgcttcctc agagatagcc
    12601 aagccatcat tttcatggta ttcaaattga tcgttataat cgatatctcg aatcatccgt
    12661 ttatgcaaca cgaattccac gacatcttcc cctgattctt ctgccgacat cgcatgtgga
    12721 agaaggactg ctgcaagcgg tagtaaaaca agtaattgaa gcatcaaaca caacagcttt
    12781 ttcattacct tgctccctcc tttttagatt gtctgacaaa caaaccatag gctgctcctg
    12841 caagcgccat gaagaatgca gcaagcagga tatagaataa tcgtccggat cctcctgtag
    12901 caggcaacgg attttcagga tcgttcccga cactaagctg taatctgatt cgatttgtct
    12961 ccaaaagttc atattctaac tcttgctgta gatcaggcgt ctctgcttct tcgtttggat
    13021 aatacgaaat ctcaactttt agtgtacccg cttcttttcc tggaactacc cgatcatttt
    13081 ctatgtcagg ttcttctcga taactaattt ctaaaataaa gtaacctgga agttttctat
    13141 agctgtcagg tgacttcact tccttgatcc gatagacccc ttccaacaag tctgaagcat
    13201 tgaataggga agaatcgttt ggatctggtg ccaagcctcc ctcgatgatt tcatactctc
    13261 ctgcactatt ttgtttctca attgaaaatt ctgcgccttc aagacgtcgg ctattcatac
    13321 tgtcaatttt caaaagttcc aaatcgattg gcgctagttc atcttctaag gttacttgta
    13381 gtacaccatc gatgatttca tagccttccg gcaagggagc agtttcgtct tcgatgaccg
    13441 tatcttcaat gataaactta ccttcttcat tcagtgcaaa ctggaacact tgatcagata
    13501 gccgataccc atttggtgcg acagattccg agacctcata ttcaccaata gacagatgca
    13561 gaggttggtc gtaatttaaa tcgacatact tttctactcc tacggcacga gaatagaagt
    13621 atccgatccc aggcaaacgt ttcgattctt ctggttctaa cggattacca gtgtatgctc
    13681 gatacagcgg gaaggaagaa tcccccactt tcctgatatc gaaacctgca ccatctaatg
    13741 tatggccttc atggtctaat tttctaactc ggatctcccg ataatcaaac gtattgtaag
    13801 cagtgaatgc tacccataaa cgatcctctt catctgttgt atacgtgaga tattgccaat
    13861 tttcttcacc tgtttgcttg agttggatag tccctatagc attatcgtaa agtcgcaaga
    13921 tccatgtgtc attttcatca ggttctttga aaccttctgg gttctggctc tcaatgattt
    13981 tgtattctgc atagttggta gtttcttcac tatccttata aacaaatgaa tctggctctc
    14041 cgattggatg aataactttc tcaccatcca cgattacata tttcccgtct tcatctactg
    14101 aatagaacgt gagtctccct ttctcttcct ctacttcgtt cacaccagaa agccctttcg
    14161 ctactggata tccgatttcc agtccgttac catctgtttc ataaagttca aactctgcgc
    14221 cattgattgg catattactg ccttcaatta gtttattgat attcatgtgg attggcttga
    14281 attcatttcg catttccagt ttgacataca actcatcata ctctgtgcct tctatgttag
    14341 gctcttgtac aacagaaagc ttgtgatatt ctccttcata ataggaattc ggatctttac
    14401 cttccggtcc gccgactctc gaaccagatg tatattcatc tacaagctcg tagtgaccta
    14461 acatctcatc ttcgttggct gcatattttt tgatttggaa ttgatacgtc tcatctacta
    14521 actgataacg tggtggtcca gcgatctctc tgatccaaaa tatgtcgctg actgctccag
    14581 tttcatctcc taaaatcggc atcttcgttt caaagatcgc tattccgtcc gtggtagttt
    14641 tacttgtttc gattggttcg gcttccccac tctctggatt ttggtcatat aatgcaaatt
    14701 cgactccagc caacggctcg ccattttgac ccttcttgct gacttggaaa ttacggcctt
    14761 tatgttcgta acgaatggaa gaagatggga aatacatccg tccagtagtg atatcattct
    14821 cataatcctc caggttctga atataggcca tattgttcac tgtgcaaaaa tttccgtctt
    14881 gagctcccgc atcaagtttt acttggtact tgatcctgac catttcccct tcacctaaag
    14941 aaatcggaga aaatttataa gcttggtttt cccgtccgac atacgttgtc ggagtcgcca
    15001 ctacttctgg tggggcttgt ccatgacgtt cttcatccca tatttctggc tcttggtact
    15061 tcatgccgtt ttctcctgga tctagatggt aaaactgaat atctgccgat ctgccagctc
    15121 caaatggtga gacattaaaa ccagtttcat cataaagtgt ggcttgctgg atcgttctct
    15181 tgaaggtaga agagatatcc tccaaggctg taacaatgtc attcttgttg ttcgcattgt
    15241 aatatcgcgg tgttacgcca tcttcttcta aatcagcaat atttttcaat acatttcgtc
    15301 caatagcatc tagtcgttgt ctcccgctaa cgtttccatc gattcctaaa ccaatggaga
    15361 agatacttgg cgggttctct tgatacttgt ttttcagcca atgatgataa gcaactgtgt
    15421 tgatcgcaga tgacttttct tgcgaagtag gactgccatt cgtattgtta ttagaagaac
    15481 catcaccaac ccagtgagtc gctttattat ctccttcttt tacctctcca taacgatagt
    15541 gtacatttac ttcatcttct ggacggttaa agtcagatgc ataggtaact ggatgagtaa
    15601 accctgcatt agaagtattc ccagaaaact cctcaaaatt tctgaacaaa acgtcattat
    15661 cttcagcaat cttatcttcc atcacagtcc agttgctcaa actccattag tgctcgtacg
    15721 ataacttgac tgaatcggtg cataactgaa ggtcggtgtc ccatctccca caacgattag
    15781 gattttttct ggatttctat tttctccgcc attgtcttta tacaatgttt catagccatt
    15841 tttaagccct agtgtaagcg gagttcctcc gattggtgta cgatttaatg ctgtattctc
    15901 acttcccgtc aaacgattga tatcatttgt caatggaaag atgtccgaac tgatttgctc
    15961 atggttattg atagctgtac tattatggta aaaattcacc ataccgattc gaatatccag
    16021 actcgggtca gagagcagat ctttactcat ttcgtttact gcctcaatca acgcagcatt
    16081 tttagtttga ctattggtcc cagcggttaa ttcactcata ctcgctgact tatctagaac
    16141 aaaaacgata tcgattggac tgatttcctt tttctcgccc ccgatgacat ctagatagac
    16201 attgtaaagg gttgttgcat cttcaggatg tagatcagat gctgtgctgc ttggcagaac
    16261 aggttctacc cattttttga tgtacgcccc gttataatcc aagtaactgt tttcaaaatt
    16321 ccgttcattt ccccaaagct gaacggtttg agctggaacg tttctatctt cttcgcctgc
    16381 agttgatcca ttattagtag catagtcgta atttcgccag ttcgctcccc cgtttgtata
    16441 atcactatca tcgatcaagt tctctccgtc atatggcgag cctttgtctc cttgatagcg
    16501 ttcattgctt tgtgtccaat ttcctaacac ttttgtatag tcattcgttg taaacttcgg
    16561 gtagcgatgc tgttcgtttt caacttctcc gctaggatag atatattcat aggggtcttg
    16621 cgtagctgtt ggcccaagac gctccaaaat accgttgaat aactggcgtt gaatgcgctg
    16681 gagtgcttga ccgctgggta cgattggttc gtccagcttt tccatctcat tttcttcgct
    16741 acgttgaatt tcagcggaat cttctgtatc agtttcattt tcttgtaatt cttggttatc
    16801 tattctttca tcaaccacca cttgaagagg tagttaccct tcgttcacat cggggatctt
    16861 ttctgtttca aaaatcaatg tgccggtttc tgcttctttt gaataaactt ttccgacata
    16921 ccattcttga ccatcgatcg tctcgacttt taggtcttct ccatcttcat cataggagga
    16981 tagacctgtt ccacgaacgt tttttacggt accaatcccg gcggctgccg catcgattgc
    17041 taaacgtatt ctaccttcat tggcactttc ctttttttca aaagccagat gccattcaag
    17101 ggtttcttct ttttcaatat acttcccttc aatttttgca tagtcctcat ctaagaatac
    17161 ctcatcctcc tttgtttctg ttgactcagc agctacatcc agggtcgtca tatgatagac
    17221 tgactggaaa tatggtccaa atagcaaact gacagttact aactgcaaaa gcttcaattt
    17281 taaccctttc acatccttat actcctttca aaaatatttg tcttctttca caacaatcaa
    17341 caaaacaatg cccatctaat tataatttaa tttaatttta attttaaatc aaatgatatc
    17401 ctttttagtt aaaaaacacc aattatacaa catttattat taaa
//
LOCUS       DAFLWC010000062        17390 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.063, whole genome shotgun sequence.
ACCESSION   DAFLWC010000062 DAFLWC010000000
VERSION     DAFLWC010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17390
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.063"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            175..519
                     /locus_tag="L1V17_001947"
     CDS             175..519
                     /locus_tag="L1V17_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBN1236703.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            520..939
                     /locus_tag="L1V17_001948"
     CDS             520..939
                     /locus_tag="L1V17_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBN1236704.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVIFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1031..1381)
                     /locus_tag="L1V17_001949"
     CDS             complement(1031..1381)
                     /locus_tag="L1V17_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236705.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1347..2678)
                     /locus_tag="L1V17_001950"
     CDS             complement(1347..2678)
                     /locus_tag="L1V17_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HBN1236706.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2934..3500
                     /locus_tag="L1V17_001951"
     CDS             2934..3500
                     /locus_tag="L1V17_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBN1236707.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3645..3732
                     /locus_tag="L1V17_001952"
     tRNA            3645..3732
                     /locus_tag="L1V17_001952"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3677..3679,aa:Ser,seq:cga)
     gene            complement(3784..4989)
                     /locus_tag="L1V17_001953"
     CDS             complement(3784..4989)
                     /locus_tag="L1V17_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1236708.1"
                     /translation="MAKKEIDKRIKKHLTKKGEEKYQFSLYLGVDPLTGKKRKTTRRG
                     FSTPLAAERALKRLEADIQEKGLQASTAQKSKKFEYVYGLWFENYKKTVKESTWSSTK
                     QIFDTHILKVFGDKFIDKIDVFFCQEAVNTWSDSHPKIFKKIKNYTSNVFDYAASLQI
                     ITSNPMKLVSIPRGEALDIEDKNIEFYTKEELIKFLEAIRNDDDERYLFFSLLAFTGI
                     RKGEAFALTWSDIDFKSKTLNINKTVTRGYQGRLIVNTPKSKSGKRKIYLDNDLISLL
                     RKYYTKNKTIVTIQRENLIFHHDGLLYNPTVSRSWLNVIYKHHPELTKRITTHGFRHT
                     HASLLFESGASLKDVQERLGHADIQTTSNIYTHVTETQNKKVINNFVAFMKNSTQGES
                     KGESKNILG"
     gene            complement(5127..6015)
                     /locus_tag="L1V17_001954"
                     /pseudo
     CDS             complement(5127..6015)
                     /locus_tag="L1V17_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317363.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
     gene            complement(6102..6302)
                     /locus_tag="L1V17_001955"
     CDS             complement(6102..6302)
                     /locus_tag="L1V17_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236709.1"
                     /translation="MKIGMRKPSIKKSISARTTGKAKRKVKKAVIPGYGKKGSGWIKD
                     PKKAAYNKVYKKTTFSFWDLFK"
     gene            complement(6331..6753)
                     /locus_tag="L1V17_001956"
     CDS             complement(6331..6753)
                     /locus_tag="L1V17_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBN1236710.1"
                     /translation="MYLPQIDNKINKLVKLYQTRNPFRIARELKILVLEEDLGEIYGY
                     YSKFKQIKMIHINSSLDEMGKWITCSHELGHCVLHPNENTPMLSKKTLVSELKIEKEA
                     NYFATHLTIDPTLDGFDHMTKYEKLVCFGLPDEFDRFL"
     gene            complement(6770..7192)
                     /locus_tag="L1V17_001957"
     CDS             complement(6770..7192)
                     /locus_tag="L1V17_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1236711.1"
                     /translation="MTTFERIKELAKNKNKNLQQVAKDLKYGENYFYSLNAGKQPTAE
                     KLQEIADYFDVSVDYLLGRTEKKRYYDLTEKDERDIQKELQSLIDDLSNADGMAFSKK
                     DNEMSEATREALIISLENALRIAKIEAKKKYTPKKYRD"
     gene            7483..7674
                     /locus_tag="L1V17_001958"
     CDS             7483..7674
                     /locus_tag="L1V17_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236712.1"
                     /translation="MSNLDNGRAAIKEFMKENGITMDDLATAYGHTRVRMQQILDGHW
                     SGPKANRTILEIIRDYRIR"
     gene            7685..7951
                     /locus_tag="L1V17_001959"
     CDS             7685..7951
                     /locus_tag="L1V17_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236713.1"
                     /translation="MNILSEEFLTRLRIAIVEVVKDALSQLSKKNLSETRYLKKIEAR
                     KYVGGVNDQGFEKLIAHGLKEIRIDGFLRYDKKDIDELMAKYKI"
     gene            7963..8133
                     /locus_tag="L1V17_001960"
     CDS             7963..8133
                     /locus_tag="L1V17_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236714.1"
                     /translation="MGKFNRTLVFSAPLIIYALGLWGSRQALIGTIVYMLWIFIGLDE
                     AEYRAKKPVGRD"
     gene            complement(8192..8671)
                     /locus_tag="L1V17_001961"
     CDS             complement(8192..8671)
                     /locus_tag="L1V17_001961"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236715.1"
                     /translation="MSRKIDNIILLTTIFYLVIGATLSLLSFLSNSSLIVLNQKSILT
                     EFAHIDYFSFFKTGLICLFLSSFILYIGTTFCLMVLNLKMFIIEKWIVIIAKIFSSIS
                     IIIPMTLTFSKEQFNVATTFVSFIALFSFAVPKTFQSKSSNAKVNVENTDRKNDESY"
     gene            8716..9423
                     /locus_tag="L1V17_001962"
     CDS             8716..9423
                     /locus_tag="L1V17_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HBN1236716.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFDKKHRHVLTAIDELKEGVAEN
                     WADLFWEDTYVHPQNKQSYRIIYMNRDGFSLLAMGFTGKKALSFKLQYIEAFNKMEKE
                     LKDQLPSIPATKREMALLALAANEETNERVDAIESDLNDLKNNQLLAEPDYRTISNMV
                     RNKIRVICNQQHLNSKAKAELFKDLNGGIKRITGAVARNRIKAKQFDDVIDFINNWMP
                     STATMTIIKQMELLEDE"
     gene            9602..9943
                     /locus_tag="L1V17_001963"
     CDS             9602..9943
                     /locus_tag="L1V17_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236717.1"
                     /translation="MKKELSTLDQYLTDPSWGKSNIKETSNRKIRRNLLTDEELACDQ
                     DDLGNFVSIWDHVYLIHLSRKSKKTEYIYVIEDGLIDALEEYDRDNLIDISYYGSGKK
                     YIAEMEAEFDE"
     gene            9936..10682
                     /locus_tag="L1V17_001964"
     CDS             9936..10682
                     /locus_tag="L1V17_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HBN1236718.1"
                     /translation="MSEKEQPLKNRSDNTLFNTLYKINVKDVTEKRNNLTYLSWAWAW
                     AEVSKVCEAVDYEIYHDPETYLPYVFDKKTGYMVFTSITVNGVKRDMWLPVMDGANKA
                     MKDEPYTYEVNDYQWNNETKKKEIVGKIEKRVEAATMFDINKTIMRCLVKNLAMFGLG
                     LYIFAGEDMPEDVSMLEPATQRSKKLFLDALQLVANKYEKSIDEAIVALTDAASITAD
                     DSKWTKRDLGILKRGVNWIEDQYREETKEK"
     gene            10688..11374
                     /locus_tag="L1V17_001965"
     CDS             10688..11374
                     /locus_tag="L1V17_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236719.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDIGATINEEVNIDRLKTMYDGYDGD
                     RIIEVRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHNIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            11381..12214
                     /locus_tag="L1V17_001966"
     CDS             11381..12214
                     /locus_tag="L1V17_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HBN1236720.1"
                     /translation="MSDNKRYYYLKLKENFFDSDEMVLLESMPDGYIYSNILLKLYLR
                     SLKHEGKLMFNDRIPFNSTMLATITRHSVGVVEKAVQIFRDLQLIDVLDNGAIYMSDI
                     QSFIGKSSTEADRKREYRKKIEEAKRNLITGGQVSDKCPDKTTPELEIEIEKDIDIDK
                     EEKKGKYSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEY
                     VINWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKNNHKKQSQKLQYSNPSEYDDLP
                     I"
     gene            12231..13082
                     /locus_tag="L1V17_001967"
     CDS             12231..13082
                     /locus_tag="L1V17_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBN1236721.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALERAKSFVNDVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNAELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            13079..13438
                     /locus_tag="L1V17_001968"
     CDS             13079..13438
                     /locus_tag="L1V17_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HBN1236722.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            13453..13614
                     /locus_tag="L1V17_001969"
     CDS             13453..13614
                     /locus_tag="L1V17_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBN1236723.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERIKAVMVNETARKAINLHIVNL
                     RREIRRLEE"
     gene            13617..13916
                     /locus_tag="L1V17_001970"
     CDS             13617..13916
                     /locus_tag="L1V17_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236724.1"
                     /translation="MGKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWTEKPKRK
                     TPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            13916..14230
                     /locus_tag="L1V17_001971"
     CDS             13916..14230
                     /locus_tag="L1V17_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HBN1236725.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKAKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYREILNEYFE
                     ED"
     gene            14407..14718
                     /locus_tag="L1V17_001972"
     CDS             14407..14718
                     /locus_tag="L1V17_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBN1236726.1"
                     /translation="MDELITKVEQWAKDKGLDQADSSKQMLKTIEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLNQAYNEIKGRTGKMVDGVFVKSSDLEDS
                     K"
     gene            14715..14933
                     /locus_tag="L1V17_001973"
     CDS             14715..14933
                     /locus_tag="L1V17_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr domain protein"
                     /protein_id="HBN1236727.1"
                     /translation="MISLTIFWCVIGGLLAMLGAYLIYESAKGKKYTAVGIILFVVGI
                     LVAIGAEINLYLNGTTEELMWFLLWTRR"
     gene            14946..15227
                     /locus_tag="L1V17_001974"
     CDS             14946..15227
                     /locus_tag="L1V17_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236728.1"
                     /translation="MGDMGEYWKDIKPHLKERRKQHVRKMGNSATKNIETLGFEFTHY
                     PNNHQFAINTHNGIIDYWGTTGTWIERKTKKRGKGIRSLRKYINQEDSK"
     gene            15224..15550
                     /locus_tag="L1V17_001975"
     CDS             15224..15550
                     /locus_tag="L1V17_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236729.1"
                     /translation="MNYTQQELTDLCPKHVAEFINNEVLPKYADGLNTAENVTDFMIN
                     DAIDRLIFLEIDCIAYYRLHAEVALIDPYIALSQNRKILVAYIDTKQILEGRDVEIEI
                     DEEEVG"
     gene            15547..15744
                     /locus_tag="L1V17_001976"
     CDS             15547..15744
                     /locus_tag="L1V17_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236730.1"
                     /translation="MKAYTIKFYGNKTYVYILSGLRLDFRGYSKEDLLESLYGYGYLN
                     EDELISLEKFTNAWTIEEEAE"
     gene            15741..15950
                     /locus_tag="L1V17_001977"
     CDS             15741..15950
                     /locus_tag="L1V17_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236731.1"
                     /translation="MKIYVVKFGNKFYRSDERSIGANTLFIVDILQSARWFDSLEEAN
                     QVSRRLGGLTQVYELVTVDHEEVER"
     gene            15947..16234
                     /locus_tag="L1V17_001978"
     CDS             15947..16234
                     /locus_tag="L1V17_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012197617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236732.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKKRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVARLVDMKAI"
     gene            16826..17293
                     /locus_tag="L1V17_001979"
     CDS             16826..17293
                     /locus_tag="L1V17_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HBN1236733.1"
                     /translation="MVLFDVKKYETPEAKDVDMDRTKHNVGVFLSAYLSARCRIGQPR
                     EPKVTASYSLVPPSTANNTFEAERMMIEREEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
BASE COUNT         6116 a         2774 c         3403 g         5097 t
ORIGIN      
        1 aaaataaaaa aagcgttagc aactatgctt aaaaagcata tcgactgaat aaactaagca
       61 ttggacaggc tgaaagacta catttaaaat gaaatgcgaa gaaacaatag aaaataaagt
      121 tgccttagaa ccatagttga atcacctaac agtcgtgaag ggagaataag agaaatggca
      181 gaaaaacaaa ccgcaggacg agatcaatta ggagattttg caccaaaatt tgcagaattg
      241 aatgatgatg ttttatttgg acaagtatgg tccagagaag aattatctgc tcatcagcgt
      301 agtatcatca ccatatctgc attaatttca ggaggaaatt ttgaacaatt gccagctcat
      361 ctgaagattg gcaagcaaaa tggcattact agtgaagaaa tagcagaaat cattacccat
      421 ttagcttttt atgtaggatg gccaaaagct tggtcagctt ttagtttagc aaaagaaatc
      481 tatttagaag aaaatagcga agataagaaa gaggcgtaaa tgacgacaaa acacgaagaa
      541 atacacaatg gcgtgatttt tccagcaggt gaaaaaaacg aagcttacgc tcaagtattt
      601 accgggcaaa gctatctgaa tatgttagtg aatgatcccg aagtttctgt tggtgtaggt
      661 aatgtaattt ttgaaccagg ttgtcgcaat cactggcatg tccataaaga cggctatcaa
      721 atcttacttg tgaccggagg agaaggctgg tatcaggaag aaggaaagcc agcaagacga
      781 ttaatggctg gagatgtcgt cgtaacgcac aaagggatta aacattggca tggtgcgaca
      841 aaagacagtt ggtttgaaca tttggcgatc actgctggta attcagagtt tttagaacct
      901 gtaacagatg aagtgtatga aggattggaa aatcaataat gtcaagcttg aacagctcct
      961 gaaagtagat tttaatcgaa ctttcaggag ctgctttttt gattcagtct tttataaata
     1021 gaaaataggg ttaataatag gaatgagaag cacgtcgaaa gatcttaata ttgataatcg
     1081 gctgggcata catgatttcc acgtcatcaa tcaaactacc taacagatga taatcttccc
     1141 gatcatgtcg gggattacct aatagttctt gatagtagat ttccatacta gggtcccgag
     1201 gattgttcag caaatcagca agtacatcta aatcttctgg ctgagtttct gccgtaccct
     1261 gtatctctat gaaaagccct tcctcagcaa attctactcc aatacgtatt tcagttattt
     1321 catgggaata taaataagta agaagctcat cgatgattct ttttgataat tctttttcca
     1381 agtgtctttt tttcctttct gacagcggta aagttatcta gtatcggtac aaggatacct
     1441 gcaacgaaac cagttgaaaa accactgtta tatagattta gtcctccgtg caaagtgctg
     1501 acgttatgga caagagcaat atgtagtaca ccagctatta caccgtaaaa actgccgtaa
     1561 aaaccgctta tgggcgcgag acctgtccca aacacagctg caacaagcat gccagtactg
     1621 gtgatctcat gaaaagttcc aaacaaagaa gcaataaata ttccgactag tatcggaaaa
     1681 ctgtttttta aatgacaacc aaaagcactg aaacccaccg cagataaaat agcaccgatg
     1741 acaggtccat ttaactgacc gccaaccagc aaaacataag aagacagcat cagaccaact
     1801 aagcctatgt tgatcaaagt agcaccaata ccagaattag caatgaaatc agttgtcaat
     1861 tttccagatg aatcgaaaat ttctcgaatc cccaaaagcc gaaaggaatt ataatagaaa
     1921 ccaattccga ctgtcagcga aaaaaagcca aaaataatcc aaatgagagg aaagtgatat
     1981 tcattgaaaa ccaatgtatt ttcgacgatt gaatagctga ataacctcaa aacagcagta
     2041 aaagtcatcg caatcaaccc agaggtgaat ccaatattat aaagtgtgaa tccacgatgg
     2101 aaaactaaag tttgagcagc taagggcgga agaagtagac caattgctat gccagctaaa
     2161 ttccccaata aaatacctat cagtaaagga aaacgcatac caaaagtgat ataactaacg
     2221 accggtgata atgcgctacc aaacagtccg atcatgatgt actgagaaaa aggtttattg
     2281 acaaatacag cgtatagata cacacctaaa atgattgaga tagaattata aaggtttttg
     2341 ccaaaaaaag agaaaccggt aactgttaga atcgaagcaa ataagggacc gtttaaaatc
     2401 accttgtgcc gataagctaa aagcacagaa agtaaggtca aaatccctac atttatgaat
     2461 gcgcttccga aaccgcctaa agcaaaataa tctgtcaaaa gattgcttgg cgaggtaaga
     2521 atagttagca atccactcca attatcagta ggagtattag aaagcaagcc aataaaaaga
     2581 aaaaaaacac ctgtaaaacc aagataaaaa tactttcttt tctgtgaaac gattcgtttt
     2641 tgaggatgaa tataaataac gtcagtttcg ttttccatta cacaccttct ttttcatttt
     2701 ctttaactat aacttgaaat gaaagatttg gacaactatc atttaggtca aaactaaaaa
     2761 tgtaagggaa cccattgaat ttaaccaaat ttttttaatt ttgcaaaaaa aagttaaaga
     2821 agactgaaaa aaaatttaaa atataacgtt ttgagtaaaa tgtttgcaaa aaatgctaaa
     2881 aatagggtac aataaaacaa catatactgc agtaaagaag tgggggagtt ttaatgagaa
     2941 gaaaagtcta taccaaggat caaattctaa aagctgctta tgatgttgtt gcaaaggaag
     3001 ggtttaaagg atttactgcg agaaatattg ctaaaaagat ggggatttcg acacagccga
     3061 tttatctgga attcaaaaac atggaagatt taaaaaatac gttgctggat tctatctttg
     3121 aacaactaaa agaagatgtt ttccctattg aacgtactgg tgataaaatc attgatctcg
     3181 gtttgaacta tatctacttt gcaaaaaagc atcatagtct ttacatggca ttgtacattg
     3241 atgaacatgg ggacggaaag aaaatgcatg atttttcata caattatttc cgtgaaatag
     3301 ttaaagaaga tgaaagatac aatcaattat cggatgaata tgtcgatgct ctgcatactg
     3361 gtacatgggt agcagtgact ggcttagcgt cattgatgtc atcaaacatc atgcatccaa
     3421 cagaagaaca aatcattgca ctgatcaaac ggacaattga ctcgatttta gcattagata
     3481 atcctgaaat aatcagatag tgttctatca gtatgaattt gatcggtaag tccgttggct
     3541 gcaaactgtc aatggacttt tttgctaaaa aaagcgattt ctgttattta tctattagaa
     3601 ataggcttga catttcgtga aaaaagttta aaaatagtac ttacggaagg ttggcagagt
     3661 ggtaatgcac cggactcgaa atccggcgaa ccggctaata ccggcgcgca ggttcaaatc
     3721 ctgtaccttc cttatatatc aacgattaga cacgatttcg atcgtgtctt ttttgttgta
     3781 tatttagcct aaaatgtttt ttgactcccc ttttgactcc ccctgagtac tgttcttcat
     3841 aaatgctaca aaattattga tgactttttt gttttgagtt tcagttacat gagtgtaaat
     3901 atttgaagta gtttgaatgt ctgcatgccc taaacgttcc tgaacatctt ttaaagaagc
     3961 tcctgattca aaaaggagag aggcatgagt atgtcgaaaa ccatgagtag tgattctttt
     4021 agtcaattct ggatgatgct tatatatgac attaagccac gaacgtgaaa ctgtagggtt
     4081 atagagaaga ccatcatggt gaaaaattaa gttttccctt tggattgtaa cgatcgtttt
     4141 gttttttgta taatactttc tcaataaact gatcaaatca ttgtccagat aaatttttct
     4201 ttttccagat tttgatttag gagtatttac gatcaatctt ccttgataac ctcttgttac
     4261 agttttattg atattgagtg ttttgctctt aaagtcaata tccgaccagg tcagagcaaa
     4321 agcttctcct tttcttatac ctgtaaaagc caatagggaa aagaataaat atctttcatc
     4381 atcatcgttt cttattgctt ctaaaaattt gattaattct tctttagtat aaaattcgat
     4441 atttttatct tcgatatcta gagcttctcc acgtggaata gaaactaatt tcataggatt
     4501 gctagttata atttgtaaag aagcagcgta atcaaaaaca ttagatgtgt aattttttat
     4561 tttcttaaaa attttaggat ggctatcgga ccaagtgttt actgcttctt gacagaaaaa
     4621 aacgtctatt ttgtcaatga acttatctcc aaacactttt aagatgtgtg tgtcaaaaat
     4681 ttgtttggtg gaggaccaag tgctttcttt aactgtcttt ttataatttt caaaccataa
     4741 gccgtaaaca tattcgaatt tcttgctctt ttgagctgta gaagcttgca gtcctttttc
     4801 ctgtatatct gcctccaatc tttttaaagc tctctcagcg gctaatggcg tactaaaacc
     4861 tcgtctcgtt gtttttcttt tttttcctgt tagaggatca actcctaagt acagactaaa
     4921 ctgatatttt tcttcgcctt tttttgttaa gtgcttttta attcgtttat caatttcttt
     4981 ttttgccatc tttatctttc ctttcgtacg tttgttcggt tgtacagcgg atttcgagat
     5041 ggtaaaatag ggtacaacaa atagacctac tttaccgtag ctctttgcac atttgcgttc
     5101 ttggtcgggc ggcaaatgtg ctttttttat ttcactctta gttcttgtcc tggataaagc
     5161 atgtagttgt ttggatccat accgtttaat gcaaacagtt gatctaccgt aattccagct
     5221 cgttcagcta tttgtttggt cccttcacca ggttgcaaag tcaaggtttc ggtttcagat
     5281 gaagaaggtg ccgttggttg agcttgatta gctggtacat aatcttgtgg tactgattgc
     5341 tccgttgaac tgggagtggg tgaaacttgt tcaacacttg aactaggagt agcttctgca
     5401 tagttttcta cactttcagc agagtaagta ctactagttt caggaggcgt attctgcgca
     5461 atagcagctt gttctacagt actagaagat gcaatagtac tttctgttgt agtcgaagat
     5521 gattgttcgt tgctacttgt tgagctagta gttgttctag attctttagt ttttttcctt
     5581 tttgtagggt ttcaaaacta atttctcatt atcatcagat ttgttaggct tttctggagt
     5641 taaaataata tttttatctt ctttgctgac agtatatttg gcatcattat ctttgtcttt
     5701 atcatctttc caagtcataa catcgccttc aagtgtatac tcaaatttgt aattcatttg
     5761 gtcgactaag cttttagcaa attcttctcc catagcctcc caatcgttac ttgaagttga
     5821 tttcatagaa cttgtgtcaa cactaaaaga tacgacgtga tcagaaaatg atacgatcat
     5881 attaggttcg tcatctttgg ttgcttcaat caaccaatca ttagctttta aatcttctgt
     5941 agttactttt ttaccacaag cagtgaaaag taacagagaa gcaaaaacta ataaacttgt
     6001 tattactttt ttcatttttt attcctcatt tctatgatat gatttttatt ggggaatctt
     6061 agaaataagg tttcgagtcc gtgttgctgc acgggctttt tttatttaaa taaatcccaa
     6121 aaactgaatg tagttttctt gtatacttta ttgtaagcag ccttttttgg gtctttaatc
     6181 cagccgctac cttttttccc ataaccagga ataactgctt tttttacttt tctttttgct
     6241 tttccagtgg ttctagcgct tatggatttt tttatacttg gttttctcat tcctattttc
     6301 atctatatcc tccttacgtt gtattataat tcacaagaaa cgatcgaatt catctggtaa
     6361 tccaaagcag acgagctttt catattttgt catatgatca aagccgtcta aagttggatc
     6421 aatagtcaga tgagttgcga aataatttgc ttctttttca atttttaatt cagatactag
     6481 cgttttttta gacaacatag gtgtgttttc attcggatgc aaaacacagt ggcctaattc
     6541 atgactacaa gttatccatt ttcccatctc atctaaacta gaatttatgt ggatcatttt
     6601 tatctgtttg aatttactat agtaaccata aatttctccc aaatcttctt ctaaaactag
     6661 tatcttcaat tctcgtgcaa ttctaaaagg attgcgtgtt tgatatagtt ttaccagctt
     6721 attaattttg ttatcaattt gaggtaaata cataaacaac gtactccttt taatcgcgat
     6781 attttttagg tgtgtatttt ttcttagctt ctattttagc tattcgcaaa gcattctcta
     6841 aagaaataat gagagcttca cgtgtcgctt cactcatttc attatctttc ttcgaaaaag
     6901 ccattccatc agcattagat aaatcgtcga ttaatgactg caattctttt tggatatcac
     6961 gctcgtcttt ttctgttaaa tcatagtatc tttttttctc agtacgtcct agcaaataat
     7021 ctacagatac gtcgaagtag tcagcaattt cttgtaactt ttcggcagtt ggctgttttc
     7081 ctgcgtttaa actataaaag taattctctc cgtacttcaa atctttagcg acttgttgaa
     7141 ggtttttatt cttgtttttc gctagttctt ttattctttc aaatgttgtc attccaacgt
     7201 tcctttccaa cacgaaaaaa taatttacga aaaagagtaa aaatagcttt acaattttac
     7261 gatatagagt tattatttat ccgtaagtta atttgataga aaaaagcaaa ctaaaaacac
     7321 accttatagc ataaagtttg gcgaccaagt gcaaataaaa ggttttgtta taggcttatt
     7381 tctctatgta ttcattttac tctatagtgt aaaaatgtca atggaaatta tattttttct
     7441 atcattttaa cttacaaatt tataaaaaaa ggaagtgggt taatgtcaaa cttggataac
     7501 ggtcgtgcgg cgatcaaaga gtttatgaaa gagaatggaa taactatgga tgatttggct
     7561 actgcttatg gtcacacgcg tgtacgaatg caacaaattc ttgatggaca ctggagtgga
     7621 ccaaaggcaa acagaactat tctagagatc atccgtgatt acagaattcg ataggaggca
     7681 agtcatgaat attctaagcg aagagttttt gactcgttta agaattgcaa ttgttgaagt
     7741 tgtaaaggac gcacttagtc aactttcaaa aaagaatttg tcagaaacac gatatttaaa
     7801 aaagatcgaa gctagaaaat atgtgggagg tgtaaacgat caaggttttg agaagttaat
     7861 agctcacggt ttaaaagaaa ttcgtataga tggcttttta agatatgaca aaaaggacat
     7921 cgatgaactg atggctaaat acaaaattta aaggaggtca acatgggaaa gtttaatcga
     7981 acattagtat tcagcgcgcc actaattatc tacgctttag gtctatgggg tagtagacaa
     8041 gcattaatcg gcacgatcgt ttacatgctt tggattttca ttgggcttga tgaagctgag
     8101 tacagagcga aaaagccagt cgggagggac tgactaaaaa agtctaatgt ctataagaaa
     8161 ggtttgacaa taaatgaaag aattattttt tttaataact ttcatcattt tttctatcag
     8221 tgttttctac attaaccttt gcgttgctag atttgctttg aaaagtttta ggaacagcaa
     8281 acgaaaatag agctataaaa gatacgaatg tagtagctac gttaaattgc tctttagaaa
     8341 acgtcaatgt cattggaatg ataattgata tcgatgagaa aatctttgcg ataataacta
     8401 tccatttttc aattataaac atttttaaat taagcaccat tagacaaaat gtagttccta
     8461 tatagaggat aaatgaagat agaaataaac atattagtcc agttttaaaa aaagagaagt
     8521 aatctatgtg ggcaaattct gttaatatgc ttttttgatt taacacaatc aaactactgt
     8581 tggacaaaaa tgacagtaag gaaagagttg ctccgattac taaataaaaa atagttgtta
     8641 acaatattat attatcaatt tttctgctca tgttttcacc ccaccagaat tatatcaaaa
     8701 aggagagaag aaataatgca agaattagta attttgaaaa ataaagaagc tgtgactacg
     8761 agcttacaag ttgcagaaag cttcgataaa aagcacagac atgttttgac ggctattgat
     8821 gaactaaaag agggggttgc cgaaaattgg gcagacctat tttgggaaga tacttatgtt
     8881 catcctcaaa ataaacaatc ataccgaatt atttatatga atagagacgg cttctctcta
     8941 ttagcaatgg gcttcactgg taagaaagct ttaagtttta aacttcaata tattgaggcc
     9001 ttcaacaaga tggaaaaaga attaaaagac caattgccat caattccagc aactaaacga
     9061 gaaatggcat tacttgctct agctgcaaac gaagaaacga atgaaagagt agacgctatc
     9121 gagtctgatt taaacgattt gaagaacaat caacttctag ctgaaccaga ttaccgaaca
     9181 atttctaata tggttcgcaa caaaattaga gttatttgta atcagcagca tttaaatagc
     9241 aaagcaaaag cagaattgtt taaagacttg aatggcggaa ttaagcgaat cactggagca
     9301 gtagctagaa atcgtatcaa ggcaaaacag ttcgatgatg ttatcgattt tattaacaat
     9361 tggatgcctt ctacagcgac gatgacaatt attaagcaaa tggagttgtt agaggatgaa
     9421 tagagctgaa gcgctaaaaa taggcgtaat aattgctaat cgctggtgga gacacaataa
     9481 accaaacatc ctaagccaac aacatattga taagcaaaaa gcatggcaac aaataaaaaa
     9541 gtgactcagc cgaccaaagc aatgagtcac aaagaaaata catctaagga gatgttacca
     9601 catgaaaaaa gaactttcca ctctagatca atatttgact gatcctagtt ggggcaaatc
     9661 gaatatcaag gaaacaagca atcgaaaaat cagacgtaat cttttgacgg atgaagaact
     9721 agcatgtgat caagacgatt tgggaaattt tgtgagtatt tgggatcatg tctatcttat
     9781 ccatttatcg aggaagtcca aaaaaactga atatatctat gtcatcgaag atggcttgat
     9841 tgatgcgcta gaagagtatg acagagataa cttgattgat atctcttatt acggatcagg
     9901 taagaaatac attgctgaaa tggaggcaga atttgatgag tgaaaaggaa caacctttga
     9961 aaaatagaag tgataatacg ctttttaata ccttatacaa aataaatgtg aaagatgtta
    10021 ctgaaaaacg aaataacctc acttatcttt cgtgggcatg ggcttgggca gaagttagca
    10081 aagtgtgtga ggcagtagat tatgaaatct atcatgatcc agaaacatat ctgccgtatg
    10141 tctttgataa gaaaacaggc tatatggttt ttaccagtat cacagtcaac ggagtaaagc
    10201 gtgacatgtg gttaccagtc atggatggtg caaacaaggc aatgaaagat gagccatata
    10261 cctacgaagt caatgattat cagtggaata acgaaacgaa gaaaaaagag attgttggaa
    10321 aaatcgaaaa gcgagttgaa gcagcaacta tgtttgatat caacaaaacg atcatgcgct
    10381 gtcttgtaaa aaatctagca atgtttgggc tagggctata tatatttgct ggcgaagata
    10441 tgccagaaga tgtctcgatg cttgaaccag ctactcaaag aagcaaaaag ctattcttgg
    10501 atgctttaca actggttgct aacaagtacg aaaaatcaat tgatgaagca attgttgcat
    10561 tgactgatgc ggcttctata accgctgatg acagtaaatg gaccaagaga gacttgggca
    10621 ttctaaaacg aggcgttaac tggattgaag atcagtacag agaagaaaca aaagagaagt
    10681 gatatgagtg tttaaaccat tgatcgattc atattcagcg gttctgaaaa agttcaaagg
    10741 aaaagacata ggtgcaacga tcaatgaaga agtgaacatt gatcgactaa agacgatgta
    10801 tgacggatat gatggcgatc ggattattga agttcgattt attgatccac gtcgatttac
    10861 tgtgcagcaa cgaaacttca tctatgcgct gataggcgat attttcatcg atacaggcat
    10921 gccaacggac ttctggaagg aattctttta cttccgtttt gaaggcgtca cagggcgcaa
    10981 aataagcctc aaagacgaat cgaatacaac tgtgagtgat gctaatgtct tagcaaatat
    11041 catcttagat ttcatctttg aacatcatat tcctttcaaa gaaggctatg agattttacc
    11101 agcgaatcaa gaatattact tctacaaatg catcacaaaa agagtctgct gcatctgtgg
    11161 caaaacagga gctgacatcg atcactttga caaagcgcta ggaagacgaa agcgcaaaga
    11221 agttgatcat tcagagtaca catttgcagc actctgcagg attcatcaca cggagaaaca
    11281 caatataggt gtgatcaatt tcaaaaataa atatcaaatc aaagggatca agttaaacca
    11341 ggaaacaatt aagaaactta gaataggagg gtaaaaaata ttgtctgaca acaaacgcta
    11401 ctactattta aaactaaaag agaatttttt cgatagtgac gagatggttc tcttagaaag
    11461 tatgccagat ggctatattt attctaatat tcttctcaaa ctttatttaa gaagtctaaa
    11521 acacgaaggt aagttgatgt ttaatgacag gattccattt aactctacaa tgctcgcaac
    11581 tattacaaga cattctgtag gagtcgtaga aaaagcggta caaattttcc gtgatttgca
    11641 gcttattgac gtattagata acggagcaat ttatatgtct gatatacaaa gtttcattgg
    11701 aaaatcctca actgaagcag atagaaaaag agaatacaga aagaaaatag aagaggcaaa
    11761 acggaattta ataactggag gacaagtgtc ggacaaatgt ccagacaaaa ctacaccaga
    11821 gttagagata gagatagaga aagatataga tatagataaa gaagaaaaga aaggtaagta
    11881 ttctgacgaa cacttacgcc ttgctaaaaa attgcaaagt aatttaactg aagattttcc
    11941 aaaagaaatg aacaaagtag atatcgaaaa atgggcagac acaatcaggt tgatggaaga
    12001 aagagataaa gcgtctatag aagcgattga gtatgtgatc aattggctac ctacaaatga
    12061 attttggttt ggaaatatta gaagtgctaa gaaattgaga gaaaaatttg agaagctcaa
    12121 attcgaaatc aaagcagaca agaataatca taaaaagcaa agtcaaaaac tacagtacag
    12181 caatcctagt gaatatgacg acttgccaat ttaaaaagga gatgcatcac atggaaagcc
    12241 tagcaaatgc tatggagaaa ctaataagaa gagtattagt gcaaagcggg aaatgtccag
    12301 aatgtagcga acctttgtat agttggcgag ctaaaaataa ggatggttca gaacgttgta
    12361 aaccaacatg catgagttgt ggttataaag cgttacgtgt gaaagaggat atacagaccg
    12421 aacggatata taacgacagc ttaaaagcac gagcgttgag tttttttcaa aatggttcgg
    12481 tattaacaga taaaactttg tttaaatgca aaatggagaa ttatcacgta gtggaccaag
    12541 aaacgaaaat tgctttagaa agagctaaaa gctttgtaaa tgatgtctta ctgaaccatc
    12601 ctgcacattt cattctatca gggaaatcag gaagcggaaa aagccacttg tcaatggcga
    12661 cagcttggga aatacttgag cgctcaaatt atgacaagaa aatacttttt ataagctatc
    12721 aagagttatt agagcaaata aagttttctt ataacaatgc tgaactgaga aaagaaattg
    12781 aaggatcgct tatagccgat atcaaaacaa ctgatttggt ggtttttgac gatattggag
    12841 ctgaattagg tagcggggta tcaaatagta ggcagtttac aaacaacacg ttaaacacgc
    12901 tcttagaagc cagacagaac aaggcaacga tcatcacaac aaacttatcc ggtcctgaac
    12961 taagagaagc ctacggcgaa agaattgttt ctagaatatt taagaattca gaaggttatg
    13021 cgctgaaatt ccaacaaaca gcagacaagc gcataaaacc agtgaaaggt agtatcgcat
    13081 gaataaatac cgtaataaga aaactgttca tcgaggtatc aagtttgatt ctatcgcgga
    13141 agcagagtat tacgatttag ccttgtggca agcagaagcg aacggctgga aagtaaaact
    13201 tcaggaaaga tttgagctga tgccgaaatt tgaactagat ggaaaaaagt atcgcaagat
    13261 cgagtatatt cccgacttca cattttataa aaacggcaaa cttgtcaaag tcgtagatgt
    13321 caaaggaatg cagacaaaag actttaagat caaggcaaag ttgttctgtc atcaatatca
    13381 agtgccgttg atattagcta aaaaatatcg gaatacgttc aaggaagagc gtttttaacg
    13441 aggtggtcca tcatgacaac agaagaagtg attcaaatgc gtattcgaag ccttcaacgt
    13501 gagattgacg atctggaacg gataaaggca gtgatggtca atgaaacggc gagaaaggca
    13561 atcaatttgc acatagtgaa tttaagaagg gaaattcgta gattggagga atgagcgtgg
    13621 gtaagaaagc agcaatgaaa cgaatcattg aactgacaca ttctgagaat tggcaagaag
    13681 acaaagaaat agttgcagaa gtccaaaagc tcggtaaatc aatgtggact gaaaagccta
    13741 aacggaaaac gccgagaaaa attgcaatct ggcatggtga tcgaattcta gtaacgggta
    13801 cagctgaaca gttatctgaa attactggac tgagcaaaaa catcatctgg gatagagcta
    13861 ggagcttatg gattgattca aaggggcgac agtttaggta tgtggaggag aaataatgga
    13921 tctcattaca caatacagtg atatcatcct caagaaaatc atgatgaaga ttcagaaaga
    13981 taaaaaagca aaagaacgag cggaattagt taagttggaa atggctgaaa caggagcagg
    14041 agtgcgaagt agcaggcatt ggaaagcagc agcaaacatt gaattttatt acaacgaaat
    14101 tcaaaaaggg ttcgatcaga tgcgtgagct ggatcggcaa acaaattgga gcaagaaact
    14161 tcatcaggat cgtttcaaat ttgtagaaaa gtatagagag atactgaatg agtatttcga
    14221 ggaggactag atgtttaatt caacgttagc gtcaattcac tttttattct atataacgat
    14281 atttgtagct atattaatta atgcgataaa aagcggtttt ttaacaccaa tcggcacaat
    14341 tttaacatta gcttcatttg ttacaagttg tattatccaa cttaaatata taaaggagaa
    14401 tgaataatgg acgaactaat cacaaaagta gagcagtggg ctaaagataa gggattggat
    14461 caagctgatt ccagcaagca aatgttaaaa acgatcgaag agatcgggga agttgccgct
    14521 tctctagcta gaaaagatga acatggttta agagacggaa ttggagatgt agtagtaacc
    14581 ttgattattt tagctatgca aaatgatatg gatttgtacg agtgtctgaa ccaagcatac
    14641 aacgaaatca aaggacgcac aggaaaaatg gtagatggtg tattcgtgaa gtcgagtgat
    14701 ttggaggaca gcaaatgatc agcctaacaa tattttggtg tgtaattggc ggcttactag
    14761 cgatgttagg agcatacctc atttacgaga gtgcaaaagg caaaaaatat acagcagtag
    14821 ggattatttt gtttgttgtc ggaattttag ttgcgattgg tgcagaaata aatctttatt
    14881 taaacggtac gacagaagag ttgatgtggt ttttattgtg gacaaggaga taggaggaca
    14941 gcgaaatggg cgatatgggc gaatactgga aagatattaa accgcatcta aaagaacgta
    15001 gaaaacaaca tgtcagaaag atgggcaatt cagcaactaa aaatattgaa accttgggat
    15061 ttgaatttac tcattatcca aacaatcatc aatttgcaat taatacccat aatggaatta
    15121 ttgactactg gggaactaca ggaacgtgga ttgagcgcaa aacaaaaaaa cgtggtaaag
    15181 ggatacgtag tttgaggaaa tatattaatc aggaggacag caaatgaact atacacaaca
    15241 agaactgact gatttatgtc caaaacatgt agctgagttc atcaataatg aagtcctgcc
    15301 taaatatgca gatggtttaa atacagcaga aaacgttaca gattttatga ttaatgatgc
    15361 tattgatcgt ttgatatttt tagaaataga ttgtattgct tattatcgtc tacacgcaga
    15421 agttgctttg attgatccgt atattgcttt aagccaaaat cgaaaaatac tcgtagccta
    15481 tattgatacc aaacagattt tagaaggcag agatgtcgag atagagatcg atgaggagga
    15541 agtgggatga aagcatacac aatcaagttt tatggaaata aaacctatgt atacatccta
    15601 agcggtctca gacttgattt tagaggctat tcaaaagaag accttttaga atccttatat
    15661 ggttacggat atttaaatga agatgaacta ataagcttag agaaatttac aaatgcttgg
    15721 acgattgagg aggaagcaga atgaagattt atgtagtaaa gttcgggaat aaattttata
    15781 gaagtgatga acgctctata ggggctaaca cattattcat tgtagacata ctccaaagtg
    15841 cgagatggtt tgatagcctc gaagaagcta accaagtttc acgacgactt ggtggattaa
    15901 cacaagtata tgaactggtc actgtcgatc atgaggaggt agaaagatga aattaaaaga
    15961 cggattttac gctagtagtc atggtatcgg cggtttaatg ctagatatgc cgacaaagaa
    16021 tcctaaaaaa cgtaagaaac caaaattcaa agtcggtgac atggttcgct gcgaagcaga
    16081 agggttcatc tatccatttc gtggatatgt agaacacgtc tataatcact cagcgatcat
    16141 tcgtattgaa aacacgatgg aatgtgataa gtggttagcg aaaagcaaag agaatttagc
    16201 tgtagcgaga ttggtggata tgaaggctat ataaacagcg aaaaaatgta cttctaagag
    16261 aaaaatttat tttttataaa aataggaaag tatcattatg aaaaagacca cagagataaa
    16321 taaacctacc acataaaaaa tgaatatttc ttgcgattca atataggtat atttaacaat
    16381 ttgtacaata aaaaatacta taggtaaaaa agataacatg aggagcttat ttgttctaga
    16441 gtgtttgaca aagtaacaaa atgcgacgat accaatacaa acgggaatcc aaaataacag
    16501 catgctccac atagtcactc aaccatctcc tatacgcttt attatcaata gataatatca
    16561 tttttcgtaa taaagataaa aaaataagta aggcttctca ttaaaatata aaaaagacag
    16621 ccgaccactg gctgtcctta gcagaatatt gaaatagtga gccatctgtt ttccgccaga
    16681 tagctcaaca tgtatatggg taacgagtgc aacctcgcta cttgaaaagc ttagcataag
    16741 catgggtata aaaaaagccg gattcctccg accttaatta ataattctga cacaattatt
    16801 atatcataaa tggaggaatc aatggatggt acttttcgat gtaaagaagt atgagacacc
    16861 agaggcaaaa gatgtggata tggatcgcac aaaacataat gttggtgttt ttctttcagc
    16921 atatctgtca gctagatgta ggataggtca acctcgggag cctaaagtaa cggcatctta
    16981 ctccttggtt ccaccttcta cagcaaataa tacatttgaa gcagaacgaa tgatgattga
    17041 gagagaggaa gcgcaagaag aatttgagta cttgcacaaa ttatttgttc gtggctattc
    17101 agcaattcag catccgcata aacctgatgt aacagaaagg cgcaagaaga tattctatga
    17161 tcgttatatc aatggtctgc ccatttatgt aactgctcaa aggaataata ctagcgaaga
    17221 atcggttaaa gtagaatcaa acagaattat catccaattt gcttcatcgt tagaactggt
    17281 tgcttttaag tagccagttt ttacactttt tatacccttt gattacccat ttggtttcca
    17341 ttttatacct tttttatacc aatcacttac ctggtaaatg atttattatg
//
LOCUS       DAFLWC010000063        16909 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.064, whole genome shotgun sequence.
ACCESSION   DAFLWC010000063 DAFLWC010000000
VERSION     DAFLWC010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16909
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.064"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            111..518
                     /locus_tag="L1V17_001980"
     CDS             111..518
                     /locus_tag="L1V17_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236734.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            532..933
                     /locus_tag="L1V17_001981"
     CDS             532..933
                     /locus_tag="L1V17_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236735.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            935..1306
                     /locus_tag="L1V17_001982"
     CDS             935..1306
                     /locus_tag="L1V17_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236736.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1342..1641)
                     /locus_tag="L1V17_001983"
     CDS             complement(1342..1641)
                     /locus_tag="L1V17_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236737.1"
                     /translation="MLFNETQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(1647..1877)
                     /locus_tag="L1V17_001984"
     CDS             complement(1647..1877)
                     /locus_tag="L1V17_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236738.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            complement(2313..2879)
                     /locus_tag="L1V17_001985"
     CDS             complement(2313..2879)
                     /locus_tag="L1V17_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBN1236739.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(2879..3835)
                     /locus_tag="L1V17_001986"
     CDS             complement(2879..3835)
                     /locus_tag="L1V17_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBN1236740.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(3835..4491)
                     /locus_tag="L1V17_001987"
     CDS             complement(3835..4491)
                     /locus_tag="L1V17_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBN1236741.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            4861..6879
                     /locus_tag="L1V17_001988"
     CDS             4861..6879
                     /locus_tag="L1V17_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBN1236742.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    6949..7155
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            7306..9720
                     /locus_tag="L1V17_001989"
     CDS             7306..9720
                     /locus_tag="L1V17_001989"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBN1236743.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            10068..11621
                     /locus_tag="L1V17_001990"
     CDS             10068..11621
                     /locus_tag="L1V17_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBN1236744.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(12002..13786)
                     /locus_tag="L1V17_001991"
     CDS             complement(12002..13786)
                     /locus_tag="L1V17_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1236745.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(13801..15522)
                     /locus_tag="L1V17_001992"
     CDS             complement(13801..15522)
                     /locus_tag="L1V17_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1236746.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            15622..16384
                     /locus_tag="L1V17_001993"
                     /pseudo
     CDS             15622..16384
                     /locus_tag="L1V17_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
BASE COUNT         5581 a         3010 c         3277 g         5041 t
ORIGIN      
        1 aattagctaa tatttccgtt gacaaagctt tgttactatt gttaaactaa attgactagc
       61 aaaagtgaaa cataaattta ttaaataaat gtaaaaatta ggagaaatca atgtcttata
      121 gagtacaatt aataatttca gaagatgtag aaagtcagca atttggcact aatgttatta
      181 ataaagtaat taatccagct ctttctatta atgcgccttt aattcctact gctttatcat
      241 tttctgtaac agctgtggtg tctgagatag aggatacaga aaagataaaa atagtagaaa
      301 ttgaagtttt aaacaagaat gaaaaacaaa ttttttctac gggtgaagta tcggtaagct
      361 tgcctcctca agttaacgat ataaacttta atataaacgc cagaaatgtc ttggttgaag
      421 aagcaggaga gcattatgct gttgttaaat ttaatggaac tgagattgga aggcaaatct
      481 ttgatatcaa ggtcaacaaa ccagtggaaa aaaattaagg agacgatacg gatgcttgat
      541 atagtaccat caaatacaca tcggagtggt agcttaataa attttgctgc gatttttgct
      601 tgcgcatcgg taattctagc atctccagtt gttgtggatg caagttctac tccgaaaact
      661 aaaaatgata atcaacttgt aattactaca aaaaatgaga ttaacacaat ttcaagtaat
      721 gatggcaaaa tttttgatgt gataaatacg gttttaaaaa gaaaagctga aatcaatata
      781 aaatatgatg aagatttaaa cttgtatttc tttgttatca aaacaacatc tgaattgttt
      841 tcctcagatt acgatgtttt ggatactctc gataatgtat tatctgacta taaatatatg
      901 gggaaatctg tagtagcaac tttgggggaa taaaatgttt gactttaatg aatatttatc
      961 tatttccaaa caaattgaat cagatgataa atataattct aaagaatctt atagaagaac
     1021 tgctgtttca agagcatact acagtgcttt taaaaaatct gatgagtatt tgaaagaaaa
     1081 ttatgatatt atttataatg gaagtagcgg aaaaggaagc caccaaaccg tttggaattt
     1141 gttttcaaca gttaaggaat tgaatacctt aggaatacat aatagtgggt atagaatgtt
     1201 agagaaaaga aaatgtgctg actatattcc taatgaaacc attacgaaaa cagatatggc
     1261 gctgatgaat cgagaagcag aaaaaataat aaacaaactc acctaatgaa tttcaagcga
     1321 gtttgtttgt tattttttta tttaatcttt gtatctttct ggatcaacga aagtatactt
     1381 tatatagtca taacgccgat gatcgctacg tgcgtccggc acgtcagtca cgatatcaaa
     1441 caaaaagtat acacccttct tcattctagt tttcgcagca ggaattttga aatagttctt
     1501 attagaatag tagagattga ttaataagct atcttcgatt gctaaaaaga aaacttctga
     1561 attccatact ttataaaaat ctttgataaa tctattcgaa gggtcaaatt taaaccataa
     1621 ttgtgtctca ttaaaaagca taaccattac tccgatctgt ttttaaaatt agtttctacc
     1681 tctaatatat atcgagtttt tattttgcct tcagagaata ctgtttcttt ttttgcagtt
     1741 acaggttgtt tattttcgga aaaagctaat atagctaaga ttgaaacatc catctggaat
     1801 ttatcttttt tactgctttg atcataaaag tctgcatatt catcactgat attttttcta
     1861 ataaattctt ccatcataaa aatcacctca aaacgattat acgaacttac gttcttgttg
     1921 taaagcgata tttgaggggc aaaaaagggg cataatttga ctgatattaa gttagctatt
     1981 gatatatgaa tgacatacaa aaatataaaa tcttttaaaa atgcttatat atcaatgttt
     2041 ttgccattct tttatatatc tgttatatgt caaaaaaatg tgttcaattt caatttgtat
     2101 ttgaataaag aggttgtgaa aaagctgtcc tgcatcaagt aataagaaca gccaatcaaa
     2161 aacagcttct catgtttttg atttggttgg acttattacc gcagatataa gcttttgagc
     2221 accgtgaata aagaggttat gaaatcaacg ctctaacctg agtattagag aaaaaaacgc
     2281 aaaacatatc atttatgttt tgcgtttttt atttatcttt ttttctcaat acaatataaa
     2341 ataggcggct ggttcttttg gttgataaac cgataattca gcacattata tgtttcctgt
     2401 ggcagtttgg aacaaaaaga atcaaccata tccagttctt tttctccacc ttcatgacca
     2461 tagtagacga caaggatcaa tcgtccgcga ggcacaagtc gtttcaatat ttcttccata
     2521 gctgtgcgtg tagtctctgg catagtgatg attgctttat cactttttgg gagataccct
     2581 agattgaaaa tccctgcttt gagattttgt tgttcagcta tcacttctcc taacgtttcg
     2641 tggccttgta gaaacaatga gacacgttct tctaactgac gctgttctag cctttcacga
     2701 gtagcatcga ttgcttgttg ctggatatca aaactataga catgaccagt ttttccgatg
     2761 tgttctgcta gaaaaaccgt atcgtggcca ttgcccatcg ttgcatctac gacgtgatcc
     2821 cctggttgca agatttcttg cagtaatgta tggctgaaat gcaaagcagt ttgcaacatc
     2881 agacgctcac ctttttccgt acatcatatt ttccttggaa gctatctctg cgaagaagtt
     2941 cttcatcaat tgcattcaag acttcccatt ttttcaagct ccacattggt ccaatcaagg
     3001 aatcccacgg cgcatcccct gtcaaacgat ggatgatgat ctcttttggt atcatttcca
     3061 gctggtcgca aatgacattg acatagtcag gacggctcat taattgaagg cgaccttcat
     3121 gatagtcccg caacattctc gttttgcgca tcagatgcat caaatggagc ttgattcctt
     3181 ggatatctga atctaaaatg gtgcgtctga cattttcttt catcatttct aaactttcgc
     3241 ctggtaatcc gttgatcaaa tgcgtacaaa cacggatatt atgtttgcgt aatttagcca
     3301 cgccatctaa ataagtttga taatcatgtg ctcggttgat cagttttgaa gtttcttcaa
     3361 aagttgtttg caatccaagt tctacccata aatacatccg ctcgttcagt tcagcaaggt
     3421 aatcaactac ttcatctggc agacaatccg gtcgtgtacc gactgataat cctacgacac
     3481 ctggtaaatt gactacttgc tcaaatcgtt ctttgattat ttcaactggc gcatgggtgt
     3541 ttgtaaaatt ttggaaataa acgatgtatt gttggacatg aggccatttt tgatgcatca
     3601 tgtcgatttc tttctggaat tggattggaa gagggtcttc aggtgcaacg atcatgtctc
     3661 ccgaaccaga tacactgcaa aaagtacaac cgccatgggc aacagtccca tctcgattcg
     3721 gacagtcaaa tcctccatcg atcggcacct tgaaaatttt cccgccaaac tcatttcgta
     3781 aagcgtaatt ccaagaatga tatcttttat ttccttctga ataaggaaaa gtcattaaaa
     3841 gtccttcttt ctgtaagagt tatctatttg ttttcttttt tctctataca ctggataagt
     3901 caggcacagc caagaaagac tgagtaagta accgccgatg atatcagtag gaaaatgaac
     3961 gcccagataa atgcggctta tcccgacact tactataata aacatcatca gcaattgaag
     4021 caatgtgcgt aaggttcttt tttgaacaaa agctggaagc agaaatagta aagaaccgta
     4081 aagaatcata ctgcctgctg catgtccact agggaaactg taacttgttt caactactaa
     4141 gtgcgccaat gaaggacgct ctcgcatgaa aaatagtttg atcaccgggt tgatgattcc
     4201 agcaattaca ataaatccag aaacgaacca aaatgtttct gccctttttt tcttatacca
     4261 catccataaa gccgcacaag caaataaaat gatgacggta agaggattac cgaatttagt
     4321 cataaagagt tggtagctgt tcagatcagg ataagaagct ctgacaatgc ctgtaaacca
     4381 ctgatcgaaa ccagaaagcc acgacagatg gaactttacg atccagccca aaatgaaaaa
     4441 caggacaaga aagaagctac cagccacctg aaatgatgtt ttatatttca tacaattcct
     4501 cctttgaagc aatgacttat tatagcattt ttggtccagc gaaaaaaacg gtaaagagat
     4561 aaaaccaatg tatgattcct ctttgaataa ccaatattct tataaaaaaa ataactgtaa
     4621 tcggaaagac attttttggt aatgcaaatg aaatgttagg gaaataaaat cagtgttttt
     4681 cgaaatcctt ttaaacaaga acgtagacgt aggaagaact tgaaaatgaa cagaagttgt
     4741 tcattacggt aaattacaat atgattacaa aaaacaacaa agctcttaaa taacttttaa
     4801 taaatattaa gagaagttat aattattaat aatagataaa ttgaagttgg aggatagaag
     4861 atggaaaaca ttgcaagaaa agaacggaga cgtttagaac agaccaaacg ttttcgaaaa
     4921 gcaaaacgag gggcagcaat cgtgggaact gcgatggtag gctgttctgt cgctgcccca
     4981 ttagtacagc cggttcctgt tcaagcggat gaaacacctg ttcagttcgg cgcaagaatc
     5041 aatacagcgg catttatcac agaaattgct acttatgctc aaccaatcgc tcaagccaac
     5101 gatctatatg catcagtgat gatcgcacaa gcagttgtag aaagcggttg gggcagtagt
     5161 gcgttatctc aagcacctta ttataatctt tttgggataa aaggcagcta tcaaggacaa
     5221 accgtctaca tggatacgct tgaattttta aataatcaat gggtaaataa aaaggagcct
     5281 ttccgacaat atccttcttt tgctgaatct ttcaatgaca atgcctatgt acttagaaat
     5341 acttcatttg gcaacggtta ttactatgcc ggtacttgga agagcaacac gaaatcctat
     5401 acagatgcga cagcttgttt gacagggcgt tatgcgactg atcctggtta cgcaggcaaa
     5461 ttaaataata tcatcgcaac ttacggattg acccaatatg atacaccagc tagcggaaac
     5521 gcaggcggtg gagcgactac aggtggcaat aatactggaa gtgcaggtag tactggcggt
     5581 tcaagcaatt ctggtaatac aaactcaggt tcagcaactt cgaccactta tactgtccaa
     5641 tctggtgatt ctgtttgggg aatctcaaat aaattcggta tcacaatgga tcaattgatc
     5701 caatggaaca acatccaaaa caatttcatt tatccaggac aaaaactgac aatcaaaggt
     5761 agccaggaaa atggctcttc gacgaataat tccggtaaca ataccaattc ttcaggaaat
     5821 gctggtacat caaacggagg acaaacaact ggtgcgaaat acactgttca atctggtgat
     5881 tctgtttgga agatctcaaa tgatcacgga attacgatgg ctcaattgat tgaatggaac
     5941 aatatcaaga acaatttcgt ttatccagga caacagctaa tcgtatcaaa tggcggttct
     6001 tctaatgctg gagcaaatac tggctcaaat actgggaata caagtggctc tagttcgtcc
     6061 agctcaagtt cttctaatac agcttcagga acgaaatata cagttaaagc cggagactct
     6121 gtttggagcg tctcaaataa atacggaatt acgatggctc agctaatcca atggaacaat
     6181 atccaaaata actttatcta cccaggacaa caactgactg tttcaaacag tggatcaaca
     6241 aacagcacgt caggtaatac aggttcgtca accaatacaa ataacagcag ttcagttaat
     6301 actggcagca gttcgtctca aggcacttat accgtgaaag caggtgaatc tgtttggagc
     6361 gtggcaaata aaaacggcat cacgatggat cagttaatcg aatggaataa tatcaaaaac
     6421 aacttcattt atccaggaca gcaattgatc gttaaaggtg gaacttcggc aaatacaaat
     6481 acaggttcaa ctacttctgc agcgaaacca aatacaccga atacgtctgc tacgacaagt
     6541 acatcatcca ctggtaatac gatgtatacc gtgaaagcgg gcgagtcagt ttggagcgta
     6601 gcgaacaaac atcatatcac gatggatcag ttaatcgaat ggaataatat caaaaataat
     6661 ttcatctatc caggacagca agtgattgtg aagaaaggtt catctcaatc aacaaaccaa
     6721 caatcagtta ctggttcgaa aacctatact gtgaaatctg gagaatctgt ttggagtgtt
     6781 gctgacagtc atggaattac aatggctcaa ctaatcgaat ggaacaatat taagaacaac
     6841 tttatttatc caggtcaaac gttgattgta gctaaataaa atagctgttc gaagaaataa
     6901 cgattgaatt ccacaaaaat atttgttact ataaggctac ttaaatatga caacacttga
     6961 aaaggaagta gtaaaaagac tgaagtttca gagagcgcat ggctggtgag aatgtgcacg
     7021 gatgcttttg aactcgcctt tgagttgccc ttgctgaata cccgagtaag caagcggcgg
     7081 tgacggccgt tacaacgttc gaggcctttt cactaaggta aaattaggtg gtaccgcgta
     7141 gattacgtcc tataaaaaga gcaatctttt tataggattt ttttatttct tttgtgaagt
     7201 ttgagaaaac aaagcaaaag gaaataaaaa taaacagatt ctgccggttt tttcgttata
     7261 tttataatag aaacaagtgt tttcaataga acaggaggac agcaaatgag ttacaatcat
     7321 aaagaaattg agaaaaaatg gcaaaaatac tgggcaaaaa cgaatacttt caacacccat
     7381 gatgatcctg aaaagccaaa attttacgca ctggatatgt ttccctatcc atccggtcaa
     7441 gggctacatg tagggcatcc tgaaggttat acggcaacgg atatcctttc acgtgtgaaa
     7501 agaagtcaag gatacaacgt gctgcatcca atggggtggg atgcattcgg tctgcctgct
     7561 gaacaatatg cgctagatac aggaaacgat ccagctgagt ttacccaaaa aaatatcgaa
     7621 acattccgac gccaaatcaa ttctttagga tttagttatg actggaatcg cgaagtgaat
     7681 acaactgatc cggagtatta taaatggaca caatggatct ttacgaagct ttatgaaaaa
     7741 ggtctagctt atgaagcaga agtagcggta aactgggtac ctgaattagg aacagttatt
     7801 tcaaatgaag aagtgatcga tgggaaaagt gaacgtggtg gctatgatgt agtcagaaaa
     7861 ccaatgcgcc aatggatgct gaaaatcact gcttatgctg atcgcttatt ggatgatcta
     7921 gaattagttg attggccaga aagcattaaa gaaatgcaaa gaaattggat cggtcgttca
     7981 gtaggagcaa atattgaatt taaagtggct ggtacggata aatcctatac cgtatttacg
     8041 acacgaccag atactctatt cggtgcaact tactcggttc ttgcacctga actagatctt
     8101 gttagagaaa ttacgacccc tgaacaaaaa gctgctgtag aagcttatat cgaagagaca
     8161 gctaaaaaat cagatctaaa gagaacggat cttgcaaaag aaaaaacagg agtatttact
     8221 ggtgcttatg caatcaatcc agttaatggc aaggaaatcc caatctggat cgccgattat
     8281 gtattatctt catacggcac aggagccatc atggctgttc cagcacatga tgaacgtgac
     8341 tttgaattcg ctcaaacttt cggactagaa attcttccag ttatcgaagg tggagatgtt
     8401 gaaaaagctg cttacacaga agatggtacg cacatcaact ctgaatttct agacggcatg
     8461 aacaaacaag aagcaatcga taaaatgaat gaatggctag aagaaaatgg cgtagggaaa
     8521 aaagaagtca gctatcgctt acgtgactgg ctattctccc gtcaacgtta ctggggtgaa
     8581 ccaatcccaa tcatccattg ggaggacgga acagtcacag ctgtcccaga agaagagcta
     8641 ccattacggt tgcctaagac aaaaaacatc aagccaagcg gtactggaga atctccatta
     8701 gcaaatatcg aggagtgggt caatgtcgtt gatcctgtaa caggtaaaaa aggccgtcgc
     8761 gaaacgaata caatgccaca atgggcagga agctcatggt attacctgcg ttatatcgac
     8821 cctcataaca aaaaagaact agcagattat gaaaagttga agcgttggct accagttgac
     8881 atctacattg gtggagcaga acatgcggta cttcatttac tatatgcacg attctggcat
     8941 aaattcttat acgatatcgg tgttgttcct acaaaagaac cattccaaaa actatacaat
     9001 caaggaatga tcttaggcga aaacaacgaa aaaatgtcaa aatctcgtgg taatgtagtc
     9061 aatcctgatg atgtggtcga aacttacggt gcagatacac tgcgcatgta cgaaatgttc
     9121 atggggccat tagatgcttc gattgcttgg agcgaaaatg gcttagaagg aagccgtaaa
     9181 ttcttggatc gtgtatggcg tttgatcgtt gatgagaaca ataaaatgcg tgaccgtatc
     9241 actacattga atgatggcaa gcttgataaa gtgtatcatc aaacagtgaa aaaagtgaca
     9301 gaagactatg aaaatcttca tttcaataca gcaatctccc aattgatggt ctttatcaat
     9361 gaagcctata aagtggacgc tctgccttat gaatatatcg aaggatttgt tcaactactc
     9421 gcaccgattg ctcctcacat gggtgaagaa ctatgggcaa tccttggaaa tgatggtggt
     9481 atttcttacg caccatggcc aacatacgat gaagcagcac ttgttgaaga cgaagtagaa
     9541 gttgttttcc aagtaaacgg taaagttcgt gcgaaaagca atgttccccg agacttagga
     9601 aaagatgagc tagaaaaagc agcattagcc aatgaaatag tgcaagaata tattgaaggc
     9661 aaaacagtca gaaaagttat tgcggtacca aacaagttag tcaatatcgt tgctaattaa
     9721 ttggctcttt gtcaataagg actgatgagt tgtgcaaaat caaatctggg ccagaatgaa
     9781 cttcattctg tctcagattt tttgttattt caaattgatt aattgattga tcaaaaaggt
     9841 tttgattttc atgttctcaa acacgttcaa tgtctttttc ttctgaatgg tcttgtaaga
     9901 gatctctgta atcatcaaat ttttgtctat taatcttagt attttttgat gtataaacta
     9961 cctgaaattg agagtacata ccaaattcat aaatttttta ttagtgggac tagtgattgt
    10021 atggattttg acgcataatg aatgaagtat gagaaaagga gagacaaatg gatcaagaac
    10081 tatttattat cgaagtatta tcagctaaac aaaaaattat cgagaaagcg aaaaaaagag
    10141 cgaaaagaat aatgttcaag cttttaagct tagtattttt ctctggtttg ctttttttcg
    10201 gagctgtatc gttcctatat cgccatatga gtgcagtagt ccgttcagct gaagggatgc
    10261 aaaaattaaa taatttgtat cacttttcgt ggggagttgg cggaataaca attgttgtgc
    10321 ttattgtttt tcttctactt atttggctcc gttaccatca attgtcgcgt catttcgatc
    10381 aatggcttag tcaaagagca caacagtttt tacataataa accaacttct caagatgatg
    10441 actatcttta ttttgagaag acttcgacga gtcaagcttt tcggatacaa aaaagtgatt
    10501 gccagttatt gctgagatca cttgatgatt tacctatcta cttaggcgaa agcaaatcaa
    10561 aattcggaat gaacacattc catatttttt tactagaaaa cgaacccaga tgggaaaaaa
    10621 gccagtcttc gcctggtgga tacctgacaa ctaagatgag tacattagtc actggttttt
    10681 tcctcattct tttagctgga acaatctatt atgggagata cactcagcca aaaatgtctt
    10741 ctcatataaa tgctgcttct cacatgacaa tgaactcaac taacgatacg catatacaaa
    10801 agacaaatga agggttgtta gctgatccta agcaaaaggt aaatttgaca acacaaaaga
    10861 taaatgatct caaacttgat acagagacgc actctctcta tatgacaaca gatagtggtg
    10921 ctaattgggt atttgtgccg attgattcgc aatggttgcg ttttggcgaa tacaccctga
    10981 caacggggct gattcctgaa ggttattgga tggacaacac atatgatatt tccgccgatt
    11041 tctcatggtt tatctattct tctggggatg atgtacgtct gctgacttca agagataatg
    11101 gtaaaacatg gcaaacgtct attatcaccc aatcagttca gccgatacgt tatcgaaaag
    11161 cggtatttta tggcaacgat ggtctattta tctgtacatc agccagtggg atgtctgcag
    11221 aaactttgta catttacact actatggatg gcggaatcac ttggataaaa agtggaagta
    11281 caatgatcaa tcagccagta caaaatgtca gcttcgttac aacttcttta ggttttgttt
    11341 cgacacgtga aagtttgttt tatacaaaca acggaggacg ctcattcaaa gaatcagttc
    11401 tgtcgattcc ggaaaactat cagacagggg ggatagatct ttttcaatca ccaaatgaag
    11461 ttactcaaat aagcgcgaat acgttagaga caaaatttta tttgttgaaa aaaggaccaa
    11521 tcgatgcagg gaaaatgttt gcctgcctct tccgttcaac tgataacggg gaaacatggc
    11581 aattcgttca gcaactatcg caagtagaac aaggagatta aagaagagag attgtgagcc
    11641 tgacgttcag caccgagtca caagaaacaa attcaaaaaa cagcttctca tatttgttga
    11701 atagtgtaac tcgtgattcg gagttgacaa gagcaacaag aagcgatttt gaagtatagc
    11761 ttctcgtatt ttacaagatc gtgtcttatt gccgataggt tgtctcttga acaccgttta
    11821 ttcgtaaaaa gggattgtga caagtctttt gtcactactt accgaacgaa actgaaggag
    11881 ctatccaaaa agtatcatta gtattattct ttgtgtttct agtggcacca ctagtacatt
    11941 taaaaaagct atcgatcatg gactaatcat acatgatcga tagcttttta gataatgttt
    12001 gttacgctat ctgaaattga ctattataaa gactggcata aagcgttggt gattggagta
    12061 gttcagaatg tgttcctttt tcgacgatat cgccattctt cattacaagg atcatgtctg
    12121 cattttcaat cgttgacaaa cggtgtgcaa tcacaaaact tgtcctatct tttgtcacag
    12181 cttccattgc ttgctgaatc aatgcttctg ttcgtgtatc tacgctagaa gttgcttcat
    12241 ctaaaataac gacaggagga ttcgctagaa tgactcgagc aattgtcaat aattgttgct
    12301 gtccttgaga taacgtgccg ttttcgctag aaatgatcgt atcatatccg tctggcagtg
    12361 ttcgaataaa gtgatcacat tgtgcgattt cagccgcttc gataatttgt tctcttgtgg
    12421 catccatttt cccgtaggcg atattatcag ctaccgttcc ttcaaacagc caggtatttt
    12481 gtaaaaccat cccaaaagaa cgacgtagtt ctccacgtga aagcttggta atatcaagac
    12541 cgtcgaattc gatctttcct ttattcagtt cataaaaacg catcagcaga ttgactaaag
    12601 tcgtttttcc tgcaccagtt ggaccaacga tcgctaccgt ttgttttggc tttactgaaa
    12661 aatcgacttg attcatcaat attttatctg atgtgtaacc aaactgtaca tttttgaaag
    12721 ctatttttcc tttcggttgt tctaaaagtc ttgcatctgg aaggtctgga atttcatctg
    12781 tttcatctaa tatctcaaat atcctatcga ttgctgccat tgcggattgg atcgagttga
    12841 tcacataaga agcggtagaa attggttcag aaatctgatt gatgtactga agataagctt
    12901 gtaagaagcc gatcgtcaca ccacctgata gaacaagcat agcaccgaat accgcactta
    12961 tgatgaaggc gagttgatta atgaaacgaa tggccggata gatagcacag ttcataaatt
    13021 gagcacgttt aaaagcgttg tattgctttt tatttacttc gtgtatagca gcttctgcat
    13081 gagcttgctg attgaatgtt ttgaccacta gattaccagc taagatttct tccattcgat
    13141 tatttaaaac acccagttca tactgattct gttcagaaat ctgtttgttt ttgttcgcaa
    13201 tcttagttgt aacaattgaa ctgccaacga tcagcaataa gacgagcaaa gtaagcttgc
    13261 tttcgatata aaacagcatc agaccagcag cagctattgt tacgacagaa gtaaaaaatt
    13321 gattgatacc tgtcaataac acttgagaaa gttgattgag accggtagtt gtccgactaa
    13381 tgatgtcacc tacttgatga ttgtcaaaaa acgacatcgg taatgttttg aatttttttg
    13441 tgatttcttt tcgcaccctc aatgtgatct tttcgcttaa cgctgccatt gtccgttcct
    13501 gaataaatga agtgatgctg cttaagactg aacagccgat cagcaataag acagggaaca
    13561 acaatgcttg tttgatatca ctgaaagaaa gctgtccaat acctgttttt cttatttctg
    13621 ataagagatc atcgatcccg attcccatga tcaagggcat ggctacgact aataggttcc
    13681 cgaataaact gcatagaaac aatccgtaaa aatatttatg ttcaggtttg atcattttcc
    13741 aaaaacgtat caaagcacgc gtgttcaacg tttttttctt ttccatcgta tcccttcttt
    13801 ctatattcct tgtgattttg caaactcctg ataagtttgg caattagaca gtagttcttc
    13861 atgagtacct tgtccaacga tttttccttc atctaaaaca atgatgttat ctgcttgttg
    13921 gattgtactg aggcgttgag caacaatcac gagagttttc tccgacatgt gtttatgaag
    13981 ggctgctctt aatgctgcat ctgttttata gtctaaagcg gagaaactat catcgaatac
    14041 atagatctct gctggtttga tcaacgctcg agcaatacat atccgctgtt tctggccccc
    14101 tgaataatta gaaccgcctt gagcaacaaa gctgtccaat ccgtcaggaa gggtgtccac
    14161 tagttcttct aattgagcga tcttgatcgc tttagacaac tcttctgttg aggcatattc
    14221 atttcccatc tgcaagttgc ttaaaattgt cccgctgaat aagaaagcct tctgagggac
    14281 ataactgatg tgggagcgga tctgttcttg agtcatttga gtaagaggaa taccaccaag
    14341 ggttactttt cctatcgtag ggtcactaag tctcaagaga agtttcgcca aactactttt
    14401 tccagatccg gtcccgccaa cgatcgctgt tgtttttcct ttaggtattg tgaaatcaat
    14461 atcttctaga actggatcag agatttcagt atatttaaat gtgacatgtt caaaagcagc
    14521 tgcatttgtc tgatcaaagg ttggttcagc tactgttttg atcgtctctt cctcaatttc
    14581 gatctctgct tgcagtattt cttctatccg tcgtaatgag gcaaacgatt tagggataat
    14641 gaccaatacc atagctgcga tcatcaagta agcaagtgtc agcatagagt attcgactac
    14701 agcagtcacg acaccgattt gtaatgctcc ttctgctaca agatttccgc caaaccacaa
    14761 aatagaagca taaacgattc ccatgagcaa aaaagcaatt ggagtgaccc aagcaaatat
    14821 tcggttcact ttgatcattt gattagcata gtcagcaaag ctcttattcg ttcgcttttc
    14881 ttcatatgat tgattatcaa aggcacggat catattaatc ccagtaaaga attctctcaa
    14941 tgtgatggtg atccgatcca tttttggctg gatactcaaa gataaaggtg cccctcgttt
    15001 catcagtcga taaacaatcc atacataaaa aacaacagag atcaatgtaa cccatgttag
    15061 taatagagaa taacgaaaca tcatgagaat ggtgaaaacg caaataaccg gtgctggtaa
    15121 gatcatttgg caaaataaaa caatcatttg ctggacatta tcgacatcat tcgtcattct
    15181 tgtcaaaaga gatccagaac taaaacgact gatatccttc attgacagct gttggaattt
    15241 acggaaatat ttctcccgcg tttggaatcc aaacctagcg gaagccaatg ctgaaaagta
    15301 actagaggca actgcagcga ttgttcctag aaacgctaca agcagcattt caactccaat
    15361 tttttttata actgaggctt cgccacttgc tatacctgtg tcgatcagct ttgctactaa
    15421 ttttggtaca cctaatgtac cggcgatttc taaacagatc atcacaaagg taaggagagc
    15481 gagtcctttg tttttctgta agaatgtttt taagatagac atattattcc tccttttttc
    15541 ctgatacttt tcgattctat accttcaagt aacttgaagg tcaatagaaa aaagaataaa
    15601 ctgaaaaaga ggtgagaaaa aatgaaaaaa atgtatacga ttggccaagt atcggaacta
    15661 tttgatttgc caaaatcaac gatccgctat tgggatgaac aaggattaat ccgttcaagt
    15721 agacaagaag agaatgatta tcgattgttt gatatcgatg atatttttat gctttatgat
    15781 atcgtttttt atagaaaatt agatataccg atcaaacaga tgaagaattt atatggaaaa
    15841 acattgacgg agttatatga gacacttgat gaaacagaaa gaagaatcca taaagaactg
    15901 gtggtgatga aacaaaaaca aaaagagata agggagcaaa aaaaaacagt tgaaattgat
    15961 gatcgataca aacgaggaag aatttcctgt agaagagatc ccttttgact gtatgatctc
    16021 aacggagttt gaagatattg tggaaatcaa aaaatttcta cctaactatt caagctttgg
    16081 gatgatgagt atgccagctt ccagttcaca gacgatgtat ggatttttta tcgaccctag
    16141 tgaagtacat ttatttactc aagacgtgat ttgggagaaa aaagatacgg ctgtttatcg
    16201 tcgattctta ttgaaatccg agatgaacca tgcggaacgt aataatattt tagaaatcag
    16261 agaaagaatg tatgaaaaag gatggaaaac aggagaagtg atcggccagt atctattgac
    16321 gaatacggat gaaaacaata tcagaactga atattatcat gcatggatag aaatgaaaaa
    16381 ataggaaata tgtgtttaag ataactcgaa aatgatggtt gttttagtta taaagaaaaa
    16441 ttttctggtt cgattacggg tttaatgtgg gggattatta gtcgtggata gatagaattt
    16501 tagtttttta gaggaaatat gtctttaaaa atggaatggt tgcaattctt agcgatatat
    16561 acgatgtaat tgtcctctta aaaaagtatg gaaaaataat tgtattgggt gttatgtata
    16621 attcatggtg aactgagact aatgagaaga aaaattcata ttgttatgag tgagattgta
    16681 tcagatgaga atgataaatt aaataggtgc ataaaagcat tacacttaaa atacattgtt
    16741 gcttacatta ttacaatatg ttaataaggc aaaaataaat agatggattg aataaacata
    16801 ttttttaatc aaatagtccc tactgtgact ttcctcagct atcggtgata ctaccgatag
    16861 catttttttg cttataaaat aattataagt atttagagat ttttcttct
//
LOCUS       DAFLWC010000064        16770 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.065, whole genome shotgun sequence.
ACCESSION   DAFLWC010000064 DAFLWC010000000
VERSION     DAFLWC010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16770
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.065"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..304)
                     /locus_tag="L1V17_001994"
     CDS             complement(<1..304)
                     /locus_tag="L1V17_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBN1236747.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKS"
     gene            complement(306..503)
                     /locus_tag="L1V17_001995"
     CDS             complement(306..503)
                     /locus_tag="L1V17_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HBN1236748.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(897..2624)
                     /locus_tag="L1V17_001996"
     CDS             complement(897..2624)
                     /locus_tag="L1V17_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HBN1236749.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2617..3810)
                     /locus_tag="L1V17_001997"
     CDS             complement(2617..3810)
                     /locus_tag="L1V17_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HBN1236750.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(3997..4641)
                     /locus_tag="L1V17_001998"
     CDS             complement(3997..4641)
                     /locus_tag="L1V17_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1236751.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4735..4869)
                     /locus_tag="L1V17_001999"
     CDS             complement(4735..4869)
                     /locus_tag="L1V17_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBN1236752.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(4871..7003)
                     /gene="feoB"
                     /locus_tag="L1V17_002000"
     CDS             complement(4871..7003)
                     /gene="feoB"
                     /locus_tag="L1V17_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBN1236753.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7000..7473)
                     /locus_tag="L1V17_002001"
     CDS             complement(7000..7473)
                     /locus_tag="L1V17_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBN1236754.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            7874..8098
                     /gene="nrdH"
                     /locus_tag="L1V17_002002"
     CDS             7874..8098
                     /gene="nrdH"
                     /locus_tag="L1V17_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HBN1236755.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8257..10416
                     /gene="nrdE"
                     /locus_tag="L1V17_002003"
     CDS             8257..10416
                     /gene="nrdE"
                     /locus_tag="L1V17_002003"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBN1236756.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10466..11431
                     /gene="nrdF"
                     /locus_tag="L1V17_002004"
     CDS             10466..11431
                     /gene="nrdF"
                     /locus_tag="L1V17_002004"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBN1236757.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11520..12659)
                     /locus_tag="L1V17_002005"
     CDS             complement(11520..12659)
                     /locus_tag="L1V17_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBN1236758.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(12968..13681)
                     /locus_tag="L1V17_002006"
     CDS             complement(12968..13681)
                     /locus_tag="L1V17_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBN1236759.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(13935..14636)
                     /gene="nagB"
                     /locus_tag="L1V17_002007"
     CDS             complement(13935..14636)
                     /gene="nagB"
                     /locus_tag="L1V17_002007"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBN1236760.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            14870..16402
                     /locus_tag="L1V17_002008"
     CDS             14870..16402
                     /locus_tag="L1V17_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBN1236761.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16593..>16770)
                     /locus_tag="L1V17_002009"
     CDS             complement(16593..>16770)
                     /locus_tag="L1V17_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1236762.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5206 a         3452 c         2888 g         5224 t
ORIGIN      
        1 gagatttatc tccataatct gctcgatata aaccatttat tccagcagtt cttccaattt
       61 cactcaaatt tcttattaat tcctcttgat attcagtgaa tcttatttta ttagtataag
      121 cagtaaaata tagataattc accaatctat ttattaaagg actgggatct aattcatatt
      181 tttgtttttc taattttaaa tatacctttt gtaaaacctc aagaatatca gaatatttag
      241 gatctttact tatagatata tcattatata attcatgaac aatttgctta gcattttttt
      301 tcattttagc acttccctgg aattgctcca cctaaaaaac cacctataga cattcctgca
      361 atacaagtag ttgccttggc ccaatcgacc gtacatttat ttttagtgca atacactcca
      421 tttccataat attttccact atgagtggta cccccataga taagttgtgt ctctttaata
      481 gacaaaattt ttaaatgttt cataatctaa tcacccctaa attaatgttt ttagactatt
      541 attctaacat tcattaaatt tcaaaaaaca attccttctt gaaacgtagc aaaataattc
      601 ctgaataaga atttaatcac ttttaagtat ataaactatg tatattcttt aatatttttt
      661 gagaatgcac ttcgtacata ataaacttta atcacattag tctttcatac ctacgatcga
      721 tctctttgac tcgcacccat aaattcataa tagtttgtcg gcgtctttga acgtttcgaa
      781 gatgagctac gcattctctt tttttataga caaaaaagat agagacgaac atggagcttc
      841 caaatttgga tatttgatcc aattttggaa gctccattta tttcgtgtct gtctttttat
      901 tttttccagc tttcgactaa ttcttggttc tctttgatcc agtcttttgc tgcttgctgt
      961 ggatcttttc cattgttgat ttccaacata actttttcca tatctttttc tgaccaatgg
     1021 aaattgtcta atactttgta agcttctggc tggtcttctt tcaatccttt tcgaaccatc
     1081 gtatggatct gctcttcgct tcccattccg ttttcaggat cttctaagta tttcagatca
     1141 tatttggcaa acatccaatg aggtgtccat cctgtaacta caattggttc gtgttttttg
     1201 atcgcttgac ctagtgcaac ggtcattgct cctgaagaag atgtctctac tttccagtct
     1261 ttcaagttgt catatttttg gatcgtgttt tcagcagccg taactacacc agctcctggc
     1321 tcgattccta tgattttctt acctgcctga tcggttaact catcgatcga atttacatcc
     1381 atgtaggctg gcactgctaa accaactttt gctcctgtca aattggcacc taggtcttcg
     1441 acttgatctt tatattgtgc atattgtgaa ccatgagttt taggtagcca agctgaaacc
     1501 atggcatctg actcgccatt tgaaacagat ttccacatga ttgaattatc taatggcgtc
     1561 atcgttacat catagcccat ttgtttcaat acttcaccga ctacatttgt tgaagcaact
     1621 tctgtatccc attcaacata agataagttg atacgttttg tttctttggc agatgaaaaa
     1681 ctccctatac caatcgcacc taagatcact actactacag caccaatgat cagtccttga
     1741 cgttttttac ttttctgtgt tgttgctcct gcagcttttt tattgtttgg ctggttcaaa
     1801 tgctgtgtaa aacggtcaat gatgattgct aagataacta atgcaacccc gttgacaaat
     1861 ccattcccga cttgtgctct ttgcaatgct gataatacgc cgcgtcctaa gccgggtgca
     1921 ccgatcatag aggcaataac gaccattgaa agtgacagca ttgttgtttg attgatccct
     1981 gccatgatcg tacttttagc taaaggcaat tctagtttga atagtttttg acgacttgtg
     2041 ctcccgaatg aatcagaagc ttctactaat tctttaggaa cttgtcgaat ccctaaattc
     2101 gtaaaacgaa cggttggtgg cagagcaaag atgactgagg caaatacccc tggaaccatc
     2161 ccgataccga aaaatgcaac tgctggaatc aaataaacga atcctggcat tgtctgcata
     2221 aagtcaagga tcggtttgat aatactttgg gctttactgc tttttgccat caagatccct
     2281 aatggtaccc caatgatgat cgagatcaca ctagataaaa gaacaagtgt gacagtattc
     2341 atcaaatcat tccatagacc ttggttataa ataaaccata gaccgattaa tgtgaacaac
     2401 gtaagtcctg gacgtttctt agaaataaag aaagctgcta ccgtcaataa caagataaac
     2461 aaaggagctg gaatcactaa cagtaaattt gtaatccccg acatcactgc ctgtccaatc
     2521 gtttgtaaaa atgaaaatag gccagaaaaa gttgtcgtaa accattctgt gatattttct
     2581 acccagtttg ccactggtaa ttgatagttc aatagattat tcatgttcac tcacctcgct
     2641 tgtttctgct aatgcttcaa tcacactacc tcggatgacg acacctttta attttccatc
     2701 ctctacaact gcaagtggag tcggtgagtc ataaataata ttgaaaatat cacttaccac
     2761 catgtctttc ccaatcaccg tcacattttc atctaggaag tcgatcaatg gacgtttttg
     2821 cttcctagct tctaacgctt gatctgcagt gatgatccct ttcaggtgtc tctttctgtc
     2881 aacagccatc agcatgctga cttcttcatt acgcatcctt gtcaatgcaa cgtttggtcc
     2941 atcagattcg atattcgtcg tcaatgcagg taccatgatg ttttgagccg taagcacttt
     3001 ggaacgatcg acttcttcca caaattcacg tacataatca tttgctggat tggtcaatat
     3061 ttcttcacct gttccgatct gcatgatttc gccgtctttc atcaaggcga ttctgtcccc
     3121 aatccgtaaa gcttcattca aatcatgggt aatgaaaata atcgtttttt gaacattggc
     3181 ttgcaggtcc agtaattcgt cttgcatttc tcgccggatc agcggatcaa gagccgagaa
     3241 cgcttcgtcc atcagcaaga tctcaggatc atttgctaaa gctctggcta ggccaacccg
     3301 ttgttgcatc ccaccagata actgactagg atattggtct ttaaatgaaa gcaaactaga
     3361 attttctaat gctttttctg ctttttcttg tcgttcttct ttaggtacac cacggacttc
     3421 taacccgtat tctgtatttt ccaagatcgt tcgatgtgga aacagaccga agttttggaa
     3481 aaccatattg attttatgac gacggacttc tcgcaattct tctttgctta acttcgatac
     3541 atcttctcca tcaatataga tactgcccga agttggctca atcagacgat tcaatagacg
     3601 gatcaatgtg gatttcccac tcccggaaag ccccatgatc acgaagattt ctccttcttt
     3661 tacgtcaaaa ttcacgtcat acacaccaac cgttgcaccg gttttcttta aaatctccgt
     3721 tttcggctgg tgatcattca tcatatctaa agcggcttgt gtctttttac caaatatctt
     3781 tgttaaatgt tttacttcta cttttaccaa acaaattctc cttttttatg taaattcatt
     3841 tttctttctg aaaaaagtga ccacactatg ttaacatcat gtagtcactt tgtcaaaaat
     3901 gaaagaaatt tgcttgtcca aactgaaaaa aacttggcta aatctttgta aataaaaggt
     3961 ttagccaagt taatattttt ttaatatttc acacaatcat tctgcaagct gatgctccgg
     4021 gtaaaaaaag tttgtcatac gctgtagtgt atattcattt ccaataaaat gaacgatgtc
     4081 ccctgccgta aatttagcat aggggccagg tgaaacaagc agttcttcat tatgagaaat
     4141 tgcgataact gtggcgccag tcgcctgcca gatattcaac tcgctaattg aacggtccag
     4201 atgcattgct ttttctgata aagataattc aaacggaagt aaaggattca tcttatgtat
     4261 tcgcttcgtt tgattgacca gctgatccaa taattgagaa aaatgattca gctcatcttg
     4321 ttgcttctcc acacttgcca tgatttctgc ttttgtatct tggatggatt gtacatcttg
     4381 atattgcaat aggaaatctt ttgctttttc cttcgaagca acaaatgccc cacttccatg
     4441 ccgtacttcc atgattccaa gatctaccag cacattgata gccttgcggg tagtctcagg
     4501 agaagcattg tacgtactgg caagtgttga gcgggcatgg atcttctcac ccactttata
     4561 tcggttttca acgatacgtt cggctaaatc aacagcaatc tgctggtagc gcgggcggac
     4621 gatttttttc tttccagaca ttttctttcc tctttctttt tttactttcc ctcatcttac
     4681 tatgctctag caaaataagc aaaaaagggg agaatagcct cttgcaacga ctgatcatcg
     4741 cttgatctgt tcctttttta ctgggcaagc tgtttgacag tcatcacaat tcttaccgga
     4801 ttttaaacga gtatagacaa ttgcgcctgc acttccaaag attaacacac ttaataagaa
     4861 tgtcgccatc ctattcctct ccttctaatg acaatatagt ataaaactgg ttcttggatt
     4921 ttggctgacg gaacaaaaca taaacgagtc ctatcatcag taaaatagca agatacgtcc
     4981 ctaacgctac ctgtccaccc tccaataagt gtcccaactg ataaatcaca aaactaacta
     5041 aataagctaa accgcattga tagcctatgg cgatccaagt ccatttcttg gcattcattt
     5101 cccgatggat agccccaatt gccgcaaaac aaggcgcaca aagtaaattg aaggctaaca
     5161 atgaataagc tgctgcggga gtatatgtgt gttgtagcac ttgccagatt tctctgccat
     5221 tttcggatac ttccgcatga ccaaacaaaa taccaaatgt gccaataata ttttctttag
     5281 cgaccaatcc tgtaatcgct gcgactgttc cttgccagtt tccccaacca agcggctgaa
     5341 aaacaactgc caggattcgc ccgaaaaagg ctaagatact ttggtcttca gaaacaggtt
     5401 gagcataaaa attataagaa gagctgaacc agatcacgat actagaaaca aagataatcg
     5461 ttcctgcttt tttaacaaaa gacttgctgc ggtcataggt ttgtcttagg accgctgacc
     5521 attgaggaaa atgatatgcg ggcaattcca tgataaaagg agctgtatct ccagcaaaca
     5581 aacgtgtttt tttcaagctg attccagaga aaataattgc agtcatacca agaaaatagg
     5641 cagaaggagc tacccaagat tgatgaggaa aaaaggcccc tgctactaag gcaataatcg
     5701 gcaactttgc agaacaaggc atgaaggttg tgaccatgat cgtcaaacga cgatcttgct
     5761 cgttttcaat cgtgcgactg gccatgacgc ctggcactcc acatcctgta gcaatcagca
     5821 taggaatgaa ggattttcct gaaagaccga atttcctgaa aagtcgatcc atgacaaaag
     5881 cgatcctcgc catatatccg cagtcttcca gaaagctcaa gcataaaaac aatataatca
     5941 attgcggtag aaatcctaac actgctccca cgcctgcgat gatgccgttc aagatcagct
     6001 cctgcatcca tcccgctact tgccattcag ctaacaatct gccaacatgt tctggtaacc
     6061 atgtaccaaa caatgtgtca ttgatccaat ctgtccccat tgttcctact gtttgaatag
     6121 ccagataata gatcagccac atcacaaatg cgaagatcgg caaggctaac caacgattcg
     6181 ttgcaatctg atcgattttg tcactcatcg ataattggaa agaatcattt gacacaacac
     6241 agagtgtaca tagttgggta ataaattcat aacgttcatt gaccagaatc gtctcactat
     6301 cgtcgtccaa tagtttctct gttaactgga tcagttgctc gatctctttt tgctgagaaa
     6361 ctgctatctc gtaatcctct cttaccttct gatctcgttc aaaatatttc attgcatacc
     6421 agcgtttctt gccgctttgt tctcctagta catcttcaat ttcatgtaaa gctgcttcta
     6481 aacgtggatc atatgtacag ggaacaggaa tagaaggccg cttttttgca gactcctgaa
     6541 tcttttcgat tagtttttcg attccttgct ttttcaatac gctgattggt aaaactggta
     6601 caccaagacc ataggaaagc ttttctagat tgattttttt tccttctttt ttgatgacat
     6661 ccatcatatt cagaccaatg atcataggaa tgtctaaatc caataactgc gtagttaaat
     6721 aaagatttcg ttctaaattg gtagcatcaa taatgttgat gatcagttca ggctgttcct
     6781 gaaccaaata atctcttgca atcacttctt ctggtgtata aggagacaaa gaatagatgc
     6841 cgggtaggtc ctgaatatga atgttcggat tttttttcaa cgatccttct tttttttcta
     6901 ctgttacgcc cggccaattc cctacatatt gattcgaacc agtcaagaga ttgaacaagc
     6961 tagttttccc gctgtttgga tttccgacta acgcgatatt cattcttttt cctccctttg
     7021 tatcaagatt agttcggcct ctgactttcg taacgtcagt tcataccctc gcactgtcag
     7081 ttcgattgga tctcccagag gggctagttt tcggataact atttttacat ttcgcgtcaa
     7141 tcccatatcc attaaccgtc gcttcactgc gccttgtccg tggattgcta cgacgatccc
     7201 agtctctcct gcttttaatt gatcaagaga agtccagctt tcagaggaag cagtcttttt
     7261 attgacaaag atttgaccta gtatttcccg acttactgcc actcgatgac tttttaccag
     7321 taaaatggca ttgttgcctg ataaattgac gacgacgatt ttacttccgg caacgatccc
     7381 gatattttgc aaatggcgtt ttgttttttc ttctgtttcg attcgttcga cttgataaac
     7441 gaaattctgc tttgcctgcg ctaaggtctg catattgatt cctctcttgt gaaataaatc
     7501 atgtattaaa atcattcatt atatgttcta attttcttac gtgttacgca aataaatgag
     7561 aatcattctc acatagaata ctctcggtaa ttgagaatgt caattatact tgtgatatta
     7621 tgagcgaatc tttagtattg atagataaaa atgagaaaaa aatatttctt catagttttc
     7681 cacaattttt tctctattaa atttgctatt ttcccacacg atacttgttt tcagctcttt
     7741 tttcaaaaac acaaaactta gtattccaca gtttccacaa cacaatatgt agtgtttgtt
     7801 gtttgacttt tttactaaga gttttatact atctattata gataataaga atgtgttaga
     7861 ggaggcactc accatgaacg taaaaatctt ttctaaaaat aattgtatgc aatgtaagat
     7921 ggtcaaacgg tttttaacag aaaatcaaat tgcttttgaa gaagtcaata tcgatgaaca
     7981 gcctgaagca gtagactggt tgaaagcaca aggattccaa agtgttcctg tcattacttc
     8041 tgatgcagaa acagttatcg gattccgtcc tgatcagttg cgtaaacttg ccagctaaca
     8101 tgactaaaag aatcaaaacg tgatacatgg atttgaaggg cttgagacag caccagtttt
     8161 tgtcgcaaac ttccaaatcc ttttttaaag cttaaaaaca atgcaatgat ttgcaatcaa
     8221 gcatcatcaa atacgaaatg aaggttgggc gtacgtatga gtcttaaaaa tttacaagat
     8281 gtcagttatt tcaagctgaa taatgaaatc aatcggccag tcaatggtca aatccctttg
     8341 aataaggata aagaagcttt agttgccttt tttgaggaaa atgtcaaacc aaatacgatg
     8401 acttttccat ctattatgga aaaaatcaat tacttgatcg atcaagaata tatagaagca
     8461 gaattcattc aattgtattc accatcattt attgaaaagc tatatcaatt tttggacgag
     8521 caacattttt ctttcaaatc ttttatggct gcttacaaat tttattctca atatgcgttg
     8581 aaaaccaacg acggttccgc ttatctggaa acttatgaag atcgagtagc cttcaatgcg
     8641 ctttactttg cgaacgggga tgaagaatta gcacttgctc ttgcagacga aatgatccat
     8701 caacgatatc agccagctac accttctttc ttgaatgctg gacgtaaacg tcggggcgaa
     8761 ttggtgtctt gtttcttgac tcaagtcact gacgatatga actctatcgg gcgctcaatc
     8821 aactctgctt tgcaattgtc ccgtattggt ggcggcgtag ggattacttt atcaaatctt
     8881 cgtgaagccg gcgctcctat caaaggatat gagggtgctg caagtggtgt cgttccagtc
     8941 atgaaattat tcgaagatag tttcagctat tctaatcaat taggtcagcg tcaaggagct
     9001 ggcgtggttt atttgaacgt tttccatcca gacattattg ctttcctttc agcaaaaaaa
     9061 gaaaatgcag atgaaaagat tcgcgtaaaa actctttctc ttggcgtgat cgtacctgat
     9121 aaattttatg aattgacacg taaaaacgaa gatatgtatt tatttagtcc atatagtgtc
     9181 gaaaaagaat atggtgtccc attctcttat gtaaatatta cagctgagta tgatcatcta
     9241 gttgcaaatc caaacattcg caaacaaaaa atcaaagcgc gtgatcttga aaatgaaatc
     9301 tcaaaattac aacaagaatc tggctatcct tacgtaatca atattgatac agcgaaccgc
     9361 gagaatccaa tcgatggcaa gatcatcatg agtaatttat gttcagagat tttacaagtt
     9421 caaacgcctt ctgtgattaa cggcaaacag gaatatgaag tattaggaac agatatctca
     9481 tgtaacttag gctcgacaaa tatcgtgaat ttgatgcaaa gccctaactt tggtcaatct
     9541 gtgcgtacga tgactcgtgc attgacattt attacagatg catctgatat cgatgtcgta
     9601 ccaccgatcc aaaacggaaa taagctgaat catacgattg gattaggtgc catgggctta
     9661 cacacttatc ttgcaaaaga acaaatggaa tatggctcag aggattcatt agactttaca
     9721 aatatttact tcatgctgtt gaattattgg acacttgttg aaagcaacaa tatcgctcgt
     9781 gaaagaaaac aagttttcca taattttgaa aaatcagctt atgctgacgg cacttatttc
     9841 gaaaaatacg taactggaga attccagcca aaatcagaaa aagtcaaagc attgtttgaa
     9901 ggcattttta tcccaactgc tgaagattgg aatgctttga aacaagcagt aatgaaagat
     9961 ggactgtatc atcaaaatcg cttggcagta gcaccaaatg gctcaatttc atatatcaac
    10021 gatacgagtg caagtattca tcctatcact cgcatgatcg aagaacgcca agagaagaaa
    10081 atcggtaaaa tttattaccc agcgccttat ctatccaatg agacgattcc gtattacact
    10141 tctgcttatg atatggacat gcgtaaagta atcgatgttt atgcaacggc acaacaacac
    10201 gtcgatcaag gcatgagttt gactttattc atgcgttctg aaatcccaga aggcatttat
    10261 gaatggaaga caacaacgaa gcaaacgaca cgtgatttga atattttaag acattacgct
    10321 ttccacaaag gaatcaaatc catttattac gtacgtacct ttactgatga tgcagaagaa
    10381 atcggaagca atcaatgtga aagctgcgtg atctaatatc atagatagat tcgcttattc
    10441 atattttaat taaaggagca ttctcatgtc agaaacatat tatgaagcaa taaactggaa
    10501 tgaaattgaa gatatcattg ataaatccac ttgggagaag ctgacagagc aattttggct
    10561 agatacacgt atcccacttt caaatgacct agatgattgg cgtacattgt ctcaattgga
    10621 aaaagataca gtaggacatg tatttggcgg tttgacactg ctagatactg tccaatctga
    10681 aagtggcatg gatcagttgc gtaaagatgt ccgcactccc catgaagaag ccgttttgaa
    10741 caatattcaa ttcatggaat ccgttcatgc caaaagttat tcttctattt ttagtacact
    10801 gaatacgaaa aaagaaatcg aagaaatttt tgactggaca aatacgaatc cttatctgca
    10861 aaaaaaagct gagcgtatca atgaaatcta caaacacggt acaccgctag aaaagaaaat
    10921 tgccagcgtc tttttagaaa cattcttgtt ctattcaggt ttttatactc ctctttatta
    10981 tttaggaaac aacaaattgg ctaacgtagc agagatcatc aaactaatca tccgagatga
    11041 atctgtacat ggaacctaca tcggttacaa attccaatta ggattcaacg agttacctga
    11101 agcagaacaa gaaacgttaa aagactggat gtacaatctt ctttatgagc tttacgaaaa
    11161 cgaagaacgt tatacagaag aattatacga tccaatcggc tggacagaag aagtcaagac
    11221 attcctacgc tataatgcca acaaagcatt gatgaaccta gggatggatc cactctttcc
    11281 agatactgcc aatgatgtca acccaatcgt aatgaacggg atttcaacag gcacaagcaa
    11341 ccatgacttc ttctcacaag tcggaaacgg ctatttgtta ggtcatgtag aagcgatgaa
    11401 agacgacgat tatttgattg gattggaata aggatttatt ttaattcaaa aatttttcga
    11461 aaaataaaaa gagtttagcg tacagatatt ttaaatgtac actgaactct tttttatgct
    11521 tattcacttg tttcttccag cacttttgga ctgtctaact tttccgaaac atgttccatt
    11581 cttctcaata aatagatttt ccggatattt aatattatcg tcttaatcac tgcatagaca
    11641 ggtatgcaaa tcagcatgcc taatattcct gcgacacttc ctgctccaat caataccaag
    11701 atgatcgtca aaggatggat attcattgat ttcccaaata acaacggctt gatcaaattt
    11761 ccatctaatt gttggatcac taaaatcgac aacgccatat acaaagcttg aaatggagag
    11821 ataaacaaac cgacaatgat tgctggtacc gctccaataa aagggccgac atacgggata
    11881 atattcgtga ttccgcaaat gaccgcaagc aacaagctat aaggctgatc gaatattctc
    11941 attgccaaaa agctcattac accaataatc aaagcatcta agatcgtact gctgatatag
    12001 gcagataatg tttcgtttaa ttcttttacc gtttggcgta actctttacg aatcgctttc
    12061 ggaaagaagt gagacaacgc atcaataaat ttgtgcccat ccttgaacat aaatagcaaa
    12121 ataaatggaa cggtaaataa caaaataaaa aattgcatca taaatgaaat gatttttgag
    12181 acacttgcag ataaactgac taatatgata ttgaacaaat tactaagaga taaatttgct
    12241 gatgctaatt gttcttccaa attgaaattt ttaaactctt cccgctgcgc caattcattt
    12301 aaccatttgc ttgtttcatc tgcatacatt ggcaagctct gggtcaattg aattgtctgt
    12361 tccattaact gaggcactac attcatgaca gttaaaacaa ctaaaatgat tacgaccaaa
    12421 aacgtcaata aaaaaccgaa cactctcggg atccgatgct tttcgagaaa aacaacgatt
    12481 ggatcgaaca tataatagat aaaaccagca acaagcaatg gtaaaaaaat tgccgaaagc
    12541 attttcaata ttggactaaa aatattcggc atttgtaaaa taaagtacac gccgatgatc
    12601 gtgagtacta gctccactgt ccagaaaaat aattttgatt gtttaaaacg tgattgcata
    12661 catctcctcc aaggtccttt gatacttcta ttctatcatt taacaaagag ttacgcgctg
    12721 agattttcat ttgcttaaaa aaaacaaaaa aaataaacat attttaatga gtagacgagt
    12781 acttaaacaa aaacacggtt tggagtagtg acaaaaatta tactgcagtc cctttttcca
    12841 aataaacggt gttcaaaagc ttgcatcttc gtaataagcc cagccaaacg aaaaatataa
    12901 ggaactattt ttatttggct gggcttatta cttgatgtag gacatctatt ttacaacctc
    12961 agatcattta ttgcgcaata ctgactaaat gcaactttgt gatatttttg tgtacggaca
    13021 actcctcgat cacatcggca taagtgagcc cttttggaag atcaatcgta tagatatttt
    13081 tgtacactcg gtagtcatca acgaatttta cgtcaaaatt cacatcttcg attacgatat
    13141 ttttctcttc aaaataatcg gtaagaaaat ctttggtttc ttttctatgg ataaattgga
    13201 tttctaactt tttagtcgta ggtacatgga tcacgcgttt cactactgtg agtgcaatag
    13261 caatcccgat aaaactgatg atcgcaatgg aatagtaacc catgccgatg gcgatcccta
    13321 atccagcaat tgcccataaa gaagcggcag tcgtaagtcc cgtcaccgat tgtttcgtga
    13381 cgatgatcgt tcccgcgcct aagaaaccga caccactcac cacttgagca atcagccttg
    13441 cttcatctga acgaatcgtt ccagcaagct gtggatactc taaagcatct cttaatgcac
    13501 cactagcgat ctcaacttgg atcaatgcaa tgatacatgc tcccatacaa actaaaatat
    13561 gcgtacgcat acctgctgga cgatttttat attgtcgttc aaaaccgatt gctccgccaa
    13621 atagcatagc gatccctaaa cgtaaaataa tctctggaat tgtcaatacc atatcattca
    13681 tctaaacacc ctccagtcca atatatcatg tctgaaagga gcagacaaaa aaagtgcaat
    13741 ttttacctct tacgaaaaaa ggactgtgac aaaatttttg tcatagtcct ttttatgaat
    13801 aaacggtgtt caatcagctg accctcggta ttactcaaca aacggcaaaa tatggggagc
    13861 tatttttcct ttgtcttctc taatactcag gtcaaaacgc tgatttcaca acctctttag
    13921 cctactattg aaaattacaa cttacttgct gcttcttcat cgatgatcac aacaacattg
    13981 tcgtgatttt gcaatacact tgctggcaaa tgattcgtta caggtccttc aatcatccct
    14041 ttgattgcat cagctttgct ttcgccaaat gccatcaaga cgatttcttt acttttcata
    14101 attgaaccga ttcccattga aacagctttt gttggtacat cttctgcttt atcgaagaat
    14161 cgtttgtttg cattgattgt tgattctgtt aagtcaacta ctgaagtcgt tccgtcaaat
    14221 gaagcaccag gttcattgaa accgatatgt ccattttgcc cgattcctaa gatttggata
    14281 tcgattggat gtgcatcgat gatttgatca tactttttgc atgctgcttc cagatcttct
    14341 gcttttccat ctggtacaaa cgtttctttg aatggttttt tatcaaataa ttggacatcc
    14401 atgaaatgac ggtagctttg ttcatctgaa ccgcctagtc caacgtactc atctaagttt
    14461 acagaagtca tttcactgaa atccaaatcg cttgaagtca tttctttata taaagtaact
    14521 ggtgtgcttc ctgttgccaa tcctaatact tttgcacctt tgttcatacc ttctttgatg
    14581 atttcaaatg ctttttttcc gccttcttca gcgtttttta cacgaatgat ttccatagtg
    14641 attgctcctt tatattttgg tatagcccaa ttatagcatt ctttttttct ttttacaata
    14701 attagtatag accaaattgc atttttttca ttttcttgac aataaatagg aatccgtgtt
    14761 aggtttcata agatggttca atcaaacaat ccatgttgca tgaaaaccaa gcaagtgatt
    14821 cactgtggac gctttatgtc tgcagttttt ttatgaaaaa ggagttatta tgagtatact
    14881 gacattaaac aacattaccc agcaatttgg cgacaaaatc ctctatgaag gtgtcgatct
    14941 gcaattaaat gctggcgaac atcttgggct gattggacaa aacggagccg gtaaaagtac
    15001 attgattaaa atcatcactg gtgagatctt accagatgac ggacagatcc attggcaaaa
    15061 aaatattcac aaaggttacc tcgatcaata tgtggaagtc gatgaaacat taacaatcga
    15121 agaatttcta aaaactgcgt acgcaaaaga atacgaaaag gaagaaaaaa ttgcttttct
    15181 ttaccaaaca tatagcgaga ccttcgatga ttccttgctg gaaaaagctg ggaaactcca
    15241 aacggaatta gaccaaggag tgttttatca aatcgacacc ttagttgctg agatgagcag
    15301 cgggttgggg atcgatgtct taggtttaga ttcactgttg aaaaatctaa gtggtggaca
    15361 acgttcaaag gtgattttag caaaactact tttagaaaac ccagatgttc tgatcttaga
    15421 tgaaccaacc aatcacttag atgatcagca tatccaatgg ctgacgcagt ttcttcagga
    15481 ttttgacggt gcgtatatcg tgatttccca tgaccaagaa tttcttgatc agatcaccac
    15541 ccatatcgca gacatcgagt ttggaaagat tactaagtat actggccatc taaaacaagc
    15601 attgaaacaa aaggaacaaa atcgcgaaag ctatttgcgc caatatcatg ctcaacaaaa
    15661 acaaatcgaa aagaccgaag cttatattcg aaaatacaaa gccggttccc gatcaacgat
    15721 ggcaaaaagc cgacaaaaac aattagataa aatcgaacgg ctgacgcctc cagcttcagc
    15781 aagtaaagct gtctttgatt ttccattctc gcctattgtc acgacattag cagtggaaac
    15841 aactgattta gtcatcggat atgatcgacc gctacttgca cccatcaatt tgaccatccg
    15901 ctttggtgaa aatattgcca ttcgaggctt caacgggatt ggaaaatcta ctttattaaa
    15961 aacactgatc ggtgagattg aaaaaataag tggcgatttc cacttcccag ataacacaaa
    16021 aatcaattac ttttcacaag atctgtactg ggaaaatcca ttagaaacac cactacaata
    16081 tttaagcagt caatttccaa aagcgactat caaagaatta cgtcgccaac tagctaaagc
    16141 agggttagtt aatcaattag caagtgaacc tctcactaca ttaagtggtg gggaacaaac
    16201 taaggtgaaa cttgcacagt tgacaatgaa ccaaggtaat ttactgattc tcgatgaacc
    16261 gacgaaccat atcgatcaag aaacgaaaga aagcttacaa gacgggatac agaaatttcc
    16321 aggaacagta atcatcgtct ctcatgaaca agaattttat caagatcttg tgcaacgagt
    16381 cattgagatt gaaccaaaat aaacgtttga ttgaatagtt gaaaaaaagg agctgtgaca
    16441 aaagttttgt cacaactcct tcttctgaat aaatggtggc caattagctg accttcggta
    16501 ttagctcaaa aaacggcaaa atatgaggag ctatttttat ttggctattc ttattacttg
    16561 atgcagaaca gcttttcaca acctcttttc gtctattttt tattttcgag atttctcttt
    16621 cctttaaaaa caactgtttg aaagaagaac gcacatcctt gaaaaacaag cccgctaacc
    16681 gttacaccta accagccata ctgctgccac attgtcgtcc ctagcaatga accagccgca
    16741 cctccaataa agtacataaa cataaataca
//
LOCUS       DAFLWC010000065        16714 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.066, whole genome shotgun sequence.
ACCESSION   DAFLWC010000065 DAFLWC010000000
VERSION     DAFLWC010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16714
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.066"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(251..1462)
                     /locus_tag="L1V17_002010"
     CDS             complement(251..1462)
                     /locus_tag="L1V17_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1236763.1"
                     /translation="MSEVTGYLEQVDNETYRLRAVLGYKPDGSAKRKSKTIKASSKRA
                     AYKELNIWLEQFEGMTDDSLDLFNITFGEFYRKIWLSEAEKNLEPKSYHNYKRMIENR
                     FLDKFDFIPLIDIKPYMIKKIVVNAQRINTKDPGRNSDKPLSRNTKLRMLYAVNNLFL
                     MAKNEYGAIKENPVENVKIPKEKGVKKNIEEPYSEEEIHAMLKAAFEESIEIKTLIVL
                     AFITGARQGEIAALEEKDIDFDKQEIRFHQRISEVDGKSDIRLLPGLKNDDDEKIVTG
                     PAYLFDMLDELIKENKKIRWKLNIKKLKHYFIFDTKQDGTLPRGSYLYKKFKRFTKRH
                     NLRHIRFHDIRHTSATYLLSDPNMTPKELQKRLGHRDFNTTMNVYGHVLRKEKDTATT
                     AFENLLKKDIK"
     gene            complement(1581..2216)
                     /locus_tag="L1V17_002011"
     CDS             complement(1581..2216)
                     /locus_tag="L1V17_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HBN1236764.1"
                     /translation="MAKKVMGQDGKMYKVKKPFYKRVWFWVLIVLLFFGIGGALSGGE
                     NKDSATATSTSTNKETTKETTTKEEKTYKIGDDVAVGKMEYKVNSVEVVKQVGPSVLP
                     TNAKDTFLVVDLSVKNAGDKAVTVDSSFFKLKADGKTFEADSAASMSANQDENGNITN
                     SFFMESLNPDMQQTGKIVFDISEAQANAKNNVLQAQTGYFGTETVSIALHN"
     gene            complement(2352..3005)
                     /locus_tag="L1V17_002012"
     CDS             complement(2352..3005)
                     /locus_tag="L1V17_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236765.1"
                     /translation="MKKVSVMLLLSTALLLSACSNNKKAESTDATSNQETKISKTKET
                     TETSSSTSKSTSKTDSSSTVTSSNQVTAEPSPTVISSSQSTIQTAPQEETYEQMKQRT
                     LQSTPADRANWSNKEWEAFGVALYENGLTTDDAGNIISQDQKEQQAASQQNPEDQQTS
                     AQQDADTLSLTDFVNKYGMSPVAWKVQNGMSEEEALRTTQQKTSGEVQLGFFKYGIQ"
     gene            complement(3108..3314)
                     /locus_tag="L1V17_002013"
     CDS             complement(3108..3314)
                     /locus_tag="L1V17_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HBN1236766.1"
                     /translation="MPSYVVLQVVLKEKFIGKGSQNLSELENTINRQCSKGYRLHTIS
                     TTNGGSKGFGGGDRIQATLVFESL"
     gene            complement(3390..4136)
                     /locus_tag="L1V17_002014"
     CDS             complement(3390..4136)
                     /locus_tag="L1V17_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004564412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1236767.1"
                     /translation="MKQTTQQRLNQLMSERNLKQVDILNMSLPLQKETGIKMSKSHLS
                     QYVNGKSSPDQHKLYLLAKTLNVSEAWLLGYDVPKEDKKNNIPSIETIYNQLEKPRQT
                     KVYNFAEQQLEEQNRGNVVHFPKKEKLPTIKNSASAANPTELVYGDTVVEEEEFERVP
                     NNADFAVPIIGDSMEPVIRNGQFVFVKEQPDVEDGEIAIVEIDGDGVTCKEVYKDYES
                     QTIILRSINELYEDRVVSPEQIRIIGKVVF"
     gene            4296..4520
                     /locus_tag="L1V17_002015"
     CDS             4296..4520
                     /locus_tag="L1V17_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF739 family protein"
                     /protein_id="HBN1236768.1"
                     /translation="MSFDYSKLSGRIVEKYGTQYNFSIALGLSERSLSLKLNNRVPWK
                     STELQKAIELLDIPKEEIGEYFFNLEVQNV"
     gene            4544..5305
                     /locus_tag="L1V17_002016"
     CDS             4544..5305
                     /locus_tag="L1V17_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HBN1236769.1"
                     /translation="MNTQKFENNLFELEVKTENGESLFNAETVARSLGFVETKNGKEY
                     VRWRTVNGYLKKYLSQEVAKNDFISEPMVYKLAFKANNVLAEKFQDWLATEVLPQIRK
                     HGMYATDELLNNPDLLIEVATKLKEERTLRLIAEQRVNELQPKADYYDRILNNKGLVT
                     VSTIAKNYGMSAVSFNKLLHELGIQFNQSGTWLLYSKFQDKGYTHIEPFDYEDKNGNR
                     QVKTRMKWTQKGHIFLYETLKKNNYLPMIEREQTA"
     gene            5317..5574
                     /locus_tag="L1V17_002017"
     CDS             5317..5574
                     /locus_tag="L1V17_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236770.1"
                     /translation="MNEEMSQTIKVQKMIDDLTHAIDSQADKIIKELQGQKVWDAKML
                     FKTIKFEMNPTKRKLADVLEEKLASAINEQELLFETDTFNS"
     gene            5666..5917
                     /locus_tag="L1V17_002018"
     CDS             5666..5917
                     /locus_tag="L1V17_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1236771.1"
                     /translation="MEQLALVNLSDLKASLAESEIANEVWDTKQAAEYLKTTTRTLTK
                     DAESGKIPAAKVGREWRFSSIALYQYLKGGKTWVNSTEH"
     gene            5893..6066
                     /locus_tag="L1V17_002019"
     CDS             5893..6066
                     /locus_tag="L1V17_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236772.1"
                     /translation="MGKFNRALVFSAPLIVYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEYRAKKPTEGAD"
     gene            complement(6180..6587)
                     /locus_tag="L1V17_002020"
     CDS             complement(6180..6587)
                     /locus_tag="L1V17_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236773.1"
                     /translation="MSFDNTITISIILALVALISPSITAVINNKHVESMKDKEIELQK
                     HDSKTQTIQTTFSTFLNNVGICIGSNTDKNISAVKASGYAVLPYIQNEDIEVMKIFLS
                     RFGYGNTDAEQKSLETYLIDKVLPILNKSLEKL"
     gene            6748..6972
                     /locus_tag="L1V17_002021"
     CDS             6748..6972
                     /locus_tag="L1V17_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236774.1"
                     /translation="MISVKGLGDEIFEAMMSKAQQDIKEKIISAAAQGQTSCTVRSRG
                     TTPSFLLALEDEGILNIKRRDGSVRLFWQF"
     gene            6982..7176
                     /locus_tag="L1V17_002022"
     CDS             6982..7176
                     /locus_tag="L1V17_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236775.1"
                     /translation="MKDFDSLGARQQPPNEASPVGVDWQENPLYPGDTCYLTEEGYVP
                     VDAILEYVQQHYPKIELGGI"
     gene            7179..8201
                     /locus_tag="L1V17_002023"
     CDS             7179..8201
                     /locus_tag="L1V17_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HBN1236776.1"
                     /translation="MANDLTQTTQRSLDEQVISNLGRLQEQGLEMPPGYSPQNALKSA
                     FFELTNNTGGNLLQMAANNQEMKTSISNALLDMVIQGLSPAKKQCYFIKYGNKVQLMR
                     SYFGTMAVLDRVTGGADITPVVVRQGDEFEVAMDGPNMVVKKHETKFENLDNEIIAAY
                     VVIKLTNGKETTTVMTKKQIDQSWAKSKMKDSGPQKEFPEEMAKRTVINRAAKTLINT
                     SNDNDLLVQAAKDTLENEFDNDRKDITPQTEKVATLEQKFFSNKKITEPIQKEPDPIV
                     IPDDIQNEVTRVADVPAHPEIEQAHLIENEDINPIQEELIDIPDFGREEGVEDVSEFE
                     DDEYPF"
     gene            8164..8979
                     /locus_tag="L1V17_002024"
     CDS             8164..8979
                     /locus_tag="L1V17_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HBN1236777.1"
                     /translation="MSQNLKTTSTLSDENYYSNEADWQYMSTSQYKSFLKCEAAALAK
                     LKGDWAPTSDPKALLVGNYVHSYFESKEVHEAFKEENKSKMFSSRKPYGLLKDFQIAE
                     QMIERLKQEEAFMNIYQGEKETIVTGELFGTTWKGKIDCLNVEDEYFVDIKTTKDMHE
                     RKWNENYGSRETFIVNFGYVLQMAIYQELLLQQYGKMFMPIIAAVSKQTPSEAKLITI
                     DQDKMSYELIMLKENIERIVKVKNGEERPIPCGTCEYCRGNLSITGFTSMDDL"
     gene            8997..9779
                     /locus_tag="L1V17_002025"
     CDS             8997..9779
                     /locus_tag="L1V17_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236778.1"
                     /translation="MNLGYIKLYRKVTSSFVWTNSDMFKLWILCLMKASHEDRKFLFN
                     GQEVRLTSGQFVTGAHAIAKEYNEGVPSDKAIAWRTLWRWLKKFENEELLTIQSNARY
                     SVITIINWSDYQSSDKPVTSDGQSSDKPVTTNKNDKNDKNDKNNNPRNSRKTREYADD
                     DPNKKLAILLLKLIRKNRSLKEPDLNKWANTIRLTIEADKRTGKEVQDMIVWATNHDF
                     WSTVISSPTSLRKNFDTMVGQKNKRKQQNISNDELPETGEDW"
     gene            9779..10627
                     /locus_tag="L1V17_002026"
     CDS             9779..10627
                     /locus_tag="L1V17_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBN1236779.1"
                     /translation="MNKKLSAMAAPYGGLKTADHNCPKCGDPLYIWKTKNKDGTDRCG
                     PTCINKICGYREMVTKNQKEAIQKANEAMKKDAINRMLNSSMITDDAIWTFDFDGYKV
                     VDQETAQIKAMAQEWAKKIVNGSTIHAVITGRTGAGKTHLGAAVIKEVMRASNYKIAC
                     SFISYRELLEQLKFAMNDPEARKAVTGSLMAEIKKSDFVVIDDLGAELGRMEENNQAT
                     PYDVDVLTSLTEARLNKATIFTTNLSSKQLKHAYGERVFSRVMNGTKGNIAVFKTTTD
                     KRRNPV"
     gene            10624..10866
                     /locus_tag="L1V17_002027"
     CDS             10624..10866
                     /locus_tag="L1V17_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236780.1"
                     /translation="MTFVVKKMCYLDSRGRGEASVEFAKHHTTKEEADLVASVCGGEV
                     VEVIKPKRRFSKPKTKPVKKECCCPKSNQAWMRGAK"
     gene            11009..11377
                     /locus_tag="L1V17_002028"
     CDS             11009..11377
                     /locus_tag="L1V17_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HBN1236781.1"
                     /translation="MATRSKYGNKKHEVDGITFDSITEAEYYDLALWQAQANGWKVKL
                     QERFELMPKFELEGKKYRKIEYIPDFTFYKSGKLVKVVDVKGMQTKDFKIKAKLFCHQ
                     YQVPLILAKKYRNTFKEERF"
     gene            11392..11553
                     /locus_tag="L1V17_002029"
     CDS             11392..11553
                     /locus_tag="L1V17_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBN1236782.1"
                     /translation="MTTEEVIQMRIRSLRREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            11550..11876
                     /locus_tag="L1V17_002030"
     CDS             11550..11876
                     /locus_tag="L1V17_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236783.1"
                     /translation="MSVDKEAAWRKLMLLIQDENWQEDEAVVAEVQRLGKIANGRIRK
                     KPDKRKQRKGKIVVVLHEGKILMQGTASELSAETGYTRGTIRTYAWRNHTDRKGHEYK
                     YLEEEK"
     gene            11873..12688
                     /locus_tag="L1V17_002031"
     CDS             11873..12688
                     /locus_tag="L1V17_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HBN1236784.1"
                     /translation="MNENKLIKLGVAGAVIVGIGVIGGFKFFEKIDNGYVGVRYSMNG
                     GIKDEALTQGVKFVGIDKVIQYPIRLQTIQSKNISVSTSDGKKTTIDIKYDYKVDSTK
                     AAKMYKEFGNITSEDIESGWLKSKLQKVAREVYAKYSLLDVLSGDSSKVEAEVLTNFA
                     KSVESKGFEVEDVTLGVPDVDKETQKSIDAIIRAGQENEKAKLDAETAKTQADSEAYK
                     KTKAAEAEAESNRKVAESVTDNLIRYEEAQARKKHGWVTVNGADTVVTDEAGK"
     gene            12827..13138
                     /locus_tag="L1V17_002032"
     CDS             12827..13138
                     /locus_tag="L1V17_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBN1236785.1"
                     /translation="MDELITKVEQWAKDKGLDQADPKAQFLKVAEEFGEIASAMARSN
                     DELFKDSVGDVIVTLIILSMQKGTNVQECLEMAYNEIKGRTGKMVDGVFVKSSDLEGS
                     K"
     gene            13162..13380
                     /locus_tag="L1V17_002033"
     CDS             13162..13380
                     /locus_tag="L1V17_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236786.1"
                     /translation="MDLYDIESGATLSVESDHLIINFGGKRQIILWVVDDVLFPEIVH
                     DFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            13377..13793
                     /locus_tag="L1V17_002034"
     CDS             13377..13793
                     /locus_tag="L1V17_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HBN1236787.1"
                     /translation="MIPKFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVDIFEGDIVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVIGNIYENSELLEVE"
     gene            13790..14128
                     /locus_tag="L1V17_002035"
     CDS             13790..14128
                     /locus_tag="L1V17_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236788.1"
                     /translation="MIILATDYIDSLKDENGNVPALLNCGIKSKNRIILLRISADLAK
                     YLYLSKTAVYYTAATRYQYKGKTISQDYYDRLISPDMYGNSESAIKLFGAIEIYADDF
                     PNLWLKEEAE"
     gene            14125..14355
                     /locus_tag="L1V17_002036"
     CDS             14125..14355
                     /locus_tag="L1V17_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236789.1"
                     /translation="MKYEIPLSEADVQSIINGREVNKKLPDGTELVIRQSYLKDMAAP
                     VLIDRFNVTDSVVENHLKEFRSSINDTFRLGS"
     gene            14362..14565
                     /locus_tag="L1V17_002037"
     CDS             14362..14565
                     /locus_tag="L1V17_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HBN1236790.1"
                     /translation="MNTRHRRVAKLRKQELNVLKTKFEKEYGISAEETYKVASQCVAD
                     ASDAIRKFGISILSDDRKWEEKE"
     gene            14562..14858
                     /locus_tag="L1V17_002038"
     CDS             14562..14858
                     /locus_tag="L1V17_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236791.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKPKVKVGDMVRCEA
                     EEFIYPFRGYVEHVYNHSAIIRIENTMECDKWTAKSKENLAVVRLVDMELINDK"
     gene            14935..15348
                     /locus_tag="L1V17_002039"
     CDS             14935..15348
                     /locus_tag="L1V17_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBN1236792.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDALIQMMDIEAERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            15361..15747
                     /locus_tag="L1V17_002040"
     CDS             15361..15747
                     /locus_tag="L1V17_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236793.1"
                     /translation="MWKDYVSLKELKKDLVFKRIVEWSESELILEDGTKMEVVCSESD
                     CCAWAEGEFKNVKLDAVITDIKIFDKGNRLYNGDGHTSYAEVVVYHNRNEIAKAECTA
                     NDGNGGYYYSVCALKVKDKLCIVTDA"
     gene            16298..16525
                     /locus_tag="L1V17_002041"
     CDS             16298..16525
                     /locus_tag="L1V17_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236794.1"
                     /translation="MRTYWYVSLNNKYPKPMKGQHRRVVMSVQMKAKYSIVEMLREAT
                     PKEIDQYKLVLIGIGWFKDEHIQTNMKRWLR"
BASE COUNT         5664 a         2726 c         3485 g         4839 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtt
      121 cgttatttaa tggtatttta aatgaagata agcgaattta cagcattttt aaatgcttat
      181 ataccgcaaa ttatcccaag tttttgtata tcctacccga gtttataccc gaaaatataa
      241 ttttttagtg ttattttata tcttttttta ataggttttc aaacgctgta gttgctgtat
      301 ctttttcttt gcgtaagaca tggccataaa cattcattgt agtattaaaa tctcggtgtc
      361 ccaatcgttt ttgaagctct tttggagtca tattaggatc gctaagcaaa taggtagctg
      421 atgtatgtct aatgtcgtga aaacgaatgt gacgcaaatt gtgacgtttg gtgaatcgtt
      481 tgaacttctt atacagataa cttccacgtg gcaaagttcc atcttgtttt gtatcaaata
      541 taaaatagtg ttttaatttc tttatattta atttccaacg aatcttttta ttctctttga
      601 ttaattcatc taacatatca aatagataag caggaccggt tactattttt tcatcatcat
      661 catttttcaa acctggcagc aaccgaatat ctgattttcc atccacttct gaaatccgct
      721 gatgaaatct tatttcttgt ttgtcaaagt caatatcttt ttcttctaaa gctgcaattt
      781 ctccttgtct tgctcctgta ataaatgcta gaacaattaa agttttaatt tctatgcttt
      841 cctcaaatgc tgcttttagc attgcatgaa tttcttcttc cgaataaggt tcttcgatat
      901 tcttttttac gcctttttct tttggtattt ttacattttc cacaggattt tctttaattg
      961 ctccgtactc atttttagcc atcaaaaata agttgttaac ggcgtataac atacgaagct
     1021 ttgtatttct tgataaaggt ttatcagagt ttctcccagg atcttttgta ttgattcttt
     1081 gagcattaac aacaattttc tttatcatgt atggtttgat atcgattaga gggataaaat
     1141 caaatttatc aagaaatcta ttctcgatca ttcgcttata gttatgataa gactttggct
     1201 ctaaattttt ttcggcctct gaaagccata tttttctata aaattcacca aaagttatat
     1261 tgaacaaatc caacgaatca tcggtcattc cttcgaattg ctctaaccag atgttcaatt
     1321 ctttatatgc cgctctttta ctacttgctt ttatagtttt gctttttctt tttgccgagc
     1381 catcaggttt gtatcctaat acagctctta gtctatatgt ttcgttgtct acttgttcta
     1441 agtatcctgt tacttctgac ataattgaat cagctctctt tctctgatac aataggtact
     1501 ataaagaagc ctatcgtata ggtttgtttc tttcttagaa cacgctcgct ttggtcggtg
     1561 gggcgtgttt tttatactaa ttagttgtga agagcaattg aaactgtctc tgttccaaag
     1621 taacctgttt gtgcttgcaa tacattattt tttgcatttg cttgggcttc agagatatca
     1681 aaaactattt taccagtttg ttgcatatca ggatttaagc tttccataaa gaaagagtta
     1741 gtgatattac cattttcatc ttgatttgcc gacatagatg cagccgaatc agcttcgaaa
     1801 gtttttccat ctgcttttaa tttgaagaat gagctatcaa cagtcacagc cttatcacct
     1861 gcatttttta cagataagtc aactactaag aaagtgtctt ttgcgttagt aggaagtaca
     1921 gatgggccaa cttgttttac tacttcaacg gagtttactt tgtattccat tttccctaca
     1981 gcaacgtcat caccgatttt ataagtcttt tcttcttttg ttgtagtttc ttttgtagtt
     2041 tctttattag tacttgttga tgttgcagta gctgaatctt tgttttcacc gccacttaga
     2101 gcaccaccaa taccaaaaaa caaaagtact attaataccc aaaaccatac ccgtttataa
     2161 aacggttttt taaccttata cattttccca tcttgaccca taactttttt tgccatttaa
     2221 atattcctca tttcttgtta taatatattt gtgatctcag aaatgaggta tgagtccgtg
     2281 ttgcagcacg ggctttttta tttataactt ttttagagat tataggcaaa atagtagggc
     2341 ataaaaatat attattgaat tccgtattta aaaaatccta attgaacttc accggaagtc
     2401 ttttgctgtg ttgtacgcaa tgcttcttct tcagacattc cattctgtac tttccatgca
     2461 acaggcgaca tcccgtattt gttaacaaaa tcagtaagtg ataaagtgtc agcgtcttgc
     2521 tgagcgcttg tttgttggtc ttctggattt tgttgagatg ctgcttgttg ttctttctga
     2581 tcttgactga taatattgcc agcatcatct gtagtcaatc cattttcata aagggccacg
     2641 ccgaaagctt cccactcttt gttggaccaa tttgcacgat cagctggagt tgactgtaaa
     2701 gtgcgttgtt tcatctgttc atatgtttct tcttgaggtg cggtttggat tgtactctga
     2761 ctggagctta taactgttgg gctaggttcc gccgtaactt ggttggagct tgtaactgtt
     2821 gaactagaat ctgttttaga tgtagatttg ctagtagatg aactggtttc agttgtttct
     2881 tttgttttac ttatttttgt ttcttggtta gaagtggcat ctgttgattc agctttttta
     2941 ttatttgaac aagctgaaag tagcagagca gtacttaaca acaacataac gctaactttt
     3001 ttcattttat actcctcttt tctttgatac aataagttgt aaagaagcct actataggtt
     3061 taacatccca cgtccacaaa ctttggtcgg tgggcgtgtt tttttgttta tagactttcg
     3121 aaaactaaag tagcttggat tctatcgcca ccaccgaaac ctttactacc accgtttgta
     3181 gtggaaatag tgtgtaatcg ataaccttta gaacactgtc tatttatagt gttttcaagt
     3241 tctgataggt tttgcgaccc ttttcctata aacttttctt ttaatacaac ttgcaataca
     3301 acgtaacttg gcatattctt ttccttcttt ctactatgat aataaatact aacccctagc
     3361 cggagcgcca actacgactg gggtattttt tagaatacga ctttcccgat tattctaatc
     3421 tgttccggtg agacgactct atcttcatat aattcgttta tagagcgtag aataatcgtt
     3481 tgactctcat aatccttata tacttcttta cacgtcacac cgtcaccatc tatttcaacg
     3541 atagcaatct caccgtcttc cacgtctggc tgttccttaa caaatacaaa ttgtccattc
     3601 ctgataactg gttccattga atcgcctata ataggaacag caaaatcagc attgtttgga
     3661 actctttcaa attcttcttc ctctacaact gtatcgccat aaactaattc agtcgggttg
     3721 gcggcagaag ctgaattttt gattgtcgga agtttttcct ttttaggaaa gtgcaccacg
     3781 tttcctcgat tttgctcttc gagttgctgt tcagcaaagt tgtagacttt tgtttgtctt
     3841 ggtttttcta attgattgta gattgtttca atggatggaa tgttattttt cttatcttct
     3901 ttaggaacat cgtaaccaag caaccatgcc tcactcacat ttaaagtttt agccaacaaa
     3961 taaagcttgt gttggtcggg cgatgactta ccattgacat attgcgatag atgacttttt
     4021 gacattttta ttccagtttc tttttgcaaa ggtaaagaca tattcaaaat atcaacttgc
     4081 tttaaatttc tttcagacat taactgatta agtcgttgct gagtcgtttg cttcatctta
     4141 tacctccttt ctgatactta ttatatacct tattgaacat aagttcaata aaaaagttaa
     4201 attaatttga acttttatgt tgacaatgtt ttatgcagga gttatacttt ggttacaaag
     4261 ttcaaaacat ttgaactaga aaggagcgaa ctaatatgag ttttgattat tctaagttgt
     4321 cgggaagaat tgttgagaaa tatggaacgc aatacaattt ttcaatcgct ttaggtttgt
     4381 cggaaagaag tttgtcatta aagttgaata accgagtacc atggaaaagc accgaacttc
     4441 aaaaagccat tgaattgcta gatattccaa aagaagaaat tggcgaatat ttttttaatt
     4501 tagaagttca aaatgtctga acttaagaaa ggaattcgaa aaaatgaaca cacaaaaatt
     4561 tgaaaacaat ctatttgaat tagaagttaa gacggaaaat ggtgaatcgt tatttaatgc
     4621 tgaaacagta gcaagaagtt tgggtttcgt ggaaacaaaa aacggtaaag aatatgttcg
     4681 gtggagaact gtcaatggat atttaaaaaa atacctttcg caagaagttg cgaaaaacga
     4741 ctttatcagt gagccaatgg tttacaaatt agcctttaaa gcaaacaacg tacttgctga
     4801 aaaattccaa gactggttag caacggaagt cctacctcaa atccgaaaac acggcatgta
     4861 cgcaacagat gaactactta acaatccaga cttgctgatt gaagtagcaa ccaaactcaa
     4921 agaagaacgc acgttacgat tgatagctga acaacgagta aatgaattac aaccgaaggc
     4981 agactattac gaccgaatct tgaacaacaa aggattagtt acagttagta cgattgctaa
     5041 gaactacggt atgagcgctg tatcgtttaa taaattgcta catgaattag gtatccagtt
     5101 caatcaaagt ggcacatggc tgctatacag taagttccaa gacaaaggat acacgcatat
     5161 tgagccattt gattatgaag ataaaaacgg caatcggcaa gtaaaaacaa ggatgaaatg
     5221 gacgcaaaaa ggacacatct tcttatatga aacattgaag aagaataatt acttaccgat
     5281 gattgaacgt gaacaaacag cataggaggt aacactatga acgaggaaat gagccaaaca
     5341 atcaaggtac aaaaaatgat agatgatcta acacatgcaa ttgatagcca agccgataaa
     5401 atcatcaagg aattgcaagg acaaaaagtt tgggatgcaa aaatgctttt caagactatc
     5461 aaatttgaaa tgaatccaac aaaaagaaag ctcgccgatg tgttggaaga aaagttggct
     5521 tccgctatca acgagcaaga attactattt gaaaccgata cttttaacag ctgatgtttt
     5581 atagatgaca gtttcatccg aatctatatc attatagatt cgattattgc aatgtacgaa
     5641 ttataaatac aggaggaaat aaccaatgga gcaactagct ttagttaacc tctcagacct
     5701 taaagcttct ttggcagaat ctgagattgc aaatgaagtg tgggatacaa agcaagctgc
     5761 ggaatattta aaaaccacaa cacgcacgct gactaaagat gccgaatctg gaaagattcc
     5821 agcagcgaaa gttggcagag agtggaggtt tagtagtatc gctttgtatc agtatctaaa
     5881 aggaggaaaa acatgggtaa attcaacaga gcactagtgt tcagcgcacc cctaatcgtc
     5941 tatgctttag gactttgggg aagcagacaa gcattaatcg gcacgatcgt ttacatggtt
     6001 tggattttta tggggcttga tgaagctgag tacagagcga aaaagcccac cgagggggct
     6061 gactaaagtg tggttctgtt tattaggtgt ttatctcgtg gccgttttag taaataacta
     6121 catgagaaaa cgtggcgaat actggtatac atcctatgcg gttctagtat gtctaatgct
     6181 tacaattttt ctaatgattt attcaaaata ggtaatactt tgtcaatcaa ataagtttca
     6241 agagattttt gttctgcatc agtgttgccg taaccaaaac ggcttaagaa aattttcata
     6301 acctctatat cttcattttg aatatatggc aggactgcat aacctgatgc ttttacagca
     6361 gatatatttt tatcagtgtt actaccaata caaataccca cattgttgag aaatgttgag
     6421 aaagttgttt gtattgtttg ggtttttgaa tcgtgttttt gtaattcaat ttctttatcc
     6481 ttcatcgatt caacatgctt attatttata accgctgtaa tcgaagggga tataagagct
     6541 actaaagcta ggataatcga aattgtgatc gtgttatcga aactcatttt ttcaccatcc
     6601 agtttttaaa ccattatatc aaaaaggaga gaagaaataa tgcaagaatt agtaattttg
     6661 aaaaataaaa aaagacacga acgccagcaa gcatgatcgt gtccaaaaga aaaatctttt
     6721 aaaccattat aacacaggag gaaataaatg atctcagtta aagggttagg cgatgaaata
     6781 ttcgaagcaa tgatgagcaa agcacaacag gacatcaaag aaaaaatcat ttctgctgca
     6841 gcgcaaggac aaactagctg cactgttcga tcgagaggaa cgacaccaag ttttcttttg
     6901 gcgctagaag atgaaggcat tttgaatatc aaacgaagag atggcagcgt cagattgttt
     6961 tggcaatttt aggaggccgt gatgaaagat tttgattctt taggcgccag acagcaacca
     7021 ccaaatgaag ctagtcctgt tggagttgat tggcaagaaa atccgttata tccaggtgat
     7081 acttgctatc taacagaaga aggctatgta ccagtagacg caattctaga gtacgtccag
     7141 caacattatc caaagattga attaggagga atttaggaat ggcaaatgat ttaacacaaa
     7201 caacacaacg ttcattagat gagcaggtaa tcagtaatct tggacggtta caagaacaag
     7261 gtttagaaat gccaccagga tatagtccac aaaatgcgtt aaaaagtgct tttttcgaac
     7321 tcactaacaa tacaggagga aacttgttgc agatggctgc aaacaatcaa gaaatgaaaa
     7381 cctccatttc taatgcactt ttagacatgg ttattcaagg gttatctcca gcaaaaaaac
     7441 aatgctattt cattaaatac ggaaacaagg ttcagctaat gcgttcatat tttggaacaa
     7501 tggcggtcct tgatcgtgta actggagggg cagatattac gcctgtagtc gttcgacaag
     7561 gtgatgagtt tgaagttgca atggatggac caaacatggt tgtcaaaaag catgaaacaa
     7621 aattcgagaa tttagacaat gaaatcattg cagcctatgt agtcatcaag ttaacaaatg
     7681 gtaaagagac cacaacagtc atgacgaaaa agcaaatcga tcaaagttgg gctaagtcaa
     7741 aaatgaaaga ttctggaccg caaaaggaat ttccagaaga aatggctaaa cggacagtaa
     7801 tcaatcgggc agctaaaaca ttgatcaaca caagcaacga caacgattta ttagttcaag
     7861 ctgcaaaaga tacgttagaa aatgaatttg acaatgatcg gaaagatata acgccacaaa
     7921 cagaaaaagt ggctactctc gaacaaaaat tcttttcaaa caaaaagatt actgaaccaa
     7981 tacaaaaaga accagatccg attgtgattc cagatgatat ccaaaatgaa gtaactcgag
     8041 ttgctgatgt acctgcccat ccagaaatag agcaagcaca tttgatcgaa aatgaggata
     8101 tcaatccaat tcaagaagaa ttgatagata ttccagactt tggacgcgag gaaggtgtag
     8161 aagatgtctc agaatttgaa gacgacgagt accctttctg atgagaatta ttactccaat
     8221 gaagctgact ggcagtacat gtcaacatca caatataagt cctttttaaa atgtgaagcc
     8281 gcagccttag caaagttgaa aggcgattgg gcaccgacgt cggatcccaa agccttactc
     8341 gtaggaaact acgtacattc ttattttgaa tcaaaagaag tacatgaagc gttcaaagaa
     8401 gaaaataaat ccaaaatgtt ttctagtagg aagccgtatg gattgttgaa agatttccaa
     8461 attgctgaac aaatgattga acgacttaag caagaagaag cattcatgaa catttatcaa
     8521 ggtgagaaag aaacgatcgt gactggggaa ctatttggaa cgacatggaa aggcaagatt
     8581 gattgcttga atgttgagga tgagtatttt gttgatatca aaacaaccaa agacatgcat
     8641 gagcggaaat ggaacgaaaa ctacggatca agagaaacgt tcattgtcaa ttttggttac
     8701 gtacttcaaa tggcaatcta tcaagagctt cttttacagc aatacggaaa gatgttcatg
     8761 ccaatcatcg ctgcggtatc gaagcaaacg cctagtgagg cgaagttgat aacgattgat
     8821 caagataaga tgagctacga gctaatcatg ctaaaagaaa atattgaaag aattgtcaaa
     8881 gtgaaaaatg gcgaagaaag gccgatacct tgcggtacgt gcgagtattg tcgaggtaac
     8941 ctttcaatta ctggattcac tagcatggac gatctttaaa aggaggtgct ttgcgaatga
     9001 atctaggata catcaagtta taccgtaaag tgactagttc attcgtttgg accaattccg
     9061 atatgttcaa gctatggata ttgtgtttaa tgaaggctag tcatgaagat agaaaatttt
     9121 tatttaacgg tcaagaagta cgtttgacaa gcggacaatt cgtcacagga gcccatgcaa
     9181 tagcaaaaga gtacaacgaa ggagtcccga gtgacaaagc aattgcatgg cgaacgctat
     9241 ggagatggct taagaaattt gaaaatgaag aattattgac aatccaatcg aacgctagat
     9301 atagcgttat aacaataata aattggtctg actatcaatc gagtgacaag ccagtgacaa
     9361 gcgacggaca atcgagtgac aagccagtga caacaaacaa gaatgataag aatgataaga
     9421 atgataagaa taataatcct cgcaactctc gaaaaacacg agagtatgca gatgacgatc
     9481 caaataaaaa attggccatt cttttattaa aactcattcg aaagaatcgt agtctcaaag
     9541 aacccgattt gaacaaatgg gccaatacga ttcgtttgac gattgaagct gacaaacgaa
     9601 ctggaaaaga agttcaagac atgattgttt gggctactaa ccatgatttt tggtccacag
     9661 tcatttcatc gccaactagc ttaagaaaaa atttcgatac aatggtgggt caaaaaaata
     9721 aaagaaagca acaaaatatt tctaatgatg agttaccaga aacaggtgag gattggtaat
     9781 gaataaaaaa ctaagtgcaa tggctgcacc ttacggcgga ttaaaaacag cagatcataa
     9841 ttgcccgaaa tgtggtgatc cattgtatat ctggaaaaca aaaaataaag atggtactga
     9901 tcgatgcggt cctacatgta tcaataagat ttgtggttat cgagaaatgg taactaaaaa
     9961 tcaaaaagaa gctatccaaa aagcgaatga agcaatgaaa aaggacgcta tcaatcgaat
    10021 gcttaacagt tcaatgatta cagatgatgc catatggacc ttcgattttg atggatacaa
    10081 agtagttgat caggaaacag cacaaataaa agcgatggct caagaatggg ctaaaaaaat
    10141 tgtaaatggt agcacgattc atgcagtgat aaccggtaga acaggagccg gcaaaaccca
    10201 tctaggcgct gcagtgatta aagaagtcat gagggcatct aattataaaa ttgcttgttc
    10261 atttatcagt tatcgagaac ttttagaaca gttgaaattt gcaatgaatg atccagaagc
    10321 aagaaaagcc gtaacaggtt cgctgatggc tgagataaag aaatcagatt tcgtggtaat
    10381 cgacgatttg ggtgcagaac taggaagaat ggaagaaaac aaccaggcaa cgccttatga
    10441 tgttgatgtt ctcacatcgc tcacagaagc tcgtctaaac aaagctacga tattcacaac
    10501 caatttatca tcgaagcaat taaaacacgc gtacggtgag cgagtgttct ctcgtgtaat
    10561 gaatggaacg aaagggaaca tagctgtatt caaaacaacg acagacaaaa ggaggaatcc
    10621 agtttgacct ttgtagtgaa aaaaatgtgc tacttagata gccgagggcg aggagaagct
    10681 agtgtcgagt ttgctaaaca ccacacgact aaagaagagg ctgaccttgt tgcaagtgtt
    10741 tgtggcggcg aagtagtcga agttattaaa cccaaaagac gattttcaaa acctaagaca
    10801 aagccagtga aaaaagagtg ttgttgtccg aaaagtaacc aagcatggat gagaggtgca
    10861 aaatgacttg tttaaaatgc aacgatgaaa cagttatttg gtataagaca ttgcttggat
    10921 ggtcaacttg tgaaccttgt ccaatatgca atgaaaatgg acgacgttcg aaagaacgac
    10981 tcgaaagact aaagaaggag tatagcaaat ggcaacaaga agcaaatacg gaaacaaaaa
    11041 gcacgaagta gacggcatca cttttgattc tatcacggaa gcagagtatt acgatctagc
    11101 cttgtggcaa gcacaggcga atggttggaa agtgaagctc caggaaaggt ttgagctgat
    11161 gccgaagttt gaactagagg gcaagaagta tcgcaagatc gagtatattc ccgacttcac
    11221 attttacaaa agcggcaagc tggtcaaagt cgtagatgtt aaggggatgc agacaaaaga
    11281 ctttaagatc aaggcaaagt tgttctgtca tcaatatcaa gtgccgttga tattagccaa
    11341 aaaatatcgg aatacgttca aggaagagcg tttttaacga ggtggtccat catgacaaca
    11401 gaagaagtga ttcaaatgcg aattcgaagc cttcggcgtg agattgacga tctggaacga
    11461 acaaaggcag tgatggtcaa tgaaacggct agaaaggcaa tcgatttgca catagagaat
    11521 ttaagaaggg aaatccgtag attggaggaa tgagcgtgga taaggaagcg gcttggcgaa
    11581 aattaatgtt gctgattcaa gatgagaact ggcaagaaga tgaagcagtg gttgctgaag
    11641 ttcagcgtct aggaaagatt gctaacggac gtatacgaaa aaagccagac aaaagaaaac
    11701 agcgcaaagg gaaaatcgtc gttgttttac acgaaggcaa aattttgatg caaggaacag
    11761 ctagtgagct gtctgcagaa actggatata cgcgtgggac tattcgaacg tacgcttggc
    11821 gaaatcacac cgatcgaaaa gggcacgaat ataagtattt ggaggaagaa aaatgaacga
    11881 aaacaaatta atcaaattgg gtgtagcagg agcagtaatc gtaggtattg gagttatcgg
    11941 aggatttaag ttcttcgaaa aaatcgataa tggatatgtg ggtgtgcgct attcaatgaa
    12001 cggcggtatc aaagatgaag cactgacgca aggtgtgaaa tttgtaggga ttgacaaagt
    12061 gatccaatat ccaattcgct tgcaaactat ccaatcaaaa aatatttcag tatctacaag
    12121 cgacggcaaa aagacaacga ttgatatcaa atatgactac aaagttgatt caactaaagc
    12181 agcaaaaatg tacaaggaat ttgggaatat cacttcggaa gatatcgaaa gtggatggtt
    12241 aaaatctaag cttcaaaagg tcgctcgtga agtttatgcg aaatatagtc tgcttgatgt
    12301 cctttcagga gattcctcta aagttgaagc tgaggtatta acgaactttg ctaaatcagt
    12361 tgaatctaaa gggtttgaag tcgaagacgt aacacttggt gttccagatg tcgataaaga
    12421 aacacaaaaa tcaatcgatg cgatcattcg agctggtcaa gaaaatgaaa aagcgaagct
    12481 agacgcagaa actgcaaaaa ctcaagctga tagtgaagct tacaagaaaa caaaagctgc
    12541 agaagcagag gcagaatcta atcgcaaagt cgccgaatca gtaacagaca atttgattcg
    12601 ttatgaagaa gctcaagctc gcaaaaagca tggatgggta acagtaaatg gagcagatac
    12661 tgtagttacg gatgaagcag gcaaataata tgggattctt tatggctaaa attctcttgt
    12721 tcttaggttt agtaggagca gcatatctcg tgtatgcgct cctttcccaa actgatgaca
    12781 aagaagatga caacaacgat gaaatgaaat tttaggagga gaaataatgg acgaactaat
    12841 cacaaaagta gagcagtggg ctaaagacaa gggactggat caagcagatc caaaagcaca
    12901 gtttttgaaa gtagctgagg aattcgggga aatagcttcg gcgatggcaa gaagtaatga
    12961 tgaactattt aaagatagcg taggagacgt tatcgtcacg ctgattatcc tttccatgca
    13021 aaaagggaca aacgtacaag agtgtttaga aatggcatac aacgaaatca aaggacgcac
    13081 agggaaaatg gtagatggtg tattcgtgaa gtcgagtgat ttggagggca gcaaatgata
    13141 aaaaagctca ttcaattcag catggattta tatgatatcg aatcaggagc aacactatct
    13201 gtggaatcgg accatctaat cataaatttt ggtggaaagc gccagattat tttgtgggta
    13261 gttgatgatg tactgtttcc agaaattgtt catgatttcg aagaatcaaa agcggttgag
    13321 tttgaaatag tgaaaaaagt aatggaattg attgaaaaat acgaggagga cagcgaatga
    13381 taccgaagtt tagagcgtgg gataaacgaa agaacgtaat gagagatgta gccgtcttgc
    13441 attttactaa aaacggcaaa acaaacttta ttgaatattg gataaatcct accgaattga
    13501 aatcatatca cgtgcgaaac atcgacctca tgcaatccac aggaatgaaa gataagaatg
    13561 gtgtggatat atttgaaggg gatatagtat tagtcagcgt gcgaaatggc ttcgattact
    13621 tagataataa agtttgtatt gtcaaaaatt caatagatta ttccggatta gtttgtgcca
    13681 ctgttgatga agacttagag tatcaaattt ttaacacaga gctgtttgaa gaatacacgt
    13741 atgaagtcat cggaaatata tacgagaata gcgagttatt ggaggtagag tgattatctt
    13801 agctactgac tacatcgatt ctttaaaaga tgaaaatggg aatgtcccag cattgctaaa
    13861 ttgtggaatt aaaagcaaga atagaatcat tttgttacgg atatcggctg atttagcaaa
    13921 atatctttat ctgagcaaga cagcagtata ttacactgcg gctacacgtt atcagtacaa
    13981 gggaaaaaca atcagtcagg attattatga tcgtttaatc agtcctgata tgtatgggaa
    14041 ttcagaatca gcaattaagc tgtttggcgc aatagagata tatgccgatg attttccaaa
    14101 tttatggttg aaggaggaag cggaatgaaa tacgaaatac cactaagtga agcagacgtc
    14161 cagtcaatta ttaacggtcg ggaggttaat aaaaaacttc ctgatggtac tgaattagtc
    14221 atcagacaaa gttatttgaa agatatggca gctccagtat taattgatcg ttttaacgtg
    14281 actgattctg tggtagagaa ccacttgaaa gaatttcgat caagtataaa cgacactttc
    14341 agattaggga gttgattgac aatgaacacc agacaccgca gagtagcaaa actaagaaaa
    14401 caggaactga atgtactaaa gacaaagttt gaaaaagaat atggaatttc agcagaagaa
    14461 acatataaag tggcaagtca gtgtgttgct gatgcaagtg atgctattcg taagtttgga
    14521 atttcgatat taagtgatga tcgtaaatgg gaggaaaaag aatgaaacta aaagacggat
    14581 tttacgctag cagtcacggt atcggcggtt taatgctaga tatgccgaca aagaatccta
    14641 aaacacgtaa gaaaccaaaa gtcaaagtcg gtgacatggt ccgctgtgaa gcagaggagt
    14701 tcatttatcc atttcgtgga tatgtagaac acgtctataa tcactcagcg atcattcgca
    14761 ttgaaaacac gatggaatgt gataaatgga cagctaaaag caaagagaat ttagcagtag
    14821 tgagattggt ggatatggaa ctaatcaatg acaaataaaa aagccggatc gctccgacta
    14881 acataataaa acagacaagt ttattatatc acataaaagg agcagtttga attgatgcaa
    14941 ttgttacgag aggtagattt caaacagaca agatgtaatg cgagagatgt gctgaagaac
    15001 tttcggcgtt tggagcggat ggcaggtcgc tctttgatag atattaagtc gccgattatt
    15061 acggatatgc cgaaggcacc gaagcacggc aataaggcag aggatgcatt gattcagatg
    15121 atggatatag aagcggagag agacgcgatt ttagcggctt tgatggctct tagtctgatt
    15181 agtcgtcaga tactctacta cagtttttgt gtgccagaca gcttctcaaa ctacagaatt
    15241 agccgtgaag tgggttattc agaaagaagt atacaacgga tgaaatcgga agctctaata
    15301 gagtttgcag aagcatataa acacggaaga ataattgctt ataaataggg ggaccatata
    15361 atgtggaaag attatgtatc gttgaaagag ttgaaaaaag atcttgtttt caaaagaatt
    15421 gtagaatggt cagagagtga attaatttta gaagatggaa ccaaaatgga agttgtatgt
    15481 agcgaatcag attgctgcgc atgggccgaa ggtgaattca aaaatgtaaa gcttgatgca
    15541 gtgattacag atataaagat ttttgataaa ggtaaccgtc tctataatgg tgacggacat
    15601 acctcttatg ctgaagtcgt tgtttatcat aatcgtaatg agatcgctaa agcagaatgc
    15661 acagcgaatg atgggaatgg cggctactat tatagtgttt gtgctttaaa ggtcaaagac
    15721 aaactttgta tagtgactga cgcataaaaa aatggcggtt ttttggcgga atgatggcgg
    15781 tttttagcca tttatcagtg atattatggt agtgtcgaaa gattagtgat aggtctgaga
    15841 caaaataata ataaaaggaa catcgtttta ttattgtttc acaattaagc ttcgatagac
    15901 agcaacggaa atattaagaa taaggatgtg aattttaact ccttctaaat tgttcttatt
    15961 atctatcatc cgttgctgtt tattgttaca tacagatcgc ttaggcggtc tttttatttt
    16021 ggccgaaaac ctacattttc gatggccgat tattggagga ggaatagcat gttcaaacta
    16081 tctgaaatca ttaagaagtc cgacgttgag aaattagaga tgttaaaaaa gaagttgaag
    16141 aaatagcagt ctcttcgtga ggctgtttta ttttgctcac aaaaatagac cactatcggg
    16201 taatagtggt caggaattaa atgaaaaaga tgttagggtt gttagctaag tataacatca
    16261 taacgcttac aaaacaatgc aagaaggata aattattatg agaacttact ggtatgtgtc
    16321 attaaacaat aaatatccga agccaatgaa aggacagcat aggcgtgtag tcatgtctgt
    16381 tcaaatgaag gcgaagtatt cgattgtaga aatgctaaga gaagctacac caaaagagat
    16441 tgatcagtat aagttggttc ttattggcat tggttggttt aaggatgaac atattcaaac
    16501 aaacatgaag aggtggttga gatgaagtta tattatgttg aaaaagcaaa ttgttgggtg
    16561 gttgaaggct gtctgtcaaa gtacgctaca gatattatat ctactcaatt ttcagagttg
    16621 ggattgaagg ttatcttttg tggtgagttt gtcagtgtga aagaagcggt attgccaatg
    16681 acagcaaaga gcagacgctc gcgtggttca agtt
//
LOCUS       DAFLWC010000066        16403 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.067, whole genome shotgun sequence.
ACCESSION   DAFLWC010000066 DAFLWC010000000
VERSION     DAFLWC010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16403
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.067"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(23..670)
                     /locus_tag="L1V17_002042"
     CDS             complement(23..670)
                     /locus_tag="L1V17_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236795.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(849..1568)
                     /locus_tag="L1V17_002043"
     CDS             complement(849..1568)
                     /locus_tag="L1V17_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1236796.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(1699..2850)
                     /locus_tag="L1V17_002044"
     CDS             complement(1699..2850)
                     /locus_tag="L1V17_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBN1236797.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(3067..3807)
                     /locus_tag="L1V17_002045"
     CDS             complement(3067..3807)
                     /locus_tag="L1V17_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBN1236798.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(3811..4134)
                     /gene="rsfS"
                     /locus_tag="L1V17_002046"
     CDS             complement(3811..4134)
                     /gene="rsfS"
                     /locus_tag="L1V17_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBN1236799.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(4191..4784)
                     /gene="yqeK"
                     /locus_tag="L1V17_002047"
     CDS             complement(4191..4784)
                     /gene="yqeK"
                     /locus_tag="L1V17_002047"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBN1236800.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(4768..5418)
                     /locus_tag="L1V17_002048"
     CDS             complement(4768..5418)
                     /locus_tag="L1V17_002048"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBN1236801.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(5428..5739)
                     /gene="yhbY"
                     /locus_tag="L1V17_002049"
     CDS             complement(5428..5739)
                     /gene="yhbY"
                     /locus_tag="L1V17_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HBN1236802.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(5755..6864)
                     /gene="yqeH"
                     /locus_tag="L1V17_002050"
     CDS             complement(5755..6864)
                     /gene="yqeH"
                     /locus_tag="L1V17_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HBN1236803.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(6861..7388)
                     /locus_tag="L1V17_002051"
     CDS             complement(6861..7388)
                     /locus_tag="L1V17_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HBN1236804.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(7568..8353)
                     /locus_tag="L1V17_002052"
     CDS             complement(7568..8353)
                     /locus_tag="L1V17_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HBN1236805.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(8346..9215)
                     /locus_tag="L1V17_002053"
     CDS             complement(8346..9215)
                     /locus_tag="L1V17_002053"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBN1236806.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(9216..10595)
                     /locus_tag="L1V17_002054"
     CDS             complement(9216..10595)
                     /locus_tag="L1V17_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBN1236807.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(10603..11022)
                     /gene="fabZ"
                     /locus_tag="L1V17_002055"
     CDS             complement(10603..11022)
                     /gene="fabZ"
                     /locus_tag="L1V17_002055"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBN1236808.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(11047..11523)
                     /gene="accB"
                     /locus_tag="L1V17_002056"
     CDS             complement(11047..11523)
                     /gene="accB"
                     /locus_tag="L1V17_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBN1236809.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(11526..12761)
                     /gene="fabF"
                     /locus_tag="L1V17_002057"
     CDS             complement(11526..12761)
                     /gene="fabF"
                     /locus_tag="L1V17_002057"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBN1236810.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(12780..13517)
                     /gene="fabG"
                     /locus_tag="L1V17_002058"
     CDS             complement(12780..13517)
                     /gene="fabG"
                     /locus_tag="L1V17_002058"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBN1236811.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(13529..14446)
                     /gene="fabD"
                     /locus_tag="L1V17_002059"
     CDS             complement(13529..14446)
                     /gene="fabD"
                     /locus_tag="L1V17_002059"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBN1236812.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(14553..14777)
                     /locus_tag="L1V17_002060"
     CDS             complement(14553..14777)
                     /locus_tag="L1V17_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBN1236813.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(14830..15792)
                     /locus_tag="L1V17_002061"
     CDS             complement(14830..15792)
                     /locus_tag="L1V17_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBN1236814.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(15802..16242)
                     /locus_tag="L1V17_002062"
     CDS             complement(15802..16242)
                     /locus_tag="L1V17_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1236815.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
BASE COUNT         4333 a         3730 c         2797 g         5543 t
ORIGIN      
        1 taattcaatc atttaaggtc atttattcta tatataaatc caaatctgtt tcaggatatt
       61 ttaatttgac aagcgaaata atcattttca gttcttccat gttttctgga tattctgggt
      121 caaatacctt gctatgacgg ccaatcccgc cattgtcgat caatcggtaa attcgattcc
      181 attcaatgaa ttggtcaatt gattggaaat tgctgattgg atagccgcca caatccaaaa
      241 tctctgatac acgaaatgct aggtatgcac tatcgatcac tttatttttt ttcgtgtcta
      301 tcttctcatt tctttcgata agaatttttt caggacgatg tttcaagctc cactctaata
      361 gtagaaagaa agcctccatc cgatactctt cttcaaataa ccgaaaggct gaatcagaac
      421 gacgaaaaag cagcggaatc agataatttt gtctataaat cagcattggt gcgcggtcca
      481 ccatacactc taaataacgg ttcagatacc ctgtaccgac atagtttcct aatcgatagc
      541 cttcaacgcc gaatcttgcg tatttttgcg ctaattttga acaatcagtt acgttcacag
      601 ctaactcttc tactttgcgg taaccgctta agatacgttc aaaaggttct aaagtgattt
      661 ttgcttccat attcttcccc gtccatcttc cacatacttc atatcatttc acatgatact
      721 tatgctctca tcataccaca ggttgaatta gaaaagaaaa taaatcacac aaaaaagcaa
      781 gacaatctgt tagtgagatt gtcttgcttt tcgaaaaaga ctgaatactt ttcgttaaaa
      841 ctggttgctt agtcttctaa tgccacatta tggaacacat gctgtacatc ttctagatct
      901 tccagtgcat caatcatttt ttcaaatgtt tcttgatctt ctggagatag tgttacctcg
      961 ttttgaggga tcatttggat ctcagcgatt gaaaaatcag tgattccttt ttcttttaat
     1021 gcttcttgta tactatggaa atccgctact tcaccgtaaa cgatgatttg tccttcttct
     1081 tccattacat cgcgaacatc gatgtctttt tccattaggt attcaaggat ctcgtcagcg
     1141 tcttctcctg caaaagcaaa gattgctgta ttgtcaaaca tgtaagaaac cgctccggaa
     1201 acacccatgt tcccgccatt tttcccaaat gctgcccgta cgtctgctgc tgttcgattc
     1261 acattgttcg tcaatgtatc aacaatcacc attgagccgc ttggtccaaa tccttcatag
     1321 cgcaattcag agtatgtttc atctcctgca ccttttgctt tttcgattgc tcggtcaata
     1381 atatgttttg gtacattata agttttagcg cgatcaatga cgaaacgtag tttttggttt
     1441 gcatgcggat caggatcacc tgattttgct gccgcgtaga tttcaatccc aaattttgca
     1501 taaatccggc tattattagc atctttagca gttttctttg ctacgatatt tgcccattta
     1561 cgtcccatat tttcacttcg ctttctgatt tgatagtttc ataacgcaaa aacgtcctgt
     1621 tccattatac ttgtgaatca cgattctgtg aagctttttt tctttcttcc ttcattcttc
     1681 tcatttttag tcaattatct atactcggat tgggatttgc ccgaaattct gttccggaat
     1741 attgcctccc aattgataga tttgatcact tctaactaac agttccgctt cttgtgcctc
     1801 tttttttccg attcgggaat aaatagaaat ctcttttttt tcttttaaga atcttcttcc
     1861 agcatcggta aatccaagta gtcgaagata atttttattt tgttggacag gaatctcttg
     1921 ctttttgata ttcagcaaga cataacaaga taatcgttgg atccgtgtcc atgtatatct
     1981 ttttgttttt acctttgaca caaaatcctc aaaactatca gcagttgcag ctgctgtttt
     2041 catgcgcgat tctattcctt cggtcatctg atagatatct gtcagttcca gcaaagtaga
     2101 agataacaac cgataacgca aatacggcca ataagattcc caagtctgca gcgaacaagt
     2161 tgaaagatct tcttctgtct gaggcggcac aagtccagct attctttttc cttcttctaa
     2221 cgcatggcga atggctgttg cactggctat cctctgatct gtgatgattt tttcatgata
     2281 gcctgcactt ttacgtcgga tcggatgtaa ttccataggg tggacatact tggcattttc
     2341 ctttgcataa cttaatccca agatatgatt tggcgaagaa aaatcaagcg taatatcggg
     2401 atacagactg cgaaaaacct cagtcatttt ttgcggataa ctatacgttt gatcagacag
     2461 ttcttgaaat gcctcttcta tcctatcttg attctcttgg acaaagcgtc cgaaactgct
     2521 gtaatcaaac gaagtctctt cttctgttcc aaaacacaaa ctgtcacagt ccagtgtttg
     2581 caagattttt actgcacctt tagcaaaata gtcagctgac tgaaccgccc attcgacggg
     2641 aagctccact actaaatcca caccattttg taaagcttca ttcgcgcgat gccatttatc
     2701 gatgatagcc ggttcgcctc tttgcaaaaa attcccgctc attacagcaa tgacgacctc
     2761 tgctcctgtt atttttcgtg ccatttccac atgatagcga tgtccattgt gaaaaggatt
     2821 gtactctacg ataatcccgc agcttttcat gcgcatcctc cttcatagtt atcgataaaa
     2881 aagaaataga gacaagtaaa aaaaggcaaa aatcggaaaa aatacccgaa ctatataaac
     2941 tattctcgca aacacaatac ttctgcgacg aaaagctgca ctgcaagagc aatgcctata
     3001 tcgttcggat atataattta tgttgaagat ttattctttt cttgttaact cgagcaggca
     3061 aaaccgctag tctttgtatg ctacaaagaa ccagcgcttt gatttctctg atgctgcttc
     3121 gtctgtaaaa tcagaaaatg cttcgacttt cgaaaagccg ctgttttcca gcattcttaa
     3181 ataactttcc aatggatagg tacgctcttg atgtagttca tcttcacgaa taaatcgacc
     3241 agacccttct tgttcttcaa cgaaaaaggt aagaaaatgt tcgatgctgt gtttctcgct
     3301 tcctggataa ctatcccaca aaaaagcaaa attatcccct tgataatgat agctatattc
     3361 tggaaaaacc tcatctactt gataggtgga gtgtacgtca aataaaaatc ggccattttc
     3421 ttctaacgct tgatagactt catcaaacac ttgctgtacc tcttgtctat ttttcatata
     3481 gcacagcgaa tcagaaaaac aggtaattgc ctgatattgt ccgatttctg ataaatcgag
     3541 catattgcct tccacaaatt ggatcgatgc gtcttcttca tatgctcgct ggctggcaat
     3601 catcaacatc tcttctgaaa ggtctaaccc tgtcacttta tatccatctt ttgcaaaggc
     3661 aaccgctaat gctccagtac cgcatgccag ttccaaaata ttttttgtgt cttcttgtaa
     3721 atgacgtttc gaaaaagcta accattgctg ataaagtgtt tcgtccatca cttcatcgta
     3781 aatgaaagca aatgtttcat aagccatatg ttaatccaac cattcactaa gatcgactag
     3841 cggagcatct gaccatagtt tttccagatt atagaaattt cgttctggcg catggaaaac
     3901 atgtacgatc acatctccaa gatcgatcaa tacccatttt ccgccttctt ttccttcaat
     3961 acgttttact tcatatttgt tttcttcttc tttatcaatg atttcttctg taattgcgtt
     4021 gatttgacgt tcgctatttg ctgaacagat catgaaataa tctgccaaca aggaaacatt
     4081 tcgaacgtct aaagcgataa tgtcttctgc ccgttttgaa tctgctgctt caatcgcaat
     4141 ttttaattgt tctttactat ctatgatgat ttcctcctaa tatgagcagc ttattttttt
     4201 gctacccagt aattatatgt ttcgattgtt tttggataaa tctgttgttc ttgcgcaagc
     4261 aaatgggcca atgtatgttt tgtttcaaat gctacagctt cgtctagatc agcccatgca
     4321 atggctcgtg catcttgtac cccaggaaaa tctcgacctg gttcaatata gtctgctaca
     4381 taaatgattt tgtcaaggag actcatctta gcagccccag tcgtatgcac ccggattgca
     4441 tgaagaatct ctgcatcggt gattcctaat tcccgctcta caaacgaagc gccaacaaga
     4501 ccatgccaga ttgcattatt ataattcaat aactccggat caaaaccgtc tcttacgatt
     4561 accattttga actcctcatc tggtcgttct tttgcataat catgtgtcaa tgcagcaata
     4621 ctagcttttt caggagaagc accgtatttt ttggcaagag ccacggctgt ttcttctact
     4681 ccaagcacat gcttgaagcg ttgttcgctc attctcatct gtattttttg catcaggttt
     4741 tctctagaat aagcagtata ttcattacta tagtccatat tcatacaacc cttcattttg
     4801 aatataatca attactttat ctggaacaag gtagcggata gaacagcctt ctttgatctt
     4861 ttgacgtatt ttcgtggaac tgatgtcgat ctcaggtaca tctacccaaa ttacaggata
     4921 tggagtatcc gttgtgtatc ctggtcgacg tatacccaca aagttgacca tagaagtcag
     4981 ctcatcgatt ttataccatt ttggcaaata ttctaccata tccccaccga taataaagta
     5041 ataatctgta tccggattgt tttgcgtcaa ttccttcata gtatcatagg tgtaactttt
     5101 cccaccacga gctaattcaa tcgtttcaat ctgcaaaaaa ggattgtctt ccaccgctaa
     5161 ttccaacatg ttgagtcgat gttttgcatc aatcgtctgt ttctcatcaa catgaggtgg
     5221 ctgataagaa ggcatcaaaa atacgcggtc aagacctaaa ttccggccag cttgttcagc
     5281 catcactaaa tgtgcaaggt gaacgggatt gaatgttccg cccaagatcc ctacttgctt
     5341 tttcttctct aagaattgag gcatttcttc aggaaataat tgtgaacgaa caaatgtctt
     5401 agcttgcgta ttcatcatgg tcactcctta tattgctttt acttcttttg atagcctttg
     5461 atacttttct tttgtggaag gtttgtataa tacaataaca cgtccaatga tttggacgat
     5521 ttcgcaatct atttcttttt ctaatacttg agctgcttct tctgcaatct catctgtatt
     5581 ttgaagtaac gatactttga tcagttctct tttttctaaa gcttcttcaa tttgaacgat
     5641 cattgctgaa ttgatcccac cttttccgat ttgaaaaatc ggctgaagat gatgcgcttt
     5701 gctacgtaaa aaacgctttt gttttcctct taaactcata attttccttc ttccttaaat
     5761 caatgctttg cgtttcaata catctacacc ctttggcgcc cagcccgcaa ttactactgg
     5821 cgctgttaca gtgatccagc ctagaccggc aaaaacgatg tctgtttttt ctttcacaga
     5881 aaactcaaaa cgaacaagct ccggaaatgc ctcgacttca tcaggacgag gaggctgtaa
     5941 taatccacct acatgttttt gataaaattc gtctgctttt tccagtttcg ttcgatgaat
     6001 atttacatca tttgacacat aagcaataaa tgaagcacga ttgccgctga taaaatcaaa
     6061 tcttgcaagt ccgcccaaga aaagtgtttg cccttcattc agctgataaa ctttaggttt
     6121 gatttctttt aacggtgcaa tgatccgcaa atctttttta cctaagtagt gcgccatttg
     6181 atggcgatgg ataattcccg gtgtatcaat caaaaaatgc ccgtcatcta aaggaatctc
     6241 gattttatcc aaggtcgttc ctggaaactg cgaagttgtg attacatctt gtactcccgc
     6301 tgtatttttg atgatttgat tgataagcgt cgattttccg acatttgtta ctccgacgat
     6361 atagacatcc cgtccatcgc ggtattcttc gattttttct aatagttccg tcatctcatg
     6421 agatttctta gcactagtta ataatacatc tactggacga attcctgctt cgtaagcacg
     6481 ttccttcatc cattgtgtta atttagtttt tttcaatgat ttaggtaata tatccacttt
     6541 gttcccaact aaaagtactg gattgtcacc gacaaaacgg tgtagtcctg ggattagtga
     6601 accattgaag tcaaaaatat ccaccacatt gacgatcaat gcatcttttt gccctaattc
     6661 attcagtaag cgcaaaaagt cgtcatccgt caatgagaca tcttgggtct cattataatg
     6721 gcgtaatctg aaacaacgct gacaatagac ttccccggaa gctaaacctt tttccaaagc
     6781 cgtttgcggc gtgtatccta attcaccggg tttgtttgtt tgtataacgg caccacagcc
     6841 gatacattgt aattcttctg tcattcgatt ccacctcgcc agcccatatc agggtgtttt
     6901 gctaatagat aggccataat tcttttttcc caaaaacgat taaattgtgt cttccaacta
     6961 tctgttgcga taatgggttt tacaaggatg ctacgtatcc ctgcacgatt ggctccacgt
     7021 atatcagtca taatctgatc gcctaccatt actatctcat catctgctaa atccaattgt
     7081 ttctttgcta tgttgatccc tcttgctaaa ggtttcattg ctcgtgcaac atacaaaaga
     7141 tcaaattttt caatcgctcg cgcgacacgt tttgaattat tgtttgaaac aacaacaaca
     7201 gggattcctg catttttcat ttctaaaatc caagtaagca actcttctgt tccatctgga
     7261 ttattccatg caatcaacgt attgtctaaa tcggtcaata ctgctttgat gcctagattc
     7321 tttaattggg caggtgtaat ctgatagatg gcttctacca tccatgttgg tttgtaattt
     7381 gaaaacatgc tgtctcctca tctgcaaaaa atgaaggagc acataaagta ctcctcaacc
     7441 ccgtattata ctgcatatca gcaaaaaaaa ctacctctat actcgttcgt ctttcagaaa
     7501 aagcatttct ttacaaaatg accaaaaata aagattgatc acagaaaaat ttagaaacaa
     7561 aaaacaacta atattggcgg aacctcttgt atcgtttttc cagtaattta tgctgatcta
     7621 atcgaacaag ttccgtcaat ctttcaatca acgctttttt cataatgtgt gcgactttat
     7681 atcgtggcaa ctgctcgccg ttgaacgttt caggaataac tcgatcaacg attcctaact
     7741 cgcgtagttc tggcgcagta attttcatca actcagctgc ttctgcggcg cgactaccgt
     7801 ctttccacaa aatcgacgca aatccttctg gagaaagcac agcataaatc gtttcttcca
     7861 gcatccagac ttcatccgct aaacctagag caagggcacc gccacttcca ccttcaccaa
     7921 tgatgatggc gatgatcggt acctttaaat cagacatttc gagcagattt ctggcaatag
     7981 cctctccttc gccgcgctct tctgctccta caccgcaata tgcacctgct gtattgatca
     8041 aggtaatcac cggtctattg aacttttccg cttgtttcat cagtcgtaaa gcttttcgat
     8101 agccttcagg atggggagaa ccaaaatttc tgcggatatt ttcctgcaga tcccgtcctt
     8161 tttgaatacc gatcactgtt accggtttgc catctaatcg agcgattcca ccaacaatcg
     8221 cttcgtcatc tgcaaataaa cgatcaccat ggcattcctc gaaagaatcg aagatctctt
     8281 caaaaaaatc caagcttgtc catcgttctt tagctcttgc taactgaacg acatcatgtg
     8341 ctgtcttatc cacgatctat ccatcctttc tgtgtatgca attcaagaag cgtatggatt
     8401 ttctgtttca attccatgcg gggaacaatc tgatcgacaa aaccatgaga taataagaat
     8461 tcagcctttt ggaaatcttc tggaagttcc tgcttgatcg tctgttcgat gacgcgtctt
     8521 ccagcaaaac cgatcaagct ttggggttct gctagaataa tatcgccttc cattgcaaaa
     8581 ctggcagtta ctcctccggt cgtcgggtcc gttaaaacag ttagataaaa aagaccttca
     8641 ttgctatgcc gtttgacagc agcagagatt tttgccatct gcattagaga aaagattcct
     8701 tcttgcatcc gtgcgccacc tgaagctgtg aacaagacga ctggaagact ttcctttgtt
     8761 gctcgttcga ataatctggt gatcttttct ccgacaatcg ttcccatact tcccatgata
     8821 aaattaggat ccatcactcc aataatgaag ggaatcccct gaatggttgc tttaccagtg
     8881 aggactgctt catgaagtcc tgttttatct tgcatttttt taattttttc cgtatattcg
     8941 ggaaatgcta gcggatcttt ggttacaaga tccgtatccc attcttcaaa acttttttca
     9001 tcaataatca aagctagacg ctgccatgca ccgattcgaa aagcgtatcc gcaatgaggg
     9061 catacttttt cttcaccgat gtctttcgta taaaggatat gtttgcaatt tggacacttt
     9121 gcccacatgt tatcaggaac agatggcgag ttagcaggtt tgctctctct attaggattg
     9181 atccgaatat atttcttttt cttaaacaga gccatctatg cgcctcctat ctccgtttct
     9241 ggtgtccaat tcggtaaaaa ttcttcttgt aaaaatgctg tgctgtaatc acctgctatg
     9301 actgcaggat gactaatcaa atccatctga aattctgcgt tcgtgatgat tccttctgtg
     9361 ataaattcac ttaaggctcg ctgcatcttc attaatgctt caaaacgcgt atttccatgg
     9421 acgattattt ttgcaatcat tgaatcataa tatggcggga tcgtatatcc cgggtaaact
     9481 gcactgtcta ctcgcagtcc catcccacct gctggaagca gtaagttttg gatcttccct
     9541 ggagaaggag caaaatggaa agcaggattt tctgcattaa tccggcattc gattgcgtgt
     9601 ccttggaata ctacttcttc ttgacacaca ttcaaaggct caccggctgc tatctccacc
     9661 tgttttttta ctaaatcgat tcctgtgacc atttctgtta ctggatgttc cacttggatt
     9721 cgagtattca tttccatgaa ataaaaatcg ccttcttcat ccatcagaaa ctcgatcgtt
     9781 ccggcatttt cataattgac tgctttagct gctcgaacag cagcgtctcc tagtgcttct
     9841 ctttttgttt gtgagatcac tacagaagga gattcttcca gtactttttg attgttgcgt
     9901 tgtaaagaac aatctcgctc gcctaaatga atgacatgac caaatcgatc acctaagatc
     9961 tgaacttcta tatggcgagc aggataaatg attttttcca aatacatatc atcatttcca
    10021 aatgccgctg ctgcttcttg ctgagctgaa gaaaaatgct gtgggagctc ttcttttgat
    10081 tgaactttcc gaatgccttt cccgccacca cctgcagctg ctttcagcat cactggataa
    10141 ccaattctgt ctgctatttc caatgcttct tctactgtag ataatacacc agtacttcct
    10201 ggaatgactg ggacatttgc ttcttgcatc aattgacgcg cattgatctt atttcccatt
    10261 gcatcgatcg ttgcactttt aggaccaata aatgtgatat tgcactcttc acacatggag
    10321 gcaaatcggc tattttcaga taaaaaacca aatcctggat gaattgcttc ggcttttgtc
    10381 acgattgcag cgctcagtac ttcctgaaca ttcagatatg aatcaacggc ttttgccggg
    10441 ccaatgcaga ttgcttcatc tgctaactgt gtatgaagtg cttcggcatc tgcttctgaa
    10501 tatatcgcta cggtttggat ccctagttcg cggcatgcac gaatgatacg tacagcgatt
    10561 tcaccgcggt tagctatcaa tactttagaa aacatatttc acctatccaa tcataaaggt
    10621 taattccgct tcggctactt ttttaccgtc tactttagcg attcctttgc ctattccggc
    10681 tgaagctttc actttcaata tctcaacttc aaggtataag gtatctcccg gtgtaacttt
    10741 cttacggaat tttgctttgt ccaatccgcc gaaataagcc gtctttccct tgaattgttc
    10801 aagagaaagt aatgcaactg ctcctgcttg agccattgct tcaacaatca atacccctgg
    10861 cataacaggt tcttctggaa aatgtccttg aaaaaagggc tcattgatcg ttacattttt
    10921 cttagcaacg atccgttctc cttcaaccat ttcttccact cgatcaatca aaagcattgg
    10981 ataacgatgt ggaatgattt cttttatttc ttgtatgttc attgttttcc ctctttcctg
    11041 ctttgcttat ttttgctgaa tcctaaagag tggctgtcca tattcgacaa ctgactcgtt
    11101 ttctacaagg atttctgtga tcactccgtc ggcctcacta gttatctcat tcatcagttt
    11161 catcgcttca ataatgcaga taacttctcc tttggcaact tgatcaccta cttttttgaa
    11221 agctggtttg tcgggcgctg gttgcagata aacgattccc acgattggcg aaacaacctc
    11281 gattccatca aatactgccg attctttttc tttcattatt tctggagcag ttgttgcttg
    11341 ttcaggtatg acattgactg gctccgaaac tggcaacgtt tcgtttgttt gaaccatatt
    11401 catgcctcga cttgttttat ttttattcat atacaattca aattgacctt cacgcaaatc
    11461 gaattccgtt agcgaggatt gatcaaattg actgactaat tctctgattt cattgatatc
    11521 caaaattatt cctcccagcg tttcatgcac agaaccgcat tatgtccgcc aaaccctaat
    11581 gaattactca ttgcataagt aaaacttgca ggtttgcttt cgtttttgac aactgtcaag
    11641 tcaatctcag gatcttgttt ttctacattg atcgtaggtg ggataaattg atgttctaat
    11701 gccagcaaag ttgccaaggc ttcgatcccg ccggctgctc ccaataaatg tccagtcatc
    11761 gatttcgtgc tgctgacgta agtatctctg aaattttcac ctaatgcgat ttggattgct
    11821 tttgcttctg cctggtcatt ggctggtgta cttgttccgt gagcattgat atatccgact
    11881 tgttccggct gtacaccagc ttcttccatc gcaagcttca ttgctttaga tgcaccagaa
    11941 ccatctggag taggagctgt catatggtaa gcgtcacagt ttgcaccgta tccaacgatt
    12001 tctccataga ttttggcacc gcgagcttgt gcatgttcta aagattcaag aactagaacg
    12061 cctgctcctt cacccatcac aaaaccattc cgattttcgt caaacggaat cgaaccacga
    12121 ttaggatcag ttgattctga gagtgctgtt aaagctgcaa atccagcaat ccccatctca
    12181 caaatcgttg cttctgttcc tccagcaaga atgacatcag aatagccatg tttgatgtta
    12241 cggaatgctt ccccaattga attcgttccg ctagcacaag ctgttacgat agctgtacaa
    12301 ataccttttg cacctacacg caaagcaata tttccagctg ccatgttggc aatcgccatt
    12361 ggtacgaaca ttggagaaac tcgttttgca cctttttcat gtagacgaat aacttggttt
    12421 tcgattgttg gaagaccacc gatcccagat ccgatgatga cgccaaaccg gtcttgattc
    12481 attttttctt tatctaaacc gctcatctcc attgcttcta aagcagcgta gattccatag
    12541 atcgaaaaca tatccattcg tttgctatct tttttaataa aatatttatc gtaagggaaa
    12601 tctttgactt cacccgctaa ggtaatccct gtttctgaag catcaaattt agtgatcggt
    12661 gcgatgccat tcgtcccctc ttttaagcta ttcaaaaagc tgtctgcgtc atttccaata
    12721 ggtgaagtga ctccatagcc agtaattacc actcgattca tttgtttgct ctccttttct
    12781 tatccgtgca tgaccaatcc gccatcgaca ttgatgactt gtccggtgat atatggattt
    12841 tgtgctaaga aaactgctgt ttgtgcaata tcttctactt gtccgaaacg ctgcatcgga
    12901 atttgctttt ccgcttgttc cttgactttg tctgctaaaa cttccgtcat atcagttgtg
    12961 atgaatcctg gcgcaatggc attacatgta atgcctctag ttgcagcttc tcgtgccaca
    13021 gattttgtta atcctactac gccagcttta ctagctgcat aatttgcttg accaatattt
    13081 ccaatcaacc cagatacact agagagatta atgatggccc cttctcgctg cttcatcatt
    13141 tttttcaata cgtgctgcgt catattgaag gttccaatca aattgatatc cagacatttt
    13201 ttgaaatctt ctgcatccat tcgcatcaca agtttgtcat ttgtgattcc ggcattgttt
    13261 actaacacat ggatcgatcc aagcttttct tctgcttctt tgatcatttg tcccgctttc
    13321 tcataatcag agatgtcacc ggaaactcct acgcatttta caccgaatgc ttcgatttct
    13381 tctatctttt cttttggaat ctctccgcga ccattcaaaa tgatatttgc tccagctttt
    13441 gcaaaagcta aggccatcgc tttgccgatt cctcttgtac tacctgtgat aaatacattt
    13501 tttcctttta catccataac gttcctcctt atagtattgc tattgtttca tcaaatgtct
    13561 gcttattctc aacacgcaga actggtattg ttttatcgat ttttttcata aatccgctta
    13621 atacttttcc ggggccgact tcgatgactt gttcgatgcc gattgttttt aacttatgga
    13681 tactctcata gaaacgaaca ggttgcatga cttgctgttc aagtagtccc gcgattgttt
    13741 ctttcttcat tatttccgtt gttgtgttgc ttatgatagg aaaagaaggt tcagagaatt
    13801 gaatctgact taggtccttc gccagttttt ttgctgccgg ttctaaaata gctgtatgaa
    13861 aaggcccgct gacatttaga gggatcattc ttttgaaccc tttttctttt aatagtaaaa
    13921 cagcttcgtc tactgctttt tcttcgccac caatcacgat ctgctgaggt gtattataat
    13981 ttgcaggaga tacgatgccg tacttgctag cttcatgaca gctttcctcg atcgtttcaa
    14041 tcggcgcatt catcactgca accattttcc cgcttccggc tggggcagct tctgtcatat
    14101 aagcgcctct ttttgctact aacgcaactg cttcagtgaa ggatagcgca ttactagcta
    14161 ctaatgccga atattctcct aaactcagtc ctaaagctgc atctgggatg attccatgct
    14221 ccttcaataa gcgataatac gcgatgctga ctgttagaat agctggctgt gtatattgcg
    14281 tctgatccaa acgttcattt tctgtaaagc aaagttcagc catatcgtag ccgagaatct
    14341 cacttgcttc atcaaatgtc tgctttacaa cggcttcttc atataaatct tttcccatac
    14401 cttgatattg tgcaccttgg ccactaaata agaatgctgt tttcatgttt ttctccaata
    14461 tatccagaat atatgtttga ttcttcctat tcaaaaaggc cgagacattc ctatttcagg
    14521 aaatgtccca gcccccaacc taattttaat gattatgcag tttgtttttc tacgtaagtc
    14581 actaaatctt gaaccgtttt gattccgtct tctgtttcga ttttcacgtc aaattcatct
    14641 tcaatttcat tgatgatttg gaataaatcc aagctgtcag cttctaagtc ttcttggatg
    14701 tcagtagtca atttgatttc ttcagtttct tttcctaatt cttctgcgat gatttcttga
    14761 attttttcga ataccataat aatatattcc tccgatattg tttgcttttt atttttataa
    14821 tttaacagtc tacaactcca tgagaatact tccccatgtt aaacctccgc catagcctgt
    14881 aaatattact ttctgctgtt ttcctaaggt gatctttcca ctagaaactg cttcatccaa
    14941 taagataggg atgcttgcag cagatgtatt cccatattta tccatattgg tcaggaactt
    15001 ttcttgcggc atctttactt ttcgggcaat tttctcaata attctgaggt ttgcctgatg
    15061 caaaagcaga taatcaactg gtttgtcttt catgacttct tggatattgt ttgcaacgtc
    15121 tcgtacggca aaatcaaaaa tatctctgcc agtcatttgc aaataatacg aaccttctga
    15181 atcttctgaa tagaacggat ttttattttg ctggtagcca gcggtcaatg agctacttct
    15241 ggtaccgtca gctgctaatt tttctttcag caattttttc tgtggattcg cttctaagag
    15301 aatcccacct gctccatcgc caaacaacac agcagtcgta cgatcagacc aatcgattag
    15361 cttagatagt gtttcaccac caatcaccag tcccttagtt gagccgcagc ggatcatttt
    15421 ttcagccatg cttaacgcat aaacaaatcc tgagcacgca gcactgatat caaaagcgat
    15481 agcatgagtt gctcccaatt tcccttgtac ttgtgctgct acagatggtg tcgtgtaatc
    15541 gggcgacatt gttgctacta aaataaaatc caaatcttta gggtttagat ttttctgttt
    15601 tatcaatttt tccgccacta aaatgcataa atcagaagtc tcctgatttg ttacacatct
    15661 tcgttcacga atacccgtcc ttgacgaaat ccattcatca gaggtatcca tcatcttgga
    15721 aagatcatta ttagtaataa tcttttcagg aaggacgctg gctgttgcag taatcattcc
    15781 aaattgttcc attaaatatc ctcacttata gtcttgcaag aagtcgtgca agtttttcag
    15841 tgcatccagc aaggcatgct gttcctccgt agccattccg tctaagatgt tcttgaccat
    15901 ttcacgatga aaatgctgat ggacccgaaa tagtaacttt ccttttttcg ttagtcccaa
    15961 ctttacaacg cggcggtcat cttcactgcg gatacgttcg acatagcctt tttttactaa
    16021 cttgttaata gcagtggtca aggtcccaac agtaattgat agttctttgg ctacttctga
    16081 agttgttttt ttcttgtaca tcccgattgc ctcgatcgtg tgcatctctg tgattgacag
    16141 atctttgaat tgagattttt tcagctcaga ctcttcgatt gtcaaaatat cattgaagac
    16201 actaacaaga taatcattta ctgtttttaa atctggttcc atgttccacc gtccactaat
    16261 tagtttgatt atcaaatctt ttgatgttca aactatatct taactttttt caaaatgcaa
    16321 ccttaaaaga tcattttttt actatatgag ctttttttaa gattttactc atttaaaaca
    16381 actgataaat cagcatttat aat
//
LOCUS       DAFLWC010000067        16309 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.068, whole genome shotgun sequence.
ACCESSION   DAFLWC010000067 DAFLWC010000000
VERSION     DAFLWC010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16309
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.068"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..1835)
                     /locus_tag="L1V17_002063"
     CDS             complement(<1..1835)
                     /locus_tag="L1V17_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBN1236816.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWR"
     gene            complement(1832..2536)
                     /locus_tag="L1V17_002064"
     CDS             complement(1832..2536)
                     /locus_tag="L1V17_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBN1236817.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            complement(2548..4857)
                     /locus_tag="L1V17_002065"
     CDS             complement(2548..4857)
                     /locus_tag="L1V17_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBN1236818.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGEVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            complement(5052..5516)
                     /locus_tag="L1V17_002066"
     CDS             complement(5052..5516)
                     /locus_tag="L1V17_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236819.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            complement(5516..6142)
                     /locus_tag="L1V17_002067"
     CDS             complement(5516..6142)
                     /locus_tag="L1V17_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBN1236820.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            complement(6149..6514)
                     /locus_tag="L1V17_002068"
     CDS             complement(6149..6514)
                     /locus_tag="L1V17_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBN1236821.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            complement(6504..6842)
                     /locus_tag="L1V17_002069"
     CDS             complement(6504..6842)
                     /locus_tag="L1V17_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236822.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            complement(6832..7158)
                     /locus_tag="L1V17_002070"
     CDS             complement(6832..7158)
                     /locus_tag="L1V17_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBN1236823.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            complement(7139..7417)
                     /locus_tag="L1V17_002071"
     CDS             complement(7139..7417)
                     /locus_tag="L1V17_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBN1236824.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETD"
     gene            complement(7419..8783)
                     /locus_tag="L1V17_002072"
     CDS             complement(7419..8783)
                     /locus_tag="L1V17_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBN1236825.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            complement(8796..9365)
                     /locus_tag="L1V17_002073"
     CDS             complement(8796..9365)
                     /locus_tag="L1V17_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HBN1236826.1"
                     /translation="MKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWDDL
                     SEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDTTV
                     ARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYEDTE
                     AALRSRDELEKNVEERKKLIKKINQALEA"
     gene            complement(9337..10524)
                     /locus_tag="L1V17_002074"
     CDS             complement(9337..10524)
                     /locus_tag="L1V17_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBN1236827.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            complement(10588..12315)
                     /locus_tag="L1V17_002075"
     CDS             complement(10588..12315)
                     /locus_tag="L1V17_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBN1236828.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            complement(12312..12764)
                     /locus_tag="L1V17_002076"
     CDS             complement(12312..12764)
                     /locus_tag="L1V17_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HBN1236829.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            complement(12876..13256)
                     /locus_tag="L1V17_002077"
     CDS             complement(12876..13256)
                     /locus_tag="L1V17_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBN1236830.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            complement(13253..13639)
                     /locus_tag="L1V17_002078"
     CDS             complement(13253..13639)
                     /locus_tag="L1V17_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236831.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            complement(13641..13919)
                     /locus_tag="L1V17_002079"
     CDS             complement(13641..13919)
                     /locus_tag="L1V17_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236832.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            13967..14695
                     /locus_tag="L1V17_002080"
     CDS             13967..14695
                     /locus_tag="L1V17_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HBN1236833.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            complement(14826..15302)
                     /locus_tag="L1V17_002081"
     CDS             complement(14826..15302)
                     /locus_tag="L1V17_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HBN1236834.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(15262..15609)
                     /locus_tag="L1V17_002082"
     CDS             complement(15262..15609)
                     /locus_tag="L1V17_002082"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236835.1"
                     /translation="MNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVLKIE
                     QNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIRGGV
                     CEISLVKRLPRTR"
     gene            complement(15596..15781)
                     /locus_tag="L1V17_002083"
     CDS             complement(15596..15781)
                     /locus_tag="L1V17_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236836.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            complement(15782..16054)
                     /locus_tag="L1V17_002084"
     CDS             complement(15782..16054)
                     /locus_tag="L1V17_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HBN1236837.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            complement(16051..16254)
                     /locus_tag="L1V17_002085"
     CDS             complement(16051..16254)
                     /locus_tag="L1V17_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236838.1"
                     /translation="MVKVREQFKIVSDEGNVYKIKIVNINEYREADHKYLVDLYMNDK
                     YLGEGFCGDSLFDDERILKEETE"
BASE COUNT         4566 a         3451 c         2536 g         5756 t
ORIGIN      
        1 attctccaag ctctcttttc tgcatctgtt tttaattcat caggataccc accaggtgtt
       61 tctcctccgc cagatggacc gccattttgt cctggtatca cttctttacc tctaacagta
      121 agttttccct gaatatctaa atcaccgaaa taatatgctt ttccgtttcc taataacaca
      181 aatccttttt ctgcagttgg agaaattaaa atgtattttc catcgccatt tgtacgtatt
      241 accaaagaat tttcctcaag aggtgtaggt gttacagcat ttggaaatgg atttcctgct
      301 gaatctgttg ttccgatcgt tccaatggat tcttttctat tccagaattc catacctttt
      361 ttggttagct ccatgatttt tttgttttca ttccaaattt gaagcgtgcc ttttacaagt
      421 tttaacacat caccataagc attaaaggaa gtttcgaata cttctgcatt tattgttcct
      481 actttgatga agtcagcaac aatttctcct tttgatgtga tagcaatacc gaacgggcca
      541 tttactccgt tgtctgaata acctaagcca tttaaattcc aacgccacac tcgctttgca
      601 ttcgccacat ttggagtatc catgataaga atctctgatg gagctttttc tggacgaaaa
      661 acgacatgcc caccagaatt accagtgatc catgccgtcg cattcaacac attttgaact
      721 aacgtttctg ttcgattgtc gattttcttt ttcaattctt gtgcttgagt atttactgcc
      781 gaagtgtaca gtgataaatc attacctaaa acaatatcct tatatttccc aagcgttggg
      841 aaataagtgt attcgaccat acgctctttt atctcgatat ctagctcttt cgccctaaca
      901 tgagcgacat caccaaagtg taaagacgct agctcttgat acatgtcacc gtattcgagt
      961 gtgtgttcca acgccaccat actgactgta tgagtagctt ttggctcatg gatacgatca
     1021 ttgtcaaata aggttttgcc ccatttgatc aattcatcaa ctgttttaca atctccgttt
     1081 tcacgtttgg caatacgtcg attctcgttg gttactccat caatttctaa ataaccatat
     1141 tcgataggtt ctttgtcttc atcataatcg ttatcaggaa caccgccaac caaatacaaa
     1201 ctattgacaa ttgattcttc atcaatttct tcttcgattg cttctaaatt gatgccaaaa
     1261 tcaatccgaa aaccattatc tgatccaatc tgttttacca gtttcaaatc atagttatcc
     1321 atatcaagtt ccgcgctagt cacgccagtc aaattttgat taccgttatt tgaaccaatg
     1381 attgcttcaa ctggcgcgac ttgtcttgct gtaaattggt gcgttgtccc tacattcgaa
     1441 agatagttaa atttttgatc aaatgccaaa ctgtttttaa gattggtcat gatctgagac
     1501 ccattgccgt tatccgtaaa cgacttgaca ataaagttct tattggccat aaaaccaata
     1561 tgccgagctg ttacagaaac ggaggtcaaa ttctttttga cattataaat ttcaaaatat
     1621 tgccatgatc catctggtac cttcgctttt ataaaatttc ctttttttaa ataagagcga
     1681 tactgtccgc ttcttgaata gttaccataa aaacgatatt ggccattcag cacacgattg
     1741 atttctggca aatcttccca atcaactaac gacgctccgt tcacgctcaa atcatctggc
     1801 atttttttat aagcataaat aaattcttgc gtcacagata cacactccta ttccaaaacc
     1861 gcacttcttt aaattttccg gatattttta cctgattcca ttcaggctgc aatactggcc
     1921 aatcaccacg cgtaaataaa ttcaaacctt cttgtattgc ttttccaagc tgagtatcaa
     1981 ccacgattgt tgcagctaac gtattaagta ttgttaggct tttatcaccg acagcgatcg
     2041 ttatatctcc tccgttcgat tctatttcca gatagggatg tgcaatttcg tcaccatgat
     2101 caaaaatatc cataacacta gaatgaaaaa ttttaggtgc ttcaccgatt tttcttttga
     2161 gtggctgaca acgaaaagta acatcgaatg tataaaagaa gccccactcg ttttcgaaag
     2221 ggacttcttt atccatgctg cagatagcct ctagatactt gtctggatca ttatgtgtga
     2281 ttaattggct tttaccagtg agccatcgtt tgacttctct cagtttcgaa tgtggaatag
     2341 tgatcccttc tatttccaaa tcaaaaggtt catagtcatc aaacgtctcc gtcaattctc
     2401 cgcttcggcc ctgaatcgtg taagtttcgt atcgcttgtt cggcataata tctggaagct
     2461 ctgcctcaat gatgcaattc atatcaatta ctgcattccg atttttccaa ataaaatttg
     2521 gttcatctgg attcataaat tgtcgactca aataggaaca cctcccaaat cacgaatagc
     2581 ctgtttgttt gctttagcaa atttacgatt catacgatct aactcagatg gattgtttgc
     2641 atcgactttg ccaatgtgta tatgctgttc aatgctacct ccagaaactc ttccactgat
     2701 ccctttgcgt ttttcttcgt ctgataatgg agtaactgtg gttttaccat tcttggcagt
     2761 cagtaactca ggtccagctt caccaacaat cgcttgtcca ttgattagat gaccgccttg
     2821 tgctaaataa ggcagttttg aaatagaaaa tgattttcca cctacaccag gaacccattt
     2881 tggtatcttt atattattca atccaccaat aaatccattg atcaatccaa tcatggcatt
     2941 aataggagct ttccctacag caacaatacc atcgaaaata cctccaaaaa tatcaactag
     3001 accttgccat gcttttgacc aattccctgt aaatactcca gtgataaaat ctagaaaacc
     3061 actgaaaatt cgttttccag cattataaaa attattgaaa tttgctataa caccatcgaa
     3121 aaatccacca aaataaccac ttaaaaaatt aaatatttca acagctacat ctgaaacacc
     3181 tttgaagaaa gaattcactc catcatgaaa ccatttaacg ttattatatg cccaaattag
     3241 tccagtaact aatgcgccaa tagctataac tgctaatgca aaccagcctc ccgacattcc
     3301 aaataaacca gcaagtcctt gccaaactcc tataaaactt ttaacttccc caacgatttt
     3361 tgtaacagat cccataagtg aaccaagaac gattagtact ggtccaactg ctgccgctat
     3421 accagcaatt gttatgatcc aattctttgt atcttgatct agagaccccc accatttaga
     3481 gaattcctgt aataaggaag ttgctttttc aaaaaaaggc aaaaggctta cttggactgc
     3541 ttcacctacg tcagccattg ctaattttgc attgttcata gcttgatcgg cttgatcaat
     3601 tgggtcgaga gtagcatcga atgtgtctcc tacagctccc ccactttctc cagcagtttt
     3661 tgctaaatct tccaggttca aagtacctct acgaattgca tcggccattc taggaccgcc
     3721 tttagtcccg aatacttctg ctgctgcatt gatggcttct gtttcagaac ctgcattttt
     3781 taccttgtct tgtagttctt ctagtccttg acttaaagat tttccgtctt tcgcataagc
     3841 cactgttgct ttagataaac tacttaaagc tgcgcttgaa tcaacaccag attgctcaaa
     3901 ttgtccaagt aaagtgaccc cttcaccaaa gctcaaccct aattgtttaa tttgtggtgc
     3961 gccatcaatt gctttttgca tcaagtcgtc tacagattga ccagtattct gcgatgtttt
     4021 cgttgttaca tcaaggacag aattcaaatc atcatattct agtccataag catcaatagc
     4081 ttgtcgagca gatattgctg attgcgaaac atctgtatca ttgatttcag cgtactgtag
     4141 gagataattg gttgaatctt ccagtttttt atccatgaat ccaaattgtg tatttacctc
     4201 accaatagct tccccaaccg tttgtaaagg taaatgagta tttgaaccaa cgtttttgaa
     4261 agactgtgaa agtctatcag cttgatcacc tgttgctccg gtttttgtaa tgatggtatc
     4321 aagtgcctcg tcaacttcac caaatgctgc aagtcctgct gctcctgccg ctacaatagg
     4381 cgcggttact ccaacagaca ttttttcacc aacgcctttt actttctcac ctgtttcttc
     4441 gattttctgg agtttttttg ctgtatcaac agaaacgtca ccttgttctt taagtgcatc
     4501 gttcgtctgt tctaatgctg tacgaagttt attttctccg gtttcagaat tgagtaattg
     4561 tttataaagt ttttctgatt cagcagaata ttcaccggtt tctttgacag atttttcata
     4621 ttcctctctc agcatttgag atcgttgttc agccaatcct aattgttttt ctaatttttg
     4681 tttagccgct cgcaattttt ctgtttgagt tgcatccttg tccatcgcag acacttggtt
     4741 tttgtactcg gcagcggcta agttcatttc tttgttgatt tctttgattg ttttcgaata
     4801 actgacttcg ccattcgttt taaaattaag aacgacatca gattctttac cagccattta
     4861 tcttagcgct cctttctacc accaaggcga tttatccata gttacagatt gaggtggttc
     4921 aaaatcggtg ttttgttgta accactgtaa ataagatttg agccacaagt taggtgtaga
     4981 ctttaaaaag aaactctcac tccaattcaa tagagtgaga gcaacgtaaa tataaaaact
     5041 ccaaggagtt cctatctctt ccgattcttt ttgtttttct ttctttttgc ttgcgctttt
     5101 tgaaagtctt gtggcttctt ggattttttt aggtcttcca cctgaaatgt ctggctagca
     5161 aaaatttcca tacaggtact ataagcagac aacacctctc cactcattcc caaaaatttg
     5221 aaaatagttt ctggatcttc ctctaaacca ccagtacgca gcatggcata aatcaaggca
     5281 cgcatgattt ttagatcact aggcgataag ttagcagaag aaatttgtcc ttctttttta
     5341 gatagcatgg cgttcatatc agattcaaat tgcgaataat ctccaccata cacatctgct
     5401 ataaattcca tcgtttgcat agtaaatgaa atagggaatt ctgcgccttg aataattaca
     5461 acagcagaat tttttaagtc ttcaacgtga attccataat cagataaccg agccattaac
     5521 ccgcacctcc aactttagcc aatgttttcc actgttcttc atcgtataca ggttgagcaa
     5581 tgaatttatt aaataattct agagaagctc cgtctctatt tgaatcaaaa cttgcataca
     5641 tcacattatt gtatttcagt ccgatggaaa ccagatttgc agttacatcg tcaatttttg
     5701 tttcttcctc tgcagtggca tactcttcgt caatcacatt ggatagttgt gtattaggat
     5761 accaaactgc ttttttaccg ccattttcaa tatttccaat aaatccaaag gcgaagtacg
     5821 gaaattctcg tgcggtattt ttgctaaacg ttactccgct tttagcaact aatcctttga
     5881 tttcatccat cacttctatc ggaataccca cgtgatccaa cgcaagttca tgttttgttt
     5941 ctcgcgacac acgacgaaac attttgctgg atgcccattt ttctaatgct gttccattcc
     6001 ctttgacacc gatttttgtg gcaattggca atcgtaaaac ttcactataa gtcggtgcag
     6061 ttccaacaga atctggcgtt gccatcatcg caattaaaat gtcgtccaat ccttcaaaat
     6121 aaaaagtatc ttgttttccc aattaaaatc acccttccca taaatcaagt atttttctag
     6181 tcataatttc ttcaattttt tctttgtttt gttcatacgt accacttgca aaatgttggg
     6241 cacgttgatt tgttgtgcca ttttcggcaa agcgccagta aaaggccgtc tcttcaaatt
     6301 gaactttcac ttgatcgttt tcaactacta cttttatttg atcgcgcata tgtttctttt
     6361 ttaagagcga cttaggaata ttaggaagca actgctttag ataaaagtta gctgcttctt
     6421 ctaaagattc caacgataat tttttcggat caacttttga aaggtttcct aaataatccg
     6481 atatttcaga aaaaccattc ttattacttg gcattttcca cacacctcac atatgtgtaa
     6541 tagttggtta cggtatcgtc gttctcatca ccttgtatac ctgtaaaatc tgaatatgga
     6601 atgccagcat tttgcagcgc ttgttcaata acaactaaat cctgttctgt tccaagtgta
     6661 aaaaaagaga cttggtaata aggtaatttt ttatagactt taccggatgc catttttttg
     6721 ctgttactca catttgagta cacaatgtat ggatacatcg tccctaatct ggctttgtct
     6781 ctgaacactg ctaactttgt tgatttcagc gctgttttca attcatcaaa gctaatcgac
     6841 ataagctaaa ctcaactcca tttctcttgc atcgggattc gtataaatgc gagtaatgtt
     6901 atacgttaca gaatcaattt tgagcgcact taatttctct gtgatggatt tatcccatct
     6961 gactttaatt cgtctgacaa cgtctgtctt ggcttgctgt gataaatatt tttcttgaga
     7021 agtcacaccg agttcttcat agaatattag acgcttaaat tcgtaaattg tagttggacg
     7081 atcgtttccg tctgttcctg ttttgatgtc tagcaattcg gctttccatc tgagattatt
     7141 agtctgtctc ttcggcattt tgaatcgctc cttgcacgat aaatggcgtc atggcattca
     7201 tagctttgtc gagttcatcc tctgaaactc tatattcata ggcaatgccg gcaaccatca
     7261 aaataagata ttcttgttgg ccaccagttg ctgttttgac ataatctttt gccatattta
     7321 aataaaaaga gagcaaagaa tcatccatgc cctcttcaaa atgaatatgt gatttgaatt
     7381 tttcctctaa agacaattct ttagtttgct cttccatctt aaccaccaac tggttttgta
     7441 atttcgtagc gatatactgc cggttcaaat ggagaataaa ccaattgacc atctagcaag
     7501 ttgtaaattt ggaatccaat ttgattttta ccagagaatt tttcaacaag tttttgaatt
     7561 tccaaggcac caataacttc ttgaatttta aatgcagaaa aatcgccaaa atataaaact
     7621 ggcgtgtctg gttcaccctt tttatctgct gcatctgtcc aatccacagg atagccaact
     7681 aattggtaac caattccacc ttctgcttgt gtgaatggcc gcaacaaagg aaatccatca
     7741 tctgttttca ttttttcaat ggcagtcaaa gcagctcgat taataataaa gcgtcccttt
     7801 ttcatcactt ctgtcactgg tgtattttta aattcgatta atgcatcata taatttttgc
     7861 ccagcacctg aagcagttag atctaaaggt tttttaaatg ctacagcctt tttggctaat
     7921 gcaccaggat tttcatttcc agcgtcatca ccattgaaca tataattgat ttctttacgc
     7981 acataagctt ttttcaattc ttccacaaca atatcttcaa ctggaacacc agacattttt
     8041 aataattttt tagttactgt tgccaaagca tcgaattcgg caggattaag caaaatttca
     8101 tcaaactgaa tagctgtttc agcaatatca gttgaacgct ctttcttgtt tacattcgca
     8161 tctgctttct tcacaagaat tggatatttg acatctcctg atgttcgcac cactgttccg
     8221 tatttacgaa gtaaattttc ttcttgagca taagtaataa cttcagatgc aattacttct
     8281 gggacagtaa ctgaaccgtt gccagcttca atccctaaag ctcgagcttc tgcttcagaa
     8341 atatttccag ctacaaaatt agcaaatgct tttcgtagtt gttgatcttt ttgtttcttg
     8401 gtcatttttg cacgtgcctc caatccgttc ttaattgatc caagtaatcc atctcgttgc
     8461 tgttgagtaa tcattccaga acgattttct gaactatctt cactgtctga atcttcttct
     8521 tgatcgttgt cttcaccaga acggctttcg tctgaatccg tactattcga ttgatcatct
     8581 gtattgtcgt ctgtttcatc agttccagaa tctgcgccta attcgtcttt aattccgttc
     8641 aattcatcaa taacactgtc aatttcttct ttcacggctt ctaaatctgc ttcgcgtaat
     8701 tctcctgatt caactttttc acgtaattca gtcaatcgtt gctcacgacg tgccttcatt
     8761 tttttcaata attctttatc catgtatttt tcctcctacg cttctagcgc ttgattaatt
     8821 tttttgatta atttttttct ttcttcgacg tttttttcta attcatcacg acttcttaat
     8881 gcagcttctg tatcttcgta tgctggcaaa ggcacaatag aaacctcgta taattccact
     8941 tcatggattg ttcgaagcat tggttcagaa ttgtagtccc acgtttcttc agtcggcaca
     9001 aaaccaaaac tacattggtt gatgtctcct cgttccatag atttaactaa gtcccttgct
     9061 accgttgtgt ccggtaaatc aacttcgaat ttcaaaccac gttcatcttc ttcaaggcga
     9121 agggttccgc ttttagtacg tcctagcaca ttggaccaat cgtgattgaa caaacaacga
     9181 acatccgaat tactaattgc ctttgagaat gcaccaggaa caatcacttc gcttaagtca
     9241 tcccataaaa gtgtttgact gttgaataca gcagcgtagc cgctaatggt cctcgtatga
     9301 gtttcttcat cggaacgtgt tgaaagattg gtgatgtcaa tcgtgcgaat ttccttcttc
     9361 ttcatttcca tcacctcctt tcaagtcttg atcattcgtt ggtaaggaat catctgttgc
     9421 atttttctgg ccaatcctag ataagtcatt tgaaatatag atagcttgtg tttctggagt
     9481 attctgttta ggaaaaccaa gcatttctgc cacgttatct ggacttgtaa tcccggtacg
     9541 aacgatgttg tagccaatat ttgtttttgt tgagtaagga acaaaatcca aaatattaat
     9601 tttccattcc actctatagc cagaattagg cataaaaaaa agagcggtgt aatgttcgct
     9661 cttgtttttc aatattggtt tgattgcttt gttgtgcaga tacatcatcg ctttttcaat
     9721 atctgtcttc atcagcgatt gatacgtatc aacattgatt cctagaaatt ttcctaagtc
     9781 ttttttgtaa acacctaaat aattcaaaat tgccgcgtca tcaacaggac tttttaatgt
     9841 ctcgatggaa tatccttttc ccaaaggaat catcttaaca gaatgatcac tctcattttg
     9901 cgttccttcc agttgatcca atatagcttt gacaattttt gtttgggcgc tattatttgg
     9961 attgatgtgg gcgtctagtt taagcatgaa cgcaagtaaa ccgcctttag tatatttgtc
    10021 cgtcaaaact ttttcagcgc tcagaacgcc ttctagagtg tttcttgcaa gatcaattat
    10081 tccagcacct tttaatgaat cagttccgat gttcttaatg tgtcgaatca tttgaccagg
    10141 tattttttga ccattcattt caaattcttc ttgaagtcgt tcattgattt tagttgttac
    10201 accgtacgcc aaatgaagct gatccctatc cgttaatggg aatgtctcac cattgatcaa
    10261 taaagtattt gtttccaatt tggtaaattc gaatcctgtc aaataatcat tgggactctt
    10321 caaaatattt agtaagtgat gatctttgac ttcgttgccg tcgggaccaa taacaattgg
    10381 tgtggccaat gccacctgat tagatatgtc ttgaactaat tcataaacat cagaagattc
    10441 catgatagat gaatccgtca catatctttg accataacgt gtgtagtgtc caaaaatatc
    10501 ctcgatatat ccacgttttt ccataaaaga atagactgca ttcgataacc gatcacgtaa
    10561 tttcaatttt tttcaccgcc tttctattta tctatagatg gaacttaggt aatcatctaa
    10621 ctcatctgaa tcaatatctg tcatttgatt catcgtttcc ttatgaccac acaaaaacgc
    10681 cacgaaccca tcaatctttt tctttgattg acgtttactt ggcgcttttt gtccattgat
    10741 gttagtaatt gctacaacgt tcaaagtgca ataaaggaat aatggattat caaattgaat
    10801 tcgtttctca taaaacaacc gttcgacatc gtcaaaagga gcattcaata ctttaggata
    10861 ttgagcaact tcaacgcatt ccaatcctaa gttttctaat ttctcaacaa gtttgtcact
    10921 catcgctgga tcataattca cttgctgaat atcatataaa ttcatgcagt cctctatgta
    10981 ctgcaaaatc tgatcttgat caatcatttt tccgtcgcaa aattcaacga aaccttgttc
    11041 agccaaatca ctgtaaggaa cattatcttc tttttctcga aactctaaat cttcattcgg
    11101 aataaaataa agttgcttta ctttaagaac cgctttacca tcttcatccc atgttgggaa
    11161 gtttaaagat acacaggtca aatctcgtgt acgtgataaa tctaaaccga tataacatgg
    11221 ttcgccactt aaatcaccaa gttcttgtgt ggtaactaaa catggctcta cttgatcctg
    11281 ttcaaagaaa ttatccgcgc cgttcacaaa tacatccaag tgtttcgtta gaaattcagc
    11341 tttggaatga gctgaccgtt gcgctgtttt aaatgccgat tctaaagcag ataaatcgac
    11401 tgatattccc cagttaggat tgcacatttc ccagactttt ctatccgtcc aatcataatt
    11461 tttatttggc tcatagatta gaacaaagtt tgaatcatta tcatcacgtt tcaacacttc
    11521 ttttgcttcg cgatatacac gcattccaac agacgacgaa cctttcccag cagttgagat
    11581 attaaacatc aatggctgtg gtaaagatat ctgagcagac ttaaaattgt catactgttc
    11641 cattttctcc tgtttatgca attcatcgtt caatacaaaa tatggattgg atccctcgat
    11701 attatcaata ttcttggttt gaacaataaa tttatttgag taagccatat cttcatgaat
    11761 atagtcataa gtaatactag aaacagttcc ctttggcccc ctaaatattt tagttccttc
    11821 aagtaggatt ggattgttta agattgtaac tgcaaaaggt ttggcagcat attgcgcttg
    11881 agcaaaatca gatgcgcaag catagcaatc aactgataac gccccttctc cgtacattgc
    11941 atatcctaat gaaccgacag caatcaatgt tttaccattc ttttttggaa tctggacata
    12001 agcctcacga gtaacgcgta caatttggcc tttttcattt tctttaaccc aaccataaat
    12061 ccaagaataa ataaattttt cccagggttc taaaagaaac ggttttccca ccatttctcc
    12121 ttttgtgtga acaataaatg attctaccca atccatcatt tcattcgcgc gatctacatc
    12181 aaaccaaata tcttttcttt ttttccactg ataccagcga tctattgcta aacgaacggt
    12241 cttaggatac ttcttaggtt tctttcttac ttcttttgca aataaatcag cataatttac
    12301 accaggttca atcatttttc agcacctgcc ttcttacgcc atttatttct gtgcgctgct
    12361 agttcatcta ctggctttac ttctgggcgt gtaatttctt catcttttct tgcggtcgat
    12421 cctccagcaa ttagtctacc agtttttgct ttgtttgtta atcctaataa atctagagct
    12481 ttcatcttct tatctgccca agtttctact tgttgtgcca atggatgttt tgattgatta
    12541 gtagctcctg atttattcgt gaatttttgc gtctccggaa atcctttttc cttccacaat
    12601 aaatatttgt gttggtaaat ttcaaaaata tccaagtatg attcgattaa tggatcaaga
    12661 gtgatggtgt acaaatcaga caaattcatt atttctaaga tacgagcttt ttcagcactt
    12721 actttttcat caataatcgc tttacgttgc gctttagtcg tcatttttgt atacaccccc
    12781 ctttgttttt tgaaaaattt gacctaacga tgcgcgtgac tccccgctac cctatctccc
    12841 cacgcgaaaa aattttgaaa atgaataggg gggcttcaat tgaaatacga aggaaaaact
    12901 tttttgtctt ccgtttcgtt ttcaacaatt ggatgacatt ttgaacataa tagcatgaga
    12961 ttgtttggat caagcttaag cagttcgttg tctttgattg gtacaatgtg atggacgtgt
    13021 gctctctttc caaatatgaa ctgaccacac cgctgacaat gaccaccttc tctttcataa
    13081 ataaattgac gcatatcttt ccatgcttgc gttcgataga atggtttgtt ctcatgatga
    13141 taaacagact ttgcttgctg cttcttcttg cgtgatctgc ttgatctctt gtgttcagta
    13201 cagtagatac cctttgctat tttgttcgtg catccgtcaa actgacagta tttcattcta
    13261 cttcacgaat aagatttatg atatcgcctt ttgcacggat agcaccagga atatcaatac
    13321 catgtttctt agcatatgca cgcaattctt ttgcagtcat attgtccagt tcatccgtat
    13381 cttcagtgga ctgatcatta gtagcttcgt ctccatcaaa attagcagca gtgtttccat
    13441 cgctatcaag aatttcactg ctatgagcta tgagttcgcc attgacagca acaaatgatt
    13501 tgccatcact caaaattcct ttttcttctt ttacttcaaa atttggttct tgatctttcg
    13561 gaacaactac tgtccttttc ttttctgaat cccaatactc tgttccacta atggatgttc
    13621 taattttgat cattgccatt ttaattctct cctttgtaat ttgtacggat tacttttgcg
    13681 cccattcgct cataccattc aatcgtttcc tgcagattgg gtagagtgtg tgacaataaa
    13741 gaaataacta acgtattcat tccagttctg taatcatcat tctccacttg cacatgtgca
    13801 tgattaccat tccaattttc tctgtacgga ctattctctg cttcaattgc tttcttataa
    13861 actttagcca aacttgattc tacttcaata ctaagtaccg cttcatgaaa atcattcatt
    13921 tgtttactct cctatcagat attttgtggt atgatttata aaaaagatgc gaggtgtttt
    13981 aatgcttcaa gaagttaata ttaagtatcg tgatcgtcaa aatacagaga caatttattt
    14041 gccaaatagt tgtccgcatt gcggaaatat aatgactccg tatgtgtatt ttggggtttc
    14101 atcatatagt gcgttcgata atgatagaat ctttggcgta ttagtacagt gtataaatga
    14161 tgagtgcaac aaattttata gtttacaatt tataaatacg tttaatgaag atgaaggata
    14221 ttctgaaaat attttaatta aagattatta ccgtccgccg attaaaatag atttaccaga
    14281 aaatattgaa aaagtttctc ctacatttgt tgatatttat actcaagcca cacaagctaa
    14341 atctgagcaa ttggaacaaa ttgctggagt tggttataga aaagctctag aatttctaat
    14401 taaagattat gcaatatcta aaaattcaga ggatgaagat aaaataaaaa aaatgttatt
    14461 aggtaaaaca attgaaaatt atttgaatga ttttcctaaa ctccaaagat tagccaaagc
    14521 tgctacttgg attggtaatg atgaaacgca ctatgttcgt agacatacta ataaagatgt
    14581 tcatgatatg gatgcattta ttaaatcagc agcgcaattt atcgcggctg attatgatgc
    14641 tgatttagct gatcaattta taaatggaaa taactttatg ccaactacta attaaaagaa
    14701 taaaagagcc acagatacca attaataaaa cggttgggat atcttggctc tttcatattt
    14761 ttttgacact aatagaatat catgctgcta acaatgttta cgaacattta gtgaacagtg
    14821 taattttaga ataaagagag ttgttctttg tacttctcgc tattgtaaaa atcaatttcg
    14881 ttttcttttt tcaatcggtc agcttgtctg tgttcatact catctaaaaa gttcaatgtc
    14941 tttctaattt ctgcatgtcg ctgtctgaca tacgatgagc tatacccaac agattcagca
    15001 atatcttcta agctcatttg atcaacatat ttcatcttaa caatttgatt atcgatacca
    15061 gaaaagctat ctatcagcaa taacatttct tctttttgct cgatcaacaa ttccaattca
    15121 ttttctatct tttggatatt ctcttctaaa gaagaagttc tcgaattctt ttcgatgcgg
    15181 acgtttgcta aatcaccaca gacccatcga ttcaattcaa gcttactttt attaagattc
    15241 cactttaagt aaagaatctg ctcatctagt tcttggtaat cttttaacca atgaaatctc
    15301 acaaacgcca ccccttatgg tagaatagta ttgcgctgct atctcgaaag gggtagcttt
    15361 tttatttttt cttagccgtt ccattctgga ttgccttttg ttccaaacgt cgttttttct
    15421 tcttaatctt tgattttgtt tttcccatac aattctcctt tccgaaaaca cattttgttc
    15481 gatttttaat actaaataaa agttggccag aatttttcgt tcgtctttac tcatcttttt
    15541 ttgaataaga ttactagcat aaaaatagtt agtaccacga aaatgaacag gtaaatcaat
    15601 tacgttcacc ttcttcatgc cagttatcag ccactagaat ctttgcgtta gtgccgccac
    15661 cgttttcttt tttgtatttt tcaaatgctt tataagcagc tgtttttgat ttatagattt
    15721 ttccggaacc gactgggaac atccatgtgc cctctgtgat agctaagatg tatactttca
    15781 tttaattcac ccctttaatc cccaacacta catatccgga cttctgcatg taatcagtaa
    15841 tataagtgat ctctgctttg tatgagtcac cagtgtaact aaatgttggt ctcgttagtc
    15901 caggtaattc atgtttaatg tattttttat attcacgtag tattaactga tcaccaactt
    15961 tgaagtcacg atcattcttg cggatctcga attgtttgcg tccgctcgtc actgcttcaa
    16021 aatattctgg tagtattttt agttcgtgga tcattctgtt tcctccttca aaattcgctc
    16081 atcatcaaaa agtgaatctc cacaaaatcc ttctcccaaa tatttatcgt tcatgtataa
    16141 gtcaaccaaa tatttgtgat ctgcttctcg atattcatta atattaacga tctttatttt
    16201 gtaaacatta ccttcgtcgc tcactatctt gaattgttct ctgactttca ccaccgttcc
    16261 tcctcttttt gaaaaaattt tagtgttttt gtaagacccc ctaaatcag
//
LOCUS       DAFLWC010000068        16030 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.069, whole genome shotgun sequence.
ACCESSION   DAFLWC010000068 DAFLWC010000000
VERSION     DAFLWC010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16030
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.069"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            88..606
                     /locus_tag="L1V17_002086"
     CDS             88..606
                     /locus_tag="L1V17_002086"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBN1236839.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            734..1417
                     /locus_tag="L1V17_002087"
     CDS             734..1417
                     /locus_tag="L1V17_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBN1236840.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1726..1799
                     /locus_tag="L1V17_002088"
     tRNA            1726..1799
                     /locus_tag="L1V17_002088"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1760..1762,aa:Arg,seq:tct)
     gene            1958..2317
                     /locus_tag="L1V17_002089"
     CDS             1958..2317
                     /locus_tag="L1V17_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HBN1236841.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2440..4071
                     /locus_tag="L1V17_002090"
     CDS             2440..4071
                     /locus_tag="L1V17_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HBN1236842.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQFPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4133..4774)
                     /locus_tag="L1V17_002091"
     CDS             complement(4133..4774)
                     /locus_tag="L1V17_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBN1236843.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    4960..5036
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            5056..5364
                     /gene="rplU"
                     /locus_tag="L1V17_002092"
     CDS             5056..5364
                     /gene="rplU"
                     /locus_tag="L1V17_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBN1236844.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5391..5735
                     /locus_tag="L1V17_002093"
     CDS             5391..5735
                     /locus_tag="L1V17_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBN1236845.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5748..6041
                     /gene="rpmA"
                     /locus_tag="L1V17_002094"
     CDS             5748..6041
                     /gene="rpmA"
                     /locus_tag="L1V17_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBN1236846.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            6475..9282
                     /locus_tag="L1V17_002095"
     CDS             6475..9282
                     /locus_tag="L1V17_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBN1236847.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            9473..9964
                     /locus_tag="L1V17_002096"
     CDS             9473..9964
                     /locus_tag="L1V17_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1236848.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            10067..11056
                     /gene="manX"
                     /locus_tag="L1V17_002097"
     CDS             10067..11056
                     /gene="manX"
                     /locus_tag="L1V17_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HBN1236849.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            11089..11892
                     /locus_tag="L1V17_002098"
     CDS             11089..11892
                     /locus_tag="L1V17_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HBN1236850.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            11913..12827
                     /locus_tag="L1V17_002099"
     CDS             11913..12827
                     /locus_tag="L1V17_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HBN1236851.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            12910..13284
                     /locus_tag="L1V17_002100"
     CDS             12910..13284
                     /locus_tag="L1V17_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HBN1236852.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGNNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            13423..13668
                     /locus_tag="L1V17_002101"
     CDS             13423..13668
                     /locus_tag="L1V17_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBN1236853.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            13840..14904
                     /locus_tag="L1V17_002102"
     CDS             13840..14904
                     /locus_tag="L1V17_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBN1236854.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            15150..15575
                     /locus_tag="L1V17_002103"
     CDS             15150..15575
                     /locus_tag="L1V17_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBN1236855.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            15568..16017
                     /gene="nusB"
                     /locus_tag="L1V17_002104"
     CDS             15568..16017
                     /gene="nusB"
                     /locus_tag="L1V17_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBN1236856.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
BASE COUNT         5135 a         2647 c         3495 g         4753 t
ORIGIN      
        1 gggaaacatt tttacagcta taatttgaaa aaatttatcg ttattatatg attaagaagg
       61 attgaataaa gaaagaagtt gaaaacgata cctgattaca aaaaaataac ttttataagt
      121 tctataacgt tgattatatt tttaattctt attcttctcg tcgtcttggt tccccgaatt
      181 tttggtttga ctccttatat tattgaggac aaagaaatga gtccatatta tgcacaagga
      241 aatctgatat atgtacgacc gaaaaataca aatgagattt tagtcggaga tattattaca
      301 tattatgaaa attcaggaaa aaaaatctcg acgcgtcgcg taatagccgt tgaaaacaac
      361 cacgaagatt tttatacaaa agctgataca aagacttata ttgagcctgg agtagtaaaa
      421 aagagaaata ttatcggtag tcccatcttt cagattccat atattggact agtcctttca
      481 aaaacggcat ttgcatggat tcaggggtta ttctttacga ttgctttttg cctaacagga
      541 atcacagcat ggaatacctt tgtagagttg aaaaagaagc ggagacgaac acagaaattt
      601 ttgtaagaat gttaaaaaca taaatgtatt ccagagatcc aacgactctt ctgaacatga
      661 aacacgagaa aacactcatg cagcttgtag atttagtcag ttgttcgtat aatgtgtgaa
      721 gaggaggagt agtatgcgca atgaaatgat gcatcgtcct gtagtcaaag aagaactatt
      781 ggattttatg cgtacccagc aaaaaaaatt accgggtgag ctaggcaaac tggaagaaga
      841 agctcatgta gcagaagtac cagttattcc ccatgaaaca gttgtatttt tgaaattttt
      901 acttggacag cttcagcctg aacgaatctt ggagatcgga gcagctatcg gtttttcatc
      961 aagtgtcatg gccacgacaa tcggagaaaa cgctcatgtt acgacaattg atcgtttcga
     1021 tgtcatgatc gagaaagcta aaaaaaacta tgaacgtcta ggactgacag ataaagtgac
     1081 tttgcttgaa ggtcaagcag cagatatctt gccggagttg tctggtccgt atgactttat
     1141 ttttatggat agtgcaaaat caaaatatat tgaattttta cctgaatgct tacgtttgtt
     1201 aagaaaaggt ggcgttttga tggtagatga catcttccaa ggaggaacga tcttgctccc
     1261 agatgaagag attccccgtg gcaaacgagc tatccatcgt aaattaaatg aatttcttcg
     1321 tgttgtgatg gatcatcccg atttgacatc gacaatcttg ccattaggtg atggtgtgat
     1381 cttaatgaca aaggaatcag aaacaatcga gttgtgatac atgattatgg cagcctgtag
     1441 ataatcgatt gaatcgaggg ctcaattcga acttgatgta aaagtttcta tatttgtaag
     1501 tcaattaaag gatacaggaa atctaaataa acaggagtag catgaagtca atgtagctcc
     1561 tgttttcaat tgataacctt agaacagctg aaggagaatg tctcgtttta aaagattgat
     1621 ttagtagttg ggccaaaata attcattatt tgctaattaa ataactattt cgtattgaca
     1681 gaagcaattt aattatctat aattattgat gttccgctga ttcttgtcat agtagctcag
     1741 ctggatagag catccgcctt ctaagcggac ggtcgggggt tcgaatccct cctgtgacgc
     1801 taaaaaaccg ttagaaactg aggtttctaa cggtttttct ttgttttttg tgccaatatt
     1861 gtttgttttc aaaggcaaat aaaataaaaa aacatcctta tcgagtacaa ttataaggag
     1921 caaaaaaata aaactcatca gaaaagagga agaagatatg acgatactat ctagaatttt
     1981 agtgactcta gttgcaattg aattttttta tatcatgtat atcgaaacgg tgagaactga
     2041 ttctgacacg acaagtaggg tttttaaaat gagtaaagaa gagttaagca gaaaatctgt
     2101 tcaaacattg tttaagaacc aaggagtgta caatggacta ttaggagtgg gactacttta
     2161 tggagcttat ctttcttccg catctaaaga aatcacaagt atgctattaa tatctatttt
     2221 ttttgttgca ttatatggca gtttgactag cgatcgttgg attttactca aacaaggtgg
     2281 gctagctctg ttggcattgc tttctatttt cttataaata tagaaaaaat aagaatttat
     2341 ctaacaggaa actttgtgaa aaatattact ttatctcatg aaatatgata ttctaatgaa
     2401 tggtatttta gaaaatttca tgaaaaagga gttagatagg tgttcaaaaa ttatgtttcc
     2461 tcactaaaaa aagaattttc aggttatgat ctttcaagat ttcagaaaga tcttttggct
     2521 gggatcacag tagctgctgt agcattgcct ttagccttgg cttttggggt atcaagcgga
     2581 gctgatgcgg ccgcaggttt gattacggct atcattgccg gtatcgttat tggcggttta
     2641 tcaggcggtt tttatcaaat atcaggtccg acaggtgcga tggcagctat cttgatgtct
     2701 attgcggcaa caaagggaat gcaaggtgta ttgcttgcta cttttttagc gggtctattt
     2761 ttacttgcag caggactttt ccgattagga acactgactt cttttatccc agcacccgta
     2821 attacggggt ttacttcagg tattgctatc attattgcat taggtcagat cgataattta
     2881 tttggtgttc actcggaagg tacaaacgtt attgaaaaac taagtagtta tcaaacgata
     2941 ggatttccga taaacacagc ctctttgatc atgggagggc tagtcatttt agggatgttt
     3001 atctatccaa aaaaatgggc gaaacgaatg cctagttcgc tgctggctat cattttggca
     3061 acagcagtta tgctattgtt ccatttacca gtagcaactg tgggtaagat tccacaaaca
     3121 ttgatcagta gtaatcgttt gaatatggga gattttagct tttctgcctt gcaacaagtg
     3181 gcagttccag ctattagcat tgctttatta ggaatgattg aaagcttgct atgtggtgct
     3241 tcggctggcc gaatggcaaa taagccctta gatagcaatc aagaattaat ggcgcaagga
     3301 attggaaatc tgttgcttcc tttctttggc gggattcctg ctactgcggc catcgcccgt
     3361 acaagcgtgg ccatcaaatc tggtgcacaa actagattag ctggtatgat acatgcagtt
     3421 gtcttactgc tctccatgct tgtttttgcg ccagtgatgt cacagtttcc aatgccagca
     3481 cttgcaggtg ttttgattgt gacggcttgg cgtatgaatg aatgggaaac gatcaaggag
     3541 ctatttacta ataaatattg gtcagcagtt ctattgttta tccttacgat gatttgtaca
     3601 gttatctttg atttaagtat tgctatcgtg atcggggtga tcggcggctg tgtatttttt
     3661 gttgtcaaaa gcgctgctat cacgatttca ttagaaacga tcgattggca aagaatgggg
     3721 ctgccagaaa cggaaaagct gaataactgg acagtagtgt atattagtgg tccactgttt
     3781 tttatgtctt cagaaaaact caaaaataaa ttggaagaac taaatcatca cgatggtgtc
     3841 attttctcca tgcgaggcgt accaagtatt gatttgacgg cacgtgcagt ttttgatgaa
     3901 tttcaagaaa aagcagagca aagaggacaa acgattatct atacttcctt gcagccagaa
     3961 gtagaaaaac aactttctca cttgtgggaa catacattca cgcatcaaca tcaaacagtt
     4021 gctcatgcgt tgacagcttt acatgcgaaa tatactgcaa ttagccatta aaacaatgaa
     4081 aaagaacaga caagactgta aactgaagat tttatggtct tgtctgttct ttttaatatt
     4141 gctgtaaaag tgaagctagt acttgccagt cttgatggat aacaggtaca agggagcgat
     4201 tgtagaaaat agctgctgga tgaaaaagtg gaagaattcg atagtttttt tctgaccatt
     4261 cgtaggcatc cttttgttct gttaattgta agacaggccc tgtatagagt tgaccatgat
     4321 ttttggtaac cgtatattct ttgccaagta aacgttgaag accaatgttt ccaagtgtcg
     4381 caattaattt tggctggacc ttcatcagtt cgtaatccaa tattggtgca tgcgcaaata
     4441 cttcggaacg agtaggtgtc cgatttggat aaacagtttc tgactgttgt gtccgtttat
     4501 tgatccgatg agtcacgcga tacgggcggc tccttacagc actggtgata tacacctctt
     4561 ctcgtgttaa gccagttgaa gaaagtgcct gcatcaattc ttttccagct tgaccgctaa
     4621 aaggaacatg cgtatcaatc tctgttttcc ctggggcttc tcccacgagc atcagtttag
     4681 gatgaagagg tccttgccca gcgataaatc cttctacagg acggccgttc attcttaaag
     4741 aagcttcttg tatcagttct tttgggtatt ccatttatgc tcctcctttt tcttttatta
     4801 taagaataaa agaaacacaa tgcgactatt ttatttggta gaactgtgag gatagaaaag
     4861 cagaagtatt gcttgaattt ttgttttact ttttgatttt aaatttagtt gactaacggt
     4921 tgctgttctg gtaagctagt actgttgtaa ttgtggactc cacagctaca accgctcaga
     4981 acaagtaata agcacagcat atgctgtcac ttcggatggc gagtctaagt atatcagaag
     5041 gaggtgcttt atagcatgta cgcaattatt aaaactggtg gtaaacaagt aaaagttgaa
     5101 gtgggacaag caatctatgt tgaaaaactt gacgttgaag caggagaaaa agttgttttt
     5161 gacgaagtta tcttagtagg cggagaatct acaaaagtag gcgctccaac tgttgcaggt
     5221 gcaactgttg aaggtactgt tgaaaaacac ggcaaacaaa agaaagtcgt tactttcaaa
     5281 tacaaaccta aaaaacattc acaccgtaaa caaggtcatc gtcaaccata tacaaaagtg
     5341 gttatcgacg cgatcaacgc ttaatagcgt ttgagaaaga aggcctatat atgatcaaag
     5401 gaacatttaa gcgaaatgac gcaggtcaga tcgtttcatt cactttgacc gggcatgctg
     5461 atgctggtcc ttatggaagt gatatcgttt gtgcgggtgt ttctgcgtta gcgatcagca
     5521 ctgtcaacgg gattgcctca ttagccggtt ttgagccgat tgttgaaatg aatgaagaag
     5581 aaggcggtta tctttatacc gaagtcactt caggaatgac acaagaacaa aacaatattg
     5641 ctgagattct attagaaaat cttttattag gattacaatc gatagaagct gaaaactcag
     5701 aatatatcca aattaaaaca attaatgata aataggaggt gcagaccatg ttgttatcta
     5761 tgaatctaca attatttgcc cacaaaaaag gtggcggttc tacatctaac ggccgtgact
     5821 cagaatcaaa acgtctaggt gctaaacgtg ctgatggaca aacagttaca ggtggatcaa
     5881 ttctttaccg tcaacgcggt acaaaaatct atccaggtgt aaacgtgggt atcggtggag
     5941 acgacacttt atttgcaaaa gttgatggcg tagtacgttt cgaacgtaaa ggccgtaaca
     6001 aaaaacaagt gtctgtttat ccagtagctc aagaagctta attgaatctt atgattaaag
     6061 aggttgtgac aagacttttg tcacagcctt ttttgtttat aaaaataaaa gttgtagtgg
     6121 aggctacgaa gtttactttg tctttttaca cttaatattt ttttgccaat ttggaatcag
     6181 gatgttttga taactatcgt tttcaattga tggaagctat attgtttgct atcagtgaaa
     6241 taattatatg gtaaacagtg ttctttttct tgtttccatt ataaaaatcg tatcgggatt
     6301 tttcgttctt ttaaattgaa catttctatc tatccgcgtg ttatcaacaa aacaaaatca
     6361 ggtaaatagt tgacgaaaca gaaataaata catagtatta tgttttgaag cctaagtaca
     6421 atagtctata gaaaaggagc gataccattg gcaaaacgca ttgaccgaat ttatatgtat
     6481 gtcaaagaaa aaaccgctca tttaacaaag gcagaatatg atcaaggagt aacaacacag
     6541 gaaattgctg aagtgttagg gattcagcga acaaatagca gtaaagatct gaatcagcta
     6601 gtgcgcgaag gaaaactgat aaagacagac ggacgaccag tacgttacat atatcaaaca
     6661 ctcgttacgc acgtaaagcc agttacaaaa catgtagtca gttacaaaga aacgccggtc
     6721 tctgaagaaa aaaatacact ccaaatagat actaaggata tctttgcaaa aatcattgga
     6781 gctaacggca gcatgaaaaa ttcagtggaa caggcaaaag ctgcgatttt gtatccgcca
     6841 agaggattaa attgtttgat tacaggacct accggatcag gaaagactta ttttgcacac
     6901 gcgatgtatc attttgcaaa agcgcatcat gtaatagatg aggaaacgga actgattgtt
     6961 ttcaattgtg ctgattatgc caataaccct gagcttttga tgagtcattt atttgggtac
     7021 gcaaaaggtg cttttacagg cgcagatgaa gaaaaaatgg ggattatcga tcaagcggat
     7081 ggcggtatgc tgtttttgga tgagattcac cggttgccgc ctgaaggtca agaaatgatc
     7141 ttttacttta tggatcatgg aacttacagt cgtcttgggg aaacaacgaa atcccatgaa
     7201 gcaaatgtac ggatcgtagg tgcgaccaca gaagacccag gttcttctct attagaaact
     7261 tttgttcggc gtatcccaat caatatcaaa cttccggctt ttgaaaaacg tcctgcaaat
     7321 gagaaagtcg atttagtaaa aatcatgatt gcccacgaag caaaccgcac gcagcgaaag
     7381 atttctttga cagaagatgt agcaaaagca ttgatcggca gtgtgaccta tggaaatata
     7441 ggacaattga agtcaaatat ccagttagta tgtgcacgag gatttctaaa tcatatgcaa
     7501 tcacccgaaa tctcgatcac aatcgatgat ttgacagaag ggattcgtag cggattgatt
     7561 caattagcaa gcaaccgcag tgcaatggca gagctttcta aaatattgga gccaaagata
     7621 actgtagcac caaatgatac gatcatgaaa atccaatcgg actcctatga gttaccttat
     7681 aatctatatg atatcatcgg agataaagca gctttactga agtcggatgg tttggatcaa
     7741 gaagcaatca atcatttcat ttctacagat atcaacatcc atctgaagtc tttctataaa
     7801 gaccatggtt tttcttttaa tgcagacagc aaattagcag aatttgtaga tccgaaaatc
     7861 atagaagtga ccaatcagat ttatgtaatg gtcaaaagat ctttaccata tgagtttcag
     7921 caaaacttta tttatgctat gagcttgcat atcagttctt ttttgaaaaa aatcaactta
     7981 ggagaagaac ggcatacgaa tgataacatc cgtgagatgg cttttgattt tccagatgaa
     8041 tatgctgttg cgaaagaagt gcgtagttat atcgaaacgt attttcaagt ggagattcca
     8101 gaaagtgaag actattactt gaccgttcta ctcgtctcgt tacgggcaaa tcaagcaagc
     8161 ggcagaatcg gtgtagtcgt tgcagctcac ggaaacagca cagcaagcag tatggtccaa
     8221 gttgtccaac agttgttaga tgcagagaac gtacgagcag tagacatgcc tttggatatg
     8281 gatccgaaaa cagcattgga ccgaattgaa cgcaatgtac aagaagtaga tgaaggaagc
     8341 ggggtcatac tcttagtaga tatggggtcc cttgcgtcgt ttaattcgca aattcaaaga
     8401 gacactggaa ttccagtacg tactgttgat atggtaacaa cttctctagt tttggaaact
     8461 gtacgaaagg tctcagtatt agggacagat ctagatatgt tgcatgaatc attgaaaaat
     8521 tttcgaggtt acgcagaaat atcttctgta gaatctgttc aggaagcaaa acctattcat
     8581 aagaaaaaag ctgttttggc tatctgcgca tctggcgaag gtacagcaca aagaatcaaa
     8641 gaattgatcg aacgagcggt aaacaagcgt caagaaacag aattagaagt tctagctttg
     8701 tcgattgtgg aagtgaaaga agaactgcca gttatccaaa aagaatatca gatcatagct
     8761 actactggga ttactgattt gaatatccaa gccccattta ttcctttaga acgttttatt
     8821 gatcaaaata tcgaagtcat tttggatcag ttgctgatgg aatcagaatt ggaggaaact
     8881 gaattcatct ccctagatga agagtcagct aaaaatacgt gtgttgagtt tatctctgat
     8941 aacttcatct ttattaatgg tagtaagtta atcgatccaa tgtggcaatt ttctacacaa
     9001 atctctcaga cgacgggaat cggcgatgaa gaatatggat tcaaaatcaa cctagtgatg
     9061 cacacagcag gaatgatcga acgtattatt cggaatgaac cattgactgt ggaagaaaac
     9121 gaattgacaa atacaacgaa tgatcctctt tatagccaat tggcagcctc agttgttctg
     9181 ttggaagatc agataaaagt aaaagtgccg atagaagaaa tgtattatct gctacgtcta
     9241 gtccataatc agttagataa aaaagaatac actgtgccat gaatacacaa aaacgataca
     9301 cttttatagt gtatcgtttt tgtgtattgg ttaagaatcc tttaaattca attagtgtat
     9361 cgtaaaaaag ttggcacgct ttttgcttat agtagtgtgt gctaggaggt ggttgttcac
     9421 acagaaatga taggggtttc tgtgaagtag tgaggaagaa ggagttttgc agatggatat
     9481 tcgattggca cgtatagatg atcgtttaat ccacgggcaa gtcgcaacag tttggtcgaa
     9541 gcaaacaggt gttgaacgta tcattgtgat cagcgatgta gtcgctcaag ataaattgag
     9601 aaagtttcta ctaaaagaag ctgcaccgcc ggggatcaca gcaaatgtaa taaccgtgca
     9661 gaaaatgatt caaatctatc atagtggatt attatcacga gcaaaagtga tgcttttatt
     9721 caccaatccc caagatgttg aagcggttgt ccgctgcggt gtacagttga agtcgttgaa
     9781 tatcggcggt atgagtttta ctgaaggcaa atcaatgatt accaattttg tttcagtaaa
     9841 tcaacaagat attgattcct ttcgttactt gaacagtcaa gaagtggagt tagagattcg
     9901 aaaagtacct gctgacagga aaatcctttt gatggaacta ctagcgaaaa tcaaaaaggt
     9961 gtagcaagaa tggttgttgg aaaaggtcaa ataattctgt tgtaatggtt agcaattatt
    10021 aatatttttg aatttgttac aacaaaagta aataggaggt ataaatatgg tagggattat
    10081 cctagcaagt catggacaat ttgctgaagg aatcttacaa tccggttcaa tgatctttgg
    10141 cgaacaagaa aacgtcaaag ccgtgatttt gaaaccaagt gaaggtccag atgacttgag
    10201 agccaaattg gaagaagcgg ttgcttcttt tgataatcaa gacgaagtgt tattcttagt
    10261 tgatttatgg ggcggaacac cgttcaatca atcaaacaca ttattcgaag agcacaaaga
    10321 taaatgggca atcgtcagcg gtttgaattt accaatgttg attgaagcct acgcatcacg
    10381 cttttcaatg gaatctgctc atgaaattgc agcacacatc attgaaacag caaaagacgg
    10441 tgtaaaagta aaaccggaag aattagaacc ggcagaagca ccgaaagcag cagttgaaga
    10501 cgcacaacct aaaggagcac ttccagaagg aactgtggtc ggagacggaa aaatcaaata
    10561 tgtattagca cgtgttgact cacgtctgtt acatggacaa gttgcgacag cttggacaaa
    10621 agcagtgcaa ccaaaccgta ttatcgttgt ttcagatgca gtatcaaagg atgatctgcg
    10681 taagagacta atcgaacaag ctgctcctcc aggtgtaaaa gcaaatgtta ttcctattag
    10741 caaaatgatc gaagtagcaa aagaccctcg ttttggaaat accaaagcat tgcttttatt
    10801 tgaaaatcct gaagacgtat tgacagctgt tgaaggtggc gtagacatca aagaattaaa
    10861 tgttgggtca atggcgcatt cggtcggtaa agtcgttgta agtaaagtat tgtctatggg
    10921 acaagaagac gttgaagcgt ttgagaagct tgaacaaaaa ggtgtgaaat tcgatgtacg
    10981 taaagtacct aatgattcac gcgataacat ggatgatatt ttgaaaaaag caaaagctga
    11041 attagcaaaa gcgtaataaa taatattaaa atttatagga ggcttatcat gtctattatt
    11101 tcaataattt tagtcgtatt agttgccttt ctagctggta tggaaggtat tcttgatgaa
    11161 tttcaatttc atcaaccact agtggcatgt acattgatcg gtttagttac cggtaacctc
    11221 gaagctggta tcgtacttgg cggtacgctt cagatgatcg ctttaggttg ggcaaatatc
    11281 ggtgccgctg tagcaccaga tgctgcatta gcatcagtag catcagcaat tattttagtt
    11341 ttaggtggac aaggtgttaa aggtgttcct tctgcgatcg cgattgccgt tcctttggct
    11401 gttgcagggt tgttcttaac aatgatcgta cgtacaatcg ctgttccaat cgttcatttg
    11461 atggatgcgg ctgctgaaga aggaaacatc cgtaaggttg aaatgtggca catcattgct
    11521 gtatgtttac aaggggttcg tatcgcggtc ccagcagcag cgttgctatt tatcccagca
    11581 caaactgtgc aatcattcct tgaatcaatg ccagcatggt taacagatgg tatggctatc
    11641 ggtgggggaa tggtcgtagc tgtaggttac gctttggtaa tcaacatgat ggctacaaaa
    11701 gaagtatggc cattcttcgt tattggtttc gttgtagctg caatttctca attaacattg
    11761 attgctctag gtgctttagg tgttgcatta gctcttattt acttgaacct ttctaaaatg
    11821 ggtggttcat caaataatgg aggcggaagc aactctggtg accctttagg cgacattttg
    11881 aatgactatt aatcttgaag gaggaaaata aaatggcaga agaaaaaatc aaattatcaa
    11941 aaaaagatcg tttagctgtt gcgtggcgct ctaccttcat tcaaggttca tggaactacg
    12001 aacgtatgca aaacggtggc tgggcatttt ctatgattcc agcaatcaaa aaattataca
    12061 aaacaaaaga agaacgttct gcagcattaa aacgtcactt ggaattcttt aatacacacc
    12121 catacattgc ttctccaatt ttaggggtta cattggctct ggaagaagaa cgtgcgaatg
    12181 gcgcgcctgt tgatgatgta gcgattcaag gggttaaagt aggtatgatg ggtcctttag
    12241 ctggtgttgg tgacccagtg ttctggttta cagtacgtcc aatgctaggt gcactaggtg
    12301 cttcattagc tatgggagga aatatccttg gaccaatcat cttcttctta ggttggaaca
    12361 ttattcgttg ggcattcatg tggtatacac aagaatttgg ctacaaagct ggttctaaaa
    12421 ttactgatga cctttctggc ggattgttac aagacgtaac aaaaggtgct tcaattttag
    12481 ggatgttcgt attagctgcc cttgtacaaa gatgggtatc aatcaaattc ttaccagttg
    12541 tatcaactgt aaaattagat aaaggtgctt acatcgaatg ggataaattg ccttcaggtg
    12601 gtgaaggaat caagagtgca tttgaacaag ttaataatgg cttagccctt tctcctgaaa
    12661 aggtaacaac attacaagac aacttagacc aattgattcc tggtttagct gcattaggat
    12721 taacattgtt atgtatgtgg ttgcttaaga aaaaggtttc tccaatcgtt atcatccttg
    12781 gtttattcgt agtcggtgtt gttggacacg tcatcggact tttataatcc ataaaaatat
    12841 agctcgggcg ttgtcccgag ctttttttat atagtatact gttcataaac aaatatctgg
    12901 agggagaaaa tggttcaatc aatcaataca aaagtagact tggtaattga tgctacttcg
    12961 tttacgggtc tgacagatta cgggcaaatc atgataggta ataatggttt tgagttttac
    13021 catgcgcgag atagacgcaa atatatccaa attccatggg aagaagtgga ttatgtacta
    13081 gcatcagtca tgctaaaggg aaaatggatt cctcgatatg ccattcaaac gaaaaaaaat
    13141 ggtacataca cattttcttc caaagaacct aaaaaagtgc ttcgtgcgat cagagaatat
    13201 gtagatgaag atagaatggt acaatcattg agtttctttg atgtagtgaa acgtggtatt
    13261 cgtagtatgt ttaaacgcaa gtaaaaaata aagaaaactt ctaagaggag gttttcttta
    13321 tttttttact ttgcagaaga aaatatgaaa tagcaaaacc aattatttgt cccctttaaa
    13381 tcccatatgc taaaattgat tagcaaagaa ggaggttata ttatgagttg gttatggaca
    13441 ttgattgttg gagccgtgat cggagcaatt gcaggtgcga tcaccagtaa aggaaattcg
    13501 atgggctgtg taacgaatat cattgctgga ctagtcggtt caagtattgg acaagcgatt
    13561 ttcggcgaat ggggaccaaa agctgcaggt atggcactta ttccatctat tttaggcgca
    13621 gtgattttgg tagcagttgt ctcatttttc tttggaaaac gatcataagt ttttacaaaa
    13681 tagtaaacta aaaggagttg cagcgagact gtgactcctt tttggcttta tttatttaaa
    13741 ataaaaagaa gttttccgga aatttttatt taactgtcgt gtacgaagaa aagtttgcta
    13801 taatggaaaa aagcgtgcaa agaaagaggg agtttcatta tgatgctacg tgtagaaaaa
    13861 ttgcgcaaaa aaatgcaaga agaaaatttg gattcatttt tggttaccag tccgtacaat
    13921 cttcgttact taacgaactt tacaggtacg acaggattag ctgttattac tttggaaaaa
    13981 gcatttttta ttactgattt tcgttatacc gagcaggcgg cagcgcaggc tcaagggttt
    14041 gaaattatta aaaatgtcgg acctattttt gatgaggtag caaacttagt acgcaaagaa
    14101 gaactgcact cattagcttt tgaggaaaca acagtctcat ttttagaata ttcggtttta
    14161 gaagaaatca tcgatgcgga attagtacct gtttcacaga tgatcgaaga actcagagaa
    14221 gtgaaagatg aagaagaaat cgctattatc gaaaaagcat gtcatattgc ggatatggca
    14281 tatgatcaca tcctgaaaat gatccaaccg ggcatgactg agattgaagt cgcaaatcaa
    14341 ctagactttt atatgcgttc tcttggcgct tcaggtgttt cttttgatac gatcgttgct
    14401 agcggattgc gttcggctat gccgcatggt gtagcaagca aaaaaatcat cgaacaaggt
    14461 gacttgatca cattggactt tggttgctat tacgaagggt acgtttccga tatgacacgt
    14521 acattcgcta ttggtgatcc tggggaaaaa ttaaaagaaa tttatcaaat agtcttagat
    14581 gctcaattag cagttattga tgctgcaaaa ccaggaatga ctggtgtcca attagatgca
    14641 gttgctagag attatatttc aaaacatggt tacggggaag catttggaca ttctacagga
    14701 catgggatcg gtttagagat ccacgaagga ccaaacgttt cttctcgtgc agaaaagcaa
    14761 tttgtaccag gaaatgtgat cactgatgaa ccagggatct acttaccagg aatcggtgga
    14821 gtacgtattg aggatgactt gttgatcaca gaagatggaa atcgtgtgtt gactcgttca
    14881 ccaaaagaat tgatcatctt atagtttcat caatagaaga agtaagcgta aaaatcagtg
    14941 ttcacagact ttgttataga aaatcactcg atttaatgat acactataga agaactttta
    15001 agctgtaaga gataataaag ttgggtgttt tctccaattc atagcagttt gcagctgatc
    15061 ggcggcagtt ttcttaccac gtgatcacta tgccgcatca tagagaattc ggatgtatct
    15121 cgtgcttagg caaagggagg aataaataaa tggcagatga aaaaaatttg attttaaacg
    15181 caaaccaaga tttaggagag atcgtgatcg ctcctgaagt catcgaagta attatcggga
    15241 ttgcagcttc taaagtagaa ggcgtatacg gaatgcgcgg aacttttgcc agcaatgtca
    15301 ctgaattatt aggacgtgca gctcacggaa aaggtgttta cttagcaaac gaggaagatg
    15361 gcttgaaagt agatctttac tgttatctag aatatggtgt ttcagttcct aaagtagcaa
    15421 tggaaatgca ggaacgggtc agccagcaag tccttttcat gacggatatc gatttatctg
    15481 aagtcaatat ccatgtagta gctgttgttc ctgaaaaatt agaacaacca acaatcgaag
    15541 aactttttga agacgaagag gaagagaatg aataaagaat tatcaagaca cgagattcgg
    15601 gaaatggcat tgcaggcttt atttccatta gacttcaatg cagacctaac aaaagaagat
    15661 gcgattttca acgcaatcga attagaccac cgcgacatga tcaacgaaga tgaatcagag
    15721 tttgttcctg tttatcttga tacgctagtt ggcggtgtct gtgcaaaaaa agatgaattg
    15781 gataaagtga ttgaaaaaca tttaaaaaac aattggcaca tcaatcggat ctcaaaaatg
    15841 gatttggtga tcttgcgtat cgcgattttt gaaatgactt atgtgacaga tgtaccagcg
    15901 gctgttgctt taaatgaagc aatcgagttg gcaaaaacat ttagtgatga ccgttcacgt
    15961 aaattcgtca acggtgtttt atccaatgta ttgaaagaat tagaagctgg ggcgtaagtc
    16021 ctagcttttt
//
LOCUS       DAFLWC010000069        15900 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.070, whole genome shotgun sequence.
ACCESSION   DAFLWC010000069 DAFLWC010000000
VERSION     DAFLWC010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15900
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.070"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(52..522)
                     /locus_tag="L1V17_002105"
     CDS             complement(52..522)
                     /locus_tag="L1V17_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HBN1236857.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(681..1139)
                     /locus_tag="L1V17_002106"
     CDS             complement(681..1139)
                     /locus_tag="L1V17_002106"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBN1236858.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1310..2455)
                     /locus_tag="L1V17_002107"
     CDS             complement(1310..2455)
                     /locus_tag="L1V17_002107"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HBN1236859.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2468..3385)
                     /locus_tag="L1V17_002108"
     CDS             complement(2468..3385)
                     /locus_tag="L1V17_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HBN1236860.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3813..4376
                     /gene="efp"
                     /locus_tag="L1V17_002109"
     CDS             3813..4376
                     /gene="efp"
                     /locus_tag="L1V17_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBN1236861.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            4477..4647
                     /locus_tag="L1V17_002110"
     CDS             4477..4647
                     /locus_tag="L1V17_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236862.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            4862..6121
                     /gene="lysA"
                     /locus_tag="L1V17_002111"
     CDS             4862..6121
                     /gene="lysA"
                     /locus_tag="L1V17_002111"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBN1236863.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            6108..6908
                     /gene="dapF"
                     /locus_tag="L1V17_002112"
     CDS             6108..6908
                     /gene="dapF"
                     /locus_tag="L1V17_002112"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBN1236864.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            6911..7792
                     /locus_tag="L1V17_002113"
     CDS             6911..7792
                     /locus_tag="L1V17_002113"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBN1236865.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            7789..8505
                     /locus_tag="L1V17_002114"
     CDS             7789..8505
                     /locus_tag="L1V17_002114"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBN1236866.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            8511..9206
                     /gene="dapD"
                     /locus_tag="L1V17_002115"
     CDS             8511..9206
                     /gene="dapD"
                     /locus_tag="L1V17_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBN1236867.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            9222..10223
                     /locus_tag="L1V17_002116"
     CDS             9222..10223
                     /locus_tag="L1V17_002116"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBN1236868.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            10220..11581
                     /locus_tag="L1V17_002117"
     CDS             10220..11581
                     /locus_tag="L1V17_002117"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBN1236869.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            11541..12692
                     /locus_tag="L1V17_002118"
     CDS             11541..12692
                     /locus_tag="L1V17_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBN1236870.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            12667..13836
                     /locus_tag="L1V17_002119"
     CDS             12667..13836
                     /locus_tag="L1V17_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBN1236871.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            14011..15390
                     /locus_tag="L1V17_002120"
     CDS             14011..15390
                     /locus_tag="L1V17_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBN1236872.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            15671..15900
                     /locus_tag="L1V17_002121"
                     /pseudo
     CDS             15671..15900
                     /locus_tag="L1V17_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5202 a         2803 c         3384 g         4511 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tcttttttta tttttattaa gttaaagaac
       61 ggattcaatt gcagcggtca ttttcaatgg agaagtttgt ggtgcaaatc gttcgattac
      121 tttgccattt ctatcaatca aaaatttagt aaaattccat tttattgctt tagtgacagt
      181 accaggagct tcatttttaa gataagtaaa aagaggatct gtattttctc catttacgtc
      241 aatcaattga tgcataggga aggtaacgcc ataagtggtt ttacaagctt ctgctgcttc
      301 agtcgctgaa tctagctctt gtttaaattg attggaagga aagcctaaga taaccagacc
      361 ttgtgtctga taagcttggt aaagttcttc taattgttta aattgaggtg ctagaccgca
      421 ttttgttgca gtgttaacaa tgattatcgg tttgcctgca tattttttca atgaatagac
      481 agtgccgtct tctaaagtag tttcaaaatt ataaatagac ataaagtttt ctcctttcta
      541 ttttatataa taaaaagagc gctaaactga aaactagcta tttgttttcc cgtttagaac
      601 tcttttcaga caataaatat ttaataaaat acgaagataa gatagctata ttgcttctca
      661 tctttacgtt cttttagaaa ctatgcttct acttcagacc attcatcgcg ttttgctaaa
      721 aattcacgag ccaaagcttg tgcaccttct agtgtatggc tggcagccca gccacattgt
      781 gtttcattgc ttgcaggtac ttcagtagct tcaagaacat ctttcattgt tgcttcaaga
      841 acatctaaaa tgtcttcgta gctttcatga ttcaatacag tcaagtaaaa gcctgtttgg
      901 catcccattg gagaccagtc tacgatgtaa tctgcgtgat tgcggattag ttcggcagtc
      961 aagtgctcaa gtgaatgtag acttggcatg tccatgtgtt ctttatttgg ttgtttaaag
     1021 cggacgtcgt atttaatgat gacatcgcca tgcgcacccg tttttcgatc agctacacgt
     1081 acataaggtg ctttgacttt tgtatggtca agattaaaac tttcgacatt cattctcatt
     1141 tgtaagactc ctatctgttt gttcattcgt tttgatgctt ttcactaaag aattatttag
     1201 tgaaatttac aaaaacgtct ttctacttga ttctaacact tatcgtttcc aaggtgtagc
     1261 aatctgaaat attttttaga tttttctgct aagtcgttta ttgggacttc tagttcttga
     1321 ttctgtcaaa tgcctgagct aaatcgttta tgagatcctg accatactca attcctacag
     1381 aaagacggat caagccgtcc tttatgccag cctcttctcg tttttctttt ggaatagacg
     1441 catgagtcat gacagaagga atttccacta aactttctac gccacctaaa ctttctgcta
     1501 aagtaaatag ttggagtgat tcaacaaatg gaatagcaga ttcttcattt tttaaagtaa
     1561 aagaaatcat tccgctaaag ccgctcatct gctgcttagc aactccatgg agttcatgat
     1621 cgggtaatcc tggatagtag accttttcta ctgctggatg agaaaataga aaatcagcta
     1681 ccacaaaagc atttttttga tgttcctcca tacgaacact tagtgtcttg attccgcgct
     1741 gaagtaacca gctatcttgg ggaccaagta cggctccgat agcattttgg taaaatccga
     1801 tctgatcggc tagatcttta tggttagaag tcactaaacc agctactaca tcgctgtgtc
     1861 cgcctagata tttggtaccg ctatggacaa cgatatcaga accgagatct aaaggtcttt
     1921 gaaaataagg agtagcaaat gtattgtcag caataactat caatccatgt tgatgagcca
     1981 gagtggcact tttttctaaa tcagtaatct ttagaagcgg attgctaggt gtttcaagat
     2041 aaagtgcttt tgtattgggt ttgatggatt gttctatttt atcaagatta ctcgtatcta
     2101 tgatcgtgta ctcgagacca tttttagtaa gaactttgtc aaatagacgg aatgttcctc
     2161 catagacatc atctcctaat aagatatgat cgccagcttg aaaaagagaa aaaacggcat
     2221 gaatcccaga aagaccagaa gaaaaagcga atcctcgaac accgccttcc aaatcagcaa
     2281 tcagttcttc caatgcaaaa cgagtaggat taccagatct tgaatattca tattgtttag
     2341 gctggccgac gccatcttgc cgataagtgg atgtttgata aataggtaca ctgacagctc
     2401 ctgttgtggg atcttcactg atgcctccgt ggatcaattt tgtttgaatg tgcatgtttc
     2461 tttcctccta taagtaaatg ttttttgata aatagcggtc tgctgcgtct ggaaaaatcg
     2521 taacgacacg atgaccaggt ggtaaacgac gaatttctct taatgctgct gcaaaagccg
     2581 caccactcga acttccaact aatagtcctt gttctcgtgc taactgccta gtatagttaa
     2641 acccttctac atcagagatt gtctcgatct gattgattga aaggggagaa agaaacggcg
     2701 gaatgaattc tacaccgata ccctcaattt cgtgaggggc tggatcacca ccatttaaca
     2761 cagagccctc tggttctaca ccgattattc gaatgtcggg atatttttct ttcaaaaagg
     2821 tagaagttcc agcaaaggtt ccaccactcc caattcctgc tacaaaacta tggatatttt
     2881 ctttgatttc atgaaagatt tctggcccta acgtatgata gtaagcagca ggattatctt
     2941 tattttcaaa ttgaagaggc agatagctgt ttgatatctc ctctgcaagt tttttacttt
     3001 tgctgatggc accgatgatt ccttgctcac taggagaatg gatgatcttt gctcccaatg
     3061 ctttcatcaa ttgttgtttt tctaagctaa acttctctgg aacaacaaaa accgttctta
     3121 atttgtatgt gagtgcggcc agagcgatcc caattcctgt atttccggca gttggttcga
     3181 tgatcgtcgt tttttcattg atttttcctt gggcaaatcc ttctttgatc aaataactgc
     3241 ccaatctatc tttgatactt cctccaggat ttaaatattc tagttttgca taaatagcag
     3301 aacctttagg catagaatag tgctgattgt caaagcgata aagcggtgtg gaaccaatag
     3361 cttctgtaat tgtcgagata atcatgtggg cctcctaaaa aaagataata aaaaaaggag
     3421 ctgactatta aatcagctcc ttgaaagaca tagagaaaaa ttgagtagat aaaaagataa
     3481 gttacctggt actcattcta tgaagggcaa ttaatagaca tgacaaatag tatgctgctt
     3541 ttatgcacca tacaacagca acgattcaat tgtttttggt tgctgactgt catgtgtatc
     3601 cctccaagta aaatttttat taacgatagc atgaaaaaaa ataaaagtca aaggcttgaa
     3661 agaaaaaaat atttcgatag catcgtttac ccgtgtttat ttttctgaca aataggcatg
     3721 agaccttaaa agatagagaa tactctagtt ttctggccgg ttgtctgata caataaagtt
     3781 gattatgata aagaaaagaa ggagcaaaaa taatgatctc agcaagtgat ttaagagccg
     3841 gtatgacttt cgtacaagac ggcaaactga ttaaagttct ggatgcaagc caccataaac
     3901 ctggtaaagg aaatacagtt atgcgtatga aactgaaaga tgtccgttca ggtgcaacat
     3961 acgacacaac gttcagacca gaagaaaaat ttgaaaaagc acatatcgac acaaaacctg
     4021 tacaatattt gtacacgatg gatgatacag ctttcttcat ggatttggaa acatatgagc
     4081 aatatgaaat tcctgtagaa acagtagaag aagaaatgaa atatatccta gaaaacatgg
     4141 aagtaaaaat ccaatttttc ggtagcgaag tcatcggcgt tcaattacca acaactgtcg
     4201 tattacgtgt tgtggaaaca caaccttcca tcaaaggtgc aacagtcact ggttcaggta
     4261 agccagcgac aatggaaact ggcttagtag tcaatgttcc tgacttcatc gaaacagatg
     4321 aattgttgga aatcaataca gcagaaggtt cttatgtaaa acgtgcgtca aaataattcg
     4381 ctaacggatt gataagaatt tgaaaacaga gcttgacctc ttgaaaggca gatcatcgga
     4441 tctgcctttc aagaggtttt ttgtggaatc agcaaattga aaaataaaaa agtatttgat
     4501 tttatttata ttttgaaaga tgaatggcaa aagctagaga aagaaaaaac tgcacttatt
     4561 tatgaagaaa ttgaaatgat tcataaaatt gaaaatatcc gaactattcc gaactatatt
     4621 gaagcgaaaa tattttttca tcactaaata gtgttgaatt tatgttttta tgtataaata
     4681 gcttctaata gttcgggtat tttgttttta taaccatttt tattcttatt tttaaaaaaa
     4741 tatttcgaaa tatactagac aattcagaaa attttgttta atattattcc aataaaattc
     4801 aaatctttat caaatgaaat tccaataaaa acggaaaaaa agtgaaaaga ggaatgaaaa
     4861 aatgacagaa ttgataattg gcggagtcac agcaagcaca ttggcagaaa agtataagac
     4921 acctctgtat gtgtatgatg aagaaaagat gagacaaacg atgctgtcat tcaagcgagg
     4981 ctttgtatcg aaacgttttg atacaaaagt gctttacgcc tctaaagcat tccaaacgat
     5041 tgagatgctg catttagttc gtgaatatgg attcgggcta gatgttgtca gtggtgggga
     5101 aatctatacc gctttgcaag ctgattttcc tagagatact atctacttcc atggtaacaa
     5161 caagacgcca gaggaactga tctatgcact tgaaaatgat ttgttgcata ttgttgccga
     5221 taatttgatg gaagttgaat tattagcaga attaagccaa cgctatttaa aaaaaatctg
     5281 tatcatgctt cggttgaatg tcggagtaga agcacatact catgaatata tcgtcactgc
     5341 gcatattgat tcaaaattcg gcatgagcta tgaaagtaaa gagtgccaac aagcccttca
     5401 gttgataaaa gaaagcagct atctagagtt agaaggattt catgctcata tcgggtcaca
     5461 aatttttgat gttactgctt ggttagctga aatcgacaaa ttgacgaatt acttaaccga
     5521 ttttgaccaa cctctttcct tgaatcttgg cggagggttt gggattcgtt atacacaaaa
     5581 tgatcagccg atcccagtcg aagaggcact aaaaaaactg attgaatata cggaagaagc
     5641 tttggaaaaa cgaaaactga ccattcgtca attactgatc gaaccgggta gaagtattgt
     5701 tggagaagct ggtacaacac tatacacgat tggtttcatc aaaaagacac cacataaaaa
     5761 atattacttt gtagatggcg ggatgacaga taatatccgt ccagctctgt atcaggcaga
     5821 atacgattgt gatttagcag caaaactgtc ggaagaaaaa acagagaaag tgacgattgc
     5881 aggaaaaatg tgtgaatcag gcgatgtggt aattaaagaa gcttatttgc cgaaagcaga
     5941 atcgggtgat cttttagctg tttattccac gggagcttat ggatactcga tgagcagcaa
     6001 ctacaatcga gcgacacgac cagcagttgt ttttgtcaat aatggccaat caagactgat
     6061 tgttcgcaga caagcatttt ctgatctact aaggggggaa gtttcctatg atccttcata
     6121 aatataatgg ctgcggaaat gattttatct tattagatta cgcagaagac acagattata
     6181 gtcaattagc cgcttcttta tgcacaaaag aaaaatatga tatagacgga ttgatcgccg
     6241 taaaaatcga tccgttggaa atgatctatt acaacaaaga tggcagccgc gcgccgatgt
     6301 gcggaaatgg cattcgctgt tttgctcgat acgtaaatga tcagaacatg atgaatgaac
     6361 aggaattcaa cgtagagaca ttagcaggca caagaaaaat tacggtgttg gatccctcac
     6421 ctttttattg cagcgtagat atgggagtgc cagatgattc tccggaaaaa atcaaagcta
     6481 atcaaactta tccaataaaa aaccaggaaa tagagatcaa tggtgaaaaa gtaacgatca
     6541 ctagtttatt tttaggaacg attcataccg ttgtttttgt tgaaaatgcg cgtgaggaag
     6601 tctggagaaa aagaggtgaa ctgatctgtc atcatccttt gttcaaagaa aaaaccaatg
     6661 tcaactttgt agaagtagtc aatgaacaag aattgatcgt ccgtacctat gaaagaggag
     6721 taggttggac acttgcttgc ggtacaggtt gctgtgcctc ttatgtggtt gctaaggaaa
     6781 ctgggaaaat ttcagcagat caggtagttg ttcacttgga acaaggagac ttgatgatct
     6841 ctggtgagga tgcgatacaa atggctggcc cagcagttca tgaatggaca agaatattgg
     6901 aggaatgaag atgataaaag gttcgatcgt ggcgctgatc acgccgatga atgaagaggg
     6961 atcagtagat tatgctggtt tggaaaaatt gatccaattc catttagatg aacaaacaga
     7021 tggattatta gttttaggta caacaggaga atcttctacg ctcacacaat ctgaggagga
     7081 gcagatcctt caactgacag taaagaaagt ggctggccgt gtgccggtga ttgcaggagc
     7141 tggaacgaat aatacgaaag aaacgattga aaaagcgaag cattttgctt ctttgggggc
     7201 agacgcactt ttggtcatca ccccttacta caacaaaaca agtgatgcag gactagctgc
     7261 tcattttaca gcaattgcag aagcctcacc gattccgctt attttgtata atgttccttc
     7321 tagaacaggc atgtcgattc caatccatgt attagtaaat ttagcagaac atcctaatat
     7381 cattggtttg aaagaagcct caggagatat ggcttatgtg atggatgccg ctcggttgat
     7441 tggagaagaa ttcttccttt acagtggaaa tgatgatttg atcctaccag taatgagtgt
     7501 aggaggaagc ggtgtaataa gtgtatgggc gaatatccaa cctaaaatag tccatgaatt
     7561 agtaaaagat acgcaggacg gaagatggca gcaagcaaaa gaaaagcaat taaatgcact
     7621 tgaactgatc catgccttgt tcagtgagac caatcctatt cctgtcaaag cagccatgtc
     7681 attattagac ttaccttccg gacctctacg cctgccttta gtttctcttt caaaagagaa
     7741 aaagaaacaa ttagctcagc ttttgttaaa agaaaggacg gttgaaaaat gaaaatcgga
     7801 ctgattggca gtggacagat gggaaataga gtcgaagaag ttgcacaaga aagaggagat
     7861 acggtccttc ttttacggac ggcacctaaa gaagcaacta cgcttgcttt tacggaactg
     7921 ccagaactgc ttattgattt ttctcatcca gataatttag agaaaatcct ttcgtatagc
     7981 ttatcatatc aacttccgtt agtcattggc acgacaggtt atacacaatc acagttccaa
     8041 gaaataaaag aacatgccaa acatgtacct gtgatgtata gtgctaattt ttcgttcggc
     8101 atcatggtga tgaatcaact aatcaagcaa gcagctgcaa tgttgcaagg ctggcagatc
     8161 gaactgattg aaaaacatca tagtcgtaaa aaagatgcac catctggtac tgcaaatatg
     8221 ctgcttcaaa caatccaaga agtgcaaaag ctgcagcccg tatacaactg gcaagggaaa
     8281 aaaagagaag aaaaccaaat tggtgtacac agtattcgtg caggttcttt acctggtgaa
     8341 catgatgtat tgtttgctgc tactgatgaa atatttacga tcaaacatga atctttttct
     8401 aatcgaatct ttgctgcagg cgcagtagaa gcagcggact ggttgaaaga tcagtcacca
     8461 ggttattaca aattagaaga tttattaatg gacaaagggg tgtaaaaaac gtggaagctc
     8521 aagaaatcat ccgctacatt caaacggcat ctaaaaagac gcctgtgaaa gtctatctga
     8581 atgtaaccga gccaatcgaa tttaaagaaa gtaaagtttt tggtgaagga agcagcttcg
     8641 ttgtttttgg tgactatgag acgattgctc cggttttaga agctgaatca gaaaaaatca
     8701 ttgaaatcga aatcgaaact gctgcaagat acagcgcagt tcctttgcta gatattaaaa
     8761 aaattaatgc tcgtatcgaa ccaggtgcta ttatcagaga tcaagtgtca atcggcaaca
     8821 atgccgtgat catgatggga gcgattatca atattggtgc agtaatcggt gaaaacacga
     8881 tgattgatat gggtgctgtc ttaggtggac gagcgacagt gggcaaaaac tgccatattg
     8941 gtgcaggagc tgtcttagca ggtgtgatcg aaccagcatc ggccaaaccg gttatcgtag
     9001 aagacggcgt actggtaggt gcgaatgcag tgattgttga aggtgtccat atcggaaaag
     9061 atgcagtcgt ggcagcagga gcagtggttt tagaagatgt ggcagcagaa actgttgtcg
     9121 gtggaatacc tgcacgtgta ttaaaaataa gtgatgatca gacaaaagaa aatacagcat
     9181 tgattgctgc gttacgcgaa ttatagagga gatggagaaa aatgcgcgaa atagatacct
     9241 gtattgtggg ggcaaccgga ttagtcggcc aaacgatgct caaagtgtta gaagaatatg
     9301 attttccagt aggacgattg aaattattag cttcaaaacg ttcagccggt aaagtttgtg
     9361 tattcaagaa aaagaaacac actgtacagg aattgacaga aacttcattt gaaggatatg
     9421 atttagcgct attttctgca ggtgcttctg tatccaaaga gtttgcgcca atcgcacgaa
     9481 gtcagggact atttgtcata gataattcct cagcatggcg ggaagattcg gatattccat
     9541 taatcgttcc agaggtcaat ctggaagact atacattgaa tcggctgatt gcaaatccaa
     9601 attgttcaac cattcaagcg gtacttccgc ttaaagcttt acaagaagcc tttggtatcc
     9661 agcgagtcaa ttattcgacc tatcaagcag tttctggttc cgggcaaaaa ggcattgaag
     9721 atcttcatcg tacgcaaaat gacgaggaac cagttttgta tccttataat attagccaaa
     9781 cggtgattcc ggaaatcgat cagcctttgg aaaatgggta tacaaaagaa gaacagaaaa
     9841 tgataaatga gacccgtaag attctgcatc agcctgcttt gccagtatca gcaacctgcg
     9901 tacgtgtgcc aatcgaaaat ggacatggag tctctgtggc agttcaactg caaaaagagt
     9961 ttacgacgga agaaattaga gagtgtctca gccagtttcc agggattcaa ttagaagatg
    10021 atctagcagc acataaatat ccgacgagca ttcttgctag aggaacagat atggtttatg
    10081 ttgggaggat cagaaaagac acttctttag agaacggatt gttgttctat acgactgccg
    10141 ataacatacg caaaggagcc gctgcgaatg ccgtacagat tgctgcagct ttaatgcaga
    10201 aaatagcgga ggtggcaaga tgagtaatac gctgaaagta gcgaaattcg gcggaacatc
    10261 gatgtctcat gaagagcaat tcaaaaaagt ccgtacaatt gttctttcag atcccaatcg
    10321 ccaagtgatc gttgtttctg ctttaggcaa acgtacgtca gatgatgaca aagtaacaga
    10381 cttactttat ttgatttatg cttaccttca gcatcatgtt gattggacac ccctttggaa
    10441 aaggatttgt gatcgtttca ttcaagtaag agatgttctt gccctgcagt tacctattga
    10501 agatgaacta gcacgcatac agaaacaact ggaagacgaa aagataactg aagattattt
    10561 agtaagtaga ggtgaatatc tgactgctca actgatggct gagtatcttg gttaccagtt
    10621 tattgacgca aaagacctga ttttctttga ctatgatggg aaaatcgatc aggaaaaaac
    10681 agcacaggaa atcacaaaag catttaaaag atatccgaaa atggttgttc cagggtttta
    10741 cggggcgaac cctgcaggaa aagaaaaatt attgggccgt gggggaagcg acattaccgg
    10801 cgcgatactg gcgaagatgt tgcaagcgga aagttatgag aattggacgg atgtttcagg
    10861 aatcatgatg gctgatccgc gaatcatcga tcatcctaaa atcatcgagg aaatctcttt
    10921 tagagaactg agagagatgg cttatatggg ggctaacgtt cttcatgaag cagctgtttt
    10981 cccagttcaa gaggctgata tccccatcca aataaaaaat accaatgatc ctttcgctca
    11041 agggacaaaa atatcgaatc acgaaataga aaaggaaaat ggactgacag gaatagctgg
    11101 acgcaaggat tttctttcca tcactttatt caaacgtcat atgtccgatg aaatcgggtt
    11161 tatctggaaa gcaatgagca tttttgctaa acatgagata tcaatcgaac atattccttc
    11221 agggatcgac aatatcggag tgatcgtctc agcagaagcg attgccgata agttatttct
    11281 catcacgaaa gaattaaaag aaacacttgg cgtggaagaa atcgtcgtga tcgaagactt
    11341 agctttgatc tctgtcgttg ggggtccgca taaagaattg attggattat ctgggaaagt
    11401 gttatcgata ttgaacaaat tagaaattcg cacatcgatc ttatcacaag gagcacagga
    11461 gttgaatctg atcatcggtg taccgaataa tcaatatgaa acagtagtga agggtatcta
    11521 tgaagggatg gtgaatacgg atgctgaaag aatatcgaat ggcactccat caaattcctg
    11581 aaatcgggtt tcatgaattc aagacaaaaa aatatttata tgaacaagta aaaaacagcg
    11641 aggccgttat ccatgaaatc ggcgaaacag gactactcct ttattttgat aatcagcaag
    11701 aagaaacgat tgcttttcga acagatatcg atgcactgcc agtcaaagaa gaaacgaatc
    11761 tctcttttgc ttctaagcat gaaggttata tgcatgcatg tggtcatgac ggacatatgg
    11821 cgatgctttt agggttgact gactttataa ctaaacacat tgaggatctt atttataatg
    11881 tagtactgat ctatcagcca tcagaagaaa tttccggtgg cgcacaaagc gttattcagt
    11941 caggattgtt ggataaatat gaagtacaag caatatttgg ctttcatcta tggcctggac
    12001 tagctaaggg agaagttttc tctcgaccag gacctttgat ggcacaaagc agtgaaacag
    12061 acattatcat taaaggccag tctgcacata ttgcttctag tgaaaaagga atcgatagtc
    12121 tggaggcagc tgtacgattt ttgaagaatg tttatgattt tgaccggcaa ttaccggcag
    12181 agtggaatca tctaatgaaa tttggccaaa tccaaggtgg aacgatccga aatgttttag
    12241 ctggagaagt tattgtatcc ggaagtatcc gttcttacag ttcagatatg caaaattatt
    12301 tgaagagggg attagaccat ttagcagaac agtttcactc tacagctact atttcttttc
    12361 gctataatga cggctatcca gctgtaatca accatagagg cttatatgca gcactgttag
    12421 attcaaacaa actacatgaa ttagatgctc cagttcttca agccgaagat tttggcatat
    12481 atacgcaaca atatccatgt gtatttttct ttttaggtgt cggtgatacc cctgctttac
    12541 atgatccgac gttcgatttt gatatggatg ttttagaaaa tggtgtagaa tggtacaaaa
    12601 cgattctttt tacagaaaat cttcttgtaa aaatcgatag cagttcaaaa gaggagcgag
    12661 taaataatga tgaatttatc caatcgattt agtcctaggc tttctagaat agaagtatca
    12721 aaaatacgac aattcgatca gcaaatatcg tcgataccag atgtgatcaa actcaccctg
    12781 ggagaaccgg attttccaac tcctgaacat gtcaagcaag caggaatagc agcgattgaa
    12841 gaagactttt ctcactatac cggaatgaga ggattagagg aactgcggga agcggcttgt
    12901 atatttcagc aacagcgtta tggattaact tatgatccgc aaacggaagt tttgacgaca
    12961 gttggtgcaa cggaagcgat tgcctctgcg ttgttatctg ttttggaaga aggagacaag
    13021 gttcttattc cagcgcctgc ttattcagga tatcagccat tagtggaact agctggtgct
    13081 gaattgatcc cgatagatac ttctgacaca gggtttgtct gtcagccgga acaatttgaa
    13141 cgagcatttg aacaatatgg atcagctgtc aaagcagtca ttttaaacta tcctaacaat
    13201 cctactggga cgacattgtc tgcaaaacaa ttgaaagcaa tcgctgaggt tttaaaaaaa
    13261 tatccggtat ttgttataag tgatgaagta tatgctgaat tgacttatag tggaacgcat
    13321 atgtccatag ctacttatct tccagaacaa acaatcgtga taagcgggtt atccaagtca
    13381 catgcgatga ctggttggcg agtgggcttt atttttgctc aaaaagccct tattgacgaa
    13441 ctaattaaag tccatcaata tctggtgact gccgctacaa cgatgtcgca aaaagctgcg
    13501 gctgaagcgc taataaatgg ggtgaaagat agcgagaata tgaaagagca atatcaaaca
    13561 cgaagagact atctggtcca gcaattggcg cctttaggat ttgaagtgac ccagccaaac
    13621 ggtgcatttt acttgttttg caaactccca gctgccattc aaactgactc ttggcagttt
    13681 tgtgtagaat tagcggaaca ggcaaaagtt gcgtgtatcc caggaattgc atttggccca
    13741 gaaggagaag gttatatccg gatttcttat gctagcagca tggaaaaatt acatgaggcc
    13801 tgcaaacgga tcaaagactt tttaacagaa cagtgattca tagattttat caaaaaaaca
    13861 atcgttaatt ttgcggtata ttctgcaagg agacgattgt tttttaaatt tagttcaaat
    13921 gaacgcgttt cttttgattc ataactaatg taatgttaag tttaaattgt ttagaatgat
    13981 tttaaaagaa tattcaagga ggtttcatca atggaaaaaa tcaaagttgt cattgtaggt
    14041 gcatctcatg gagggcatca atcgatcttg gaactattga cacgatacgg tgaaaatgta
    14101 gatatcacgc tatttgaagc aggagactat atttccttca tgtcatgtgg tatggagctg
    14161 tatttagaag acaaggtaac agatgtaaat gatgtacgta atttcagacc agaaaacttt
    14221 ccgcaatcca atgttcatat tttaaataat cacgaagtaa aaacgatcga tgccgataaa
    14281 aaaacagtaa cggttactag cgcatcagat aacgaaacaa aagaatatcc ttatgacaaa
    14341 ttgattttga gttctggtgt caaaccaaac aatctgccag taccaggagc agatctagaa
    14401 aatgtctact tgatgcgtgg atacaattgg gcaaccaaaa tcaaagaaaa attaaatgat
    14461 ccggctatta aaaaaatcgc tgtcgtaggt gcgggttaca ttgggatcga agcagcagaa
    14521 gcaagccgaa aagctgggaa agaagtcgta ttgcttgatg tgatcgatag acctttaggc
    14581 acttatttag atgctgagat gacagatatt ttagaacaac acctaaatga aaacggtatt
    14641 gaagttttga caaatgcaaa aatcgaagct tttactggta acggaaaagt tgaggcaatc
    14701 aaaacaagtg aaaaagaaat cccagcagat ctagtcattc aagctgccgg tgtgaaggca
    14761 aatacagaat ggttaaaagg gatcgtcgac ttagatgaac gtggctggat ccaaacaaat
    14821 gaatacttgc aaacgaatct tccagatgtg tatgcagtag gagatgctac acttgcttat
    14881 tctatcccag cacgcaaaaa aatgccgatc gctttagcga ctgttgcacg tagagaagca
    14941 cgttatgtag taaaacatct ttttgaagaa gtaccaaaca aaccgttcgg cggagtcgta
    15001 ggttcctctg cattaagtgt ctttgactat cattttgcag caagcggatt gaatagcttt
    15061 acagcagcaa aagcaggagt agatgtacga gtgtcttatt atgaagatac gttacgacca
    15121 aaatatgtac cagaagaaca aggaaatcca aaagtgtcca tccaattatt ctcggatcca
    15181 atgacccatc aattgctagg aggagcagta ttatctacct atgatgttac aggtcaagga
    15241 aatgtattgg cactagcgat ccaaaacaaa ctgactttag aagaactagc agaagctgac
    15301 ttcttcttcc agccaggctt tgaccgacaa tggagcatgt tgaatctagc cgctcaacaa
    15361 gcgttaggag aagaaccatt tgtagaataa gaaaacgaaa tatttgaaaa gaggttgtga
    15421 aaaagctgcc ttgcatcaag taataagaac agccaagtaa aaacagcttc ttatgttttt
    15481 aacttggctg gacttattac cgcagatgca agcttttgaa caccgtttat tttcaaaaaa
    15541 gggactgtga cacgatttgt gtaccgaccc ccaaaagtta gaccaaaaaa tctaactttt
    15601 ggaggtcggt attttttatg gttaaatata cttttgaact taaattaaag atcgttcatg
    15661 attatttgga tggcaaaggc gattggaccg taaaaatcca gatcaagaga ttgaagcgga
    15721 aatgcttaaa attcgggaga agcacaagga ttatggctgt ttacggatga ccaatgaact
    15781 aagaaaccgc ggtttctcta tcaataaaaa gaaagttcag cgcttgatca agaagctagg
    15841 aataaaagta acggcataca cgcgtaaatc acgtcgctac aattcttatc gaggaaaagt
//
LOCUS       DAFLWC010000070        15467 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.071, whole genome shotgun sequence.
ACCESSION   DAFLWC010000070 DAFLWC010000000
VERSION     DAFLWC010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15467
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.071"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            103..453
                     /locus_tag="L1V17_002122"
     CDS             103..453
                     /locus_tag="L1V17_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HBN1236873.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            552..1082
                     /locus_tag="L1V17_002123"
     CDS             552..1082
                     /locus_tag="L1V17_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBN1236874.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            1236..2387
                     /locus_tag="L1V17_002124"
     CDS             1236..2387
                     /locus_tag="L1V17_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBN1236875.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVFLLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(2496..4535)
                     /locus_tag="L1V17_002125"
     CDS             complement(2496..4535)
                     /locus_tag="L1V17_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HBN1236876.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDQYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGEKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKIITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKDDDDSATKRASELLQYLNQNYQ"
     gene            complement(4593..5150)
                     /locus_tag="L1V17_002126"
                     /pseudo
     CDS             complement(4593..5150)
                     /locus_tag="L1V17_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     gene            complement(5689..5895)
                     /locus_tag="L1V17_002127"
     CDS             complement(5689..5895)
                     /locus_tag="L1V17_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236877.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(5911..6525)
                     /locus_tag="L1V17_002128"
     CDS             complement(5911..6525)
                     /locus_tag="L1V17_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBN1236878.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(6672..7355)
                     /locus_tag="L1V17_002129"
     CDS             complement(6672..7355)
                     /locus_tag="L1V17_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBN1236879.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(7464..7922)
                     /locus_tag="L1V17_002130"
     CDS             complement(7464..7922)
                     /locus_tag="L1V17_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HBN1236880.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(8006..9769)
                     /locus_tag="L1V17_002131"
     CDS             complement(8006..9769)
                     /locus_tag="L1V17_002131"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBN1236881.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(9990..11450)
                     /locus_tag="L1V17_002132"
     CDS             complement(9990..11450)
                     /locus_tag="L1V17_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236882.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(11658..12584)
                     /gene="glsA"
                     /locus_tag="L1V17_002133"
     CDS             complement(11658..12584)
                     /gene="glsA"
                     /locus_tag="L1V17_002133"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBN1236883.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(12607..14034)
                     /locus_tag="L1V17_002134"
     CDS             complement(12607..14034)
                     /locus_tag="L1V17_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1236884.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(14065..15279)
                     /locus_tag="L1V17_002135"
     CDS             complement(14065..15279)
                     /locus_tag="L1V17_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HBN1236885.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
BASE COUNT         4422 a         3093 c         2661 g         5291 t
ORIGIN      
        1 ttgtcacaat cctttttgtt tttttgaata atcgcttttt cttctctttt tcttatatac
       61 tataagtagt aaataatttg aaaaaaagaa aggtgactga ttatggcgca aaatcgtatt
      121 tttacgacaa gttttgcaag cgtttatcct atgtatgtag caaaagcgga gagaaaagat
      181 cgtataaaag aggaagtaga tgaaatcatt tgttggctga cgggttattc ccaaacagaa
      241 ctagaatatc aactacaaaa acaagtgact ttcgaacaat tttttgcgga agcccctgtc
      301 cccaatcctt cacgttcctt gattacaggt gttgtttgtg gtgtacgagt agaagacatc
      361 gaggataact tgatgaaaga aattcgttat ttagataaaa tgatcgatga gctagcaaaa
      421 ggcaaaaaaa tggaaaagat cctcagaagt tgatttttcc agagatattc ttctccttcg
      481 ctcattttgt aacatttaat ttggtaaaat gactagttca cgttaaaata agtcaaagga
      541 ggttttctta tatgtttgag acgattaaac aaaatattca aaaatacgcc ttattaagag
      601 ctgctgttta tattatttct gggattgcga ttgtgctaaa cccttctgct gtttttcatt
      661 ttatcggtta tctgatcacc gcctatcttg ttttgcttgg gttgttgaat ctttttgagg
      721 cttaccgttt taaaaggaaa acaggttctt ggagtatcgg tctgttcagt ggtctttttt
      781 tcctgatctt agctctgatc gtctatgctt ttgcacctgc aatcgtttct atcctgccga
      841 ttcttcttgg attagctgtt atcatcaaca gcttgttcca gttgttcttc agcatgaata
      901 caaaagctaa aagttggagt gtttatagta gtattctgtt gttgattggc ggattcgtct
      961 tattgttcaa tccattcaaa agtttgatgc ttctattcca aatattcggc tttattttga
     1021 ttttcatggg catccaggag attatcaatt tcatcagaat aagaaaaatg actatacgtt
     1081 aatcattttt agttattaaa atagaccgta taaaaaccaa caatccaaaa aaatcttttg
     1141 gattgttggt ttttttgtga gtatattttc ctattttttc aataatgtat gttatgctaa
     1201 gttcgggcta tattttatac aaaggaatga tgagaatgga atttattggt attttatgcc
     1261 tgatattgat ttcaacaacg attggctcac atatctcgcg gagattaggt atcccagcag
     1321 tgattggaca attacttgtt ggtgttttgc taggccaagc tggattgaat tgggtcaaac
     1381 ctgatattct agtccatgac ttttcggaga ttggtgtgtt cttattaatg tttttagctg
     1441 gtctggaaag tgatttatct cttttgaaaa aatatttccg acctggtatg ttcgttgctt
     1501 tgcttgggat catcttcccg gttgtttttg gctggttgac aggcaaagca ttccaagttt
     1561 cgggaaatga agcgattttc tttgggatta ttcttgcggc aacttctgtc agtatttcag
     1621 tagaagtatt aaaagaacta aacgtagtga atacaaaaga aggatcaaca attttgggtg
     1681 cttctgtggt agatgacatt ttagtcgttt tagttctaag tttcagccta tcttttctaa
     1741 cgggggaagc ttctagcaat gcttctttac cgcttgtttt gattgaacag ctaatttatt
     1801 ttgtttttat tttcttatta gtcaaatgga ttgcgccttt cctactttca tttgcagaaa
     1861 aagtgtacgc aaattcttct attatcatcg tatcgctagt tatttgttta ggaatgtctt
     1921 acgtagcgga tcttgttggg cttagctctg tcattggtgc tttttttgct gggatagctg
     1981 tcagtcagac aaaggttaaa gaagaagtat accacaatgt agaggcttta ggatatgcag
     2041 tatttatacc agtatttttt gtcagtgtag gattagaagt tgatttttct gactttagtg
     2101 aacaactact ctttatttct atattgacgc ttgtagcgat tttgaccaaa ttgcttggag
     2161 gttattttgg tgctcagatt gccggttttt ctcaacatag ttcattgatg gtcggtgctg
     2221 gtatgatttc gcgtggagaa atggctttga tcattttaca aattggacag caaagtcaat
     2281 tgatcgaacc acagtactat tcacctttag ttatcgtgat tttattaagt acacttattt
     2341 ctccacttgt tctcaaatat tttacaaaaa aagtttatga agtgtgagta aatcaaaaag
     2401 aagttgtgaa agagacatcg tgaaaaccgt ttatttgaaa aaaggactgt gacgataacg
     2461 ccacagtcct tttactgtac ttaaaaagca attttttatt gataattttg gttgaggtat
     2521 tgcaatagtt ccgatgctcg tttggttgct gaatcatcat catctttatt ttccaacatg
     2581 ctgaccatca tataaccttg gttatcaaga ttgaaagcaa acaagaaact gttctcttgc
     2641 ccctttacat cctgtttttc tttgatttcc gctgtaccag ttttcgctgc caacggaatc
     2701 cctaaagcag aaagagaatg tgctgtacca tttacatctt gcacaacttc tctcagatct
     2761 ggcacgatcg tttgtactgc tgtttcgctg atgacattct tcttatcttt tgtctcttta
     2821 tctgcaatca atttaggata gacaagtgtg ccattgttgg taaaaacaga atacattgct
     2881 gcttgctgga taggagtaat tagaagttcg ccctgtccat atccagtatc agctagcaag
     2941 atatctgagt taaagctatc ttcattagaa atttgtgctg gattcatact aattggcaaa
     3001 tcaaggtctt caccaaaaat gaatttatct aagcctgtac gaaatttttt ctcacccatt
     3061 ttcaacgttt cttgtgccgc atatatatta tcggaataga tcaaagcagt ttttaagtct
     3121 acttgtgata catcactact gacacgcgtt gttttaaaag atccccaaga actgtctttt
     3181 tgccatttaa gcccgttgat cgtcaacact tcatttggat cgatagtgcc gttgtcgaga
     3241 ccgattgctg ctgtaattat tttaaacgta gatccaggag cataacctgt cgcaaatcgg
     3301 ctgatgaatg gatgttcagg attttcttca taagctttgt aatcttcttg tgagatcccg
     3361 tttgtcattt tgtttggatc atagcttgga gagctagcaa gcgcaagaag atcaccggtt
     3421 tttggcgttg tcgcaacagt tgatccagct tttcctccta gactgtcaaa agctgttttt
     3481 tgtgccttcg catcgattgt caatttgata tctttgccat tttgaacttc atgttcgatc
     3541 agaacttttt tctctacacc gtctgcatct gtaatgctta atttctcacc tgttgtccca
     3601 cgaagatcct tatcaaaagc catctccaaa cctgagcgac cgatttttcc attactgctt
     3661 aattctggat tcttatcaat atcttctgct gtgatatctc ccacgtaacc aatcagctga
     3721 gcagctgctt cacccaaagg ataatatctg ccgtctactt cttgaatggt agctccagct
     3781 ggaagttctg gcgttgctcc atcaatgatt ttcaatggga caaagtaatc gggttgtacc
     3841 cagctttgtg aaatcgcctg attgatagca tcttctgtta agtcgaagga ggaagcaatc
     3901 gctttgatat tggctgtttt ttcgcctcca tctccaagtt tacttggaac gactcctaat
     3961 tgttttagtt tgcctgttgt tgctaatggt tcaccatttc gatctataat attccctctt
     4021 gctgcttctt gtgtggtcag gcttactttg tcatttcctt ccatttctgg aaaaaccaag
     4081 ttgggttgcc agttgatcgt ggtttgacca tcatttctgt ctaatgttcc tttataagaa
     4141 agatctttca attcacctaa tgaggtattc atctttgctt tatatgaaaa actgtaagta
     4201 gaatcgtctt ttttatctac ttttagattc gatatctgaa gtcctttgac atcagcagca
     4261 ccgtatatat tctggtattg atctaagatc tctttttcag ataatgcact tttatttgcc
     4321 gccttttttg atgtcatttc tgcagctttg ttataatctc ccttgttcaa agcttggaca
     4381 aattgctcaa ctgtcttttc tccagcttct actgcttggg tttcttgata gtgctggtag
     4441 taaaaataac cgccacccgc agctgctatt aagatcactg cgccggcaat ataagcgcct
     4501 gttcgatttt tgccgtgctt gtcacttctt ttcatttttt cctccttctc ttgcttgtca
     4561 ttcctttatt tcactattta tacctgttta ttctaacata tgtctttgag gaaatccata
     4621 ccacaatcca gaagcacact ttctggaagg ttcgtttgga tactaccaag taatttccca
     4681 accgctttgg gtagcttgaa tattgaagtt acgtctttca gctgctgaga gatagctttg
     4741 atcacttgct gctgccttct gatcctcccg aagtctcctt ctttgtcttc ccgaaatcga
     4801 gcatactgga gtaaagtatt accatccatc acttgctctc ctttgtttat atatacgcca
     4861 tctaaatcta gagatttttc tgcatcgatc ttgactccac caggaaacag ttcattaacg
     4921 caatcgataa aatcttgaaa tgtgatactt gcataatagg gagcttcaaa tttgaaattt
     4981 tcctttaatg tttgatttaa taaatcaact cccccataag agtaagctgc atttatctta
     5041 ttcattccgt aacctggaat atcgacatat gaatctctca tgatagagat cagttttgct
     5101 tgttgtgttt tctggttgta ttgtgcaacc agaagtgaat ccgagcgacc tccaccaatc
     5161 gatctttttt caccgcatct cctcctcaca cagcaatcca cttgtcaggt gaggagcgag
     5221 tttgtctcat caaataagtc agtcacaaaa atataaagaa aaggtcagaa accttttcga
     5281 acaagaattc tgacctagca tcatctcatc gtccgagttt tagcactata caacgtaaag
     5341 aaaacattct tagctattgg aaaaagcctt aatccaacag tttctgtttt acccattggc
     5401 gactttcgac gtttctgggc aacagcctat gtttgtatag gagcctcacc taacaaggtt
     5461 attactatat tctatttacg agttcatgat agacttttcc taatgattag gcaatggaat
     5521 ttgaaatgaa atagtgaaat ttaacaatct ttaatatttt ttagaaaaaa ataacaaata
     5581 agttgaaaga atcccgttgc aaattctttc agttgcacca ggattctttg ataatttttt
     5641 agttttatgt gtttttttat atgttttttc acttttcgga ataaatattt atttgttaaa
     5701 gtaattaaac aatccgctaa tcgtttgatc tggcatttct atttccttac catctaaagt
     5761 aacagtagta acgacaaaat ggtcttgcaa tggcggaact tctaagtact gcccttgcag
     5821 aaaatcattc actgtttcat attctttttt catttctttt gaatctgtcg atggtttata
     5881 gcttattttt aacataacta gtgctccttt ttattcggga cgtgcaatcg tgaaaatttc
     5941 tcctattgct gcataatcat ttcctgccaa acggcttaca gcattcaatt ttcttggatc
     6001 gatccttcct gtcttatcat catagactgt ttcatttaaa tgatatttct gtacttctag
     6061 caaaaataaa tcagctgtta ctttattttt attccgtatc tcgacatgtt catataagga
     6121 tgtttcaaaa cgaacttttg cttctgtcaa tgctggtact gaaatgatta ctgaatcagt
     6181 taaagtcaag tcagtcaggt acagttcgct ttcctcatta ggcagattgg ctgctgtttt
     6241 atttacttct tctacgttgt cctcatcaag gatatggata acagcttctc ttgtctcaag
     6301 aatattcttt gctgtgtctt ttactgcatc ttgttttctc tggatcgcca aggataagat
     6361 gggtcgattc gaactgacga tattgaagta actgaagggt gcgatattca ctatatcttt
     6421 tgctgattta gtcgttacta ctgctactgg tctagggatg actgaaccaa tcagcaactt
     6481 gtaattttca cgttctgtca attctgaagg actccgttca aacatggttt cgccttcttt
     6541 ctataaaatt cgttaaaaag cagatcttga agacaaaatg aaaagtaatg cttttttcat
     6601 cttcttagaa tctgctttaa actatctatc aatttttctt ttttgtcaag aatctgtgcc
     6661 gtgcgtgttt tttagttatt tgctttactt gcggcttcga catatctttt agtgatcaat
     6721 tgcggacggg tgataataga tccaactacg actgaaaaag cacctaattc atatgctttc
     6781 tctacttgtt caggagagtc agtatgtcct tccataatta ctgggatatc gacttgttct
     6841 atgatttgat tcaataaatc aaaatcaggt gtctgcgtct ttcgtgaata ttctgtatag
     6901 cctgctaaag tcgtagacaa aagatcaaaa ccatcttctt gcgcttgaag cgcttcctca
     6961 aaagtcgaaa tatctgccat agctaaccga ccgtgttcgt gaatcatttg gacaagttca
     7021 gcagttgttt tttctgtcgg acgtttacga gaagttgcat ccagtgcaat gatttctgct
     7081 tgcgtctcca aaagttcttc cacttctttt tctgtcgcag taataaacac ttctgaccca
     7141 tcgtaatctc ttttgataat ccctattacc ggtaaatcaa cgattcgctt gatttcattg
     7201 atatcttctg tcgtatttgc tcgaatacca actgctccgc cttcttttgc agccaaagcc
     7261 attctcccca taataaaaga actgtgtagc ggctcgtttt ccaaagcttg acaagaaacg
     7321 acgactccgc ctttgatttg ttccagtgta tccacaatat ctcctccagt aatgttatat
     7381 aaaaatacag cttcatataa aaatgtaacc cttttctatt caggagacaa taatgagcta
     7441 tttctttcag cagacctttc ttactaaaag aaaattactt caaattcttc gtatacgacc
     7501 agcttctctt ctgtaaattc tatgttcaac gcttctttat aagcatgttt aaaaaactca
     7561 gcatggactt tccgccaata agctaatgtc cgatcccctt ctccttcttt ccaagcatgc
     7621 tctttcgtga cttcactaaa aggcaagatg gtcacattta tatttttgat gatacaaact
     7681 ggttcatttt ttccattcag gaccacgtct aattgaccaa cttttggtaa aggctcattc
     7741 tcttgtttat acagatcgta accacttgat gtaccagtct ttatcttttt tacaactagt
     7801 tcgctcaact cgtctgccat tttttctgta tccccaaatg aaaagaaacc taatttttct
     7861 gattgataac taggatattt ttcttggaac tttttgacat attcttctac ttgctgatac
     7921 ataacatcca cccctttgct ttttataatg aaaaaaccat ccagatacta gtataaacaa
     7981 ttatctggat ggtgagcata atgaattatt gaatattcaa gacacgcaga ctatcttcaa
     8041 cgatttgttt tggtgttaaa tgataacgtt cataaagctg ccctacagga acgctatccg
     8101 tgaattcttt ctctgcacca aaatttaata cgttcattga agaatcacca taataacgac
     8161 tgatattttc gccaaatcct cctgacaaac taccatcttc taatgtgatg actaattcgt
     8221 gtgtttcttt taatttatct aatgtttcta cgtcattttc tgtgatcgtt cctggattga
     8281 tcaacgttgc ttcgattcct ttttttctaa aagcttttac tgtttctttt cctaattcaa
     8341 gaaaaccgcc taaagctaaa attgctactt ttcctccatt atttactgtt tgataggctg
     8401 gaatactata atcatttgcg atagctgtac catgttctac accatgtgta ggaattcgga
     8461 ttgctacagg ctgcgctgtt tgttcgaacg cccaatctag catagagatc atatcctctt
     8521 ttgttgctgg agcaagatat ttgatgttcg ggatacttga taagtaagga atgtcaaatg
     8581 ttccttggtg tgttcggtca ctagctgaga tcgttccgcc accgactaaa ataatcactg
     8641 gattctcgtt gatcgctaaa tcatgtgata attgatcata tgcccgttgc aagaaagtac
     8701 ttgattggaa gacgactgga cgtactccct gagaagccaa agcagaagcg aaagtgatag
     8761 agtgctgttc agcgatcccc acgtcaaaat aatgatctgg atgtttttct tggaatgttt
     8821 tcagtccaaa ggcgcctggt atcgctgcat tgactgcggc aataggagct gtacttgttt
     8881 gcattttctt atccaaataa tccatgatga tcatattaaa tgtttctcca gaagttactt
     8941 gctttgcctc cccggtggac agatcaaatg gtacatgcca atgatatttc attttattat
     9001 cgattgccgg ctgataaccg cgaccttttt ccgtatggac gtgaagtaca atcggatgat
     9061 caatatcttt tacttcttca aataaacgga tcaccgtttc cagatcgttt ccattatcca
     9121 cgtaacgata atcaaatccc attgctttaa ataggttatt gctgctttta ccgttggttt
     9181 gacgaagctc agctaagttt ttatataaac tgccatgatt ctcatcaata gacatctcat
     9241 tatcgtttac taatacgatt agattggatt gtaaaacacc accattgttc aatccttcaa
     9301 aagctaagcc accacttagg gagccgtcac cgataaatgc taccacattt cctgattctt
     9361 tcttcagatc tctcgcttta gctaaacctg ttgctaagct gatagatgta gatgtgtgcc
     9421 ccactgtaaa atagtcatgt ttactttcat gttggttgga atatccgctc acttcacggt
     9481 aatgtccttt ttcaaaacca ttttttcgac cagttaaaag cttatgacca taagactgat
     9541 gggaaacatc ccaaacgatt ttatcctttg gtgaatcaaa tacataatga aacgcaatcg
     9601 ttaattctac tacacctaga ttcggaccaa cgtgcccacc tacatcgctg tccttttgca
     9661 agattttttg gcgcatctct tctgccaact gtttcatttc ctcaacagat aattttttga
     9721 catctgcggg gctattgatt gcatccaata catgtaatac tgtactcata atacattctc
     9781 tcctccgtac tatcttcttt taatgaaaat agatttgtta cactttatct attctactac
     9841 ttagagttga ctctaagtca atagcatttt aaaaaaattt cagagaaagc ttgttatata
     9901 agtagatctt cgcacgaatc aggactcaaa taaaaacctt ctacagacaa ttaaaaagct
     9961 ttgtagaagg tctcctaatt aaggtctcat caagaaatat gtttttttaa taggtgaagt
    10021 tcctgagcaa tatgatacaa atggatgttt gcacctttta atgagattgg atagatcttt
    10081 gtcttttcag tttctaatcc attttgatag ctagcagcat cgcacaaaac cactcttttt
    10141 ttcgcacata gacattcatc aggcaattct tctaatgaac gaaataaaat aggatttatt
    10201 tcagcgatgc cttcttccgc atacaaatga aattgggttc gataaaaaaa ttgtttgact
    10261 gaactttctg aaacaacaaa aatttctatt tcctgtctcc ccgcttgttc actgttgatc
    10321 aaagaaagac ttttgacgaa ttttcgaatg aaattttcat tccatcttag ttggatttga
    10381 tttttctttt tccactcttc caatatttct acaatttttc cgtacagaag ttgttctttt
    10441 tctgatagaa gatagatcct ttccggtaaa aatacttgtc catctgccca caacgtacgg
    10501 acaaattgta aaaaggattg cttgaaaata aaattttctg catcgtcgat ttcagcgata
    10561 ctaataatct gtaaaatcaa ttcattcagt gataggtcat tgagaacaaa atttttataa
    10621 acaacttcga aatcttttct taacagctcc atgttctcat tggtataatt tctactgttg
    10681 aacaaagaaa aaatataata gacatcttct tcttgtaagt ctagaattcc tttttgctct
    10741 tccaatcctt gacagactaa ttgaaataac ggcttcgttt ctgcgctttt cttatcttct
    10801 tctttcagtc caaggggaaa tgcctttctt ccgattgcga tctctattcc tcgtatgata
    10861 aaggactttt catcttccga atatcttctt ttaaaaaaat gagtctctac ataatcaatc
    10921 aactcgttac aagcttcttc tacatacgga tttttatttt catagccttc ccaattgaca
    10981 taacgtacta aagctagcaa gatgttccgc gagtcaaatt ctgggataat gatttcttta
    11041 tttttcaaat aatcattttc tttaaaaaaa tccaatacga tttttttgat tgtatatact
    11101 ttgctcaaag aaataaattc aagatcagcc agttctgtac tcgtgaatat accattaaaa
    11161 taataactta aaaactttaa aaaataagat tgaccgtaca gaaactgtgt gagctcagaa
    11221 agagcaatac catgtttgaa tacgagttta tacttatgct tctctcttac ttgttctttt
    11281 atacaatatt ctagacactc ggctagactt tctagatcgt gaaggatcgt tggtgtagtc
    11341 acccttagag aaatagctgt ttgttcgatg tctatttctt ggaattcaaa taattgttca
    11401 cacagataca cttttctaaa tatatttcgc tcgatgtaat tttccagcat tcctgataca
    11461 cgcctccagt ttttcttatg attttattta atcatatctg taaatcgtat ttttgtttcc
    11521 tttttattta gaaaagccct ttcaaaaacc aataaaaaaa gaaactggga caaaagtcaa
    11581 acaagctcac aatttcagcc tcattgtagg tagctttgag ccgtttggac ttttacccca
    11641 gcctctttca agaatggtta ttcaaagatg tcagcgtcta gttctttgac tacatctttc
    11701 aacaattgga taccagctgc gctgttacca aatggatcta gtgccgggct gaagacacct
    11761 atgccgtaac gatttggcac agctgccatc aacccgccgc ctacaccgct ttttgcaggt
    11821 acaccaacat ggacggaaaa ctctcctgat tcatcataca aaccagcagt tgtcataatt
    11881 gatttgacga ttgtagcact ttcttcagta atgatttgtt tgccattcca aggagcaatt
    11941 cctttatttg ccagcacagc agctaatttt gctatgcctg tagcggtgac attgagggag
    12001 cattgtctga aataagcatc gagtatctcc ggtacgtctc cttcgatcat ttgattacct
    12061 ttcatatagt aagcaagaga gcgattgata tcacctgttc ttgattcaga atgatagatt
    12121 tcttcattca atgtgatatt aggatcatca cagatctctt tcataaatga caagattcgc
    12181 tcaaattttt catctgcatc tttaccggca atcaacgagg ttgttgcaat cgctcctgca
    12241 ttaacaaaag gattcattgg atgtttgcga tgattgattt ccatattcat gatagaattg
    12301 aaggcaaaac cggttggttc cgtgttgatt gtttgaaaga ctttttctat tccgttgtct
    12361 ttgattgcta ataacaatac gggaactttt gacatgcttt cgatggcaaa gcgcacatcg
    12421 gcgtctcctc cctcaatcag ttgttttgta tccaaatcat aaatcgccat acctaattgt
    12481 ttgggatcca cttcagctaa tgctggaatg taatccgcca cttgtcctgt ttgataatag
    12541 tggaaatttt ttccaatcaa ttgttctaat tcttttactt ccatttgaat aaccagcttt
    12601 cattttttat ttttctgcat gctggaattt atgacggcat gcgtagatcg taaatggaat
    12661 aactaagacg ataagataag aaacaatcag aatcgtttca taaatcccat gctgtccagc
    12721 tgcgatacta gcaggtggaa caaatgagat acaaaaagca aaaagtgaag tcaaaagacc
    12781 taaacaagca acgattactt ttacaacttt tccgcctgga acctgatagg ctctttcaag
    12841 actgtcatct ttaaaaacca gcttcaaata gcccgcgaaa aacataaagt acaacatcag
    12901 gtagattaca acagtcaatg acatcgctgc aagaaatgaa agattattcc ccccgccgct
    12961 taatgtaaag acggctgccc agattgttgc aacgatccca tttgcgatca tcaaatgagc
    13021 aggaacaccg tgtgtgtttt cttttgcaaa atattcagga agtaatcctt cttctgctgc
    13081 tacgtgaagt gcttttgaag gagaggttac ccaagaagca atttctccga tgacacctaa
    13141 acaaacaaga atcgcaagaa ttttcgcaat ccatgcaaga tttggatcaa tgtgtcttaa
    13201 taggaattct aacgattgaa tcacccctgt attaagagac aaaccatgtt gaggtactgt
    13261 agtagcgacg gtcaatccgc caaaagtatc taaaatgatt gccagaataa ccaatacaaa
    13321 cattgctaat ggataatcct ttttagggtt ttccatttca tttgcatgac tggcagatgt
    13381 ttctacgccc atatatgcta aaataaagga aacaaaaaca accagcgtag gcaatttcga
    13441 aaaatcagga atcaatgttt tcatagacag tatcgtttgt agtggagcgc ctgaagcgac
    13501 ataatggatc cctaagccaa acaagactaa tgctggcaac aagataccag ctacaaaacc
    13561 gatccgagca atcaatgaag tgtatttggt tccttttaac tgtgagagta aaatagccca
    13621 gaaaataatc aataggattg ccaatttcag atatttattg ttttgtatag caccaatacc
    13681 cgttgcatag gataatgcac cagttaagaa atacagcatg gtcaagtagc caactgttat
    13741 ctcaaaccat tggaaaaaga ttgcggcaaa accgaatcgt tttcccaatg tgcgactgac
    13801 ccaagtatag acaccgcctt tttcccatcc tttcaccgtt gccatctctg ctgcgcacaa
    13861 tgccacaggg ataaaccata gcaaaccgcc taataacaag aaaaatacta agctgaagcc
    13921 tgaggtcgcg aatgtgggat attcatataa tgaaacgacc attgagatgg tcatagccaa
    13981 aaagccaaag aacgttaatt tttttgcagg aattttcgtt ttgctttgtt gcatgaatct
    14041 tcctcttttc tatttgaatt tgtttcaatt gagtttgttg ccaaagaaga aaaagtccaa
    14101 tccttcttct tgttcttctt ttgtagtagt gatcgttgta aagtgcatcg ccgattttaa
    14161 aatcactgtt gtcagcacat aggcatacac ggcagtaatg atgacaccaa tcacttgaat
    14221 ccctaagaag taccagctgc ttggattcgt tagtaaatgg ctgttagatg caaagatccc
    14281 tatcagaatc gtacctgtga atccgcccat gccatgaaca ccccacacat caagtgcatc
    14341 atcccattgt ttctttttac gaaaatcaac agcagcatga cagacgatac ccgcaatgat
    14401 cccaatcagc atggcacttt ttgcttctac ataaccggca caaggcgtaa tggctgccaa
    14461 tccagcaacg gatcctgtta gtacgtcgac aaaatcaaag ccatttcctt ttacttttgc
    14521 aatgatcagc caagtaatca tcgcaaatgc aagagcgatg aatgttgaac caaatgcatt
    14581 gactgcttgt tcatctgctc gaagtgcacc accggaatta aaaccgaacc agccaaacca
    14641 aagcagtcct gtaccgatag cagctgccat aagactgcta tgctgacttc tttctcctaa
    14701 aggaatcttt ctttgaccaa gtgtgaggat acatgctaaa gagccgaatc cagctgtcgt
    14761 gtggatgact gctccaccag cgaaatctct aaatcccatc tgatccaaaa atccgccacc
    14821 ccatatccag tggcaaacag ggaaataaat cagcagattc caaaaaataa caagtataat
    14881 atagcctttt aaattcaatc tccctgcaaa agctcctgtc atcaaaggaa cggtaatcac
    14941 gataaacatc agttggtaaa gaaagaacat taaaaatgga atcgttgcac catgaaacat
    15001 gttggggaag cttgtaacat gtctcatcaa aaagaaatct gccgggtttc caataacacc
    15061 gccgatatcc cgtccaaagg ccaatccgaa tccaccaaat acccacataa tcgttgttat
    15121 cccaacggag agaaaagatt gagacatgat cgttagtata ttattcttcc gtgctaatcc
    15181 gccgtaaaaa aaagctagac caggagtcat caggcaaacc attgctgtac ataaaatcat
    15241 gaatgctgta tctcctgtat tgataggtaa tgtattcatt tttttcgcct cctttctacg
    15301 attacgagta taaaagaagg tgtagttgtt tttttcttct gtttttttga attaatactt
    15361 gcatttataa aagacagaca attaataaaa gcttgatgtg ttgtgctctt tttcgttttt
    15421 cacacaaata aagacaaaaa ataaacggtc ttctttttat agaaaac
//
LOCUS       DAFLWC010000071        15230 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.072, whole genome shotgun sequence.
ACCESSION   DAFLWC010000071 DAFLWC010000000
VERSION     DAFLWC010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15230
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.072"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            278..787
                     /locus_tag="L1V17_002136"
     CDS             278..787
                     /locus_tag="L1V17_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1236886.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            880..2042
                     /locus_tag="L1V17_002137"
     CDS             join(880..1156,1156..2042)
                     /locus_tag="L1V17_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBN1236887.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLIPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2322..3302
                     /locus_tag="L1V17_002138"
     CDS             2322..3302
                     /locus_tag="L1V17_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1236888.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3424..4842
                     /locus_tag="L1V17_002139"
     CDS             3424..4842
                     /locus_tag="L1V17_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HBN1236889.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            4913..6382
                     /locus_tag="L1V17_002140"
     CDS             4913..6382
                     /locus_tag="L1V17_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1236890.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6392..6859
                     /locus_tag="L1V17_002141"
     CDS             6392..6859
                     /locus_tag="L1V17_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1236891.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            6895..7767
                     /locus_tag="L1V17_002142"
     CDS             6895..7767
                     /locus_tag="L1V17_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBN1236892.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFIKSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            7848..10382
                     /locus_tag="L1V17_002143"
     CDS             7848..10382
                     /locus_tag="L1V17_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBN1236893.1"
                     /translation="MKKKMKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQ
                     LFSDGKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLP
                     LIIKGNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKK
                     GAFTGAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEY
                     ANVRLILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITID
                     SKIFCSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWI
                     DPEISIDLKKMFLKSLSEIDLIELFQNHISIEESMSQLRDRILKECAGSSEYNYLESD
                     EFIALRNYVVNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEETSRNFLLSKFRKFR
                     MKNDKQKLLANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPETHCLIVMHGKITAS
                     AIARETNKLLNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNGLILLVDMGSLEQM
                     YEKIESNVIGDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFDSFQVKVQYYKGLS
                     QKKNVIVSCLSGEGISEKVKDILKRYLDNQVEILIFDFNALKKIAKEKDTMIFKNTIC
                     VLSTTEFYIQGIDCLNLENLINGNQTLEKLNKYMDSDSCEFCLNELVKLFTIEGASTK
                     LRFLDSKKVFNEIEKVLYLYEKYYDVKIPSFLRINLFLHLSGMIERIMIGDGITNEHL
                     KEGAQLFDTFLNVSKDFFSEIKDIYCIEIPKGEYELIYTIFEQTIF"
     gene            10538..11311
                     /locus_tag="L1V17_002144"
     CDS             10538..11311
                     /locus_tag="L1V17_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1236894.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            11304..12095
                     /locus_tag="L1V17_002145"
     CDS             11304..12095
                     /locus_tag="L1V17_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBN1236895.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            12105..12596
                     /locus_tag="L1V17_002146"
     CDS             12105..12596
                     /locus_tag="L1V17_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1236896.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            12614..13024
                     /locus_tag="L1V17_002147"
     CDS             12614..13024
                     /locus_tag="L1V17_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1236897.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            13028..14428
                     /locus_tag="L1V17_002148"
     CDS             13028..14428
                     /locus_tag="L1V17_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HBN1236898.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            14451..14825
                     /locus_tag="L1V17_002149"
     CDS             14451..14825
                     /locus_tag="L1V17_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBN1236899.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
BASE COUNT         5287 a         2134 c         3046 g         4763 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga aatgaattat
       61 aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct atcataagtg
      121 gtaaaatcta cttttaaatc acatgtaatc attgataagt ccagtgtttt agcggataat
      181 cagcttttta tttatttttt cttataaatt tgataaatag aaattagtat agccctaaac
      241 aaattatttg tgttttattg tttagggcta tactatattg gtacaaggaa tagaaagagg
      301 tgtttatgtg gttgataaaa ttcagtttaa tcaagttata gaagaattca tcaaagtaaa
      361 taatttaatg acccatattc aaaaacgacc aatcagaata actaatgatc taaaactcag
      421 tacgagtatg attcatttga ttgatgtgat tggaaattat cctgaaacta gtattacgga
      481 attagctgat cgattaggcg ttaccaaagg agctgtatcc caacagattc ccactttaga
      541 gaaaatgaat cttataagca tttctcaaaa aaaaggaaat aagaaaacta aacttgtatc
      601 gttaacaaaa tatggtcgaa aggtgtacga atcacataat tatttacatg aagagcttta
      661 tagctcaata aatgaagcgt tagaatcatt ctcaccagac caaatttcaa ccattaaaca
      721 gattctagaa aaagtatctt atacaatcaa tgaatatcaa gtaagtctga caagaaagga
      781 agattgacat gaaaaaaatg atttttgaat cggctacact agactagaca gaaaaaataa
      841 ggtgtgtaaa ataaatgaaa acacactgga ggaattttta tgtcaagacg tcaacgtaga
      901 acctattcaa aagaattcaa acaacaagtc gtcgatcttt atctcgcagg aaagccccga
      961 gctgaaatca ttcgagatta tgagctgact acctcggcct ttgataagtg ggtcaagcaa
     1021 gcgcaaacta ctggctcgtt tcaggaaaaa gataacttga tccctgaaca agtagaacta
     1081 attgcattac gaaagaaaaa taaacagctt gaaatggaga atgacatttt aaagcaagcg
     1141 gcgctgatat tgggacgaaa agacaagtaa ttgataccaa taagcacaaa tactcaatat
     1201 cagcgatgtg taaagtgtta aacatctctt gccaaaccta ttattatcaa gccaaaccag
     1261 ttgaagatga atcagaactg gaagaactcg ttcaagaaga atttattcgc aatcgaaaag
     1321 cttatggtac caggaagctg aagcagtgct tggccaatct aggtcttcaa gtgagtcaac
     1381 gcagaatcgg ccgtatgatg aaacagcgtg gcttgcgttc aacatacaca ttggctcatt
     1441 tcaaattcca ttcttctact tgtaacgaag ccaagaccgc caatattcta gacggaacct
     1501 tcctacagga aaagtcatta gaagcgattg taaccgacct tacctatgtt cgtgttggga
     1561 agaaatggca gtatatctgc ctgattcttg atttgtttaa tcgagaaatc atcggctatt
     1621 catgcgggga gaagaaagat gcgacgttag tcaaggaagc ttttgcaaag attccgtact
     1681 cgttgaataa tgtacaactt tttcacacgg atcgtggaaa agaattcgat aaccagacga
     1741 ttgacgaaat tttatgggcc tttaatatca cgcgttcctt aagcaaaaaa ggctgcccct
     1801 atgataacgc cgttgcagaa tccacctata aatctgtcaa agtagaattc gttcatcaat
     1861 accgctttga gacattggct aatttgcgat tagagctatt tgattacgtc cattggtgga
     1921 ataccatccg gctgcacggc acgttaggct atgagacacc gatcagtttt cgacagcaga
     1981 gattggcgca gcgaatcctt gataatgagc tcggatgtga taccggtggc gaggcacctt
     2041 aattatttga atgagcttct gccttagaga atcagattcg aggaggctcg ttgtcaaggg
     2101 cagtcggaac accagcagca agcttacgca ataccttata atttttgtca aaaaaagtgt
     2161 tgccattcca catatatctt taaacagcta ttgccagata aaaataaatg atattatata
     2221 tataaatact tatccgaaaa ggggaatgag agagtcaagg ttcttggaat gtcgaatagt
     2281 cgagtaggta gattttctat ctacaacctt gttgtttaaa aatgaaaaaa attggaatta
     2341 gagaagttgc gaaagaggca aatgtttctc ctacgactgt gtcgagggta ttgaatgatc
     2401 gtggatattt gagtgaggaa acaaaaagaa aagtttttga tgccatgaaa aaattagaat
     2461 actatcctaa tgaactggcg agagcacttt ttaaaaacga aacatatacc gtaggtttga
     2521 tttttcctac aattactaat ccatttcacg ctgagttaat tcaagatatc gagttcgagc
     2581 tttccagcag gggatataaa gtgttgctgt gcaatagctt aaacaatcca acaaaagaaa
     2641 aagagtactt gacgatgttg agaaagaatc aggttgatgg aattatagta ggaacgcaca
     2701 ataaagatat tgcggattat gatattccag ggctacctat tgtagcgatt gatagaagtc
     2761 ttggtgaaaa tacagttaca gtatcttgtg ataattacag gggtggggaa ttagctactc
     2821 aactacttgt aaatcatggc tgtcagaata tactgtgtat tcggggagat agtaagataa
     2881 agctacccgc gaatagtagg actttagcat ataaagatgt tttgaataaa ttcatgctgg
     2941 aaccgttagt cctagaagta ccatttgtaa aagaaatcaa tgaaaaaaat gaaataatta
     3001 agacatatct ggaaactcat ccaaatattg acggggtttt tgcaggagat gatttattgg
     3061 cttctttggc gattaacaac ttaggaagtt cgggcaaaag agttccaaaa gaggttaaag
     3121 tgattggatt tgatggagct caacaaacat tgatttataa tccagaatta tcaactattc
     3181 aacagcctat agatcaaata tctaaagtag cagtaaaaaa attattgaat atgattaagg
     3241 gcgaaaagga gacggatgaa ctttcacttc cagtaaagct cataaaaaaa aatacagcat
     3301 aagttaaatc ggcgaaaaat tccttcgtcg atttaaaaat atttttatga aacgggttga
     3361 catatgaaac gggttgacat atattagttg tgaagataaa aaccttttca ctggaggaag
     3421 aaaatggaga aattattaat taaaagcaat aatcatcaac tttactacca acctaaggat
     3481 gtttgggtcg gagatgttat gccttacggg aaagaaggaa aattctttat ttatcatcaa
     3541 cgtgatacta gaaatccagt tccttttgga gaaccgtttg gctgggcttt agcaactacg
     3601 aaagattttg ttcattttga agactttggg gaatctcttt taagagggga tgacaatgag
     3661 agagaccagt ttatctacgc tggttctgta tttgaggcaa atggaaaggt tcacgcattt
     3721 tatacagggt ataatcgtga attcttagcg cagggaaaga catctcaagt gttgcttcat
     3781 gctgagagtg atgattttgt tcattgggaa aaatcagaaa cagcattgga gttagaacca
     3841 caagaagggt atgatattcg aaactggaga gatccatttg tcgtttggga tgatgaaaaa
     3901 gaagaatatt tgctaatttt aggggcgcga aagggtcagg ataaacatct acaaaccgga
     3961 cgtttagtgg aatttacatc aaaagattta actaattggg aattcaaagg tgatttttgg
     4021 gctccgggat tgtataccat gtttgaaatg ccagaacttt tcaagattgg tgactggtgg
     4081 tatcttgtct attcagaata ctcagatgga aataaaatac tctatcgaat gagtcaaagt
     4141 ttggaaggtc cttggattaa gcctaaagat gaagcttttg atggacgggc ttattatgca
     4201 ggtagaacag cttatgatgg aaaacgtcga gtcctatttg gatgggtacc aacaaaagat
     4261 caagaaaatg ataaaaacaa ttatttatgg ggaggtactt tggttcctca tgaagtctat
     4321 caaaaagagg atttttcact tggggtaaaa cccatagacg aagtgtggaa tgcattcata
     4381 aatttacatg atattgccga tgtagagata gaaacagcag acacaagaga agaagtaacg
     4441 cttgtcaaaa atagtggaac tttgtttaat ttagaaacaa caatttcatt tgatgagaat
     4501 cttagtgact tttcactgag attatataaa aaccttgaga cagatgaatc ttacgaatat
     4561 cgcttcaatt tagatgaggg gcgtcttaca tttgataaaa acccttgtta cccttggttt
     4621 caatatatgg ataaaggact tattagacct atatctttaa agcctaacca atcttataaa
     4681 ctaaaagtga ttgttgatga caatataatg acactttata ttgatggaat cgctcttaac
     4741 gctcgtgtac atggttgttt tggtcaagca attactatta cagcaacaaa tggatcaatg
     4801 actgcaataa ataccaagtt ttcaaatgaa ataaagaaat aataaacgtc aatcatgtgg
     4861 caggtctgaa aatcaaacat gacctgtcac atttaaaagg gaggataaat gaatggacta
     4921 caaaaaaatt gccgaagatg tattggaaaa cgttggagga aaagagaata tctcaagcgc
     4981 tacacactgc attactcgtt tacgtttaat tcttaaagac aaaagcaaag cgaatatgga
     5041 aatgcttgag gaaatagaag gtgcaaaagg tgttcttttc aatagtggac agttacaagt
     5101 aattttcgga acaggtataa ttgaaaaggt ttacaaagag ttcgttgaat tgacaggagc
     5161 taaggaagta tccgtttctg aaatgaaaga cgaaggagtc aataattcag gaaatagact
     5221 tcaacgagct tttaaagttt tctcggatat ctttattccg atcattccag cttttattgg
     5281 ggcagcaatg gttttaggaa ttcgttcgtt gattaccact cctggaatgt ttggaatgga
     5341 tggctcattc gctgatcaca atgtattcct aaatgattta tccaaatttc tgggtattat
     5401 tgcaaccaca tttgattatt taccagtttt agttatgtat tctgcaacaa aacgttttgg
     5461 cggaaaccct attttaggat tacttgtagg atttgttatg attcatccag gactagccaa
     5521 tcggaatgat ttcgtcatgg gaactataaa gcctgattat tggcatttat ttggattaag
     5581 cattccagca gttgcgtttc aagggggtgt ttttccagca attttgactt cttggttttt
     5641 agcaaaagtt gagaaaatta caaataaata ttctcctcaa gtacttgctt acattttagt
     5701 cccaactgtg acaattgttc ttgccaactt tgcactattt ttagtgtttg gtccattggg
     5761 gaattttatc ggtaatgttt taggtggaat cattgatttc ctatatatga agatgggtgc
     5821 ctttggtgct tttgtttttg caggcgcgtt acaaccatta gttgtaacag gaacacaaca
     5881 tgctattcaa ggtattgagg caaacttagt cgcaacaact ggattcaatt atatccaacc
     5941 tatttggtca gtttcaatta ttgcccaagg tggcggttgt attggtatgt atttactctt
     6001 taagaaaaaa tctaaagata gagatattgc gatttcaagc tttattccaa cactggtagg
     6061 tattactgaa ccggctatct ttgctgttaa tttgaaatat tcaatcgttc cttttgtttg
     6121 ctcgtttatt ggtgctggtt ttggtggagc atttatgaaa atttttgatg taaaagccat
     6181 tggacaagga ttgactgtat tgccaggtct gactattgct aatccagttc ttccttatat
     6241 atttggtaat ctcatagcat tcattttacc aatcattttt attctcgctt atgataaata
     6301 taaagtgttt atccctgaag ctaaacaccg taaatttgca gaaaaaactg actcaaaaaa
     6361 attgccagtt caagtaaagt gagatgagag catgttaaat ttttttagaa aaaatgaaat
     6421 aagcgttgta gcacctgcaa ccggtgtttt tgaaaaactg gagaaattaa gtgatccagt
     6481 cttttcaaaa ggaatgatgg gacaaggatt tgcaattgat gcaaaaaacg aaacgattgt
     6541 atctccaatc gatggttttg tttcaagtat ttttcctaca aaacatgcct taggaataaa
     6601 aacaaaatca ggaattgaga tacttgttca tgtaggaata gatacagttg agctaaatgg
     6661 tgagggattt gatattaaag ttcaagaagg acaaaaagtt aaggctgggg atattcttat
     6721 gaccattaat tttgtagttt ttgaaaagaa tcacaagact aaagatgtca ttgttgtttt
     6781 tccagactac caagacgaaa ttttcattcc gaaacttgaa gaagtaaaac aaggacaaga
     6841 attgtttgtt cttggctaat gataagtaat taataataga atcgaggaaa atgtatggtt
     6901 tttggggcta ttgaagctgg tggaacaaaa tttgtttgtg ccattggaga taaagatttg
     6961 aacatatttg aaaaagtcag ctttcccacg actacaccca aagaaacaat gaatttagtt
     7021 ttagattttt ttaatcatca taaagatgat ttagaaggta tcggagtggg atcgttcggt
     7081 cctattgata ttcattgtga atctaaaacg tatggcttca ttaaatcaac gccaaaactt
     7141 gcttggcagg attttgattt tattggaagt ttaaaaaagc aacttaatat tccaactgct
     7201 tggacgactg atgtaaatgc ctcttgctat ggtgaatatg tttctggaaa tggcagaggc
     7261 ctttcaagtg ttgtttacta taccgtagga acgggcatag gaggtggcgc tatccaaaac
     7321 ggaaacttca ttgaaggttt tagtcatcca gaaatgggac atatgcttgt aaaacgacac
     7381 aataaagaca acttttctgg gacatgtcca ttccacggag actgtttaga gggcttagct
     7441 gctggtccgg caatcgaaag aagatcaggg aaaaagggac aagaagtgac tgaaaatgac
     7501 gttacttggg aaatagaagc ttattacatt gctcagtgtg catataatac aacattgatg
     7561 ttatcacctg atgtcattat atttggtggc ggagtaatga aacaaaaaca cttaaaaaag
     7621 aaagtacaag ataagtttat tgagttgatc aacggatatg tcgctattcc cgatgttgac
     7681 aattatatta tgacaccaaa attgttagat aattctggta ttgtaggttg tttagcttta
     7741 gcaagagacg ttaaagaaaa atcttaattt ggaaaaaaga tcgtctcgac tatttgtttg
     7801 gttgatgcga tctttttttc aattagtaat tgaagggacg cctaaaagtg aaaaaaaaaa
     7861 tgaaagatga agtattagag tatatcaaaa ataatttaaa gtattacgat ttttctgctc
     7921 aagatattgc aatgaaattt tgtattaaaa gaaatgtcgc ttcccactat ttgaatcagt
     7981 tattttcaga tggaaaatta ctaaagaatg attctgttag accagtaatg ttcaagtata
     8041 atcaacaaaa gccaaaagac tgcttttcta agtttattgg agcagacata tctttgaaat
     8101 ccactataga taaatgcaaa gctactgtaa tgtatccccc taatggcctc ccattaataa
     8161 taaaaggaaa cagtggcgtt ggaaaaagtt ttttagcaag tttgatctat cagtatgctc
     8221 ttgatagaaa agtaattcat aatgacgcaa aatttgttgt tgtgaattgt gcagattatg
     8281 caaataatcc agagctattg tcagcagttt tatttggata taaaaaagga gcctttactg
     8341 gggctgaaaa agatactgca gggatgctat cttctgctaa tggaggatac ctttttttag
     8401 atgaggttca caatctaagt gcagaaaacc aagagaaatt gtttcttctt atggattctc
     8461 aaaagtatcg taaacttggt gaaagtgtgc aatgggagta tgcaaatgtt cgccttatct
     8521 tagccacaac agaagataaa aatacctctt tgttagcaac ttttagaaga cgcatcccag
     8581 ctgaaatcac tctgccagat tacaataata gaagtacatc tgaaaaaatt caattattat
     8641 ttgaatttct taaagatgaa gcaattacga ttgattcaaa aatattttgt tcgattgaac
     8701 tttttactga tcttttatcg aaaacatttg aaggaaatgt tggagaattg aggaatgaaa
     8761 tcaagcttct ttgtgcagaa ggttatttag gaaataagag aaagtcttca atttatttag
     8821 gggacaaact agacagcggt ttttggatag atccagaaat tagtatagat ttaaaaaaaa
     8881 tgtttcttaa atcactttct gaaattgatt tgattgaact ttttcaaaat cacatttcaa
     8941 ttgaagaaag catgagtcaa ttaagagata gaatacttaa agagtgtgca ggttcttctg
     9001 agtataatta tttagaaagt gacgaattta tagcattaag aaactatgtt gttaataaaa
     9061 tatcaccaat tattgattcg acaggtctat gtttattaga tgaattcttg gcggatatca
     9121 gtctatttat aatgtttatt gatgtaattg aagaaacatc aagaaatttt ttgctgtcta
     9181 agttcagaaa atttcgtatg aaaaatgata aacaaaaatt attggcaaat gagatttgga
     9241 gtagtttaga agtcgaagaa agtaaacaag aacttttgtt gaaatggata ctttttcttg
     9301 taaagaagtt ctatgtgaaa ataccagaaa cccattgtct gatagttatg cacggtaaaa
     9361 taacagcttc tgcgatcgca agggaaacaa ataagttgct gaatacatat gtttatgagg
     9421 ctttcgatat gccaattgaa ggtgagacta gtgacttaat taacctaatc aacaattttt
     9481 gtaaaagtat agatacgacg aatggactca ttctgctagt tgatatggga tcattggaac
     9541 aaatgtatga aaaaattgaa tccaatgtaa taggtgattt ggtaatttta aacaatgttt
     9601 ctacagcttt agcgattgaa tgtgggattc aagtttgcca aaaaaagcca attagtcatt
     9661 tttaccagat ggattttgat tcgtttcaag ttaaagttca gtattataaa ggattatcac
     9721 aaaagaaaaa tgtaatagta tcttgtctct ctggtgaggg gatttctgaa aaagttaagg
     9781 atattttaaa acggtatctc gataatcaag tggagatttt gatttttgat tttaacgcat
     9841 taaagaaaat agcaaaggaa aaagatacta tgatttttaa gaatacaatt tgtgttcttt
     9901 caaccactga attttacatt caaggaatcg attgtttaaa tttagaaaat ctaattaatg
     9961 ggaatcaaac cttagaaaaa ttaaataagt atatggactc ggatagctgt gagttctgct
    10021 taaatgaatt agttaaactc tttactattg aaggcgctag tactaagctt cgctttttag
    10081 attccaaaaa agtattcaat gagatagaaa aagtactata tttgtatgaa aaatattacg
    10141 atgtcaaaat cccaagtttt ctgagaatta atctatttct acatctttct ggaatgattg
    10201 aacgaattat gattggtgat ggaataacaa atgaacattt gaaagaggga gcgcaactat
    10261 ttgatacttt tttaaatgta tcaaaagatt ttttttcaga aatcaaagat atttactgta
    10321 ttgaaatacc caaaggagag tatgagttaa tctatacaat ttttgagcag actattttct
    10381 aaatagcata ctagcgtcta aaaaaatgaa agggtgtcca aagtatattt agacgctcat
    10441 ttaattaata tttactgtat tttcccgctt tattggataa tgttagttgg cacagtaatt
    10501 gcttatataa aagtataaga agaaaggaga gaacaaaatg gcgttttggc aaacattttt
    10561 agttgtgttg tatggatttt tcattaactg ggataaggaa gggcccaaaa tcggaacctc
    10621 ccaacctgtc gttgcaggtt tcttgaccgg acttattatg ggagatattc aaactggact
    10681 ttatatcggt gggactttgc aattaatgac actaggtatt actagttttg gtggtgcatc
    10741 agtaccggat tatcaaacag cagcattgat cggtacttat ttagcaatct caactaacca
    10801 ggatgcttct ataggaataa ctttagcaat accggtagca atgttaattg tacaactaga
    10861 tgttctaaag tggtcaacaa acattttttt tcaacaaaag gcagaaaaat tcgcacaaaa
    10921 agaagattat caaaaattag agtggatgca atatttggca tcaattaata caagctttgt
    10981 atctggaatt cctgttttgt taactgtgat attaggccca acgttagtgg gaagtgcaat
    11041 caattatatt cctgaatggg ttaccggtgg tttaaaggta gcagggggac tattacctgc
    11101 tgttgggata ggaatgctac ttaaatattt acctacaaaa gattactttg cctatttgtt
    11161 agttggtttc gttttggcag tttatttcca aataccaatt ttagggattt cgttacttgg
    11221 cgctgcaatc gcactaatcg tatataaaaa tagatcaaat aatactcaag tagcaccagc
    11281 tgcaacagga ggttttgacg aagatgaata agaaactgac aaaaatcgac aaacaagtaa
    11341 ttttccggtg gattctcaat ggtgcaactt cattaaatta tgaaaaaatg gaagggttgg
    11401 gttatgcgta ttctatgctt ccttttatca aggacacata taaagatgat cctgaaggaa
    11461 tgaaacaatc cgttttagct cacttacaat tttttaacac tacgccgtat acagcgcctt
    11521 acattattgg tatgaatgtt ggaattgaaa aagaagaaaa aaataagtct ttggaagcag
    11581 taagtgctct gaaaacaggt ctaatgggtc ctttagcggg aattggagat agtgtatttg
    11641 tagttattcc atggactatt tttggagcaa ttgcagctaa tatggcattg gaaggtagtt
    11701 ttgttggaat tattttgtgg atactggcat caattttatt aaggattact gcttatcctt
    11761 tataccttgc tgggaaagaa tcgggtgcga gcctactaac tcaaattgaa acaaaattaa
    11821 agtctattac tgatgcagta tcaattttag ggttaatggt ggtcggtgca ctcattgcca
    11881 cagttgtaaa agtgaatgtt ggctttgaat ttaaacaagg cgacttaaca atgaccggaa
    11941 atgaaatctt tgatcaagtt atgcctggtt tattacctgc atgtgtagta gcaattgtgt
    12001 attatttgtt aggacgaaag gttaaaccag tttatgtaat tctattaatc ttagtagttt
    12061 ctattgcgtt aagagcgtta aatattttga agtaggtgtt gaatatggat gaaaaaatga
    12121 aaggtattat acatgttcgt attgatgatc gaatgattca tggacaagta gcaacacaat
    12181 ggacaaatca attgagtgct aacagaatta tggttattaa taatgaagta gccaatgatg
    12241 acgtaaaaaa agctgtagtt cgcctcgctg caccacctaa tgttagaact tcaataatta
    12301 caagggaagt agcagttaaa aatattcttt ctggtaaata tgaaggacaa aaagttctta
    12361 ttgttgcagt ttctccaatc gatgttaaat ttttgattga taacggttta ccaataacaa
    12421 gtgtaaacgt aggaaattta tcaagaagga atggaacaga acgcatccgt ccgacgataa
    12481 atattactga agaagagaga gaggctttta aagaactaat tagtgatgga gttgaagtga
    12541 cagtgataca aactcctaga gattcaaaag aatttttaaa ggattttatt tattaagaac
    12601 agaggatgag tggatggagt ttataattac atctcatgga aatattgcca ttggatttgt
    12661 agatacatta aaaatgtttt ttggcgataa tttaaattgt catgtggtaa cacttggaga
    12721 tgcaggcatt gaagaattcc gtgaaaacat tgaaaaaata gtttctcaag taaaaaatca
    12781 agaagttatg gtatttgctg acttgattgg tggaacacct ttcaacgaat ttgctaaaag
    12841 aagtgaagta tttcaaaatg ggtttcaact tcttggtggc atgaatttag gaattttgat
    12901 tgaggctgtc aatttgagat tacaaggaaa aaaaagcgat gatatcatcg aaaatctaag
    12961 aaatatgaat acaattgcgt gtcttgcaga tatgcaaaga catactaacg aagaggatga
    13021 gtgataaatg caaaaaattt tttacaagcc taaagatttt tggtttgggg attgcatgcc
    13081 tttttataaa gatggaactt tttatctatt tcatcaacga gatacgagaa atcctaaacc
    13141 tttaactgat ccttttgggt ggtcactagt tacaaccact gattttgtga aatttgaaga
    13201 atacggggaa gtaattcatc gtggtggcaa cgatgacatt gatcaataca tttacgctgg
    13261 aagtattgtc caaggaatca atgagtattt agctttgtat actggacata atcgcaaagc
    13321 taagttggat ggaaaaactt cagaagtgtt aatgattgca agttctaaag atttaattca
    13381 ttggaaaaag gatggcgaag cagcaaaact tgttcctcaa gaaggatatg ataagaatga
    13441 ttggcgcgat ccttttgcaa tttttgatca agatcatgga aaatacgttt tgatactagg
    13501 agctagaaaa ccagcaagta agaaaaagcc gacggggaga ttggtctatt ttgaatccga
    13561 agatttaaaa gattggaatt tcaaaggaga ctactgggct aataatgaat ttaacatgat
    13621 tgaaatgcct gatatatttg aaattgatgg aacgtggtat ttactttttt cagagtattg
    13681 tgaagataaa aagactaaat atcgagtcgg agcaggatta ttttcagatt ggaaatcacc
    13741 agtagacgaa gctttcgacg gaaaagccta ttatgcagca agaacagtcg gaactaatga
    13801 aactggccgt tttctaactg gctgggtggc aacaaaagaa ggggagaacg atcaaaataa
    13861 ctgggattgg ggcggtgcac ttgttccaca tcaaattatt caaaagacag acaaaactct
    13921 tggtgttaaa ctgcctgaaa aaataattga gaattttaaa gaaatcactc cattttcaag
    13981 ttttaagtta gagaaagaat ttggaaaaaa agaaagagta attgttccta aaatcgaaga
    14041 ttattttcta tttgaaacaa ctttgactat tacatcgtta acaaaggagt ttgctttaaa
    14101 attatttgta gatagtgata ctcaagaagg atacgaattt cgtatttcat tgattaataa
    14161 tcagcttact ttcggaaaaa ctccgaacta tccttggcct caaatgtttg ataaggggct
    14221 gcaacgacca ctatttttgg aaataggcaa agaatatgaa ctaaagttaa ttgttgatga
    14281 tacgatagct gttttatata ttgataatgt tgctttaagt actagaatgt atgataaagt
    14341 cggaacagca ttaagtatga ctgttacgga gggagcaatc aaggtagata aactagacta
    14401 ttcaataaat tatgaatgtg gattttaaaa caattgaagg gatgatgtaa gtgaaattaa
    14461 atggtttaca acatattgga attccaacaa aagattttgg agcttcaaaa atcttttatg
    14521 aatccttagg gtttagtctg attaatgaag aaatgaatgt gggaagtaaa gtcggctttt
    14581 tcgagttgaa tggaacgata atagaaatat gggaagataa aactactgag tgtagaggag
    14641 ccattgatca tctagcatta gatacggatg acatagatga ggtattcaat tcaattcaag
    14701 atttaggata tgaattatta gataaaaata ttatggaatt accgttctgg gaaaatggaa
    14761 tccgttactt taatttctac ggaccaaatc atgagattat agagataagc caaatgaaga
    14821 aataaataga taacgaagtg ctctaagttg gtatgaacga aaagtacttc attttttggt
    14881 atcagcattt caatagttta atgagaattt actatttcaa attaattcaa agtgacagta
    14941 ttttttactt atttggtttc aaattttgta atccttccta tttattggaa tacactccac
    15001 attttgtata caagtcatat catgttttag caaagctctt accaagcaaa gttataatga
    15061 tgttttccaa agtttgatct ttcgatggag gctaacacat attttttgca ggacagccaa
    15121 aattagatgt atagaataga gtctgtgagg cgtatagaca gtttattgtc tgtatgcctt
    15181 tttttatttt gaaaaatttt tagtattttt cgaaaaatgc tcactcctag
//
LOCUS       DAFLWC010000072        14820 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.073, whole genome shotgun sequence.
ACCESSION   DAFLWC010000072 DAFLWC010000000
VERSION     DAFLWC010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14820
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.073"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(296..1024)
                     /locus_tag="L1V17_002150"
     CDS             complement(296..1024)
                     /locus_tag="L1V17_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="HBN1236900.1"
                     /translation="MLRIAIVDDDCTIVEGIRHYLLKKVPDIIIDHCYTDGDEAFKNL
                     QNQRFDLLITDITMGKISGLELIESLQQTSNRYFTSIVISAHQNFQYAKKGIDLSIKS
                     YITKPIDFPYLVKLVQEEKMRKSAANQNSLTDDSFNESIQQVIDYVQNNYSEKLTLKD
                     VATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGIDH
                     VSYFSVLFKKTTGHSPSNYRKKLL"
     gene            complement(1002..2576)
                     /locus_tag="L1V17_002151"
     CDS             complement(1002..2576)
                     /locus_tag="L1V17_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBN1236901.1"
                     /translation="MKNDLSKVIMRFTYILIFFITLLACFTLFFSYINVIEKEKNQNL
                     QNIQQITHYMETYNRILSGIVTEIYQNYDFQENLNDYYLSSPAEYMEDILSKDRSPTY
                     LVDNLKKLVQDDEVKNISISLDYEKYLSAYAPTKNEKISFIRSLSFISEDMPDATLIL
                     DVSINALKKSLFPTHYNYSLSNGIDSVNLSEDISPSKWKKTQQIAIGNHTLQVYENPN
                     YSSQTLLGLAIMIFLLMSLFILAIHQLLNRSFRNYIQQYQEIITSLNHSSTGDYKSIN
                     IENKVGDLKEIAMHINQFYLDNATYQKTLYENNWLKQEAKYAALQYQIEPHFLFNNLE
                     FIRMTAILNDDEEISDSIYLLSKLYRNNTYQPDIIDLKEELINIDLSLQLHQRRYRHN
                     FDYQLIDHIDQLMLPKLSLQPFVENYIKHGFDSSKKENRLTVYATETTNHYVLKIVEN
                     GKGMDQDKLEHIQQKLNDDIPYSENIGISNSFRRIKHLYPGDTRFVIESQLHVGTTIT
                     IKIQKGGNMHVENCNC"
     gene            2805..3743
                     /locus_tag="L1V17_002152"
     CDS             2805..3743
                     /locus_tag="L1V17_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1236902.1"
                     /translation="MKLKKGLLGNLKKNRALFIMLLPGALWLFIFCYIPMFGVVIAFK
                     DFRISSRGFFTSLFNSPWVGWENFKYLFASQDAWIITRNTVVYNVVGILLSTFCTVSL
                     AIILSQMANKRLLKKMQTFMIFPNFLSWVVISYFVYAFLSTDKGLINILLSNFGVEPI
                     NWYSEPKYWPFIIVFTSLWKGVGYGSIIYYASIMGIDTSYYEAALVDGASKWQQIRNV
                     VLPHLRSIIVIMLILSVGSIFRADFGLFYQLPRNSGALYDVTNVLDTYVYRGLMNSGD
                     IGMSTAAGLYQSSVGFVLILITNKIVNKLDPSSALF"
     gene            3755..4666
                     /locus_tag="L1V17_002153"
     CDS             3755..4666
                     /locus_tag="L1V17_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1236903.1"
                     /translation="MISKLKRQMYFSLPVERFFTILLILFTLSCIFPFIFVIVISLTD
                     EKALQLNGYELLPAQWSTDAYQYLIQDGGQLLRSLGVTIMITVIGTLITVFMTGTYAY
                     VLSRASFPYRKFFTFYLFFTMLFAGGMVPSYLVMTKMLGLKNTIWALILPLAFSPYNV
                     IILRTFFKKSIPESIIESAKMDGCSEFRVFFQIVLPLAIPGVATIGLFSSLGYWNDWF
                     NALLYIDTNKLIPLQYLLMKIQNSMEFLANNNDITLAQQQAIQNSLPQESTRMAMVVV
                     ATLPIAIVYPFFQKYFVQGLTIGGVKE"
     gene            4690..6162
                     /locus_tag="L1V17_002154"
     CDS             4690..6162
                     /locus_tag="L1V17_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBN1236904.1"
                     /translation="MKKNMQKYLIGGASVLTLGLLGACGSSNGEANNETGTTKVTWYQ
                     VGEEPKDFDEVMTKVNEKLKEEINVELDMRLIPDGDYQQKLGVMINSGEEYDICFVNG
                     TDYVNYGNKGAFISLNDHLDKELKDYAAELNEGFIEGGAINGETYGLPVNNDIATTEY
                     WTFNKDLVDQYQLDVENVEGVETLAPVLEKFAEKNTDTNITPIGMTRTSVCIPYDNII
                     GGGVPLAVAFEGDTQTVVNTYETPEMMTYLKAMHEFYKKGYILKDAATVTTDPFRIDS
                     KNWFLGRNSSGYQPLAQKKLEALAGHGLILKPAGKAFKTTGFARVAMHAVSASSKHPE
                     AALKLLNYVNTNQEVADLMVYGIEGKHYDRNEDGSITLTNSDDYYQGAWALVNTYLVS
                     KTSPITEESKKLEEESKKFQNEAPMSPILGFSFDASDFRTEIASVQNIVSQYEVLLSS
                     GTVDPEQYVPELLEKLEKAGLDKIQASAQEQYDEWRKSNK"
     gene            6213..6824
                     /locus_tag="L1V17_002155"
     CDS             6213..6824
                     /locus_tag="L1V17_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBN1236905.1"
                     /translation="MNENKWTKGFNWVFQLLLLNFTYFILICLGFGILGFFPATIALI
                     AGVVNRKKYGLQESVKFMSKIYKKNFVRYNLYCWSATLLLAGNITTIWLCWQQSAPLF
                     YLLSTLLSVITLFLVFAMLNWVVIKSLGLWMMGDRLIDYLLFTATMLPTVVMQGLVLG
                     IYFRILMILPVIFLFGGTAVTVILISKLTERALAKLPCQIQSH"
     gene            6854..8767
                     /locus_tag="L1V17_002156"
     CDS             6854..8767
                     /locus_tag="L1V17_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 20 glycosylhydrolase"
                     /protein_id="HBN1236906.1"
                     /translation="MKLTDKQVANIAFIQQLEIPLTQKDEEQIDLIFTDTKANVRQIK
                     ITKNEQQRICLSYSHEDLLYRGLFICLPRFLAQGGEMPYIEETSIIETSYSLDASRNG
                     VMNKETLKKFISYLALMGYNTLYIYTEDTYEVEDLPYFGYLRGAYTKEEVNEIVEFAS
                     GFGIEVVPSIQTLAHLTQFLKWYAQQELMDDQNTLLIGEEKVYAAIEKMIIACKEMYQ
                     TERIHLGMDEAYQAGLGRYLSLYGYCDRTTLMIQHMDRVLSIVDKYKMKPMIWSDFIY
                     KLLDETGKDRYYNPDFKLKALAAKGLPAGLTYVHWDYGSDEVSSYEKVIDNHLKFCDI
                     DHYVLASGAHIWGRLAPNHGKTEAIVSAAVKASKNKGVRSVMLTTWGDEGQETEHWHS
                     LIGALKLADYVYSEEEWNDFEEIYDRLLGTGSYQLMSELRYFDEVDTITNNNLQMASV
                     SKLLLWQDPLVGIYDFHVAAHNKIATRTIGTYYHELAQKLDMNKNWNPKQPILTTIRQ
                     RYILLAEILAQKAELGIYLQHCCLVEDLAGLMELANRCEALANRVNELASIHEIIWYQ
                     TYKTYGWEVLEQRYAALAHRLKTVARRIKNHLQGQDALEELLEERLPFCQYQVPLEIS
                     GFNYRQSSVSGYN"
     gene            8895..11876
                     /locus_tag="L1V17_002157"
     CDS             8895..11876
                     /locus_tag="L1V17_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 42"
                     /protein_id="HBN1236907.1"
                     /translation="MLSDYYQNLSVISVNTEPLRNYYIPYASKEEAKQELEREKTSQF
                     IDLNGTWDFQYYPSVQQLPENFFQEAFTESYDRISVPGVWQTEGFDLPQYINVSYPIP
                     FDPPYVPNDTPCGVYRRQFQIEQTDARFYLNLEGADSNCFVWINRNFVGYDQVSHSTS
                     EFDVTKYLQVGVNEIQILVMKWCDGTYFEDQDKWRMSGLFRPVYLLQRPTMHLTSYQL
                     RTLTDPKKGSGTLMVSFQRFTPIEVSLPISYELFHPDGRLIAKGECYSEQQINLDVED
                     CLFWTAETPKLYTLLLTCNGEYFKEKVGFRALTIKNRKLLLNGTPIKLYGVNYHDVNQ
                     QGTPVMTREQLRADLLLMKKLNVNTVRTAHYPKSPDFYELADEIGLYVINEADLECHG
                     VVNLYDTEANYQLIANDPTFEKPIMDRVIRSILPYQNRSSIIMWSMGNESGYGVNFEK
                     AQALARKLDDSRLIHNERSIEPVIDQVNDFSNLDVISQMYPPLEDVHRHCQRSDTEKP
                     FFMCEYSHAMGNGPGDLKTYFDLIQQYDSFLGGCVWEWTDHAINRGTLETPSYLYGGD
                     FGEKYHDGNFCVDGLLTPDRQLTVGALEYRNIHSPIQLIAVDEELQEVTLSNITAFTA
                     GSAFNLSLEWYIDGKKTVYEVMNPFILEPGKSCSLPITVPTTIHGAHTVAVSLSVYKN
                     DELYGQQQLFLKKEKMRLPRTAHHNDAPQISVKGTELIIKGESFIYIYQLAKAAFTSV
                     KINQKELLERPTQFSIWRAPTDNDRNLVNKWKAAGYAEMSLEIRKKDWKFVDDHLLIE
                     TSYRGVIPGLQPIFTMHIQLKINGAGVINQKVSVEKNPIFPDFPRFGMDWPLNDTFSK
                     VSYCGYGPYESYPDKHYAAMFGIYEMEIEEFDQPYIKPQEYGNRWQCDWVSIKNHQGS
                     TMTVYGNSNFSALPYSQAQLTEKSHHYELIKENRTWFNLSYKQNGIGSHSCGPYLEDR
                     FRFMEDTFDWNIVITFKGENR"
     gene            11873..13534
                     /locus_tag="L1V17_002158"
     CDS             11873..13534
                     /locus_tag="L1V17_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HBN1236908.1"
                     /translation="MKETKINQVKKKLSRYQEVVYRNHCLKWSKNKLNVRFNGLFYRF
                     EQLEEVWKPVTNFQSCPVQLINDPKETYDLCITHLYNQHLKNDGFYLKVTNDNQLTIE
                     SANLRGFQYAMEALLESFFSVGDQLLLPELILKHEPSVKIRGIIEGFYGIPWTHEMRL
                     SLFSYMKDNQLNTFMYAPKDDELLRKKWRELYDAQELDKFKELLSAAEASNIDFWYLI
                     SPGNDIDITCEEDIQVLLKKLEQLIELGVFQFGLLMDDIDYQLKGAAKRRFREPAFAH
                     AYLVNRVEEYLSTRLSNHELVICPTEYDNRHGSRYLATLSQEIPEQLPFFWTGPSTLA
                     ASISTEELQEMASVYQRPMLIWDNIPVNDYLEDKELLFMSPYENRTPNLSKERYQVTG
                     VVSNPMAQLEASKFTINSMANYLWNCERFDPLETWTSVVEKVVGSKLQPAYLTLTNAF
                     PNHYTSSLLSDEELLLAKDPEWVTKEMAALVQAVKWIQQEQHTSRLRTELEPWLQAIT
                     ESWTFWQEWQLKKDPKEAEEWLAKKKTHRIGRDLVTAHLEQIIKS"
     gene            13574..14506
                     /locus_tag="L1V17_002159"
     CDS             13574..14506
                     /locus_tag="L1V17_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HBN1236909.1"
                     /translation="MVKRLISANYSDVKKMTSKELKQSIKASEGRVIVCETVANTLPQ
                     SGEITNAEVASAFGADLILLNGFDCYRPAVFGLPNVTIEKVFDLQQTIENPIPKLKEL
                     VGRPVGINLEPIAPKTNMMSEKVEISQGRASSVETIQKAEELGVDFICFTGNPGTGVT
                     NLEITKSVKMAKKYFSGLIIAGKMHSAGSEEPVVNKEAIISYAEAGADILLVPSVGSI
                     PGFLEQDLIEAVRLAKKYDLLTMSAIGTSQESARPETLRQLAIMNKSCGVDLQHIGDA
                     GYGGLAPAENIFETSVAIRGMRHTINCVSRSINR"
BASE COUNT         4818 a         2333 c         2979 g         4690 t
ORIGIN      
        1 atttaaataa ctacatccat ttattctatc ttctaaaata gcctttttca tttcagttaa
       61 atagttcagc gccatttttg cactcgactt gcatagtagt tttttccata ttcctcaacc
      121 tcagcggggg ttgaagacat aaggaaaatc ctatgcgtta tgctcaactg gatctgatta
      181 aatattctaa tgtatttttc tctaccatca ttaaatggtt aatagccaaa aatcaccact
      241 tttcaatggc tccttgttgt ataagtataa ctagaagatg aacacgtctg agaaattata
      301 gaagcttttt acggtaatta ctggggctgt gtccagtagt ttttttgaag agaacagaaa
      361 aatagctcac gtgatctatt cctacttttt gactaatttc atcaatagat aagaatgtgt
      421 ctttcagtag agcacttgct cttttgattc gaaagtctag caagtaatca tgaaaggaat
      481 aacctgtttc ttttttgaag gcccgtccta aataagcggg atggtaatgg aattgtgtag
      541 ctacatcttt gagcgtaagc ttttcactat aattgttttg aacgtaatca atcacttgtt
      601 gaattgactc attaaaagaa tcatcagtta gagagttttg attagctgct gatttacgca
      661 ttttttcttc ttgtactaac ttaactaaat aaggaaaatc aatgggtttc gttatgtaac
      721 ttttaataga taaatcaatc cccttttttg catactgaaa attttggtgg gcactaatga
      781 caatactagt aaagtagcga ttggatgttt gttgcaaaga ttcgattaat tcgagtccag
      841 aaattttccc catcgtaata tctgtgataa gtaaatcaaa gcgctggttt tgcaggtttt
      901 taaatgcttc gtctccgtct gtgtagcagt gatcgataat gatgtcgggg actttcttca
      961 aaagataatg ccttatgcct tctacaattg tacaatcatc gtcaacaatt gcaattctca
     1021 acatgcatat tccccccttt ttgtattttg atagtaatcg ttgttccgac gtgtagttgg
     1081 ctttctataa caaaacgtgt atctccagga tagagatgct ttatacgtcg aaaagaattt
     1141 gagatgccga tattctcact ataaggaata tcatcattaa gtttttgttg aatatgctcc
     1201 agcttgtctt ggtccattcc tttcccattt tcaacgattt ttaacacata atggttggtt
     1261 gtttcagttg catagacagt caaacgattt tccttttttg atgaatcgaa gccgtgttta
     1321 atataatttt caacaaatgg ctgtaaagaa agttttggta acattaattg atcaatatga
     1381 tcaatcagct gatagtcaaa gttatgtcga taacgacgtt gatgtagttg caaggagagg
     1441 tcgatattaa ttaattcctc tttcaaatca attatgtcgg gctgatatgt attattgcga
     1501 tacaacttgc tcaataaata tatactgtcg ctgatttctt cgtcatcatt caatatggca
     1561 gtcattcgaa taaattccaa attattaaat agaaaatgag gctcgatttg atattgaagt
     1621 gctgcatact ttgcttcttg cttcaaccaa ttattttcat aaagtgtttt ttgatatgta
     1681 gcattatcta aataaaactg attgatatgc atagcgattt ctttcaaatc accgactttg
     1741 ttttcgatat tgattgactt gtagtctcct gtagatgaat gatttaagga agtaatgatt
     1801 tcctgatact gctggatata gttacgaaaa cttctattta ataattgatg aatagcaaga
     1861 ataaacaaac tcattaataa gaaaatcatg attgccagac ctaataaggt ttgtgacgaa
     1921 taatttggat tttcatatac ttgtaatgtg tggttaccga tagctatctg ttgcgttttt
     1981 ttccatttag aaggcgagat gtcttcagat aaattgacgg aatcaatacc attagacaaa
     2041 gaataattgt aatgtgttgg aaagagactc ttttttagcg cgttgatcga aacgtctaga
     2101 atcaatgtag catcgggcat gtcctcacta atgaaactta atgaacgaat aaaagaaatt
     2161 ttttcgtttt ttgtaggtgc gtaggcactt aagtattttt cgtaatctaa tgagatagat
     2221 atatttttaa cttcatcatc ttgcacaagt ttttttaagt tatctactaa ataggtaggg
     2281 gagcgatcct ttgacaaaat atcttccatg tattcagcag gtgatgagag gtagtagtca
     2341 ttaaggtttt cttggaaatc ataattttga tagatctctg tcacgatacc ggagagaata
     2401 cgattatatg tttccatata gtgggtgatt tgctgaatgt tttgcaggtt ttgatttttt
     2461 tctttttcaa tcacattgat ataggaaaag aacaatgtga aacaggcaag taaagtaata
     2521 aaaaaaatca atatgtatgt aaaacgcata ataacttttg ataaatcgtt tttcattcaa
     2581 agtcctcatt ttgataatct ctaattttat gaatcattat agcacatatt acaagtgatg
     2641 taaacgcttt gcaaacaggg ctacttatga ttgtgaatac agtttccgtt taaaaactat
     2701 tctattgtag aggtttaata aactaaaaat aatgtataaa aaattaatgt aagcgattaa
     2761 ccaagtgggt ataatcaagg aaacgctgag agaggagaga caaaatgaag ctaaagaaag
     2821 ggttattagg aaatctaaaa aaaaaccgag cattgtttat tatgctttta ccaggtgcgt
     2881 tatggttatt tatattttgc tatataccaa tgtttggagt tgtaatcgct tttaaagatt
     2941 tcagaatttc atcaagggga ttctttacaa gtttgttcaa cagtccttgg gttggctggg
     3001 aaaatttcaa atatctcttt gcttcgcaag atgcttggat cattactcgc aatacggttg
     3061 tttataacgt tgtaggtatt ttgctaagta ctttttgtac agtgtcatta gcaatcattc
     3121 tgagccaaat ggcgaacaaa cggttattga aaaagatgca gacatttatg atttttccta
     3181 attttttatc atgggtagtc atcagttact ttgtttacgc atttttgagt acggataaag
     3241 gattaattaa tattttacta agcaattttg gtgtggaacc cataaattgg tatagtgaac
     3301 cgaagtactg gccttttatt attgttttta cgagtttatg gaaaggcgta ggctatggat
     3361 ccatcattta ttacgcgtca attatgggga tcgatactag ttattatgaa gctgctttag
     3421 ttgatggtgc cagtaaatgg caacagataa ggaatgtagt cttgccacat ttaagatcga
     3481 ttattgtcat tatgttgatt ttgtctgttg gtagtatttt tcgagctgat tttggattgt
     3541 tttatcaatt gccaagaaat tcgggggctc tttatgatgt gacgaatgta ttagatactt
     3601 atgtctaccg tggattaatg aatagcggag atatcggaat gtctacggca gcgggattat
     3661 atcagtcatc agttggcttt gtcttgattt tgattactaa taagatagtc aacaagttag
     3721 atcctagttc agcactattt taggaggaat caaaatgata tcaaaattaa aacggcagat
     3781 gtacttttcg ctgccagtcg aacggttttt cacaatatta ctaatcttat ttactcttag
     3841 ctgtattttt ccctttattt tcgtaatcgt catttcatta acagatgaaa aagcattaca
     3901 actcaacggt tacgaattat tgccggctca atggagcact gatgcatatc aatacttaat
     3961 acaagatggc ggacagttac ttcggtcatt aggcgttaca attatgatta cagtgattgg
     4021 aacgttgatt actgttttta tgacgggaac ctatgcttat gttttatcaa gagcctcttt
     4081 cccttaccgg aagttcttta ctttttatct tttttttacc atgttatttg cgggagggat
     4141 ggttccttct tacttagtga tgacgaagat gcttggctta aaaaatacaa tttgggcttt
     4201 gattctacct cttgctttta gcccatacaa tgtcattatt ttaaggacat tctttaagaa
     4261 gtcgattcca gaatcgatta tcgaatccgc taaaatggat ggctgtagtg agtttcgagt
     4321 ttttttccaa atcgttttgc ctttagcgat cccaggggtt gcaacaatag gtttattttc
     4381 aagcttaggt tattggaatg actggttcaa cgcattgctg tatattgaca ccaacaaatt
     4441 gattccattg caatatttgt taatgaagat tcaaaattca atggaattct tagcaaataa
     4501 taatgacatt acattagcgc agcaacaagc aattcaaaat agccttcctc aagaatcaac
     4561 acgaatggca atggtcgtag tagctacttt accgattgca attgtttatc cgttcttcca
     4621 aaaatacttt gttcaaggat tgacgatcgg tggagtgaaa gaataaaaaa gaataggaga
     4681 tgttaaaaga tgaaaaagaa catgcagaaa tatttgattg gtggtgcttc tgtactaacc
     4741 cttggcctat taggtgcttg tggtagcagt aatggcgaag caaataatga aacaggaacc
     4801 acaaaagtta cttggtatca ggttggagaa gaacccaaag attttgatga ggtcatgaca
     4861 aaagtcaacg aaaaattaaa ggaagaaatc aatgtagagt tggatatgcg gctgattccg
     4921 gacggggatt atcagcaaaa gcttggtgtg atgatcaatt caggagaaga atatgatatt
     4981 tgtttcgtca atggcacaga ttatgtgaat tatgggaaca aaggtgcttt cattagtctc
     5041 aacgatcatt tggataaaga gttgaaagat tatgcagctg aattgaatga aggatttatt
     5101 gaaggtgggg caattaatgg cgaaacttat ggattgccag tcaataacga tattgccaca
     5161 acggaatatt ggacctttaa taaagatttg gtagatcaat accaattgga tgtagagaat
     5221 gttgaaggtg tagaaacatt ggctccagta ttagaaaagt ttgcagaaaa aaatactgat
     5281 acgaatatta cgccaatcgg tatgacccgt accagtgtct gtattcctta tgacaatatt
     5341 atcggtggtg gtgtaccgct agcggttgca tttgaaggcg atacacaaac agttgttaat
     5401 acttatgaga ctccagaaat gatgacttat ttgaaggcta tgcatgagtt ttataaaaaa
     5461 ggatatattt tgaaagatgc agccactgtt acgacagatc catttcgaat tgatagtaaa
     5521 aactggtttt taggtcgtaa ctcaagtggt tatcaaccat tagcacaaaa aaaattagaa
     5581 gctctagcgg gacatggatt aattttaaaa ccagctggaa aagcttttaa aacgactgga
     5641 tttgcaagag tggcaatgca tgcggtatct gcttcaagta aacatccgga agcagccttg
     5701 aaattgttga attatgtgaa taccaatcaa gaagtagcgg atttaatggt ttatggaatt
     5761 gaaggaaaac actatgatcg caatgaagat ggttcgatta ctttaacaaa ctctgatgat
     5821 tattatcaag gcgcttgggc attggtaaat acttatctag tttcaaaaac ttcaccgatt
     5881 acagaagaaa gtaaaaaact agaagaagaa agtaaaaagt ttcaaaatga agcaccgatg
     5941 tctcctattt taggtttctc ttttgacgct tctgattttc gaacagaaat tgcaagtgta
     6001 caaaatatcg tgtcacaata tgaagtactt ttaagctcgg gaacagttga ccctgaacaa
     6061 tatgtaccag agttgttaga aaaactagaa aaagctggat tggataaaat tcaggcatct
     6121 gctcaagaac aatacgatga atggcgaaaa tctaacaaat aattttttac taaatgaaaa
     6181 gaatagacta agcagttagt ggggggattc aaatgaacga aaacaaatgg accaaaggat
     6241 ttaattgggt ttttcaattg ttgttactaa actttactta ttttatacta atttgtttag
     6301 gatttggaat tttaggtttt ttccctgcta cgatagcttt gattgctggc gttgtgaatc
     6361 gaaaaaaata tggcttgcaa gagtctgtga agttcatgag taaaatctat aagaaaaatt
     6421 ttgttagata taatctatat tgctggtcag caactttgtt gttggccggc aatattacta
     6481 cgatctggct ttgttggcag caaagcgcac cattgtttta tttattaagt acattattat
     6541 cggtaattac actgttccta gtctttgcaa tgttgaattg ggtcgtgatc aaaagtcttg
     6601 ggttgtggat gatgggagac cgactgattg actatttgct tttcacagca acgatgttgc
     6661 caacggtagt catgcaaggc ttggtgcttg gaatttattt ccgaatattg atgattttgc
     6721 ctgtgatttt tctgtttggc ggaacagctg taacggtaat attgattagt aaattaactg
     6781 aaagagcgtt agcaaagttg ccttgtcaga tacaatcgca ctaatttttt cacaaaaagg
     6841 agtatttctt tctatgaagt taactgataa acaagtagct aatatagcct ttatccagca
     6901 acttgagatt ccattgacac aaaaagatga agaacaaata gacttgattt ttactgacac
     6961 aaaggctaat gtgcgacaaa tcaagattac taaaaatgag cagcaacgaa tttgcttgtc
     7021 ttattcacat gaagacttgc tgtatcgagg attgtttatc tgccttccac gttttttagc
     7081 tcaaggagga gagatgccat acattgaaga aacctcgatc attgagacca gttattcatt
     7141 agatgcttct cgtaatggcg tgatgaataa agagactcta aaaaaattca tttcttactt
     7201 agcgttgatg gggtacaaca cattgtatat ttacacagaa gatacctatg aagtagaaga
     7261 ccttccatat tttggttacc ttcgcggagc gtatacaaaa gaagaagtga atgaaattgt
     7321 tgaatttgct tctggttttg gcatagaagt agttccatcg atccagaccc ttgctcactt
     7381 gacccaattt ttgaagtggt atgctcaaca agaactgatg gatgatcaaa atactctact
     7441 gatcggtgaa gaaaaggttt atgcggcaat cgaaaagatg attattgcct gcaaagaaat
     7501 gtatcagaca gagcgtattc atttgggaat ggatgaagcc tatcaagcag gtctgggacg
     7561 atatttaagc ctgtatgggt attgtgatcg gacaacttta atgattcaac atatggaccg
     7621 tgtgttatca attgttgata aatataagat gaaaccaatg atttggagtg atttcattta
     7681 taagctatta gatgaaaccg gtaaagatag gtattacaat cctgatttta aactcaaagc
     7741 attagcagct aaaggattac cagcaggatt aacctatgtt cattgggact atggttcaga
     7801 tgaagtttcc tcctatgaga aagtaattga taaccatttg aaattttgtg acattgatca
     7861 ttacgtttta gctagtggtg cccatatctg ggggagacta gccccgaatc atgggaaaac
     7921 agaagcaatt gtttctgcag ctgtaaaagc ttctaaaaat aaaggtgtac gttctgtgat
     7981 gttaactact tggggagatg aagggcagga aacagagcat tggcattcct taattggggc
     8041 attaaaatta gcagattatg tctattctga agaagagtgg aatgattttg aggaaatcta
     8101 cgatcgttta ttaggaacag gtagttatca attaatgtcc gaattacgat atttcgatga
     8161 agtggatacc attacaaata acaacttaca aatggcttcc gtgagtaaac tgctactttg
     8221 gcaagatccg ttagttggta tatatgactt tcatgtagcc gctcataaca aaattgccac
     8281 tagaacaatt ggtacttatt atcatgagtt agctcagaaa ttagatatga ataaaaattg
     8341 gaatccaaaa caaccaattt taacaactat tcgtcaacga tatatacttt tagctgaaat
     8401 tttagcacaa aaggcagaac taggcatcta tttacaacac tgctgtctgg tagaagacct
     8461 tgcaggatta atggaattag cgaatcggtg tgaagcacta gccaatcgag taaatgaatt
     8521 ggcatctatt catgaaataa tttggtatca aacatacaaa acctatggtt gggaagtatt
     8581 agaacaacga tatgctgcat tagctcatcg tctgaaaacc gttgcgcgtc gtattaaaaa
     8641 tcatcttcag gggcaagatg ccctagagga gcttttggaa gaacgattac cgttttgtca
     8701 atatcaagtg ccgcttgaaa tttctggctt taattatcgg caaagctcgg tgtcaggcta
     8761 caattaacga aggaatcttc ccgttgaacg gaccacttgc tcatctaatg ggaaagtggt
     8821 tcgttttcta ttcataagta gcttaccact aactctttta ttaagaagag aaaaaaagta
     8881 ggaagtgaga aaatatgtta tcggactatt atcaaaatct gtcagttata agtgtcaata
     8941 cagaaccatt acgtaattat tatattcctt atgcaagtaa agaagaagca aaacaagagt
     9001 tagaaaggga aaaaacgagc cagtttatcg atctcaatgg tacatgggat tttcagtatt
     9061 atccttctgt ccaacagtta ccggaaaatt tttttcaaga ggcctttact gaaagctatg
     9121 atagaatttc tgttcctgga gtttggcaaa cagagggatt tgacttacct cagtatatca
     9181 atgtatctta tccaattcct tttgatccgc cttatgtacc taatgatacc ccttgtggtg
     9241 tatatcggcg tcagtttcaa attgagcaaa cagatgcacg cttttactta aatctagaag
     9301 gagcagatag taattgtttt gtttggataa atagaaactt tgtaggctat gaccaagtga
     9361 gtcatagtac atctgaattt gatgtgacca agtatttaca ggttggggtt aatgaaattc
     9421 aaattctagt gatgaagtgg tgtgatggta cctactttga agatcaggat aagtggcgaa
     9481 tgagcggtct atttcgtcca gtgtatcttc ttcaacgacc aactatgcat ctgacaagtt
     9541 atcaactacg gacgttgact gatcctaaaa aaggaagcgg aacattaatg gtttcttttc
     9601 aacgatttac tcctattgaa gtatcgttac ctatttctta cgaattattc catcctgatg
     9661 gacgtctcat agcgaaaggg gagtgttact cggaacaaca aataaatttg gatgttgaag
     9721 attgcctttt ttggacagca gaaacgccta aattatatac attactttta acatgtaatg
     9781 gtgaatattt taaagaaaaa gttggctttc gagcactgac gatcaagaat cgtaagttat
     9841 tgctgaacgg aacacctatt aaattatatg gagtcaacta tcatgacgtg aatcagcaag
     9901 gcacgccagt gatgacccga gagcagttac gtgcagattt gttattaatg aaaaaattaa
     9961 atgtgaatac tgtacgaacg gcacattacc ctaaatcacc agatttttat gaattggcgg
    10021 atgagattgg tctgtatgta atcaatgaag cagatttgga gtgtcatggt gtggttaatc
    10081 tatatgatac tgaagcgaat tatcaactaa ttgctaatga tccgacattc gaaaagccga
    10141 ttatggaccg agtgatccgt tctattcttc cttatcaaaa tcgaagctct atcattatgt
    10201 ggtctatggg gaatgaatct ggttatggag taaattttga aaaagctcaa gctttagcac
    10261 ggaaattgga tgattcacgg ttgattcata atgaacgctc gattgaacca gttattgacc
    10321 aagtgaatga ttttagtaac ttggatgtta ttagtcaaat gtatccccca ctggaagatg
    10381 ttcatcgtca ttgtcaaaga agtgatactg aaaaaccttt ttttatgtgt gaatatagcc
    10441 acgctatggg caacggtcct ggagatctta aaacgtactt cgatttgatt caacagtatg
    10501 attcctttct tggcggttgt gtctgggagt ggactgatca tgcaatcaat agaggaactt
    10561 tagaaacgcc atcttattta tacggtggtg attttggtga aaaatatcac gacggcaatt
    10621 tttgcgtaga tggtttattg accccagatc ggcaattaac agtaggtgca ttggagtacc
    10681 gtaatattca ttcgcctatt caactgattg ctgtagatga ggagctgcaa gaagtaacct
    10741 tgagcaatat aactgctttt acagccggtt cagcatttaa cctttctctt gaatggtata
    10801 tagatggaaa aaaaacagtt tatgaagtaa tgaatccttt catacttgag cctggcaaaa
    10861 gttgttcatt gcccatcaca gtacctacaa cgattcatgg tgctcatacg gttgctgttt
    10921 cgctatctgt ttataaaaat gatgagcttt atggacagca acagctcttt cttaaaaaag
    10981 aaaaaatgag attgccaaga actgctcatc ataatgatgc accacaaatt tcagtaaaag
    11041 gcacagagct gataatcaaa ggagaatcct ttatttatat atatcaatta gcaaaagctg
    11101 cgttcacttc tgtaaagatc aatcaaaagg aacttttgga acgtcctact caattttcaa
    11161 tttggcgtgc accaacggat aatgatcgta acttagtaaa caaatggaaa gcagctggat
    11221 atgctgaaat gtctttagaa atcagaaaaa aagactggaa attcgtagat gatcatctcc
    11281 tgatcgaaac gtcttatcga ggagttattc caggattaca gccaattttt acaatgcaca
    11341 tacagttgaa aataaatggt gcaggcgtaa tcaaccaaaa agtatcagtg gagaaaaatc
    11401 cgatttttcc agatttccct cgctttggga tggactggcc gttgaatgat actttttcga
    11461 aggtttctta ttgtggctat gggccgtatg aaagttatcc tgataagcac tatgctgcga
    11521 tgtttggtat ttatgagatg gagattgagg aatttgatca gccatatatc aaaccacaag
    11581 aatatggtaa ccgctggcaa tgtgattggg tatcaatcaa aaatcatcaa ggatctacca
    11641 tgacggttta tggaaactct aatttttctg ctctgcctta tagtcaagct caattaaccg
    11701 aaaagtcaca ccattatgaa ttaataaaag aaaatagaac ttggttcaat ttaagttata
    11761 aacaaaatgg tatcggctca cacagttgcg gtccttattt agaagatcgt ttccgtttta
    11821 tggaagatac ttttgactgg aatatagtga ttactttcaa aggagaaaat agatgaaaga
    11881 aacaaagatc aatcaagtca aaaaaaaatt atctcgttat caagaagttg tttatcgaaa
    11941 ccattgctta aaatggtcaa aaaataagct gaatgttcgt tttaatggat tattttatcg
    12001 tttcgaacag ttagaagaag tctggaaacc ggtaacgaat ttccaatcat gtcctgtaca
    12061 gctcataaat gatccaaaag aaacatacga tttatgtata acacaccttt ataaccagca
    12121 tttgaaaaat gacggatttt atttaaaggt tactaatgac aatcaactta cgattgaatc
    12181 agcaaacctt cgagggtttc aatatgctat ggaagcctta ttagagagtt ttttttcggt
    12241 aggagatcaa ttattattac cggaattgat tctgaaacat gaaccatcag tgaaaattcg
    12301 aggaatcatt gaagggtttt atggtatccc ctggacacat gaaatgcgcc tctctctttt
    12361 ttcatatatg aaagataacc aattgaatac ttttatgtat gcccctaaag atgatgaatt
    12421 attacgtaaa aaatggcgtg aactctacga tgcgcaagaa ttagacaaat ttaaggagct
    12481 tttatctgct gctgaggcta gcaatatcga tttttggtac ttaattagtc ctggaaatga
    12541 tattgatatt acgtgtgaag aagacattca agttcttctg aaaaagttag aacaactgat
    12601 tgagcttggc gtatttcaat ttggtctatt aatggatgat attgactatc aattaaaagg
    12661 tgctgctaaa cgccgttttc gagagccagc attcgctcat gcctatttag tgaatcgagt
    12721 agaggaatat cttagcactc ggttgtccaa tcatgaatta gtcatttgtc ctacagaata
    12781 tgataatcgt catggttctc gctatttagc aacgttaagt caagaaatac cagaacaatt
    12841 accgttcttt tggactggcc caagcacgtt agcggcgtca atttctacag aagagctgca
    12901 ggaaatggct tctgtctatc aacggccgat gctgatttgg gataatattc cggtaaatga
    12961 ttatttagag gataaagaac tattgttcat gagtccatat gagaatcgaa caccgaatct
    13021 ttctaaggag agataccagg ttacaggagt agtttcgaat ccaatggctc aattagaagc
    13081 ttcaaagttt acgatcaata gtatggctaa ttacttatgg aactgtgagc gttttgatcc
    13141 tttggaaact tggacgtcag tcgttgaaaa agtagttgga agtaaactac aaccagctta
    13201 tcttacctta accaatgctt ttccaaatca ttacacaagc agtctgcttt cagatgaaga
    13261 attactgcta gccaaagacc cagaatgggt cacaaaagaa atggctgctt tagtccaagc
    13321 agtaaaatgg atccagcaag aacaacatac atctagattg agaacagaat tggagccttg
    13381 gttacaagca atcacagaaa gttggacttt ctggcaagaa tggcaattaa aaaaagatcc
    13441 aaaagaagca gaagaatggt tggctaagaa aaaaacacac cgcataggac gtgatttagt
    13501 aactgcccat ttagagcaaa ttatcaaaag ttagatatct taaaaaataa aaagcaagaa
    13561 aaaggagaac aaaatggtca agagattaat tagtgcaaac tacagtgatg tcaagaaaat
    13621 gacgtcaaaa gagttgaagc aatccatcaa agcgagtgaa ggacgggtga ttgtttgtga
    13681 aacggttgct aatactcttc cacaatctgg agaaattacg aatgcagaag ttgcgtcagc
    13741 atttggtgca gatttgattc ttttaaatgg tttcgattgt tatcgtcctg cagtttttgg
    13801 actaccaaat gtgacgattg agaaggtttt tgatctacag caaacgattg aaaacccgat
    13861 tcctaaatta aaagaactag tcggtcgtcc tgtgggaatt aatttagaac ccattgcccc
    13921 taaaacaaat atgatgagtg agaaagtaga aatcagccaa ggaagagcaa gctctgttga
    13981 aacgatacaa aaagcagaag aactaggagt cgattttatt tgctttaccg gtaatccagg
    14041 cactggagta accaatttag aaattactaa atccgtaaaa atggcaaaaa agtatttttc
    14101 gggattgatt attgctggga aaatgcatag cgccggctca gaagagccag ttgtgaataa
    14161 agaggcgatt atttcttatg cggaagcagg cgcagatatt ttactagttc cttcagtagg
    14221 gtctatccca ggctttttag agcaagacct aattgaagcg gttcggttgg caaaaaaata
    14281 tgatttgtta acgatgtctg caatcggtac tagtcaggaa agtgcccgac cagaaacatt
    14341 gcggcaatta gccattatga ataaaagttg tggtgttgat ttacaacata ttggagatgc
    14401 tggatacggg ggattggcac cagcagaaaa tattttcgaa acctcggttg caattagagg
    14461 aatgcgacat accatcaact gcgttagccg ctcgatcaat cgctaacaaa attaaataaa
    14521 aaatggttaa attgattatt taagtgggaa catacttgag atatcagcta acttctgtca
    14581 ctttaaaaaa gggactgtga cagaagtgaa aatagacaaa aaatatccga acaagagact
    14641 aggatagcag aaaaactatc gttttgcaac gaggaccaac tggaccgtag gagcaattct
    14701 cttattgttc ggatatttcg cttgttcaag gacttatgtc tgtagtgccc ttttttggta
    14761 ggaaaaatgg tagggaacca tatcattttt aatgaaaatc aagcatttca aaagttgaaa
//
LOCUS       DAFLWC010000073        14528 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.074, whole genome shotgun sequence.
ACCESSION   DAFLWC010000073 DAFLWC010000000
VERSION     DAFLWC010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.074"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(101..247)
                     /locus_tag="L1V17_002160"
                     /pseudo
     CDS             complement(101..247)
                     /locus_tag="L1V17_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            486..1178
                     /locus_tag="L1V17_002161"
     CDS             486..1178
                     /locus_tag="L1V17_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBN1236910.1"
                     /translation="MNKKIVVSGLIIGGLVLAGIAGKNFADDILLWGGEDNIEQINHN
                     LESLDKALENKEQNISSLNSRLSSNNQELEQAKANVEEYKQKVLTLENDKNQLTIEKT
                     NLENQLSGKNAELQGKQNEINAKIDEINQKIAEINQLNTDWNNRLQTEQNKFNDAQNT
                     VNSLNQQINQLSNEKNTIKNQLQSTEQKLEKAQSENSNLNNYIEKLEKAKSDVEDTAN
                     RSQEIVTEHTGK"
     gene            complement(1460..1532)
                     /locus_tag="L1V17_002162"
     tRNA            complement(1460..1532)
                     /locus_tag="L1V17_002162"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1497..1499),aa:Lys,seq:ctt)
     gene            1913..2482
                     /locus_tag="L1V17_002163"
     CDS             1913..2482
                     /locus_tag="L1V17_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HBN1236911.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            2469..3329
                     /locus_tag="L1V17_002164"
     CDS             2469..3329
                     /locus_tag="L1V17_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBN1236912.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            3519..4223
                     /locus_tag="L1V17_002165"
     CDS             3519..4223
                     /locus_tag="L1V17_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1236913.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            4228..6063
                     /gene="walK"
                     /locus_tag="L1V17_002166"
     CDS             4228..6063
                     /gene="walK"
                     /locus_tag="L1V17_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HBN1236914.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            6060..7376
                     /locus_tag="L1V17_002167"
     CDS             6060..7376
                     /locus_tag="L1V17_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236915.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            7377..8246
                     /locus_tag="L1V17_002168"
     CDS             7377..8246
                     /locus_tag="L1V17_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HBN1236916.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            8301..9110
                     /locus_tag="L1V17_002169"
     CDS             8301..9110
                     /locus_tag="L1V17_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBN1236917.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(9213..9842)
                     /locus_tag="L1V17_002170"
     CDS             complement(9213..9842)
                     /locus_tag="L1V17_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HBN1236918.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            10012..11304
                     /locus_tag="L1V17_002171"
     CDS             10012..11304
                     /locus_tag="L1V17_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1236919.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(11380..12042)
                     /locus_tag="L1V17_002172"
     CDS             complement(11380..12042)
                     /locus_tag="L1V17_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBN1236920.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            12267..12551
                     /gene="groES"
                     /locus_tag="L1V17_002173"
     CDS             12267..12551
                     /gene="groES"
                     /locus_tag="L1V17_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBN1236921.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            12602..14227
                     /gene="groL"
                     /locus_tag="L1V17_002174"
     CDS             12602..14227
                     /gene="groL"
                     /locus_tag="L1V17_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBN1236922.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4914 a         2455 c         3071 g         4088 t
ORIGIN      
        1 ccattattat ctagtctagt ccattctttt tgtttgcagt atttgtgatg gctttccgta
       61 cccttagctc agttggtcag agcagacggc tcataaccgt ccggtcgtac ttctcgtaat
      121 ccaggaaggc cgtcagctcc gtccgcagta gcgtgtttac ggccagctcc agatgggagc
      181 ggaataactc gttcaaatca cctttggtgg ctagagtctg caggagttct gtaataaaat
      241 cgttcatagg gaagtcctct tttctgtgaa tgggtgtggt aactttattc tacagaaggg
      301 acttcctttt ttctatttac acaaaatatt ttatactctc aaatgtttgt atgcagttac
      361 atctgacttt attcgaatta aggaaaagat ttataaaaat aaaataaaaa aatatatatt
      421 taaattgact tattgtgaaa tcattaacta taattagttc agtttatgtt aaggagaatg
      481 atgatatgaa taagaaaatt gtagtaagtg gattaattat aggtggatta gtgttagcag
      541 ggatcgcagg gaaaaacttt gccgatgaca ttttgttatg gggtggagaa gataatattg
      601 aacaaatcaa tcataatttg gagtcattag ataaagcact agaaaataaa gagcaaaata
      661 ttagtagttt aaattcacga ttatcttcaa ataatcaaga acttgagcaa gcaaaggcta
      721 acgttgaaga atataaacaa aaagtgttga ctttggaaaa tgataaaaat caattaacta
      781 tagagaaaac aaatttagag aatcaattat caggaaaaaa tgctgaattg caaggtaaac
      841 aaaatgaaat caatgctaaa attgatgaaa taaatcaaaa aatagctgaa ataaatcaat
      901 taaacactga ttggaataat cgtttacaaa cagaacaaaa taaatttaat gatgctcaaa
      961 atactgttaa tagtttaaat caacaaatta atcaattgtc aaatgaaaaa aatactatta
     1021 aaaaccaatt gcaaagtact gaacaaaaac tagaaaaagc gcaatcagaa aacagtaatt
     1081 tgaataatta tattgaaaaa ctggaaaaag ccaaaagcga tgtagaagac acagcaaaca
     1141 gatcacaaga aatcgtgact gaacatacag gaaaatagat gcatttttta gtttaaattt
     1201 ctttaacaaa atagtatttt gttgctaaat aatttttatt tgaatattct acaatgatat
     1261 ctcccctcaa aatggagggg aagtacatac tgtgataatc tacaggttta ttgactgatt
     1321 aggatgttat taaaaaataa aatactaaaa tgcatacccg aatttcatac ccgaaaaata
     1381 aaaaatgcca ccacgtacac tcttttcgaa actacctaag tagccaagaa tgtactggtg
     1441 acgtgggttt ggcacccaat gggccgtgag gggctcgaac ccgcgacccg ctgattaaga
     1501 gtcagctgct ctaccaactg agctaacggc ccgtacaaaa agtacttaat aatagtagca
     1561 ctaagaattt taaaatgcaa gactacattt aaagaaaatc agaaaaatct ttacttcctt
     1621 ataggaaatc attcatagat tattcacatt tgctcgctat tatataagca taccaacaaa
     1681 caaagttctt gcaagagaac aaaccctaac acttttttca ttttttactc ctttcccgcc
     1741 gtctccccgg cgggtctcct gttcttaacg ataaaagaca agaaggctta gccttcttgt
     1801 tttttgtttt catggaatcc cgctaatcaa atcacctagt taaagcaact agattgaatg
     1861 tttatcataa gtctgatatc atgtttatga aatgaaaaaa ggagcggtta tgatggaaaa
     1921 aatgcgtcag caattaatgg agtgggggaa ggaactagaa acattccgtc tgcctcactg
     1981 ggaagaactc cctgacttag aactttatat ggaccaagtc agaacgttag ttgatcgtta
     2041 tctttcacct gtgatacaag gagaaaagca tccattgctt acctcttcta tggtaaacaa
     2101 ttacgttaaa ctaggtttga taccagcacc agttaaaaaa agatataaca aagaacacgt
     2161 agcattttta cttgcaatca ctacgttgaa acaagtattg actattcctg aaatcaaaga
     2221 agggatattg ttccaaggaa aaacagtagg aattcgtgaa gcctataatc tattttgcga
     2281 tgaacaagaa gcagctgtgt ggatggtcag ccaattagca caaggtaaat ctcatccgca
     2341 aaaattcgac caggcaaccc ctgtagaata tattgctgta agagcggcaa ctttatcgtt
     2401 tgcaatgaaa cttcttgcgg aaaaaacgat tgttctagaa accgaatatt taaaagagga
     2461 gaaaacaaat gaaaaacaat aaaatcgcaa ttttagtaga ttcaggtacg gatgtgccag
     2521 aagaattgat aaaaaaatac gagatgtata tgatcccatt gaaaattatt tataaagatc
     2581 aggtatatac agataaaatt gacattacct ctgaagagat ctatcaacgt ttgccagagg
     2641 aaatccctgg tacatctttg ccggatggtg agtcgatcac agaaatcttt gagcaaatca
     2701 aaaaagacgg ttatgaaaag gtacttgcgg taacaatttc cagtggattg agcgggacat
     2761 ataatgtggt tcgtttaatt gcacaacagc aagaagaatt ggaagcatat gtactagata
     2821 cgaaaaatat tggtattggt gcaggttttt ctgcgatcca agcagcaaaa tggctggaag
     2881 aaggagtaga atgggatcaa ctgatcagta atctgaatga gttagtcgaa agaacaaaag
     2941 ttttctttaa tgttgcgaca ttggaatatc ttcaaaaagg tggacggatc ggtttagttg
     3001 cttctattgt aggaaccgct ttaaagctta acccaatcat ctcatgtaat gaagaaggga
     3061 tttattacac agtaggaaaa gctaggggac gtaaaaaaag tttggataaa acggttgctt
     3121 acgtcaaaga aaaaatcggt aatgcaaagg tcttcaactt agctgttgcc catggggatg
     3181 cgaaagaaga agcaattgaa atggaagcga gacttaaaag agagttccca caagcaaacc
     3241 aaatctactt tggccagatt tctccggcat tagtagtcca cactggtccg ggattattgg
     3301 gtgtcggtgt acaagtttta gaaggataaa tcaaaaaaag gaaacactga ggtgaaaatc
     3361 agtgttttcc ttttttattg aagttagaac aaaaaataat aaagtatttt gcactttcat
     3421 tttaattttc tcttttgttt tataggcaaa gatgaaacaa aagcagaaat acggtataat
     3481 gagaaggtat gacaataata tataagaggt ggctctttat gaaaaaagtt ttagttgtcg
     3541 atgatgagaa gccgatttcg gatatcgtca aattcaattt agccaaagaa ggctatgatg
     3601 tttatactgc atatgatggg gaagaagcct tggaaaaagt tgctgaggta gaacctgatt
     3661 tgattttact tgatttgatg ctacctaaaa tggacggctt agaagttgct cgtgaggtac
     3721 gcaaaactta tgatatgccg atcattatgg taacagccaa agattctgaa attgataaag
     3781 tcctaggctt agagttaggc gccgatgatt acgtgaccaa gccattttcc aaccgagaat
     3841 tagttgcacg tgtcaaagca aatcttcgtc gcggtgccac ggctgcgaag gaaccagaag
     3901 aggcagcacc tgcggaattg acgattggtg atttgacgat ccatccagaa gcttacatgg
     3961 tgacgaaacg aggagaaaca atcgagttaa cacatcgtga attcgaacta ctcttttact
     4021 tggcgaagca ccttggacaa gtgatgacaa gagaacattt attacaaacg gtttggggtt
     4081 atgattattt tggagatgta cgaacagtgg atgtaactgt acgtcgtttg cgtgaaaaga
     4141 tcgaagataa tccaagccat ccaaattatt tagtgacacg tcgtggtgtc ggttactatt
     4201 tgcgtaaccc agaacaggag taattggatg aaaagaaaag tccgcttttt tcgatcagtc
     4261 aattttaaga tcgctattac ctttattctg attttattga tctcgatcga aattattggt
     4321 gcctacttta tacgtggttt agaacgttcc acgatcaata catttattaa agatatgaat
     4381 caaacggtgg aatcattagc aacaacaatc agcccggaat tgaatcgaaa agataatgca
     4441 gatgatgaag aggtaaatgc gaatatcaaa agatttattg aaaacagtgc gactagcgat
     4501 atcatcgaaa tacgggtcgt tgacgaaaaa gggatcatcc gaggaacaac cgatgtcaat
     4561 gaacaaagcg ctgtgggaaa gaaaaatgat tatgttgata tcaatgattt cacgactaaa
     4621 cgttatgttg ctttagataa cgacgataaa cgggtgaata tcaatgttca accgatcctg
     4681 tccccgaccg gcgatgccgt tatcggggct ctttacgtca aaagtaatat cgaacaaaaa
     4741 tattcggaaa tcaataacac agcagtcatt ttctttactg cctcactaat tgcggcattt
     4801 atttcaatga tcgtatctgt tttagttgct cgttcgatta cacagccgat cggtgaaatg
     4861 agagaacaag ccattcgaat cgctagagga gactacagtc ggaaagtcaa agtgcatgga
     4921 caagatgaac ttggacagct ggctgatacc ttcaatcagt tagctgaacg tattgaagaa
     4981 gctcaagata caatggaagc tgaacgcaat cgtttggata gcgtgctatc ccatatgaca
     5041 gacggcgtca ttgcgacaga tcgcaggggt aaagtcatta cgatcaatga tatggctgtt
     5101 tccttgctag atatcaaaaa cgaggaagca atcggacaat cgattttgac acttttagat
     5161 atcgaagaag aatatacgtt gcggaaatta ttagaagatc caaacgaaat ggtacttgac
     5221 cgttcaacca gtacattgga aagtgatcag atgatcttgc gagtagactt ttctatgatc
     5281 cgtcgcgaat caggttttat cagcggatta gtagctgtct tgcatgatgt gacagaacaa
     5341 gaaaaaacag aacgggaacg tcgtgaattc gtctctaatg tttcccatga acttcgtaca
     5401 ccgttgacaa gtatgcgtag ttatatcgaa gcattgagcg aaggtgcgtg gaaagacgag
     5461 gaagtagcac caaatttttt gaaggtaacg ctagatgaaa cagaccgaat gattcgaatg
     5521 atcaatgacc tcttaaatct atctcgcatg gatacaggta atacccagct tcaattagaa
     5581 tatgtcaatt tcaacgagtt agtgaatttt gttcttgacc ggtttgatat gatggtggga
     5641 aatcaggaaa aaaattataa gatccgtcgt gaatttacgc aaagagatct ttgggtcgaa
     5701 gtagatacag ataaaatcat ccaagtagtc gataatatca tgaataacgc gatcaagtat
     5761 tcaccagatg ggggaacgat tacttgtcgc ttattagaaa cgcataataa cgtggtttta
     5821 agtatcaccg atcaaggatt ggggattcct aaaaaagatc tgaaccgagt gttcgagcgg
     5881 ttctatcgag tagataaagc acgtgcaaga gcacaaggtg ggacaggact tggattagct
     5941 atttctagag aagtgattaa ggcgcatcga ggcgctattt gggcagagag caaggaagga
     6001 aaagggtcga ctttttatat ctcgctgcca tatgaacctt atgaggagga atggtgggaa
     6061 tgagaatctc tgaaaaagtc gttcgtatag gactcatttt gatggttgcg ttaagcatat
     6121 acttctctta tgcaatctgg ctgagcccag caggaaaaag ttcaatcaac gtagatgaga
     6181 caaacactca aatgatcgag tctcaaagca atcgaaaaac ttccgaagtc tttcttccgc
     6241 ttcatgttac atggcaccat tcgggaatga tccaagaaac caacagtgaa aatctcgtgt
     6301 accgattgca attgatcatc gataaagcaa gatttggaaa gctttctgaa gtagtttcag
     6361 gagacaaatc acagtttgaa caggtgaaaa atctgaactc tggttttgag ttggcctata
     6421 atgcgccttt tttgctaaga gaatacaagg aagcatttga tttagattta gatgtgtcga
     6481 acttggcaaa agaaagcgaa aatatgtatt ttactagaat acaattcgat caaggaaata
     6541 aaaaaatccg atttttgaat tattcgaacc atctcgtata tgaagcaaat atttcgttga
     6601 attggacaga tatcaataaa gaattaacag caaaagacac aaaatggaca gaaatgacaa
     6661 cagaaccatc gacgatcgac acgcaatatg ctacgaaaca ttcgatcaaa ctgaaaaagt
     6721 atagttatat cctgtcacag caaccctata cactttttag aaatgctttt ttccagaaac
     6781 cagatagcgt gaaaaataat gatgaaagca atgaattgat tttttacggt gggaatgaaa
     6841 caatgtctat ccattcggaa acgcaagtag ttgattttcg tggagagctg ccagagaaaa
     6901 aagaaaatgc tagtgtattt tctgaaagtt tcccctatat tagcaaatta ggcagttctt
     6961 tagggaacct cagatatttt gaccgcagtg acaatacgat cgattatcgg atattcgtgg
     7021 aaggcttccc ggtttttggg acagacagca gaggacagat tggtgtggaa gttggcggtg
     7081 aaacgaatgg ttctgtgcaa gtgaatatcc aaaccagttt gaatacgatt caagtgccga
     7141 taccttcaga cgaagaagta gaacttgcaa gtacgaatga aatcatccag cagttaaaag
     7201 ctaagggagc agatagcaac aagattggtt cagtgatcgt tggctataca tggcaaaatg
     7261 tcaaagaaac gaatcgtgtc gttgatctct tacctgaatg gtatgtgaaa tataaagata
     7321 actggtattc agctaacgac cttctggaaa aattacctgg attggaggcg aattaattgg
     7381 atttcaaaaa aatcgaatgg atatttttcg tcgctttttt agggttgaat gtgtttttat
     7441 tcagcagtta tcatgacgcg gtataccaag aaaacaatgt cattcgctct aatcagactg
     7501 aatcaatcca acaacgtctg gctagcgacg atatcactta cacggggaag atttcgtctg
     7561 agaacaagca aggctattat cttagcgcgg agcagaccaa tcttagcact tcattagcga
     7621 attatcgcaa ggctggtaaa agcggcttgc tggcaagtgg tgtgttttta gacggtgatg
     7681 ttttgacgaa atctttatcc agttcagatg ctgaaaagaa cgtgatcgat ccagataaaa
     7741 ttagtagttc cttggaagat tttttatcta acaaagacaa tattttattc ggtaatgatt
     7801 atgtgtacac gaaaaacttt tctcatttag aagaagaacc actagaaatc caagcaagcc
     7861 aagagtatga aggcatccca ttcaatgatg atacagcaaa aatcgttctt tctttagaaa
     7921 aaaacgataa tgattatagc atcacgaaat acatgcagac gcatttatct gatatcgagc
     7981 agctgcgcga aaagacggaa ctgtatacgg aagaggaagc aatcaataca ttgtacatca
     8041 ataacaaaat accaagagga tcaaaaattt tatggcgtca gctagcttat tcctgtattc
     8101 tgaaagtccg ggaaaaaaat gtgtatgttc ctgtttggca tgtagcgatc gaaacaagcg
     8161 ataaagtggt ccaaattgag agtgtcaacg ctttcagcaa tacgatcgtg acaaacaata
     8221 ctgtaccaaa agtggaagat caataaaaaa gcgagtataa tgaaaaaagt ttacaaagta
     8281 agaagggaag taggagtcaa atggctgaag aaaaaccagc ttttaaaatc agtatcctag
     8341 caagtggaag ttcgggtaat tcactttata tcgaaagtga aaaaaaacgg cttttggtcg
     8401 atgcaggact tagcggtaaa aaaatcactt ccttgatggc tcaaattgat cggacaccgg
     8461 accaattaga tggaatactt gtgacgcatg aacatcgaga tcatatacat ggcgtgggtg
     8521 tcttggctcg taagtatcat ttggatgttt ttgccaatca gcagacttgg gaagcgatgg
     8581 aaccactgat tggaaatgta ccagtggaac aaaaacatct atttgagatg gggaaagtca
     8641 gaacattcgg cgatatcgat attgagagtt tcggcgtctc ccatgacgca gcggctccgc
     8701 aattttatcg tttccataaa gaaaatcggt cattcgtcat gttgacggac accggatatt
     8761 gcagtgatta tatgcgaggt gtcattgaaa atgccgatgg ttatttgatg gaaagtaatc
     8821 atgatcttga gatgttacgc atgggacctt atccgtggaa tttaaaacag cgtattttag
     8881 gagatagagg acatctttcc aacgaagacg gtgcacttgt catgactgat gtgatcggta
     8941 atcggaccaa acgaatctat cttggccatc ttagcaagga aaacaatatg aaagaacttg
     9001 ctcatttaac aatggaaaat gttttgaaag aaaaagattt tggcgttgga catgattttg
     9061 aaatctatga tacagatcca gatgaagcaa ctgagctatt ttcgatttaa acagttcaat
     9121 caataaaaat ataaaaagca gaagataaaa tcaatcaggg ttggttttat cttctatttt
     9181 tattttttta gcatattaaa aaaataaccg tattatcgac tgactacact gatgtgctgc
     9241 ttttcatgtt tctcatccag tatctcatct actaatgcaa tcgcgtaatc tgccatgctg
     9301 atcgtactgt cgccagcagc gtttctttgt aaataatcat cacttaacaa ataagtacct
     9361 gtacgtttgc catgtggatc aaataaagaa gctggactga tataagtcca atgtagattt
     9421 ttagattgtt tcaattttaa caatccttcg tacatattga aagctgttgg atagaagggt
     9481 gcatttttag gtacttggtc aatcatacga gtcgtctttt ctgtatctaa gaataacgaa
     9541 gaggcacccc caacgacaat taagcgtgta tcggttcctt caagcatctc aatcaaatgg
     9601 gacaaagaag tttgatgcat ttcttctttt cctttgggag cgttgaaagc atcaacgaca
     9661 acatcaaaag atgcaagatc agtagttgtc aactcaaata aatccttttg tataaacgga
     9721 acatctgatg gcaatttttc tggatgacgc acgattgccg tcacgtctaa atctctggac
     9781 aatgcttcgt ctaaaataaa tgaacctgca tggccagtag ctccaatgag tgcaattttc
     9841 ataaaaaacc tcctttttta ttcctgtcca ttgtaagcag ttgctgaata ttcgtcaaag
     9901 aatccgattt ttgaaaagct cagtgcgcat tcctttcatg gttcgtgatc attgggtata
     9961 gttaaattaa gaaaactgat tgataaaaat agaagttgaa ggagataaga aatgaaagag
    10021 tggttagatc gtgccttttt accaatgata acatctgttg tgaatcttag acccttaact
    10081 gctttgcgta atggaatgac ttacacgatc ccaataatta ttgttggctc gctgtttttc
    10141 ttatttgctc attttcctgt ggattacatc gctcagtgga tagacaaaac aggattttct
    10201 atgtatttta cacaagtata ccaggctaca tttgatgtga tagccttttg gatcgttttt
    10261 gccattgcat acgcttatgc aaaagaagaa gacatcgatc gcttaccagt cggcataaca
    10321 gccttgtctg cttatctact gcttattcag ccactaaata ctcagataga tactgtctgg
    10381 acaggtgctg aagggatact aggagcagtt acaactgggc tcatcatcgg atggggctat
    10441 gcacgtttag taagacttgc gaaagggtgg aagcaaagag agaagatacc tgaaaatgtt
    10501 tggcagtctt ttacttcatt gattccaatc attgttatag tcacttttac gcttatcggt
    10561 tcagcggttt ttcaacagtt gttcagaatg actgttgttc aaggagtatg gacatatgtc
    10621 cagcttccca ttcaatcgtt catagacacg ttgtttggtg tgcttttatt aggttttttt
    10681 gttccgtttt tatggttatt tggtcttcat ggatctgcga tggtcaatgg gttggttagt
    10741 cccgtcttgc aagcgaattc attagcgaat gcagaaatct tagcctcagg acaagagttg
    10801 acggtggcaa atggcggaca tatcgttact cagcaatttc tcgatcagtt catgacggtt
    10861 acgggtgctg gattgacgtt aggggctgta ttttttatga cggtttttgc gaaatcgaag
    10921 aaatacagag aattaggaaa tcttgctctt ttaccagcct ttttcaacat caatgaatca
    10981 attatttttt ccacaccgat cgtgatgaac ccgatgatgg ctgttccttt tattttcgca
    11041 ccggtcgttt caggattgat tacctattcc gctttatatt ttggattcgt tcctttattt
    11101 acagcagtcc aagtcccttg gacaacaccg ccgatcctct cgggtttctt agtaggcgga
    11161 gtgcctgcag cgattttaca aggtatcgtg ttgtcaatta gttttttcat ttatttccca
    11221 tttttgaaaa aaatagattc tgcaaactgc aaaaaggaaa gacagacaaa aaatgatgga
    11281 gcagcagaaa agatgaacga ctaaaaaaca aaaatactcc tgtcgcttta gattgggaaa
    11341 atcaccaatc taggatgaca ggagtattta tagtcatgtt tatactagcc ctttttggac
    11401 agctaattga acaagaacaa ctaatgtgtt cattcctacg tgtgtgatca tcgatgtcca
    11461 gatccgacca gttgctttgt actctaggct gaagaagaaa cctaggaaaa agtagattag
    11521 cagatgacca tcattatgag caaacgcaaa cagcaaagag ctgatcactg ctccgaccca
    11581 aaaatttgaa tatcgactga tgatccccag tatactgcgg cggaatacga actcttccat
    11641 gatgggtcca gcaacagttg tcgccaaaat aaaagcgggt gcttccatga tcatctggat
    11701 gatattttgt gtattctcgg aaggggttgc tttgccaaac aatacagatt ctaacatgac
    11761 agcgatgctt tgcagaatca atgcgacaaa gattccaacc aatccataaa taacaatctt
    11821 tggagcagaa gcttttttta ccgctgattc gatcgctaag ggttcacgtt gcttaaaata
    11881 aaaaatagct aggacaacgg cgcctagtat atacatgact gcagttgctg tgatcaattc
    11941 agacgtagat tttacaagtc ctatcgaagc taggatcaag ggtgagataa aaattagacc
    12001 atagcaaaaa atgctgagga agctatattt ttttaaagac atgtaattcc tccttttaag
    12061 ggataacaag catgcaaggc aagcttatat cgattgattt caattatatc ataatttcaa
    12121 taagcagctg tcagaataaa atttcttttc tttgatttaa aagcttgcaa aaaagaggga
    12181 gaatgagtat tattaaaaat gtaggttagc actcgaaggt taagagtgct aacagattaa
    12241 aaaaagagtt atcggaggga tttatcgtgt taaaaccatt aggtgatcgc gtcattatcg
    12301 aagtcgcaaa agaagaagaa aaaactgtcg gaggaatcgt tttagcttct gctgctaaag
    12361 agaaacccca aactgggaca gttgttgcag tcggtgaagg ccgtttgtta gaaaacggtg
    12421 aaaaagttcc tgccgctgta aaagcaggcg accaagttat gttcgaaaaa tacgccggta
    12481 cagaagtaaa atacgaagga aaagaatatc tgatcgtcgc aggaaaagat atcatggcga
    12541 ttgttgagta aatttggaag ataaaaaaat aatcaaaaat aatcaatgag gtgaatcaat
    12601 catggcaaaa gaattgaaat ttgcagaaga cgcacgcgca gctatgttac gcggggtaga
    12661 taaattagca gatacagtga aagtaacatt aggacctaaa ggccgaaatg tcgtactaga
    12721 aaaatcttac ggctctccat tgatcacaaa tgatggtgtg acgatcgcaa aagaaatcga
    12781 attagaagat cattttgaaa acatgggtgc aaaacttgta tcagaagtag catcaaaaac
    12841 aaatgatatt gcaggagacg gtacaacgac agcaactgtt ctgacacaag caatcgttcg
    12901 cgaaggttta aaaaacgtaa ctgcaggtgc taatcctcta ggcattcgtc gcgggatcga
    12961 attggcaaca aaagcagcag tcgaagaatt gcataatatc tcaactgttg ttgattcaaa
    13021 agaagccatt gcacaagtag cagctgtttc ttcgggttct gataaagttg gacatttgat
    13081 tgctgatgca atggaaaaag ttggaaacga cggtgtcatc acaatcgaag aatcaaaagg
    13141 gatcgaaaca gaactagatg ttgtagaagg tatgcagttt gatcgtggtt acttatcaca
    13201 atatatggta acagataacg acaaaatgga agctgttcta gaaaacccat atatcttgat
    13261 cacagacaaa aaaatctcta acatccaaga tattctgcca ttgttagaac aaatcttgca
    13321 acaatcacgt ccattgttga ttattgctga cgatgtagat ggtgaagcat tgccaactct
    13381 tgtattgaac aaaatccgtg gaacattcaa cgtagtagct gtaaaagctc ctggtttcgg
    13441 cgatcgtcgt aaagcaatgc ttgaagatat cgctattttg acaggtggta cagtaattac
    13501 tgacgatcta ggtttagaat tgaaagatgt aacaatcgaa aacttaggaa atgcttctaa
    13561 agttgttgta gataaagaca atacaacgat cgtagaaggt tctggagaaa aagaagcaat
    13621 cgaagctcgt gtgcaattga tcaaaaacca aattgctgaa acaacttctg attttgaccg
    13681 cgaaaaatta caagaacgct tagctaaatt agcaggtggt gtagctgttg ttaaagttgg
    13741 tgcagctact gaaacagaat tgaaagaatt aaaattacgc attgaagatg cattgaatgc
    13801 tacacgtgcc gcagtagaag aaggaatggt ctcaggtggt ggtacagctc tagtgaacgt
    13861 tatcagcaaa gtttctgctg tagaagcaga aggagacgtg gcaacaggta tcaagatcgt
    13921 tgttcgtgct ttagaagaac caattcgtca aatcgctgaa aacgctggtt atgaaggatc
    13981 agtgattgtt gataaattga agaacgtgga actaggcact ggtttcaatg ctgctactgg
    14041 agaatgggta aacatggttg aagcaggtat cgtagaccca actaaagtaa cacgttctgc
    14101 cttgcaaaat gccgcttccg tttctgcctt gttattaacg acagaagcag tcgttgcaga
    14161 taaaccagaa ccagcagcgc cagcagctcc tgcaatggat ccatcaatga tgggcggtat
    14221 gatgtaagaa aaagcaactt gcttatctac aactgatcat tagtgaaaga cagataaaaa
    14281 gaggctggaa cagaagcgtt taactccaag aaataagaag aaattcacgg aaattgcttt
    14341 tcaaattttt gtgaatttca gcttatttcc gaaggagttg cttctgcttc cgctgtttat
    14401 acgtgtttag agcgtgagac aaaagtgttc tttacttttg tcccacgctc ttttttgtgt
    14461 gtaattataa tgaaaatagt tatttttaat agttataata ttttatctat taaaagtaaa
    14521 tatccatt
//
LOCUS       DAFLWC010000074        14381 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.075, whole genome shotgun sequence.
ACCESSION   DAFLWC010000074 DAFLWC010000000
VERSION     DAFLWC010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14381
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.075"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(27..923)
                     /locus_tag="L1V17_002175"
     CDS             complement(27..923)
                     /locus_tag="L1V17_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBN1236923.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(916..1596)
                     /locus_tag="L1V17_002176"
     CDS             complement(916..1596)
                     /locus_tag="L1V17_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1236924.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(1597..2379)
                     /locus_tag="L1V17_002177"
     CDS             complement(1597..2379)
                     /locus_tag="L1V17_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1236925.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(2372..3289)
                     /locus_tag="L1V17_002178"
     CDS             complement(2372..3289)
                     /locus_tag="L1V17_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1236926.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(3453..3776)
                     /locus_tag="L1V17_002179"
     CDS             complement(3453..3776)
                     /locus_tag="L1V17_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236927.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWKTTQPRLRDSLIFLGGSLAIVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEK
                     KESGN"
     gene            4564..7791
                     /gene="fss3"
                     /locus_tag="L1V17_002180"
     CDS             4564..7791
                     /gene="fss3"
                     /locus_tag="L1V17_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBN1236928.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            7904..8218
                     /locus_tag="L1V17_002181"
     CDS             7904..8218
                     /locus_tag="L1V17_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBN1236929.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            8231..8605
                     /locus_tag="L1V17_002182"
     CDS             8231..8605
                     /locus_tag="L1V17_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBN1236930.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            8615..8950
                     /locus_tag="L1V17_002183"
     CDS             8615..8950
                     /locus_tag="L1V17_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HBN1236931.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            9033..10373
                     /locus_tag="L1V17_002184"
     CDS             9033..10373
                     /locus_tag="L1V17_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBN1236932.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            10451..11125
                     /locus_tag="L1V17_002185"
     CDS             10451..11125
                     /locus_tag="L1V17_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBN1236933.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            11118..11282
                     /locus_tag="L1V17_002186"
     CDS             11118..11282
                     /locus_tag="L1V17_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236934.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            11358..12500
                     /gene="dcm"
                     /locus_tag="L1V17_002187"
                     /pseudo
     CDS             11358..12500
                     /gene="dcm"
                     /locus_tag="L1V17_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            12490..12780
                     /locus_tag="L1V17_002188"
     CDS             12490..12780
                     /locus_tag="L1V17_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236935.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            13039..14223
                     /locus_tag="L1V17_002189"
     CDS             13039..14223
                     /locus_tag="L1V17_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBN1236936.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            14220..14357
                     /locus_tag="L1V17_002190"
     CDS             14220..14357
                     /locus_tag="L1V17_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBN1236937.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
BASE COUNT         4596 a         2632 c         3019 g         4134 t
ORIGIN      
        1 tactagttct cactaatctt gtataattaa accctccgca acttgacgga gatggagaag
       61 atgcccccgt ctaatctagc ggtcatctct cctcccattc cttccaccaa tttttttgac
      121 aggtaaagcc cgattccgct agattccgta tttgtgcggc tggtattttc ggtataaaaa
      181 cgctggaaga ctttttcaac agaggtttgc gttcctggtt tgataggatt ggccactgtt
      241 aatcgaatga atggatcctc ttttgaaaat gtcacctttg cttgtccatc tgcataacgc
      301 aataaattct gtatgatatt ttgcagcact cgcagcaaca tgagcggatc tgctaataca
      361 gttgtattta tcgagtgttc agcgaacgct acctcgatat ttttctcaga aaattgttca
      421 taaaaagaga aaaatacttc ttccacctct ttagaaaaag aaagcgtatg gagatccatt
      481 tctttttgct tcgtctctat tcgagcaaga tcataaaact gatccgtcat actgagtaat
      541 cttgcaacag attgtttgat gatcgttaaa tacttctccc gtttctccgt atcctctacc
      601 tgttccagta attgtacata accgttaata gcagtcaaag gagttctgag atcatgagaa
      661 aggccgacga tcgatagtct gatgttttct tccatttctt gaaatgcttg tcctttttgt
      721 tcattttcat ccaaccatgt attcagtgca tctactaggt ccattagatt cttttctcga
      781 aattcgactg aaagacgacc accatattct tgtcgttcag aaagagtggc gattttctta
      841 gttaatctct tgatttccct ttgcaggaag aaaataaaac ttcccataaa gataacaacg
      901 agaagcaaca gccatttaat caaatctaaa ccccactccc cacaccgtat gaatatacac
      961 agcatgtgcc tttgctagct tccctcgaag attggaaata tgcatattca ctgttttctc
     1021 actatcaaaa tatggttctt gccaaactgt ttcataaaga tttgctcgcg aaaatacttt
     1081 tttcggatgt tctaaaaaaa gcttcagcag atcgaattct cttcctgtca aatggacagc
     1141 cacaccattc acatttacat ccctcgactc tttgtccagt aagatttcct tgtaatagat
     1201 gcgttgcgac agatctttta cttggacaga agtctgatga cgaagttgga tgccgattcg
     1261 taacaaaagt tcttcgatat caaatggttt cgtcacatag tcatccgctc ctgctgccaa
     1321 caaggaaact ttatctcttt gatcgctttt tgctgaaaga acgatgatcg gaacattcga
     1381 tgtctgtcgg atttctgcta acaatgcttc acctgaaagc cctggaagca tgagatctag
     1441 aaggatcaaa tcgacaggat atgtgcttaa caataatttt ccttccgtac ctgaataagc
     1501 atcaagaagt ttgtatctct gttcaagaac ctcctccagt aaggaatgaa cagcttcatc
     1561 gtcttcgata atcaaaatag tttccagcag gaccacctac ttaatgtcag atttttggaa
     1621 aataaacatt cctagagctg atgataccac gattgttact agactgacca gaatcatttt
     1681 cggtgcttgc gaataagttg cttgttgcgc aaagtccgta tacatgagcc acgtttccgt
     1741 aaaccactcc gttagaaatt ccaagccttt gatttttgcg aaaacaccgg gaatgaaggc
     1801 cgttcccatg atataaagaa aagaaagaag caaactgaca ctggtacttc tagtgatgaa
     1861 tgtcaaagcc actggaacag ataatgtccc taatgtcagc agaagcaata caggaaatac
     1921 ttttagaaca taatttccat agtttttgat tccctcaact tcaccaaatc cgaaagcaag
     1981 tgtgtaagca agcatggcta gtcccgtgat caaaaccacg ccaagtgttg tgatcaaaag
     2041 cgtaacgaga agtttcgaca cataataagt cattcgattc cgtcctaaag ataacgtatt
     2101 gcgaatcgta ccgttttgaa attcttcccc aatataaaag cacgcaaatg ctgcgaaagc
     2161 cagaagaatc catgcagcca ttttttctac cattaaaatc cctgttgcac cgttgatgac
     2221 tgtatccgtt gcttggttta attcattgcc gtattttgta tgcatatacc attcgttcca
     2281 agaataaaaa agcggaagta cgaccatcag tcctagtgag acccacattt tacggctctt
     2341 ccatactttt attttttcag cagttaatag attaaacatg tggattgcct ccagttaatt
     2401 gtaagaaata atcttccagt ttttgcccaa ctaggtgaat accatccaca ggaacttttg
     2461 cttctaccaa tgcttgattg atggctgcta cttggtcaat tccttcaaaa agctggataa
     2521 cacggctaga ttgtacaaaa taatccctat aaccaagaga gtcgagaacc gttactgctt
     2581 gttccgtcgc cgaagtgtca atttttataa attgacgaga ttcttgtgcc aattcttctt
     2641 tcgataattc tttgatcaag tgtccttcat gcaaaatacc atagtgagtg gcgatctgtg
     2701 acaattcatc tagcaagtgg ctagaaagca agacggtgat gccccgttct tttaccaaac
     2761 gttggatgat ttctcgcatt tctgccatcc ctgctggatc catcccattc gtcggttcat
     2821 ccaaaatcaa aaattctgga ttcgtgatca gtgcatttgc aatagctaaa cgctggcgca
     2881 tacctaaaga gaaattcttt gctttctttt tccctgtatt ttccaatcgc atcattttca
     2941 gcaggtcttc gatttctcta tccgacacac cgccgttcgc tgcttggata cgtaggttat
     3001 ctcttgcagt taattctgga taaagagcag gggtttcaat cgattgaccc atacgtcgtc
     3061 ttgctgcctg caaatccgtc gttccaaata attcgatcga accttcatca atcgagatca
     3121 aacccataat agttctcata aaggtagact tacccgctcc attttcccca atcaatccat
     3181 agatcattcc acgtttgatt tcgattgata ctttatctaa tgctttggca gcaccgtatt
     3241 ttttggttat accagttgct ttcaagaccg tttcatttcc aaaatccata cttatccttc
     3301 tttcttattg atgagtgaag tatagttgac gggtataaag aaagcagcca gaaatgtata
     3361 aagaaagtgt aaattttcca attgaatgtc aaaaaaaaca atcggacaat acgtgtcttt
     3421 cctattatca ggcagtttgt tatacgcttg tatcagtttc ctgattcttt cttttcgacc
     3481 aaagtcgttt ctctgtattc ctcttcactg aaaatttttg cttctttcag atcaagcttg
     3541 agtaatttta ccagaccggt tataaggata actatagcaa gactccctcc cagaaaaatt
     3601 agactgtctc gcagacgtgg ttgcgttgtc ttccaatcaa agagcgcacc aaacagtgct
     3661 aatccaagtg gactggccac catggtaatc gttgttatcg ttgacataag tcgtccttgt
     3721 atatgcgttg gaacttctcg ctgaagccag accatataaa aagcaaaaga aaacattaat
     3781 ccttaaaaac ggacttatga aaaataatac atgccgtttg ggatttacaa ttagctacca
     3841 aataagaggt tatgacaaaa gacttttcac aatcccttct tccgaataaa cggtgttctc
     3901 ctgccaactc ctcggtcaca agtcacaata tttatcaaac atgagaagca atttttgtaa
     3961 attccttctt atttcttgaa gctgaccact tctgtcacaa cctcagaagc ggataaataa
     4021 tattgtttga tgatacttta tctttttccc gtttgtttat agatcgaatg atattataga
     4081 ccaagaatcc tacctattaa catagctaaa aacacaaaaa aggcactttc caaattgtgg
     4141 aaagtgccag aaaagttagg attaaggtaa ctgcgctcag cattgcttcg cccagtacga
     4201 ttctcgtaac tcgtgaactc gaacgataat cgcaattaac gttttgagaa ctgtgaagct
     4261 ttacgggctt tcttaagacc tggttttttc ttcgtatcat tgaataagtt tgaaaaacct
     4321 tgatttataa aggttttccc gtaaatatat tttattatat ttgattaaat ttgaaatgtt
     4381 tgtgttctaa aatgtgttct aatttaaagg cagtatattt cgtattttag attaaatttt
     4441 taggctcatt cattctcaaa tccattctat tcagtcaata aaaattttaa aaagacttta
     4501 taaacaaaga tgttcaagcg agcatcttat ttttttgtgc ttaatttgaa aggagaacat
     4561 ttcatgtata aaaaacaaaa aaagaaatta tgtgtattaa ctattttgag tttggctgtt
     4621 caagcaattg ttggagcaat tgctcctacg attacttttg ctgatgaaat tacccatcca
     4681 caaacggtaa ccgtagaact agatttagca catcaatatg ctgttgaagg aacttttagt
     4741 gatggtcgtc caatgtcaga agtcactgtt ccgcattatg cagtgtacaa cggctttaaa
     4801 caagatattt tctgtattga accaggagtc ccgatttaca atgagttcac tcctggctat
     4861 gagaaaaacc cgttaccaga tatgtccgat aaagccaaat tagtttccgt tttatggaaa
     4921 aaagtaggta cagatgcaga tactcatatt gtggcacaga agatgatctg gcaagaagtt
     4981 aatgggtata cccttcactc aataaaacga tcagatggta gtgccgtaaa tatcgcagcc
     5041 attgaggcaa aaataaatca agccattgac gattatcaga agaaaccaac cttccataat
     5101 agtacggcta aaacagtatt agggcaatcg actactgtga cggatacgaa taatctgaat
     5161 ttgtcagagt tcgatgaggt tgtggaaaat gccgcaaaca ttgattatcg tgtgaatggt
     5221 aatcagttga taatcacccc aaatgccaat tcaaaagaaa gtggtgtgct gacgcttaag
     5281 aaatctgctg gtaccggaac acctgtcgcc tataaaaagg ctggccaaca gactttaatg
     5341 gccggggcga ttgataaacc taatacctac acaatcaaaa ttgatgtgga aacggagggt
     5401 tctttaaaga tcaaaaaagt cgataaagaa tcgggtgatg ttgtaccagg aacggttttc
     5461 catttagact ttggaaaaac tttacctgca aaagacgtga ctactgacaa agaaggcatt
     5521 gctacattgg atgagattcc tcatggtaca aaagtaacca ttaccgaaaa atcagtaccg
     5581 gcgccttata cgattgatac cacccccatg actaccacca ttaaagcagg cgaaaccatt
     5641 tacgtgactt caaaaaacgc acgggaaaaa gggcaaatca ttctggataa aagcggagtt
     5701 gaaacaggga gtgatctttg gaatgacaat tattccttag ctggtaatac gtttgccatt
     5761 cgcaaagaca gtccaaccgg tgaaatcgtt caagaaatga ccacggatga aaacggtcat
     5821 gcggaaacac caaaagagat tgctaatgcg ttggaattgg gaacctatta tgtgaccgaa
     5881 actaaagcta gtcatgggtt cgtgaatacg ttcaaacctg taaaagtcga attgaagtat
     5941 gccaatcaaa ccgtagcccc tgttaccagt aacgtaaaag ggcaaaatca agaagtcact
     6001 ggcgaaacca ctttgacgaa agaagacaaa gatactgggg ataaagcaca aggtaaggca
     6061 gtctttgagg gtgctgaata caccttgttt actgctaagg atggaaaagc tgttaaatgg
     6121 agtgaggctt ttaaaccaga gttagcgaag ggaacgaaag gttctgatga aacggtcact
     6181 ttgactttag acgaaaagaa ccaagttgcc gttaaacatt tagctatcaa cgagtattat
     6241 tggcaagaaa caaaagcgcc cgaaggatat agccttgatg aaacaaagta tcctgtatcc
     6301 atcaaaaagg tggatgatag cgaaaaaaat gccgtgatta cccgaaatgt tacggcaaaa
     6361 gaacaagtga ttcgctttgg ctttgatttc tttaaatttg ctggatcagc tgcgggcact
     6421 accgaaactg gcttcaatga tctgaccttt aaagtgtcgc cattggaagg gaccaatgaa
     6481 atcacaggtg ccgaagatga agcgaccaca gcttataacg agcaattagg gtttgatggt
     6541 tatggcaagt ttgaaaatct tccttatggg gattatttac ttgaagaagt agaagcccca
     6601 gaaggttttc aaaagattac gccattagaa atccgttcta cttttaagga aaacaaagaa
     6661 gactttgtga agagtgagta tgtctttacc attaccgaac aagaccaaaa acaaccaatt
     6721 aaaacggtga ccgttcctta cgagaagctg acgaacaaag cattttctgt tagtttgaac
     6781 cgtttaatgc tctatgattt gcctgaggaa gaagatagtt taacttctct tgcgacttgg
     6841 aaagacggaa acaaagaatt aacttctctg gattctaccg agctagttga taaattgagt
     6901 tacaatctac atgaaatcaa agaagactgg tatgtggtag cgcaagccat tgatgtggat
     6961 gcgacaaaag ctgcccaaga aaaagatgaa aaagccaaac cagtggtgat tgcagaaaca
     7021 agcgcaacgt tggcgaacaa agagaaaaca ggaacttgga aaattcagca taaattaacc
     7081 gccgaacaag ttttaaataa aactattgtc ttattcaact atgtgtatga aaataaggaa
     7141 gcttttgaag caggcgataa gccagtagcg aaggatgtta gcttgaataa ccaagcccaa
     7201 actgtcagtt gtacagtgga acaccatgtt tctatccaaa caaaggccca cctagaaaac
     7261 ggttctcaga cctttactca tggtgatgtg gtggatatgt ttgatgatgt gtcgattact
     7321 catgatgtac tggatggctc aaaagaagct ttcgaaacaa ttctgtatgc tttattaccg
     7381 gatggtacaa acaaagaaat ttggaaatct ggcaagattg attatgaagt aaatgataaa
     7441 gaattcacca aaactgtgct tgcgaaaaaa gtagataccg gaaaatatcc agaaggaacc
     7501 aagtttactt ttgcggaaat caattacgat aaagatggga atatcaatgg aaaacacaat
     7561 gaagatttga aagaaaaatc tcaaacctta acaccaaaag aagttccaac catactaagt
     7621 acgccgaaac aaccggaaac accaactgtt ccaagtggct ctcaagaatc tagtcccaca
     7681 gtgaagacct tccctcaaac cggggagaaa aattccaatg ttttactgtt cattggtttt
     7741 actttgattt ttgcgacggc gggctattat ttctggaatc gccggaacta aggtgatgag
     7801 atgatacaag taaatcctaa gaaccaacgt gcgcgaccgc ctcctaaaaa agtagtcgcg
     7861 ctatttttgt atccaaaact aacaatgaaa agaggaaaag aagatggaat tgaaatttgt
     7921 cgtgccagat atggctgaaa cctttggaaa gttaagttat gccggtgaag gagaaattat
     7981 aacagaagga tatggacgga atactacggt gattggtcgc agttatcatt tgtattccag
     8041 taagcaacgg gccgatgata ttgaggtggt agtagctgcg gaagccggtg aaaaggattt
     8101 tgatcaagac caaccgctaa aagccgtgaa tccccatttg gttgccaaag gctatgagat
     8161 tgagaatcgt gggtttactg attacgtgtt gtatgttgat gatttagtga aagcatagga
     8221 ggaaaagaag atgagattaa cagaaggtat tgtcgtagat tcaggtttaa catttgggaa
     8281 gttgcgtttt tccgcattac gccgagaagt acggaagcaa aatgaggatg gaacaattgg
     8341 taatgaggta aaagaacgaa cctataattt aaaatcctct gcacaagggc gaatgattca
     8401 agttagtatc ccagctaatg tacccttacg cgagtttgct tatgatgcag aggtagagtt
     8461 ggtcaatcca atcgtggata ccgttgccaa ttatgttttt cgagaaggaa ctaccgttaa
     8521 ttggttcatt aaggcggatg atttagtctt gaagcggcag ccgaatcaag gaaatcctac
     8581 gaaccaaaat gaaagaaaga aataggtgaa gattatggaa attaatgttg aacatatttt
     8641 agattgtctc gatcaatatg gaaaaggcga gctgactgag gaacaactcg ttaaagcatt
     8701 aacctctgat gaaaaaatgt ttctgattat acatcaaggt ttacttggag aaaatagcga
     8761 cagtgaagaa gactctgatg tactagactg gttaggagaa gaagagtctt tctttatagt
     8821 tgtcgaagta aatgaaaact tatgtcggca ggcagaatcc attttggaag aaattggtgt
     8881 ggagatgccg gatgctattg aaggcttttt aaatcaattg gttgaaacga aacaactccc
     8941 ctcctcgtag cagtaaatga ctagcataac tttttgaaat tgcctaatga aatcctattg
     9001 ggctttttcg attggaggtg gaaaccatca aaatgtacaa aggacatcgc atacgcgcag
     9061 gagatcagca cttggtttat cactttgttc ttggctggct actcgctctg ttcatcggtt
     9121 ggatgagcgt cttttatttt caagagttta gacaatttga tatttctaag ctatcacttt
     9181 ctactattga aatcgtttgg tctataaaag atttagtatg tctgcttgga agtctcgctt
     9241 tttcaggagc tatgatattg ctttatattc acttttttct tgatcattgg cgaagcttgt
     9301 ggcatcgaca aaagctagct cggatgattc tagagaacca ttggtatgaa gtgaaacaaa
     9361 ctcaaagtga aggctttttc aaagatttga atagtagccg aaccagagag actatcagtt
     9421 acttccccaa aatctgttat cgaatgaaag atggattact gtctattcgc gttcaaattt
     9481 cacttgggaa ataccaagat cagcttttaa aattggaaaa gaagttagaa agcggactgt
     9541 attgtgagtt agtagaaaag gaactcaaag actcctatgt ggagtatact ttactgtatg
     9601 atatgatcgc caatcgaatt gggatagacg aagtagtggc agaaaatggg actctgcgat
     9661 tgatgaaaaa tcaagtatgg gcttatgatt ctttacccca tatgttaatc gctggtggca
     9721 cgggtggagg gaagacctat ttcctcctca ccattatcga agcactattg aagtcagatg
     9781 cagaattgtt tatcctcgat cccaaaaatg cagatttagc tgatttaggt acggtgatgc
     9841 ctcatgttta ttcacaaaag gaagaaattt ctgcttgtgt ggaagatttc tatgaacgta
     9901 tgatggctcg tagcaaggca atgaaagaaa tgtctaacta caaaacagga gagaattatg
     9961 cctatcttgg acttccaccc aactttttaa tctttgatga atacgtggct tatatggaga
    10021 tgttaacgac gaaagaaagt gcggtgattt tgaataagct caaacaaatc gtgatgttgg
    10081 gtcgtcaatc tggtttcttt ctgattttgg cttgccaaag gccggatgcg aaatatttag
    10141 gagacggaat ccgcgatcaa ttcaactttc gcgtggcttt gggtcgtatg agtgaactcg
    10201 gatattccat gatgtttggg gaggtcgaaa aaaacttctt tatgaagcac atcaaaggtc
    10261 gaggttatgt ggatacaggt ggcagtgtga ttagtgagtt ttatacgcca cttgtaccaa
    10321 aagggtatga tttcttagat tcaattagta aattagaaaa gatgaatgat tgagtgatct
    10381 tcaatactga ctttatactt caagtaacgt ataatacttt tatatagtag gaagaaaggg
    10441 gataattaat atggaaagta atgattctta tttagagtat gcaaaagcaa ataaggataa
    10501 gtttatttct tatattatca aagggaaatc ccccgaagtt ggacgagacg cagtttttat
    10561 ggcagggagt cctggggctg gaaaatcaga ggttgccatt ggattagctg agaattatga
    10621 taaccatgtg attattgatg cggattactt tcgcacccag tttcctgatt ataatggaaa
    10681 aaactctagt ctctttcaaa aagcatcttc ttggttggta gagcaggcat ttagatatgt
    10741 cttagatcat ggctattctt ttattctgga tgcaactttt gcaatattaa gtgctgaaaa
    10801 aaatatctcg cgggcgttga aaaaacattt tcgagtgacg attttctatg tttatcaaga
    10861 ccctaaaatc gcttggaaat ttacacaaga acgtgaaatt gcagagggac gtcatgtgcc
    10921 gaaaaaggca tttattaacg cttttttcaa atcaagagag aacattgcaa aagtaaagag
    10981 taaacatcca gatgtattgc ttcatatcat aataaaagat tatacgaata atatttccga
    11041 agttcattat gctacggata atctagaatt atttttacca ctagggtata gtaggaaaga
    11101 tttggaggtt caattacatg actgagaaag aacaagtaac gaaaattgta aagaaataca
    11161 ataagagcat tgcggattta tcggaaaatg ctactgcaaa agagttcaaa acggtgatta
    11221 aatatgtagc cgatcaggcc aatgaaaaac aacggaaatt agttggatta aataaaaaat
    11281 agtaggacaa attaataatg tatgagccaa gagcaaaatg ttcttggctt ttttctttgc
    11341 aatgaatgag gtaatgtatg agatttttag atttattcgc cggtattggt ggctttcgtt
    11401 taggtatgga acaggcgagc catcattgta tcggtttttg tgaaattgat aaatttgcta
    11461 gacgtagtta taaagcaatt catgatacaa gtaaggaggt ggaaatgcat gacatcacaa
    11521 gtgtatcaga tgagtttatt caatccctcg gaccagtgga catcctttgc ggcggatttc
    11581 cgtgccaagc tttttcaatt gcgggaaagc ggcaaagatt ttccgatact cgaggtactt
    11641 tattctttga aatcgctcgg ttcaccactc ttctccgacc taagctttta ttccttgaga
    11701 acgtccgagg attgctcaat cacgaaggag gggctacgtt cgagacgatc ctccgaacgc
    11761 tggatggatt ggggtatgac gtggagtggt aggtgcttaa ctcaaaggcc tacattcccc
    11821 aaagccggga gcggatattc cttatcggac attctcgaga cgcatgtacc gaacaagtat
    11881 ttcctatcat tggaccgtct tcaacatctg atcaaaacat cagaaatttg gtaaatatca
    11941 atccttccaa tcgaggaatg ggtggacaag tctatggttc agatggcgta gcgccaacct
    12001 taacaggtga tgaaggaatc aaaatcgcac tgccagcaag ggatggaatc tctgtagcag
    12061 gactattacc gggaaagttt gaacaaggta atcgagttta tgaagttact ggaaccgccc
    12121 ccaccttgtc aacgaaacaa ggtggtacaa aaatcatgat tcgaaaaaat gaaacagaat
    12181 atcaagaggt gaagccagaa gacagtgtga atctggcttt tcctaattcc acaagtcgcc
    12241 gaggtcgtct gggaaaacag agtgttcata ccttactaac aggagaccaa caagcgatcg
    12301 tcacggatca gtatcaaatt cggaagctaa cacctagaga gtgttggcga cttcagggct
    12361 ttcccgattg ggcttttgat cgagattctc aagtcaattc agatagtcag ttgtataagc
    12421 aagccggaaa ctctgtaaca gttccggtca tttttgatat tgccagaaga ttaaaagagt
    12481 tggatgtaca tggtttatga tgagttgatt ggagaaattt attgggtgat tggaaagatt
    12541 cagtcagacc cagaattaga agaacaattg cgacggttaa aatttgatat tcgcaagaat
    12601 ggtgtcaaag tcgctggcga tccatattta atgaatgagg agacggatgc tcgaattgaa
    12661 ataaatcaag taattgcaga atttgagcgg attgcggacc aagcaaaaga accagatatt
    12721 cgtcaatact tgttagaaat gaaagcagag ttggaagtaa atggtattac agatgagtaa
    12781 cctaaaccaa cacaactgac tgttaggcgc tgaccgcgga ggattcgcga agcagaaatc
    12841 ctccgtggtg ctgtgcctgt tcatggacgg cgttagccga ccatgatgtc tcacccccgt
    12901 atctaacagg ggggtacaaa aacacaaaaa ataagtaagc aaccattaag aatgcttgtt
    12961 gtatcaaaga tagtaagtaa tttgtatagg tgttaactca tttgaaaaag ttaacacctt
    13021 gaatttggag gtgagaactt ggcacaacgg aatttagatt atcggctatt aaaagaccga
    13081 cgcaacgaat acggcgtttc acaaaataaa ttggctacgg cttgtggact tagtcggccg
    13141 tacttaaatc agatagaaaa tggtggcgta accgcatcta taaaaaccat gaggaaaatt
    13201 tttgaccaac tggaaagctt taatcccgat ttgcctttga cgttactgtt tgactatgta
    13261 aggattcgct ttcccacaac ggatgcacga aaaattattc aagaaattct ccatttgaaa
    13321 tttgagtata tgctccatga agattatgcc ttttactcct atcaagaaca gtatgtcatg
    13381 ggtgatattg tggtgatgtt gtctcatgaa gaagataaag gtgtgctttt agaattaaag
    13441 gggcgaggtt gccgacaatt tgaaactttt ttactcgctc aaaagcgtag ctggtacgac
    13501 tttttcgagg attgtctaaa ggccggtggc gtgatgaaac gcttggactt ggcaatcaat
    13561 gatcgagtgg ggctattgga tatacctgag ctaacgaaaa aatgtcagaa ggaagaatgt
    13621 atctccttgt ttcgtacctt taaaagttat cgttccgggg aacttttaaa ggctgatgaa
    13681 aaggacggca tgggcaatac cttatatatc ggcagtctca agagtgaggt ttatttctgt
    13741 ttgtatgaaa aagactatga acaatatatc aagttaggga ttccattaga ccaaactgag
    13801 acgaaaaatc gttttgagat tcgactgaaa aatgaccgtg cttttcatgc gattcaagat
    13861 ttgttaaaag gtcgtagcat tgagagcacc acgttttcca ttatcaatcg ttacttgcga
    13921 tttgcggata aagtagaagg taaaaggcga accaactggc ccttgaatga acaatggggg
    13981 cgttttattg gacggaatcg gaaagagatt caattaactt ccgagccaaa accgtatacc
    14041 attgaacgaa ccttgaattg gctaggccga caagtcgccc ctacgtggaa aatggctaag
    14101 gagttggatc gattgaatcg gacaacctat atccaggata tggtacagaa tgcacgctta
    14161 tcagaccgac ataaaaagat tttggagcaa caaagtatgg caattgaaaa tttgattata
    14221 tgaaaagagg aatcgtcatg ggaattgtaa aagatatttt tttggtattt ggtggcagta
    14281 tgcttggtgt tactgtgatg tgcttgatga atgcaagtgc agcagcggat cgagcaatgg
    14341 aaaagaaagg aaagtgacaa gatgaatttc ggacaaaatt t
//
LOCUS       DAFLWC010000075        14287 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.076, whole genome shotgun sequence.
ACCESSION   DAFLWC010000075 DAFLWC010000000
VERSION     DAFLWC010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14287
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.076"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(51..1598)
                     /locus_tag="L1V17_002191"
     CDS             complement(51..1598)
                     /locus_tag="L1V17_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBN1236938.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="L1V17_002192"
     CDS             complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="L1V17_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HBN1236939.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(2043..2237)
                     /locus_tag="L1V17_002193"
     CDS             complement(2043..2237)
                     /locus_tag="L1V17_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236940.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
     gene            complement(2463..3665)
                     /locus_tag="L1V17_002194"
     CDS             complement(2463..3665)
                     /locus_tag="L1V17_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1236941.1"
                     /translation="MKTKYPCVYQDKNGRFSYLVELGTDQVTGKRIQKKGTKDSLGKR
                     FSSAREAHKEVMRIKNEYMVVNGFANYDLTYKEFMEQSYVPHYKASVQKSTWSSRECG
                     LIQITEFFGDKKLREINVRDCENYRIWLLNDSGYSQAYSSLMYGMFRKSLDYAVTLQF
                     LNENISKRTKAIPKGKSIVPYWTKEEFEEVLAKIYKDDFYEHMCFLMIWLYYMTGVRV
                     SEGLALNWNDVDFKRKKLRVHHTLEMTNQKDFIRKPYTKTESGLRIISLDDDTIEVLK
                     KWKVIQKNHGVEQFILSYTDLPLYRSTVQRIIQRYAKLAKVPLIQGKGLRHSHVSYLI
                     NEFNADILVVSQRLGHSSPEITLKHYAHLWSRNDEGIAEQMTGNIKFTCATKSKVANF
                     NGNQAVKI"
     gene            complement(3668..3862)
                     /locus_tag="L1V17_002195"
     CDS             complement(3668..3862)
                     /locus_tag="L1V17_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBN1236942.1"
                     /translation="MKNTICRKDLEALGFKTHQATTIIRQAKTRMVNQGYPYYNNKRV
                     GVVPRQVIEEIIGVPLSQEE"
     gene            complement(3909..4757)
                     /locus_tag="L1V17_002196"
     CDS             complement(3909..4757)
                     /locus_tag="L1V17_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HBN1236943.1"
                     /translation="MQAYNQKIIETPTYIEIYDYEAIITPKRKTIENEVNLERKQKLA
                     WIYENDITLEKRKNYDELSAQGQYDSLKRKQKHYQSMRFEIARLVDTNFDNQTKFLTL
                     TFKENIQDIEYANNEFKKFIKRLNYDLYKTKKANLKYLATWEKQQRGAIHYHIILFDF
                     PFISFNRLTTIWGQGFVKINKIDVDSIENRGRYISKYFDKELELKEHKKKAFFKSRNL
                     KLPTVTKKMVKKPYDSTNQDILYTSEYIVRRPFFYNALALNELGSPEQVMDFQESTVH
                     YTKIKK"
     gene            complement(4962..5312)
                     /locus_tag="L1V17_002197"
     CDS             complement(4962..5312)
                     /locus_tag="L1V17_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236944.1"
                     /translation="MPIKITDLSLPKETLEKEYQVVNVTRWQKEGEILGWSYECILPK
                     LRYEKISVKVKSEHPVITPEELTQQGLAIITFTNLVIVPWGRSNGQFVSYGLSATADT
                     ATLIPRKQGTTTQN"
     gene            5907..6353
                     /locus_tag="L1V17_002198"
     CDS             5907..6353
                     /locus_tag="L1V17_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HBN1236945.1"
                     /translation="MKDYVVQITKEVLEESKTLNKLSSKAKEEAVTILSSGIIDYIEM
                     SGEIKYGEKDRIAKMVKESIKTFDVKQDLTFNDSYLIGKLINILGTDEDTELFLSSLS
                     MIFTDKHFSTRFGGEELVEIFQSMRPALIKLYREKTPDEFYDWFEK"
     gene            6977..7969
                     /locus_tag="L1V17_002199"
     CDS             6977..7969
                     /locus_tag="L1V17_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1236946.1"
                     /translation="MYWEEIELEKTLGPGGEIRAVQRDKKNISKWEKLKKQLRRDKWM
                     YLLLLPGIIMTFIFKYVPMYGAVIAFKDYNPMLGILESPWVGLDHFREFISSPNFTLL
                     LSNTLKISIYGLLLGFFPPIILALSLNQIINKKIKQKIQLILYAPNFISVVIIVGMLF
                     LFLSANGPINGLVEKVTGQPIMFMSNPAYFRTIYILSGIWQGIGWSSILYTATLAGVS
                     TDLYEAANIDGANILQKIWHIDLPALRPVMVISFILAAGGIMNVGYEKAYLMQTSMNI
                     PASEIISTYVYKVGLQSGDYAYSAAVGLFNMIINVVLLLIVNNITKRLNDGQGL"
     gene            7985..8869
                     /locus_tag="L1V17_002200"
     CDS             7985..8869
                     /locus_tag="L1V17_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1236947.1"
                     /translation="MNSALSKIDRQILWLNRVIVTFLVVITIVPLIYVLVASFMDPAT
                     LINKGISFNPKDWTIQGYQRVFADDSILRGFVNSLFYSFSFSLLTVFITMITAYPLSR
                     PNLAGKKIIMTFFVITMFVGGGLIPTYLLVKNLGMLDSVWAIIVPGAINVWNIILART
                     YFSALPKELSEAATIDGANDLQILFKVMLPLAKPIMFVLFLYAFVGQWNSYFDAMIYI
                     KDPDLQPLQLVLRNILIQNQPSQDMVGANTAMAEMKQIAELIKYATIVISSLPLIIMY
                     PFFQKYFDKGVLVGSVKG"
     gene            8918..10525
                     /locus_tag="L1V17_002201"
     CDS             8918..10525
                     /locus_tag="L1V17_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1236948.1"
                     /translation="MKAKWMLPIVFTSVLILGACGGSKEKSKSSPDYELENVSFPLKE
                     KVSLKMMSQSAPLAPNDPNDKLIFQRLEEETNLHIDWTNYSSDFAEKRNLDIASGDLP
                     DAIFNAAAGDYDLLNWAESGVIVPIEDLIEDYMPNLKKIFDENPEYRQMSTAPDGHIY
                     SMPWIEELGEGKESIHTVNGMAWINKEWLDNLGLEMPQTTDQLMTVLEAFKTQDPNGN
                     GEADEIPFSFINNGGNEDLKFLMGAFGLGDNDDHLVVDNDGQVQFTANKEGYKEAIKY
                     FNEMNNKGLIDKEAFEQDWNTYVAKGKEHKYGVYFTWDKANITGADDSYDVLPVLAGP
                     DGTKHVTRTNGMGFSRDRFVITSANKNLELTARWIDKMYEPLQSVQNNWGTYGDEAQA
                     NIFELKDGMLKHLPLEGTAPGELRQKTEAGGPLAVLDSYYGTVTTMPDDAKWRLDLMH
                     DTYLPYITEDNIYPRVFLEKEETDRLAKIETDMWDYIYRKRAEWITGGKIDEEWEEYL
                     AELERVGLEEWIQIKQTGYDNFLKGAQ"
     gene            10526..12010
                     /locus_tag="L1V17_002202"
     CDS             10526..12010
                     /locus_tag="L1V17_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016621147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HBN1236949.1"
                     /translation="MLVEETAILDKANRFIEMMRGKVNPQYRQNYHFSAPIGWINDPN
                     GFIYYKGHYHLFYQYYPYDSRWGPMHWGHARSSDLVHWEDLPVALAPDQPYDSGGCFS
                     GSAIERDGKLYLFYTGCQEIDGISHQHQCLAVSEDGIHFSKYSGNPVVAEKQLGENGL
                     IQEFRDPKVIVHNDGYYMVVATKSTQSTGRIVMFQSSDLYTWHFYSVLLEGTSEQGIM
                     WECPDLFHLDGRDVLIMSPIQIKKNGLEYHNISSTMACIGEVNWETGQMIVDNFHEMD
                     FGMDFYAPQTTRDPNGGRVMIAWMQMWDRTLPTHELGHLWAGSMSLPRELRVKKNRLV
                     QKPISTVYSHLVYQQGSENIAVTDTSVVFRNALSDSSYLHLVADLEKAEVFTIELLRS
                     KTDCLKLAYDTATQVFELDRQKLGRELTGAEEDPLNVRKVEVPLIDNQLVLEIFRDTS
                     SIEVFINGLEVMTATFYELEKARDILFHSIGESRIQAFETASVK"
     gene            12187..13179
                     /locus_tag="L1V17_002203"
     CDS             12187..13179
                     /locus_tag="L1V17_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005230454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1236950.1"
                     /translation="MKATMKDVAKLAGVGVGTVSRVLNNGSVKASTREKVEAAMTELN
                     YQPDFYARGLKMKHTNTVALILPTVWHPFFGEFAYHVETALERQNYKLYLCNSSGNSE
                     KEQEYIQMVSQNKVDGIIGITYSDIDEYISSNLPFVSIDRYFTEEVIYVTADNAAGGR
                     LAANELYRRGCQNVAYIGGYQETPNETKSRRKYFEIECRQLGISYKALDMLEPLDHLS
                     ERVTNFLLENPDIDGIFTINDPMALAVIDMLEKIGKNVPEDVQVIGFDGQKMTEGDPY
                     LVSTIAQPTKQMAEVAVAKLIAVINGETVEKRTVLPIEFGEGDTTKPLVRNDFA"
     gene            13231..14100
                     /locus_tag="L1V17_002204"
     CDS             13231..14100
                     /locus_tag="L1V17_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBN1236951.1"
                     /translation="MLYGGIEAGGTKFVCGIGNEQLQVIERKSFPTTTPEETMEQVFD
                     FFDKYKGNIASIGVGAFGPIDIQIESRTYGYITNTPKLAWQNYHFVGALENALSVPIY
                     WTTDVNAACYGEYMAGYGKGKNSVLYYTVGTGVGGGAVVDGKIVAGFSHPEMGHMLLQ
                     RHNEDQFEGICPFHHDCLEGLASGPAIEKRFGRKAQTISFDHPYWTIEADYLAQCVYN
                     TTLLYAPEVIILGGGVMKQPQLLELIRQSFKEKMGSYVDTPTLEEYLLTPRLADNAGL
                     IGCLALAIKKLNH"
BASE COUNT         4367 a         2434 c         2890 g         4596 t
ORIGIN      
        1 tacgtcaaat aacccgacct atagaataga atcgggaatg tttggcgttt ttagttacga
       61 gaaaaatgtt gttgtacatc cttgttccaa ggcaacagtt gatctaaagt ttctgctgaa
      121 agtacgggaa gatttggtat cttatcaaat agaaactcta gatactttac aggattcaat
      181 ccgttaagtt ctgctgtttt atatacactc agaatgattc ctgaagttcg tgctccttca
      241 agacttgtgg aatgcaacca atttttccgt cctatcacca gctctttgat atttcgctcc
      301 gcacgattat ttgtgagttc taaacgacca tcttcaaaaa taggttcaaa accacttcgt
      361 agtttacacg catattgaac ggctgcatcc aacttggatt ttgcaacagg atctatcgtt
      421 gccatccact cataaaaagc aataaataat ggacgcagtt cttgttgccg acagcttaat
      481 cgcttctcag gagaaaagtc tttccatttc ttttctagga caaaccattt atccaattgt
      541 ttgactgctt gagctgcggg aatatccgtg tttttctttc cttttggaat tgcttcgaaa
      601 aatttccgcc gaacatgcgc gaaacaatag acaagtcgta cactttccac ggcattatac
      661 ccgctatagc cgtcacagtg taaataccct gtaaactcct tgagaaaagt tttcggaaca
      721 tctccagcac gactttcgtc gtggtgataa taaacgatgg gatgctgact gtcttttcct
      781 gtacaaaact gccagtaata ggtatctgtt ttggcacttt caatcacacg ataacttgtt
      841 tcatccccgt gtagaatctc ttcttgatta agatagactc ttaatcgttc tcctaaaggg
      901 tctaacgcgt tttgcactgc tttaatatgc caattggtga tattatctct cgaaatatcc
      961 aacccatgtg tttgtttcca atagttctct tgccgatagg caggaacttt ctgaccaaat
     1021 ttcatccgga tcgtttccgc cactaaacta ttggaaccta agctattaga aatcaaaggt
     1081 ttaggaacga tcgctttttt aaaagaagaa agtccttctt tttcgcagct tttacaacaa
     1141 taggtatgtt gataatgggt gagacaatcc aacatagcct gatggaaacg aatttcttct
     1201 cgtacttttg tccgtccgat atctttcatc tgtgaaccgc aatgttcaca aaattgttct
     1261 tccaaaggaa ggagatgttc tttctctgtt ataggtaagt gtttgatttt gtctgctttc
     1321 gttcctacaa ctcgttgatg tccttttact ggaataatgg tggcagctgc ttctggaaca
     1381 cttacagaaa tttcttcatc actaaaaaga ttcaattgcc cattcgtttc ctcaaagaga
     1441 gtctctttag agcgtccaaa taatttgttg gttaaataat tgaccttttc attcaatagt
     1501 tggatttcag ttgtaagatt ctgaatggtt tgttgttgtg cttgattggt tttatgggct
     1561 tcttgaagca actgaagcaa cgtatctgta gtttccaaaa tttttcacca ccttgaatcg
     1621 aactgatttt gttacagaat accacaagaa acgcacaaga aataggggtt caacacattt
     1681 tttgtgttaa ccccccagct taaaaaactc ctttttttcc tggcaaaata gctcgaggtt
     1741 gatcgatact taatccttct aacaaccatc gaacctgttg gttcgttaag gttcgaactt
     1801 cgtctttcgt ccgaggccat tttaacttgc cgttttctat ccgcttataa cagagaagaa
     1861 aaccatcacc gtcccaatag agaagtttga aacggtcttg acggttcccg caaaataaaa
     1921 aaacggcatc ttcgtaaagc tcgagttgat actcttgttg aataagactg gcaagaccat
     1981 caattccttt tcgcaaatct gtttttccgc acacaatata aatatgtttg gtttgaagta
     2041 aatcataaag cattggacaa cagttctttc aaaatagctt gaagaatata attgttaata
     2101 ccgttataga tcaaaacttc agaaccattc tctcttttga tgcgcatcgc taacttggca
     2161 gccgcgggtt tacctttttc tggtgcactc ttttcgtttc ctaattggac aggaacaatc
     2221 tcatttaatt tatacataga aaacctccag acttcttgat agctcaagta tatcttgagg
     2281 tgcatttgtt agtaaggtac tgttctatgg ggcgcttacg ttgaaaaacg ttgatttatc
     2341 ggcattcccc atccatatta tatttacgtc ttattcccac tcaatatgag tagcctcgta
     2401 aagaagctat tatatcagtg ctttttcagc ctattcctca ttttggtagg gaaatggtag
     2461 ggttagattt ttactgcttg atttccatta aagtttgcaa ctttagattt tgttgcacag
     2521 gtaaatttaa tgtttcctgt catttgttct gcaattcctt catcattacg gctccataga
     2581 tgagcgtagt gctttaaagt gatttcaggg ctagaatggc ctaaccgttg cgacacgacc
     2641 agaatgtctg cgttaaactc attgattagg tagctaacat gagaatgacg taatcctttt
     2701 ccttgtatta ggggtacctt agctagtttg gcataacgct gaataattcg ttgaacagtt
     2761 gaacgataga gtgggaggtc agtgtagcta agaataaatt gttctacacc atgatttttt
     2821 tgaataactt tccacttttt tagcacttca attgtatcat cgtccagaga aatgatccgc
     2881 aagccgcttt cagtttttgt gtaaggtttc cgaataaaat ctttttgatt tgtcatttcc
     2941 aaggtgtgat gaaccctcaa ctttttacgt ttgaagtcca cgtcattcca attaagtgct
     3001 aatccttcgc ttacacgaac accagtcatg taatatagcc agatcattaa aaaacacata
     3061 tgttcgtaga aatcatcttt ataaattttt gccaaaactt cttcaaattc ttcttttgtc
     3121 cagtaaggaa cgattgattt tccttttgga attgcttttg ttcttttgga aatattctca
     3181 ttcagaaatt gcagggtgac cgcatagtct aatgatttac gaaacatacc gtacataagt
     3241 gaactgtatg cttgtgagta tccgctatcg ttcaataacc aaattcgata attttcacaa
     3301 tctcgcacat tgatttcacg aagcttctta tcaccgaaaa attcagtaat ctgaatcaat
     3361 ccacactcac gagaactcca agtacttttt tgtacgctag ctttgtagtg tggaacgtaa
     3421 gactgctcca taaattcttt gtaagttaaa tcataattcg caaatccatt tacaaccatg
     3481 tattcatttt ttatacgcat gacttctttg tgtgcttcac gagctgatga gaatcgtttt
     3541 cctagagaat cttttgttcc tttcttctgg atcctctttc cagtcacttg atctgttcct
     3601 aactcaacta gataagaaaa gcgaccattt ttatcttgat acacacaagg gtattttgtt
     3661 ttcatagtta ttcctcctgt gaaagaggaa cacctataat ttcttcaatt acttgtcggg
     3721 gtactacccc aactctttta ttattataat atggatatcc ctgatttacc attcttgttt
     3781 ttgcttgtcg gattattgtg gtagcttgat gtgttttaaa tcctagagcc tctaaatctt
     3841 ttcgacaaat tgtatttttc attgtataaa ctcactttca aagaaaacac tatcattggg
     3901 taatagtgtt atttctttat ttttgtataa tgaacggtac tttcttgaaa atccatcact
     3961 tgttcaggac ttcccaactc atttaaagct aaagcattgt aaaaaaatgg acgtctaact
     4021 atatattcgc ttgtatatag tatatcttga ttcgtggaat catagggttt ctttaccatc
     4081 tttttggtga cagttggtag tttgagattc cgggacttga aaaaagcttt tttcttatgc
     4141 tctttcaatt ccagctcttt atcgaaatat ttgctgatat agcgcccgcg attttcgata
     4201 ctgtctacat cgatcttgtt gatcttaacg aaaccctgac cccaaatcgt agttaaccgg
     4261 ttaaatgaga taaaggggaa atcaaacaag ataatatggt agtggattgc accgcgttgc
     4321 tgcttttccc acgtggcgag atactttaaa tttgcttttt tagttttata gaggtcataa
     4381 ttcagtcgtt tgataaattt tttaaattca ttatttgcat actcaatgtc ttgaatgttt
     4441 tctttgaaag tgagagttaa aaatttcgtt tgattgtcaa aattcgtgtc tacaaggcgg
     4501 gcaatctcaa atcgcatact ttgataatgt ttctgtttgc gttttaaact gtcatattgt
     4561 ccttgagcgg ataattcatc atagtttttt cttttttcaa gagtaatatc attttcataa
     4621 atccaagcta atttttgttt tcgttccaga tttacttcgt tttcgatcgt tttacgtttg
     4681 ggagtaatga ttgcttcata atcataaatt tcaatatacg tgggagtttc aatgattttc
     4741 tgattataag cttgcaaaaa tcatcactcc ttgttgcgta ttcgattgtc aaagaaccag
     4801 tcattttctc ctgatgttga tctataaatc aagttaaggg ggaaggcctg cgtagcagcc
     4861 cttctagcct atggggtgtt gggcggtctt aacggacaga aacggctctg tgggcgctgc
     4921 cccgccgttt cgtcctaacc acccaacact ccatagtata gttagttttg tgtagtggta
     4981 ccttgttttc tgggaatcaa agttgccgta tcagcggttg ccgataaccc ataactgaca
     5041 aattgtccat tcgagcgtcc ccaaggtaca atcaccaaat tggtaaatgt aattatggct
     5101 aaaccttgtt gggtaagttc ttccggcgtg atcacaggat gttcagattt gactttgaca
     5161 ctgatttttt cgtagcgaag ttttggtagg atacattcgt agctccaacc tagaatttcg
     5221 ccctcctttt gccagcgagt gacattgacg acttggtatt ctttttcgag tgtttctttt
     5281 ggtaaactga gatcggtaat ttttattggc atcacaattc tcctttttta tacgaaagtt
     5341 tatacgattt gattaaaaaa tatagatggc catctacgac ttgtattata tacgagaact
     5401 tatacgtagt caagagattt tctaaaaaaa tatatacgat tttttatacg agtgttataa
     5461 tgaaaaaaat gataaggagg aatttgaata tgtttggttt agtacaacct aataaagtga
     5521 aggtgggcca acgaatcaaa gaaataaaag acggaatgtc tctctctttt acagaattag
     5581 ggaatcgatt aggtttaaaa aagccgacga tcagttccta cgttcaaggc tatgcgttgg
     5641 ctcctaagag tgtgatcaac caattatcta gtatcagcgg aaaacctgtc ggctggtttt
     5701 attttgggca tgtggaagaa tatatccgag agtatttgtt tctcattggt cagaaaaaaa
     5761 tagtggacga ttatcctgaa atcattgaga aaataaagca agaattttat acgggcgagt
     5821 tcaaaaatcc tgcttgggag aatgagctag gctatccttt ggaggaattt atccaagaat
     5881 gttttgtaga atattcgagt gaaatcatga aggactatgt cgtacagatt acgaaagagg
     5941 tacttgaaga atccaaaacg ctaaacaaac tatcatcaaa agcaaaagaa gaagctgtca
     6001 cgattctttc atctgggatc attgactata tcgagatgag tggtgagatc aagtatggag
     6061 agaaagatcg cattgcgaaa atggtgaaag aatcaataaa aacctttgat gtgaaacaag
     6121 acctgacatt taatgattcc tatttgattg gaaagttgat caatattctt ggtacagatg
     6181 aagatacgga gctgtttctt tcttctttat caatgatatt tactgataag catttttcca
     6241 ctcgatttgg tggggaagaa ttagtcgaaa tatttcaatc gatgcgacca gcgttaatca
     6301 aactctatcg ggagaaaaca ccagatgaat tttatgattg gtttgagaag taaaataaga
     6361 aaagtggctt agattacaag ttggtgaaaa aatttttttc agcataacat cagtaatcta
     6421 taaaggggtt gttgattata ctgtagaagt taagtactca agagattttt tgtacgtaaa
     6481 caaagcaaaa aagggtgcag tttcactaga aaatgtactc ttttttgtga tttttcttag
     6541 ttatagagtt tttttgaaac tttaaaaatg agaaaacata ttgattttaa agagtgtaga
     6601 catagcttct tttgctaaat agattaaact tactggtgag tggtcttgaa catactttta
     6661 aatcacattt tactgagttt tattggattt tataattcat tggaaacctc gtacttaatc
     6721 tgtttttatc tatcgactag aatctgtata tattccagct atcaatgagg ccgcagaaaa
     6781 gggtgcttaa aaataatctg ttgtttaaaa tattattatc agaatactta gatacaaaat
     6841 tctggcacaa agtaaaaaaa atattgactt aaaaaaatgg atatggtaat ctataaacga
     6901 aaatagtggt aacgtttcca aaatgcatct tcgttaaatt tttatttttt taaacgaaaa
     6961 tggaaacgtt tctaaaatgt attgggagga gattgaattg gaaaagacat tgggaccagg
     7021 tggtgagata agggcggtac aacgggataa aaaaaatatt tcgaagtggg aaaaattaaa
     7081 gaaacagttg cggcgtgata agtggatgta cttgttgctc ttaccaggta tcatcatgac
     7141 gtttatcttt aagtatgtgc caatgtacgg tgctgtgatt gcatttaaag actataatcc
     7201 tatgctagga attttggaaa gtccttgggt aggactagat cactttaggg aatttatcag
     7261 ttcaccaaat tttacgcttt tgctgagcaa cacattaaaa attagtattt atggtttatt
     7321 gttaggtttt tttccaccaa ttattttagc actgagcttg aatcaaatta tcaataaaaa
     7381 aataaaacag aaaatccagt tgattctata tgcgccgaat tttatctcag tagttattat
     7441 tgtggggatg ctgtttttgt tcctatccgc aaatggacct attaatgggt tagtagaaaa
     7501 ggttacgggg caaccaatta tgttcatgtc taatccagct tatttcagaa cgatttatat
     7561 tttatcggga atttggcaag gaatcggctg gtcatccatt ctttacaccg caacgctggc
     7621 gggagtcagt accgatttat atgaggcagc aaatatcgat ggggcaaata ttttacaaaa
     7681 gatttggcat atcgatttgc ctgcattgag gcctgtgatg gtgatcagct tcatcttggc
     7741 cgccggcggt attatgaatg taggatatga aaaagcctac ttgatgcaaa cttcaatgaa
     7801 catccctgcc tcagaaatca tttccactta tgtatacaaa gtcggcttgc aatcaggtga
     7861 ttatgcctac tctgctgctg ttggtctgtt caatatgatt attaatgtcg ttttattact
     7921 gattgtcaac aatataacca agcggctaaa cgatggtcaa ggcttgtaat gaaaggagaa
     7981 aattatgaat agtgctttat caaaaatcga ccgtcaaatc ttatggttga atcgagtgat
     8041 tgtaactttt ttagtcgtca tcaccattgt tccgctgatt tatgtactgg tagcttcttt
     8101 tatggaccca gctactttga tcaataaagg tataagcttc aatccgaaag attggacaat
     8161 acagggatat caacgggtat ttgcagatga ttccatttta cgcggttttg taaattcgtt
     8221 gttttactct tttagcttca gcttattgac tgtatttatt acgatgatca ctgcgtatcc
     8281 tttgtctcga cctaacttgg cggggaaaaa gattattatg actttttttg tcattacaat
     8341 gttcgtgggt ggtggcttga tacctaccta tttattggta aagaacttgg gcatgttaga
     8401 tagtgtatgg gcgattatcg taccaggtgc tataaatgtg tggaatatta tcttagcccg
     8461 tacctatttt agtgctttgc caaaagaact ttctgaagct gctactatcg atggcgccaa
     8521 tgacttgcaa atactgttca aagtcatgct tccattagcg aaaccaatta tgttcgtatt
     8581 gtttttatat gcctttgttg ggcaatggaa ctcatacttt gatgccatga tttacatcaa
     8641 agatcccgac ttacagccgt tgcaactcgt attaagaaat attttgatcc aaaaccaacc
     8701 ttcacaagac atggtgggag ccaatactgc catggcagaa atgaaacaaa ttgctgagtt
     8761 gatcaaatac gcaacgatcg tcatttctag tctgccatta atcataatgt atcctttctt
     8821 ccaaaaatat tttgataaag gtgttttagt tggttctgtt aaagggtaag tattgttcac
     8881 tatttgtatg aataaaaatt ataaaggaga ttttaagatg aaagcaaaat ggatgctgcc
     8941 aatcgttttt acttccgtac taattttggg ggcttgtgga ggctcaaaag aaaagagtaa
     9001 atcaagccct gattatgaac tagaaaatgt ctcttttcca ttgaaagaaa aagtatcttt
     9061 aaaaatgatg tctcaaagtg cccctttggc tcccaatgat cctaatgaca aattgatttt
     9121 ccaacgatta gaagaagaga ccaatctcca tattgattgg acaaactaca gtagtgattt
     9181 tgccgaaaaa agaaatttgg atatcgctag tggtgattta ccagatgcca tcttcaacgc
     9241 cgctgcaggt gactatgatt tattaaactg ggcggaaagt ggcgttattg taccgattga
     9301 agatttgatc gaagattata tgccaaatct gaagaaaatt tttgatgaaa accccgaata
     9361 ccgacaaatg tctactgcac ctgatggtca catttactct atgccttgga ttgaagaatt
     9421 aggcgaagga aaagagtcga ttcatacagt aaatgggatg gcttggatca acaaggagtg
     9481 gttggataat ttgggtcttg aaatgccgca aaccactgat cagttgatga ctgtgttgga
     9541 ggctttcaag acgcaagatc caaatggtaa tggtgaagca gatgaaattc cttttagctt
     9601 tattaacaat ggaggaaacg aagacttaaa atttttaatg ggggcattcg gtctaggtga
     9661 taatgatgac cacttagtcg ttgataacga tggtcaggta caatttactg ctaacaaaga
     9721 agggtataaa gaagccatca aatatttcaa tgaaatgaat aataaaggtc ttattgataa
     9781 agaggctttc gaacaagatt ggaatacgta tgttgccaaa gggaaagaac ataagtatgg
     9841 cgtgtacttt acttgggata aagcaaatat cacgggtgca gatgatagtt atgacgtctt
     9901 gccagtctta gcgggaccag atggaacgaa acatgttact cgtacgaatg gcatgggttt
     9961 ctcaagagat cgtttcgtaa ttactagtgc gaataaaaac ttggaactta cagctaggtg
    10021 gatagataaa atgtatgaac cgttacagtc tgtccaaaat aactggggaa cctacggtga
    10081 tgaagcacag gcgaatattt ttgaattaaa ggatggtatg ttaaaacatt tgcctttaga
    10141 ggggacagca ccgggggaac taagacaaaa aaccgaagct ggaggaccat tagcagttct
    10201 tgattcttat tacggcacag tcactactat gccagatgat gcgaagtggc gtttagattt
    10261 gatgcatgac acgtatttgc catatattac agaagacaat atctatccac gtgtcttttt
    10321 agaaaaagaa gaaacagatc gattagcaaa aatcgaaacg gatatgtggg attacatcta
    10381 tcgcaaaaga gcagagtgga tcaccggcgg taaaatcgat gaagaatggg aagaatacct
    10441 tgctgaattg gaacgtgtag gtttggaaga atggattcaa ataaaacaaa ctggctatga
    10501 taattttttg aagggagcac aataagtgtt agtagaagaa acggcgattt tggataaagc
    10561 aaatcgattt attgaaatga tgcgaggaaa agttaaccct cagtatcgac aaaactatca
    10621 tttttccgca cccatcgggt ggataaatga ccccaatggg tttatatatt acaaagggca
    10681 ttaccatctc ttctatcaat actatcctta cgatagtcga tgggggccca tgcattgggg
    10741 gcatgcgcgc agtagtgatt tggtccattg ggaagatcta ccagtagcgt tagccccaga
    10801 tcaaccttat gacagcggcg ggtgtttctc aggaagtgca attgaaagag acggaaaact
    10861 atatttattt tatacaggct gtcaagaaat tgatggtatt agccatcagc atcaatgttt
    10921 ggcggtctct gaagatggta ttcattttag caaatacagt ggtaatcctg tggtagcaga
    10981 aaaacagcta ggtgaaaatg ggctaataca agaatttcgt gatcctaaag taattgttca
    11041 caacgatggt tactatatgg tagtagctac taaatctaca cagtctactg gtagaatagt
    11101 gatgtttcaa tcgtcagatt tgtatacttg gcacttttac tctgtgctgc tagaagggac
    11161 ttcagagcaa ggaataatgt gggaatgtcc tgatttattc catttagacg gacgagatgt
    11221 cttaatcatg tctccgatac aaatcaagaa gaacggactg gaatatcata atatcagttc
    11281 taccatggct tgtattggtg aggtaaactg ggaaacaggt cagatgatag ttgataattt
    11341 ccatgaaatg gattttggaa tggattttta tgcaccacaa acaacaagag atcctaatgg
    11401 tggacgggtg atgattgctt ggatgcagat gtgggatcgt acattgccta cacatgagtt
    11461 aggccatctt tgggcaggct ctatgagttt gccccgagag ttaagagtga aaaaaaatcg
    11521 attggtacaa aaacccatct caactgtata tagtcattta gtttatcaac aaggcagtga
    11581 aaatattgca gtgactgaca catcagtcgt atttcgaaac gcgctgtctg attcttcata
    11641 tttacatcta gtcgcagatt tggagaaagc tgaagttttt acaattgaat tactgcggtc
    11701 taagacggat tgtctcaaac tagcctatga cactgctaca caggtttttg aattggatcg
    11761 tcagaaacta ggaagagagc ttacaggggc ggaagaagac cctctgaatg tacgaaaagt
    11821 tgaagtacct ttgattgata atcagctcgt tcttgagatt tttagagata cctcatcaat
    11881 tgaagtcttt attaatgggt tagaagttat gacggctact ttctatgagc tggaaaaagc
    11941 tcgagatatc ttgtttcatt cgatcggaga aagtcgtatt caagcttttg aaacagcgag
    12001 tgtgaaataa atgtttgatt gcttaggcga tgaatcaatt atttaatagg ttttgaagga
    12061 taatgttttt agaaaagaac agatagctag atttcccatg gatttgctat tagtattttg
    12121 aaaaaattag taatttatga caaaattcat tatactaaac ttgtgcagaa atgtgaggga
    12181 tcaactatga aagcaacaat gaaagatgtc gcaaaattag caggtgttgg agtaggaact
    12241 gtttcccggg tattgaataa cggttctgtt aaagcttcta ctagagaaaa agttgaagca
    12301 gcaatgacag agttaaacta tcaaccagat ttttatgccc gggggttaaa gatgaagcat
    12361 acgaacacgg ttgctttgat tctacccacg gtatggcatc cattttttgg cgaatttgcc
    12421 taccatgtag aaacagcatt agaaagacaa aactacaagc tttatttgtg taactccagt
    12481 ggtaatagtg aaaaagaaca agaatatatc cagatggtca gccaaaataa agtagacggc
    12541 atcattggaa ttacttattc agatatcgat gaatacattt cgagtaatct gccttttgtt
    12601 agtattgacc gttatttcac tgaagaggtg atttatgtga ccgctgacaa tgcggccggt
    12661 ggacgtttgg ctgcaaatga actttatcgc cgaggatgtc agaatgtagc atatatcggt
    12721 gggtaccaag aaacaccgaa tgaaacgaag agtcgtcgaa aatattttga aatcgagtgc
    12781 cgtcaactgg ggatttccta taaagcgtta gatatgttag aacctttaga ccatctctca
    12841 gaacgtgtaa caaatttttt gttagagaat cccgatatcg atgggatttt tacgatcaac
    12901 gatccaatgg cattagctgt cattgatatg cttgaaaaaa tagggaaaaa cgtaccagag
    12961 gatgtccaag ttatcggatt tgatggtcaa aagatgacag aaggagatcc ttatctagtc
    13021 tcaacgattg cccaacctac aaagcaaatg gcggaagtgg cagtggcaaa attaattgct
    13081 gtcattaatg gagagacagt agaaaaacgt accgtattgc cgattgaatt tggcgaaggt
    13141 gacacaacga aacctttagt gagaaacgat tttgcttagt gcaaatacgt ttcttttttt
    13201 gaaaatgagt gaatgaaagg tgtagataaa atgttatatg gtggaataga agccggtgga
    13261 acaaagtttg tctgtgggat tggtaatgaa caattacaag tgatagaacg gaaaagtttt
    13321 cctaccacaa caccagaaga aacgatggag caagtgtttg atttctttga taagtacaaa
    13381 ggaaatatcg catcaattgg tgtaggagca tttgggccta ttgatattca aatcgaatca
    13441 agaacttacg gatatatcac caacacaccg aagttagctt ggcaaaatta tcattttgta
    13501 ggagctttgg aaaacgcctt gtcggttccc atctattgga ctaccgatgt aaatgctgct
    13561 tgttatggag aatatatggc agggtatgga aaaggtaaaa atagtgttct gtattacacc
    13621 gttggtacag gtgttggtgg tggtgctgta gtggatggga aaatagtcgc aggttttagt
    13681 catcctgaaa tgggacatat gctcttacaa cgtcataatg aagatcaatt tgaaggaatc
    13741 tgtccttttc atcatgattg tttggaaggg ttagcatcag gacctgcgat tgaaaaacgc
    13801 tttggaagaa aagcccagac tatctcattt gatcatcctt attggacgat tgaggcagat
    13861 tatcttgctc agtgtgtgta taacacaacg ttactatatg caccggaagt aataatttta
    13921 ggcgggggtg taatgaaaca gccgcaacta ctcgagttga ttcgccaatc gtttaaagaa
    13981 aaaatgggtt cctacgtgga tacgcctact ctcgaagaat atctactaac tccaaggctt
    14041 gctgacaatg cgggcttgat tggctgccta gctttagcaa taaagaaact caatcattag
    14101 aatagtattt attagaacta ttcataacat accggaagtt taaaagggta ttctgaaact
    14161 taaatagtct caattcattc ttctttcttg agaatctgag tagagacttt tattctgttt
    14221 caaattaata taattacgaa atgatattga gtacaagaaa gttcttttta ccagatcttt
    14281 taaatcg
//
LOCUS       DAFLWC010000076        13970 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.077, whole genome shotgun sequence.
ACCESSION   DAFLWC010000076 DAFLWC010000000
VERSION     DAFLWC010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13970
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.077"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            60..1178
                     /locus_tag="L1V17_002205"
     CDS             60..1178
                     /locus_tag="L1V17_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236952.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            1681..2001
                     /locus_tag="L1V17_002206"
     CDS             1681..2001
                     /locus_tag="L1V17_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236953.1"
                     /translation="MKKRLLWCLLSLSLSLTSQPVFAEETQRFPITGTRLYKNVYVQT
                     PDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            2454..2654
                     /locus_tag="L1V17_002207"
     CDS             2454..2654
                     /locus_tag="L1V17_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBN1236954.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            2801..5590
                     /locus_tag="L1V17_002208"
     CDS             2801..5590
                     /locus_tag="L1V17_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBN1236955.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            5637..6164
                     /locus_tag="L1V17_002209"
     CDS             5637..6164
                     /locus_tag="L1V17_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HBN1236956.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            6185..7375
                     /locus_tag="L1V17_002210"
     CDS             6185..7375
                     /locus_tag="L1V17_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBN1236957.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            7415..8713
                     /gene="asnS"
                     /locus_tag="L1V17_002211"
     CDS             7415..8713
                     /gene="asnS"
                     /locus_tag="L1V17_002211"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBN1236958.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            9889..10563
                     /locus_tag="L1V17_002212"
     CDS             9889..10563
                     /locus_tag="L1V17_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBN1236959.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     KFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            10560..10901
                     /locus_tag="L1V17_002213"
     CDS             10560..10901
                     /locus_tag="L1V17_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236960.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERVDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            10931..11290
                     /locus_tag="L1V17_002214"
     CDS             10931..11290
                     /locus_tag="L1V17_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HBN1236961.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            11815..13899
                     /gene="cadA"
                     /locus_tag="L1V17_002215"
     CDS             11815..13899
                     /gene="cadA"
                     /locus_tag="L1V17_002215"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBN1236962.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKKFMQYIASAEQFSTHPIAQSVLEGYAGPLLP
                     TTNIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPLSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKKEDE"
BASE COUNT         4652 a         2423 c         3028 g         3867 t
ORIGIN      
        1 gtgttgtggt agactttaga tagaaacaaa ggaatgattt ttttaggagg ggtacgttta
       61 tggcaaaaaa ggataaagaa ttattgtcac aattgacttc agaaggcgct aaaggaccat
      121 tcgtcacgat catgctgaat acgcatgtcg cccatcaaga tgtggaaaaa gatcagatca
      181 aattcaaaaa ttttgcgaaa gaagcaaaga aacgttttga gaaaaaatat tccgaacatg
      241 actggtcccc gttccaagaa aaaattgaaa atttgttagg agatccttcg ttttggcgta
      301 gtgcaactac gagtgtagcg gtcattataa ctgctgacca aacctatatc catcgtttga
      361 gtatcccggt agacgatcaa tactatgtaa gtgatcttcc ttatttactg gctattatca
      421 aaaatgggca gttcaactat tcttattatt tattgggatt gaaccgcgac tccatgaaat
      481 tgtatgaagt cagcaacaaa caagtaaaag aagtatctct accagaaggg gcaccggttg
      541 atgtcgttac tgcattggga tctgaactga caggtggcgg tttgaacttc tcttctaatg
      601 gaggaggcgg agcccgagat ggagtaactt tccatggcgt aaatccaaaa gatgaagaag
      661 tagagatcga ttgggtcaac tattaccaag cagttgatac gtacttgaag gattctttcg
      721 aaaatccaga acaatggccg atttatttat ttgctctacc agaaaatcag acgatgttca
      781 aaaaaattgc taaaaatccc tattattgtg cagacgttgc gatttctgct tctcctgcgc
      841 agctatcctt tagagatatc gaagaagggg cgaagaagct gtcaagtgaa ctcgcagctc
      901 aagaatcaaa agaatacaat aaactcttag ataagaaatt catcgatcag ttagttgata
      961 tcgttccagc tgcgaaagaa ggaaaagtgt cacatttatt tatcgctacg tcaaacttag
     1021 ctgatggttt cggtgaagat cctgaaacag aatatgatcg gcgtcaagtg ttgaatgcat
     1081 tagcagatga tgtgatcatt aatggcggaa aagtgtttat tttggatcaa aaagatgcgc
     1141 cagatgaaaa gagtctgaca gcgattcttc gttattaaaa gaggttgtga aatcagtgtt
     1201 ttgacctgag tattagagaa acaaacggaa aaatagtttc acatattttg ccgttttttg
     1261 agctaatacc gaaggtcagc tgattaaaca ccgtgtatga gaggttgtga aaaagctgtt
     1321 ctgcatcaag taataagaac agcaagcaaa aatagctctt catatttttt gtttggtggg
     1381 cttattaccg cagatgcaag cttttgaaca ccgtttaagg aagaggttgt gacagaagtg
     1441 gtcagcttca agaaataaga agagattgac aaaaattatt tctcaaattt ttgtgaaatt
     1501 tcggcttatt tccgaagaag ctacttctgg aacaccgttt aaaaaagagg ttgtgacgtg
     1561 gtcacgacct ctttttgacg attatgatac aaaaaacatc atttatgaac aaaatgtgaa
     1621 taacgggcgt tcttgagata tgattttaat tgggaaaaac ttatcgataa ggaggtcttt
     1681 atgaaaaaaa gactgttatg gtgtttgctg tctctatccc taagtttaac aagtcagcca
     1741 gtttttgctg aagaaacaca gcggtttcct attacaggca cacgtctgta caaaaatgtt
     1801 tatgtacaga caccagatct tgattctgcg attcctgaaa cagaagaacg gtctttgcag
     1861 ccaagatttg gttacttttg gtactgtccg acctgtgatt atgaaagttg ctggcatttc
     1921 ttacattcta cagctgcagc ttttgctttt actcatactc agaaatatga tggacatcat
     1981 cctgttattt atgaggtata gatatgagca aaaaagaaaa actaatctcg ttggtcgtat
     2041 tggtttgcct tgttcttctg gtaactgtca taggctatca gaaataccat gagaacatca
     2101 gacctactaa agaatcttcc ccagcctcga ccgttgaaac agaaccgata agtagtcaga
     2161 aagaataatt tttttagttt aaaaaagaac atcagagcaa aaaaacacca actgaacaat
     2221 atgtcgttta ttttaaaaaa aagttcggtt tttcacttta tgtaatcgct gagaaaactt
     2281 tttttaataa aaaaagtcga aaaactctag cttttttgta aacggtatga tatactatag
     2341 gagtagtttt tgttcggtaa tctgtggtag cttgtttcaa ataaacatct tccagatata
     2401 caccattcaa gtaattgcaa aatatgtgtt gatacacaag gaggattttt attatggaaa
     2461 caggtacagt aaaatggttt aactcagaaa aaggatttgg attcatcact gcagaaaacg
     2521 gaaacgatgt attcgttcat ttctcagcta tccaaggcga cggattcaaa actttagaag
     2581 aaggccaagc agtaactttc gatgttgaag aaggccaacg cggacctcaa gcaacaaacg
     2641 ttactaaagc ttaattaacc tatactaaaa aataaacgcc cagacatttg cgtgtctggg
     2701 cgtttttgtc tattttcttt aaaaagcgat gagagtattt ttctgcactt tgtagtataa
     2761 tttcaaaaga acattagagg caggagaaga ggaagatatt ttgaaaccaa gaacttatgc
     2821 agtcgttgat atcgaaacga ctgggacgaa tccaaaagaa gatcggatca tccaatttgg
     2881 ctgcgtcatg attgaatcag gtcggatcac ttcacgtttt tcgatcgata ttcatccagg
     2941 gcggaagatt tcaaaacaaa tccagcattt aacagggatc acgaatcaac gcgtccaaaa
     3001 agcgccttat ttcgaagatg tcgcccaaac gatttacaat cttttggcag acaccatatt
     3061 tgtcgcgcat aatatttatt ttgattataa ttttttgaac catgaactca tgcgatgcgg
     3121 acttcctagt ttgaagatac caggcatcga tacagtagaa cttgcacaaa ttttcttgcc
     3181 gacggaacca agctttcgct tagctgattt gtcagaaagc cttggattta ttcatgagaa
     3241 tcctcatcag gcagatagtg atgccgaagt gacaggtcaa cttcttttgc tgatcgaaga
     3301 acggatgaga aaattgccaa tcatcacgtt agagcagatt gcgcgattaa gtagacacac
     3361 aggtatggat acgagtcgtt tcatttatca tgtgattgaa gaaatgaaag aaaaaccaga
     3421 gccacttgat ccctcattag aaatcgtcga tgggctagct ttgcagaaaa aagaagtgga
     3481 actattcaca tccgtccatt atggcgagcg gacatatcca agaaaaaaac aagcaaaaga
     3541 aaaaatgttt ggtaaaacac tgatgtatcg aaaagaacag aacagactga tgaatgcggt
     3601 ctacgaccat ttcacaaaag atgaatcaaa agatttgatg atcgaagcag ctacaggaat
     3661 gggtaaaaca atcggttatc tgctgccatt gagttatttg gctacacctg aaaaacccgc
     3721 tgtcatcagt accgtttcgc tagttttgca gcagcagatc atagaaaaag acattccatt
     3781 gctgaatcaa ttgctagatc agcccataca acctgtaatt atcaaaagct atcgccacta
     3841 tattgatttg cagcgtttta aaggcacact tgtggaaccg ccagaacaaa aacaatatgc
     3901 tttgtatcaa atggcggtct tagtttggct gacgcaaacg aagactggtg atttggatga
     3961 attacattta acaaatttga accattcatt ctttgcagat atcgcgcaca gaggtattgg
     4021 atttttagca agaaatcagt cattttacga acaagacttt gttcgtttct tgcaaaagaa
     4081 aatcaggcaa agtaattttt tgattgtcaa tcatgcgttt ttagtacaag aaacacagcg
     4141 aaaagaacca ttgcttccag ctagtccatt tttgttgatc gatgaagtac atcatttgcc
     4201 ggaaatcgct gaaaaagtaa atgacaaacg attaagtatt aactatttcc ataaacaaat
     4261 ccagcaatta gaagaaccaa atcagctgtt tgaccgaata caaagctatt taccgaaaga
     4321 acatgaagcc ttacgctggt tatcgattta tcgagaagaa ctttctgcgc tatgcgaagc
     4381 acagatttgt atggcagaag gattaatgag tttagtgagc ggcaagcaac ctaacggaca
     4441 gtatccagaa gaagtcatga tgacaaaaga gatgttggat cagctgccac tggaatctgg
     4501 gacagccatt gatcacctgc agctttttta tcaggagatc cagcagctac agtcacaaat
     4561 gcgtctgact tttgagatta tccaagaaag ctggacaaac cagatgcgga tcgatttagc
     4621 aagtttatat agcctatttg atcaattaga caagcaatac ttgctgatgg atcaatggct
     4681 ggaagactgg cgagatcatt tgatccattg gttcgttcct gggaacacag cgcagcagat
     4741 gatttttcat ctccatgatt ttcaagcggc tatgttgccg tcgactgttt ggtatcctcg
     4801 atatgatcgt attctttata ttggaggaac gctgaagatc ggccctaatc gacactatct
     4861 ctctaagagg cttggcattg aagcagcacc tcttaaagtg attgcctctc cttatgatta
     4921 tgagaaacag gcaaggatct atgtgccaaa agaggcacct gccgtccatc aagtcagcaa
     4981 tcaagcatat atcgattatt tagagacagc acttacaggt ctgatcgaac aagaagatcg
     5041 gccaatactt gtgttattca cttctcatga tgttttgcag aaggtctatc agaaaatgca
     5101 tctgtctatg ctagaaaaag gacgagaaat actagctcaa gggtttggtg gaagccggga
     5161 gaagcttttg aaacgcttca ttttgtcaga aaaaagcgta ttgtttggcg ctgacagctt
     5221 ttgggaaggt gtagatttgc ctggagatgc tttgcagatc gttgtagtca cacgtttacc
     5281 cttcgataat ccgcttcgcc cgatggtcaa agctaggaac gcttatttag aatcagaggg
     5341 gatcaatcct ttttaccagg aatccgtacc taaagcagct ttgaagttac gccaagcatt
     5401 aggtcgcttg ataaggacgg agacagatcg tggcgtattg cttattttgg atcgaagact
     5461 agtcactgca aaatatggcg cacggatcat ccatgcatta ccgaaaaaag taccgatcaa
     5521 agagctagct atggaggaaa tctatcagga tatccatgaa ttcttaaaga aaaatgaaga
     5581 aggaagttag aggagctgtc ttttttcata attaaaatct gctataatga aaaggaatga
     5641 agataaagga gcgacgaccc ttgaagaaaa aacagacaaa ggaaaaaacg attaatcgcg
     5701 tgttacttgg cttgatcgta tttttattag cggtcatcgt gatcagctcg attttttact
     5761 tgcgttccag tcgtccggcg gtgcaggcga agaaagaagc agtagaaatc gcaaagaaat
     5821 atgcaaatct tgaggaaacc gatcattttt attggtttac tcgaaagaag acatactttt
     5881 cactgacagg tacaaatgat aaaggaaaag aaatcgccgt tatcattcct aaatctggtg
     5941 aaaaagtaaa agtattggat caaacaaagg gactgactga aaacgaagca aaacagacaa
     6001 ttgctgcggc ccatcctgaa atccaaatcg aaaaagctgc tttagggatg tatgatgatc
     6061 agcctgtgtg ggaagtagta ggaaaagaaa caaatgggaa actgaattat tacctgattg
     6121 gctttgaatc tggagatgaa gtcaagacaa tcaagggaat ttaaaaggta aaggaatgaa
     6181 tgggatggag ttatcaaaaa gaacaaaacg attagaaccg tctgtcactt tggcagctgc
     6241 ggcaaaggcc aaggcattaa aagcaaaagg cagagatgtg ctgagtttga ctgtgggaga
     6301 accggatttt gcgacaccag aaaacatcca agaagcagca atcgaagcaa tccgcaatgg
     6361 gaaagctagc tattatacac caacagcagg aatcccagag cttcgacagg caatcgttga
     6421 ttatctgaag aaaaactatg gacttgtcta tgaaccttca caaacagtcg taacagacgg
     6481 agcgaaattt gctttgtata cccttttcca aacgatcctt gacccgcaag atgaagtcat
     6541 cattcctgtg ccttactggg tcagttacgg tgagcaagta aaactggcag aaggacttcc
     6601 tgtctttgtg aaaggggaag aatccaatag ctggaaagtt actgttgaac agctagaaca
     6661 agcacgttca gaaaaaacaa aagccgtaat catcaattct ccatcgaatc cgactggaat
     6721 gatttatagc aagaatgaac tgcaggcaat cggtgaatgg gcagtaaaaa atgatatttt
     6781 gatagttgct gatgatattt atggccgttt agtttataat ggcaatgagt ttactccaat
     6841 tgcaacgatt tcagaagcaa tcaaaaatca gaccatcatc atcaacggcg tgtctaaaac
     6901 atatgcgatg acaggctggc gcattggtta tgcggtggga aatcctgtga tcatcaatgg
     6961 aatgatcgct gttgcttccc aatcaactag caatccgaca gcagtcagtc aatatgcagc
     7021 tgttgaagca ttgaaaggtg agcaagatac agtagaagaa atgcggaacg cctttgaaga
     7081 acgcctgaat acgttatatc cgcttgtggc agaactgccg ggtgtttctc ttgaaaagcc
     7141 gcaaggagct ttctatcttt ttcctaatgt aaaagaaacg ctacgcatgt gtaagtatga
     7201 aaatgtcaca caatgggtag aagatctttt agaagaaaca ggggtagcgc ttgtgactgg
     7261 cgaaggcttt ggggcaccag aaaatgtccg catgagttat gccactgatc gcgctacgtt
     7321 agaagaagcg gtacgcagaa tcaagcaatt tattgagagt aaaagtcaaa attaatcctg
     7381 aagaaattca aggaatataa aaggagagtc atacgtggaa caaattcaaa tcatcgattc
     7441 gaaaaaccat gtgggagaaa cagtaacaat cggcgcttgg gtcgcaaata agcgatcaag
     7501 cggaaaaatc gcatttttac aattaagaga cggaacagcc tttttccaag gtgtagttgt
     7561 aaaaagcgaa gtgtcggaag aagttttcca aacagctaaa aatctacacc aagaaacatc
     7621 cgtgttagta actggagaaa tccgtgaaga cagtcgttca aaatttggtt atgaaatcgg
     7681 aattacaaat gtggaagtgg taagcgagag ccacgattat ccgatcacac caaaagaaca
     7741 cggaacagat ttcttgatgg atcatcgtca tttatggctg cgttcttcaa gacaacatgc
     7801 gattatgcag atcagaaatg aaatcattcg tgcaacgtat gaattcttta atcaacatca
     7861 ttttgtcaaa atcgatccgc cgatcttgac tggttctgca ccagaaggca ctacggatct
     7921 attcgaaaca aattactttg atcaaaaagc ttatttatct caaagtggcc aattatacat
     7981 ggaagctgct gctatggctt tcggaaaagt cttttcattc ggtccgactt tccgtgctga
     8041 aaaatcaaaa acacgacgtc atttgatcga attctggatg atcgaaccag aaatggcttt
     8101 cactcatcaa gaagaaagtt tagaagtaca ggaacaatat gtagcattct tagtacaaaa
     8161 tgttttagat cattgcgaat atgcattaga tgtactagga cgagacaaag aagtcttaaa
     8221 aacttataca aaattgccat tccctcgtat tacttacgat gatgcaatcg aattactgaa
     8281 gaaaaatgga tttgatgaca tcgaatgggg cgaagacttt ggttcacctc atgaaacgtt
     8341 cattgcgaat tcattcgaac agcctgtctt tatcctaaac tatccaaaag ccatcaagcc
     8401 attctacatg aaaccacatc caacaagaga agacgtggta atttgtgcag atatgatcgc
     8461 accagaaggt tacggtgaaa ttattggcgg aagcgaacgg gcaacagact atgatttctt
     8521 gctagaacaa atccgtaatc acggtttgga tgaaaaagaa tattcatggt atcttgatct
     8581 acgtaaatac ggttctgttc cgcactctgg ttttggtcta ggccttgaac gaacagtcac
     8641 ttggattgct ggtatcgacc atgtacgtga agctattcca ttcccacgtt tgttgaaccg
     8701 aatttatcca taagaggtga tgaaaaagct gttctgcatc aagtaattag aacagccaag
     8761 caaaaacagc tgttcatgtt tttgaattgg cgggacttat taccgcagat gtaagctttt
     8821 gaataccgtt tagtggagag gttgtgaaaa agctgtttag tttcgagtat taagaaaaat
     8881 tttgtggaaa tggctttcca catttttgca taaatttggc ttaataccga gaaactggct
     8941 tttgaacacc gtttaaggaa gaggttgtga aatcagtgcc ttgacctgag tattagagaa
     9001 acaaaacgga aaaatagctt ctcatatttt accgtttttt tagctaatat cgagggtcag
     9061 ctgattgaac accgtttata tcaagaggtt gtgcgcctgc cgttcagctc cgagtcacaa
     9121 ggagtaattt caaaaaacag tttttcatgt ttgatgacta ttgtgacttg tgaccgagga
     9181 gttggccgga gagcaacgtt tatttaaaaa aaagaactgc gaactctcgc agttcttttt
     9241 ttaaaatacg ggataaagga agtttccagc agacaagaga agaaagcaaa agaaattgct
     9301 atttgattca caaggttcta taacgaaatc gcaatcaatc aaacatatac aaagaaggtt
     9361 attcaaatgg aaatctgatt tgatgatgct tctgctgttg aaataaagca gcatctagta
     9421 cctgaaaaca aactaatagt aacattcgaa gatggagtag gtccgtattt tcagcatgca
     9481 atgatccata tgtaagttta attcatcctt gaaatcatcg gaccagataa agttatgacc
     9541 aatctatccc aagcaatcta gaagagatat tagtaaaaga acatttactg gaagtcttag
     9601 atgagcctat aaatatatgt tctgatggcg tcatcagtgg tctgattgac ggaagcttag
     9661 gtgtgatcga tttctctgga ccaaacaacg aaggaatcaa ggggaatccg gcacgttaag
     9721 aaaaaaagta taaaaaacta gacacttgat gagcgttcat tcaattgatt gaagggacta
     9781 ggctggtgtc attttttata catatatttt ctctttcgtc ttgatagggc ttatgggata
     9841 atataaggaa gaaaatcatc gttttattca aaaaggagtt tttgacaaat gaaaaaacgt
     9901 atattattta tcggtgacag cattacagac gcaggaagag accgagcaga agcaactgat
     9961 ctaggtaaag gttatccact tttgattgcc ggaaaactaa tctcccaata tccaacgatg
    10021 aaatttgaat gcatgaaccg tgggatagga ggagacaaaa ttgcagatct gcaagtacgc
    10081 tggcaagaag attgtttagc tttacaacct gactatgtat cgattttgat cggaatcaat
    10141 gatacctggc ataatactag cgatcaggct atattcggaa ctgagaaatc tgcgcagcaa
    10201 tttgaatccg tttatcgaaa attactaaat gaacttcaaa cagcggaaat ctgcaacatc
    10261 atcttgatgg agccgtttgt acttcctata accgacgacc gtcatggctg gcgtaaagac
    10321 ttagacccta aaatccaaat tgttcgtaaa cttgctaagg aatatggcgc attgctggtt
    10381 cctttagatg gcatattcaa tgctttaggg attgcttatg gtttttcgaa atatacaaga
    10441 gaagatgggg tccacccaac gattggcgga catgagatca ttgcacaaag ctggatagat
    10501 gcaattgccg cagtcgattt ttttagtgga gataaaaatg agcgaaagaa aagtgagaaa
    10561 tgatggaaat acggtgggca gtaaaagaag atttacctca aatcaatcag ctgattactg
    10621 atcatccaga atcattcgta aaagcaaaaa cggcagctga cctaaatgat aagaataaac
    10681 tattgctcgt tgctgtaaca aaagaaaaac ggattatcgg atttgcgcaa gcggacgtgc
    10741 aacagtcaga agaacgggtg gatcagcgac catcaggaaa actaatccaa cacacattag
    10801 taacaaaaga aaatacggaa gaaatccaaa aaaaatttgc agaatacttg atgctggaag
    10861 ctaaaaaaag aagaataaaa tcaatttttg cccagtttta atcaaaaaca gtaatagaag
    10921 gagaaataca atgagttgtt taggaaatgt catctggttt atattcggcg gactaatcgg
    10981 tggtcttagc tggttagcag cggggatact ttggtgtatc acgatcatag gtatcccaat
    11041 cggtatgcaa tgttttaaga tcgcctccct ttcttttgcg ccttttggca aagaagtaat
    11101 ttatcaccag tctggcatgt cattgatcgt taatatcatc tggctgatcg tttcaggcct
    11161 accaattgct ctcgcacatg tcgtcagcgg catccttcta tgtatcacga tcatagggat
    11221 accttttgcc aagcaatctt tcaaacttgc tcgattggcg ttgatgccat tcggtgcaga
    11281 aattgtataa aaagagaata ataaaggtta gaaaacgcat agagtcaggt gggatacatg
    11341 tatttcacct gactctatgt gttttcctgt ataagttctc ccatgtgact tttacgtctt
    11401 ttatttatat gggattactg tttatggaaa gttgaaataa ttttcattaa agaactcttt
    11461 ctatattttt gaaagcgtag tggagcttcg aatatctggg aaggacattt tgcagggatt
    11521 gaaaaaagat attgtcctat cgaaaaatta atgaatttag acaaattgcc agcaacaggc
    11581 ttcaaactta gttgctatcc tgtcaagatc aagaaggcaa gtgcgggttg gataagagca
    11641 ggggcaatga tcgaagagaa aaagaaagaa taagccaaaa catctgtatg gaagaaattt
    11701 tccgatgcag atgtttttca ttttttcttt cggatacctt gacatatgaa taaccattca
    11761 tttataatta gttatgaaga gatgttcata tgttgaggcg aggaggtcat taaaatgaaa
    11821 agttacagat tagaaggttt agattgtgcg aactgtgcaa tgaaaatcga aaaaggagtt
    11881 cagaagatca atggagtcaa ggaagcaacg gtaaacttca cttctggaaa actaacgatt
    11941 gacgcagagg aagatcattt ggctacgatt gaacaagaaa caaaaaaagt agtgaaggaa
    12001 ttagaaccag atgtcaaagt aacagaaata gataaggaaa aagtatctga acatggaaat
    12061 gaaaaagaga gaaatacgct gttccggatt ttattttccc ttgcaggtat cgctttattg
    12121 ctattatttg attttaatga accaattcgc ttgatagggt atttattgat ttatctgctg
    12181 ataggatatg atgtagtgaa gaaggcagtg atgaatatcg tcaaaggaaa aatctttgat
    12241 gagaattttc ttatgtctgt tgctacgatt ggcgctatgt tgatcggtga atatccagaa
    12301 gccgtagcag tgatgctatt ttatcaaatc ggcgagtatt tccaaggatt ggcagtcagt
    12361 cattcaagaa aatcgattcg cgaattgatg gcgatccgtc cagaaacagc tcacgtgcag
    12421 acgacggaag gattgatgac cgtgaaccct gaagacgtgc agatcggtca gtttgtactt
    12481 gtgaagcctg gtgaacgtgt accgttagat ggaacgatca tcgaaggaga atcattagtc
    12541 gatacgtcag cacttacagg agaatcagtc cctaaatctg tatatgttgg tgaaacagta
    12601 ttaagcggat ttatcaataa aaataaacca tttttagttc aagtagaaaa atcttatgaa
    12661 aattctacta tcagcaaatt attagaatta gtagaaaatg ccagcagtaa aaaagcacca
    12721 gctgaaaatt tcattactaa attcgcgcgc tattacacac cagtcgttgt aggattggcc
    12781 gttttattag ctgttttacc tccacttgtt gtttctggag cggcgttttc tgaatggatc
    12841 tatcgagcat tgacattttt agtgatctca tgtccatgtg cattagtgat ttccgtgcca
    12901 cttagtttct ttggcggtat cggaggcgca agtaaaatcg gtgtattagt aaaaggttca
    12961 aattacttgg agttgcttgc gcaaaccgag acagtggtat tcgataaaac cggcacatta
    13021 acgaaaggtg acttttcgat ccagacgatc gatacaaaaa tcgatccaaa gaaattcatg
    13081 caatatattg cgagtgcaga acagttttct acacatccga ttgctcaatc tgttttagaa
    13141 ggctacgcag gtccgctttt accaacaact aatatccagg aatttgcagg tgaagggatc
    13201 ttagctgaag ttgatggcaa acaagtatta gcaggtaatc acaaattgat ggaaagattt
    13261 gaaatctctt ttcctttaag tcaagaaatc ggtacattgc tttatctagc gatcgatcaa
    13321 agttacagtg gttatcttgt tattgcagat accttgaaag aagatgccgt agacgcattg
    13381 gttcaattaa aacaggctgg tgtgaagaac acagtcatgt tgacgggcga ctcgaaaaaa
    13441 attgctgatc atatcgggaa gcaagtaggc gtggacaaga tatatagcga attgcttcct
    13501 gaagataaag tgcagcggtt agaggaaatc ttacaaagaa acaataaaaa gaccgcattt
    13561 gtcggagatg gaatcaacga tgcaccggtg ctagcaagag cagatgtagg aatcgcaatg
    13621 ggtggattgg gaagcgatgc tgcaattgaa gcagcagatg tagtcatcat gaatgatcaa
    13681 ccatcgaaga ttgcagaagc aatccattta gcaaagaaaa cattgaaaat cgtcaaacaa
    13741 aacattgtct ttgctattgg gataaaaatt ttggtacttg ccttaggtgc ttttggtttt
    13801 gcatcaatgg gagatgcagt atttgcagat gttggggtga cagtattagc tgttttgaat
    13861 gccatgcgaa gcttgcatgt aaaaaaagag gacgaatgaa cgtcctcttt tttttatatc
    13921 cttttcttaa tgaaaaatgt aaagaaaata gataggatta taaaataact
//
LOCUS       DAFLWC010000077        13644 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.078, whole genome shotgun sequence.
ACCESSION   DAFLWC010000077 DAFLWC010000000
VERSION     DAFLWC010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13644
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.078"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(261..953)
                     /locus_tag="L1V17_002216"
     CDS             complement(261..953)
                     /locus_tag="L1V17_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBN1236963.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            complement(1390..1959)
                     /locus_tag="L1V17_002217"
     CDS             complement(1390..1959)
                     /locus_tag="L1V17_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBN1236964.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(2033..2356)
                     /locus_tag="L1V17_002218"
     CDS             complement(2033..2356)
                     /locus_tag="L1V17_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236965.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2510..3322)
                     /locus_tag="L1V17_002219"
     CDS             complement(2510..3322)
                     /locus_tag="L1V17_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236966.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3676..4524
                     /locus_tag="L1V17_002220"
     CDS             3676..4524
                     /locus_tag="L1V17_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBN1236967.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4669..5610
                     /locus_tag="L1V17_002221"
     CDS             4669..5610
                     /locus_tag="L1V17_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HBN1236968.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5600..7771
                     /locus_tag="L1V17_002222"
                     /pseudo
     CDS             5600..7771
                     /locus_tag="L1V17_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(7883..10054)
                     /gene="copB"
                     /locus_tag="L1V17_002223"
     CDS             complement(7883..10054)
                     /gene="copB"
                     /locus_tag="L1V17_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HBN1236969.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIR"
     gene            complement(10074..12260)
                     /locus_tag="L1V17_002224"
     CDS             complement(10074..12260)
                     /locus_tag="L1V17_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBN1236970.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEVKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLCLNRHMKK"
     gene            complement(12260..12469)
                     /gene="copZ"
                     /locus_tag="L1V17_002225"
     CDS             complement(12260..12469)
                     /gene="copZ"
                     /locus_tag="L1V17_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HBN1236971.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(12482..12922)
                     /locus_tag="L1V17_002226"
     CDS             complement(12482..12922)
                     /locus_tag="L1V17_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HBN1236972.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYYPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(12996..13535)
                     /locus_tag="L1V17_002227"
     CDS             complement(12996..13535)
                     /locus_tag="L1V17_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBN1236973.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQLFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
BASE COUNT         3841 a         2846 c         2419 g         4538 t
ORIGIN      
        1 tcaaagtttt attatacttg tcaatttgtg tacatcctaa aatataagct atttgtttac
       61 ttctgtagaa tatatacttt gttgttagat aagttgcaca tgtttataga atctaaataa
      121 taaattttta tgtaccgccc ctcaaagtga actgaacccc aaaagttgaa ctatttaatg
      181 gactgtttcc gatattctac tggagatagt ccattaaata gttcaacttt tggggttcag
      241 ttcaaagagg gggggatttt ttatcgttgt ggaatattta aataccaacg cttgtcatga
      301 aaatcttgtg ctccaccctt agtatttcct tctggatcgt ttgtcgcacg catcatgacg
      361 tatactttct tattagggaa atcacgcata ttgaaagata catgatagcc aacatttcct
      421 aaagtattat aagcttgatt tacgtctggt ctataaatcc catcagctct tactctagct
      481 agttcttttc cagtattgta gtccataatg aaaatatact cgtatttata attagcaatg
      541 tgccatccag ctacatgcaa gtttgcgttt tcgatttctc cgaactgatc aatgtgggcg
      601 taatttgttc catctgtcag cgtagaattt gcagcacctg ctcgagttgg atcaattact
      661 ggtttatcct ccgaagtagt tggattatca tccgtaaaac catgagccaa atcataggct
      721 agtttttctt tacttacacc catttcagaa agataaccgt aaggatctgt atgatcgccc
      781 caaatatttt gtgttaccca taaatgcgat ttgattcctg gttggttata aggagtgtct
      841 aatgttaatg gaataccata tttcattgct gaatctcttg ccaattcaac gtatacttta
      901 tagttctttt caaaagtttc tttatcatgt gtatgttgta actcgatttg cacaggactt
      961 ttggctcacg aggttgtcct actctacatc ttgctgatag atatgctgaa aggaaaacac
     1021 caacattatg ttttgctttt tcagctagaa cgagacaagc aggaatacct ttagaagata
     1081 tcaaaggttt tttaggtcat aaagatgttt ccactacaca agtctatgcc catatttctc
     1141 ccgaagtgaa aaaaagatca atgaatcaac tagaaaacta tatagaagag caaataaaaa
     1201 agcactcaaa ttgagtgctt ttttaagctc actatcacta aaactatcac taattttatt
     1261 tataagcgaa catgtttcta tcactgattt tttaaatcta gcgaaaaacc cttatcttaa
     1321 aggcgttcgt tcaattcttt ggcaaggtct tcaaagcctg gcttgcctag aagtgcgaac
     1381 atggttttct tatagctcat gtagaaaaat tttcttgatg atgattttat ccatcaattg
     1441 agattgactg ttttgctctc ctatgatttc agctatgatt gtccgatttt gcggttttct
     1501 tcttaactgg tagttgattt tcccagtttc catcaactcg ctaagcatat ccacgactcc
     1561 gccaaatccg gtctttttcg taataaaacc tagtgctacc attcgttcat ctagattttt
     1621 tgctgtaatc gtcacaccag taatgagcga gtgctgtaat gtttgggcca gctcttccat
     1681 cccttcagca ttggatacga cggaagctgt tttgttaata ggttcttcgt ttatttcttt
     1741 tggttctttc ctctccactt tcactgtttg acgaaggaca tctagttctt gcaagagcgt
     1801 ttcgtattgt tcttgggtca gcatcacgcc agctactttt tcacgattaa atatatatac
     1861 gccagttccc gcgtctcgcg cttgagcaaa tacatccatc ggcgatcgtt tcacttctgt
     1921 gatcgaagat gtgggaactt ctaatttctt taattccaat ggatttcctc ctttactaat
     1981 cgctttttat tatagcacag actgacttgt tttgatcttt tttccaaagg ttttatcggt
     2041 ttttgcctaa ccagtaattg atatcggtaa gaagtctttc gataccaaat gaaggatggt
     2101 acagatacgt tttttgatct tcgttatggt ctagtggaaa aaaatgatcg atgatcacta
     2161 gatctgcata ccgaggcggc ttatttcgag tacatacatg tatagagatc cgttttcgat
     2221 gtcttagcgt tttgttcagt accccagcaa gtcttcttgc ttcttggtgt tcatagcgaa
     2281 aaaaaaagac gattttcact tcaggagggt ggacatctaa ataccctcgt tcctggagtg
     2341 ttttcagtaa aagcatcccc cactctactg cggggtgtgc aagtgcttgt tggatcgcta
     2401 gccgaaattg atatagttta tctttggaat tgggaaattt ttctaatgtt tcctgataat
     2461 aacgaacttc ttctatcagc cggtcatgga taccaattac gtaacgaagt cattcttggt
     2521 aaagtacttt tgtcagcttt gatttgcttt cgctctcaaa ttcgctattc agccaaaaca
     2581 gcgaatcaag cttttcagtc acaatcgtca atttccgata gtcttgtgtc tcttctatcc
     2641 gtttccaccg cttttcagta atctggttac agctcaagcg caaaattgct agataatttt
     2701 tttcttttat tggcaaaatc tgctcctctc taaatagcaa ttcaggaaac aattcaaaga
     2761 atagtgttcg actgtctcct aaaatctcga tttctgccgg atcctttctt tgcttcaata
     2821 attggatgaa catctcagaa aaggactgct ctccatcatc tgcaaaaaaa tgcggaaaat
     2881 ctttcaaaaa gcaaaacagc agatatctta cttttctttc tgaaccaaag atctgtgctt
     2941 ttttataaga aaaagaaagg tggtactcgc caaaccactt tctcaatcgc tcttgcgtag
     3001 aacgatcgta cttctgctcg taaggttcat tcaatagcag atttttcagt aaacaaaacg
     3061 ggggtgattg gatcagaaaa acaaacaaga gataaggttc gctatatcct tgatcataaa
     3121 ctaactgaac ggttttctta tgaagaatca gctgaatggg acagtcgctt tccgccaaac
     3181 gtttcagatg ccgatccact gttttaacat cgattttcag ttcttcagct aaatcagctt
     3241 ttcgccagat caaatctttc attagattga ttagtgaaaa taaattctgt gcattttttg
     3301 ataatagttt ttgccatctc atcgatcatt tctcacctga tttctaaaca tattgtttga
     3361 tcaaaatggg ttcactccta aaaagataaa aaactccctt tctatttatt taaatacgca
     3421 aatcttcctc attatttttt attttactca atttaatcgt attctcattt caaaacgaat
     3481 gtactttaaa aaaacataat aagatcactt tgcttgtagg atgtattccc ttccattaca
     3541 atgaaataaa tagcgatttt atgagaaggt gatgtgaaaa tggaagaaaa aatagaagaa
     3601 tccaaacaaa aaatcgatca gttgatataa gaattagaaa aagcggtcat cggcaaacgt
     3661 tcaactatcc aattgatgat cgtggcccta ttagcaggtg gtcatgtctt attcgaagat
     3721 attcccggtg taggtaaaac gttactggtc aaagcactag caaaagctgt acagggaacc
     3781 ttcagcagag tccaatgtac tcctgatctg ctgcctagtg atattcttgg tttttccgta
     3841 tacaattcac aatcaaaaga gtttgaattt cgtccgggac cgatctttac cacgatcttg
     3901 ttagcagatg agatcaatcg tacgactcct cgtactcagt cagcactttt agaagcaatg
     3961 gccgagaatc atgcaacgat cgacaacaat acataccctc tagacaatca tttttttgtc
     4021 ttagctacgc aaaatccaat cgagtacgaa ggaacatatc ctttgccgga agcacagctc
     4081 gatcgttttt tattccgact acaaatcggt tatccttctt ttgatgacga acttttgcta
     4141 cttttggata aattcgaaaa agtgttggat aacttaaatg aagtattgaa cagttatgaa
     4201 atagaagaaa taaaaacaaa tgtggcgaat gtctttgtca gtcccgaagt ggcatcttat
     4261 gccttgcagt tagtgtcagc aacaagaagt catgctgcca tccagcttgg catcagtcca
     4321 cgaggaagcc tttcctttat tcaggcagca aaagcttatg ctttaatcca tgggagaaat
     4381 tacgtcacgc ccaaagattt gcaggattta gttccttacg tgttttccca tcgcctgatt
     4441 ttttacgatc gttcattgaa ggaagacgaa aagaaacaaa tcattcatac tcttgttgca
     4501 caaattccta ttcctgtgag gtagattgag gtagacaatg gaaaaaatca aagattattt
     4561 cattaatttt gtgttatttc tggtatattt catcattgtg ctttttgctc ttgtattcaa
     4621 caattcttta ggctggttct tgttggcctt ttttactctt tatgtatcat ggagcttgat
     4681 ttcattaagc agctttctaa agaaactttc ggttacttgt acattgcagc cactcgttta
     4741 tcgcaaaaaa agtatgcagg ttattttttc catagcaaaa aagagaactt tttctttacc
     4801 tctccctcgt ttacaaatcg gcttcccagc aatctttgca gaaaaaaaca agagattttg
     4861 attcttacaa ataaaccgca agaagtccaa ttgctttggc agccaaaaga aagaggatgc
     4921 catgaaacat taactgtcat ttttacagcc tatgatagtc taggactttt cagaaaaagt
     4981 gcaaaaagag agatctcttt tcctgtgact gttctgcctg ctttttgtaa gattcaagca
     5041 gaaaaattac agagagttct ggaaaaaaaa cagcagctga acgcgtacca aagaggtctt
     5101 gattttcggg aacatcgcgc ttatcgtcca ggtgattctt tcaaccgaat cgattggaaa
     5161 ttgtctgctc atactcaaga gtggttatac cgtgaatacg attatcaaga agaagaatgt
     5221 tctcctcttt tttgcttttg gggttcgccc agtccaaaat ttgaacctct gctagacttg
     5281 tatttttctt tatggcattt gagaaaagaa aagcagccgg aacttctgat attaggcaac
     5341 cgcgcctttc atggcaaaga ccccggtcat acctattttg cttctttgga agctggcgat
     5401 gagaaagctt ttttcgcaca cttgaaaaaa tatgcaaaaa aacaaatcgt cctctttgtt
     5461 cctgagaatt ctcctgaagt ctcagaagct attgaaacat tgtcaaaaga tcgaacggtt
     5521 tatcttgttt atttcgtaga aaaacaactc atggtccaag aaaaagacaa gatatgttca
     5581 ttgccaggag gtgaatggat tgacgattaa acgggaaaaa tggctgcgtg gcgtttactc
     5641 ctttgtgata ctaagtgtag gtgctccgat atttgtagta gctaatcaat tgcaaaacag
     5701 ctaccttctt atcctaacta ttggtgtcct atgccttatt gtctgctgta ttcctaaaaa
     5761 atgggtacgt ttgctgcttt ctttgccagt aatgataggt tgtttgtttt tatattttcc
     5821 ttcgaagaca ttttccatat tatggatctt acagtttttt tcgtcagtca cagaggaatt
     5881 cttccatcta tcccaaggta aactttatta tttgccagaa aagacagctt tttttctcat
     5941 aatgttgctg atctatttat ttattacatt gaccgtggat tacgactatt ggtacgcacc
     6001 ctttctttct ttgatggctt acttcatgat gcttaccgtt tttcggaaaa aagatttact
     6061 gtacgaaatg attgcggtag taactgtttt gttcgtgtat ctggcagcaa ggcaattttt
     6121 ctccatccgg ttgttgtcgg gaaacactcg attccagtca ttgactacag ttctgcttat
     6181 ttgtttctta acttttagcg ctatcttgcc tttatatctt ccgaaagtac accaatctct
     6241 cgaggaaacg agtgaaccga tccgagaata tcttaatgat gaagggcttt atgacacact
     6301 ccatgagtat caattaaccg gaagtgcaag aacaggcttc agtgagaatg atgaacagct
     6361 tggtggacct ttatatgata atggcgaagt tgtttttaca gcgaaccaaa aaggaaatgg
     6421 ctattggaag atcgaaaata aaaatcatta caccggttct ggatggatag aagatcagga
     6481 cgcacccatc caaccaatcc aagaattccc tgttgacatc acgagctacc aaaccgttat
     6541 agaagacaaa gaaaacatta cattgaccct aaaaaaacaa gttttcttac cttatcctta
     6601 tggaaatact accttgactg atttttcatt agctagtgga caaacgcttt actatttgcc
     6661 tgaaagccag cgattcattc ctgtcccgaa tgaatcgaca cgttctgcaa ctttacaaac
     6721 agaaaggtta gtttttacga gagaagaatt aaaaagcagt cagttaaaag ctgatgattt
     6781 agaaaatcag cagacaaatc ttcaattgcc aaaaagtttg cctaaacgta ttgaggactt
     6841 ggcggtcgaa ttgaccaaaa atgaagcaac tttaattcgt aaagtcgaag ctgtctaaca
     6901 gtatttaaaa acaagcggaa atttccgcta ttccaaaacg gataccgggc atactccaaa
     6961 agaacacgat tatgtggatt atttcctctt tgattcaaaa gtcggctatt gtgacaactt
     7021 ttcaacttct atggtcgtcc ttcttcgaac acttggtatc ccagctcgct ggacaaaagg
     7081 ttttacaaat gggctcagaa caggcacaga taatcaaggg aatgaggaat acagcattct
     7141 caatagtcat gctcattctt ggccagaggt atactttcct ggatttggct ggcttccatt
     7201 tgaaccaacc ccttcatttg ccaatccaat gggttcacaa ccagttgctg aaacaaccga
     7261 aaccgtccag cctgctatcg aacaaccaaa tgaaagcgaa aatatggcag aaactatttc
     7321 cagtgagaga tctgaggtca ttccatcaga agaaacaaca ctcacaccag cttataaaat
     7381 cgtcttattc agccttggag tgtgtttatc cgtcttgttg ttctttctat tgttattcag
     7441 aaaatctctg cgctggacaa gttatcttat ctatcttcat ttttttgctt ctactaatac
     7501 gattgcatat caaaaacttc ttaacccttt ggaaacattg gtaccgcgca aacccgcaga
     7561 atctttgcag gaatatagcc tgcgaataga acaagaattc aagctagatc tgcgtttcat
     7621 tcgattaact actcaatatg aagcagaaat atatggacga caagcagatc cggtaaaatt
     7681 cgataaaaaa acctatttag aaataacgca tataataaga aaaatggtat acaaaaaaat
     7741 tctgacaaaa gggagccgct tcaaaaaata agataaaatt tctggagaat ctacttctgg
     7801 aatgccgaga accagctgat tgagtatcga ttactcgaaa aaaaggttgt gacacgtttt
     7861 ttgtcacaac cttttttcat tattatctga ttttcaatgt caaagcattt agagctacaa
     7921 ctaccgtact taacgacatc aagacagcac caactgctgg acttaatatg ataccaattg
     7981 gcgcaagaat tccggctgct agcggaattg caagaatatt gtaacctgcc ccccaccaga
     8041 ggttctggat cattttcttt cgcgtttgct tggctagatc aagaaaatgc aaaatatctt
     8101 ttggatcgct gtttgtcaat acgacatccg cagaatcgat tgcgatatct gtccctgcac
     8161 cgattgccat cccgattgaa gcacgggcta aacttggcgc atcattgatc ccatcaccca
     8221 ccatgattac ttttttccct tggtcaaggt atttctggac aacagcttct ttatcatctg
     8281 gtaataaacc gccataatat tcttcgatcc ctaaataatc tgctactgct tgggcagcgt
     8341 ttttattgtc accagtaagc atgacaggag tgatttttct ttctttcaat gttcggataa
     8401 attcttttgc ttctgttttt actacgtcac ctaaagcaac gattgcagct agatgatttt
     8461 ctaaaatcag gaagctgatg gtatttcctt gttcttggta aggtttcaat aatgcttgtt
     8521 ctacgtttaa tccgagacgc tcaacttctt tttcattaac tattttcact tgttgttttt
     8581 tgactgttgc ctctagcccg actcctgaaa gattttttag attttcagct tgataaggct
     8641 tgatttcatg ttctttcaaa taattcataa tgccaacagc caatggatga ttggcattcg
     8701 cttccaaggc tcctagatat tgaaggattt catttttatt gaacgcatca tcaagtactt
     8761 cgacacccgt tacagtaaat tttccttctg ttagtgttcc tgttttgtcc agcatgatca
     8821 catctagatc attggcttgc tccagtgcat tgcggttttt caaaagtaat ccgtttttag
     8881 ctgctattga tgtggaacga gcaacaacta atgggatagc taaacctaga gcatgaggac
     8941 aggcgatgat aaagactgtt accatacgtt ctaatgcatt aggaagatct gtcaagaaca
     9001 accaggcgat gaatgccagg atacccacaa ttaatgcgac ataaaacagc cattttgcca
     9061 ctttgtcaga taatgactct agcttggatt tttctccttg tgcttttcgc accatttcca
     9121 taaccttcgc tagataacca ttttcaccag ttccagttac ttcgatttcg atcgttccat
     9181 ccccattgat agaaccgcca atcactttgt cattggcttg ttttttgatt cctcttgatt
     9241 cgccagtcac agctgattcg tcaacaattg tttcaccttt caagattaca ccatctgttg
     9301 gcattttatc accagaccgg acgatcaaac gatcaccttc gtttacttct ttcaatgaaa
     9361 ctgtctcttc ttttccatct ttcgtcaagc gtttcactga ttctggcagt aattctgcta
     9421 gtttttgtaa agcattgctg gcattcgaca cagcattcat ttcaatccag tgacctagta
     9481 gcataataac gatcaaagta gccaattccc agaagaaatc catgacgtgt gtatgtggat
     9541 tgagcagatt tgcgataaac gaatagacac tataaatata tgcaactgta atccccatcg
     9601 cgatcagtgt catcatagca ggactttttt gtttcaattc catcttagct ccacttaaaa
     9661 atggctgacc gccatagata aatagtatag ttgctaagat caatacgagc caatcagaac
     9721 caggaaacgt tacttgaaat ggaaattcca ttcccatcat tggtgaaaaa agaatgattg
     9781 ggatagctag gataagcgat agccaaaatt tttgtttgaa attccccatg tgcatggaat
     9841 gatccatgcc gccgtgttcg tgatccatgt gcatcgaatg gtccatttgt ttgctgtttg
     9901 ctatatctcc atggttatgt cccatgtgca tggaatgatc catctgacta tggtcatgtt
     9961 tcatctccat ctgtttttca tgagattctg tactttcttt gtttactact tcttttttat
    10021 gctcatgttt tttctccata tcgttcccat tcatttttac tccatccctt ctcttacttt
    10081 ttcatgtgtc gatttaagca cagggagttc aacaatacac tgacggaact aaacgccatc
    10141 gctcctcctg caatgattgg attcaaaaag cctagtgcgg caaaaggaat accaatcgta
    10201 ttatagacaa aagcccagaa aagattttgt ttgatttttc tcaatgtcaa cctagacaac
    10261 tcgattgttt gtgcaatgga tgccaaactg ctattcatca gcgtcacatc ggctgtttcc
    10321 atcgcaatgt ccgttccact tcccattgcc ataccgacat cagctaatgc taaggccggt
    10381 gcatcattga ttccatcgcc tgccataccg acttttttgc catctttctg aagtttttct
    10441 acgtaggctg ctttatcctc tggaagtact tcagcaaaga tatgctttgg atcaatacca
    10501 acttgtttac caatcgtttc ggctgccagt ttgttgtctc ctgtcagcat aaaaacatct
    10561 aatcctttat tctggagctg cttgattgct tgtttgactt ctagtttgat ttgatcagcc
    10621 acggcaatca acccgatcac ttgcttttca tcagctaaaa acatgactgt ttttccctgc
    10681 tgttctaatt ctaacgcgtg ttcttggtat tcatcaaatg ataggttcaa ttcaattaat
    10741 cgtttacgtg tacccgcaaa atagcgtact ccgttaatcg taccgctgat tccagcacct
    10801 gggtgggctg taaaatcaat catatcgtat gttgctgctt cttgcagttt tccgtattcc
    10861 acgattgctt tacctagtgg atgttcagaa gcttgttcta aagtataaaa aatagatagg
    10921 acttctttag aaccgactag atctgtaact ttgggctttc cttctgtaat cgttccagtt
    10981 ttatccaaaa caatgctgtc taagtgagca gctgcttcta atgcttctcc gcctttaatt
    11041 aaaattccat ttcgtgcacc aacacccgtt cctaccataa tagctgttgg agtcgctaaa
    11101 cctaatgcac atggacacgc aatgactaat acagagacac tatggatcaa tgcgagttgc
    11161 caatcaccag tgatcaaacc tgtagctatg agcgtgataa acgcgatgac taatacgatc
    11221 ggaacaaaaa tccctgagat ccgatctgcg attttttgga ttggggcttt gctcccttga
    11281 gcatcttcca ccatttgaat gatttgcgct aatactgtct gcttgccgac ttgtgtaact
    11341 tccatgtgaa gtagaccatt cgtattgatt gtcccgccaa agagcgtgtc atccggattc
    11401 ttttctacag gaagattttc accagtaagc atactttcat ctatcgcact gcttcctgaa
    11461 ataattcgac catctgctgg aatctgctca ccaggacgga tgactagttg atcaccaacg
    11521 actacttctt caatcgctaa cgtttcttct ttcccgtttc ttatcacttg ggcggttttt
    11581 gtttgaagag acatcaattg tttgattgca ttacctgttt tcgtttttgc tgtatgttcc
    11641 aaatatttgc cgagcaaaat cagcgtgatg atcatactgc tgctttcaaa ataaagatct
    11701 tgggggtgtc cacggaaaaa tccgttgtaa atgctcaatg caaaggcagc cgatgttcca
    11761 attgctacca atacatccat atttggtgct ttcgtcttga ttgcatggta cgcaccttta
    11821 taaaaacgag caccgacata aaattggaca ggagcagaca gcactaactg gacgattgga
    11881 aaatgaaaaa agtgaacaat cgccgcatgg cttcctaaca tcatagcaat cattgacaac
    11941 atcaacggca aagtcaaaac cgtactcaat ataagatcga atagcatttt tttcaaatac
    12001 gcttgctttt cttctgcaat tttttgtttg tgggcttcat cgtacaaaat tgcaccatag
    12061 ccgatgtttt ctacgctttg gattaatttt tcagtggtcg tcccttcata tttgacactt
    12121 gctttttcag tggccaagtt gactgtggca ttgaccacac caggttgtcc gttcagctct
    12181 ttttcgatcc tagcagaaca atttgcacaa gtcatacctg taatgacgaa cgtatccatt
    12241 ttggtttctg ctgttgccat caaatcacct ctgctttata acccaatcca ttgattgctt
    12301 gacaaatctt ttcggattga acttttgttt catcaaactt gaccgtaccg tttgcttttt
    12361 tcaaatttac tttcactttt tgcacgccgt caagtgcgct tactgtttct tctactcttg
    12421 ctgcacaatg attgcagctc ataccttcga ttgaaaattg ttgtttcatt ttttcttcct
    12481 cctattgatg ttgtttacat tcacattgac ctgggataca gttacattcg atcgtatcta
    12541 ctggttgctt ttgttccagt tgtttcaaaa tctcattgat atcttcttga gtcaaagtgg
    12601 cttcttctac tagatccgca atcgtctctc caatcctttt tgcacagata tgggaaaaaa
    12661 gattttccgt cgcactgcga actgtttcca tctccgagac agctggataa taaatgaatt
    12721 tttttccttc ttgttctgtc cagatcactt ctttttttac caaacgaccc agcaaagttt
    12781 tgatcgttgc tggtttccaa tccatcgaat cagctaagat ctgcgtgatt tcttgggctg
    12841 tcgtctgtcc aagtgtccaa ataacacgca tgatctccca ctctgaatca ctgatcttta
    12901 ctggcgtttt gactttttcc atttatttca cacctttcgt ttacaaatgt aatcattatc
    12961 ttatgaatac agattacact tgtaaacaaa aactgtcaat tatttttgct ctctattttc
    13021 aatttagtta aaaattcttg tttctctcgt cttgttttaa ggatgatcag tttatttctt
    13081 gcattagcta cttggatcag ctgctgtatt ttcggttcat tgttttcttc aaaatgccag
    13141 ataaaagata aaaattctaa gtattccctg tttagtttct ccgaaaatga ttcaggcata
    13201 tctggccgag attttttgtt tatctttctt tttagagaac gccaaactac tcggtagatg
    13261 gcgagataac gcggcacttt aagccaaatg atcttatctg cttctttaat cctttcctct
    13321 aatgtagaag tataatttcc ttcaacgatc catgacggat tagataccat aaacaattgc
    13381 tgttcttgca aaaaccactt ttttgcctga atactgtagt ctgttgtatg ccataaaagg
    13441 tctagcggca gtagcggaaa gtcggtgatt tctttgatct tccttgcgag ggtcgatttt
    13501 cccgacccac tttgtccaat cacgatgatc ttcattcttc tccctcactt ctctttggaa
    13561 tttggttcga tcataccact tataacgccg caaaaaaaca agggactgtg acaaaagtcg
    13621 tgtcaaagtc ccttgtttcg aata
//
LOCUS       DAFLWC010000078        13404 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.079, whole genome shotgun sequence.
ACCESSION   DAFLWC010000078 DAFLWC010000000
VERSION     DAFLWC010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13404
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.079"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            79..1125
                     /locus_tag="L1V17_002228"
     CDS             79..1125
                     /locus_tag="L1V17_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HBN1236974.1"
                     /translation="MTKPNHIESSKKEAPKTEGQTKTFSTPQQIESTESFQSQPILSG
                     NEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIAQAILESASGQSQLAQAPNY
                     NLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYENYEESFEDYAKLLTKGISGN
                     KDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNELIKTYDLTNYDKEVKGPQMS
                     KTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIHAVKAGKVVKAEFHYSWGNY
                     VVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGSTGNSTGPHLHLEICKDSSLS
                     QSMLVDPKTLLFGD"
     gene            1474..2106
                     /locus_tag="L1V17_002229"
     CDS             1474..2106
                     /locus_tag="L1V17_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HBN1236975.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            2694..4133
                     /locus_tag="L1V17_002230"
     CDS             2694..4133
                     /locus_tag="L1V17_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1236976.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            4428..4646
                     /locus_tag="L1V17_002231"
                     /pseudo
     CDS             4428..4646
                     /locus_tag="L1V17_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251366.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            4895..5110
                     /locus_tag="L1V17_002232"
     CDS             4895..5110
                     /locus_tag="L1V17_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236977.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(5327..5583)
                     /locus_tag="L1V17_002233"
                     /pseudo
     CDS             complement(5327..5583)
                     /locus_tag="L1V17_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5770..6681)
                     /locus_tag="L1V17_002234"
     CDS             complement(5770..6681)
                     /locus_tag="L1V17_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBN1236978.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(6700..7704)
                     /locus_tag="L1V17_002235"
     CDS             complement(6700..7704)
                     /locus_tag="L1V17_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBN1236979.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(7701..9824)
                     /locus_tag="L1V17_002236"
     CDS             complement(7701..9824)
                     /locus_tag="L1V17_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBN1236980.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(9829..12276)
                     /locus_tag="L1V17_002237"
     CDS             complement(9829..12276)
                     /locus_tag="L1V17_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBN1236981.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(12263..12652)
                     /locus_tag="L1V17_002238"
     CDS             complement(12263..12652)
                     /locus_tag="L1V17_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBN1236982.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(12712..13215)
                     /locus_tag="L1V17_002239"
     CDS             complement(12712..13215)
                     /locus_tag="L1V17_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBN1236983.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(13228..13389)
                     /locus_tag="L1V17_002240"
     CDS             complement(13228..13389)
                     /locus_tag="L1V17_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1236984.1"
                     /translation="MAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGVKDVLL
                     SLFNRIVGA"
BASE COUNT         4099 a         2642 c         2454 g         4209 t
ORIGIN      
        1 tcaagtgaaa gtagtacgat ttcaagtacc gaatcttcaa caacttcaag tagtacaagt
       61 gaaataactt cttcgaaagt gacaaaacca aaccatatag aatcttcaaa aaaggaagcg
      121 ccaaaaacgg aaggacaaac aaaaactttt tcgacaccac agcaaataga atcaacagaa
      181 tctttccaat cacaaccaat actatctggt aatgaagaaa ttcattttga caaaaatgaa
      241 tctgtagaaa attttattat gaaaattggt gagtctgcga gaaaaattgg tcagaaatat
      301 gatttatatg cttctgttat gattgcacaa gcgatcttag aatctgccag tggtcaaagc
      361 cagttagctc aggcaccgaa ttacaattta tttgggataa aaggaactta taatggaaac
      421 tttgtcatta tggtaacaaa cgaagatttg ggtaatggaa cgctttatac gacccaatca
      481 aaatttagag tgtatgaaaa ctatgaggaa agctttgaag attatgccaa attattaact
      541 aagggaatta gtggaaataa agatttttat gcaggagcat taaaagctaa tagtaaaaca
      601 tatcgagaag caactaaatt ccttacagga cggtatgcaa cagatacaca atactatttg
      661 aagctaaatg aattaattaa aacctacgat ttaaccaact atgataaaga agttaaaggt
      721 ccacaaatga gtaagactgg ataccaagtg cctattcata attattcaat aaccagtttg
      781 tttggaaatc gtggaaatga atttcaccga ggacttgata tggcagctac acagggtgag
      841 ccgattcatg cagttaaagc tggtaaggtt gttaaagcag agtttcacta ctcttgggga
      901 aattacgtgg tgatacaaca cgaagatgga tcaaccgcgt tatatgctca ccagcaacaa
      961 tacctagtaa aaactggaga taatgttttg caaggacaaa taattggcta tgtaggaagt
     1021 actgggaata gtactggccc acaccttcat ttggaaattt gcaaagatag tagtctttct
     1081 cagagcatgt tagttgatcc gaaaacctta ttattcggag actaaaaaag gtaatcaatc
     1141 tgacaaagta acaagaaaat ggttggattc ttagaccttt gatcaggata ttgagactgg
     1201 aattgatatc tcgattacga tgggtttgac aaataaaaca agtccattat cgaatatcga
     1261 gtgtattatt gccgtcttta tgctcatatt ttgagcaggt ttcactagat gaaaacaatt
     1321 tatctatctt gaggatttcg tgtacgtatc gttcagtctt gtattgtaaa ttagtcataa
     1381 aatcagacta agaaaaattg gaaatatttt tttctgattt attaaaagtt aattgaaatt
     1441 atatggtact tctttcttgg gagggtaggt gcagtgaagg aaagatatgg tcaccttact
     1501 gttgttgagg agattactca taatggatat aaaaaatatc gttgcctatg tgactgtggg
     1561 aatgaaacga ttgtatatcg atcaaactta ctatcaggta gaaccaaaag ttgtggatgt
     1621 ggaaattata aaaataggca taaatataaa aatttgacaa ataaaacttt tggtaagtta
     1681 gttgcaatca agccaactaa actgcgaagt gaaggaactg ttgtttggga atgtcaatgt
     1741 ctgtgtggga gaaaaaagtt agtatcggca aagcgacttc taaaaggtga tgtaaaaagc
     1801 tgtggatgtt tgaaatcaaa aaagcatcac attgaaaata aaaaattcgg attacttact
     1861 gcaaagtatc ctttggacaa taactgttca tggaaaacaa aatgggtttg tcattgtgag
     1921 tgtggcagta tgtgtgagat aagttatagt aacttatttt ttggacatac tcaaagttgt
     1981 ggatgtttaa aaaggcaaga aacaaggaca tgtgttgaag ggacagtaat agagtgtcta
     2041 acgtcaaaat taccgaaaaa taatacaagt ggtgttaagg gagtttatcg ttctaaagag
     2101 aaatagattg cgtatataac tttaaaaaaa aagaggtact atttaggatc gtatgattct
     2161 attaagagtg cagctcaagc tagaaaagat gctgaaaata aattgtttca acctttgatt
     2221 gacaaatatc gaggtaatca ttaattattg tggataataa ttaacagtga tatataaaca
     2281 tctataatat attattcata ctattgatat ttagtataat cctatggaat tgaatatcat
     2341 agcaatgtat ttgaaaagca aattggaaaa caaataggtg caacaccata aatatgaaaa
     2401 aattgggaaa aagtagaatg gaaatttgct tacgtctcac gagatagctc acactattaa
     2461 tctgaagaac aatgaagtcg acttttagaa attgctagaa gaaagtaaag cgaattatca
     2521 ctagttacta tagagtaagt tcaaataaag catctccaac ttacatggtt acatgaggat
     2581 atcaaatcga aattactcaa gcttcctatg gctagagtcg cgagaagttg ttgggcagta
     2641 gacataggtt atattgttct tagctacacg atcattagaa aggaaatcct attatgtata
     2701 gttatcaaga agatgcaaaa gtccaaaaaa atcgctggtg gattttgatt gctatatcta
     2761 tgtttacctt catgtccaca ttggatggca gtattgtcaa tattgcacta cctaccatct
     2821 cagatgatat gggcatacca atgaatcaag cggaatgggt agtgtccgtt tatctgatga
     2881 ttgtctgttc ttgtttgttg ctgtttggta aaattggcga tagccgtggg aaaatcaaag
     2941 tatttcggat tggtacgctg atctttgtct tgggatcgct gttgtgtggg ttcaatcatt
     3001 cgctaggtat tttattgttc gcacgggtgg tacaagccat tggtgctagt atgactatgg
     3061 ctacaaatgc cggaatcatc acggaagtct ttcccataca tgaacgtggt cgggcattgg
     3121 gagcaatagg tgcgtttgtt tcattaggct cgattgctgg accaggtctt ggcggcttga
     3181 ttttgtccca attttcttgg gcgtacattt tttggatcaa tgtaccggtg ggaatcgtaa
     3241 cgatgttgat tgctgaaaaa ttcttaccaa aagatatcac catgagcggc catacaatcg
     3301 atggaggggg ctttgctgcc attgcggcta cgattatcag cttttttgga gcaatctttt
     3361 tggggcaaga aagtggcttt ttccatccag tcccccttgt actgttcgta atttcagtga
     3421 ttgcctttgt cagcttttta aaagttgaaa agaaagcagc ctctccattg atttctttcg
     3481 gtatttttaa gaacaagatt tttaccatga gcttgattac agccttgttg attttttctt
     3541 ccaacttctt tgtcaatgta gtgattcctt tttatctgca aaatgctcgc gggttgagtc
     3601 ctagctatgc tgggctgttg atgatggtct ttcctttgat gatggtcgtc ggggcgcctt
     3661 taagcggcta cctgaccgac cgggttggcc cggagatttt ggtattagta ggcttgggct
     3721 tattgtcggt aacccaggtc atgtatatgt ttttgtcagt ggactctcct ttgtggctat
     3781 acattgtcgc tactgccatc atgggtgccg gcaatgcctt gttccagtcc cccaataata
     3841 cgatggttat gagctcggtc actatcgaaa acttgggact ggcaggctcg atgaattcct
     3901 ttgcccgaaa tttggggatg gtcagcggga tttcgctttc tacgacggtc ttatatcaag
     3961 cgatgtctgc taagatgggc cagcaagtaa ctaactatat cgcaaatcgg ccggatgtct
     4021 ttttatatgg aatgaagatt acctttttag gcagctttgt tttgtgtttt gttgcctttt
     4081 tcctgactat ctggcgtatc aaaaaacaag gaggtattca gaaaaatgtc tgaaaaaacc
     4141 actgttgaag aatttttgga ggcctgcgta tgggtgagtg ggatttccat ggatgatgga
     4201 agatgaagtg aacttctaaa agccgaaaaa ctcaagtatt atcttcaaaa tactagtgct
     4261 caatgagatg cttgatttga tcacaagaag actgcgaaag ccgctggcaa ccgcaagcta
     4321 ggtatcccac cgatggacta cgttttagag gctactggtt atgaatacgg agccaacgct
     4381 ctcatctgca taagaataca tcacccagat tatgtaaaga ttttcgatac ttctgtcaaa
     4441 aaatcattaa gatagataaa tgatttccgt ctagtcaaat tggttcagaa tgtagacaca
     4501 cagatggtaa gaagtcactc acaattcgag aatggacttg tcctatttgc cgtatacatc
     4561 ataatcgaaa cgtcaacgat agtatcaata ttttgaccaa gggctatgaa tacaagcatt
     4621 gccttagaaa acatcaagaa ccttaggaac aacggggata gcttggttaa taagagatac
     4681 cgctgtttag gcttgcaagt atactctttt atcaagaatt ccgtggcttt agtcatgaga
     4741 ggcttaatac tatgaaaatt ttctttagca tttttgattt aggttccttt tctaattata
     4801 ataagatgac cactacagta acctactgaa atatataaac agccactgta gtaccatttt
     4861 caaagtagtc tatgagagga gaatcttcat tcttatgaac gctggaattg cggatatgaa
     4921 tttaataaaa aaaaccctta atgattttac ttccaattca atatcaaaag gtactggtat
     4981 caatttaagc acaataaaaa agctgaaaag tggtgaaaga tcagtggaaa agctgaatct
     5041 tttagatgct ataaaaataa cggaatttgc tatgaaaaat ggaaaagctg agattgaaat
     5101 atggagataa ttatcgtcta gtgaattact tgccacttag ctgaatttaa cgatccttgg
     5161 tgcttgaagg gggagattct tgggaataga gcatacttgc aagcctatgt ctttactaac
     5221 aacgatatct cttattaacc aagctatccc cgtagttcta aggcttttac ttttatctaa
     5281 gcaataatcg tattcaaagg aaatttttga cccttagaaa gtctcatttt atcagacgtg
     5341 agcttaggca ttgctgaatt ttgttaattc ggttttaggt tgtgctttga gcataatatg
     5401 aaagtattct ttatcacgat ttcattcatc taaggtaatg tgatgtgatt ctgaaattct
     5461 ttcaaaggca gtttttgcat aagctgacat tacatcatca atgacatgtt tacaatgttt
     5521 cactactaaa ataagggggt aaccaagaag aaaaactgaa tgattatttg tatctaattc
     5581 catggtatat caaccatttc ctatatagac tgattatgac atggattaaa ataaaaaggc
     5641 actatgtctt aattgtcggt tttcgagtta ccgaatggca ttcatcaccc acctatagag
     5701 gatgggcgac ttctgcctga aataagttac actacttata acttctaata aaattagatt
     5761 gagtcattat tatttaacat caacgatttt ccagtttcca tttttttgta atactaattt
     5821 gtactgaaag tagctagtgg tttttgatac attatcaagg tattttatct ttgtactcac
     5881 tagaaaattt tttccgtttt gtagataaac tggattctct aactccgaaa actttaagtc
     5941 aatattgatt ggtcgcatcg caccattttc aacataatac tccaattctt tttcagaagc
     6001 tgatggataa agtttaaaaa atgtttctaa aaaatcggtg atttcttccg ttgttttggc
     6061 atcaatttct gaatcgtttt ctacttgttt tgcttcatat tttgccttgt ctggctttcc
     6121 aatcattgtt ggcaaactag ttactaaatg attcctgttt tcatcttcaa agattgtcac
     6181 tcgatatgca gaagaaattg attgcgtctt ttttccctct gtaatatgtt gctccactaa
     6241 aaatgaaacg acaaattctt ccgagtgttt ttcaacatct agaattttta cagattgaac
     6301 ttcggaactc gtgggaatat ctgctcgaac catatcttgg attaaagcga gaccgttttc
     6361 tgtaaggtac tgttcgagat tactcattct cttttcaatt gcttctttgt tatttttcca
     6421 tgaaaaatat tctttcgcaa aatcctctgt aaaactttca acgccagaag tattcactac
     6481 cttctctttt ataaccactt tttcatgagt tgtatgttga tcaatggcgg tgaaattttt
     6541 ataaacgcca aaagcaagac tacaagacaa taaaagccaa agggcaagca ccatttttcg
     6601 atgcttaccc acggatacaa ctcgttcttt tttctttttt gggctctttt ccttttgatt
     6661 ccgttcaatt tttatcttca ttctttttcc tcttttctct tatttgtatc ggccagctcc
     6721 gataagatgc tgccgccaat agttttccgt tagattcgtc caccccactg gatctcctgc
     6781 atgaaacatg cgattctccc ctgcgtaaat gcccacatgg gtcacataag taccggcatc
     6841 ataggttgaa tgaaagaaaa ctaaatcacc tggtttggca tcttttagat caatatgagt
     6901 catggcatca tattgatcct gagccacccg aggaagtttc aggtcaactt tggcataaca
     6961 ccattgggtc aagccactac aatcaaaccc cgtttctgga cttgagccac caaacacata
     7021 ggccgttcct tcatacttaa atgcctcatc aaaaatttct tggactattt tgtcatcaaa
     7081 ctgagttgta gttaggtatt gcttcactaa taaacagtaa aacatattgc cataattata
     7141 ccgccaccca ccattttcct taatcgcgat tgggttgggg taatcgactt tttgaccacc
     7201 tgatttttcc tttgaaaaag attcagctaa agcaaaacta tgcttcttcc cgtttttccc
     7261 gacatgatct agatacccgc caccatagtt ataggcctga ataatactat cttgatcaca
     7321 ccctagttct ttggaacgct taaccaaaga cgcaaaatag agacagcctt gtttgatgga
     7381 tgcctcggta cttaatgaat taggtggtaa tccggctgac tcagaacttt gcataacgtc
     7441 ttccattgtg ccaccagatt ccacttgaat aatcgccaaa agaattggaa tatactctgt
     7501 tatatccgat tctttggcat acttttccac cattgcacgg tgtttcaata cttcttctga
     7561 gacactagtt ccgccaggag aagtgccaga actaccattt ccctcactgt cttcaccaaa
     7621 caacaaaccc acacacatca aaatacccat aaaagagatg gtcagaaaag ttaatgaaat
     7681 aacacccact ttcttcaagt tcattttttc tcacctgacc ttgattttgg acgatggttc
     7741 attctttttt gtactttttg attggtctgc tttggcagag tggacctctg tttcacttgt
     7801 tggaaagaat ttttcttact tgctgattgg cttttccctt ttgaaatgat ttcttgacta
     7861 gttagttttc gtttgatttc gggattcaga tttgctctca caatccgctt tggtgcttct
     7921 tttttcagca tcatatcttt ctgaggttga gctgctttat ctattggaat attcgccctt
     7981 ctttttccct gacgatttgt tgcttcactc agtatcttgc gtttttcgtc cattttcgca
     8041 tttcttcgtt gtcgttgttt ttctcgcaaa tccactcgat ccgctttttc ttggaacagt
     8101 ccgcgcttga attcttctgg tgcttttttc gacttttcga ttcctttatg gagattgtat
     8161 ttcaaattcg ttggcgtatt ccttacctga tcctttactt gtttagtctt atctttcacc
     8221 aaagcttggg tatccaaaac tttgccgatt tttctcccag ccaaattcat tcgggattgt
     8281 ttcttattat ttgaaactgg attctcctta gttaagtcag atagtatttc gtgatcgttc
     8341 ggtaatcgtg aattctttcg tagagaagaa ccggatggct taaatttgga ttttgattgt
     8401 tcctttgcca acttatttcc gactgctgca ccaccaccaa aagccaaagc tcgtcccaca
     8461 tttcgattga gttgccgcaa ttttcgattc attaacattt gcggttttcg catgacgcgt
     8521 cttcccattg actggctatc attactctgg aggttgaaca tactcataat gtcgcccaat
     8581 ttgaaataga taccggcaaa ggtcacaatt tgcagaaaag caaccatgaa aaatggatag
     8641 gttgccgaaa tattgaaaaa catcgtggag atgctaaatg cagtcgtaat caccaaagta
     8701 acacccgctc gcatcataat cgtattgaat aaacgaataa tcgccttctt tcctaaactt
     8761 tcataagtcg gcaacatgga caataagaaa ctaattggca gaaacatcgc aaagataatg
     8821 aagagaattt gcgagaacaa cataatccct gttagaagaa aaacaaagaa ggaaatgcca
     8881 atattgaaca ataccaaaaa gaccacggtc cctaaacggt tcatggtctt ggtaatactg
     8941 agattcgcat tgtcattgtc ttcaatctct gccttgaccg cttcttcccg atctttgcct
     9001 ttgttttcat ctggactcac agatagaatc ttgttgaccc ggtcttcacc aatttcttct
     9061 atgttggaat catcaaattg cagtagtaac caaggttgtt ggacttgaat cgaaaacaaa
     9121 ctatcccgaa tcaaatccac actatctttt ccttggcttt ctgaattggg tacaacgatc
     9181 tcggttccaa gggtaagggc cgcttcacta acatctgagc taaagtcatt gatttttgtg
     9241 atataggtag gcgcataagc aatgaacgaa cccgatagta gaaaaatcat cacaaaatta
     9301 atcacggctc gaactgcttt cgtggtttct cgttttaata atccggtata cgccacatac
     9361 acccccagag ctaaaatcat caataataga aacccaaaat aaaatccgga ggtctggagt
     9421 ccattttcag taataccagc caatgtttgg atattctttc caatactttc agccgtatcc
     9481 gaaatgaaat ctaatttgta agcctcttga accacataac ccgtggcgtt cgacaaatac
     9541 aaactcaccg tccaaatgaa attagtaatg gcataaagac catacatcac gcttttccct
     9601 aagccatcac cccaattcca aggcaaccaa tcccaagagc tatccacaaa gaaatctagt
     9661 tgatagttgt tcagtgaata tttggaatat agatttcctg cttcaactgt atcatcaact
     9721 agccctgtcg cctcggctac cgtaccaact aaactcaata gaactatcag agtgagtatg
     9781 ctaataaaaa cgattcccac aatccgaaaa agtttctttt tcatcccctc actccattct
     9841 ctcttgaaca ggtggacggg tatcaaaggc atggaagagt tcttcaaaga ctggatgtac
     9901 ctgaaccacg cctacccgac catacaaatc ctgcatcaag cattggccat tttccaaatc
     9961 tcgtaggcgt ttttgattgc tttcatcttc tcgatccaag ccaaagaatt ccaaggtttt
    10021 cttgatttca tgaatatcgg tactgcgaaa cgcaaacttc aacccgatat tattcttcaa
    10081 gcgttcatcc agtaaatcat cactattttg cgtgacaaag taaaccccgg cattcatagc
    10141 ccgcccagca cgaacgagct tattcgataa tgttttccct tgcgctactt gaagaaaact
    10201 ccacgcctca tctaagtcta caattttgaa gatttctcga ttactatgga taaagtccaa
    10261 ggcaaaagtg gaaatgacga ttagcatgga aacactaagc aattccatgg tggtatattc
    10321 ttcaaaagtg gtttctgcat ctggtaaaac caaatccgct acttgaatga tatttaactg
    10381 cctatctaaa ctaatcgact gggtaatcga accatctgag aaaagcaaat gggcaaaatc
    10441 ataatcggta aaggactcga tgtgatccgc gatattttcc gcaactggtg agccttcttt
    10501 tcgaagctca ttaattactt gtaataatcc ccgttgattg ctttgggtaa ccgtccgaat
    10561 ggccttacgc aacactggaa acttctcccc atctcgacta gaaattcctg ttaaaaaggt
    10621 cagaatatca attgctagac tttcagaatc cttctttttc tccataatca cataaggatc
    10681 aagtaatcct tgattttttg gcttactagt taagttgaga atattgattt catccgcaat
    10741 ttctggcaag gtttctttcc agccaccccg ttcccctttt ggatcgacaa tcacagcttg
    10801 tccaccaaaa aggacggcgt aataaactaa gagattgtta ctaaaggact ttccgccacc
    10861 gagtgaaccg aggaatgccg ctgctagcgc attggtaact gaatccttga ccccttgtga
    10921 ggccaatgcc ggtttcaggt aaacattgcg ccccgtatct acgttataac caaagtaaat
    10981 gccttccaac tcccctaaca tctgagtggc gccaaaacca agtccggcga gaaaatcaga
    11041 cgtaacatac tggatataat cattcatgta tcgcttacta gaaggtaaga attcttcatg
    11101 tagccccatc atatcgccaa aaggccggac tagttttaca ttggtatcat cataaaaatc
    11161 tagcacttca tcacaccggc gctttagttc atctactgat tcggcactta ctcgaaccac
    11221 atagctcagt ttgtacatgg attctttgga ctgatccaag gtagtttcca attcatctac
    11281 ggaatccaat gcatctaaga cattggaatt tgtttcattg tcagattgat aggcatggtt
    11341 gtccaagtct tttaattcct ttttcttatt gcgaacggta gcaagtgcct ttttgttcgt
    11401 cacaatctcc acattcatac tagtgtcaat tgggaatgta aattgttgtt gctggtaata
    11461 gaaaagttct gaggagggaa actccatttc ccccacaatt gtattaattg ttaagtacgc
    11521 tacatatgat tcatgattct catgttccat gcataagtac cggggctttt cttcaatcaa
    11581 acaacgactg ggacgtaata agtcgtaacg tttcaccaaa gtttccgact tcagcttttt
    11641 ctttggtagc tgaaattcat attcttcaaa tggtgtaccc ttttcgccat agatatgttc
    11701 aatcaaatac atcagatcac tcggtgtgac tcgtctgact ttaaatcttc gagccaattt
    11761 actttccatt agtttttcaa gcttggtata tcggcgaatt tcttcattgg ataaggaaac
    11821 aaaatcgccc atcaaatgat gattcactcc atagacaaat tcttgaaagc cggagaagaa
    11881 agatttcttg agattcttta gattgacctc ttcatctgtc gcaatcagtt tgaagccaat
    11941 aaaaaagcga taatcaatct gactatcgcc aatcatggat actaatgcct ctgtctgtaa
    12001 atcaattcgt tgtttcgcta cttctgttaa tcgcccggta atttcctttt ttgatcgttc
    12061 ttgcgtggca cgaatactac tttctgtggc aatttgtaag gcatgaatct tgccttcacg
    12121 attttgcgca atcaattgac gaaagttatc gtggacttga tatttctgtt caggtgacaa
    12181 aaaggagtaa ttgtaaggta ttaactcata gtaggcaaaa cattctccct cttgattaaa
    12241 gacaagatta ttttcaatat acttaatcgg gtacatagtt cacactcctt accagagtaa
    12301 tgggttcgtc ccatcgtttc ttctgttctt tgactttctt tcctgcgaaa gtgaccttaa
    12361 atcgtaagtg atagctaata aaagatcgta aaaatcccaa tggtttctta ccgtcaaacg
    12421 ttttttgcga catgaaccaa gtaactgcca ccggtatacc taagtatttt aaaaaggccc
    12481 cctctatcat agatagtgga ggcacatggg caaatacgat gacaaacagc aaggataaaa
    12541 caaaccaagc catctggtta aaagtcacag gaaaaggcag ttgaaagtca ttaattgcat
    12601 aaatgacctt ttcaactgcc caaatactgg tgtagctttt tattttcttc atcaaatcat
    12661 tcctttaaaa agaaggatag tttagaaatc aactaccctt caataatttt gttaatatgg
    12721 atactcaaaa acacctcgac tcgttaccaa ataattgcct ccaatctcca agtctctacc
    12781 acacgcatca aaatcaatat acgtcttcaa gtgttctggt acttctccaa aatcaccagc
    12841 ttctacaatc aagaaatatg ctacatcact catatcatcg caatctggat aatagataat
    12901 atcatccaca tgctctacca tctcctcaaa agaattgaag aaagcatgtt gaatctcaga
    12961 agcaacttca ccaactggcg ttccttcaag ttcctccgct aagccacaca accgattaat
    13021 ttcctcaatt ggcgtatact catcaatctc aaagggaagt tcataatcat gaattgcata
    13081 ttcctcgtat tcgtcattta acccaattcg ttctttcact tcatcaaaat cgacaggtgg
    13141 ggtaaaccac gcccccacca attcaccttc gttatatttc ccgaggttcg caatataaac
    13201 acgcatctgt tccatcgtgc ttccccctta cgcaccgaca attcggttaa acaaactgag
    13261 taagacatcc ttcaccccag aagcattaaa gaccaatccg accgcaatca aagcaatcac
    13321 caaaaagcca atcagtttgg aaaactcccg cttaaatcct aaaaacaaac caatgaccac
    13381 aattgccagt aagactaagg attg
//
LOCUS       DAFLWC010000079        13306 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.080, whole genome shotgun sequence.
ACCESSION   DAFLWC010000079 DAFLWC010000000
VERSION     DAFLWC010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13306
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.080"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..124
                     /locus_tag="L1V17_002241"
     CDS             <1..124
                     /locus_tag="L1V17_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HBN1236985.1"
                     /translation="AAAVAGLVASVKKTVIDPIDEKEAMIEENRKKAMRKRVSR"
     gene            complement(186..1997)
                     /locus_tag="L1V17_002242"
     CDS             complement(186..1997)
                     /locus_tag="L1V17_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HBN1236986.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(1994..2359)
                     /locus_tag="L1V17_002243"
     CDS             complement(1994..2359)
                     /locus_tag="L1V17_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HBN1236987.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(2522..2917)
                     /locus_tag="L1V17_002244"
     CDS             complement(2522..2917)
                     /locus_tag="L1V17_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBN1236988.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(2935..3897)
                     /locus_tag="L1V17_002245"
     CDS             complement(2935..3897)
                     /locus_tag="L1V17_002245"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HBN1236989.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(3897..4109)
                     /locus_tag="L1V17_002246"
     CDS             complement(3897..4109)
                     /locus_tag="L1V17_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HBN1236990.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(4130..4828)
                     /locus_tag="L1V17_002247"
     CDS             complement(4130..4828)
                     /locus_tag="L1V17_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HBN1236991.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(4848..5390)
                     /locus_tag="L1V17_002248"
     CDS             complement(4848..5390)
                     /locus_tag="L1V17_002248"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBN1236992.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(5522..6526)
                     /locus_tag="L1V17_002249"
     CDS             complement(5522..6526)
                     /locus_tag="L1V17_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBN1236993.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(6523..7512)
                     /locus_tag="L1V17_002250"
     CDS             complement(6523..7512)
                     /locus_tag="L1V17_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBN1236994.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVEKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(7509..8315)
                     /locus_tag="L1V17_002251"
     CDS             complement(7509..8315)
                     /locus_tag="L1V17_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1236995.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            8481..9437
                     /locus_tag="L1V17_002252"
     CDS             8481..9437
                     /locus_tag="L1V17_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1236996.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(9514..10032)
                     /locus_tag="L1V17_002253"
     CDS             complement(9514..10032)
                     /locus_tag="L1V17_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBN1236997.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(10120..10269)
                     /gene="rpmG"
                     /locus_tag="L1V17_002254"
     CDS             complement(10120..10269)
                     /gene="rpmG"
                     /locus_tag="L1V17_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBN1236998.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            10497..10943
                     /locus_tag="L1V17_002255"
     CDS             10497..10943
                     /locus_tag="L1V17_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBN1236999.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(11138..13033)
                     /gene="asnB"
                     /locus_tag="L1V17_002256"
     CDS             complement(11138..13033)
                     /gene="asnB"
                     /locus_tag="L1V17_002256"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBN1237000.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
BASE COUNT         4140 a         2826 c         2267 g         4073 t
ORIGIN      
        1 agccgctgcc gttgctggtt tggttgcttc tgtgaaaaaa acagtgatcg atccaattga
       61 cgaaaaagaa gcaatgatcg aagaaaaccg taaaaaagca atgcgtaaac gcgtttctcg
      121 ttaataatta tttaaaaata cgcatgaaga ctttctaaaa aacagataag tcatcatgcg
      181 tatttttatt tgtcagtcaa tataagttgt gctattttat ctgcctgtct cagattccat
      241 ggatctgtat aaggtctagc tactgctgca gttagccaat ccacaccttc aacaggtatt
      301 ccatagcaat aaaagtcaga ctggatttcc cctgaagcat caatcacgcg attcgtacct
      361 cgctcaacat ctatagcttc tgaatgataa cttcctgtat tatctgaaaa tgaaaaaggg
      421 cgaacaagtt tgttttcctt caaatttttt atgacaggat tacttgaacg agaaaagctt
      481 gtttgtggca atcgagcttc aatcaaatag cgactgctga tttctttatc ttgtagagaa
      541 ataacatagc ggttgtgctt ttgctgaata tcaaatggcg gttcgatcaa atgaaaaata
      601 cccgcatcta tcagtgctgc taattctttc gtccgaatga ttggcggacc gatcgttaaa
      661 aagctattta gatgagtaaa ccatccccat agtatttctt tgtattcctt agcagaaaaa
      721 acgtgccatt caatagcctg ccggattgga tcacgccagt cttttaatgc atcaaatgtt
      781 gaagcaaatg ctcctgtgca attgcctttt tccgcttctt ttatctgccc ttcaataaat
      841 attcggctag cttctgaaaa gggctcattc tgataggcaa gaggagtttc taaatacgac
      901 caatcccatc tataagggat tagtgctgga tgctttccga gacactcctc tgaagagagg
      961 gagagaaaat catgctcaaa atttttcttt ggaatcggca agtgatattc ttcgatgatt
     1021 ttcttgtaat aaaacaactc aacgtctttt ttcagatagt caaaaaatgt ttcgccagtc
     1081 aaaaatcccg actgatgcca ttgctccagg ttttcttttg ttagtaaccg tggccatgcc
     1141 attgctccgc cttgcttttg atttcttcct cgagggtaat aagggagccc ccttcttgat
     1201 ccactgtata caatcggttc cttgcctgat ggatgataga ccagttttcc cttttcgttc
     1261 tcgaagcgcc ctcctcttga tactgtaaac aatccgacat aatcaaaaaa acttaagcct
     1321 agacctctta aaaagacatt ttctttaggc ggtatcttcg aaagatctac atctgcagga
     1381 ttagaaggaa gctgatacag taaaacattt ttctttgcgt agtctaccca cactctttct
     1441 tcttctgtct catcattttc ccagtgaccg cttgctaaaa caagctgatc gatagaatag
     1501 ctttgctgat ctgtctgtaa aagataacca tcttttcttt tgcttacttt ttttactaaa
     1561 gaataaacaa actgaataga agctggaaat tcttcttgca actttgagaa aaaccagcgt
     1621 tgatagagtc cgtataaaca tcgagtagat tgctgatctt tttccagacg attgatttct
     1681 tctataatta gttgcttatt tttggttacc gtctgttcga tataatctgt agcaggtcct
     1741 ttactccatt gaaacaagtt gggtccctgt gttaccaatc ctccactgga caatgtttca
     1801 tctgtaaaaa gcgtcacttg ttgagaaaca gaattcatta ataactccgg tggctgattc
     1861 aaccgccaaa ctcgacctcc aggaccattg ggatcgaaaa gaaaaagttc aagagaatgt
     1921 ctgtcctgat tattatggag aatcctttct gctacactta atcctctagg tccggcacca
     1981 atgatcccta ttttcatttg catgcctcca tttcgataaa ttttttcaat aaaacagcat
     2041 ggttctgatg ttcatttttt gcaccataaa caaaagtaat gactggatgt tctttcataa
     2101 gttgactgag tttaaaaata gcttgcttct tttcttcttc gaaaatcaat tcttgctggt
     2161 atttctttgc aaatgaagca aatcgttctg gtacatggtc aaaagttttg cgtgcttcat
     2221 tactaggtgc aatttctttc aaccacagat ctaactgcgc tttttctttt gaaattcctc
     2281 gtggccagaa tctatccacg agtattctat agccatcctc tttttcagca tcaaggtaaa
     2341 cacgttttaa tttgatcata gttgtttcct tctttctacc ttttcgctta gcttatatat
     2401 gtagataata gcacaaaata aaaaaaatga acggcacaac tatccattgc gccgttcatg
     2461 tgatcttggt caaaatctaa tgattgattc ggtttttaaa gctgtcatac aatcatctgt
     2521 tttatacttt tttacttttg atttttccag accatccgtc atatccaccc ttaagtaaat
     2581 aaatctcttg ataacctgct ttacgtaatt tatttgctgt acggatgctc aaacttttct
     2641 tttgatcgta aatatagaca ggctggtctt ttcgaataga tcctaatgaa tctttcaaaa
     2701 cagtgtaagg gatgtttctt gcacctaaaa tatgcccagc atcaaacaca tctttttcgc
     2761 gaacatcgat tacttgtgct tttctcattc cttctcgaaa ttcttcttct gtcaaagtcg
     2821 ttgctgaacg tttggccatt actcgtagat agacttccca aaggatgatt gcaagcacaa
     2881 tcaatagcaa aatgatatta attacccata aaaccatgta atgcctccgt ttttttaagc
     2941 aaatttcaag gctaatgagg cagcaccaat gacaccagct tcattaccaa gctctgctaa
     3001 tttgattttt gttgattctc ttacttgcgg gaaagtaaat tctttaaaat atttctctac
     3061 acggctacgt aaaaattctc ctgctgccga tactcctcca cctaacacga tacttgacgg
     3121 atttaatgta ttccccaagt ttccgcaagc taaacctaag tagaagcata cgcgatcaac
     3181 aaccatcaat gcaaacggat cgtcttcttg agccatttca aagatatctt tacttgttac
     3241 ttcttctccg ttgtctagca ttgctttcag ttttgaatcc cctgcgtatt cttctgccaa
     3301 gaaacgacct aggcgtacca cacctgtagc gctagataca gtttctaaac atccgcgttt
     3361 accgcaagta cattcgaacc cttcaggatc cacagtgata tgtccgattt ctcctccagc
     3421 tccgctcacg ccgtgaatca aatttccgcc agcaacgata cctccgccaa cacctgttcc
     3481 tagagtaacg aatacaacgt ctggatcgtt ttctccagca cctttccatc gttcacctaa
     3541 agcagcaaca ttcgcgtcat tatcgatagc gaatttgatt cctgttcctg cctcgatcag
     3601 ttttttcaca aattgaactt ctgtccagtt taagttatac gcaccaataa ccgttccagc
     3661 ttcgctgtcc acgcttcctg gggtacccat gccgattccg ataaagtctt cggctttcat
     3721 attatataaa ttcaaacgat gattgattga ttcaatgatt tcaggaacga tatgcttacc
     3781 atcatccaaa atattggtat cgatgctcca tttttgctga atctctcctt ctggtgttaa
     3841 aattgcaaat tttgctgttg ttccacctaa atcaatccca ataatcttct tgtccattac
     3901 aaatttcctt tctttcggct ttcttcaatt cggtgctctc tttttaatat gcgccacgct
     3961 gtcatgtatg tatcatgatc aatcaaacgg ctatcataca gattacgcaa ttcgatagtc
     4021 attaattcaa tgtcatagat gcgtgcaccc acatagataa agatgccaaa ttttttgaac
     4081 agctgctgta catcatataa gctctccatc tttaagcact tccttcatat tatacaagta
     4141 aaccatattt ttttaaaccc agtaaaatac atattacaaa aagaaataca aaaactagtg
     4201 tagaaagaat cctttggtgt atcgaatagc ttgtctgttg tttcggtaga cccaaaacat
     4261 tccctaacac taatccgcca attagcccac cgacatgtcc ccaaacatct acagaggtat
     4321 ccagaagacc aaaaacaaat gtcaacacaa taaataaaag aaaatgtctg actagctgct
     4381 ggatcgctgg gttatgttta aaatgaaacc ctaagataaa caacgcaccg aacaaaccga
     4441 atatcgaagt acttgcacca ccagacagaa cattcgcttc gttaaaagca aagcttgctg
     4501 tatttcccat tatcccgctg aacatataaa tcaagaaaaa acgccaatgg ccatagattg
     4561 cctcgatttg ctgccccata aaatacagta tcagtgagtt cattacgaaa tgcatcagtc
     4621 caaaatggat gaagattggt gtcactaaac gccaccattc attgaagtga acaagataag
     4681 gaccatacat tccggcataa taagggatct caagtcgcgg aaataattcc atcatgagga
     4741 agaccgctgt ctgtatccct aaaaaagcat aggtccataa cggtcgtctt aaccatgcac
     4801 gcaattttat ttgctgttga taattcatga aaacctccca tttcatttta gtcaataaac
     4861 aattgttgga tcttctgatc aaagctctcc ggttgccatt gttcattcaa ttgttcacga
     4921 aaaacaaggc tacatgtttt tttatgaaaa ttatttaaat accggtcgta ataaccaccg
     4981 ccaaaaccga ttcgataacc ggctctattg tagataatac ctggtacaat gaggagatcg
     5041 atcatctccg gcaaatagag cttctctgat tgtggctcaa gaacaccaaa actcgaacgt
     5101 acaagaacgg actgttcatc catttcataa aacgccatct gacgtttcgg caaagtttta
     5161 ggtacaacta ttttcttttg ttctttttct gctcgttgga taaccggctg tgtatccagt
     5221 tcaaattcat tcgataaagt cgtccctatc acttttgctg acttccagta ctcgctggcg
     5281 aatagctgtt tatagattcg ctgttctttt tcctttttct tgccactttt ggccagattt
     5341 ttcagctttt cgattccttt ccggcgtaat cttactttca attggtccaa aaactcaccc
     5401 ttccttctct cataaaatgg tataggaaaa aaagaaaaat agcaatcgaa ctttcaaata
     5461 aatgcataaa tagaataaaa agaagaccta gaaatgattg gccttccttt tttaatgaat
     5521 ttcaactgtt cagcgcgtgt ttttgtctga taaaaagtgc atacagaaaa tatggcgcac
     5581 caaaaagggc aatcaaaatt cctgtaggta cttccccact tggtagaatc actctagcaa
     5641 ccatatctgc actaagcaga aaaatggaac cgaacaaacc gctcagaaca aaggtccagt
     5701 tattttcttt acgtacgact agcttcgcag catgaggagc tagtagtcct acaaaagata
     5761 aactacctgt caccgctaca ctaccgcttg ccaaagcaac agctaacaac aaaaggattt
     5821 tttgactttt agccacgtta aggcctaatc cttgcgcgcg ttcttgacca aatgatagca
     5881 atacaatcct ctgtgcataa agtcctccta gcggaattaa gataaccgcc catggaagca
     5941 atgcccaaac ataaggccag ctcgcacccc agattgatcc cgctaaccat gcattcacaa
     6001 atccataatt ttccttagat aattggatcg tgcatagcaa tgttaatgca gaaaggccgg
     6061 cattaacggc aataccggac aataagattc gattcatacc caaaaagcca tttcgatcat
     6121 aggccgcaag atagacacag caagcagcta aaacaccacc tagaaaggct acaactagca
     6181 atagaaacgg cagcgaatag tgcgaaaaga aacctaaata aagcatcact aaaaatcctg
     6241 ctccggcatt aatgcccaat atactagaat ctgccaattc atttcttgtt actccttgca
     6301 agatataacc agaaacgcca agacaagctc ctgctaataa actgatcagt aatcgaggaa
     6361 ctcgaaattc tctaacaatc agcgccaaag aagatgattc tttccctatg aacgtggcaa
     6421 aaagctgatc caggtaaata aaaggcgtac caatcattaa actacctata gacaggatga
     6481 caagtacaaa aagcaagaaa tagaacgtcc aatatatttt tttcaccgtt gttccctcct
     6541 tacttgtatc agtaaaaacg gaacgccaat caatgcaatg actaatccaa aaggtgtttc
     6601 aaaaggggga ttgatcatcc tcgctgtaaa atccgccaac ataaccaatc caccgccaac
     6661 taaaaaagag acaggtagaa cataacgata gtccgttcca accattccgc gaacaactgg
     6721 cggaaccaac agcccaataa atgaaacagg tccgactaac gaaacggcaa tggctgctaa
     6781 cactgcaact agacagaaaa caatcaaccg cgttcgttta ggatgacttc caagagctaa
     6841 tgcatgtgtt tcactcaaat gaatcaaaga tattgctttt cctaatgaaa aagaaaccaa
     6901 aacagcaagt atatataaag gaaacaatac tgctaattgt ttccatgtga tattggcagc
     6961 tccgcctaca aaccaaaaag caagatcctg ctgcagatta aagaattggg taagtgcttg
     7021 gctgatagca gtaaaaaaag aactaatagc tacgccagct aaaatcagct gtaaaggatt
     7081 catgcccatt ttcgaaaact gcaaaaaacc aaatacgagc aaagttacag caaaagaacc
     7141 tgccaatgac attagaaaca cagaaaaatc agaagcttta ggccaaaaag caaaactaag
     7201 ggccattgcc aacgaagcac ccgcgttgat tcctagtaag cctgaatctg ctaaaggatt
     7261 tcttgtcact ccttgcatca atgcaccgct caatgcaaaa caactcccta caagaaatgc
     7321 tcccgccaca cgaggcaaac gaatatttcg tatgatttgg tgactttgtt ttgatctatc
     7381 aaaatcaaac aacgcctgcc aaaaatctgc tttttccaca gtcgctgcgc catttgaaag
     7441 agcaacaaaa aaaataatca aaagaacaaa acagaccaaa agcaggagtc tatttttctt
     7501 catagtcctc ataattgatc ctcctgctct tttggcaaca aatcataggt tagaaaaact
     7561 ggtttatttg ttcttggaag cgtgacaatc gttgcatcaa tctcaaatat ttttttcata
     7621 cactcttttg tgatcacttc ttcaggtgta ccttctgtga tcaacttacc gtttttcatt
     7681 gctaataaat aatctgaaaa acgtgaagca tgattaatgt catgaatcga catcaagatc
     7741 gttgtttgtt tcatttgatt gatttcagtc aataactgta ggatctctaa ttggtgtgcc
     7801 ggatctaaaa atgttgtcgg ttcatccaag atcaagatat ctgtttcctg agcaagcgcc
     7861 atagcgatcc agacacgctg ggtttgtcca ccagacagcg ttgcgatatc ccgcatacga
     7921 aatccagcta gacctgtagc atccaacgcc cactcaattg cttcatgatc ttgcgtgtcc
     7981 atgccactga acagtttttg ataagggtat cgtccgtaag atactacttc ttctactgtc
     8041 atacctgtag ggtgttcact agtttgtgct aataatgcaa ttttttttgc aagttctttt
     8101 gaactgtatg tagagatatc agagttattg acaatgatct ttcctgattt cacaggtagt
     8161 atacgggtaa aacttttcaa taaagtagat tttccacttc catttggccc aatcaaacta
     8221 gtgattttcc cttcaggaat cgtaacagac atgttttcaa tgattttttt gttttcgtag
     8281 ccggctgcaa tgtcagctgc tcttaatctc gtcatttcac ccatcctttc gctgaaaatc
     8341 attctcaatt atgacgctgt ttcaacattt cgtcaagcgc tactttcata tctatagcca
     8401 aatgaagcgg ttgacagcgt tcgaaatatc aggaataata accaatgaga aagattctca
     8461 attatgttag gaggaaagaa atgaaattaa aaacaaaagt attcacatta tctagcatat
     8521 tgctgctggc tggagtactg agcgcttgct ccccctcttc agataaagaa acagctacaa
     8581 ctgccaattc gacgacttca tccaatagta ctcatacagt cacagataca cttggacata
     8641 aagtagagat tccaaacgcg cccaaacgga tcatcggcag ttacttagaa gactatctga
     8701 ttgcactagg ggaaaaacct atcgcccagt ggactgttgg cagtggttcc attcaagatt
     8761 atctgcaaga tgatttaaag gatgtcccaa cgatttctta tgaccttcct tatgagaaag
     8821 tgttaagctt tgagcctgat ttgctgttga tttcttcttc cgctactgtc gaaggcggga
     8881 aatacgaaca atatagcaaa atcgcgccaa cttatgttgt aaaaaacgga acagatgtca
     8941 catgggaaga acaactaaaa gatgtcggca aagctttggc aaaagaaaaa gaggcagaaa
     9001 aaatcatttc cgattatcaa aaatccatca agaaaactcg agaagaacta gcagataaaa
     9061 tcgagaacaa gacagctgca gtgttgtggg tgaccaacaa ctcagccttt atggtcagca
     9121 aaaatcggtc aagtggaaga atcgtatacg acgatctgga atttggtgtt cctgatctag
     9181 tggaagaggt ctccaaaaaa gccacttctg actggtctgc tgtttcctct gaaaagctag
     9241 ctgaattaga tgctgactac atcatccttg tgaacagtga caaagatgct gccatgttca
     9301 atgaaccaag ctggaagaat ctaaaagcag tgacagacaa tcatgtactg caattcggac
     9361 ctgaatctag ttggctatat aacggaccta ttgccagtca ggaaatggtc aatgatatca
     9421 aagaaaaact aaattgattt taactaaaaa aagcatcttc acgattagtc gtgagatgct
     9481 ttttttctta ttaacaaact agacgcatag attttattct tcttttgaag caaccctatt
     9541 ttttactctt tcccattttt gaaaacgatg ggcatataga ttttcttgat ccgttatccc
     9601 ctcatactcc tctataaggg cgaagtctga aaaatcaata ttcccaatat acgtatcgcc
     9661 ttcaaacgtg ctatcgatca atgttcgcca gatccgacca gtgtaaggaa gaagttcttg
     9721 aaaaatccga ctaccacccg aaacatagat atcttctgag atcgtttgac tatacgacaa
     9781 aagttcatcg atcgaatgca ttacttccgc attttctttc gtgcgaaaat ttggttgcgt
     9841 tgtcaacacg atgatatggc gataaggaag tgaaagatcc cccattcctt cataggtctt
     9901 tcttcccatc actaaaattc gatccattgt atgttcgcga aagaaacgca tatcatttgg
     9961 caatcgccat ggtaacaaac catttttgcc gatcagacca tttttatctt gtgcccacat
    10021 ggaaataaac atattatccg ctccttatga ttttagatgt tttgagataa aaaaagtctc
    10081 aattctttga ccagcaagga attgagaact ttaaaaacat tattttgttt cacggtgcaa
    10141 agtaactttg cgttcgcgtg ggcaatattt ttgtttttcc aaacgatcag gattgttacg
    10201 tttgtttttg cttgttagat agttacgttc tttacaagaa gtacactcta aagtgatgtt
    10261 tacgcgcatg tttttccctc ccatttttac aagaatcctc taagatgact ctcagacttg
    10321 attatcttac catgattttt tctagattgc tagtgttttt cacgattttg ttaagtaaaa
    10381 ctacttgacg ataaatacaa cggttttact tctcaaacaa aatctttttc tttttgtata
    10441 aataccctta cacttgttta tatagattat gttttttaat aaagggggat actaatatgc
    10501 catggaacat gaaggacttt cctgcatcaa tgaaaaactt agataaattg acaagaaaaa
    10561 aagcaatcga catcgcaaat gcattattag atgaagggta ccctgataac cgtgcgatcc
    10621 caattgccat tgatcaagca aaaaaatggt atgaagatgc tagtgaatca gaaaaacgaa
    10681 ctttcgaaaa agaaaaaaat ccaagcaaga cggatgaaca cgatacgaat cctcgtgctg
    10741 gaaaactgct tgattcagat gtgatcgtag aatatgagga agaacaatgg atcgtgaaat
    10801 ctaaaggggc aaaaaaggca agcaaccatt ttgatacaaa aaaagaagca atcgaaaaag
    10861 gaaagcaagt agcacaaaac aaagaatcaa ctttgttcat ttataaaaaa gatgggacaa
    10921 aagaaaaaga aatcgattat tgaacatatg taaaggggtt gtgacgaaaa tcgtgtcaca
    10981 acccccttat gttcgaaaca atggtgttcc tctgccaact ccgaaccata agtcataata
    11041 tctataaaac gggaagagct gttttttgaa attgtttctt atcactcagt gttaaacggt
    11101 aggagaaaac ctctttttta ttgatatttg attttcatca aacagtcaca tagtcgattg
    11161 cttctgcttg cggaatcgtt tcatctacaa agtagacttt ataccatgtc aagaaactga
    11221 agattgtcca gatttttctt tgctcttctt tacgtccttc gtgatggtca tctagcaact
    11281 tcatgatttt ttcttgatca aaaaattctt ttgcaaaatc tgcttcgaat aatgctttga
    11341 cttgttcgta gccgtgttct tctttcaacc aagctttgat tggcacaggg aatcctaatt
    11401 tcacacgatt cgaccattct tccggaagat gtttgttcgc agcttgtctg aaaatatctt
    11461 ttgtgttgtt ttgattcaat aaaaacttac ttggtatttg ttgagccaat ttcatgactt
    11521 cgatatccaa taaaggtact cggacttcca aagaacttgc catagaaagt ttatctgcct
    11581 ttaacaagat atcttttggc atccattgat gaagatcgac atattgcatc ttattgactt
    11641 catctttgat tccttctgtt ttctcgtaat gaacagtcat gatttcatcc acagatggtg
    11701 ctgtttgata ttttggtgtt aacacttctg atgcttctga ttcttcgaac actcgagcat
    11761 gaccgataaa atattctttt gcaggagcaa gtgattcata taaatggatc cgtccatgga
    11821 agtttttcat ttttccgatt ttacgtccta aattatagcg tgttcctttt ggtaattttt
    11881 tcaatccttg agcaatcaca cggatgaatt ttgaattcgt atggaatcca tacgtttggt
    11941 atcccgcaaa cagttcatcc gccccttctc cagattggac tacccgcaca ctttgtgaag
    12001 caagatttgc taaaaagtac aaaggtacgc aagaaggatt tgaatcaggt tcatctaagt
    12061 gatactggat caaagggaat gctttgaacg acatgtctcc gtcgatcact gctgctgtat
    12121 tatctaagtc caatagttcg gttagttttc tggcttcaat cgcttcatta taggttttat
    12181 catcaaaccc gattgagaaa gaatgatctg gtttcaatac agaggttaca taactggaat
    12241 caaccccgct ggataagaaa gaaccaactt ctacatcact gaccgtatgt gcttcaatag
    12301 aagcttgaac ggtttcgtcg attttttcga tccattcttg tcgggaatgc gtttcttttg
    12361 tttcaaaatc tgcatcccaa tattgctgaa tgtctatttt tccatcttta tacgtataat
    12421 aatggccttc aggcaaacga tagacatctt tgaagaatgt ttcgccgttt aatggagaat
    12481 attggaaagt catataaggt ttcaacgctt ctttgttcaa ttctttgtta aaatcaggat
    12541 gaggcagaaa acttttgatt tctgaaccaa acataaatgt tccgttcatt tctgcataat
    12601 aatatggttt gatcccaaag tggtctcttg caccgaataa ctcattcttt tcattatccc
    12661 aaatagcaaa agcaaacatt ccgcggatct tttgcaataa ttctgttccc cattcttcgt
    12721 aaccatgcaa aaggacttct gtatctgcat gtgtttgaaa aacgtggcca gctgcaatca
    12781 attcttctct caaaggctgg taattataga tttcgccatt aaaaataatg atctttgtcc
    12841 gatcttcatt gtaaataggc tgagtaccgc cctctaagtc aataatactt aatcttctga
    12901 atcctaaagc aacatgttta tcgatatatt ctcctgaact attaggtcca cggtgaacga
    12961 ttcgatccat cattgtatta ataattgttt ttttgttgtc cttgtcgtta acaaaaccta
    13021 caataccgca catttaactt tcacatccta atataaaatt actgtttatt tcattcatat
    13081 gcatcttatc atagaataaa tagcggacga atattttctc tcttacaatt tcgtcacgtg
    13141 aaaacaaaag atgaaagttt ctgtttttac agaaaataaa gtcccaatat ctaatttacc
    13201 atgttttctt ttttgaggct accttattct cttcgtgtta aaaaaatatt agtggatgct
    13261 atttccaaaa aaaccagcaa aaaaagacac gacctaaaga tcgtgt
//
LOCUS       DAFLWC010000080        12920 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.082, whole genome shotgun sequence.
ACCESSION   DAFLWC010000080 DAFLWC010000000
VERSION     DAFLWC010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12920)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12920
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.082"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            133..3660
                     /locus_tag="L1V17_002257"
     CDS             133..3660
                     /locus_tag="L1V17_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBN1237001.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="L1V17_002258"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="L1V17_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBN1237002.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="L1V17_002259"
     CDS             7448..7789
                     /locus_tag="L1V17_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1237003.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="L1V17_002260"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="L1V17_002260"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBN1237004.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /locus_tag="L1V17_002261"
     CDS             9146..11566
                     /locus_tag="L1V17_002261"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBN1237005.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="L1V17_002262"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="L1V17_002262"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBN1237006.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
BASE COUNT         4389 a         2244 c         2739 g         3548 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg agcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac tttacaaatt
//
LOCUS       DAFLWC010000081        12866 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.083, whole genome shotgun sequence.
ACCESSION   DAFLWC010000081 DAFLWC010000000
VERSION     DAFLWC010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12866
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.083"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..1118)
                     /locus_tag="L1V17_002263"
     CDS             complement(<1..1118)
                     /locus_tag="L1V17_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBN1237007.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLE"
     gene            complement(1240..1836)
                     /locus_tag="L1V17_002264"
     CDS             complement(1240..1836)
                     /locus_tag="L1V17_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBN1237008.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(2036..4678)
                     /gene="alaS"
                     /locus_tag="L1V17_002265"
     CDS             complement(2036..4678)
                     /gene="alaS"
                     /locus_tag="L1V17_002265"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBN1237009.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            5066..5497
                     /locus_tag="L1V17_002266"
     CDS             5066..5497
                     /locus_tag="L1V17_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1237010.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            complement(5542..6891)
                     /locus_tag="L1V17_002267"
     CDS             complement(5542..6891)
                     /locus_tag="L1V17_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBN1237011.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(6961..8124)
                     /locus_tag="L1V17_002268"
     CDS             complement(6961..8124)
                     /locus_tag="L1V17_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBN1237012.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            8253..8576
                     /locus_tag="L1V17_002269"
     CDS             8253..8576
                     /locus_tag="L1V17_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237013.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            complement(8759..10108)
                     /locus_tag="L1V17_002270"
     CDS             complement(8759..10108)
                     /locus_tag="L1V17_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1237014.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(10177..11130)
                     /locus_tag="L1V17_002271"
     CDS             complement(10177..11130)
                     /locus_tag="L1V17_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBN1237015.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            complement(11232..12422)
                     /locus_tag="L1V17_002272"
     CDS             complement(11232..12422)
                     /locus_tag="L1V17_002272"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HBN1237016.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
BASE COUNT         3694 a         2711 c         2223 g         4238 t
ORIGIN      
        1 atttccaatt ggtaatctcc gattttttct tctatttgac tacgtaagat tctttctagt
       61 tctgtatcaa caaactggaa tttctcaggg accactacat caaattgcag cgtttttcct
      121 tgatgaatta ctctaaaatc atgaatatta agccctgtac ctgtttcaag aagaatttgc
      181 tttaactgcc gcaagatatt atagtatttt tcgttatcaa caggcattgg atccaagtga
      241 cagacaagtt ccacatccaa agacttttta aagtcttttt ctatcagatc aataatctta
      301 tgagccacat tcaaattcat tgattcatct acttcgatgt ggactgatgc aaagcgttta
      361 ttgggtccat agttatgcac caataaatca tgatagccaa gtatatcatc gcaagcattt
      421 aaatgctctt ccatttcttc aatctctgct ggcgttgggc gacttcctaa tagttcgtat
      481 acaaaatttc gaagcatcgt caatccacta taaaggatat ataatgctaa agcaaaacct
      541 atatatccat caatacgcca tccagttacc cattcgattg ctgctgaaag caatacagcc
      601 agtgtagtaa agacatcatt ataactatct gttgctgtag ctctcaatgt ttcagaatca
      661 atggattgcg caataacctg atacattttg ccttgtgcaa atttcaaaaa gatggaaatg
      721 attaggacaa aaaagacgat gggtgttaaa gagacatttt ctggatggat gattttttca
      781 gcagaagact ctaaaaattg aaatcctaca taagtaatga tgatcgaaac aaataaccca
      841 ctgatatatt cgaagcgttc gtgtccataa ggatgttcct gatctgctgg ctttgcagca
      901 attttaaatc cgatcaaagt caatatggat gaagcagtat ctgatagact gttcactgca
      961 tcagccataa tggagacact tcctgaaaaa agcccgatca ttagcttaga gacaaacaag
     1021 atcagattcg taaccaatcc taagataccc gctagtactc ctttttttgt ccgctgttgc
     1081 ggtatttgtt tctttttttc ttcttgtttc ttagccaagt tttttacccc ttctagtttg
     1141 cttgttgctc aggtaaaaag atggagagga cgattgtttt cctctcctct cttccttttt
     1201 ctatctatcg tgcgtcctat tactattaaa agatggtcat tattctggtt tcaacggtgt
     1261 tgctgcaaat aacgcttttg ctagtaatgg tgttatgatt cccgcaccta ttgcttctgg
     1321 tatcccattg attgctgcaa cccctgctaa ggttttaaat aaaagagcag agtctacacc
     1381 ataggcatct gccgttgcac ctgtataaaa taatcccatg aatcctaaca ctaagactgt
     1441 attgaccaat gaacccagta cccctgcaaa ggctgagctg atcgttattg atttattttt
     1501 ttgataaatc cagtggaaaa ccaagcctgc tactaagcca acaagtactc tgggaactac
     1561 cgagataatc ggattcgtga acactaatgt atcaaatggc gttgttggca tggcataggc
     1621 acgaacaatt gtagcgattc cccaaaacaa gccaatcacc atgccatctt ttgggcctaa
     1681 tactactgca gcaataatta ctgtgatatg gataattgtt aaactaatga atcctaatgg
     1741 aataaacccc agccaaggaa ccatcgcttg tacgatgatg attgctaaca agatcgcacg
     1801 taagactagt cgaaaggtct tatttctact attcattttt tcaccccttt ttatttatac
     1861 taatcgtaaa aatttctgtc actttcgtca actaaagacc atccgaatcc gaccatttga
     1921 ttagatgcgc catccaattg aaaaaagtat gagggcaaga cttgtttgtc ttcgccccca
     1981 taatcatgtt tcgttcaatg tttgaacttt tgtttttctg tcaaacgtaa acgccctatt
     2041 gttgcgcaac ccattctttc gcagctttaa gtgcatctgg aataccagca ggatttttcc
     2101 cgccagcttg tgccatgtct ggacgtccac caccgccacc gcctactttc ggtgcgattg
     2161 ctttaatcaa gtcgccagct tttagtccag cttcatttga ttctttcgtc attgccgcta
     2221 gcagactgac ttttccttct tgttcgtttg ctaaaacaag aatatctgaa atattttttt
     2281 gtttccattg gtcagctaat tgacgcagct gattcatatc tttcactttt acttgtgctg
     2341 caatgattgt ttttccattg atcgtttctg gatctttgaa tacatcacca gcttgttgat
     2401 tcgctaactt gctagctaat tgttcatttt ccttttgtag ctctcttact tgctgttgca
     2461 attgttccgc ttttgaaaca acttctttca attgaggtga tttaacaatt gttgctactt
     2521 gttttagttg tttttcttct tcttcaagta gttcgtacgc ttctttactt gttacagcct
     2581 cgattcgtcg cacgcctgca ccaattcctg attcagaaac gattttgaag attccgatgt
     2641 tttctgtatt tgctacatgt gtgcctccgc acagttcgat tgaccagccg ccaatattta
     2701 ctactcgaac gtcatgtccg tatttttcac caaacaaagc cattgcaccc atgtttttgg
     2761 ctgtatcgat atctgtttca attgtttcaa ctgggatagc ttcccagatt ttttcgttga
     2821 cgattctttc catttcagct aattcatctg aagtgatttg accaaagtgg gtaaagtcga
     2881 atcgtaaatg tccaggagcg actaaagaac cagcttgatt tgcatgctcg ccaagtactt
     2941 ctttcaatgc cttgtgcagt agatgggttg ctgtatggtt tttgatgatc cgattgcgca
     3001 tcgattgatc gatcaataga tgataggttt gtccttcact cattggtgct tttacttcta
     3061 cggtgtgcat aaattgacca ttaggcgctt tttgaacatc tgtaacaact gctacgattt
     3121 cgcctacttc attcatgatc catccttgat ccgctacttg cccacccatt tctgcataga
     3181 aaggtgtttg atcaaagatc atttgagctt caccttctgc gacttcattc aaaagagact
     3241 cacctttaac gatgaccaat aattgactat ctgattcttg ttctgtgtat ccaatgaatt
     3301 tactttctac tttgatatct gtcaataaag cagattgtac ccccattgat ttttcagtac
     3361 tgcgggcaga gcgagcacgt tcgcgttgtg catccatttc tttttcaaaa ccagcatgat
     3421 caactttcag tccttcatct tctgccacct cttccgttaa ttctaccggg aagccatatg
     3481 tgtcgtatag tttgaagatg tcttttcctg ctagagtcgt cccgttttcg ttttttactt
     3541 cttggatcac ttgatttaag atttccaaac cttcattgat tgtttcattg aaacgttctt
     3601 cttctgtacg gataactttt tcaataaatt ctttttgttg aagtacttca ggataataac
     3661 ttaccatgat ttccccaaca acagggacta aacgatataa gaatgcttgt tcaataccta
     3721 attttttccc atgcatgaca gcacgacgaa gcaaacggcg taagacatac cctctccctt
     3781 cattcgatgg caatgcaccg tcgccaatag caaatgaaag ggcgcgaata tgatctgcga
     3841 ttactttgta agaaatatct gttactgggt tttcaccata ttttacttgt ttgcttagct
     3901 tttctacggc gtggataata ggcataaaca agtctgtctc aaagttcgtt gacgcatctt
     3961 gaacgattga gaccatgcgt tccaatccca tccccgtatc aatgttttta tgaggaagtg
     4021 gttcaaatgt gttatcaggc ttatggttga attctgaaaa tactaagttc cagatttcta
     4081 aataacgttc attttctcct cctggatagt tttcaggatc gtcttctgct aaatcgttat
     4141 aagcttctcc acggtcatag aaaatttccg tatccggacc acatgggcct gcaccgatat
     4201 cccagaagtt gtcttctaca tcaataatgt gatctagtgg caggccaact tcttcatgcc
     4261 agatgcgttt tgcttctgta tcttttggat aaactgttac ataaagtttt tctggatcga
     4321 atgccatcca ttttggatca gtcaaaaatt cccatgccca gtggatggct tcatttttga
     4381 aatagtcacc aatcgaaaaa ttacccagca tctcaaacat cgtatggtgc cgtgctgttt
     4441 taccgacatt ttcgatatca tttgttcgaa tagatttttg ggcatttgtg attcttggat
     4501 tttctggcac aactgaacca tcaaaatatt ttttcaatgt tgcaacacca gagttgatcc
     4561 acaataaggt tggatcgttc acggggatca aagacgcact aggttcaatc gtatgtcctt
     4621 tagattggaa gaaatcaaga aacatttgtc gaacttgtgc actacttaat tgtttcatgt
     4681 cattacctgc tttctataaa ttaaatacaa aaaaacacca tcacagccaa ggacgaaaac
     4741 tcgcggtacc accttgattg caatgatgtg taatcattac ctcttaaact cgataacgct
     4801 gagctgcgtc ggtatttcta ccaaaataga aaaagggagc aatttgatta gtgactattc
     4861 ttttttcagc caagaaagaa ttttctgtga gtcttaaaaa acaaatcata tccttttcgt
     4921 acttaattag tatacgcatt ctattgatca ctgtcaatat ctcaattttt attttcattt
     4981 ccttttggtc atactccacg atttttggta cgataagaat aaaggaatca atacatctct
     5041 gctattcatg acaaggagga atatgatgaa aaaaatagtt ggagcggatg aatggatacg
     5101 cgcagctagc tgctttttga gatatcaagt ttttgtatta gaacaaggga ttcctgcaga
     5161 actagaattc gacggaaaag atatcccgca acaaacctat tatctatttc ttgatcaaaa
     5221 aagaccagta gctactttgc gttatgaaaa gaaaacacct acttgcttca agccggaacg
     5281 attttgcgta gcaaaagaat accgaggaaa agggttaggc ggtcagttgc ttgaagctgc
     5341 tgaaaaacgg gcggtttcag aaggttgtca gactagttat gtagtagctg aaatgacggc
     5401 tgtagatttt tatgaaaaac aagggtatca tacttgcaca gaacctttta ttgaagatga
     5461 agtactttgt atcggaatga aaaaaagtct agcttaaaaa caagagattg tgacacgcct
     5521 tttgtcacaa cctcttgttt tttatttatg tgaatttttc ttatttttac gagcagtacg
     5581 gctttgctgt ctgcgttcga ttttgcgttc ttttttattt ttttctgcaa ttgcccaatc
     5641 gatttttttc ttataaccag gcttgatctt tttctttttc ttcttcacaa gaccaatcag
     5701 cgtgggatct aatacatctt ttgatttttc tcgtttggca cgtctattac gatcgtatgt
     5761 tttgacgatt tccccgtttt tgatttcttt tggttcaaat gagacgccca atttttctat
     5821 cgcatcaatg gcttgctcat catttggcga atataacgta atggccgttc cttttaagcc
     5881 attacgtcca gtacgtccga cacgatggat aaagaagtct agatcttctg gaatttctgc
     5941 attaataaca tgagagacac cttcgatatc gatccctcta gcagctaaat cagtcgctac
     6001 aacatattga tactccagat tctgtacttg tcgcatcact cgttttctct ctcttggggt
     6061 gatgtctcca tgaatctttg ctactttcaa gccttggttt ttcaagtaat cggcaatttc
     6121 atccacatgc tgttttgtat tggcaaatac gattgctaaa taaggatgac caattgtcag
     6181 cagttgataa atcatttgat tctcatcttt accttttgtt gaaatcagcc aattttcaat
     6241 gtcttcagaa ataactgctt ttggtttgat ttcttcaatg attggatttt ccatgtattt
     6301 tcgtaagaat ggacgaagtt tttctggaat agtggcagaa aaaactaaaa actgcagctt
     6361 ttctggtaat cgacttgcaa tttggtctac ttcatttaaa aaacccatat ccaatgtcat
     6421 atccgcttca tcgacaacaa atgcaaatgc ggtgtgaatc ttcagcgctt gttcattcat
     6481 catgtctaat attctaccag gcgtgcctac tacaacctgt ggctgttggt gatgcagacg
     6541 atttaattga cgctgtttgt ctgtaccgcc gacaaaattc gagacacgga tctccggtgt
     6601 agaaaattta gcgatttgtg tagctgcttc atagatctgt gcagctagtt ccctacttgg
     6661 agctgtaata acaacttgta cttcctcttt ttctgcattg attttttcaa acaaaggcaa
     6721 caaaaacgta tgtgtttttc ctgtaccagt ttgagattgc ccaatgatat tttttccttt
     6781 tgcaattaaa ggaatcaaac gttcctggac ctctgtgggc tgtttgaagc cctttgcggt
     6841 taacgcttca ttgataaacg gtttgaagcg gaatatatca aaattattca ttcgtgcacc
     6901 tcttctcttt aaattatcac gactttggca ttataacaca gacaaagcgt ttttgctcag
     6961 ctaatttcga gaatcatcat cctttgtttg gccaatcgtg ctaacagtat atgtgtgact
     7021 agctttttca taaaacagaa tccgtttttt tctcaaaaat gatagcaaga tatttaaaat
     7081 aaaaatacct tgtagtaaca agacaccgag agaaatgaat actgcactca tctgcaacac
     7141 cgtattcgtt gtcgaattca tgatttgctg aagcaactgc cccaaccagc ttaaaccata
     7201 aaaaagaaag tacagatacc cgtagcggat catcaatgct tttaaagaaa ttcgttcgcg
     7261 gtcttcttcc accaaacgga tacgcacaat ttttttgcca agtgtccatc cattggttat
     7321 aaacggtaca atcataaagt atacccctac ttctaataaa agccaccaga tatgagaagt
     7381 aactgcccct gaatcgaacg caattttaaa gaaaatcgcc gctaccaaat taataagaga
     7441 taaaaatgtc cagtcgatca aataagcgac caagcgtcga gtcaatgaga cagtctttcc
     7501 tttttcataa gaaagttcat ccattcgtct tcttgtagga agcataaatg taaataacgg
     7561 cgtaacgaca aaaccaatga ttccacccaa tgtatttgtc actaaatcat tcacatcaaa
     7621 taagcggtat ggtcttgggt agataaaata aagtccactt agctgcgtca attcaaaaaa
     7681 tagagaaagg cagaaactag caatcatcgt tttcataaaa gaaagccgga aataatatct
     7741 taaataaatg ccaaacggta tgagtaataa aacattaaaa gctggttcca aaaatacact
     7801 ctgcttcatt gccggcaggt aggtactagg ttcagacaag accaataccg tgttgtctct
     7861 gaaatgttgc catgaagcaa ataaatgcag ctccatcttt ggccctgtca tttgggcaac
     7921 cgtctccttt gccggaagtg gtaagatcac caaaaaatac gcacacaata aataaaaaac
     7981 gaaagaatac aaaataactg cccttgttac tagaaatgtt ccatactttc gatattcata
     8041 aataaaaaaa acagatgaga tcgctaaggc taaaaatgga aaaacaatca gcgcaaaacg
     8101 aatcggttcg atataacttg ccatatgact cctccttgat tctttgtatc tctcttatct
     8161 tagcagtcct ttgctgtttc aagcaagtaa cgaggctatt atttctcatt tctttcaaag
     8221 taaagtaaga taaacacaaa gggggtgtcg agatgctgaa tatgtacttt gtttttggcg
     8281 tacctatttt tttactgttc ctttatgcta cgatcgctta tgtaagaaaa agaactacaa
     8341 ttcattattt aggatttatt ctcctgatta tttcgggttt catgctagtc ttcaatcttc
     8401 agacttggca gcaagcactt cttgaaatgg ataaaatgac tccacatgct ttgtctaaag
     8461 tgcttggcta ccctgtctat ctgatttggc ttcccatttt catttctggt tgcttggttt
     8521 tattaaatat ttatcgcggc gtacgccgaa tagttcagtt acgcaaatca aagtaaaaga
     8581 cagaaatcgg ttgagcccga tttctgtctt ttactttgct atttcatcgt agacaaaacg
     8641 acatttacgt gatcaaaatt aacgagtact tttgacattt cttccacgta ctcctcattt
     8701 aaataaaata ttttgtttgg cagagaagtg cagttctaat aaaattcgaa tgttttagct
     8761 atctacgttt taaatagaga taaatcggga taccagcaag tgtcaatact atccccatcg
     8821 aagctaaaaa ggtctgagtg ataagcgtgc ttgatacgat aaaagtccct ccaatgattg
     8881 ctactagtgg aataaacgga tacattggaa ctttgtatgg tcgaaacaaa tcaggttctt
     8941 ttttacgaag aagaatgaca ccaacaaaga ccatcgtata aaaaatccaa atgacaaaga
     9001 tcagcatatc cgttagtgta tcaaaaccac cgatcatcat catgccaata gcgatgacta
     9061 gctctaagat acctgcggct acaggaactt tagttttatc atgaagttta gcaaagagct
     9121 tgctaaaagg caggttgttt tcttttgcca taacataagg gagacgcatt ccagtaaggg
     9181 tatagccatt gatggttcca taaacagaaa tcaagatacc aactgtgacc agtcttccac
     9241 cgaagccgcc aaaaatcatt tttgcaacgt cacttgccgc attgctgttt cctgcgactc
     9301 cgtcgataga tgcggttctt aagaacaccg catttactaa taaataaacg atcatgattc
     9361 cgatgattcc taaagaaatt gcttttggca aatctttcgc cggctttttc aattctcccg
     9421 aaatatttcc tacgtgtatc caaccgtcgt atgcgaacat cgttgctagc aagcccgctc
     9481 ccaaggctga gaaaaatgaa agattttctc ctgcttggat cggaaacagt tggaagtcta
     9541 ctccttcttg tcggaacaaa ccgaaaatga cgatcacaaa caaaggaata agcttgcaga
     9601 caagcgtaat cgactgaaaa gcccctccag ctttagaacc taaaaaattg atcaacagga
     9661 tcgatacagc agctgtaaca gctacgggaa caatcattga ctgggaaaga ccaaatagat
     9721 tgacgaactg tgtaccgaaa atgatcgaca aggctgctac atttgctgga aaataaatca
     9781 cgacttgcgc ccagcccaat aaaaaagctg ctgtatttcc gtaaatccgt tcgatatatt
     9841 taatcatccc tcctgtttct ggaatagcag ctgccagttc agctcctgtt agtcctgcac
     9901 agacagaaat cataccaccg agaaaccaag aaaacatatg caaactggcg gatcctgtaa
     9961 cttctgctac gcttgcggct ttaaaaaata cccctgcacc gatcactgtg cccataacag
    10021 tcgataaagc agtaaaaaat cccatcgtac gttttaattc attttctatt tttacttctt
    10081 ttactggcgt ggcttgatat tcttccatcc cttgtcccct ttcataccat agccaatccc
    10141 aaaagtataa aaaacttttt ggatgtggtt cttgttttat accgtctcta ccaatttttc
    10201 tttcagtttt tccaacatat cctttgtcat cacatctaag tcgtatttcg gcgaaaagcc
    10261 ccattcctct tgcgcacaag aaacatctag tgaatttggc caagattctg ctattgactg
    10321 acgtacagga tccacatcat aatccatttc aaaatctggt atgatttttt gaatagatgc
    10381 tttgatctct tccgggtcaa aagacatcgc cgatatattg aaggcatttc gatgaaccaa
    10441 tcgatcagga tctgcattca tgagttttat aatggcatcg atcgcatctg gcatatacat
    10501 catatccatt gatgtacctt gatcaatgaa actagtgtac tttccttctt tgattgctga
    10561 ataataaata tcgactgcgt agtctgtcgt accgcctcct ggcaaggttg cataagaaat
    10621 caatccaggg aaacggacac cacgagtatc tacgccatat ttcacataat aataatcaca
    10681 tagtagttct ccagctacct tcgttacccc atacatggtt gtaggacgct gaagagtatc
    10741 ttgtggggta tgatcttttg gagtatttgg accaaacgcg ccgattgaac ttggcgtaaa
    10801 aaatttcagc tggaattctc tagcgacttc caatgcattg accagcccag tcacgttcaa
    10861 attccaggct aattgtggtt ttgcttctgc aacagctgac aaaagagcag ccaaatgaat
    10921 caatgtgtcc acttgatatt gttctgctat gctgcgcatt ttttcgtaat ccattacatc
    10981 taggatctca aagatatcgt ttttctcaat gacttcaggc atgcgtatat ctgtcgcaat
    11041 gacattttca ctgcctagtt cttgacgtag ccgtgtgatc aactctgaac caatttgtcc
    11101 taaacatcct gtcaccaata cttttttcat gatgatcctc cctgatcttt tttactacta
    11161 tcttcagatg attaacaata tatgcgtgaa catgttctct aattttaaat agacgaaaaa
    11221 actaaattta gttaaataat ttccatttct tttcctattt tttgataaac tgctactgct
    11281 tcatcaagca tttccctcgt atgttccgca gtcggcatat ttctgatcct gcctgtccca
    11341 agaggcacag ttggataaac gattggttta gcataaatcc catgttcgat cagcttctta
    11401 gagaaagtct gagtcacttt ttcgtctccc aaaatgactg gagtaatagg tgtttcagac
    11461 ataccgatgt tatagcctac ttttttcaat tcttctttaa aataattagc attttcccaa
    11521 actttttcga caagttccgg atgttcttgc atcaaagtaa tcgaagccaa tgcagctgca
    11581 gctgcacctg gagttagcga agtagaaaat aggaatggcc gacttctagc tttcaaccag
    11641 tcgattagtg ttttcgatcc agctacataa cccccaacaa cacctatagc tttcgataac
    11701 gtgcccattt gcatatcgat tttgtcgctt aatccaaaat gcttgacggt tcctgcacct
    11761 tttccagtta cgcctgagcc gtgcgcatca tcgacgtagg tgatcagtcc atatttttca
    11821 acaatcggaa taatttccgg caatcgtgca atgtctccat ccatggagaa aacaccatct
    11881 gtgatataca tgattttttt atatttctta ctttctatcg cttcctttgc ttttttctca
    11941 aggtctttca tatcttgatg tttaattcgg atgatttttg ctccggataa gcggcaaccg
    12001 tcaataatag atgcatggtt taattcatcc gataagatag catcttcttt tgtcattact
    12061 gcagagatag cgcccatatt gcagttgaat ccagattgaa aggcgattgc tgcttctgtc
    12121 cctttgaatt ctgcgatttt ttcttctaat tgctgatgga ttttcagcga accattgatc
    12181 gttcggactg ctcctgctcc tacaccataa gtttcggttg cttcaataca tgcttttttc
    12241 aattcttcgc gattggcaaa tccaagataa ttgttggatg ctagattgat catctttttt
    12301 ccgtctacga tgatacaagc accattttca ctttctagta tgtcgatcgt attgtataac
    12361 cccttttctt tcagttgatc caattctttc tctaaataca ttgttagttc tttggaagac
    12421 attgtctcca cctccatatt catctgtctt gcagaacata ccaaacatat atcgtgtcat
    12481 tcatctacaa agcaagtatg ctatattttt gataacgctt acactgatta tgagaattat
    12541 ttaaccacat tttttattta cagtatcttt ttactttcaa atgacttata tagtatgaac
    12601 aattaccttt tagataatga tctattttac tctacctggg cagataaata taacacaacc
    12661 attgatagaa gccctttcgt taaaatcaat tgtattctga atatttaatt tatttattgc
    12721 atagaccaat aaaaatacat aaaatttcca tcttcgttta tcagcaattt ttaattttac
    12781 tctctgaata tttcttaaaa gttttacttg ttgaattcga aaaaaggact gtgacaaaag
    12841 tcttgtcaca gtcctattct tccgaa
//
LOCUS       DAFLWC010000082        12741 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.084, whole genome shotgun sequence.
ACCESSION   DAFLWC010000082 DAFLWC010000000
VERSION     DAFLWC010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12741
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.084"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            51..899
                     /locus_tag="L1V17_002273"
     CDS             51..899
                     /locus_tag="L1V17_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBN1237017.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            1545..1751
                     /locus_tag="L1V17_002274"
     CDS             1545..1751
                     /locus_tag="L1V17_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HBN1237018.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(1953..2954)
                     /locus_tag="L1V17_002275"
     CDS             complement(1953..2954)
                     /locus_tag="L1V17_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1237019.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(2959..4872)
                     /locus_tag="L1V17_002276"
     CDS             complement(2959..4872)
                     /locus_tag="L1V17_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBN1237020.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            complement(5040..5546)
                     /locus_tag="L1V17_002277"
     CDS             complement(5040..5546)
                     /locus_tag="L1V17_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBN1237021.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            5706..6146
                     /locus_tag="L1V17_002278"
     CDS             5706..6146
                     /locus_tag="L1V17_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBN1237022.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            complement(6172..7329)
                     /locus_tag="L1V17_002279"
     CDS             complement(6172..7329)
                     /locus_tag="L1V17_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1237023.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(7332..7688)
                     /locus_tag="L1V17_002280"
     CDS             complement(7332..7688)
                     /locus_tag="L1V17_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237024.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            complement(7986..8960)
                     /gene="sgrA"
                     /locus_tag="L1V17_002281"
     CDS             complement(7986..8960)
                     /gene="sgrA"
                     /locus_tag="L1V17_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HBN1237025.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSEISTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            complement(9156..9995)
                     /locus_tag="L1V17_002282"
     CDS             complement(9156..9995)
                     /locus_tag="L1V17_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBN1237026.1"
                     /translation="MIRIIRLIGSVLIVFVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            10180..11067
                     /locus_tag="L1V17_002283"
     CDS             10180..11067
                     /locus_tag="L1V17_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBN1237027.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            complement(11661..12355)
                     /locus_tag="L1V17_002284"
                     /pseudo
     CDS             complement(11661..12355)
                     /locus_tag="L1V17_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
     gene            complement(12339..12737)
                     /locus_tag="L1V17_002285"
     CDS             complement(12339..12737)
                     /locus_tag="L1V17_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBN1237028.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
BASE COUNT         3853 a         2501 c         1930 g         4457 t
ORIGIN      
        1 taatgagaac ggaaaaaatg ataatcttat tatgaaaatg aggaattctc atgagcgtct
       61 ccataagact acaaatcaaa acaatgtaca acgacttcag cccaaaagaa caggctatcg
      121 ccgattatat tttagaaaat ccaagcaaag taagtcatag tcctattagc aatttagcaa
      181 gtgaactggg cattgctgac tctacttttt ttcaatttac aaaaaaactt ggttataatg
      241 gatttaaaga ttttaaaatg gccatgttga tccaagaaaa tgatctatct gctatttcta
      301 tccacgaaaa tattcagaaa acagatactg agctcactat ggcgcaaaag gtgttcgagt
      361 ctagtatttc aactttaaat gacacaaaaa agttgttaca acaaaaggat ctaaaaaaag
      421 cggctactat tatcaatgaa tctaaacgtg tctatttttt cggtgttggc ggttcagaga
      481 ttgtagcaac tgacgcttat cataaatttt tgcgttcccc tatcgcaact tctcacagca
      541 cggattacca tattcaattg atggaagctt ctttattgac ggaaaaagac tgtgctgttt
      601 tgatttctca cacagggcaa tcaaaagaaa caatccatat tgctgaaacc gtaagaaaaa
      661 ctggagcaaa aacaatcgtt attactagcc aagctaattc ttcccttgct aaacttggcg
      721 atgtcgtttt tatttctatt tctgaagaaa cagaattccg atctgaagct ttagcttccc
      781 gtatttctca actaagcatt ttggactctc tatatgtgat tttgatgttt tacaacgaaa
      841 aagaatcacg tcgttctatc gctaaagttc gacatactat ttctgaaatc aaagaatagc
      901 accataacag aaaaagcgaa aaatccataa aacaaaaaaa gccactacca aatatttggt
      961 agtggctttt ttggttctgc aagggtggta cagaacatca atagtcggtg ggttagaacg
     1021 tatgtcatcg catctttgga gaaggttgta ttggtattat tcgagttact tgttagatgc
     1081 gataacaaag ttagtataca gtagtaaaaa atttatcttt tctttttttt attatttttg
     1141 tttcttattt tctaaaaaat taaaaaaaat tttggtgaat taagtatttc cttgataaca
     1201 ctggcttttg gcctcatttt aggttatcat ttgtaatttt atttcacagt tgatatgatt
     1261 gttatgtaaa ataaaaaagt ttaggataca tcgaattttt ggggaaattc ttttgggggt
     1321 atcctaaatc ttttctatta tattcccata ttttctatta ttggtctaga cgtatgatgg
     1381 taaactttgt acctatctga ttgctgaatc attaattgct tatcattagc catctttgtt
     1441 tcaagttcgc tagatgatca ttttattcac atcctaacaa acttgtcaca tttatagatt
     1501 cttaatctat ttatcataca attataaaaa aggaggtgct gcttatgaaa gctatccata
     1561 tttctttgct ttttttcgct agtgcattga ttttatttgc tattcatctt tgttcccagc
     1621 cttatatcaa taacaacgga atattagtgg aaccagcatt cttttgctta ccactcggct
     1681 ttttgtccct tcttgcctcc gcaggcttcg gatttgttgc tttttttaaa cgatcaaaac
     1741 aacaaatctg acttataaaa tttacgtaaa agagatcgtg acaataatcg tgtgatattc
     1801 ccaaatttcg aataaaaggt gccccttgcc atctctaact cctcagtcac aagttacaat
     1861 attcataaac catgaaaagc ttgtttattg aaattgctcc ttgtgacttg gagctaagtg
     1921 acagattaca acctcttttg catcataaga ctttactcct tgaaaaacat tactaacttt
     1981 tgatatgttt cttgcgcttg tttattgctg aaatcaaact gatattcatg gttcaaaaca
     2041 gcatttttct ccgcataatc tacttttgtg actttcaccc ccgctttctc aaatacagaa
     2101 gttacttctt ccatttgttt cgtaaacgta tttgtatttc catccgttaa gaatgtgttt
     2161 tgcgtccaac gatccgcatg tctgaccaag gctaaacttt tgaccttctc tgattgttca
     2221 aagtccttat tatcaaagta agcccatcca catttttcat aaagaaagct agagatttta
     2281 tcacttactt gagtaagtgc agaaggatcc aacagaccag acaaagaaat aaacttcgta
     2341 atctgcttgt tctccaaagt cggatcaaga tgatcagctt ttttaatttc ttcattttga
     2401 agtgctaaca aatattctcc actaatttgt gcacctgccg aatttccacc aatcgaaata
     2461 ttcgaccaat ctgcttgatc ttttatctct tttttagctg cttgaatggc ttcgttcaat
     2521 tggataactg gtgtaggatg ttttgcttcc ggtgatcgtt cataatctat atttacgatg
     2581 atttgctgcg tgtctgaaca tagatattcc aaataatcac gacaatcatt tttatcccct
     2641 cctacatatg cgcctccatg catccagaaa agaatcggta attttttctt ttccactttc
     2701 ggtgtgtaga tatccatatt attatttttg tactttgaag gataggatat ttcttttttt
     2761 atatcgattt gttcgatttt ttgctggaaa tcatctggtc gggcatatac ttgttctttt
     2821 tcacttgtgt caaattgttt tctaacaagc aagctaatcg gctttggtgt gatttgatta
     2881 atcaaaaata cagtgactaa aataactacg atgataactg gtactgcaat cactattcgc
     2941 ttgaaccatt tcattcattt accctctctt tcttcgccaa atccatgtga taatcgtgct
     3001 aacagataaa aatccacctg aataaatgag aagcgaatgt ttcttttctc cagttttcgg
     3061 caacattctt ttttttgcat ctgtcttttt ttgtactttc actgtcatct gaatcggttg
     3121 cgtatcatca cttgattgat cctctcgagg ttcattcttt cccttattgt ctgcattctc
     3181 tgtcggatct tgcttttttg gtggagctac tgggattttt ttgtaataga aaataatagt
     3241 tggtatcgtc tcattaaaaa tcccttcagt cggtccttca acatttgcta attcgtatcc
     3301 ttcgaatgtc ttttgctctg tcatataatt ttctccataa gctccgtaaa gctggatttc
     3361 gtcctggtct ttgagtagac ttttattgtt ttcatccaca tactttacgt ttatctgatc
     3421 atggaacact actttcaaaa agtccgttac atgtttcgtg taggcagcat ggtcaacttc
     3481 ctgtgccttt ccatgccctg ctccttctac taataaaaga tctttatacc ctcctgataa
     3541 ctcatataat ttttgcgcgt tagacacagg tactacatca tctgctgttc catggataat
     3601 caatttaggc aatgaatctg acattccaat cgtaggtaga gcagcttttg tatccaaatg
     3661 catctcctga tcaaaatagt attgtttcaa aaggcccata aataaatctt catgctcttg
     3721 atccccaatg atgtctaact gattttttat ggcatccggt agtgcggggg ctactgtctg
     3781 gctgtacgta aaacgtagtt gttcatcaat tgatgcaaat ccgcaatttt caataattcc
     3841 tttgacattg acaggaatat ctttcgctaa tacagacatc atcgtagctg ctcccatcga
     3901 accaccataa agtaaaatct tttgagatgg ccgctctcga acttcttgat ttatccagta
     3961 aaggacgtca tctgactcat attgtccata ggtcacataa tcgcctccgc tattaccagt
     4021 cgctctggaa tcaacaaata ataaattata cccggcctta taaaaatcat tgtattcttc
     4081 tgtaacgatc ccgttattcc aattccctcg aaatccgcca tggatcatga ctgttttatc
     4141 tgaaccttga tcgacataat atgcatatac atccatcatt ttgccatctt gtttgtttag
     4201 tacagtttga tgaagttgtt ttgtatttgg atagaagcct gtgttttctg taggcgttgt
     4261 cccatcatct gtacctccaa gcatcgacat caacacactg ttttttgcaa aagcgatatc
     4321 gtacaataga taagtagcaa tcagatgttt gataatctct ttatctacac cataatcatt
     4381 aacagcaagc tcagtgacta ataactctat taattttgac ttgatgtctt ctgttggtcc
     4441 attaagtatt tctgtcatct gtttaccgaa gtaattcaaa tattctttac cattgaaatt
     4501 ttcaccttta ccgatatcat cattttctgt cccattctct ttgtcactta ctttagcaga
     4561 agaggattcg tcgtttgaca tttttgtagc tgttgcttct tctgtttgtt ggttatctgt
     4621 ggtagcggtc gtttcttgat ctgtgctagt aacagatgtc tcaaccgttg tttcagtatt
     4681 tgtttctgtt tgtgaagtac tcgatttcgt ttcatttcca gcatcagtag tttctgtggt
     4741 ttctacctcc cgagattccg attcggaaga aatgctctct ccatatactg tccattgcgg
     4801 gacgcttgta cttacagcaa ataagatgac caacgctccc tttaatactt gttttgttct
     4861 caagctattc actccttttt atgtttctag gagaattata tgtaaacgca aacatttttt
     4921 atacaaaaaa taaatggttt atcccataaa aatagaacag gattattttc tcattttacg
     4981 taataaagca gaatggataa accagtatcc attctgcttt ttttaaacga agaaacaact
     5041 tattgctcca aaaatgtcag aaatcgttta tcccaaattt tctcgtaaaa agcgattgtt
     5101 tcctttgctt tcataaaagg attatcataa gttgtcgttg ctcctctaca catcataagc
     5161 tggtatccta atccatgagc aaacttcaca gtcgtatcta tacaatactc tgcttgtgcc
     5221 ccacataatt cgatcgaatg acagtccaat tcagttaata aaacactcaa attagtctta
     5281 taaaatgaat tcgcatgggt ttttctcaca aaataactgt gctcaggaat agataattcc
     5341 gacaatagct cccatggttt tgtttgtggc actaattgag catcttcgtg ttgaacgaaa
     5401 ataactggtt tcccaatcgt ttcgtatgtt ttgattcttt tattcactaa tgctgtcact
     5461 gtttctaatt cgtgtatcgg cgaagaatca aaacataccc ctttttgtaa atcgatcact
     5521 actattgcgt cggctgtgtt tgacatactt gtgccttctt tcttttttct tgatttaata
     5581 gtatttctta tctagctagt tccattatac gtgacaacat tttcttattt tacacctcta
     5641 aatggcactt ttcgactatt tcttcatgtt attatttcat aaatacttag ctattggagg
     5701 aatgtatgat gattaaattg tatacaggtt ctggctgctc gtcttcaaga cgcgcaaaac
     5761 gttggcttat cgtccatgat ataccgttta tcgaacagaa cttaattcgt caaccactaa
     5821 ccaaaaatga atttatccac ttactaaaat tgacaaacaa cggcgtgacc gaaatgctct
     5881 ctactcattc tattagttat aaaaatcttg ttcacagaat agatgaactc agtttgagtg
     5941 aactatatat tgagattcgt acatcccctt ctttattgaa aaaaccgatt atctacgacc
     6001 aatctgcaaa acttttgact ggatttagcg aagataaaat caggatgttc ctttctaaaa
     6061 ctaaaagaaa gcaagagctc aacgaactct tgctttctgg tcatcttgtc gattttaaag
     6121 aaaataatct ttttgcaatg tcttaatttt ggcataaaca atctgctttt cttaattaac
     6181 gaaatccaat ttttccaata tggatctatt tttctcattc ctgattttta tgatttcagc
     6241 tttcagacgc gcccaatcat tttttgtagg ttgtccattc cagtaaaata tctgtgtatt
     6301 cgtttgatca tatgcctttt tgtcgatagg ataatcgcta atgacaatat caggtaactg
     6361 atcagcggat gcactatatt ttattgggcg ttcagtcata gataatatcc ttttctttgc
     6421 ccataattcc tgtgttttac catactttga ttgaatatag aatatgacag gttgttcgtg
     6481 ttttataaaa atatccctga ctaacataca gtattgaaaa atcaaccgtc tgttcttttc
     6541 ataataagta ttaagctctg gaattctgcg agctacccca ctaaaaaact gttgcatgat
     6601 tggatacatc actggaaata tatgctgaaa atctctgtct tctgctgatt ttccaaaagc
     6661 atccaccttc ttttttgtcc caaaaaccct tgaatacaaa tggatcattg ccaaattgac
     6721 atatagataa tttttttctg aagttgtaaa acaaatcttg aagttttttt caaaattttc
     6781 tacaatagac gattcaatcc agccccaact ttcttgtact ttatctggag tatccaacaa
     6841 atcttcttcc aaataggtgt tcattacacc aaacataaaa taaaggtaag cttgctctgt
     6901 tggagtgatg tgattcatcg accagaagtt tgcttcaaaa aaaggctcta gtatgtaatg
     6961 cgtaaactct tcttttgtta tcaatggatg cacaaatttg ttcatctctt ctgggacata
     7021 cgtaatcgag tggccttgtt tcattcgttg caacgaaatt cttagtaggc tgatccattt
     7081 ctttctatct atactacgcg tatatggcgc atgtttcgca aatttttcta atagttgacg
     7141 tttatttttt atacttgata atatatcaga atgattttcg tcgaatgact gccaatacat
     7201 caagtgaaaa aagtatcgga tacggtattc ttctccttct atcggattac cttttttcaa
     7261 gctgcaagat aaatgatagt ttttcaaaat agtattaagt tctcttaatt ttctttgaat
     7321 cgtacgcaaa cttatataat tttttgacta agattttcta aggattgata agtacctttg
     7381 taaagtgaat ccagtaaaat ataaccaatc gttccctcta aaagtataga ataaacttta
     7441 ctcagtaaaa actgagaaga aaactcgact tttatcatct tgttttctga aagaaaagat
     7501 aatttatatt ctggatacct ttcgcaaaac gattctgctt gttgaatcac cgaattcatc
     7561 ttagccaggg tgtagtttag atctaaagcg atatccttca ccacatataa tttctcgtct
     7621 ctttcataac aatagttcaa aaattgatat acttgccttt cattgatatc aataaattct
     7681 tcaaacaaag tacatactcc tttttatcta ttatttagac ttattccgac agctacatga
     7741 ataacgtaca aatagattcg ttactgattt ttcagagata ctaccatgcg cagtgtgcat
     7801 tgtcaattat tcttgctctt attttccatt tgtgttcctg ttatttcctg tttctcaaat
     7861 atgttagtaa acaaaaatag atctggcaaa gctacaactt cgccaggcaa tacagcactc
     7921 tcgaatgaaa tattcactca aaaatctatc gttttattca attttagatc tgttgctttt
     7981 attctttatt tcactcgatg gaagagagaa cgaaaatagc ttgctcctac aatcaaaatg
     8041 agtaacacac ccatccatgt aattagcttg ttcaaggttc tactaccagt ttctggtaaa
     8101 tcgctttttc tattatctgt ttctttcgct ttttcttgat gatcaattcc acgagaaaca
     8161 aaatcaggct gttttagcac actttttagg ttgctccctg catttctctt ttgttcctta
     8221 gttggtatga taggtaccaa atcaagttca ttatttactt ttcctgtgct gctttcgctg
     8281 ctcgtgcttc ctgtgctact ctcactactc atgcttcctg tgctactttc actactcgta
     8341 ctctccgtac tgctttcgct gctcgtgctt cctgtgctac tttcactact cgtactctcc
     8401 gtactgcttt cgctgctcgt gttttctgtg ctaatttcac tgctcgtact ctctgtactg
     8461 ctttcaccgc tcgtgttttc tgtactgctt tcactacttg tgctatccgt actgcttggc
     8521 ggtccaacaa ctgtccaact gcttggtttc aaattctccg tgatcgtcat ctgtccatca
     8581 taaaaaacaa tcaaatcaac tttatcttta ctcttgatct catcaatcga tagttctgca
     8641 gaaatcatta ttgtatactc aataccagcg gtccattgta cgtcttttaa ataaacttcc
     8701 ccaataactt tttctgaact tccattacca tcccaaccat atgttagaac agcatgtaca
     8761 tcactagcat tcacgctttt gtttggtttg actggaatag taatgacttg ttgtgtcatg
     8821 tcataaacaa tccgatcagt tttcacagta aatgaaagat tctcatttgc ccgttcattt
     8881 gcagaagtac tgattccaat cattgctgca attatactca gcccaagaat aacaaataat
     8941 acggtcgctg ttttcttcat ttctatcact ctccatataa ttaccttcta tttgataaag
     9001 gaattatata aaatgaaaat gatgagaaca cgacagtcag ttgtgaaaat ctaacaaaag
     9061 atgtcgtgta ttcgcttgaa tttgtttact ttttcgttta atcaatgaca gacttaaaaa
     9121 agcaagaccg atatcagcct tgctttcttc atcttttatt gataaacagc agtgtatttc
     9181 ttcatccgct ttgttttata tgcatagagt aacaaaccaa caatcaagac taacaagaat
     9241 aatgtagttg atatagatgc ttcagcccca aagtttcccc cagtaattat tgtattttgc
     9301 gattggatca gagtggagaa aaaaccttgt tcttgcgttc cgctgactgg tatacccaaa
     9361 atagctcctt gtgtccaatt ccaagtaata tgagcaccaa tagccgtaaa taaacttcct
     9421 gtactgtaga taagtgcgct gaaaaagcaa cctgctaaaa agatattgaa aactgccaga
     9481 aatgtcatgt taggattcaa tccgtgcaaa agagcaaata atgcagcaga tccaatcatt
     9541 gctattaacg gaccaaatct aagcatctga tgctgaaaaa agccacggaa taaaagctct
     9601 tctgatgccc ccactgcaat aaataaaata aaactcgtta tcagcggcac aatgtttgcg
     9661 tttcctgaat ctaaccgata cgcccccgtc aaatataatg gactagtaat aagcagaaac
     9721 actccaattc caacaacgag acctcccgct aaataccccc agtcttttcc tcgaacagaa
     9781 acaccataat cttctattct ttttccttcg accttactag caagaaataa agctagtaaa
     9841 aaaacagcta aatgtccgac cgtaccggca attgctccaa tccattcact atttccaata
     9901 aacatatccg caagtgcatt attgacaaga attcctaaaa caaaaccaac aaagactatt
     9961 aaaacagatc caatcaaccg aataatcctg atcatctttc atccctcctt tatattaagt
    10021 ttaacaaccc ttttctttct tgtctcgtga aaactatgta aatgttctcc atcatagaga
    10081 gaatagattt ttacgaacta agaatatcta cagcaacctt acgaaaatga aagactgtct
    10141 ccctaattct tctgttagac tgtttttaat aaggaaagga tgggaaattt tttgaaaaaa
    10201 caactactaa ttatgtgcct ttcagcatgt gcaattttac tattctcagg ttgtagcaag
    10261 tccaatgaaa cgattgcaac gtttaaaggt ggaacactta cagttcagga tttttatgat
    10321 aacccaaaag ttaaatcaaa taatcaaaca ctattaaaaa aaatgattgt cttcaaagca
    10381 tttgatgatg tatacggaaa agagatttct tcaaaggaag taacaaaaga atataatgaa
    10441 caaatcaaaa aactcggtcc aaactacaag gaacaattaa aagcagttgg ccaaacagaa
    10501 gagacatata agaaactctt taaacagatg ctggctttcc aatacggttt gaaagccaat
    10561 gtaaaattaa cagataaaga tctagacact gcttggaaag aattctatcc agaagttagt
    10621 acacagatca ttctattttc gactaaagaa gaagcagata aagcaaaaaa agaagcaaat
    10681 gaaggagaaa atttctccaa gcttgttcaa gcttatggaa aaaataaaac attaaaggaa
    10741 actgatggaa aaatgaattt tgattcaacc aatccagaga ttcctactga agtaaaaaaa
    10801 gcagcattta aactaaaaaa cggggaagtt tctgatatca ttcctgtaac agatccaacg
    10861 acttatcagc aaagctatta tctagtaaaa atggtaaaaa aacaggataa aggttctaat
    10921 aaagacaaat acaaatctga gctagaaaaa attgctaccg aagcaaaaac tcttgatacg
    10981 gaattcatgg ataaaacaat ccgtaaagtg atgaaaaaag acaatgtaac tattaaagat
    11041 ccttatgtaa aaaatatatt caaataaaca aatttgaccc aattggggat gtggcaaaat
    11101 ttgagaagtg atttttggaa attccttctt atttttgagg caaaccactt ttgccacaac
    11161 ttcatcgggg ccttttttta tttgtaccaa aacaaatcac tggatttgtt acaatcatga
    11221 ggatataatt taaaaaagtt ttttatttct atcacatgaa tcaatgcgcc attaagtaga
    11281 ttctttcatg cttccctatt ttttcacttg ccgtatcgct tcaaaaacaa ctatcataaa
    11341 ctcaaactcg actgaaaagt tattttaaaa aagactaaaa atatcccttc tggacttgtt
    11401 cttcttattc tgttatacta gagaaacacg aaagatattt ttatgcgaca cttttcattt
    11461 gtttttatga aatttattca aaactggcgt aacttcagag ttacaaggat gtattagagg
    11521 ttagggaata catcgtttaa atgagaaata agtaatagtt agtaatagtc acccaaactt
    11581 taaattaatg aatattgaat cgtcagatag cctcctcgag ttttcgagaa ggctatcgtt
    11641 tattttatgg agaaattgat tcagaagtaa tcagcgacct tttttagttc accaatcgtt
    11701 tctgcttgga aagtttgcac ccaatcttct tggaagcccc tcactgcttt atcaatcgag
    11761 ggcatctcta atacttgatc tagtagctct ttacctaacg ttatcgctga gctccagatc
    11821 gaatggctgt agtgacttgt tcacaatttt tgaaactagc tgctaatatt tttgttggtc
    11881 tttgcgtacg ttcgatctca gtccgcaacg aatcaatcac tttcatagca tcaatgcctt
    11941 gattttgcat cctgttataa taaggtgcaa tataatctgc tccattatta atagctaaat
    12001 acccttgtaa ttctgtgtaa atagctgtac cggtaatcaa ataaccttct tttttcaact
    12061 ttttgatcgc ttgaaggcct gcttgattca ccggcacctt gataaacgta tcttttccca
    12121 gttcttctat gataactcga gcatcctcta tcatttcttc ttccgttctt cctattgtct
    12181 gaatatggat aggaatctgt ccgattattt ttttgatttc tttcatatgc gagaagaagt
    12241 ttgacgctcc ttcttttttc agaattgtag gatttgttgt tacgcctgtt aaattcaaaa
    12301 actgttgaca agaataaata ctttttgtat ttgctgtatc aagcatgatt tccatatagc
    12361 tttcccccat tctgatcctc ttgatcgatt ttaatgattg tcccctttct taaatgcggc
    12421 atttccttat cttctacata cattgttcct ggaagttccg gctcatgaga tccatcaaat
    12481 tttatcgtga tatgtcctaa ttcattcaaa ttagtttgga caacatctcc tactgctgtg
    12541 attacataca tttgtttatc aaaacagagc ttcatatcac aagttatttc ttttcttacc
    12601 tgattcaatt caatcttata acaataatct gttaatgttt ccggtgcttc atctccaaat
    12661 aaaatcatta ttttttcttt cctgaatact tctgcttcta taccaacatc tgttacaacc
    12721 gtttcaaaga tcgtcatctc t
//
LOCUS       DAFLWC010000083        12740 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.085, whole genome shotgun sequence.
ACCESSION   DAFLWC010000083 DAFLWC010000000
VERSION     DAFLWC010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12740
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.085"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            99..542
                     /locus_tag="L1V17_002286"
     CDS             99..542
                     /locus_tag="L1V17_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1237029.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(548..1732)
                     /locus_tag="L1V17_002287"
     CDS             complement(548..1732)
                     /locus_tag="L1V17_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HBN1237030.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            2000..2698
                     /locus_tag="L1V17_002288"
     CDS             2000..2698
                     /locus_tag="L1V17_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBN1237031.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2705..3382
                     /gene="nth"
                     /locus_tag="L1V17_002289"
     CDS             2705..3382
                     /gene="nth"
                     /locus_tag="L1V17_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBN1237032.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3508..4041)
                     /locus_tag="L1V17_002290"
     CDS             complement(3508..4041)
                     /locus_tag="L1V17_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237033.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4338..6719)
                     /locus_tag="L1V17_002291"
     CDS             complement(4338..6719)
                     /locus_tag="L1V17_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBN1237034.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(6709..7356)
                     /gene="recU"
                     /locus_tag="L1V17_002292"
     CDS             complement(6709..7356)
                     /gene="recU"
                     /locus_tag="L1V17_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HBN1237035.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7420..7959
                     /locus_tag="L1V17_002293"
     CDS             7420..7959
                     /locus_tag="L1V17_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HBN1237036.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8049..8468
                     /gene="gpsB"
                     /locus_tag="L1V17_002294"
     CDS             8049..8468
                     /gene="gpsB"
                     /locus_tag="L1V17_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HBN1237037.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8490..8857
                     /gene="rnpB"
                     /locus_tag="L1V17_002295"
     ncRNA           8490..8857
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="L1V17_002295"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9066..10232
                     /locus_tag="L1V17_002296"
     CDS             9066..10232
                     /locus_tag="L1V17_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBN1237038.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10278..11774
                     /locus_tag="L1V17_002297"
     CDS             10278..11774
                     /locus_tag="L1V17_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HBN1237039.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            11855..12538
                     /locus_tag="L1V17_002298"
     CDS             11855..12538
                     /locus_tag="L1V17_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBN1237040.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
BASE COUNT         4273 a         2230 c         2630 g         3607 t
ORIGIN      
        1 tttcttggtt tcagattggg ttttcctaca aaatattttt atctttgttg aataggaaac
       61 aaaaaaacaa tataatgaaa gaaaaagaag gtgtagaaat ggataaaaga caactgctaa
      121 tagaagaata tctggattta gctaatgaga ttattcatcg taataaacca gaaatggaaa
      181 aagaatttgc aggatttact ctaaatgaac tagaagtgat tgaacatatc gggaaaatcc
      241 ctgatcctaa cgtgacaaaa ttagcgaatg ctagttacat gactagagga gccatcagta
      301 agctaacaaa aaaactgata gctagaggga tcataaacac ttatcaaagc gaagagaata
      361 aaaaagaaat ctattttcaa ttgacgccaa tcggacaaaa aataaggaat agacacgagc
      421 aactccatca aaaatgggta cagcgagatg ctactgtatt tgaaaatatg tcaaaagaag
      481 aatttgacac agtatttcgt tttatcggtc gatacagaga atttatacga agtagcaaat
      541 gaagctacta ttttttattg tagtgataat aggcaaaaat cataagcaaa aatccgaata
      601 ccgtcggaag aaatggtgct gcagcataaa gctgtcctgc gattagcggg ccgatgacgc
      661 gcgatagaga ttgtatactt tgggtaccgc ccattacaag accttgctgg ttatctgaga
      721 cagaattgga tagttggcca ttgaatacag gagtaaaaat agaatcaccg aaaccataac
      781 agataatccc aaataaaaac aaaatcggca gtagaagaat tccagataat gtgatgaata
      841 gataggcgag gatttcactg aacatcccta ttcttgtgat ctgctgttct gaaaattttt
      901 tgagcaatcg aggcataatg aacaattgcg agacagtatc caagattcca atcaaagaga
      961 agcttaaacc aaccaaccca gccttccact gaaaggcgtc aatcgaaaat tgagaaaaga
     1021 tagattgaag agagccagct gccaaccaaa cagcaaaacc tgctgtcaat aaaggaataa
     1081 cggatgaaat cttgaataat tgttgtaatt ggtgaaaagg tcttacatgg gagaaactta
     1141 aatctactga acgttttttt attggaaggc tttctagcat aaatgtgtag ccataaacgg
     1201 catttaagaa agtaaagagt gctccaataa atataggaac agaattcccc aactcagcta
     1261 atagaccccc tataatagga cccagcgttg ttcctatacc gactaaagca cccatccatc
     1321 caaaaacttt ggttctttca ttaggttccg tgatgtcggc aaagtaagca tataaggtgg
     1381 agatttctcc tgccgtcaat ccttcaatga tacgaccaag gaacaacatc catatcgaat
     1441 ttcctaaacc aaaaagcaaa tatccgatac ttgatcctaa taaactgata ataaggatcg
     1501 gatgacgccc aaaatgatca cttaagctac cgagaatggg ggcagataag aaggcagcta
     1561 gagcataaac agacatgagc aaagtgatat agaaagcttg ctgatgtatg gagtgagaat
     1621 aaggcagcgt taaaaacgga agtacaggac tgacgatagt aaatcctaat ccagtgaata
     1681 agacagagac gtatccaaaa actttagaat gtttatttgt gaaactgtac atgtaaaaac
     1741 tcctttatgc aataatgtta acttggaaac aaaaatagtg tatagtaatt ttgtttcctt
     1801 gtcaacattc taaggaacag cgaaatctac ttaatttatt tattccgaaa agtgaagata
     1861 cgcatcaaaa acatgaacaa acaaaaatca agtagacgac attgtaaatc tgaccgatca
     1921 gtgaagtaaa tagaaaagaa acctgttctt gcttcccatg ttttttttac gtatactgtg
     1981 attgagcgga ggagaaatca tgttgaattt agaaaattac ttaagcgctg gacaaacagt
     2041 catatctaat cttttactta aaaattatca taggatcggt ctacaatctg aagaattttt
     2101 atttgttcta cagttgcata tggcacagct tgaaggagat actttccctg atttgcagat
     2161 gattgctatg gatatgggaa tcaaacaaga tcagattttt caaatactgg atcgtctcgt
     2221 aacaaatgga tttatcaaga tagaaacgac gattgtcaac ggtaaaaaag cagatcgata
     2281 taatctttac cccatctatg atctattagg tgagtattta aaaacacaag aaaaaaaata
     2341 cgaagaaaaa acacaagaaa aagaaatcca gtcagtgtat caattatttg aacaagaatt
     2401 tggacgcccg ctttcttcga tcgagttcca gcggatcgga caatggctag aagaagacca
     2461 ttatcagccg gaaattttga agctagcact gcgggaagcc gtattaaatc aggcttatag
     2521 ttttaattac gttgaccgca ttttgctatc gtgggaaaga aaaaatctac gtacaaaaca
     2581 acaagtggaa gaagaccaaa aacgaagaaa acagcagctt cttcaaagag aagtagaaca
     2641 gtcagctcaa caagaagaat tgccgaaagt ctcactgaaa aattggttgg aggagtagcg
     2701 gaatatgtta agcaaacaaa aaacaatgga agctctagaa acgatgtatg gaatgtttcc
     2761 cgaagcacat ggagaactca agcacaataa tccatttgag ttattgattg cagtgatctt
     2821 aagtgcccag gcgacagatg tatcagtgaa taaagcaacg ccagatttgt ttgcctcttt
     2881 tccgacaccc gatgcgttag cagaagcttc aatcgatgaa atcattctta aaataaaaac
     2941 gattggtttg tatcgaaata aagcaaaaaa catcaaagcg tgtgcacagc agctgattga
     3001 acgtttcgat gggcaagtgc caacgtcaag agaagaattg atgtctcttc ctggtgtagg
     3061 cagaaagaca gcaaatgtcg tattggggga tgcattcggg ataccagcaa tcgcagtaga
     3121 tacccacgtg gaacgtgtct caaaacgcct gaggatctgc aaactagatg ctacggtcat
     3181 ggaagtagaa gaaacactga tgcggaaagt accacaagaa ttatgggtaa agacacatca
     3241 tacactgatt ttttttggta gatatcattg cacggcaaga aatcccaagt gcgaggtatg
     3301 tcctttgcta tcaatatgtc aagatgggaa aaatcggatg cgtctaaaag aaaaggcgct
     3361 aaaaaagaaa ccacgcctgt agacgtggtt tctttaattg caaataaatg tatgaattat
     3421 cttgttatta tggagaaaag ctgtttcgtt tatctttttt gcatgaaaaa gtaaatgtac
     3481 atactcagta gctaggatgg taacttatta caatttattg cgataaaaat aaaagttgtt
     3541 atttttattg ggaaaatacc cgatgtagaa aataatgcct tccaatatac ctataaaata
     3601 agtccagtat tccaaaggat tatataaata agtgacgtat ctatctaaag gtgtaataaa
     3661 aatgataagt gataataaaa aaataccatt tataactaaa cataaactaa tggatttggg
     3721 cggtttcagg ctcatcagaa aaatatagat tctggtgaac aacaaccata aaaaagtgag
     3781 aatcattgca tgagagcttc tttccataaa ttttccttta agagtagtgc ttaaaagtac
     3841 agaaaaaata ataaatgcaa ggataggagc aattaaagta aatttattta ataataaaca
     3901 aaatttttca gcttttttat tcttggaata acgaggtatt gttttcgata aaaaaagatg
     3961 gtgcagacaa attatgataa ttaagcatac tatcagataa ctcaaaatga agccttcttt
     4021 caaaaaatta ttcaaaacca tatattgtat tttttatttg ataataacaa tgggattatt
     4081 aagaagtggc actaaataaa agactagtgt gtatttagcc gatttaatta taaacaagta
     4141 aatggataaa gtatatgtaa tgataaaaga aaaatggatt ttctaatttt taagctaaat
     4201 gttagatcac acatgtatat gctggatagt cttataaaaa atcatgtaat acagcttggt
     4261 acatgatttt tatttgtagc tgttttttac atagacacaa aaaagaaacc acgcttgtag
     4321 acgtggtttc ttttttacta tctgtttcca gaagctgagg tgctgctgga tggtgtatgg
     4381 tcatttgcag catccgctcc gctagttgct ggctcactgg aagaagcagg aggagcagat
     4441 gaagacggtg tcgagctttc ttcggatgaa gaagaaggaa ccgttgttga agacgctggc
     4501 tcgcttgttt ctgctgtcgt gctttctttt gaggactcag cagttgattc gctttgacta
     4561 gtagagctag agctttgagt cgttgtctct gttgttgagc ttccaggagt ctggacatag
     4621 ctggaagatg gaatagttgt tgatggtgta attgcattcg atctagctgt atattgatct
     4681 ttgtagtaca gttcaccgcc cacacgaatt aatccgcttg gcatctccca gtctgtattt
     4741 gtcacgttag ctgaaacata ctgcataagc tcgcgataaa catcagaggc tacgtgtgac
     4801 gattctgaag tgacaggcgt cattttttta ttgtaacctg tccacacgga aatcgaataa
     4861 tttggcgtat agcccgcaaa taggatatct ggatacaccc cagaagaaat accaagtttt
     4921 gcatactcgt catctgtgta attggatgtt ccggtcttac cggcttgata taacccagcg
     4981 atttgcgcat tcgtaccagt tccttcagtg atcgtatctt ttaaaatgtc tgtgatcata
     5041 taagctgttt ctggagacat ggctgttttt ccatctggct cataagtttc ttctgttccg
     5101 tcttggaaga cgattttatt aacatattga ggtttgtaat aagtccctcc attggcgaaa
     5161 gccgcatagg ctgctgccat ttttaaggaa gaagctccgt attttgtccc atcttgttct
     5221 tccgtattac tagagatcgc attcgattga tggatcgtac tgtattcgat cccaagattt
     5281 tttaagaaag aagccacttt atctgaaccg acttcattga ataatttgac tgctggaaca
     5341 ttacgggata agtaaagtgc ttggcgtaaa gtaatggtgc ccatatattg attatcccag
     5401 tttcctacag gagtcgaagt cccttcatag ttatacggtg cgtcagtaat agtttttcca
     5461 gtagaatatt tcaaatattc aaaagctggt ccgtaatctg tgacaggttt catcgtagaa
     5521 ccaaaatcac gggaagtatt cactgctaag ttgttgccta aagttacgtc ttctgcgatg
     5581 tgacgtccgc caatctgggc ttttactttc ccggtattgg tgtcgataag ggtggaggca
     5641 acttgcatct cgtcgtctgg gtaagagaca tactgatccg tgttgacgat atcatatagt
     5701 ttcttttggg cgtccagatc caaattcgta taaatctcta aaccgtctgt gtagacattc
     5761 ttatctgttt tttcttgtac ttcattgatg acttctttga cataattatc gacgatctta
     5821 gtattgtcat cggattgagt tagttcttgc agaccatccg ttaccggtac attaacagct
     5881 tgatcatatt ctgtttgaga gattttttcg ttttgaagca tcgtatacaa aacagtatct
     5941 cgtcttttct tcgcctgatc tggataaaca taaggatcat aggcggaagg ggcttgaggc
     6001 atcccagcaa gcaatgctgt ttgcggtaaa gaaagttctg ataatttctt accaaagtac
     6061 atctcagaag ctgtctccat cccgtacaag ccgtttgaca tatacacttt atttacgtag
     6121 taggtcaaga tctcttgttt cgattttttt tgttccaatc ttacagccat ccacgcttct
     6181 tgggccttgc gtttcagagt ctgatcctcg gcactggtgg agaagaagga aagtttgatc
     6241 aattgctgtg tcaaagtact tccgccttgc agtccgccag aggtaaagtt agagagggca
     6301 gaaccgatga tccgaatagg gtcaaccccg atgtgtttat aaaaacggcg atcttctacc
     6361 gacacgatcg catcttctaa tgttttcggt aattcattcg cagaaatttt ttcacgcttt
     6421 tctgcgccta aatcttcgaa tagttcgcca tcttgtgtat atagtttgga agatacggta
     6481 gcgtctaatt ttttatccgt caattcgggc gcatcttttg cgtaatacca gaaaagtcct
     6541 acacctgcta aaaagaggat acagaaaaat gagagtattc ctaaaaggat cttgataaat
     6601 aatccttttt tatgtgttcc agaggacttt ccagaacctt tgccagaatt cttcttcaca
     6661 ctctttttag gagtaggctg tttctgtcgt ctagagcttc tagtttgttc atttgccatt
     6721 cttgctttct ccttcaatag ataatgttga taaatagaag tcaaccgcgt ccaaataagg
     6781 aatccgcgga gaaataccag ttttgatctc tattcctagt tcttcgatca aagataaagg
     6841 tagtgatttg cgtccttttt ccttttgggc gtcccagtaa gcaatcaaat gaacactatt
     6901 caaataaaaa cagcgcttca aagacgaaaa ccataacaag acaaagcaga ccccattttg
     6961 ttcgaggcat gctttcatat gttcgatttg atgggcatgg aagtttttaa agggaaaaga
     7021 tgttttgttc ttggtttctt ttgcttcaaa gtccaagtaa aagcctcgat agacgccatt
     7081 atagtctgta gttgaggctt gggtaaagta ggcttccttg atcacagcag cacttctctt
     7141 aggatagtct actttcacga tttggatagg ggtaggcttt ttatggataa ccgccaaccc
     7201 gcgggaaaga taatatttat tactttcatt gattgcttct tcaaagcgca tcccccgatt
     7261 gccgaattca gtgatctgat ttcttttttc ttgaattttt tcgacgggag aggcattctt
     7321 ataataaggt tggccatttg gatagcgcaa taccatcttt aatcacactc ctaggccaca
     7381 ttatagcaaa aaagcggata gaaagaaaag gaatctgaga tggataagtc aaaagtaatc
     7441 tatgtgtctg ggtatcgaag tttcgaactc ggtgttttta aagaaaatga tcctaaaatc
     7501 caagttgtta aaaatgtttt aaaaaaagaa ctccatcagt tagcagaaga agggctggaa
     7561 tgggtacttg tcagtgggaa tttgggcgtc gaactatggg ctgtgcaaat agtagcggaa
     7621 ttgaaagaag aatatccgga actatctctt ggtattttgt atcctttttc tgattttggt
     7681 aataactgga atgaagggaa ccaagaaaaa aaacaattag cagaacaatt agcagattat
     7741 gtcgaagctg ttagccatca accctaccaa tcacctagtc agctaaagaa tcacactcgt
     7801 tttatacttg agcatacagt gggctgtctg ctgatctatg atgaagaatt ccctggaaaa
     7861 acgaagtatt tttttgaaga tgcacagaat taccaagcag atcatcccta cgaaattcgg
     7921 ctgatcagta tggacgatct tcaaaatttt agtgaataat cgatattgtg tttgatttat
     7981 caactttttt cctatacaat gaaaaaggta gaaatgttat tacgtaaatg aaaactagag
     8041 gtgtaaatat ggcgaatttg gtttatagtc ctaaagacat tttacaacaa gaattcaaaa
     8101 caaaaatgcg cggctatgat cccgttgaag ttgatgaatt cttagacaat atcatcaaag
     8161 attatgaaac ttacagcaaa gaactccttg ctttacaaga agaaaacgat cgattgagtg
     8221 caaaagtagc tcaattatct aaaactcaag gagcagctca aacacgcgtg caacaaacag
     8281 aggcaccaaa gagcgcagca gtgaccaatt ttgatatctt aaaacgcttg tcaaatcttg
     8341 aacgtgaagt atttggtaaa aagcttgatc aacaagcaag tgcagtcaaa ccagcacaac
     8401 ctaatccaaa taactacaca aatgcagaca caagcttaga tgataatgaa aaaacacgtc
     8461 aattttaatt tttgattaat gaatttgcgg ttttcgggta atcgcggtct gacttgatca
     8521 ggctgaggaa agtccatgct cgcacaggct gtgatgcctg tagtgttcgt gcttagcgaa
     8581 accataagct aaggtactct ttggagtaac ggcaggaaaa caagctaagg cttcggctat
     8641 gcttaagtat ccttgaaagt gccacagtga cgaagcggct ggggaaaccc atccggtgga
     8701 acgcggtaaa cccctcgagc gagcaaccca aacaatggta ggggcgcttt ttgtctggaa
     8761 gaagaacagg acaaaaaggc agtataactg cagatagatg gttaccgctt tgttttttct
     8821 ccctggaaaa gcaaagtaca gaacatggct tatagaaaac cgcaaacatc agggaattag
     8881 gtcgtgacaa aagtaatgcg ttataagaaa caagaaaaac atttgaaagc tatttttcaa
     8941 tacttcagat gaatcgttct tattacaaaa caaacttttg tatcaccggt tattcggaat
     9001 ttgagtaaaa gtgtggggta ggactgatgt cccacctcct ttttttataa ataaggagat
     9061 tgtgtatgga aaaaaacagg aagttcaacc tcgtcgcaac tgcggcaagc gggctagaag
     9121 cactggttgg taaagaatta agagatcttg gaatcgaatg ccaagttgag aacggacgtg
     9181 cacgttttga aggaacaatg gaaacgatcg ctacagctaa tttatggtta cgtacagcag
     9241 atcgagtaaa aatcgtggtt ggggaattcg atgcgtatac gtttgatgaa ttgtttgaaa
     9301 acgtaaaagc attgccttgg gaagattttc ttccactaga tgcagctttt cctgtagctg
     9361 gaaaatcgat caagtcgaaa ctatatagca cacctgattg ccaagcgatc acaaaaaaag
     9421 caatcgttga acgtctccgt acctattatc accgtccagc ttctgtacca ctgacggaaa
     9481 ctggcgcaca ttttcagttg gaagtagctt tgctgaaaga ccatgtgatg gtaactctgg
     9541 atacgacagg accaagttta ttcaaacgtg gttatcgctt agaaaaaggt ggagcaccat
     9601 tgaaagaaaa catggcagca gcacttatta tgttgacaaa ttggcgaaaa gaccgtccat
     9661 tttatgatcc tgtatgtggt tcaggtacgc tttgtattga agcagcctta ataggccata
     9721 atatcgcacc aggattcaat cgtgagtttg cttgcgaatc ttgggattgg ttcagtcaag
     9781 aaatcatgga aaatgttcga tcagcagccg aagaaaaagc agattatgat attgaattag
     9841 atattactgg ttcagatatc aatggacgga tgattgaaat tgccaaagcc aatgcagaag
     9901 aaatcggatt aggctcttcg attaccttta agcaacaagc agtcaaagac ttcaaaacgg
     9961 ataaagaata cggggtcatc gtggctaatc cgccttacgg agaacgtcta ggagaagaag
    10021 aaactgttcg gaaattatat aaagaaatgg gcgatgtatt ccgtccatta aaaacatgga
    10081 gtaaatatat cttgactagc gacttagcgt ttgaggaatt ttacggacaa aaagcaacca
    10141 aaaaaagaaa attgtacaat ggtgcattgc gtacggatct attccagtat tggggaactc
    10201 gtccgcctag aaaaaaagag aaagacgaat aatcttacta attgattcat tcaattggat
    10261 gtttggagga atagggaatg aaagaaaaag agtttttaca agaagtaaaa gaaatcaatc
    10321 ttctacaaca agctttagga atcctcgatt gggatacaca aacaggtatg cctgaaaaag
    10381 ctagtgcata ccgaagtgaa gtagacagct atctttacag catttatttt tcaaaaaaaa
    10441 tcggtccaaa aatcaaagaa gccattcgct atttttctga acatccggaa gaattgtcgg
    10501 aagttggaac tgccgttttt gccaaagtaa aagaagagta tgatttggaa catcgcgtac
    10561 cggaagatct tatgagaaaa tatacagctg ccgtttcttc agcacacgga caatggcaaa
    10621 aagctagaga aacacaacaa ttttctgatt ttcaacacgc attgaatcaa aatattgaat
    10681 taacaaaaca gttgatacct tactggagaa aagatgaaaa gacgaattat gatgttttgc
    10741 tgaatcaata cgaacccggg atgactgtcg aaatccttga taaggtattt gatcagctta
    10801 aagaaggaat tctttcgatc cgccgtacgc tccaagaaaa agggactgaa cctgaaacag
    10861 actttttaaa tcggagaatg acgaaaaaac aacagaagag atttgtagtg aaagtaatcg
    10921 aacaacttgg ttatgatttt agtcgtggtc gtttagatga cactgtccac ccatttatga
    10981 ctggaattaa tccgaatgat gcacgaatca cgacacgatg gaacgaaaca gatttcaaaa
    11041 tggctgtttt tggagtgatc cacgaggctg gtcatggtat gtatgaacaa gacatcgatg
    11101 ataaatatgc gtatacaccg gtttatgaag gtacatcaat gggtatccat gaatcacaat
    11161 cgttgtttaa cgagatcatt attggaagta gtcgcagctt ctggaaaaag caatatcctt
    11221 tctttcaaga atgtgcagaa ggaacattcg atgatattcc ttttgacaaa ttttatcgtt
    11281 cattgaacca tacaaaatca agtttggttc gtatcgaggc agacagtttg acttaccctc
    11341 tccatatcat cattcgttat gaaatcgaaa aaatgatttt caatgaaggg gtagatgttg
    11401 ctgaactacc tgaaatatgg aatcaaaaat atgaagagta tctgggaata cgaccaacaa
    11461 atgatgtgga aggcatccta caagacgttc attggtcagg tgcaagcttt ggttattttc
    11521 cctcttatgc attagggtac atgtatgcgg cacaattact tcattctttg cagcaagaaa
    11581 tagatgtgga aaatgttcta gcgtcagacg attattctcc aatcaaaaac tggatgtcag
    11641 agcatatcca tcaatatggt gcatctagaa aaccaaatca attaatcatg gatgcaacac
    11701 atgaaccgct taatccgcaa tacctgatcg actatatgaa agacctgtat tttaatgtat
    11761 atcaggtaaa ataaaataca atttacaaag atagctgaaa ttcatctaat ctatagatgt
    11821 tttcagctat ttacttaaga aagaagtgga acgaatggat aaattacaag tgatcgctga
    11881 ttatagtatg gaccaattag cgcatgatca aacaggacat gggagcgatc ataccaaaag
    11941 agttgtcaag ttagctgaaa aaattttgga gacggaaccg caggcagacc gctttgtgac
    12001 gcttgcagca gcttacctac atgatacgat tgatgataaa gtcgttaaaa atgagaacga
    12061 ggcaaagcaa cagcttcgtg tattccttcg ctctttgcca atagtagagg aacagatctc
    12121 gatgattttt tccattatcg aaaatatgtc cttttctaaa aatctctctg aagcggccga
    12181 actatctctg gaaggtaaga tcgttcaaga cgctgatcgt atcgaagcat taggagcaat
    12241 cggcattttg cgtactgctt atttcggcgg tggacatggg cacccgattt ttgatcctga
    12301 actgtatccg caaacattca aggacaaaga aaattaccga aaaggcacga cagtgatcaa
    12361 tcatttttat gaaaaactgt tcttgctgtc tgataaaatg aatactgatt acggatatga
    12421 agaagccaaa cgaagagaaa ccttcatgcg tgaattctta gaagaatttt ttctggaatg
    12481 gtctattgac gatgaaaatt ttactccaga caattggatc aaaaataaca aaaaatgatg
    12541 gaggttgtga cagaagtggt cagctccaag atatttcgga tcattttccg taaaagttac
    12601 ttctggaaca ctgtttacca agaggtcgtg agcctgccgt tcagctccga gtcacaagga
    12661 acaatttcaa aaaatagctt ctcgtgtttg atgaatattg taacttgtga ttcggaattg
    12721 gcaggagaac accgtttatt
//
LOCUS       DAFLWC010000084        12606 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.086, whole genome shotgun sequence.
ACCESSION   DAFLWC010000084 DAFLWC010000000
VERSION     DAFLWC010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12606
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.086"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(52..1581)
                     /gene="ahpF"
                     /locus_tag="L1V17_002299"
     CDS             complement(52..1581)
                     /gene="ahpF"
                     /locus_tag="L1V17_002299"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HBN1237041.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(1591..2154)
                     /gene="ahpC"
                     /locus_tag="L1V17_002300"
     CDS             complement(1591..2154)
                     /gene="ahpC"
                     /locus_tag="L1V17_002300"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBN1237042.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(2298..2960)
                     /locus_tag="L1V17_002301"
     CDS             complement(2298..2960)
                     /locus_tag="L1V17_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1237043.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            3144..4790
                     /locus_tag="L1V17_002302"
     CDS             3144..4790
                     /locus_tag="L1V17_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBN1237044.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            4781..5863
                     /gene="uxuA"
                     /locus_tag="L1V17_002303"
     CDS             4781..5863
                     /gene="uxuA"
                     /locus_tag="L1V17_002303"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBN1237045.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(5971..7524)
                     /locus_tag="L1V17_002304"
                     /pseudo
     CDS             complement(5971..7524)
                     /locus_tag="L1V17_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            7672..8813
                     /locus_tag="L1V17_002305"
                     /pseudo
     CDS             7672..8813
                     /locus_tag="L1V17_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(8939..10018)
                     /locus_tag="L1V17_002306"
     CDS             complement(8939..10018)
                     /locus_tag="L1V17_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBN1237046.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(10121..10561)
                     /locus_tag="L1V17_002307"
     CDS             complement(10121..10561)
                     /locus_tag="L1V17_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1237047.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(10618..11028)
                     /locus_tag="L1V17_002308"
     CDS             complement(10618..11028)
                     /locus_tag="L1V17_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBN1237048.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(11208..11642)
                     /locus_tag="L1V17_002309"
     CDS             complement(11208..11642)
                     /locus_tag="L1V17_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBN1237049.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(11742..12590)
                     /locus_tag="L1V17_002310"
     CDS             complement(11742..12590)
                     /locus_tag="L1V17_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBN1237050.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
BASE COUNT         4212 a         2347 c         2243 g         3804 t
ORIGIN      
        1 tcttgtcacc atcctttttt ccgctctctg actttttaca atcttcatag ctcaagtgcg
       61 catcagataa tcgaatgctc ctaaagctgc agtagctcct gaacccattg aaacaatgat
      121 ttgtttgtat ggactatctg tacaatcacc agctgcgaaa acgccgggga tattcgttgc
      181 gccatttttc tcggtcacta tttcatttct tggattcatt tcgatcgttc catctagcca
      241 atccgtatta gggagtaagc cgactagaat gaatactcct gaaacagcta gtgtatgcat
      301 ctccatcgta cggcgatcga tataggagag agattctacc tgattcgtac cgctgatttc
      361 tttcgtcgct gcatgtttga taacagtgac attcgcaaga gagactagtt tatcctgtaa
      421 gatttgatct gcttttaatt ctggtaagaa ttctagaaca tatacatgtt ttgctaaccc
      481 agccaaatcg attgctgctt caacaccaga attaccacca ccgataacag caatctcttt
      541 tcctttaaat aaagggccgt cacagtgtgg gcaataagca attcctttat ttttaaactc
      601 tttttcgcct ggtacattga tagaacgcca gtgcgcacct gtcgcgatga tggcggtttt
      661 tgctttaagt gatataccgt tagctaagcc aatattaata aaatgttgct ctttatttaa
      721 ggaaacggcc tgttgattca tcataatgtc gatagggtaa ctacgcacat gactttctac
      781 ttgctgcatc aattttggac cttctgtgta agaggtacca atcatatttt caatccctag
      841 tgtttcaacg acttgtccgc cgaaagaatc agcgacaagt cctgtacgga ttcctttacg
      901 tgctgcatag atagctgcac tactagctgc tggtccaccg ccaatcacta atacatcata
      961 aggttctttt tcaaacaact cttcttcaat caaagggcca gtgatttttt caacaatttg
     1021 ttcgatcgtc atgcgtccgc tactaaattc ttctccattt aaaaacacag ttggcactgc
     1081 catgattttt ttatcatcga tttctttttg gaacatccca ccttcaatca tcgtatgagt
     1141 aatatttgga tttaatacag ctaatatatt caatgcctgt acaacgtcgg ggcaattatg
     1201 acaagtcaag ctaacataac tgtcaaaatg caatgtttgt gttatttttt tgattttaag
     1261 actcaaagat tcactgattt tcggtgcccg tccactaatt tgtaacatag ccagtaaaaa
     1321 agaggaaaat tcatgaccga gggggatacc agcaaaaacg attccacttt ctttgccaac
     1381 tggattgata gaaaaactag gtgtgcgcat cgaatctctt ttttcccaag agattttagg
     1441 agacatttct gctatttcct tcgtaaattc agctagtttt tgactatttt cactattatc
     1501 caaactaaca gaaaaaacaa taggagattc aatcagtgct aaatattgtt cgagattttg
     1561 tttagtttct ttgtctaaca tatccaccac ctaaatcttt ccaacaagat caaaacttgg
     1621 tttcaatgtt tcgccacttt ctttccattt tgccggacaa acttcacctg ggtgggtacg
     1681 tacatattga gcagcgcgaa tcttatcaat cagtgcacta gcgtcacgac cgattccatc
     1741 tgcattgatt tccatagctt gaacgattcc gtctggatca ataataaatg ttcctcgctg
     1801 agctaatcct tgctcttcat ccaaaacatc aaaaatacga gaaatctgat gagacggatc
     1861 accgatcatc acgtattcga ttttaccgat agcatctgat gtatcatgcc atgctttgtg
     1921 agtaaagtgg gtatcggtag agcaagaaaa gacttcaaca cctaaagatt tcaatgtact
     1981 gtattgttct tgtaagtctt ctaattcagt aggacaaaca aaagtaaaat cagctggata
     2041 gaagcaaaga atactccagt tccccataag atctttttca ctgacttcta aaaattctcc
     2101 ttgatgataa gcatgtgcat taaattcttc gatttttttc ccaatcaatg acatagtaaa
     2161 acctccaata ataattattt atttataatt attgtaattt agttggagtt gcaaagtcaa
     2221 tggatatttt gttatttaat aaagattact caaaaacgaa ggttaattat aaaaatagaa
     2281 gaggtcgcaa gaaaatgcta ctgctggaaa tactcgggat aacgttgagt aacagtttcc
     2341 tgttctttca gcatcatgtg taagtgcaat cccgtttgaa atcgagcttc ttctggtttt
     2401 ttatcaacta aagccttgag taaatcataa tgttgttcca tgatcgtttc ccatggaagc
     2461 ccctgaatgg tcactcgtaa ccagcggaaa cgttctaaat gggtattatg gtcatctaac
     2521 cagttccaaa cttcttttct tcctgcaatt tcgaaacaag cttcatgaaa taaattatct
     2581 gcacggaaaa aagcgcgttc gtcatttatt ttgactgctt tttcttgttc ttctaaaatc
     2641 gtttctagca ctattcgtgt ttgtgtgtcc aatttggaac aacattcaat catgatttgc
     2701 tcttccaact gttctcggac aaagcgagca ttttctgcag aaacaagatt aattttggaa
     2761 acatacgtac cactttgagg tatcgtatac acgagttctt gctgacgtag ttgaatcaat
     2821 gcttcgcgaa tgggagtccg gccgatagca agatgttcct ccagtgcctt ttcagatatt
     2881 ttccttccag gttctaagtc agcatagata atttgtttac gaatcgcttg ataagcttgt
     2941 gattgcaagc tgcttttcat ctttattcct ccaaaatcat ttctatgaac gtagtataac
     3001 agaagaggtc tgaaaaacaa tctggtatgt cacattaact agtaaatttg tataaatagt
     3061 aaaattttgg ttgacatagc gatttttatt gcataaaatt cacttgaata caaaaactaa
     3121 tatgttagtt taggagggga aaaatgattg atttaaacaa ctggaggaac tttatccctg
     3181 aattatctca aaaagaagta gaaatacctc attttgaccg tgcatcatta agagaaaatg
     3241 gacaaaaaaa tcctgtctgg atccatttcg gtggcggaaa tctttatcga ggatttcatg
     3301 cagaaatcgc tcaacgttta gcggatctag gcgaattgtc cactggtgtc attgtttgtg
     3361 aaacattcga tgaagaaata attgaaaggg cttaccaaga ttttgatgat ttgattcttg
     3421 aagtggtcat gccaagcagt ggagagttcg tcaaacgtat attagctgcg acagctgaca
     3481 gtctgtattg tcatccagat tgttctgaac actttgataa gatgattcga cactttgaaa
     3541 atcctagttt acaattagtt acttttgcta ttactgaaaa aggttatcga ttgaaagata
     3601 caaataataa atatatagga ccgattgcag tcgatataaa aaatggtcca aagaagccat
     3661 cacatacaat gagtattctt gctgtgctac tttataaacg ttttttatct ggagcttggc
     3721 cgattgcact tgtctctaca gataattttt cacaaaacgg tagtcaatta cgtacttctt
     3781 tgctaacgat cgcaaaagaa tggcaaaagg aaggttatgt acaaaataca tttatccaat
     3841 acttatcgaa tgaagaaatt gttgcgtttc catggacgat gattgatcgt atcaccccga
     3901 atccttcctt gtcagttagc aaaatgttgg caaaagaggg cttttcaaat atgtcgattt
     3961 tccaaaccgc aaaaggaaat aatattgctc catttgtcaa tacagaggac atccattatt
     4021 taatcatgga agatcatttt cccaatggac gtccgaaatt cgaaaaagct ggggtattct
     4081 tgactgatcg tgcaacggta gataaagcag atacgatgaa ggtgacgact tgccttaatc
     4141 ctttgcatac gtctttagct attatgggtt gtttactggg gtataggagc atagctgagg
     4201 agatgaaaga tccagattta tcgctgctag tttctgaaat cgggtacaat gaaggcctcc
     4261 cagttgtgga gtctccaggt atcattgatc caaagatctt tctggaagaa gtaattactg
     4321 tgcgcttttc taatccaaat attcctaata tgcctcagcg aatcgccacg gatacctctc
     4381 aaaaggtggc gattcgttat ggtgagacga ttaaaaaata tatggaaata gaagttaaag
     4441 acccgcagac acttgtattc ataccattga ctctcgctgc ttggcttcga taccttattg
     4501 gcattgatga tcaaggaaaa ccattcatcc cgagtccaga cccactattg acagaccttc
     4561 agcataagct ttccgatatt caactgggta cgcaagatac atcacatatt catgagaaaa
     4621 tggctcctat tttgtcaaat aaagaaattt ttggtgtaga tctttaccaa gcagagcttg
     4681 gcagaaaaat agaagaaatg ttcatcaaga tggtagcagg accaaatgcc gtacgaaaaa
     4741 cattacagga ttacttacaa gaacatggag gaaatttatc atggaaatga cttttagatg
     4801 gtacggatca caggaagaaa agattacctt agatgaaatc agacagattc ctgcggtcaa
     4861 agggattgta ggcacattga tggatatacc agtaggagag gtatggccta gggagaggat
     4921 caaagaacta aaagaagaaa ttgagtctcg tgggttaaca ctaaaagtaa ttgaaagcgt
     4981 caatgtgcat gatgccatta aaattggatt accttcccgt gagcagtata tcgaaaacta
     5041 taagcagaca atccgaaact tggcagaata tggaatagaa gtcatctgct ataattttat
     5101 gcctgtattt gactgggtga aatctgacct tgactaccgc ttagaagacg gctcatccac
     5161 gttagctttt atatctgatg atattccaga tgatccaaga gaaatcgtcg cgcgcatcga
     5221 acattccagc aatgaatttg gattgccggg atgggaacct gagcgcttag ctcctatcaa
     5281 atccttgctt gaagcctatg catcagtaga cgaagaaaaa cttcgagaaa attttgccta
     5341 ttttctccaa tcaatcatcc caacatgtga agaggtaggg gtcaaaatgg ctgtacatcc
     5401 agatgatccg ccatactcga tttttggatt agctcgaatc gtaaagaatc gagaagattt
     5461 agattggttg tgtcgcatag tagacagccc ttataacgga atcactcttt gtacagggag
     5521 tattgcagaa gatccagaaa atgatgtata tgggatttta gcagaatttt gccaaagaga
     5581 tcgaatccca tttgcacatg ttcgaaatat taaattttta gctaatcgag atttctatga
     5641 ggcaccacat aaatccgaat acggttcatt agacatgtac cgcatactaa aaacaatgta
     5701 tgacaacgga tttaacggat acatccgtcc tgatcatgga agaatgatct ggaatgagac
     5761 aggaagacca ggatacggct tatatgatcg agcattaggt gctgtttatc taaatggatt
     5821 atgggaagca atcgaaaaag gaaacaaaag taaagataat tagtgaaaaa aactgtaatt
     5881 ttattatgta aataagaagg atgttcaaat tcttgataca taaatccgga ggttgttaat
     5941 aagcattcgg atttatgtat cttatttggt ctaggaagta acttgatttt cttttttcga
     6001 ttgatccatg agtgcttctt cttttaattc aaagatatat tctgagatcc tcataatcac
     6061 ttttttccag tcttctggtg tgatgattcc ttttaaaata tagatttttt tgatatgaga
     6121 aggcaattgt ttcaaagggc agtcgctgat aacgatgttg cagttctcca taaaatcatt
     6181 ttgtattttg atcgattcat ttgaaaaaat ttgttctatc ttaacgatca gatctttact
     6241 gatataaaaa tcacgcgtat agttcacacc aatcacaatt cgcggctgtt ttttgtagcg
     6301 atcatacaaa tgtactaggt cttcaaccat ccattgcaca ttttcctttt ctaaaataac
     6361 tggtaacaag tgttgatttt gttctctgaa atccatataa aattgttcaa tggcggtttg
     6421 gacttctttc aatacgctat gttcttgata aagcatgaaa gtaggaaggg gcgtatttgg
     6481 ttgattgaag ttaagaaatc cattataaag tttatttcgt gcgaatgcca atgagtaaag
     6541 aatcttttct ttttcaggta taaacaaatc aaatacagta caaagggact ccaccatttc
     6601 tcttgaataa agaacatgag gaacgtttgc tttttttaaa agtttgtatt gctccaagct
     6661 tgtttcttcc gattcgattt tcgtgataga aagtcgagct aaaatattca ctaagatgcg
     6721 ttgttcgcga caaattggca gattaggtcg caaaatatct acagagagat caataaaaaa
     6781 gtcaatatat tcatactctg tgaattcttt ttgtacgtct ttcacagaag ttgcaggaaa
     6841 attctcttta catattttta atagaaaata taatttatct atcataccgc tatttagtcg
     6901 gtcaagtact tcttttttaa aaaaagtatt catcataaaa gccactactt gcggatcttc
     6961 atcataaaat tctgtagcag tacttgaaaa gatgttccaa taaatatcta atgctgcata
     7021 ttgaatttgt acctcttttc cagaaaaaga ctttctgcca ttattagaaa aggagataga
     7081 caaaccgtac tatgctaaaa atgcattaat ctttttcatt ttcgtataca aataagaggc
     7141 actatagttt gtttgctgac tgaaactgat aatcgaattt gtctgacagc tgaacaaaga
     7201 agtcaagatc tgataactga ctgattcgtt gcagtatctt ccaaatagac gataatagca
     7261 gtaagccgga tcaattcctt caaaattcaa ctttaaaaaa ggtttttgct tatcaatatg
     7321 cagttctgtt agattgagac gctcaaagtc ttgttctaat tctttgatgt atagtaaaaa
     7381 atttgattca gacatatgga aatgatctgc taaatattgt gtagtaataa agaaacgatg
     7441 ttcagatagg aaaagaaaaa tatctaattt tgtattgctt tttttcttca agataaacgt
     7501 tttaatcgct tcttgagttt gcatgaaaga ggctcctttt tacttaaatt gttaaaactt
     7561 gaaaatatta ctgttttttt cataaattta gacaaaaaaa cagtaaacat ataggtagaa
     7621 tctctactat cttatttctt gcatacaaaa aaatcaagga gtgagagagt tatgagatat
     7681 tcaaccatct taatatcaac atttgcagcc ttaagcttat cgcttactat aaatcagaca
     7741 gtccacacag aggagacaga aacagccaaa tggacagaaa ccaagtgggc caacgtcaat
     7801 cgaattacct ttcaggatga attttcatcc ttcaattcag gagtcgcaaa attaagaaaa
     7861 ggacaaacag cgaccatcaa agcaaaaatt gactattcgg gagacttagc acctatacta
     7921 caatcagctg ttacatttga gaatgttgat cccactttgt cgattggcta tgacgagaac
     7981 actttgacta tccaacacaa gcaagcgata tttaccttca ccgttacatt aaatcaggac
     8041 ttgttaaaac cagcgctttt tactgtcaag gtatcagatg gactaccgaa cgatcatcat
     8101 ttaacgccgt atagtcagcg gcagacaatt gagcaagatt cagccatcga ctcaggagga
     8161 gatcttgttg aagaaccaac agataaacca gaaaatgaaa ataagccaga agtaccgcct
     8221 acagaaaatc cagacggaga acagaaaccg gaaatagaac ctggagaaga acccgataca
     8281 gaaactcaac cagagccaga caataaatca aaacctgaaa taacccctgg agaaaaacca
     8341 gatgtaactc cagaaccaga tacggattct ggaaaccaaa cagtaccgga aacaaatcca
     8401 gacacagata atgaaactga aaatccagaa aaaccagagg tagatccaga agaaaaacca
     8461 gatgtgactc cagaaccaga tacggacgca agagaccaag gaataccaga aaaaataaac
     8521 aaaaaaacaa ttcaagagga tggaaaaaaa gagagtaaaa aatcaaatct agcaattcta
     8581 aaaataaatg aagagcagct gaataaaaaa tcacgaatat ttgatagcgc ccaatcagct
     8641 gaaaccttaa aaagtagcaa ggatacaacc tttgctgtcc tgaaacgaaa aataaacagc
     8701 taccaaaatc cggagagtca caaaacaaag ttatactgtg gagcggaatc attctattaa
     8761 gtatagcaac aatgctttct gcaaaaagat ttaaacaaaa cagatctctc taacatttga
     8821 ataatgtctg tgaacgcatt tttcaaataa aaagaaatat ccagaaaatg accccaaaat
     8881 accagattga aatctgatat ttggggtcgt tcatacttta tctttcttca tatttatttt
     8941 aagggatatc tgtttctttt ggaagatggt tcgggatctt tttcactttc aatacatcta
     9001 aaaagaaggt aaagatcgga atgccgacaa tcaagcccca aacgccaaag aaccgttcgc
     9061 taacaagtaa gaccacaaat gtataaaaaa tcggcagttc tgttttgctg gacatcaact
     9121 tcggattcag cacataagac tcaattagat ggacaatcaa aatcgtaatc aggatataaa
     9181 caacatctcg gatgcctcct tgggaataag ctatgaaaga tagaggaata caagaaatga
     9241 taacacctgc tactgggatc agacttaaaa tgaaaatcat gatcgctaaa ctcagcagct
     9301 gatgaaagcc aaatacagcc aaggcgattg tagtgagcaa cgtatttaaa agagcgacaa
     9361 caaattgagc ttctaatacc aaaccaaatg tattgacaaa cttatcggca aaatagtaaa
     9421 tatcttgaaa gaaccaagaa aattcacttt ttaaaaacaa tcttgagaat acaattgttt
     9481 ttttcttttc aatcataaaa aagaaactta agatgaatga catagcaaac gccactgcca
     9541 tttttcctat atcctgtaaa tagccaagcg caatcgaagc gccattttga agctgttcaa
     9601 aaaaatcgtt tcgctcaata taagtatgga tatattgtaa aacaggatct gcatcttttg
     9661 gctgatgctc gtaaaaatta ataacggact ggatcatgtc aaatgtttga tgaataagca
     9721 tcgggatata ctttgtgaat gccagataga taaggtaaac gatcagtgta taaatcatga
     9781 tagctaaaac acctgtaggg attcggacaa atcgctgaat gatttgaaca agatgaatca
     9841 tcaaataagt aaagataaat gtgagcaaaa tggttgtaat catacttcta actaagaaaa
     9901 gaacaaaaac gacaaataat aaaacagtga gacggcgtat tttttcattc gccaaaaaac
     9961 gctgataaac ggtcaaatcg acaacctcca aataacaaaa aataaacacg ttattcatta
    10021 tatgatggaa tatgaaaata agaaagagca aaaagaaaaa ccgctaaatg acgttatctt
    10081 atgagttggt tttcctcata aaatcgttca tctagcagtt tcagcccttt ttctggtctt
    10141 gatgaaaatt atctagcatt tttcgggtca gatgttgcag tgtatccaat tcttcctgtt
    10201 caagtggaag ataagacttg atcttttgtg gaataccttc tgcttgtttt tgcaacgcag
    10261 caccttgagc agtcagcgta acatttacga ttctttcatc acccgtttca cgctgacgat
    10321 taatataatt tttttctgct aactttttta gtaagggagt cagcgtacca gaatccagac
    10381 acaaatcatt tcctagctct ttcactgaag tctttttctt ttcccataaa actaacatca
    10441 caagatactg ggtataggta agattcagcg gcttgaggag gggagtgtag tgtctaatga
    10501 tttctttaga ggcggcatat aaaggaaaac atacttgatt aactaaatat agatcttcca
    10561 tttttccacc tccgctgttt tactatagtg tatcatagcg gatttacaca aaaaagtcta
    10621 ttcactaact gctttcagag taacttctat atttccagct gtagcttttg aatacggaca
    10681 cactttatgc gctgcctcta ataattcttg cgtttcttcc agagaaagac cttcgataga
    10741 tccttcaatc tctacaccta agacaaagct cgtttcactt tctgaataaa gggaaacttg
    10801 tgcactgaca gtagaagccc cagagatatt tttttgctgt ttgatcaatt ctaatgcact
    10861 gttaaaacat gcactgaaac cagctgcaaa caattgttca gggttggttg cattttcgac
    10921 gcgtttacca ggagctgcaa tattcaattc gaatgtacga tcgggattat gcacttctcc
    10981 agagcgtccg cctgtgttga tcattttcgt agaatacatt tttttcataa agttaccacc
    11041 tttaattata ttttatacaa ttgaatttta cacaatataa ttgtggaaag caaagaaatg
    11101 gattggcata agataaataa gagaaagcac atgaaacaga cgcgctttct cgaatagcaa
    11161 acatatacaa aaaatatcag agacaaaaaa taatctcatc ataaacatta catatatttc
    11221 tcaaaaagtt gttttctttc ttcaaaaatt acttcacgat ggacctgatg aagcatccat
    11281 aaataaccaa aaggatctct gaacattgag ttagtcacac caaagtccat catttctgtc
    11341 atttcttgaa tctctacaca gccatttcgt aatgctttat tatgtgtgtc ctcgatatca
    11401 gagacgatga tattgaacca gatcgtattt ggatgttcag cagtaggagc agtcaaacca
    11461 agagacgtgt tttcatccag catatggaat ctcgtaccat acaaggtaaa aatgacttca
    11521 ttattgcctc tagggtaatc tgttgcctca atcagttgta tttcatcaaa gattgtttga
    11581 tacagttcta gtgctttcaa actatcattt aatacaaaat cgatttccgt tcctttatgc
    11641 ataaagatct cctctccttt tcagtcgaac agttactaga ttcttttatt ataccagcta
    11701 aagaaaacgc attcaaaaaa atagcggatt tacttaccaa ctcattcgat tggatgataa
    11761 gtaaatccgc gtcccattac ttctgctacg ctgctgacaa tgacaaaggc acttggatcg
    11821 atttcttcta tcaatggttt cattcgggaa aattcatgat cagtcacaac gatcaataaa
    11881 acctcttttg actttcgatt atacccgcct tttgcctcta gcagggtaag gccacgtcca
    11941 atctcagcac ttaagcgaag gcggatgtct tccaaataat gttcactcat gaccataaca
    12001 gatttctttc gattgatacc tgtttcgata taagtcatga caattgaagt gattgcaata
    12061 gataaaatag cataaagaaa ctcttctatt ccaaaaataa acagattaag agaaacaacg
    12121 aatgcgtctg taaaaaataa gccaatcgaa gtattcaagt ggaaatattt tttaaaaatg
    12181 aggggaggga tcgtcgtacc gccgctagaa gagttgtttt tatataaaat cgcaactcct
    12241 aaagcaaaaa tcgcacttcc aaaaatgaca gacaacaacc gatctgaagt aatcattgtt
    12301 tctggaacta ttgcaatgat taaaggaaaa accaagcttc cgaaaagtac tttaaaaaag
    12361 ggttttttac ctaaaaatag aagagctagt accaacataa cgatattcaa cactaaaata
    12421 actatagctc ggtcaaagcc taaagcagct tccagtaata ttcctagacc gctgacacct
    12481 ccagcagcaa tatgatgagg ccctaaaaac atattgatag cgactcctaa tatgaagagg
    12541 gcaaaaataa tcttaatgta tgtccatata aattgtctcg tttctttcat ttattcactt
    12601 ccttaa
//
LOCUS       DAFLWC010000085        12431 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.087, whole genome shotgun sequence.
ACCESSION   DAFLWC010000085 DAFLWC010000000
VERSION     DAFLWC010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12431
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.087"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            17..2344
                     /locus_tag="L1V17_002311"
     CDS             17..2344
                     /locus_tag="L1V17_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBN1237051.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            2470..2799
                     /locus_tag="L1V17_002312"
     CDS             2470..2799
                     /locus_tag="L1V17_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HBN1237052.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            2839..3843
                     /locus_tag="L1V17_002313"
     CDS             2839..3843
                     /locus_tag="L1V17_002313"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBN1237053.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            3840..4286
                     /locus_tag="L1V17_002314"
     CDS             3840..4286
                     /locus_tag="L1V17_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HBN1237054.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            4436..5251
                     /locus_tag="L1V17_002315"
     CDS             4436..5251
                     /locus_tag="L1V17_002315"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBN1237055.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            5457..6629
                     /locus_tag="L1V17_002316"
     CDS             5457..6629
                     /locus_tag="L1V17_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBN1237056.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(6839..7285)
                     /locus_tag="L1V17_002317"
     CDS             complement(6839..7285)
                     /locus_tag="L1V17_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237057.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQQSA
                     AEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLS"
     gene            complement(7282..7476)
                     /locus_tag="L1V17_002318"
     CDS             complement(7282..7476)
                     /locus_tag="L1V17_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237058.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
     gene            7870..8292
                     /locus_tag="L1V17_002319"
     CDS             7870..8292
                     /locus_tag="L1V17_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1237059.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            complement(8458..9651)
                     /locus_tag="L1V17_002320"
     CDS             complement(8458..9651)
                     /locus_tag="L1V17_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1237060.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            9875..10252
                     /locus_tag="L1V17_002321"
     CDS             9875..10252
                     /locus_tag="L1V17_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBN1237061.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            10240..10578
                     /locus_tag="L1V17_002322"
     CDS             10240..10578
                     /locus_tag="L1V17_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1237062.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            10712..11155
                     /locus_tag="L1V17_002323"
     CDS             10712..11155
                     /locus_tag="L1V17_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HBN1237063.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            11417..12232
                     /locus_tag="L1V17_002324"
     CDS             11417..12232
                     /locus_tag="L1V17_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1237064.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            12242..>12431
                     /locus_tag="L1V17_002325"
     CDS             12242..>12431
                     /locus_tag="L1V17_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237065.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGC"
BASE COUNT         4217 a         2272 c         2430 g         3512 t
ORIGIN      
        1 tttattgaga ggagggatga aaatgattaa gaaaactcaa aataaaatcc aacgtatatg
       61 tcaaaaacat tttgtttcta gactcaaagc tgtatctaaa agaaaatact tacatcccat
      121 tatgatttcg atcatcttga tttttacttt cttagggagc ttatcaagta tttatgtaaa
      181 cgtttataca gaaacgtcaa attttgctaa ccaaacgaca gaggagacaa atagtccacc
      241 ctattctgaa atacagtcca tagaaagcac caatcagtct agcaacaacg agacaacctc
      301 aaccacatcc tcgactcaac tgattgatcc gacagaaaaa gaaatcacag cagcaaaagc
      361 agcaggggag aaagcttatt cagaaacagg tagaagccag acatttagta ctgttgcggc
      421 cactgcgaat ttcaacggac ataccatacc agatggatat acagtgatat atgccaaaga
      481 tggagtcatt gttgcggtta acggatcgat gagtgcggat aaaactgcgt tacaaggcgt
      541 aaccaaagca atcgctttta ttgataaccg tccagatatc cataatctgt ttattggctc
      601 cacagtaaat ggtactacta tcacattccc aaaaagtatc tatatggggg tggctaccgc
      661 tggaaatacg atcgattcag ttacacccaa tgcggataaa agttattctt ttacaccctc
      721 aacatgggga gggcttcctg ccggaggagg tatgagtact ttttcaatcg gtatacagtt
      781 agcaaatgat attccattca cggggtactc gatcaaaaat gggcagatcg ttgatggtaa
      841 gggaaatgtt tcaaattttc caacctatca agcagcaacg gttcaggtca atgcgaatcg
      901 gacaggaact ttttcttata cagtcaatgg tggagcagca aaaatcggaa cgtacgggac
      961 tacattatct ggaatccatg tgggtgacaa agtggttatc actccaacag cagtaacggg
     1021 ctattctttt gcacaaacaa acggttcttt cacagcccta gaaagtaacg tcgatacggt
     1081 gacctataca ggcaaacaaa caccaatcac tattaagtat caagactatt ttggacagat
     1141 gattgctcct tctaaaataa tgaatcttac ttacggaagt gctgcacaag acctgacgac
     1201 taatacgcct actatcaacg gatatacctt tacagctgtt tcagcgatag aaacaaagaa
     1261 ccaatcagca atgagtgttt tagctagttt agatacaaat ggaaatgtaa tcgtaaagga
     1321 cgcaaatgga aaacagattt ctgaagtcat cctatattat aagacaaatg caacagtatc
     1381 aatcaatgca aatggcagta agtactatga tggtctttct gttgtaccga tcgttaaata
     1441 tgcctttaat gataaaacag aatcaacatc ccttttaaac aatgatctca gtattgatca
     1501 aatcacatgg aatccaactg atttcaaagc gatgaatgaa aagggagttg aagtaactgc
     1561 gcctactgaa attggaacct atacgtcttg gcaattgaca aaaagcggac tagctaaact
     1621 agctgccaga acaaactatt tatttactat cgtgcagaca tctgatgtct atacgattaa
     1681 gcaaatcagc ggtgcggtag agctcagtgg cagtaagaca tatgatggaa aagcaggtgt
     1741 cccgtcaatc catgtcaagc tagcagaggg tgtcactagt tcgcttactc cagtacaagt
     1801 ggcacttagc agtatggatt acacagcaga tgcacaatca gcaaaaaata tggttaatgc
     1861 tggcagctat acaattaaac taacgaatag cggaatagac aaagtcaaag cagcaaatcc
     1921 caagttgtca tttactgata tagccaacac atcaggaact tataccatct ataaagctaa
     1981 cgcagtgatt actgtcgatg acgctgcctt taattatgat gcccaaagtc actcgatttc
     2041 ggttggaaat ctccacgtta ccggtgttgt cttaggcgaa tcattggatt ataccctaac
     2101 agttaacagc cggacagata ttggatcaca aatagtaacg attagtttag gcgaaggaag
     2161 tgtaaacaat aattatacga ttatcgcaac agataccgct aagttgacga tcaatccgac
     2221 tctcttgctt ccttcgacag gtgggatagg tctactgccc tttgtctttt taggactgat
     2281 ctttattttt tctggcttct tttattttat ccatcgtaag aaaaaagcag gtgaacagcg
     2341 atgaaaaaaa caaaaaatgt acgtgtggat atatttgctg ttctcttttt tatcctactg
     2401 gtctttttta taggttctcc gactgtgtca gctagagaat cacctattac atttactttg
     2461 cataatcgaa tgttcgaaag cgataagatg ccaagtatca gtcaaaacga cggaataaat
     2521 atcccggata actttcaagg agtaaaaggg ttgaacggcg ttactttcgc tatatatgat
     2581 gtctcggatg aattttacaa gctgcggtca gaaggaagta gtgtggaaga cgcacaaaga
     2641 aaactagcac aaaaaagtga tagtgaaaaa atactggcag aaaatgtgac aaaaacagta
     2701 gacgaggaag agggcattgc ttcttttagt gcatcggaca aagatgagca aggtcgtgac
     2761 gctgtttacc gatttacgga aataaagact tcagattaag taaaagaaaa atcagcacca
     2821 tttgtcgttg tgcttcctgt gacagattca tctaatcata aattgacgac catccacttg
     2881 tatccaaaga gcgaacaaaa aatacctgct gcactcacat taacaaaaac agtagagaat
     2941 aagcagacag attttgcaga tggggataaa gtcccttatc tcatcaccgt aacaattcct
     3001 gagaacatca acgagatagg aacctatacg atcaaagata cagctgatcc tcagttatgg
     3061 ctagaaccag aaacgatcga ttttttgatt ggtggagaca agattcatac atttcacaca
     3121 caaaaaataa aacatggttt tgtcttatca gattctggaa aagatcttag ttcgtttgct
     3181 ggaaaaaaat taacgatccg ttaccaaatg acattgaaag aaaacagtga aaaaacgaca
     3241 tttgataacg atgtacgttt gacgactgac aatcaaacag tagaaacaca tcttgccatc
     3301 caaacaggag gcaaacaatt tgtcaaagtg gatcggcaaa cgaaacaaaa actagcagat
     3361 gctcaatttc tagtcaaaaa aaatgaccaa tacttagcgc aagaaaacgg gataaatcat
     3421 tgggtagcca aagatgattc aagagcaacg atttttactt ccagtaaaga tggaacattt
     3481 tctgtccatg gattgtcttt tggaagttac gaactagtgg agattaaacc gcctaaagga
     3541 tatatattga gtcaatcaac cattctcttt gaagttgaaa aaggcagtta tgatccgctt
     3601 catcctatac cattggaaat catcaacgaa ccaaaagcaa atccgacgaa taatggaaaa
     3661 acgccagttc agatgcagac aaatggtcca tcaaatgaaa aaaatggagg aagctttcca
     3721 aaaacaagcg aagagatgct tggaggtttc tcaattttag ggttattgct agtcctttca
     3781 acagggacag cttggtttta taaaaaacaa caaaaaggaa acaataggag ggaaataaaa
     3841 tgaaaaacat caaaacaaaa atatggacgt ttttaggaac tgctatcatg ctgcttcctt
     3901 tcgttctcgg cctaggaact gcagaggttt ctgcagccgt atcacctaca ccagaaaatg
     3961 ttacggttaa tttgcataaa ttgaaattca cttcagcacc agaaaatcaa ataaacaacg
     4021 gaacggaatt gacatttccg aatagcgaac cgttgaacgg cgttgaattc aacgtatatg
     4081 acatcactgc tacgtactat ccaagtaaag acacagcagt tccagcagac gctacaccct
     4141 tcgcaagtgt aacgacttct ggtgaaggat tagctaacct gactcttcca ggtaaatctg
     4201 atgggaaaga tgctgtatac gtctttgtag aaacaccaaa gcccggtgtc gaaacgtcgc
     4261 caaatatcgt gttaagctta ccctagaccc tgacaaacct ttagacacga ttcacctata
     4321 tgctaaaaat gtcatcaaag aaagcaatat caaaatccag aaagctggga acttttcagg
     4381 ggtagataag ttagcagggg cgcaattcca gatcaaaaat tcagagaatc aattcgtgac
     4441 cggttttgat gaaaacactg gtgtcgctct ctatgatcct gctgagtcag cgttgacatt
     4501 cacaactgat actgaaggat ccatcagtgt caatggatta atagacggca attatacttt
     4561 agttgaaaca aaagcaccag atggttatca attaaccaat ccacaaaaag aaactacttt
     4621 tatagtaaaa aacggaaaat tgcaacaaac aaccggtatc atccatggcg cagatgaagc
     4681 caatcttggg aatccaaacg gtgtagtcaa tcgggaaaat acaactacgg ataacacgat
     4741 tactgtagaa aatgtccaaa actacggtga tttccacttc atcaaacaag atgtgaacac
     4801 gcaagaaaaa ttagccgatg cagaattttc tattctaaga gcaaaagatc caactgttaa
     4861 attaatgaaa aaaatagcaa accttgcctc aggagaatac ccatatgctt ggtcagatga
     4921 agtcacaggt tctgactggg aagaagtgaa attgatttct gattcagaag ggaaattttc
     4981 aatcgaaggg ctgaaacaag gggcatactg ccttcaagaa acaaaagcac cagaaggcta
     5041 cgcattacct aagaatgaag ctgcgtacac tgaatttaca gtagatgatg atccaacaac
     5101 ttctgatgaa acaacgatcg ataaccaacc taaaggaatc ttgccttcaa ctggtggtat
     5161 ggggatcatc gtattcatct tggtaggtac tgctttagtt ggaggagcag tgatctattt
     5221 caaaaaacgc catcaagaaa cagaagctta aactattgga aacaaaaatc atacgataaa
     5281 taaacgatag tgattcaaat ggggagaaag gttgtgacaa gtggtcggtc tcttggtatt
     5341 cgctcaacaa acggcaaaat aggaggaact attttgccgt ttgcttcgct aatactcagg
     5401 tcaaggcgct gatttcacaa cctcttcata tacatattag aaaataggtg gacatgatga
     5461 ataaaagcag aataagaata ctggacatct tcatggcaat cattttagtc gttgggatcg
     5521 ggatcttttc ttatcctttt gtagaagatt cactgaatga ttttcttgcc cagcaaatga
     5581 tcatccatta tcaaaagcaa gcatcgaata agaattcaga ggaaataaaa aaacagcagg
     5641 aaaaaatgac aaagaaaaac caacagttgg cagagcaaaa cgtatcacca gggataggca
     5701 gtttcaacca agcagttgat gcaaaagcat taaaagattt acctagtaat gcctttttta
     5761 tggaacatat gcttggagtc atcgaaatcc caaaaatcaa tgtcagctta cctatattcg
     5821 atcagacaac ggaaatattt ttgcaaaaag gaacgtcatt attggaagaa agttcttatc
     5881 cgactggcgg gaaaaacacc catgccgttc tttctgggca tcgtggactc ccagaagcaa
     5941 aattatttac agatttgcct aagttgaaaa aaggagacca gtttttcatc cagatcaatg
     6001 gaaagacatt ggcgtatcaa gtagaaaaaa tccaagtggt cttacctgat gaagtagatt
     6061 ctttgggtat ccaaaaaggc agagatctcg tgactttgct tacctgtact ccttatatgg
     6121 tcaatacaca tcgactgctt gtgacggggc atcgtattcc ttatcaagca aaagaggcaa
     6181 aaaaagcgat ccaaggaatt gatcaatgga aaaaatggaa attttttatt tggtttatcg
     6241 gtatactact tggatcaatc ggcttagttt ggctactcat cgcttattta gattctttgg
     6301 ccatcgctaa gcgaaactat cctttatctt tttatgtaaa gaacacaaac ggacgaccaa
     6361 tcgaaggaat ggtcttttct gtaaaaacgc tcaacggcaa acactatatt actagagaaa
     6421 aagttccatt tgtgaaagct tctgatgaat acggactagt gagattttct gatttaaaag
     6481 gcaggaacta tcgcttgcaa catgaggagc tcctgcttaa aatccatgta aaacataaac
     6541 attcgaaaca gttttcaatg aaattgaaaa aaggaagata taaactgcga aaagaaaaag
     6601 aggtgtacta tttgattgag aaagaatgaa tgaagatgtc caaaaaagca gagggaacag
     6661 actaaatgaa aaaagagaga agctgacgaa atggacgtgt aaactgttat ttttggttta
     6721 ctatctggaa cgccatcttc tattttttta tgtttcagaa gaattttatt attatagtat
     6781 aacttttgaa ttagtttcca taacatttgg agcaaggggt taaaccacga gcttgagctt
     6841 agcttaaagt ggcaggggta tacgtaccat ttccacattt atgtgtatgg tattttgaac
     6901 cggtcggtgt gacatagaca gtttgttcat tattttgctc aggagctgcg gcttgtgcct
     6961 gctgagaggc ctgttcagct gctgattgct gtcgcgcctg ttctgcttgt tgctgtgcga
     7021 ttgcttcttg cctcgcctgt tctgcttgtt gctgtgcgat tgcttcttgt tgcgcttgtt
     7081 ctgcttgttg tcgtgcaatt tcttcttgct ttttccgttc ttcttctgct tcttttgctt
     7141 tgattgtgga atcaattgca gcaagacggc ttgtcaactc ttgtttgttt tcaggtagcg
     7201 cttggatagc tgctgaagca gttgcatagt tttcttttgt aggatttgct tcagcttgtg
     7261 acaaagcaga ttccgcttct gtcacttttt ttctagtgca gctttttccg ctttttgttt
     7321 ctcttctttt ttcttttcaa tttgttcttg ttctttcgat gaatctgccg tactttcgga
     7381 gatcgtggta ctgctgctgg aagcctgatc tgaacttgtg ctttgagtag tagacgtagt
     7441 agcaccacac ccactcaaca aacttcctgc gaccaaaaac aatgcaacta attttttcgc
     7501 taaatttcct ccttaagtaa aaaacaaccg ttttcaataa atgtcctttt caattgttta
     7561 cttacttgtt ataataattg tgttatgaat agtgattgag gaaacttaat ctaatcccgt
     7621 gttgatacac gggatttttt gctatagttc tgttattaag tatgcaataa taaaatatgt
     7681 acgttatttt attattagat tattgacatt tatataataa acgattaaat gattcatatc
     7741 aatagaatac ttaggaaaaa aagagaaata ataacaggtt tatgcactat tgacggtgtg
     7801 acaatatgat atttgtatcc gtttttttct tgtatgtagt atagtaaagt agatacagga
     7861 ggagaaaata tgcagacttt tttaacaaaa gtttctcaaa agaaaattaa aatgattcat
     7921 ttactgcttg aaacagaacg ttggtgttca atagaagaac tacaaaacga attgaaggta
     7981 tcaagtaagt ctatcttgaa ttatctaaca gatttagaag aattgttcca aaaatatcct
     8041 gataaggtca ttttgaagaa tgagaataat cggcgctttt ctatggaaaa gcaggagaac
     8101 ttcccaatct acattattta tcttcatttc tacagaaaat catataatta tcatttgatt
     8161 gaattcatgt atcaacatcc tgagaaaaat ttggaagatt atgcagacgc tcaatatacg
     8221 agtgtatcca cagtttttcg ttatgctaag ttattagtaa agtactttga aatgacggac
     8281 gtcaaagaat agtcgccgcc agatagaagg aaattagcag ttgaaaaagc tgccctgcat
     8341 caagtaatac gaccagccaa acggaaacag tgtctcatgt ttttgatttg gctggtctta
     8401 ttaccgcaga tgcaagcttt tgccacacct ctttcttgtc atttacagac tcaactatca
     8461 atgctgcaag ctttccctta atgctgtaac accagtaaga gttgtcaaga ccagcagact
     8521 gactaggtaa ataccgctca aaaacaagat tacggcagtt aaactataat gatccatcaa
     8581 gaaaccgatg acgatagaag aaaaaccacc aacagctcgt ccaaggttca taatgaaatt
     8641 attcgccgtc gcgcggattt ctgttggata caaactacta atcactgcgc catatccacc
     8701 atacatgcca ttgataaagt agccgactat cacagcggct gctaccaaac tccactggct
     8761 atgggctaac acaagtagat agacagataa ggatgaacaa attaaaaaca aagaaaaggc
     8821 tagtttaggc cccaatttat ccatgattat gccaaaagtc atcatcccca aagacatgcc
     8881 taaaatagta ctgaccatcc acaatgaaga cccagaaacc gaaagcccta atcgattttg
     8941 cataattgaa ggcagccaat tcattaaccc aaaatagccg gcaatttgga cagttaccat
     9001 gatactaagg ccacatgttt gccaagcaag atgttttgat tcaaacagtc tgctaagttt
     9061 ggttttcttt tcggcagatt gtacagattt gaattccttt ggttcagtca agccgcgacg
     9121 aatgaacaag accatcaaca ccggcagtac acctacgaca tacaacatct tccaaccaaa
     9181 cgttggaatg atcacagcag ctaaaatcgc agccaaagcc gcaccgacct gcgcaccaat
     9241 accagcaacc gaagaagctc gtccaatttg tttttttgaa aaactttcgg aaatcaagga
     9301 catacacgcc ccgtattctc ctcccgctcc tacacctgcg ataaagcgaa agagataaac
     9361 caagtagatg tttgaagcaa aatacatcaa taaagaagca atcgaaaaca gaaggaccgt
     9421 ttgagaaaat actttcacac gtccatattt atcagctatg atgccaaaaa aaatacctcc
     9481 aatgagcatc cccaaattag tgatcgttga aatgaaaccc gcttgcgtac cactaatatg
     9541 aaaagaagta atcattgaag ataatgaaaa agctaaaaac ataatatcca tattctctaa
     9601 agcaattccc gccgatgtcg ataataatac ctttcgctga tacgttgtca tttttatacc
     9661 ccttttccta aaatttccct aaattgttaa aagtatatcc aaaaaagaat aaaaaaacaa
     9721 gactttttta tttgaaataa tacacaaaca accgatatag ataatccagc ttagttttaa
     9781 tagaaatgag tattgacttg gagtacactt aaagttgtag aataaataaa atacataagt
     9841 aaagtggcaa gaaattaaga gaaagagtga tcagatgaat atcaaacaag tcagtgaaga
     9901 aaagggcatt tcggccgata cattgcgcta ttatgaacga atcgggttga ttccaccagt
     9961 taatcggaca aaaggcggaa tccgtgatta tacagaagaa gacctaaaat gggtcgactt
    10021 tacgatctgt atgcgaaatg ccggattatc gatcgagtct ttgattgaat atattcgcct
    10081 atctagcgaa ggagaagcaa ctgtatttga gcggcgtaag cttttgattg aagaaagtga
    10141 acttttgacg aaagaaattg ctgaaatgca agagtgtttg gaacgtttac aaggaaaaat
    10201 caagaaatat gatcgtgtgt tatctagaaa taaaatggaa tgtatcaagt aaaaaaatca
    10261 aggagcatcg ctatggagtt acgcttacta aaatattttt ggacaattgc agaagaagga
    10321 acaatctctc aagccgcaga agttctacat cttacacaac caaccttaag ccgacaactg
    10381 aaggagttag aagaggaact aggaacagaa ctgtttgtac gcgaaaaccg caaaatgatc
    10441 ttgacagaag caggttattt tctaaaaaag ccgagcagaa gaaattttag atttaacgaa
    10501 tcaaaccact caagaattcg agaacagaaa aaaacaatta ttcagcggcc gatttacgat
    10561 cggctgtgtg gaagctgata attcgaatac attggcacta ttactagaaa agttgatccg
    10621 tgattatccc agcgttcaat ttcatatcca cagcggaaca agtgatgata tcacggagtg
    10681 actagaaaaa agcctgttag atttagcgat tttgctagat ccagtagata cagagaaata
    10741 cgaaacgatt ttgttaccaa gaaaggaaaa atggggattg ctcattttag aaaattctgt
    10801 tttagcaaaa aaagacgtga taacaaaaga agactttgcg aatgtacctc ttttgatctc
    10861 aaagcgtcca gaaatacagc gaatgtttgc tgactggtta ggcataaaaa aggagcagtt
    10921 gctgatcaca ggaacgtaca atttgatttt caatgtattt gcgctaattg agaatcaggt
    10981 aggtgctgct ttagtcatag aaggtgctgt aagtcatctt tcaaagcgag tgacattcgt
    11041 tccgcttgac ccaatgattg aaacgaactg catgctagtc tggaaaaaga atcggatttt
    11101 atcacctgta gtcaatgaat tgattcaccg tttcaaagaa gcttttgaac agtaataagt
    11161 atctctaatc gaagaaattt caatacaaaa gcgagacgta tgacagtctt gcttttgtat
    11221 tttttcattt ttaaatcaaa aaaaataaag agatttacat aacttgttaa ataagcgctt
    11281 acaaacataa gaagaacgga aatgaatcag ctataataac cgttgttctg gattgtaatc
    11341 attacaaaga aatgaagatt ataactttgg aggtgttcga aatgaaagaa aaaaagcaaa
    11401 aattcgttca aaaaacatgc cctttattca atggttgggt atgattctgc tgattgtatt
    11461 agctttattg acgatcattc cttttttatg gatggtttct gcttcattca aagcaaataa
    11521 tgaagtgttc acgattccga ttcaatggat ccctaaaact tggcatttag agaattatct
    11581 ggttatttgg tctcgtattc ctttagtgac attttttaag aatacagctt ttttaagcgt
    11641 tgtgatcacg ttgattcagt tgtttacttc tagttttgct gcttacgggt tttctaaact
    11701 aaattttaaa gggcgcgata ttttattttt agcatatatc ggcacgattg ctgtcccttg
    11761 gcagtcttat atgatcccgc agttcattat gatgagaaaa gtgggtttaa catatacgtt
    11821 gtggtcgttg gtgctattac aagcgttcaa tgcttttggt gtgttcttgt tgaagcaata
    11881 ctacagtagt atcccagatt ctttatgtga gagtgcgcgg atcgatggct tatcagagtg
    11941 gggaatctat cgcaagatca ttttacctct tacaaaaccg gcgattgcca gtttgacgat
    12001 catcacattc gttaatacat ggaacgatta tatggggcca ttcatttatt tgtcttctac
    12061 ggaaaataaa acaatccagt tagggttgaa aatgtttatt gggctatttg atgcagagta
    12121 cgcattaatc atggctgcct cagttgtttc tgttcttcct gttgctttta tatttttagc
    12181 gatgcaaaaa tattttgtag aagggatcgc ttcatcagga atgaaggaat aggaggtgat
    12241 tatgaaagag cagcgttttg acaaaaatgt ttatatggaa ttcttttatt ggttgtatca
    12301 atcattggca agtagccttt gtttttggtg tgtcaatatc ttgtatatag cagctgcgtt
    12361 ccttttgtcg atagatggaa ggaatgtctt ttcctttatt ttttctttac tttttattgg
    12421 tccaggttgc a
//
LOCUS       DAFLWC010000086        12359 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.088, whole genome shotgun sequence.
ACCESSION   DAFLWC010000086 DAFLWC010000000
VERSION     DAFLWC010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12359
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.088"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..465
                     /locus_tag="L1V17_002326"
     CDS             <1..465
                     /locus_tag="L1V17_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBN1237066.1"
                     /translation="WKMDETYIKIKGKWHYLYRAIDADGLTLDIWLRKKRDTQAAYAF
                     LKRLVKQFDEPKVVVTDKAPSIASAFKKLKEYGFYQGTEHRTIKYLNNLIEQDHRPVK
                     RRNKFYRSLRTASPTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLLGIPD"
     gene            complement(1081..2121)
                     /locus_tag="L1V17_002327"
     CDS             complement(1081..2121)
                     /locus_tag="L1V17_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBN1237067.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(2470..2796)
                     /locus_tag="L1V17_002328"
     CDS             complement(2470..2796)
                     /locus_tag="L1V17_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237068.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2783..3586)
                     /locus_tag="L1V17_002329"
     CDS             complement(2783..3586)
                     /locus_tag="L1V17_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBN1237069.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVD
                     IDPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAERE
                     FTQVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLK
                     GLIKLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKT
                     YIRRTITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3939..4229)
                     /locus_tag="L1V17_002330"
     CDS             complement(3939..4229)
                     /locus_tag="L1V17_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBN1237070.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(4365..4544)
                     /locus_tag="L1V17_002331"
     CDS             complement(4365..4544)
                     /locus_tag="L1V17_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237071.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(4541..4891)
                     /locus_tag="L1V17_002332"
     CDS             complement(4541..4891)
                     /locus_tag="L1V17_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237072.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(4884..6209)
                     /locus_tag="L1V17_002333"
     CDS             complement(4884..6209)
                     /locus_tag="L1V17_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBN1237073.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            6659..7273
                     /locus_tag="L1V17_002334"
     CDS             6659..7273
                     /locus_tag="L1V17_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1237074.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(7438..7680)
                     /locus_tag="L1V17_002335"
                     /pseudo
     CDS             complement(7438..7680)
                     /locus_tag="L1V17_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7884..9203)
                     /locus_tag="L1V17_002336"
     CDS             complement(7884..9203)
                     /locus_tag="L1V17_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HBN1237075.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
     gene            complement(9358..9945)
                     /locus_tag="L1V17_002337"
                     /pseudo
     CDS             complement(9358..9945)
                     /locus_tag="L1V17_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809248.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10583..10840)
                     /locus_tag="L1V17_002338"
     CDS             complement(10583..10840)
                     /locus_tag="L1V17_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBN1237076.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(10833..11102)
                     /locus_tag="L1V17_002339"
     CDS             complement(10833..11102)
                     /locus_tag="L1V17_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBN1237077.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(11233..11412)
                     /locus_tag="L1V17_002340"
     CDS             complement(11233..11412)
                     /locus_tag="L1V17_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237078.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            complement(11793..>12359)
                     /locus_tag="L1V17_002341"
     CDS             complement(11793..>12359)
                     /locus_tag="L1V17_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237079.1"
                     /translation="EEQLYLESETSQTKVTVSHNRLDVYKRRPETVKKGTELLRLETE
                     KYIMNVYLERSELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATID
                     DYYLVFTRFLTCGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTY
                     TYDDTEEIQNELDRKRMPYQRFERKKRQ"
BASE COUNT         3787 a         2257 c         1894 g         4421 t
ORIGIN      
        1 tggaaaatgg atgaaacgta catcaaaatt aaaggaaaat ggcattattt gtatcgagcc
       61 atcgatgcag atggtttaac cttggatatt tggttacgta aaaaacggga cacacaagca
      121 gcctatgctt ttcttaagcg gttagtgaag cagtttgatg aaccgaaggt tgtagtcaca
      181 gataaagcac catcaattgc tagtgccttt aagaaactaa aagaatacgg attttatcaa
      241 gggacagaac atcgtaccat taaatacctg aataatttga ttgaacaaga ccatcgtcca
      301 gtaaagagac gcaataaatt ctatcgaagt ttacgcactg cctcacccac gattaaaggc
      361 atggaagcca tccgaggatt atataagaaa acccgaaaag aaggcactct cttcgggttt
      421 tcggtctgta ctgaaatcaa ggtattattg ggaatcccag attaaatcat agataccgta
      481 agggatttta ttctttattt aaaactttgc aacagaaccg tccgttgcgg gtaataccgt
      541 aacactgaag ggcacgcatt aaggcgtcat cttaatgctt tcctgtagga cactgacgga
      601 gattaccagt ctcccgagcc ttacaggggc ctttcttttt tttgtatttt caattatcac
      661 aatttatcgt ccaaaagtgc agaacgaaaa tcaattcatc acaagcatat cagacaatta
      721 aatttaaaac aactaaaaat atacaaaaaa gtgtaattga atattagcag cactgcctga
      781 aaagaagtaa tatcaggctt ttcagcttgg ggaaataagt gaattacctc tcttcatgaa
      841 ttattataac tcaaaaaagc acatatgcaa acactagttc cctatttttt tgaatgaaaa
      901 ataactaaaa tatctaacga ttatgacttt aaaacctacg tttgcgattg ttttcataaa
      961 cttttaatct aaaaactccg gaataatagc tatttatttg taacatttgt aataaaatta
     1021 aaatcataaa aaagttctaa tttaaaattg atcattttta tagtgatcgc tttttatcaa
     1081 ctactctagc caattttccg tactaactgt tggtaattcg ttaaatgttt ctctttgttc
     1141 gtttgcaagc tttgccgcaa tagctttttc gacaaaccaa ttttttacat aaacgaaaat
     1201 tagattctgc aaattgttta ctttttcagt tttttgtttt tgataagctt tcagcaaagt
     1261 catatataat cctttgtcag catcaattcc ataagattcc agttcttcat aaacaacaac
     1321 tgtttgctct aattcttcag cttttttctt tgcattatga atagtttgga cggttttttg
     1381 agcgtcttcg taagtactag aaaatgtttt tatcaagttt aatacatttt ctggtacaaa
     1441 tgtatttata ctgtcctctt tcatgatgtc gacgaagtta tctagtaaaa cttgattttg
     1501 taactgatca gtttcagtgt ctattatgtg tctattagtg tctatagaat tagaatagaa
     1561 tagattgtct gcgattttcg caattacggt tgagtccttg atatgactgg attttgccgt
     1621 atttgcgatt ttcgcaatta cggtggtatc attgatttct cgcggttttg ccgtatttgc
     1681 gattttcgca attacggtgg tatcagtatt gtcttcctct tccatgattt taaagacgtc
     1741 ttgattcgtt acttctggct tgcctaagta caataaatta ggcatggatt caatcttacc
     1801 gtcacgttta tttactcttc ctctcttctg tttcagaaga cctgcttttt ctaattcctt
     1861 tttgatttta gatactttac cttcgcggca ttgtaacaat ttcattaatt cttcaactgt
     1921 gaatatgaaa aatatattat catcagaatc tacccagtta tttttgactg aataatcaaa
     1981 tcgatcttta agtagcatat aagcaatttt tgcatcattt gatagatcca tgtatttttc
     2041 gttagtaaaa aataccttag gcatttgata atatttttca cgataaattt cttttgattt
     2101 gtaataatta aaatcattca tagccaatcc tctttctgta ggatagcgtt ttgttcaaaa
     2161 ctatgttaca atgaattaaa caaatatatc tatccactat atatttttct actgctgata
     2221 agtcgccaaa ctttgttaaa gcagtagtct ttttttatct ttttttagtt taccttaaaa
     2281 aataaattaa agcaaaccgc tctatttcaa ggtttaagct catagtaact atatcacgat
     2341 attacaataa tattatatca cgatatcgta atattacaat atgaagataa gcgacttatc
     2401 agctttgata ctactgattt ttataaaaaa aatatcacga tattatgata tcgtgatatt
     2461 gaatgtaaat taaattttat tttgtttctt tgctagttta tatccttcaa tcaagtattc
     2521 ttcaggtatg gactttaata gcgcatcttc tataacgtct ggtttacttt tgtctgattc
     2581 agcaatagtc gtccaatatt tgagtgctga cattagaatt ggatttatac gaatgctatc
     2641 tgctgttctt acactacttc cttgatcttt tatgacttta cttatatttt tcttggttaa
     2701 ttcgatttct tctacttctt ttgatttaaa attcttttta tttttatttc ctagtaatct
     2761 acttactgca gcttgactgc gattatcttc tgccatcaaa atcaccaact tcttttaaat
     2821 attcttctgt aaatgcttta tagtcatctt cagctgttga gggtttatta aaattgatta
     2881 gatctgatcc agcagcttgc gcttcgtcaa cggttattgt cctacgaata taagttttga
     2941 aaatttttgc accaatgact ctagaaattt cggttgctgc agacgtcatt tctttagaaa
     3001 tgttataacg cttattatac ttagtaaata gaactcctcg tacttcaagc ttgtcgttcg
     3061 tatattcttt taccgtttca atagtttcac ttaactttat tagtcctttt aatgagaaat
     3121 acgcagcttc aactggaatg ataatttcat cagaaacagt aaatgcgttg actgtaagca
     3181 ttcctaaact tggtggacaa tcaattataa tataatcata gttgtccttg attggttgaa
     3241 gtactctttt aagcctgtgt tcacttccta cttgagtaaa ttccctctct gcagaagaaa
     3301 gggctatgtc ggctggcaaa acatcaattc ctttatagtc cagaatagca tctgtaatgt
     3361 cagcctcccc ttttaatact tcataaattg taggttggtt tgttccatct atatcgaaac
     3421 ctacattatc tgtagcattt ccctgaggat caatgtccac taaaagtaca tttttaccgt
     3481 aaacaaattt caaacatgct gctaaattaa cgctagtcgt agttttagaa actccacctt
     3541 tttgattggc tactgacaat attcttgcca ttaaaatatc ccccattcat cttatattat
     3601 aatataatta tatcataata ttgtgatatt gcaatatcgt atatgcatta tattgtaata
     3661 ttgtgtgatt attttgtttt aaagatatat atcggttcgg atataaagat tattcatatg
     3721 ttattcgaaa ttaaaataat cactttttat tactttaaaa ttttttatta atgataagaa
     3781 atatgttttg cgagcagcaa ctagaataat ttaaacatta ctaaactgtc tatattgtta
     3841 ctaataattc ccttcttata gtgcattttc ttagaaaaaa acaatattac gatatcatga
     3901 tattaagata tcgtaatatt atacaattgt gattgatatt atatatgttt ttttattttt
     3961 ttatcatgtt taatcttgaa ggaatcatat tctttttcta aagacaggag cttttcataa
     4021 acatcagaca tgtttaaact agaggccagg cttaaatcat aaacgaatga agcaggtaat
     4081 gattttattc tacgttgtcg ggttatccag cttgcaaccg ttccttgtgg gtaggcatat
     4141 aactcacaaa attgttctac agtgattcct aaattcttga taatgtaaac attgatcggg
     4201 tgcgagtaaa caaatgtatt gatagacatg gtgcgtaagc ctactttctt ttattattgc
     4261 gtttgcaata atagtttaac acacgcatta ttctagtatc tactcctatt tgtaaaaaca
     4321 aaaaaggatt catagagata actctataga atccgtaaaa taccttatat atataacggg
     4381 aagatataaa acctaaaatt atgataacct gctgcagctt ctacatagaa agagaagcgc
     4441 tcaacaccaa cctcatttat caaacgttgg ccataacccc aaatctcttc tgatagctga
     4501 tcaaaggtta tatactttag ctcatattgc tggataatgt tcattctaat cgactccatt
     4561 tattatcctg gtaaaattcg atatgacgta tttcgtcgta gtgaattttg tcttttccaa
     4621 cgtagatccc cagctcatca ctacctaaga tcttgccaat gatatcttct ggatagtatc
     4681 cttcagcgtt tcgttcttct ttttgaatag atactgatct attttttatg actgcagcgt
     4741 tcaatacttc cgcaatctct tcagtcgtca tttgttcttt tgctaaattt tgactggttc
     4801 gttgttcatt gtcggcatca atttcttcag tatgatcaga taaataaaac cctgcccact
     4861 ttaaacgtcc acgatcattg taatcaatca tttttaattc ccccatttcc gcccgcatga
     4921 ccaccaacaa gtgtgcttct agtaatgctt ctagcgcctt ctaacattga agaagcatgt
     4981 acaatcgacg taaaaccata tttttgccga atcttgtcaa taattttatc taaattttct
     5041 tcgtcaattt gcttttgtgg atcactaaat aaatccagct gaagcgaatc ggtgtacaca
     5101 agcttgctat aggttattcc aacatgcctt acttcttgtc cttcataata cttatcaaac
     5161 aagaaaagac aataattctg caattccttt gtattatctg tgatagggat cttcatctgg
     5221 tgtgaaaacc ctggtctcgt ttctaagatc gacgtgccaa tgtgtaaatg gacacaacct
     5281 gttttacagt tatgctgcct aatgcgtatc gctacttgtt ccgccatttc ttttaccacc
     5341 agctcgattt catttcttct agtataatct cgtggtaaca cttgtgaatt tccatatgat
     5401 ttttcctttg tcggttctgg tgggattgct atatctgttc gatcgatccc attagcatgg
     5461 aagtacagct gtaagccaat cacacctagt ctattcttaa tcgtataagg attccagtta
     5521 gcaagatctc taatgctcat aatccccatc tgattgagtc tttttttcat tcgagagcca
     5581 attccccaaa agtccgtcat ttcaggaata ttccatactt tttcaggaac gttttcgtac
     5641 gtccattccg caacaaatcc ttcattatgc tttgcttcgt tgtctaaggc tagtttagcc
     5701 aaaaggggat tatctccgac acctactgta gcaatcaatc ctagctcttc tttaatattc
     5761 tcctggatca tttgagccag cttctttctc cgttgacttc gtgttccttc agtcgtaaaa
     5821 agattcagtg atcgggtcac ttttaagatt gattcatcga tcgagtaaat cagtagatct
     5881 tcatcagcca catatcttct gaaaatatta tttacctgca tatttcgctt gatatatagg
     5941 ttcatacgtg gtggaacaac gtgtagtgtt ttaggaaatg gttgtggtaa gtcacgtggt
     6001 ctactcacat ttgtaatacc ataccgcttt tttgcttcag gagaagaagc taatatcaat
     6061 cctgaaccag tattatcagc tcgactcata acaacaagtt ctgttgttaa tggatctaaa
     6121 tttctttcta tacattcgac acttgcgtaa aagcttttca tatcgattaa aaagtaatca
     6181 tttactggct cttttgaata atccatcata aataacactc cattctttca cattatacaa
     6241 acatatgttc gatattgtaa agaagaaata gctaaataca taaaaaaaga agcataggta
     6301 tgctatcacc ctgcttcttc ttttgatttg tatgatcaat ttattctatc actttactaa
     6361 ttaatttgaa aatctaataa aaactctcac tctaaaagag tgagagactg caaattagag
     6421 tacggacttt tttggagttc cgttctttaa tattaacaaa tgaataaaat ccttacaaca
     6481 tttgagaata agttatcagt agacacttac aaaaaattct catactattt cctccatcat
     6541 tagtttttgt ctatataagg tttaccctaa atagacactg gtataacatt gaaaaatatg
     6601 gcttcctcgt gtatgattag ggtgtatttt aaatagttgc agaaagtagg taaaagtttt
     6661 gagagttgca tacatacgtg tctcatcgat cgatcaaaat gaacaacgcc agattgaaga
     6721 aatgaaaaaa ttcggtgcag agagaatttt catcgagaaa caatctggcg caacgattac
     6781 tcatcgacct gttttccaag aagcattaga ttacgtccga gatcaagata tttttattgt
     6841 ggaagctatt gatcgacttg gaagaaatta tgacgagatc atcgcttcag tcaattactt
     6901 gaagaagaaa aatgtgaagc tgatcattac tagtttaccg atcatggctg aagcaattgg
     6961 caatcctctc ctggataaat tcattaagga tctgatcatc caaattttgg ccatgatcgc
     7021 tgaacaagaa cggactgaat cgaaacgtcg ccaggcacaa ggaattaaga tcgcaaaagc
     7081 aaacggcgtc tacaaagggc ggcccaaatt atacagtgca gacgcaaaag atccccaacg
     7141 tcgccttgtt tacaaaagca tcgttgaaga tcttaaaaat ggtgttgcga ttgctaagat
     7201 tgctaaagac tacaatgtta cgagacaaac cgtgtataga ataaaaaaag acagcatggt
     7261 caatgacaaa tagttgatca tgctgctttt attatcttct catctttaat ttcctacata
     7321 taattactat ctataaaatt aagtcttact cagaacagat aaagcataaa attccaacaa
     7381 accatttttt acttaactaa ataaagagtc tgttaatata atcttcactt atttacgtta
     7441 atcccctact gtatttgttg gttccttatc tatattttct acaaaatcct tattatcttg
     7501 tgatttagct tcgtataatt ctttgtatgt cgacacattg gttatactaa ttcctatagc
     7561 tagttcttga gactctactt ttctctctag ctcctttgac aaagtgattt gagatttatt
     7621 tggttccgtt ggagtcaatt ctatagattc ttcataaaaa tctctataca taaagctatc
     7681 cctgaataat tcatagcttt aattctttgg cacattttat tgaaatatgt atcactaata
     7741 tccctatcaa ctgattttga ctaaaaagtt acttcaaaca ttcactgttc aaaaatattg
     7801 aggaataaat tttgggtgta aggcattttg agcatacttc tccctggata acttcccagt
     7861 aaaaaaatcg ttagattgtt ggattagatc cattgactgg ctcgcctcag gcgagcaaag
     7921 accctgtaga attcattctg atacacatga taactagata atttgagata gactcgtcta
     7981 cccgtttgga ctaatttccc agcaactttc agaaacttca atcgaataga atgaatggtc
     8041 attccctttt ggacttcttc aaagccaatc gttcttaaga agttgactaa gttgtaagct
     8101 atcaagctga gcatcattcg gacatgattc tccaaaaagc gaggactgtc tgttttgtca
     8161 aagtaaaagc cagctttcgc ttctttaatg aagttctcca ttgtgccacg tttggcatag
     8221 atagaaaaga tggtatcagg agaaacattt tctgatagat tcgtcacgat aaattcatgt
     8281 cgaaagagta gttcgcccgc ttcacgtgtt gagcgtatac acacgcgacg actttgtgac
     8341 caggattgtg cttgataagt ggtcgagaag tactgaactt ctcgttcttc ccacttttga
     8401 ttatcgccat aaagtactga tttctcagct atttgaccta gtctacgatt attcttcagt
     8461 cgaataacat aatgactctt ttttgattca cacgaatcat acacaccagg tgtagcgaac
     8521 ccgctgtctc cacgaaccaa gatgtcagtg tttggtagag agtgattata gtgctctaat
     8581 aaaggtgtga gaaactcctt tacgcctttt gatgtatatt gatttcctga acgtagttca
     8641 gcttttaaga agtcaccagt caatccgtca aaagctacca atggatggta accataggtt
     8701 tggtagtgtg tattataatt cgtttgttct tggtgaccaa atgtatctga atgggtcgaa
     8761 tctaaatcaa tgattaattc cgtatcatta cggatgaggc gtgctttatc gataagttct
     8821 tggttcaaag cttgaagttc atggatattc tcctcagata gtcgatctaa aaatcgggaa
     8881 agtgaagatt gagaagcgag ttctttccta tctaaaacag ctttaaacac aggatcttgt
     8941 ctcaggagat tagctgcaga atcagctgag taaccagcaa ttaattgcat aatgaactgc
     9001 tcaagtatgg ataagttgtc atgagtaaaa tacgctcgtt cgtcttcaat gtgaatgtgt
     9061 tgcttagcca gttcagaaaa accaaagatg ttcatcagct ctttcactag gacgagaccc
     9121 gaatcactcg ataattgacc acctgtatga gaaatagtga tatttgaatt gaattttact
     9181 tggtttttgt gtaagctagt catgaaaaga actcctttct tttggttggt ttagtcactt
     9241 taaccatagc agaaaggggt tcttttttca tcacttaacg ggtgaagatg aaaaagtaat
     9301 tgtaagctgc cgtgaggcag tttcacatgg ttttaattaa aagtatgaat tattcaggct
     9361 atcattaatt ttataaaaaa aattaaatgt ttttagcact gccatataac attcaaaaca
     9421 ttcttctata gttggtttac ttccttgagg agaatgaacc aatttattac gtttttctat
     9481 gaaattttta atttcctttc ttatttcttt cggaaactca atattaaagt accctttaaa
     9541 catgctccct aataatttgt ctacaggggg agattgtaaa ttctcaaata ttagagttaa
     9601 atcaggtttc tcttgttgat aaaattcctt tacccctatt tcacaggctg taattatcga
     9661 aataaaccta tctctagtat ttgatatatt tttacttctt ttaaggagta taagagaaaa
     9721 ggggatactt tcgtgtccat gcatgtaatt aactaattgt tgagcttcag aagttatatc
     9781 tctaattata tagttaacgg aattaggaag tgtctttaac tctaatgaaa tttctatcca
     9841 attactatct tctaatctgt atatgctcga agtataattt gattcgtcag caagcatcgc
     9901 tacatcccaa acactgatca taaaatcttt taaacgttca atcatttcag caatattgct
     9961 aaaatcagct aatttttctt tagaataaaa aaaaacattt atatcagaat caataaattc
    10021 tattttttta ttactatatc gtcatcatta tcttgaccat ttatgtttat tgttccctga
    10081 gtggggagta cttctttcaa attcaagtta aatttatatt ccattacttc tcctccaata
    10141 tataaaaatt acttaactgt atccaaattt aatatgtaaa taaatcatta atttttagct
    10201 aaattctatg agaagtttat ttttgttgtt tttgctaatt aactaaaact agtacaaaaa
    10261 atttaaaata gattattaaa cctattgctt attctattca gtcatatata taagcgtcat
    10321 cctttagtaa ctaacatccc acactacaat agtattataa catatctatt caacttcaaa
    10381 ttgttgaaat ttaagccatt tatatttact tttcctcaac tttagaaatg attttactaa
    10441 ccttatatcc gtaatacgcg taacaaacac attcattaat aacaatcaac actaagctat
    10501 attagctttt taaatgacta gggtaaataa aataaggatc aaaaactttt aagtttctga
    10561 ccctttcctt acttccgatt ggttaatagt gatcttttgc agaataaata aatatcgttt
    10621 cattttcaac tctatatatc agtctatgtt catctgtaat tcttctggac cattttccag
    10681 ataaatcatg ctttaatggc tcaggttttc ctaatccagc aaagggggaa cgatcgatat
    10741 cttttattaa cttgttaatc ttttttatat tgcttttgtt tccttgctca tgccaataaa
    10801 gataatcatc ccaagcatca tcagaccaag ccttaatcat cagattcaac ctcgattaag
    10861 tcatgtgttt taaatgcacc tttggagaat tgttcatctc ctcgacgaat tttttccatg
    10921 acgtaattat tagaaagtgt tctcaacgtt tcttgcatag aatcataatc tctttttgat
    10981 aatacaacaa ctgtatcttc tacatcttta cttgttacaa taagtgtttc agcatcctca
    11041 ttaacttgtt tcatataact acgtaaattt tggcggaaat ttgaataagc tactgcttcc
    11101 attcctttca ccccttattt atttctataa aacaattgta cattatattg tacaattaag
    11161 caaatgatta atattctaac ttcttataat taaaagtgct atcactttta gtttttagga
    11221 taaaaagtga cgtcactttt tgagtgctgg tacctcaaat cctgcttttt cttgggcaat
    11281 caataaatct aacgcaatac acataatcct ggattcactt ttgccgtact tctgctttag
    11341 ttgctgcaat tctttttgtc tcttttcatc caacgtaacg ggtaaccgtt tatttcctat
    11401 tgcaattggc attagtactc tctcctttca tcgaaataac cctatgaaaa atatggctgc
    11461 aatcatcttg aatagtagac tcacaagggc taatacaaag cgccaaaaga tcaaacaaaa
    11521 taccagtatt gccaaaaata ctacgaagtt taaatgcaca gctgcagcat ggcgcataag
    11581 tatttcgcca acaaatagga ctaacaatag aggaatgatt ttattcatat ggatctcctt
    11641 ctttctctta ggttatcggg tgttgcccgc ttatttcgca ccacctaagc ggcgggggcg
    11701 gttggagcga ttggtgcgaa ataagaacca ttcccttagt tactaggttt tttgtcctta
    11761 tttcacacat tctcactttt cggtataaat gattattgcc tttttttcct ttcaaatcgt
    11821 tgatatggca ttcgtttacg gtcaagttca ttttggattt cttctgtatc gtcgtaagta
    11881 taggtgtcta aaaaatcagt taaagtcgtg taccagtcgt cgcctgggtt atctacttct
    11941 tctacatatt ccctcaaaaa tgcttcgggt acagcgagtt cataatccat tcccattaac
    12001 acgatagatt ccgttccaca cgtcaaaaat ctagtaaata caaggtaata atcgtctatc
    12061 gtcgcatctt tgctgtttag ctcttccatt tcttcttcca ttaattccat gctctcaaaa
    12121 attgaataat attctgattc tgagtaatag tgtttcctgc aaatcgtgta gctgacaaag
    12181 ttttcgacca gctcactcct ttctaggtaa acattcatga tgtatttttc tgtttctagt
    12241 cgtagaagct ccgttccttt ttttaccgtt tcaggacgac gtttatacac gtctaaacga
    12301 ttatggctga ctgtgacctt cgtttgactc gtttcacttt ccaaatacaa ttgttcttc
//
LOCUS       DAFLWC010000087        12207 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.089, whole genome shotgun sequence.
ACCESSION   DAFLWC010000087 DAFLWC010000000
VERSION     DAFLWC010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12207
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.089"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(169..333)
                     /locus_tag="L1V17_002342"
     CDS             complement(169..333)
                     /locus_tag="L1V17_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237080.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            628..1956
                     /locus_tag="L1V17_002343"
     CDS             628..1956
                     /locus_tag="L1V17_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HBN1237081.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            2158..2991
                     /locus_tag="L1V17_002344"
     CDS             2158..2991
                     /locus_tag="L1V17_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HBN1237082.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            3007..3744
                     /locus_tag="L1V17_002345"
     CDS             3007..3744
                     /locus_tag="L1V17_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HBN1237083.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(3899..4867)
                     /locus_tag="L1V17_002346"
     CDS             complement(3899..4867)
                     /locus_tag="L1V17_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBN1237084.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            5099..5932
                     /locus_tag="L1V17_002347"
     CDS             5099..5932
                     /locus_tag="L1V17_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HBN1237085.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            5966..6805
                     /locus_tag="L1V17_002348"
     CDS             5966..6805
                     /locus_tag="L1V17_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1237086.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            6831..7391
                     /locus_tag="L1V17_002349"
     CDS             6831..7391
                     /locus_tag="L1V17_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBN1237087.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            7590..9311
                     /locus_tag="L1V17_002350"
     CDS             7590..9311
                     /locus_tag="L1V17_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HBN1237088.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            9476..10618
                     /locus_tag="L1V17_002351"
     CDS             9476..10618
                     /locus_tag="L1V17_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBN1237089.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            10634..11845
                     /gene="thiI"
                     /locus_tag="L1V17_002352"
     CDS             10634..11845
                     /gene="thiI"
                     /locus_tag="L1V17_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBN1237090.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
BASE COUNT         4156 a         2049 c         2538 g         3464 t
ORIGIN      
        1 gatgtcgtag gttcgagtcc tactgccgga gtaaataaag cttatgcaaa gaaaaagaaa
       61 tccaatcact tgggtttctt tttcttttat tattatgatg aatcaagctt tctgtttttg
      121 tcacgtatgt tgtaatcttt acgaaagagt agagttggct actcataatc aaccatactt
      181 cccatcatcg ctaaatacga aataaatcag cattcctaca ccaatcaaag cacaagctgc
      241 accaagaaaa gggatgacat tcccaaagtt atctgtattc ataagtatgc caccacccac
      301 aaacaaaaag ccgccagcaa tcaggttttt cattttattc atctcctttc ttacgttata
      361 gtatttcctt ctttcaatga gtattttgaa agctatctta ttgtatgatg ttcttctagg
      421 cctcttcttt attatacagg ccattttcgt tatctcatag aaatattcct ttttatctga
      481 aaactattgt ataccgtatg acatttttct tcatgaagtt gtaagtatat tctcattcaa
      541 atgaaaattt catcatagaa gagattgtat ttctaaattc ttaagagtaa aatacgaagt
      601 ataacttgga tttggaagga tgattggatg aaagctatta cgcctgatat gacaacaaaa
      661 tttaacaaac agtttcaagc aaatatcaaa cagcaggcat tgcagcgggc agttgtgaag
      721 aacggaatta ctgcttctgc tgaaaatgtt tcagcacatg tggagaatac accggtattt
      781 tctatagatt tggctacggg gaaagtggct aatcaaatgc aatcggggcg ttgctggatg
      841 tttgctgcac tgaacacatt ccgtcataag atgctgaatc aattccattt aaaagagttt
      901 gaattatcac aaaattacac ttttttctgg gataaatatg aaaaggcaaa ttatttctat
      961 gaaaacatca ttgcaacagg aaaagaggca atcgatagcc ggaaagtagc tttcttactc
     1021 gctactcctc aacaagatgg cggccaatgg gatatgatcg tttcattatt ccaaaaatat
     1081 ggcgttgtgc ctaaatcggt gatgccggaa agtgcgaata gttcaaattc tcgagatttg
     1141 aataactact tgaacaaatt actgcgtaaa gatgcagtag tgttacggaa aatggttgct
     1201 caaggagaaa cattagacgc tattgaagaa aagaaagaag aaatgctaga aagcatttat
     1261 aacttcttag ctatctcatt aggaacacct ccaaaagaat tcgattttga gtaccgcgat
     1321 gaagaaaaga actatcatct tgaccgagga ctgacaccac aaatttttta tgataaatac
     1381 atcggtgtaa aattagatga ttatgttagc gtgatcaatg caccaacaaa agacaaacca
     1441 ttcaatcgtt cttatacagt agagatgcta ggaaatgtcg ttggcgggaa agaagtcaaa
     1501 tatctgaatg ttgatatgga aactttcaaa aaattagcga ttgctcagct tgaagaagga
     1561 gaatctgttt ggtttggttg tgatgtaggt caatcttcta ctagaactag tggcatcatg
     1621 gccttagatg cttattcaat ggatgatcta tttgatacgg attttacaat gactaaagct
     1681 gaacgtttag attttggaga aagtctgatg acccatgcga tggtattgac cggtgttgac
     1741 ttagtagacg ggcaatcaac aaaatggaaa gtcgaaaata gctggggcga aaaagttgga
     1801 aagaatggct tctttgttat gagtgatgcc tggatggacg aatatacgta ccaaatcgtt
     1861 gtaagaaaag atttattgac gaaagagcaa ttaaatgcgt tcaatgaaga accaattgtt
     1921 ctatctccgt gggatccaat gggtgcttta gcatagacga gtatttcaat gaagagtatg
     1981 tagtaaagat aaaaagagct ggcttaagcc agctcttttt atctttaaag tccattccct
     2041 gttttttatg gtccctgtgc tataattcta aataaaggat aaggattgga aataatcctt
     2101 ttatcattaa aaatatgatg acgaagtaga ataaaattgg gagtaggggg gaaagtcatg
     2161 gatatccaaa ctgttttatc tgatctgaaa ttaaatggta aagtgattcc agttgttggt
     2221 ggcgatgtta atcagaccta tcgtataaaa accgaacatc gtgcttattt tttaaaaatc
     2281 catccgaatg taaaaaaagg attttttgaa gcagaagtag acggattaaa agaactgtca
     2341 gcattcgtac gtgtaccgga tacgtatatg ctaggtgaaa caagtgaagg cgcttatttg
     2401 ttaatggaat ggatcgagcc gggaaaaggg gatcaacgag atcttgctgc agctttagct
     2461 aatctccatc agcaaacagc gccacaattt ggttttcgta aagataacta tttgggtaca
     2521 cttgttcaga aaaattcttt tgaagaagat tggtggactt ttttctttaa agatcggctt
     2581 gaatcccaga tttctttggc agaagaaacg aatcgatgga atgtacagcg tcaagaaaag
     2641 tatctgcgat ttaaagaacg tgtattgaaa tcggttgaac caaaaaagat cactccacgc
     2701 ctcttgcacg gagacctgtg gagtggtaat gtgttctttg accagcaagg gcatccagtt
     2761 tttgtcgacc cagctgtttc ttatgggaat cgggaacaag atattgcaat gagccagtta
     2821 ttcggtggtt tccgaccgga atttttagat gcttatcaaa ctatatttcc attagaaaag
     2881 ggatggaaag accgactgcc gatttaccag ttatattatc ttttggcaca tttgaatatg
     2941 tttggagaaa gttacggttc ccaagtagat caattactag aaaattttta agaggagggc
     3001 gtgtttttgg caaaaaaata taccaaaaag catgaagttt catattatga gtgtgacatc
     3061 aaccaaacga tgacatttcc ttcgatgtta ggagtagtta tcaaaacgtc tgaagatcaa
     3121 agcgaccagt tgggaagagg cagtgaattc gtcaatagct ttggacttac ttgggtcatc
     3181 acgaattatt ccatggagat taatcgtctc cctagagtcg gtgaagtaat ctcagtaacg
     3241 actcaagcca tggagtacaa taagtttttc tgttatcgga acttctggat ccatgatgaa
     3301 gatgggaaag aattagtcaa aatagaatct gttttcgtat tgatggattt tgtgaatcga
     3361 aaaatgagca gtgttaatga agagatcatt gctccttttg agagtgagaa gatcaagaaa
     3421 atcaagcgtc aggaaaaaat tgaaaagatt gattcgggct tcatgttgcc atatcgtgtt
     3481 cgtttttatg atatcgatag taatcagcat gttaataatg cgatgtattt taattggatc
     3541 attgacgtat taggatatga ctttttgact acgcatgttc cagaaaaagt aattattcga
     3601 tttgataaag aagtagagta cgggaatgag atcgaaagcc attttgaaca aatccctatc
     3661 gaaaatggtg tcaaaacaaa acatgaaatc cgaatgcaag aacagctgta ttgtgaagca
     3721 aatattatat ggaaaaataa ataaaaaaga ggttgtgaca gaagggggca acttcaagaa
     3781 ataagaagaa atttacgaaa attgtttctc aaatttttgt aaattttcga cttagttttc
     3841 gaagaagcta tttttgtcac agcctctctt tttaagttta gctattagat aatgatgttt
     3901 agttttggat aaacgaaatc aattcttcac ccgacaaacc atagtttaca gcaatcaata
     3961 gttttaaacg tgctttttga ctattaatac tgttacagaa aataatcccc attttttcta
     4021 gttcttttcc cccgccttca taatcataaa caggctctgc gattccattg aaacaacgag
     4081 aaacaagtac tacagggatt ttttggacaa gaagcttttc caaagcagct aaggcttgtg
     4141 gagggagatt ccccgcacct aaagcttcga ttaccaaacc gtctactttc gtatgggcga
     4201 tggcttccaa taagtcccct tgcatcccag catatgcttt aacgatcggg atagtcccat
     4261 ctacagcgga aatgtccagt cgctttgttt ctaaaagttc ctgcaagaat aaaattcgat
     4321 tcttagttac taagccgatg ggacccaatg taggtgttcg gaaagtagca acatttgtgg
     4381 tatgggtctt tgtcacgtag cgtgcagaat ggatctcatc gttcatgacc accaaaaccc
     4441 ccttatctag cgcttcttca caacttgcga cacgaatcgc actttcaaaa ttataaaggc
     4501 cgtcacttcc aagttcatta cttgaacgca ttgccccagt caaaacaatt ggtaatttgt
     4561 tgccaatcgt tgtatcaaga aaaaaagcag tttcttctaa tgtatctgta ccgtgtgtga
     4621 tcaccactcc ggatatacct gatgcataag cggacaagat acgttctttt aataccaaca
     4681 tgtgagaagg catgatgtgt ggtgagggaa gattgaagat atcttcaact aataattcta
     4741 catgcttggg gattgtgatt tctgcatcta ataatgggtt tgccacatca ggactaacac
     4801 cgcccgtgag catgttttct ttcatggcga tcgttccgcc ggtgtgtagt acaagtattt
     4861 ttttcatttt acagacttcc ttacgaataa ttttgcatag ccgttaaatc ttattgtata
     4921 ctatataaaa gagttttgct atcagtgaag aataacgaat agcctaactt atcataaaaa
     4981 agctgacctt attaaaatgg aaaagactca accttgacct cctaatacaa tggagtatct
     5041 ggttgagttt cttttacaag aaagcagcca aggaaatcaa tcacgaaggt ggccggaaat
     5101 gatcagaatc ggattaacat cgtttaaaga acatgacaaa ttaactggta aaaagaataa
     5161 cactctttat gaatatgcag ggtttctacc cttagtggaa ttagatactg cctattatgg
     5221 aattccccga aagtcctcag ttgagaattg gataagtgaa gtacctgaat catttcgctt
     5281 tgtagtcaaa gtctatcaag gaatcagcgg tcaaggagac tggaagcctt attatcagac
     5341 cgaagaagag atgattgcgc attttttaga tgttatgtcg ccaatggtag atgctggaaa
     5401 gatgttttgc tttttagtcc aattcccctc atcattcaaa tgtacgaaag aaaatgtcca
     5461 gtacttgcgc aaacttagaa agtggtttga gggttatcct gtttctatag aattgcggga
     5521 ttattcttgg tacagcgatg aatttcttga acgtacaaga aactttatgt ctagagccgc
     5581 tttttcttta gccatcatcg atgagccaca gttgctgaat acaacgattc cttttgatcc
     5641 atttgtcacc aatccgaact ttgctctttt tcgattccat ggtaggaatg cgcaaggatg
     5701 gcaagcaaat gataaagagt ggcgtaaaaa aagaacgtta tatcgttatt cagaaaaaga
     5761 actgcaagaa ctagcacatg aagtcaaagt agttgattct aagacaaaag aggtaggtgt
     5821 gatttttaat aataattctg gtggtgatgc ggctgaaaat gcattagcac tgcaaaaaat
     5881 attaaatatc aagccagatg gactcaatcc aacccaaatg gatctgtttt aagggcttat
     5941 tttattcaag aaaggggcga agtctatgat caaagctatt ttttttgata ttgacggaac
     6001 attggtcacc aatcgttcaa aagcgttgga atcaacaaaa caagcaattg aatatgctcg
     6061 gaaaaacggc attttatgcg gtgtagcaac ggggcgcagc ccagtaaaga tcaaagaaat
     6121 cattgatgaa ttggaattag atatgtatgt cgtgtataat ggtcaactgg tttttactgc
     6181 agatcgcacg attatcgacc acccttttga acaaaaagta ttggaacata ttgttgaatt
     6241 tgcagatgag aaccatcgac aaatcgtttt tggtgcgaga aatcggttag atggatcaac
     6301 gacgatgcta ttaggacaat cgatttttat caagcgacta gtcagctttt taccgcgtaa
     6361 attcccggta cgtctgatga aaaaaatcct ccaggttttt agccctcacc gacaaaagga
     6421 tcgttatgaa acgttagaga tattaaaaga accaatttat caatgtatat tgctcagtcc
     6481 ggagtcagaa cagaaaaagt tagaacatcg ctttcccgag tgtacgtttc agcgttcaaa
     6541 tacgtatact gtagatatca tcccaaaagg tggttcaaaa ttactaggca tccaagcttt
     6601 cgcaaatgct gtcgaaattg aaatggaaga aattatggca ttcggcgatc attacaatga
     6661 tatcgagatg ctgaaaggtg taggaattgg agtggccatg gggaatgctc agatcgaagt
     6721 aaaacatgct gcagactttg tgactcaatc aaatgaagaa gatgggatat acgaaggact
     6781 gaaacacttc ggtctgattt attagtcaat gaaagaagga aaaaatcagt atggaagcag
     6841 agacaccttt tcaaaaagta gaaacattcc acaaaacttt tgatccaaga agaccagaga
     6901 tacccacggc ttttacagaa aatgaagctc atacacgtgc tgcgttcaaa atagaagaac
     6961 ttgttgaatt tgttgcagct acttcaccta ataaagaaca actgcatgaa gctgttatgc
     7021 tgctgcacga agcattagat aaagcagaag aaaaaatact tggtaaaaca cagtggggaa
     7081 gtgatccgct ggttgaacaa gtagatgcac tgacagatat cctttacttt acttatggtt
     7141 ctttttcatt actaggaata gtgcctgatc gaatattcga aatcgtccat caggcaaata
     7201 tggggaaatt atttccagat ggaaaacctc attatgaccc tgtaacaaat aaagtgttga
     7261 aacctgaaaa ctggcagatg gaatatgctc cagaacctaa aatcgcggca gaaatccaac
     7321 gtcagattca agaagcgatt gctaagaaga aatccgctga tataggcatg tgcacaaatg
     7381 aaaaagagtg atcagagttt cactattttt gttatcttta tacgatggaa aaacaaaaga
     7441 ttttcgttta agttagtgaa tgcatgaaaa tagtatgcta taatctagaa tagatgtctt
     7501 ttgcacgaga gacgtattat ttggatttat gccaagcaga acgccatctg ttgcataaaa
     7561 gatgcatact gaaaacggag gaaccataaa tgggaaataa tgttatcatc ggaatcgtca
     7621 ttgcaatcat tatagtcgcc attgtcgtct ttttggttag ttacttgatg aagaaaaaaa
     7681 accaagatcg attggatgcc ttagaaaaac gcaaggaaga attatttgac ttgccagtga
     7741 ttgaagaagt cgatgatgtt aaaaaaatgc atctggttgg gcaaagccaa aatacctttc
     7801 gtgaatggag tcaaaaatgg aatgacatat ctacttcctc gttcgctgaa ctagaaagtc
     7861 aaattttcga agtggaaaac ctcaatgaaa gttttcggtt cttaaaagga aaaaaagcag
     7921 ttgttgaagc agaagctaca atggaccaaa tggagaaaca agtgacggaa atccgtgaag
     7981 gtctaaagga attgcgggaa acggaagaac gcaactcact agctgttcag caggcacttg
     8041 acgtctatga agaactgaaa gaaaaagtca gagaagacga gcatgaatac ggaccagctc
     8101 tttttgaatt gcaaaaacag atcaaagtga tcgaaaaaga atttacgcag tttgtgactt
     8161 taaacacttc tggagaccct gttgaagccc gcgaggtttt ggataaagca gaaaaacata
     8221 cgtatgaagt ggaagctctg atgaaaaaaa ttccaccgct gtatgaggag ctccatacca
     8281 ctttccctga acaacttgaa gaaatcagtg atacttacga gaaattgatg gaagaacaat
     8341 atgtattccc agaagaagat cttgctgaag atatcgcaaa agtaagtcga agaattgaaa
     8401 attcattagc caatcttgaa aaaacagaag ttgaaacggt cgaatttgaa aaccgtgaaa
     8461 cagctgattt gattgattcg ttatatgata tcttagaacg ggaaatggaa gctcagagat
     8521 atgtaaaaac taaccaatca acgattgcag agtatatcaa acatacaaca aagaataacc
     8581 gtcaattatt gattgagctg gatcacacat ctcaaagcta tacattgaac cacaatgaaa
     8641 ttggccgtgt acgaggtttc caaaccgaag tggaagaaat ggaacgtcaa aatgaacaga
     8701 tgattccaca gatccgtcaa cacgaaattc cttattcaga agtgcgcacg ttctataaaa
     8761 cagtcttcaa agtcttagaa gatatcgaaa agcaacaagt agagatcgac gactcattac
     8821 atgaattgag aaaaggcgaa aaagaagcgc aagaaaagat cgatacattc gaattcaaat
     8881 tgcgcagttt gaaacgtttt gtagaaaaac aacgtttgcc tggcttgccg aatgattacc
     8941 tagaattctt ttttgttgct actgaccgta ttgaagaact aagtgttgtc ttgaataaaa
     9001 ttcgagtaaa catggaagag gtcaatcgtt tagttgctct atgtgaagaa gatctagaat
     9061 tattagataa gaagacacat gatttagtag atgcagcagc attaacggag caaatgctcc
     9121 aatatgcaaa tcgttatcgt catacacacg aagaagtgag agaagcaatt gataaaagct
     9181 actatttatt caataaagaa tatcactatc aagaagcatt agacgaaatc ggtacagcat
     9241 tagagcgagt agaacctggt gctttcaaac gcatcgaaga tttttatttt aatcatccag
     9301 acttagtata aagcaaaaaa gttagtaaac cagcaagagc aagacggatt attgtcttgt
     9361 tcttgtcttt ttttgtatat ttgaaaattg aaacaagtga aaatttcacc tgctcttgaa
     9421 agcaccttgg acaaccgtta taatagaaaa gaatttcaaa aaagaggggt ttcttatgat
     9481 atattttgat aacagtgcaa caaccccaat ctttccgcaa agcttagatg catatgtaaa
     9541 aaccagtcag cggattattg ggaatccatc aagcttgcat gatttaggca atcaagctaa
     9601 ccggttgttg cagcaagcaa gaaagcagat cgctgatttg atccatgtag aaccagaaga
     9661 aatctatttt acttcaggcg gaacagaagg agataactgg gtattaaaag gaacgatgat
     9721 cgaaaaaaga gaatatggga atcatatgat catttcagga gtcgaacatc cggccgtcag
     9781 cgagacagca gaacaattaa aagaattagg aatcgaagta agtatcgccc cagtggataa
     9841 acgcggattt gtacgtgtcg acgaattgaa agaattaata agaaaagaga cagtattagt
     9901 ctctgttatg gctgtgaata atgaagtagg atcgattcag cccatccagg aaatcagtga
     9961 tcttttggat gattttccta aaattcattt ccatgtagat gctgttcagg cgattggaaa
    10021 agtaccattc tcgcaatggt tgacagaaag agttgatttt gcaacatttt cagctcataa
    10081 attccatggc ccacggggaa ctggtttcat ttattggaaa aagggtcgtc gtttagcacc
    10141 attactgaca ggtggagggc aagaaagaaa tcagcgaagt gggacagaaa atgttccagg
    10201 tattgtggct atggttaaag ctttacgttt atcattagag ataaaggaac aaaaacctga
    10261 gcagacacaa cgcttaaaag tagctctaat caatgcgttg aagacgtatg agaaagtgac
    10321 gattttttca gaaggaactg actatgcacc gcatatttta tgttttgctc taaaaggaat
    10381 tcgcggcgaa gttctcgtcc atgccttaga agaaaaacaa atatttgttt ctactactag
    10441 tgcctgctcc tcacgtaaac atatggcaag cagtacattg cacgcaatgc atgtaccaaa
    10501 tgatctggct acatctgctg ttcgaatcag cttagatgaa aacaattcgc ttgcagaagt
    10561 cgagcaattt atgattattt tcaagcagct ttataagaaa ttttctgcaa tcaattaaaa
    10621 gaggagtgtt cttgtgaaat acagtgaaat tatggtccgt tatggggaac tttcgacaaa
    10681 aggaaagaat cgaaaaagct ttatcatgca actagcacaa aatgtcagac aagctttgaa
    10741 agactttcca gaaatcaaaa tccatgctga tcgggaccgg atgcatcttt tattgaatgg
    10801 cgcagacggg cagctagtta ttccaaaact agcaaaaata tttgggatcc aaaatttctc
    10861 tccaagtatt cgtgtagaaa aagatgtcga agttttgaaa caagctgttc aagacatcat
    10921 gaaagaaatt tatactggga aagaaacatt taaaattatc gctaaaagaa gcgatcacca
    10981 atttgaattg acaagtaatg aattgaatca aacattaggt aatgctgttt ttgatatttt
    11041 cccgcatatc caagttcaaa tgcgtcaacc agatattcca ttacgtgtag agattcggcg
    11101 tgatggcgct tatctatcgt atgaaacgat caagggagct ggaggattgc ccgtaggaac
    11161 aagcggaaaa ggaatgctta tgctttctgg ggggattgat tctcctgtag cagggtactt
    11221 tgccatgaag cggggagtgg aaattgaagc tgttcatttt gctagtccgc cgtatacaag
    11281 tgaacaagca ctgcaaaaag caaaagatct aacagccaaa ctagcacctt atgtgggaac
    11341 gatccatttt atcgaagtgc catttaccga gattcaagaa gaaatcaaaa agtcagtgcc
    11401 acaaggatat tggatgacaa ttactcgtcg aatgatgttg cgtttgaccg atgaaattcg
    11461 ccgtattcgt catggtttag tcattttgaa tggtgaatca ttaggtcaag tggcttcaca
    11521 aactttgcaa agtatggtgg ctatcaatga agtaacgaat acgccaatca ttcggcctgt
    11581 agcgacaatg gataaacttg aaatcattga agtagcagaa cagatcgata catttaatct
    11641 ttctatccag ccttttgaag attgctgtac gatttttgct cctccacagc caaaaacacg
    11701 ccctcaactg gaaaaggtcc atcaatatga agagcgttta gcaatagatg aaatgatcca
    11761 acgagcacta gctggcttga agatggaaga gatacaagca gaatcgtcta atgaaaaaac
    11821 tgaagaattt tcagaattgc tataagaggt tatgaaaata gtgttttgac cagagtatta
    11881 gagaaacaaa acgaaaaaat agctccatgt attttaccgt ttttgaacta atgtcgaaga
    11941 ttagctgatt gaataccatt tatcaagaag ttatggaaaa gccggttctt ttttactaac
    12001 tgaaaaataa aattttattt agagatcaag ctacagttga taaatgatat aaaaaagaga
    12061 atttcccatg aaatagcgag gttgtgacag aagtgggcag cttcaagaaa taagaaggaa
    12121 tttacgaaaa ttgcttttca aatttttgtg aaatttcggc ttatttttcg aagaagttac
    12181 ttctggaaca ccgtgtatca gaggttg
//
LOCUS       DAFLWC010000088        11837 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.090, whole genome shotgun sequence.
ACCESSION   DAFLWC010000088 DAFLWC010000000
VERSION     DAFLWC010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11837
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.090"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            5..2377
                     /locus_tag="L1V17_002353"
     CDS             5..2377
                     /locus_tag="L1V17_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237091.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQKMTNGQ
                     PMNDKRNGRSWFNQQERIENKVQSLREEIKQQEEYVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESAFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     RPTDSMKEKENDHFYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTLETPENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2438..3898
                     /locus_tag="L1V17_002354"
     CDS             2438..3898
                     /locus_tag="L1V17_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HBN1237092.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQIKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            3909..6113
                     /gene="topB"
                     /locus_tag="L1V17_002355"
     CDS             3909..6113
                     /gene="topB"
                     /locus_tag="L1V17_002355"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBN1237093.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLRAEEISTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTEATYES
                     LTPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGVLLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSIDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            6129..6278
                     /locus_tag="L1V17_002356"
     CDS             6129..6278
                     /locus_tag="L1V17_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237094.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKLRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6353..6946
                     /locus_tag="L1V17_002357"
     CDS             6353..6946
                     /locus_tag="L1V17_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HBN1237095.1"
                     /translation="MQEKLKELLAIRDGNLSMKEARKLGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEIEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            6959..7858
                     /locus_tag="L1V17_002358"
     CDS             6959..7858
                     /locus_tag="L1V17_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HBN1237096.1"
                     /translation="MTPTQFAAKTRNLAKRTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTAQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIIGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            7861..8358
                     /gene="ssb"
                     /locus_tag="L1V17_002359"
     CDS             7861..8358
                     /gene="ssb"
                     /locus_tag="L1V17_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBN1237097.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMVTLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTTFEQRDTATPNNNGLNALQNPFGNPFGGQSIDISD
                     DDLPF"
     gene            8724..8984
                     /locus_tag="L1V17_002360"
     CDS             8724..8984
                     /locus_tag="L1V17_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237098.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            9429..9635
                     /locus_tag="L1V17_002361"
     CDS             9429..9635
                     /locus_tag="L1V17_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HBN1237099.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGQRAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            9683..9886
                     /locus_tag="L1V17_002362"
     CDS             9683..9886
                     /locus_tag="L1V17_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237100.1"
                     /translation="MVDKEVISEKVAEALLIPRYWTIETPLVEDAPTMLFEDLVKIAG
                     YELHYQENMETYENEYWLTKLEN"
     gene            9902..10339
                     /locus_tag="L1V17_002363"
     CDS             9902..10339
                     /locus_tag="L1V17_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237101.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            10332..11039
                     /locus_tag="L1V17_002364"
     CDS             10332..11039
                     /locus_tag="L1V17_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237102.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKHRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSCTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATIDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKRQ"
     gene            11419..11598
                     /locus_tag="L1V17_002365"
     CDS             11419..11598
                     /locus_tag="L1V17_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237103.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
BASE COUNT         4428 a         1966 c         2463 g         2980 t
ORIGIN      
        1 gaacatggca gaagaaaaag aaccactaga caatagtcgt ttgggaaaat ccaaaagaaa
       61 actagtacga ttgcaaaatg aattaaacga acaaattgaa aagatgtttg aacaccaaaa
      121 aatgacgaac ggtcaaccaa tgaacgacaa gaggaatggc cgttcatggt ttaaccagca
      181 agaacgaatc gaaaataaag tccaaagtct gagagaagag atcaagcaac aagaagaata
      241 cgtggaaaag cttgaaagac aagaagagct aaaggaaatg ggctataaca agtacggcgg
      301 actggatatg acgatcgata atattccaag aatcaaagaa gaaatcgaac gctttgaaaa
      361 aggtgaatcg gctttttcag ccgccacgat ccgaaaatac caacggaagt tggaaacatt
      421 agaacagctg aaagaaaaat cagaaaaagg aaaagaaaat atcctccctg aagtacaagc
      481 gatcattgac agcggacgag tgacgcaatg gaaaaaaaat ccaaccattt attttttgaa
      541 aggctatcga aaagttgctt tagaactgaa tgaaaacggg ggatttgagg aatcaaaaaa
      601 ataccaagcc acgtcggaag aggaaaaagc agctgttcgt gaattacttg aagaggctag
      661 accaactgat tctatgaagg agaaagaaaa cgatcatttc tatcgagtag aattcaacga
      721 aaatgatcca gaaaaaggat tgaaaagtta tggtggggag atcgtaacat tcgaattgat
      781 cgatcaactc aaaacattgg ataaccaata cgccgcagaa gcaggttatt ataaattcta
      841 ttttgaggaa gtgaagaacg gagaagtagt cgatcagatc cgaatggatc taggggatgg
      901 cgtcaacagt aatcaaccaa tctatttaga gttagcaaaa ttgtgcgaac aagtacctga
      961 gaaggaacaa aaacaatcgg tcaaaaatga acctgtttcg aaagaacaaa tgcagtcgaa
     1021 agaaacaaaa acaaaacaaa agggctatca aaaacgaacg gcagaagaga ttaaacaaga
     1081 agttaaatcc ctttcgcaac aggcactgga tgcggtgaaa aagcataccc attctcctga
     1141 agacgtcaaa gaacttttga actttatgtc tcgttttcca gaacgatcct ttagaaatca
     1201 attattgatt gaggaacaat ttccaggtgc aacggcttgt ttaggtcgtg ccgcgttgaa
     1261 aaaagaagga atctatatca aaaaagggga acaagggaac aagatctttg tcagaaaaac
     1321 ggtcaaaggg ttttatgaga aaggacgtgg ctttgttcga gaaacagaag ctacaccaga
     1381 agataaaaaa cgaatcgaaa gtggtcaaat cgaagtgatc aaaaaacctt actatacgat
     1441 tgaaaaagtg tttgatatca cacaaacaca gttaaaacct gaagactatc cgaaaatctt
     1501 tccgaaccgt gtctttgatt ttcaattgga taaaaaagga cagtcagaac ttcaagctgg
     1561 gattcaagcg gtagccaaca atattggaat acaaattcga gatatgacag aaagtgaagt
     1621 ctatcaaaga gaattaggac aagcacgtgg ggcgtatgtt cgtaacgaat ttactggcga
     1681 agaagaaatc gtcatgaata ctcgaaatac tcctacgcag catttagcta caagtattca
     1741 tgaattagcc catgcaagaa tgcacaaatt ttcagaatta gataccgcaa ctaaagaatt
     1801 gcaggcagaa atgacttctt atattgtgtg caaacatttt ggaatggaca cgtcggagaa
     1861 agctattcct tatattgcag catggacgaa gaatggtcag acgttggatg ataaggaagc
     1921 tgcggaacgt gggaaaatca tgaatgatgt cagccgtgtc gcaaatgaat tcattcaaac
     1981 catttctaat gaaatcaatc aatacagaga aagagaacca gagatccaac cagcagaagt
     2041 gaagcaggag cataaaaata ctttagaaac gccagagaat aagaatattg tgcccgttgg
     2101 ttcactttgg atcgacaaga aagacgggaa agtaatggaa gaagatacgg gtcgaacgtt
     2161 acatttgaag gatgcggcgt ttattgaaga tccgcagcat aatcaagtaa ttttaaaagg
     2221 aaaaagttat ggaaaagaga tccaaacggc gttaccttca gaagaatttg cgctaggaaa
     2281 tccattccga ttttcacttg agacagtgtc agaagtggca aaacgaaaaa atgaaatcta
     2341 ttatgaacaa caattgtcac aaaaagaacg tgtataaaac aagtaaaaaa gactatctga
     2401 aaaacggata gtcttttttc ttttgggagg ttttaaaatg accgagaaaa aaatgagtct
     2461 tattgatcga tgtaaacaga tcgatatagt ggattttgct cgaaacaatg gaatggctgt
     2521 agtcaataaa ggacgagatt atcgcttaga agaccatgat tcatttgttt ttgatcgaag
     2581 aaaacaacgt ttttattgga acagtcaaaa tattagtggc gacattattg aattagctaa
     2641 actttttttc atagacaaag agatccaaga ccctaagcaa caatttaaag cagccactga
     2701 ttttattcta aagaatgaag acaaaacaga acgagtggaa aatcttcatt ttgaaacaga
     2761 aaagtacaaa gatcaccccg ttgattatca accactcaca gaaaaaggaa ggaattatct
     2821 gaaggaagaa cgaaaactac cagagtggct gattgattat gcagaaaaag aagggttgat
     2881 tgccgaacta aagccaaaat atgaacggca aaatttctta gttcgagacg atcgtttaga
     2941 tcatgcggtc gcctttttat ggaaagatcc acagacaaaa gagacagtag gggcgagtta
     3001 tcaaggaacg ttcattgatt atgaacgttt tggtgagaga ggcacatata agcatataga
     3061 taaaaattcg acagcgaatc atggctttaa cctaaagatc ggtgacccta agcagataaa
     3121 attttttgag agtagtattg atttacttag ctatgctgca ctgaatcgtg atcagttaaa
     3181 cgatacgtgg ttagtctcta tggaagggtt aaaacaccat gtgatcagtc attattttgg
     3241 tgaggcagta tctgaattga gaaagaaaca agcctttcct caatccatcg agatttgtgt
     3301 ggataatgac cgtgcaggac atattttcta cgaaaaagaa caattaatgg gcgcagtcga
     3361 tccatttacg aatcagaaag tacgttgtga acgaggaatc gctaatgatt ggcaagtgcc
     3421 aaaagaatac aaaatcattt atgaagaagt cgcaaaagaa gaaaaggtca caccagaagc
     3481 tattatggcc atacacaaga cagaaaacaa tctgcaatta acgaaccaac tggtttccgc
     3541 tcacaaagta aatgcgtttt ttggccagca gctttctgtt aacgattcaa tagaagccat
     3601 taatttgaaa gatatttgta gagaagtcgc aaaagaatta aaagtttgtg aacgcgtgga
     3661 tggtacgtac gattttgatc gtttttatca agaaaaaggg gatattaatg cgcagattct
     3721 tttctcttat aaagcagaac aatactacaa aggctataaa aatcatgaac atgaatttgt
     3781 acctgaagta aaaaaggact ggaacgatca attgaagcat gagatccagc aacaagaaat
     3841 cagaaagcaa aaacgtgcca tgttgtttca acaaggcaga caacaagaaa gggagtgaaa
     3901 tcgtcatgat gaaaaccgtt attttagcag aaaagccgtc acaagcgaaa gcttatgccg
     3961 atagcttctc taaagccact cgaaaagacg ggtattttga aatccaagat cgattgtttc
     4021 ctggtgaaac tgtgatcacg tatggttttg gtcatttagt cgaattagat tcgcccgata
     4081 tgtacgatga aaattggaaa caatggtcat tagaacattt gcctattttc cctacacatt
     4141 atcactatca tgttcctaaa gataagaaaa agcaattcaa ggtggtgaaa cagcaacttc
     4201 aatcggccga caccattatt attgcgacag atagcgatcg tgaaggggaa ctgatcgctt
     4261 ggacgatcat tcaacaagta ggcgccgatc aaggaaaaac ctttaaaaga ctttggatca
     4321 actccttaga aaaagaagcc atttatcagg gattccagca gttacgagac gcaaaagaga
     4381 cctatccaaa atttgaagaa gcacaagcac gtcagatcgc cgattggtta attgggatga
     4441 acggtagccc actgtatagt ttactcttgc agcaaaaagg cataccagga agcttttcct
     4501 taggcagagt ccaaacccca acgctttaca tgatttatca attgcaggaa aagattagaa
     4561 atttcaagaa agaaccttat tttgaaggaa aatccgaagt aatcgctcaa aatggcgcat
     4621 ttgatgcgaa gcttgatccg aatgaaaccc aagcgacgca agaagcattt gaagattatt
     4681 taaaagaaaa gggggttcaa ttgggaaaac agccaggcat gattcgccaa gttgaaaccg
     4741 agaaaaaaag cgcggcaagt ccacgtcttt tttctctatc cagccttcag tctaaaatga
     4801 atcagctcat gaaagctagt gccaaagaca ctttggaagc catgcaaggc ttgtatgaag
     4861 ggaaatatct aagctatccg cgaacggata ccccttacat tacggaaggg gaatatgcgt
     4921 atctgttgga tcacttagac gaatacaagc attttttgag ggctgaagaa atttcgactc
     4981 ctattcatac accgaatagt aggtacgtga acaacaagaa agtccaggaa cattacgcaa
     5041 tcattcctac aaaaacagtt atgacagaag cgacgtatga aagtctgaca cctttacaac
     5101 aagcgattta cgagcaagtt ttaaaaacga cagtggcgat gtttgcggaa aaatatacct
     5161 atgaagaaac aacgatcttg acgcaagtcc agcagcttca gttaaaggca atcggaaaag
     5221 taccgataga tctaggttgg aagaagttat ttggcaaaga gagcgacgga aaagagaagg
     5281 aagaagagcc gctacttcct aaagtgacaa aaggagaaat ggtgacggta gatctacaag
     5341 tccttgaaaa agaaaccaag ccaccacaac cttataccga aggtacgttg atcactgcga
     5401 tgaaaacagc tgggaaaacc gtggatagtg aagaagcgca atccatattg aaagaagtgg
     5461 aaggaatcgg tacagaagcg acacgggcga atattattga aaccttgaaa caaaaggaat
     5521 atatcaaggt agagaaaaat aagcttgtgg tgacgaataa aggggttttg ctttgccaag
     5581 ctgtggaaaa agagccgctg cttacgagtg ccgaaatgac cgccaaatgg gaaagctact
     5641 tgttaaagat tggagaacga aaaggaacac aaaccacttt tctagccaat atccaaaagt
     5701 ttgtctctca cttattggaa gtcgtcccag gacaaatcca atccattgat tttggatcga
     5761 cgttacaaga agtgaaagca gccagtgaaa agcaagaagc cgcgcgtcat ttaggaattt
     5821 gtccaaaatg ccaggaacaa gaagtcttac tctatcaaaa ggtggcagct tgtacgtctg
     5881 aagcctgtga ttttaaatta tggacaacga ttgccaaaaa gaaactcaca gcgacacagc
     5941 tgaaggagat tattcaaaat agccgaacaa gccaaccagt gaaagggtta aaaggtcaga
     6001 agggttcgtt tgaagcaacg attgttttaa aagaagactt cactacaggc tttgaatttt
     6061 ctgaaaagaa aaaaacgaac ttcaagaaaa gaacacgacg cacgacaaaa taatggaggg
     6121 ttaatcttat gcgtaataca acacacaaac aacaagaaat cgaaaatcaa aaagccaaaa
     6181 ttcgttcaga acaagagaaa ttacgtgcca gtaaaagaag acttcagcaa ttaaagaacc
     6241 agcaacggat tcaaaaagaa atcgaattag atcgatagac attaaccttg ttacaaatac
     6301 actatcatga tatatttaat gtagtgtatt tgtaacaaaa ggggggaagt aaatgcaaga
     6361 gaaactgaaa gaattgttgg ctattcgcga tggaaattta tctatgaagg aagccagaaa
     6421 attaggaatc gcagcaacca ctgtacaaag attggtgaat caaggaaaat tgatcaaagt
     6481 tgatcgtggt tattatgtag aggatggtca tggaatagat gatttatttt ggcttcagca
     6541 acgtttttcc aggggaatct tctctcatga aacgacttta gatatttacc agctttctac
     6601 gaatatgccg aaattcattc acttaacttt tccccatgga tataacgttg atcgttcaat
     6661 tacaaaagag cagcagttac aatttcattt cgtgaagaaa gaagtttatg aactaggaaa
     6721 agtagaggga acttcctttc aaggaaatcc tattactatg tatgataaag agcgtacact
     6781 ttgtgatatt tggaatccga gatatgaaat tgaatatgaa atgaaattag aagcattaaa
     6841 agagtacatg gaagacccat tgagagatcc aagtaaatta agagattaca tgacaaaact
     6901 acatgtagaa aaagaaatga aataccacat gcaaagctta tattgatgga ggaaaaagat
     6961 gacaccgaca caatttgcag caaaaacaag aaatttagca aagaggacag gattaaatgc
     7021 acagttagta caacggcatt ttatgatgga tcgtttaatt gaacaaattt ctgaatctaa
     7081 gtataaaaat gatttcattt tgaaaggtgg ctttttatta ggatcaaaat atggaatcga
     7141 tagaaggacg acaattgata tcgacacgac atttagaaat agcaaattaa ctgaagaaaa
     7201 attgaagagt atttttaatg atttaactag gaaacccacg aaagaaggta ttgttttctc
     7261 tattcaagga atgaaggaaa caagagaagc cgatttttat cctggatttc aaattaaatt
     7321 ggtggctaat ttagagaaag tacgtgtgcc atttaaaatg gacgtgacaa caggagattc
     7381 tatttatcct gaagtagata cacactatca ccaattaatg tttgaagata aaaaggtgga
     7441 gattccagct tatccaacag cacaaattat tgcagaaaag ctaagtgcta cgttcagctt
     7501 tggcacagat aattcgagag caaaagatta ctacgactta tttaccattc cgaaactaga
     7561 aaatatcgat acgaaagagt tatacaaaag tgttcgaaat acatttacaa aacgtgggga
     7621 tacaaaaccg ttgtcctttt attatgaaag agaaatggat aagatcatag gaaatgacta
     7681 tttggaaaag cagtgggaaa aatatcgctc agttaacacg tttgcgaatt ccatttcatt
     7741 tacagataca gtcaacgaaa ttgatcacct aatgaaaagt gtgatcaaaa ttgaaaatca
     7801 agaaagaaaa cggcagttta aaagatcaca acaaatgaat caagaaatgg agagataaag
     7861 atgatcaata atgtaacttt agtaggacgc ttaaccaaag atccagattt acgttatacc
     7921 gcgagtggta ctgcagtagc gacttttacc ctagctgtca accgaaattt cacgaatcaa
     7981 aacggcaatc gagaagctga ttttattaac tgtgtgattt ggcgcaaacc agcagaaaca
     8041 atggtgacat tagctaaaaa aggtagcttg attggtgtag ttgggcggat tcaaacgcgg
     8101 acttatgaca accagcaagg acaacgtgtg tatgtgacag aagttgtggc cgataatttc
     8161 caactattag aaagcaaagc agcgacagaa agccgtgcgc acgctgatca atcgtccacc
     8221 agtccaagca ccaccacttt tgaacaacgg gatacagcga cgcctaataa caatggattg
     8281 aacgctttac agaatccatt tgggaatcca tttggtggac aatcaatcga tattagcgat
     8341 gatgatctac cgttctaagt agcattttct attggttgca tttgctacgg tttatgttat
     8401 aatttagtca acaaaaagaa ttttcaatct ataaccaaaa accactagct ggcgggctag
     8461 tggttttctt ttacgtttct attataagaa ttaacgggta ggcttactgt ctttcttggc
     8521 aaatttacaa tcaagccatt tgcagatata gtgcgcggct acttctgcca tgattgcaaa
     8581 aacaaaatca aaaagaattt tcaaacctat aacctcctcc ccttgccaga ttaggccggg
     8641 gtagcagaca gcaagactat tatagcataa ttgaaatatc caaatgattg gatttttgct
     8701 ataattttag cgaggtgatt gtgatgaaca aatatgttgg tttgcttgat aaaatccgag
     8761 taataaaaac gcaaccgtta ttggttcgct ttactttaca aacgattcat gaatcgatta
     8821 attgtgtagt tgcagatatt gaaattatcg ataaattgct aattatggat gatggaaaat
     8881 acaatattgc cgtcacaggt cacttcaata aacgaaatca gctagttatt gctagcatgt
     8941 atgttagaaa tcccgatcat tttacgcgat cgatgggcat ataaaaaaag aagagttgca
     9001 atcctaatgt aggactgcag ctctttttgt tttacataga aacaagaaaa atgaaaaggc
     9061 ctttttagga aggcgcgagc gccttctcaa ttgaaaaacc tctctcactc caaccgccac
     9121 cgccgttcga gaagaaagga agtgaacgtt gcacgttcac taagataaag ggtcttgcaa
     9181 agcaagacaa aatagaaaaa acttcctctc accaaaaggt tcgttcctgt tcgttatctc
     9241 tttattgatt tgccagaccg gcaacaagtt gccttttatc accaaaaagc gacaaggaca
     9301 agggtaaatg gcacgctgcg cgcccttgtc cttgtcgctt ttcgttgatt cattctggcc
     9361 aacaaatcaa taaagaaaga actaacgaaa ggaagtaaaa cctttcctaa gaggaggcag
     9421 aatcaatcat gcgaaagaaa tttgattatt ggggtgttcc cttcagcgaa ttattcccaa
     9481 actatcatgc accacatact gtcgaatgcg attgtggaca aagagcgaaa tgtatcaaaa
     9541 gctatcgttt gtatcaatgt ccaacatgcg gaaaaaaata caccttgtct tatggcgatt
     9601 atattttgat tgatgagaaa ggaaagaaac gctgatgaaa acataacata aattattgac
     9661 tgtaaaagaa gtcgttcaaa ttttggtgga caaagaagtc atttctgaaa aagtagcaga
     9721 agctttactt attccgcggt actggacgat agaaacccct ttagtagagg atgcaccgac
     9781 tatgctattt gaagacctag tgaagattgc aggatatgaa ctgcattatc aagaaaacat
     9841 ggaaacttat gaaaacgaat attggttaac caaattagag aactaaaaag gagaaaaaaa
     9901 tatggctcaa aattactatg acgaatttgt caaattacct ttggataaaa tggcacaaaa
     9961 aatggaggat atgacattcc tataccatga gacacgtgtt ccaaaaaaac attataagga
    10021 aagattgtcg gtagctgtgg aagaaatgat tgaatcaggt gtcgaaatga atctcattgc
    10081 gacgtactat cgaacactgg aagaactgaa aaaacaaaat gcaaaatggt ttttccaagc
    10141 cttactatgc ttggaagtag gtgtcaaacc aagcactatt aaaccttctg aatatcaagc
    10201 tttagaacta acgtatggga aatttgtcga aacgaaaaaa gccaagactg tttcaagtga
    10261 atggttagat tattttgaaa atatcaataa gtatggcgcc tattacacca tgaaaaagga
    10321 ggacaacgaa aatgaataag gtgatttatc aactaacaac ggaagatgtg tcacactttt
    10381 taacaaacaa agaacatttg aatgaagtaa tcagacggat tcaaaaagac tttagttgta
    10441 tggaagaaat gaagtacttt attcaaagag tcgaagaaca attgtatttg gaaagtgaaa
    10501 cgagtcaaac gaaggtcaca gtcagcaata attatttaga cgtgtataaa catcgtcctg
    10561 aaacggtaaa aaaaggaacg gagcttctac gactagaaac agaaaaatac atcatgaatg
    10621 tttacctaga aaggagtgaa ctggtcgaaa actttgtcag ctgcacgatt tgcaggaaac
    10681 actattactc agaatcagaa tattattcaa tttttgagag catggaatta atggaagaag
    10741 aaatggaaga gctaaacagc aaaaatgcga cgatagacga ttattatctt gtatttacta
    10801 gatttttgac gtgtggaacg gaatctatcg tgttaatggg aatggattat gaactcgctg
    10861 tacccgaagc atttttgagg gaatatgtag aagaagtaga taacccaggc gacgactggt
    10921 acacgacttt aactgatttt ttagatacct acacttacga cgatacagaa gaaatccaaa
    10981 atgaacttga ccgtaaacga atgccatatc aacgatttga aaggaaaaaa aggcaataat
    11041 catttatacc gaaaagtgag aatgtgtgaa ataagaacaa aaaccttgaa attaagggaa
    11101 tggttcttat ttcgcaccaa tcgctccaac cgcccccgcc gcttaggtgg tgcgaaataa
    11161 gcgggcaaag cccgataacc taagagaaag aaggagatcc atatgaataa aatcattcct
    11221 ctgttgttcg tactgtgtat tggcgagata cttatgcgtc atggtgcagc tgtacattta
    11281 aacttcgtag tattcttagg aatactagta ttttgtttga ttttttggcg ctttgtgtta
    11341 gcccttgtga gtctactatt caagttgatt gcagccatat ttttcatagg gttatttcga
    11401 tgaaaggaga gagtactaat gccaattgca ataggaaata aacggttacc cgtgacatta
    11461 gatgaaaaga gacaaaaaga attgcagcaa ctaaagcaga agtacggaaa aagtgaatct
    11521 aagattatgt gtattgcgtt agatctattg atcgcgcaag aaaaagcagg atttgatata
    11581 ccagcactaa aaaagtgacg tcacttttca tttgaagaaa caaaagtgat agcacttaat
    11641 tgttcctact atttagaata ttttctatgt cctttttatt ccattttgta tcaataacta
    11701 tgaaatcttt aaagtatcca gatcaatttt tttcttacct gattctaaag attttgtttt
    11761 cttaaacata ttatgatttc ctttcgacta ttttcatata aatgttaaca tagtttatgg
    11821 attcatggaa tgttaat
//
LOCUS       DAFLWC010000089        11617 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.091, whole genome shotgun sequence.
ACCESSION   DAFLWC010000089 DAFLWC010000000
VERSION     DAFLWC010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11617
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.091"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(85..264)
                     /gene="rpmF"
                     /locus_tag="L1V17_002366"
     CDS             complement(85..264)
                     /gene="rpmF"
                     /locus_tag="L1V17_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBN1237104.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(322..891)
                     /locus_tag="L1V17_002367"
     CDS             complement(322..891)
                     /locus_tag="L1V17_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBN1237105.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1077..1979
                     /locus_tag="L1V17_002368"
     CDS             1077..1979
                     /locus_tag="L1V17_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1237106.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="L1V17_002369"
     CDS             complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="L1V17_002369"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBN1237107.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="L1V17_002370"
     CDS             complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="L1V17_002370"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBN1237108.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="L1V17_002371"
     CDS             complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="L1V17_002371"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBN1237109.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8547..8732
                     /locus_tag="L1V17_002372"
     CDS             8547..8732
                     /locus_tag="L1V17_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HBN1237110.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8794..9990)
                     /locus_tag="L1V17_002373"
     CDS             complement(8794..9990)
                     /locus_tag="L1V17_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBN1237111.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10160..11596)
                     /locus_tag="L1V17_002374"
     CDS             complement(10160..11596)
                     /locus_tag="L1V17_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBN1237112.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
BASE COUNT         3423 a         2482 c         2041 g         3671 t
ORIGIN      
        1 attttttatt taccgactac aaaaaaataa acctcaaggc tccatggtta gccttgaggt
       61 tttacatttt ctaattaaaa tgtattaagc ttcttttgac attacgtcct taccatcata
      121 gtaaccacaa tttgcacata cgtgatggct ttttttcatt tcaccacagt ttggacattc
      181 gtttaaccct ttgattgtca atttgtagtg tgtacgacgt tttgcttttt tagcttttga
      241 tgttcttcta gctggtactg ccattttgct acacctcctt gtaaagtctt gtatctaaat
      301 tagacacaat atattccaat cttacttgtt atcgtcgtct tttgatttag aatcaaaaag
      361 ttcagatagt tttgcaagac gaggatcaat tttattctcg gcttcttcca tttttctgcg
      421 ctggtattct tcttcggaaa caacttccca atcattgcct tttggaagtt ctgttgctgc
      481 ttcctcttct tttgtcaata cccgcattgg aatcgccaat aagatgttgt cttcaatcga
      541 ctctgctaaa ttcaataatg gaccttcaat tagcaaaatc tcatctgcag acatttgttc
      601 atctctactt tggaattgtt cttctgtcat gaatacttcg tctacagaaa aatccatggg
      661 cagttcaaca ggttctagtg aacgtgttga aggaactgtc aaagtcgtct gcacagtgta
      721 atgaacgata tagcctttct tatcaactga gaccaaacct tcgacttcca ctggcgcaac
      781 atcaagtatt aaattgtctc gcttcatgag agcggctttc aagtcgagcg tctcatgaaa
      841 agttaacggt gtctcctggt attttctcaa ttccaataaa gaccatttca tttttcatca
      901 ctcctaagca acaaaagcaa ttatacaggg caaaaagcat gttgtcaatg aaattttctt
      961 gacaccttgc agttcataaa aaaacagaaa aatctttatt agaaagcctc tgtttgctat
     1021 catcctcaga atcatttaca ataatcatta ttccattaaa ggagcggatg atcttcatga
     1081 acacgaaaga tatcgaatac tatgtccaaa tcgtcaaaca aaaaaatttt acgaaagtgg
     1141 ctaattattt ccgtgtgagc caacctacta ttacatatgc attacaacgt cttgaaaaag
     1201 agtttgacac cgtacttatt acaagagatc gatcgcatca cgaattaatc gtcacgcctt
     1261 ctggaaagca gctgtttctc catgcacaaa ccattctcca agagatttct actgcaagag
     1321 ctgaaatcac tcagttgcaa aagaaaaagc ttcgttttgg catgcctcct attatcggca
     1381 atgaatactt tcctaaactg tcaagttact ttatcaagca tgaattgatg aatcaaattg
     1441 agattaccga tggaggctct cgggacttat acgggatgat ccgacaaggg aggatcgatt
     1501 tagctgtatt aggctcaaca cagccaatcg tggatcaata tttagaaaca gagttacttt
     1561 tggacaaacg tttcatgatc gtcgtgccac ctacacatcc tctttccaag caggatactg
     1621 tctctttcaa agatatagca gatgaacagt ttgtactatt gaacgaacat tatgtccacc
     1681 ccgcagcatt cactaagctt tctaaacaaa cacatactca tccaaaagtt gtttatcaaa
     1741 gcaatgactt gacgatttta aagagtatgg tccgagaaaa tgtgggtatc ggttttttgg
     1801 cagagattgc tgtccatcct gaagatcatt tagtttgcct ccctctttca gatgaagttc
     1861 agcctcgctt cttgatttca ttggcaaaac gaacacagca gatcgtcacg cctcttcaag
     1921 aacaagtagt ccaagttatc catgaattcg ttacagcaca aaaaaacagc tcttcgtaaa
     1981 agaagagctg tttttatttt ttattaagct aaattagata gctgttgttt cgccacggta
     2041 aacgatgccg cgacgtgaat caacggtaat caattcacct tctgtaattg ttgttgttgc
     2101 gcctttagca ccaacgatta caggaatatc ttgtgcaatt cctacaactg cagcgtgaga
     2161 agtcaatccg ccttcttcaa cgataacagc agctgctttt tcgattgcag gcatatattc
     2221 tttgtcagtt gatggtacaa ctagaaccat tccgtctttt gcttttttta cagcttcttc
     2281 agcagatgaa gcaataactg catttgcaac gacagatttt tgtccaacgc cttgagcttc
     2341 taataattta gaaccaatca tttgaatttt catcacgtta gttgttccgc gttcaccaac
     2401 tggtacacca gcagtgatca agattaaatc gccttctgat gcgaaaccta attcaacagc
     2461 ttttttagct gctagttcaa acatttcatc agttgttgat ggtttttcag caactgttgg
     2521 gtaaacgccc cagtttaaca tcaaaccacg ttttgtgcgt tcgtcaaaag taacagccaa
     2581 gatatctgca tctggacgat attttgaaat catttttgca gtgtatcctg attcagttgc
     2641 agcaacgatt gttttcacgc ctagattttt tgcagcacga gctacagata aaccgattgt
     2701 ttcagttaca tctgttttat cgaattcgtt caattggaat gtacctaatt ctgataatgc
     2761 attttcagct tcttggtcga tacgtgccat tgttgaaaca gcttcaactg ggtagtcccc
     2821 gtttgcagat tcaccagata gcattgttgc atctgtgcca tcaaatacag cgttagcaac
     2881 gtcagaagct tccgcacgtg ttggacgtgg gttttcttgc attgattcta acatttgtgt
     2941 agcagtgata actgggatac cagcagcatt acattttttg ataatgcgtt tttgaaccat
     3001 tggtactagt tcagctggga tttcaacacc catatctccg cgggcaatca taacaccgtc
     3061 agaaactttg atgatttcgt caatgttgtc gataccttct tgagattcga ttttagggaa
     3121 gatttgaaca tgagtcatgt ctttttcttc taagatttcg cggatatcta gaacgtcttg
     3181 tgctttacgt acaaaacttg cagcgataaa gtcgatatcg ttgtctaaac caaaacgaat
     3241 atcgtcagca tcttttggag taatacctgg caaactaata gaaacgcctg gtgcatttac
     3301 ccctttacgt gatcctagca tacctgcatt tttaacttct acgactaatt cacggtttgc
     3361 ttcgtctttt tcaatgattt gcatatcgat caaaccatca tcaaataaaa tgtgtccgcc
     3421 aacgtgaaca tcgtcaaata atcctgggta agtaaccgcg attttttctt ttgaacctac
     3481 atgttcagga tccatagaga tgcgtgtttg atctcctact tcaaatttga tgtatcctgc
     3541 acgaccaaaa tcagcttctg ttgtgccttg aacagttgta cggatttcag ctccttttgt
     3601 atctaaaaga ataccgacat cttttcctgt ctttttaact gcttcacgga ccatagtcat
     3661 acgtgataat tgttcttcat ggtcaccatg agaaaaatta aagcggaaga catttgcccc
     3721 agattcaatc aattgagaaa taatttctac tgagttactt gctggtccta atgtactaac
     3781 gattttggtt tttttcattt aaaaaactct cccattcaat tttgtttatt taaagctgta
     3841 cacagcttaa atagcttggt ttctttcact cttaaaatga aagtgaatta tttagatcat
     3901 atagtgataa gtctggttta tgtttgttgt tttcaagtgt atcaatgatg tcagacgcaa
     3961 cgatttcgtt gtcatggata ccgacacata atccaccttt tccttcttga agcaattcga
     4021 cagcgtaagc accgaattta cttgccaaca cgcggtcgcg tgcgcttggt gctccaccac
     4081 ggacaacgtg tcccaagata gatacacgtg tatgatagtc accaaattct gaaagtttct
     4141 cagcgaattc atttccgccc attacacctt cagccaagat gatcaagcaa tgtttcttcc
     4201 cgcgatcgcg gccttcttgg atttttttag caactgaagc catatcaaaa tcatgttctg
     4261 ggatgatgat ttcatccgct ccgccagcca cacctgacca taaagcgatg tctcctgcat
     4321 tgcgtcccat tacttcgata acgaatgtac gaacatgaga agtcgctgtg tcacgaatac
     4381 ggtcaattga ttctagtact gtattgattg ctgtatcaaa accgattgtg aaatcagtcc
     4441 caggaatatc attatcgatt gttccaggaa tacctactgc tgggaaaccg cgttttgtca
     4501 aagccattgc gccatgataa gagccgtctc ctccgataac cactagacct tcgattccga
     4561 attttttcaa ttgttcgatt ccttttaatt gaccttcttc agttgcaaat tctggataac
     4621 gtgcagaata caagaatgta ccaccacgtt ggatcttgtc acctacatct gccacatcaa
     4681 gacgacgaat atctccagca actaaaccgg caaaaccata attgatcccg tatacttcca
     4741 gtccttcgta aataccttta cgaacaacgg cacgaacagc tgcattcatt ccaggtgcgt
     4801 ctccgccact ggtcaaaatt ccgatgcgtt tcataataaa cattcacctc attaaaatac
     4861 tttatcctaa gtatgactta ggtttacaac catttttgcg ttaaccacga ctaacattct
     4921 aacattattt ttctcacttg tcttgattta cggataaaaa aatgaaaaaa aatgaaagca
     4981 agtagtattt tttaccgtaa gttatttgaa aaccacatta tcttcgccaa gcagataaat
     5041 aagttgcccc tttatactct tgctgtcatc cacccaataa gcatctgaca gaactacttt
     5101 tcgttgcgtt ttttcgtgat acataactac tggtatatat cctgggtgtt tctgaaaaat
     5161 cacttgtaat tgtttcatta tctcgggatc ttcccgttct tctgtaatac gcaaatagca
     5221 agtttgtgaa ggatactggg cttctaactg gttaggatca gcaaagcttt ctccaattag
     5281 ttgcagttcc tgattatatt tgctgatttc gctccgccct tgaacaaaga tcactcgatc
     5341 aacggcaaac aaattacgat atttacgata aagagttgga aaaactgtga cagaaatttc
     5401 tccactactg tcggttcctt caacaaaggc catcagttct cctttttttg tccgaatttc
     5461 tctaacttcc ttgatcatca ctaataaatt gactggttga ttagggacga tatctgtaat
     5521 cagctgaact tgtttagcta aacgaagacg atcaaaccct tctgcaggat gacctgacaa
     5581 ataaatacct aagtactcct cttccagctt caagcgttct tctagtgtat agtcagcgac
     5641 ttcttcttct tttaatgcca tgattcccag caagtcaaga cttccaccac tgtaaacgat
     5701 attttggatt tttccttcga gatcaagcat caattgtttc ctgttaggag ataattcatc
     5761 aaaaactcct actgctgtca gtgattgcag taactctaat ttcagccaac gcttatcgat
     5821 ccgtatgagg aattgatcca ctgactggaa cgggccattt tgttttcttt cgtttaatat
     5881 atcttctaca aaatcacgcc gaataccttt tatcgctgtc agtccgaatc tgatttcttc
     5941 cttattgacc aactcaaaac tggaattact ttgattaatg gacggcgagg aaagtttgag
     6001 tttattttta cgtgcttctg caatatattc tttcaatttt gatgtgttat gccgaacaga
     6061 attcatcagg ctggtaaaga aagcacctgg atgatgggct tttagatacg ccatttggaa
     6121 tcccacgaat gaataagcaa atgcatgtga ccgattgaat ccatagtttg caaatttttc
     6181 gatatattca tatacggtcg ctgctgtttt ttccgaatat ccctgttgta atgctcctga
     6241 tacaaaatgc gacttttctt catctaatac gtcttttttc tttttactca ctgcccgtcg
     6301 cagaatatct gactgcccta atgtaaatcc agccatagtc gaggcgatct gcatgatttg
     6361 ttcctgatag acgatcactc catatgtgtt tttcaaaatc gggatcagtg aatcatctgg
     6421 gtagcgaatg gcttcttttc ctttcttcct ggcaatgaag gtatctatat tttgcatagg
     6481 gcctggtcga tacaatgcat tgactgcggc aatatcttcg atgttttctg gatctaatct
     6541 tcgtaaaacg ttccggatac cagcagattc aaattgaaat actcctgagg tttcgcctcg
     6601 ttgaaacaag agcagcgttt ttgcatcatt tagcgggatc tcttttaatc ggatctcata
     6661 cccttctact cgcttaacag ctttcaaagt aaaatcaata atcgataagt tgcgtagtcc
     6721 taaaaagtcc attttcaaaa gaccgattgc ttctacctca ttcatcgtat actgggtcag
     6781 aaaagcttca tcagaaccgc gttggagcgg aactagttca agtagattct tatcgctgat
     6841 aactacacct gctgcgtgag tcgaaacatg tcttggcaat ccttctaaaa tcactgcagt
     6901 tttgaataaa agttggtttt tttcgcttgc ctgaactaat tctactaatt gatgcgaagt
     6961 tttataagct tgggtcaatg tgattttcaa ttgattgggt attgcttttg accagcggtt
     7021 tgcttcactt tgcgataaac caaacactct agctgcatct ctaagaacca tttttgctgc
     7081 cattgtgcca aatgttgcga tttgtgccat atgatattgt ccatactttt ctcgaacata
     7141 attcaatact tcttcacgtc gattgtcagg aatatccaaa tcgatatctg gcatcgtaaa
     7201 gcgttcgggg tttaaaaagc gttcgaacag caaatcatat tctaatggat ccacatctgt
     7261 gatttctaac acataggcta ctaatgaacc cgcagcagaa ccacgacctg caccggtaac
     7321 gattttgttt ctatgagcaa aagccattac atcccatacg atcaagaaat aatcatcgaa
     7381 tcccatttga tggatgacag ataactcgta gtccaaacgt tcttggtatt cctttgtata
     7441 gtcagtgatt cggcgttcca cttgcgaata gcataactct cttaaatatt ctccagcttg
     7501 ttttccatta ggaactggat aatgcggaag taatttctga tggaactgga attcaaatga
     7561 aatcgattca gctaaacgct gggcgcctat tacagcttgg gaaagacccg ctttttcgaa
     7621 tcgtttgatc atttcttgtt ctgaaagaag atagacattt gctgttagtg gtaaagatgc
     7681 agataaattt tctaaaggta tttggcttcc ctctttgata tgtttcatca cttcaagtgc
     7741 aaaaagttct tcttgttgta aactagcgat gggatgtaat gcacaaagcg aataattttc
     7801 ttttatcaca tactgatacc attcaggcaa ttgatcaggc gtgttttctg tcaagccgat
     7861 ataaaaattt ctagtaaaaa cattttcaag taaaaactgc caatgaccga aaaagttatc
     7921 ctctttattg aaagcctcag aaacagaatg atttgccgga acaacaaacg ctagatggtc
     7981 ggtttctgtc atttctgcaa gttccaattt ttcttggatc atttttcggc tggaaagttt
     8041 catcagctgc tgataaccta tttcatcttt tgcgtacgca agcaagccat aatttttttc
     8101 ttcataagta taactaagat gtaatccaat gattggctgt actccttctt ctacacaaat
     8161 acgatagaat tcaggtgcac cgtataagac atctttatcc gttatggcta atgaagtgta
     8221 gccttgtttt tttgcttctt gtacatattc tcgaatacgt atcgtacttt gtaaaagaga
     8281 ataagaagta attgtataaa gttgtgggaa aaacatcttg cattccgcct tttttttcgt
     8341 taaaattcac tagcgttaaa aggtttgatc cttttacttt cattaagata gcaggcgctg
     8401 aagttgatta ttccacttca tttgcttgct tgtaatctgt aggaatgagt tctttcgcaa
     8461 gaactcaaat tttattgaga tttggtctcg tttctttaca ttcaaagaaa atctggtaaa
     8521 attaagatag aaaagaggtg ttctttatgc gatatatcgt tacattattc tgggctgtcg
     8581 ttctaggtca agtagtcggt tatattggtg ctgcattaac aagcggaaca tatgatttta
     8641 ctttgacaac aatcatttca ttcattgcgg gtgtcattat ccttttgatt ggtgcagttg
     8701 cgccaagaaa agaaacctct gcccattcgt aaaaaaacag ccaagagctt gagatttctc
     8761 aagctctttt ttattttcta ctcctcacca ccattataat ctgctgcgaa gaactttacg
     8821 aaagttgaat aaagaaagaa gaatatttga cagaacaaac aaacttgtca caataaaaac
     8881 agcactgtaa ttataagcat gcgcgactgt cgatcctagc atgggaccta aaacttgtcc
     8941 aaagttgcta aacatctgat tgtagctata gattcggctg actccttctt gaggcgtaat
     9001 cttactgatc agtgtattga cagaaggcat caaagcgcca gttgaaaagc ctaaaataaa
     9061 gcgaagtata cctaattgga gcggtgtagt gacgaatgcc ataggtaaat aacagcaaaa
     9121 tgataaaatg agtcctccaa ttagaacttt ttgattccca atcttatccc ctagttttcc
     9181 tagtttcggt gaagaaaaga cagcggaaac accagctatc gaaacaatca agccgctgac
     9241 aaaaaggata ttttctgtac ttccgctcaa ttcacgaata tataaggtca aaatagggct
     9301 gatcgtagtg attcctatct gtaaaatcaa ggtcgtaatg aagagaccga tcaaaataga
     9361 gagatgatcc atttttgaaa aaatttcttt ggtgcttatc agatcttttt tctcgattgg
     9421 atggaaatct tctttgacta agaaaatggt caataccgtt gtgatcatca acaaagcccc
     9481 tgtgatcaag aatacatttt ccataccaaa ccactgagcc agtgcaccgc ccattgaagg
     9541 tccgatcaga tttccagcaa tcgctccggt agacaatgtt cctaacgccc atccgctctt
     9601 ttctctaggt gcctgtgaag caatcatcgc tgtggcattt ggaatatatc cagacaaaat
     9661 cccattccaa aaccgcatga tcaaaagcca atacgcgttt ggtacaaaag ccaaagatcc
     9721 cattgttaat gtcatccctg ctgctgcacg gatcatcatg agttttcggc cttttcgatc
     9781 agctagattt ccccagattg gtgcaaccac ggcagatgca aaagcagtca cagagattgc
     9841 tagtcccgaa aacaattcga tttgatcttt tggtgttcct agttgctcaa cataaactgg
     9901 tatgaatggc ataactaaac taatacttgc accagtgaaa aaacagccaa tccacgcaat
     9961 cactaaattt tttctccaat taatctccat ctatcatccc tctttcgtct cttttatcat
    10021 acctattttc gaataaacaa gcaacgatct cgccagtaaa aagagaaaaa tcccgcaaag
    10081 gtcattttat atgtaacgtt ctttttatgt aaaacaaaaa gagatcagaa caaatactgt
    10141 tccaatccct tctctttagt taaattgttg ctagaatgat gaagttgata atgaataaaa
    10201 tatcaacgat ccacaaagca acagaaactt gattgtattt tcctttgatt actttcacaa
    10261 ttgtatagaa aataaatcct gctgcaatcc cataggaaat gctatagcac aatcccataa
    10321 agatcgatgc aaagaaggcc ggtaaagctt cttccatatc tagccatttg atgtctgcaa
    10381 aagaagccat catcattact ccaactaaaa tcaatgctgg cgcagttgct tgatttggta
    10441 caatggcgat cagtggagag aataaactac ttaatgcgaa tagcactgcc actactactg
    10501 aagtcaaacc agtacgtcca ccggccccga tcccagctgc agattcgaca taagttgttg
    10561 tattcgatgt accaaagata gcccccacag aagtagcgat cgcatcggca aatagtgctt
    10621 tatccatttt tgttttgaac ccacgaccat cttccaacgc gatctcgtct tcttttgaga
    10681 aaatacctgt gcggcgtcct gtaccgataa atgttccgat cgtatcgaaa gtatcagata
    10741 aactgaatgc gatgatcgtc atcaatactt gaggaatctt ggaagaatca ctgaataaag
    10801 attgcatgcc ttcagaacca aatgctgcac cgaaagttgt tcctaattct ttaaatgaat
    10861 tacctaacga attcgtttgc caatcaatgg aacttaaatc aacaacaccc ataaaaatac
    10921 caaggactgt ggtcgctacg ataccgataa gaatagcccc acggacattt tttacaacta
    10981 aaatggctgt cagtaccaaa ccaatcacag ccaataagat aggagcgttg tcaaagttgg
    11041 ctaacgcagg gacgattcca ccatttatcg taacatttgt cgcttttccg ccttcaacga
    11101 cagagctcga aatagctgac tggtctgctg aaaaagataa gaatcctgca tttttgattc
    11161 cgacatacgc aacgaaaata ccgatcccgc caccaatcgc atgttgaaga ctttcgggaa
    11221 tcgcccgaat aatcattttt cgaatatttg tgacagtaat aaaaatattg attaatccgc
    11281 aaataaacac cattgccaag gcttgttgcc aagaataacc aagcccaaaa acgaccgtaa
    11341 aagtgaaaaa tgcgttcaat cccataccag gtgcctgagc atatggtaca tttgcgaaca
    11401 atcccattac cagcgtacca ataatcgatg caatgattgt cgctagaaat actgcttgga
    11461 agggcatacc tgatgctgac aaaatcgtcg gatttacgaa taagatataa ctcatggcaa
    11521 agaatgtcgt tactcccgcc attatttcag ttgatacatt tgtattgttt ttctttaaac
    11581 cgaaaaactt ttccataaaa agttccactc cctgaat
//
LOCUS       DAFLWC010000090        11605 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.092, whole genome shotgun sequence.
ACCESSION   DAFLWC010000090 DAFLWC010000000
VERSION     DAFLWC010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11605
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.092"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(105..629)
                     /locus_tag="L1V17_002375"
     CDS             complement(105..629)
                     /locus_tag="L1V17_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1237113.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="L1V17_002376"
     CDS             complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="L1V17_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBN1237114.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(1218..2198)
                     /gene="pta"
                     /locus_tag="L1V17_002377"
     CDS             complement(1218..2198)
                     /gene="pta"
                     /locus_tag="L1V17_002377"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HBN1237115.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(2351..3031)
                     /locus_tag="L1V17_002378"
     CDS             complement(2351..3031)
                     /locus_tag="L1V17_002378"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBN1237116.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            3157..4026
                     /locus_tag="L1V17_002379"
     CDS             3157..4026
                     /locus_tag="L1V17_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1237117.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            4052..4567
                     /locus_tag="L1V17_002380"
     CDS             4052..4567
                     /locus_tag="L1V17_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237118.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(4614..5207)
                     /locus_tag="L1V17_002381"
     CDS             complement(4614..5207)
                     /locus_tag="L1V17_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1237119.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(5232..5411)
                     /locus_tag="L1V17_002382"
     CDS             complement(5232..5411)
                     /locus_tag="L1V17_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237120.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(5488..5997)
                     /locus_tag="L1V17_002383"
     CDS             complement(5488..5997)
                     /locus_tag="L1V17_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237121.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(6093..6473)
                     /locus_tag="L1V17_002384"
     CDS             complement(6093..6473)
                     /locus_tag="L1V17_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBN1237122.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            6803..7552
                     /locus_tag="L1V17_002385"
     CDS             6803..7552
                     /locus_tag="L1V17_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HBN1237123.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(7736..9013)
                     /locus_tag="L1V17_002386"
     CDS             complement(7736..9013)
                     /locus_tag="L1V17_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237124.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(9092..9736)
                     /gene="pcp"
                     /locus_tag="L1V17_002387"
     CDS             complement(9092..9736)
                     /gene="pcp"
                     /locus_tag="L1V17_002387"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBN1237125.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(9935..10879)
                     /locus_tag="L1V17_002388"
     CDS             complement(9935..10879)
                     /locus_tag="L1V17_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBN1237126.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(10881..11567)
                     /locus_tag="L1V17_002389"
     CDS             complement(10881..11567)
                     /locus_tag="L1V17_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBN1237127.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
BASE COUNT         3304 a         2461 c         2044 g         3796 t
ORIGIN      
        1 tattcaaaaa aaatggactg cgacacgact tttgtcacag tcccttcgtg tgtttttctg
       61 ccttctcaaa aggatgacag tttctcactc ttttcctatt tcttctattc aatcaaataa
      121 ctcattttat atacatctaa aaattcacct agatctgttc ttgcccctct aggcatgacc
      181 gcttcgattt ggaagcccat ttttcggtaa aggtgtacgg ctctttcatt acgaacttga
      241 acgtcaagct ccaatcgaaa aagtacaccc atttccttcg cccaactgat gatttcttct
      301 agcataagag tgcctagtcc cattccccaa tattcctgca gaatactgat accgacttct
      361 cccacgtgag acaaacgaaa ttgactgtct gccttgacag atgctgttcc aataatcgtc
      421 ccttcataga ttgcaagcag caataaatta ttattgcttt cgtatatata atccaactct
      481 tcttctaagg tttctggtgg taacaggagt tctgcttcat ccaaaactaa aaattctgtc
      541 tccttattaa cttgtcccat catcaaaaga atgtcttttg catctcctgg cactgcttcc
      601 cgcaagatga tcccaacttc ttcactcatg attttcagcc catttttcta gaattcgctg
      661 tttgaaggtt tcactttgct ccccgtatga gattagtttc acataccgct tttctaaatc
      721 tgtatcactt ttttctaaaa tcagttccaa ataatcctcc ggcagtgctt cttctaatag
      781 atttccccat tcaacaacgg aaagcccatc accttcaaaa tattcatcta accctaaatc
      841 tgctccgcta gctgctaccc gataaatatc catatgatac aacggaatcc gaccttgact
      901 atattctcta ataatcgtgt atgtcggact tttgatcatt tgcgttatcc ctaatccttg
      961 ggcaattcct ttcgtcaacg ttgttttacc cgcacctaga tcaccagtca atatcagatt
     1021 gtcacctggc attgcggaat gaccaattgc ctctgcgaat tgttctgtca ttgttaatcc
     1081 tgatagttcg atcatttttc atcttctccc gctcttcttt ctttttgcca gtatatcgcg
     1141 taatgaagtt tttttaaaga aaaaatgaac tagtcaagaa cagcagctgc tgtttttggc
     1201 tagttcgcgt gtatttgtta atcaatcaat gtttgtgctg ctgtgataat cgataattta
     1261 tatacatctt cttcatttgc tccacgagac aaatcagaaa ccggtttgtt caagccttgt
     1321 agaattggtc cgattgcttc aaagttaccg aaacgctgag caattttata gccgatattt
     1381 cctgactgca attctggaaa tacaaagact gttgcttgac cagctacttc tgaatctggc
     1441 gctttcagtt gtgcaactga aggaacataa gaagcatcaa attgcaattc gccgtcgatc
     1501 atgtattgtg gcgctagttt tttagcgatt ttagttgctt caactacttt gtctacttct
     1561 ggcgatttcg ctgagccttt tgtcgagaag ctcatcattg ctacttttgg ttcgatatcg
     1621 aacaattctg ctgtttttgc agaatctacg gcgatttcag ccaattcttg cgcagttgga
     1681 ttcacgttga tcgcacaatc cgaaaagaca tatttttctt gatctcttcc acgtaccatg
     1741 atcatcgctc cgcttgtccg actgatgcca ggctttgttt tgatgatctg aagtgctggg
     1801 cgaacagtgt cgccagtcga atggatcgct ccagagacca ttccgtctgc aatccccata
     1861 tacgtaagca tcgtaccaaa gtaattcaca tcttttaaaa tcttttctgc ttgttctttg
     1921 gatgcctttc catttctacg ttcaacaaaa gtatccacca tttcatccca cttatcgtaa
     1981 ttatcagggc tgatgatcgt aaagctagat gttttgattc ctctggcatg cgctgcattt
     2041 cttatttctt cttcgttccc tactaaaatg ggttccacaa gttcttctgc tttcaaccgg
     2101 gcagctgcgc ctaaaatacg agcatcagta gcttccggga aaacgatttt gatcccacgg
     2161 cgaacaattt taaatcttaa actatcaaac aattccacaa gatgacctcc agacgttttt
     2221 atatgtatta tcatacacta ttccagaaaa aaagaacagt ttattttatc tgtatcagtc
     2281 aaaaatgctg gaaaaattaa gtttttcaca tacaaagcga actgcactat aacaggaaag
     2341 cgctgtttta ttacactgtt tcaggcagtt gccaatcaat cggttcttct cctaacgcaa
     2401 ggagcgcatc attcgttttc gagaagggtt tggaaccaaa aaagccacga cttgcagata
     2461 acggactggg atgtggagat gttatgatga tatggcgact cttatcgatc attttgattt
     2521 tttcttgtgc cggttttccc cacaagataa acacgattgg tttttcccgt tcatttaatt
     2581 tttcaatgat cgtgtctgtt aatctttccc aacctttccc gcgatgagaa tacgcttgcc
     2641 cttcccgaac ggtaagaacg gtgttgagta aaaggactcc ctgtttagcc catgacacta
     2701 gatttccatg ttgaacaggt gcgattccaa gatcatcata aagctcttta tagatatttc
     2761 ttaacgatgg cgggatcttt acgccaggtt gcacagaaaa agataagcca tgagcttgat
     2821 tttctccatg ataaggatct tgtcctaaaa tcaccacttt aacttcttca taaggagtca
     2881 attccaatgc ttcatagata tgatacatat ctggatggat cttttgggac gcatattctt
     2941 tttttaaaaa ttctcttaga tgcagataat aatcttttga aaattctgag gacaaaactt
     3001 cttgccaact gttatgaatg atttctttca aaaactccac ctcctaataa aaagaataac
     3061 tcacattttc ttcaatcaca agggacaatc ttcaccctca gcacttgatt aatatggtaa
     3121 actaggaaca agaagcagaa aggaacgata atcattatga tcaaattaat tgcatcagat
     3181 atggacggca cattattaga tgcccatatg agtgtttctc ctgaaaatgc cgaggcgata
     3241 cgttttgcaa atgatgccgg tgttgagttc atggtcgcta ctggtcgaaa ctatcaagaa
     3301 gctcgcgcag ctttagatga ggtaggaatc gattgtgcga tgatcacttt gaacggggca
     3361 caggtatttg ataaagaagg aaattcattg tttaccgtgt cgattccaaa taatcaagca
     3421 atctctgttt tagatattct agatgctaac ggtatttact atgaagtagc aaccaacgat
     3481 ggtctttatt ctgaaaatca agcgaaacga attgaaagtt ttgcttccat ggtggctacc
     3541 catttacctc accttacgta taaaatggcg attgccatgg cctcagctaa gctggagtta
     3601 ttgcacatca catacgtgga cagtattcgt gctattttgg aagaaaagaa tctggaagtt
     3661 ttaaaaatta tttgttttca tacagaaggg ccagctgtat taggtccagt tggaaagcag
     3721 atttctcttt taggcgatct agccgttact tcctctggtc aaaacaatat cgaagtgaac
     3781 cataaaaacg ctcaaaaagg aattgctgtt gcccatgtcg ctcacgagcg tgggatttct
     3841 ttagaagaag tcatgacgat tggcgataac ttcaatgatg tcagcatgct gcaagtagca
     3901 ggagtcagtt tcgcaatggg aaatgcagaa atcgaagtaa aagattatgc caaatataca
     3961 acggacacaa accttgaatc tggcgtagga aaagccatat tgcgcgcgat tgcagaagac
     4021 ttgtagtttt atctagaaaa gagggatata gatgtcagaa tttttcattc aggaaaagca
     4081 gcttggacgt gcaactcgga caattgtcaa aaacgaaaaa ggacattccc tgtttttgat
     4141 ggttggtcgc tggggaacaa agggcgatgc attgtctctt tatgccatga atggcgatct
     4201 cgttgctcac atcaagcaga taagcctgac attcggtacg cgttttgagc tgtataaaga
     4261 gttcgaaaag gtgggaacca tgcagaaaat attcaattgg cccggtgact tttattatat
     4321 tcgtagactt cactggacag tccaaggtga tatctataat catcaatatc aaatccatca
     4381 tttcaatcag caaatcatga aaatggataa agcaacactt ttttcaggag attactatgt
     4441 attggatgtc tcaaatgatg aagatgctcc agtttgtatt tgtattgctg cggttttaga
     4501 ttactggctc taccgtaaag acaaaagtcg cgataagcct gtttcttacc gacttaactt
     4561 aagttaaaaa gatgtacctg aaatgcggaa atacgcattt caggtacatc tttttagata
     4621 ttcttttgca tatgatcata aagatgacca ctgatcatcc gctgaccgac aactttgaag
     4681 tcatggcgtt cgtataattt tttagccttt ggattttttt catccacact tagaccgatg
     4741 acggagcgat tagctttctt cgccaattta ggtaatgctt ctaataatcg cgaaccgatg
     4801 ccttgtcctc taaaatcttc tgatacactg atagagtcca aataccattc gttgggaaac
     4861 gtttctttat caatgaacaa acgtgtagac gcatctagct gatatttctc taagataggt
     4921 accagtggct gatcgatgat tgattcttct tcatctgtat aaccgtaagc aactcctgca
     4981 actttaccgt ctatttcttc tacgatacct cgtgaataac tgtaacgata atttggatca
     5041 gtgattgctt cttctaaaat ctctaaagtc ttttgttccc ctgtctgctt caaaaatggc
     5101 agttccatat cttttagaat cactaagatc aatggggcga tttctggagc atcttctttt
     5161 ctcgcaaaac gaatcatagt ttcctctcct tttctccatt ctaacatgca gaaaaagaaa
     5221 tcgcaaaatc gttattttaa aaaatcttca atcttttcag taatgaaata accatgagta
     5281 acgattcttg ccgcttcagt tcggcaataa gggcagacga ctggcatttc tttatcatta
     5341 tgttcgacta cattattgac ttcttcgtat gcaaattttt ttccgcaatt agggcatttc
     5401 attttttcca tgttatctca acttcctttc atctttactc tcttagctta ctcttatatt
     5461 gtaaaaaaga gaagcaatat ccttcttcta tgcagatatc catacctgac ggtcctgttc
     5521 tccatctatt aatcggactt tataataagg acgttcatct ttgactagaa gtgtccactc
     5581 tttcactttt gcttttttcc cgtagtagct gactgcttcc ttcatcgctg cttgcggttg
     5641 tttgaactct tccgtttttt ctatatcaaa aagatgttct gcggcctttt ccgtgtcatt
     5701 tcgtacggtt gttttcccag tggatggatt gactgctatg acttgtcctt cacaaaaaaa
     5761 ctggtattca tatgttgcat tcgtaggatt ctccaaatct ttttcaactg caaaatgaat
     5821 agcagatatg ttatgttctt ttgtttcgtt ttttacgatt gctgctgctt ttttcaatga
     5881 gatccgatat tcctggtcac taatatcatc catgtgaaaa gcggcattga gcagtcccgt
     5941 cataccggta atccctatta cgatgagggc agcaacacca aacatcattt ttttcattct
     6001 tcattctcct gtttcttttt tttaaagaat atcaagaaat gaacgaatga aaaatcgaat
     6061 gaaacgaaaa aaaagtgaca attttgttat ctttattcgt gcagttctaa tggcaatccg
     6121 tctggatcaa agaaaaacgt catttttttt cctgtaaagg tatcttctct aatcggttct
     6181 gattcgatcc ctaaggactg caattctgca attgtttctt caatatcgtc tactttgaaa
     6241 gcaagatgac gcaagccaca agcttctgga tagtttggtc gttgtggcgc attagcaatt
     6301 ccaaaaatct ccaattcagc acttcctagt ttcagatcta atttatagtc atctcgttct
     6361 ttgcggtaat tttctctgat tacttcaaat cctaatttat taacataaaa atcacgtgat
     6421 ttctgataat ctgaaacaat gatggctata tgatggatcg ttgtaaggtt catatgagca
     6481 ctcctattct tcgtttaagc tcggatctat attaatctcc agttccattg taaatgtgtc
     6541 agattgaaaa aaatagctgt ttttcctttt tataagaaaa aaggcaaaaa aaacagaaag
     6601 taggtcctcc aagacactct tcctgttccc aatataataa atgaaagtaa gaaattatat
     6661 tttcaagaaa acaaacagaa aattatcata acacaaatta tttataattg aaagactagt
     6721 tttttttcaa gaaaagcata caatagattg tgttagtaaa tacagaacac actacattta
     6781 gtgtcttaag gagtcctcat acatgaagtc atattttcag tttttagctc atcagctaaa
     6841 aggctggccg caacaaaatt attatctttt ctttttcagt cttggctgcc aggtcatgac
     6901 tcttgtcaat agtcccatca cttggctgtc cgttattaca tttatcggta ccacgcttgg
     6961 tgtattgtgt attttatcca tcaatgcggc aaaatcagtc aacggtattt taggtatttt
     7021 gtctgcgatt tgttttatta tcgttgggtt ttcagcaaag aactatttaa gtatcggtga
     7081 acagattgct tatatgatca cattggatat ccccgtattg ttaagtaaag aatggaatca
     7141 taatatggct tcaaaaatcc gaaaattcac tggaaaaagc tggtttatcg caatcatcag
     7201 tactttcctt gtctatcttg tttcaggatt cctgattggt cgttatacag atgatcctcg
     7261 gccgtgggta gatgccattg ctttttctat tagcttgact gctggtatca tcagtttctt
     7321 gcgttacaac aaccaatatt actggtggtt agcttcaggg cttgctcaaa tggtcctttg
     7381 gtatatttca tttacgcatg gatctgcaag tttggcgatg ttcgtgaaca gctctgttta
     7441 cttgctgaat gatgtccttg catttaccgt ttcaccttgg tataaccaaa aagaacgtga
     7501 acgtatgcaa aaaatggaag aagaatacta caacgcacaa caacacgcat aaaaaaactg
     7561 agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta taaacggcgg
     7621 aatcagaagc aactccttcg gaaataagct gaaattcaca aaaatttgaa aagcaatttt
     7681 cgtgaatttc ttcttatttc ttggagttaa acgcttctgt cccagcctct attttttata
     7741 gtaattcctt cagatacttt cttgcctcat cattgaaacg cagtgattct tctaacttct
     7801 gataatattc caacgcttgt ttctgagctt cagtaaaacg ataatgtttt cctttccatt
     7861 tgtcgattgt ctcttgcaca tttccagatt ggatatcttt cactactagt tgccattttt
     7921 cttttgagac tgtacggtct ttcttatcag cagattgtat agcttctcgt tctttacgca
     7981 atacttttaa aaaaccattt ctgactatcc gaggaatgct gtcgaagaac ccttctgtaa
     8041 aaccatagcg acaatattgc ttccaaataa atagatagat ttttggttgg atgaatcgtt
     8101 ggtttttcgc aaaatattcc atctgagcag tgacttctgg tgttcgttga cgttttgtct
     8161 ttctcaacac ggaaataaat gtttcaaaat aagcattagg atgtactggc acttcttcat
     8221 atacgatgga ttgccaatct ttacgtaaaa atgcgcgata gttgatcaag aattcttcta
     8281 catcctttac taattcttct gcaaagtcgt caaatagttc tttttttatc tgtcgctttt
     8341 ttgactgccc attgatgtgt tcacttattt tcttgatttc attttccaat gcttgataat
     8401 ccgctatgta aatcggcatt tctacttggc gaaattctgc gagccgctga gctaatttta
     8461 tatccggtaa atatggctgt ttcatccgac gattttggta caagacaaaa cagtattttt
     8521 gccatagtcc ttcaggaaaa tcgatattct tctgcttaag ccataataat tcgtctaagg
     8581 ccagatcaac ttttgtcatt ccctgatgga tcgaagctgc cactgtcgga gagacatgca
     8641 ggtgatcggc aaagtggttg atgcctagtt ttaggatctt tccggttttt ggcgatttaa
     8701 cgatgtattg cacttttaat tctctaccac actcacaata caatttttgc tggcttcgtt
     8761 ttgttcgaaa aaacggattg atcttgaagt cagaaaacac ccaatctgtt gcagctaaat
     8821 aatgttcttc cataaaacga gagctgatta gatatcggcg gtgcttatcg actagttccc
     8881 gctgtttttt cgttaatttt gcatagatct cccaacgttg actgcttgtg tattgtttag
     8941 aaattttgat gggatagctt ttgctgattt cttttggaaa ccattcttca aagacggatt
     9001 gccattcttc cacggctgtt tctttccttt ctaattacaa aaagctggct actaacataa
     9061 cgttagcaac cagccagtgt ttcttgctaa attagtgagt tgttccggca tttccggaaa
     9121 tatcttcttt attttctact gctgcttcaa ctgcataagt caaagaagaa gcaatgtctt
     9181 ctaaagacat agaaggcgta cccactggac gatcgatcac ttgatcgggt gagaatggca
     9241 cgtggatgaa cccacctcga attgccggga attgtgtttc gatcaaatga agcaaacgat
     9301 acatgatatc attgcagaca aatgttcctg ctgtataaga gatgtacgct ggtagaccat
     9361 gatcttgtac attttttgtc attgctttga ttggcaatga ggtaaagtaa gcggctggac
     9421 cgttttcttc taaagccgta tcgaatggct gatttccttc attatcaggg attcttgctt
     9481 ctgctagatt gattgcgaca cgttcgaacg agactgctga ccgcccacct gcttgtccga
     9541 cacagatcac gacatctggt tggtgctgtt ggatggcttc tttgactact tgactgcttt
     9601 tttcgaatac ggtcggtact tccactttga tgatttcagc accgctgatt tcatctggca
     9661 ttttttttac tgcttcatag gctggattca ctttgtcccc accaaatgga tcaaaacctg
     9721 ttactagtac tttcatctgt tgttcctccg tccgattgat ttaacatatg gttatctttt
     9781 atcataccat tttccttgaa cagcgtaaat aaaggaaaca atagtttaaa taacataaca
     9841 gatcaaactt aatatattct tataaaaaaa tagtgttcca ctacaatgtt agaagaggtt
     9901 gcgacaatta ttctgtcaca acccctctct tctattattt aaatagaatc atataagcaa
     9961 tttggaaaac tagcataaat aacgcaataa acaactggtt tttgatcact ccgtatttgt
    10021 ctttcatctc cagcatcgct acaggcacga tattgaagtt agcagccatc ggtgtcagca
    10081 gggtcccaca aaaaccgcaa gtcaatgcaa ccattcctat taacgctgga ttcgctccat
    10141 gactaaatac gaatggtgca ccgatcccaa ccgtcatcac ggtgatggcc gcaaatgcat
    10201 tccccatgat taccgtaaat atcaccatgc caagagcgta aatgatgatg ccgatgttca
    10261 catttccttc tggaacgatc gtacctactg cattggaaat cactgtccca actccagcgc
    10321 ttgtaaatac cgcacctaga gaagctaaaa gcattggcaa catgcttaac ggccctactg
    10381 tgcccagcat atctgctgca tcatctaaaa atgtacttgg tcgattatct cgagaaaaga
    10441 acatcaagat tagcatggct gcaaaaacac cgacgcccac gccgactaaa gcacctaaat
    10501 tggtaaatag agcaaacaag atcgcaaaga caccgatact caaagctgga ataaaaattt
    10561 tcattcctag tttgtctgac attttttcca tatattcttt tgatggaagc cggctttctc
    10621 ctttgctgac tttcttagca attgctggta tggtcatcgc aaagatcaag ccaccgttca
    10681 cgattgccgg aagccatctt cctcctgcaa taactacccc taagaccgtc cagaaaaagg
    10741 ctgacccata acgatgagga ttggttttat ctgttaaatt tcttactcca gtgtaaatca
    10801 atacgagtcc catcacgata taaaggatct ccagtaattt atcgcctaat aaaatatcag
    10861 gatttgtaaa aaagtccatc ttattgcccc tttcctggat aatatttctt cgctaatttc
    10921 ttttctttaa gatagaagta gacacttgcc acaactaaag ccgtgatagc cactggaact
    10981 tccactaaag caagctgtcc caatgttacg tcatatccta gatctttcag tgttgattgg
    11041 actagcaacg cccctgctcc tccgatgaat agtacttggc caaagaacca gcagacattt
    11101 tccatagctg aagccatacc ttttagttct tcttcatgct taggatggac ttctaaccct
    11161 tttgattcga tggtccccaa tgccatcggt aaaatgattg gacgaacaaa tccagcaact
    11221 ccaccaaaac tcacgttaaa agccgcaaag atcattcgaa agatcccata aatatctaca
    11281 atcataccag cagatacttt cttgaatcgc ttgatcaagg aagccgctga ttctttcaga
    11341 ccatttcttt caagcgttcc tgttgccaac ataatgatga taaaaatcgc catcccgcga
    11401 ttgtttacaa aacttgtacc taaaagttct aacattcctt gaatgccaag accgccagtc
    11461 aaagctgtaa caactaaagc aaccattacg atcaatatcg agtctaattt aaatgcaaac
    11521 ccgagaataa caatcaagac gcctaaaagg ctaagataat tttccatata ttttcctcca
    11581 taaaatgaca atattttttt aatta
//
LOCUS       DAFLWC010000091        11563 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.093, whole genome shotgun sequence.
ACCESSION   DAFLWC010000091 DAFLWC010000000
VERSION     DAFLWC010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11563
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.093"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(275..760)
                     /locus_tag="L1V17_002390"
     CDS             complement(275..760)
                     /locus_tag="L1V17_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBN1237128.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    850..1195
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1240..1881
                     /locus_tag="L1V17_002391"
     CDS             1240..1881
                     /locus_tag="L1V17_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBN1237129.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            1900..2535
                     /locus_tag="L1V17_002392"
     CDS             1900..2535
                     /locus_tag="L1V17_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBN1237130.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            2553..3368
                     /locus_tag="L1V17_002393"
     CDS             2553..3368
                     /locus_tag="L1V17_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBN1237131.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            3687..5123
                     /locus_tag="L1V17_002394"
     CDS             3687..5123
                     /locus_tag="L1V17_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBN1237132.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKSSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            5312..7744
                     /locus_tag="L1V17_002395"
     CDS             5312..7744
                     /locus_tag="L1V17_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBN1237133.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQLSFVPI
                     DSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQDYELPT
                     VDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEVQPAVG
                     VKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIEAQPNH
                     PDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRAKPHEV
                     KLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAATGVRNI
                     SGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMARAAGI
                     HMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGDMLFLP
                     MGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQPQDELF
                     EEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKVFIEQE
                     ETSETLPDDNDM"
     gene            7974..9041
                     /gene="rlmN"
                     /locus_tag="L1V17_002396"
     CDS             7974..9041
                     /gene="rlmN"
                     /locus_tag="L1V17_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBN1237134.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(9234..10337)
                     /locus_tag="L1V17_002397"
     CDS             complement(9234..10337)
                     /locus_tag="L1V17_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBN1237135.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            10889..11437
                     /gene="aac(6')"
                     /locus_tag="L1V17_002398"
     CDS             10889..11437
                     /gene="aac(6')"
                     /locus_tag="L1V17_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBN1237136.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         3844 a         1948 c         2486 g         3285 t
ORIGIN      
        1 tagttagaat ataatatttt ttgttaaata tgactgaaat caaaagaata aaattccgat
       61 ttataatcga aaaaagaagc atttttatat atgcttcttt tttcgtagaa tcaataaata
      121 tggatttggc taactatgga agaatactcg tattagtttt cagcgttcat actagttgtt
      181 acattgtttg attggccaaa agaatttctg atatattttg tgctaaataa agaaaaagac
      241 gcttgaattg ggaaataaga aaactactct atcattacaa attttcataa actggcagat
      301 gttctaagta aacaagtatc ttttcaaagt cggaaaaatc cataatcaac gtagtggtat
      361 tgatatttgg atgaaagcct acggtatctt gacgatcaat agcagcatcg atcacgactt
      421 ggattttttt ctctttgtcg tgcatcaatg ctaatggagt cactgtacct gctggaacgc
      481 ctaggaggtc aggaagctgt tcttcagaaa caaaagataa gcgcttttct tttaattgtt
      541 cagctagttg ttttaaatcg gcgtgctttt catcaggcaa gatgacaaga tagatttgtt
      601 ttccttttct tgatttcaat aatagatttt ttacttgcgg accaggtagg gaaaaaggga
      661 catttttgac tgacgtaatc gcaggatgat cgactttttg aaaagagata cccagttttt
      721 ttagtagttc ataagcttct tgttcggttg cacgactcat cgcgcatcac cctccttttt
      781 ttattagtgt atcataaaaa agagttgaca aatgaaaaat aatcatgtaa attacacgta
      841 aagttaaaac aaatgacatc gaaaagaaga gtagccgtta ggtgttttta gagagtctct
      901 ggttggtgga aagaggcagc agttaaccgt gaaacacatc ttggagtcga ttttctgaag
      961 cgtatagtag gaaaatccgg ggagcccgtt acagctgcgg tcgttgctag atgaccagat
     1021 aaggctggct tttccgtgag gagtcggtaa aaaaaggtgg aaccacgtga ttaacgtcct
     1081 ttgatcttcg gatcaaagga ctttttgttt tcatctgaac ggcaacgact gtgtgaggtt
     1141 ttttctgcaa ggaaaaaata aacagaggtg gaaccacgta taatacgtcc tcttggcatt
     1201 tgccaagagg atttttttat tttaaaggag gaaaagaaga tggagtattt gattgaagtt
     1261 atgccgcaat tattagtagg agcactcaca acattgaaat tatttttatt taccttgatt
     1321 ggctcattac cattagggat tgttttagca ttaggattgt ctttgcattt taagccgcta
     1381 cgctacttgc ttcaaacata tgtatgggtt atgcggggaa caccgctgtt gttgcaactg
     1441 atttttattt tttatgggtt gccgacgatt gggatcgttt ttgatcgttt cgaagcagca
     1501 ctcattgcct ttatcttaaa ctatgcagct tattttgcag agatctttcg tggagggata
     1561 caatcgattc ctcaaggtca atatgaagca gcgcaagttt tgcaattaag tccctttcaa
     1621 acggtgacga aaatcgtcat cccacaagtg acaaagattg ttttaccttc tgtagggaat
     1681 gaagttatca acttggtcaa agattcttcc ttgatctata tattaggttt aggtgacgta
     1741 atgcgtgctg ggaaaatcgc gatggaacgc gacgcgactt tactgccttt gctaggcgtg
     1801 gcaatcatct atcttacatt gactggtatt ctaacaatcg taatgaaaca agttgaagga
     1861 aaattaaatt attaccgcta actgatagga ggaagaaata tgattgaatt gaagaaagtg
     1921 aacaaagcat ttggtgaaaa aaaaataatc aaagatttga atctaatcat tccagatggg
     1981 aaaacattag ctatcgtagg tccttccggt ggcggtaaaa ccacgctttt acgtatcttg
     2041 gctggcttag aaagttctga cagcggagaa ttttatttag acggtgtacc gttcaaccca
     2101 ttcgagctta aaatgaaaga acaagttgta ggagtcgtat tccaagactt ccagctattt
     2161 ccacatctga atatttttga aaacattacc ttagcaccaa aaatggtatt gaaacagaca
     2221 aaagaagaat acaccaaaaa agcagaagaa ttagcggctt cattagggat tagtgattta
     2281 ttgaatatct atccttatca gctttctggc ggacaaaaac agcgggtagc gattgccaga
     2341 gcattggcta tgaatccacg ggtattggct tatgatgaac caacaagtgc tttagatcct
     2401 gaattacgcc agcaagtcga gcgtttgatc ctatcattga aagaagatgg ggtaacccaa
     2461 attattgtca cccatgattt agtatttgca gaaaatgtcg gtgatcaatt actaaaagtt
     2521 tccccaattc attaagaaag gagaagatag agatgaaaaa aaccagtttt ctattcgctt
     2581 tgatcgcagg tcttcttctt tttgcaggct gttcgaacaa aaaaacttca gcagataatt
     2641 gggcgactat caacgaagag aaaaaaatcg ttataggttt agacgataca tttgttccta
     2701 tgggatttag agataaagac gggaagctca caggatttga tattgattta gccaaagcag
     2761 tctttgaaca atatgggatt acggtagact ttcagcccat tgactggtca atgaaggaat
     2821 ttgaactgaa caatggaacg atcgatttga tatggaacgg ctattccaaa acgccggcaa
     2881 gagaaaagaa agtgcaattt acaaaacctt atatggaaaa cgatcaagtg ctgatcacac
     2941 ctaaagaatc aggaatcaca aactttggac aaatgaataa taagagatta ggtgcgcaaa
     3001 atgggtcatc tggttatgat gtatttacga aacaaccaga agtattaaaa gagatagtca
     3061 aaaaccaaga tgctgttttg tatgatagtt ttaatgaagc attgatcgat ctgaaaagca
     3121 gacgggtcga tggtctgctg atggataaag tatacgcaga ctattatttg aaacaaagaa
     3181 acgaactaga agacttcaac ataacaaaag gttcttatga gagtgaggat tttgcagttg
     3241 gtgcacgcaa gtcagatagt acattagtga aaaaaatcaa tgaagcccta gatcaactag
     3301 agaaaacagg tgaattccaa aaaatatccg ataaatggtt tggcgaagat gttacgccga
     3361 gaaattaaca aataggggac tgtgacaaaa gacgtgtcac agtccctttt tccgaataaa
     3421 cagtgttctc ctgccaactc cttgtgactc ggagctgaat ggcaggctca caacctcttg
     3481 gtaaacggtg ttcaaaagcc agtttttcgg tattaagcca aatttatgca aaaatgtaga
     3541 aagccatttt cacaaaattt ttcttactac tcgaaactaa gcgacttttt cacaacctcc
     3601 tttacataat tttattttgt tgtggaaggg gtttcgtgtt attctaaaag aggaacgatt
     3661 gaaggttata ggaaaggaag agatgaatgg aacacaaaga acttacctca tttccaaaag
     3721 attttctgtg gggctctgct tctgcagcgt atcaagtaga aggagcttgg caagaagatg
     3781 ggaaaggaga atcagtctgg gatcgatttg tacggatacc tggaaagaca tttaaaggaa
     3841 cgaacggtga tttggcagta gaccactatc atcgttataa agaagatatt gctttaatga
     3901 aagaacaagg tctgaaagct taccgcttct ctgtagcttg gacacggatt tttcctaatg
     3961 gacgaggaga agtcaatcaa gctgggctcg ctttttatga gagattgatc gacgaattga
     4021 ttgaaaacga tattgaacct atgttgactt tatatcattg ggatcttcca caagcattgc
     4081 aagatgaata taatggttgg gaatcacgtc agatcattga agatttcact cattatgcag
     4141 aaacattatt tgaggcattc cgcgggaaag tccattactg gattagtttg aatgaacaaa
     4201 atatcttcac ttcattaggt tatttgttag cagcacatcc gccaggtgtg acagacccga
     4261 aacgaatgta tgaagttaac catattgcta atttagcaaa tgcatctgtc atcaataaat
     4321 ttcacgagtt agaaatgcct ggaaaaatcg gaccaagctt tgcgtatacg ccaaattatc
     4381 caattgacag taatcctgaa aatgttctgg ctgctgaaaa tgcagaagac ctgatggcca
     4441 attattggat ggatgtctat atgtggggaa aatatccgat tgctgccatg aggttcttag
     4501 aagaaaaagg atgggcacca acgattgaag ctggcgatgc agaattgcta gaatctgcta
     4561 aaccagattt tcttgggatc aattactatc aaacggcgac gaatgcattc aatccattaa
     4621 acggagttgg tgctggaaaa atgaatacga caggaaaaaa aagttcatca gaagaaactg
     4681 gagttcctgg aatgtataaa aaagttgaga atccatttgt cgaacgaaca aattgggact
     4741 gggagattga cccagaagga ttaaggatcg gactgcgtcg tatcacaagc cgttaccgca
     4801 tgccggtact gattacggaa aatggcttag gagagtatga caagttgaca gaagataaac
     4861 aaatccatga cgactatcga atcaattact tacaaagcca cgtcaaagcc atcaaagaag
     4921 caatttcgga tggagcagaa gtcctaggct attgcacctg gtcttataca gatttgctta
     4981 gctggctgaa cggttatcaa aagcgatatg gatttgtata tgttgatcaa gacgaaacac
     5041 aagaaggatc tttggaacga tataagaaag acagttatta ctggtaccaa aaactgattg
     5101 aagaaaatgg agagaacctt tagttcacat acttaaaaca agaaggtacg gctggatatg
     5161 gccgtgcctt ttcttgataa aatcatttag aaattaagaa aaactgtaaa ataagctgaa
     5221 aaatgaaaga aagcgtcagt tctttcaaac aaaactttag ttcccttact tttttttgta
     5281 taatgaaact tgatgaaatg agggataata aatggcacaa aagaaacggc ctactaaaaa
     5341 aaggaaaaag acgaaaaaaa cgaaaaagca aaaacagcag caggaacaaa tgctgacgat
     5401 tggtgttggg tttgccttga ttttatttgc tgtcttcggc tttttaaaat taggtttttt
     5461 aggaatattg attgcaaacg gctttcggat cattgcagga aatacttacc aaatcctctg
     5521 tcttttatta gccgtattag gattttggat tgtcattaag aatacagagt tttcaattgg
     5581 taaaaaccga cgctggtttg gcggcatact cttttatttc ggtatcttat tattgttaca
     5641 tgcccattta tttggcaaac tccatactgg ggaaccaaat atcatgggga cgacatggga
     5701 tttgttagcc agtgatataa aacaaagtca agtagacaat aacgttggtg gtgggatgat
     5761 tggagcaatc ctttatcatt ttacttactt cttgattgca cagcctggaa gttatttagc
     5821 agcagtgcta ttactggcag gaggagcatt cctgttcagt aatctggaag gctatcagct
     5881 gttaaatggt atccaatcaa ttggagaacg agtacaggaa ttattggaag gtgatcctgc
     5941 caagcaagct cgaaagcaag cggcaaagga agagagaatg aaacagcgcg cagaagcgaa
     6001 agaagcaagg cgcttagctg caaaagaagc tgcagaatat gagaagaaaa aagcggtgag
     6061 ccagcaaagg gaaaatactg ctgatgaatg gcaggaacca gaaaatacag agccggagca
     6121 gctaagtttt gttccaatcg acagttttca agaaaatatc catcctgcga atctagagaa
     6181 accagtacca gatacaccaa aacagaccaa tacagcagaa ggtttttcag atgagttgcc
     6241 agaggatgac ggtacctcat tagaatttga gattgaagca gaacaggaaa atcaagacta
     6301 tgaattaccg acagttgatt tgcttgattc tataccaact gtggatcaaa gtgatgagta
     6361 taaaaaaatt gaaaaaaata tcggcgtatt agaacaaact ttccaaagtt tcggtgtcga
     6421 tgccaaggtc gtcaaagcca gcttaggacc atccgtcaca aaattcgaag tccagccggc
     6481 tgtaggggta aaagtaagta aaattgtgaa cttaacagat gatatcgcgc ttgctttagc
     6541 ggcgaaagat gtccggatgg aagcaccgat tccaggtaaa tcactgattg gtattgaagt
     6601 accaaatgga aagatcagta tggtttcctt tagagaaatc atcgaagcac aaccaaacca
     6661 cccagataaa ttactagaag tacctttagg acgtgatgtt tctggacggg tacaaacggc
     6721 tgatctttcg aagatgcctc acttactcgt ggctggttcg actggtagtg ggaagtcagt
     6781 agcaattaat gggattatca caagtatatt aatgcgtgct aagccccatg aagtaaaact
     6841 gatgatgatc gatccgaaaa tggttgaatt gaatatgtac aacggcatac ctcatctgtt
     6901 gacgccggtc gtgacgaacc ctagaaaagc agcgcaagcc ttacaaaaag tagtacaaga
     6961 aatggaagaa cgatatgaaa aattcgcggc aaccggagta agaaatattt ctggttacaa
     7021 tgaatttgtt caacagaaaa acttggaaaa cggaacgaaa catccaacct taccattcat
     7081 cgtagtgatc gtagatgaat tagctgattt gatgatggta gccagcaatg aagttgaaga
     7141 tgcgattatt cgtttagcgc aaatggctcg ggcagcgggg attcatatga tcctagctac
     7201 tcaacgtcca agtgtggatg ttatcacagg aatcatcaaa gcaaatgtac cttccagaat
     7261 ggcatttgcg gtatcaagcg gtacagattc tcggacgatc attgattcta atggggcaga
     7321 aaagctctta gggcgaggag atatgctatt cttgccaatg ggtgagaata aaccgatccg
     7381 tgtgcaagga gcattcattt ctgaccacga agtagaacgg gtcgttcaat ttgttacaga
     7441 tcagcaagaa gctcattatg aagagaaaat gatgccgaca gatgaagttg aaacgacagg
     7501 tgctccagaa cagccacaag atgagctgtt tgaagaagca aaagcacttg tcgttgaaat
     7561 gcaaacggca agtatttccc ttctccaaag aagatttcgg atcggttaca accgagcagc
     7621 acgtttagta gatgaactgg aagctcatgg agttgttggc ccgtcagaag gaagcaagcc
     7681 tcggaaagta ttcattgagc aggaagaaac atcagaaacg ttgccggacg ataatgacat
     7741 gtaaaacttg tgtgatgaag ggttgaaaaa cgaataacca ataaaaagac aaggcatgat
     7801 gataccaaaa gaaaaaatgg tttttttcca tcttttctaa tacggtatga tgtcttgtct
     7861 ttttagtttt tgtgagatta aagttctatt cgatttattt gtgaagtatt gcattaagga
     7921 aatgaatcat gtatagtatg tagcgaaact ttgagaaaaa gagggaaaat actttggaaa
     7981 aacagtccat ttatggcttg acgaatgaag aattaatcaa ttggtttata gaaaacggcg
     8041 agaaaaaatt ccgagctgcc caagtttggg aatggttgta tcaaaaacgt gtaagtaatt
     8101 tcacagaaat gacgaatcta tcgaaacaat tgatcgaaaa attatcggag cattttatca
     8161 tcaatcctct aaaacagatg gtcgtccaag aagcttcgga tggtacagta aaatatttgt
     8221 ttgaactccc tgataaaaac atgattgaga ctgtactgat gagacaagaa tatggcttgt
     8281 cagtttgtgt gacgacacaa gtaggatgta atatcggctg tacgttttgt gcaagcgggc
     8341 tgctcaaaaa gaaccgtgat ctgactgctg gagaaattgt tgcacagatc atgatggtcc
     8401 aacattattt tgatgagcgc aatcttggcg aacgcgtttc acatgtcgtt gtaatgggga
     8461 tcggtgagcc atttgataat tacgacaatg taatggactt tttgcatatc atcaatgatg
     8521 ccaaaggatt ggcaattggt gctcggcaca ttacagtttc cactagtgga ttagcacaca
     8581 aaatcaagga attcgctaat aacggcttgc aagtcaatct ggctatttcc ttgcacgcgc
     8641 cgaataatga ggtgcgaaca tcgatcatgc ggatcaaccg aagtttccca attgagaaat
     8701 tgatggaagc tgtggatgag tatttagaga aaacaaaccg tcgaatcacg tttgaatata
     8761 tcatgttgaa tcaagtaaat gatagaccag agcatgcgca acaattagca gatctattaa
     8821 aagataagaa aaaattagca tatgtcaact tgattccata taatccagtc agtgaacatg
     8881 atcaatattc tcgcagtcca aaagctgatg tattgagatt ttatgatgta ttgaagaaaa
     8941 acggcgtaaa ctgtgtgata cgtaaagaac atggtacaga tattgatgca gcttgcggac
     9001 aattgcgaag caagcaaatg aaaaaaacag ttgccaaata atcgtatcct actcgttttt
     9061 tcaattacca taaaaggagc agttttctta attaaggaac tgttcaactt aaataagaga
     9121 aaagattcta tagcgaaagc tataaagctt tttttgacaa gaaaaaccct catcaagcaa
     9181 agaaatgtcc tcaatttgat gacagcctgc ttgatggggg ttttagcaat tatttaactg
     9241 attttcttat atccttgctg gctttcttgt gtagcatgat aagtttctac gtcaagaatg
     9301 gcctgtttaa atttttctcg ggtgatttca taaggcacat gtttaatatc atttgttgcc
     9361 atggctttat ctaagattgc ttctaaatcg gtcgtgacat tgagattcat gtcggttaac
     9421 gatactggaa gttggttctt tttcataaac acatagattt tatcaaacaa atcgaactgc
     9481 tgatccatca tcaataaggt cagtacacca taactgacag atgctccgtg aaggtatccc
     9541 tccatttttt ctagaacagt cgtaccgtaa tagaatgagt gtgccatagc agaattatag
     9601 ttattgttaa ctaaaacaga aaccaatccg gtagtaacaa tgatatccga aacgacttgt
     9661 tcaattgcat atgagggacg atcgtcggca ctatctttca atgcttgcgt accataagtc
     9721 aagagacgat caatgcacat ttttccgatt tggattccta atctatccgt gtagcctaga
     9781 tcatcgccac gagcagaaaa agtagattcg acttctttgg ataaagcatc gccaatacct
     9841 gcccataagt atttatcagg tgcttcggca ataattgctg tatcaatgaa ggtgtgtaca
     9901 ggtggttttg aaggaaagaa gagtccgtcc attacgcctt cttcgttata gatgacacat
     9961 accgcagtga cgggcgaaca gttcgaacca atagtgggaa aggtgaagac tggtttagct
    10021 agtttttcac caatgacttt tacagtatcg caagcacggc caccaccgac tgcaaacagg
    10081 acgtctgctt tttggacact ttcatgctgg atcaactgtt caatatttcc ataagttgaa
    10141 ttacccccgt accagagact ggcgacaacc tctatttcct gtgtcaaagc tacttttatt
    10201 ttgttttctg cctttgaaag tgcagtcttc cctccaatca gcactacttt tgtcccatat
    10261 tctttgacga ttccatttgc tttttcatac gcatctgttc caatggtata atttggtaag
    10321 aaaacacttt gactcatatt catttccttc tttcttcgtt gaaacgggtt aaaattttaa
    10381 agagtgatcg atctgactgc ggctgtagat ggagtagagg tgaacctaag acaggataag
    10441 tgatgaataa ggtggcatga acaccttgaa atcatcaata agtatcctaa aaacgaacaa
    10501 gtacaaaaac attgaaaacg acaataatga atttttgttc ctcttagtat ttctaccgat
    10561 tccctttgct tttttgtaat tatctaaaaa ttctaaaaat taagattatt atatgaaaac
    10621 aggttttatt tgtcaattca taattggttt tttttaaagc aaaagataat ctatatcatg
    10681 atgaacaaac agagtttttt cctccaattg atggctttcc tgatctttcc tattttgaat
    10741 aaagtgtttc tgtataattt tttattttat aagtaagata aataatgaaa gaatagagat
    10801 actgattggt agctaaagat ttttgagcga gaacatttcg ttttttcaaa aggactgtta
    10861 gaataagcaa gaacaagggg gaagacgtat gataatcagt gaatttgacc gtaataatcc
    10921 agtattgaaa gatcagcttt ctgatttact gagactgact tggccggaag aatatggaga
    10981 cagctcggca gaagaagtag aagaaatgat gaatccagaa cgaatcgcgg tagcagcggt
    11041 agaccaagat gagttagtag gatttattgg tgcaatccct caatacggta tcacaggttg
    11101 ggaattgcat ccattagttg tagaaagctc ccgacgaaag aaccaaatag gtactcgatt
    11161 agtcaattac ttagaaaaag aagtagcttc cagaggagga atcacgattt atttaggtac
    11221 ggatgattta gaccatggaa caacgttaag tcaaacggac ctgtatgagc atacatttga
    11281 taaagtggct tccatccaga accttcgtga acatccgtat gaattctatg aaaaattagg
    11341 ttataaaatc gtaggtgtct taccaaatgc aaatggctgg gacaaaccgg atatttggat
    11401 ggcaaaaacg attattcctc gaccaaattc tcaataataa aaagaggttg tgacagaagt
    11461 aatcagcttc aagaaataag aaggaattta cgaaaattac ttcttgaatt tttgtgaaat
    11521 tccaacttat ttccgaagaa gctacttttg gaacaccgtg tac
//
LOCUS       DAFLWC010000092        11233 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.094, whole genome shotgun sequence.
ACCESSION   DAFLWC010000092 DAFLWC010000000
VERSION     DAFLWC010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11233
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.094"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            12..84
                     /locus_tag="L1V17_002399"
     tRNA            12..84
                     /locus_tag="L1V17_002399"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:45..47,aa:Val,seq:tac)
     gene            88..160
                     /locus_tag="L1V17_002400"
     tRNA            88..160
                     /locus_tag="L1V17_002400"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Lys,seq:ttt)
     gene            168..249
                     /locus_tag="L1V17_002401"
     tRNA            168..249
                     /locus_tag="L1V17_002401"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:202..204,aa:Leu,seq:tag)
     gene            267..339
                     /locus_tag="L1V17_002402"
     tRNA            267..339
                     /locus_tag="L1V17_002402"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Thr,seq:tgt)
     gene            351..422
                     /locus_tag="L1V17_002403"
     tRNA            351..422
                     /locus_tag="L1V17_002403"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:383..385,aa:Gly,seq:gcc)
     gene            439..524
                     /locus_tag="L1V17_002404"
     tRNA            439..524
                     /locus_tag="L1V17_002404"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:473..475,aa:Leu,seq:taa)
     gene            535..608
                     /locus_tag="L1V17_002405"
     tRNA            535..608
                     /locus_tag="L1V17_002405"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:569..571,aa:Arg,seq:acg)
     gene            618..691
                     /locus_tag="L1V17_002406"
     tRNA            618..691
                     /locus_tag="L1V17_002406"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:652..654,aa:Pro,seq:tgg)
     gene            711..783
                     /locus_tag="L1V17_002407"
     tRNA            711..783
                     /locus_tag="L1V17_002407"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:744..746,aa:Ala,seq:tgc)
     gene            811..884
                     /locus_tag="L1V17_002408"
     tRNA            811..884
                     /locus_tag="L1V17_002408"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:845..847,aa:Met,seq:cat)
     gene            898..971
                     /locus_tag="L1V17_002409"
     tRNA            898..971
                     /locus_tag="L1V17_002409"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:932..934,aa:Ile,seq:cat)
     gene            995..1084
                     /locus_tag="L1V17_002410"
     tRNA            995..1084
                     /locus_tag="L1V17_002410"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1031..1033,aa:Ser,seq:tga)
     gene            1097..1170
                     /locus_tag="L1V17_002411"
     tRNA            1097..1170
                     /locus_tag="L1V17_002411"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1131..1133,aa:Met,seq:cat)
     gene            1189..1264
                     /locus_tag="L1V17_002412"
     tRNA            1189..1264
                     /locus_tag="L1V17_002412"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1222..1224,aa:Asp,seq:gtc)
     gene            1266..1336
                     /locus_tag="L1V17_002413"
     tRNA            1266..1336
                     /locus_tag="L1V17_002413"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1298..1300,aa:Gly,seq:tcc)
     gene            1350..1423
                     /locus_tag="L1V17_002414"
     tRNA            1350..1423
                     /locus_tag="L1V17_002414"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1384..1386,aa:Ile,seq:gat)
     gene            1448..1535
                     /locus_tag="L1V17_002415"
     tRNA            1448..1535
                     /locus_tag="L1V17_002415"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1482..1484,aa:Ser,seq:gct)
     gene            1557..1628
                     /locus_tag="L1V17_002416"
     tRNA            1557..1628
                     /locus_tag="L1V17_002416"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1590..1592,aa:Glu,seq:ttc)
     gene            1651..1740
                     /locus_tag="L1V17_002417"
     tRNA            1651..1740
                     /locus_tag="L1V17_002417"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1687..1689,aa:Ser,seq:tga)
     gene            1753..1826
                     /locus_tag="L1V17_002418"
     tRNA            1753..1826
                     /locus_tag="L1V17_002418"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1787..1789,aa:Met,seq:cat)
     gene            1845..1917
                     /locus_tag="L1V17_002419"
     tRNA            1845..1917
                     /locus_tag="L1V17_002419"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1878..1880,aa:Asp,seq:gtc)
     gene            1921..1993
                     /locus_tag="L1V17_002420"
     tRNA            1921..1993
                     /locus_tag="L1V17_002420"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1954..1956,aa:Phe,seq:gaa)
     gene            1998..2068
                     /locus_tag="L1V17_002421"
     tRNA            1998..2068
                     /locus_tag="L1V17_002421"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2030..2032,aa:Gly,seq:tcc)
     gene            2081..2154
                     /locus_tag="L1V17_002422"
     tRNA            2081..2154
                     /locus_tag="L1V17_002422"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2115..2117,aa:Ile,seq:gat)
     gene            2166..2237
                     /locus_tag="L1V17_002423"
     tRNA            2166..2237
                     /locus_tag="L1V17_002423"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2199..2201,aa:Glu,seq:ttc)
     regulatory      2426..2505
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            2503..3696
                     /locus_tag="L1V17_002424"
     CDS             2503..3696
                     /locus_tag="L1V17_002424"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBN1237137.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            3826..5298
                     /locus_tag="L1V17_002425"
     CDS             3826..5298
                     /locus_tag="L1V17_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1237138.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            5381..6169
                     /locus_tag="L1V17_002426"
     CDS             5381..6169
                     /locus_tag="L1V17_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBN1237139.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(6236..6904)
                     /locus_tag="L1V17_002427"
     CDS             complement(6236..6904)
                     /locus_tag="L1V17_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HBN1237140.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQIMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            7019..8731
                     /locus_tag="L1V17_002428"
     CDS             7019..8731
                     /locus_tag="L1V17_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1237141.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            8734..10506
                     /locus_tag="L1V17_002429"
     CDS             8734..10506
                     /locus_tag="L1V17_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1237142.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENCKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
     gene            complement(10588..>11233)
                     /locus_tag="L1V17_002430"
     CDS             complement(10588..>11233)
                     /locus_tag="L1V17_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1237143.1"
                     /translation="SLARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLI
                     TKFLFLTGLRYGELISLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNA
                     KEIIDQLIEENKLIKNNKDKYIFISKNGNPISIQAYNQSLRAVSKELNLDKKVSSHML
                     RHSHISLLTELGIPLKAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
BASE COUNT         3231 a         2011 c         2545 g         3446 t
ORIGIN      
        1 aagttatcca tggaggttta gctcagctgg gagagcatct gccttacaag cagagggtca
       61 gcggttcgat cccgttaacc tccatatgag ccgttagctc agttggtaga gcatctgact
      121 tttaatcaga gggtcacagg ttcgagccct gtacggctca tatttttgcg ggtgtggcgg
      181 aattggcaga cgcactagat ttaggatcta gcgccttacg gcgtgggggt tcaagtccct
      241 tcacccgcat aatttaagtt ttacatgccg gcttagctca gttggtagag catctgattt
      301 gtaatcagag ggtcgagggt tcaagtcctt tagccggcat ctttaaacac gcggaaatag
      361 ctcagtggta gagcaccacc ttgccaaggt gggggtcgcg ggttcgaacc ccgttttccg
      421 ctttgccaaa gcaatcgcgc cggggtggcg gaactggcag acgcacagga cttaaaatcc
      481 tgcggtgagt gatcaccgta ccggttcgat tccggtcctc ggcatttcaa atatgcgccc
      541 atagctcaac tggatagagt gtttgactac ggatcaaaag gttaggggtt cgactcctct
      601 tgggcgcgtt aattaaacgg gaagtagctc agcttggtag agcacttggt ttgggaccaa
      661 ggggtcgcag gttcgaatcc tgtcttcccg ataattataa atttaaacac ggggccttag
      721 ctcagctggg agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct
      781 ccatttcatt taaataatga atatcttttt cgcggtgtag ctcagctggc tagagcgtcc
      841 ggttcatacc cgggaggtcg ggggttcgat cccctccgcc gcgattttta agagcctgga
      901 cctttagctc agttggttag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc
      961 tacaaggtcc attgtggcgt tgtaagtttc atatggagga ttacccaagt ccggctgaag
     1021 ggaacggtct tgaaaaccgt caggcgggta aaaccgtgca agggttcgaa tcccttatcc
     1081 tcctttttca tattatcgcg ggatggagca gtctggtagc tcgtcgggct cataacccga
     1141 aggtcgtagg ttcaaatcct gctcccgcaa ttaaaaacta aaaacactgg ttccgtggtg
     1201 taggggttaa catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc
     1261 gccatgcggg tgtagtttag tggtaaaacc acagccttcc aagctgttgt cgcgagttcg
     1321 attctcgtca cccgctttta gttttttatg ggcctatagc tcagctggtt agagcgcacg
     1381 cctgataagc gtgaggtcga tggttcgagt ccatttaggc ccattagtac aaaatcttat
     1441 tggttttggg gaagtactca agtggctgaa gaggcgcccc tgctaagggt gtaggtcggg
     1501 aaaccggcgc gagggttcaa atccctcctt ctccgtttca atattttgtt ttacctggcc
     1561 cgttggtcaa gcggttaaga caccgccctt tcacggcggt aacacgggtt cgaatcccgt
     1621 acgggtcatt aatttaatat agttttacat ggaggattac ccaagtccgg ctgaagggaa
     1681 cggtcttgaa aaccgtcagg cgggtaaaac cgtgcaaggg ttcgaatccc ttatcctcct
     1741 ttttcatatt atcgcgggat ggagcagtct ggtagctcgt cgggctcata acccgaaggt
     1801 cgtaggttca aatcctgctc ccgcaattaa aaactaaaaa cattggttcc gtggtgtagg
     1861 ggttaacatg cctgcctgtc acgcaggaga tcgcgggttc gattcccgtc ggaaccgttt
     1921 ggctcggtag ctcagttggt agagcaatgg attgaagctc catgtgtcgg cagttcgatt
     1981 ctgtcccgcg ccattatgcg ggtgtagttt agtggtaaaa ccacagcctt ccaagctgtt
     2041 gtcgcgagtt cgattctcgt cacccgcttt tagtttttat gggcctatag ctcagctggt
     2101 tagagcgcac gcctgataag cgtgaggtcg atggttcgag tccatttagg cccatttatt
     2161 ttattggccc gttggtcaag cggttaagac accgcccttt cacggcggta acacgggttc
     2221 gaatcccgta cgggtcatgg aagatacttt ttgagtatct ttttcttttt atctgaaaga
     2281 atgattttaa aaagcttagc agagttatct ttatggatga ttgtgctaag cttttttgga
     2341 cagttctaat gtaaaatatt tttatatttt ttaagcaaaa aaatgaaaaa atacgagcag
     2401 aaaactgttt tatctgctat acttggttcg ttgcaagttc ccgaaaggat ccgcaggacg
     2461 gagatgcctt gtaaccgaat ttaactaggg ggaatcatta taatggtaga aagacactta
     2521 tttacatcag aatctgtttc tgaaggacat ccagataaaa ttgctgacca aatcagtgat
     2581 gcaatcttgg atgcaatttt aaaacaagat ccaacagcac gagtagcgtg tgaaacgtct
     2641 gtaacaactg gtcttgtttt agtatttgga gaaatatcta cgacggcata tgtagatatt
     2701 caaaaagtcg tacgggaaac aataaaagaa attggttata cacgtgcaaa attcggattt
     2761 gatggagata cagcagctgt attggttgcg attgatgaac aatctcctga tattgctcaa
     2821 ggagttgatg aagcacttga gatccgggat gaagataaaa aagacgtatt agatgagatt
     2881 ggtgctggtg accaaggttt aatgtttggg tttgctgtag atgaaacacc agaattgatg
     2941 cctttaccaa tcgctttgag tcatcgtctg gtacgacgct tggcagattt gcgtaaatca
     3001 aatgaattaa cgtatttacg tccagatgca aaatctcaag taacggttga atatgatgat
     3061 caaggacaac cggaacgcgt agatacaatc gttatttcaa cacagcatga tgatgcagta
     3121 gataatgaaa caattcgtca tgatgtcatc gaaaaagtag tgaaggaagt tattccagct
     3181 gaattattag atgatcaaac gaaatattat atcaatccga ctggccgatt tgtcattggt
     3241 ggtcctcaag gggatgccgg attaacagga agaaaaatca ttgttgatac gtatggcggt
     3301 tatgctcgtc atggtggcgg tgctttttct ggtaaagatg cgacaaaagt tgaccgttct
     3361 gccagctatg ctgcacgtta tattgctaaa aacattgttg cagcagggct tgctcgcaaa
     3421 gcagaagtac agctagctta tgcgattggt gttgctcaac ctgtttcgat ctcaatcaat
     3481 actttcggta ctggaacggt tccggaagaa gaactgattg ctgcagtgag agaaaacttc
     3541 gatcttcggc cagcaggaat catcgagatg cttgatttgc gtcgtccgat ttacaaacaa
     3601 acagctgctt acggtcattt tggtcgtaca gatgtagatt tgccttggga acatacggac
     3661 aaagtagatg cgttgaaagc aagtttagca aaataagtta tattcagctg gaacgatcgc
     3721 caagtggtgg ttgttccagc tttttttatg gcagttaacc tcttgaaaaa gatagtaatt
     3781 atttatctat ttttagatcc tgtcataatg aaagggagga ataagatgaa aaaagaaaca
     3841 aatgttactt tggtcacagt gagtattttc attgcaacgt tcatgacggc tattgaaggt
     3901 acaatcgtaa caaccgctat gccaacgatt gtcggttcat tacatggaat ggaaatcatg
     3961 aactgggtat tttcgattta tttgctgaca aacgctatgc ttactccgat ttacggaaaa
     4021 cttgcggata aagtgggacg gaaaccaatc tttatttttg ggacattatt gtttattatc
     4081 ggttcgttat tttgcggttt atctcaaagc atgattgggt tgattgctgc tcgtgcgatt
     4141 caagggatgg gtgctggggc aatgatgcca gtagctttga cgatcatcgg cgatctttat
     4201 tctattgaaa agcgagcaaa agttttaggt ttgaatagtt cagcctgggg gattgccagt
     4261 gtttttggac cgcttgcggg aggattcatc gttgaaacga tcagctggca ctggatcttt
     4321 tttatcaatg tgccgatcgg aattctatta attattttga tttggctata tttaaatgaa
     4381 ccaaaaatca tacatgagtc taaaccaatg gatatttttg gtagttttag tttgatggcc
     4441 atgcttgtct cattgctgtt agggttccaa ttattaggag acgaaggaat gagtccgctt
     4501 gtttctgctt tgctgctagg tagtatcgta atgttaggta tttttgtttt tgccgaaaaa
     4561 agagctaaag atcctgtcat catgatgcat ttattcaaaa atccactatt tgttgtggtc
     4621 aacttggctg cagcattggc tagtggtttt ttgatgggaa tcgatgttta tatccctatg
     4681 tggatgcaag gtgtattagg gctgaatgca gcaattggtg ggctggtatt agcaccatta
     4741 tcactagtct ggatggtcgg ttctttcctt gcaagcaagt ggatgactca aatgaaaact
     4801 cattgggtct tgagaattgg actactaatc gcagctattg ggggcgcttg gttgtatctt
     4861 atgcctttca gaagtaacta tttatggttt tttgctatat caacggtcat cggtataggc
     4921 ttaggtgtga ccatgactac ctcgactgtc agtgcacaaa atagtgtatc tcgtgaccag
     4981 cttggtgtag caacttcttt taatacgtta gttcgaacaa ttggtcaaac agtcatggtt
     5041 tctatttttg gtttattgat aaatggggta actaaacgag aacttgcagc agcaaattta
     5101 acaaatgatg cagatatcat gaataaactg gtgaatccac aaacggctaa atatattgat
     5161 gcggatattt tgttaccatt aagaaaaatt ctttatgatg ggttacattc cgtttatcta
     5221 gttggcttgt tactcgtgat cattgctttg gtcttaacgc ttttcgttca tgaaaaaagt
     5281 ggtaaaataa aacagtagtt tcggttaaga tatgtacgta gccgaatcat tcaaatttaa
     5341 agttattcaa aaataacttc ttactaagga aggcgaaaat atggcattta ttcaagcaaa
     5401 tatttattcg aatgtgttag aaatggaagt caatctaaat gtgatactac cgcaaacaac
     5461 aaaaaaggtg attggcacca gttcagagca agagacaacg gatatacctg ttttatattt
     5521 acttcatgga atgggtggca atcatagtgt atgggaaaga cgtacgtcga ttgaacgtta
     5581 tgtagcaaac tacggattag ctgtcatcat gccatctact gatcttggct ggtacacaga
     5641 tacagtttat gacatgaagt attggacatt cattgcagaa gagctacctg agatttgtca
     5701 tgaattattc ccgcaattaa caagaaaaag agaaaaaaca tatgccgctg gattatcgat
     5761 gggcggatat ggcgcgttaa aactaggcct tgcaaaatca gaaaatttcg cagcagtaat
     5821 ctctctttca ggcgctgttt ctgtaggaaa tcgaatggat gatcttttga tggttcgtaa
     5881 agcatctttt tgggaaggga tctttggacc attggatcaa atcgaaggtt caaaaaatga
     5941 tccgcaatac ttattgaaag aactagtaaa aagcggaaaa ccagttccaa gattttatat
     6001 ggcttgtggg gaatctgatt ttctttatca ggcaaatcag gaaatggtat ctgctatgca
     6061 ggaacaaggc ttggcggtca cctttgaaca aggacctggc gatcataact ggatcttctg
     6121 ggaccaatgg attcaacgtg cattggcgtg gctaatggaa gaaaaataaa aaaagagtct
     6181 taaaaagata gctcctatag agatcacaaa catagtgatc tctataggag cttttttact
     6241 gctcgttttc tcttctttta ttttgttggc ataagccttc aatataggtt tgtgcactcg
     6301 ttagaaagag tgctttttca ttcaattctg catgggactg catactttct ttaaatccct
     6361 ctaattgatt ttcaactaca taattacgca taaatagaac tgtttctttc aaaaattcat
     6421 ttccgtccat aattttttgt cgaagctgct gttcatgctg ctgatccatt aactgtccaa
     6481 tcaataaatt gtggagagag gcaatggcct gatgactttg ggtgactgaa aatccttcac
     6541 gaacaagtaa ttggatcatt tgctccaaat gttctaatcg actcggaaaa gcgggcacag
     6601 tattgatttc taattctgcc ccacaaggga aacgtgtata aaggtcatag taattttcca
     6661 tatactgcag caactgttca ttccaaggca aagttggatc tggaagcgct aattcttctt
     6721 ccattgtttc agccattatt tgcaagagct gttgtttgtt tttgaaatac caatataaag
     6781 caggtgcttg aacatgaatt ctgtttgcga tgtttcgcat ggaaagctgc gaaagagctt
     6841 gtgtttcagc caggatatca aaggcggcct gaatgatgat tgcttgagaa agctttattt
     6901 ccattttatc aacctcgtgt attgcattat ctttttaaac atggtaaatt gttagtcggt
     6961 ctaattttac agtgttaaat tagtcctgtc aatttaaaca aaggggtgta atcaacgaat
     7021 gaaattaatc ttacgacatg cgaaaaaata taaagtagct gtttttattt ccttgctgtc
     7081 cgtagcagtc atggttgcag cagcattatg gcaacctaag ttactacagc aagtattgga
     7141 agctattatt acagaagata atgatgaaat gaaaacaatt ggtatttacc tgatcagtct
     7201 ggctttgcta ggattagccg caggtgtaac gaacacgatt ttctctgcaa aagtagctca
     7261 aggcgtaagt gcagatatcc gagaagaagc atttcgaaag atccagacat tttcatttgg
     7321 aaatatcgaa cagttctctg ctggaaatct tgttgttcgt ctaacaaatg atatcacgca
     7381 aatccaaaat ttagtgatga tttctttgca atcacttttt cgaattccat tcttatttat
     7441 tggtgccttc attttagcta tgatcacgat gccgcaatta tggtggatca tcgtagcgct
     7501 tatcgttacg gtatttctga ttacggcact ttcatttaca aggatgggca agcacttcat
     7561 gatcattcaa aaactgattg atcgtgtgaa tagcattgca aaagaaaact tactagggat
     7621 tcgtgtagtg aaatcttttg tacaagaaga aaaccaattg aagtcattca gcaaagtaag
     7681 tgaggactta acaaaacaca acatcatagt cggtacatta ttttctgtga tgatcccgtc
     7741 cttcatgctg gctgccaatt tggctgtggt tggggcgatc ttttttgtga gcgatcttgt
     7801 taaagatgat cctacgttaa ttggtggaat tgcttcattc atgaactact tgatgcagat
     7861 tatgatggca atcattattg gcggaatgat gatgatgatg acttcaagag cagccgtatc
     7921 gctgaagcgg attgcggaaa ttttagatgc tgaaccagat cttacttatt tagacgttcc
     7981 agaacaagag ttgacgggtt ctgtcacttt tgaccatgtt tcttttcgtt atcctggtga
     8041 ggatacagat acgcttaaag atatcagctt ttctatcaaa cctggagaaa tggttggtat
     8101 cgtcggggcg actggtgccg ggaagtcaac actagcacaa ttgatccctc gtctatttga
     8161 tccgacagaa ggcaaagttg aagtaggtgg tgtagatctt cgtcaagtaa atgaaaagag
     8221 tttaagacaa acggtttcct ttgttttgca aaaagcaatt ttattctcag gaacgattgc
     8281 tcaaaacttg cgccaaggga aaaagaatgc aacagaaaaa gagatggaac atgcttcttc
     8341 tattgctcaa gcaaaagaat tcatcgaaaa gttatctgat cgttacgaag caccaataga
     8401 agaacgtagc agtaactttt ctggtggtca aaagcaacgt ttatccatta ctcgtggcgt
     8461 tatcggtaat ccaaagatct tgatcctaga tgacagtacg agtgcactgg atgctcgctc
     8521 tgaaaagctg gtccgagaag cactcgatcg agatttgaag ggaacaacga cgattgtcat
     8581 cgcacaaaaa attgcttctg ttgtcaaagc agaccgcatc ttagtattgg atgaaggcag
     8641 attagtcggc gaaggaaccc atgaggaatt ggtagctgga aaccgtgtct atcaggaaat
     8701 ctttgaaact caaaaaggaa cggaggagta agtatgactg atctaataaa agcaagtaaa
     8761 tttttctatc actatttgaa gcggtacaaa ctctcctttt tctttatctt tatcacagtg
     8821 atcattgcta cctatctaca agtaaaggca cctcaataca tcggggaagc ttttcaagaa
     8881 ttagctaatt acgtaggagg cttgatgcaa ggcgtagacg ataaaagcaa atttgtttct
     8941 gtaatatgga aactcttgct gttttatgta ctagctagtg cagccaactt tatctatagt
     9001 attttgttca cacaagtagt agggaagtca acgaaccgaa tgcgtatcgg tctattcaac
     9061 aaattggaaa aattgacgat ccgtttcttt gattctcatc aagacggtga aattttaagt
     9121 cgttttacca gtgacttaga taatattcaa aatagtttga accaagcttt gcttcaagtc
     9181 atcacgaatg ctgttttact tgtcgggatc ttgatcatga tgttccgcca aaatgtagag
     9241 ttagcttggg ctacaattgc ttccactcca gtagccgttt tgatagctgt cttgattatc
     9301 cgcaaagcac ggaaatatgt ggatcttcag caagatgaag tggggaaact aaatggttat
     9361 atggatgaaa aaatcagcgg acaacgtgtc atcatcacaa atggcttaca agaagaaacg
     9421 attgaaggat tcttagagca taatcaaagt gttcgcgaag caaccttcaa aggacaagct
     9481 tattctggtc tactatttcc gatgatgcaa ggaatgtcac tggtcaatac agcgatagtt
     9541 atctttttcg gcggctggtt agcattaaat ggtgatttgg aacgttcggt ggcattaggc
     9601 ttagttgtga cattcgtcca gtattcacaa caatattacc aaccactgat gcagatttca
     9661 tctggataca gcatgatcca attagcgatt acaggggcaa gacgattgaa tgaaatattt
     9721 gatgaaaaag atgaagtcaa accagaaaac tgtaaagcat ttgatggtgt tgaaaaaggt
     9781 cttgcgttgc agcacgtaga ttttggttat tctccagaaa aactagtctt gaaagatgtc
     9841 tcgatcaatg tggacaaagg agaaatggtt gctcttgttg gtccaacagg atcggggaaa
     9901 acgacgatca tgaatctgct aaaccgtttt tacgatgtca atgatggttc agtagtcatc
     9961 gatggaatag atatccgaga ttatgatctt gatgcattac gtagacatgt aggaatcgtt
    10021 ttgcaagaat ctgtattgtt ctccggaacg atcaaagaca atatcacatt cggcaaaccg
    10081 gacgcttcag atgaagaagt catcaatgca gcaaaacaag cgaatattca tgacttcatc
    10141 atgacgttag aaaaaggtta tgatacagag atatccgaag aaaataactt attcagtaca
    10201 ggtcaaaagc agttgatcag tattgctcga acgatcatca caaatccatc tttattgatt
    10261 ttggatgaag caacaagtaa tgtagacacg gtaacagaag caaggatcca aaaagcaatg
    10321 gatgaagcaa tcaaaggaag aaccagcttt gtgattgctc accggctgaa aacaatcttg
    10381 aatgcagata gaatcgttgt cttgcgtgat ggggaagtca ttgaagaagg cagtcatcac
    10441 gagttattag cagaaaatgg attttatgcg gaactttatc ataatcaatt tgtatttgaa
    10501 agttaaatta aaagaacctc gttataacgg ggttcttttt atatatttta tgttgtttgt
    10561 ttttataagg ggcagaaaag gggcaattta aatttctatt tttcctagtt tttctactag
    10621 ttgattttgc atatttttag ttgtatgagt ataaatcttt aatgttgttt ttgaatcttc
    10681 atgtcctaca cgatccataa tggcttttaa tgggattcct aattctgtaa gtagagaaat
    10741 gtgggaatgc cttaacatgt gagaagaaac ttttttatct aggtttaatt ctttggatac
    10801 tgctcttaaa gattgattat atgcttgaat agatatcggg ttaccatttt tagagatgaa
    10861 aatgtattta tctttattat tcttaattaa tttgttttct tcaattaatt gatctatgat
    10921 ttctttagca ttacttgata attcaatggt tctataagaa cctgtatttt tagttgttgt
    10981 tttaattttt aactcgtaat cataagtacc agaaaccgta attttattac catcataatc
    11041 agattcagtc aaagatatca attcaccata acgtagtcca gttaaaaaca aaaatttagt
    11101 aattaaagaa taacgtgact gttgatgtga acttttttgt ttactagcaa tcatttgaac
    11161 ttcttctttt gataaataac catctttttc tttttttatt tcttcgtttg tcttaggttt
    11221 tcttgctaaa gaa
//
LOCUS       DAFLWC010000093        10977 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.095, whole genome shotgun sequence.
ACCESSION   DAFLWC010000093 DAFLWC010000000
VERSION     DAFLWC010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10977
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.095"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            101..1732
                     /locus_tag="L1V17_002431"
     CDS             101..1732
                     /locus_tag="L1V17_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBN1237144.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            1735..2814
                     /gene="uxuA"
                     /locus_tag="L1V17_002432"
     CDS             1735..2814
                     /gene="uxuA"
                     /locus_tag="L1V17_002432"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBN1237145.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            2888..4315
                     /gene="uxaC"
                     /locus_tag="L1V17_002433"
     CDS             2888..4315
                     /gene="uxaC"
                     /locus_tag="L1V17_002433"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBN1237146.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            4399..5046
                     /locus_tag="L1V17_002434"
     CDS             4399..5046
                     /locus_tag="L1V17_002434"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HBN1237147.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            5166..6542
                     /locus_tag="L1V17_002435"
     CDS             5166..6542
                     /locus_tag="L1V17_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1237148.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKASNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANVQTGDVLEKLYNASTLIPSICFLIVGLILFFLYPLSKDKVLENC
                     ELLKQKHK"
     gene            6552..7346
                     /locus_tag="L1V17_002436"
     CDS             6552..7346
                     /locus_tag="L1V17_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBN1237149.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            7359..9125
                     /locus_tag="L1V17_002437"
     CDS             7359..9125
                     /locus_tag="L1V17_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HBN1237150.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            9148..10956
                     /gene="uidA"
                     /locus_tag="L1V17_002438"
     CDS             9148..10956
                     /gene="uidA"
                     /locus_tag="L1V17_002438"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HBN1237151.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
BASE COUNT         3847 a         1409 c         2245 g         3476 t
ORIGIN      
        1 aaaaagcaag tttattccct ttttatattg acaacggtta caatgggttt taaaatataa
       61 aatgtatcaa aactaacata tcagtttgag gaggttaatt atggtttcga ttaaaaattg
      121 gcaaaattct atcgaagaat tcaatgaaat gcagattcta ctgccgtgtt ttgatgtcaa
      181 agaagttaag caagaaggcc agcaacatcc agtatggctt cattttggtg gaggaaatct
      241 ttatcgagga tttcatgcag aaattgctca atgcttagca gatcaaaatg aattagaaac
      301 aggagtagtt gtgtgtgaaa catttgatga agaagtagtg gaaaaagctt atcatgacta
      361 taacaatgac attttggaaa ttgttatgag tggagatggt gaactcaaaa aaagactttt
      421 ggcagtaacg gctgatagtt tatattgcaa tccgaagaat atagcggact atcaaagagt
      481 ggttaaatat tttgaagatc ctaaattaca gtttacaacg tttactatta ctgaaaaagg
      541 ttacagttta aaagattcta aagggcaatt cttttcggta gtcaaagctg atatcaaatc
      601 tggacctagc aatcctcaac atacgatgag tattgtaaca tccttgttat atagcagatt
      661 taatgctgga gagttgccga ttgcgatggt ttctactgat aatttctcac agaatggtca
      721 acgttttcaa gatagtattt ttacgattgc agaagcttgg caaaaagaag gatatgtttc
      781 tgaaaaattt attgcttatt taaaggataa agaaaaagtg acttttcctt ggagtatgat
      841 tgatcgaatt acgccaaatc cttcagagaa tgtaaaggaa gatctattga tgatggggct
      901 cgaggattta gatatcattc acacaaaaaa acataccaat attgctgctt tcactaatac
      961 tgaggtagtt cattatttag ttattgaaga tagttttcca aatggccggc ctaaattgga
     1021 aaaggctggt gtgattatga cagatagaga gacggttgat aaagcagaca tcatgaaggt
     1081 tacgacaagc ttgaatccac ttcatactgc tttggcagta acaggttgtc tgctaggata
     1141 tcaatcaatt tcagcagaga tgcaggatga tgatttggtt ggtttaatca aaggaatagg
     1201 ttatttagaa ggtttaccag tagttgaaaa tccaggcatt attgatccaa aacaatttat
     1261 tgatgaagta attaataaac gtttgcctaa tccctatatt ccagatacac cacaacgaat
     1321 tgcaacagat acttctcaaa aagtagcgat tcgctatggt gaaacaatta aaaagtatgt
     1381 cgaaaaagac ggaaatgcag aaaatctaac atttattcct atcgctattg ctgcttggtt
     1441 acgttattta ctggcagtcg atgatcaagg ggaaaatttt gtgccaagtc ctgatccgtt
     1501 attggtagag ttgcaggata aattatcagt attgaaatta ggtgaacaag atccttcaaa
     1561 gattcattgt gcggtacagg aaattttaga aaataaagaa atctttggtt tagatttata
     1621 tcaagttggg gtaggaaaga aaactgaaaa aatcttttgc gaaatgctag taggtcctca
     1681 agcagttcgt aaaacaatca ataaatatat aacagaagtt ggaggaaagt aactatggaa
     1741 atgactttta gatggtatgg ggcaaatgaa gaaaaaatct cactacaaga aattcgtcag
     1801 atcccagcaa tgaaaggaat tgttggaaca ttaatggata taccagccgg agaggtttgg
     1861 ccgagagaac gaattaaatc tttaaaagat gaagtcgaag ccaatggact taccttgaaa
     1921 gttattgaga gtgttaatgt tcatgatgat atcaaaattg gtttaccaac acgagatcaa
     1981 tacattgaga attataaaca gacgattcgc aatttggcag aatttgggat tgaggttatc
     2041 tgttataatt ttatgccagt atttgattgg gtaaaatcgg atttggatta tcgtttagat
     2101 gatgggtctt ctacgttagc ctatatttca aaaaatatcc ctactgatcc ggaggaaatt
     2161 attagagaag tagaaaattc tactaataat tttgaattgc cgggttggga acctcatcgg
     2221 ttatcacaaa ttaagcaatt attagaagcc tataaagaag ttgatgaaga gaaattacga
     2281 gagaactttg catattttct caaagcaatt atcccgacat gtgaagaagt tgggattaaa
     2341 atggcagttc acccagatga tccaccatat tccattttcg gattacctcg tattgttaaa
     2401 aatcgtgacg atttagattg gttgtgtaat gtagtggatt ctccttctaa tggtattaca
     2461 ttatgtactg gaagtattgc agaacgacca gataatgatg tctatgaaat tctatctgaa
     2521 ttttgtcaac gggatcggat tccttttgca catgttcgta atatcaaata tttaagtgac
     2581 aatggactcg atttttacga agcgccgcat aaatcagaat atggttctct agatatgtat
     2641 aagatattaa aaacaatgta cgataatgga tttaatggct atattcgtcc agatcatggt
     2701 cggatgattt ggggagaaac cggtagacct ggttatggat tatatgaccg agctctaggt
     2761 gcagtttatt taaatggtat ttgggaagcg cttgaaaagg gggcgagtaa ataattatat
     2821 aagggagttt atttagagga aaaattttct cttctaaaaa ctaacggaag gaaaggagtg
     2881 tttaaatatg tttttagata agaacttttt attagagaat gaaatagcta aaagactttt
     2941 tcataaattt gcaaaacacc aaccaattat cgactatcat tgtcatttag acccagcata
     3001 tttgctagaa aataagcaat acaagaattt gactcaggta tggttaaatg ataaaggagc
     3061 tggagatcat tataaatggc gattgatgcg agctaatggt atagaagaag agttgatcag
     3121 tggtccaggt gatgattatg aaaaattttt agcttttgta aaaacagtgg agaaggcgcc
     3181 aggtaatcct atttttgaat ggtctcattt ggaattacaa cgttactttg atattgattt
     3241 gacaatttct gagaagaatg caccagaaat ttggcgacgt gctaacgaaa aaattcaaac
     3301 ggattcctat cgcccgaaag aattgttgga gatgatggat gtgaaagcca tctgtacaac
     3361 ggatgatcct acagatgact tgtggtatca tactgagctt tctaaacagg ataattcttt
     3421 caaggtatta cctactttcc gtccagataa ggtctggagt atcaaatcat caggcttttc
     3481 gaactatatt ttaaaactta gtcaaacagc ggctatacca atcaaagact ttaatgggtt
     3541 gaagcaagca ttgagccaac gagtggatca ttttcatcaa attggctgtc gattagcaga
     3601 tcacggtttg aatacttatt tttatgaaat agcagatgaa aaaatactcg acaatctgtt
     3661 aataaaagct ttagcaggaa aaacggattt ccatttatca gaaattgcac aatttgttac
     3721 aggtattcaa ttacatttga tgtctgagta tacaagatat ggttggacga tgcaaatgca
     3781 tttaaatgct ttaagaaata attcaagtat attaaaggaa caaattggag tagatgtcgg
     3841 tggtgattcg atgggggatc aagctagttt gacacaaaat gttgtagcat tgttcgatac
     3901 cgctgaaaag agtgggtgct taccaaaaac aattttatat tcattaaatc caactgattg
     3961 gcttccacta gcaacagcaa tgcaaagctt ccaagggggt atgattcaaa aaatccaatt
     4021 gggatgtgct tggtggttca atgatacagc tgaaggaatg cgtcaacagt tgactacgat
     4081 ggcacaacaa agtttgttgt cgaattttac aggtatgttg actgattctc gaagttttct
     4141 aagctatcct cgccatgagt attttcgtcg agtattatgt caattactaa gcgagtgggt
     4201 taaagcaggc cgaattccag atgatgaaat gtatcttagt cagatagtgg agaatatttg
     4261 ttatcgtaat gcgtataatt attttaattt ttttgaaatc ggaagtagaa aataatactt
     4321 gaaataaaag cttaaattta ttctttgtaa gttagtacag ctagacaaag tatgtatcca
     4381 taaaggaagg agatagatat gaaaaaagta gaaattttaa gtaagttaga agcggctgga
     4441 gtcattgcgg ttgtacgtgg gaaaaataag gatgaggcca ttaaagcaat aaattcaatt
     4501 attgcgggtg gaattaaagg gattgaacta acttttacag ttcctaatgc tgaagaaata
     4561 atcaaagaaa ttgctaaaaa atatgctgat caaaaagatg taataatcgg agccggtacg
     4621 gttttagatg cgtttactgc tcgtatcgca attatggctg gggcagaata tatcgttagt
     4681 ccatcttttg atcgacaaac agctgagatt tgtaatttat atcaaattcc ttatttacca
     4741 ggttgtatga caattactga gataaaggag gcacttactg ctggcgtaga tatcattaaa
     4801 ctattcccag gttctgcttt tggtccatcc attgtaaaag cctatcaagc tccattacca
     4861 cacgtaaata taatgcctac tggcggagta agtatagaga acttagaaga ttggtttgaa
     4921 gtaggagttg ttgcagttgg tgtaggtggg aatttattgg cttctgttga aaaaggtgat
     4981 tttgaagaag taagtcgagt agctagtaaa tatatagata agttttatga gataaagaat
     5041 tattaggaga aaaaacaaat aatactctga aatgtaaaaa ataaatactg actctttacg
     5101 cttcagagta tagtacgtac tttcatcaga atgaaaacgc ttaacaacag aagggagaga
     5161 attgtatgga aagaaaattt ggtataagag acaaaatagg atatatgttt ggagattttg
     5221 gaaacgattt tactttcatt tttgctagtt cttttttaat gatcttttat acaaaagtat
     5281 tggggataag cggagctgcc gttggaacat tatttttagt agcaagattt atcgatgcag
     5341 ttactgatgt aactatgggg cgtattgttg atagatcgaa agcaactaag cagggtaagt
     5401 ttaaaccgtg gattttaaga atgagtggtc cagtcgcttt agcaagtttt ttaatgtatc
     5461 aaacttctat gatttcagct tctatgagcg ttaaggtagt atacatgtat gttacgtata
     5521 tattatgggg gagtattttt tacacatcta taaatattcc ttatggatca atggcatcag
     5581 ctattacttc tattacagaa gaaagaacaa tgctatcgac attccgaaat gttggagcta
     5641 ctttagcaag tttggtcatt ggtgtattaa caccattatt tatttataca agagatgatt
     5701 caggcgctca aatagttcgt ggtggatcaa cttttacaat tgttgcggga atattttcga
     5761 tatgtgcact tatttgttat ttaatatgtt ataaactaac tactgaacga gtaagaattg
     5821 accaatctca atacaaagtt tcattgttaa aatctttaaa agggttagtt aaaaataggg
     5881 cattactttc tataattggt gcggctattt tcttactcct tgctcaatta ttaattatga
     5941 gtatgaataa ttatgtattt cctgattact ataatgatgc acagggaata gttttaatga
     6001 attttatcaa tcctattttg gttttaatag ttgtttcgcc tttaactttg tttttaagta
     6061 aaaaatatgg aaaaaaagaa ctggcatcag taggaatgtt cttttcagca atagtatatt
     6121 tgatcttatt tttgataaaa gctagtaata tgtatgtatt cttaattctt agttcggttg
     6181 gctatatggg tttgggtgtg tttaatactg ttatttgggc aaatattact gatgttattg
     6241 atgatcaaga agtaaagtct gatcaaagag aagatgggac cgtatatgcg gtatattctt
     6301 ttgctagaaa aataggtcaa gctctagctg gaggcgtcgg aggttggact ctttctatta
     6361 taggctatga ctctttagca aatgtacaaa cgggagatgt tttagaaaag ttatataacg
     6421 cttcaacatt aattccatca atttgttttc tgattgtagg attaatttta tttttccttt
     6481 atccattatc taaagataaa gtcttagaaa attgcgagct tttaaaacaa aaacataaat
     6541 aggagagaaa tatgaataat tggatatttt gtattgattc agatggctgt gttatggata
     6601 cgatgactta taaacacaat ctctttttcg gaccaattgc tgcagagatt tttgatgttc
     6661 atcatagaga aaaattccta caggattgga ataatattaa tttatattca gagactcgtg
     6721 gaataaacag atttttaggt ttagttaaaa cattagaaaa aaatgatgta acatcgatta
     6781 atcgattaaa gcactgggta tctctaacaa aagaattgtc taatccatct ttgaagaggg
     6841 aaatagaata ttctcagtca gaggatttat taaaagcttt aaaatggtcg gaagaagtca
     6901 atcaacagat tagtcaagca aaaggattag ataaaccctt tttaagtgct agagatacta
     6961 taaaagctct gaaaaaatat gggaagataa ttattgtaag ctcagctaat aaggaagctg
     7021 ttcaagaaga atgggaaaga catgaattat tatcattagt tgatgaactg tgttgtcaag
     7081 ataaaggaaa aaaagaagat attattcgaa gtgtaattga aaatggttgt gatttggata
     7141 agatattaat gattggtgat tctcctggtg atctagaagc tgcaaataaa aataaagttt
     7201 tcttttatcc tattttggtc aataaagaaa aagaatcatg ggaaaactta agaactgatg
     7261 ttttatttaa atgtttatcg ggagattatg tagatattga acaaaaatat atagatactt
     7321 tttggaaaaa tcttactaat aagtagagga gaaagaaaat gactataaaa gtagatttac
     7381 gaaaaaaacc atataattta gatgaagatg ctatttcttg gattgaagag acgattgatt
     7441 ctatgacttt ggaagaaaaa ataggtcaat tgtttgttaa tatgggatct agtcgtgata
     7501 aaaattactt gagtaatatg gtcaatcagt accatattgg agctgtacga tataatccag
     7561 gaactgctga tgaggtatat gatcaaaact atatcttaca aacagaaagt aaaattcctc
     7621 tattaattgc tgctaatacg gaagcaggtg gtaacggagc ttgtacagat ggtactgaag
     7681 ttggtgtaga agtaaaaatt ggtgcaacaa atgatgcgaa atatgcttat gaattaggga
     7741 gagtttctgg gattgaagca tcggctattg gatgtaactg gagttttgct cctattgtag
     7801 atattaatag aaattggaga aatcctatca tttctagtcg atcttttgga caaaaccctg
     7861 ataaagtttt agaacttagt ttagcttata tgaaaggtat tcaggagagt ggaattttgc
     7921 ctgcagctaa acatttccct ggtgacggta ttgacgaacg agatcagcat ctatctttta
     7981 gtattaatag tttaggtacg gaagaatggg ataattcttt tggaaaagta tactcaggct
     8041 taatagaagc tggattacct tcaattatgg caggtcatat ccatatgcca gcttattcaa
     8101 aacattttaa tcctgatctg aaagatgaag atttacttcc tgcaacttta tcaaaagaat
     8161 taatcactga cttacttaga ggaaaactcg gatttaatgg attagtagtt actgatgcta
     8221 gtcatatgtt aggaatgact ggggcaatga aacgatcaga attattgccc acttctattg
     8281 cagctggatg tgatctattt ctatttttta atgatccaga tgaagacttt aattatatga
     8341 tggaaggcta tcgtaaagga attatcactg atgatcggtt attagatgcc ttaaaaagaa
     8401 ttttagggtt aaaagctaaa ttgggattac acaaaaaagc aaaagaacaa attttattac
     8461 ctaagcaaga agctctggaa aaaattggtt taattgaaaa taaatcaatt tttaaagagg
     8521 tggctgacca agcaattaca ttagttaaag ataaacaaga tatttggcct attgtaccag
     8581 aaaaatataa aaggatttta ctagtagatg tacatggggt aaaaggtggg tttggtgaag
     8641 tagttgctgg aaatagacct caagccattg atttattgaa acagattttg tcagcaaaag
     8701 gatttgaagt tgaaaaatac atttcacctg aagaagaatt gaaaggatta tcgcaagaag
     8761 aaaaaattaa aaatatagct ggaatatatg ctgctaagag accaattaaa aatttaacta
     8821 aaaaatatga cttgatcatt aatatagcta atgttaatcc aggcacagtt caacgaattg
     8881 tctggccagc aagtaaagga actccggata taccgtttta cattcatgaa attccaacaa
     8941 tttttgtatc tgtacagtgt ccgtttcatt tggctgatgt acctcaagta aagacttata
     9001 ttaatactta tgatggaaaa caagaaactt tagaaatatt ggtggacaaa ctaatgggtc
     9061 tttctgaatt taagggagta agtccaatag atgcttattg tggtttaaag gatacattta
     9121 tttaatattt agataggagt ggtttatatg ttgtatccca ttatgacaga gacgaggcaa
     9181 gtaattgact taagcggtct ctggagattt aaattagata caaatgatga cttacaggaa
     9241 gaacttgctt tagaaccaat aaatgaaaaa gagagttatc cgatttcagt tccctcttct
     9301 tataatgatt tatttgaaac agagaacatt agaaatcatg ttggatgggt gtggtatgaa
     9361 aaagaagtga ctcttcctaa aagattatta gaagaaagat tagttcttcg ttttggatct
     9421 gcaacacatg aagcaaaagt ttttttgaat ggaaagttta ttactcaaca caaaggtggg
     9481 tttacaccat ttgagtctga aattaatcgg tttgtaaaag acgggaataa tcgaattaca
     9541 gttgctgtaa acaatattat tgacgatagt actttacctg tggggattat gaaggaaaca
     9601 gtacaggaaa atggggatat aaaaaaggaa aacttagtta attttgattt cttcaattat
     9661 gcaggtattc atagacctgt taagttatat acaactccga aagactatat aagtgatatt
     9721 actattaata caagaataac tgatttggat gcaagtgtag aattcaatat cgatacagaa
     9781 tggaccggaa aaatcttaat agcgatatat gacgaagagg ctcaacttgt agctgaagct
     9841 gaaggaaaga aaggaatgat tcagcttaag aatccaattt tttgggaacc tctagacgct
     9901 tatttatata gtatgaaaat tagtttaatt gatgataata aagtgatcga tacctataca
     9961 gaagaatttg gtattcgcag tgttcaggtt accaatggca aatttttgat taataataaa
    10021 cctttttatt ttaaaggatt tggtaagcat gaggattcgt atgttaatgg acgtggtttg
    10081 aatgaggctg taaatattaa agattttaat ttaatgaaat ggataggtgc taattctttt
    10141 agaacatcac attatcctta ctcagaagaa attatgcgat tagcagatcg agaaggtatt
    10201 gtagttattg atgaagtacc tgcagtaggg ttacatttaa atttcatggc cactttatta
    10261 gatgataatg tggaaaaaca taatacgtgg aaagagatac gaacagaaaa ttctcataaa
    10321 acggtgatca aggaattgat agaacgcgac aagaaccacc caagtgttgt aatgtggtct
    10381 attgcaaatg aaccagattc ggattccgaa ggtgctaaag aatattttga acctttagtt
    10441 gaattaacta aagaacttga tccgcagaaa agacctgtaa caatcgttac ttatctaaaa
    10501 tcaacgccag atgtttgtaa ggtaggagat attgtcgatg ttttatgttt aaatcgttat
    10561 tatggttggt atgtttcggg aggggatctg gcacatgcaa aatatctgtt gaaaaaagag
    10621 ctagatggat ggatggaaag atgtcctgat acgccaataa tgtttacaga atatggagca
    10681 gatacagtag ctggatttca tgatacagta ccaacaatgt ttacagaaga gtatcaagtg
    10741 gcttattacg aagcaaatca cgaagtaata gatacatgtg aaaattttgt tggtgaacaa
    10801 gtgtggaatt ttgcagattt tgcaacaagt caagggattt taagagtgca aggaaataag
    10861 aaaggaatct ttactagaga tagaaaacct aaaatgattg cttactatct acagaaacga
    10921 tggtcatcaa tacccaattt cagttataaa aaataatttg gattttttaa gaatgtt
//
LOCUS       DAFLWC010000094        10613 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.096, whole genome shotgun sequence.
ACCESSION   DAFLWC010000094 DAFLWC010000000
VERSION     DAFLWC010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10613
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.096"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            33..656
                     /locus_tag="L1V17_002439"
     CDS             33..656
                     /locus_tag="L1V17_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237152.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1106..2155
                     /locus_tag="L1V17_002440"
     CDS             1106..2155
                     /locus_tag="L1V17_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1237153.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2152..3033
                     /locus_tag="L1V17_002441"
     CDS             2152..3033
                     /locus_tag="L1V17_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1237154.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3036..3806
                     /locus_tag="L1V17_002442"
     CDS             3036..3806
                     /locus_tag="L1V17_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1237155.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4085..4939
                     /gene="aroE"
                     /locus_tag="L1V17_002443"
     CDS             4085..4939
                     /gene="aroE"
                     /locus_tag="L1V17_002443"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBN1237156.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5117..6280
                     /locus_tag="L1V17_002444"
     CDS             5117..6280
                     /locus_tag="L1V17_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBN1237157.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6397..6807
                     /locus_tag="L1V17_002445"
     CDS             6397..6807
                     /locus_tag="L1V17_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBN1237158.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6981..9209
                     /gene="topB"
                     /locus_tag="L1V17_002446"
     CDS             6981..9209
                     /gene="topB"
                     /locus_tag="L1V17_002446"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBN1237159.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9380..9664
                     /locus_tag="L1V17_002447"
     CDS             9380..9664
                     /locus_tag="L1V17_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237160.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9824..10060
                     /locus_tag="L1V17_002448"
     CDS             9824..10060
                     /locus_tag="L1V17_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBN1237161.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10057..10455
                     /locus_tag="L1V17_002449"
     CDS             10057..10455
                     /locus_tag="L1V17_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBN1237162.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
BASE COUNT         3711 a         1771 c         2241 g         2890 t
ORIGIN      
        1 aataaaaaat aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat
       61 cgagagtaca agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt
      121 attttcgacg tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt
      181 tattgccgga aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa
      241 ccagcaaatt gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg
      301 cgatatcggt gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt
      361 ttaatgatcc tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt
      421 atgatgtaca tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt
      481 tctttgatgg aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt
      541 ttgataagga gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag
      601 aagaagaatt ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca
      661 ttggcgcgat gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg
      721 tttgatcttc aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt
      781 cgattagact taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt
      841 atttcagcag aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg
      901 agactttccc atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga
      961 catgaacatt gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga
     1021 ccgctttggc cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa
     1081 agattgactt tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat
     1141 tattttagtt tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag
     1201 tacttcgacg aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca
     1261 tccggcatta gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa
     1321 agaaggagaa aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc
     1381 cacaatgagt caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc
     1441 tgccgctcaa tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac
     1501 ggatcctgtg ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg
     1561 tgtttctgat cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa
     1621 tgcaaaaaaa gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc
     1681 acaagcagaa gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc
     1741 cactaatgag attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt
     1801 tccattagat aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc
     1861 aaatatcccc gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat
     1921 cgggatcaat caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag
     1981 tggaaaagaa aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat
     2041 caatcaatct caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc
     2101 caaaatcatt acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta
     2161 tcagctattt cacaaggcat gctttgggca atattaggat tagggatttt catgacttat
     2221 cggatcttag actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc
     2281 tgtgtgacag ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt
     2341 gctggcatga tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt
     2401 attttagcag ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga
     2461 acaccaaatc tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg
     2521 ttacctgatt actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct
     2581 gtactgctat tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac
     2641 gaaacgatgg ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact
     2701 ttgtcgaacg gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca
     2761 gatgtaaata aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa
     2821 gtgatcttcc aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc
     2881 atttatcagc tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag
     2941 ttgttctccg ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg
     3001 aacttaaaaa cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa
     3061 atggcagaaa agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta
     3121 accttacaat cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa
     3181 gcacactgtt caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta
     3241 aagatcagct gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt
     3301 tccaagaccc caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg
     3361 cacaaaaaag aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag
     3421 attttttcag actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag
     3481 cgggtgaatt atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag
     3541 ctcctgagtt actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag
     3601 cattaatgcg attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca
     3661 cgcatcgaat ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga
     3721 aaatcgttca agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc
     3781 agttctttga agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact
     3841 tgaaaactca ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa
     3901 catatttggg tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt
     3961 ctttgctctg acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc
     4021 gtactttttc gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa
     4081 taagatgatt tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag
     4141 tttatcccca ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt
     4201 agctttccaa gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga
     4261 tatgttaggt gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga
     4321 ggtaagccag gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg
     4381 tttgattggc tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat
     4441 ttcgatcaaa aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac
     4501 tgttcaagct gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac
     4561 attcgctcaa gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa
     4621 agttcgtgac tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct
     4681 agtcaatgca acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat
     4741 aagcatgatg catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg
     4801 tttattaaaa gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat
     4861 ctaccaagga gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat
     4921 tgaaaagctg tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg
     4981 gtctcaagaa aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat
     5041 tatcaaaaaa tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa
     5101 acgaggagga accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa
     5161 acctctgaag cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat
     5221 ggaaaatgag gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt
     5281 gaaccaatac gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa
     5341 taaaaaattt ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc
     5401 gtggaaaaaa atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt
     5461 ttttattggt aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac
     5521 ctttcatggg caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac
     5581 acgcggagaa gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc
     5641 ccataagccg aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg
     5701 acaaaataag atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt
     5761 agtagaaaat tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga
     5821 aaaagtgatc gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa
     5881 tctggatggt gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca
     5941 gtacgcacgt ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca
     6001 agtaatgaac gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta
     6061 tgcagctggt aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa
     6121 aaacctcttt tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga
     6181 cggttcgtgg aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca
     6241 aatgaatcaa tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag
     6301 aagctgcgca aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc
     6361 ttatggtaga tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa
     6421 aatgagtcgc gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt
     6481 atcaccacat acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa
     6541 aatctaatca cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg
     6601 ccagaaggaa ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca
     6661 agaaatgaag aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag
     6721 atgccactgg atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc
     6781 atcaactggc agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa
     6841 gcagcaaacg gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt
     6901 atcttttttt tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat
     6961 taagtaacgg aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa
     7021 aagcctatgc cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg
     7081 atccattgtt tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg
     7141 ttgctccagg agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt
     7201 tcccagaaac cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa
     7261 aacgagaatt gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg
     7321 aagccatcgc gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt
     7381 tacgtttatg gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc
     7441 aacctggaaa gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt
     7501 ggctgattgg aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg
     7561 atggcagttt ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc
     7621 aagaagaaat caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga
     7681 caaacaaagg gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag
     7741 agttaacgaa ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc
     7801 ttgaagttac gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt
     7861 tgcagacaaa gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc
     7921 aaggattgta cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag
     7981 aaaatgagca tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag
     8041 aagaagtaca gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc
     8101 aagaacatca tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc
     8161 tttccaaatt acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg
     8221 ctgcagatta tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa
     8281 aaagcatcgg aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa
     8341 aaaagaaaga agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac
     8401 tgaaaagtat ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca
     8461 cagcaatgaa aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag
     8521 aagtagaagg aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga
     8581 agcattacat cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt
     8641 gtaaggcagt agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag
     8701 ggtacttgag aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca
     8761 aaaaattcat cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt
     8821 cagatgagat tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag
     8881 gaagatgtcc aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct
     8941 tgaatccgga atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa
     9001 cgaatctcag agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg
     9061 gtaaaaaagg gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt
     9121 cttttccatg gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa
     9181 gaaaaaataa tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt
     9241 ccgaaaagtg agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa
     9301 cgttggggta ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca
     9361 ttcattttta aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct
     9421 aaagtatcct gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc
     9481 accaacgttg attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca
     9541 taaaacgaca agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc
     9601 ggctatgatc attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg
     9661 ttaagaatac gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt
     9721 tcgtaagaaa aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa
     9781 tgtacttact atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa
     9841 gtataaaatt agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga
     9901 attcatgggt gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt
     9961 acgaatgatc aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa
    10021 tcaatatgaa gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa
    10081 attatcaaaa tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta
    10141 aaagatgcaa atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa
    10201 gaactctatc ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa
    10261 catccttttc ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa
    10321 ttgaataatt gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt
    10381 accactagtt cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa
    10441 accgcaataa aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa
    10501 ggaatatgct gattttttta tgtttaatca tacaaaatag ttttttcata aaaatatgga
    10561 aaatatggat taattttgaa ataattgatt taaaaggaat acaaaagagt gaa
//
LOCUS       DAFLWC010000095        10273 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.097, whole genome shotgun sequence.
ACCESSION   DAFLWC010000095 DAFLWC010000000
VERSION     DAFLWC010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10273
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.097"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            179..328
                     /locus_tag="L1V17_002450"
     CDS             179..328
                     /locus_tag="L1V17_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HBN1237163.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            339..1853
                     /gene="dltA"
                     /locus_tag="L1V17_002451"
     CDS             339..1853
                     /gene="dltA"
                     /locus_tag="L1V17_002451"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HBN1237164.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            1850..3055
                     /gene="dltB"
                     /locus_tag="L1V17_002452"
     CDS             1850..3055
                     /gene="dltB"
                     /locus_tag="L1V17_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBN1237165.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            3100..3333
                     /gene="dltC"
                     /locus_tag="L1V17_002453"
     CDS             3100..3333
                     /gene="dltC"
                     /locus_tag="L1V17_002453"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBN1237166.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKG"
     gene            3336..4604
                     /gene="dltD"
                     /locus_tag="L1V17_002454"
     CDS             3336..4604
                     /gene="dltD"
                     /locus_tag="L1V17_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBN1237167.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            4745..5827
                     /locus_tag="L1V17_002455"
     CDS             4745..5827
                     /locus_tag="L1V17_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBN1237168.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            5827..6630
                     /locus_tag="L1V17_002456"
     CDS             5827..6630
                     /locus_tag="L1V17_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBN1237169.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            6700..7440
                     /locus_tag="L1V17_002457"
     CDS             6700..7440
                     /locus_tag="L1V17_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBN1237170.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            7451..8455
                     /locus_tag="L1V17_002458"
     CDS             7451..8455
                     /locus_tag="L1V17_002458"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBN1237171.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(8500..10197)
                     /locus_tag="L1V17_002459"
     CDS             complement(8500..10197)
                     /locus_tag="L1V17_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237172.1"
                     /translation="MKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLE
                     KPLDEANLLIKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTL
                     TVSSPYQNYAGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMY
                     KQKRLEYSLILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYY
                     WSRMFYYKKWYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLAC
                     IGEAYKNNRFYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISY
                     NLIDHILNTDKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLM
                     HTDQTKAKNYVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLP
                     EELPINDDDLAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYD
                     TNLFSRGITEELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT         3302 a         1697 c         2082 g         3192 t
ORIGIN      
        1 tatatttttt aaaagtacga gaaattataa agaaaaaagc agtgatttga tgtgctattt
       61 ttataaaagc tatgtgacaa aactgttagt aaaaaaacgg tttctgtaag ctagacacat
      121 gtttcttttt gtcaaaatta gttacacttt gtgtgaggtt atatgaggag ggaatccaat
      181 gaacaaatgg cgttctaatc caaaattgaa ttattgggga aaattcatca ttcgaacaat
      241 tttttatagt gcagtactgc tgttcctgat ttatctgtat cactataaaa atattcaagg
      301 aggaactttt atctataacg aattttagga ggaagagtat ggaaatcaaa acgattattg
      361 aagcaatcga tgattgggga ataaatgaac ctgatcgagt tgcttatcag gcggatgaga
      421 cgcatacttt tggtgaattg aaacaagcat cagacgcact tgcttattat ttagaaaaaa
      481 aggtagaagg cgatggacca attgtcgttt ttggcaattt ggagtttgaa atgattgtct
      541 catttctagg ggttgtcaaa tctggccatg cctatttgcc gattgaagag catacaccca
      601 aggagcgtat cctatcgatc tttcgggtgg ctaaaccatc tatggtcatc agtatcgggg
      661 actggataga agatattcct tcggttcctg tcataacaaa aaaagaattt caagaaatca
      721 agaagatacc agtaggattt tatcccagaa atagcgtaaa aggtacagaa aatttttata
      781 ttatttttac ttctggtact actggagaac caaaaggcgt acaaatcagt catgataatc
      841 tagtcagctt tgttcaatgg acgatggaag actttgggat caagcctggt atgcatttct
      901 tagcccaagc gccattttct tttgatttat cggtattttc tatttatcct gcattagttt
      961 ctggcggaat gctgaagccg ttaaataaag cagttgttca agactttcgt caattattcg
     1021 cgacattgcc agccttgaag ttgaatgtgt gggtttctac tccatcattt atggatattt
     1081 gcttgatgga acctacattc aatggagaaa atgtgccgga attggacatg tttttatttt
     1141 gcggagaaga attgacgaaa aaaactgcag aaagtctact tgatcgattc ccaaatgcac
     1201 ggatatataa tacttacggt ccaacagaag caactgtagc tatttcaagt attcagattg
     1261 accagcatgt actagatagt tatgaccgac taccgattgg ctacgtaaaa aaagacacga
     1321 aagtttctat tgtccaagaa ggtaaacctg tttcaaaagg agaaacgggt gaaatcatta
     1381 ttgcaggacc aagcgtatca aaaggttacc tgaacaatcc cgaaaagaca gctgctgcgt
     1441 tcttttgtca aaatgactta gcaagttacc atacagggga tgcaggtaga ctagatgaat
     1501 atgggctttt attttatgaa ggacgtatgg atcagcaggt caaattacat ggataccgga
     1561 ttgaactcgg ggatatcgaa cattatctgc tccaagacaa ccgaatcaaa caagctgtcg
     1621 tcgtaccaaa ataccaagga acaaaagtac agcagctggt tgcttttgtc gtattagaaa
     1681 acaaaacgaa acagccggat tttcagttga ctaaatctat caaagaacaa ttactagaag
     1741 ttgtaatgga ttatatgatt cctcagaagt tccattatgt cgatctgctg cctcagacag
     1801 ttaatggaaa aatcgatcga aaaaaattaa cagctgaggt gaatcctgaa tgatgttacc
     1861 tcatatgatc ccttatgcag agccgtttta tttttttctt ttagccattg cgcttgtacc
     1921 gatcgttcta tctttattga tatgggaaaa aagattacca gtttatcaat cagcagtgac
     1981 acttttcttt ttatttgtca gctttggagg taattattgg caacagggag cggcgctgat
     2041 tgggtatgtt ttgtggcaga cgatacttgt atggggctat tttgtttatc ggcaaaggaa
     2101 aaatcagaca ggatggtttt ttgccgccgt tattttagcg ataattccac tgtttttaac
     2161 gaaagtgact cctttttttg aacatggaaa agcatcgtta cttggttttt taggaatctc
     2221 ttatttaacc tttaaatctg tacaaatgat catggaaata agagatggca tgatcaaaac
     2281 atataagcca tttcgttata tccagtttct gctgttcttt ccaacaatct cttctggacc
     2341 aatcgatcgc tataggagat ttgaaaaaga tcagctccat ccgcctgttc gtgataaata
     2401 tgttgatctt ttgggaaaag gcgtccaaaa tatttttgtc ggttttttat ataaattcat
     2461 tatcggttat tattttggtc aagtactgct tcctgtagtg ggacgcattg ccttacagca
     2521 tggtggtatt tcatgggcat tagtaggtta tatgtacgtg tacagtatgt atttgttttt
     2581 tgattttgct ggctatagct tatttgcagt cggtacaagc tacatgatgg gatatcagac
     2641 accaatcaat ttcaataaac cttttttatc atggaatatc aaagaattct ggaatcgttg
     2701 gcatatgacg ctgtcctttt ggttccgtga ttatgtatat atgcgattga tgttcttcat
     2761 gatgaagaaa aaatttttta aaagcaagat cgtaatgtca aatatcggtt attttgcttt
     2821 gtttcttcta atgggtatat ggcatggatt gacgtggtac tacatcgtat atggactgta
     2881 tcatgcttgt ctgatctgtc tgacagatgc atggatccga tttaagaaga agcataaaga
     2941 gcagttgcct tctaacaaat ttacgcatgg cttagccgta tttttgacat ttcaagcagt
     3001 atgttttagc ttcctgattt tttcaggatt tttagataaa ctttttttta gctaacgaat
     3061 agtgacatat taatttatat aacaaaggag aaaaggaaaa tggaagaaca aattttatca
     3121 atcttagaag aaataacagg aacagatgaa gtaagaaaaa atcgtgatat tgatctattt
     3181 gatgaagggt tgcttgattc tttagcatct gttcaattat tagtcgagct agacggagag
     3241 ctggatatcc aagtccctgt atctgaattc gagcgagagg attggtgcac accgaataaa
     3301 atcattcaac aagcaactgc attgaagggt tgagtatgaa aaagaaactt tttgctattt
     3361 tcggcccggt tgttttagct gttggcttac tgtttgtgtt ttttacctcc tcctatcaag
     3421 tagatatctc taatccagaa acgattagac gtgcctcttc ttccatgtca gtgaacgtgt
     3481 tgaaaggaga tgcgataaaa aattatgcat tatctgaaaa acaatatatt cctttttttg
     3541 gctcaagtga attaagcaga atcagtccat ttcatccgtc tgttctggca gaaaaatacc
     3601 agcgaaacta tcgtccattt ttgctgggag cacccgggac acaatcgtta agccaatata
     3661 tgatgatgcg ttctgcagga gatgctatga aaaacaagaa agtcgtcttt attatttctc
     3721 ctcagtggtt cgttaaaaat ggtgtaaaaa ctgattactt taatacgtat tattctgaac
     3781 ttcaaacata cgactggttg ttttcaatga agaaagtaac gcctgctgat cgctatttag
     3841 ctagaagatt attaactttc tcaaaagtaa aagagaatga tacgttgacg gcgattctgc
     3901 aaacgatcaa aaaagggaag ctacctttac ctgaatcttt gaatcagctg cgcagccaat
     3961 ggaacatgct gaagagagag gatgaagtat tcagcaatat tgggttgaaa gatcgacagc
     4021 aaaaaatcga tcatgagtca aaacgattac caaaacaata ccaagaaaca gaattatcca
     4081 ttttagcaaa tcaaattgga gaacgagaaa cgacgaataa tccattcggg ttgaaaaacg
     4141 atttttatac gcatcgtatc cgagcccacg agccagagct caaacagtca caaaaaaatt
     4201 gggattatcg tttttcgcca gaattttctg attttcagct ggtcttggat caattagcaa
     4261 aaaaccataa cgaagtattg ttcatcatcc caccggttaa cgagaaatgg agcgattata
     4321 ccggactatc tcaagaaatg ttacaaggat ttgccaaaaa gatcaaattt caattaaata
     4381 gccaaggatt caatcgaata gctgattttg tcaatcaagc gggtaccaac tattttatgg
     4441 aagacacgat ccatctaggc tggaaaggct ggttggctgc agatcaacag atcagaccgt
     4501 ttttagaaga aaatcatatt actgctagta agtatcatct tgacgatgct ttttttagca
     4561 aatcttggca acatcaaata ccagataaac tacaattaaa ataaagaaaa caggcgagtg
     4621 ttgctcgctt gttttcttta tttttgaata ttctgaataa aagataaaaa taccaagttt
     4681 gcctgaacaa aaatcataag caatggtata atcacaatat gaatatagaa atgggggaaa
     4741 acatttggat acaaaagaag aacagctact tattgattta acttctgcaa aaggagtacc
     4801 tggaaatgaa gaagaggtaa gagaagtatt cagagaatat gccaaaccat tcgctgatga
     4861 tattttttat gacggtttag gcagtgtgat tgccaaacat ggtgctggcg gaggccccaa
     4921 ggtctttatt tctggacata tggacgaagt tggttttatg gtaacaaaaa taaccgaaaa
     4981 aggattcttg gaattccaaa ctcttggagg ttggtggggg caagtcatgc ttgctcagca
     5041 agttgaaatc aaaacacgtg aagggaaaat cgtccacggt gtgattggtt ccaaaccacc
     5101 acatgtttta acacctcaag taagaaataa accttatgaa ataaaggata tgttcattga
     5161 tattggcgca tcaagccaag aagaagccaa agagtggggc atacgtcctg gagatatggt
     5221 cactccatat attgaataca aacgaatgaa tggcagtaaa tatttactgg caaaagcatg
     5281 ggataatcgt atcgggacag ctgtttctct gcgagtatta gagaatctat ctaaagaagc
     5341 acacccaaat gttttattcg caggaagcga tgtgcaagaa gaagtaggct tgcgaggtgc
     5401 tcgaacaagt acacaccttg taaatcccga tattgctttt gctttagata ctggtacagc
     5461 aggagacact ccaggaatga caccaaaaga agcagattcg attttaggaa aaggcccaca
     5521 gattttgatt tttgatgcat ctatgatccc gcataaaaaa ttattgaatt ttgttattga
     5581 tgtagcagag gaaatggata ttccattcca atatacagtg atttctggcg gaggaactga
     5641 tgcaggacaa atgcatttga caagagatgg tgttccgtct gtagccatta ccgttcctgt
     5701 tcgttatctg cattcccata catcagtgat tcatgaagat gattatttga atacagtgaa
     5761 actagtcaca gaattagtga aacggcttga tagtgaaaca gttgaaaaaa ttcggagtta
     5821 tgaataatga ataatagaat acctatttct gaatatcgga aaaaagcacg agtttctttg
     5881 gaaaatcaat ggggaatcaa tacttggctt gttttcttat ctataatatt tacgagcgtc
     5941 atccagaact tttttgacgg tttcagtcct tttccggaag aaagcatgca gcagcactta
     6001 ttgagttttc tagtcgataa tttactttta ttcgcattca actatgcatt gttttacatt
     6061 gcgctagtag ttgtacgggg tggcagacca aaaagtaacc ttttattttc agttttccaa
     6121 agaaagtatt ttggttcgat acttggcatc aatttgatca attcagtcat caactggcta
     6181 ctcaacagtt taatctttct gcccatgttt ttaatcagcg gagtgagtac ttatatgcag
     6241 ctgcttttca gttcaaatgc ggtacctacg ggtgtcatgc cagaagattt tcttgatatc
     6301 agctttgttt tatcgatgat agggatgatt tttgtttcag cactcatcat gagtattgtt
     6361 ggcggtttat tccaatttgc tgcatggaca aagttcgact atcctgattt gtcggttatt
     6421 caatgtttga aatatggctg gtttttattg aaagatagaa ttggtacgta tattttgttg
     6481 cagctgtctt ttatcggctg gtatttgcta ggagcaatcg ctttgttcat cggtcttttg
     6541 tgggtcattg tttatgtgaa tgtgtcagtt gcagaatttt atgaacaagc acggattgaa
     6601 aaaggaggtc cagacgccta ttttacttag catgtaagca gtttattcat caaaaaaata
     6661 acttttgtgg taggataaat ctttgagggg gaatgtacga tgaaattaac tgttttagga
     6721 tgcttaggag cgtatcctta taaaaatcaa gggacaacag gttatttgct tcaatctgac
     6781 gggttcaatt tgttgatcga tgcaggtagt gctacgctga tcaaattaca agaacacctt
     6841 gatccacttg atctagatgc tgtgatcctt agccattatc atcatgatca tattgctgac
     6901 cttggtgtat tacagtatta ctggcaactt catcctaaga gaaatccgga gacattgctt
     6961 tcaatttatg gacacacaaa agattccatt cactttgaag aattgacgtt ggaaaatgtc
     7021 tcaaaaggac atccttattt tgaagctgaa gaattaaaaa ttggtccttt tctgattact
     7081 tttatggaaa caatccatcc agtagtatgt tacgccatgc gtatcgtaga agaaacaacg
     7141 gggaaagtat tcgtatttac aggtgattca ggttatttgg aaagtttcgc tgattttgcg
     7201 aaagatgctg atttgtttct agcagatacc tatctttttg aaggaaatga acatcatcat
     7261 gcccatttca cttcaaaaga agctggagaa cttgcgaaat cagctaacgt aaagaaactt
     7321 gtacttacac acctacctca gtttggtgat ttagaacaat tgaaaaatga agcgcaaaag
     7381 gcagcaggca aagggattga tatagaactt gctgcagttg acaaagtgtt taacatttag
     7441 gaggaagaac atgatttttg taccaaatga aaaccacgac ccaagaatca atttagcaat
     7501 tgaacaatat ttgctgcaag aaatgccttt agatgaacct attttgctct tttatatcaa
     7561 tgaaccttca atcatcatcg gcagaaacca aaatacgctt gaagaaatca atcgagatta
     7621 tgtggaagaa aatggcattc atgttgtccg tcgcttaagt ggaggcggag ctgtctacca
     7681 tgattttgga aacctgaact ttagttttat catgcctgat gatggggatt cattccgtga
     7741 ctttgcgaaa gtaacacagc caatcatcca agcacttcat gaattgggtg ttgctggggc
     7801 ggaattgaaa ggccgaaatg atctagtcat tgatggcatg aaattttctg gcaacgcgat
     7861 gtatgctacc aacggtcgga tgtttgctca tggaacaatt atgttcgact ctgatatcaa
     7921 tgaagtagtc aatgcattaa aagtaaaaaa agacaaaatc gaatcaaaag gaatcaaatc
     7981 gatccgttct cgtgtaacga atatcaaacc atttcttcca gaagaaaagc aaaaaatgac
     8041 aacagaagaa tttcgtcaag aaatcttgtt gaaaattttc ggcgtagagt cagtagaaga
     8101 agtaaaaacg tacgaattga ctgatgaaga ttggaaaaaa atcaatcgaa tctctgagga
     8161 atattatcga aattgggatt ggaattacgg gaagtctcca gatttcaatt tctctcgcca
     8221 aaaacgtttt tctatcggtt cgattgaagt ccatttgaat gtctcagaag gaatgatcaa
     8281 agaagcaaaa atctttggcg atttcttcgg actaggagat atctctgacg tggaaaaaaa
     8341 attggttgga cagaaatatg ataaagcatc tctatcaaaa atagtcagcc aaattgatgt
     8401 gaagaaatat tttggtgcga tagaaccaga agaattgctt accttacttt attgaaaata
     8461 aaaaatagcg gaatccacat atatggattc cgctattttt tatacaggat tcgggtaatt
     8521 tcgagagagt tgaacagtga tccgatcaat gaaagtatct ttttcctgcg ttagtgttcc
     8581 tgtgtaacga tccgctacgt ctttcatcat cattaagtca aaacgttcct gatcatctaa
     8641 ttcttctgtg atgcctcgac taaataggtt tgtatcgtaa tgtgcactat gttcgcaaca
     8701 aatgacgaaa tgttcctctt gttcgtgtat cgacaaataa atttttcgat acagtggatt
     8761 ttcgatggca tgagtttctc taaaggaatg ctctaaagcg tggatcaaaa gttgagccag
     8821 atcgtcatcg ttgataggaa gttcttcggg aagatctgct tggaaggtta tctgaatatt
     8881 ccgtttggca gctaacttct ggtaacgcgc taagataaga tttgtcacct ggtggttgca
     8941 aaaagaacac agcatttcga aattttttgc ttcttctaat atcttttcca catagttttt
     9001 agcttttgtt tggtccgtat gcattaaatc ttgcagattc tccatctctt ggacaaattc
     9061 caggcgaagt gtatttactt cttggatatg ctgtcgaagc tgctcataat gttgctccaa
     9121 caaatcattt ttgattttta agaaatctac ttgtctccga tctttgtcgg tatttaagat
     9181 gtgatcgatt agattgtagc tgataataac gattagaatg ataatatata aaatcgtaga
     9241 ccaattgatc gttgtttgat agatacctaa tgccgtttgg atgtaaatca agcaatggat
     9301 aatggctacc aagacgatcc aaggtgtaca agctacataa aaacggttat tcttatatgc
     9361 ttcgccaatg catgcaagtg aagtgactaa agtgcttata acactagcaa tattagcaat
     9421 cggcattaat tcaggaagtt ctgcaggagt aaaagttgca taaagcagaa cgccgataaa
     9481 aatcaaaagt tggaacgtac aaaaaattcc gtaccatttt ttatagtaaa acattcggct
     9541 ccaatagtag cagatgatga aagctgacgt taagataata aataaatgag ataaaaaaga
     9601 atgaacgaat ggttcaaaaa gaataccact taaaatatct tctgatacag cttcaaatcc
     9661 taatgccaaa gcaaagcaac ttaagagaat aagtgagtat tcaagacgtt tttgtttata
     9721 catcaagtag atcgtataga aaaaggtccc tatagcgata aaaacagcga ttatcatcgt
     9781 caatacttgc ggcactgatt gtgaataaat aaaactaatc aatggtccag ttgttcctag
     9841 ataaactttc ggtggcagtc cagcatagtt ctgataagga gatgagactg taagggtcaa
     9901 tttttttccg atataatttg ctggtaaatc tatcacagcc aatgagagtc cgggattgct
     9961 ttcttcctga taatctttcc gttggtataa aatcttttcg cctagatata cagtaatcca
    10021 ttgatggttt cctttgatta gtaaatttgc ttcgtccaac ggtttttcaa gtgtcgtttc
    10081 cataatgaat gtttcgtctt tatccacggt aggaatcgta cgagtgtact tgctgtcaaa
    10141 cttaaaatca ggatcatctt ttgtatagaa aacccacgaa tcttttattt ctttcatttg
    10201 attgctgtcc gcaggagaaa aaataaaata aaagaaataa gcaattcctg ttaaaaataa
    10261 caatgataat ata
//
LOCUS       DAFLWC010000096        10082 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.099, whole genome shotgun sequence.
ACCESSION   DAFLWC010000096 DAFLWC010000000
VERSION     DAFLWC010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10082
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.099"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(109..2229)
                     /locus_tag="L1V17_002460"
     CDS             complement(109..2229)
                     /locus_tag="L1V17_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBN1237173.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2459..3637
                     /locus_tag="L1V17_002461"
     CDS             2459..3637
                     /locus_tag="L1V17_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HBN1237174.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3653..4411
                     /gene="aroD"
                     /locus_tag="L1V17_002462"
     CDS             3653..4411
                     /gene="aroD"
                     /locus_tag="L1V17_002462"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBN1237175.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4434..4919
                     /gene="ybaK"
                     /locus_tag="L1V17_002463"
     CDS             4434..4919
                     /gene="ybaK"
                     /locus_tag="L1V17_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBN1237176.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4990..6243)
                     /locus_tag="L1V17_002464"
     CDS             complement(4990..6243)
                     /locus_tag="L1V17_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBN1237177.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6360..7709
                     /gene="gdhA"
                     /locus_tag="L1V17_002465"
     CDS             6360..7709
                     /gene="gdhA"
                     /locus_tag="L1V17_002465"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HBN1237178.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFISGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7821..9167
                     /locus_tag="L1V17_002466"
     CDS             7821..9167
                     /locus_tag="L1V17_002466"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBN1237179.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9475..9861)
                     /locus_tag="L1V17_002467"
     CDS             complement(9475..9861)
                     /locus_tag="L1V17_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBN1237180.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            complement(9910..>10082)
                     /locus_tag="L1V17_002468"
     CDS             complement(9910..>10082)
                     /locus_tag="L1V17_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HBN1237181.1"
                     /translation="VETVFSSLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQR
                     RFEGTLRYSLGY"
BASE COUNT         3215 a         1839 c         2053 g         2975 t
ORIGIN      
        1 ctgagccaga atgaggttca ttctgaccca gatttgattt tgtacaaccc atcagtcctt
       61 attgacaaag agcctaattt tgtcgctgct ccttttaaat ttattttatc attcggaaga
      121 acttgtggtc gttccgtgaa gttcttggta cgtttgcgtt ttataaagat caacagttga
      181 ttgtccgttg tgttcactaa agacactagt tgacttgtca ccaagagatt tttcagcttc
      241 ttttaatttc tctaagccat tcttgtagtc ataatcactg gtatcaattg ggtctaatcc
      301 actattcgta tagaaccgaa gaagatcacc attattgatt tggtcagaaa cagctaactg
      361 tttatcaact ttttctttca gtgaatcaat ttcattctgt acttcctcag taggttcagt
      421 aatagcttca ccagtttcgt tactatagat cgtaccaccg tagtaagtat attttggtgt
      481 aacaaaatca ccatcacgga aagaaacaag ctgttcatga tctttcgaga atagatcttg
      541 tcctaactga atataatttt ttgtatctac acctagtaag tgaagtaatg taggcaaggc
      601 atcaacttgt ccgccgtaag tgtgattgat tccgccctgt gtttgtccag ggatatggat
      661 catataaggg acacgctgca tttgtgcatt gtcgtagttt gtccaagtag aacttgtttt
      721 tccaactaat tcagctagat ttttatttct tgaattcgag acaccgtaat ggtcaccgta
      781 aaggacgatg actgaattat catacaagcc gctttctttc aaataattga agaattcttg
      841 tacggcggta tctaaataat tggctgtcgc aaagtaaccg ttgatcgttt catcatttgt
      901 attggctaac gggaatcctg cttcgtcatt ggtgaatttt gaataaggat aatggttaga
      961 tacagcaatg aattttgaat aaaatggttg ttgcagacgt tccaagtatt gtacggattg
     1021 ttggaaaaat ggtttatcat gcaacccgta ttggaacgaa ttgtcatcat taacatcata
     1081 ataagaagaa tcaaagaaat aatcatatcc taaattcttg tatgtctcgt ttcgattcca
     1141 gaatgtacca gcgttcccat ggaataccgc actagtgtaa ccttgtgttt gacttaaaat
     1201 atcaggtgca gcttggaaag tattttttcc gcctaattgt gtgaacaagg agccttgatt
     1261 caagccaaac aatgaatttt ccatcagcgt ttccgcatcg cttgtttttc ctgcttttac
     1321 ttgatggaaa aagttgtcaa aactgaacgt gctgttgctg tggtaaagac tattgatgaa
     1381 aggtgtaact tcatgctgga gaccattctc atctgtcaat ttataatcga tcaggaattg
     1441 ctggaagctt tctaaatgga tataaatcac attttttcct ctagcgagcc cgaacaaatc
     1501 gtcatttggt gctgcataat gttcttttac ataattttct acttctttca tatcattggg
     1561 acttgcttct gcccgcactt ggtttgtctg gtaagtttga acaccgtcat aaaccatgaa
     1621 agcattcaag ccaagatatt tgaccaaata atcacgagag aatgttcgag tcagcaattc
     1681 tggacgatca gcttccgcca taaaaagatt tcctgagaaa atcataactg ctaatgtaga
     1741 gatcgcaaaa gccattcttg ctcggatcgg gcgagggtcc aacttgattt tttttgcaat
     1801 cagcagaaca gtcaagataa taaaatcgat ccaatagatc acatcatatg ggcgaaacag
     1861 tcgaatggca ctttctccca gaccactcgc tactttccca gcacctaaaa tcgtgttgat
     1921 cgtaatgaag tccgtgaatt ctcgataata agtgacattc gaaaaaacaa gcaatgtcaa
     1981 aagaaaataa atgaccatca tcgtgatata agcaactcta gggcgtctga tataaagagc
     2041 aattccaagt aataacaatg tagttgcaat agggttgata aacaagataa agtattgaat
     2101 gccactttcg attccgagat ggaaatcaac taaataggca aaaatcgttt tcaaccaaag
     2161 taaaacgact agtaaagaaa aaaatccgag cctcttattc aaaaaggcag gtgtttttat
     2221 acatttcaag ataatcttcc tttctgcact tcttaatcac agaagtgtcc tgaaaccatg
     2281 ttacacagct cacttattct catttatttt actagtatga caatatagtg tcaattgaaa
     2341 ccagaagttt atgctgtttc attaaggttt tctttaagct tcatgaaaaa atgagcagta
     2401 agacaagtcc tatgtttttt gttatacttg ggaagagaaa gctaaagcag gtgaaggaat
     2461 gaaagtaaaa gtaaaaaaaa gagcaagcaa tcgattgaaa aaaggatatc cactgatcca
     2521 aaaagaagac cttgctcatc cccaaaaaga aaccacgcaa tgggtggaat tagttgattc
     2581 gcaaaaccaa tttatcgcaa aaggatatct aggaaagcag aataagggaa tcggttgggt
     2641 attgagccag cagaacatcc catttgatca atcttttttt gaagaatttt ttgtgaagtc
     2701 aaaagaaaaa agaactttct ttttttcaga tgattctact accgcttttc gtatattcaa
     2761 tggagaagga gacgggatcg gcggtctgat tgttgattat tatgcaggtt atgctgtttt
     2821 ttcttggtat aacgaaacgt tatatgcaca tcgtgaatta ttgattcaag cttttcgtga
     2881 aatctacccg gaaatcatag gaggctatga gaaaattcga tttgaatcag taaatctgcc
     2941 tgagagccag ttcatttacg gaaaagaggc accggaaccc ttgatcgtaa aagaaaacgg
     3001 agtaaaattt gccgtttatt taaatgaagg attaatgact gggatctttt tagaccaaaa
     3061 agaagtacgg ggatcattag cagaaggttt cgcttctggg aaaacagttt tgaacatgtt
     3121 tagttatacc ggcgcctttt ctgttgctgc cgcaatggga ggggcaatcg aaacaacaag
     3181 tgtcgatcta gcaaaacgca gtttaaaaaa aacacaggaa cagtttgaag tgaatggttt
     3241 ggatgtcgat cagcaaaaaa tcattgttat ggacgtattc gagtatttca aatacgccaa
     3301 aagaaaacaa tttttatatg acatgattgt attggatcca ccaagttttg ccagaaataa
     3361 gaaaaaagtc tttcgcgtag caaaagatta tggggaactg gtcaaggata gtctggatat
     3421 tttagcagaa gacgggatac ttattgcgtc tacaaatgct gcgaatgtct cgatagaaca
     3481 attccaaaca atgattgaag aggaattcca tgccaaaaat gtttcttttg aacaacttgc
     3541 tttatatcgt ctgccaaaag atttccagac gacggatacc tttttagaag gcaattatct
     3601 gaaagtgttt gtttatcaaa ttaaaaataa ccattagaag gagcgatgca gaatggttcg
     3661 ggtaaaggga ttgaatatag gaagcggtag accaaagatt tgtgcgcctc ttatcggggc
     3721 cgtccgagag gaagtattac gtgaagcagt tcttgcacgt gaagcagggg ccgatttagt
     3781 cgaatggcga gtcgatcatt atcgtgaagt tttttctttt gatgaagtag cagaaacatt
     3841 ggttcttatc catgagatgc ttgatggact gccgttatta tttacgtttc gtaccttagc
     3901 tgaaggcgga gaacaagaca tatcgatccg tcagtatcgc gacctttatg aacatgtgat
     3961 acacacagga ttagtagata tggtcgatat cgagttgttc aaagtagaaa gtctaggaaa
     4021 aagactgata gaggaaatca agtctttaaa cattccttta attatcagta gtcatgattt
     4081 taaagaaaca ccagcagacc ctgtcttgct ttaccgattg aatgttatgg aacattttgg
     4141 agccgatatc ggaaaactgg cagtaactcc caataatgaa cgagatgttt tgcggttgat
     4201 ggagttgact agacgggcaa atgcttttgt ctccatgcct attattacga tgtccatggg
     4261 aaatcttggt aaaatttctc gtctggttgg cggaacgacg ggttccgtta tgacatttgg
     4321 ttccttaagc agcgattcta cttctgctcc aggacaatta ccggtcaaag cattgaagca
     4381 aattattcaa ttattaaatg aaccgttgta gaacaagttt gaggtgatat tttttggcaa
     4441 agaaaaaaat agtaaaaacg aatgcaatcc gtatggtcga acaaaaaaag attccctata
     4501 cagagcacga atatgagtgg gacgaaagcc acctaagtgc gtcatcggtc gctgaacagc
     4561 ttccagaaag ccaatctcgt atatttaaaa cactggttgc tgtgggcaat gtgacggggc
     4621 ctcttgttgc tgtgataccg ggagaagccg aattgaatct aaaaaaatta gcaaaagttt
     4681 cagggaataa aaaagtagaa atgctccatt taaaagattt ggaagcaacg accggataca
     4741 tacgtggtgg ctgctcgcct ataggtatga aaaaactatt tcctacttat ttagatcaaa
     4801 ttgcagaaag ctatgaacaa atcattgtct cggctggcag aagagggcta cagatggagt
     4861 tagcacctca agatatctgt gcattaacga gcggacaatt tgcagatata aaacaataaa
     4921 tcatacgtat aaaagaaaga aggaggccgg gatgttgttt gtccagtctc cttctttctt
     4981 ttttatacat tatgctcttt gcccggcatt cattcctgct acatgccctg tagcgaaagc
     5041 cgctgtgata ttaaagccgc cagtataacc attgacatcc agtaattctc ccgcaaaata
     5101 cagaccatca atgattttac tctccaatgt tttaggataa atttccttta gagaaacccc
     5161 tccgccagtt acaaatgatt tctcaatagg aaaagttttg ttgattgata gcttaaactc
     5221 tttgcatagt tgaacaaaat cttgaatttg tttttgagag gcttgttgtc ctgtcagatg
     5281 atccatttca agccgctcaa gaaagaaaac taacaatcgc tcaggcaata taccatgcca
     5341 agcattgacc aagttctttt tggttgcttt acttttttct gtcaatatat gaataagctc
     5401 ttgtttggtt tgtgtaggga aacaatccag agaaagtgtc actggttctc ccgttttctc
     5461 taattcttta ttgacaaaac ttgaacaacg cagtgcagcc ggaccagaaa taccgaaatg
     5521 ggtgaaaagt aaatccatcg tatgttcagt caatacacga ccttttttat ttaaaacgcg
     5581 taaagtgatg tcttgtaaag aaagcccttg aagtgttttc tcctgaatat acggttcatc
     5641 cgatatcaag ggggactctg tcgcataaag aggcgtcacc gtgtgaccca ctcgcttcac
     5701 gatcttgtac ccatctccag tagaaccagt agatggataa gtccgtccac cagttgttaa
     5761 gataatggca ggagcatgga actcttcgaa ttccgtgcgt ataccgtaaa ttttatgttc
     5821 tttgtggatc aatttctcta ctcgagtaga gaatagaagc gtcacatcta gttctttcag
     5881 acgattgagc aatgcttcga taatcgtttt tgatttattt gttacaggaa acatccgtcc
     5941 atgatcctct tcttttaaat gtacgccttg tgattcaaag aagttcatga tatcgaaatt
     6001 attccattgc gcaaacgtac tatataaaaa ctttccattt ccaggaatat gtgcaatcaa
     6061 atcatcaaca ggacgattgt tcgtaacatt gcaccgacca ccacctgtca tcagtagttt
     6121 ttttcctgct tttttgtttt tttcgatcaa gagtacgcgt gcgccttgtt cagctgcact
     6181 gatcgctgcc atcatcccgc ttgttccagc gccgactacg atcacatcat acagtttttc
     6241 cattccctca cctcaaggaa agtgtagcat atctgaagaa agaaaacaga aaaaaatgtt
     6301 ttgagccaaa agagaaaatg agctaaaatg agggaagata agcaaaggag cgtggaacga
     6361 tgacaaacgc aacagaatat gttcaagcaa ttcaagaaaa gctacatcaa aaggatcaag
     6421 ggcaagaaga atttttacaa gcaatcgatg aattcatgcc cacggttatg tcttttttgg
     6481 acactcatcc cgaatatatc gaaaagaata tcttagaact tttaacggaa ccagaaagag
     6541 ttattcaatt tcgagtgcct tggcaagatg atgaaggaaa ctggcgagta aatagagggt
     6601 accgtatcca atacaactca gctatcggcc cttataaagg tggattgcgc ttccatccta
     6661 gtgtcaatct aagtatcttg aaatttttgg cttttgaaca gattttcaag aatagtttaa
     6721 ccggtctgcc aatcggtgga ggaaaaggcg gaagtgactt cgatcctaaa ggaaaatctg
     6781 ataatgagat catgcgtttt tgtcaaagtt tcatgctgga attgtcaaaa catatcggcc
     6841 catcgattga tgttcctgcg ggagatatcg gtgtaggagc tagagaaatc ggctatttgt
     6901 tcggcgaata taaacgattg aaaaaatatg atactggtgt gttgacaggt aaacctttgg
     6961 atttttgggg aagtaagata cgtacggaag ctactggtta tggattagtg tattatgtca
     7021 aacatctatt gaacgaagaa aaagattcat ttaatcaaaa aacagttttt atttccggaa
     7081 gcgggaatgt agccatttat gcaatcgaaa aagtgcaaga gctaggcggg aaagttgtta
     7141 catgttcaga ttctagcggg tacatctatg atccagaagg aatagatgtg aaactattga
     7201 aagaagtcaa agaaatcaat agacaacgtt tgacggaata cgcaaaccaa cgtccttctg
     7261 ctatttatca tgctggagaa tctgtttgga cattgaaaga aaaagcggat atcgctttgc
     7321 catgtgctac tcaaaatgaa atagacgaaa gcttggccga aatcttagta gaaaatggga
     7381 tcaaaatcgt agcagaaggc gctaatatgc catgtacagt aaaagctgtt tctgttcttc
     7441 atgaagcagg cgtgtggtat tgtccaggaa aagctgctaa tgctggagga gtagcagtat
     7501 ctgctttaga aatgagtcag aacgtccagc gattgacttg ggaaagagag caagtggatg
     7561 agcagctgga tcaaatcatg gaaacgattt accatacgtg tcgccaaaca gcagccgagt
     7621 acggcgacga aaaaaatctg cttcttggag caaatgttgc tggatttgaa aaagttgcca
     7681 aagcaatggc agcagaaggt ttagtttgaa aaatgaaact ttcttggaaa tattgtcagc
     7741 attttgttta tttgcttgaa aaataataaa aaaaaacgta aagtattacc tgtagagtaa
     7801 acctataagg aggagaacaa atggcacaca ttcattttga ctattcaaaa gtagcaccgt
     7861 ttgtcaacga acaagagtta gggtacatgc aaagccaagt aacagcagcc cacaacgaat
     7921 tacgggaagg tactggcgca ggaagcgact tccgcggctg gatcgattta ccaacgaact
     7981 atgacaaaga agaatttgca cgtatcaaag aagcagctaa aaaaatccaa tctgattctg
     8041 aagtattagt tgttatcggt atcggtggtt cttatttagg cgctcgtgca gcgatcgact
     8101 tcttgaatca cacattcttc aatttattag atagcaacac aagaaaagca ccacaaatct
     8161 tctttgccgg aaattcaatc agctcaacat atattgctga cttgatcgaa gtaatcggtg
     8221 atcgcgactt ttcagtaaac gttatttcaa aatctggaac aactactgaa ccagcgattg
     8281 cgttccgtgt attcaaagag cttcttgtta agaaatatgg acaagaagaa gcaaacaaac
     8341 gtatctacgc tacaacagat aaagcaaaag gtgcagttaa agtagaagca gatgcagaag
     8401 gttgggaaac tttcgtgatt cctgatgaca tcggcggacg tttctctgta ttaactgctg
     8461 ttggtttgtt accaatcgct gttagtggtg cagatatcga tgcattgatg caaggtgccg
     8521 ctgatgcaag caaagcatac tcaagcgaca aactagaaga aaacgaagct taccaatacg
     8581 cagcaatgcg caacattctt taccgtaaag gcaaagtaac tgagttgttg atcaactatg
     8641 aaccaggaat gcaatacttc tcagaatggt ggaaacaatt gtatggtgaa tctgaaggaa
     8701 aagaccaaaa aggcatctat ccttcaagcg caaacttctc aactgatttg cactctttag
     8761 gacaattcat ccaagaagga cgtcgcaata tttttgaaac agttgtgaag gttgaaaaac
     8821 ctcgtaaatc aatcacaatt cctgaacaag cagaagattt agacggtcta ggctacttgc
     8881 aaggaaaaga agtggacttc gtaaatacaa aagcatttga aggaacattg cttgctcata
     8941 cagacggtga cgtgcctaac ttgctagtca aaattccaga aatggatgct tatacattgg
     9001 gttatacaat gtacttcttt gaaattgctg taggtatttc aggttacttg aatggaatca
     9061 acccattcga ccaaccaggt gtagaagctt acaagaaaaa catgttcgca cttctaggca
     9121 aaccaggctt tgaagatctt gctaaagaat tgaacgaacg cctgtaagat aagggttttt
     9181 cgctagattt aaataatcag tgatagaaac atgttcgctt taaaatgaaa actggtaccc
     9241 atttaggtac tcaaacatac tgcatcgttt attcagaata aggggctgtg acaagacgtt
     9301 tgtcacagtc ccttgtttgt atagaaatcg attgattgcc ttgctcttta gtttgtttta
     9361 ggactttaag aacagtgagg ctgacttcga aggttaattc tgtttttttg ttttctagaa
     9421 tcagtaagca aaaaagcact cacttcgagt gcttttttgc gatatattct tagcttaaga
     9481 taggcctaat ttttctttta cagatgaggg taccttatcg ctggtaatta cttttttctc
     9541 tatgatccgc ttttcgcttg ctttcaactg caagatcgtt ccttcggggt aagcagaacc
     9601 attggcagag tcaccagaag taatgacatc gaaatctaac tgtctttttt caccgttttc
     9661 agcataagca tctacgttgt atttaaaacc tcttccaatt acttccccat tatctgcttt
     9721 gatatcagtt tctgcaggca ttggagcttt gactaccgca taataatctt tacctacata
     9781 agtagactga tagtagtccc aacctttcca tcctataaaa gcaatcaata tgataacgat
     9841 caaccctaaa atttttttca tgaaagatct ccttttttat ttttattata cccgtggtgc
     9901 tagttaattt taatatccta aagaatatct caaagttcct tcaaaacgtc gttgtgctcg
     9961 acttaataga acactgtaag ccagtaatat gctttcaaat ctactctcta gccctttaac
    10021 agaacgtgag ttgaaatttt gacaacctaa tttttctaag gaagaaaaaa cagtctcaac
    10081 tg
//
LOCUS       DAFLWC010000097         9732 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.100, whole genome shotgun sequence.
ACCESSION   DAFLWC010000097 DAFLWC010000000
VERSION     DAFLWC010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.100"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..244)
                     /locus_tag="L1V17_002469"
     CDS             complement(<1..244)
                     /locus_tag="L1V17_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBN1237182.1"
                     /translation="MSNDIQPEIRFPGFTEAWEQRKFECLLDKKDGVRRGPFGSALKK
                     EFFVSNSNFVVYEQQNAIYDNYETRYKITEKKYNELI"
     gene            complement(237..1829)
                     /locus_tag="L1V17_002470"
     CDS             complement(237..1829)
                     /locus_tag="L1V17_002470"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HBN1237183.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLANFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHE"
     gene            complement(2339..3064)
                     /locus_tag="L1V17_002471"
     CDS             complement(2339..3064)
                     /locus_tag="L1V17_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237184.1"
                     /translation="MKKKKLLWICLAILLIIGGIEIFTTYRLKTNQPKQYVSDMLNII
                     EEIDSEMKAFSKTSMDLGERYDFKGFMEDKMDEVSSREIPEGTPKAVRDTKDTLLEAI
                     DNVNTALLTNDVKLLEQGQLCFSIAQAIYTEFLDGNIKEKSLNEKLNSFVETYTAIPP
                     TWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNAVTEKVGKDIPLRLLENGKK
                     DYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(3218..3544)
                     /locus_tag="L1V17_002472"
     CDS             complement(3218..3544)
                     /locus_tag="L1V17_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237185.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQ
                     ILQEQYNLNRTCDDVTITHDNGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(3581..3946)
                     /locus_tag="L1V17_002473"
     CDS             complement(3581..3946)
                     /locus_tag="L1V17_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBN1237186.1"
                     /translation="MYCRKCGKEITNESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEQMGTILM
                     IAGVAGAIFGVLLGMSMSY"
     gene            complement(3983..4198)
                     /locus_tag="L1V17_002474"
     CDS             complement(3983..4198)
                     /locus_tag="L1V17_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1237187.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            4327..4662
                     /locus_tag="L1V17_002475"
     CDS             4327..4662
                     /locus_tag="L1V17_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1237188.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAKKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVDIDYEEEFLALYRSLSTEDAIRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(4738..6735)
                     /locus_tag="L1V17_002476"
     CDS             complement(4738..6735)
                     /locus_tag="L1V17_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237189.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFKHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVRDNSVKNALIENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPIYQFTSVTRDDGRRVRNRRDPIILN"
     gene            complement(6833..7108)
                     /locus_tag="L1V17_002477"
     CDS             complement(6833..7108)
                     /locus_tag="L1V17_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1237190.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            7340..8074
                     /locus_tag="L1V17_002478"
     CDS             7340..8074
                     /locus_tag="L1V17_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1237191.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            8113..9255
                     /locus_tag="L1V17_002479"
     CDS             8113..9255
                     /locus_tag="L1V17_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1237192.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
BASE COUNT         3190 a         1816 c         1423 g         3303 t
ORIGIN      
        1 tgattaattc attatatttt ttttcagtaa ttttatatct tgtttcgtaa ttatcataaa
       61 tagcattttg ttgttcatag acaacaaaat tgctattaga tacaaagaat tctttcttta
      121 aggcactccc aaatggtccc ctccttactc catctttttt atcaagtaag cattcaaact
      181 tacgctgttc ccaagcttcc gtaaatcctg ggaaacgaat ttctggttgt atatcattac
      241 tcatgtttga acacctccag cgcaccttgt aaccacgctt cattttcagg tgttgtttgc
      301 agggaagaga tagcttctaa aagttctttt tctagcactt gctgttcttg tcgtatcttc
      361 ttgatgtcat ttccgacatg aaccatatca attggttctt cttcttcaaa cgtatctaca
      421 tagcgtggaa tatttaagtt atagtcattt tctttgattt catcaaagtt tgccaaatga
      481 gcgtatttct cgacatcttt tctttcagca taggtttcga ggattttttg aatgttttct
      541 tccgataatt tattctgatt ttttcctttg acaaattctc gactagcgtc aatgaataat
      601 acgtctcgag tttggcggtt ctttttcaat acaatcaccg tcgttggaat cgatgtcccg
      661 aagaacaagt tcgcaggcat accgatcaca gcataaatac tgccgtcttc tagtaatttt
      721 tgacgaatga ccccttctgc agcgccacgg aataaaactc cgtgtggcaa gacgatggcc
      781 atagtccctg tttccttcaa atgatagaaa ccatgaagaa gaaacgcaaa atctgctttg
      841 gattttggcg ctaattttcc ataacgatta aaccgagaat cgtctaagaa ggtcgtatct
      901 gctgaccaat tagccgaata aggtgggttc attactactg catcaaatgt gtaaggttca
      961 tctgttggcc aatccttatt caacgtatcc ccattgcgga gattcatttc ttcggcatct
     1021 accccatgta aaatcaagtt catttttgct agattgtatg tcgttgtatt taattcttgc
     1081 ccatgatatt taacgttatc tgggtgagtt aagtagttac gcacatttaa catcaatgaa
     1141 cctgaaccca tggttggatc aaaaacacta aagaatcgtc gttctttttg atccaacgtc
     1201 acgatttgtg ccatcatatc agaaaccata tgaggcgtgt aaaattctcc ggctttcttc
     1261 cctgcttctg aagcaaattg actgatcaga aattcataag catccccgat cacgtcccca
     1321 tcgtgaccta aaacttccac gtcattcaat ttcttaatga cttcggtaat cgtcacattt
     1381 cgttgttgct catctgttcc tagttttttt gattggagat ccacatcatc aaataaccca
     1441 ttaaattgat tgtaggtaga tgccaattgc acaaaggctt tgtttagatc attcaattgg
     1501 aacgttgctt gttttgcttg atccgctaag acgttgaaaa gatactctgg cgaaatcgca
     1561 taccccaaaa tatcaacgat tgttgcaatc agatcttctt ttgattcttc atctgaaagt
     1621 aattcgcgat acaacatcgt ttgtttgctt accgtatcat attcctctaa ggattcatct
     1681 gctaaaagaa ccacttgttc caacaaacgg tcggataaat atttatagaa aatcagtccc
     1741 aataaataat ttttatattc tgacgcatcc attttgctac ggagattatc tgccgcacta
     1801 aataattttt gatttaattc tgcacccaaa aagatacact cctatctctt atttaaagtt
     1861 gctatatacc ctcttatttt agcatactcc cttttagaaa aagcaaaaaa aaaaagaaag
     1921 aaacttattc ttgctaataa actacgcgaa aggagtctaa cgttgtttga tataacttag
     1981 actgatcgtt aacttatttt ttatatttct acatagttat ctttagaacc atttcagata
     2041 catatgaaac aattacatat gattttttca taaaaaaaca gtactgtcta gtagtataaa
     2101 atatacaaat ttcttaaaaa ttttttcact aaaatcacta cctgaaacag tctaaaacac
     2161 ttatatatca acgtttaatg aaactatctc cgtttcattt cagatacaaa taaatatagt
     2221 cgggctccaa atccgaaaaa aaataccccc agtagcttat cctaagctac tggagatgta
     2281 taagtacggt catataacaa cggggtaggg taaataaatg aaaaagatgg aagaatcatt
     2341 attcaataac ttttttaaat acttcgttgt aatcagttac ctgtccgttc ttaaatacca
     2401 cagaataatc ttttttccca ttttcaagta accgaagtgg aatatcttta ccaactttct
     2461 ctgtcactgc attactgata cctgttagat tagctaataa atctgataaa gattgagcat
     2521 ctgtagaaat ctctgtatca gtatttatcg tgattccttt atcttcattt acaagtttcc
     2581 aagtaggtgg tatagctgtg tatgtttcta caaatgaatt aagtttttca ttaagtgact
     2641 tctcttttat atttccatct aaaaactctg tatatatggc ttgagctata ctaaaacaaa
     2701 gctggccttg ttctaataat tttacatcat tagttagtaa agctgtgttc acgttatcaa
     2761 tcgcttcaag aagagtatct ttggtgtccc taacagcttt aggtgtgcct tctggaattt
     2821 ccctacttga tacctcgtcc attttatctt ccataaaccc cttaaaatca tatctttctc
     2881 ccaaatccat agaagttttt gagaaagctt tcatttctga gtctatttct tcaataatat
     2941 ttaacatgtc tgatacatat tgtttaggct gattcgtttt taatctatat gtggtaaata
     3001 tctcaattcc tccaattatc aataaaattg ccaaacaaat ccataataat tttttctttt
     3061 tcatttttcc tcctatacac tgctgttata acagtgacta atgtaaagat tttcccagca
     3121 atcatcagac tattatttac agggaatcaa aaaaactcct tagtaagctt acacctttag
     3181 gagttcctgt ttgaacggta tgcataatac atttaaatca atttaacatt aacacctcag
     3241 tatatggtat ctctacatat acacggtctt tttttggata gtactcgaca tttatattga
     3301 tagcacttcc attgtctaac gtagctttag cccggtacgt gttatcacca ttatcatgag
     3361 tgatcgtcac atcatcacat gtccgattta agttatactg ttcttgtaaa atctgagtta
     3421 ccaatggtac agatgacttc tctagtccag atgaacccgt cattcttgaa aaaattatac
     3481 ctataatagc caatacaacg atacctataa tgacaaactt cttattcata tttactttat
     3541 tcaacttttt atctcctatc tccaaaatga ttttctctca tcagtaactc attgacatcc
     3601 ccaatagtac accaaagatg gctccagcta cccctgctat catcaaaatc gtacccattt
     3661 gttcatcttt ctctcgatat aagtaaccca taataacagc aacagcacca aataccacag
     3721 gaataaatgc taatgatact accatagaaa tccaaccaat aatcaaatac agcttccctg
     3781 tctcttgtcc atgtacgatt tgttccttca tttcattaat tgtctgctca gtacttttct
     3841 ttactgtgtc tgttccggtt gtctcatctg tttcttgtaa tgctccgcaa aactggcaat
     3901 acttactttc atttgttatt tctttaccac attttctaca atacatgtct tctcctccta
     3961 aaatcattca attgcttatt agctaactgt ttactttatt aaatacatca gaaaacagct
     4021 catttattgg tacacttaat atctcagaaa gcattttcat ttgatagggt ttaggaatcg
     4081 ttctccctgt ttgccacgaa cttacacatt gctgtgtaac attcattttt ttggctaact
     4141 cagtttggga aagtcctttt tcttttctgt atcggctgag attacttact tttttcatga
     4201 ttctcccctc ctgttttatt atatacaaca atatgatgta tttcaactca taaaatatat
     4261 aaatacttca aatgtcatta caaatacaac aacttgttgt actctactga gaaggggggt
     4321 gtattaatga aacagaagca atatgcaaag gtcattagag aaaagcgaaa agcactcggg
     4381 tggacacaaa aagaattagc taaaaaaatc ttctctacac aacaggcagt agcaagatgg
     4441 gaaaattctg taacagaacc taacctcgat agcttaacag ctctttctag agccctagga
     4501 acccctgtaa gccattttct agacaatgtt gacatagatt atgaggaaga gtttttggct
     4561 ctctatcgct ctcttagtac tgaagatgca attcgaacaa ttgactatat gaagctatta
     4621 aaaaggcaag aaaatgaacg caatcagcta ttgaaagatt gaaaaataaa taacccaccg
     4681 aactttaacg gtgggtgtat tgagatgaaa taagattaag agctatggat aacctgtcta
     4741 gtttaatata attgggtctc ttctattcct tactctccgt ccatcatctc ttgttacact
     4801 tgtaaattga taaataggaa ctaattcaac tcctgataat atcaattctt ttattacttc
     4861 atctatccct gcccctttcg ctagatatac taaaaaacta ctgcttgctt tcacattgta
     4921 tagtttctta atatccttag aagctcgttc aagagtgaat ccttgtttaa caaagtagcc
     4981 tctgttttct attaaagcat ttttcacgct gttatccctg acatttcgta ggcgttcaca
     5041 aacagtgtta ataagttctt tttctgtcat tagatatgtc ccttgccacg ataagccctg
     5101 taaaacttca tgtgcttcat ctaaaatcaa ttgtttttcc ttgctaagtt ctgatcggga
     5161 attttgagga aatactcttt tagcctcttt ttcgttaaaa catatcttaa cccattcata
     5221 agaaaaatat tgatatgtaa aatgaaattt ttccagaagt ggaaggatat cttcattcaa
     5281 tttttgaatc acagaagttg cattaaaaac gtctaatcga tagacattgc ttctcttatg
     5341 tttaaagttt cctaacgctt tctcttcctt taacctattt aggtattcga gcatcttcaa
     5401 aggaacatct tcatcatcta atttttttat caatcctata aaagtcataa gtgatagtaa
     5461 cttattacat ttatctatgt cataagtttt accatagtaa gaactcattt ttttagctaa
     5521 ttgttccccc gacaaaatac aagtcacact ttccttacta tcatcaaaaa aattaacatc
     5581 agaaagcaag acatcataga cacgtcgcat ttcctctaga taattcctta ttgtcctgaa
     5641 aagtttgtct ttcattgatt caagagtgtc aaaaagtact tttgattcct ctttcaattt
     5701 tcgaaaatgt gtaggataca agtctaggtt ctctaatagc caattaaatg tttctacccg
     5761 actgtctttc tttaaaatta gcatcacaac tccaataaaa ttttcactga tatcacaatt
     5821 actggaatga caataaaaaa tggaatgccc agttttactg gtaaaaatac tagcagaggg
     5881 attatgatcg ttgtgaaaca gacatcttaa gtttttactt gacttaagta atttattcat
     5941 atcaatggtt aacaatcttt cataaatctc attaaaagac atgtcggagg aatcaaacag
     6001 gcagtcttta aaccactgtt tcatttcttc tttgtcgtca ttttttatca acttaacaaa
     6061 atcggtttca ttgactagtt catactctct ccctgaatca ctttgacaat ttttagaaca
     6121 tgtcatggta aaatcaatcg gaagctcagt aatatctaac atgttgtctt cattaattat
     6181 tatcactgca tctgacttat atcctccaaa aaacattcta ttcgaagcat ttacattgtc
     6241 atcacacccg gggatgttct ttttcaagta ttcgtaaaca gcaaccattt taccatagtc
     6301 agtaattgct tcttttaata gaaagacaat cttgtatttt tctagatttt cagagtaccg
     6361 aatacttttt tgtatcgcaa acgcagaatt atgaactaaa ttgatagata aaaccttttc
     6421 tatgcttaag tatctactat catctttact caaatctact accttcccct tctcatcttt
     6481 aacagtgtta tcgacatcca gaataattac tctggtttcc acaaaactct ccttgtcatt
     6541 gcctttattc tttgtcttgc ttggaataaa tgattgtgat gaatttagta tctctacaaa
     6601 ctcatctctt gtaacttctc tatagttatc taaacaccta tctcttacat cagttttttc
     6661 tttttttgta actggcttct ctaataattt ttctttatct acataaattg gaatattaat
     6721 cattgatgtt tccatttgtg tttcctcctt ataaaattct gttaaagact aaaacataca
     6781 gataataaaa acaaactctt tattactata tgttttagtc ttatttgttt actcaacctt
     6841 tataccgttc catgaaacta tcaatatcag attttttaaa tctaatgacc gtatcaattt
     6901 ttataacagg taacccgtat tgagaaacat attttctaat cgttcctact gatacaccta
     6961 gatattcact tgcctgctga tagtccatat actctagagt gactccagaa ataatgtctt
     7021 ctagcatagg ctttagcact gtaattatct ctttcacttg ttgttcaact tgtatagaaa
     7081 caatgctatc aatgatttgt agagacatat ttccccctcc tttcgtgatt gcttgaacaa
     7141 attttctaag aattatcttc gtattttttg ctcaaaataa aagtattttg ttattaaccg
     7201 attaatcaaa caaaaaatga ttaccagttc atcgacatac acataatacc tcgataaaaa
     7261 aggggtgtca atagttttgt aaaatttatt tacaacaccc cttttttgag gtatactaat
     7321 tttaggaggt gtggtcaata tgataaaacg tccaccaata aattatttag aacgaaaaaa
     7381 gatactcgga acaaaaataa aagctataag aaagagtaaa aaattaacac aaccagcatt
     7441 tggtcttatg attaacaacg gtcaattaat tgacaaaaag actatctacg aatgggagaa
     7501 gggaacctat ttaccaatac cagagcgatt atcccgaatt gctgatttgg gaaatatgag
     7561 tatagaggag ttagtttgtg gcaatgtaga agaatatatt ttgggaatta ttctttatag
     7621 agatagcatt gtactagatg gtataacatt tccagataaa aacctgttcc agcatcttcg
     7681 tcaacagttc ccaccagtac actctaattt agatacatgg ctggatagat attccaaatt
     7741 agaaccagag atgcaagaat ttattgctaa caagacttgt aataaagtta aaaatgaaaa
     7801 aattagtctt ttcaatatct taaaaataga agaattattc atcaatgcta ttgtagaaga
     7861 atttgacaat aacattcttt tcctcactag cagtatagaa gaactactag aaagaatggt
     7921 agatgaatgg ctacctattc aattgaaaga catgtcttat cccgaagaag ctgtgagaga
     7981 aattactgat aatataaaca agctagaaca aacgatttca tcaattggga aaaaatacac
     8041 taagaaaaaa atgaagggag gtgataccat ctagtggtaa gtactccttg taaactaaga
     8101 ggagatgatt tcatggcaaa aatatcaaag tacaaaaaga aaaacggtca agtggcgtgg
     8161 atgtataaag gacacattgc caccgatcca cgaactggtg aaaaaataaa tactacgaga
     8221 agaggtttta gtagcaaaca agaagctcaa aaagattatg acgagtacag acatcaaata
     8281 ttatacggtg ttaaaaagaa agcacctgat atgacatttg aagacctgta taatgaatgg
     8341 ataactcatc agcgtaccag tgttaaagct tcaacaatcg caatctcagt aagatacgca
     8401 aataatcaaa tacttccagc atttggtaag cttaaactat cgaatatctc tgtcccatat
     8461 tgtcaaaaag tggtagatga atggcacagt aaatatgaaa gttacgatta tatgagaaaa
     8521 cagactgcac aaattttacg ctacggggtt gcaatgcaat atattgacaa taatcctatg
     8581 gaaaaaacac ttcttccacg aaaaaaagag tatgagaaaa atcgtaaatt ttactcaaaa
     8641 gaggagctta ataatttact ggatgctttt aaagattttg gtaacatgaa acaatacgcc
     8701 ttcttcagat tattggcata cacaggtatg agaaagagtg aagtactcgc tttacagtgg
     8761 aaagacatag acacgtttaa taaagaacta catgtcaata aaactcttgc tgtagatgaa
     8821 tttggtaaag ttataattca atctccgaaa acaagagctt ctagacgagt tatctcttta
     8881 gatactgaga ctctttctat cctcaacaac tggaaattac agcaaaaaga agagtattta
     8941 aaacttggat acaatactag ctctaaagag caacatgttt ttacaacagt taaaaacact
     9001 ctatacattc caaacactgt taatgattgg ttaagatata ttttgaaaaa atataacttg
     9061 cctcgtatta cacctcatgg gtttagacat acacatgcta gtttattatt agaagcagga
     9121 gaatctgtca aggtagttca acaacgatta gggcatgaaa atagtaaagt gacattagac
     9181 atctatgcac atattacaaa taatgcacct aagaaaacag gtcaagactt tgctgatatg
     9241 atggctcatc agtaaaagag ctggtcaaaa tctggtcatt tctagtatac aggcaaaaca
     9301 aaaaagctag aacccttata tatcaagggt tctagctcct ataacaggtt tacccaacac
     9361 tgccttccaa tgactctttt gggaatcaga ggaaagaatc aggctttata gagatatttc
     9421 atctaacaaa ttactttaga ctgacagtat atatcagcag gtactgtcat cgggaacgta
     9481 gccaatatcg tatccaaaac agcaggtaga gaagctattt gaggattcaa gttattctat
     9541 ttcaaccatg aagttaagtt cattaaaaat aaagatagtt ggtatttcaa taatttttgt
     9601 atagagttaa tcactttatt gatgctaatt catcttgatt ggtattataa tcgtattcaa
     9661 gttgcgtggc gtgcttttgc tagaaaatat ataactgttc tttataaaga aatataagga
     9721 ttaaacattt tt
//
LOCUS       DAFLWC010000098         9521 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.101, whole genome shotgun sequence.
ACCESSION   DAFLWC010000098 DAFLWC010000000
VERSION     DAFLWC010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9521
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.101"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            119..1108
                     /locus_tag="L1V17_002480"
     CDS             119..1108
                     /locus_tag="L1V17_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBN1237193.1"
                     /translation="MRDKEMRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAG
                     QYLFDKELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGA
                     MTICLSNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWET
                     CLNEFDKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFME
                     MQWINSNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVL
                     DQADFDLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
     gene            1090..1551
                     /locus_tag="L1V17_002481"
     CDS             1090..1551
                     /locus_tag="L1V17_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBN1237194.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLILMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAGINLPLLLELLMAQSAGKSIEEIDFKELLNNSQKSMVHINSLLKDVS"
     gene            1601..2065
                     /locus_tag="L1V17_002482"
     CDS             1601..2065
                     /locus_tag="L1V17_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1237195.1"
                     /translation="MIKLVRVDHRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVM
                     ALTIAKPADCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFG
                     GVSKKSESKQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            2079..2828
                     /locus_tag="L1V17_002483"
     CDS             2079..2828
                     /locus_tag="L1V17_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1237196.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMDQVKYGKREEAHG"
     gene            2828..3658
                     /locus_tag="L1V17_002484"
     CDS             2828..3658
                     /locus_tag="L1V17_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBN1237197.1"
                     /translation="MENSTEKKRLITKKDLNKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTSFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILAGFVLSIIGIL
                     "
     gene            3658..4305
                     /locus_tag="L1V17_002485"
     CDS             3658..4305
                     /locus_tag="L1V17_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBN1237198.1"
                     /translation="MIKALIFDMDGVLIDSEIMYQKWVFNFLKQENLSYPLYSYQKKI
                     GTTASIFDDIEKYNEGCNSLELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIK
                     MAIASSSPMDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEEC
                     LVIEDSYNGIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
     gene            complement(4403..5179)
                     /locus_tag="L1V17_002486"
     CDS             complement(4403..5179)
                     /locus_tag="L1V17_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1237199.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLAESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKADEFLANKLQINVTDRVYNIKRLMWEDGAPMGIDNFFASEEKFPTLFEKGS
                     QYTSLYKLLEDDYDVKATSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQ
                     PFHYSQSTVRCDRISYVIEVTENITLDTVHKNDSDPKVID"
     gene            5323..6282
                     /locus_tag="L1V17_002487"
     CDS             5323..6282
                     /locus_tag="L1V17_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBN1237200.1"
                     /translation="MTYTHLTTDELVIIESYFNIEKPVALVAQSLNRSRQTIYNVYSF
                     LKQGKKVLDYYRQYKQNKSRCGRRSTVLSDEQSTYVQEKVAQGWSPDVIIGRGEFPID
                     CSVRTLYRMFKKGLFDTQSLPMKGKRKPNNHQEKRGKQAFRRTIHERNSLYPHLTKEF
                     GHLEVDTIVGVKHKSAVITLVECLSKVIITLKPTGRRAEDIENRLNDWFKSMPKHLFK
                     SMTFDCGKEFSNWRSISNSNDIAIFFADPGTPSQRGLNEHSNGLLRRDGLPKTMDFRD
                     TDETFIQSVASKRNHIPRKSLNYRTPLEVFLSCIDKDILSSLI"
     gene            6399..6707
                     /locus_tag="L1V17_002488"
     CDS             6399..6707
                     /locus_tag="L1V17_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBN1237201.1"
                     /translation="MFQNKGQRYVTKGVMDSLPVELQALCWNLIDQNVQKQFHLDYLQ
                     IFEFSTEKGNQKLVHRQEEPEARKEYLISPKLRLKSVSQKIWVIDSGEYQTMLLPEEY
                     "
     gene            6734..7033
                     /locus_tag="L1V17_002489"
     CDS             6734..7033
                     /locus_tag="L1V17_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HBN1237202.1"
                     /translation="MLETAIEVLEKCAQLVTTPEEWGYESVTMEKEEIEMGMLPEDVT
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTNE"
     gene            7207..7758
                     /locus_tag="L1V17_002490"
     CDS             7207..7758
                     /locus_tag="L1V17_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HBN1237203.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFPRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            7904..8197
                     /locus_tag="L1V17_002491"
     CDS             7904..8197
                     /locus_tag="L1V17_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237204.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            8190..8486
                     /locus_tag="L1V17_002492"
     CDS             8190..8486
                     /locus_tag="L1V17_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237205.1"
                     /translation="MAKLIVLGGLIYGGYWLYKYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHAGYRHSWERIN"
     gene            8557..>9521
                     /locus_tag="L1V17_002493"
     CDS             8557..>9521
                     /locus_tag="L1V17_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HBN1237206.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKETVETDTTIEAKKSKTQS
                     TEQTTTEMKQSVEASTSESSIIESSSEEVKNTLWDSEKSTQLAIFVPQWGKTLGQEYK
                     SYNPQNNVSLYGTPLPSAVIDGNWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVET
                     GEYLGQHVYFFGFQNGQPKVYLTQQNQGNDKNYMYFNETQNQQLKQGFIDIVNGQTPQ
                     TPVVEESTQQATTTTTQSTSSSAISSWEAAKETVLNNKALWLYDSPDKNASNTNLIST
                     NEYMKDLMQDENGSYYSINIVTDDNGNTTMAGGKQFRVYTDGRIS"
BASE COUNT         3365 a         1366 c         1785 g         3005 t
ORIGIN      
        1 cattttatta tataaaattg ttataaaaaa atttttttga aaaatagtat tgcaaaataa
       61 agcaatttca tagataatag gtattgtaaa gttatatgac tttataatac ttattagagt
      121 gagggataaa gaaatgagac aactacacaa agaacagatt gaaacagcaa tggcagcgtt
      181 aaaggaaaag acaattgatc atgtatattt tacagcatgt gggggttcac aagccgtttt
      241 aatggctggt caatatctat ttgataaaga attaactgta ccttgtcatg tttatactgc
      301 taacgaattt aactatgcta taccaaaagg attatctgaa aattctttag ttatcacttg
      361 ttcccattct ggcacaacac cagaaactgt agaagcaaca aaaaaagcaa gagaatttgg
      421 agcaatgact atttgtttat ctaatgaaga aggatctcct ctatgggaag cagctgaata
      481 tcctgttcac tatgattggg gtaaagatgt tgatgctagt gatttaaata aaggaattct
      541 ttatggttta ttatttaata ttttacttgt tttagatggc tctaaaaaat gggaaacttg
      601 cttgaatgaa tttgataagt taaatgatct tgttattgct gaaaagagca aatttgaaat
      661 aactgctaaa gaatggggta aaaaccaaaa acgagataaa attatttaca caattggtag
      721 cggtatcaat tacggagaaa tttactccac agcagcttgc tggttcatgg aaatgcaatg
      781 gattaattct aatgctattc attctgggga atttttccat ggtccttttg aaatcactga
      841 ttatgatgta ccattcatct tagtgaaaag tattggagat acaagatttt tagatcaacg
      901 ggtagaagac ttcactaaaa aattcagtaa taaattaatg gttttagacc aagctgattt
      961 tgacttagaa tctatagata gtgtagcgaa agaatatatt gcagctgtac ttagtggcgt
     1021 tgttattcgc caaatggtag aagcgattgc ttttgaaaga ggccattcct tagatgttag
     1081 acgctatatg tggcaaatga aatattaatt aataggaggt tgcaaaagat ggcaaatcaa
     1141 ttatttcaca ttgtgattac aacacattct accctttgtg agggttattt aaaggcaaca
     1201 aaattaattt taatgaatga cgccacaggt attagtgctg ttccatttaa agaaaatact
     1261 agtccagatg attttgagga gagtatgaaa gaaataatta gtcagcatca tttgcaacct
     1321 ctaattattt taacggattt aattggagga acacctaata atgtttctat taaacagttg
     1381 aacaacaata gaattcaaat tattgctggg attaatttac ctcttttact ggagttatta
     1441 atggcccagt cagctggtaa atctatagaa gaaatagatt ttaaggaatt actgaataac
     1501 tctcaaaaaa gtatggttca tattaattcg cttttaaaag atgtcagtta aggtggcaat
     1561 ttctattcta taaattttaa aaattgaagg aggaaataga atgattaaat tagtgcgtgt
     1621 agaccacaga ttacttcatg gacaagtaat attttcttgg actaaacagt atgatattaa
     1681 ccatattatt gtggctgata acaaagttcc aggagatcca atgtctgtga tggctttgac
     1741 aattgctaaa cctgctgatt gcaaattaga cattgttaaa attagtgatg ttaaagggat
     1801 tatggaaaca tccccaaatg ataattacat gattttaatt aaaggaccta aggaagcttt
     1861 tgaattagtt caaaatttac cagaaattaa agaaattaat tttggcggtg tgtctaagaa
     1921 aagcgagtcc aaacaatatg gaaaggcagt ctttttaact cctgaagaat tagaagccac
     1981 aaaaaaaatt cttgatcaag aagtgaaaat atttgtgcaa caagtcccat cttcaagtat
     2041 tgaaaatgta gattttagta agtaaggggg gaaaataaat gttattaaaa gccattttat
     2101 taggtttagt tggtgtggta gctgttattg actccaggtt aattggtcga caaaatattg
     2161 gtagaccact aattttgagt acacttgccg gacttgtgct aggtgacttg catacaggga
     2221 ttgttcttgg ggcatcttta gaattaattt ctatgggatt cgtctcaatt ggggcggctg
     2281 gacctcctaa tatgcaactt ggtagtatta ttgccactgc ttttgcaatt ttaactaata
     2341 gtagtacaga aacagcctta acaatagcta tcccagtggc tgtagctggt gaatttatga
     2401 gtattatcat gcgcatgata attgctcaat ttggacatgc tgcagataaa gccattgaaa
     2461 ataataaatt tagaaaagct caaattattc atatttattg gtcatttatt tttaatgctt
     2521 ttgtttactt tattccaatc tttttaacag tatattttgg tgctgacgtt gtggcagatt
     2581 tagtagataa aattccagaa atgattacag acgccttgac tgtctctgga aatatgcttt
     2641 ccgcattagg gtttgcaatg ctattaagca caatgttgag taaaaaatta tatccttact
     2701 ttatttttgg attctttatt gttgcctatt caggtctttc actaattggc gtgacaattt
     2761 ttgcagctct gattgccttt gtaatggatc aagttaaata tggaaaaaga gaagaggcgc
     2821 atggttaatg gaaaatagta cagaaaaaaa acgtttaatc acaaaaaaag atcttaataa
     2881 gatgtgtctt cgttcatgga caatcatgtg ttcgtggaat tatgaaagac aaatgcatat
     2941 gggatttatg tatgggatgg cgccaatttt aaataaagtt tataaaaatg atgaagagaa
     3001 aaaaagagaa gcttatactc gtcatatggc attttttaac tgtacgcctc aaatgacttc
     3061 atttattatg ggactttgtg cttctatgga agaacaaaat gctcaagcag aagaaggaaa
     3121 ctttaatact gaatctatct ccatgattaa aaccagttta atgggtcctt ttgctggaat
     3181 tggtgattca tttttccaag gtactttaag aattattaca tttgggattg gattgtcttt
     3241 tgctaagcaa ggtagtattt taggaccgat tttagctgtt ggcctttttg ctataccttc
     3301 tattttagct gttttttacg gcggtaaatt aggatatgag tctggcaata aataccttac
     3361 taaattgtat caagaaggtc ttatggatcg agtaatgcaa tttgcttcta tcattggttt
     3421 ggctgtagta ggtggaatgg tggctagcat ggtgccaatt gtcacccctt taaaattcac
     3481 tacaggggga acagaacttg ttttacaaga cttacttgat tccattattc ctggattatt
     3541 accacttgta tgtactttgg gaatatataa attgattaag aaaaatgtta gtacaaatat
     3601 gctcttatta ggttgtattt tggcagggtt tgttttaagt ataataggta tcttataatg
     3661 attaaggctc taatttttga tatggacgga gttttaattg atagcgagat tatgtatcaa
     3721 aagtgggtat ttaatttttt aaaacaagaa aatttaagct atcctttgta ttcttatcaa
     3781 aaaaagattg gaactacagc aagtattttt gatgatatag aaaagtacaa tgagggatgt
     3841 aacagtttag aattgaaggg aaaatttact aaatattgga aatcgcaaaa gattgattac
     3901 ttggatattt ttcctaatat actaattgaa cagcttgaat ggttaaaaaa gaaaaaaata
     3961 aaaatggcaa ttgcttcttc cagtccaatg gatactataa atgaagttgt taccacttgt
     4021 aaaatagagt catattttga ttgtttaatt agcggaagag atttgccaga aagtaaacct
     4081 aatcctacta tattccttaa agcttcagaa cagctcagaa ttccagttga agaatgtctg
     4141 gtgatagaag attcttataa tggtataaaa gctggtaaaa gagcaaatat gaaggttctt
     4201 gcaattaaag ataaacgttt ttctcaagat gtaagtctag cagatgatgt tatttacgat
     4261 attaaatatc tgcgacaaga agtacaggtg aaatttggaa tataaataag ttttttgatg
     4321 tatttagaga atattagtaa aaataaaaat catgcccaaa tctaatcaaa attgattgct
     4381 ttgggtatga tttcttttaa tatcaatcta ttactttagg atctgaatca tttttatgca
     4441 ccgtatctaa agtgatattt tctgtgactt caataacata actaattcta tcacaacgaa
     4501 ctgtggattg agaataatga aatggttgat tatttttatc tttgccaacc ttttctaaaa
     4561 taaatagcgg atctcctact atacattgca ataagtcgga aagctcaggt gttgcagata
     4621 aaccgtttat ttccataata gagctcgtag ctttgacatc atagtcatct tctagaagtt
     4681 tatataatga agtatattgg ctaccttttt caaataaagt tggaaatttt tcttctgatg
     4741 cgaaaaaatt atcaattccc atcggggcac cgtcttccca cattaaacgt ttaatattgt
     4801 aaactctatc agttacattg atttgtaatt tattagctaa aaactcatca gcctttataa
     4861 ttttagaatg taaaacagta tatctaattt tatgtcctcg ggtagaaaga gaatcgctaa
     4921 atccatgaac tccagctaat tttaaacttt cttttttttg agttacaaag gtccctttcc
     4981 cccttaatcg ttcaactgtt ccactttctg ctaaaagttt aaaagctttt cgaatggtaa
     5041 tcttacttac tccataaatt ttacataatt cttcttctgt aggtaattgc tctcctggaa
     5101 gatatttttt ttcacgaata tcgttacgta tagaagcttc tacttgtaaa tataatggtc
     5161 tattatcttg aaaattcata gtacactccc taaaaagtta tacttcatta tatcacaatt
     5221 tattaaaacg tcgattgtaa aattaagcta gacaactaaa aagatcattt gtgctacact
     5281 caaaatagtt ccgaccaaag aattaataag gagtgagtac aaatgactta cacccatctt
     5341 acaacagacg aactagtaat catagagtct tatttcaata tcgagaaacc tgtcgctctt
     5401 gtcgcacaaa gtttaaatcg ctctagacaa accatttata atgtttattc gtttctcaaa
     5461 caaggaaaaa aagtgctaga ttattaccgt caatacaaac aaaataaatc tcgttgtgga
     5521 cgacgttcaa ccgttttatc tgatgaacaa tcaacatatg ttcaagaaaa ggtagctcaa
     5581 ggatggtcac ccgatgtgat tatcggccgt ggcgagtttc caattgattg ttctgttcgt
     5641 acactctatc ggatgtttaa aaaaggcctt tttgacacac agtcgttacc tatgaagggg
     5701 aaacgtaaac cgaataatca tcaagaaaag cgtggaaaac aggcctttcg cagaacgatt
     5761 catgaacgga acagtctcta tccacacctg actaaagaat ttggtcatct cgaagtcgac
     5821 accattgtgg gagttaaaca caagagcgct gttattacat tggttgagtg tttatccaag
     5881 gttattatta ctttgaaacc gacaggcaga cgagccgaag atatcgaaaa caggttaaat
     5941 gattggttca aatccatgcc taaacacttg tttaaatcca tgacatttga ttgtggaaaa
     6001 gaattttcca actggcgatc tataagtaac tcgaacgata ttgccatctt tttcgcagat
     6061 ccaggaacac cttcgcaaag agggctaaat gagcactcaa acggcttgct tagacgagat
     6121 ggcttaccta aaacaatgga ctttagggac acggatgaaa cctttattca atccgttgcc
     6181 tcgaaaagaa accatattcc aagaaaatca ttaaattatc gaacaccatt ggaagtattt
     6241 ttgagctgca tagataaaga catattgtct agcttaattt gacaaatcag atagtataaa
     6301 atgaatcaaa ttgaatatca aatatatatt atatccatga agcccaatct tctttaatag
     6361 aagattgggc tatttttatg gcaaaggagg gaaaagaaat gtttcaaaat aaaggacaac
     6421 gttatgtcac aaagggagta atggacagtt tgccggtgga attacaagct ttatgttgga
     6481 atctaatcga tcaaaacgtt caaaagcaat ttcatttaga ctatcttcaa atctttgaat
     6541 tttctacgga aaaaggaaat caaaagttgg ttcatcgtca agaagaacca gaagcaagaa
     6601 aagagtatct gatttcacct aagcttcgtt tgaaatcagt gtctcaaaaa atatgggtca
     6661 ttgattcggg tgagtatcaa acgatgttat taccagaaga atactgatat ctaaaagaaa
     6721 ggaacgaaag gacttgttag aaacggctat cgaagtactg gaaaagtgtg cacagctagt
     6781 cactactcct gaagagtggg gctatgaatc cgttacgatg gaaaaagagg aaattgaaat
     6841 gggtatgctt cctgaagatg ttactctacc acgtttagtg atgacacatc tttatattta
     6901 ttgcgcacca gaagatggaa aagactatgt agtttatttc attacagata ttaccagcca
     6961 gcgagaattt gttcgtgggt tactggtaga aggacgattg gtttggagtc agattggagg
     7021 aacgaatgaa taagatcgat tatttgagaa tgattgcgaa atgtttagaa gatatcctta
     7081 cagcgattca tcaaattctg aagaaaaaag gagaaagaat atgaaatatt ttcaactagt
     7141 attgacactt ataacggcaa tggtgattga attgcttgaa caaaaattag cataggagaa
     7201 aaagagatga ttgaaaaaga attagtgacc acacaaacag aagtttggcg agatcctcat
     7261 catacccatc gctatgtttt caaacgacaa tgggcgatca aaggaaaaga agcggaagat
     7321 aaattagcgg tagtcattac tattcgtcca acagatacag aaccatttac gaatgatttg
     7381 agtatgttat taatcgaaaa gaatatccga caattaggat ttactggttt tattgctgtg
     7441 aatctttttt cgtatacaaa agcgaaaagt cctcgggtat ttcctcgtgg aaatgatgaa
     7501 caatctttgg aaatattaac aactgttttc acagaaaaga aaatcaacac cattattttt
     7561 gcttgtggtt cgattacagc gacgagtcaa gtggcttatg aacaagcgaa gaccatttac
     7621 gatcaattga gtgcgaaaca aaaaaagatg accaaagtat tgataaatgc agaaggtaag
     7681 ttatcccacc cactaagtat tcatgttcgt aatgaatggc aattggcaga tagtcaatta
     7741 ttatttcaag aaaaataaca ttttattttc ttatgttact tataagtagt tttacatgct
     7801 ttttgacttt aaaaatacat gtgatgatac atgttatatg aattatcaat gtacccagta
     7861 atatgctatt ttcattatgt aaaaaataac agggggtgtg tagatggaga ttgatgaaac
     7921 ttgtttgagt aactcttata aaagtatgaa tgactttttt gaggaaatgg aactggattc
     7981 agaattgctc tatcaatttt atcttgcttt tcgagggcaa cagatttctt ttccaatgaa
     8041 aatgtacgat cgtgagttag ttagaaaaag aatcgaaaac atgatagaac aggaaaaaac
     8101 tgtagatatc cgtcaattga cagaagttta tggtttctct gcaagatgga ttcaaaaagt
     8161 aattaaacaa aaagaaagga gacgagtaca tggctaagct gattgtatta ggtggtttaa
     8221 tttacggtgg atattggtta tataaatata tgcttgcgca tccgaatata gataaaggaa
     8281 aagtaattaa gacagttggg gtaatcatag ttggactcat agctctaact aagaaaaata
     8341 atactaatag cccaaaaata atgagaactt atcgctgtag aggatgtgga agggaaattt
     8401 ctactagttt taatccatct gaaagccctc aaggaagaga tcgttgtcat gctggctatc
     8461 gacattcttg ggaaaggatt aactaaatga acaccattga gattaattga ctgataaaat
     8521 aagtacgcga gggagaaatt gaaaggggga aataaaatga aaaaatggtt gttattacta
     8581 attggaatgg ggattttatt cactggttgt acatctgaga atacgaggac taaagagact
     8641 gtagaaactg atacaacaat tgaggctaaa aaaagtaaaa cgcaatcaac tgaacaaact
     8701 acaacagaaa tgaaacaatc tgtggaagca agtacaagtg aaagttcaat cattgaatct
     8761 tcttctgaag aggttaaaaa tactttgtgg gatagtgaga aatctactca actagcaatt
     8821 tttgtcccac aatggggaaa gacattaggt caagaatata aaagctacaa tcctcagaac
     8881 aatgtaagtc tgtatggtac gcctttacca agtgcagtta ttgatggaaa ttggaaaatg
     8941 gcaatcaatg aagcaccagt taccgtacaa tggtcagaag atggaactgg tcatgcagat
     9001 ttcaatttag tagcagttta ttctgatgta gaaactggag aatatttagg gcagcatgta
     9061 tatttctttg gctttcaaaa tggacaacct aaagtttatt taacgcaaca aaatcaaggc
     9121 aatgataaaa actacatgta cttcaatgaa actcagaacc aacagttaaa acaaggtttc
     9181 attgatattg tgaatggaca aactcctcaa actccagtag tagaagaatc tactcaacaa
     9241 gcaacaacta caacgacaca atctacaagt agctcagcaa tttcaagttg ggaagctgct
     9301 aaagaaactg tactaaataa taaagcttta tggttgtatg attctcctga taaaaatgca
     9361 tcaaatacta atttaattag cacaaatgaa tatatgaaag atctaatgca agatgaaaat
     9421 ggaagctact attcaattaa tattgtaacg gatgataatg gaaatacaac aatggctggt
     9481 ggaaaacaat tccgtgttta tacagatgga agaatttctc a
//
LOCUS       DAFLWC010000099         9515 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.102, whole genome shotgun sequence.
ACCESSION   DAFLWC010000099 DAFLWC010000000
VERSION     DAFLWC010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9515)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9515)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9515
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.102"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            45..947
                     /gene="gnd"
                     /locus_tag="L1V17_002494"
     CDS             45..947
                     /gene="gnd"
                     /locus_tag="L1V17_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HBN1237207.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            949..1950
                     /locus_tag="L1V17_002495"
     CDS             949..1950
                     /locus_tag="L1V17_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBN1237208.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALIERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            1947..2231
                     /locus_tag="L1V17_002496"
     CDS             1947..2231
                     /locus_tag="L1V17_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HBN1237209.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            2264..3061
                     /locus_tag="L1V17_002497"
     CDS             2264..3061
                     /locus_tag="L1V17_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBN1237210.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            3075..3908
                     /locus_tag="L1V17_002498"
     CDS             3075..3908
                     /locus_tag="L1V17_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBN1237211.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            3926..4783
                     /locus_tag="L1V17_002499"
     CDS             3926..4783
                     /locus_tag="L1V17_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBN1237212.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            4805..5314
                     /locus_tag="L1V17_002500"
     CDS             4805..5314
                     /locus_tag="L1V17_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBN1237213.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            5351..5752
                     /locus_tag="L1V17_002501"
     CDS             5351..5752
                     /locus_tag="L1V17_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237214.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            5864..6217
                     /locus_tag="L1V17_002502"
     CDS             5864..6217
                     /locus_tag="L1V17_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237215.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            6251..6694
                     /locus_tag="L1V17_002503"
     CDS             6251..6694
                     /locus_tag="L1V17_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBN1237216.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            6711..7796
                     /gene="uxuA"
                     /locus_tag="L1V17_002504"
     CDS             6711..7796
                     /gene="uxuA"
                     /locus_tag="L1V17_002504"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBN1237217.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            7789..8502
                     /locus_tag="L1V17_002505"
     CDS             7789..8502
                     /locus_tag="L1V17_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBN1237218.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(8709..8858)
                     /locus_tag="L1V17_002506"
     CDS             complement(8709..8858)
                     /locus_tag="L1V17_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237219.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            9254..9454
                     /locus_tag="L1V17_002507"
     CDS             9254..9454
                     /locus_tag="L1V17_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBN1237220.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         3195 a         1495 c         2113 g         2712 t
ORIGIN      
        1 aaattttttt gtataatgag ggtataagaa atggaggcgc tatcatggaa attggtgtaa
       61 ttggtttggg aaaaatggga ttgaatttag ctttaaactt aaaagagcac catcacaaag
      121 tacaaggact cgacatttca agtacagctg ttagtcaggc aagagaaaat gacattcctg
      181 cttatcaaga gatctctgaa tttctagcta cttttgagca gaaaaaaatc atctggttaa
      241 tgcttcctgc tggagagata accgaaaaca tgttaagaaa actttttcca aaactcggac
      301 caggagacat tattattgaa ggcggaaact cttattataa agattcaatc cgtcgagcag
      361 aagagtttca gaaaaatgaa atcggttact tggattgtgg gacttctgga ggaatcgaag
      421 gagcacgaca tcaagcctgc ttaatgattg gaggagataa agaaactttt ctatccgtgg
      481 aacaattatt caaagatgta gcaattgaaa gaggatatct gtatgctggt gcatccggaa
      541 gcggacactt cttgaaaatg atccataatg gaatcgaata tggaatgatg caagcaatcg
      601 gtgaaggatt ccaacttgta caaaaaagtg agtatgcttt tgacttggaa caagtcgcac
      661 gtgtttggaa tcatggttcg gtgattcgcg gctggctgat ggaaatcatg gaagatcagt
      721 taaacgaaca tcccaattta agtaattatc ggggaatcgt ttctgcatca ggtgaagcaa
      781 aatggacggt tgaaacagcg ctagaaatgg ctgttccagt tccagtaatt gcaactagtt
      841 tgttcatgag gaatctttca caggaagaag atagtttttc agcaaaagta gtttcagcac
      901 taagaaatgg gtttggcgga catgaaatag ttgaaaaggg tgagtaaaat gccagattat
      961 catatagcaa tcgttaattc cagcagtttc ggaagagtct ttccacacca cttggaaaga
     1021 ttaaagtcag ttggagacgt tcatttcttt actgttgatc aagagattcc aggaaaagaa
     1081 ctagcggagt tacttaaagg attcaatatc attattgcaa gtgttacgcc attttttcga
     1141 cgagattttt ttgaaaacaa agatgaactg ctattgattt cccgacatgg tattggttac
     1201 aacaatattg atttaaaagc agcaaaagaa caccagacaa tcgtatctat catacctgct
     1261 ttaattgaac gaaatgctgt agcagaaaat aatataacta atttgttgtc catgcttcga
     1321 cgcacgacac aagcacaagc aagagtcaag gacgatcgat gggaagatcg ggcggagttc
     1381 gtcggtagga cgctgtttaa caaaacagtt ggtgtgattg gtgcaggaaa taccggaagc
     1441 ggagtaatcg aaattttgcg taacggtttt cgctgtgatg ttctagctta tgatccttac
     1501 aaatcagatt tatacatcga aagctttggt gcaaaaaaag tagaacttca agaattactg
     1561 gaacaatcag atatcatttg tttatgtgcg aatttgacag aagagaacta tcacatgatt
     1621 tctgataaag aagtcgatca gatgaaagaa aatgtttatc tatctaatag tgcaagaggc
     1681 gctctagttg atgaagaagc gatgattaat ggtctgaaaa gcggaaagat cgcaggatat
     1741 gccacagatg ttttagaaga agaaccggga cgtcaagatc atccgtattt agcgtttgaa
     1801 caagtagtga ttacgccaca tatatcggcc tacacaaggg aatgtttaga agcaatgggt
     1861 gaaaaatgtg tcagagatgt cgaacagatc agtcagcacc ttcttcctga acgttctgtc
     1921 cagacaaaga gcaactatat aaaaggatga tgaagaaaat ggtgaacggt ttaaaagtga
     1981 aaacaggccc tcaattttat ttatatgaag aaggtggtat ttcaaaagtt tctgatctct
     2041 tgaaatcata cggcgcgaaa agagtactgg tcacccacgg aacggtatca tgggaaaagg
     2101 cgctacctaa attagtattt ttgaatgacg aaacgattca atttttttat catcgttatt
     2161 ctggagaatg tagttatgct gaagccagac gaatagctac aatcatcaaa aaaatgaaat
     2221 cgatttcgta gttggcgttg gcggaggaaa actgaccgat ctagtgggtt atagtgccaa
     2281 tcttgcaaga atcgatttcg gagtcatccc tactttagct agtaattgtg ctccatggac
     2341 acctcttgct gtcatgtata aggagaatgg acaagcagaa gggaaaacag aacactttta
     2401 cagacaagct gcttttttta taacagatcc ccaattagtg attgattccc ctgttccata
     2461 tttcattgcc gggttagcag atacactagc aaaatggtat gaatctgagc tcatcttaga
     2521 acaagatttt ttgcaagatg aatcattttt gaagctagca caagatactg cgaagatctg
     2581 caaagaagag attttgaatc attctgctaa agcaatccaa gatatggcac aaagaaaact
     2641 gacatcggag ttcaaacagc tttcagagat tatctttgct gttgctggtt tagttggagg
     2701 attaggagat aaatacgcaa gaaatgcggc agcacatgct atgcatgacg ctatcagtaa
     2761 atatattccg gaaagccatc gttttctaca tggagaaaaa gtagcgtatg ggattttcta
     2821 tcaactggca ctagaaggtc gctgggaaaa aatagacgag ttatatcctt tgtatcggga
     2881 attagaactg ccggtttctc tagaacaaat gggattattt ccgaaagata aacagataat
     2941 agataaaatg gctgaattta ttgattcgaa agagaaagtg catttgattc ctatagaggt
     3001 aacacagaaa tcactgatac agtcaatgat ggaactggaa ggttatatca gaaagatctg
     3061 aaggaggagg acacatggaa acattaagtg tagtacaaag tttgttgatt gctttatggg
     3121 tagccgcggt tatgtcccgc tggttaggtg gaggagccac gttgacctta cgtttttctc
     3181 ctttgatgac tggattagtc gtcgggttga tcatggggga agttgcacaa gcgatgattg
     3241 ttacagccgc tttgcaaatg atttatatgg gggttttttc tccaggagga tcaatgccag
     3301 ctgaaccatc tattgcagca gctatcgcag taccagtcgc attattaggg gatctgtcgc
     3361 cagaagcagc gattgccgtt gcggtgccag tcggattgct cggaagttac ttgtatcagt
     3421 ttcgtttttt catcaatact tttttaggta aatatacaga caaagctgta gaagatttga
     3481 atacaaaagc tatggcccga tcaattattc tttatccaac ggttgcctca tttttattat
     3541 tcgttccgct tgttttcatt gctttatatt taggggcgcc attgatcgct gatgtaatca
     3601 aagctttaga gggaacagtc gttatccaca ttcttgaagt agtaggtgga gggttagcgg
     3661 caatcggtat cgcgacaact gtatacgtta tcggtcgaaa agattatctg gtctttttct
     3721 tccttgctta ttttatgagt gttgttttga aatctttaga tattacgatg gttacttatg
     3781 ccatttttgg gattattatc gctttgatct ttgtccagtc gcaaaaaggg aaacaagtac
     3841 agcctgccac aagcaataac aattcagcat cttttgatga cgaagatgac tatgatgacg
     3901 gattttaatt taggaggaat gggaaatggc tgaaataatg gataatcaaa caggtgctcc
     3961 tgaagaaatc acgaaaaaag atgtaacaaa agcctatctg agatggcatt ttgcaaacga
     4021 aattcctcac tcttttgaac gttacttggc gccatcacta ctatacggaa tgatgccaat
     4081 cttgaaaaaa ctttataaag atgaagactc tttaaaagca gcatataaac ggcagttact
     4141 gttcttcaac actcaattaa gctggggtgg cggtgtgatt actggcctaa tgtcttctat
     4201 ggaacagcaa agagcagaag aagagtatga agaaaaagag atcttgatgc aggatgactt
     4261 gatgtataac acgaaagcgg gattgatggg ggcactagca ggaatcggag atgcaatcga
     4321 ttcaggaacc gtccaatata tttttatcgc aatcgcggta ccttgggcac aacagggaag
     4381 tcctttaggc gcactttttc cttttatctg ctttgggttg tatcaggttt tactaggggt
     4441 atttttcgca agacaagctt tcactatggg ccgtaatgct acaggcctaa tgcaaaacac
     4501 tggtgttcag acagcgattg aaatgctatc agttttaggg ttgtttatga tgggggtgct
     4561 tgcgggaaac tatgtaaaag tagaatcttc attgaaattt gcgatatccg gacgtgagtt
     4621 tgttatccag gaaattcttg atcaaatcgt gccagggata ttacctttag ctgtcgtaat
     4681 gggtgtgtac ttgttctata cgaaaaaagg attgaaagtc acacaagcat tattatggct
     4741 gactggaata ttaattgtgc tagcaggaat cggtatttta taaaaagaag ggaacgtgaa
     4801 taagatgggt gtagtcaatt tagcgcgtgt ggatgagcgt ttgatccatg ggcaagtaat
     4861 ggtaacgtta tctcaaaaaa gtggagtgaa ttccattttt gttgtagacg aagttgtagc
     4921 aaaagataaa tttatgagag atctttacaa aaatgcagga agccgtacag gacaaaaaac
     4981 aattgtcatt acaccagaga aagctaaatt ctattgggat gaatatcaat ttaaagaata
     5041 caattgtatt ttgatcgcaa aaacagtcca aacgatttac gacttagtaa aacacggaat
     5101 ccccatggaa gaattgaata ttggagggat tgctcaaaaa aatcctgata cagatctttt
     5161 agtgacgaaa tctgtttatt taaataaatc agatgctgaa aaattgaaag aaatgaatga
     5221 acaatatggc gtaaagaata tttattttca agccactcca tctgcaccta aaacaggatt
     5281 aaaagatgta ttgaacaagt ttgatttgtc ataaacaaat gcttagaaaa aagataaaga
     5341 gggcgaaaaa atgaagaaga acgagctgtt tcgtgattgg gaatttcgtt atcgctatat
     5401 ttaccgtaag cgccgtacaa aaaagagtaa acagcgtttt ctttcagcat tagtatcaga
     5461 tatttacagt atgagaacag atgtgacagt cattgcttac gatacgctag cctaccgatc
     5521 aaaaaatatt tatgttggag atatcgaaaa agcagagaaa gttatctgta cttattacga
     5581 tacacccgtt catgcattag gaagttattt catgtttgat tggaaagacc aaaggaaaaa
     5641 aacaatctac tctatattat tgtccttcat tttgttgttc agtttaggtt ggtggggaat
     5701 gatgatatat aacaaaaatc ctcatcacgt attcgatctg ctatccgtat aaacaggtat
     5761 cactgtacta gcatttggga gctacttttt cttattggga aaagcagctc gcggatggcc
     5821 tagcagacaa acttttattc gaaatacttc atccatatta acgatgctag aaatgatccg
     5881 tacgattgat gatccgagtg tagcgtatgc gtttgttgat gaaggctgtt atggagaaaa
     5941 gggcttagac agcgtgagat cgggtatgaa aaaagaggct attctttttt atctagactc
     6001 tgttggggca gatacaccgc tacagttttc gggaaattat ttttcaaata aagaacagtg
     6061 gctgaaacaa gttgataagt tgaaagaaaa aaacgtcaat tatattttta gtgcaagaaa
     6121 aaagcaagcg cagttcttct atttgaccaa aacagattta cgagggaaaa catttaattg
     6181 gcaaaatgcc aatcagatta ttgctctttt tcgataagta aaaagtgcaa aacaaggagt
     6241 gagaagacta atgttggaaa tcatgatcgt tacacatggt aagttgagcg aaggactgaa
     6301 agatgcggcg gaagtaattg tcgggacatc gagccatatt gaaacaatgt gcttagagtc
     6361 tggggaggac atccaaacat tcggagagaa ggtcaaagaa aaattaacta tgatcaacac
     6421 agcagaaccc atgctagtat ttgttgatct aattagcgca agtccgtaca atcaagcgct
     6481 cttggcagtc aatgaactga ctgaagaaaa gaaagcagcc acttatgtca tagggggcgt
     6541 gaatctgcca atgttgttag aagcaatcaa tcatcagatg cttcacacac cgatagaaga
     6601 agcggtggaa caaattgtca aacaaggaaa agataattta actgtttggc atgcttcagc
     6661 ggaagaaaaa aaattagatg aggacgattt ttagaaggaa ggctgaaaag atgaagtggg
     6721 gatttagatg gtatggtgaa aaaggggatt cgatcccatt aaaatatgtt cgccaaatac
     6781 cgggaataaa tgggataatt ggaactttgc tgactaaaat gcctggagat gtttgggaga
     6841 tttcagaaat tgaggagttg aaagcatctg ttgagagcca aggactggaa ctgcttggaa
     6901 ttgaaagtgt agcgatccac gatgcaatca aggcagggac agatgaacga gattactata
     6961 ttgataacta tatacgaaca atcaaaaact tgtctcgatg tggggttcga ttgatttgtt
     7021 atagcttcaa accaattttt ggatgggcga aaactgattt gtttaatgaa aacaacgatg
     7081 gaagctattc tcttttatac gatcagaaaa tcgtcgatca gatggagcca ggagaaatgt
     7141 atcaattgat acacagccag tcaaagggat tcaaattgcc gggttgggaa gaagaacggt
     7201 tgaaaaaatt cgctcagctg gaaaaactgt atgaaggaat gaccgaagaa gaattatttg
     7261 aaaatctgac ttatttttta gaaaaagtga ttccagtgtg cgaaaaagca gatgtaaaaa
     7321 tggctatcca tccagatgat ccgccatggg aactttttgg ttttcctaga gtgacgaaaa
     7381 atcttggcga cttgaagaaa attctaaatg cagtagattc tccatataat ggactaacgc
     7441 tgtgcacagg atctttaggg gcaaatccgg aaaacgattt agttgaaatc atccatgagg
     7501 taggttcgcg catccatttt gtccacttca gaaacgtgga gtttttagga gaaagaaagt
     7561 tcaaagaaac ggcacatccc tctacagaag gctcccttga tatgtatcat attatgaaag
     7621 cgttggtgca agaagggttc gacggtccta tacgccctga tcatggtaga accgtgtggg
     7681 gtgaagtggc tatgcctgga tatggcctgt atgatcgtgc aatgggactc acttacatgc
     7741 aaggtctata tgaggcgata agtaaggaaa aaccactggg agagcattat gaataaaatc
     7801 aagctcttca tctttgatat ggatggcctt ttattagaaa ctggacgttt agcttatcgt
     7861 gcttatgtaa aatcagcaca aaagtatgat tatgaaatgc gtaaggaagt ctattattta
     7921 ctaactggcc aaacagaaat ggcgataaga gaacaaatgg gcattttgta cggagaagat
     7981 gttccatata tcaaatggcg agaagcaatc aatcaatata aagaaaaaat cgtgaaagaa
     8041 gataagagag tatatacgaa aaaaggagca gaagaaattt tatcttttgc aaaagaaaga
     8101 ggaatccata caatcgtggc ttcgtctaat acacgggtaa aagtagaaat gtatttaaaa
     8161 atggaaaatc tatatgcctt gtttgatcaa atcatttcag gggatgatgt aaaaaaagga
     8221 aagccggaac cagagatctt tttgaaagct tgttcaaaaa tgaatattcc tccaagtgaa
     8281 gcacttgtat ttgaagactc gattgcaggg atcgaagcag caaggcgagc gggcattttg
     8341 tcttttctca tcaaagatca tttgataggg ttgcccgatc ataatgggaa gcataagttg
     8401 aaagtagatg taagtttata tgaatccaat aaagcagact atgaatttta tgacctgcat
     8461 caagcaaaac gatttttaga aagtaaaggg ttgtatctct aataaagagg actattttct
     8521 agtcctcttt atttattgtc ctgcacgact gagggaacag atgaaaaaga agtaattttt
     8581 tattttgaag tatctacctt atttgtagtg aacaatttag aacaaacaca aaacgcatct
     8641 actgttatct accagtagat gcgtttaaag agaagaacga gaatcgtcca tatgagggtt
     8701 tccactcctt atgcagattt ttttaattct tgcactgctt gttcgatcgt aacacctgtc
     8761 gctacatgat tggtattttc tttgtcaaaa acgacaaata gattcaaatc tgtatccaag
     8821 gttactcgat attgtatatc tttgttatag aatgtcatag ccattctcct ttctttaaat
     8881 acttgctgaa aggcaacgaa cgcgttgata acgaaattcc atttataagt ataccaccaa
     8941 ttgaaaggtt ttcatagtta agaaatttta aagtcaaaag ttgcagataa aagcaaataa
     9001 acaagaaaac aaaaagtgaa tcaatcgcgg ttattcaact ttttcttcga ttcgaagaca
     9061 atagaagaca atgaatttta tatttcattg cattatcctt gtgttattag aaaaagcatg
     9121 atatattaaa tgagtaatct attttgaaac gtaatttgag cgatatatct acatagataa
     9181 aactcctttt gcctatcaaa tatttattgc aacgaaaaaa cgtacattga tacgtatcag
     9241 gaggaattta tttatgaata acggtacagt aaaatggttc aacgcagaca aaggttttgg
     9301 ctttatcact ggtgaagatg gaaatgatgt atttgcacat ttttcagcta tccaaggtga
     9361 cggcttcaaa actttagaag aaggccaagc agtgtcttac gatgttgaag atggtcaacg
     9421 tggccctcaa gcaacaaaca ttgttaaagc ttaataaaaa ttgactttta accgtctttt
     9481 cgaaagaaaa gacggttttt ttgtacgaaa aaatt
//
LOCUS       DAFLWC010000100         9470 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.103, whole genome shotgun sequence.
ACCESSION   DAFLWC010000100 DAFLWC010000000
VERSION     DAFLWC010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9470
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.103"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(130..777)
                     /locus_tag="L1V17_002508"
     CDS             complement(130..777)
                     /locus_tag="L1V17_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HBN1237221.1"
                     /translation="MEQTIKPYQYFFIKREVDQLLNAYSSVNDPKTVQTVQALAAEKI
                     RDILEHELPEIDTFLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(1056..1559)
                     /locus_tag="L1V17_002509"
     CDS             complement(1056..1559)
                     /locus_tag="L1V17_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBN1237222.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(1682..2446)
                     /locus_tag="L1V17_002510"
     CDS             complement(1682..2446)
                     /locus_tag="L1V17_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBN1237223.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     NAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLADVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            2553..2828
                     /locus_tag="L1V17_002511"
     CDS             2553..2828
                     /locus_tag="L1V17_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HBN1237224.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            3505..4455
                     /gene="yidC"
                     /locus_tag="L1V17_002512"
     CDS             3505..4455
                     /gene="yidC"
                     /locus_tag="L1V17_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBN1237225.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPANNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(4634..5608)
                     /gene="lacD"
                     /locus_tag="L1V17_002513"
     CDS             complement(4634..5608)
                     /gene="lacD"
                     /locus_tag="L1V17_002513"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBN1237226.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPEYGLPAAALREKECGLLLAYEKTGYDTKIPGR
                     LPDLLNIWSVKRLKEAGADACKFLLYYDVDEPAEINVQKQIVIERIGSECEAEGIPFF
                     LEILSYDATIGDPSSLAYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QETCYSQAEASAYFYEQSKVTEQPFIFLSAGVNATLFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLEETATPVYVDR"
     gene            complement(5605..6063)
                     /locus_tag="L1V17_002514"
     CDS             complement(5605..6063)
                     /locus_tag="L1V17_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1237227.1"
                     /translation="MTIIHEENIFLQQPLDSQEEAFKFLAKQTFCLGIALDEKEVYQK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSMIIATLNKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRKAKSKTEIATILTKEIGEDL"
     gene            complement(6060..7523)
                     /locus_tag="L1V17_002515"
     CDS             complement(6060..7523)
                     /locus_tag="L1V17_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1237228.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGIKIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFAGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTVLADNEAADTLEPEAMSGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSFDPDHAQYNATAAMVKAVGDAAMGMMVPVLAAYIAEGIAKRPGLVVGFVGGIVAM
                     NGGTGFLGGILAGFLAGYFILFLQKLLTILPKQLDGLKAIFLYPVIGVAFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEHSNPLVLGVIVGCMCAFDMGGPVNKAAYVTGTALLAQGN
                     TTFMAGVSAACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKMDNKAANRTVIEKGRAGDLS"
     gene            complement(7505..8455)
                     /gene="pfkB"
                     /locus_tag="L1V17_002516"
     CDS             complement(7505..8455)
                     /gene="pfkB"
                     /locus_tag="L1V17_002516"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBN1237229.1"
                     /translation="MSIYTCTMNLAIDLFIETEEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQQKQIQTEFIEVPGMTRINVFTQVNQTGEE
                     YKLVNQGPKIPQTAVHNFLNQIRALQAEDYLCVSGSLPRGLSPKVLIEISRICQEKGI
                     HLIIDSSDQEAMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVELGAENV
                     LLSLGEKGAILFTKDRVFRGNSPKGKVVNTACAGDTMLGAFLAGYMNRRPLDETLRKS
                     IAAGSSTAFRKGLTDFLDVEELSKQIKIKEERFETWENIN"
     gene            8598..9347
                     /locus_tag="L1V17_002517"
     CDS             8598..9347
                     /locus_tag="L1V17_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBN1237230.1"
                     /translation="MDHKLSETEQYLWNFIEHHILEIPNYSIVKLSEQANVSTATIVR
                     TMKKKGYEGFTSFKHHLKEGENKNINFSFLDKVDKGIRRAILKNEQEVVRTINMLEIG
                     NIEDAIQRIKFADRVFVFARGFSEMIGQEMLVKLQLTGKNCQMHTDPEIIKSISRKLT
                     KKDSVIFVSLNGETKELVTAAKNCYDAEIGSILVTANHSSTLKDYCEINLVGFKSEGS
                     YFPDYEVRSRLPLQIIARILLDAYVLRMGEN"
BASE COUNT         2818 a         2002 c         1641 g         3009 t
ORIGIN      
        1 aaagaaaggg gctatcccca gactttagta ggcgtcatta gctatctttc gttagcattt
       61 aaaggcgaac accatcacct attcacttcc attaaaagat agcatatttt tctgtaaaaa
      121 acaataaaat tatcgttctt tctttacacg ttcagcaaat tcatagaaag gagccaattt
      181 cgttaactgt tgattacatt ggtcactatc atgacaaata taattcccct ttttcgtata
      241 cgtgccatca gaacctgctt tcgttgtaga aagaaaaagc gacacattcg atgttttctg
      301 acagattgca cagattccct tatttatcgt tggtgataaa gtaccgctaa tcccttttaa
      361 tttttcatct tcgtaataga ccatgaattt tttctgcgta cctggatcat tccagccgat
      421 gtacgtatgt tcttgcaagt cgatttcatt ccaagctggt tgtttgagtt ttttcacttt
      481 tcggaataat ttctcgattt gtggtttgct aggctgcata aacggctgga cgatttgctt
      541 cagctcctcc aatgctcttt ctgcttgcgc ttttgtcagt tttacgtcta aaactgtcgt
      601 taaaaatgta tcgatttctg gcagttcgtg ttctaatatg tctcgaatct tttcagctgc
      661 tagtgcctga actgtttgta ccgtttttgg atcattgaca gatgagtacg catttaataa
      721 ctgatctact tctcttttta taaaaaaata ttggtatggt tttattgttt gttccatgat
      781 tttaaagtcc tttcttctaa ccaaagtgca tactttgtag aaaaaagtga tcttctgcaa
      841 agtatgtgtt acctgaagat cccggactct tttaaataag atacgttttg catcttatca
      901 tcaccccctt taatgttcat tcttctatgt acatgattca ttcgataaat aaaagtaaac
      961 cgtatcttga acagatagtc aactgcaaac agaaaaaacc gagaaaatca gccagatttt
     1021 ctcggaatat agtctattat tattggtttt acctattaaa tcgaggattc tttcccaaag
     1081 taacgttgcc atctcttacg catacttgca gacatgggct gagccgcttc tttgactgcg
     1141 cagtatttgt ccacgaatgt cacaatatat ccttctttat acttaggcgg tgcgatcgtt
     1201 gcaccccaca tgtgcttcaa aatgatatct cgctcaagat ccgacaaatc ggtgattttt
     1261 tctgcattct ttacagcaat tcttggatgg atatacgcat gtgtcccctc gtcaaatttc
     1321 gtcgtacgcc aatcatagta gaacagatca tgcaaaagtc cagcacgcgc tgttgcttta
     1381 gcattgccac cccatttttt tgcgagcaga taactatagt aagaaacact gatggaatgc
     1441 tccaaacgag tggaatgaac atgctgtgtg taattcgcta attttttcac tgcttctgtt
     1501 tctaaaagat cttgtacata agacatatat tcttcgtctt cacgccattt ttctgtcata
     1561 attatcgatc tgccaccttt ttgaatttca ttttcttctg aaattgatct aagtatacca
     1621 ccagtgttcg gattattcta gtcgctctag ataaaatagc taaagcttaa tagttcctta
     1681 atcataaaga aaaatgataa agaacgatcc ctgctgcgac tccgacattc aatgattccg
     1741 catttccttt cattgggata tatacgttct gatcagtcaa agacaagatt tcctgactta
     1801 ctccctgacc ttcgtttccc atgattatag cgaaatcctc tgttttttct actttgtcta
     1861 atgcatgtgc ttcttcattt aattctgtac cgtacaccgt aaaccctttg cctttcatta
     1921 cagggattac atctgccaaa tctttttgta acacaggcaa atgataattg cttccctgca
     1981 tgcttcgcag cacctttgta ctataaatat ctgccgttcc tttacctaat aaaacaccag
     2041 ccataccaaa cgcatctgcc gtacggatca tcgttcccac atttccagga tcctgtacat
     2101 tatctagtaa aagccagcct cctgaaaaat ctggcgtatc ttcagatgtt aacgtcatca
     2161 ctgctaagat cccttgcggt gtaggtagat ctgacatagc ggtcatgacc tcatctgaaa
     2221 ctagaaaagt agaaatctct ttgtttacag ccagccagtc tccccattct ttcatacctc
     2281 tctgtgtcac aaaaagttct tttatttctg cattagacga cgcagcttct tcgatcagat
     2341 ggaacccttc caaaagatat tctgcctttt cttctctgta tttcttttta tgtagttttt
     2401 ttaattcttt gattcttgga ttttttgctg attggatctc tttcacattc ctcacctcaa
     2461 ctgattatat catggaatag gtgcttgagc ttgtttcatc ctaaaaaaat cggtatcatt
     2521 gatttataaa acaggaaaga aaggtgacga acatgcgcaa agttaaaatg aatgtccaag
     2581 gacgtgtcca gggcgtggga tttcgctata tgaccaagat ggttgctgat cagttaggcg
     2641 tgaccggaac ggtaaaaaac gaagacgacg gctcagtcac aatcgaagca atcggaaatg
     2701 acgacatcat ccaaaaattt atcgaagaag tcaagaagtc tccgagccca agtggacgag
     2761 tgcagtatgt ggatgtccaa gaagatccga tgattgagga acgaaagaaa tttgatgtag
     2821 tgggataagg ttgtgaaaag gtcgcttagt tttgagtatt aaggaaaatt ttgtgaaaat
     2881 ggctttccac atttttgcat aaatttgact taataccgag aaactgactt ttgaacaccg
     2941 tcgataaggt tgtttttgaa gcgctttgcc tcgagtatta aggagaaaca ttttcaaaat
     3001 agcttctcat attttgaaat gtaatgactt aataccgaga ggcagctgat aaaacaccgt
     3061 caataaggtt gtgaaaaagc tggtctgcat caagcattaa ggactggttg tgataaatag
     3121 ctctccatat ttttcaacag gctggactta atgccgtaga tgcaagcttt tgaacaccgt
     3181 cgataaggtt gtttttgagg cgctttgcct caagtattaa agacaggtag taaaaaagct
     3241 gatctataac ttgcaatgaa tttgcttaac ccatattttc cagacagaac aaaaaagttt
     3301 ttagtttttt aaataagaaa gaaacacttg gaatcactct tttctttcta agtatttctt
     3361 tcttgatttt ttgtcttttt tcaaaatttt tcgctacgaa aaagaacgaa tatttatatg
     3421 aaatttctat gaagttgatt gaattccatg cgctttttta gtatagttaa gtttgtgtaa
     3481 aaattataga agaggaagta ttctatgaat aaatggaaaa actggttatt gggatccgga
     3541 cttgtcagta tcctgctctt tttatctggc tgtgtgcgga tggattcaaa cggaaaccct
     3601 gacacttcag gaatcgttta tcgagtactc gtccatccta tgggccaagc gattacatat
     3661 ctagttgaga atttcaattg gtcttacggc tgggcagtta ttgcaatgac tgtgatcgtt
     3721 cgtatcatca tcttgccact aggtatcagt caatcgaaaa aaacaatgat ccaatctgaa
     3781 aaaatgcaag cgttaaaacc acaagttgaa gcagcacagc aaaagctaaa agctgcaaca
     3841 acacgtgaag aacaaatggc agcacaagca gaaatgcagc aagtatatcg cgaaaatgga
     3901 ttgagtatga ccggcggaat cggctgtctg cctctattga tccaaatgcc gatcttctct
     3961 gccttgtatt ttacggcacg ctacacagaa ggtatccggg aatcatcttt ttacggcatc
     4021 gatctaggct caccaagtat ggtgcttgtg gccatcgcag gggtcgctta tctgcttcaa
     4081 ggatatattt caacaatcgg tattcctgaa gaacagaaaa agacgatgcg tacgatgctg
     4141 atcgtctctc ctgctatgat cgtcttcatg tcaatcagtg cgccagccgg tgttacactt
     4201 tactgggtag tcggtggtgt gttcagctgt ctgcaaacat tcatcacaaa cgttatgatg
     4261 aaaccacgtt tgaaagcaca agtggcagaa gagttgaaac aaaacccgcc aaaacaagtc
     4321 gtcactccaa gaaaagacgt gacagaatca gcaaagccag ctaacaacaa acaagcaaca
     4381 aaacaaatca aacaaccaaa aaacagtaca aacaacaaag gccgcaacgc aggaaagcag
     4441 cagaagcgga agtagatagt aaataagagt gtaataaaaa ttcattaaca gttttagcaa
     4501 ttaaaaatat cgaccaagat ttttgaaaaa gaaatctggt cgatattttt atttaagtga
     4561 atgtttaatt tgaatcatcg attgatcgct atctaattgc agcagcatct ttttatgaag
     4621 aaacaacttt ttcttatcta tcaacgtaga caggtgttgc tgtttcttct aatagtgtac
     4681 ttaattcttt aatattttgt tttccttctt ctaacatcca actactcgct ttttcttcgc
     4741 cttcggtaac aaaaggtgcc actcccttcg cccatgttgc tcgcccacat aagacaccat
     4801 tgaatgtcga acctgattgt tttgcaaaac gtaatgtatc ttgaaatagc gtagcattga
     4861 ctcccgcact taaaaaaata aacggttgtt cagtcacttt cgattgttca tagaaatacg
     4921 cggatgcctc tgcttgacta taacaagtct cttgcccata tccttccaca aatctcatat
     4981 tcactggcac ttctactttc aatacatcca cttgataacg ttcttttgaa aattctcgca
     5041 tggcttcaat aactttatgt ggttttactt ttgcataggc aagagaagac ggatcgccaa
     5101 tagttgcatc ataagaaaga atctctaaaa agaaaggtat gccttctgct tcgcattctg
     5161 aaccaatccg ttctataact atttgttttt gcacattaat ctctgctggt tcatcaacgt
     5221 catagtacaa taaaaattta caagcatccg caccagcttc ttttaacctt ttcaccgacc
     5281 aaatattcaa taaatcaggt aatcttcccg gtattttcgt atcatagccg gttttttcat
     5341 aagctagcag taagccacat tctttctctc gaagcgctgc tgcaggcagg ccgtattctg
     5401 gatcaagtaa aatagctgag gcatagggag tcaggtattg agaaaccatc tgtttaaatt
     5461 ggatgatgtc ttctgatgta gcttctttat attggttgat cattttcttc aaagcaccac
     5521 gctggtcgat tgctaatgcg ctaataattc cagcttcatc cgtcaatcgc ttcaaacgtt
     5581 cctgtttttc tatactcatc ttcttcatag atcttcacct atttctttag ttaatattgt
     5641 ggctatttct gtttttgatt ttgcttttct caactgttct gtaacctctt ttcgcatcaa
     5701 tgatcgtgca acgagagaca ataatttcaa atgagtcgtt cctgcttctg aatctggaat
     5761 aaataacgca aaaataaaat caactgactg tctatctaaa ctgttccatt caattccttt
     5821 gttcagtgtg gcgataatca tactaggttc gttgattgtt tgagacttcg catgagggat
     5881 agcaaaacct gacattattc ctgtagtccc ttctttttct ctttctagaa gtttttgata
     5941 tacttctttt tcgtcaagag cgatccctaa acagaatgtt tgctttgcta aaaacttaaa
     6001 tgcttcttct tgactatcca atggctgttg taaaaaaatg ttctcttcat gaatgattgt
     6061 catgataagt ctcctgctct tcctttttcg ataactgtac gatttgctgc tttattatcc
     6121 atcttcttgt ctttatcagt tactcttttc ttttggatta atcctagtat cactccacca
     6181 acgatcgaac caataagaat cgctgtaacc cattggattt ttcccgtcac tacaggtaac
     6241 actaaaaaac caccatgtgg tgctggaact tggacgccaa acaaataagt taagacagca
     6301 gcaattgatg agcctaacat catcgtgggt aacactcgga tcgggtcttt cgcagcaaac
     6361 ggaatagctc cttccgtaat atgagttgat cctaaaataa aattaaccaa acctgcatta
     6421 cgatcattgg tatcaaaata tttaccaaac aataaagtag caaaaccagt aatcaacggt
     6481 ggtgcaatac aagctgctga cacaccagcc ataaaagtcg tgtttccttg tgccaaaaga
     6541 gctgttcctg ttacatatgc cgccttatta accggtcctc ccatatcaaa cgcacacata
     6601 cagccaacaa tcacgccaag aacaagtgga ttcgaatgtt caaatccagc taaaaagctc
     6661 atcattcctt catttatagc cttcattgga cctgccagca aagacatcac gatgccaata
     6721 aatgctacac caataactgg atataagaag attgccttca agccatctag ttgtttaggt
     6781 aaaattgtca gtagcttttg caaaaataag ataaaataac ctgctaagaa cccagctaaa
     6841 atacctccta aaaatccagt accgccattc atggctacga ttccaccaac aaatccaacg
     6901 actaaccctg gacgtttcgc gatcccttct gcaatataag ctgctaaaac tggaaccatc
     6961 attcccattg ctgcatcgcc aactgctttt accattgccg ctgtagcatt gtattgtgca
     7021 tgatctggat caaaagaata gattccccaa acggcaaatg aaatagcaat caatactccg
     7081 ccagctacca cgaaaggcaa catatgagag acaccgttca ttaaattttt atagatgcta
     7141 cgaccaaaat tagcaccact catcgcttct ggttctaaag tatcagcagc ttcattatct
     7201 gctaagacag taccttttcc tgccaatgct tcgtcaatca gccgttgtgc atccttgatt
     7261 cctgtactga cagaaacatc aatgactcgt tttcccgcaa atctttctga atggacatct
     7321 ttatctgcgg caataatgac agcatctgcc tgtttgattt cttcagccgt taattcattt
     7381 tcgatcccaa tttgtccatg ggtctccact ttgatcttga tgcctttttt cctagctgct
     7441 tgttctaatg cctcttgcgc catgtaagta tgcgcaattc ctgtcggaca accggttgct
     7501 gcaattagtt gatattttcc catgtttcaa acctctcttc cttgattttg atttgtttac
     7561 ttaattcctc cacatccaaa aaatcagtca gtcctttacg aaaagcggtt gagctgcctg
     7621 ctgctatgct tttacgtaac gtttcatcaa gcggtcgtcg attcatatat cctgctaaaa
     7681 aagcgcctaa catggtatca cctgcacatg ctgtattgac aacttttcct tttggcgagt
     7741 ttcctcgaaa caccctgtct ttcgtaaaaa gaatcgctcc tttctcaccg agggataaca
     7801 aaacattttc tgcacctaac tctactagtc gttgtccata aacaaagtaa tcttcatctg
     7861 taaccatttt tcgtccgaac caagaagaaa gttcttcctc gttcggtttc agcaaaaacg
     7921 gtcgataggg taaacaatcc atggcttctt gatcactact atcaataatc aaatgaatcc
     7981 ccttttcctg acaaatccga ctgatttcta ttaaaacctt tggagacagc cctcttggta
     8041 aactcccaga aacacaaaga taatcttctg cttgtaatgc tcttatttga tttaaaaaat
     8101 tatggacagc tgtctgcggt attttaggtc cttgattcac taatttgtat tcttctcccg
     8161 tttgattgac ttgtgtaaat acattgatac gcgtcatacc aggcacttca ataaactctg
     8221 tttggatttg tttctgctgt aaatagtctt ctatatactt tcctgtaaac ccagcagaaa
     8281 aacctaatgc cgtacttggg aaatctagca tttttaatac tagtgacaca ttcacccctt
     8341 ttccgtttgc ctgaatgtca tcctcttttg tgcggtttac cataaaagga tgcatctcct
     8401 ctgtttcaat aaatagatca attgccaaat tcatcgtgca tgtgtagata gacataacca
     8461 acgacctcct tgactctatt atgaaatacg cgaaagagaa aatgttttct taatcgtccc
     8521 aacacaaaga aaacctttac atttataaac tcgtcgtgct attttttaac taacttttgg
     8581 tgaaagaagg aaagaatatg gatcacaaat taagtgaaac agaacagtac ctctggaact
     8641 ttatcgaaca ccacatccta gagatcccta actactccat cgtgaaacta agtgaacaag
     8701 caaatgtctc aacagccacc attgtgcgga caatgaaaaa gaaaggctat gaaggattta
     8761 cttcgtttaa gcaccatcta aaagaaggag aaaacaagaa catcaatttt tctttcttag
     8821 ataaagtaga caaaggtatc cgtcgagcca ttctaaaaaa tgaacaagaa gtggtacgta
     8881 cgatcaatat gttggaaatc ggaaatattg aggatgcaat acaaagaatc aaatttgctg
     8941 accgggtttt tgtctttgca cgaggatttt cagaaatgat tggtcaagag atgctcgtaa
     9001 aacttcaatt aacagggaaa aattgtcaaa tgcatactga tccagaaatc atcaaaagca
     9061 tcagtcggaa actaactaag aaagacagcg ttatttttgt ttctttgaac ggcgagacaa
     9121 aagaactcgt caccgccgca aagaattgct atgatgcaga gattggttcg attctagtta
     9181 cagccaatca ttcctctaca ctgaaagact attgcgagat caatctcgta ggtttcaaat
     9241 cagaaggttc ttatttccct gattatgaag tacggtcacg tttgcctctc cagattatag
     9301 cgagaatcct gcttgacgcc tatgtattgc gtatggggga gaattgaaaa gcagtttatt
     9361 atggttggtt acagtttaaa acatcacatt ttttattctt tatattgtat ggactcacgg
     9421 aaacttttta tgtataaagt tattcacaat ctataaagtt actttaaata
//
LOCUS       DAFLWC010000101         9307 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.104, whole genome shotgun sequence.
ACCESSION   DAFLWC010000101 DAFLWC010000000
VERSION     DAFLWC010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9307
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.104"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(38..706)
                     /locus_tag="L1V17_002518"
     CDS             complement(38..706)
                     /locus_tag="L1V17_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBN1237231.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            840..1127
                     /locus_tag="L1V17_002519"
     CDS             840..1127
                     /locus_tag="L1V17_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237232.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            1543..3081
                     /locus_tag="L1V17_002520"
     CDS             1543..3081
                     /locus_tag="L1V17_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HBN1237233.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            3078..4043
                     /locus_tag="L1V17_002521"
     CDS             3078..4043
                     /locus_tag="L1V17_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1237234.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            4030..5352
                     /locus_tag="L1V17_002522"
     CDS             4030..5352
                     /locus_tag="L1V17_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBN1237235.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      5415..5519
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            5593..6336
                     /locus_tag="L1V17_002523"
     CDS             5593..6336
                     /locus_tag="L1V17_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1237236.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            6351..7343
                     /locus_tag="L1V17_002524"
     CDS             6351..7343
                     /locus_tag="L1V17_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1237237.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            7355..8092
                     /locus_tag="L1V17_002525"
     CDS             7355..8092
                     /locus_tag="L1V17_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1237238.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            8082..8804
                     /locus_tag="L1V17_002526"
     CDS             8082..8804
                     /locus_tag="L1V17_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBN1237239.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(8888..>9307)
                     /locus_tag="L1V17_002527"
     CDS             complement(8888..>9307)
                     /locus_tag="L1V17_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HBN1237240.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         3049 a         1604 c         1966 g         2688 t
ORIGIN      
        1 atttctgtaa attaaataaa gtagtgaaaa ataagaatca gtgctctaac tgttcaagag
       61 gatcaagtgg ttcaaatgtt tctgtagtct gttttgcttc caattggggc aaaacagatc
      121 caatttccag atacttcact ttattcaatg tataagatag aatagaacag ctaagtaatg
      181 tatacagaaa atgtgtgaga tccaaataaa gcaaggagac aactaaaata ccaaaagtaa
      241 tcaagaaaag acttttgcca atcttaatat gaaaatattt ttcaatggct tgataaatga
      301 tatctgttcc gcctgtgctt ccgccgaatc gaaagacgag accgcaacca atgccagaaa
      361 gaatacctgt catcaaacta ttgatcagta gactatctac agcaaaatgt atatgaaggc
      421 tctcccataa atgtaaaaag aaaactagcg caaatgttcc gacgatcgtc cggagaaaag
      481 cgtgttttcc aaaaagaaac aatgagataa gcaataaagg taaattaaaa agcagtgaag
      541 tgacagaagg agcgaatcca aaaagattat gcaaaagcaa agcaatacca gtaaccccac
      601 catctgccag cttagatgga atattgattc ctgtcacagc taatccgtag attcctgcgc
      661 ctaaaatgat tccgcacaat tctgtaaata aatttaattt tttcatttct agcctctttt
      721 cttttgaaaa ttttcagcaa cttctttatt atactgactt atactcttac ttcaagagga
      781 aaatgaaaaa aaattatttt tggctgtttc tttttattta tcaaataagg agtggaaaaa
      841 tgcgagcagc agacttattg acaattctta caaaatcacc caaaaaaaca gagtatcaag
      901 gagttttttt ggctcaagaa caaaaactgg tgcctgtgac aatggtccag ataaataaag
      961 caaatcaatt tatcttttta tttgaacacg gcaaagcacc acttgctatg aaagacatct
     1021 ttcttttttt gatgaagaac cgtgagaaag ctgtttatta tcagtcaaaa gaagaactca
     1081 ttcctcttta tggagtgaaa gagatagaaa ataaagtggt gatataagta aaaataagaa
     1141 aacaagacgt ttatgatgtc aaaacaacca ttttttacat ttttggcaaa aaagtgtcat
     1201 gatacagtat aatattcgtt gaacaggcca ataaaggtgt tctcccccac gagatttcta
     1261 ctttattggc tgtttctttt tattaaaata aaagttgtgt gtgtaaaaaa gatatagctg
     1321 attccaagtg acaatttcgt atagattttt atggtattcg tagtgaaaaa acgagaacca
     1381 aaaagttgat ccgactttgt tgcttggatt ctttttttgt cagcatattt agaggtattt
     1441 ttttcttttt tttgttcgtg ctgtaaggtt aaggcaagac aagttagttg ggaaaaagga
     1501 aagaaatgtt tatacttaaa gaataacaga aaggaaggtc gcatgaataa ttttatacaa
     1561 acattaagtg aaagaaaagg cgagttgctg gaagctgcat ttcaacatct gtccatttct
     1621 ctcatttctt tgctgattgc agcactgatt gctattcctt tagcgatttg ggcagccaat
     1681 cataaaaaaa tggcagaagt cttattgcag atcacgggtg tgctccaaac gattccttca
     1741 cttgccttat taggtttact tatcccattt gtagggatcg gaactgttcc agcattgatt
     1801 gcacttgtta tttacgcttt gcttccgatt ttccaaaaca cgtatattgg tctagctgaa
     1861 attgacccgt ctattgaaga agcagcggta gcatttggta tgtccagaat gagacgcttg
     1921 ctgaaagtag agcttcccat cgcattacct gtcattatct caggtatccg aactgcctta
     1981 gttttaatca tcggtacggc tactttggca gcattgatcg gagcaggtgg attagggaca
     2041 tttattttgt taggtattga ccgaaataca cctgttttga cattgattgg tgcgatcagt
     2101 tctgccttgc ttgcaattat attcagcgga ctgattcgct ggttgcagca taagaaacct
     2161 cgatattcca tcattacttt agcagcagtg gtgtgtttat ttggcggcgt ttctttatat
     2221 cagtctgcct tgtttaaaaa tgaaaccatc acgattgctg gaaaattagg agcggaacct
     2281 gaaatcctga tccaaatgta taaagaattg attgaagaca acacaaaaac agaagttgaa
     2341 ttaaaaccga attttggcaa gacgagtttt ttgttcaatg cactggatca aggtcaaatc
     2401 gatatctatc ctgagttcac aggtactgtc ctagaaagct tggtgaaggt acctgaagca
     2461 atgaaaagtg ctgatttgac aaaagaaaaa acatatgacg aagcagaaga attattgaat
     2521 aagcaattcg atatgacatt attaaaacca atggcttacc aaaatacgta tgccttggca
     2581 gtcaagagat cttttgcgaa cgaacatcaa cttaaaaaga tttccgattt ggcagctatc
     2641 tctgatcaga tcaaagcggg attcacactg gaatttattg atcgttcaga tggatataaa
     2701 ggaatccaag aagcatatgg cttgaatttt tcaagtgtac aaagcatgga gccaagtttg
     2761 cgttaccaag caatcaataa tggagatgtc aatattgtgg atgcctattc cacagatagc
     2821 cagctcaagg agtacgatct agtgactcta gaagatgatc gagggttatt cccagcttat
     2881 caaggcgcac cgctgatgaa aaaagatttt gctaaagaac atcctgaaat cgttaaagca
     2941 ctgaataaat taagcggaaa aataacagag gatcaaatga ttgatatgaa ttaccaagtc
     3001 aatgtcgaaa agaaaaagcc gacagaagta gcacgaatct tcctgaaaaa tgaaggatta
     3061 gtaaaggagg aagatcagtg actaaattaa tcgagttcaa acatgtgcaa aaaaagtatg
     3121 atggaaagta tgtcatcgat gacctaaatc tggcaatcaa aaaaggagaa atctttgttt
     3181 tggttggtcc ttccggtagt ggaaaaacaa ctactttgaa aatgatcaat ggattatcta
     3241 aaccatcagc aggagacatc tacttcaaag gaaaatcgtt aaatgaatat aatctgcaga
     3301 aaatgcggtg gaatatggga tatgtgctgc agcaaatcgc tttgttcccg accatgacag
     3361 tcaagcaaaa tattgaagtc atccctgaaa tgttaggttg ggaaaagcag aaaagagcag
     3421 accgtgtaga tgaacttctt caaaaagttg gcttatctcc tgatatttat cgagatcgta
     3481 tgcctagaga gttgtctgga ggagaacagc aacggatcgg gatcatccga gctattgctg
     3541 caagcccaga tgtgattttg atggacgagc catttagcgc attagatccg atttcaagaa
     3601 actcattaca agaattggtt ttgtccttac acgaagaatt gggcacgacc atcgttttcg
     3661 ttacgcacaa tatggaagaa gcaatcaagc taggtgatcg tattgcattt atgaaggatg
     3721 gagaaattat ccaatgtgac acaccagagc agttattgat gaatcctaaa aacgactacg
     3781 ttcggcattt ctttgatgaa ccgaaacaga cgaaagagtg gcgagtagaa gatttagtcg
     3841 tcaatggata tttcttaaat gaaataccag aaaatgctcg tcaacaagtt tgctttgata
     3901 cgcctatgaa agaagtatat tcgcttcttt cggtgtatcc aagcattgtg atagtagaaa
     3961 agcaaagaag tattgggtcg ctgacaagta aagaaatctt tgctttttta agtcgagagg
     4021 aggaaggaaa tgaaaacata tgatgcaatc atcatcggtt caggtgtgag cggcttaagt
     4081 gctgcttatg gattgaaaga agcaggtaaa acagtactag tggtcgaaga agatctatgg
     4141 ggcgggactt gtcctaaccg tggatgtgat cctaaaaaag tcttgttaag tgcagtagag
     4201 gcacgtaatc gggtaaaaca attgagtgga aaaggtttta acgagatccc aactgccaac
     4261 tgggaagaac ttcaaaaatt caaacgaaca tttacggatc cagtcccaga aagccgaaaa
     4321 aaacaattag cagaagctga aatcgatcat ctttcaggaa ccgctcgttt tttggatgat
     4381 tcatctattg aagtcaacga agaagtcttc catgcggatt acttagtttt ggcaaccggg
     4441 caaagaccta cgatcttacc agtggaggga aaggaatact tgaaaactag tgcagacttt
     4501 ttatcattgc ctgtactgcc taaagaaatc atttttatcg gtggtggtta tattgctttt
     4561 gagctagcta cgattgccaa tgctgcaggg agcaaagtaa ccattgtcca tcataatcaa
     4621 cggccattaa aagaatttga ggcgtctttg gtagaggaag ccgtccatca aatggaagca
     4681 tctggcattc agtttgcttt tggtgttgaa acccaaaaga tcatttcaga aggtactcgc
     4741 tatcgtttag tcggaaaaga gacggaatta gtagcagata tgattttttg tgcgactggg
     4801 agacagccga atacagaatc tttagcactt gagcaagcga atatcgtctt tgataaacac
     4861 ggaattgcag tcaatgatta tctgcaaacg agcaatccaa aaatttttgc gtgtggagat
     4921 attgtttcaa ggaaaacccc aaaattgaca ccagtcgcca cttttgaagg aaattatgta
     4981 gctaagcgga taacggatgc aacaagcgaa cctatcaaat atccgattat acctacgatc
     5041 gtctacgcca gtcctaaact tgctgaagta ggagttacaa aaagtcacgc ctcttcgtca
     5101 gatcaagtgg tagagatgga tcttaccagt tggttcacct atcatcgtgt caatgaacca
     5161 gttgctaagg ctgaattgac ctttgaccag caaaattatt tgattggtgc tgcagtgatt
     5221 agcgagcaag cagacgaatt gatcgatgat ttgacactcg tcatcaatca aaaattgact
     5281 aaaaaagagt tggatagcta tatcatgggg tatccgacat tggcaagtga tctctcctat
     5341 ttattgaaat aatcagcatg ataactaaag cgcttgttgc tttttccttc ttgtgctaca
     5401 ctttaaaaaa tgaatacctg tttctgggga tgtcgtagac gacatgagag taagttgtga
     5461 acttagaccc attgaacctg tcagttaata ctggtgaagg gagaaacata gcagacgctt
     5521 gaagcgggtt actatgtcgt gcccatttca agcgtttttt gttattcata ttagaagaaa
     5581 ggaggtaaca aaatgaagaa aaatctttat ccagcagtca gtatggcatt cattttaatt
     5641 atttggcaga ttgttgtcat agtttggaaa atacctgcct ttattttacc cggacctgct
     5701 gctgtatttt ctgcattagc ggcagatgca caagtattac tttcccattc tgtcacgaca
     5761 ttaaatgaag cagtgcttgg tttggtaata gctagcgttc tttcttttat tactgccttg
     5821 gcaatggatt attggaagtt tttagaaatg tctttttatc cgttactagt gatttcacaa
     5881 atgttgccaa tcatggtgtt agggccatta cttaccctat ggtttggttt cggtatgctt
     5941 ccaaaagtga tccttgttgt cttgataagc tattttccga tcgtagtttc tttttcggat
     6001 acattgagga aagtatcaaa agagcaaatc atctttttga aaacgatggg ggcagataca
     6061 gggaagattt atcgaatata taaaatacca gcgggtttat ccggcttctt ttccggttta
     6121 aaagtggctg ctacttattg tgtcagcgga gcagtcgttg gagaatggct aagcgctcaa
     6181 gcaggcttag ggtattacat gatacgcgta aaaaacagct accagatcga taaagttttt
     6241 gctgcgatca tttgtgtcat tctattgagt ttattgctga atggcgcttg ttcattattg
     6301 aaaaaagggt attatcgtat gctttatatt ttttaagaga aggggatcaa atgaaaaaat
     6361 tatggctttt attaccgcta ctgttgcttt tatccgcttg tggcactgca aaagaaacaa
     6421 gtagcaaaca agaaataaag gatttgaaaa aagtgacact tgttttggat tatgtaccga
     6481 atactaatca tactggcatc tacctagcaa aagaaaaagg ctattataaa gaggctggtt
     6541 taaatgtcca aatcatcgaa ccaggagata attcgacaag tattggtcta gtaggtgcgg
     6601 acaaagcaca atttggtgta agttatcaag aagatgtcac ttatgctcac gcagatggac
     6661 agaatatacc agtcaaagca attgctacag tgatcaaaca taatacttct ggattcgcca
     6721 ccctatcaga cagtaacatc cattcaccaa aagattttga aggaaaaaca tatgcaggtt
     6781 ggcaaagtcc aagtgaagaa gctgtcttaa aagctgtgat ggaaaaagac ggcggggact
     6841 tttcaaaact gacaatggta ggaagcaatg gagaagggcc agaaagctta ggaaaatcct
     6901 cagatatcca atggtacttt gaaggttggg atatgatcaa agcaaaagaa gcgggtattg
     6961 aactaaacta tatcccattg aaagaattag atgaacggtt agattactat actccggtaa
     7021 ttattacgaa tgatcaactg atcaaaagtg atccagaatt ggtacagtct tttatggatg
     7081 ccacgaaaaa aggctatcag gaagctatta aggatccaaa tgacagtgct aaactgttgc
     7141 aaaaatatgc aaaagaaaat gatcggacgt ttttagaaga atcacaagca ttcttgtcaa
     7201 aaaattatac ggatgatcct gagaattggg gattgatgga agaaaaagtt tggcgcaatt
     7261 atacagcttt tatgcaggaa aacggattga tcaagcaaga tgtaccttcg caagaactat
     7321 tcactaatca gtttataaaa taggagtgat agatatgtca atccaaatca gccacttgaa
     7381 tgtagtcatt gaaaacctga aaatattaga agacatccat ttcactatcc ctaaagatac
     7441 ctttacatcg attgtcgcgc caagcggagc cggtaagtca acattgctga aaactttaac
     7501 aggagtccag cctatgactt ctggaacgat caaagtagac gatcaaaaag taactggtct
     7561 ccatacagca tttagttata tgccgcaaga agatatgtta cttccttggc tgagcgtcta
     7621 tcaaaacgtt acgttatatc aaaaaatcaa tcatctaaca atcaatgaag aacaagtaag
     7681 ggattatctg gatatctttg ggttaaacgg ctatgaacat tttttgccgg aacaattatc
     7741 tggcgggatg aagcagcgaa cggccttgtt acgaacaatc atgaatcctt cttcttactt
     7801 gcttcttgat gaaccatttg gagcgttaga tgctatgacc agagggcaga tgcaagactg
     7861 gatgttgaag ctgcctaaaa aagcaaagcg gactacttta cttgtgacgc atgatatcga
     7921 agaagcaatt tatttatcag acaggattct tgtgctttcc gcccgtccgg cacatgtgat
     7981 tgctgagatt caagtgcctg aaaaacgacg gtcacgtgaa tggctactgc agcaatcaga
     8041 gttgaagcaa acgatttatc agttattggc aggtgaatta gatgttaagt gatgctcatt
     8101 gtcatttaga tgggagtcag agtttagcac tccttcagca ggaacacacg attttgacga
     8161 tcatcaattg tgattcgcca gaagaatgga aggaaaacag acagcttgca gcaagtaaga
     8221 ctcaagcctt aagttacggt atccatcctt ggaaagcaga tagctatacg tttgaacaag
     8281 ttgagccttt tttgaaaaaa gcaaggatca tcggtgaaat agggttagat aatatttgga
     8341 cgaatgtacc gatgactaca caaaaaaaag tatttgagcg acagcttgct tttgcagcca
     8401 taaatgagaa acctgttgta ctgcacacaa aaggatgcga aaaagagatc ttaaattata
     8461 tccaagctta ccctaatcac tatttgatcc attggtattc ttctttggac tatcaacaag
     8521 actatattga tttaggctgt tatttcagca ttggtcttga tttgaaaaag aatccagcag
     8581 tctggcaact agctaaagca gtcccaatcg accacttact tattgaaacg gatggactac
     8641 atgcagcaga gtgggcttta ggggggattt tttcagaaaa agattatgtc tcactgcttg
     8701 aagaacagtt aaagacaatc gctgagatca aagagctatc agttgaagaa gttaaaaaaa
     8761 atacttatca aaacttggaa cgtttcatta gattaggtaa ataaaaaaga gatgtgacac
     8821 aactagtgtc gcacctcttt ttggctttct ttgtataaaa gtaaactgtt tgattaataa
     8881 atgaatctta gtaccaaccg tttgcttccc agaatgcttt cgccgcttcc caagaaccat
     8941 aacgtgaagt aacatattgt tctgctactc tttcttggtt tgcagcagag tagtcaccat
     9001 ttaagtaaga agaatctaat tggtaacgtc cgatgtaacg tccgttcgtt gctgtgtaag
     9061 aaccgcttga ttctttttgt gcgatccatt cttttgcaga gcttgtgctt gctggagtag
     9121 cagcagtttc tgttacagca ggagcaggtt gtgtttcagc aacaggcgct gcttgttttt
     9181 ccgtttgaac cgtttcttgt acaacaggtt gttcagcttg gactggtgct tcttgaacgg
     9241 ctgcttgagg ttcagcagct gcttgtgcag agccttctgt tgggattgtt aattgttgtc
     9301 ctgagta
//
LOCUS       DAFLWC010000102         9280 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.105, whole genome shotgun sequence.
ACCESSION   DAFLWC010000102 DAFLWC010000000
VERSION     DAFLWC010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9280
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.105"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..435
                     /locus_tag="L1V17_002528"
     CDS             <1..435
                     /locus_tag="L1V17_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HBN1237241.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(759..842)
                     /locus_tag="L1V17_002529"
     tRNA            complement(759..842)
                     /locus_tag="L1V17_002529"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(806..808),aa:Leu,seq:cag)
     gene            1370..1870
                     /locus_tag="L1V17_002530"
     CDS             1370..1870
                     /locus_tag="L1V17_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1237242.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            complement(2060..2404)
                     /locus_tag="L1V17_002531"
     CDS             complement(2060..2404)
                     /locus_tag="L1V17_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HBN1237243.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(2558..3478)
                     /locus_tag="L1V17_002532"
     CDS             complement(2558..3478)
                     /locus_tag="L1V17_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBN1237244.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            3665..4156
                     /locus_tag="L1V17_002533"
     CDS             3665..4156
                     /locus_tag="L1V17_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HBN1237245.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            complement(4180..6555)
                     /locus_tag="L1V17_002534"
     CDS             complement(4180..6555)
                     /locus_tag="L1V17_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HBN1237246.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            6881..7507
                     /locus_tag="L1V17_002535"
     CDS             6881..7507
                     /locus_tag="L1V17_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBN1237247.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            7530..8234
                     /locus_tag="L1V17_002536"
     CDS             7530..8234
                     /locus_tag="L1V17_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBN1237248.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            8426..9259
                     /locus_tag="L1V17_002537"
     CDS             8426..9259
                     /locus_tag="L1V17_002537"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBN1237249.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
BASE COUNT         2828 a         1791 c         1651 g         3010 t
ORIGIN      
        1 tactcaggac aacaattaac aatcccaaca gaaggctctg cacaagcagc tgctgaacct
       61 caagcagccg ttcaagaagc accagtccaa gctgaacctg ttcaagctga acaacctgtt
      121 gtacaagaaa cggttcaaac ggaaacacaa gcagcgcctg ttgctgaaac acaacctgct
      181 cctgctgtaa cagaaactgc tgctactcca gcaagtacaa gctctgcaaa agaatggatc
      241 gcacaaaaag aatcaagcgg ttcttacaca gcaacgaacg gacgttacat cggccgttac
      301 caattagatt cttcttactt aaatggtgac tactctgctg caaaccaaga aagagtagca
      361 gaacaatatg ttacttcacg ttatggttct tgggaagcgg cgaaagcatt ctgggaagca
      421 aacggttggt actaagattc attatttgaa cgtttaaaca cattcaaaat atagtaagag
      481 gtcatgcgat ttattctttc gcatgacctc tttttgagtt taagtttagt ctttattcct
      541 taactatcgt ttgccagtat ttcttgtatc agaatctata aatctactat ttgaatcaat
      601 ctattaggtt ttaaactgtc ccaccttcac acaaattttt tttgatttat ttgaatctgg
      661 ttccgttgtt taaaattttt cctatattct tttagataat atgttatttt ctttctcatc
      721 gctccaggtg taccttctct ttataaaaaa acaaattatg cggctaagaa gactcgaact
      781 tccacgaggt caccctcact agcgcctgaa gctagcgcgt ctgccaattc cgccatagcc
      841 gcatcacatc ttttagttta ggattacatg tgttttttgt caagaacata tttttgttct
      901 ttttcatttc tgtacgccct cccttatgcc atctacacaa ataattcatc cgagcaactc
      961 catcatctat tgagggttgg tgaaaaaatc tgttttatcc atatgatcga tttcaatgtt
     1021 aaacgaacga ctctgggatt agtaactatt ttattttttt cttcatttct tttttcctct
     1081 ttttctcgat tcagctatct tctttcattt ggatattgat tatttcttct gttgattact
     1141 atccttctgg aattctagac gctgaagtaa ttcacgtttt ctttcttcta gagatcataa
     1201 gtaacgaatg aacgaacttc aaataatttt tttattgtaa ttcatatttg tattgttcga
     1261 tgattcttaa tacgatatga cacaataaat aaaaataggc atggctattt acaacaatag
     1321 tgctatagta gaaaacaaat gaataaggtt acttaaagag gtgaatacga tgaaactgat
     1381 caaactatgg gaagcagatt taaagaaagc ttatcagcta caaactagct ttggaccaaa
     1441 tgagagtgga tttatcaaca atgcttatgg ctatacattt gctgaatttt tagattatgt
     1501 aaaaaaatgc gaaaaaacgt ctttaggaat cgatcttcct gagagttacg ttcccgcaac
     1561 cgtctttatt ttagaaagtg atgaacatga gtatgtagga atttttaatt tgcgccataa
     1621 actgaacgaa acattaagaa acggcgctgg ccatattggt tacggcatct cccctaatta
     1681 tcgtaaaaaa ggatatgcca cacaaggatt agcattagta ctacaagagg caaaaaaaat
     1741 cggcattgat gaggcacttt tgtctgtaaa taaaaaaaat cttggcagtc ttaaagcaca
     1801 acaaaaaaat ggggctgcga tttatcgtga agatgagaaa gaatactata cgaaaatcaa
     1861 actgatgtaa aaaagaagga ttccaaaagg aaagggattt gaatgtcctt tatcaataga
     1921 acacatttat ttaattaact tataatatag cagacaaaat tttataaaca aagaaacctt
     1981 ttatctcttt tcttctagaa aggataaaag gcttttttgt ttttcctatt tgcttctcat
     2041 agctagtcag ccaagatttc tatcgtatcc ccaacgcaat ccgtgcataa cggctcatct
     2101 tatctgtcgt ccatgctgga taccagacta gtttgacttc tgctttcgtt acttctggca
     2161 cttcttttaa tgcgtcatgg atagattctg ttaaaatatc tgctaatgga cagcccatag
     2221 ttgttagagt catcttaatg actgtttctc cattttcagg attgaattct atatcataaa
     2281 tcaagcctaa attgacgatg tcgattccta attcaggatc aatcaccatt tccaaggcag
     2341 caagaatacg ttctttgatt agttctattt cttgtccaga ccgttcttgg tttgcttcgc
     2401 tcatcgtacg acactcctta acacgatttt tatttatcat actctttttt tagctgcttg
     2461 taaatgagaa tttagaagta agattctcgt ttaaatttat aaaaatgttc ttattagatg
     2521 taatagatta aatttattct aaaataaacc tgattcctca ttttttttgt gaacgatttt
     2581 ttatttctgg caatacgcca gttgttcgat acattttttg ttcgttttca tttgcaaacc
     2641 ggccaaatac tgaatgagtt ggtaaaatat tgataaatgc atcgtcgtcg atttcatgaa
     2701 cgatctgatc aagatcatac atttcgtagc gggtgatgac catcatgatc atgttccctt
     2761 gtttttttga atagccaccg acagacggca gtaatgtcat tccacgtacc atccgttttg
     2821 ctagttcttc tgttacctct tctggcttga cggtaacgat cattgctgtt actttttgat
     2881 gactcgtgtg gatggcatca attacttgag tcattgcata aatggaaata atcgtataca
     2941 aggcactttc ccagttaaag aagaagcctg cgatgactac aatgatacca tttagaatca
     3001 gcatgtagtt tccgactgtt tttccagttg tttgtgaaag tacaagagag atgatatcca
     3061 tcccaccagt tgtaaagccc atttttaaag ataatcctac gccaagacct aataaaacac
     3121 cgcctactag ggcattcatc aaaatattat cagtgatctg tccgactgga agcagcatcg
     3181 tcatcaccga tacacataca acattcacaa aactaaggat cgttgctcgt tttcctactt
     3241 tgagaaaccc taatacaaac acagggatat tcaaaagaaa aataaatgtt cctgtgtcta
     3301 tcttgatatg aaaccattca tataaaagcg aggaaatgat ttgagcgatc ccattcatcc
     3361 ctgcagaaaa gacattggct ggaatcaaaa aataatttaa agcgaccgca gcggtcaatc
     3421 cggttatcaa aataaccact attttcttta atctttcatt tttatgatac gcagtcataa
     3481 ttttactcac aagcacctct cccctacttt ggtattccaa atgtaagaat aacagtttat
     3541 ctattaaaat aaaatacttc gaactcaaat gagaagaatt ttagcaaaca ggtaagaatc
     3601 tgccctaatc ctatgataag atagatgtat ggtaaatatt tatatgtata tcaggagggt
     3661 tcctatggca aaagatgcta gcttcgacat tgtatcagaa gtcaatacag aagaagtaaa
     3721 aaatgcgatt cagcaaacaa caaaagaatt gtccaatcgc tttgacttca aggattctac
     3781 agtagaaatc aaattagaga acagcaatct agttgtattg agcgatgatg atttcaaaat
     3841 cgaacagatc aaagatgtat tatttggtaa gctgatcaaa agaaatgtgc caatcaaaaa
     3901 tatccatttt tccgaatcag aacacgctct aggtggcaaa gctcgacaaa ctgccgattt
     3961 ggtcaacgga atcgatcgtg aaaacgcgaa gaaaatcact acagctatca aaaatgaaaa
     4021 actgaaagta aaagcacaaa tccaagaaga tcagattaga gtgacaggta agaaccgtga
     4081 tgatctacaa gctgtgattg ctttattacg taaacttgac ttaccaatcg agttgcaatt
     4141 cactaactat cgttaatcaa aaaacgaggc tgacgtctgt cattcctcgt ttttttgatt
     4201 tactgcttct tttgataacc aaaaacgctg tattccttct tccaattccc caacacttcg
     4261 tacttctctt gctgtttgcc aatgttgtgg gaataaacgt cgataagaaa aactagaaaa
     4321 tcgttgatct gccaatacaa cgattccttg atccgccatg ccacgaatca ctcgaccacc
     4381 agcttgcaag actttgttca ttccaggaag ctgataagcg taagcaaatc caaggtgttc
     4441 cttctcatca taatatgatt tgatcagttc ctgctcatga ttcatctgcg gcaaacctac
     4501 acctacgatc atactgccga tcaatcggtc ccctctcaaa tcgattcctt ctgaaaaaat
     4561 cccgccaagt acgcaaaatc caatcaatgt ttcagcggga tttgtttgaa attttgttaa
     4621 aaatcgttcg cgttcttcct cattcatgtc cgtttcttgg attagcacat tgctgtcggg
     4681 atattgctgt ctgaatgctt ccaccgcaag atctaaatat tgataagaag gaaagaaaac
     4741 gaaataattc ccgacctttc catcagcaaa agcatgaatc gtctctacta attttgccag
     4801 actgtgttcc ctttttcgat aagtcgtctc taggtaattt gcgatgaaaa cttgctggtt
     4861 tccttctggg aaaggactcg gcagtttgta agccagactt ttttgtcccc ccagtgtttc
     4921 ctgataataa gagagtggtg aaaaactagc agaaaaaaga atactgcttt ttcctttatc
     4981 caacgactgc tcaagaaaca agcttggatc aatacaaaac tcttttacta tcagatcgcg
     5041 atacgttttt tcgactgttg tttcgtagtg atcatcataa aattcactga ccttcaaaaa
     5101 atgaagcaaa tcaaaataat aaggaagcaa ttgttcttgt gatgggtgct caggaaattc
     5161 tgccagccat tctttaattt tttcgcttaa ttgataacct gcctttacta aagattcagc
     5221 cggtgctttt tgatgatgat aatcccaatg atcttctttt gctatttctc ggatcgaatc
     5281 aaattctttt aatagtttgt tgaaacggcg atgaagtttt ttgaattcct ttggtatagc
     5341 ttccttactt cgtttcgttt tttcataaga tagttctgcc gaatacatct ctcgggaacg
     5401 attcaccaaa ttatgtgctt cgtcaatcaa aaacagatag tcctcgtttt tttcatcttc
     5461 aaaaaaacgt cttaaataaa cagttggatc aaataaataa ttgtaatccc caatgattac
     5521 gtcacaccag atactgacat ctaatgatag ttcgaaagga caaagtgtat gctttcttgc
     5581 ataagtttcg atgacttcac gagtgatctg attctcatga ttcaaaagat cccataaacc
     5641 ttcattaatc cgattgtaat aaccattggc atatgggcac tgatctggat tacaggtcgt
     5701 ctcatctaaa aagcagatct tgtctttcgc cgtcaaagtg acacttttta cttcagctcc
     5761 tgtatctttt aatgctgtca tagcatcttc agctacttgt ctagttattg ttttagccgt
     5821 tagataaaag atcttttctc cctcttcttc ccctacagct ttcaaagcgg ggaataacgt
     5881 agagattgtt tttcctgttc cggtaggtgc ttctacaaac aatttctgtt tcgtacggat
     5941 cgttttataa gcagctaccg ctagttcacg ctgacctttc ctatactcat catgggggaa
     6001 tttcaaagcc atcaaagagg cattgcgtac agtgcgccag ttttcttgaa aaacaagcca
     6061 ttctttataa tcttcagtca gctttttaaa aaaagtttct aactgctctc ttgtctgatg
     6121 ttcaaccttt ctcgtgatca cttcttctgc cgtctggaag taagtcaatt gcagatttat
     6181 ttcttgtaaa tcatgttctt gactatagat ataggcatac acccttgctt gatgaaagaa
     6241 aagttccact tgttctggtt ctaaatcttc aaatcgtggt tcggaggttt tgatttcatc
     6301 tatataataa ataccgtctc ttttgaaaat accgtctgca cggccttcaa cgatcaggta
     6361 atattcatct aattgaactg ttgtttttaa aaagacttct ttttcatagt tttctcccgc
     6421 atctttttgg agcttgcggt ggattctcgc tccttctaat gcagtatggt tacttttttt
     6481 acgattgtcg atacttccac gtcgcaaaat aaattctact aagtgccgca cagatatttt
     6541 tgactgtttg atcatttcca ccacctcttt ctctctaaga ttacctgaaa aaacctagtt
     6601 tagcaaaaag agctctcttt ccaaacataa aaaaacaccc tgctgattag gcagggatat
     6661 aggatataga atttggattt ttggatgaat ctaatgtaac aaggacatat taaaatgcta
     6721 tgaaaactta ctttccttct ctttagaata tccaaatact tttcatatag tctgataatt
     6781 cagataagta aagagaaata agtacctgtt tttgtttcct agcaatgaat gcgttatact
     6841 aatggatgaa agaagttttg gctatcaagg aggaatgcac atgcatatcg aaagattaaa
     6901 aacaggaatg attgaagaaa actgttattt ggtctacaac gaagaagcac ttttgatcat
     6961 tgaccctgga gaagatgcgg aacgaatcaa acaagaaatc aaaaaaacaa accaacagcc
     7021 ggtagcgatt ttgcttaccc atactcacta cgatcatatc ggtgcagtgg aacctttacg
     7081 cgcgtattat caaatcccag tttatgtcag cccactagag caaaaatggc taggtgatcc
     7141 gattttgaat ctttctggac tcggtagaca tgatgatatt gctgatgtta ttgtctcgcc
     7201 tgcagaatat gaatttgaaa tgaaaactta tactttagga aacatgtctt ttcgcgtcgt
     7261 ccctacccca gggcattcta taggaagcgt cagctttatt tttgatgatt ttgtcgtttc
     7321 tggcgacgcc ctgtttagag gaagtatcgg tagaaccgat ctgtatacag ggaatttaga
     7381 acaattactt catagtattc ggacccagct gtttgtatta cctgatgaat ttgcagtcta
     7441 tccaggacat ggcgatgcaa cgacgattga acaggaaaaa aggacaaatc cttttttcaa
     7501 tcgttaaaac gacttaggag gagaataaaa tgacagaaac tacactttat atcgtacgac
     7561 acggaaaaac gatgttcaat acaattgaac gagtacaagg ctggtgtgat acacccctca
     7621 caaagcaagg acaagaaggc attcattatt taggtcgcgg gttaaaaaat gtcgactttt
     7681 catttgctta ttctagtgac agtggtcgtg caatcgaaac tgcccgtatt attctaggag
     7741 aacattctaa gggaaaagaa attccttatt ttattgaaaa aaggattaga gaatggtgtt
     7801 tcgggtctct tgaaggtgga tatgacatgg aaatgtgggg tgtgatccct cgtgtattga
     7861 attttaaaac atatgatgaa atgtttacca cagaagtttc ttttgaacaa attgctaatg
     7921 ctgtatacaa cttagatacc gctgggtggg cggaaactta tgaaacattg cgagaccgtg
     7981 tatggacagg atttgaagat atcgcccatc actgcgaaaa aaatggtggt ggaaatgttt
     8041 tagtcgtatc tcatggtttg acgatcgcct ttttgcttaa tctgatcgat cctaaacagc
     8101 ctgttcgtgc tgggctttta aatggcagcg taacaaaggt cacttatgca aacggtcgat
     8161 tttctatcca cggcatcaat gatacgtctt atatcgataa cgggaaaaca catagtcgcg
     8221 actcgtttct ataatgggga tattttaatt tttaccagag aatcataaaa ggcaaagtct
     8281 gaacgagggc tttgtcttct tttttctctt cgtgtactta tctgctttat ttctcaagtt
     8341 tttcttaata ttaaaaaaca gattgggttt ctcaaaaaat aacggtatac tataagatgt
     8401 atcttaattg ggaaggaagg aatttatgtt ttttgcaaat attatcaaag cagtgattct
     8461 cggtattatt gaaggaataa cggaatggct gcccatcagt agtactggtc atttgatcct
     8521 agcagatgaa ttcatcaaac tggatgccag ttcacaattt atgtcgatgt tcaatgtcgt
     8581 tatccaatta ggggcgatct tggctgtcgt cgttctttat tttcacaagt taaacccatt
     8641 ttctccaagt aaatcaacgg tagaaaaaaa agatacgtgg acactttggt ttaaagtgat
     8701 cgttgcttgc ataccagcca tcatcattgg tttgcctttg gatgattggt tagaagcaaa
     8761 tttccacaag ttcttaccag ttgccattgt tttgatcgtt tacggtattg cctttattat
     8821 tgtcgaaaaa cgcaacaaaa acaaaacacc tcgttggact tctctgaatg actttacgta
     8881 ccaagcagct cttcttgttg ggttattcca agtcttggca cttgttcccg gaacatcccg
     8941 ttctggcgca acgatcctag gatctatctt gattggtgct tcgcgttttg tcgctacaga
     9001 gttttcattt ttcttaggga ttcctgtcat gtttggcgca agcggcttga agatcgtcaa
     9061 atatttagct gaagggaatt cattcaaaat ggaagaaact gttgttcttc ttgtaggaac
     9121 attcgtatct tttgtggttt ccgtcttagc tatcaaattc ttactaagct atttgaagaa
     9181 aaacgacttt accgcttttg gctggtatcg tattatcctt ggtatcattt tgattggtta
     9241 ttggtttatt gcaatgtaga aaaaaccaga acacttctct
//
LOCUS       DAFLWC010000103         9048 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.106, whole genome shotgun sequence.
ACCESSION   DAFLWC010000103 DAFLWC010000000
VERSION     DAFLWC010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9048
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.106"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            700..2610
                     /gene="ltrA"
                     /locus_tag="L1V17_002538"
     CDS             700..2610
                     /gene="ltrA"
                     /locus_tag="L1V17_002538"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBN1237250.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            2714..2938
                     /locus_tag="L1V17_002539"
     CDS             2714..2938
                     /locus_tag="L1V17_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237251.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLNLFNRIVGA"
     gene            2951..3451
                     /locus_tag="L1V17_002540"
     CDS             2951..3451
                     /locus_tag="L1V17_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBN1237252.1"
                     /translation="MEQIRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELKGTPIGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCNDMSDVAYYLIVEAGDLGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFELM"
     gene            3548..5395
                     /locus_tag="L1V17_002541"
     CDS             3548..5395
                     /locus_tag="L1V17_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBN1237253.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            5398..6294
                     /locus_tag="L1V17_002542"
     CDS             5398..6294
                     /locus_tag="L1V17_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1237254.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNLYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            6344..6733
                     /locus_tag="L1V17_002543"
     CDS             6344..6733
                     /locus_tag="L1V17_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBN1237255.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            6720..>9048
                     /locus_tag="L1V17_002544"
     CDS             6720..>9048
                     /locus_tag="L1V17_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBN1237256.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTDALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLEN"
BASE COUNT         3197 a         1362 c         1908 g         2581 t
ORIGIN      
        1 aaaagctaag gcactaataa aagaacgaaa aagtttggtt attaggagaa ctgataatct
       61 gacaggtgga atgatgaagt aacgctctga aacgcctgcc ctgagcctcc gacaagcatt
      121 gtatgaggaa actcagaatg tttgaagctc ggtaaagacg gctgaaagat accgtaatag
      181 ttgatgaaca tatatcttct atcgaaaact atccagaggt gggtagcgta tccaacaggt
      241 cgggggtcta taaaatatct atggttagaa tgttctataa ggaactgacg aaacagcgaa
      301 tgtacgggtc taaatttgaa ctttgtagaa atgcaaaggt acgagaaatc gtagctggtg
      361 tggcaaagta agaatatagg ttatgaaatg ccatataacg ttacaggcgg tatcaagcca
      421 gcaggcttat agctagtgac ctaaggatat atatgtatag ataagattat cggaacgagg
      481 aaaggtattg ggttctcatc aagagaataa actgacgaag aacaataagc agttgaacta
      541 atgctgaaaa gcagagggcg aacctaagaa attcttgtaa tgagaatgga ggaatgccct
      601 caagtcgtgt atatattaga aaagtattat gttgtttcaa taaggattac gagtaagata
      661 aaaaagctca ctcaatttca agtaaaggag tgaagcctta tgcctaaaaa taaaaatgaa
      721 acattgtgtg tagaagattt aagacacgct gaatattacg aaatgcaaaa cacctttgat
      781 gatttatatg ccaaaagtaa gaatggagat attttcactc atcttatgga tattatccta
      841 tcgagagaaa atatattact ggcatatcga aatatcaaag caaatgcagg cagtaaaaca
      901 gcaggaacag acggtacaat aattaaagat attggcaaat tgccagcaga aacagttgtc
      961 aaaaaagtaa gatacattgt tgcaggcagt ccacatgggt atcgacctaa gccagtgagg
     1021 cgaaaagaaa taccaaaacc aaatggtaaa accagacctc taggtattcc ttgtatgtgg
     1081 gacaggctta tacaacaatg tataaaacaa gtattagaac caatctgcga agctaaattt
     1141 agtgaaaaca gctatggttt tagacctaat aggtcagttg aaaatgcaat aaaagcaacc
     1201 tataaccgcc tacaaatcag ccagctacat tatgtgattg aatttgatat taagggtttc
     1261 tttgacaacg tgaaccattc caagctgata aaacagatat gggctatggg aatacgggac
     1321 aagcacttga tattcatttt aaaaaggata ttaaaagctc caatcaaaat gactaacggt
     1381 acaataacat atccagagaa aggaactccg caagggggaa taatatcccc actactagca
     1441 aacattgttc ttaatgagtt agaccattgg gtagaaagcc aatggcagga aaatcctgtt
     1501 acaaaaaact atgtggttca tatcaataaa agcggtagcc catgtaaaag caacgcttac
     1561 aaagaaatga agaaaacaaa gttaaaggaa atgtatatgg ttcgttatgc agatgatttt
     1621 agagttttct gccgctacaa ggaaagtgct gaaaaagcca aaatagcaat cactcaatgg
     1681 attgaacaac gattaaaatt ggaagtatca caagaaaaaa caagaattgt aaatgttaga
     1741 aaaagatact ccgactttct tggtttcaag attaaaatga taccgagaag aaagaagtta
     1801 gttgttaaat cacatataag tgataaacaa ttcaaaaacc aaaaagacaa gctggtatca
     1861 caggcaaaaa aaattgcttc tccctcaaaa gggaaaacgg aattagaaga aacaagactt
     1921 tataattcaa tggtattagg tatgcaaaat tattatcaga ttgcaacgaa tgtaaatctg
     1981 gattgtatga aactgaatag agctgtaatg gctatcttca ctaacagatt aggtacaaac
     2041 aaaaggggca gattgagaaa aacaggcaga caacttacga caaaggaggc aacaagatat
     2101 ggtaaatcta aaatgcttcg gtatgttgct ggcgagggcg aacctatttt ccctgttgga
     2161 tatatccaac acagaaaacc aatggcaaag gtgtatttag cgaattgcta cactctagag
     2221 ggaagaaaat ttatccacac caatctaagt gttgataaat tactgatgta ccagttaatg
     2281 aaattatctt tggaaaatcg cacaatagaa tacgcagaca atcgaatttc gctattttct
     2341 gctcaacatg gaaaatgtgc tataactctg gaagaatttc aacaagctaa tgaaatacat
     2401 tgtcatcata ttgtaccaac tggagctggt ggaaatgacg attataaaaa tcttattttg
     2461 gtaaaagagg cggtacaccg tctaatacac gctaaaacag aagaaacaat acaaaaatat
     2521 atagctctat tgaagctaaa taaagtccag ctcataagac taaataaata tagagtatta
     2581 gctggcaatc aagaattaaa cttgatatag gtctactaca taaatacttt tcaatataaa
     2641 cacgatggaa cgcggagtgc ggtgaaagtc gcacgctccg tgtgaatggg gggaaaagtt
     2701 tgagatattt ataatatcag gaacttacct atccatatat caatggtttt taaccaatgc
     2761 tcaatcttta gtcttactag cgattgtggt cattggtttg tttttaggat ttaaacgcga
     2821 gttttccaaa ctgattggct tcttggtgat tgctttgatt gcggtaggtc tggtctttaa
     2881 tgcttctggt gtgaaggatg tcttactcaa tttgtttaac cgaattgtcg gtgcctgagg
     2941 gggaatcaca atggaacaga tacgtgttta tattgcgaac cttggaaaat acaatgaagg
     3001 tgagttggtg ggggcatggt ttaccccacc cgtcgatttt gatgaagtga aagaacggat
     3061 tggattaaat gacgaatatg aagagtacgc aattcatgat tatgaactgc cttttgagat
     3121 tgatgagtat acaccaattg aggaaattaa tcggttgtgt ggtttagcgg aagagcttaa
     3181 aggaacgcca attggtgagg tcgcttcaga gattcaacat gccttcttca attctttcga
     3241 ggaaatggta gagcatgtgg atgatatcat ctattatccc gattgtaatg acatgagtga
     3301 tgtagcgtat tacttgattg tagaagctgg tgatttaggc gaagtaccag aacacttgaa
     3361 gacgtatatt gattttgatg cgtgtggtcg agacttggag attggcggga attatttggt
     3421 tacgagtcga ggggtttttg aactaatgta aatcatttgt tagaattgac cagaaatttc
     3481 tatcgtactt ttacttttct atttgatata ctgaaataga aaatatttgt tgataggggt
     3541 gttactaatg gttggcaata agtggtacaa atgtgatctt catattcatt caactgcgag
     3601 tcagtgcttt caggataaaa aggttactgc taaggaatgg gtagaagaat gtttaaacaa
     3661 aggactcgat tgtgttgcat taactgatca caatacaggg gaaaatattg atgaatataa
     3721 gaaagtggct atcgaaaatg gcttagattt ttttcctgga gtggaattaa cgtgtggaga
     3781 aaatggaact catttactag tcctatttga taaaagtgca tgtacaaatg atatctctga
     3841 tttcttaacc aagatgggta taaaaagaga ggattgggcc agcgctgcag cttgctcaat
     3901 gaaatcagtt ttagaagtta ttgattttgc tgagcacgag ggcttgctcg ttattcctgc
     3961 acatatagat gagtttaatg gaatttcttc agcaaaattt ggaaatctag gaaagatatt
     4021 tgaatcagaa aatatatatg cagtacagac ggttcaaaaa gaattttttg aaaatcgctc
     4081 acaaatgatt ccctcatcta agcgtgacac tatctatgat agtgtgaatg ccagatatga
     4141 tggtagagtt ggaaaagata ctttggaatc ttggtataaa tcagttgttg aggcagaaaa
     4201 aaataatatg acatttctta gcttttctga taacccacac tcgaaaggaa attcaaaaca
     4261 tggactttgg ggaataggca caagatattc ctatataaaa atgaaggacg aacctgactt
     4321 gggatcactt cgcgatgctt taatgctagg cgaaactcga gttcattctg atttttctaa
     4381 tttctccatt aatgaaaatg aagttttatt ggaaaaatta agcttttctg ggaccactct
     4441 tagcacaaaa gaagttgtag tcgaattcag cgataattta acttcaatta ttggaggaag
     4501 aggaacaggc aaatcttgta ttacaagatt cttggtctat gtccttggaa aggaagcaga
     4561 acttgatcaa ttttctgaaa tacaaagtga ttatcagaac tttgcacaaa ttgaacataa
     4621 tggctctgga atatttttga aggatacaat tgtgaaactg aatattttct ataaggggac
     4681 aaaatatcaa ataataagaa cacaggatag acattctatt tatgaattta cacaagagaa
     4741 tggtctggtt gaaaaagaaa cagaacggtt gagaatgatt tccgataagg tgagtatata
     4801 ctctcaaaaa caaatttatg aaatttcaaa aaatcaaact agtatactag aattactaga
     4861 tggatataac tctgatttga tttcagagta taaaaatgag attgaaacat gtgtaaacga
     4921 aataagaaaa ttaaattggg atattgtttc tgtgaaaaaa gaaatacaag ataaggcgaa
     4981 ggtagagctt gaaattgaag atttaaaaaa acaagtagaa aagctatctc ataagagtta
     5041 taaagatgtt tatgatgagt attcaaaaga gacagatatt tatagggaac tgaaacgtga
     5101 tgtggaggca cttaaggaaa ttcccaaaaa tctaactgat agtgttgaca aaattgactt
     5161 tggcaatggt ataaaagtta cagacgaaat tgatgaacac cgcggagaat tgattaagaa
     5221 tttagtgacc aatcgggcta agattcaaac aataattaat gaaatgtcag atgaaattga
     5281 tagttataga gcagagctga ataaatcaga ttggaaagtt aactataatg aggtttcaaa
     5341 gaggtatcaa agaggtatca aaaacttagt gaagagttat ctcaagatga attaaaaatg
     5401 ttacaaaacc ttgattcttt atatcaatct ttatcaaaaa ctgaagagcg attggaagaa
     5461 attattcaac aagaaataaa gcttaaagat taccaagttg aggttgactc agcaatgtca
     5521 agaatgaata aatcatatca aaatctctat tctgagagaa gtagttcctc gcgcgaaatt
     5581 ttttctgata ttacaggaat agaggctact attcaaccaa atagggattt caataattat
     5641 gttaaagagc tcagagcttg tattaataag gaggacactt ttgacagtga gtttggatct
     5701 cttattgata agctgacaaa aaattccatt actaatcaag atatatataa tgacatactt
     5761 gatataagag ttagtgggga aagtagtatt ttttcagata aaaaattaat caattctata
     5821 agaaaattga atgatgcaca agttcttgaa ttacaaaccc ttaagccaaa tgatttagta
     5881 gttatccgac ttgaactaaa tggaaaaaaa gttagtttat cgaatgctag tgctggtcaa
     5941 aagacatctg caattctttc tatgattttg gcgtatggaa attcaccact catattggat
     6001 cagcctgaag atgatttgga tagtcaatta attaataact taatcgtaag aagtatcatt
     6061 acaaaaaagg aaaacagaca aattttaatt gtaactcata atgcaaatat cccagttaat
     6121 ggtgattcag aatggttgat tagcatggga gattcaaaag aaatatcggc tgatcagtgc
     6181 gggtcggtag atgaacccaa tatcaagcca agaatatgta ctgtgatgga aggtggcgag
     6241 gatgctttta caaatagagc gaaacgctat ggttttaaac aaattgtaga ataacactag
     6301 agggtgagac atattattat gtccgccctt tttaggagga aaaatgaaaa aaataaaaag
     6361 ctataccagt atctgggcag ttgaaaaagt catttacgca atcaatgatt ttcagttgcc
     6421 ttttcctgtg acttttaacc aaatggcttg gttcgtttta tctttactgt ttgtcatcgt
     6481 atttgcccat gtgcctccac tatctatgat agaggaggtc tttttaaaat acttaggcat
     6541 accggtggct gtcacttggt ttatgtcgca aaagacgttt gatggcaaga aaccactggg
     6601 atttttacga tcctttatca gctatcactt gcgatttaag gtgacttttg caggaaagaa
     6661 agtcaaagaa cagaagaaac gatgggatga acccagtact cttgtaagga gtgtgaacta
     6721 tgtatccgat taagtatatt gaaaataatc tcgtctttaa ccaagaaggc gagtgttttg
     6781 cctactatga attagtgcct tacaattact cctttttgtc acccgaacag aaatttcaag
     6841 tgcatgataa ctttcgccaa ctaattgcgc aaaatcgtga aggcaagatc catgcgttac
     6901 aaattgccac agaaagtagt attcgcgcca cacaagaacg atcaaaaaaa gaaattaccg
     6961 gtagactcaa agaagtagcg aaacaacgaa ttgatataca gacagatgca ttagtatcca
     7021 tgattggcga tagtcagatt gattatcgct tttttattgg ctttaaacta attgcgacag
     7081 atgaagaagt caatctaaag agtctcaaga aatctttctt ttctgggctt caagaatttg
     7141 tctatggagt gaatcatcat ttgatgggcg attttgtttc cttatccaat gaagaaattc
     7201 gctgctattc taagcttgaa aaattaatgg aaagcaaatt ggctcgaaga tttaaagtca
     7261 ggcgagtcac accgagtgac ctgacgtatt tgattgaaca tatttatggc gaaaaaggga
     7321 taccgtttga agaatacgaa tttcagctac caaagaaaaa gctaaaatca gaaacactgg
     7381 tgaaacgtta tgacttatta cgtccaaatc gttgtttaat tgaagaaaaa ccaaggtgct
     7441 tacggatgga acatgagaat catgagtcgt acgtagcgta tttaacaatt aatacaattg
     7501 tgggggagat ggaatttcct tcctcagaac ttttctatta ccagcaacaa caatttacat
     7561 tcccaatcga cacaagtatg aatgtagaga ttgtgacgaa taaaaaggct ttagctaccg
     7621 ttcgtaataa gaaaaaagaa ctgaaagatt tagacaatca tgcttaccaa tctgacaatg
     7681 aaacgaattc caatgtctta gatgctttgg attccgtgga tgaattggaa accaccttgg
     7741 atcagtcaaa agaatctatg tacaaactga gttatgtggt tcgagtgagt gccgaatcag
     7801 tggatgaact aaagcgacgc tgtgatgaag tgctcgattt ttatgatgat accaatgtaa
     7861 aactagtccg gccctttggc gatatgatgg ggctacatga agaattctta ccctcaagta
     7921 aacgatatat gaacgactat attcagtatg ttacgtctga ttttttggcg gggcttggtt
     7981 ttggggctac tcagatgcta ggagaattag aagggattta ctttggctac aatgtggata
     8041 caggtcgtaa tgtttacctg aaaccggcat tggcttcaca aggagtcaag ggttcagtaa
     8101 ccaatgcgct ggccgccgct ttcctgggtt ctcttggtgg aggtaaatcc tttagtaaca
     8161 atctcttagt ctactatgct gttttgttcg gtggtcaagc tgtgattgtc gatccaaaag
     8221 gggagcgagg agggtggaaa gaaaccttgc cagaaattgc ggatgaaatc agtatcctca
     8281 acttgacgag taagtcagaa aatcaaggtc tgcttgatcc ttatgtgatt atgaagaaaa
     8341 agaaagactc ggaaagttta gcaattgata ttctgacttt tttaacagga atttcaagtc
     8401 gagacgggga gaagtttcct gtgttacgta aagccattcg aacggtgact caaagtgatc
     8461 aacgggggtt attacaagtt attaacgaat tgcgaaaaga cgggtcacca atcgcggaaa
     8521 atatcgccga tcatatcgag tcctttaccg attatgattt tgctcatttg cttttctcag
     8581 acggctcgat tacccaatcg attagtttag ataaacagct aaatatcatt caagtggcgg
     8641 atttggtttt accggatgca gaaacgactt ttgaagaata taccaccatg gaattgctta
     8701 gtgtttcgat gctaatcgtc atttccactt ttgccttgga ctttatccat agtaaccgag
     8761 aaatcttcaa aattgtcgat ttggatgagg cttggagttt tcttcaagtg gctcaaggaa
     8821 aaacgttatc gaataagctt gttcgtgctg gtcgggccat gaatgctggg gtctatttcg
     8881 tcactcaaaa tagcgacgat ttattagatg aacgtttaaa aaataatatc gggttgaagt
     8941 ttgcttttcg cagtaccgat attcatgaaa tcaagaaaac cttggaattc tttggtttgg
     9001 atcaggagga tcaaagcaat caaaaacgcc tgcgagattt ggaaaacg
//
LOCUS       DAFLWC010000104         8974 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.107, whole genome shotgun sequence.
ACCESSION   DAFLWC010000104 DAFLWC010000000
VERSION     DAFLWC010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8974
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.107"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            9..82
                     /locus_tag="L1V17_002545"
     tRNA            9..82
                     /locus_tag="L1V17_002545"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:43..45,aa:Ile,seq:cat)
     gene            complement(467..964)
                     /locus_tag="L1V17_002546"
     CDS             complement(467..964)
                     /locus_tag="L1V17_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBN1237257.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(1004..1813)
                     /locus_tag="L1V17_002547"
     CDS             complement(1004..1813)
                     /locus_tag="L1V17_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1237258.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            2147..3004
                     /locus_tag="L1V17_002548"
     CDS             2147..3004
                     /locus_tag="L1V17_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBN1237259.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            2997..3899
                     /locus_tag="L1V17_002549"
     CDS             2997..3899
                     /locus_tag="L1V17_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBN1237260.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            3932..4282
                     /locus_tag="L1V17_002550"
     CDS             3932..4282
                     /locus_tag="L1V17_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBN1237261.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            4331..5254
                     /locus_tag="L1V17_002551"
     CDS             4331..5254
                     /locus_tag="L1V17_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBN1237262.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            5332..6225
                     /locus_tag="L1V17_002552"
     CDS             5332..6225
                     /locus_tag="L1V17_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1237263.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            6263..6826
                     /gene="amaP"
                     /locus_tag="L1V17_002553"
     CDS             6263..6826
                     /gene="amaP"
                     /locus_tag="L1V17_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBN1237264.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            6840..7028
                     /locus_tag="L1V17_002554"
     CDS             6840..7028
                     /locus_tag="L1V17_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBN1237265.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            7041..7943
                     /locus_tag="L1V17_002555"
     CDS             7041..7943
                     /locus_tag="L1V17_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBN1237266.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            7975..8217
                     /locus_tag="L1V17_002556"
     CDS             7975..8217
                     /locus_tag="L1V17_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBN1237267.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(8473..8844)
                     /locus_tag="L1V17_002557"
     CDS             complement(8473..8844)
                     /locus_tag="L1V17_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237268.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         3120 a         1553 c         1741 g         2560 t
ORIGIN      
        1 tttatgatgt acctttagct cagttggtta gagcagacgg ctcataaccg tccggtcgta
       61 ggttcgagtc ctacaaggta cataagaggt tgtgaaaaag ctgccctgca tcaagtaata
      121 agaacagcca agtaaaaaca gcttcttatg tttttacttg gctgttctta ttactgcaga
      181 tgcaagcttt tgaataccgt ttaaggaaga ggttgtgaaa tcagcgtttt gacctgagta
      241 ttagcttaac aaacggaaaa atagttcctc atattttgcc gtttgttaag ctaataccga
      301 gggtcagctg attgaacacc atttaagaaa gaggtcgtga gcctgccgtt tcactctgtg
      361 tcataaaaaa gccaatctac tttgatagaa aaagcacgta ggactaaaac agttctgcgt
      421 gcttttttta ttgtgtgtta aatatcgtaa atgaagatag atatttttat gattcgacga
      481 tagagacgtt gaaatctttc aacagctcta aagcggattc tccgtgtttt ctactggaga
      541 ctaacattgg atcaacaaaa aagtctgctt caggaaaagc actctgcagg cctatcagat
      601 tagagagtac acacaagttt gtttcaatcc cgactacttc gatctctttt tgttcttctt
      661 tgctttcaaa taaagtttcc tggatttcag ctaaagtttc aggtggaatc gtaaagtaat
      721 actttttaat cactcgttca ttttcttgtg gagaaagaag agggatcaat tgcaaatctt
      781 ctcgttcttc ttctttgtcc ttcagttcaa ctggtatatc ccgtgtgaag agaatatatt
      841 cattattttg gcgtgcttta gctaatcttt gagcaatacg ttctgccaat tgatctgact
      901 ctggaatata aaattcgctg tttggatcaa gaatatgatt ttgcatatca ataataacta
      961 acattttctt tcctcctaca ttcatatcgt cattttattc tttttaatag aagtttttta
     1021 aaatataagc aacaccagct tcttcattcg tcagtgttac ttggtttgca atttctttta
     1081 cttgtcgctg tgcattcccc atcgcaatac tcaacccgct gtaattcaac atagcaatgt
     1141 cgttttcttg atcgccaaaa gccatgatgt cactcgattc gattccaagg taatccgcca
     1201 gaaaaacaag tgaatgagct ttagtgatac ctgtaggcgt gatttctaag aaatgcggat
     1261 cagagaatac tgattggata ccatctgctt gcagatctct ttgtagcttc tgtagttttt
     1321 cttcactctt atctgttaat gctaatttaa gatagctaag agaaggatct tccaacatat
     1381 ttaaaatttg atcaaaagaa tggttctgta aattgaaatg ttcataataa gggtcatctt
     1441 tgactagatt tgattcatcg aatgtcagct gatcatcttg ggtttctcgg ctagcaatga
     1501 tggatatttt cgcttcttga gcatagaaga aggcttttct cagtgtatcg ctatctattt
     1561 ttgaacgtct gagaactttc gccatttttc catccttcat ttcagcaatc agtgaaccat
     1621 tggaagaaat caaatagcca ccgattccta attcggaaaa aatatcttta gcagaaatgc
     1681 tgttccttcc ggtagcgacg gttacgattc cgccattttc atcaaatttc cgaagtgctt
     1741 ggatattttc ttctggtatc tttccatttc gatcaagcaa ggtaccgtct aaatcaatcg
     1801 ctgctagttt cattttatct tcctactttc tttttacata tctattttcc tgttacctta
     1861 agattaaatg agaatttaaa aaaatgaaac taacttgctt tgtcattatg aattttttca
     1921 aaaaacattc ttaagaaaaa ggtggctata tatagtagtt tttggtcaat acctttgaat
     1981 aaaaagccat gaaaaacgaa tagttagcgc ttaccgatgc gttttgtgat aaaaaaattt
     2041 taaaatattc aatgaaaaca aagcatatat tttgctttaa aaccaaatga ggaatattct
     2101 agatgtagaa caggttagaa aaagattaga aaaaggagtg attttgatgg agaagagata
     2161 cggcgtagtt cctgtggtaa ctgcttcaga cgaaaattat gctccttact tgagcgtgat
     2221 gatcgcaact gcattagaaa attgcaataa aacaagacgc ataaaatttt atgtgattga
     2281 cgatggtcta tcagaatata gtaaagaagg attggaagaa acggtaaata aatattcaag
     2341 taatgcaagt atccaattcc tgacagtgga aaaagatatc tacgaagact tcctagtcag
     2401 tgaccatatc acaactaccg cttacttaag aatttcttta ccaaacttat tagctaaaga
     2461 ggattataag aaagtccttt acttagattc agatgtgtta gtactagacg atatcgtaaa
     2521 actatatgat gagccgttaa atggaaaaac aatcggcgct attatcgatc caggccaagt
     2581 gaaagctttg gaaagattag gaatcgattc cgatgacttg tacttcaatt caggagtgat
     2641 ggtgattgac attgatcaat ggaataaaaa agaaattaca gaaaaaacta tccattacct
     2701 cagtgaaaat ggcgatcgaa tcatctatca cgaccaagat gctttgaatg ctgtacttta
     2761 tgaagattgg gaacaacttc atccaaaatg gaacatgcag acttcgctga tttttgaacg
     2821 tcatccagca ccaaatgaaa aatatgaacg tcagtataaa gaaggaaatg aaaaaccttc
     2881 gatcgttcac tttacaggac atgataaacc ttggaatacg ttgaaagatc atccgtatac
     2941 caatttatac ttaaaaaaat tagcacacag tactctaacg aaagtaggcg agatcaatga
     3001 ataaaaaaga aatagcagta gtcgcaagtt gtaacacaaa attcgtacca catttagctg
     3061 cattatttgt ctcagtatta gataattgca acccgtctaa atttgttcgg ttctatgtga
     3121 ttgacgatga tatcgatttt gaaagtaaac agcttttacg cttctcagtg aaaaacgcac
     3181 gaatgaactc agatgtggaa ttcttgaaaa tcaataaaga attctttaca aatgtggtaa
     3241 tcagcgatcg tattccagaa acagcttatt atcgtattgc gattccggaa ttgttccgcg
     3301 gcacagaagt tgaacgtatc ttatatatgg attgcgacat gatcgcttta caagatatct
     3361 ctaaattatg gcgtcttgac ttcggtgatt caatcgtagc agctgttgaa gacgctgggt
     3421 tccatcaacg actggaaaaa atgaaaattt cagctaaatc aatgcgttat ttcaactcag
     3481 gtttgatgct gatcaatgtg aaaaaatggt tagatgaaaa tattacgcaa aaagtattag
     3541 atttcatcga acataatcca gaaaaattac gattccatga ccaagatgca ttaaatgcta
     3601 tcttacatga ccgttggtta ccacttcatc cgcgttggaa tgcacaaggc tatatcatgg
     3661 caaaagcaaa aaaacatcca acagcagcag gtgaacgtga atacgaagaa actcgcaaca
     3721 atccttacat tatccatttt tcaggacatg tgaaaccgtg gagcaaggat tttgaagggc
     3781 caacgaagaa atattacgaa aaatatgcag ggatgacggc tttccgttgt gtagctaaat
     3841 tccctaaata tccaaaatat gcaaaagttc aaccaaaaac agatgtagtt gttaaataat
     3901 agaagaccac aactgaagag ggggagtagg aatggaaatt acaatgtcta aaaatgcagt
     3961 agagacgtta attgaaaagg ttggggaaaa tacaaaaatc gcactcgcgc ttatcaatga
     4021 ttccgatcca tttctaaggg acaaaggtgc ttttgcaaaa ggcagctttt ttcaaatcat
     4081 tccttttgtt tcggaatttg gagaatatgc gactaaaatc gagcatccat tattggacat
     4141 ctatacatct aaattagagc aaaattattt cggtaaacga ttgaacatgg acttcaacaa
     4201 acagcttgac agcttttcat tagaaaatga aatcgcagta ctcgattata atatcaaatt
     4261 aaagaactgc ttcttcagct aatagtttcg agaaagtcca aaaaggaggt atacattgag
     4321 atactacttt gtggatgaag aaaagaatgt aatagaaaca gatgaaaaaa aatataattg
     4381 gctcgtactt gatagtgcaa agcccgaaga gattgagcaa gcaatcgaag aattcgagct
     4441 tcctgatgat attttcgtag gaaccgaata tccggaagaa gtttctcgga tggagcgcct
     4501 ttatgagacg aaactagagc atccattttc tttggtagtg attaatctag atcagtcaga
     4561 taatcgtatc gaaaaaaaat taacgccaat atcttttgta ctttccgata atctcttgat
     4621 tacttgtatc gatagaaaaa ccgaatttgt ggatcggctg ctgacaaagc atggaaatca
     4681 tttaaactcg tttgaaaaga tcatcacgta tacattatta gatatttaca cccattacgt
     4741 gaaagaacta agagagatga aaaagcgaat tgacgctttg gataaagcag ctcgtaaaac
     4801 aacggaaaat gaagaactgt ataaacaggc agatcttgaa agagacatcg tatatatcga
     4861 tcatacctta agagatcaac gggaaacaat ggatcaatta tggaattctg aaactttcat
     4921 caaacgttta gacgatgaac agctactcta tgatgtccat ttgagacagc gacaaacaga
     4981 aaaaatgatc gagatctatc gagatttatt agagagtatt ggtgatctat tcaacgggat
     5041 gatggacaat aatctaaatc atatcatgaa atatctagat tcagctgcat taatcatttc
     5101 cgttccggcg ttgttcgcag ggatttgggg aatgaataca ggaggattac cgggtaaaag
     5161 ttctgctcta ggctttatac tcgtagtctt tggctctttg atagcagcag tagttttagg
     5221 ttaccattta taccggaaag attatacaaa ttaaagaatc tatttaaaac aggtatcaaa
     5281 caaagaaatt tgttttggca atacaattta aaaactagga ggaatacagc aatgacagaa
     5341 ccaaaattaa tcgacccgcg aaacttgtac catacggaga aatttcctaa acaagatcag
     5401 gatacaccag ctttacagca gaatatgatt cctgttcctg attgtggaga agaatcctat
     5461 gaaggcaata atcaactaga aaaccgccgt gtactaatca ctggtggaga ttcagggatc
     5521 ggtcgtgcag cagcgattgc atttgctaga gaaggggcag atatcgctct tcaattcttc
     5581 ccaggagaag aaaaagatgc agaggaagta gcaaaatacg tgaaagatgc aggacgtaag
     5641 attgtcttac taccttttga tcttcgtgac gaacaagcac ctaaagaaat catagataaa
     5701 gccgtgagtg aacttggcgg gctagatacg atggtactaa acgcaggaca gcaaatttct
     5761 tgtcagtcta ttgctgagtt accacttgag caagtcaaag acacatttat gataaacatc
     5821 atcgctatgt ttgctttagt gaaagaagct gttccgcata tcccagcagg aggagcaatc
     5881 gtaacaacaa cttctgttca agcattcaat ccaagcgaac atttattaga ttacgcagca
     5941 acaaaagctt caatcgctaa ctttacgatc ggtttagcaa aacagcttgc acctaaagga
     6001 atccgtgtaa atggtgtagc acctggtcca atttggacac cattacaact agacgaagga
     6061 caaccttctg attcgatccc tgaatttggt cagcaaagtt tactagaacg tgcaggtcag
     6121 ccaggagaat tagcaccagt ttatgttttc ttagcatcga ataaagcaag ttatgttaca
     6181 gcccaaattt acggagtaac tggtggagaa gcgatcaact tataagaagt tgatcgtttc
     6241 acccctatga ggaggtgcga aaatgaataa aggtgtaaaa acgatcggag tgatcggaac
     6301 attacttttg ctatctgtgc ttttgtttgc gatactatta agtgcaacct atccattgcc
     6361 ttttcagcta gagaagtttc gattcttttc catcactaat tcatacgtgc aacaatatgt
     6421 attttggctt gccgttgcat ttgctatttt gacaattatc acgttacttg ttttcctgtt
     6481 ttatccaaaa acaatcggaa actttctact gaaacatggt gatggggagt tgacgttgga
     6541 taaaaaagca attgaaggaa tggttcgttc tcacttgcat gaagatgaat tcatccattc
     6601 accaaaagta aatgtcaaag caacgaaaaa caagatcgcc gtcaatgtaa aaggggagtt
     6661 gaaacgaact tcagcactca ttggtaaaac aggaacattg atgaaagaaa tcgaaaatga
     6721 agtacaacac atattgggaa caaaagagcc agtgaaagta tcggtgaaat acacaggctt
     6781 tgaagaacca gctaaacgaa gcaatgaccg caaacgagta gaataggggg ggaccaaaaa
     6841 tgaaagaact attttcgaca tacaagctcc ctatcatctt tggggtactt ggattgatat
     6901 tagccgtttt atggatcacc gtgggctttt tcaagacctt attgatcttg atcatggcag
     6961 cgatcggcgt cgctatcggt ttttatctga aacaaacgaa aatcttagat cactatttta
     7021 aatcttagga ggaaacatcc atgaataaca ataacaaaaa taataacaat aaaatgaaca
     7081 accaaaaacc agtgtctgca catccagacc caacgacacc aaaccaatca aatggtgtga
     7141 acgatgaaaa gaacaaaaca gcaccagtat ctgcacatcc agatccagta gtccctaacg
     7201 ttcaacaagg agtagaagag aagaaacatg atgcagaaaa gcatgcacct catcatccag
     7261 gaactccaga atctaaagtt ccagaacaac atgatgcaat cgatccttct aaacctgtgg
     7321 aagagcaaaa acatccttct gaccatgcga aagcacaaga aaaacttagt tctgaccaca
     7381 caaacggaca aggaaaactt ggttctgatc atacaaataa ccaaggaaag catgattctg
     7441 aacaggaaga ttcaatgcgc ggtgagctga attatgaaga taaagttgtg caaaaaatca
     7501 tcggaatcgc aattgaacaa gtagacggtt tattatctgc aaacggtggt ttcttctcta
     7561 atgtggcagg aaaacttgtg aatacagata atgtaacggc tgggatcgaa acagaagtcg
     7621 gtaaaaaaca agtagcagtt gatatggatg tcattgtgga atatggcaaa gatatcgaaa
     7681 aaatctttga agaaatgcaa gaagtaatcg gcaaagaagt aaaaaatatg acacatttag
     7741 aagtgatcga agtcaacgct aacgtagtgg acatcaaaac aaaagaagaa tttgaaaaag
     7801 atcaagaaac ggtgcaagac aaagtaactg acgcagcgaa aaaaaccggt gaatttgctt
     7861 cgaatcaaac agataaagta aaatcagcag ctggaagcgg cgcacaaaaa gtaaaagaaa
     7921 atacagaacc acgggttcag taataaggaa gtaaaacatt aggaggaacg aaacatggga
     7981 tttatttggt cacttatcgt cggaggaatt atcggagcaa ttgcaggagc aatcacgaat
     8041 aaaggttctt cgatggggat tattgcaaat gtcgtagcag gtttagttgg atcagcactt
     8101 ggtcaagcat tattaggttc ttggggacca agtattgcag gaatggcaat cgtgccatca
     8161 ttgattggtg ccatcatttt agtactaatc gtatcattct ttgctcgaaa actgtaaaaa
     8221 gacttttaaa aagaggtcgt gaaaaagctg ttcttcatca agtaataaga acagccaaac
     8281 aaaaatagct tctcatattt ttcatttggt tgggcatatt atcgaagatg caagcttttg
     8341 aacactgttt atacggaata agaggctgtg acaagacttt tgtcacagcc tcttatttat
     8401 gcgggcaaat tcccaattag atttttaaaa gtttttcctt aaatgtgtct ttattgatac
     8461 agagaagctt ctttaataaa acaatgcctc cctaaatttt cttgagatag gaaaggtgaa
     8521 catacaaaat aatacgacca ctttgaaaac ccagatgatc cacaaatgga tcgtatgata
     8581 ctgatgaagt aaaaagcaat ggatcagaaa ctcaaagaga ttgaaaaaga caaggaagaa
     8641 ataatatctc ttttttactc ttgtctgttt tagccaataa tagctcgtaa agtaatctag
     8701 acaaacaaat agaagtaaac aaagtttcgt aagagcagca atcgtatcat gttgctctgc
     8761 tagacgattg acgagcagga aaaatgttgg taatggaata tagatcacga gtaatgaaag
     8821 aaaaaagtaa acaataaatg gcatactatt cctcctaatt gtgtgagttc gccctcattt
     8881 taaaataacg atatttgttt gtgaagcttt ttcgtgtcgt aacaaatgtt atctaatgta
     8941 tttttaaata aataatcatt attatcaaaa taat
//
LOCUS       DAFLWC010000105         8552 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.108, whole genome shotgun sequence.
ACCESSION   DAFLWC010000105 DAFLWC010000000
VERSION     DAFLWC010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8552
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.108"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            476..1339
                     /locus_tag="L1V17_002558"
     CDS             476..1339
                     /locus_tag="L1V17_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBN1237269.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1468..3090)
                     /locus_tag="L1V17_002559"
     CDS             complement(1468..3090)
                     /locus_tag="L1V17_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1237270.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3339..3860
                     /locus_tag="L1V17_002560"
     CDS             3339..3860
                     /locus_tag="L1V17_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBN1237271.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="L1V17_002561"
     CDS             complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="L1V17_002561"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HBN1237272.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5941..6759
                     /locus_tag="L1V17_002562"
     CDS             5941..6759
                     /locus_tag="L1V17_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBN1237273.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6862..7059)
                     /locus_tag="L1V17_002563"
     CDS             complement(6862..7059)
                     /locus_tag="L1V17_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237274.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7228..7806
                     /locus_tag="L1V17_002564"
     CDS             7228..7806
                     /locus_tag="L1V17_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBN1237275.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            7901..8038
                     /locus_tag="L1V17_002565"
     CDS             7901..8038
                     /locus_tag="L1V17_002565"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237276.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
BASE COUNT         2603 a         1525 c         1672 g         2752 t
ORIGIN      
        1 ccactaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
       61 gagaagctgt tttttgaaat tgttccttgt gactcggagc taaacggcag gctcacaacc
      121 tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
      181 tgaggaacta ttttttccgt ttttttctct aatactcagg tcaaaacgct gatttcacaa
      241 cctctgattc acggtgttcc agaagtagct tctacggaaa taagccgaaa tttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttat tttgattaga acttgcgaaa ataaaccggt taaagtgtgt ctagcgcaag
      421 agatttgcta taatagacga taagggtaaa atgtaacgag aaggggttga aaaatgtgta
      481 tcaaattgta acagattctt gttgtgatct gccataccat gtattagcaa aagaaaaagt
      541 tgatttttta tcaatgaatc tccaattgaa tgatcaagag ttagtagatg acctcggaaa
      601 gacattcaat tatgaccgct acatgaatca gctgaaaaat ggtgcgatgc ctacgacatc
      661 acaaatcaat gttggccgat atttagaatt tttccgttct tatgcggaaa aacagattcc
      721 tgttttatat gtggcttttt ccagtggatt aagcggctct tacagtagtg cgcttcaagc
      781 ggttgaattg ctgaaggaag aatatgaaga ccctgagatc tatgtttttg atacaaaagc
      841 tgcaagtatt ggggaagggc ttttagtatt ggaagctgta agattgaaaa aagaaggtaa
      901 aagcatcgaa gaaaccctag agtggctgga aagtaattat ttgaaagtcc attcatgggt
      961 aacagtagac gatctgaaat atctagaacg aggcggtagg atttccaaag caagtgctac
     1021 tcttggcagt ctattgagtg taaagcctat tattacggtg gataaagaag gaaggctgac
     1081 gaatgttgac aaagttcgag gaagaaacaa gtcgatccag acaatcgtca atgagacggt
     1141 aaaaacaatc gttgcaccac ttgatcaaat cgtttatgtg gcttacgctg gggatctaga
     1201 gagcgcggag aaggcaaaac ggcttttgga agagcagata aagatgaaag atgtgaagct
     1261 ttatccctta ggaccaacga tcgccagtca cacaggctat ggctgtatcg cgattttttc
     1321 gatgggaatc agtcgataaa agcagtaact cattctgtaa aaaagcccag aaattgattg
     1381 taacaaaaac agcgactctt aaaagataga tgagcatcct atctcttaga ggtcgctgtt
     1441 tttttatttt ttaagctaaa taggccatta tgcccataac tcgttcaatt gtttttgaat
     1501 atctgcattt tccaaaaatt catcatatgt cgtatcagct cgatcgatca cacctttatc
     1561 cgaaacggca atgatgcggt ttgccaatgt ttggataaat tgatggtcat gtgacgcaaa
     1621 taagattgag ccagtaaatg ccatcaagcc gtcattcaat gctgtgattg attctaagtc
     1681 taaatggttc gttggatcat ctaatacaag tacgttagct ttcgaaagca tcatttttga
     1741 aagcatgcaa cggactttct ctccaccaga taaaacattc actggtttca atacttcttc
     1801 accagaaaac aacattcttc ctaagaagct tcttaagaag gtgttatcat cttcttcttt
     1861 acttgcatat tgacgcaacc agtctaaaat cgttagatca gtatcgaatt ctttcgttgt
     1921 atcctttggt aaataagaat tacttgttgt cacaccccaa cgtactgttc cagtatctgg
     1981 cgtaatttca cccatgataa ctttgaatag cgttgttgtt gttatatcat tttctgcgac
     2041 gaaagcgacc ttgtcttctt tgctcaaatt aaaagatata tcatctaaaa ttttctttcc
     2101 atcaatcgtt acacttacat tttctacctg caataagtcg tttccaatct cacgttcagg
     2161 tttgaatcca acgaatggat aacgtctaga agaaggttgg atatcgtcta aagtaatttt
     2221 ttcaagcatt tttttacgtg aagttgcttg ttttgatttt gatgcattcg cactaaagcg
     2281 ggcaataaat tcttggagtt ctttgatttg ttcttctttt ttggcatttg cgtttgcttg
     2341 aagtttagcc gctagttgac tagattccaa ccaaaaatca taatttccta cataaagttt
     2401 gattttacca aaatctagat ccgccatatg tgtacatact ttgttcaaaa agtgacggtc
     2461 atgggataca acgatcacag tattttcaaa attgatcaaa aattcttcca gccaattgat
     2521 cgattggata tccagaccgt ttgttggttc gtctagcaaa agaacatcag gtttaccaaa
     2581 tagtgtttgt gctaataaca cttttacctt ttgtccacca gttaattcac tcatttgctg
     2641 atggtgcaat tcttcaggga tgttcagacc ttgcagtaaa acagctgctt ctggttcagc
     2701 ttcccatcca ttaagctcag caaattctcc ttctaattca gctgctcgaa taccatcttc
     2761 gtcagtgaaa tcctctttca tgtaaatcgc atctttttct ttcagcactt catacagacg
     2821 cttgtgtccc atgatgactg tttcaagtac agtatagtct tcatagtcgt aatggttctg
     2881 tttcaatacg gccatccgtt catctggtcc catagtaacg gaacctgtgg aaggctgcag
     2941 atcccctgat aacactttaa ggaacgttga tttacctgca ccatttgcac caatcaagcc
     3001 atagcagttt ccgggggtaa atttaatatt cacatcatca aatagtttgc ggtctgaaaa
     3061 gtgcaaactc acatcattta cagtaatcaa tttttttcct cacttttatc attattagtt
     3121 ttgacaagtc ttatagaatt atatagggga aaggtaaaag attcaaggca atcgaacatt
     3181 ctttgtgttt cacgtgaaac agaatgaaaa aaataaaaat aaaagcggag cgaaaatagc
     3241 tactatagga tttattagtt tgcaacagca taatttttga cgttatttat aagagggagt
     3301 actataaaac tgtaaaagaa atgaaagaag gattgaaaat ggatgaaaaa agaaccatcg
     3361 actggggctc attgattttg ggaattttat ttgtacttgt ctcattgtta tcatttcaag
     3421 accctgtcgg aaatttagtt gcaattgtag tagtctttgc gatttttgcc tttattaaag
     3481 ggatatttga actgtttgta cggaacagat taaaagagct aacaggatat aaaggaaaga
     3541 tgcccttaat aatcgggatc atcgatattc tagttggcgt ctttttctta ttcaatattg
     3601 gtgcaggagt cgcagcattg ccttttgttt ttgcagtatg gtttattgct gattcagttt
     3661 tagcgttatt tactgctgac ttggcaagag gagtaagtga aggatattat tggtttacga
     3721 tcatcgtcaa tattttagga attttattag gaattttctt attgtttaat ccaatttctt
     3781 ctgcgttgac attaagcttt ttagttggat tctattttat gttatttggt atcacacata
     3841 tcgtctatgc atttagataa gtaaaatcaa acaaataaaa aagccggctt ccgattacag
     3901 ttttactgtt gtaattggaa gccggctttt ttatcatgga caaatatgca cgaggtgatt
     3961 tttaggtgtc gagacaaatt tatgcaaaaa tgtgagaagc tatatacaca aattttatct
     4021 taatactcga agcatagcgc agttgtcaca acctcttttc atataattca ttcaatactg
     4081 gcaaatcatg gacttcatat ttttctttga atgcttggat ttcttcttca gaatattttc
     4141 ttggatctaa atgcagatct tctactggca atgggcgctt gttattgatc ttcacatcga
     4201 ttactacagg acgatctgat tttgcagctg catcaaaggc aaatcgaagt tgcgagtatt
     4261 ctgtgactgt aaagctattt gccccgagcg cttctccaac tttaccgaaa tctgcatctt
     4321 ctaaaaatac accaaatttc ttttgttccg tatcttcttg ttctgcttcg atgaaaccaa
     4381 aagaatcatt cgaaaagaca acattaataa ttggaagctg atatttgact tgtgtaatga
     4441 tatcttgcat gaccatagca aacccgccat caccacttaa ggtaaatact tgtttttctg
     4501 ggtagcttag ttgtgcggca attcctcctg gcacaccatt acccatagtt gcgaaccatc
     4561 cagatgtcgt atgtttttgt ttaccgttca tattcaataa acgaatagaa tggatagtcg
     4621 tgttaccgac atctgtgacg aaaatcgcat cgtcttcagc aatacgattg atttctttat
     4681 agacagcctc tggacgaatc ggttcttcct ctcgatcttc aaaagatttc aaccaattta
     4741 cccatttttc tttattttct tgatttgcta ggtaccagct atcagcaggg cgagcatccc
     4801 ctaactcgac aagtctttgc aaagctgtgt ttgcatcacc gaggatcgac aaagatgttt
     4861 catggcgtcg tccaaatttt gacgcatcga tatcgatttg gataaattca gcagttggat
     4921 taaaaaatgc acgtccaaat gggaagtcgc taccgacaaa taagatcaga tcggcttctg
     4981 ccaatgcttc atttccgggt ttagtagcga cacgtccagc aaaaccaaga aagttttcat
     5041 aatcatcagg aataattcct tttgctagaa cggaagcgac aacaggaact gaaaaatgtt
     5101 ctgagaattc tttgatttgc ggaaatccgt ttcgcgttcc ttgaccaaca taaagaactg
     5161 gtttttttgc tttttcaaga taaggcaaag cagctagcaa atctttttct tctggtaata
     5221 tcacacttgt tttgtgagtg tgagcggtgg agaaaggttg ttcgtcaatt tcttcaaaac
     5281 caagatcaac agggatagtc acgatagcca cgcctttatg ctcataggcg gctttaatgg
     5341 cttcatctac tacatgcgga agactttgtg gtgtcatgac tgtacgattg tatacgctaa
     5401 catctgcgaa aataggattt tcatttagtt cctggaaaga gttatagttc atggatgtag
     5461 aagcaacttg tcctaagaac gctactagag gcacatggtc catctgtgca tcatacaaac
     5521 cattgatcaa atgtgtcgca ccaggtcctg cagagccgaa gacagcgccg actttccccg
     5581 ttaattttgc atctgcagcg gctgcgagtg cgccgacttc ttcatgacga acttgaatgt
     5641 agttgatttc ggttttttct tgatatagcg catccataat tgaattgaaa gatcctccgg
     5701 gaatgccgta aatatggtcg ataccccagc tttcaagaac ttttaccatt gcgattcctg
     5761 cattgatttt tgacatggtg tttcactcct ttagcaatga tgatacataa attttttgta
     5821 tctagagtat agaacttttt atcgaaaatc ccaactaatt cgtcttttca caaaaatgta
     5881 gtcatgtttt tgggaatatg ctagagtagt acatagatag attcaagaga ggggaatggc
     5941 atggttgaat ggctattgag acttgaacct tggcagcaag cacttgctgg gacagctttt
     6001 acttatttta tgacagctct tggtgccggg ttggtttttt tctttaaaga aatcaaaaaa
     6061 gaagtgctaa acttgatgtt aggatttgct tctggtgtca tgattgctgc aagtttttgg
     6121 tctttgttag atccggctat tacaaaagca gaagaaaatg gagatattgc ttggctagtt
     6181 gtaagtattg ggtttggttt aggcggtgtg tttttatata tggcagataa aacactgccc
     6241 catatgcatt ttggaccaca acatgaagca gaaggattgc ctacccattt aaaacggacg
     6301 atcttgcttg ttttttctat tacattgcat aacattcctg aaggtttagc cgtgggggta
     6361 gcattcggtg cagcagcaac tgcggataat ccgacagccg ctatattagc cgctgtttcg
     6421 gtggcgctag gtattggtat ccaaaacttc ccagaaggag cagctgtatc aatcccgttg
     6481 cgacaagaag gtctgagtcg taaaaaggcc tttgtttacg gacaagcttc tggaatcgtt
     6541 gaaccaattg ctggagtgat tggagcgcta ctagtaacga aagtggagct gctgcttcct
     6601 tatgcacttg cttttgccgc aggagcaatg atttatgtcg tggtggaaga attgatccct
     6661 gaagcacagc agacattgtc cagcaaacgt cattttgcag tttttggcgt catgagtgga
     6721 tttatcatta tgatgatttt ggatgtggca ttaggataaa taaaaaaaat atatatgata
     6781 tatcaaatag ggccgcgaac ttatatcgcg accctatttt tttagtaagt tatatcataa
     6841 tgaagtgaat ggtatcatac attaataata gttttttcta tgtgtatttc ctttgatcca
     6901 gcgaacaagc cagatgataa gtgcgattgg gattagaact ttgaccgcaa accataaaag
     6961 cccgcttagg acactgacaa aaagactgat gacgaagcta gctgcaatta gcactaaaag
     7021 aaccatgaag atatttaaga acatattttt ttgacgcata caaaaccctc ctcttgttca
     7081 ttctttacta tagaaaaagt ataacaggga ttgtttaaaa acacctccaa ctgaagactg
     7141 atttttactt catctactta aatgatcaaa caattgcttt ttctctggtt tatcatctaa
     7201 aatagagcgg aaaaggagga gaatatcatg cctaaaaatc gtcttgaagc atttacagat
     7261 gctgtaatcg cgattatcat gactatttta gttttagaac ttcatgaacc taacggagac
     7321 acgtgggagg cgctcgctgc attaggttac cgatttttta tctatattgt cagttttatc
     7381 attttagcga tttattggaa caatcatcat catttatttc aagttgtaca taagataaat
     7441 ggacgggtct tatgggcgaa cagtttcttt gtttttgcgc tttcgctttt tccgtttgca
     7501 acttcatgga tcagtgagta catcaatagc ctggctccag aaatgactta tggttttgtt
     7561 accttgaccg ctaatattgc gtattatatc ttggcaaaag aacttgtcaa agcaaataaa
     7621 ggccacgaga aagcattgaa ggcgatgttg aataattaca agaaatcgta tctatcgatt
     7681 ggtttgaatg tgttaggaat tgtcttaggg tatttagtag cgccagtagc cgtgctgatc
     7741 gcaaacatcg tgattctagc tgcttggatc atcccaagtc gtaccatcga atcacaatat
     7801 cggtaaaatg atccgtgttt aaaatttaag agaaaaatat agaaaaaata aataaacgat
     7861 caaatatccg agtgatacta gtattcaaag agggatgcag atggatcaaa aaagaattca
     7921 tgtaggactg attactagtt ttgtcacgat gcttatttat ttggatcaag gtcatttgac
     7981 ttggacagta gttggtgtcg taggattttt gacattattc acagcaataa aaaaataaac
     8041 atctttatgt aatctgatgt tctatctatt taagaaaagc atgtttacag cagtatgatt
     8101 ctgttgtaaa cgtgttttta tttgtggaaa atttaatttt tagaaaagtg tatcgaaaaa
     8161 tagatagtta gtttttccac agtggataac ttcgtaagag ataaaaataa aaaattagtc
     8221 aaagaagggc gtatagattt cttttgatag gagatataca acagaaatga ataaatatta
     8281 acgtgttttc aaacagtata aaacggtgtg gtttttggaa taaaaaaata acatatctca
     8341 ttttacactt ttgttatttt atacttaaaa aataacgaca cagaaaatac cgtgtctcag
     8401 atttctctac tacttctaaa aactactgtt tttttccttt gaaatgcctt caaaaagtag
     8461 gatcaggcag aatatactgg cagaatcaag gagaagggag cctaaataag gagaaaaacc
     8521 atagaaaata taaagtaatt acttataaaa ca
//
LOCUS       DAFLWC010000106         8494 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.109, whole genome shotgun sequence.
ACCESSION   DAFLWC010000106 DAFLWC010000000
VERSION     DAFLWC010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.109"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..173)
                     /locus_tag="L1V17_002566"
     CDS             complement(<1..173)
                     /locus_tag="L1V17_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006735101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBN1237277.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFL"
     gene            complement(593..1714)
                     /locus_tag="L1V17_002567"
     CDS             complement(593..1714)
                     /locus_tag="L1V17_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HBN1237278.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVVDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYRPG"
     gene            2042..3451
                     /gene="istA"
                     /locus_tag="L1V17_002568"
     CDS             2042..3451
                     /gene="istA"
                     /locus_tag="L1V17_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HBN1237279.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /gene="istB"
                     /locus_tag="L1V17_002569"
     CDS             3448..4176
                     /gene="istB"
                     /locus_tag="L1V17_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HBN1237280.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4304..5215)
                     /locus_tag="L1V17_002570"
     CDS             complement(4304..5215)
                     /locus_tag="L1V17_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBN1237281.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="L1V17_002571"
     CDS             complement(5232..6239)
                     /locus_tag="L1V17_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBN1237282.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="L1V17_002572"
     CDS             complement(6236..8365)
                     /locus_tag="L1V17_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBN1237283.1"
                     /translation="MKKKLFRIVGIVFISIVTLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..>8494)
                     /locus_tag="L1V17_002573"
     CDS             complement(8370..>8494)
                     /locus_tag="L1V17_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBN1237284.1"
                     /translation="NGQCLMQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2599 a         1728 c         1486 g         2681 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtctgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccacca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggacttga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca gagtgacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg tttt
//
LOCUS       DAFLWC010000107         8122 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.110, whole genome shotgun sequence.
ACCESSION   DAFLWC010000107 DAFLWC010000000
VERSION     DAFLWC010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8122
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.110"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            71..463
                     /locus_tag="L1V17_002574"
     CDS             71..463
                     /locus_tag="L1V17_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237285.1"
                     /translation="MLDDRLTCSNCGTLFYYEEVRNIVKHRKKEMPIRCPNCNEVIKR
                     KLSHGYFVSYELYEESKINLKKKPKYYKNLKTGAIITEKEFKNLVTEEESRFYNLSGN
                     ICPGFMDQIIENESIESIENYVPVDLPK"
     gene            complement(636..818)
                     /locus_tag="L1V17_002575"
                     /pseudo
     CDS             complement(636..818)
                     /locus_tag="L1V17_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            805..1002
                     /locus_tag="L1V17_002576"
     CDS             805..1002
                     /locus_tag="L1V17_002576"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237286.1"
                     /translation="MKDSIVEPEGMENTFELYNKTTVDKLIPILVPTDLNGHDVLLRF
                     NGFLGEDYRYLKISDPQPLTE"
     gene            complement(1045..1620)
                     /locus_tag="L1V17_002577"
     CDS             complement(1045..1620)
                     /locus_tag="L1V17_002577"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBN1237287.1"
                     /translation="MAQLFYRYGTMNSGKSIELLKVAHNYEEQGKRVIIMTSAIDTRS
                     GFGKVESRIGVSKPAIAITSEMDVYGELVEIIDQYGKVDCILVDESQFLSRENIIDLS
                     LIVMNEEVPVICYGLKNDFQNNLFKGSEALLTFADKIEEIKTICHFCNKKAVMNARIV
                     DGIPVYSGEQIVVGGNEDYLSVCRNHYYNED"
     gene            complement(1775..2301)
                     /locus_tag="L1V17_002578"
                     /pseudo
     CDS             complement(1775..2301)
                     /locus_tag="L1V17_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2758..4269
                     /gene="gadC"
                     /locus_tag="L1V17_002579"
     CDS             2758..4269
                     /gene="gadC"
                     /locus_tag="L1V17_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015082498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate:gamma-aminobutyrate antiporter"
                     /protein_id="HBN1237288.1"
                     /translation="MNKKKLSLFGFFALTASMVLTVYEYPTFATSQLHLVFFLLLGGI
                     LWFLPVALCAAEMATVEGWKDGGIFSWVSQTLGERFGFAAIFFQWFQITVGFITMIYF
                     ILGALSYVINFPELNTDPFIKFIGVLVIFWVLTFSQLGGTNRTAKIAKAGFVIGIVIP
                     SIILFGLAAAYFIGGNPIQMAINAKAFIPDFSQLSTLVVFVSFILAYMGVEASASHIN
                     ELENPQRNYPLAMFLLVILAIALDAIGGFSVAAVIPQHDLSLSAGVIQTFETLILHFN
                     SHLHWLVKVIALMIACGVMGEVSSWVVGPSRGMFAAAQRGLLPVFFRKTNKQDVPVPL
                     IMIQGIIVTIWAAVLTFGGGGNNLSFLVAISLTVVIYLVGYLLFFLGYFVLVFKKKDL
                     KRTYNVPGKTVGKTIIGGIGFILSVFALLISFVPPASIAASEHRTYQIILLISFVVTV
                     LLPFIIYEVHDKSAHTTIEEPTHVKAEDVNPAVYPAARGEHHVTKNDEHILKH"
     gene            4282..5682
                     /locus_tag="L1V17_002580"
     CDS             4282..5682
                     /locus_tag="L1V17_002580"
                     /EC_number="4.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HBN1237289.1"
                     /translation="MLYGKDNQEEKNYLEPIFGSASEDVDLPKYKLNKESIEPRIAYQ
                     LVQDEMLDEGNARLNLATFCQTYMEPEAVKLMTQTLEKNAIDKSEYPRTTEIENRCVN
                     MIADLWHAPNNEKFMGTSTIGSSEACMLGGMAMKFAWRKRAEKLGLDIQAKKPNLVIS
                     SGYQVCWEKFCVYWDVELREVPMDEKHMSINLDTVMDYVDEYTIGIVGIMGITYTGRY
                     DDIKGLNDLVEAHNKQTDYKVYIHVDAASGGFYAPFTEPDLVWDFQLKNVISINSSGH
                     KYGLVYPGVGWVLWRDQQYLPEELVFKVSYLGGEMPTMAINFSHSAAQLIGQYYNFVR
                     YGFDGYRDIHQRTHDVAVYLAKEIEKTGIFEIINDGSELPVVCYKLKEDPNREWTLYD
                     LSDRLLMKGWQVPAYPLPKDLDQLIIQRLVVRADFGMNMAGDYVQDMNQAIEELNKAH
                     IVYHKKQDVKTYGFTH"
     gene            complement(5847..7282)
                     /locus_tag="L1V17_002581"
                     /pseudo
     CDS             complement(5847..7282)
                     /locus_tag="L1V17_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328084.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            7675..>8122
                     /locus_tag="L1V17_002582"
     CDS             7675..>8122
                     /locus_tag="L1V17_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HBN1237290.1"
                     /translation="MNKDITFPVMDVRLVPITKIQANDYNPNRVASPEMNLLELSIIE
                     DGFTQPLVCYYKEKEEKYILVDVLHRYRVAKERLNLKVVPVTVIDKPIEERMASTIRH
                     NRARGTHEIRGMEIVIQRLVKNGWSDKRISKELGMDIEEIFRFKQVS"
BASE COUNT         2594 a         1336 c         1460 g         2732 t
ORIGIN      
        1 taataaagac acgtaaatca attatttttc attttacttt aactaataat gtttatttgg
       61 agggattatt atgttagatg atagattgac gtgttctaat tgtggtacat tattttacta
      121 tgaggaagtt agaaatattg taaaacatag aaaaaaagaa atgcctatac gttgtccaaa
      181 ttgcaatgaa gttattaagc gaaagttgtc tcatggttat tttgtcagct acgaactata
      241 tgaagaaagt aaaataaatc tgaaaaaaaa accaaaatac tataaaaatt tgaaaactgg
      301 agctattata actgaaaaag aatttaaaaa tttagtgact gaagaagaaa gcaggtttta
      361 taatttgtct ggtaatattt gccctggatt tatggatcag attattgaaa atgagtcaat
      421 tgaatcaatt gaaaactatg ttcctgttga cttaccaaaa tagaaaaaat aatcctgttt
      481 ttacagtgaa ttattttaat tttgattttc aataaaaata tattacaata ataatcgtaa
      541 tagctaatga aacaatttct caatcttttt accactccaa acagggagcg tcaataattt
      601 tgtgtaaata actcgtcctt ctgcaaaata atgggttact cagtaaacat tgaagctaat
      661 gtatccgtca cttgttggaa gcctttatgg cttctattta agaatttttg attgtatgta
      721 tcaaagatgg atactaggaa acgctctagt gattcttcat tttgaaactg ctcttttctg
      781 cggctgtatt tcttgatttg tttattgaaa gattcgattg tagaaccaga aggaatggag
      841 aacacttttg aactttacaa caaaactact gttgataaat taattccaat tttagttcca
      901 actgatttaa atggtcatga tgttttactt cgttttaacg gatttttagg tgaggattat
      961 agatacctaa aaatttctga tcctcaacct ttaacagaat aataaaaaac gtgtaatcaa
     1021 ttatttgatt acacgttttt tatttcaatc ttcgttgtag tagtggttgc gacataccga
     1081 aaggtaatct tcattacctc ctactacaat ctgttcacct gaataaactg gaataccatc
     1141 aacaatacga gcattcatta cagccttttt attgcaaaaa tggcaaatag ttttaatttc
     1201 ctcaatttta tcagcaaatg tcaataatgc ttcggatccc ttgaagagat tattttgaaa
     1261 atcattcttc aatccatagc aaattactgg tacttcctca ttcattacga taagtgatag
     1321 atcaataata ttctctctac ttaaaaattg agactcatcg accaaaatac aatcaacttt
     1381 tccgtactga tcaataatct ccactaattc tccgtacaca tccatttcag aagtaattgc
     1441 aatagctggt ttcgaaacac ctatacgact ctcaactttt ccaaatcctg atcgagtatc
     1501 tattgcgctt gtcattatga taactctctt cccttgttct tcataattat gagccacttt
     1561 cagtagctca atactctttc cactattcat tgttccatat ctgtaaaata attgtgccat
     1621 taaatttatt cccttctttt acaattcaat tattccttaa ttccatctgc ttttatgcag
     1681 ctgctcgttt attccttgat atgtctataa catctactat ccctaaaacc aatttataag
     1741 ccattagaga tggtattcct gaacatctct catattgttt tttgagtggt atatcatctg
     1801 aaaaactgaa ggaatcatga aaatagcgac atacttatca tttagagttc taactttaaa
     1861 tgcatttact tcttcagtca gcactttagt catgttggac atggtttggg gcgtgtagtg
     1921 atgcccatac attttctcaa tcaagtctgc gatttccgac atggtaatac cttttcggaa
     1981 gaggtgaatg acggtctcct ctaatgtgtc attcgtccgt ctataagcag gaacagtctg
     2041 ttgcttgaac tcgccattgc ggtcgcgcgg aatctggaga tgaagttccc catactcggt
     2101 cttgaccgta cggtcatagg agccgttacg agaattaccc gtgttaaaac caatgcgatc
     2161 gtacttttcg taatcgagga aagccgttaa ctccgttttg agaagcgtat tgacagcttt
     2221 ttccaaatgg acacggaata atccattcaa atcgcctttg ttcgctagag tctttaggat
     2281 ttctgtagta aaatcgttca tatggaagtc ctcttttctg tgaatgtgtt gtggtaactc
     2341 tattctacag aagggacttc cttttttcta tttacacaaa atattttaca ctctcaacaa
     2401 aagtatcttc gattaatact tgctcaagtt atgtgcagct acgaaaaagt aggtaccgag
     2461 gtactttctt tttcgcagct ttttttggac ttatgagaag tacattcgct ggaagaatac
     2521 gatataaaac gagctttttc actaaagata ttaatagagt gaaagaaaca agcttttgtt
     2581 gtcagttttt tcacttttct aaaaatgaaa ataaaaaatt ctggaagtgg agaagaattt
     2641 tgcttgctat actttgtctt gtagaaaaga ggtagacaaa ataatgcaag ctcaaataag
     2701 cgattttcca taaccttggt aggaatgaca aattaaatag gaaagggaag taataatatg
     2761 aataaaaaaa agttatctct attcggtttt tttgccctga cagcttccat ggttttgact
     2821 gtttatgagt atccgacctt tgcaacatca caattacatt tggttttctt tcttcttttg
     2881 ggaggtattt tatggtttct accagttgct ttatgtgctg cagaaatggc aacagttgaa
     2941 ggatggaaag atggtgggat tttcagttgg gttagtcaaa ctttaggaga acgttttggt
     3001 tttgcagcta tttttttcca atggtttcaa attacagtag gttttattac aatgatctac
     3061 ttcatactag gagcgctgtc gtatgtaatt aattttccag agcttaatac agatccattt
     3121 atcaagttta ttggtgtatt agtcattttc tgggtactga ctttttcaca gttgggcggg
     3181 accaatcgta ccgctaaaat tgctaaagca ggatttgtca ttggaattgt tattccttcg
     3241 atcattctct ttggtttagc agcagcctac tttatcggcg gtaatccgat tcaaatggct
     3301 attaatgcga aagcttttat tcctgacttt tctcagcttt caactttagt agtatttgta
     3361 tcttttatat tggcttatat gggcgtagaa gcttcagcat cacatattaa tgagctggaa
     3421 aatccccaaa gaaactaccc attggcaatg tttttactag tgattttggc catcgcctta
     3481 gatgcaatcg gcggtttctc agtagcagcg gttattccac aacatgactt gtctctcagt
     3541 gctggtgtaa tccaaacatt tgaaacgctt attttacatt ttaacagtca tttacattgg
     3601 ttggtaaaag tgattgctct catgattgcc tgtggcgtta tgggtgaagt tagttcttgg
     3661 gtagttggtc catcacgagg gatgtttgca gctgctcagc gaggtctgtt accagttttc
     3721 ttccggaaaa ctaataaaca agacgttcca gttccgttga ttatgataca aggaattatc
     3781 gttactattt gggcagcagt cttaactttt ggtggaggag gcaacaattt atcattctta
     3841 gtagcaatct ccttaactgt tgtcatttat ctcgtaggat atttactatt tttcctaggt
     3901 tactttgtat tagtttttaa gaaaaaagac ttaaaacgaa cttacaatgt accaggaaaa
     3961 actgttggca aaacgattat cggtggaatt ggttttattt tatcagtgtt cgcattgctt
     4021 atctcttttg taccaccagc ttcaattgca gctagtgagc accgaacata ccaaatcata
     4081 ctacttatta gctttgtagt gactgttctt ttacctttta tcatttatga agtacatgat
     4141 aaaagtgctc acacaactat tgaggaacct actcacgtga aagctgaaga cgttaatccc
     4201 gctgtttatc cagctgctag aggagagcac cacgttacaa aaaatgatga acatatttta
     4261 aaacattagg aggaattcat tatgttatac ggaaaagata atcaagaaga aaaaaactat
     4321 ttggaaccaa tttttggctc tgcaagtgag gatgttgact tgcctaaata taagttaaac
     4381 aaagaatcca ttgaaccacg aattgcttat caattagtac aagacgagat gttggatgaa
     4441 ggaaatgcgc gattaaactt agctactttt tgtcaaacgt atatggaacc tgaagcagtg
     4501 aaattgatga cccaaacgtt agaaaaaaat gcaattgata aatcagaata cccacgaaca
     4561 acggaaattg aaaaccgctg tgtaaatatg attgctgatt tatggcatgc tccaaataat
     4621 gaaaaattca tgggaacttc aacgatcggc tcttcagaag cctgcatgct gggtggtatg
     4681 gccatgaaat ttgcttggcg taaacgtgct gaaaaattag gtcttgatat tcaagcaaaa
     4741 aaacctaacc tggtgatctc ttctggttac caagtttgtt gggaaaaatt ctgtgtatat
     4801 tgggatgtgg aactgagaga agtcccaatg gatgaaaaac atatgtcaat taatctagat
     4861 actgtcatgg attatgtgga tgagtacaca attggtattg taggtattat gggtattact
     4921 tacactggtc gttatgatga tatcaagggt ctgaatgatt tagttgaagc tcacaataaa
     4981 caaactgact ataaagtata cattcatgtt gacgctgcat cgggtggctt ttatgcacca
     5041 tttactgaac ctgatctagt ttgggatttt caattgaaaa atgttatctc aattaattct
     5101 tcaggtcaca aatatggttt ggtatatcca ggtgtgggtt gggtcttatg gcgtgaccaa
     5161 caatacttac cagaagaatt agtatttaaa gttagttact taggtggaga aatgccaact
     5221 atggctatca acttctctca tagtgcagca caactaattg ggcaatacta caactttgta
     5281 cgctatggct ttgatggtta tcgtgatatt caccaaagaa ctcatgatgt tgctgtttat
     5341 ttagccaaag agatcgaaaa aactggtatt tttgaaatca ttaatgatgg atcagaattg
     5401 ccagttgtgt gctataagct gaaagaagat cccaatcgcg aatggacact atatgattta
     5461 tctgatcgtc tgttaatgaa gggatggcaa gtcccagcct acccattacc taaagacttg
     5521 gatcaattaa ttattcaacg cttagttgtt cgagcagact ttggaatgaa catggctggt
     5581 gattatgtac aagatatgaa ccaagcaatt gaagagttga ataaagctca tattgtttat
     5641 cataaaaaac aggatgtgaa aacgtacggc tttactcact aaaattcttc agagaaatat
     5701 aaaagaagtt aattaactaa taaaaggagt tgtgattacc acacagctcc ttaaatctat
     5761 ttgaataaat atatgatatt catttgttac actctcaatc ttagctgttg ttctattcat
     5821 cattactctt attgtaagta gttcagtcaa atttgcttgt tcaattgatc gataacagta
     5881 tgaattgttt gaaaagtaat cggatatata attgttttct cactacctaa gccttcttgg
     5941 tataaagaac tatcgcaaag tataatccgc tgagtacaaa agaaagtgtc gtctactatt
     6001 tctctaagtt gtttacaaat gatattacta atagaaaagt gttctcccaa aatgtcttct
     6061 aactgttgtc gatagtataa atacctaaag tctgacggag ctactatgaa cacttcaatt
     6121 ggagatttcc gtttatgctc atttaaaaga cttaaactaa tggttagttt acgaatagaa
     6181 ttctcattcc aacgcagaaa taaattgttt tgttttcgcc attgttcaag aatttcatga
     6241 acttctaagt acaaagcgcg ttgctcttca tttaacaagt aagtcttatc aggttgaaat
     6301 atctgaatat cagcccaaag tgagcggata aacgggagaa gtgctttatc aaaaagtatc
     6361 tgattttctt cagatatatt cagagataag ataagttttt gactgagctc aatcaccaaa
     6421 gggttatctg ctacatggtt ttgataaaca acgttcaagt ctttttgtaa caattcaaag
     6481 ttatcgcata gataatttct agagttgaat agaaagtaga tataaaggca ttcatcttcg
     6541 tcatgacata aagagaaaga aagttgctct aatcctttct gtattagctg aaacaaggga
     6601 gtatgtcggg caactctttt ttcttcctga ctaaaatata ttgggttagt cttagatctc
     6661 tgcaaaccga tagcgatacc taataaaata aattgttttt caactgtagg gtaacttctt
     6721 gaaaaaaatg tttttctaca taatcaatca attgttgacc gctttgaata attgatttat
     6781 ttagctggat caactctgtc cgatttgtct catagattat cgttagtaac aaacttcgat
     6841 aatccttttc aggaatttca aaatggccat cagcatttaa gtactgcatt tgtttaaaaa
     6901 aattaatcaa ctcatttcgt aagttgtaaa ctttgcttaa cgaaatgaag gtagtatcag
     6961 ctatattact ccaattgtgt tcccctgata aataatgtcc tagtacattg aaaaagtcag
     7021 agcgctgata gatgagttga gtgagtgcca acctcgaaaa cgaagagtcg aatgcgactg
     7081 taaagctact tctagatttc tccactgaaa taatttgctg atggagtatg tcggtaatgc
     7141 attccaagtc gttagtgaca gtgagtgggc aaacgttcaa ttgatctgct atttcgcgaa
     7201 tctgaatggt ccctttttcg tgtaattgct cacaaatgta aacttgacga aaaatacttt
     7261 tctccagata ggtttccaac atagtactcc tcctagtcat tttatacata actattataa
     7321 ctctaccaat cggaatagtc ctgtaatata ttgaatcaaa aatataaatt ataaaataat
     7381 tagatggggt atttggttta agtatccctt atatagtaat aaatttatag gtgtgattct
     7441 cgaattaata cccgaaaatg tgagagaatt tttatggatt ttttaggata caaattaatt
     7501 atttttgctt ttatcctgat taccagtcca gtactgtcgg tatcccattt tgcagcaaaa
     7561 tcatgttgat aaagtgacaa gaagactgat gagatatatt atccaaattg agaagataat
     7621 taatcggatt cttgagtata ccctactttt taagaaagta gggtatacaa gcgtatgaat
     7681 aaagacataa ctttccctgt gatggacgtt cggcttgttc caattaccaa aatacaggcg
     7741 aacgattata atcccaatcg agtagcgtct ccggaaatga acttattgga gctttctatc
     7801 attgaagatg gctttactca accattagtt tgttattaca aggaaaaaga agagaagtat
     7861 atcttggttg atgtgcttca taggtatcgt gttgctaagg aaagactcaa cttaaaagtt
     7921 gtaccggtaa cagttattga taaacccata gaagaacgta tggcttcaac aattcgacac
     7981 aatcgtgcaa gagggaccca tgaaataaga ggaatggaaa ttgtcatcca aagattagta
     8041 aaaaatggat ggtcagacaa gagaatatcc aaagaattag gcatggacat tgaagaaatt
     8101 tttcgcttta agcaagtgtc tg
//
LOCUS       DAFLWC010000108         8073 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.111, whole genome shotgun sequence.
ACCESSION   DAFLWC010000108 DAFLWC010000000
VERSION     DAFLWC010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8073
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.111"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(84..932)
                     /locus_tag="L1V17_002583"
     CDS             complement(84..932)
                     /locus_tag="L1V17_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBN1237291.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(1156..3096)
                     /gene="thrS"
                     /locus_tag="L1V17_002584"
     CDS             complement(1156..3096)
                     /gene="thrS"
                     /locus_tag="L1V17_002584"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBN1237292.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3433..3612)
                     /locus_tag="L1V17_002585"
     CDS             complement(3433..3612)
                     /locus_tag="L1V17_002585"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HBN1237293.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3659..5482)
                     /gene="cadA"
                     /locus_tag="L1V17_002586"
     CDS             complement(3659..5482)
                     /gene="cadA"
                     /locus_tag="L1V17_002586"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBN1237294.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5760..8039
                     /locus_tag="L1V17_002587"
     CDS             5760..8039
                     /locus_tag="L1V17_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1237295.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
BASE COUNT         2368 a         1712 c         1462 g         2531 t
ORIGIN      
        1 gtgaaacact ttgatggatc atttatttgt ggaaaactac gttttgttat tctaaaaaac
       61 ttatataaaa aatagtaagg tttttatttc gaatccataa aatattcttg gattgcttct
      121 cgtgtttttt tcactttttc gctaagcttt tcgtttttag ccatatagaa ataaaaaatg
      181 atatcgatcg tagcaaattg ggccaaaagt gaattagttg ccgcacttcg attcgtgatt
      241 tcttttggtc tagatgtttg tacgagtaca tcggctatct tgctaagcgg gttatttcca
      301 aattgcgtca acgcaatgat ttcgatattc atgcttttcg ccagctcggc taatgcgact
      361 acatctgcac ttctacctga gtttgaaaca agccaaagca ctttcttttt ctcattgctg
      421 acaagttgcg ggagcaagac gtggatatct ttttcaaaaa tgattggctt accgacacga
      481 gaccattttt gcagaatatc ttctactact aaagaagagg cgccaacccc atataaaaaa
      541 acagtctctg ccgattccaa acactctacg actttttgga tcgtttcttc ttctagaata
      601 tctactgttt cttttatcgc tacttgtgca ttgttaccaa gtttgttttt gatagagtaa
      661 aaggactcat ttgcttctat atcactaaaa ccttcatcga ttccagtctg tagttctgtt
      721 gaaatcgtga ttttgaagtc cgtcagactt tgaaaaccga tttttttgga aaaacgtaca
      781 actgtcggcg cactcaaccc ggaagcttct gctaattcat tagctgtcat tgtagggacc
      841 ttctcaatat taccgataat gtagttggcc aacttttttt ctgctgaaga ataatcttcc
      901 atcatacttt caatacgact aattacgctc ataagttcct ccaccctttt aatgatagtc
      961 tatgtaagta taccatatca gacccttatt cacggtcgta tactggataa aaaacaaaaa
     1021 aacaatccgc ccaacagaat atcttatccc atcaatccca cagattctat tgagcatctg
     1081 tgtctttgag gaatacctgt tatctattgt tcggattgct ttctatctac tactttttta
     1141 caggaaattt acctattagt tttctctgct gtaatttttg acttctgctt ccatagcatc
     1201 aataaagata ttcaaatctt ctacagctgt ttctttactt ccataacgac gtacgttcac
     1261 tgttgcatct tccaattcct tgtctccaac aactaattgg taagggatct tttgtgtttg
     1321 agaggcacgt atcttatagc ccattttttc attacgatca tcaacttcta cacgcaaccc
     1381 cttcatttgc aaacgttctt tgatttcata agcataatcg ccatgtgcat caacagaaac
     1441 agggatgatt gttgcttgta taggtgccaa ccatgttgga aaagcgcctt tgtatacttc
     1501 tgttaaataa gcgacaaaac gttccattgt agaaacaatt ccgcggtgga taactactgg
     1561 acgatgcgta ttttccccgt cttctccaac atatgtcaaa tcaaagcgct ctggcaataa
     1621 gaagtctaat tgtatagttg ataatgtttc ttctgtacca agagctgttt tgacttgaac
     1681 atctagtttt ggtccgtaaa aggctgcctc gccttctgct tcaaagtaat ctagttctaa
     1741 ttcatccata gcggctttca gcattgcttg ggctttttcc cacattgcgt catcatcaaa
     1801 atatttatct gtattgtttg gatcgcgata gctcaagcgg aaacgataat ctgtaatatt
     1861 gaagtcagca tatactgcca ccatcaattc aagcgtacgt ttaaattcat ctttgatttg
     1921 atcaggacga acaaatgtat gaccatcatt caacgtcatt tctcgtacac gttgtaaacc
     1981 tgacaaagca cctgattttt catagcgatg catcattcct aattcagcga tacgaattgg
     2041 taattcacga taagaatgga tcgtgttttt gtagaccatc atgtgatgag ggcagttcat
     2101 tgggcgaaga acaagcattt cgccatctcc catatccatt ggcgggaaca tgtcttcttg
     2161 ataatgatcc cagtgtccag atgttttgta caactcaaca tctcccatta ttggtgtata
     2221 tacatgttgg taacctagac taacttcttt gtctacgata taacgttcga tcgtgcgtcg
     2281 gattgttgcc ccttttggaa gccagaatgg caaaccagaa cctacttctg gggaaaccat
     2341 gaacaagtca agttcttttc ctagtttacg atggtctctt tcttttgctt cttcacggag
     2401 acggatatat tctttcaaag ctttcttgtc aaaaaaggct gtcccgtata cacgttgcat
     2461 catttgattg tttgagtttc cacgccaata agcacctgcc actgataata atttaaatac
     2521 ttgtatacgg ccagtggatg gaacatgtgg tccacgacac aaatcgatga attcgccttg
     2581 ttgataagca gtaatcactt cttcttctgg caattcacta atcagttcta ctttgtacgg
     2641 atcacttgca aaaatttcta atgcttcctg ttttgaaaga acacggcgtt cgatcggcag
     2701 attttctttg acgattttca tcatttctgc ttcgattgcc ggcaaatctt ctgcagttac
     2761 ttggttttgt ccattatctg tatcgtagta aaaccctgaa tcgatagctg gtccaacgcc
     2821 aaagtggata tttggataga ggcgacgcat ggcttgggcc atcaaatgag ctgctgaatg
     2881 acggactaag ccaagtgcat cttcatggtc tggtgtgatg atctcaatac ttgcatcttc
     2941 ctcgattgga cgagtcaaat caacgagttt tccgttcact ttaccagcta aagctttttt
     3001 tgctaagctt tttgaaatgc tttcagcaat tgccaatgtt gttgttccag actcaaattc
     3061 tttgactgca ccatctggaa aagtaatttt tatcataata gtttcctcct tgaaatgttt
     3121 tgattgatca gatcatcaag ctgaaaaaca aaaaaatcct agcatctctt gaaaagagat
     3181 actaggacga aaagttcgtg gttccaccta atgttcaaac gcaaatgcgt tcctcaagcg
     3241 ttgtaacggt ccgaccgccc ttgcttcaac aagggtttcg aaagtggtca tcctttggtt
     3301 ttctcctgga aaagtttcag cctagctttt cctctcttat cgaagactct caaattcagt
     3361 tggctttctc atcaatcaat tatgtgttta tttaaccact aataaataga aaaatcaagt
     3421 gggaaactaa acttattttt tccattcccc atttacaccg tatgttcctt ttttcatctc
     3481 attgatgatg acatggatgt gttcttttgg tgcctgcgtg tttttatgaa cagcttccgt
     3541 gatatctttc atcatatttt ctaattgttc cggactgcga ccttctacta attcgacatg
     3601 tacgaatggc ataatgctct ctcctctttc tgatcgttct tttttcaact cgattctatc
     3661 atactatgtt tgtcttgggt actgaatcag gaaaaatggc tggatctttt tttgctctca
     3721 aggcactcaa aatagagacc gtatccacga cttcttgcaa aacagctccg aataatgcgg
     3781 ggattagtcc cgtacttgca attaacatca aaaaaataca aataaagatg ccaatcagta
     3841 cagactgttt cgctattctc atcgtatctc ttgaaatcac tactgctttt gctacacgca
     3901 agagatcatc tttcaagatg accgcatctg cactttcact agcagctgta gaaccatgag
     3961 cccccattgc aataccgata tctgcagcag caagtgctgg tgcgtcattc acgccgtctc
     4021 ctaccatcgc aacaggtctt tgatctttag ggatactttc taaaatggtc agtttatctt
     4081 gaggcaagct acgggcatgt acagaatcta attggacttt ttctgcaatc gtttgagcaa
     4141 tggcagatcc atccccggtg atcatcatca aatttttcac atcaagtttt cttagctcct
     4201 tgattgtctt tgctgcttct gggcgaatct gatccgaaaa taggatcgtt cctgcaaaag
     4261 atcgatcaat tgttacatag attgctgtat tggacgtttc tatttcttca gctgaaacaa
     4321 aagaggcacg tccaatcttt acttcatgat tattgactac tgcttggatt ccttgaccgg
     4381 tcacttcttt cagttgacta acaggataca gttggctgtt tttcacgttg ttcactaacg
     4441 aacgagctaa gatatggcta gattcctgtt ctgcactagc tgcatacaga agtagctctt
     4501 ctttttttat tccattgact ggctgaatcg cctctacttc caatatccct ttggtaagcg
     4561 ttcctgtttt atcaaaagca atcgtttttg tacgtgcgag cttttcaatc gttgttccag
     4621 tttttacaac gatcccgttt ttacttgaac ggctcattcc tgcaactaaa gcaatgggcg
     4681 cagctagaat cagtggacaa ggtgatgcca ctaccagtac ctcagcaaat cgtaaagggt
     4741 cttttgagaa ccaccaagaa ataccaccga tcaaataagc aatcaacgtg aaagggactg
     4801 cataacgatc agctaaacgg acaaatcggg caggcttttc ttttgattct tcgactagtt
     4861 taataatcat ttgatactgg ctgtctgcgg cacgtttttc agcgatcatt tggatcgatc
     4921 cgtctccatt taaagaccct gacataatct gatctccagg tttcttggtt tccgggcggg
     4981 actcacctgt caaagaagat tcatcgaccg aagattctcc tttggtcact cgaccatctg
     5041 cgggtacaag ttcgccaggc ttgactagta actggtcatc aatatttatt tcatcgatta
     5101 ctatatcctg caattttcct tctttgaatc gatgggcaat tcttggggtg ttatctaaca
     5161 aagactgcag ttctttaccc gctcgtttat tcgcgtaatc ctctagacta tctccgcccg
     5221 taagcatgat caatatcatc aaactagccc agtattcttt gacggctaat gttgcaagga
     5281 ttgcggtaat cgctaataca tctacgccat atcttcctga acgtaacgtc ttgatcattt
     5341 ccaaaaacat caagaaggcg agaatccctc cagtaaatgc gacaatcgca aatgcaaggg
     5401 ccggctggtg aaaaacaaat tcacttaata aagctatccc accaataagc aaagtaagta
     5461 aaaatttttt gaaatgtgtc attgtttttt ctcctctttt atgtgactta gagaggttag
     5521 taataaattt ccagctgcct ctttcatctt aagcatagtc cttgactagc actttttaaa
     5581 acaataggcc ttaattgaaa acaactatca ctatcagcgt ttccaaaatt catcagttct
     5641 acaaacaaaa atattcagca aggattactt tttcgattca tcagttaaaa agtacctttt
     5701 ttcgaaaaac tatgctatac ttttaattcg ttatttacgg cggaaggagc aaacatgcga
     5761 tgaatgagaa acaactagaa caaacgcacg tggatgaaac gatcgaacta atccagatcg
     5821 aacaaaatat gctggataca aaacaacaag aattgactca ggaaatgaat cattcgacaa
     5881 aagacacagc taatcacaag attcgagctg gttccaatga agctttttat gaatctgctg
     5941 ttgaatatcg ccaacatgag caggaattgc ttttgaaata ccatactctt gaagcacagc
     6001 aaaaacgcct gcaaacgttg tctgtcatga aagatagtcc ttattttgcc cgtatcgact
     6061 ttaaagaaga ccgtgaaaca gaaacattat atctaggtat cgcttcttta agagatctgg
     6121 cagaagaaac aatcgttatt gactggcgcg caccaattgc caatctttat tatgaaggtg
     6181 agattggtcc cgcattttat gaaactgaaa cagatagaat agatgtcgat ctgcagttga
     6241 aacgacaatt taaaatccaa gaaggacgta ttttatctat ggtagatacg tcggaagtaa
     6301 tcaatgatga ctttttgcta gagatattgg atgaatcatc aagcaaccat atgaaaaaca
     6361 tcgtctctac gatacaaaaa gcacaaaatg caatcattcg ggacacaaca agtaaagtaa
     6421 tgctgattga aggaatcgcc ggaagtggaa agacatccgc tttgcttcaa cgtattgctt
     6481 ttctgttgta tcataatcgc aagtggctcg aggctgaaaa cgttcttcta ttttcaccca
     6541 accatttgtt ttctgattac atctcgactg tattgccttc attaggtgaa agcggcgtgc
     6601 ctacacagac attcaaaaat tatttggtgc agctgctgcc agagttttct ttactagatg
     6661 aacagcaaca agaaagtggt tttttgctag gggaaaaaga tccgatacaa gtgatgaaaa
     6721 gcggattgac cttagtcgat cagattgatc gctatatcca aggcatcaca aactacggtc
     6781 ccttgttccg tgatatgaaa ataaatggcc gtacgatcct atcaaaggaa tcgattcgcc
     6841 aatggtataa agaaacaaat gaacaattac ctttacatca tagactttct ctattacaaa
     6901 cgaagctcct gaaaaaatta ggcggtctgc aaaaagacga aacacgtcag caatgggtca
     6961 aagatctggc ggaagaacag ctccaagaac tatacgcaac agatccaaat cttgaatata
     7021 cagaacaaaa ggagcgttca ttacgtaaaa aactggccaa ccaaatcgta cgtaaaagat
     7081 tccgtcgaat ccatcgaggg atcatgaatt atcaatttgt caatataacg aaacaatatc
     7141 tccactttct acaaactgtg ccactttctc ttctaacacg acataaaatc agcgagacca
     7201 ggtggcagga acatttgaca actgttcgta cacacttgcg tcaaagagaa ttgcgtcaag
     7261 aggatgctgt actattcttt ttactgatgc gccgaacata tccagtgacg gttacacaca
     7321 aagctcgcta tatctttatt gatgaaatgc aggatttcgc accatcacaa gtggcattgc
     7381 tgcaagcctt gttcccaaaa gcaaatttga ctttctgtgg agatctaaat caaaatgtct
     7441 ttggaaatga aacgatcgtt ggatcattgg aagacctttt cgtggaccgt gaagtcactc
     7501 gtttccaatt aacgacaagc tatcgctcca caaaagaaat cactgatttt gctaatcatt
     7561 ttattgtgaa agaacatcaa gtagaaacaa cagcaagaaa aggagacctt cctttgctca
     7621 tccaaggaac aacagatgat atcaaattga attggttagc agataccatt cgaacgactc
     7681 agggaaaagc ccggtattgg cgtacagcaa tcatagctaa aacacaagaa gaatgcgaag
     7741 ctctttatgc tcaactgcca gacgagttga aacaacaagt ccagctgatt ttaaatgaga
     7801 gtgactttat gaagcgttcc attattttac ttccagcctt tttagcaaaa ggtctggagt
     7861 ttgaccgagt tttcttgtgg gatgtagatg cagaacattt ttcttctcag caagacaaat
     7921 tgatccttta caccatgtgt acacgtgcga tgcatgaatt gacccttttt acctccaata
     7981 atgaaagtcc tttgttaaac aatatggata tttcatctta tgagaaaaaa gtactgtaag
     8041 taaaaagaca actgctatca ttaatgttag cag
//
LOCUS       DAFLWC010000109         7856 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.113, whole genome shotgun sequence.
ACCESSION   DAFLWC010000109 DAFLWC010000000
VERSION     DAFLWC010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7856
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.113"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            108..809
                     /locus_tag="L1V17_002588"
     CDS             108..809
                     /locus_tag="L1V17_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBN1237296.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(1418..2434)
                     /gene="tsaD"
                     /locus_tag="L1V17_002589"
     CDS             complement(1418..2434)
                     /gene="tsaD"
                     /locus_tag="L1V17_002589"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBN1237297.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(2431..2895)
                     /gene="rimI"
                     /locus_tag="L1V17_002590"
     CDS             complement(2431..2895)
                     /gene="rimI"
                     /locus_tag="L1V17_002590"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBN1237298.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(2902..3444)
                     /gene="rimI"
                     /locus_tag="L1V17_002591"
     CDS             complement(2902..3444)
                     /gene="rimI"
                     /locus_tag="L1V17_002591"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBN1237299.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(3428..4150)
                     /gene="tsaB"
                     /locus_tag="L1V17_002592"
     CDS             complement(3428..4150)
                     /gene="tsaB"
                     /locus_tag="L1V17_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBN1237300.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(4341..5321)
                     /locus_tag="L1V17_002593"
     CDS             complement(4341..5321)
                     /locus_tag="L1V17_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1237301.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(5345..6829)
                     /gene="galT"
                     /locus_tag="L1V17_002594"
     CDS             complement(5345..6829)
                     /gene="galT"
                     /locus_tag="L1V17_002594"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HBN1237302.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(6841..7830)
                     /gene="galE"
                     /locus_tag="L1V17_002595"
     CDS             complement(6841..7830)
                     /gene="galE"
                     /locus_tag="L1V17_002595"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBN1237303.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
BASE COUNT         2200 a         1695 c         1393 g         2568 t
ORIGIN      
        1 tttgtaaagt attaaaactt gtttctaatg ttggtatgtt aaaactttac aaattcttta
       61 aaaaaagtga caataaatat agtgaacaat aaggagagga ctttttaatg cgtgttaata
      121 aaatcgattt tcacttttca aaactcagat atcaacctga ttttgaacat ttctcggatg
      181 aagagttcca acagatcaag gaacatactg ttcttcgttc ttataaaaaa ggacagatcc
      241 ttttcgacga tggtgatccc agacaacggt tgtatatctt gaccaaagga ctcgttcgtt
      301 tagaacgtta tgatgaaagt gcaacttatt actactatga ctatgtgaat acaaataacc
      361 tttttcctat gtcaggaatg tttggagaag agacctacac ttatacagct caagcgatga
      421 ctgatattga aacattctac cttcctgttt cctactatga aaaattagca cgaaaaaatc
      481 ccgaacagtt gatctatatg atacaaaaaa tttctaaagt agttgaaata catgaattgc
      541 gtatccaaat cggattgacc tctagcgcct ttgaccgggt aaaacaaaat ttattcattt
      601 tgaaagaaga attgggcgta ccaacaaaag atggtcatat caccattcct tatccgatca
      661 ccttaaaaga attagcagtg aatagcggca cgacacgtga aactgctgga caagtaatca
      721 aacaactacg tgattccggg ctgttagatt atgacaaaaa gcgttttact ttctgtaaga
      781 cagctactac tccagctatg agagaataac gcgaacaaaa ataagcagtg accctgataa
      841 atatcagggt cactgcttat tttcctccct aaaacttctg aaagatccgg cagttttaga
      901 tcactggaca agactcaaag attttctatg tgtgtttcag ttatgtaata ttcactgttt
      961 gcaaaaaata ctgttagatt aactagatga agcgtcttgt cctcatccga tctagattat
     1021 tcgatattcc tcgacaataa acgattactc agtgagggca atcagaggaa cggataatga
     1081 taaataagct gtaaaaaata gcaaaataac aataatgatt aaaagtatgt aaaaaatagg
     1141 gctttgacaa aaacgtgtca cagccctatt tcgattaaac ggtgtgtacc tgtcaactct
     1201 tcggtcacaa gtcataatgt tcataaacat gaggagctgt tttttgaaat tgttccttgt
     1261 gaatcagagt taaacgacag gcttacgaac tcttgattaa acggcgttca aaagcttgca
     1321 tacgcggtaa taagaacagc caggtcaaaa acatgagaag ccgtttttcc tgggctgttc
     1381 ttattacttg atgcagggca gctttttcac aacctcttta ttcagataaa accaagcttg
     1441 gatcagcatt caactgatag ctagcaaaat ttcttttttg catttccaca tgtgctgctg
     1501 ctccaatcat tgcagcatta tctccacaaa gtcgaagagg gggaatcact agttctacct
     1561 cagggagttt agctgccaaa gcatcctgca atccttcacg caacccttga ttggccgcta
     1621 cacctccagc tataatcagt tgcttgactg gataattttg acaagctcga agtgttttag
     1681 taatcaatac atcgatcaca cttgcttgaa agctagctgc taaatcattt ttgtctagat
     1741 cttctccacg ctgttgtgca ttatgcacca aattgataaa tgcacttttt aatccgctaa
     1801 aactgaaatc ataattatct tcatggatca tcgctcgcgg aaaatggtaa ttatcttttc
     1861 cctgatgagc tagctgatcg atttcttttc cgcttgggta agaaagacct aatactcttc
     1921 caactttgtc ataagcttct cctgctgcgt catctcttgt ctccccaatg atttcatatg
     1981 atccatcttc ttgcatatag actaattctg tatgtcctcc gctaacaaga agtgccatca
     2041 atggaaactg gaatggttta accagacggg ctgcatagat atgccctgcc atatggttta
     2101 caggaataag cggcaattgg tgtgcccaag caaaagcctt agctgcagaa ataccaatca
     2161 gcaacgagcc gacaagtcct ggtccataag tgacagcgac tgccgataaa tcttctgccg
     2221 acacaccagc ttctaccagt gcatcttcca agcataaggt gatttgttct acgtgatggc
     2281 ggctagctac ttcaggtact acgccaccaa aacgtttatg actgtttatt tgagaagcaa
     2341 cgatgttaga taagatctct gttccatttc taacgaccgc tacactcgtt tcatcacaac
     2401 ttgattcaat cgccagaatc aattcttcat tcatttcatc gtctccgttt ttaactttct
     2461 gctcataatg atcgcatctt ccgtcggatt gcgataatat gatttccgtt tacctaatat
     2521 acgaaacttt tctgattcat aaagttttct tgctgcttca ttagatagac gtacttctaa
     2581 aaaaacatgc agcgaatctt ttatttgttc cgtaatcagt aattgtaaca aatgccgtgc
     2641 atgccctttt ccttgttctg aaactgcaac agcaatattt gtgatctcga cttcatctat
     2701 tactttcgag tatccaataa agccacagat ctggttatct tcagctaaaa gcagataatc
     2761 agagtgaggc tgttggatgt ctgccaaaaa ctgcattttc gtccaaggtg aaccatgtgg
     2821 ataagcattt tcgctaatca tccatacgca ttctgccaag tacgcttcat caaaatcttt
     2881 ttttctgcaa atcaactaat ctcactcatt ttctaaaagt tttatcatat ccaacgcatc
     2941 ttcttttgtt tcagtgtaat atcttttttt gatcgttgtt gcttgaaacc ccaatttccg
     3001 ataaagtctt tgtgcatctt gattactcat acgcacttct aatgacatcg tctcacagcg
     3061 attcattata gcaaagttct cgatttcgtc aataagcagc gaaccgattc gtttacgctg
     3121 atatgccggt cgaacggcaa tattcgtgat atggcaatct aaaccgaacg ctcttgaacc
     3181 gataaaacca atcattcttc cattatcaaa gatacctaga tatagatgag gaagcggtga
     3241 cttcaattct gatataaagg cactttttgt ccatggcaat tcgccattat agacttctcg
     3301 ttcgacatcc agcagctctt tgatatcttc tgtagtcaat tctcttagta cgtaacgacg
     3361 atcgatttgt tcgactgttt tttctgtata aatcatttta tcttgaaaaa agcttctggc
     3421 atacgctcta aattttttca acataacttt cgtctccagg tgtgtgcgtc tccaaccatt
     3481 tttcttctgc ttctactcgt tttaaatagc gaggaagaaa agcttgtttc tctgcaactg
     3541 gttcaactaa agcacctaat tgagccacag ttacaccact tggaatatcc catgctggaa
     3601 ctgtattaat catcgcacta ggcaatattt cctttatttc agagaagaat ttgtgacaat
     3661 cactcccgac gaaataaata gcttcattca gcttttgtag ttgtgtgaac aaatcagaag
     3721 cagaaatatg tacatcttca agtacagttt ctaatctatt ttctttccag cggtatgccc
     3781 cagcgtatac attttttctt cgagcatcaa acatgggcac aataatatta tccacaccga
     3841 tgcaattagc cgcgatggtt ttcagactag atactcctac tagctcttta tctaatgtat
     3901 aagcaatcgt ttttgctgtc gttacaccta tacgaagccc tgtataagaa ccgggaccat
     3961 cagaaaccgc gattcggtca atgtcttttg gacttatttg aagatctgca aacaattggt
     4021 cgattgcagg catcagtgtt acactgtggt tgcgtttgat atttgtttgt atttgtccaa
     4081 gaatttgttc gtcttctacc acaccgatcg ccaaagtttg gtttgcagta tctattccta
     4141 atgtaatcat atatttgatc ctttctgcta tgacattctc gccttccatt gtagcatact
     4201 tttttattct gaggatgaaa ataccaaagg caaaactagt acaataatac atgattatct
     4261 gctggcgggc aaattttgcc ccttcctgaa acacaaaaaa gctgcggtat cactccattt
     4321 tcccacagct tttccatctt ttatttcgtt gattctcgaa taatcaactc tgtttccaca
     4381 ataatctttc ttgaaaccgg tgctttggaa ttacttaatt gaagaatcgt ctccactgct
     4441 agctctccca tccattcggt ataaactttt acagtagaaa gcgagggcgt tacatatttc
     4501 gctacactga catcattgaa gcccatcaca gaaatatctt ctggtaccac taaacctttt
     4561 tcttgaatcg ctttcagtgc gccaatcgct aatgcatcat tagctgcaaa aagcgcatca
     4621 ggaacatgcg gattcgtttt taaatattgc ttcactgctt gatatcctga ctcgacagaa
     4681 aaatctgctt cgataattgg accttcgtcg tagccttttt ctgccaaaac ttgttgaaat
     4741 gccataattc tgggatcttt tagccgctga tggtttttct tcgtatattc tgttccagca
     4801 agcatagcga tatgttgcgc tttatgggag acaaagtgtt caatgacttt ttgaacactt
     4861 gacttaaagt cgacaactag agagtcgatt ccttgagaag tgccgtcaga atctaccaaa
     4921 agcaaggcat tttgggatcc tttcatttct aataactgag cttcgtcgaa ttttcctagt
     4981 gcgatcgttc catctgccgg aagatcacta atggaatccc acgtttcttt caataaagta
     5041 acgtttgctt cttctgcctt tttttcgatt cctaggcgaa tagataaata ataaagatct
     5101 tcaagctctt ccgtatcgtc gtaccactgg atcaggcgaa gcgtttgctt agtatttgct
     5161 gcatttttac gatgtttcgt ataatttaag cgttctgctg cttcaaaaat tttttgcttt
     5221 gtggctaagc caacggaaag atcaggatca tagttgagaa ctcttgaaac agtagcagga
     5281 gaaactcctg ccaactgcgc aatgtcttta attgttgcca tttgtctctc ctcctttttt
     5341 acgtttataa aatcgcagta aatcgttcaa acgctgcctg tcctttttca tctcgcttga
     5401 atactccagc gtcttccagt acacgtgcaa aaacctgacc tacagatttt tgtacgacat
     5461 cggtgaccgt atctttcgtc aaatcaggat gttctttttt taattgttct gcccacggac
     5521 gatgatattc agccatctgg ttttcttctc ctaataagaa atgctctact tctactagtt
     5581 ctggtttcaa acgaggtggt aaaacagcaa gccccattac ttcgatcaac ccaatgttct
     5641 cctttttgat atgttggaca tctttatgtg gatgaaaaat cccatcagga tgttcttctg
     5701 aaacattgtt gtctcgaagg acaaggtcca actcaaagta attgtccctt cttcgtgcaa
     5761 ttggcgtaat cgtatggtgt ggtgtaccat ctgctgaaaa agctctgata gatactgttt
     5821 catccgaata tgctttccat ttttccaata ctgagttagc tgcttcaata agcaagtttt
     5881 tctctgttga ttgcaaacgg atcacagaca tcggccattt cacgactcct gcgatgactt
     5941 gcggataatc ttctagtttg ataagttttt ctatcggtgc ttttgccata ggaaattcat
     6001 gacgtcctgc ctgataatga tcatgagaaa gaatcgatcc tccaacaatt ggtaagtcag
     6061 cattcgaacc aacaaagtaa tgaggcaaga cttcagtaat ccgaagcagt ctagcaaatg
     6121 tttcctttgt gattttcatc gggcggtgtt gttctgataa aatgatcgaa tgttcattgt
     6181 aataagcata aggggaatat tggaatcccc agctttcacc gtctagattc attcgaataa
     6241 tccggtgatt ggtgcgggct ggatagttca agcgacctct atatccttcg ttttccatgc
     6301 aaagcatgca ggtaggatag tctactttta ccgcctcgcg ttctgctgcg atttgttttg
     6361 gatctttttc tggcttagat aaattgattg tgatttccag ttcaccatac tccgactctg
     6421 ccggaaattt gatgtttttt gcgatggctc ttgttttgat gtagtcattt ttcttactta
     6481 aattaaagaa atactcagtt gcttcctctg ggcttttcga atagtgctgt gcaaagaatg
     6541 cattgacgac tgaaggtggc ggtgtgagaa aatccattaa ttgcgcttca aaaatctctt
     6601 gttctgctgg caattctgaa agaacaccat tttctcttgc cttagcgaca agctgatcca
     6661 ataagtctac agattcttcc ttaactggtc ttacttcaat gctttctaga gcatcttctc
     6721 ctaccatccc taaaagacga ttctgtaaat ataagcggtc catttccatc catccgccag
     6781 cttcgatcgc aagtgtggca aaatcacaaa tcgtttgact gattgacata tctcattccc
     6841 ctattcttca taaccatttg gatggctgac atgccaatcc catgctgttt tgataatcgc
     6901 tttgatatct gtgtattcag gtttccagcc cagaatctct ctcgcttttt cacttgaagc
     6961 gactaatcgg ctaggatctc cagctcttct tggtgctatt tctgctggaa tttcttttcc
     7021 tgtcacttct ctagctgctt ctagcatttc cttgactgag tatcctttgc tgctgcctaa
     7081 attgaagaag ttgctttcat ttccttcttt caagtattcc aaagctaaaa tatgtgcagc
     7141 aatcaaatct tctacttgaa cataatctct gatacatgtt ccatctggtg tatcataatc
     7201 gtctccataa acagccaagg cttttctttg accaagagct acttgtaaaa tgattgggac
     7261 aagatgcgtt tctggtgtat gatcttctcc gatagatgca tctgcttttg ctccggctac
     7321 attgaagtag cgcaaagcga catagcgcat gccatatgct tggtcacacc acttcatcat
     7381 tttttccatc atcaatttac tttcaccata cggattttta ggattagctg gtgtatcttc
     7441 tgtgattgga gactctttcg gctctccata agttgctgca gtagaagaga atacgatttt
     7501 attcacgttg aactcgtgca tgacttcaag taagatttgc ataccgtata cgttgttgtt
     7561 gaaatacatc aatggttttt cgacagattc tcctactaaa gagcttgcag caaaatggat
     7621 tactccttca atcggttcct tttcaaatac ggaacgtaga aattctttat cccggatgtc
     7681 tccttcataa aaatgagcat ctggatgtac tgcttgtttg tgacctgtga gcaaattatc
     7741 taccacagct acttgatacc ccttttgaac tagctggtct acagcgtgcg aaccgatata
     7801 accggctccg cctagtacta aaattgtcat aaaaaacact cctttgatta gtaaaa
//
LOCUS       DAFLWC010000110         7811 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.114, whole genome shotgun sequence.
ACCESSION   DAFLWC010000110 DAFLWC010000000
VERSION     DAFLWC010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7811
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.114"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(31..1383)
                     /gene="celB"
                     /locus_tag="L1V17_002596"
     CDS             complement(31..1383)
                     /gene="celB"
                     /locus_tag="L1V17_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBN1237304.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(1383..1901)
                     /locus_tag="L1V17_002597"
     CDS             complement(1383..1901)
                     /locus_tag="L1V17_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237305.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(1917..2243)
                     /locus_tag="L1V17_002598"
     CDS             complement(1917..2243)
                     /locus_tag="L1V17_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HBN1237306.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(2256..4235)
                     /locus_tag="L1V17_002599"
     CDS             complement(2256..4235)
                     /locus_tag="L1V17_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBN1237307.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(4256..4570)
                     /locus_tag="L1V17_002600"
     CDS             complement(4256..4570)
                     /locus_tag="L1V17_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HBN1237308.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            4738..5031
                     /locus_tag="L1V17_002601"
     CDS             4738..5031
                     /locus_tag="L1V17_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBN1237309.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(5109..6221)
                     /locus_tag="L1V17_002602"
     CDS             complement(5109..6221)
                     /locus_tag="L1V17_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBN1237310.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            6608..6787
                     /locus_tag="L1V17_002603"
     CDS             6608..6787
                     /locus_tag="L1V17_002603"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237311.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            6981..7151
                     /locus_tag="L1V17_002604"
     CDS             6981..7151
                     /locus_tag="L1V17_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1237312.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(7575..>7811)
                     /locus_tag="L1V17_002605"
     CDS             complement(7575..>7811)
                     /locus_tag="L1V17_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBN1237313.1"
                     /translation="DATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKH
                     LPKTGETIISQFILSILGVLLVFISIKFRKKRNI"
BASE COUNT         2495 a         1554 c         1262 g         2500 t
ORIGIN      
        1 tttttgtcac agttcctttt ttcttagaaa tcattttaac ttttcactag ctaattctgc
       61 tgccttttct ctttcttcat ttaataattt attatcatag aatttgataa atgggaacca
      121 gataatgaat gcgatgattg cacaaatgac tgctaacaca gcagctttcc aatcaccacc
      181 actaccaaca aatgctccga tcccgactgg tgaaggccac ggcatctgtg caagcatcgg
      241 tttgacgatt tccagccgaa tggcaaaata agcgagtgta gcagaagcca tcggagctaa
      301 gaaaaacgga accgctaaat agggattgta gacgattggc atcccgaaaa tgattggttc
      361 attgatattg aataatcctg gtacaagtga ggcttttcct aacactttca gctgatcaga
      421 tttcgcgagg aatgcaataa agatgatcaa tcctaaagtc gcacctgatc caccaacggt
      481 tacataagaa ttgttgaatt ctcctgccaa cggataattt gcgccttgtg cgttagctgc
      541 catattagct aatacgatcg gggtcaagaa agaagtgatg atattcgctc catggatccc
      601 tacgatccac aatgcatgga tcaagaaata aatcaccatg acaccaagcc atgtattcgt
      661 caactgcgta acaaacccaa atgggatagc aatcattttg aagatatccg ttcctagtgc
      721 aactaataat ccattgatga tcatcaccac aaacgcaatg acaaatgttg ggatcagagc
      781 agtgaaagaa cgagaaactc ctggcggaac aacatctggc atttttatga cccaatttct
      841 cttgacacac atacaataca attcgaccgc aataatcgac ataataatag ctgtaaagat
      901 tcctgaagtt cctaaacgtt cgacaaaaga gcccatccta ataccattta ctacagtttc
      961 tgtctcattg atagaagcaa tcaagctgat tttaccatca gtcatgatca attcagggat
     1021 acacataaag aatgcaaaaa cagatagtaa tgcccccgtg agcggattaa catttaattt
     1081 ttgttcatct cgttcaattg acgttaattc ataagcaaac acaatggcaa agtaaataga
     1141 taaaatcccc atcgtcattg tattgacgat catgtacaag tcactaactt tgaaaaaagt
     1201 tgcattaaaa aatccttcta aaaatgggaa cggtaatggc aaaatattta aaaccaaaaa
     1261 catcgagcct acaatcgtga aaggaataga agccatcccc gctgccatga cagcccgaac
     1321 gattttaagt tgcgcaattt tccccatagg tcccatcagg tatttctgca aaaaatcaaa
     1381 cattagttat tctcctttcc taaatataac gctttttcat attgtttaat acggatatac
     1441 tgttggtctt ggttgagtga aattttcttt aaacgatact gtataaatgc actggcaaaa
     1501 ataccgctta caacaagaat gaaaacaaat aactgtcctc cattgttatt tgccataaaa
     1561 ggatacaaga atgtaaatcc tgaggtaaac aacactggaa tcactaataa attaaagaca
     1621 ctctggaaca aaaaatacca ctttgtccat ggaacgttcg tttggtgttt tcgataaagc
     1681 tttacttgtt ctcctactgc aggcaaaata gctaaaatca gaatcatcgg taaactactt
     1741 cctaaacttt tagctgatag aagcagaatc atccattgca tgttcatgaa aaagaaaaag
     1801 gcagtcaggt aacgtacgat tagataacga ttgaaataca tgtttttcaa actaagttgc
     1861 tttttttcta attcgatttt cctttttact gtatcctgca caatgatcct tcctttctat
     1921 ttattttttt gatacaaata attcatttcc tgtgcaactt ccaataatgt catcgtcgtc
     1981 atcagatgat cttgtgcatg gaccatgata atttccattt ctatttttgt cccgctggca
     2041 tattctttca gaagttgagt ttgtgactga tgcgcatgaa gaatctcttc atttgcttgt
     2101 cgcaacttct cttctacttc ttcaaacatc tctttacgca tcgagcgaaa tgcttcatgt
     2161 atcagtgtcc gtgcatttcc gctatggaaa atgatatcaa aagaagtcac ttgtagtgtt
     2221 tcactgttta ttttttcagc catctgtttt cctccttatt cgatcagttt gataaattta
     2281 ctgctgaaat tctcaaaaat aggttcagct aagatttcct gctgtacttt tagctggtca
     2341 actaacctaa cgattgcttt agtcacgacc gtaattcctt cattttcgac ataagaaggc
     2401 gaaactaaaa aaacaaaatg aatttcttga tattgatccc actgcatccc agaaggaatc
     2461 aatgcaacgg ctacctttgt ttcgattcca actggaacag cgggatgtgg gactgccact
     2521 gtatcactga atatgatttg tcccatattt tcacgttgct ggatctgctt tcgcatttct
     2581 cttatatatc cttcttcttc atttatgctc agcttttgca gcaaatcatg aagaatttct
     2641 tcctttttcg gttcgtacgt ataagtcttg aaaaattttt cagacaactg ttcggtgtaa
     2701 atctgctttt tttgctgtag agaaaatgct ggtatcggtc tatctgagga atgatagggt
     2761 atagattctc caactacctt tcgtatttta cgaacatcat cttcattcaa aaaaatactg
     2821 acatgtaaaa ctggaatttt gaaaaacatt gtcgaaagat caatagaaga aataatcagg
     2881 tcgattcctt ttaaagttgt ttcattgatc tcataatagc cttttacact taccactgta
     2941 atatttttac cgaattcact gactacgcga ttctttaata gttgggcact gccgtaaccc
     3001 gttgcacaga taatcaatgc atgtagttta tgcgcagctc tttctttttc caatgccgcc
     3061 atgagatgca aagccaaata ggcccattca tcttcattga tggtatagtt tttcaaagcc
     3121 ggcatgttgc tgaaatgcct ttttactgcg tcaaagactt tgggattttc tttctttatc
     3181 tcctcagtca atgggttctc aatgcgaata cctcggctca atcgaatcat catcggtgac
     3241 aaatgatcga gtagtccatt gaaaagctgg agatcctcta ctaatgaaaa atgaaattcc
     3301 tgagacaatc ttttcagaac tttcgctaat tcctttgata gttcctgatc attttgattt
     3361 tctttgtgat tcgacttagc catgagatgt aatgtcaaat aagcaatttc ttcttcggga
     3421 aacgatacac ctgcgattac ctcaatacgt tgaacgatcc gctgcgccac ttgatactct
     3481 actcgcttag aaacttcttg ttcgatgcct aattccttga tttcaaaccc ttctcggagc
     3541 cgtttgatcc ccaaagccaa gtgtaaagtc agattctgta tgataaaatc cgaaactttt
     3601 aacttagctt ctcttgtttc atcgagaatg ataatgacta gctcttcaaa actgatgtct
     3661 gggaaaaaac ggctttgccc taaatattct ttcaatgaat ttccataatg gtttccaaaa
     3721 aaagtatcca tgataaaatg ccgtcgattt ctttcttccc cttcgatcca tgtcccttga
     3781 ccatgcttag aaacgatttt tagtgaatat ggaatcaatc gctccttgat ttcttgcatg
     3841 tcctttgtca aactggaacg actgatataa agctcttctg ccaaatcatc cataaaaaga
     3901 atggcatctt ccaaaagcaa ttggttcaat atatactttt gtcgatcttc ggactcataa
     3961 aatccttgcg gttctctagc atatccaggt actatttctt gccgactcaa aaacaagtca
     4021 aatgtcagtc tttgtaaaat atgcagttgg tagccataac ctggtttagc aatgatctta
     4081 cctccgtttt tttctactaa ctctttgatc cgctgcaagt aattacggat tgtccgatca
     4141 gataataaca attcagaagc taaacgttga ctggtgacat actccttctt gtgatcaatc
     4201 aaatatctca acagcaattt ttccttctgt ttcattatca tccactccta ttccatcata
     4261 tgttctcttc gatcacctct gctaacttct ggatgcctgt agggattggg acatacgctt
     4321 ggaaagggat actaacaaca ggctttccaa cagattctcc taattttttg aatttatcca
     4381 aaaacatcgt cgtttgcggg ctgatcagaa ataaatcaaa atcactattc ttaatcatat
     4441 tatcgccttc tgtagctgaa actgcatcta cgagtacctc ttctcttttt tgcttaaaga
     4501 aatccgttgt ctttgaggcc atcatcgagg atgacattcc tgccgcacaa ataatcaatg
     4561 cttttttcat aaatcaatca ctccttttat ttttataaac caagcatatc ttgtaagcgt
     4621 tttctattca aaatatatat ttccgtagca ttgcggaaaa aatgtgtatc atatcttgaa
     4681 taataatttc tggcaccgtg atatactagt gatagaattt tttcaggagg ggatttagtg
     4741 agtatcacag tgaatatttt gtatacaagt acaaatggac aagccagaaa atttgcagaa
     4801 gaaatggtcg aaagaaacat tgtcaaagcg attcgtgcag aagaaggaaa cgagaaatat
     4861 gactattact ttccactaga agatccagaa tctcttttac tgatcgaccg ttggaaagat
     4921 gaagaagcaa tcgaaaagca tcacaaatcc gaaatgatgg ctcaaataaa cgaactccgt
     4981 aaaaagtata aattaaaaat gaaagtcgaa cgtttcactg atttaccgta aaaagataca
     5041 catggaatga tagcaattta tcatccatgt gtatcttcac tttttcctta ttttttattc
     5101 gatctcatct aatgattcaa accgtgtttt tctcttattt ttcggataag tatttcagtc
     5161 accccaatat acatgattcc taaacatacc ccaaggatat tctcaaaaat gcggatcgtt
     5221 actgctcctg gaaccccgaa taaactggca gtgattgcca aagcaccaaa agaattaaaa
     5281 actgttttat atctataggt agaacaaaca cctaaagcta gaccacctaa tataccgacc
     5341 cagttaaaag gaataaattg gctgatacca ataaataaaa cacatccaat caatgagcca
     5401 atgattcggt ctactgctcg ttctttgaaa ccaatcgaca tcaatccata gctagataca
     5461 atagaagaaa atgcaaaccc tgcccacatc aatcgctgaa aagggacata ctctcctgca
     5521 acgatcaaaa gactaatgcc aaatgcatag atgagcatcc aaattttttc ctgcgaatac
     5581 atgcctttca aaaaaatctc tttaaacaag cttttgtctt tgttcttttc tcgatgtttt
     5641 ctgtaaagga gaactgaaaa ccaacaaaaa aacaaaaata ataagctact tgtttgtgta
     5701 aagaaattct tgttcaacga atctttaggt aacgaataaa caataaagag atatgaaaag
     5761 ccgtacaaag aagcattccc cattttggga tcactagcgg ttgccattaa tatgctgctt
     5821 agtaaaataa aatgaatcaa catgcccata actgaccatt tgatcagctg gacatacggt
     5881 gctactaata gtgagaacat gacgattgct aaacctatga tcgaatggga aatcttataa
     5941 ccaaagtcaa caaaacgaat actcatcaac atacagaata aaaccacagc gtatggttta
     6001 tgcttcgatt caaataatgt tgtaattata atgataaaac aaatggcaaa caatacgatg
     6061 aataatgatc gtaaaaacaa tgaacaaata tacatgcact tttctttttt agaagctgct
     6121 tctcgtattt tttgttttaa aataaacgga tctagttgta gagactgata aaaatccacc
     6181 tgttgtcgtc ctttcttttt acttttattt tttacagtca tctatgacag gttgtaaata
     6241 ctatggaaca tcatatggcg ttgtcatttt cttgtcaact atttttccta ttcatgtttt
     6301 tataaaaaaa catatcgttt tcttgtatga ttaaatcacc acaaaataaa caactgagag
     6361 aacgatatgc tttatgaatg gttctatcaa aaaaattctg agatcaatag acaaaaattt
     6421 gatgattaca gaggtctctt acgaaacctt acagaagaaa aaaacattga tcgttgctgc
     6481 agttctcttc cctgctccat gtgtctgtag aaattgtggt tctgctgtgg tagatggaaa
     6541 taggaaatta atggtggtga aaaacaagaa gaaggaaacc attgtccact ttgaataata
     6601 taatcatatg ccaatggtta tacgcctaaa aaagcagcgc tatacctgta aaaactgtcg
     6661 aagccattgg aacgctcaaa gttattttat ccgtccaagg cactcgattt caaatcatgt
     6721 cagacataaa atcacttctt tactgactga aaaagtgtcg ttatttttta tttcgaaaag
     6781 ttgttaggta tctttgacaa ccgttattcg cacattgaaa gagttgagaa gctatttacc
     6841 aaagtcttcc aaaagaattc tgtcttgagt gttgagggtt gtgaatttcg ttctcacgtt
     6901 tccgttgagg ataaactgag ttttatttcc gcggatggcg agacagaaaa attaatcgag
     6961 aaaatttacc tacacaaaaa attcctcgat taacaaacta tttccttagc tgcactaatc
     7021 ctaaagaaat agaattctta gttacagaca tgaacgccac ctactttcag ctcaccaaac
     7081 atgttctacc aaatgcgaaa ttggtgattg atcgattact tggtttttcc acgcctttca
     7141 aggaggcgta acctttattc acgagttggt tgaagctttc cgagacaaaa gacccgactt
     7201 gtttttctcc ttattgacaa agagccatta aaactagaga aaaaattaca actgatcgct
     7261 gattatttgt agaaagaaaa tcaaagtatt acccaataaa cttgagtcat taggcaaaaa
     7321 acactgcgaa actcaagaat gattttcgca gtgtttttgt atatttttta ttaactagta
     7381 ttactacaaa ggtttatttt tcacttctca acgcagcaca aaattgtctt tacttattta
     7441 ctggttgggt tcaaccttct ctactccgat actaatattt gtttgtatac cccttctaaa
     7501 atcggtagtt tccattcaat tgatgggtac tagttgattt taaaaactat gcttattcaa
     7561 ttttttattt tagctcatat atttcgtttc tttctaaatt ttatactgat gaaaacaagt
     7621 agcacaccca atattgacaa tataaactgg ctaatgatgg tttctccagt ttttggaaga
     7681 tgcttatttc cactgcttgt tggattgttt cctcttatat ctgagctatc agcaactttt
     7741 ctattctctt ttgttaaaaa gatcgccact tcttgttctt tttcgatctt gaaagttact
     7801 ggtgtcgcat c
//
LOCUS       DAFLWC010000111         7769 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.115, whole genome shotgun sequence.
ACCESSION   DAFLWC010000111 DAFLWC010000000
VERSION     DAFLWC010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7769
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.115"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..107
                     /locus_tag="L1V17_002606"
     CDS             <1..107
                     /locus_tag="L1V17_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ZinT/AdcA family metal-binding protein"
                     /protein_id="HBN1237314.1"
                     /translation="NESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(176..904)
                     /locus_tag="L1V17_002607"
     CDS             complement(176..904)
                     /locus_tag="L1V17_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1237315.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(917..2197)
                     /locus_tag="L1V17_002608"
     CDS             complement(917..2197)
                     /locus_tag="L1V17_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBN1237316.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(2338..2940)
                     /locus_tag="L1V17_002609"
     CDS             complement(2338..2940)
                     /locus_tag="L1V17_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBN1237317.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            3185..3391
                     /locus_tag="L1V17_002610"
     CDS             3185..3391
                     /locus_tag="L1V17_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237318.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            3703..4422
                     /locus_tag="L1V17_002611"
     CDS             3703..4422
                     /locus_tag="L1V17_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBN1237319.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(4503..5186)
                     /locus_tag="L1V17_002612"
     CDS             complement(4503..5186)
                     /locus_tag="L1V17_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBN1237320.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            5405..7591
                     /locus_tag="L1V17_002613"
     CDS             5405..7591
                     /locus_tag="L1V17_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBN1237321.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
BASE COUNT         2784 a         1309 c         1465 g         2211 t
ORIGIN      
        1 gaaatgaaag tcaagaagta ttgctgaaag aaatggagaa ttggccaaca ttttatccag
       61 atacaatgga tggacgtgaa attgcacagg aaatgctttt gcactgatag gcaaaaaaga
      121 accgaagggt ttggatcggc tggtcattta gtcggtccaa actattcggt tctttttatg
      181 aaatcaattt ctttaatcca cggatagagg ctgggatggt ctcgccgttt gccaacgtga
      241 cttctctggt ttttttatta atcgaccgca cattttgtgt attgataaca taggatttat
      301 gacaacggat aaaattccga tgcattttct cgatttcttt gatcttctca tagaattgta
      361 attgggcatg agtcaaatgg acttccagtt tatgtggcgc tcctagcgaa gtagaaaaat
      421 attggatgtc tttgatcggt aaaaatttga tctcatcatt aaactctatt ttgaagatat
      481 ctttttggat ttgggacatt tgaaaatctt cgaaaatttt gctcaggata tgctcgacat
      541 tttcttttaa atcataaaga tcttctttga cgatataatc agtcggttcg atgttgcttt
      601 ttaagatttt catcgacatt tccgtatggg aagtcacata gattattttt cctaaaggat
      661 ctaattcacg gatcaattta ccgatcgcta caccatccat ttcactgtct tctagttcga
      721 tatctaaaaa gtaaatacca aaagaagaag ttctgatctt ggctgcattg agaagttctt
      781 ccggatcaga ggtagaaata tggacataac tgtctaagtt ttcaatcatg attctatttt
      841 tgatcaccgt tgataaaact tctaattgtt ttggatcgtc ttcacaaata taaatgggaa
      901 tcatatcatt actcctttat tttatttgta tataaatcgt ttgagaaaaa cgctggtttt
      961 caattgatgt ttcaaggaaa agataaggat tggtctttgt caattcatcc aagataaaca
     1021 agccaaggcc ttcgtttttt ggatttgttt ttgttgagaa ccctttttgt ttcaactggt
     1081 ttaacggtaa tgtatttgtt gttgtattga tcacacgaat catcacggaa tgattcttct
     1141 tgagtatggt caattcgatt tttttcttct ttgcagcact agctccttca atcgcattgt
     1201 ccaagataat accaagcata cgtacaaggt ttaccgtatg tttcgtatcc agttcgattg
     1261 gctcaggaaa atgaagctgg acgatcaacc ctttttcctg tgccatcatg agttttaatg
     1321 acagtaaact acggatctca ggaactttca tattatccaa catacttaga ttggccggaa
     1381 aaaggttcat catctggcgt gtaggtaata tcgtttgatc ataataagac cgtaatcctt
     1441 ctaagtcgcc ttctgaaata tagctgtgaa gagaaaaaag cagattttgg taatcatgtt
     1501 tgaattctct caagtcttga tagttttttt ctagatcttt gatataatcc tgttgcatcc
     1561 tgacttgttg ctctaataac tgatcagcta atttcttatt agagattttc caataataaa
     1621 ccaagatgat caggccaaca cacagatata gaatgaaaaa actcgtattc aaagctaaga
     1681 catcaggtgt ttcaccagaa aaacgggtat aaaaaataat gatatagtat gtaaataata
     1741 tcaatgtccc gatcgtaccg atcatacggc ggtccacagt gtgaaaccaa gtctctaacg
     1801 atttttttaa acaaaaagct aataaagcag ataaaaaagc ggataagaca atgtgaaaat
     1861 actgcaatga atctcctggt tcaataaccg aagatttcaa aacaaaaaaa tcgccgatgc
     1921 ttgttaagtg atctcctaaa agcgacgtca ataacccaaa aggaagcgcg taaaccaatt
     1981 gttgacgcga agtcgaaaag aagaaaaaag taagcatcag cattcctata gcaattagag
     2041 cagtaaaaat ccctaaaatc gaatagaccc atccaatcaa aatacaagaa atcagaatga
     2101 ctcccgcaaa cagatatttg tatcggatgt gatggtcaat caataagata caaattgtgt
     2161 aaatcaaata ttgcaacgct atggaccata aaaacataaa gtacagctcc cattgatttt
     2221 taccaaatta tagcacaatt ggcgtattat ttttttaatt tttcagggat tttgaattca
     2281 gaactcatac caaagcagca gccagataca aaaaagtcag ataagttagt taattgttta
     2341 atgattgttt ttttcatgaa agattcctcc aaaattcatc aagtagtttg taataggaag
     2401 caacgtagct atttctaaaa caatcccaag tagcaaatag gtagaaaagt aagaagctga
     2461 gaaaaataac gtaatgagag aaaaaattag aaacatgctg atcgccttct ttaataatgg
     2521 gggacgtttc tcgggttcaa tgggattgat tgctgtacct cttgatccat agcgaagcag
     2581 taacaaaaag cagctgatta acaaaaagac catcattggg aaggagatag tcaattgcag
     2641 atgtttcatc accaagggaa cgccccataa ataaagtagt gtccacagca gacaaacgaa
     2701 ttcagagtcg gaatgcaatc cataagcata tctgcggatg cagatataag aaagaaaggt
     2761 gattcctgtt tccgcccatg agcctgtcac cagagaaaag actagaacga ccgctagttt
     2821 tccaagatta ttcaataaaa cttctaagac aaattttact tggacataca ccatatcttc
     2881 ttccgatttg tctccgctga ataaggcttc taataatttg ttcacaactt tatctttcat
     2941 ctcatacgta cctccaccac aaattttatg ctaaaaaaaa taaaaaacgt cttttgtttc
     3001 ataaaaagtg gttttgacat caaaaccgtc atgatctcct aaaaaaatct tcgttttcca
     3061 agaaccttac caaaaaaagt gacagttttg atacgaaaag tactttttat gacaagtttg
     3121 tgctttttcg agtgatttat gttaaaaaat tactgacctt ataaaaggtg atggagggat
     3181 tcttatggaa aatgaacaat tgtttgaagt cggcgaaaca tatgcattta aatctgattt
     3241 atttgaatca ccaataaaag gaaaaataga aaaaatctat gaaaatagtg tgatgatacg
     3301 tgtcatgaaa tgcgcagtag aagacaatga taccgctcat aatctgcact ggcagttagt
     3361 tgtacgcaaa tcaagtacaa tagaagaata aaaacagata aaatgttgag agcataaaga
     3421 ggttgtgagt ctcccgttta gctctgagtt acaaggaata atgttaaaaa acagcttttc
     3481 atgttttatg aatattgcct tgtgaccgag gtgttggcag gagaatactg tttatttgaa
     3541 aaaagggctg cgacaagact tttgtcacag cctttatttt catgaatagg agttactttt
     3601 ggctactttt agagaagtag cttttaagga gcagataaag tcaaggcttt tatttctata
     3661 aatgaagtag taaaatgaag aacagatttt attacaggaa ggatgccgat aattgtgatc
     3721 attgttgcag gaacgatcgg tgcagggaaa agcacactaa ctgaaatgct tgcccaagat
     3781 ttagaaacaa aaccttttta tgagaacgtg gaagataatg aagtattgcc gctattttat
     3841 tctaatccag aaaagtatac ttttttatta cagattttct ttttgaacaa acgctttttg
     3901 gcaatcaaag atgctttcag ccatgatgac aacgtactag accgctccat ctacgaagat
     3961 agtatgctgt ttcatttgaa tgcagattta gggcgtgttt ctgaagtaga agtaaagcag
     4021 tatgaaggtc ttttagaaac gatgctgaag gagttagaag aaatttcgcc acaaaagaaa
     4081 ccagatctac tggtttatat tcgtgtatcc tttgaaacta tgttagcgag aatcaaaaaa
     4141 agaggccggg aatatgaaca gctagaacaa gatcctgaac tctattccta ctataaagaa
     4201 ctcaatcgac gatacgaaga gtggtatgaa cagtttgata tatgtcccaa aatagtgatc
     4261 gatggggaca aatatgattt cgtagccgat ccggcatgtg gagaacaaat cgtacaagaa
     4321 atcaagatgc gggcaaagaa aatgacagaa gaggcagatg cccagtcgat ccgctacact
     4381 acaaataacc cgaaagcaaa gggaatcttt acaactaaat aatataaaaa ctaagcaaat
     4441 tgctcactcg cagatatttc tctgtgagca gcatcttgct tagttttttt gattcattga
     4501 gatcaaatag tgaaccgatt cgtatgataa aattgccata aatgaaatgt ctgagtgagg
     4561 gccatgatca aaaataaaat ggaaacgatc aaaatcgaat gggcgccaaa cagatgatga
     4621 cagaaaacaa ggacaatagc tcctgcgata aaggcaagaa cgacacttag atagtggaaa
     4681 aatcgatcaa aatctgcttt ttctttagaa atacaataat catataagtt cgttgctacc
     4741 ccttttaaat ttccagttgt aaataaatta gtgtaggcac gcccgttgat tttatcaaaa
     4801 gctacccact ggatcgatgc agtaaaagca atcaaaatcg ttactaatgc gggatgctca
     4861 tggacgggtg tcaaactaac aaagaaaaaa atcactgctt cataatatag aacaaacaag
     4921 cgccagaaat gtttttcttt ttttctaaaa taatcaatta gatactttgt tagaagaatc
     4981 cctaagaaaa agaaaagggt agacaatact tttttaccaa cacttagcca ttctccgtca
     5041 aatgcttgga tgatcgatag aatgatattg ccagtttgag cagaggcaaa agcaccatat
     5101 tggatataag tataactgtc catggctcct ccgataaatg tcagcaaaag tcctattgta
     5161 cgcccctcgt gaaaggaagt ctgcattttt ttcatcacct tttatgaata tttttgtctt
     5221 ccttatctta gcataaacga ttgaaaaaaa aggaaaaatt ttcagaaaac taaaatcata
     5281 tcgcttccca ttttcatttt tagaaaggtc tgttagtata aagaaaaaat agacaacgaa
     5341 actttaaata accaacttga aataaacaaa ttcaaagaag aaagatggga aggaaatcaa
     5401 tcagttgaat gaaaaagaaa ttctccgatt acaaaaagaa ttgaaacgct gggagaacaa
     5461 gtataaaaag cttcaacaag tctttcggct acaagaagaa atcattgcta cctatgaagc
     5521 ggcttatggc gaagcacccg gacttattga ggaagaagta caagtaaaag aaagtgaagg
     5581 aaacagctct ttctttaaaa tgatggagaa acgttcctat aatcgcttca atcaagaaca
     5641 aaaagcagct atcacatatg atatgaagaa acatcttcga atcatagcag gagctgggag
     5701 cggcaaaacg caaacaatct gtgcaaaagc tgtttatctg atgacgcaaa aacaagtaga
     5761 cgaagaacgc atactaatga tcacttttac aaggaacgct gcaaatgaac taaaaaaacg
     5821 agtagataat ttcagccaga gaaaaaccgc tgtccatatc ggaacattcc atagtatctt
     5881 ttttaggata tacaatgaaa tttgtcgaaa atttcctgaa gtagcaatgc aaggaataca
     5941 aggagacttt tcaaaggata ctgcacaaaa agtgaatgct gttttgcaac agctgatacg
     6001 taaatataat ctttatatat ttgatcaata tggagaaaaa acgattgctt ctcggttaga
     6061 ctattggcag aatatgaacc tttcagtaga agaaatggtt cagttagtta aagaaaaata
     6121 tgattccatt gataagaatg cacgacagcc gatatcagaa cgactgtatg gattgctcac
     6181 ggaactccaa gaacaaaaaa gaagccagca attgctagag ttcaatgatg tactccaaaa
     6241 tctgaaaagc gctttggaga atgaggagat ccagcattat atcggccaaa aatatgatta
     6301 tctattcatt gatgaatttc aagatactaa tccacttcaa tgggaaatcg tgaaacggat
     6361 gacaaaggaa aacaggatca agttgattgt tgttggagat gatgatcaga gtatctatgg
     6421 attcagagga tcagagccag catacatcaa gaactttgaa aaagaatatc ctaccaaaac
     6481 tcttttctta ttaactaatt atcgttctcg ggcagctatt gtccaaggag caaatagatt
     6541 gatcagctat aataaaaatg atcggatacc aaaggcgatg attccagcac aaaaagaagc
     6601 aggtgttatg gaagcctatt tgttttctga tactaaagca gaaagtcagt ggctaatcaa
     6661 acaaattcag acatttattc aaaaaaatgg gaaatataag gaatcaatca tattataccg
     6721 atcagcttca caaacgcagc agcttgtcca atctctgctg aaaacgaata ttccttttgt
     6781 actggaagca gatagtccat atgaaggtat ctttggtatc aagtctttcc aacatttcta
     6841 tcaaaaaatt gttcattggc aaacagcact gaatctgcaa aagaaaaatc aggcctacca
     6901 gcaattgctc cggcagctga tggcagactg ctacctgaaa aaaagtgaat gcgatcaata
     6961 cttttctcct aaatatcaaa atatagccgt tgcagattat attttgtcga taagccccaa
     7021 tttaaaatcg aaatctgcag aaatccgaga gtttgaggaa gcgttgcgta aaacagacca
     7081 gcatcaagaa atctattcgc ttgttcaaag ctatcttcat ctgccacgta tagctaagga
     7141 aatcgaccag agtgatcaag aatggatacg agaagaagta aagcagcatg ctactttcag
     7201 aagactccaa gccttatcgc aagaaaccca agcgacagct aaagaattaa aaacccgctt
     7261 gattgcttac agacaaggaa aacttgatgc actatgtatc cagagcattc acaaaagtaa
     7321 aggtcttagt taccgaaatg tctttttgat tggttgtaac gaaggaagtt tgccttataa
     7381 cggagcgaca gaaaagaaag taatcgactt taatgaaata aaagcagaac cagtaacgac
     7441 gatagaagaa gaacgaagac tattttatgt tgcgatgact agagcaagaa atcgtctgta
     7501 tctatgtgta cctcaaatga aaaattcaag aaaattgaaa gtatcgagat ttatcaaaga
     7561 aaccgggagt cgtgtgaaaa aaggaaagtg atagaagaga gggtgtgaca gaagtggtca
     7621 gtttcaagaa agaagaagga atgtacgaaa attgcttctc aaatttttgt gaaatttcag
     7681 cttattttcg aagaagctat ttctggaaca cagtttattc ggaaaaggga ggtgtgacaa
     7741 gaattttgtc acacctccct tatttattt
//
LOCUS       DAFLWC010000112         7601 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.116, whole genome shotgun sequence.
ACCESSION   DAFLWC010000112 DAFLWC010000000
VERSION     DAFLWC010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7601
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.116"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(943..1356)
                     /locus_tag="L1V17_002614"
     CDS             complement(943..1356)
                     /locus_tag="L1V17_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HBN1237322.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1812..2297)
                     /locus_tag="L1V17_002615"
     CDS             complement(1812..2297)
                     /locus_tag="L1V17_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237323.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2436..2651)
                     /locus_tag="L1V17_002616"
     CDS             complement(2436..2651)
                     /locus_tag="L1V17_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBN1237324.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2875..3675
                     /locus_tag="L1V17_002617"
     CDS             2875..3675
                     /locus_tag="L1V17_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1237325.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3694..5562
                     /locus_tag="L1V17_002618"
     CDS             3694..5562
                     /locus_tag="L1V17_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBN1237326.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5555..6046
                     /locus_tag="L1V17_002619"
     CDS             5555..6046
                     /locus_tag="L1V17_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HBN1237327.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6034..6588
                     /gene="srlA"
                     /locus_tag="L1V17_002620"
     CDS             6034..6588
                     /gene="srlA"
                     /locus_tag="L1V17_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBN1237328.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6606..7601
                     /locus_tag="L1V17_002621"
     CDS             6606..7601
                     /locus_tag="L1V17_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBN1237329.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2708 a         1213 c         1443 g         2237 t
ORIGIN      
        1 tttgttacta tgaataacat aataagaaag taaagtggat tgatttgaga tctttttata
       61 cttcaaaaaa gataacaccc aactttcaaa aatatgtttt ggaagttggg acaaacgagt
      121 taatacattt taatacatta ttttttattc aaaaaaaata gcacaatggc aaagatcgta
      181 agagagatca taagccccaa tgaatgacta aaaagaaaag cagaatcaca tgccatatca
      241 tcccatattt cttcaagaaa ataaataagc gggaaaaagg gaaggaatag tagaacatcg
      301 atccagcacc atttttttct tcttttgaaa taacataaaa caataaacat gaacgtgcag
      361 ggaagtaaaa acaaagcttt actcataact aacaaaatac cagctccttt tatttttttc
      421 tcccccacat tcaaagagta acaatggtat gtacttaata atagaaaaat ggatcaactt
      481 gtatgaataa cagctgaaaa gatctgcacc aaataaaaaa cttccagcca aaactgactg
      541 gaagtttatt tttttctgaa atattctaac acaaatatga aaaagatggc cgaagctaat
      601 aagccgattt cgtagcaaaa caatgagata ccagagtcgt aataataaaa tcctctaatc
      661 ttatggataa aatagatcat cggacaagca gataagagta agtatttgtt aggccttttg
      721 aataagtaaa agaaagcact ggtcattatg ataaatggta tccaaaacaa aagtttactt
      781 aagacaatca aatgatcaac tcccatattt tttaccaaga gagatcataa catctttatc
      841 gtaaaaacaa aatatttttt tgctcatttt gaaaatttaa acatactcgt tcttatccaa
      901 atatataaaa atcgcccctc attcatcgag aggcgataag ttctaattta actcaatttt
      961 ttttgtttct tttggctgat aagctgtttt aggtaatacc aatttcagca caccgttttt
     1021 aaaggttcca gtgatttttt cttcatcaac attaggaaga tagaatgaac gtttgtaaga
     1081 gaccgaatgt ctttctttcc gtacatagtt gccatcttct ttatcttctg tatgggactc
     1141 atgattggcg gagatcgtca aagtattatc tgaatattca actgtcgtgt cttctttgtc
     1201 acagccaggc atatcagcag ttagtttgta ttctttttca ttttcgacta aatctacttt
     1261 tggataactt gaaacaccta aaaaatcatt gaatgctgga ctaaacacgt cattgaaatc
     1321 agggaacatg tcgcgaatgc taggtacatt tgccattttt gatcatcctt tcaataagta
     1381 ttttttattt atccctattt acgtaataac tctattttga aaaaaatgca agtataatgg
     1441 ttagctttgt gaatatttca tctaatacga tacaaaggct atctttctaa tttgaaaaag
     1501 ggatcattaa aataataaga agaaaatatg tcaaaaggta aaaaagtaaa ttcttctatc
     1561 caaatataga aaaattgaat ctagaaaacc gcccgacaat aaatttcatt aactcagttg
     1621 accgaaaatg aagtagatac caaaaattta tcaagagagc aagtagagaa gtgagtatat
     1681 tcataagaga aatagctgta acgaattatt aggttaatgc aaatgcttat ttatactccg
     1741 tataactttc tcagaaaaaa tgataccaat aatgacttgc tagtactgta aatccgtata
     1801 atatcatcta atcaaaatgg tgttccattt gcatctgtca tcgtaatcga tccttcgggt
     1861 gacactcgat aaaaaccaac gcttccagat cctccttggg aacggatttg tttgctggaa
     1921 gctgtgaaca aataatctcg atcaattttt tgataaaagc taataacaat atcgtcactt
     1981 tgtaattcgg aacggtgggc aataagaaat agaagtgctt tgtcagagtt ttctaatgga
     2041 agagaaggta cagtgctttc ttgcatttca gatgttgaag aaatgctaaa cgactgaata
     2101 cttgattggc tatgttgcga atctacatta ccagtagaag tattagtaat ggaagtagta
     2161 gaagtacttt tagttgaacc aacctcagtt gttgaaatgg ctgctgaaga ttctttaaca
     2221 gaattctttg ttttatatcc acaggcagaa aaaagtatta cagttcccaa caagcctgcg
     2281 taaatccctt tatgcatgat agctcctcct aaaatagatt atctttattc agtatatcac
     2341 ttaaacaaag aaaagcagat ggtttaaaat gaaaaaacct tcccaataaa gggaaggttc
     2401 atgaagataa taactttttt aataattata gctttctaat atctttcatc aacttttcta
     2461 gtaatcattg ggaaaaattt caagcagtag atcgcacaaa tacctacgac gatataaatg
     2521 atcttcgcaa aaatagttgt tgaaccacca gcaatcatag ctactaaatc aagttcgaac
     2581 aagcctacca acagccagtt caaccctccc acaatcaata aagttaatgc aatagcatct
     2641 aaagttttca ttagaattct cctttcttaa atgataaaac aattatatat caaaaagaga
     2701 aacattgctt atataacgct caggaatttt agcaatctat gcaaaaagat gaaaattttt
     2761 tttgctcttc cattagtaca cattttttag ctgaagctgt aaatttcatg tcttaatttt
     2821 ttttagtgag cttttatact ggatttgtaa gaaaaaagaa ggagaggatc acatatgtcg
     2881 gattggttgg atattgcagg aaaagtagta attgtaactg gaggttcctc aggaattgga
     2941 agaagtatcg tcgaaaattt gttgaagcag aatgcacaag tagcgaattt tgatgtaact
     3001 gaatgccgta tacagcatga aaacctacta tctttaaaag tcgatgtgtc ttctaaaacg
     3061 gacatagaag aagggatata taaagtaatg aaacatttca agacgatcga tggtctagtc
     3121 aataatgcag gaataaatat tccttctctt ctaatagata gaaatcatcc aaaaagcaag
     3181 tatgaattat cagaacaagt ttttgataag atgatcgctg tcaatcaaaa aagtgtatat
     3241 ttgatgagcc aagcagttgg aagaatcttg gtgcaaaagg gatcaggagt gatcgtgaat
     3301 ctttcttctg aatcaggatt ggaaggatca gaaggacaga gctgttatgc tgctacaaaa
     3361 gcagcgatga acagttttac tcgttcttgg gcaaaagagt taggaaagag gaatgttcgt
     3421 gtggtaggtg ttgcaccagg gatactggaa gaaaccggtt tgagaacaca agaatatgaa
     3481 gaagctcttt cttatacgag aggtataagc gtcgaacagc tgagaaacgg ttacagtcga
     3541 acaagtacga tccctctagg aaggagtggt aagctgcaag aagtggcgga tctagtctgc
     3601 tattatcttt cagaaagatc aagttatatc actggagtca cgactaatat ttcaggaggt
     3661 aaaacaagag gataaaggat aggggggacg cacgtgacgc tagtaaacag atggtaccaa
     3721 ttattgaaat tactagtcac tcacaagaaa gtttcaatcc aggaagtgca aaaagaaatc
     3781 aaaaccagta atcaaaccat aaaaaaagat attggggagt tgaatgaaga aattgccggt
     3841 attgcaaaaa tcatccaaaa aaacaaacat tttgaacttg aaatttatga ttttgatttt
     3901 tttgatgaga tcatgcaagg aaaattgaaa acagccagtg atttcaattc ggcatccaaa
     3961 agaatcgctt atttactaaa taggctgatc gaaacagagg atttcttacg tatggatgat
     4021 ttgtctgaag aagtcggtgt cagcagagga acagtggtca aggatctaaa gacattaaaa
     4081 gagatgatca atgattttga tgtaaagatt acaggcacac caaataaagg actaagaata
     4141 ataggagatg agctagaatt acgactactt ttattttatt ttgtttctcc ctacttttca
     4201 gagacgaaaa cagaacagtt tctagaagaa aaacaagcaa tcaaacattt tcagaagaag
     4261 acgaatgcta gtaaacaaga aatcaccctt ttaacgaaag ttatcggtat ttctttgaat
     4321 agaatctcta gtaactatct gttgaagaag cccatcaatc gttacagtgg gtgttttgaa
     4381 tatatccaag aattcaatga actgatcaat cagttggaag aaatctatga actaactttg
     4441 agccaatatg aaaaagattt tatcagtttt cctttgaaca tcatcaacac aagtataacg
     4501 atgataagga aagctaactc tgatttgcgc ttatatttcg accccatgat gatgcgtatt
     4561 cgacgattag atctcattga tctggatgag tccttcttat atcaagagat gaaacagcac
     4621 ctctctttat tgataaatcg ggtaattttt cgttatcgat tgactgattt attttatggt
     4681 gagatagaaa aaaagtatcc tttttcttac caaatcgcta gcgaatgcat acaagcatta
     4741 gaagctatct tgcaacataa gatctctaaa gtagagatca gctacctaac gttgtatttg
     4801 gagttagcat ttcgatatca aaaagagcat ttttcctcta aaaaagtagc cattgttcat
     4861 acgacaggaa aaggaacagc attaatgatc caaagacaaa tcaaaaggat attggggagg
     4921 gatatacaaa taacacatgt ttcagaagaa caatatgaaa aagtagatct aaacaaatat
     4981 ttcgctgttt ttacaacgat tccgttaaaa aatgtaaatg aagagacacc ggtgatccat
     5041 ttgactaatc tttttgatga ctcttggtta agggcacaat ggcaaaaagc aaaaaaaaag
     5101 cgattagccg ggtttcattc tactgttttt ttctatcaaa tatggaaaga aaaaaagacg
     5161 tatcaagaat atttaaacaa attagtcgct cctttgatca gaggctatta tgtggatgaa
     5221 gaatttgaaa aaaggatctt gaaaagagaa tatcagcaaa gcacatttgt taacaaagaa
     5281 tttgcttttc ctcacacaac caaccagcta tctcaacaca ttgttttatc agtagggcta
     5341 ataactgatc aaggtttagc agaaacagga ggaaatggag ttattttttt atttgccata
     5401 cctgaagaaa tgacggctga agttgagaat gaattatttg agctatacga tatcctattt
     5461 gaactcataa aaatgggaat agatgagttt attgaattag caccgacaca agaatcattt
     5521 ttaaaactaa tcaaaagtaa aggagagaga cttcatgaat gatatgtatc tattcatagt
     5581 tttcgcagct tcagcttatg tgctgcaagc agttatcagt tggaagcaac taaagcattt
     5641 caatcaaaca tatagcgaac tgcgaagaaa aggaaaagta gcgattggta aacgacctgg
     5701 gaaaatccgt tcaggcacga ttgttatgct agctatagac gatcatgatc aagttttaga
     5761 agtcagaaaa atgcaagggg ttacatcttt ggcaaaattt cattcattac ctgtctatgc
     5821 gggtgaagat atccattaca tcgatcgtta ccatccctca gttcgagcgg aagatcgttt
     5881 gacacaagca gctttagaaa atgccagaga agtatactta cgaatagagg caggaaatga
     5941 aaaaagtgaa caaccttcat tgccttttat tgctatgctc aataattttc ggatatggaa
     6001 aagtacgatc aaagaaaaaa ggagtgacaa acgatggata tcataacaaa atttgctgag
     6061 ggatttatga ggctgttcca aacaggtgca gaaacattca taagctggat gacaggaatc
     6121 gtaccagttg tcttgatgct gatggttgca atgaatacgc tgattgcttt tttaggtgaa
     6181 gaccgagtaa cgaaagtagc caaattatca gcgaaaaatc cgcttactcg ttaccttgtg
     6241 ttaccgttct tatctgcttt tatgttggga aatcctatgt catttacaat ggctcgtttc
     6301 cttccagaat actacaaacc aagctattat gctgctcaag ctcaattttg tcatacgagc
     6361 aatggtgtat tcccccatat taatcctgga gaattgtttg tatggatggg gattgctcaa
     6421 gggatcgaaa ccttagggct aaattcgatg gagctggcta tccgatactt gcttgtggga
     6481 ctgctgatga actttattgg tggttggata actgatttta ctactggatt tgtatgcaga
     6541 cagcaaggaa tcgttcttag caaaaaagta gagctttcag ttgattagag aaaggagagt
     6601 tttaaatgta tggtgatatt aagatcgtaa gaggaaacgg cgggtatgga ggtcctttga
     6661 ttattaggcc gacaaaagat aaacacaagt tcatctatgt cacaggtgga ggtgagaggc
     6721 caatgatcgt agataaaata gaagaactga caggtatgga gtctatcaat gggttcaaaa
     6781 catcaatacc tgatagtgaa atcgcgcttg caatcgttga ctgtggaggg actcttagat
     6841 gtggaattta tcctaaaaaa gggataccaa ccatcaatat cgtttccaca ggaaaaagtg
     6901 gcccattagc acaatatatc actgaagata tttatgtttc agcagtaggg ttagaacaaa
     6961 tacagccact aatggaaact gatgataaca aagaaacagt aaatactgca tctccagata
     7021 aaaagtacaa atatgatact tctaaaaaga taaccgagca aaaagcagag cagcaaaact
     7081 ggatagcaaa aattggaatg ggcgcgggaa aagtagttgc tacattcaat caatcagcaa
     7141 gagaagcagt agatacgatg atccggacag tgatcccttt tatggctttc gtttcccttt
     7201 tgattggtgt gatacaaggt tctgggatcg gtaatgtatt tgctaacatt atggcacctt
     7261 tagcaggaaa tgcagttgga ttaacaatca ttggctttat ttgttcactg ccatttttat
     7321 ctcctttgct tggtccaggg gcagttatta gccaagtgat tggaacattg atcggtgtag
     7381 agattgggaa aggaaatatt cctccccaat tagcattacc ggcactattt gctatcaata
     7441 ctcaaaatgc atgtgatttt attccagtcg gtctaggttt ggaagaagca aaagctgaga
     7501 cagtagaagt aggtgtacca tcagttcttt attcaagatt tcttaacggc atcccacgag
     7561 ttatcattgc ttgggtagca agttttggat tatatagctg a
//
LOCUS       DAFLWC010000113         7410 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.117, whole genome shotgun sequence.
ACCESSION   DAFLWC010000113 DAFLWC010000000
VERSION     DAFLWC010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7410
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.117"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(15..344)
                     /locus_tag="L1V17_002622"
     CDS             complement(15..344)
                     /locus_tag="L1V17_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBN1237330.1"
                     /translation="MNTNDIATVYVAFTAAEGGKRRPVYILKNGLDTISFLSITSKYH
                     TKSDKIKLKYVEIRDWKQAGLKKESWIDVGTLNELPKNNKKVKWKKIGELSPSDLQRL
                     EERMEEL"
     gene            complement(334..606)
                     /locus_tag="L1V17_002623"
     CDS             complement(334..606)
                     /locus_tag="L1V17_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HBN1237331.1"
                     /translation="MEKMAKLQISMDEKLKNEAESIIDELGMSPKTAVTVFYKQIVEQ
                     GKIPFSIELSEKSKRIHNIQRLAEKLPVQKLDTDEKIEEWFNEDEY"
     gene            complement(1057..1860)
                     /locus_tag="L1V17_002624"
     CDS             complement(1057..1860)
                     /locus_tag="L1V17_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBN1237332.1"
                     /translation="MRFLHLSDIHFRENYQTNLFTAELFPTIKNPQLALEKLLQELSL
                     TVYDFILLTGDLVHEGGISDYQVLRKMLDQYFPTTPYYFCRGNHDRRSVFFEGMSVES
                     NETGEYIHCTNQNGLRIISLDSAQDTQHEGKISIGQMIQLQEWLGTPAEKGTILLVHH
                     PLSWEDPSIVTEVPEGFAELIAESDILGIFVGHIHQGSSAEFAGKKQFMAESLSFGVD
                     EYPDYSLFTNRTGFTSGSLIDGKIFTYQHYLTPHQIEIGRMKKPITGNH"
     gene            complement(1838..2962)
                     /locus_tag="L1V17_002625"
     CDS             complement(1838..2962)
                     /locus_tag="L1V17_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1237333.1"
                     /translation="MGETLELRNIGKKYGEHTILKEIDLAVAAGERIVLLGPSGSGKS
                     TLLRMIAGLEKITSGELFLGTQLANKLPCGEREIAMVFQNYALYPHMTVKENIIFALR
                     ANKIKTADIQHRLEEALKMLGLTPYQDRLPKDLSGGQRQRVALARAVVKRSNYFLLDE
                     PLSNLDVRLRLDARKELVKIHQRYKQTFVYVTHDQIEAMTLADRIVLLNEGRIQMIDT
                     PKNVYTKPKNTFTANFIGSPGMNIMPVTYDQGTLKVASQFLTLNPAWQKQLLQVSGSL
                     YLGIRPEHVTFSKETSDLHGQVKYRELLGQSYAYTVKVDGIEMIVLNEKPTWQIGDAV
                     NLRIEPERMHFFDYQTQENLGYPDYFIEERGNSHALFASL"
     gene            complement(2978..3793)
                     /locus_tag="L1V17_002626"
     CDS             complement(2978..3793)
                     /locus_tag="L1V17_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBN1237334.1"
                     /translation="MKIKRWLPHLLFMFIIIIIIYPLLFIMANSFKPLKDAYQTITSL
                     IPQPFTLENFCYLFENLPIIKITRNTFFIATIITVVKLGVAFFAAYSFTYCRIKGKKI
                     WYFIIIGTMFIPFTVAMIPNYLLIAKLNLIDTTWGVIIPQFADAMGIFLLTQTMREIP
                     VSLLDVAALDNIKQTTVMSKIVFPLTRHAITSTGIWFFITSWNEYVWPVLILRTVDNY
                     TLPLAMQTYISSEGGTNFTVAMAISLITMFVPLVLYAIFQKYIIGTFVSAGIK"
     gene            complement(3783..4655)
                     /locus_tag="L1V17_002627"
     CDS             complement(3783..4655)
                     /locus_tag="L1V17_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBN1237335.1"
                     /translation="MKRYVGYLYLAPAIILLGVFVFYPLIYTIYLSFFDWNMVAPTKE
                     FVGFANYVKVLTDPVFHKVLKNTLSYTVLFVLLSCVFPYITSFLLGIVIEKGQNLYKP
                     LFFIPAVISLVVAGMVFTWILNPVSGPIAVLLGNFGLRLPMWMNLQGWVIAVIAGITA
                     WKVFGYNFIVIFAAIVGIDQEMIEAAKLDRVPIWRIFFTIVLPMSSSTGLYLLVMTIV
                     QGLQYVFTPIKIITRGGPNNGSANVIYYAYQKAFEMYKVGESSAISVLTLLIFAVFLG
                     VIFKFVEKGVYYEN"
     gene            complement(4740..6029)
                     /locus_tag="L1V17_002628"
     CDS             complement(4740..6029)
                     /locus_tag="L1V17_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBN1237336.1"
                     /translation="MLKKNLVIGVVSVLSVISLAACGSGNTKTTKKSEGRVTIEYWHV
                     NADTLGGKTVNELVDKYNQSQDKVKVVAKYNPDMYKGLMQNLQASVASKEIPDVVQVG
                     WAFKDYFAENFKYTNPQSLVEEVDPDNADYFKDHFLDNIMALSEKDGKQVGIPYSISN
                     PVLYLNQDILKAAGLDENGPKTWEEVQTFSKIIKEKTGKYGVYIQEPADNWAQQAILE
                     SNGASVIKDGKATFASKDGIAAYELYQRMVKDQTALHTTWEQGVQSFIDGNVAMVYTT
                     IAQRDNIQKNSTFTAKAVESPSWEGKKVKLPAGGAMLAVTSQTDKKKEATWDFLKYLY
                     SVESLAKWTEGTGYLPPRKDVADAQNGLKAFLAENQMMIPAIDQMDKMVSWSSFPGDA
                     GLEAEQKLLDMRDKILSGNSVNETMKATQKEINELLK"
     gene            complement(6257..6901)
                     /locus_tag="L1V17_002629"
                     /pseudo
     CDS             complement(6257..6901)
                     /locus_tag="L1V17_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
BASE COUNT         2278 a         1590 c         1136 g         2406 t
ORIGIN      
        1 tctttttagt attattataa ttcttccatg cgttcttcca gtcgctgtaa atcgcttgga
       61 cttaattccc caattttttt ccatttgacc tttttgttgt ttttgggtaa ttcgtttaga
      121 gttcctacgt caatccaaga ttcttttttt agtcctgcct gtttccaatc ccttatttca
      181 acgtatttca gctttatttt atcggattta gtatgatatt ttgaagtaat tgacagaaac
      241 gaaattgtgt ccagtccatt ttttagaata tagacaggcc ggcgtttacc gccctctgca
      301 gctgtgaaag caacgtagac ggttgctata tcattagtat tcatcttcat tgaaccattc
      361 ttcaattttt tcgtcagtgt ctagtttttg gacaggcaat ttttccgcta atctttgaat
      421 attatggatt cgtttacttt tttccgacaa ttcaatagaa aatgggattt ttccttgctc
      481 aacaatttgc ttataaaaaa cggtgacggc tgttttgggg ctcatgccta gttcatcaat
      541 aatgctttct gcttcatttt tcaatttttc gtccatagaa atttgtaact tagccatttt
      601 ctccacctct ttctgacaaa cacattatat cacggaaaga gttcaaatgg aattaataca
      661 actacttttg aactccttga aatgcagtgt atttatctaa atataaggaa aggatatagt
      721 gctaaatggc cttgatagat agaaaagttt caaaatccgc cacagcgata attgaagcga
      781 acactcaacg acacacagaa caggaaaaga ctcctaaaag aaccaaatta actaggacgt
      841 gtctgaaaac tccacaaaga tgtggtatgc tctggtaaaa aacgaatggc acaaccacga
      901 agaccgatat ggttcttgga aaactttctc cacccttttt gtaattggag ggatagtggt
      961 ttattgatag cgattttcca agttcttcaa gtggaaccag acattgagca ccacggctaa
     1021 aaagtgaatg aagtctttat ttttaatcaa taatttttaa tgattaccag taattggttt
     1081 tttcatgcgc cctatttcta tttgatgtgg agttaaataa tgctgataag taaaaatttt
     1141 tccgtcaatt aaactgccac tagtgaatcc tgttctattg gtaaaaagag aatagtctgg
     1201 gtattcatct acaccaaatg ataaagattc agccataaac tgttttttac cagcaaattc
     1261 agcactgcta ccttgatgga tatgtcctac aaaaatacct aaaatatcac tttcggcaat
     1321 caattcagca aaaccttccg gaacttcagt tacaatagat ggatcttccc acgacaatgg
     1381 atgatgaacc aataaaatcg ttcccttttc agcaggtgta cccaaccact cttgtaattg
     1441 aatcatctgt cctatcgata tttttccttc gtgctgggta tcttgagcag aatccaagga
     1501 aataattcgt aacccatttt gattcgtaca atggatatac tctcccgttt cattgctttc
     1561 aacactcatt ccttcaaaga aaacactgcg acgatcatga ttcccacgac aaaaatagta
     1621 aggtgtggtt gggaaatatt gatccaacat tttccgtaag acttgataat cagaaatccc
     1681 cccttcatgt actaaatcac ctgttaatag aataaaatcg tacactgtta acgagagttc
     1741 ttgtaacaat ttttccaatg ccaactgtgg atttttaatt gttggaaata gttcagcagt
     1801 aaacaagtta gtttgatagt tttctctaaa atggatatca gagagatgca aaaagcgcat
     1861 ggctattccc tctttcttca ataaaataat caggatatcc taaattttct tgcgtctgat
     1921 aatcaaaaaa atgcattctt tcaggttcta tgcggagatt gactgcatca ccaatctgcc
     1981 aagtaggttt ttcattaagg acaatcattt ctataccatc gactttaacg gtgtacgcat
     2041 aactttgacc taatagctca cgatacttca cttgaccgtg taaatcgctt gtttcttttg
     2101 aaaaggttac gtgttctggt cttatgccta aatacaatga gccactaacc tgaagaagtt
     2161 gtttttgcca agctggattc aatgttaaaa attgactggc tacctttaat gttccttgat
     2221 cataagtaac tggcataata ttcatgcctg gcgaaccaat aaaatttgca gtaaaagtat
     2281 ttttaggttt cgtataaaca tttttcggcg tatcaatcat ctgaattcta ccttcattca
     2341 ataaaacaat ccggtcagct aacgtcatcg cttcaatttg atcatgagtg acgtagacaa
     2401 aagtttgttt ataacgttga tgaattttta ccaattcttt tcgtgcatcc aatcgtaaac
     2461 gcacatccaa atttgataac ggttcatcta ataaaaaata attactccgt ttaaccaccg
     2521 cacgagccaa tgctacacgc tgccgttgcc ctcctgacaa atctttagga agtcgatctt
     2581 ggtatggcgt taaacctaac atcttcaaag cttcttccaa acggtgctga atgtcagctg
     2641 tcttaatttt attcgccctt aatgcaaaaa taatattctc ctttacagtc atgtgaggat
     2701 ataaagcata attttgaaaa accattgcga tctctcgttc tccacaaggt agcttatttg
     2761 ctagttgtgt acctaaaaaa agctctccac tcgtaatttt ttccaaacca gcaatcattc
     2821 tcagcaaagt agattttcct gaaccagatg gtcccagtaa cacaattcgt tctccagcgg
     2881 ccacagctaa atcaatttct tttaaaatgg tatgttctcc atattttttt ccgatatttc
     2941 ttaattcaag cgtttctccc atgatttgtc ctccaattta tttaatacct gcagaaacaa
     3001 aagtcccgat aatatatttt tgaaaaattg catacaagac taacggtaca aacattgtaa
     3061 ttaaactaat cgccattgct acggtaaaat ttgtcccacc ttcagaacta atataggtct
     3121 gcatcgccaa cggcaaagta taattatcta ctgtccgtaa aattaatacc ggccaaacat
     3181 actcattcca agaggtaata aaaaaccaaa taccggtaga agtaatcgca tgtctagtaa
     3241 gaggaaaaac aattttactc atgacggttg tttgtttgat gttatccaat gccgccacat
     3301 ctagaaggct cactggaatt tcccgcattg tttgcgtcaa taaaaaaatg cccatcgcat
     3361 cagcaaattg tggtattatc acaccccaag tagtatcaat taaattaagt tttgcaatca
     3421 acaaataatt aggaatcatc gcaacagtaa aaggaatgaa catcgtacca atgatgataa
     3481 agtaccagat tttcttccct ttgattcggc aataagtaaa actatatgcc gcaaaaaaag
     3541 ctacgcctaa cttaacaacc gttataattg tagcaataaa aaaagtattt ctcgtaattt
     3601 tgataattgg aagattttcg aacaaatagc aaaaattttc caaggtaaac ggctgtggta
     3661 tcaaactagt aatcgtctga taggcatctt tcaatggctt aaaagaattg gccataataa
     3721 acaataatgg atagataata atgattatga tgaacataaa taagagatgt ggcaaccagc
     3781 gtttaatttt catagtaaac ccccttttcc acaaatttaa atattacccc taagaaaaca
     3841 gcaaatatta ataaagttaa aactgaaatt gctgaagatt ctccgacttt atacatttca
     3901 aaagcctttt gataagcata atagatcacg tttgcactac cattattcgg tccaccacga
     3961 gtgatgatct taatcggagt aaacacatac tgcagacctt gaacaatggt catcaccaat
     4021 aaatatagtc ctgtcgaact actcataggc aacacaattg taaaaaaaat gcgccagatg
     4081 ggtacacgat ccaacttagc tgcttcgatc atctcttgat caattcccac aattgctgca
     4141 aaaatgacaa tgaaattata accaaaaact ttccaagcag taatacctgc aatcacagca
     4201 attacccaac cttgtaaatt catccacata ggcagtctta aaccaaaatt tcccaacaag
     4261 acagcaattg gtcccgatac cggatttaat atccatgtaa aaaccatccc cgccactacc
     4321 aaagaaatca cagctggaat aaaaaataat ggtttataca aattctgccc tttttctata
     4381 actattccta ataaaaagga tgtaatatat gggaacacac agctcagcaa gacaaataga
     4441 acggtatagg acaaagtatt cttcaacact ttatgaaaga ctggatcagt cagcaccttt
     4501 acatagttgg caaagccaac aaattcttta gtgggggcca ccatattcca gtcaaaaaaa
     4561 ctcaaataga tcgtataaat caatggataa aaaacaaaca cgcccaacaa aataattgct
     4621 ggcgccagat acaaataacc tacatagcgc ttcatttccg acagcctcct catccttatg
     4681 tcaaaagcag acgaccttgt ttttcctttc ttacaggcgc tgtcgtctgc ttgctttgct
     4741 tatttgagta actcattaat ttccttttga gtagctttca tcgtttcatt gacggaatta
     4801 cctgataaaa ttttatcccg catatccaac aatttttgtt cagcttctaa tccagcatct
     4861 ccaggaaatg aactccaact gaccatctta tccatctgat caattgctgg tatcatcatc
     4921 tgattttcag ctaagaaagc ttttaatcca ttttgggcgt ctgcaacatc tttacgtggt
     4981 ggtaaataac cagtaccttc tgtccattta gctaaagatt caacactata aagatatttt
     5041 aagaaatccc aagttgcttc ctttttctta tccgtttgtg atgtaacagc taacattgcg
     5101 ccaccagcag gtagtttaac ttttttccct tcccaacttg gtgactcaac tgctttagca
     5161 gtaaaagtac tatttttttg aatgttgtcc ctttgagcaa tagtggtata gaccatcgcg
     5221 acgttaccat caataaagct ttgcacacct tgttcccacg tagtgtgtaa tgccgtctgg
     5281 tcttttacca tcctttgata taattcataa gcagcgatac catctttaga agcaaaggta
     5341 gctttgccat cttttattac acttgcccca ttactttcta aaattgcttg ttgtgcccaa
     5401 ttatcagcag gttcttgaat atacacgcca tactttccag ttttttcttt tattatctta
     5461 gaaaaagttt gaacttcttc ccaagttttt ggaccatttt catccaagcc cgctgctttt
     5521 aatatatctt gatttaaata taaaaccgga ttactaatgg agtaaggaat acccacttgt
     5581 ttaccatctt tttcagacag tgccatgata ttgtctaaaa aatgatcttt aaaataatca
     5641 gcattatccg gatccacttc ttctactaaa gattgaggat tagtatattt gaaattttct
     5701 gcaaaataat ctttaaaagc ccatcccact tgtactacgt ccggtatttc tttggaggca
     5761 acagaagctt gtaaattttg catcaagcct ttatacatat caggattata ttttgctaca
     5821 accttcactt tgtcttgaga ttgattgtat ttatctacta attcattcac tgtttttcca
     5881 cctagggtat ccgcattaac atgccaatac tctatcgtta cacgaccctc cgattttttt
     5941 gttgtcttgg tattcccact accacaagct gccaaagaga tgacacttaa aacagacaca
     6001 acccctataa caagattttt ctttaacata acattaactt cctcctaatt tctttatggc
     6061 catttttcta atcaagaaat attatgaact accaatgtaa atttctagtt aattttctgt
     6121 aaataattcg aaatttgtgc atttcggggt acagggtcac tggacatatc catcaagcta
     6181 agaataaagc ccccatatgg tcatgtatcc catctccaaa tctcttaact cctctgtttt
     6241 gattataaaa tagtttattc tgtgctcctt tcttccataa ataggcccat gcacaacgtg
     6301 aggttatatt ataaacacca cagcgcgcaa ggtactcaat cgtttctagt tcattgactg
     6361 tccatacaga aaatgtcaat cctagctgct gccccacttc acgggccaac ttagttaacc
     6421 atccttcatg aatattgacg atttgaacgc tttgataggc taatttctgt aaggtatcga
     6481 tcaaatctgc ttcggtaata tccccaagtt ttttcccttc gaactgattt tcaatattat
     6541 aaaatatatg ctttccccaa atcgcagccc aagataattg tacatagcca ctaagaacaa
     6601 tttgtggcca gatttgatag gtttgtgcca gcgaaaaaac ggccatttcc aatccctctt
     6661 cttttaaatc acagttaatg gtcatggttg ccttctcatt ggccactgct tgaaacacct
     6721 gctcaagggt taccgaatct gggacaactt cttacctgtc atgggctagt attagcgtac
     6781 catctgtttg ctgacgcaca tctacttcaa aacaaagctg gcgatccaaa caaaagcgaa
     6841 gaaatgccca gctattctcc tccgtattgt cactaccaga gtgtgcagtg atcatggtca
     6901 ttttgacccc tcctttaatt ccgtgatttt ctcccacacg tccactatac cgatgaagcg
     6961 ttaatttctt gttaatttct tgtaaattcc ctgcgttttt tcagtaaact agttgtaaat
     7021 cttgcatgct ccttcctacg aactcatgaa tcgtcgattt tgcccttcta gctagtttca
     7081 ccaattaagt agttctacat tccccgcttt taacctacta cacctttttt tgttttcagc
     7141 tattccttct tcttgctgaa agtccttgag gttctttctt acaggatacc atcaaggtgt
     7201 tcaatggctt attcccattg aatgaccgag acttactatc agatttctgc tcgttgaacc
     7261 aagtctttga tacaggattt cttccgtcat cttctcacaa ataccacctt gcgtttctct
     7321 agcgattggt cgatgtgcac cctcccagtg gactgtcact accccttttt gctatgccta
     7381 gcccacaaaa aaagctgtcc tcacagacag
//
LOCUS       DAFLWC010000114         7302 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.118, whole genome shotgun sequence.
ACCESSION   DAFLWC010000114 DAFLWC010000000
VERSION     DAFLWC010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7302
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.118"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(204..1652)
                     /gene="cls"
                     /locus_tag="L1V17_002630"
     CDS             complement(204..1652)
                     /gene="cls"
                     /locus_tag="L1V17_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBN1237337.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGEIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHTTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            complement(1804..2697)
                     /locus_tag="L1V17_002631"
     CDS             complement(1804..2697)
                     /locus_tag="L1V17_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1237338.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            complement(2681..3367)
                     /gene="ftsE"
                     /locus_tag="L1V17_002632"
     CDS             complement(2681..3367)
                     /gene="ftsE"
                     /locus_tag="L1V17_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HBN1237339.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            complement(3472..4573)
                     /gene="prfB"
                     /locus_tag="L1V17_002633"
     CDS             complement(join(3472..4500,4502..4573))
                     /gene="prfB"
                     /locus_tag="L1V17_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBN1237340.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            complement(4699..7233)
                     /gene="secA"
                     /locus_tag="L1V17_002634"
     CDS             complement(4699..7233)
                     /gene="secA"
                     /locus_tag="L1V17_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBN1237341.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
BASE COUNT         1939 a         1630 c         1277 g         2456 t
ORIGIN      
        1 gctatactgg ctttgaaatg tgtctctttt aatagcatat attagcttat ttcttgcttt
       61 ccccaaaaaa caagagatac cccaaagtta atttcgctca tgcgagacgc tttctccatt
      121 tctgacgtac tctcagaaat ggccccgtta aaaaaggaca cgagatctcc atctgttgat
      181 ggttctcatg tcctttttat gttttaaagg agcggcgaaa tcaatcttgc taatccttct
      241 ttcatcttga tgattattcc tcggttttca tacatttctt ttgtgagatg cgtagaaatt
      301 ttcgagtctt caaaaaaagc ttttcttaca cgtgaagcca ttcgttcatc ataaaccagt
      361 gtattgacct caaagtccaa gcgaaatgaa cgaacatcga tatttgctga gccaactgaa
      421 acaatgccac catcgataat catcgtcttt gcatgaataa atccattctc atatgtttcg
      481 atccttgctc catactcgat cagctctgca gcgaaagaat acgttgccca gtaaacgaga
      541 agatgatctg gtttgttagg tatttggata tgaactttta cgcctgaaag aagagccaac
      601 ttcagtgctt catgaatcga tccatccggt atgtaataag gcgtttggat caatatctcc
      661 cgtttggcta acgaaatcat tttcaaataa gtcattttga tttgttcatg ttcggtatct
      721 ggtccgcttg tcacgatttg aacagctata tcaccagtag tgtgaatgga cggaaaaaat
      781 ttgggagaat agcctacttc ttttgtatgc tgagaattcc agtccatcaa aaaacggttt
      841 tgcaaggtat acaccgcttc tccgtaaata cgcaaatgat tgtctcgcca ataaccaaat
      901 ttctttacca atcctagata ttcatttcca acattgaacc cacctgtata tccgatttcc
      961 ccatcaataa ctacgatttt acgatgattg cgataattga tccgaggatt aatatacgga
     1021 acaaatagag gaaagaaaaa tgcgacttct ccgcctgctt ttttcaaatt ctgaaaaaag
     1081 ctggaagaaa cttgtgtgga accccatgca tcaagaagga ctctgacttt tacccctcgt
     1141 cttgccgcct ctgtcaatgc atctcgaact tcttcaccta atgcatcact gcgataaata
     1201 taatactgga agtggatatg gtcttctgcc tgcttgatat cttcaatcag cgcatcgaat
     1261 ttttcacgac catctgtaaa taaagtgatt tcatttttag tcgtatagag cgtactttca
     1321 aataccgtga gcatatagat caattgtttc acatctactt gtccagtagg cggatgagga
     1381 taaagccctc gcatcaatgc ctgtttgtct tcttcaattt ccaggttctt accgattttc
     1441 ccttggatct tcaaatcaaa gattttctct ttggaaatcc ctcttcctaa aaaaatatat
     1501 aaaataaatc ctacaactgg aatgaacatc aaaacgagca gccatgccca tgtttgagca
     1561 gtttcctttc tttctcgaaa aacgatgata aaggaaagca aaatattcat aatcaaaagg
     1621 atcgtaaaaa aattgtcaac gataattttc acggcttcac ctcttcttct accaacttaa
     1681 gaatacccaa gttgtttttt aaagtaaagg gaaaaaagcc gcttccttct attctcctag
     1741 ccaataaaaa aagaaagctg gaacgaaact gtccaacttt ctcattttat ttatattgtg
     1801 gtattagaat ttcaagaaac gtctcataga aatgatcgag ccaagtgaac caatgatcac
     1861 accaatgccg accattaaaa gattgatttt ccaaacgata ttttgtggat gaatcaatga
     1921 ataatgggaa cgtaataatg atggattgat caattggaaa aaccatgcat aaccaaatgt
     1981 gatgatcaaa attggaagaa ttgcaccgat cagaccgatc cagccacctt caaggaaaaa
     2041 cggccagcga atatatccat tttttgcacc gactaaacgc atgatttgaa tttcacgctg
     2101 tctagacaaa atcgtgatcc gaatcgtgtt cgaaatgaga aacatcgcta cgaacagcag
     2161 caatgccgct gcaactaatc cccatgtccg aactgcacca gcgatttgga aaatccgatc
     2221 tgaggaagct ccaccgtaat cagaacgaga aacattcttc aaatctgctg cttcttctgc
     2281 tacttgtttt gtataagaag gatcagtagc acttactaca tacacatcat ataacgggtt
     2341 attgtcacct tcaaacaatt tccaggaatc acccatttcg ttttggattt ttttcaattc
     2401 ctgttctttg cttgaaaatt caactttttt aacatgatct aagtcattca attctttttc
     2461 tagctttttc atctcttcgt cttttgtacc gatatctacg aatacagata catcaacgtt
     2521 tccttctata tcctgagcta atttagttgc attcatgata actgccatga atacaccgac
     2581 taaagtcaac gtgatcgtta ccgcactgac tgaagcaact gtcatccagc cgttacgttt
     2641 caaactcttg atactttcta ataaatggcg gaaaaaggtt ctaatcatcg tatccatatt
     2701 ccccttccgc ttgatctcga ataatgcggc cgttttcgat agcaattact cggtgccgaa
     2761 tcgtatttac gatcgtactg ttatgtgtag ccatcacgac agtagttcct tgggcattga
     2821 tccgatctaa taatttcatg atttcccatg agttttctgg atccagattt cctgtcggtt
     2881 catccgcgat aagtacttta ggcgtattca cgattgcccg agcaatagag acacgttgct
     2941 gttccccacc ggataattcg ctaggaaaga ctcgaacttt gtgtttcaaa ccaacaaggt
     3001 ccagcacttc cattactcgt tttttgatat ctcgaggttt tctgccgata acttgcatag
     3061 cgtacgcaac attttcatat actgtttttc ttggtaataa tttatagtct tggaacacca
     3121 cgccgatttc tctgcgtaga taaggaactt cgcggttttt gattgctatt agatcatgac
     3181 ctgcgacgtt caaagttcct tttgaagctt tttcttctcg atacatcaat ttgatgaatg
     3241 tagatttacc ggctccagac ggaccaacca catagacaaa ctctccttgt tcgatgacaa
     3301 tcgagagatt gcggatagcg gtcgtaccat ttgagtactt cttcattaca tccttcattt
     3361 caatcatggc gttctctcca tatctttttc agtctttagc tattatagca tggcaatgtt
     3421 tcaacatgct tgcaaaatct tacaatttta tttcaattta acaatgggtt cttattgtag
     3481 atgcattttt aaatagccgt caataaataa atcaaggtca ccgtccataa ctgcttggac
     3541 atttcctgtc tctacgtttg tccgatggtc ttttaccata gaatagggat ggaaaacata
     3601 agaacggatc tgtgaacccc agccgatttc tttttgttct cctcgaagtg cagctgcttc
     3661 ttgttctttc ttttccactt ctaattgata aagcttagct tttaacatcc ccatcgcttg
     3721 ctcacggttt ttcaattgtg agcgttgtgc ctgactagct actactgttc ctgtaggcaa
     3781 gtgagtgatc cgtacagcag attctgtttt attgatgtgc tgaccacctg caccacttgc
     3841 tcggtacgta tcgattttca aatcatctgg attgatttct atatcgatcg tttcatcaag
     3901 ctctggcatc acatctaccg aacaaaaaga agtatgacgt cgtttcgctg agtcaaaagg
     3961 cgaaatccgt acaaggcgat gaacaccttt ttctgatttt agataaccaa aagcgttatg
     4021 tcctttaatc agcagggtca cactcttgat ccctgcttca tcacctgctt gataatctag
     4081 tgtttctact tgatagccat gctgctctgc ccaacgtgta tacatacgta aaagcatgct
     4141 gccccagtct tgggactccg ttccgccagc ccctggatgc aattcgacga tcgcattgtt
     4201 tcgatcataa ggtccgtcta acagcataga taattcatac gtcttcattt tttcatctaa
     4261 tgcattgata cgtgtttctg cttcttcttg cattgctgca tcaggttctt cttgcagcat
     4321 ctccaccatc aattcgattt cttctagttc ttcggcaaga gaatggaatt ggtcataggt
     4381 ttctttatta gcgttatttt cgctgatcac tttttgtgcg gcttcgctgt catcccaaaa
     4441 accaggttca gccatttttg cttctgcttc cgcgatgtct tcttccagct gatctaagtc
     4501 aaagagacct cctgaaactt gtgacctttt cctgcatttc tgtcaggaga tttcgaattt
     4561 cggatatttc catgtttttt ccttctttca ctatactttt ttcattatat ctagtctaac
     4621 agaatcagca aataacagaa agaaggtgag acgaattctt aaaaaaagaa tttgtctcac
     4681 caatcctgct gtcagaaatt agtttgcatt ttttccatga cagttcttat attttttccc
     4741 gcttccacaa ggacaaggat catttcttcc gaccttattc acatggattg gctgtttttt
     4801 cgcgctagta ttactatttt ctttggcatc tccgtcttct gagtgagaag ctgttccttg
     4861 agaaacctgt tcacgctgta cgttttgacg gatctcagct ttcataaaga ttcgagtgac
     4921 ttcatactcg atggcgccta ccatatcttc aaacatctta tagccttctg tttgatattc
     4981 gactaatgga ttgttctgtc cataagcacg taagccgatt gactgacgta attgatccat
     5041 tgcatcaata tggtctgtcc atttagagtc cacaacacgc aagatcacga ctttttcaaa
     5101 ttccaacagt tgctctggac catttagttg agccgctttg gtattaaata cttcttgtgc
     5161 tcgttcgttt agatactctt tgatctcctg agctgttttt ccttcgatat ctgcaagagt
     5221 aatgctatct tcatggacaa gagtactgcc ggcaaaatcg atgatacttt ccaaattcca
     5281 attttctttc tctaattgtg tatgcgcatc tactacacga ctgattgtcc gtttgaccat
     5341 gttcattagt ggcttggata agcttttttc ttccatgatt acttcttgtc gctgtttata
     5401 gattacttca cgttgttcac gcatcacatc atcgtattgt aagacgtttt tacgtgtgtc
     5461 atagttattt ccttctacac gtttttgtgc agattctact tgtttcgtca gcatcttgct
     5521 ttggataaca gcatcttcct caccgatctt catccgatct aagaaagctt tgattcgttc
     5581 tgaaccgaat cgtttcatca aatcatcttc caatgacaag tagaactgtg acataccagg
     5641 gtctccttga cgtcctgcac gtcctcgaag ctggttatcg atacgacgag attcatgtcg
     5701 ttctgtcccg ataactgcta gaccaccaag ttctcttacc ccaagtccta acttgatatc
     5761 tgttccccga ccagccatgt tggtagcaat cgtcacagca cctttttgac cagcattcat
     5821 gatgatctct gcttctttaa agtgattttt cgcattcagc acttcatgag gaatacgttc
     5881 ttgattcagc atatctgata ataactcaga tgtttcaacc gcaacagttc cgactaacac
     5941 aggttgacct ttgcggtagc gatctttgat atcttgcacg acagcgtgga acttgctttg
     6001 taatgttggg taaagcaaat ctggacgatc atcacggata accggacgat ttgtcggaat
     6061 ctggtatact tggatgttat aaatttctct gaattcttct tcttctgttt tagctgtacc
     6121 agtcattccc gcaagtttct tgtacatacg gaaatagttc tggaaagtga tcgtcgccat
     6181 ggttttcgtt tcgtcttcga tctctacgcc ttctttagct tcgattgctt ggtgaagtcc
     6241 atctgaataa cggcgtccat ccatgatccg accagtgaac tggtcaacaa tcagtacttt
     6301 tccgtcttgg acaacataat cgatatctaa aagcatgata tagttggctc tcaatgcttg
     6361 atccaagtga tgggtcaatg cagtattttc aatgtcgtat aagttatcca aaccgaatgt
     6421 ttcttctgct ttttcgatcc ctgcttcggt taaactgatt gtttttgatt gtacatcgat
     6481 tttataatct tcttcttctt tcaaacgttt cacgaagttg tctgctcttg tatataaagc
     6541 tgtggatttt tctgcttgcc ctgaaatgat cagcggcgtt ctcgcttcat caatcaagat
     6601 tgagtcaact tcatcgacaa tggcataatt cagcggacgt tgtaccattt gatggcggta
     6661 aacgaccata ttgtctctca agtagtcaaa tcctaattca ttattcgtac tataagtgat
     6721 atcacaatta taagcctcgc gtttttcatc cgaagatttt gagttgatat tcaaccccac
     6781 tgttaatcct aagaaattat aaagttcgcc catttccgtc gagtcacggg ttgctaaata
     6841 ttcattgacg gtaactacgt gtaccccttc gccagtcaga gcatttagat atactggcat
     6901 cgttgcggtc aaggttttac cttcaccagt acgcatttca gggatatttc catcgtgaag
     6961 cacgattcca cccatcaatt gtacgtggta tggatataaa cctaatacac gttttgctgc
     7021 ttctcggacg actgcaaaag cttccggaag taattgatct aatgtttctc ctttttggta
     7081 tctgcccttg aattcagcag tttttgcctg taattgttca tcagttaatg ctgccatttg
     7141 gtcagcgtat gcttcaactt tttttgcaat gctatctaaa cgttttagtt ctttcttatc
     7201 gttttcgata agtgaacgaa tcaaattggc catgcgttgt gtaatctcct tttccttctg
     7261 tgtattatcc agactatgta gactttactt ttcattttat ca
//
LOCUS       DAFLWC010000115         6984 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.119, whole genome shotgun sequence.
ACCESSION   DAFLWC010000115 DAFLWC010000000
VERSION     DAFLWC010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6984
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.119"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            161..1033
                     /locus_tag="L1V17_002635"
     CDS             161..1033
                     /locus_tag="L1V17_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBN1237342.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            1030..2988
                     /locus_tag="L1V17_002636"
     CDS             1030..2988
                     /locus_tag="L1V17_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1237343.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(3320..4171)
                     /locus_tag="L1V17_002637"
     CDS             complement(3320..4171)
                     /locus_tag="L1V17_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1237344.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            4294..4761
                     /locus_tag="L1V17_002638"
     CDS             4294..4761
                     /locus_tag="L1V17_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBN1237345.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(5024..5506)
                     /locus_tag="L1V17_002639"
     CDS             complement(5024..5506)
                     /locus_tag="L1V17_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBN1237346.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(5606..6469)
                     /locus_tag="L1V17_002640"
     CDS             complement(5606..6469)
                     /locus_tag="L1V17_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBN1237347.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
BASE COUNT         2098 a         1435 c         1264 g         2187 t
ORIGIN      
        1 acgttaacaa taattcgttt catgtgacta gatcatacta ggcatgaaaa atctctgagg
       61 aacatggttt ccctaggagg tttttcgtgt ctatttttgt ttggccgcaa tcaactggtc
      121 tagcaaacgt gaaaaccaaa tcttcaaaaa gggtgcgcgc atgaaaatca aaaagatctt
      181 taatcaaaat gcagtattgg tagatgacgg tggacaggaa aaagtagcta ttggaaaagg
      241 gattggattt gacagaaaaa gaaatgattt gatttttgat cgtgatgtcg aacggatatt
      301 tgtcatggaa ccagaaggtc aaatcaagtt gcaaaattta cttaatcaga ttgatgaacg
      361 ctttttattt gcagcagaaa cgatcattga tcatgcggaa actgttttga tggaaaagtt
      421 gaatgaacat gtattgatcg ctttgaccga ccacattgct ttttctgcgg agaacattaa
      481 taacggtatc gtcatccgca acaaactttt aagagaaatc gaagtgcttt acagtgatga
      541 attcagtatt gctcaatggg cagtagagta tctgacaaaa gagcttggga ttccatatac
      601 ttatgacgaa gcaggatata tcgcaatcca tattcacagc ggacgaagcg gtcggaacaa
      661 taaccatcgc agtatccgtg aagtgacgat tgtatctgac atcatccatt tagtggaatc
      721 agaattggaa acagatatcc attcagaacc attttcactg aattattcaa gactggtgaa
      781 tcatttacga ctgcttctac aacgaaccca tgcgcaacaa tatgctgttt tagacacgga
      841 aatcgtagaa atggtcaaac gaaaataccc agaaagctat aagatttcta aaaaaatccg
      901 tgtgttgctg accaaagaat accagctcgc gatcacgaaa gaagaactgg gttacttggc
      961 catccatatc gagcgtttaa gaagcgcaat cgtacaaaca aatgttaaca atcatgagga
     1021 ggaaaaaaat tgaaagcata tctacaacga atgggacgtt cccttcaact tccagttgcg
     1081 gtcttacctg ctgctgcttt actagtaggg atcggaaact ggtgggcatc ttatagtaac
     1141 gacattgtcg ctcatttttt acaagctggc ggtaacgcag ttttaggtca attacctttg
     1201 ctgtttgccg ttgggttagc actagggatg tcagtggaca aatcaggtgc tgctgccttg
     1261 gcaggtttgg tcgcatttga agttccagta aatgttttaa aaactgattc agtagctact
     1321 ttattgaata tcaaaccaga atcagttgat ccatcttttg ctcagatcag taacgtattt
     1381 attggtatta ttgccggatt gattgcggca gctctttata atcgtttcca cgaagcaaaa
     1441 ttaccgatgg ctttatcttt ctttagcggc aagcgtctag tgccaatctt ggctgccttt
     1501 gtcatgttgc tgatcagtgc agtgctactg ctcgtatggc ctccggttta ctctgcttta
     1561 gtttcttttg ctaaattcat tttgagttta ggctggggtg gtgcaggtct ttatggcttc
     1621 ttcaaccgtt tactgatccc tacaggattg catcaagcaa tgaactccgt gttctggttt
     1681 gacgtagcag gaatcaatga tattggtaaa tttttggctt ctgaaggaac aaaaggcgta
     1741 acaggaatgt atcaagctgg atttttccca atcatgatgt tcgggcttcc agcaggagca
     1801 tatgctattt acagaaatgc acgtccagaa aacaaagcaa aaacagcttc cttgatgtta
     1861 gcagcagctt ttgcttcatt ctttactggt gtaacagaac cacttgaatt ctcatttatg
     1921 ttcgttgctt ggccattata tgtcttgcat gcaattttca ctgggatttc tttagcagtg
     1981 agtgcattct tccattggac agcaggattt gcctttagtg ccggatttgt cgattacttc
     2041 ctatctttga aaaatccgat tgcgaatcag ccattgatgt tgatcgtcca aggattagta
     2101 acagcagtga tttactactt tggctttaac tttgctatca aaaaattcca tctgatgact
     2161 cctggccgcg aggaagcaga tctttcagat gacgatactg caacgactaa ttcagacaat
     2221 aaatatgcgg cacaagcaag caaaatctac gctgcattag gcggagccga caatgtaact
     2281 tcgatcgata actgtactac acgccttcgt ttgcaagtca aagatacagg cctgatcgat
     2341 caaaataaaa tcaaagccac tggcgtacct ggtatgaaga tcatcgacgg aaaaaatgcg
     2401 caagtcatcg taggtacaga agtacaattc gttgcagatg agatggcaaa actacatggt
     2461 ggtgctgcaa cacgacctgc acaaacaaac accgtggtta aaacagaaac atttgccggt
     2521 ggaacgatcg aacaagatat ttacgctatc gcaaatggga aactgattcc aatcactgaa
     2581 gtttcagatg atgtattcgc ggaaaaaatg atgggtgacg gctatgctgt attaccagaa
     2641 aatggagaaa tcttctctcc aatcgctggt acgatcacaa acattttccc aacgaaacat
     2701 gctgtcggaa tccaaacaga tgctggtatc gaagtcttgc ttcatatggg catcaacact
     2761 gttgacttaa aaggcgaacc attcacttta tatgtaaaag aaggtcaaaa agtcgcaaga
     2821 ggtcaattga ttgctttagt tgatcttgcc gctattcaat ctgcaggcaa aaacacggat
     2881 atggtcgttg tattcacaaa tggcgacaaa gtccaaagct tagaaatcga acccgcacgt
     2941 gatgtaaaag caaatgataa aatcggctct gtttccaaca aagcctgagc catcgtcttc
     3001 cccagacttt tttatcgata aacaaacagg agctgagaca aaaatcttgt ctcagctcct
     3061 ttttccgaat aaaaacggcg ttctcctgcc aactccgcgg taataagtcc agccaaacgt
     3121 aacatatgaa gagctatttt ttatttgact cttcttatta cttgatgcag aacagctttt
     3181 ttacaacctc tgataaacgg tgttcaaaaa ccagtttatc ggtatgaagt caaatttatg
     3241 caaaaatgtg gaaagccatt ttcacaaaat ttttcttcat actcaaaact aatcggcttt
     3301 ttcacaacct ctttatacat tattcctgat ccaatatttc ttttaatgct gcttcaagag
     3361 aagttaatgg ttttcccaat actttttcta aatcatcaga ggaaatagct aactgatcct
     3421 ttttaatatc atgttggatc gctaaaaaca tgtcagctgc ttcttgaggg aatccggctt
     3481 cttttagatt ttcgacaaac gctgcatcac ttgcttcaat aatttctaac tttttacctg
     3541 tcgcacgctc taatgccttg gctaattctt catagtcagt tagattgccg gataattcta
     3601 agatttctgg agagtcactt tctactagta cttttgctgc agcttctgca tattcacgtt
     3661 tcaatgccca acctgttttt ccatttcctg cagcataaac gaattgacca gtttttaaag
     3721 cctgcccaat gataggtaat tcattctcta cataccaatt attccgtaaa aatgtatggg
     3781 aaatacctga atccttaatc attttttcag tgaattggtg atctggcgct aatacactga
     3841 tcgagtgatc ggcatctgca aaacttgtat aagcgatata agatacccca gctgcttgtg
     3901 ctgccttcac tacattctta tgttcggctt gacgatttcc tggaacgcca gagacaaaaa
     3961 gcaatcgatc tattcctttc aacgcttctt tcattgagtc taaatcatca taatcaccaa
     4021 tacgtatatt aaatccagct tctttcagtg cttctccttt ttcttcacta cgtactagta
     4081 catagatttc attttgtgga accatctttt ttaagaattc cagcgcataa ccaccaaaac
     4141 ctccagttgc tcctgttact aaataatgca tatttgccac tccctattct ttttatttgt
     4201 taagatttac agctgtacat ttataaatta cacctttatc ataaagagtg tggtaagata
     4261 agtcaagcaa aaaaaatgaa aggatgacaa ctgatgaagt attctctgca atttagtgat
     4321 gcaatccatg tacttgccta tattgaaatg tttcaagata cccgatcact ttctagtgag
     4381 atgattgcca gtagtatcga aacaaatgca gcaaatgtac gtaaaatcat gagtcagctc
     4441 aaaaaatccg gtttgatctt tacaaaaacc ggaaaaccgc agccttccct tgccaaaagt
     4501 ccagatcaga tttctttact agatgtctat cgcagcatcg aaggtaatac acagcttatc
     4561 caagtcgatc caaaaacaaa tccaaattgc gtcgttggtg cgaatatcca agaagcttta
     4621 gaagaaagct acgctcggct gcagaaaaag gcagaagaag aaatggctaa gatcacactt
     4681 gatagtctga tacataaaat agccgttttg gaaaaagaaa aaagaccaga aaacacaggc
     4741 ctcgtagaga gatttttata attctctcta ctgtgcctgc atttttctga tcggaatcgt
     4801 ctacataaat tcttttattc tccgggggac aaaagccttg tcatgcccct ttttcctctc
     4861 taatgctcag gtcaaagcgc tgaagtcatg acgtcttgat aaacggtgtt caagtagctg
     4921 accctcggca ttagttctga aaaatgcaaa atatggaaag ctatttccca tttttcctct
     4981 ctaatgctca ggtcaaagcg ctactttcac gacctctata ttatcatggt ttattgacta
     5041 ccggtatcca gatttctccc atatatttcc cgttggtaac tcccatttcg actacagcat
     5101 ttggaccccc aacataggcg taatcttcta cttctcttaa aacatgccca aaggccgtat
     5161 tcgtcaaatc atttcttaat tcttcaggcg attctgctaa agcgattaca acaagatacg
     5221 ttccttttgg gaatgggatg attcgggtag tgtttggaac atcctgactc gtttgaacac
     5281 cgacatagta catcattttc ccgttatagg gttcgttgac tgtaaagaaa taatgatttt
     5341 cagcagcttg tttcaatgca tctattgttc cattaccgat aactttttgc tcaaatgctt
     5401 gtttctctgc agccaaaccg acaaaatccg tattgctact cttcaattcc acaccaatac
     5461 ccgtcaccgt aaaatctggt ttttcttcga tcctatactt tgccatttct cccacccttt
     5521 ctattatatt aagttcatct tacataaaat taaagggaaa tgacacgatt acgctctttt
     5581 ttctagggat atttttattt tttaactatt tttttgcttt cactgcaatc caaatctcac
     5641 tgtaaacatt actgaaatcc tctccccatt ttgtaaaaga gatctcggga gcttcgacta
     5701 actcataatc tgaagaagga agccattctg catagatttt cccccaagta tcttgtaaag
     5761 tttggggaaa tggcccttta ttaggaaaaa tggcccaagt gtgttcttct atagcaagca
     5821 tttctaaatc agcgtacgga ttttcttttg tcgtagcaaa gccaatcatg tgcatcaaac
     5881 tgcccttttc ttccaagcgg gctccatcaa atccataaga aacgttgatt acttgatttg
     5941 gatataaatc tcctaactta tgcatctctt ccctttgagt ctccgtgatc gtctgcgcta
     6001 acttttgtat ttcttgattg actccttcaa atttgacagg aacttttttc gccacacctg
     6061 ccacataaaa ctgttctttc ttttcgatac gaaattccat cgattttcct cctctgacat
     6121 caataaaaaa tgtcaagcgt ggaaaagatt tttgtatgcc gtatctgctg atttctgaag
     6181 gcagatatcc tgaccaatca cgaaaagctc ttgaaaaacc ttcgactgtt tcatatccat
     6241 atctaaacgc cgtttctgtc actcttgatc catctaggag atcgcgatta gccaaagcca
     6301 atctacggtt tttgatatag tccattagcg acatccctgc aataaacgta aagatgcgtt
     6361 ttaattgata ttcagagatt cctgtatttt cggctattat tttataggaa agtccttctg
     6421 tcaaatgttc ttcgatgtaa tcgatcaatt ggttcagatc tttaagcata tttatcttcc
     6481 tccttgcttg cctttttatc atattatcaa agaaagtcaa ttacttgatg aatcaggaac
     6541 caatttagtc agatgtagaa aatgttgtat ggatctaaag aaaattctca agcagcgttt
     6601 cgtaacggat aattggtatt atctgcctat ctatgtttta cctttagaaa aataaatttt
     6661 ggggaagaca cattctaagt aaacaaagcg gtaaaaatat cttttattcc cttagttaat
     6721 ccgcttacta cctactgtac aaagcaaatt gttgttcaaa ctgctgatca gaacgctgct
     6781 tggatttttc tttgcgatac atcatacctc ttttatcaat tggaacaatt atttatttct
     6841 aacaaaatca cttcattttt gtcagataaa taaaaaacaa aaaaagttcc atctttaaaa
     6901 cacgctattc ttttactttt tctcacattc tctaagaaaa gaaaaggaga atgaattttt
     6961 gacaattcga gcaaaagtga ttat
//
LOCUS       DAFLWC010000116         6939 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.120, whole genome shotgun sequence.
ACCESSION   DAFLWC010000116 DAFLWC010000000
VERSION     DAFLWC010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6939
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.120"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..182)
                     /locus_tag="L1V17_002641"
     CDS             complement(<1..182)
                     /locus_tag="L1V17_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBN1237348.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
     gene            517..951
                     /locus_tag="L1V17_002642"
     CDS             517..951
                     /locus_tag="L1V17_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBN1237349.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            974..1294
                     /locus_tag="L1V17_002643"
     CDS             974..1294
                     /locus_tag="L1V17_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237350.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            1435..1626
                     /locus_tag="L1V17_002644"
     CDS             1435..1626
                     /locus_tag="L1V17_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237351.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(1697..1954)
                     /locus_tag="L1V17_002645"
     CDS             complement(1697..1954)
                     /locus_tag="L1V17_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HBN1237352.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            2112..2375
                     /locus_tag="L1V17_002646"
     CDS             2112..2375
                     /locus_tag="L1V17_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237353.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            2399..2587
                     /locus_tag="L1V17_002647"
     CDS             2399..2587
                     /locus_tag="L1V17_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237354.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(2670..2855)
                     /locus_tag="L1V17_002648"
     CDS             complement(2670..2855)
                     /locus_tag="L1V17_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237355.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            3070..3441
                     /locus_tag="L1V17_002649"
     CDS             3070..3441
                     /locus_tag="L1V17_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBN1237356.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(3591..3663)
                     /locus_tag="L1V17_002650"
     tRNA            complement(3591..3663)
                     /locus_tag="L1V17_002650"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3628..3630),aa:Gln,seq:ctg)
     gene            complement(3709..4137)
                     /locus_tag="L1V17_002651"
     CDS             complement(3709..4137)
                     /locus_tag="L1V17_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237357.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(4197..4850)
                     /locus_tag="L1V17_002652"
     CDS             complement(4197..4850)
                     /locus_tag="L1V17_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBN1237358.1"
                     /translation="MNTAQKSSTQKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTS
                     LSMLLSFYGYETTKNQLAEQLDYVPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPV
                     ASLAQQIVQTDYHTFPKTDAQLDDIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNN
                     GEVRVTPLVHACVVTGYDKENIYVNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            5249..5446
                     /locus_tag="L1V17_002653"
     CDS             5249..5446
                     /locus_tag="L1V17_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237359.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            5552..6034
                     /locus_tag="L1V17_002654"
     CDS             5552..6034
                     /locus_tag="L1V17_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237360.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(6092..6688)
                     /locus_tag="L1V17_002655"
     CDS             complement(6092..6688)
                     /locus_tag="L1V17_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBN1237361.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAEEKEYMNDADRFRVFG"
BASE COUNT         2350 a         1064 c         1357 g         2168 t
ORIGIN      
        1 gaatttgatt ctgcaatggc attgatcaag gagttatcac caacgtattt ttgagaaatc
       61 gttgatagag tatcacctga ttgaacggta taagcttcgt ccgcatgagc agtcgttccc
      121 atgaagaatg cagcgccggc agccaaagtt gttccaaaaa gtaaagtttt aagtgatgtc
      181 atgaaaaatc tcctttattc gttaaaaagt tttatttgtt gtgttcaacg aggaatactt
      241 taacacgtga aaatatttca taggtaaaag aagcatgaca atttatgaca aatccacgtt
      301 ttttgtaaca gaatgatgtt cgctcgatgt gaaaaatgat gaggaatttc acataatgca
      361 gaaataatgg gattagaaca ggtgttctga tgagaaaaga aatgtataaa taacttgaaa
      421 gaaattgctt ttgttcatca ttttatttac atattgcgta tattttttgt atttttgctt
      481 gagatgttac aataaaagaa aaaggaggcg gttccaatga gtaaaagata ccagaacatc
      541 atggtagcag ttgacggatc aagacaatcg atcaaagcgt tcgctgaagc ccttgactta
      601 gcaaaggaca atgaagccca cttatttatc gtgtcaatca tcaacaaagt tgagctgacc
      661 catagtgcct atgccttttc aaaaatctat gcagatgaaa aacaaagaac agaagtagcc
      721 atgctgaaaa aaatcaatga tgccaaagag tacggcattg ctgagatcca cgcaatagtt
      781 gaaactggag atccaagaaa tttgattgcc aatgtcatcc ctggacaaga aaatattgat
      841 ttgatcgtta tgggagcgac aggaaaaggt gctatacaac aagcattagt tggatcgacc
      901 gcttcttatg tcgtatcaca tgccccttgc agtgtgttgg tcgtgaagta atgagataag
      961 ggaggaatag aaaatggttc gtcctcaaga agtccgtgcg ccaaaagaaa aaatagaaat
     1021 tttagcaatt attgaagacg gcacacaaac aaagaaggga tactcgatcg ctttagtaaa
     1081 gtggaaagga aaaaaaggtg ttgctctgag atgggatgga gataaccaac aagataaagg
     1141 attccctgtc acagctaacg gttatcatcc agcgtggttt gttctgcctg ataaatttat
     1201 ggaattatac agctatgatt atgcaagagc cgcagcatca atcaaagcat tagataaatt
     1261 aacagaagag cagaatgaaa tggaggaaaa ataaaaaaga cgaaccaatc agcctttaga
     1321 aaactgatta gttcgaggag taaaaatgaa aaaaggttat ttgggatgaa actagaataa
     1381 tgcgtataac ttaaataaaa cttaaagcaa taaaatggca agagggtgag gcaaatggaa
     1441 gcaggaaaag tattacagga agtaaaagca ctatgtgcag ataaaaaata tgaagaagcg
     1501 aaaagcctga tcgaaaagaa caaagaaaat ttggaagaaa agtacccgat cgcacaagaa
     1561 tttatagaat taaaacaagg aacgatcctt caccgattca aacatttttt tggtataaca
     1621 gaatagaaaa aacgattaaa gatcggcaga aatttgctgc atctttaatc gttttctttt
     1681 taaacatgcg agggattcaa ttctgattct tatataaaaa atagatccaa ataataagaa
     1741 aaattactga aagcgtcaat tcgatgatgt gtgttattaa tacagacgtt gtttcccaat
     1801 gcctaaaaga aaaaatttga taagtaaaat atacagcagg taaagaggcc agtaaaactg
     1861 aaaacttctt ttttgtccat tttatgtaat agaaaagaat gcttatcata ataaaaaaag
     1921 gaatataaaa aacaaattga ccgatcgcga tcatactatt gcctccgata aataaagtcc
     1981 atgatacaaa ataacacttt gtgcgaaatg gcgcaagcag ttttgtggat ttatccggta
     2041 aaatctgtat cgattttgaa attagaggag aaacttgcta taatcaaagt gaaagaagga
     2101 gtgggatttt catggatcat gtagtgttag aaatcgattt gcatttgatc aataatattc
     2161 gggtgattta ctatgttgta agtaacagtg tcgaacaacg tgtactgacg aataaaataa
     2221 atggtatttt agcaaagaaa gacgttcacc gattcaataa tggtgaagga agttattata
     2281 gtatcccagt agaaaaaatt atttatacga cagtcaaagt cagagaagat ctagatacca
     2341 aaaaagcata tgaacctatt tttacaactt attgattgac agcagatgga ggaaaaaaat
     2401 gaatccatat gaacaactta ttcaagattt gatcgatgga aaaatcgaaa agattgatgt
     2461 aaaaagagaa gaattaatgg cttttcgaga agcgtggctg aagttggaga atcgtaaata
     2521 tgtggtggga aaagcctcac tgaacggcaa tgtgacttat cattacgatc cgacacgttt
     2581 attttagtat gaagtattca gaaaagaacc aaaggaggac gatgcagcag cattgtcctc
     2641 ctttgatttt acaaaagtga aagttttact tatttgaata gatttttaaa tttgtttttg
     2701 acactgtcga tatttacatc ttttaaaaga ttttgggctt tctctttata aggtcctaat
     2761 tgttctttat gttcttcgat aaatcgtttt gcgccatcga aattgccgtt cttaatcatt
     2821 tccttgactt tttgaaataa ttcttcttga ttcattttga acacatcctt tgctatcaac
     2881 atgatttttt acatggacaa aacgagaaaa actgatttat ccacacgtca ataatatcaa
     2941 ataacgatca tttttactaa aaaaacactc gattctcgct tctaaagtag gagaaaaatc
     3001 tccaacttgg gacggatgga atttctttaa ctgacccata tactgaatat ataacaagga
     3061 ggtagaaaga tgaaagtgat taaatatttg attggactgg cggcgattag tggtattttg
     3121 ctatttggac tgaaatatta tactgaagga agttatggag aaatccctgg tatacttgat
     3181 cagctaaatc cattagttga aaaaggagag gtctatgtaa agacacaaaa accagaggaa
     3241 gtaaatgaat atggtacagc aaggtatgtg cagaaagctg ctgatgccaa tgggaaagaa
     3301 cgaacggttg aatttaatgg tctttctgtg ttaaaagaaa atcattattt gaaaattagc
     3361 aataaaggag cacacataga aacgtatgag gaagttccta gagaaaaagt tccggagaaa
     3421 gcattagcaa ttattgggta aatcagtttt tgtattaaga atacgcccga ttttattatt
     3481 cataatttaa ttatgtaaac taaatacaag tagtaaaaat aatacaataa tccccctgca
     3541 aaaagattgt tcttttacag ggggttcatt ttttcagcaa gcacatcaaa ttgggatggc
     3601 agggttcgaa cctacaattg cttgattcag agtcaagtgc cttaccagtt tggctacatc
     3661 ccatttattc aacaaaataa tcatagcact ttcctaaaaa aacgcaagtt atttttcttg
     3721 atcggatagt tgttgcttta ctcgtaaaag gcggcgtact agtttctttt ctaatccagc
     3781 aggaagggca atcagttctg ctactgacaa gacggtgtcc aataactgat attctttgac
     3841 aggttcattc ataatatgat agatgtttgc taaacgttca atatattcaa agcgagtata
     3901 ctctgttcga gcaattagaa atttcaataa atcggtggct ttctcgtact cttgatctgc
     3961 gtaataaaca agagattgac gatacaattt gatttccagt tcattgaggg tagcaggtct
     4021 gcgacgctcg ttccactcat taatagagac tttaccttga acatttccct tgcagtcacg
     4081 gacaaaaata atcggaattt catttggatc cattttttta tgtgtgaatt tttccattat
     4141 ctacgctccc ttcaaaggtt tggtatcttg agtataaggg atttttgttt gaattactag
     4201 cttttctcca aagttagcat ctgtccaccc attgcagtga aaatcgccga aaaatcgttg
     4261 atcggtactg ctcgattttt tacaccatag ggatcgttga cataaatatt ttctttgtca
     4321 tatccagtga ctacacaagc atgaacaaga ggagtgactc ttacttctcc attatttgtg
     4381 gtccaagtca taaaatcagt ttcatctggg acttcaaaat tgatagtcac agaagtccag
     4441 acaggatttc ctttagatag tgcttttttg atatcatcga gttgagcatc ggtttttgga
     4501 aaagtgtgat aatccgtttg gacgatttgc tgagcaaggg aggcaactgg gggaacatag
     4561 acgaccatag cccagtctcc gccactgata tcaccaacaa atccttcatt aggatcgcca
     4621 tgagtcccat ctgcattgaa aacagggacg taatccaatt gctcagctaa ctggttttta
     4681 gttgtttcat aaccataaaa agataaaagc atagaaagcg aagtgacttc acagccattt
     4741 tctaaagaag gagaatcaaa ctggctctct aatggaacat ctagtaaaac ttctgctttc
     4801 tcttttgtct ttttcgtttt ttgtgttgaa cttttttgtg cagtgttcat tgtatgttct
     4861 ggagaatgga tatgtaggta ataacttgta ccgcttaata aaagagcagc tgtgccccta
     4921 gaaacaatag ttttttgaac gtttttttct tcatttgaaa tctccctttt cagctgttta
     4981 tctttcctat tataaatgta tttttattgg aaatggaagt attatatttt aatatgtagg
     5041 aaataattag tttttaagga atatgtttta attttttgaa aaaaattctt ctaaatacaa
     5101 cagctgtttt aattgtgaaa acgaaaacag tacgctataa tgcctgtaag gttgattttt
     5161 aactgtaaat aaaaatcaat gagttaaatc tccaaagaaa tagcagtggt aatgtggaga
     5221 aaagttccag cagtttagga ggattttgat gacggaagaa atgattaatt taggagaaca
     5281 atatgcatgc aaaccaattg gttttacaaa aacggtcatt ggtgaagttg tatcaaaaat
     5341 gacaaactgc gccgtggtca aagttgccca atgtgctgca gaggaccaag aattattaga
     5401 tgaaaaagca agcatggttg ttgcaaaata tgatacattt gaataaagaa aacaattgga
     5461 cgtgcggcgt gctgcaagtc caatttcttt gagaaggtaa atcagtattc ttttcctatt
     5521 ttctggagaa gaaaaagcga ggcgagttgt catggtaaca ttctttacgg ttctattgtt
     5581 tttattcgtt gttgtgatgt ttttatttct ttggctggtt cgaaaagaaa ttatttatcg
     5641 gactgtgcga aatcgatggg tctacttggt gatacccttc ttagtgtcac tagtcatttg
     5701 gtatacactc atcagtcatc ctacagcaga tgaattggca aaagggatct tgtcagcaat
     5761 gatttttatt agttttttgt tggacagtag aggaatcaca gaagaaggac ttgttttgaa
     5821 tagctttgac aaaaaaggtg ttcctttttc tgagatcaat aaaattgtat tatatcagcc
     5881 aaaaggttct aaaatcgtaa aaatgaattt tttccgaaac ggatggcgag gaccgatgct
     5941 gaaattttct gcatcattag aagaattagt tccatttttg tcccaacgct taaacgatga
     6001 ggcagagatt gatattatga ttgatccaga ataaaaacag aggttgcgac aagatgtttg
     6061 tcacaacctc tgttttttat ttcaaataaa attatccaaa tacgcggaag cgatcggcat
     6121 cgttcatgta ttctttttcc tcagccggtg tttctggtga accgaatact aattgcgaac
     6181 gtagtttcca gtttgaaggg atattccatt cttttgcaac tgcttcgtca ataactgggt
     6241 tgtaatgttg caagtttgcg cccaatcctt tatcaactaa tgctacccaa gtattagctg
     6301 ttgcgattcc gtttgattgt tctgaccaat ctgggaagtt gtctgcatat aattcaaatt
     6361 gttcttgtag accttttacc acgtcagtat ctttgaagaa taatactgta ccataaccat
     6421 ttttgaaacc agctaatttg ttttgtgtat ttgggaaagc ttctgctgga gtcaatgggc
     6481 gaagtgcttc ttcagtgatt tcccaaagtt tttcatgtgc atctccgaaa aggataactg
     6541 cgcgtgttga ttgagcattg aaagcagttg ggctttcttt aattgcttct ttgatcaaag
     6601 ttgttaattc ttcattagaa agtgaaacat tacgtcctag atgatagatt gaacggcggt
     6661 ttttcaaagt gtcagtaaaa gttgtcataa taaaatttct cctttgattt gcgttttgca
     6721 tttttttaat tgattacgaa atgaagtata gcaccttaca aaaagtaagt aaacagatat
     6781 gctcacaaaa aataagcgaa gttcaaaaaa caattttaat aagaaaaatc gttatgtaag
     6841 gattttctta gttatcgctt tcattgttgt gttttaggaa tttttgctta tttgaaaaaa
     6901 acagctgata tataattatt aaatctctat cttcttttt
//
LOCUS       DAFLWC010000117         6615 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.121, whole genome shotgun sequence.
ACCESSION   DAFLWC010000117 DAFLWC010000000
VERSION     DAFLWC010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.121"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            131..2806
                     /locus_tag="L1V17_002656"
     CDS             131..2806
                     /locus_tag="L1V17_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HBN1237362.1"
                     /translation="MKMNHTSIQKHLQLLNTLGISYVNLRTFSTLNKKTVSHIFSTAD
                     SQAIINYLEKQKLSEGTVNITYNPIKQEVITQKKHSVRDNDIEKIRFVFIDIDPKRKE
                     GSATDSEKKKAENVMEQVERYLKEKRIESFVKVDSGNGYHIFLPINEQPNNHETILTI
                     QNFLQLLHRRFGVEDEVDIDTSVYNPSRLCKLVGTPAVKGKSTKERPHRLSSFLSIPD
                     NIDRSNCFKILEQIVEENSMMSTSRVKSHPSFREVLPFIQADYKQWLAHYPELTYTIK
                     EGDHKGVTLLIFDECPLRKHTNNSNGSCLSVTADNKIRFHCLHASDKNKDIQDFVKKY
                     PLPKPVNPSVESLESNQEYYFDQFKLNQEGVFLVKEGQEEKVACPMFIKQIRKNIEQK
                     VITLVLAYYVDHCWDEIEIEGGCLQTNNFKQLAKHGLIIKARREAEVVDFLQIQRENA
                     PIFFEHESLGWKKENEAMIFQLQDSFGREIPSVLTKNSCYQLTTNGTEAEFDALVHKY
                     VLGTNLELAWSIGIASIVLGYLNVTKANTFLSLLINLQGKSTTGKTTTLHFIASLFGN
                     PTTVLRNMNATNKAIIKLASNNQGGVPLILDELGAATQNNFSSLIYQLASGEERLRLD
                     SNCQLMPQETFSVLTLTSSEERLENYFNEKLTGLKVRYIEFSDIKFTKDANHAEKVKS
                     LSSNTFGWGIKLFLLKLFEQGITKIEATFVEAQKKLWAVLPEHSLKQRIGNNLALIYS
                     GALLIQDILGYPLRLEHIQTVLINSYEQLIVDTSLGSEQTVFDRVKTLLVMNSHKFLT
                     NSDNKHTPSTIWGKVSIQKNGDIKVNIFPIPFEDLLRREFQVKDLTYLFRQLLDSGNM
                     CAEKGRRTKRIHMNRQVLPTYEILLPSSLKSYFRL"
     gene            2988..3227
                     /locus_tag="L1V17_002657"
     CDS             2988..3227
                     /locus_tag="L1V17_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237363.1"
                     /translation="MTKNKMTLKAEVLLYIQEHFSNQAFFTKPIYLDFEIRGVSAGSI
                     GGTLQALKNEGYLENHFVQRSFNRRVVKKWYLVHS"
     gene            3243..4616
                     /locus_tag="L1V17_002658"
     CDS             3243..4616
                     /locus_tag="L1V17_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1237364.1"
                     /translation="MRVACYDRTSVYEEAKISNDAQYDAVKEYVLEKYEQIPQRFSDK
                     GESGEKAERPAFRQLRAWVCASEEEGVIYVWRYDRLARQAKIALEFIELCQQHQVQVY
                     SISEPLPASFSHASTNKLFVQLLFTFAEQQRNVIIENVRAGLSYKKQQRQYLSSAVPY
                     GYRLVNGKIQQEVHEARIVRYIFQLYLTKKYGYKKLCQRLTQQKLFFRERPFQPYHIY
                     SILKNPLYYGEIKGGSLGKYLGTFEPILSKATFLQAQEIRQSRCTAKKDTYLYLLRQK
                     IRCPFCGRHLSSKYQWNTKKTKTLHYYHCTDRSCQGIFLRAERVESEVLEKIQAFFQY
                     EGVYQALIAQLTQQLAEKRKDEKRKVIQQKKQEAQWIKAFEEGNCSLEELKQQLQALQ
                     KPMSTSSFLSLQQCEAKVKEWLQLKDLSSRQLLCDYVCRIEVTKDKTVCGIYFRQLTQ
                     NILERNE"
     gene            4620..6254
                     /locus_tag="L1V17_002659"
     CDS             4620..6254
                     /locus_tag="L1V17_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1237365.1"
                     /translation="MEMIQTKRVALYIRVSTQEQALEGHSIQAQEQNGRQFAERMGYE
                     VVEVYADEGISGKSTKNRFAYQRMMNDARNHRFDLLVIWKLTRLGRNMLDVLQTVEEL
                     LRYDVGLHSISEQFDVTTSTGKLMLQLLGSFGEFERNQIAENVQMSMQSLVKDKKRYA
                     GGRRLGYVSGIDTNGQKQLVIEPEEAKIVRLIYAKYLGGAGYRAIANFLNRQGYQTVK
                     KNAFSTTAVKDILRNKIYAGYLEYARYINWETKRRKGKNPRPILVKGTHEPIISEEDY
                     QKVQERLALEGKQPKWNHTGENVLTGLLRCPECGAPMAASNVTNTLKDGTKKRIRYYS
                     CSVFRNKGASVCHANSIRAEQAETFVADRLKEIVQLPEVLPRLVAALNEEIVRQSQPL
                     EQELVVLLERKEELKTKIEKWEAALEDSPELFPMLKDRLDELTEKRRQLHIRENEILG
                     IFQQGEPIQVKDVQRILTSLDRFLAQSEKKQIKALYRTFIEKITFDPNHKEMLEITMK
                     FTHAVVQQLNEQYQIAVSKTKDTAIFVLKTPFTLTI"
     gene            6417..>6615
                     /locus_tag="L1V17_002660"
     CDS             6417..>6615
                     /locus_tag="L1V17_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237366.1"
                     /translation="MKKMGKCILCEKYTELTKEHVPPKKSGNTGGKKTRTGNLDDFLK
                     SDFTKGDFPKGIKRKPQGNVYY"
BASE COUNT         2317 a         1068 c         1330 g         1900 t
ORIGIN      
        1 acaacttttt tcttttgtca agattttgag tgggatatat ttttgtagaa ctgaagatca
       61 tgaaattatg agaggttgga ggtaatgtag tcatacaaat aaaaattttt tagaaagtga
      121 gtggtaatta atgaaaatga atcacacttc aattcagaag catttacaac tgttaaatac
      181 actggggatt tcttatgtta atttgagaac tttttctaca ttaaacaaga aaaccgtttc
      241 tcatattttt tctactgcag attctcaagc aattattaac tatttagaaa aacagaaatt
      301 gtctgaaggt acagtaaaca taacttataa tcctattaaa caagaggtga ttacacaaaa
      361 aaagcattct gtgagagaca atgatattga aaaaattcgg tttgtattta ttgatattga
      421 ccctaaaagg aaagagggaa gtgcaacaga tagcgaaaag aaaaaggcag aaaatgttat
      481 ggaacaagta gaacgttatt tgaaagaaaa gagaatagaa tcatttgtaa aagttgatag
      541 tgggaatggc taccatattt ttcttcccat aaatgaacaa ccaaataatc acgagacgat
      601 tcttactatt cagaattttc ttcaattact tcaccgaaga tttggagtag aagatgaagt
      661 tgatattgat acttctgttt ataatccttc aagattatgc aaattagttg gtacaccagc
      721 ggtcaaagga aagtccacaa aagagcgtcc gcatcgttta tctagtttcc tttctattcc
      781 cgataacata gatagaagta attgttttaa aattcttgaa cagatagttg aagaaaattc
      841 catgatgtca acctctagag taaaaagcca tccatctttt agagaagtgt taccttttat
      901 tcaagcagac tataaacaat ggttagctca ctatcctgaa ttaacttata ccataaaaga
      961 gggcgatcat aaaggagtta ccttacttat atttgacgaa tgtccattaa gaaaacacac
     1021 gaataattct aatggttctt gtttgtctgt tacggctgat aataagattc gatttcattg
     1081 tctgcatgct tcggataaaa ataaagatat tcaagacttt gtaaaaaaat atccgttgcc
     1141 aaaacctgta aatccttctg tagaatcatt agaatccaat caagaatatt attttgacca
     1201 gtttaaactg aatcaagaag gagtattttt ggtgaaagaa ggtcaagaag aaaaagttgc
     1261 ttgtccgatg tttattaagc aaatacgcaa aaatatcgaa caaaaagtca ttacacttgt
     1321 tcttgcctat tatgtcgatc attgttggga tgaaatagaa atagaaggtg gatgtttaca
     1381 aactaataat tttaaacaat tagcaaaaca tggcttaatc attaaagcta gaagagaagc
     1441 tgaagtcgtt gactttttac agattcaacg ggagaatgct ccaatctttt ttgaacatga
     1501 atctcttggc tggaaaaaag aaaatgaagc aatgattttt cagttacaag attcttttgg
     1561 acgtgaaatt ccttctgtat taactaaaaa ctcatgctac caattaacaa ctaatggtac
     1621 agaagcggaa tttgacgcat tggttcataa gtatgtttta ggaacgaact tagaacttgc
     1681 ttggtcgatt ggtattgctt ctattgtgtt aggctattta aacgttacga aggctaatac
     1741 ttttttgagt ttactaatta acctacaggg caagagcaca acgggtaaaa ccactacgtt
     1801 acactttatt gcctctttat ttggaaatcc aactacggtt cttagaaata tgaatgctac
     1861 caataaagcc attataaagc tagcatcaaa caatcaggga ggtgttccac taatactaga
     1921 tgagttagga gcagcaactc aaaataactt tagctcgttg atctatcaat tagcttcagg
     1981 agaagaaagg ctaagattag attctaattg tcagcttatg ccacaagaga ctttttctgt
     2041 tttgaccctt acctcttctg aagagcgttt ggaaaattat ttcaatgaga aattaactgg
     2101 tttgaaagtt cgatatatcg aattttctga tatcaagttt acaaaggatg cgaatcacgc
     2161 agagaaagtt aaaagtcttt cttctaatac ttttggttgg ggtataaagt tatttctttt
     2221 gaaactcttt gaacaaggga ttacaaaaat tgaagcaact tttgtcgaag ctcaaaaaaa
     2281 actatgggct gttttacctg aacattcttt gaagcaacgc attggtaata atctagcttt
     2341 gatttatagt ggagccctcc taattcaaga tatactgggc tatcctttac gattagagca
     2401 tatacagacg gtgcttatta attcgtacga acagttaatt gtagatacta gtttaggaag
     2461 tgagcaaacg gtatttgacc gagtgaaaac attgttggtg atgaatagcc ataaattttt
     2521 aacaaacagt gacaacaaac atacgcccag tacgatttgg ggaaaagtat caattcaaaa
     2581 aaatggggat attaaggtaa atatttttcc tatcccgttt gaggacttgt taaggcgaga
     2641 atttcaagta aaggatctaa cctatctttt taggcaattg cttgattcgg gtaatatgtg
     2701 tgcagaaaaa gggagaagaa cgaaacgtat tcacatgaat cgtcaagttc ttccaacata
     2761 cgagattcta ttaccttctt cactcaaatc gtattttcga ttgtaattta gaataaacca
     2821 aagtatgaaa gtgaggcacc atgttatgga aatatttctt attgatttag caaaacaact
     2881 gattacttat ctgtatgata gcgagcaaac ccaaacggaa gtaaatgaag cttgatctat
     2941 gcttcattta cttcattcaa tcaaacatga aagaaaggaa aattctaatg actaaaaata
     3001 aaatgacact aaaagcagag gttcttctgt atattcaaga acatttttca aatcaagcct
     3061 tttttacaaa accaatttac ttggatttcg aaataagagg ggtatctgct ggatctatcg
     3121 ggggtactct tcaagcgttg aagaacgaag gatatttaga aaatcacttt gtgcaacgtt
     3181 cgttcaatag aagagtcgtg aaaaaatggt atttagttca ttcatagaga ggggaatcaa
     3241 gcatgcgtgt ggcttgttat gatcgaacgt ctgtttatga agaagcgaaa attagtaatg
     3301 acgctcaata tgatgcagtg aaagagtatg ttttagagaa atatgaacaa attccccaac
     3361 gattttcaga caaaggagaa tcaggggaaa aagcggagcg tccagctttt cgacagctta
     3421 gagcttgggt ttgtgcgtca gaagaagagg gggtgatcta tgtttggcgt tatgatcgat
     3481 tggcacgtca agccaaaata gccttagaat ttattgagtt gtgccaacaa catcaggttc
     3541 aagtgtattc gatttctgaa cctcttcctg cttctttctc acacgcgtca acgaataaac
     3601 tatttgtgca attattgttc acttttgcag aacaacaacg aaacgtcatt attgagaatg
     3661 ttcgtgccgg actttcctat aaaaagcaac aacggcaata tttgtcttct gcggtaccat
     3721 atgggtatcg tttagtgaat gggaaaatcc aacaagaagt acacgaagca aggattgttc
     3781 gctatatttt tcaactttat ttgaccaaaa aatatggcta caaaaagctt tgtcaacgat
     3841 tgacgcaaca aaagcttttc ttccgcgaac gtccttttca gccctatcat atttatagta
     3901 tcctaaaaaa tccattgtac tatggcgaaa tcaaaggagg atctttgggg aagtatctag
     3961 gaacctttga accgattctc tcgaaagcaa cctttttaca agcccaagag attcgccaat
     4021 caaggtgtac agctaaaaaa gatacgtatc tgtacttatt acgtcaaaaa attcggtgtc
     4081 ccttctgtgg tcgtcatctg agttcgaagt atcaatggaa tacaaagaag acgaagacgc
     4141 ttcattatta tcattgtacc gaccgaagct gccaaggaat ttttcttcgg gcagaaaggg
     4201 ttgagtcaga agtattggaa aagatacagg ctttttttca atacgaaggc gtctatcaag
     4261 ccttgattgc ccaattaacg caacaattag ccgaaaagcg aaaagatgaa aaacgcaaag
     4321 taatccaaca aaagaaacaa gaagcacaat ggattaaggc atttgaagag ggcaattgtt
     4381 cactggaaga actcaagcaa caactgcaag ctcttcaaaa gccgatgtct acttcttcgt
     4441 ttctttcact ccaacagtgt gaagcaaaag tgaaagaatg gcttcaacta aaagacctct
     4501 ctagtcgaca attattatgt gactatgttt gtcggattga ggtaacaaag gataaaacag
     4561 tttgtgggat ttacttccga caactgacac aaaatatttt agaaaggaac gaatgatcta
     4621 tggaaatgat acaaaccaaa cgagtcgcat tgtatattcg cgtgagtaca caagaacaag
     4681 ctttagaagg acatagtatt caagcacaag aacaaaatgg acgacagttt gccgaacgga
     4741 tgggctatga agtggtagaa gtttatgccg atgaaggaat cagtgggaaa tccacaaaaa
     4801 atcggttcgc ctatcaacga atgatgaacg atgctcggaa ccatcgtttt gatctactag
     4861 tgatttggaa attgacccgt ctcggacgca atatgttaga tgtcttacaa acagtcgagg
     4921 aattattgcg atatgacgta ggattacatt cgatctcgga acaatttgac gtgaccactt
     4981 cgacaggtaa attgatgtta caactccttg ggagtttcgg tgaatttgaa cgcaaccaaa
     5041 ttgcggagaa tgttcaaatg tcaatgcaaa gcttagtgaa agataaaaag cgttatgcag
     5101 gaggccgacg tttaggctat gtcagtggta ttgacacgaa tggtcaaaaa caattggtca
     5161 ttgaaccaga agaggcgaaa attgttcgtc tgatctatgc aaaatattta ggcggagcag
     5221 ggtatcgagc gattgccaat tttttgaatc gtcaaggata tcaaacagtc aaaaagaatg
     5281 ctttttctac cacggcagtc aaagatatct tacgcaataa aatttatgca gggtatttag
     5341 aatatgcgcg ctacatcaat tgggaaacca aacgacggaa ggggaagaat ccgagaccga
     5401 ttttagtgaa aggaacccat gaaccgatta tttcggaaga agattatcaa aaagtacaag
     5461 aacgccttgc tttagaagga aaacaaccca aatggaacca tacaggtgaa aatgtattga
     5521 caggcttgtt acgttgtcca gaatgtggcg caccgatggc agcgagtaat gtcacaaata
     5581 ccctaaagga tggcacaaag aaacggattc gatattattc ttgttcagtc tttcggaata
     5641 aaggagcaag tgtgtgtcat gccaattcga ttcgtgccga acaagcggaa acatttgtcg
     5701 ccgaccgatt aaaggagatc gttcagctac cagaagttct tccccgattg gtggcagcgt
     5761 taaatgaaga aatagtgcga caaagccaac cattggaaca agaactcgtg gtgttactgg
     5821 aacgaaagga agaattgaag actaaaattg aaaaatggga agctgctttg gaagatagtc
     5881 ctgaattgtt tccgatgtta aaagaccgct tagacgaatt gactgaaaaa cgacgacagt
     5941 tgcacattcg agaaaatgaa atcttaggga tctttcaaca aggagagccg attcaagtca
     6001 aagatgtcca acggatattg actagtttgg atcgttttct tgcccagagt gagaagaagc
     6061 aaatcaaagc cttgtatcgt acctttatag agaaaataac ctttgatcct aaccataagg
     6121 agatgttgga aattacgatg aaattcacgc atgccgtggt acaacaattg aatgagcaat
     6181 atcaaatagc cgtatccaaa acaaaggata cggctatttt tgtgttaaaa acacccttta
     6241 cgttaacgat ctagtctagg ttatatcaaa caacgttaga ggggcgctaa cgcttctcta
     6301 gcgatttgaa atcgttagag aagtagttag ggaggtcctt atcataaata gggatattta
     6361 ttaatgaata tttgaaatat aattgtatat aagaattaaa aagagtgggg atagatatga
     6421 aaaagatggg taagtgtatt ttatgtgaaa aatacactga acttactaaa gaacatgtac
     6481 cacctaaaaa atcagggaat actggaggta aaaagaccag aactggtaat ttagatgatt
     6541 tccttaagag cgattttaca aaaggtgatt ttccgaaggg gattaaaagg aaacctcaag
     6601 gaaatgttta ttata
//
LOCUS       DAFLWC010000118         6420 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.122, whole genome shotgun sequence.
ACCESSION   DAFLWC010000118 DAFLWC010000000
VERSION     DAFLWC010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6420
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.122"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..177
                     /locus_tag="L1V17_002661"
     CDS             <1..177
                     /locus_tag="L1V17_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1237367.1"
                     /translation="YLLGMALAYSVGSLIKVNVSLDLFTILLAVGVSSVIGLVFSVMP
                     ASEAAKKDLIDILR"
     gene            578..1183
                     /locus_tag="L1V17_002662"
     CDS             578..1183
                     /locus_tag="L1V17_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HBN1237368.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            1199..1771
                     /locus_tag="L1V17_002663"
     CDS             1199..1771
                     /locus_tag="L1V17_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1237369.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2023..2280)
                     /locus_tag="L1V17_002664"
     CDS             complement(2023..2280)
                     /locus_tag="L1V17_002664"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237370.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIF
                     MIVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
     gene            complement(2406..3221)
                     /locus_tag="L1V17_002665"
     CDS             complement(2406..3221)
                     /locus_tag="L1V17_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237371.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELE
                     KYLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIA
                     RIDDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEAD
                     ENYNVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDL
                     EALLSANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
     gene            3738..5063
                     /locus_tag="L1V17_002666"
     CDS             3738..5063
                     /locus_tag="L1V17_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBN1237372.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLA
                     TVGVGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRL
                     NQIGIMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            5056..5406
                     /locus_tag="L1V17_002667"
     CDS             5056..5406
                     /locus_tag="L1V17_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237373.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTE
                     EVAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQDNKWGRLE"
     gene            5388..5573
                     /locus_tag="L1V17_002668"
     CDS             5388..5573
                     /locus_tag="L1V17_002668"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237374.1"
                     /translation="MGSIRMNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSF
                     YVEAAAGYHKYEYYIGY"
BASE COUNT         2214 a          986 c         1178 g         2042 t
ORIGIN      
        1 tatttattag gaatggctct tgcttatagt gttggttctt tgataaaggt aaacgtgtca
       61 cttgatctat ttactatttt actagcggtt ggggtatctt cggttattgg actggtcttt
      121 tctgtaatgc ccgcttcaga ggctgcaaaa aaagatttaa ttgatattct tagataaaat
      181 cagaatgaca agaatattta cgttctagat tctaaaataa aacacaaaga gaccaaccag
      241 gcaccctatt gtttctttgt agtatagaga tattctttgg cttgtaagag atcaatagag
      301 ttaggtgacc ggagttcgaa ataaaggaaa tttttgattg tataggagaa ttctttatcc
      361 ctaatattta gaattttgag tatgccatgt tgatgtttta gattctctat aaatatagag
      421 gtgtatcaaa ggtcaactag actgtgcaaa atagagacac ttgaaaaatc tatcgggggt
      481 cagaaactta atagtttttg acacataaac aaaatcgcga tataatgggg ttgagagtgt
      541 ttcataaact tatgtcataa agttaaggag atttcgcatg attttagaga ataaattggg
      601 attaaccaat caagttgagt tggctaaggt tgaagaaaaa ctcagtaaac aaaaagcgaa
      661 agaattgtac gattgtggaa aaataaatga aatcgaagtt ggtacattta aaggtttatc
      721 tgaaattcat gaatttctat tttcggatat ttacgatttt gccggaaaaa tccgatcggt
      781 caatattgca aaaggaaatt ttcgatttgc accagttatg tatttagaac attcgttaca
      841 gcatattgat cagatgccac aaacttcttt tgaagagatt atcaagaaat atgtggagat
      901 gaatatcgct cacccatttc gagaaggaaa tggccgaagt actagaattt ggctggatct
      961 cattttaaag gaagaattgc aaaaagttgt agattggaac ttaatcgata aagcagacta
     1021 tctttctgca atggagcgaa gtcccataaa cgatttggaa atacgctatc taatttccaa
     1081 tgctctgact gataaaattg acgatcgcga gttatatatg aaaggaatcg atgtcagcta
     1141 tttctatgaa gggtattctg agtatacgat agatgatttg taaaagtagg tggaccaaat
     1201 gacgaaatat ggatatgcac gtgtctcaac cgcttctcaa agtacaaaag aacaaattca
     1261 acagttgctt gagaacggcg tagagaagaa gaatattttt tcagaaaaat ttacgggtac
     1321 aaaacgggat cggccaaaat tcaatcagct gttggctggt ctgaagcctg gagatgaaat
     1381 agttgttacg aagcttgatc gatttgctcg taacacgaga gaagcattag agatcattga
     1441 acctttactc gatgataacg taacgatcaa ggttttgaat ctaggaacga ttgaaaatac
     1501 gtccatgggg cgaatggtga cacggacgtt gttgagtgta gcagaaatgg aacgtgatat
     1561 gattgtggaa cgtacccaag aaggaaaaat gtttgcaaga aagaataatc ctaatttcag
     1621 agaaggacgt ccgaaagcaa caatcacacc gaagaagagg cacgcatatg aactgcttac
     1681 ttcaggtaaa tcgtataagg aagttgaagc tataaccggt ttcagtcgca gtacgctttt
     1741 tagaataaag aagaaaattg aagaaagtta aaaaagaagt ctcagcgaac cagacaggta
     1801 aatacttaat gcgttctaga tatgagtcta ttagcatgtt gtgaaatata atattttttt
     1861 atttacttga tttctgctca aaaaatgtgt atggtaactg taaaaggtaa agtaattaaa
     1921 ggtatgctag ccacgcttac tatattagga taccatcata tatttataat gaacgatttg
     1981 ttcgtctacc aaacaacaca tatcgttcag cgtaagtcac gtttaggaac gtggcttttt
     2041 tagtgttatt atcgataaat aatctattga ctctattgat tttatctcca tatccctacg
     2101 gtgttgattg tctttagatc tttcatttaa gaaccaaata actatcataa aaatcagcac
     2161 tgctgctaat ataataaaca gcattcctat tgtgatatta cctattgatt ttaccataac
     2221 tacgattaaa gtaataatgg cattcaagtc tcctttgttc tctatatata aattagccat
     2281 aaatcatctt cctttcaaat taagatactt gtttgatacc aataaatagt aagcgtggct
     2341 agcatacctt tttctgtaat agcaagtgtt ctaatagtcc aaacttaatg atggaccgat
     2401 gctagttata gtacagtaat gttttctttc ttatctagat ttttagtaag ctctatcagc
     2461 aaatctaaca aatctgagtc cttttcagaa actaaattaa atctagtgtt tacaacaaag
     2521 ttttcatgtt ctatattgtt tagattattt gcggaaagga gggcttctag atcttgacat
     2581 tcaaatctat atgcatcgtc ataaatctta ctagaaggag tgcttaattc gaaattactt
     2641 attttctcat cttggaccaa gataaattta tagatagtat ctttttgtgt ttttctttta
     2701 aaaacacaac agagtgtgtt ataaggaacg ttataatttt catcagcctc attttttctc
     2761 cattcaaaca aatgataaac tgcaaccaag ttgccatcaa tttcatggac agtgctctcg
     2821 gtaacatcct ttaaagaact atcaagggct aatttatagt aactagagag aggaagtaaa
     2881 attgtcgatt tactgagatg gttatcgtct atacgtgcaa tcatacctaa atcaactaag
     2941 gttttattcc aggtgtttat agttttagtt gtcactccta gagactctgc tatggtattg
     3001 accgaatgcc aggaatcccc gccttcattc tttgccttaa aacagtaata cagatataaa
     3061 ttaatagctt tgttattcgg taaatatttt tcaagttctg ttggtagaat aaagtaagaa
     3121 tccttaatgt tttttctgaa ctgtctccag tctctgtagt tttgtttata aagttgtgaa
     3181 acggtttttc cacctttaga aagtcctgct atcttaacca atcttattgc tcctttcttg
     3241 aatctgtcat gatcatacag tattttttac ttgtagtcca gcaccttaat atattatcct
     3301 atgtaattaa tttcgtacta gatagtaatt attttttatt taattctcta gtcacttaca
     3361 aataagttat ataaactacg attaataaat tattacaaaa actattaaga aaacttctac
     3421 atacaactat tacaaaacta ttaagaaact gaatactcct attttttgtt tttaaggaaa
     3481 gttttttctt ttttgaattt cttatttttt tctaatataa ctaagcaaaa ctggataata
     3541 cgacacttat tttcaaattt tcacaagact aatagtaaat atccatttaa taaagtgata
     3601 caatgtgttg attttacaaa tcaacagaag aagtagggaa ataacttacc tatgcttctt
     3661 tttttgtaca tttaatcgat tcttctttac aaaaacgaac gtatgtttgt ataatgtgga
     3721 agaatggagt gttatttatg atggattatt caaaagagcc agtaaatgat tactttttga
     3781 tcgatatgaa aagcttttac gcaagtgtcg aatgtataga aaggaattta gatccattaa
     3841 cgactgaatt agtcgtcatg agtcgagcgg ataatacagg atcagggttg attttagctt
     3901 cttcaccagc tgcaaagaag aagtacggta tttctaatgt cagtcgacca cgagatctac
     3961 cgcaaccttt tcctaaaacg ttacatgtcg ttccaccacg catgaatctc tatattaagc
     4021 gaaatatgca ggtaaacaat attttcagaa ggtatgtagc agacgaagat ttattgattt
     4081 actcgatcga tgaatcgatc ttaaaagtga ccagatcaat gaatcttttt acgactgaag
     4141 gaacaagaag tcaacggaga aagaagctgg ctcaaatgat ccaggagaat attaaagaag
     4201 agctaggatt gcttgctaca gtaggtgtcg gagataatcc cttattagct aaacttgctt
     4261 tagacaatga agcaaaacat aatgatggat tccttgctga atggacgtat caaaatgttc
     4321 ctgataaagt atggaatatt cctgaaatga cagacctttg gggtattgga tctcgaatga
     4381 aaaaaagact caaccaaatt ggtatcatga gtattaaaga cttagctaat tggaatccat
     4441 acactattaa gagccattta ggtgtgattg gcttacagct gtattttcat gcgaacggga
     4501 tcgatcgaac agatatagcg atcccaccag aaccgacaaa ggaaaaatca tatggtaatt
     4561 cacaagtgtt accacgagat tataccagga gaaatgaaat cgaactggtg gtaaaagaaa
     4621 tggcggaaca agtagctatt cgtatcaggc aacataactg taaaacaggt tgtgtccatt
     4681 tatacattgg cacgtcgatc ttagaaacga gaccaggttt ttcacaccag atgaagatcc
     4741 ctataacaga taatacaaag gaattgcaga attactgtct tttcttgttt gataagtatt
     4801 atgaaggaca agaagtaagg cacgttggaa taacctatag caagcttgtg tacactgatt
     4861 cgcttcagct ggatttattt agtgatccac aaaagcaaat tgacgaagaa aatttagata
     4921 aaattattga caagattcgg caaaaatatg gttttacgtc gattgtacat gcttcttcta
     4981 tgttagaagg cgctcgtagt attactagaa gtacattggt tggtggccat gcaggcggcg
     5041 caggagggct taaaaatgat tgattataat gatcgtggac gtttaaagtg ggcaggtttt
     5101 tatttatctg atcatactga aaaaattgat gccgacaatg aacaacgagc caatcaaaat
     5161 ttggcaaaag aacaaatgac gactgaagag gttgcggaag tattgaacgc tgcagtcata
     5221 aaaaatagat cagtatgtat tcaaaaagaa gaacgaaacg ctgaaggata ctatccagaa
     5281 gatattgtta gcaagatctt aggtagtgat gagctgggga tctacgttgg aaaaaacaaa
     5341 gttcactacg acgaaatacg tcatatcgaa ttttaccagg ataataaatg gggtcgatta
     5401 gaatgaacat tatccagcaa tatgagctaa agtatataac ctttgatcag ctatcagaag
     5461 agatttgggg ttatggccag cgtttgataa atgaggttgg tgttgaacgc ttctctttct
     5521 atgtagaagc tgcagcagga taccataaat acgaatacta tattggctat taaagtgcaa
     5581 taaaattata tttcttttat gttttacatt ttgtatcaat tctgataaaa ttacctatag
     5641 gtaattaaaa aatataaaaa aactagttac aaccttagga cgttgtaact agcttgaagc
     5701 atactagagc taactaaaat agcactagaa agcaatgtta aacccgtcca acaaacttga
     5761 tttaacattg agaccagctt attcagctaa atatagttga ataagcttct tttgttttaa
     5821 aaaaacaaaa ggtgtactac gaataacgca agtaaaagaa atactattac aaccagtagg
     5881 ctacaagtaa gtattactaa acattgcgta gttagaacct ttgctctatt gtctaaagcc
     5941 acaaaattag agatcagctt tatgatgcta agagcgagct gcatccatgc ggacataggt
     6001 tcttttgaca ctattaattc tcctttttag gataagggaa attgctagta gttttttcat
     6061 tagcaccatc ccccttcatt tgattgagtc tagtgctgct gtgatagttt gctgtttaat
     6121 atgcttacat tcttattata acataaatga aacaaacaca tggttagagg tcgtatcaat
     6181 caaaatagtg tctcacaaac gatttattac ttactcctgc tgactaacgg actgttcttc
     6241 agtaactgta actatatgtt tgttaaaacc accattacct gtagataaaa accaatatat
     6301 ttactatact cactatatta aatatattta gtatagtaaa aactagaaac aataaaattt
     6361 gtgaatgttg tataccccca aacaatacac atattttgaa ggattaggat taataaagct
//
LOCUS       DAFLWC010000119         6305 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.123, whole genome shotgun sequence.
ACCESSION   DAFLWC010000119 DAFLWC010000000
VERSION     DAFLWC010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6305
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.123"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(99..1229)
                     /locus_tag="L1V17_002669"
     CDS             complement(99..1229)
                     /locus_tag="L1V17_002669"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HBN1237375.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="L1V17_002670"
     CDS             complement(1878..3080)
                     /locus_tag="L1V17_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1237376.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="L1V17_002671"
     CDS             complement(3140..3343)
                     /locus_tag="L1V17_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HBN1237377.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="L1V17_002672"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="L1V17_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4880..5692
                     /locus_tag="L1V17_002673"
     CDS             4880..5692
                     /locus_tag="L1V17_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1237378.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
BASE COUNT         1874 a         1297 c          996 g         2138 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaat
//
LOCUS       DAFLWC010000120         6245 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.124, whole genome shotgun sequence.
ACCESSION   DAFLWC010000120 DAFLWC010000000
VERSION     DAFLWC010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6245
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.124"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..136)
                     /locus_tag="L1V17_002674"
     CDS             complement(<1..136)
                     /locus_tag="L1V17_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylate--amine ligase"
                     /protein_id="HBN1237379.1"
                     /translation="MNAFKTALNNNEMEGKIIGADCSELAPALYMCDEKIVLPKVSES
                     N"
     gene            complement(190..2007)
                     /locus_tag="L1V17_002675"
     CDS             complement(190..2007)
                     /locus_tag="L1V17_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBN1237380.1"
                     /translation="MFILTRRRKIATLVFVDSLLLIAANIAAAKFMKPFVSIPMDLIL
                     ISIGLSIGFYLFYGSLFKVFTRINRYTNLREIIAIFSSLSASAASSILILLFINRRYS
                     LRLVIFAYLLSLLLIIGSRLIWRIYIETKNMRYVSADSAKNTLIVGAGEGGRILYNSF
                     LGSKTAQDIHVVGFVDDDPNKRNTYLSGKKVLGALKDIPELIEKYDIQMVTIAIPSLS
                     RKKLRRIFELVESARVKVNTMPSIEELASGKISVSKLKTIDVVDLLGRDEVKLDIESI
                     KDQITDKVILVTGAGGSIGSEICRQIIQFNPAKLLLLGHGENSIYLIDRELRTHHQNC
                     PTEIVPIIADIQDREKINEIMEQYHPDIVYHAAAHKHVPLMEYNPKEAVKNNIFGTKN
                     VAEAAKAAKVKNFVMVSTDKANNPPNVMGSTKRIAEMIVTGLNEEGCTKFSAVRFGNV
                     LGSRGSVIPVFREQIAQGGPITVTDFRMTRYFMTIPEASRLVIQSGALAKGGEIFILD
                     MSEPVKIVDLAKNMIRLSGYSEDEIEIIETGIRPGEKLYEELLLDKERNDEAVYEKIF
                     VGNIKGYSIQKVMDFVKSLPQDDEQLAKDIVTFANASNR"
     gene            complement(2021..2785)
                     /locus_tag="L1V17_002676"
     CDS             complement(2021..2785)
                     /locus_tag="L1V17_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HBN1237381.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMTASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPDYEEVKKKKFGLF"
     gene            complement(2813..3511)
                     /locus_tag="L1V17_002677"
     CDS             complement(2813..3511)
                     /locus_tag="L1V17_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HBN1237382.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAR
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILDEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLNKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            complement(3523..4302)
                     /locus_tag="L1V17_002678"
     CDS             complement(3523..4302)
                     /locus_tag="L1V17_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HBN1237383.1"
                     /translation="MEETISLKEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDALGFPILG
                     TVPEMSAKELNAGIRKKGTAPARPKATNDKTAPSRRSRSRV"
     gene            complement(4318..5262)
                     /locus_tag="L1V17_002679"
     CDS             complement(4318..5262)
                     /locus_tag="L1V17_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBN1237384.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTLQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            complement(5308..6087)
                     /locus_tag="L1V17_002680"
     CDS             complement(5308..6087)
                     /locus_tag="L1V17_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237385.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKNFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKISAAYATKAQTVAQQMGYSNISY"
BASE COUNT         1634 a         1304 c         1125 g         2182 t
ORIGIN      
        1 aattactttc tgaaacttta ggtaatacta ttttttcgtc acacatatat agtgcgggtg
       61 ctagttcaga gcaatctgct ccaatgattt ttccttccat ttcattattg tttaatgctg
      121 ttttaaatgc attcactagt tcacaacgac gtccacaact taatattaaa atattcaatt
      181 tttaatctcc tatctattcg aagcatttgc aaaagtgaca atgtctttag ccaattgttc
      241 atcgtcttgc ggcaggctct tgacaaaatc catcactttt tgtattgagt aacctttgat
      301 gtttcctaca aagattttct cataaactgc ttcatcattt ctttccttat ccaacaatag
      361 ttcttcatat agtttttccc ctggacggat acctgtttca atgatttcga tttcgtcttc
      421 gctatacccg ctcaatcgga tcatgttttt cgctaggtct acaatcttca ctggttcact
      481 catatctaga ataaaaattt cgccaccttt tgctaatgcg ccagattgaa taactaaacg
      541 actagcttca ggaatcgtca taaagtatcg agtcatacga aagtctgtta cagtgattgg
      601 accaccttga gcaatttgtt ctctgaatac tggaatcaca ctaccgcgag aaccaaggac
      661 attcccaaat ctgacagctg agaatttcgt acagccttct tcattcaatc cagtcacaat
      721 catttcagcg attcgttttg ttgaacccat gacatttgga ggattgttag ctttatctgt
      781 cgataccatg acgaagtttt tcacttttgc tgctttagct gcttctgcta cattttttgt
      841 accgaaaata ttgtttttga ctgcttcttt tggattatat tccatcagtg gtacatgttt
      901 atgagcagct gcatggtaga cgatatctgg atgatattgt tccatgatct cattgatttt
      961 ctcgcgatct tggatatctg cgatgatcgg tacgatttct gtaggacaat tttgatgatg
     1021 cgtgcgtaac tcacggtcaa tcaagtagat cgagttctcc ccatgtccta aaagcaatag
     1081 ctttgcagga ttgaattgaa tgatttgccg acagatttct gaaccgatcg atcctcctgc
     1141 gccggtgaca agaatgactt tgtctgtgat ctgatctttg atggattcaa tatccagctt
     1201 tacctcatct cttcccagta aatccactac gtcaattgtt tttaattttg atacgctaat
     1261 tttccctgaa gcaagttctt ctatagaagg catcgtgttg actttcacac gagcggattc
     1321 gactaactcg aagattcgtc gtaatttttt tcttgataag gaagggatag cgatcgttac
     1381 catttgaatg tcatattttt caatcaattc cggaatatct tttaatgcac ctaatacttt
     1441 ttttcctgaa agatacgtat ttcttttatt tggatcatca tctacaaacc cgacaacgtg
     1501 gatatcttga gccgttttgg atccaagaaa gctgttgtat aaaatacgcc cgccttcgcc
     1561 agcaccaaca atcaatgtat ttttagcaga atctgctgat acgtatctca tattttttgt
     1621 ttcgatgtag atacgccaga tcaatcggct accgatgatc aataagagcg aaagcagata
     1681 agcaaagata actaaccgta aactgtatcg ccgattaatg aacagcagta tgaggatact
     1741 tgaggcagca cttgcagata gtgaactaaa aattgcaatg atctctctta aatttgtata
     1801 gcgattgatc cgagtgaaaa ctttgaataa actaccataa aataaataaa aaccaatcga
     1861 caaaccgata gagattaaaa taagatccat tggtatagat acaaacggct tcatgaattt
     1921 agctgctgca atatttgcag caattaataa caagctgtcc acaaaaacca atgtggcaat
     1981 ttttcttctt cttgttaata taaacacttt ttaattcccc ctaaaataaa ccaaacttct
     2041 tcttttttac ctcttcatag tctggataac tgatttcatc cccgttgatc agatcctttg
     2101 caacttgctt catctgtact actttttcct taccaaagtc cttggcaatc tgctcatagc
     2161 actcttttaa gtaaaaggtg cgcttagaga ctccgtgtgc atcagaagca gtcatctgca
     2221 cgagattatg tttgaccatt gttttagctg ttttctgaat atctttgcca aataccccaa
     2281 cataacttgg cgcagtaagt tgggccaaac accccatatc taggaacgga agcaaatgat
     2341 tcgggtcttc gcgaaaatgc gcgttgcgtt ctggatggac gatcactggt gtctttccta
     2401 gttctaacaa ctcaaaaaaa agccgttctg catataacgg cacttccagt gtcggaaatt
     2461 cgatcagaag atatgtatca tctaaatctg taaataaaat ttcatctcgg tggatgtctt
     2521 cgatgagcgt tccggtaata cgtacttctt gtccttccaa taacgtcaaa ggcaactgtc
     2581 ttttctctaa ttcggcttgt aacgaagcga ctagagaaat gacttgtgat ttttcattgc
     2641 tgtattttcc attattgtgg tgtggtgtgc ataaaatatg cgtgatgcct tgctgaatcg
     2701 ctttttcagc cattgcaata cttgcttcta agttttctgc cccgtcatcg attcctggta
     2761 ggatatggca atgtagatcg atcatttctc ttgtctcctc tcttcttatt ccttaatttc
     2821 cgtagtaata accagcatct ttgctatgtt ctgctccgtt gtatacaaca cctaaaactc
     2881 gtgcttgtac catctctagc agttcttttg ctttattcaa tgattcttta cgtgatgtat
     2941 tttcacgtac gaccaataaa gtgccatccg tttttgaaga catgatctgt gcatctgtta
     3001 cggctactac tggtggcata tcgaatatca ccacgtcaaa taactgtctt gcttcgtcta
     3061 ggatctgatc cattcttggc gaacttaaca attctgatgg gttgggtggc ttaggtccac
     3121 taggcaaaat cgacaagttc tcgactggcg ttcgttggat tacatctgct acacttcctg
     3181 atgaactaag tgctgtactt aatcccctgg cattgttcag ctggaatgtc ttatagacga
     3241 cgggtttacg taaatctgca tcgactagta gaactcgttg accggattta gcaaaaacga
     3301 ctgcaatgtt tgctgcagtg gtggattttc cttctccagg acctgatgaa gtcacgacaa
     3361 tcgttttgat ttgctgacca gctgcggagg caaactggat attcgtccgg atcgtacgat
     3421 attgttcggc gattggtgaa gatgggtttg ttaatgtgat caaactgact gcatgagttt
     3481 gtgctgcttt ttgtttctgt gttcgtgcca tttttcttcc tcctagactc ttgagcggct
     3541 tctgcgtgat ggggctgttt tatcgtttgt agcttttggt cgtgcaggag ctgttccttt
     3601 tttacggata ccagcgttca attctttcgc tgacatttct ggaactgttc ctaagattgg
     3661 gaatcctaat gcatccgtca catatttttc atctttcact gtccgatcaa gtaattcgaa
     3721 taagaatgcc agacctacgc ctaccatcat tcctaatact aagccaatca ctagattcaa
     3781 tttattattt ggcgaaacag gtgtcgtatt ggcaactgca cctgaaataa tcgagatttt
     3841 atcgacattc atcacgtctt ttgcgttctc ttggaaaact tgtgaagttg tgttagcgat
     3901 ctgttgagca gtcactgcat tcgtgcttat tgcctggatc gagaacattt gtgaattttg
     3961 tgactgattg acggagatcg catctttgat ttgtccagca gtcattttca cattgtcttc
     4021 tgtttctaaa cgatctttga cttcatttag tactaaatca ctgacgatca tatctttata
     4081 cgtattgatc atttgcaggt tcgtattgac atcattgaca tttgctgtgt ctgattgtgg
     4141 cagtgtcacg atcaattgtg cttgtgaact gtattttggt gtcaagatga aaaatgttac
     4201 gattcctgag atggccaagc cagcaaacat tgagatgatg attgttacca agtgtttgcg
     4261 taatgtttca aaaatttctt tcaagctgat tgtctcttcc attttttctc cactttccta
     4321 tttattctct agattcattt gatcttttaa ttcttttttc acacgatcaa gttcttgatc
     4381 gctgactttt tgataggaga tattatcttg catgaagcct tctccttgca gctgatcttg
     4441 cttgatcgta ccaaatgcct cccgataatc taaagcgatt tttttcattt catcaaagct
     4501 catgtctgtt ttcatattcg actctagagc attcaaaacg gattgatagt tgctgacacc
     4561 gtttaaactc aatacttttt ttgctacacc ttctacgatc tttctttgac gctcttgtct
     4621 accatagtca ccatttggat cttcataacg catacgagaa taagataatg cctgatcccc
     4681 gttcaatgta attttaccga ttggaaagtc atagccatct tgtgagaaag tgaggtcatt
     4741 attgacttcg ataccaccaa ctgcatcaac gagttccttt agccctttca tattgataga
     4801 gacatagtga tcgattggga tgtctacata tttttgtagg gtatccatcg ccatggcagc
     4861 tccgccgaat gcgtaagcgt ggttgatctt gtcttttgtg tcacgaccta cgatgtcgac
     4921 atacgtatct cgaggaatgc tgacgatcgt tgtctgtttg tcttcaggac tgactgtggc
     4981 aaccatcatc gtatctgatc ttccttgatc gacccgacct aaatctccag tatcaatgcc
     5041 catcaataga acagagaaag attcttgttt gtccagatca actggtttcg ttcgttctcc
     5101 ttgggttcgt tccactgatt cgtaagtttt ctcaatagaa tgtgagagat ccagatataa
     5161 ttttgctcct actcctacaa ttgctaatac taatacgata agaactgcta aaataatcag
     5221 aaatattttt ttccctcttg attttcttct tcgtcttgcc atagtttcct ccgtttgcta
     5281 accttgcttg aatcaacgtt ttaactgtca ataacttata ttgctatagc ccatttgctg
     5341 agcaacagtt tgtgcttttg ttgcgtatgc tgcgcttatt ttttcattcc ggatctgctc
     5401 tatttgactg agcgccgtca aatattgatc gtaagtagcg gtggcagtca cttgaccatc
     5461 cttcaacatc gtatcgaata actgatctag ttgcgtgact tgcgcgatct gagtatcagc
     5521 gaatcctaga tattgcataa caaccgtttt ccaaggacta tctttaaaaa agctcatatt
     5581 ttcacgtaca cgagcgacat ctgcacttgt caccttttct ttgatgacga catcgtctac
     5641 agcttgctgc cagtttgata catttttagt aaataaatcg ttgacagctg tctggatctt
     5701 cagttttgat tctgcactat ctaactgtgt cacgattgct ttcttctcat cttggattgc
     5761 aacagcttct ttaggcaatt ctgattcttt gatgtcgtaa tcatctgctg aaagtttgac
     5821 agaggatagc ttatttgaca aacttgtgat tgtttcttct gttatttcag ggtttagaaa
     5881 atttttttct tttgtactat acagcttgtc tacttctttt gataaagaag tcaaggtgtc
     5941 tttttgattg gtgatggcag attctgcata attgatccgt tgctgatgtt gccgctgatt
     6001 attgatatgg taaccaaaca aacagatcgc aatagcacct gcacctaccg ccacagcagt
     6061 caatgacttg acgaatggct tttccataga ttcactccta agtattgatg atagataaat
     6121 taagatataa ttcacataca taaaaatgac agctttttat tttaaaaaac ataattaaat
     6181 taatatattc acagaaatat ttgtaaacaa gttttcccta tataatcata ccacaaacta
     6241 ttttc
//
LOCUS       DAFLWC010000121         6173 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.125, whole genome shotgun sequence.
ACCESSION   DAFLWC010000121 DAFLWC010000000
VERSION     DAFLWC010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.125"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            725..811
                     /locus_tag="L1V17_002681"
     CDS             725..811
                     /locus_tag="L1V17_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBN1237386.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="L1V17_002682"
     CDS             complement(932..1621)
                     /locus_tag="L1V17_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237387.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1866..2780)
                     /locus_tag="L1V17_002683"
     CDS             complement(1866..2780)
                     /locus_tag="L1V17_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBN1237388.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="L1V17_002684"
     CDS             complement(2762..3142)
                     /locus_tag="L1V17_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HBN1237389.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="L1V17_002685"
     CDS             complement(3592..3879)
                     /locus_tag="L1V17_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBN1237390.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="L1V17_002686"
     CDS             complement(3899..4123)
                     /locus_tag="L1V17_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HBN1237391.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4578..4748)
                     /locus_tag="L1V17_002687"
     CDS             complement(4578..4748)
                     /locus_tag="L1V17_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237392.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4763..5296)
                     /locus_tag="L1V17_002688"
     CDS             complement(4763..5296)
                     /locus_tag="L1V17_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBN1237393.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..6159)
                     /locus_tag="L1V17_002689"
     CDS             complement(5317..6159)
                     /locus_tag="L1V17_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBN1237394.1"
                     /translation="MREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEKILSL
                     RFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQF
                     NELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQEL
                     TAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALALADKQ
                     KEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLLSDLD
                     NLFQ"
BASE COUNT         1633 a         1151 c         1042 g         2347 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtgtatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DAFLWC010000122         6131 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.126, whole genome shotgun sequence.
ACCESSION   DAFLWC010000122 DAFLWC010000000
VERSION     DAFLWC010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6131
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.126"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..509
                     /locus_tag="L1V17_002690"
     CDS             <1..509
                     /locus_tag="L1V17_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="HBN1237395.1"
                     /translation="LENIEKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYL
                     KTDIIYITNLEPEEYLTILKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKN
                     IINANLNENEIETALNKIQDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIK
                     WIQKQIAY"
     gene            482..1159
                     /locus_tag="L1V17_002691"
     CDS             482..1159
                     /locus_tag="L1V17_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBN1237396.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            1149..2291
                     /locus_tag="L1V17_002692"
     CDS             1149..2291
                     /locus_tag="L1V17_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBN1237397.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            2304..3281
                     /locus_tag="L1V17_002693"
     CDS             2304..3281
                     /locus_tag="L1V17_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBN1237398.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            3281..4189
                     /locus_tag="L1V17_002694"
     CDS             3281..4189
                     /locus_tag="L1V17_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HBN1237399.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            4190..4942
                     /locus_tag="L1V17_002695"
     CDS             4190..4942
                     /locus_tag="L1V17_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HBN1237400.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            4947..5894
                     /locus_tag="L1V17_002696"
     CDS             4947..5894
                     /locus_tag="L1V17_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HBN1237401.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT         2250 a          770 c         1165 g         1946 t
ORIGIN      
        1 aactagaaaa tatagaaaaa caaattttag ctttgatcaa ttcaatggaa caacaatctc
       61 aaccaattat ttgcatttta cctaatagtg atgctggtag cgaaattatc agaaaaatgt
      121 accagaaata tttaaaaacg gatattattt atattacgaa tttagagccg gaggaatacc
      181 tgactatatt aaaagagtgc aaatttatga tcggaaattc ttcttctggg ataattgaag
      241 ctgcatcatt caaaatacca gtaataaatt taggaaccag acaaaatgga cgagaacaat
      301 ctaaaaatat tataaatgca aatctaaatg aaaatgaaat tgaaactgct ttgaataaaa
      361 tacaagatcc tcagtttata aaaagcttga aaaatgttaa gaacatctac ggtgacggca
      421 acagttctag aagaataaca aaaacattga atcaaatatt gaatgatggg gaagatatta
      481 agtggattca aaaacaaata gcttattaaa atatactagt gatccataca ttattattgg
      541 ggctggcgga cacgcaaaag tcattattga aaccttaaga ttagaaaata agttaatata
      601 tggatttttt gatgataagc aaaataaaat gcaagatctg aaatatcttg ggaaaataaa
      661 cgaattgaat agctgggcgg atagcaaaaa aaaaatctat aaatttattg tagctattgg
      721 tgactgtgta gtaagaaaaa agattataaa aaaattgaat atgccaagtg agcaatatgg
      781 aatagctgtt catccaagtg ctatagtggc aaaagaaatt tcaattggtt atggaactgt
      841 tatttttgcg aatgctgtaa ttaacccaga tgctgtaatt ggagagcatg ctataataaa
      901 cacaggtagc attgttgagc atgattgtag aattaataac tatgttcatt tatctccagg
      961 tgtatgctta gcgggtggag tacatgtagg tgtaggaact caaataggaa ttggttctca
     1021 atgtatccag atgaagaaaa ttggatcttg gtgtatgata ggcgcaggga gcactattgt
     1081 taaggatatt ccctcacatt ccttagctta tggcaatcca gctaaaatta agaaagaagg
     1141 aattaatttt gaattctaga attttattat caagtcctca tatgggagga acagaagaaa
     1201 aatatgttgc taaggctttt aaagataatt ggatagcgcc attaggtgaa aatgtggata
     1261 aatttgaaga aagtattaca aaatatactg gttctaaggg cggagcttct gcgttaagtt
     1321 caggtacagc tgccatacat cttgccttaa gactgcttaa tgttggaaaa aacgatattg
     1381 tctttgctcc ttcatttact tttatagcta cagtaaatcc tattttatat caaggggctg
     1441 taccagtgtt cattgactca gaacctaata catggaatat gagccctgtt gcactagaga
     1501 gcgcattaga agaagctgaa agaaacaacc aattacctaa ggcaatcatc gtagtgaatt
     1561 tatatggtca aatggctgat tatgaacgaa ttttagctat tgcaaaccaa tttaatgttc
     1621 cagtgataga agatgcagcg gaatcgttag gttctactta taagggaatt tcgtcaggct
     1681 tatttgggac aattgggatc tattcattta acggtaataa gatcatcaca acctcaggtg
     1741 gaggagctct agtgtctagt gataaaaaat atgttgagca ttcaagattt ttagcaacac
     1801 aagcaagaga tcaagcaccg tattatcaac atagcgaaat aggttataat taccgtctaa
     1861 gcaatatttc tgccggtatc ggacgtggac aaatggaagt attgaatgat agagtagcta
     1921 aacgaagaga aattttcaat cgatataagg aagctttttc tggaattgat agaattgaaa
     1981 tgatgccaga agtggatggc atggtgccaa atcgttggtt gtctacttta acgatcaatg
     2041 attataattc tattgatcaa gtagttaacg taataaataa actaaatgaa aaaaacattg
     2101 aaacaagagc tttgtggaaa ccactacatt tgcaaccagt atttcaaggg gtaaaaatgt
     2161 attaccatga taataatctt agtgtgtcag aaaagttatt taatagcggc ttatgcttac
     2221 cttctggaag taatatgaca gatagtgaac aagaatttgt tattgatgag tttaaaaaaa
     2281 tattcaagta ggtgtgatat tttatgaaca taggaattat tggtttaggt tccatgggga
     2341 aaagaagact tagactcatt caagaacact ttaatgatat tttactatgt ggtgttgata
     2401 ctaatgaggc gagacgaaag gaagttgaaa aggaatttgg aataccaact tataatagtc
     2461 taacagaggc aaaaaatttg tttgaaataa attcagtttt tgtttgtaca tcccctataa
     2521 cccatgaatt tattataaaa gaggctttaa atttagattg taatatcttt acggaaatca
     2581 atttattaaa tgaatattat gatgaaataa tcgaagtagc taaaaagaaa gatagattac
     2641 tttatctatc ttctacattt ttgaagagaa aagaaattca atatattaag tctaaagtga
     2701 cgcataataa aaaaatttct tatcaatacc atgtaggaca gtatttaccc gactggcatc
     2761 cttgggaaga ttatcgcaat ttttttgttt caaacaaaaa aactaatggg tgtagagaaa
     2821 tattcgctat tgaattacct tggattatag atacatttgg gaaagttaaa tcgtttactg
     2881 taatgaccca gaaattatcc aatcttgata ttgattattc ggacagtttc actcttatta
     2941 ttgagcatga aactggtata gttggaactt taagtgtaga tgttgtttca agagtagcta
     3001 aaagaaattt aactataatt ggtgaaaaga ttttaataga atgggaaggt aacccggatt
     3061 ctctattttc atggaatgaa gaaacttcta gtatgacaga tattcaattg tacgatgagg
     3121 ttatgcatga taataattat tcacatacta ttattgaaga tgcatattta gaggagatta
     3181 aagaattttt cacgcttttg gaaaagaaaa tggaacccca atatactttt gaaaaagata
     3241 agtatattat taacttaatt aacgacattg aggtaaatta atgatgaaag taattttttt
     3301 tgggttaggg tcaattggaa agagacatct aaaaaatcta ataagctatg gaaaaaagaa
     3361 ttctattaat tttgatataa cagcttatag tagcagtgga aaaaaagagt ttgaagaaat
     3421 aacgtatatt caaaatagag acgatttgga tacacattat gatatagctt ttattacaaa
     3481 tccgactttt aagcatctgg aaacactaaa tgtaattgtt gaaaaagttg attacatatt
     3541 tttagaaaaa cctgcttttt ctgagagtat tgatcttact caatataatt atgattacaa
     3601 aaatatttat gttgctgctc cactgaggta taaaaatatc atggaagttg ttcgtaatag
     3661 tattcaaagt aaaaaagtat attctgtaag agctatttgt tctacttatc ttcctgattg
     3721 gagaaaaggt actgattata gaaataatta ttctgccttt aaatctatgg ggggaggagt
     3781 agaattagac tgtatacatg aattggatta tattataaac ctatttggtt tccctaaatc
     3841 agtaaaaaaa cagtttggta aatattcgaa tcttgaaatt aacagtaatg atttagcaac
     3901 atatatattg agatacgatg ataaaattat agaaattcat ttagattatt ttggaagagt
     3961 tcctacaaga aaatttcaat tgtttacttt agatgaatgt atcaatgttg acttattaaa
     4021 taataaaata agttttgaag aaaacattgt taaagaaatg cctgaatctg ctaatgatat
     4081 gtatgagaag gagttgaaat atttctttga aaacgtagta acaggcaaag aaaactggaa
     4141 tgatttatat catgcaaacg aagtattgaa aatagctgag gagaaataaa tggaaatttt
     4201 atttactatt tgtggtagag ctgggtctaa ggggtttaaa aataaaaatt tgaaatattt
     4261 ggcaggaaag cccctagtcc atttcgcttt agcaatgata gatatctatc aacaaaaaca
     4321 tcctgaacat aattgcacga cttgtttgaa tacggacagt aatgagttag tagaattgac
     4381 gactaagtta aatccgtctg tgaaaattgt agaacgtaaa cctgaattag ctacagatac
     4441 tgtagggaaa attgaagtga tacgtgattc attcttacaa ctagaaagag aagataatat
     4501 atttgattta attatagatt tagatttgac ttcaccttta cgtgaagttt ctaatcttga
     4561 agaattaata gatgaacatc taaaaaattt agataaagac gtctactttt cagttgtttc
     4621 tgcaagacgt aatccctatt ttaatatggt aaaaagaatt gaaaatgaag ttactatagt
     4681 taataaatca agatacacat ctaggcaaca gacacctgaa gtttttgaaa tgaatgcctc
     4741 aatgtattct tttaaacctg aatttctaaa aaaaagtaat tatatttttg atgggcaatg
     4801 tgggataata aaaatgagag attatctaat tttagatatt gatagtgaag aagattttaa
     4861 atggttagaa tttttgtttc ctaaattttt agaagattct tcggagcttc aagatatcta
     4921 taattattta tatcggaggt aaaaggatga gctgttatct tatcaccggt ggggctggct
     4981 tcattggttc taccttagcc aatcatttag gagaagaaca tgtggtaatc gtcgtcgatg
     5041 acttatcaat gggaaaagta gaaaatcttg atatgacgaa aaatatcact tttattgagg
     5101 gagatgtcgc tgagaaatcc ttgatggaag agatcatgaa agctaataaa tttgattata
     5161 tctttcattt agcagcagtt gctagtgtgg cagattcagt tgcccgacca gtagaaacac
     5221 atcgtgtgaa ttttgaaagt gtattaatga ttttagaatt gatccgcaag tatcaacctg
     5281 atttaaaacg gatcgtgttt agttcttcag cggctgttta tggggatgaa ccgactttac
     5341 caaaaaaaga agagtccgtg attcgcccat tgacgcctta tgcggttgat aaattcgctg
     5401 cagaacaata tgtgctagat tattgtcatt tatatgatgt acccggtagc gcagttcgtt
     5461 ttttcaatgt ctatggtcca aatcaaaatc cgaattctcc atacagtggt gtgatttcta
     5521 ttctcgtaga tcgctataag aaacaaatcg taggagaagc aacttcattt acattatttg
     5581 gtgatggaag ccagtctaga gactttgttt atatagatga tgtaatccaa gcattacttt
     5641 tagttgcgaa tgaggaagct gcactgggga aacaattcaa tgttggaacg ggtaaagcaa
     5701 ccacactttt ggaattgatt catgcaatca atgaaattct cggtgtagaa ttgacacttg
     5761 aatacaaaga agagcgttcg ggtgatatcc atgactctct agcagatatt actaagatcc
     5821 agtcaattgg ctatcaaccg aaatatggta ttttaagtgg aatgactaat tatttgaaaa
     5881 ctgaaatcaa ttaaaacata ctaagataag attagagggt aaattcaggc tctttgtcaa
     5941 taaggactga tgagttttgt aaaatcaaat ctgggataga agggctcttt gtcaaatgat
     6001 gttggtaaag agaaatctta gaataatttg gacagaacag aaagaagaaa acctctttct
     6061 gttctgttta tttggttaaa aatgttttgc catgacgaat cataattcgt agtttgaaat
     6121 tgtaaaagtt g
//
LOCUS       DAFLWC010000123         6011 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.127, whole genome shotgun sequence.
ACCESSION   DAFLWC010000123 DAFLWC010000000
VERSION     DAFLWC010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6011
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.127"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(50..352)
                     /locus_tag="L1V17_002697"
     CDS             complement(50..352)
                     /locus_tag="L1V17_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237402.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKDVYFLFDIVTDVLDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(572..938)
                     /gene="ssrA"
                     /locus_tag="L1V17_002698"
     tmRNA           complement(572..938)
                     /gene="ssrA"
                     /locus_tag="L1V17_002698"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1109..1882)
                     /locus_tag="L1V17_002699"
     CDS             complement(1109..1882)
                     /locus_tag="L1V17_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1237403.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            2026..2376
                     /locus_tag="L1V17_002700"
     CDS             2026..2376
                     /locus_tag="L1V17_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBN1237404.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2357..3073
                     /locus_tag="L1V17_002701"
     CDS             2357..3073
                     /locus_tag="L1V17_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1237405.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            3073..4521
                     /locus_tag="L1V17_002702"
     CDS             3073..4521
                     /locus_tag="L1V17_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBN1237406.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4592..5101)
                     /locus_tag="L1V17_002703"
     CDS             complement(4592..5101)
                     /locus_tag="L1V17_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237407.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(5091..5816)
                     /locus_tag="L1V17_002704"
     CDS             complement(5091..5816)
                     /locus_tag="L1V17_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237408.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
BASE COUNT         2047 a         1044 c         1170 g         1750 t
ORIGIN      
        1 aagtatggtg ataaaatccg ttccgggcta cctttttagg tagcctactt taatctttgt
       61 atctttctgg atcaacgaaa gtatacttta tatagtcata acgccgatga tcgcttcgag
      121 cgtctagcac atcagtcacg atatcaaaca aaaaatatac gtctttcttc attctagttt
      181 tcgcagcagg gattttaaag tagttcttat tagaatagta gagattaatt aataagctat
      241 cttcgattgc taaaaagaaa acttctgaat cccacacctt ataaaaatct ttgacaaatc
      301 tattcgaagg atcaaattta aaccataatt gtgtttttcc ttccatcaac ataatgttca
      361 cctcaaaaag agtatacgaa ctaatgttct ttttgtaaag taggaatatc attgataata
      421 tggatggaac atatatatta aaaagtgttc tttttgaatg ctattttgaa tgccattttc
      481 attcatttaa cgaaaatctg cgaaaataaa aaatgctcaa acccttataa aataaggatt
      541 taagcatcta gcgaaatctg ctgaaatctc acaatggaga cggcgggagt cgaacccgcg
      601 tccaaacaca tcgccactta aaaatctacg ttcatagtca actcatttaa ggattcactt
      661 tacagcttgc cgagtgacag gcattctgta tcgctagtct gatgttctct ttttcaactt
      721 acagacggaa agttgaaacg tatcccacta aagttaggac ccttactcga gcacatgggc
      781 gatgccgaga ggatctacgc taactgtttt taggcagcta aagcgtaaga gttgttttcg
      841 tttttagcag ttatatttaa ctgtaacgtt tttacgtaga cgtaacctac gaaacgcaat
      901 tcaagctcga ctgtgcctgt cgaatccgta acgtccccgt tagctaacaa gggttacgtg
      961 tatttttcat acaaaattag tatagcatat attgggataa attcaataaa aaagcgaatc
     1021 atatcccatt atttatataa taactgcccc tttcttaaga aaaaataagc gattttctta
     1081 agaaaagagg tagcttcaaa aaaagatctt aaatcagatc aaaatacttc aatgcgtgga
     1141 caattccgcc ttctgtattt ttctttgtga taaaggtaga aagttctttt aatccgtcat
     1201 aggcgttgcc catagcgatt ttgttgtcgc aagcttccaa caaggcaaaa tcattcggac
     1261 catcgccaaa tccaaaagta ggaacttttt ccagctgaag ttctttttgc agacgtttga
     1321 cacctgcccc ttttgagatt cctttcttca ctgtatcgat cgagtaagga ccattccgat
     1381 aaaaagttag ctcaggaaaa tgttcgtgat agtattcgtc acctgattga gataagatca
     1441 gcaacatatt tactgtgttt tctttaaagc ctaaaggatc aatttccgga acatctgaat
     1501 gaatgaagtc gtaagcattg atcattgttt ggctatgacc ggtacaccag attttctgat
     1561 cgttatagta agaaagttca tgaccgttca actgtacatg atcatacatt ttttgacatt
     1621 cttctgaaga aaatgtttga gaatagattt cttcgccgtc tactcgaatg aaagaaccat
     1681 tcatggtgac cgcagaagta atgcccgcat cttccatgat agagtggatt tctgcttctg
     1741 tacgtcctgt agcgatgacg gggagaacat tgttttcttt taatgcgttc atagcttttg
     1801 ccacttcggg tgtgattttt gatttcgcat ctagtaatgt tccatcaaga tcaaagaaag
     1861 tgattgcacg ataatttgac acaaataaaa ctcctttttt attggaataa gtttatctta
     1921 acaaagaatg aacaaaagac aaacctttcg tgaagaattc ctgaacatat tggttcagtc
     1981 aacaatttag agtatactat aagaagagaa tttaggaggg aaagaatgat ttttttcagt
     2041 attggtatct tattcttaat aattggcagt ctttttcgga ttctgccctc aaaaggaaat
     2101 ctgccttttt atgggtatca ttcgcctctt gccgcaaaaa cagacgctca ttggcggctg
     2161 gctcaaaaga caagcggaaa ctggtttttt cttatgggct tactgatggc attgatcggc
     2221 tattatttaa agacatctgg gcatacgaat tattttctga ttgaaatgct tctgctagta
     2281 tttccaatta tgcctatttt tattatgaca gaaaagaaat tacagaaata tgacctggaa
     2341 actggaggga acgataatga atattttaat gattgaagat aatcaatctg tttctgaaat
     2401 gatgcagatg tttttcttaa atgaaggttg ggaagcaact ttcaagtatg atggaaaaga
     2461 agggctcgat gcctttttag aaaacccaca acattgggat atgattacac tagacctgaa
     2521 tttgcccaca ctggacggta tgctagtagg aagagagatc cgcaaagttt caagtactgt
     2581 gccgattatc atgctgacag ctagagattc tgaaagcgat caggtgatcg gcttagagat
     2641 gggggcagat gattatgtca caaaaccttt cagtcctctg acgcttattg ctcgaatgaa
     2701 agctttgcat cgccgtagtg agttggcaga agcaagagaa gaagcagtag tttcagatga
     2761 tcattttgat atcgagacta gtcatttcaa gatgaatacg aaaacacgag aagcgtatct
     2821 ggacaaccgg ccaattgaag gactgacgcc taaagagttc gatctattgt ttactttagc
     2881 aaaaaaacca cgtcaagtat tctctcggga gcagttgctt gaattagtct gggattatca
     2941 gtactttggt gatgaacgga cagtggacgc ccatatcaag aaattacgac aaaaaatcga
     3001 aaaggtcgga ccacaagtca tccaaactgt ttggggagtc ggctacaaat tcgatgattc
     3061 tggtgttgcc taatgcgtta tttgtatcag caactcttag ctttctgcgg aatggtcgcg
     3121 ttgatcttat tgatcgttgg agtttctttt acacaactga caaaacaaac gattgaagaa
     3181 aacaattacc agcaactgtt tggatatgct gaatcagttg aaaagacaac gcaaacctat
     3241 gccgatacgc tcccgcagtt tagtcaagat caggcgtttc aaaatgcatt gctgctgaca
     3301 gagcaagtac tgacagaaca aaatgtgaac tttatattta tcgataaaaa cgaacgtgtc
     3361 atttatccga ctaatacagc tttactgaat tttaccttaa cagctgatca atggaaaaat
     3421 ctgaggaatg gacgtcaaga aaaattcaca tcgaataaaa atattttagg acaagcacag
     3481 gcgacctctt acgcacttgt gccatttaat ttgaatcatg aattctatgg agcacttgta
     3541 gttagtcaac ctgcgcgaaa tatcgataac agcgttcgtc caattacact gaacctgttc
     3601 aaaggattta ttttttccag tatcgttgca gttattgcca gctatgcttt tgcagcattc
     3661 caagttaagc gtatcaatcg gttaaggaat gcgacgaaag aagtgacgaa tggtaatttt
     3721 gatgtacagc tccccgtaca tgacaaagat gaatttgatg agttagcaga tgatttcaat
     3781 aaaatgacga attcattgaa agaatctcaa gcagaaattg aagaacaaga aaatcgtcga
     3841 agacaattta tggcagatgc ttctcacgag atgagaacac ctcttacgac aatcaacgga
     3901 cttctggaag ggttagaata caatgcaatc cctgaaaatc agcgagaaaa cgcgattaaa
     3961 ttgatgaaaa atgaaacaga gcgtctgatc cgtttggtga atgaaaactt ggattatgaa
     4021 aaaatccgta cgaatcaaat cagtatggtc attaaaaaat tcaatggaac agaaacattg
     4081 aaaaatattg ttgcacagtt agaagctaaa gcagaagcag caggagatac attgacattg
     4141 aaagccgttg atgatattga tgtttacgct gattatgacc gatttgtcca aatcatggtc
     4201 aatattattc aaaacgcgat acagtttact gaaaacggcc aaatcacgat tactttagaa
     4261 aaaggctatc ttgaaacgat catcacgatt gaagatacgg gaattggaat gtctgaacaa
     4321 caaatgaaaa gtatctggga tcgttattat aaagtagatc cttcaagaaa aaatacaaaa
     4381 tatggtgaat caggattagg tttaccaatc gtgcagcaac ttgtacgctt gcataaagga
     4441 aaattagaag tagaaagcga actaggaaaa ggaacaaaat tcgctgttcg tttgcctgac
     4501 gtagaaatca aaaaagagta aaaaacaagc ggtataaaag atcatgaatc gatcttctat
     4561 accgcttgtt ttttactata aaatgattga tttagcccgc gggctctaaa cgatcaatat
     4621 aaggactttg agcaatagta gcatcatgag taaagagtaa gataccttga ttttcttcat
     4681 gagctaaata agaaagcaag tggagtagct cttggatctc caatacacta agttcatcaa
     4741 atgtatcttc aataacaata ttgtttcgct tggaaagcaa ggcatgaagt aattgcagct
     4801 ttactttttc aaaagacgtc aactcagctg ccgcacaatt aagcaaggaa ggagagatat
     4861 caagtttttc ttgataggcc aaacgatctt gtttgatttc tttttccggt acatccaaca
     4921 ggacatggtc tttaagattc agataaggaa acatcggcca atttttttgg atgatcgcaa
     4981 aattatccag ttttgcaaca agaacctctt ttttcaagtg ctccaatatt ttatgctgtt
     5041 tttcgagagg acacaaaata acggtcaagt gttcagcatg aatcaaatat tcaggtttca
     5101 ttacgtccag gcctcctact ttgcaaatga tggataaaaa aagtgaaagg gaatagacta
     5161 agaatgagac agcatccact gagcccaata agagtttggg caaatccctt aagtatatct
     5221 gtgaaaaaaa gatcattttg gaaatcgatg gtaaaaaaag tctgttgatc catcggaatt
     5281 gtaagtccgc ttaccgaagt caagatatca cggatatctg gcagttcagt agtctttaag
     5341 acaagaaaat tgatcctttg aagaagcgct tcataaactg actggaagct tacgatccac
     5401 aataaaacca agatacaaca aagaaagaga ggaaagaaca gctgccagaa aataaaaagg
     5461 aataatttgg ttttagaaag accagtcagg tgccaattga tcaattcctg cttgttttgc
     5521 ctgactgaat agtaaaagaa aaagataaaa aggaaggcaa atagaaaaaa taaactgaat
     5581 atgcctttta tataaaatcg gctagctaat tctaaagccg gaagaagctc tgtagatgca
     5641 gaagcgccaa taaatgaaag ccgatcttgg acttgattgg ctaaagccga ttgcaaatgg
     5701 taaagagtca ggcatgctat caataaaaaa gcagaaaagc ttgaaaataa acaatagagt
     5761 attgtctgct ttttgtaata aattaatcga gcagtagcat agcggattat tttcatactt
     5821 ttcacctcta taaaaagtat agaaaatgaa tatgaataaa gtatgaaatt cctttagtga
     5881 aatcacgaat taaaaccaga aaatattttg taaaaagcaa gaggttgtga agaagctgcc
     5941 ctattctatt accgtagatg caagcttttg aacactgttt attcgaaaag aggagcagcg
     6001 acaataattt t
//
LOCUS       DAFLWC010000124         5972 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.128, whole genome shotgun sequence.
ACCESSION   DAFLWC010000124 DAFLWC010000000
VERSION     DAFLWC010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5972
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.128"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..450)
                     /locus_tag="L1V17_002705"
     CDS             complement(<1..450)
                     /locus_tag="L1V17_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBN1237409.1"
                     /translation="MKYKEMFVPSLIQLAVEVKNKEEAFLIAAQQLEKMGYVNENYLN
                     GLIAREREFPTGLITKYLNIALPHSECEYVEKPFVFVMQLKNPIYFYQMGDNQEMTVE
                     NLFFLGIKEPKEQVGLLQAFMNLFMDETFVENYKKQETPQNIYELITN"
     gene            674..1465
                     /locus_tag="L1V17_002706"
     CDS             674..1465
                     /locus_tag="L1V17_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBN1237410.1"
                     /translation="MLKKERQEQIITLLEKDFYLTNSEIANKLGVSEMTIRRDVTELA
                     KKNKVKKLYGGVERKEPYNRELSTQEKIDTNVAEKKYIGQVMNSMIPDNSTIYVGAGT
                     TILYALPFIQKKNLFVITNSLIAFNYLKNHTSYRILLTGGEFSPITEEFIGEVAERSF
                     ESLNVDISFAATNGIFDNNVTTAQFIEGNIQNAALNAAKIKCIVADYSKLNKSDVYTF
                     RKLTDFDYLITDNHLSEQDFNHYSKYLTILKEPKNDTDNHDEPIH"
     gene            1431..2384
                     /locus_tag="L1V17_002707"
     CDS             1431..2384
                     /locus_tag="L1V17_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HBN1237411.1"
                     /translation="MILTITMNPSIDSIYFTKHFELGTMTRFDSPVRYVGGKGINCGR
                     ASALLGSSVILTGFLGGYFGSMIQDMLKNENLFDLHFLPIAEESRGAVTIMHDDETQT
                     ELVEAGPEIADTTIKKLMNDIKLISKNNYLSVITINGSVNNPDPFLYAKLLQYIKEQI
                     DPSTYILMDISGQHLREVLASKYKPMFIKPNIHEFSDIIHQKITQKSDIKHHLKTNPL
                     FKDIDVIMISCGSYGAVVKVKEEFWNVEIPKIPIINTTGSGDATVGGFAHSLEQNYPL
                     KECVRYAMACGMSNAQQSEVGKVIPADVKNLAKSIKITEMK"
     gene            complement(2782..3756)
                     /locus_tag="L1V17_002708"
     CDS             complement(2782..3756)
                     /locus_tag="L1V17_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBN1237412.1"
                     /translation="MNKELNITQEWDKVFPKSNQVNHRKVSFPNRFGITLVADLYEPK
                     EVSEKKLPAIAVSGPFGAVKEQSSGLYAQTMAERGFLTIAFDPSFTGESGGVPRYVAS
                     PDINTEDFQAAVDFLSVQKNVNPERIGIIGICGWGGMALNAAAIDTRVKATVVSTMYD
                     MTRVTANGYFDVMDENARYEMREELNAQRIIDFKQGDYARAGGVVDPLPEDAPQFVKD
                     YHAYYKTDRGYHVRSLNSNDGWNRTSGLSLMNAKLLHYIPEIRHAVLVIHGEKAHSRY
                     FGEDAFKELKGDNKELMIIPGASHTDLYDQTDIIPFEKMATFFEENLV"
     gene            3871..4305
                     /locus_tag="L1V17_002709"
     CDS             3871..4305
                     /locus_tag="L1V17_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBN1237413.1"
                     /translation="MYSIGQVSEMFGLPVSTLRYYDKEGLFPDIQRVSGIRKFSENEL
                     EALRVIDCLKKSGLEIKDIKQFMEWSKEGSKTFEVRKELFEKQKEVVEKEIAKLERVL
                     AMLNYKSWYYEEAIKAGNEEAVLTMIPDDLPQHVKEAYVHSH"
     gene            complement(4430..5452)
                     /locus_tag="L1V17_002710"
     CDS             complement(4430..5452)
                     /locus_tag="L1V17_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HBN1237414.1"
                     /translation="MKKIGFLSFGHWMEQGSLVKSAQDAYLQSIDLAVEAEKIGVDGA
                     FFRVHHFAPQIGSPFPLLAAIGAKTSKIEIGTGLIDMRYENPYYMAENAGLTDIITQG
                     RVQLGVGRGSPEQVLDGWKYFGYDYSEEEIKEVTRERTLEFLELLEGKPFEEPNPQPM
                     FPQGSGKLRIEPYSEGLRQRIWWGAGSQQTAIWAAQHGMNLQSSTLVNYESHEPFHIQ
                     QANQLRAYKEAWKQAGHDFEPRTLVTRSIQPITTDLDRRLFGQDGSPQQDAVGYLAYH
                     RNPTIFGKTFAGEPDQLIKELAEDEAIKEADTVLVTIPNTLGVEYNMHLLETIVKDIA
                     PELGWR"
     gene            5844..>5972
                     /locus_tag="L1V17_002711"
     CDS             5844..>5972
                     /locus_tag="L1V17_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (thioredoxin)"
                     /protein_id="HBN1237415.1"
                     /translation="MKKIYFLCTGNSCRSQIAEGYARKYLSPSMFEIRSAGIETHGL"
BASE COUNT         1876 a         1126 c         1029 g         1941 t
ORIGIN      
        1 atttgtaata agttcgtata tgttttgcgg tgtttcttgt ttcttgtaat tttccacgaa
       61 tgtttcatcc atgaataaat tcataaacgc ttgaagtaat cctacttgtt cttttggttc
      121 tttgattcct aaaaaaaata gattttctac agtcatttcc tgattatccc ccatttgata
      181 aaaataaatt gggttcttca gctgcataac aaaaacaaat ggcttttcga catattcaca
      241 ttccgaatgt ggcagcgcga tatttaaata cttagtaatc aatccagtag gaaattctct
      301 ttctcttgca atcagtccat tcaaataatt ctcattgacg taccccattt tttctaattg
      361 ttgtgcagcg attaaaaaag cttcttcttt attttttact tctaccgcta attgaatcaa
      421 actaggaacg aacatctctt tatatttcat tccaacctcc tcctttttga ttaagtttgt
      481 taatttattg ttctactaaa ttcatctttg ttttacaaga acattatatt tctgttagtt
      541 tgttttgtca acgctttcaa aagaaattta ttttgttaaa tttgatctac ttgaaaataa
      601 aatcgtttat ctatataatt aagaagaaca aagtcgaaca aaaattgact tttatgttaa
      661 aggagtaatt catatgctga aaaaagaaag acaagaacaa atcattacat tattagagaa
      721 agatttttat ttaactaatt cagaaatcgc taacaaatta ggcgtatcag aaatgaccat
      781 acgccgagat gtcactgaat tagcaaaaaa aaataaagta aaaaagctat atggtggcgt
      841 tgaacgaaag gaaccttata atcgagaact atcgactcaa gaaaagattg atacgaatgt
      901 agccgaaaaa aaatatattg gtcaagtcat gaacagtatg attcccgata attctactat
      961 ttatgtcggt gctggaacaa cgatcctata tgcacttcct ttcattcaaa agaaaaatct
     1021 atttgtaatt acaaacagtt tgattgcttt caactattta aagaatcata caagttatcg
     1081 gattttactt actggtggcg aattttctcc tattacagaa gagttcattg gggaagttgc
     1141 agaaagatct tttgaaagtt tgaatgtcga tatctctttc gctgcaacaa acggcatatt
     1201 tgataacaat gtgacaaccg ctcaatttat tgagggaaat attcagaacg cagcgctcaa
     1261 tgcagcaaaa atcaaatgca ttgttgcaga ttattcaaaa ttaaataaat cagacgtcta
     1321 tacttttaga aaattaaccg attttgatta tctaataacc gataatcatt tatcagaaca
     1381 ggatttcaat cattattcaa aatacttaac aatattaaag gagcccaaaa atgatactga
     1441 caatcacgat gaacccatcc attgattcca tttattttac aaaacacttt gaattaggta
     1501 cgatgacacg ctttgattct ccggtacgct atgtaggcgg caagggaatc aattgcggac
     1561 gagcttctgc tctactaggt tcatcagtta ttttaacagg gtttttgggc ggttattttg
     1621 gcagtatgat tcaagatatg ctgaaaaatg aaaatttgtt tgatttgcat tttttaccta
     1681 ttgcagaaga atcaagaggt gccgtcacga tcatgcatga tgatgaaacg cagacagagc
     1741 tagtggaagc tggtcctgaa atagcagata ctactatcaa aaaattaatg aatgatatca
     1801 aactaatcag taaaaataat tacctttcag tcattacaat aaatggttct gttaacaatc
     1861 cagatccctt tttgtatgct aaattattac aatatatcaa agaacaaata gatccttcca
     1921 cctatatatt aatggatata tctggacaac atctccgtga agtcttagca agtaagtata
     1981 aaccgatgtt catcaaacct aatatccatg agttttcaga tatcatccat caaaaaatta
     2041 ctcaaaaaag cgacataaaa caccatctaa aaacaaatcc actatttaaa gatatcgatg
     2101 ttatcatgat ttcttgcggc tcgtatggtg cagtagtcaa agtaaaagaa gaattttgga
     2161 atgttgagat ccctaagatt cctatcatta atacaacagg ctctggggat gccactgttg
     2221 gaggttttgc tcattcatta gaacagaatt atcctttaaa agaatgtgta aggtacgcaa
     2281 tggcttgcgg catgtcgaat gcacagcaat cagaagtcgg gaaagttatt ccagctgatg
     2341 taaaaaattt agcaaaaagc attaaaatca cagaaatgaa ataaatagta caaagtaaat
     2401 aattgtttat atgaaatgag acacaaagag actgtgacaa aaaacgtgtg taccgacccc
     2461 caaaagttag attttttggt ctaacttttg ggagtcgata cattgtcaca gtcctttttt
     2521 cgaataaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
     2581 gagaagctat tttttgaaat tgctccttgt gactcagagt taaacggcag gctcacgacc
     2641 tcttggtata aacggtgttc aaaagcttgc atctacgcta atgagtccaa ccaagtcaaa
     2701 aatgaggagc ttttttggct gtccttatta cttgatgcag ggcagttttt tcataatctc
     2761 ttttagatta aatccttttg gttacacaag gttctcttca aagaatgttg ccattttttc
     2821 aaatggaatg atgtctgtct ggtcgtatag atctgtatgg gatgctcctg gaatgatcat
     2881 gagttccttg ttgtcacctt ttagttcttt gaaagcgtcc tccccaaagt aacgtgaatg
     2941 agctttttcc ccgtgaatga ctaagactgc atgacggatt tctggaatat aatgcaatag
     3001 ttttgcattc ataagtgaca accctgatgt cctattccaa ccatcattgg agtttaaaga
     3061 acggacatga tatccgcggt ctgttttata atacgcatga tagtctttga caaattgagg
     3121 agcatcttca ggcaacggat caaccacacc tccagcacgt gcgtagtccc cttgtttgaa
     3181 atcaatgatg cgttgtgcat ttaattcttc acgcatttca tatcgggcat tttcatccat
     3241 aacatcgaag tagccatttg ctgttactcg agtcatgtca tacattgtgg aaacaactgt
     3301 tgctttgacc cgcgtatcga tagctgctgc attcaatgcc atacctcccc atccacaaat
     3361 accaatgatt ccgattctct cagggtttac atttttttgt acagataaaa agtctactgc
     3421 cgcttggaaa tcttccgtat tgatatcagg cgaagcaaca tatcgaggta ctcctccgct
     3481 ttctcctgta aacgatggat caaacgcaat cgttaaaaag cctctttcag ccatcgtctg
     3541 cgcatataga ccagacgatt gttccttcac tgcaccaaat ggcccgctca cagcgattgc
     3601 cggcaatttc ttttcactta cttcttttgg ttcatataaa tcagcgacta atgtgatacc
     3661 aaaacgattc gggaagctca cctttcgatg attgacttga ttgctttttg gaaatacttt
     3721 gtcccattct tgtgtgatgt ttaattcttt attcatattc tagactctcc tttgatcaaa
     3781 attgacattt gtttttgaat gtattattat gataaaactt aaacttgact ttaggtcaag
     3841 gtaaaaattt tattttagga ggattttttt atgtattcca ttggacaagt gtctgaaatg
     3901 tttggattgc ctgtttctac tttacgttat tacgacaaag agggattatt tcctgatatc
     3961 cagcgtgttt ctggtattag aaaattttca gagaatgagt tagaggcttt aagagtcatt
     4021 gactgtttga aaaaatctgg tttagaaata aaagacatta agcaattcat ggaatggagc
     4081 aaagaaggca gtaagacatt tgaggttcgt aaagaactat ttgaaaaaca aaaagaagta
     4141 gtagaaaaag aaatagcaaa attagaaaga gtactcgcta tgctaaacta caaaagctgg
     4201 tactatgaag aagcaataaa agccggcaat gaagaagccg tattgacaat gattcctgat
     4261 gatttacccc aacatgtaaa agaagcttat gtacattctc attgaacaaa cggataactc
     4321 actctccttc tctatgaact tcatgaaaac atgaataaac acctctaact gattgttaga
     4381 agtgtttatt ttttcactca agtatcctgc acttacaaaa atatcctttt taccgccatc
     4441 ctaattctgg agcgatatct tttacgattg tttcaagcaa gtgcatgtta tattctaccc
     4501 ccaaagtatt aggaatcgtg acaagtactg tgtctgcttc tttgattgct tcatcttcag
     4561 ctagctcctt gattaattga tcaggttcac cagcaaaagt ttttccaaaa atcgttgggt
     4621 ttcggtgata agcaagatag ccgacagcat cttgttgcgg actaccgtct tgtccaaata
     4681 agcgtcgatc caaatcagtg gtgattggct gaatcgagcg agtaactaat gttcttggtt
     4741 caaaatcatg acctgcttgc ttccacgctt ctttatacgc acgtaattgg tttgcttgtt
     4801 ggatatggaa tggctcgtgg gattcgtaat tgactaatgt agatgattgc agattcattc
     4861 catgttgtgc tgcccagatt gccgtttgct gcgaaccagc tccccaccag attctttgtc
     4921 gtaatccttc tgaataaggt tctatccgta attttcctga tccttgtggg aacattggtt
     4981 gaggatttgg ttcttcaaat ggttttcctt caagtaattc caagaattca agggtgcgtt
     5041 cccgtgttac ctctttgatt tcttcttcac tgtaatcata accaaagtat ttccagccat
     5101 ctagaacttg ttcaggtgaa ccacgcccca ctcctagttg cactcttcct tgcgtgatga
     5161 tatctgtcaa tccggcattt tctgccatat aataagggtt ttcatatcgc atatcaataa
     5221 gtcctgtacc gatttcaatc ttacttgtct ttgcgccgat tgccgctagc aaaggaaacg
     5281 gcgacccaat ctgaggggca aaatgatgta cgcggaaaaa cgctccgtcc actccgattt
     5341 tttctgcttc caccgctaaa tcaatcgatt gcaaataagc atcttgagct gatttcacaa
     5401 gcgatccttg ctccatccaa tgtccaaagc ttaaaaagcc gatttttttc aaggtaatga
     5461 cctcctttaa acctacaaaa atggaaggtt ttttattttt aatatgaact gattctacta
     5521 ctttttttct taaaagacga ataattgttc tcgcctcaca atcaagaaat gtatcggctt
     5581 actacacccc tactttcttc atcatctgcc gtgtcttaat ctcttttaac agtctgttac
     5641 atcgttgatt tttgactcaa aatgattgtt tctaacatgt atttatggta aaaaagacaa
     5701 gattagttct ttgtacacat cgatttatac gctgaacaaa aagaaatata taaactaaga
     5761 aacccattgt tttttcgctc catcacatag agtttacttt agataaacag tgacatttac
     5821 taatccataa cggaggaaat caaatgaaaa aaatctattt cttatgtacg ggcaattcat
     5881 gccgcagtca aatagcagaa ggctacgcgc gtaaatactt gtctccttca atgtttgaga
     5941 taagaagtgc ggggatcgag acacatggct tg
//
LOCUS       DAFLWC010000125         5677 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.129, whole genome shotgun sequence.
ACCESSION   DAFLWC010000125 DAFLWC010000000
VERSION     DAFLWC010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5677
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.129"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..717
                     /locus_tag="L1V17_002712"
     CDS             <1..717
                     /locus_tag="L1V17_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HBN1237416.1"
                     /translation="LSTLSRNKKYIENETDSVVLVSSEKVIDICENKILTSAFFEQNG
                     FKTPEILNSSEITKFPVFIKPLNGSSSVNTFIVNNEKELLFFSEYIDNPLIQEYILGE
                     EYTIDVCLNFDSTPVSIVPRKRIATRGGEILKGQIIKDRELIETTKKMLEKLNAIGHI
                     TIQCIKNEKGIFYLEINARYGGGAPISIKSGANSPEYIIKMIDSKKNLRYRENYLDKM
                     IALRYDQAIYLDEKGNVYND"
     gene            689..1405
                     /locus_tag="L1V17_002713"
     CDS             689..1405
                     /locus_tag="L1V17_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HBN1237417.1"
                     /translation="MKKEMYIMIKAVIFDLDDTLVSEYDYVKSGYKCVARRLAVQKIF
                     PATFDEIYRVLLDLFAEDSKNVFNRLYDYFEIPYSKKEIKELVNVYREHKPDINFLEN
                     ADTLLTELRSRGYKLGIITDGYAITQRNKLDALKVDYLVDYICITDELGRELWKPHPI
                     SYLLLLEKFNLKAQECIYIGDNELKDFITAKSIGMQTIKIERVNGIYRESSLKFKRFY
                     QADKKIRSLWEIKNFLGVIS"
     gene            1402..2520
                     /locus_tag="L1V17_002714"
     CDS             1402..2520
                     /locus_tag="L1V17_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBN1237418.1"
                     /translation="MKSKRILLASPHMSEEGYEKEYVKEAFDTNWVAPLGANVNGFEK
                     ELAEYVGASHAAALSSGTAAIHLALKAAGVGKDDIVICQSLTFSATANPILYQGAIPV
                     FVDSDYETWNMKPEHLRTALEKYPNTKAVLVVHLYGLSANLDEITKICKEYDVTLIED
                     AAESLGTTYKGKYTGTFGDYGIYSFNGNKIITTSGGGMLVSNDKEKVEKVRFWATQSR
                     EKARHYQHNEIGYNYRMSNIVAGIGRGQLKVLNERIEKKRYIHSFYKKELSKLSNIQF
                     MPENNWNEPNYWLSVITIKGINANHLIDELDKNNIEARPVWKPMHLQPVFKNYDYIGD
                     DVAETLFDLGVCLPSDTKMTDEDLKYVVSTIKRVINDA"
     gene            2510..3130
                     /locus_tag="L1V17_002715"
     CDS             2510..3130
                     /locus_tag="L1V17_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBN1237419.1"
                     /translation="MMRKKTFYQLFGKRILDILLSGIALIVLSPIILIVGFLVRIKLG
                     SPIIFKQERPGKSEKIFSMYKFRTMTDERDHNGEYLPDEIRLTKFGKMLRATSLDELP
                     ELWNILKGDMSIVGPRPLLVEYLPLYSEKQRKRHNVRPGLTGLAQVNGRNAISWEEKF
                     DLDVYYVDKISFFNDLIIIIQTCKKVIKKENINTINNNIPEKFKGS"
     gene            3257..4426
                     /locus_tag="L1V17_002716"
     CDS             3257..4426
                     /locus_tag="L1V17_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBN1237420.1"
                     /translation="MCRVLNILFQYEKIIKKYKEKRVMAKYYNKKILIMANNDDGLYR
                     FRGMLIKNLVDQGNEVIVSLPKGKNIPKLIELGCQIIETPIDRRGINPKTDFKLFFNY
                     CNILKKIKPDMVIAYTIKPNIYGGLACRLRKVSYALNITGLGTAFQKKGVLKSLIVFL
                     YRLAAKKSKVIFFENFENMKTFQTLQIAKQSKYKLLNGAGVDVEHFSYLEYPKDEQVH
                     FLFIGRIMKEKGVDELFEAMKNLYSEEKNCVLDVLGYFEEDYGIKIEKYEKEGWLKYH
                     GYQSDIRPFVERAHCFVLPSWHEGMANTNLESAASGRPIITSDIPGCKEAVIESKSGY
                     LCERKNSCSLYNSMNKFLKLSYEQRINMGKMGRNYMIKKFNKKKVVDETIKSLFS"
     gene            4433..4828
                     /locus_tag="L1V17_002717"
     CDS             4433..4828
                     /locus_tag="L1V17_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1237421.1"
                     /translation="MFCKVCDRKEGFCGFRIDIKELAKVSDIFLFTTLQEGMPRSMME
                     AMASGLPCIASKIRGNVDLLVEGKGGYLVPAKDAELVAECLRELINNKSLRKYMGNEN
                     LSRIKEFEVSIVKKRIKEIYEEVIGESVK"
     gene            4825..>5677
                     /locus_tag="L1V17_002718"
     CDS             4825..>5677
                     /locus_tag="L1V17_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBN1237422.1"
                     /translation="MKNPMFSIIVPIYCVEKYLKDCLDSIRNQTFKNFEAILVDDGSP
                     DECPEICDYYSQIDGRLKVIHKKNGGIIDARKTGVTSAMGEYIVFLDGDDWLANTYLE
                     KYAEVITKYNPDIICSGYFASRSNKIRKRELSCSFGYYDKDKIINLIYPKLIEDEHGE
                     YFRPQLWAKAFRTTLYKEQQQVSGQVSVGEDHACTKPCIYHANSIYMMEKCLYYYRIN
                     ENSITKKPQPYYWEGPKAIGEHFEKQIDMNKYDFQDQVYRNVTHNLFNVAVSQFNKQD
                     KYLNIKKD"
BASE COUNT         2211 a          667 c         1064 g         1735 t
ORIGIN      
        1 ttatcaacat tatcaagaaa taaaaaatat attgaaaatg aaacagactc agttgtatta
       61 gtttcttcag aaaaagtcat cgacatttgt gagaacaaaa ttttaacttc tgcttttttt
      121 gaacaaaatg gttttaaaac tcctgaaatt ttaaactctt ctgaaattac aaaatttcct
      181 gtatttataa aacctctgaa tggtagttca tctgttaaca catttattgt aaataatgaa
      241 aaagaattgt tgttttttag tgaatatata gataatcctc ttattcaaga gtatatttta
      301 ggtgaagaat atactataga tgtttgctta aactttgatt cgacaccagt aagtattgtt
      361 cctagaaaaa gaatagcaac tagaggtggg gaaatactga agggtcagat tattaaagat
      421 agagaactaa ttgagactac gaaaaagatg ttggaaaaat taaatgcaat cggacatatt
      481 actattcaat gtataaaaaa cgaaaaggga atattttatt tagaaataaa tgcaagatac
      541 ggtggaggag cccccattag cattaaatca ggagctaatt cccctgaata tattataaag
      601 atgatagatt caaaaaaaaa tttgagatac agagaaaatt atttagataa aatgatagca
      661 ctgagatatg atcaagcgat ttatttagat gaaaaaggaa atgtatataa tgattaaagc
      721 ggtgatcttt gatttagatg acactcttgt gtctgaatat gattatgtaa aaagtggata
      781 caaatgtgta gctagaagat tagcagtgca aaaaattttc ccggctactt ttgacgaaat
      841 atatagagtc cttttagatc tttttgctga agatagtaaa aatgtattta atcgtctata
      901 tgactatttt gaaattcctt atagtaaaaa agaaattaaa gaactggtaa atgtatatcg
      961 agaacacaaa ccagacataa attttttaga aaatgcagat actttattaa cggaattaag
     1021 aagtagagga tacaagctgg ggattattac agatgggtat gctataaccc aacgaaacaa
     1081 attggatgct ttgaaagtag actatttggt agattatatt tgtattactg acgaattagg
     1141 ccgtgaattg tggaaaccac accctatctc atatctttta ttgttagaaa agtttaattt
     1201 aaaggcacaa gagtgtatat atattggcga taatgagttg aaagatttta taactgccaa
     1261 atcaatagga atgcaaacaa ttaaaataga aagagtaaat ggtatttaca gagaaagcag
     1321 tttgaagttc aaaagatttt accaagctga taaaaaaata cgttcgttat gggagataaa
     1381 aaattttttg ggagtgattt catgaaaagt aaaagaattc tattagcttc tccacatatg
     1441 agtgaagaag gatatgaaaa agagtatgta aaagaagcat ttgatacaaa ttgggttgct
     1501 cctttaggtg cgaatgtgaa tggatttgag aaagaattag cagaatacgt gggagctagt
     1561 catgctgccg cattatcttc tggaacagca gctatacatt tagctttgaa agcggctggg
     1621 gtcggtaaag atgacatagt gatttgtcag tccttgacgt tctcagctac tgctaatcca
     1681 attctctatc aaggagctat acctgtattt gttgatagtg attacgaaac ttggaatatg
     1741 aaacctgaac atttgcgaac agcactagaa aaatatccta acacaaaggc tgtattagta
     1801 gtacatttgt acggtttatc agctaattta gacgaaatta ctaaaatatg caaagaatac
     1861 gatgttactc taattgaaga tgctgcagaa tcattaggaa caacatataa aggaaaatat
     1921 actggtacat ttggcgacta tggaatttat tcttttaatg gaaataagat aatcacaact
     1981 tcaggtggcg gaatgcttgt atccaatgac aaagaaaagg tggaaaaagt gagattttgg
     2041 gctacgcaat ctcgtgagaa ggcacgccat tatcaacaca atgaaattgg ctataattat
     2101 cgaatgagca atatcgttgc tggtatcggt cgaggacaat tgaaagtatt aaatgaaaga
     2161 attgagaaaa aacgatatat tcatagtttt tataaaaaag aattgtctaa attgtcaaat
     2221 atacaattca tgccagaaaa taattggaat gaaccgaatt attggttaag tgtcataaca
     2281 ataaagggaa taaatgcgaa tcatcttatt gatgagttag acaaaaataa tatagaagcc
     2341 cgcccagtat ggaaacctat gcatttacaa cctgttttta aaaattatga ttatattggc
     2401 gatgatgtag cagaaacttt atttgactta ggagtatgtt taccatcaga tacaaagatg
     2461 acagatgaag atttaaaata tgtagtatct acgattaaaa gagtgatcaa tgatgcgtaa
     2521 aaaaactttc tatcagcttt ttgggaaaag aattttagat atcctattgt caggaattgc
     2581 tctcatcgtt ttatcgccga taatcttaat tgtaggtttt ttagtaagaa ttaaacttgg
     2641 ttctccaatt atcttcaaac aagaacgacc aggaaaaagt gaaaaaattt tttccatgta
     2701 taaatttcgt acaatgactg acgaaagaga ccacaatgga gaatatttac ctgatgaaat
     2761 tcgactaact aaatttggga aaatgcttag agcaacaagt ctggatgagc tacccgaact
     2821 ttggaatatt ttgaaaggtg atatgtcgat cgtaggacct cgtccattat tagtggagta
     2881 tttgccacta tatagtgaga agcaacggaa aagacacaac gtaagaccag gattaactgg
     2941 actggctcag gtcaatggaa gaaatgctat tagttgggaa gaaaagtttg atttagatgt
     3001 ttattatgtt gataaaatta gtttctttaa tgatcttatt attataattc agacatgtaa
     3061 aaaagtaatc aagaaagaga atattaatac aatcaataac aatatcccag aaaaatttaa
     3121 agggagttaa atacagcagc ttaatgcaag ttttgtgact tgcattatat ttaggtataa
     3181 atcaaagcga gtatattaga attatataac atatgttaaa aaaacgtata gctaataaaa
     3241 gtatgatttt aaaaatttgt gtagagtttt aaatatactg tttcaatacg agaaaattat
     3301 aaaaaagtat aaggaaaaga gagttatggc aaagtattat aataaaaaaa ttcttataat
     3361 ggcaaacaac gatgatggtc tttaccgttt tcgaggaatg ctcataaaaa acttagtaga
     3421 tcaaggtaat gaagttattg tatctcttcc aaagggcaag aatattccta aattaattga
     3481 acttggatgt caaattattg aaactccaat agatagaaga ggaattaatc caaaaactga
     3541 ctttaaacta ttttttaact attgtaatat tttgaaaaaa ataaagccag atatggtcat
     3601 tgcttatact atcaaaccaa atatatacgg tggattggca tgtcggttaa gaaaggtttc
     3661 ttatgcatta aatataaccg gattaggaac ggcatttcaa aaaaaggggg ttttgaaaag
     3721 tcttattgta tttttgtata gattagcagc taaaaaatct aaggtcatat ttttcgaaaa
     3781 ttttgaaaat atgaaaacat ttcagacttt acaaattgct aaacaaagta aatacaagct
     3841 attaaacggt gcaggagtag atgtagaaca ctttagttat ttagaatatc ctaaagatga
     3901 gcaagttcat tttttattta ttggaagaat tatgaaagag aaaggtgtag atgaactttt
     3961 tgaagcaatg aaaaacttat atagtgaaga gaaaaattgt gtacttgatg tccttgggta
     4021 ttttgaagaa gattacggca taaaaattga aaaatacgaa aaagagggat ggttaaaata
     4081 tcatggatat caatctgata ttcgtccctt tgtagaaaga gcacattgct ttgttttgcc
     4141 tagttggcac gaaggaatgg caaatactaa ccttgaatca gcagcatcag ggagaccaat
     4201 tattacaagt gatatcccag ggtgtaaaga agcagttatt gaatcgaagt ctggttattt
     4261 atgtgaaaga aaaaatagtt gtagtctcta taattcgatg aataaatttc taaaattatc
     4321 atatgagcag cgcattaaca tgggaaaaat ggggagaaat tatatgatta aaaaatttaa
     4381 taagaagaaa gttgtcgatg aaacaattaa atcattattt agttaaaaag atatgttttg
     4441 caaagtatgt gatagaaaag agggattctg tggcttcaga atagatatca aagaattggc
     4501 aaaagtttct gatatttttt tatttactac attacaagaa ggaatgccaa gatctatgat
     4561 ggaagctatg gcaagtggat tgccatgtat agcaagtaaa atccgaggta atgtagacct
     4621 tttagtggaa ggaaaaggtg gatatcttgt tccagctaaa gatgcagaat tagtagcaga
     4681 gtgtttgaga gaactaatca ataataaatc tcttagaaag tatatgggaa atgagaacct
     4741 ttccagaatt aaagaattcg aggttagtat cgtaaaaaaa agaatcaaag aaatatatga
     4801 agaagttata ggtgagagtg taaaatgaaa aatccaatgt tttcaataat agtacctatc
     4861 tattgcgttg aaaaatattt gaaagattgc ttagattcaa taagaaatca gacatttaaa
     4921 aattttgaag caatactagt tgatgacggt agtcctgacg aatgcccaga aatatgtgac
     4981 tattattccc aaatagatgg acgtttaaaa gtaattcata agaaaaacgg tggaataata
     5041 gatgcacgga aaacaggagt cactagtgct atgggagagt atatagtttt tctagatggt
     5101 gatgattggc ttgcaaatac ttatttagaa aaatatgcgg aagtaattac taagtacaat
     5161 ccagatataa tatgtagtgg gtattttgca tcacgttcca acaaaattag aaaaagagaa
     5221 ttgtcttgct cgtttggata ttatgacaaa gataaaatta taaatttgat ttatcctaaa
     5281 ttaattgagg atgaacatgg agagtatttt agaccacaat tatgggcaaa agcttttaga
     5341 actactctgt acaaggaaca acaacaagta tctgggcaag ttagtgttgg tgaagatcat
     5401 gcatgtacaa aaccatgtat ttaccatgca aattcgatat atatgatgga aaaatgttta
     5461 tattattaca gaataaacga aaattctata acaaaaaaac cacaaccata ttattgggaa
     5521 ggaccaaagg ctattggaga gcattttgaa aagcagattg atatgaataa gtatgatttt
     5581 caagatcaag tatatagaaa tgttacacac aatttattta atgttgctgt ttcacaattt
     5641 aataaacagg acaaatattt aaatataaaa aaagata
//
LOCUS       DAFLWC010000126         5675 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.130, whole genome shotgun sequence.
ACCESSION   DAFLWC010000126 DAFLWC010000000
VERSION     DAFLWC010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5675
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.130"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            72..1040
                     /locus_tag="L1V17_002719"
     CDS             72..1040
                     /locus_tag="L1V17_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBN1237423.1"
                     /translation="MANEIVKYHHELNTIPLRKFTSVEMNLFFSIISRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKADIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGIA
                     NFSKEDFHELLDIPKSYRESDINKKIIKPIRQELTAIFKGLTIQKRYGKGRGKPVIGY
                     QFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKEPTSLQEKIKEQKRKLELL
                     QQLAELERKQNTPSKKINKQIADNNSDITPEFKENLLDNLQNLFKE"
     gene            1050..1538
                     /locus_tag="L1V17_002720"
     CDS             1050..1538
                     /locus_tag="L1V17_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBN1237424.1"
                     /translation="MTDKTIKELADILGVSKDKVKYQLRKLPSNFTYKKGNITYLKKE
                     AVTTITKVLSGNESGNLPSELPDSLPTDYLLKEIETKNNHIEEKDRQIEKLQIALETQ
                     QKLLDQQQQLTLQANQQIKKLHEQLQLTYAEESSEKEPLSVTEETQKGQNKEKKWWQF
                     WQ"
     gene            1834..2115
                     /locus_tag="L1V17_002721"
     CDS             1834..2115
                     /locus_tag="L1V17_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237425.1"
                     /translation="MDILVRNIDPKVISEIDRRCQELTTKTGKKWSRNAYLKVLIEND
                     FDQALRHYKKDQFDLLLEKFIDIQAKNTETLNDYVHTNNQLIETLIGGI"
     gene            2117..2533
                     /locus_tag="L1V17_002722"
     CDS             2117..2533
                     /locus_tag="L1V17_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237426.1"
                     /translation="MRKTSVQKHVTLYPSHIDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPNTNTTTTSNQAKLNAMGKEISIMSEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSRNFDPTNFLKR"
     gene            3147..4301
                     /locus_tag="L1V17_002723"
     CDS             3147..4301
                     /locus_tag="L1V17_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HBN1237427.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYIYTVKKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSDNG
                     QIKLLWKSPLSTEKNGVSSLTEKNDLISVNIKNKIKNFSKKQNFPAVKRVKSVSSGDN
                     FIMINWRIAETQTSFPWCAAYVEAAILCNKTDVRATSARAIMHYTYPNLNNSQIESKS
                     LNQDQIIKYANYCGVYPKKIARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHALAL
                     FGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            4295..4717
                     /locus_tag="L1V17_002724"
     CDS             4295..4717
                     /locus_tag="L1V17_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237428.1"
                     /translation="MVNKLIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
BASE COUNT         2149 a          971 c          919 g         1636 t
ORIGIN      
        1 attagggggt tgacccccat tagaaagctc tttataattt tgttaagtag ttaatcttga
       61 aggaggattt tatggcaaat gaaattgtga aataccacca tgaattaaat acgattcctt
      121 tacgcaaatt tacgtcagta gaaatgaatt tattcttctc tataatatct agaatgcgtg
      181 atgtaggcga taaaaaagta caatttacat tcgaacaatt aaaagattta agcaattata
      241 aagcaactgc aaatgttcga ttcatagatg atttagaaac aacgtatgac aaattaatgg
      301 atttacgttt tggtagaaga agtgctgacg gtttgcaacg tgaacgattt gttttattta
      361 atcaatttaa aatcgatgga aaagctgata ttccttttgc tgaaatacaa gtccatgaga
      421 aagccttacc cttacttaat aatcttgaag aatgggttcg atattctctc caacaattca
      481 atgaattaga aagcagttat tccaaaacca tgtttagatt attaaaacaa tacagaacca
      541 aaggaattgc caatttttca aaagaagact ttcatgaatt acttgatatc cctaaaagtt
      601 atagagaaag tgatataaat aaaaaaatta taaagcctat tcgccaagaa ctaaccgcaa
      661 tcttcaaagg tttgacaatc caaaagagat acggaaaagg acggggaaag cctgtcattg
      721 gctatcaatt tacatttaaa cctgagataa aaaaatcaga cgactttaac aaacatgctc
      781 caaccaaaga agaacaaaat aaagctttgg aactagctaa tcaacaggtt caatctgaaa
      841 aagaacctac ttcattacaa gaaaaaatca aagaacaaaa acgaaaatta gaacttttac
      901 aacagttagc agaattagaa agaaaacaaa ataccccaag taagaaaatt aacaaacaaa
      961 tagcagataa caattccgat attaccccag aatttaaaga aaacttacta gataatctcc
     1021 aaaacttatt taaagaataa ggggttttta tgacagataa aactatcaaa gaattagcag
     1081 atattctagg tgtttcaaaa gataaagtga agtatcaact gaggaaatta cctagtaatt
     1141 ttacctacaa aaaaggaaat attacctacc tgaaaaaaga agcagtaaca acaattacaa
     1201 aggttttatc aggtaatgaa tcgggtaact tacctagtga attacccgat tcattaccta
     1261 ccgattacct actcaaggag attgaaacta agaataatca tattgaagaa aaagataggc
     1321 aaattgaaaa acttcaaata gctttagaaa cgcagcaaaa attactcgac cagcaacaac
     1381 aactcaccct acaagccaat caacaaatca aaaaacttca cgaacaactc cagctaacct
     1441 atgcagaaga atcttcagaa aaagaacccc tttctgttac tgaagaaact caaaaaggac
     1501 aaaacaagga gaaaaaatgg tggcaattct ggcaataacc caacaatttt tattcataaa
     1561 aattgttggg ttactttctt tttttgcttt tacaagcata gcgacatgat ctcacgtcgc
     1621 tattttttaa agagcataag gaaacgcggt atcactttct tacgaaaggt gctaggtagg
     1681 ctgtgcctac cacgtttcta agaaaaaaat ttgctatcac tttttcgtca ttgtggatag
     1741 cttatgtata gtgtttcggc aaaaaacagc tatacaaata ctatatttgt atgatataca
     1801 taaattatac acaaatgcga aaggaattct tctatggaca ttttagttcg gaatattgat
     1861 ccaaaagtta tttcagaaat agatagacgt tgccaagaac tcacaacaaa aactggcaaa
     1921 aaatggagcc gtaatgcgta cctaaaagtt ctaatcgaaa acgattttga ccaggcactt
     1981 aggcattaca aaaaagatca attcgattta ttactcgaaa aatttatcga tatacaagca
     2041 aaaaatactg aaacattgaa cgactatgtt catacaaaca accaactcat tgaaacactt
     2101 atcggaggaa tataacatga gaaaaacttc tgttcaaaaa cacgttaccc tttatcccag
     2161 tcacattgac gttttagatt ccatcatcga aaaaaatcca gatatcaata actactcgga
     2221 agccattcgt tttctatgta tgagttatga acctaatact aatacgacaa ctaccagcaa
     2281 ccaagcaaaa ctaaatgcga tgggaaaaga aatttctatt atgtccgaaa tcattgcaga
     2341 atttgctgat ttatatctaa aagatactgg tgttcttatc ggtacaaatt ctaaagtata
     2401 tcaagaagtg aaagaaaaaa ttgaaaatca actcaatccc tcccgacgaa atcaacccaa
     2461 aaatcgtcaa aaagaaacca atcaaacatt cacttctaga aattttgacc caacaaactt
     2521 tctaaaaaga tgaaaaagaa accgaaaatt ttttctattt ctcagtttct tttttagggg
     2581 gcagtcttcc agcaagattt gcaagttacc ggtaacttgc acaaaaaaag aaaaatccgc
     2641 ttgtgcgaat ccttcttttt gcattttggg gcgctgcccc aatctccaaa tatcggttat
     2701 ttaatagcgt ggtaactcaa aaaaatagaa cgtactctga aataaaaaaa gactgctcta
     2761 acgagcagcc aataaaaaat aatgagcgtt tattcttgaa aaagcagcgc gcttatgaag
     2821 cgctgccaaa aatttaccat attttatgaa aaataacaag tttctaaaaa ggaatcggtt
     2881 aagattcaca aagaatcgta aacagacaat agcggaaaat caagcttccg aacgtacctt
     2941 ttagctagac caatgaaaaa tcacaaagtg agcggctgga tcggttggta gaggggctac
     3001 ttggcatagt acacattatg ttaactaacg ctataaataa cgattatgtt cccaaaacaa
     3061 tattttatga actataacaa aaatttgtta tcgcatattg tatattttaa ttataggtgt
     3121 ataccactta aatttaacac aaaggcgtga ttattttgaa acccaaaaag aaaatttatc
     3181 taggtctcct cttttccttg atgattggaa tttttagtat aggaattaca aatacctatg
     3241 cttcagaaaa ttctaatttc aatatcaact cccaaccaat tgaagaacaa gcaattaatt
     3301 ttgcgaaaac tgattttgaa cactccataa cttcaattct tttaatggaa aataacaccg
     3361 aaactgatat taactatact cttggttcgc catttaaaat gctcgatgga gaaaatacgg
     3421 caaatagttc tattttcttt ccagtatttt cagacgctga taatacgatt aaatatattt
     3481 ataccgtcaa aaaaaataca aatggagaat attcaggaag tatttcacaa tttttagcaa
     3541 aagaacttca aaatctagta gatagtaata taacagatac aaccttattt tttcaagata
     3601 atagcattta ttattccgat aatggacaaa ttaaactact ttggaaatca cctttaagta
     3661 cagaaaaaaa tggtgtttct tcccttacag aaaaaaatga tcttatatcc gtaaatataa
     3721 aaaataaaat taaaaatttt tctaaaaaac aaaattttcc tgcggttaaa cgtgtaaaaa
     3781 gtgtctcctc cggagataac tttattatga ttaattggcg tatagcagaa acccaaacaa
     3841 gttttccgtg gtgcgctgct tacgtagaag ctgctatctt atgtaacaaa acagatgtac
     3901 gtgctacttc agctagagcc attatgcatt atacctatcc taatttaaac aacagtcaaa
     3961 ttgaatcaaa aagtcttaat caagatcaaa taataaaata tgcaaattac tgtggtgttt
     4021 atcctaaaaa aatagcacga atactaaacc tttcagaggt ccaaacacaa ctaagaaaag
     4081 gaaatgccat ttatatggga actgctggtt atggaaatta tagtaacagc cgtcatgcac
     4141 ttgcattatt tgggtgggtc aatcaaggtg gttatcaaac ttactatgtg tggaatcctt
     4201 ggtataacta cccaactgta ataagtgcaa atgcaggacc agttacaatt cctgtacctg
     4261 gaggtggttt tacttgggac aataccatta caaattggta aataaactca ttgctttagt
     4321 tatgggtcta gtgttagttc ttttcttaac tagttgttca aaaaaacaag aaatacaaaa
     4381 gactgatctg attccttttc taggaacttg gcaaactaaa gatcattcag aacgtctagt
     4441 aatcactaat ttaaatactt caaaaaatat agaacaatat accatcttag taaaagagaa
     4501 caatcataaa attcaaatca ttgataaaaa tttaaatata aatgaacaag ttttcattta
     4561 caaagcaaca aataatttac taacactgcg ctcgaataaa aaacaattag attacacttt
     4621 tagtttggat tctccaaaaa agctcgtatt tattttgaca acgaatgatg ggacagaagg
     4681 gacagctaaa ccaattgaat tttttaaagc tgattgatga atagttgttt gatattacaa
     4741 aacaataatt tcaccgaagg tgaaacaagc gaaactttac aaaaagtggc tagcatttgc
     4801 tagccttttt tgtattgtgg agcgtgggtt ttgaggggga ttcaaggggg agcttgcgcc
     4861 cctttgacaa gcggttattt gcaccaaata cgtaggtatt tggctagcaa atatagagct
     4921 tgccaagccc tttagtgtgt tttgtagaaa gggaccttat agtcactttc acattacaaa
     4981 cgatacgtcc ataggacgta tcaaaagggt gggacttatg agcaaattaa agcaaaattt
     5041 ggctagcaat ccttctaaaa aatacaccta ttgatcagag tcaaaataaa tcagttttcg
     5101 agtgagcgaa tccaaatttg caactctgaa gctttgcaaa tgagtgtgcc ggcttccgta
     5161 aaagtctagg taacattagt cgatatatac atagggctct aatttgcgtt ttaaggcgtt
     5221 ttaaacgttc tggtatgtaa ttataccaaa gcgactttaa aacgccttaa aacgaatttt
     5281 agaggttctg tagaacgttt tagggttgtt agggcttgcc ctgaccgcct gtaaggcgct
     5341 ttaaaaacaa gataagggat tttatctaga cttgtcttaa aacgccgtag atgagcgctc
     5401 agagcttcta aaaggactcc ttacgaactg tttttaagca aaggagcctt taggcgactg
     5461 cgcagtttaa tgtgagagcg tagcgatcac acctttaaag cgaccgtagg gagcagattc
     5521 ccagtttagg aaatttcgcg aacctgtttg gagaaaaaaa gtaggaaaat tttaggcggg
     5581 aaattttgcc cccctctttt ataatctctt ttataacctc tttttaaacc tctttaccgt
     5641 cggctgtatc cttactctcc caaggtgtgc agaat
//
LOCUS       DAFLWC010000127         5368 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.132, whole genome shotgun sequence.
ACCESSION   DAFLWC010000127 DAFLWC010000000
VERSION     DAFLWC010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5368
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.132"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(8..283)
                     /locus_tag="L1V17_002725"
     CDS             complement(8..283)
                     /locus_tag="L1V17_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HBN1237429.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(255..1208)
                     /locus_tag="L1V17_002726"
     CDS             complement(255..1208)
                     /locus_tag="L1V17_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBN1237430.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            1820..3313
                     /locus_tag="L1V17_002727"
     CDS             1820..3313
                     /locus_tag="L1V17_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HBN1237431.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            3448..3744
                     /locus_tag="L1V17_002728"
     CDS             3448..3744
                     /locus_tag="L1V17_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBN1237432.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            3845..4696
                     /locus_tag="L1V17_002729"
     CDS             3845..4696
                     /locus_tag="L1V17_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237433.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            4717..5000
                     /locus_tag="L1V17_002730"
                     /pseudo
     CDS             4717..5000
                     /locus_tag="L1V17_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345737.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1838 a          830 c         1016 g         1684 t
ORIGIN      
        1 ctatatttta atcttttgat cgtctattat atataatccg ttcctcgtcg tttaaagtat
       61 caacataggc gtccattgca agtttgacta tttcatacat aggaatatct tttgcataac
      121 taagatcccg aatggttttt agtacgggag gatctacttg aactggtttt ctttctttcg
      181 cagtgtactt tcgttcccct aactcgacat taatatcatc tttaattgaa atatcttcag
      241 caccaatttt cttcttatct ttgttcgttg gtaataatgc catttagttt aatctccttt
      301 ccaagaggta ggatatgatt ggccattgag tcagcatatt taggtgtata atcaaatcct
      361 tcaatatcac catgttgttc atagtattca attctttctt ctaattctgt aaagatgtct
      421 gcaaaaatag cccaccatct tcgatctaca taatcattta attggatacc attctcacca
      481 tacatttcta accgatccga gcctttaaca atgcttttaa aaatgtttga ttcaccatac
      541 ttatcaattg ttttttgata gtttgcgtgt tgagaggaac gtcgcactga gaaaagaaca
      601 ggcaaaattc caatgatttg aagatgagac tcttcaaaat tcgtgacaat cggaactaaa
      661 actttattaa taaaatcttc tgttccttcc attgcgtacc gttttaattc ttgcattgca
      721 ataatataat ctgcagcagt taagaatgca cgaaccacat tatctgttga tggtgggcag
      781 tcgataaaga tataatcgaa attttttctc aattcttcta aaggtttaat gaaggccaat
      841 gatctcttac gacgatcagg atatttttcg gacaagtatt cattaagttc ttcagatcca
      901 ggagagccag ccataatata taaatgtgga cttacttgag taatacctga aacccagtcc
      961 ccttttttga ttgctgcaga catggatcga tcaaagctag taatttgata cgttgatcca
     1021 atgttggaag tagtatttct ttgttggtca taatcaatta gcaacacgtc tttttcaaaa
     1081 agttgactag aaacaatcgc taataaatca ttgtctgtag tcttaccaat gccgcctttt
     1141 ctacctgtaa gcattacaac ttttcctagt ttatctgatg ttttaaatgc agtccgtaag
     1201 ttttccatag ttccctccaa tttcctatac taaatatatt tagtatactt catatactta
     1261 atatattcga tatatctaat atactccaaa ttgataagaa ttcagacttt ataaggaata
     1321 tagtggatat actaaatata tttgctatat tcagtatatc agatatattc aaaatgtcaa
     1381 aatatatttg tgcgttttgc gttgacaatt tagagtgaaa agaggtaaac ttaattctat
     1441 agaaaccaca gataattcac tatttacaaa gtagcaaaag cagtggtact ctttaaacag
     1501 aaaaattaca taaaaaaaag agacggaaat aattgatttt agcagaatca attatttctg
     1561 aatcacatgg ttaggacatg tgttcacgct cgtctcaaga atatgtaagt agctaccaac
     1621 tacttatatt aaaagttgat cggatacctt ttccgattgc ctttattcta ccaaaaaaag
     1681 gcgagcaact caacagaaga acgtttattt agtgtactta aattaaatat tcttaaacac
     1741 tgaagagaga acacatacta tggctgagat taaagctaaa ctgtgttctc tttttgtttg
     1801 agaaaggacg ttacaatcga tgttgagcga aatttattca gctattctta aaaacggctt
     1861 acgtacatac aaatatcgaa acagcaccat gaaacctgca ggtcatattg attccagtag
     1921 gagtggtgct atctttgcgt accgtagcaa gcaattaatg aatgttgggc gtggtatggt
     1981 cattacttcg gaagaagcta ttttagagaa cgaaaagaaa ctaacgcatt ggacacctaa
     2041 tacctatcgc tttggtactt atgcggatga ttatcgaaca gtggttaaag gtcattctga
     2101 gaaaaactta agtcaaatca acacatttgt agttgatatc gattcaaaag agaaccatca
     2161 aggcgaaatt attttagcct gtttagatca agtgggctac atgccaacgc taattttaga
     2221 atcagatcat ggttatcaag tttattttgt actaaagaca ccaggctatg tcacaaagaa
     2281 aagcaatttc aaggtgatcg atgtagcaaa aaaaatttca aaaacaattc gtctacagtt
     2341 ggctgaaaaa ttgtccggag tggatctagg atgtaaccac ttcggaattg ctcgattccc
     2401 acaagaaaat aatattgttt ttaaagaaat gaactatcag tattcttttg ctgactggat
     2461 tcaatggtcg atgaagcttg aatcagatca aaaaacaaaa gaagatcgag aacgaaaact
     2521 aattgtcttt cctgagaaaa aagaaattcg tcaagtagat gaaccgtggt tcgatatgtt
     2581 acttcataaa gcaaacatcg tcggcggaga aggacgtctt ggtcgaaata atgtgatttt
     2641 cacgctttct ttagcttatt actcttcagg ttatgcattg gatacttgcg aatacaatat
     2701 gttcacattc aacgaacggt tacaggaacc gctatctgaa gcagaattag taaagattgt
     2761 acgtagtgct tattctggta attatcaagc agcaagcaga gaattcatta ttgaattgtg
     2821 ccagcaatgg gtttcaccaa ccttaaaaaa taatgatctg ttcattcaac gacgtggctg
     2881 gtggaaattt aaaaagccac gagatcaaag aaaatatagt cataaaaatg aatggaaaga
     2941 agatctattg gcttatctaa gcgaaaaaag tcttgctagt gagccttatt tgaacctgtc
     3001 aaaaaaagaa ttggcttcac aactaacgat gcccaagcga acacttgata agatcttaaa
     3061 tgagttacga gaggagaata aagtcttcta caaggtaaca cgaggaagaa atggcggaat
     3121 gatcattgct tcagtcaaaa cgttgttcgc gagggttatt caactaagta aagaaaagag
     3181 actagattat tcaacaagga tcacagaggt atttggactc aacgagagct tagtagaaga
     3241 gacatttaga caattatcaa cccccttgaa ccctcttaaa gaagtgaatc tttttgaagt
     3301 agatacaggt tgaaaaataa aaggtgcaaa ttgccttata caatatatct atgatacttc
     3361 tgtaggtgtt gctccctttg cctagctacg tgtaggtggt atacttataa ctgcgtatgc
     3421 agtcttatgt atcatggagg aagttgtatg tcgttaaaaa attatgtcta ttcacatcct
     3481 gttaatgtgt ttatcattgg tcgtttggga ttatctgtgg aagtgttctg tgagctttat
     3541 ggttttaagc aggggacttt gtcttcttgg gttaccaggg aaaaaacagt tgcttctttg
     3601 ccgattgagt ttcttcatgg gttgtcctta gcttctgggg agactatgga tcaggtatat
     3661 gattgtttgt gtgtgttaga gcaggagtat attgagtata aaatagctaa cgagttaaga
     3721 aaaaggaaga agtatatcca gtagtagttt ttatttactt aaaaaattgg ttcattgagc
     3781 aacctatcgc tgctaaagta gcaaaggaaa acgttaaagg aaagaattta gggaagaaat
     3841 cgaaatgaaa tcggacgact ggattgaaca cacctggctt cctctgaaaa gaaatagcaa
     3901 acgaaagaaa ttttgggtat tgcaattatg gccattagga aaactttgta gttacggggc
     3961 acgacttatt cttgatttaa ccgtttactc gattggagta tttggaacgg cttattactt
     4021 gataaatgat cccaatagga ttgcagcatc agacattttt acagtgctaa tgacgttgat
     4081 ttttgtcatg ctattgtcta tttttactca attagtcatg caatttacca ggcaaaaatt
     4141 aacagcagga aaacttttca aaagcctatt cgatttaatt gttgtaaatg caattctagc
     4201 gactttaata aaacaaattg aacaatctgg aagaacaaca aaaggagtga aggatttttt
     4261 attgacgttt attcactttg taaatggaca catgtatttg tttgaagtgg gtattattct
     4321 cttttttgtc gggtatgtat ccacgaaact tattaaacgt tcaattgaaa aagaaattga
     4381 aattgacctg attccgacac ttcttggtta tgagtacaat gttgattttg gaagatatga
     4441 cgaattgatc aatacggata tcgttcacac gagtatccat gaatctactg ttaagggcat
     4501 cagatctatt ttaaaaaatg gccaggaaat gaaagcaata gatcgaagaa aagagatcta
     4561 caatttttat gaagtcgaag caagcctacg atatggcatc ggaaaattgt ggttagatgg
     4621 aagtaatatt cgtcaaaaca aaccatacat tttttggaac agtagtgatt tagaacttcc
     4681 aatgaaagat aaataattat ggagaatcgt ttgaaaatga ttcctctata caggattgtg
     4741 cttatagttg gcatggagtt aaaaacctta aagaaggagc agttattcaa agtgaaagaa
     4801 cgtcataatc agttactatg tagtaaaacg ggtacgatga acattgaata ccgaacagaa
     4861 tatttagaat taacgaatca aactgatttt ttgttgattc gaaagcaaca agagcaagaa
     4921 aaaaattaat ggctacttat agccaattga ttgatgaatg ggaacaattc aaggaatcta
     4981 aaattccaga acgtctctaa aagcctttat ttgtaaagag cataaggaaa cgtgggaaca
     5041 ctttttaaaa aaagtgttcc aataggctgt gcctattacg tttctcaaaa ataaatgtgg
     5101 gaacaaaata tttaaaaata ggatagtgaa aggatagtga aggatagtaa aaggagggta
     5161 gtaggatagc aaaaaggata ggctcctttt cgctatcctt tttaaattgg aggaattaat
     5221 atggaagtaa gaataagaaa tgtggatgag aaaatcgtaa gagaaattga tcgaagatgt
     5281 gacgaacggt tctgttgcaa agttttaaat ctactatcaa ataaggtaga ataatagaaa
     5341 aagatagcag gaggaatgac gatgaatc
//
LOCUS       DAFLWC010000128         5311 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.133, whole genome shotgun sequence.
ACCESSION   DAFLWC010000128 DAFLWC010000000
VERSION     DAFLWC010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5311
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.133"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(73..1221)
                     /gene="nagA"
                     /locus_tag="L1V17_002731"
     CDS             complement(73..1221)
                     /gene="nagA"
                     /locus_tag="L1V17_002731"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBN1237434.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1297..2133)
                     /locus_tag="L1V17_002732"
     CDS             complement(1297..2133)
                     /locus_tag="L1V17_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1237435.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2317..3534)
                     /locus_tag="L1V17_002733"
     CDS             complement(2317..3534)
                     /locus_tag="L1V17_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBN1237436.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3683..3862)
                     /locus_tag="L1V17_002734"
     CDS             complement(3683..3862)
                     /locus_tag="L1V17_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237437.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            3917..4000
                     /locus_tag="L1V17_002735"
     tRNA            3917..4000
                     /locus_tag="L1V17_002735"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3951..3953,aa:Leu,seq:gag)
     gene            complement(4240..4818)
                     /locus_tag="L1V17_002736"
     CDS             complement(4240..4818)
                     /locus_tag="L1V17_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237438.1"
                     /translation="MNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNT
                     MGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGI
                     YLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKE
                     LMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
     gene            complement(4824..5207)
                     /locus_tag="L1V17_002737"
                     /pseudo
     CDS             complement(4824..5207)
                     /locus_tag="L1V17_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347134.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1653 a         1082 c          838 g         1738 t
ORIGIN      
        1 ttttactaga acacaaaaaa aaccttaaaa ccaaacttaa gaagtttagt tttaaggtta
       61 acttaaatta tattatgcgt ggaaacgttc cacgccatct agataagttg cttccaatgt
      121 catatcaggg ttcaatacga taaagtctgc atcgcgtcct tgagcgattt ttccacatgt
      181 atcatcgatt ttacagctga ttgctggaat cagactagcc atcatgactg cttgttctgg
      241 tgttgctaat ccccagtcta caacattttt aattgcttct ttcaatttca atatacttcc
      301 agctaagttg ccagattcta gacgtgctgt tccttctttt actactactg gaaattcgcc
      361 taaattgtaa tttccatcag gcatcccacc ggccatcata cagtctgtaa ttaatgcgac
      421 atgatcatgt cctgcttttt ccattaggat tcccgcagca tttggatgta catgatggcc
      481 atcacaaatc aattcagaaa agacatgttc taaagataat aacgcaccca ccatacctgg
      541 ttcgcgatga ttcaatccac gcataccatt gaaagcatgg acaaatacac ttgcgcctgc
      601 ttcaacagct ttttgcgctt cttctagtgt agcattactg tgtcctagag aaacaactac
      661 tccttcttca gtcacttgtt tgacaaactc ttctacacct tgacgttccg gtgctaaagc
      721 aatttttttg attaaaccac ctgaagcttc ttgccattca tggaaagtat ccaaatcagg
      781 atccccgaaa taacttgggt tttgtgcccc tttgtgttct tctgtgaaga aaggaccttc
      841 aaaatagatt cctttgattt tagctcctgg tgcttcctga tacattttgc cgattgtctc
      901 agctacatct tttaaacgtt ctttgcttga cgtcaatgtt gttggtaaaa atgaagtcac
      961 tccacaagat aacagacctt cagacatcac tttgatgcct tctgcatcat tatccattac
     1021 atcatgattc atatagccgt gaatatgtgt atctaccaaa ccaggagcaa tccatttgcc
     1081 gctttggtca atgatgttga cttctccctc aggtagttct ttggtgtatt caccaaaaag
     1141 tccatcggta atttcaagat agcctgcatg tttgacacct gacgctaaaa agaatttgtc
     1201 agcatagata aaagttctca ttctattctc tccctttgtt tttctacctc taaagtactc
     1261 ttatttagag aagaagtcaa gaatggtcta caccatttac aaattttttg aaatttgttt
     1321 cacagcttgt gctaagcctt catagaatgc tgctctttct ggttcttctt tacgcttgta
     1381 tattaagctt ttaagcacaa ataaatcatt gaggtaatag tagctattct tctcttgagc
     1441 ccaatagatt ccttgattca cctgttctaa cgcttcgtcg atttcatttt gatggaataa
     1501 gaaatttcca taattataaa aaatttgcga aaattcactt tttgatcgtt catcagctga
     1561 ttgatgcagc agttggatgc ttcgactcaa atagtagcgt gcttcagccg tttttcctgc
     1621 cacaccatat atttttccga tacaactaat cagttgtatt tctgtgtcag aaacatggat
     1681 tctttctttt tggctagagt agcttaatgc ttctttcaaa taataaaggg actgagagat
     1741 attttgacgc aacgtgaatt cgcaaacacc gagataataa taatagcgtt gaaagtcagt
     1801 tgcttgatac agattttcag aaatatcaga agattttagt acttgttcta acttccgata
     1861 atcacgtttt tggaaacaac tatccaacag ttcaaataat ttatcgtttg tccgagtagt
     1921 ttttcgagag agattcatca catgatcaat cgttacccct agccgttgac aaatctgcat
     1981 catcaccaat acattcggca gttcctcatt attttcgatc cgacttaata cactttgtga
     2041 acaaatatca tgcgaaagca ttttttgcgt cattttttgt tcttttcgaa tctctttaat
     2101 gatcgttcca aaggactcga ttaacgtttc cataagtatc ctccccaaaa tatgcgtatt
     2161 cgcattctat tcgtatttta ctttaggaag tcgcaaactt caagaaaaga cttgcaacta
     2221 aataatatac tttagttatt taagaaaact ccactagaaa gagagcctca gtgtgtttgt
     2281 ctgtggccct cctactgaaa aatttggttt ttaaaatcat ttttggcgat aggttgctag
     2341 gaattctctc attttcttag ctgtttgttt caaatcatcc attttaggaa gataaacgat
     2401 tcgaaaatga tctggctggt tccaattaaa tccaccacca tgtacaagta gaatatgatg
     2461 ttcatgtaaa aagtccaaaa cgaatttttc atcatccaaa atattgaatc gctttgtatc
     2521 aatttttggg aatatataaa aagcagcttt tggttttacg gctgaaagac caggaatatc
     2581 attgattgca ttatagatat attctctttg ttcatagatc cttccgcctg gcaggagcag
     2641 ctcatcgaca ctttgataac cgcctagcgc ggtttggata atttgctgag acaatacatt
     2701 ggaacacaaa cgcatggagg acaacatatt cagcccttct atatagcctt tgacgtgtga
     2761 cttatctcca cttaggacca tccagcctac tcgaaatcct gctacacgat gagatttgga
     2821 tagaccgttc agcgtaacaa cgaacaaatc aggcgctaat gtagcaatcg gaatatgttc
     2881 tagaccatcc atcactaagc gatcatagat ttcgtcggaa taaataatca ggttattttg
     2941 tcgagctact tcaacgattt cttctaataa ttcttttgga taaagtgccc cagtaggatt
     3001 attaggatta atgataacaa tagcttttgt ccgactcgtt atttttgatt tgatatcatc
     3061 aatatcagga taccattctg cctcttcatc gcaaatataa tgaacaggtg tgcctccagc
     3121 taatgcaata gaagccgtcc acaacggata gtccggcatt ggaaccagta cttcatctcc
     3181 attgtccagc aacccctgca tacacatcgt gatcaattcg ctcactccgt tgccggtgta
     3241 gatatcattg atcgtcacat tcggaaaatg tttcagttgg caatattgct caattgcttt
     3301 tctagcagaa aagatcccct tggaatctga gtagccttct gagtcacggg cattcatgat
     3361 caaatcacga atgacttcgt ttggtgcttc aaatccaaaa ggtgcgggat ttcccgtgtt
     3421 caattttaaa atactaatgc cctcttcttg catccgctcc gcttcttcta gaacgggacc
     3481 gcgaacatcg taactgacac cttctaattt gttggatttt tcaaattctc tcatcactta
     3541 gccaatccct catttcaaaa agttagaact ttccaaattt tttgttattt actatttcaa
     3601 tatcatactc catcctagaa aattttgcca cttatttagg aaaaacgtaa gtattaaaaa
     3661 aacacaaaca agcgttgaga acttaattgt catgatagtc attccataga ttcgctgccc
     3721 aatccattgc aattccacaa atgattccta gcataaaacc aagcaaaaaa cgtccgaatg
     3781 caagtccaat caatacacct aagatcattc ccagtcctga aaattctccg tcatatttct
     3841 ccatcttaat aagtcctccc atttttgagc ttgacaacta tgtaaaacct cgctatcatt
     3901 agtgtgttat tattacgcag atgtgttgga attggcagac aagcatgatt gagggtcatg
     3961 tgagcgttag ctcgtgtggg ttcgagtccc atcatctgca ctacaactcg tgaagttaat
     4021 tttgcttcac gagttttttt gtttgaacgt ttctttatgc cattatatac atatcactgt
     4081 atcctttaca aaaagaacgt acaatcatgt aaacagcctg aggtgagtat atgaaggtcg
     4141 gaaacaagct actcgtagaa acttgcaagt gttaaaacaa ttaatcgaaa aacgagtaaa
     4201 atccctcacc taatactaaa gcgagggatt ttttgtatat tatctgttta tcaccgttat
     4261 tataaaggta caaataccaa gcacggttaa tccaaattgc ataaattcat ttttttgtac
     4321 actcatgctt ttcattagct ctttaactgc cattagtact aagatggcga taacaacata
     4381 aagtatatag tacgtccgca ttccggaagc ccatactgtg ggagaaaatc ccataattaa
     4441 ccttgaacaa aatcccatta tcatcaaaat aactaaaaaa atagaagttt tcttattgtc
     4501 aaaacttaaa taaattccaa caattaaaca tagtaataat gccaagacta ctaaagtagc
     4561 tatccaagta cctggataaa aaagtgacag tttcgttcct aactctgtaa agagattatt
     4621 caggttacta ctactccaaa tcattgccct tttatttcca ttgacgtaag taaagctttg
     4681 acccattgta ttaccaaaat aaataatcag gtttaagaaa aacggtaatg cagtcaatat
     4741 acgcacataa tagttttgac atttcctata tgttagaagg aaaattaaga aaaatagcaa
     4801 taaaaataag atattcatgt ctaaaaaaac ggctttccaa atgatgaaat acctaaatct
     4861 aacttattaa gaaagttgaa atttttatat tcaggaaacc atttattaat ttcatgtgca
     4921 gcacgtaatg cattccctgg agttgtcaaa gagaaaatta attctgctaa gcttattatt
     4981 gaaaatactg ataacttata attatatcgt ccattgacaa tcaaatataa actaactata
     5041 cttgttagaa caaaaaaaca ggcgttgact tgttcttgat tagttaaaaa tatcaataaa
     5101 ggaatactta cccaatatat ttttctattt atttcttctc ctcttaagag ttgaaaaaac
     5161 ggataaaaag ttagtaaact aaatgctact ggccactgat agttcaaggt ggttgctctc
     5221 caaccggttt cccccattac tgtcaatggt attaaacagt atatagagca aaccaataat
     5281 aaatttttaa catttatttt ctcaaaaaca t
//
LOCUS       DAFLWC010000129         5255 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.134, whole genome shotgun sequence.
ACCESSION   DAFLWC010000129 DAFLWC010000000
VERSION     DAFLWC010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5255
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.134"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            32..388
                     /locus_tag="L1V17_002738"
     CDS             32..388
                     /locus_tag="L1V17_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine-rich SFCGS family protein"
                     /protein_id="HBN1237439.1"
                     /translation="MIKVVIADRMGKGQNVAKGVEAAGGKAVVVPGMGADMRLGDVMQ
                     QEHADMGISFCGSGGAGALTAATKYGYPERHGMRSIEEGITAIKDGKTVLGFGFMDQE
                     ELGKRLTEEFIKKHGK"
     gene            404..754
                     /locus_tag="L1V17_002739"
     CDS             404..754
                     /locus_tag="L1V17_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4312 family protein"
                     /protein_id="HBN1237440.1"
                     /translation="MSVQKTIQQKVIVSGKGETKQHAFASALAEIQNKIMEQSNVLLR
                     IEPVNVDILKAVENKYTERFLFFFFPRQRISYEVELSVTVAVTEIKLADISFSQQMTE
                     DPNGIAIPFVTKKI"
     gene            783..1562
                     /locus_tag="L1V17_002740"
     CDS             783..1562
                     /locus_tag="L1V17_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4311 domain-containing protein"
                     /protein_id="HBN1237441.1"
                     /translation="MDFVIILVKSVIIGGLLGFAASVGAARMFHAPNTQGLGAFRTLG
                     EMNACMGDPASHFSFGLGFFFNAWASSVGAGAFTQDVTHRIIPNWAAAALLAKNKDVT
                     QTMHDPKKMGIIGAVIGAVVVAFLNTTAAAIPEALQVTAVSVLVPAATILINTVMPVI
                     FWLAALDAGKRTGFWGTLFGGIAQLIMGNAVPGVVLGILIGKGVDESGWNRVTKSMMI
                     AIVLLFIFSGFFRGFDMEMIKSFQLQVPNWLDNLHNIFSVK"
     gene            1573..2235
                     /locus_tag="L1V17_002741"
     CDS             1573..2235
                     /locus_tag="L1V17_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4310 family protein"
                     /protein_id="HBN1237442.1"
                     /translation="METTEEQAKVLEAKRQKSFWFADWSFPLIVGIMSAAVFAGTHMY
                     VMYGVGAFNEVSIVAMLKAGLDGGSYGAAAAFGASFLFARILEGSLVGILDLGGSILT
                     GIGIGVPAILLSMKIAAPIDNFALSLLTGLVLGLIVGGIIVLIRKFTINQSNSTFGAD
                     VMMGAGNSSGRFLGPLIILSACAASIPIGIGATLGALGFYAWKKPIAGGAILGAIFPA
                     VN"
     gene            2254..3360
                     /locus_tag="L1V17_002742"
     CDS             2254..3360
                     /locus_tag="L1V17_002742"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HBN1237443.1"
                     /translation="MFDTLIKNGRLVDGSKIEVAIEKGMIKAVAAEINQPAQEVVDLE
                     GKYYLSAGWIDDHVHCYEKMNLYYDYPDQIGVEKGVTTVIDAGTTGAENIREFYQLTK
                     SVKTNVYALMNISKWGIVKQDELADLTKIQEDLVSTALAELPEFIVGIKARMSKTVVG
                     ENGIKPLELAKKIQTENNDLPLMVHIGSAPPELEEVLSRMERGDVLTHCFNGKPNGIL
                     DPKTDQIKNFVWDAYNNGVVFDIGHGTDSFNFHVAETALKAGMKATSISTDIYIRNRT
                     NGPVFDLATTLEKLRVVGYSWEEIIEKVTAVPARNFHLKNKGQLAVNYDADLTIFEIV
                     ENEKELKDSNGFTRIAKEQILPIKTIIGGVIYDN"
     gene            3350..4441
                     /locus_tag="L1V17_002743"
     CDS             3350..4441
                     /locus_tag="L1V17_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HBN1237444.1"
                     /translation="MTISYGKFDLKEVINASGKMTILGVSKVSESVLAAQRFGGEHFF
                     EMSDLAIKTGAYLSQLLKVEDAQIVSSASAGIAQSVAALIGQGDMYHVYHPYTEKIAR
                     REIIIPKGHNVDYGTPVEVMVAQGGGKVIEAGYANMCTPEHVSMMITEKTAALLYIKS
                     HHAVQKSMLTVAEMVEVAKAHRLPLIVDAAAEEDLFKYSEMGVDLVIYSGAKAIEGPS
                     AGLVIGKKKYIQWIRLQSKGIGRAMKIGKDNILGFTQALEDYLKNGSESGDSMKQRLA
                     PFVNAINQLPDLSAKIVQDGAGRDIYRASVTINGDKSAKEVIQELKARNPAVYTREYQ
                     ANNGIIEFDIRSVSQNEMEKIIKRLREIM"
     gene            4454..5194
                     /locus_tag="L1V17_002744"
     CDS             4454..5194
                     /locus_tag="L1V17_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HBN1237445.1"
                     /translation="MSVIPNYYKNRVCLNVLAHSVENAKACYEAAEGHVVLGVLSKNY
                     ASDEAAIEDMKRYQDATNNALSVGLGAGDPNQSQMVSRLSGVLQPQHVNQVFTGVGTS
                     RALLGQNDTVINGLVSPTGKIGYVNIATGPLSSQAPAAEVPIETAIQMLQDMGGTSIK
                     YFPMKGLAHREEFKAVAEACAKYEFYLEPTGGIDLSNFEEILKIAIDAGVKKVIPHVY
                     SSIIDKETGDTRIGDVKILLSMVKKIIH"
BASE COUNT         1685 a          864 c         1253 g         1453 t
ORIGIN      
        1 acaaatgata ttttacgagg aggaaacaat catgattaaa gtagttattg cagaccgtat
       61 gggtaaagga caaaatgtgg ccaaaggggt agaagcagct ggtggaaaag cagttgtcgt
      121 accaggaatg ggggcagata tgcgtttggg cgatgtgatg caacaagagc atgcagatat
      181 gggtatctct ttttgtggta gtggtggtgc aggtgcatta acagcagcaa caaaatatgg
      241 ctatccagaa cgacatggta tgcgttcgat tgaagaaggg atcacagcta tcaaggatgg
      301 caaaactgtt ctaggtttcg gctttatgga tcaagaggaa ttagggaaac gtctgacaga
      361 agaatttatc aaaaagcatg gaaaatagaa agagggacat gaaatgagcg ttcaaaagac
      421 aattcagcaa aaagttatcg tctccggtaa aggggaaaca aagcaacatg cttttgcatc
      481 agcgttagca gaaattcaaa acaaaataat ggaacaatca aacgtattat tgcgaatcga
      541 accagtcaat gtggatattt taaaggcggt cgaaaacaaa tacacagaac gctttctatt
      601 tttcttcttc ccacggcaac gtattagcta tgaagtcgaa ctctctgtta ctgtggctgt
      661 aacagaaata aaattggcag acatatcgtt cagccagcaa atgactgaag atccaaatgg
      721 gattgccatt ccatttgtaa ctaaaaaaat ctaattttga atcataaggg ggaaagaata
      781 acgtggattt cgtaatcatt ctagtcaaat cggtcattat cgggggatta cttggttttg
      841 cagcatctgt cggggcagct cgaatgtttc atgcacctaa tacacaaggt ttaggagctt
      901 ttagaacatt aggcgaaatg aatgcctgca tgggtgatcc agcttctcat ttttcatttg
      961 gtttaggctt tttctttaat gcatgggctt cttcagttgg tgctggtgca ttcacacaag
     1021 atgtgacgca tcgaatcatt cccaattggg cagcggcagc acttctagca aaaaacaaag
     1081 atgtcaccca gaccatgcat gatccgaaaa aaatggggat cattggagcg gttatcgggg
     1141 cagtggtggt agccttctta aacacaacag ctgcagcaat tccagaggcg ttacaagtga
     1201 cggcggtttc cgttttggta ccagcagcga cgattctgat caatacagta atgccagtta
     1261 ttttttggtt ggcagcttta gacgcaggga aacgaactgg tttttggggc actctttttg
     1321 gtggtatcgc gcaattgatt atgggaaatg cggtacctgg tgttgttcta ggaatcttga
     1381 ttggtaaagg cgtcgatgag agcggttgga atcgcgtcac gaagagcatg atgatcgcta
     1441 ttgttttatt atttattttc agtggatttt tccgtggatt tgatatggaa atgatcaaga
     1501 gcttccagct tcaagtgcct aattggcttg ataacttgca caacatcttt agtgtgaaat
     1561 aggaggagaa tcatggagac aacagaagaa caagcaaaag tattagaagc aaagcggcaa
     1621 aagagctttt ggtttgcaga ctggtctttt ccgctaatcg taggaattat gtccgctgct
     1681 gtatttgcag gaacacacat gtatgtgatg tatggtgtgg gtgcattcaa tgaagtttcg
     1741 atcgtggcga tgttaaaagc cgggctggat ggcggatcct atggcgcagc ggcagcgttt
     1801 ggtgctagtt tcttatttgc cagaatttta gaaggctctt tagttgggat cttggactta
     1861 ggcggttcga tcctaactgg gatcggaatt ggggtaccag caattctctt aagtatgaaa
     1921 atagcggcac caatcgataa ttttgcactc tctttattga ctggtttggt tctaggtttg
     1981 attgttggtg gcatcattgt cttgattcgt aaatttacga tcaatcaatc aaattccact
     2041 tttggtgctg acgtcatgat gggggcagga aattcatctg gacgtttttt gggtccatta
     2101 attatattaa gcgcgtgtgc agcatctatt ccaatcggca ttggcgctac attaggagca
     2161 ctaggattct atgcttggaa aaaaccaatt gctggaggtg ctattttagg agcaatcttc
     2221 ccggcagtaa attaatagaa agagggtcat taaatgtttg atactttgat taaaaatgga
     2281 aggttagttg atggatctaa aatagaggtc gctatagaaa aaggcatgat taaagcagtt
     2341 gcagcagaaa taaatcagcc ggcgcaagaa gtagttgact tggagggaaa gtattattta
     2401 tccgctgggt ggatcgatga tcatgtccac tgctatgaaa agatgaatct ttattatgac
     2461 tatcctgatc agataggggt cgaaaaaggt gtgacgacgg tcattgatgc tggaactacg
     2521 ggagcagaaa acatccgtga attttatcaa ttgacgaaat cggtcaagac aaatgtgtat
     2581 gcgctaatga atatctctaa atggggcatt gtcaaacaag atgaacttgc tgatctaaca
     2641 aagattcaag aagatctagt aagtactgcg ttagcagaac tgccggaatt tattgtcggg
     2701 attaaagcga gaatgagtaa gacagttgtt ggtgaaaatg gcattaagcc attagaatta
     2761 gctaaaaaaa tccagacaga aaacaatgat ctgccattga tggttcatat cggttctgca
     2821 cctcctgagt tagaagaagt attgtcaaga atggaaagag gcgatgtatt gacccattgt
     2881 tttaatggaa aaccaaacgg tattttagat ccaaagacag atcaaattaa aaactttgtc
     2941 tgggatgctt acaataatgg tgtcgtcttt gatattggac atgggacgga tagctttaat
     3001 ttccatgtgg cagaaaccgc actaaaagca ggaatgaaag ctacctctat tagtacggat
     3061 atctacatcc gcaatcgtac aaatggccca gtttttgatc tagcaactac tttagaaaaa
     3121 ttgagggtag tcggctattc ttgggaagaa atcattgaaa aagttacagc agttcctgca
     3181 cggaattttc atttgaagaa taagggccag ttagctgtca attatgatgc agatttgacg
     3241 atatttgaga ttgttgaaaa tgaaaaggaa ttgaaagatt ccaacggatt tacacgtata
     3301 gctaaagaac aaattttacc gattaaaaca attattggag gcgtcatata tgacaattag
     3361 ctatggaaag tttgatttaa aagaagtcat taatgcatcg ggaaaaatga cgatcctagg
     3421 ggtttctaag gtatctgaaa gtgtcctagc agcacaacga tttggaggcg agcatttttt
     3481 tgagatgagt gatcttgcca tcaaaaccgg cgcttatctt tctcaattac tgaaagtgga
     3541 agatgcgcaa atcgtttctt ctgcttcagc agggattgct caatctgttg ctgctttaat
     3601 cggacagggc gacatgtacc atgtctatca tccctataca gaaaaaatcg ctagacggga
     3661 aatcatcata cctaagggac ataatgtaga ttatgggaca ccggttgaag taatggttgc
     3721 tcaaggtgga ggaaaagtca tagaagctgg ctatgcaaat atgtgtacac cggaacatgt
     3781 ttccatgatg attacggaaa aaactgctgc gcttctatat attaaaagtc atcatgcagt
     3841 tcagaaaagt atgctgacgg tggcagaaat ggtagaagtt gccaaagctc atcgtttgcc
     3901 attgatcgtt gatgcagctg cggaagaaga tttattcaaa tatagcgaaa tgggcgttga
     3961 cttagtgatt tactctgggg caaaagcaat cgaaggtccg agtgccggac tggtcatagg
     4021 aaaaaagaag tatattcaat ggattcggct acagtctaaa ggtattggcc gagcaatgaa
     4081 aatcggtaaa gataatattt taggctttac ccaggcacta gaagattatt taaaaaatgg
     4141 gagcgaatcc ggtgactcca tgaagcaacg attagcgcct tttgttaacg caatcaatca
     4201 acttcctgac ctttcagcga aaatagttca agatggtgcc ggcagagata tttatcgagc
     4261 aagtgtaacg attaatggcg ataaaagtgc gaaagaagtc attcaggaat taaaagcacg
     4321 aaatccagca gtctacaccc gagaatatca agcaaataac ggaatcattg agttcgacat
     4381 tcgttccgtc agccaaaacg aaatggaaaa aattataaaa agattgagag aaatcatgta
     4441 ggaggctttt aaattgtcag ttatcccaaa ttattataaa aatcgtgtat gtttaaatgt
     4501 attagctcat tcagttgaaa atgcaaaagc atgctatgaa gcagcggaag ggcatgtcgt
     4561 actaggtgtg ctatcgaaaa attatgctag cgatgaagca gcaatcgaag atatgaaaag
     4621 gtaccaagac gcaaccaata atgcgttgtc agttggatta ggcgctggag atccaaacca
     4681 aagtcagatg gtttcgcgtt tatctggggt tttacaacca caacatgtca atcaagtatt
     4741 tactggcgtg gggacttctc gtgctttatt gggccaaaat gatacagtca tcaatggatt
     4801 ggtttcacca acaggtaaga tcggctatgt caatattgct acaggtccgt taagttcaca
     4861 agcgccagca gctgaagtgc ctattgaaac tgccattcaa atgctgcaag acatgggagg
     4921 tacttcaatc aagtatttcc cgatgaaagg cttagcacat agggaagaat ttaaagcagt
     4981 tgcggaagct tgcgcaaaat atgaattcta tttagagcca acaggaggaa ttgatctttc
     5041 aaactttgaa gaaattctga aaattgcaat cgatgcaggt gtaaaaaaag tgattcctca
     5101 tgtttatagt tcaattatag ataaagaaac aggagatacg cgtataggag acgtaaagat
     5161 actattaagc atggtaaaaa aaattattca ctaactcatt agaaaataag aagcttattc
     5221 cagaatgaaa ttaaatggaa taagcttttt ataat
//
LOCUS       DAFLWC010000130         5181 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.135, whole genome shotgun sequence.
ACCESSION   DAFLWC010000130 DAFLWC010000000
VERSION     DAFLWC010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5181
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.135"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(1237..1902)
                     /locus_tag="L1V17_002745"
     CDS             complement(1237..1902)
                     /locus_tag="L1V17_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1237446.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            2082..4064
                     /locus_tag="L1V17_002746"
     CDS             2082..4064
                     /locus_tag="L1V17_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBN1237447.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            4068..4706
                     /locus_tag="L1V17_002747"
     CDS             4068..4706
                     /locus_tag="L1V17_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1237448.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            4734..5162
                     /locus_tag="L1V17_002748"
     CDS             4734..5162
                     /locus_tag="L1V17_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237449.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
BASE COUNT         1701 a          793 c          948 g         1739 t
ORIGIN      
        1 actacctgta ttagtcctct tttttgacca gattttgacc agtctatttt acattctaat
       61 atattcatat gagctaattt tatgattaaa tggtaagtgt ttccttgttt gttttagttt
      121 aaactagtgt gtaatttaaa aatctatatg gaagggtctg tggggtaata cttaaataaa
      181 ggctaggaac ctgataacat caaggttcct agccttttta taataaaatg aagcgaaaat
      241 aatttctttt aaagagccga gattatcagc tatataagag tgaatttgat gcaaaaaaca
      301 gagccgaaac agtcttggtg ttcgtagctc tgcttatatg tttcgaattt aagacaaaga
      361 gttggcaaaa gatgttgata aggaagataa gataactgtg ttatataaac taggtaacta
      421 actgtaacaa gctaatttta agagattctt attagaagac gtttaggaat ataactaaga
      481 aaatgattat acaggtaatt gtcatttcaa taatgttttc taattttcgc gtctttgttt
      541 taagaaaaag gccagaatca gttggaaaaa agttcgtacg atagtgaaga ggggcaaaat
      601 ttcctactaa tattcccact aacaagagat aaaacggcca ggttggtgtg attcctctat
      661 aaaaaaatgc ccatgctacc gaaatcccat agattaacaa ctgaacaatt tttacaatga
      721 aaaaattgtt ctgccattac tcaaagtctc ttcctccttg tatcgtttat ttgtttcatt
      781 ttatcattat gataggcgct tgaacaatcc attttgtatt ttattgagta ctcttggata
      841 aactaccagc gattatcata tttatttatg ttactgtaag ccatcatata aaagtaaatg
      901 agcagatcat agaaatataa aaaagaacta aaattgatct aaattatgtg cagcttgact
      961 acgtaccaat ctatattact tactagattg gtcgttaatc tattcggatc gaatgagcaa
     1021 aatatttttg tgaatgtcca tccttgatta tgattccaaa aagaatcatt gggaggctgt
     1081 ggcgtaaata ttatactata agccagaaat acctatcatt ctgaactttt ttatttagga
     1141 actttcatct caaggctttt tcaattaatt tgtacccctg ttttttggat aagatcatgt
     1201 gcattgattt tttctatctc tacgttcatc tcctacttaa tgcctatctg gctcctgagg
     1261 gcttcttttt aaggcgtcgt catagtcttg gctgaggatt tcttggtaat ctgagggaat
     1321 ggcttcccaa gtgagcaggc gaacgttcat gacgtgtttt cctttgtgtt tgattacagc
     1381 atggtttttc tctttttcta cctctccagc gtgaaaagac agccatgtac catggccaaa
     1441 gatatcatta catacccaac gttcgatgga attgtccacg tatcctacag ggagtgtggt
     1501 atagccgatt tgtggtttca aaaaaggatt gaatcgatcg atcgtttcat ttttgtattg
     1561 ataattgata agaaaaagat agaccaaaca aaagacgagc agaaagaaag atagtgtctt
     1621 tttgagtgag aagggttgtt ttgatgaata agatttcttg ttaacaagag gttcatctgg
     1681 caatgttggt tctattgatt cggtagctga ttcaatagaa ggaaaatcaa tcggcagacc
     1741 taaagtatga tgtaaaagtg acagcatttc aaggtctggc attgtacgag aattttccca
     1801 actagaaatc gttttatcgg aaacaccaat tttttcgcct aattcttttt gcgtaagctt
     1861 acaatttctg cggtaagttc gtattttttc tccggtgttc atcttcttct cctttcgatt
     1921 ctacagtata tagatttatt ctacatgacc tatacacttg atagatacgt ttttttgatg
     1981 aaaaacggta tgattttatc aaagaatcat ttaagtaagg gagagtggtg ataatcaaaa
     2041 aaaagttcac agttttactc acaatcatag tgaccggtat catgagtggt tttgccttgg
     2101 ttagtataaa taaacaggta ctctatcgga caaatgaatt tttccatcaa acagatactt
     2161 atactccgat tcgattgcca caacatttta ttgggcaaga agaatatgag cagctaatca
     2221 tggtatttga aaatgtctca tcagaaactg agctttctta tatgaaaaaa acagtaaatg
     2281 aatccaatga agtagataca tcttggaact tcaagataca gccaaagctt gaaatgacat
     2341 tgtattatca aggggatgtc aaatcttctc acgagaaggt accctattct aatacctcct
     2401 ttcgcgtaac gtccattgaa gaatcgatca aaataaaaga ttttgaaggt gaatttttct
     2461 tgatgacgag agaaaaagaa gcctatgaac ggttcatttc actattcact gatcgattca
     2521 atcaagcatt tcacactgat tatgccacta atatttttga agactttgaa aatagctatt
     2581 cgtattcggt tatttcaaat acagacgtat ataattatcg agtgtattta actattggat
     2641 tgattctttt attccttttg ttatcatcct ttttcttatt gatgaataaa gaaatcagtt
     2701 tattgttgaa taatgacttt tcattacatc aagtattgtg gtgtttattg gggaaaaaga
     2761 aaatcattat tacattcata attgcaggaa tcattggtgg ttttattttt atgtattata
     2821 aggagcaatt tctttatttg ttccagatgt acgttttctt gttcagcgga atatatggta
     2881 tctctttgat ttctctttta ttagttgaaa aaatcgcttc gttaagagaa gcgttcaact
     2941 atatccaata cattcttttt acatttggat tgttgttttc tcttcttttg accgttgcca
     3001 atgtcgaatt agcaactatc gttttttctt cttcacagtt agctgtttcc catgaaccac
     3061 caaaagaaat cgctggtgag gactatcatg tattttatcc agtaaccatc gggaaaaacc
     3121 acgtggattt tatttattcc aatcgttttg catcagcagc agatcaggaa ttatatgaaa
     3181 ctttgaataa aaacggaagt atattagtca atgtatcaga ttacttgaat gaagaaaatg
     3241 aacagtttgg cagagggata aaaataaatc tgaattatct taagaaattt cctttgattg
     3301 atgtctctgg aaggttgatc caaataaccg aaaaagaaac gcaccctgtt atattgatcc
     3361 ctgaacgata tagacataca gatttaaaaa atgacctggc gcaaataaca gaatattatc
     3421 aagaaatcag tgaaaaagaa ccgaaatttc tatttataaa aaacaatcaa cccatttata
     3481 catttattcc ttctatcccc tggatcgaac attatccggt tgttgaaata ctgacattga
     3541 aaaacagtat gtatttggaa agaaatattc tcagcggaga aatctatcca ccgttaaaga
     3601 tcaagatagg ctctttgtcg aaagaaaggt tatttgagct gattgaagaa agtcagttac
     3661 gtgataactt gcagttatca tttccgtata ctcagactga agagatagct gtcaaagtgt
     3721 taagcagatc atttcattac ttgatacaga tatttttact cactttcttt tctttcttct
     3781 tgttgagcta tgtcatgtta tgcatatatt ttgtctacaa ttgtcggaaa atcgctatct
     3841 ttcgttcaag tggttattcg ctctttgaaa cgtataaaga tttcttcatg atgaacctca
     3901 tcaaatgggg aacgacaagt gtaatcttcc tttttcttat agaaagagag cctaaatatc
     3961 tttttaatat ttttttcttt agcttcattg attttattct ttcagttgtt tttattttgt
     4021 ctacagaaaa gaaaagtcag ttattgctga tgaatggagg ttaacaattg gagccgttga
     4081 tagtgataaa aggtgcgaaa aaaatcattc gaaacaaaac gattcttcat ttggatcgtt
     4141 tcactgcgga tgctggggat cttgtgactg ttgttggaga aagtggagca ggtaaaagta
     4201 cgttattgaa tatattagga ttgaatgatc agttcagttc aggacaattc tatttgttcg
     4261 atcaagagac gaaacaatta actgggagag agaagcgctt gataaaaaga aataccatat
     4321 cttttctttt tcaagatttt gggttgattg aatatgaaac aatcgatttt aatttagata
     4381 ttggattgaa gttttcgaat ttaaatgttt cagataagcg aacagcaaag tatgaggcat
     4441 tgaaaaaagt aaatataaac aagaagctaa gtacgcctat ctacacatta tctggtggtg
     4501 agaagcaaag aatcgcctgt gcgagagtct tattgaagaa tagcaaaatc attttagccg
     4561 atgaaccgac tgggtcattg gataaaagaa ataaggataa agtagttgaa atcttatcgc
     4621 aacaagcttc ccaaggtacg ttagttatcg tagtcacgca tgatccatat ctgaccaaaa
     4681 taggaaacaa gaagatcatg ctttaaaaat caaaaaggaa aggatgtcgt tttatgaaaa
     4741 aagcagttat tatttgtgca ctagggatag gttttgttgg aggaaacgct atgtcatctg
     4801 aagtggaagc aaattcagtt cacggtgaaa tctattacaa atctttaaag ccaggagaga
     4861 ttcattttga tgctaaaggt aatattatta agtcaaattt accagtagac cgggaaattt
     4921 ctagaacagc aattaatcat agctctggaa gatgggttta ttatagtgat acaacttgta
     4981 cgagaaaaac aggtcattct aaccactata gtcgtgtcta taatcgtcac ggtgcaaaag
     5041 cgaaagttgg aaactctatt cgatcagcaa atgcaacaaa aggagtatgg gcctatgcaa
     5101 gtgcgacagg aaatagaact gacacattct catgttggta caatccaacc ggttggtatt
     5161 aagtatccaa aagtttatat a
//
LOCUS       DAFLWC010000131         5178 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.136, whole genome shotgun sequence.
ACCESSION   DAFLWC010000131 DAFLWC010000000
VERSION     DAFLWC010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5178)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5178)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5178
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.136"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            247..1467
                     /locus_tag="L1V17_002749"
     CDS             247..1467
                     /locus_tag="L1V17_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HBN1237450.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            1464..4184
                     /locus_tag="L1V17_002750"
     CDS             1464..4184
                     /locus_tag="L1V17_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1237451.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            4168..5112
                     /locus_tag="L1V17_002751"
     CDS             4168..5112
                     /locus_tag="L1V17_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBN1237452.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
BASE COUNT         1924 a          846 c         1031 g         1377 t
ORIGIN      
        1 atacggaaaa atggagcata aattccagta caaatagtac ttcttcagtg tcaaacgaag
       61 cgaatataac atagatattt aggattgtga caaaaatcat gtcacaatct ttttttcgaa
      121 taaacttatt ttttgaagtc ggccatttat cgtaatttct ttgcataata cgaacaaatt
      181 ttcggttatt gatgaaaaaa aacattgaaa atggtatgat aaaagaaaaa aaggaggaaa
      241 tttttaatgg tgaaatttat ccatgcggca gatttacata tggatcggtc atttgaagga
      301 ctgacaactc ttgataaaac tgtacaggaa aaactattga agacgaatct gaccgtttta
      361 tcaaatatca ttgaacaggc aataataaat aacgttgatt ttgttttact tgcaggagat
      421 aattttcatc aaaatcgtcc ttcattaaaa atacagaaac atttttcaga acagatgaaa
      481 cggttagaaa agaaccatat acctgtattt ataatattcg gaaatcatga tttctatcaa
      541 aaagagcggt attggttctc ctttcctaaa aatgtccatt tatttacatc cgaaacggta
      601 gagacaaaaa aaataacgat aaaaagtgga gaaactgtct ctctcagtgg atttagttat
      661 cgtcaaccgt ggattcaaaa agacaaagtg atggaatttc cttctagaga actcacagat
      721 taccatattg ggttgtacca cggggaacct ggcgtctctc aaaaaggaaa ctatgctcct
      781 ttccaaccct caaagatgca agaaaaggga tacgattatt gggctttagg gcatatccat
      841 gtgccaacgg tcttaaatga aaagcaaaca attgtttatc caggtgcgcc tcaaggtcat
      901 actaaaaagg aacaagcttc tacatctatt ctactagttg aattaagtaa aggaagttgc
      961 caaatacatc cgattaaagt agcagaggtc tattggaaga caaaggaaat atcattgagg
     1021 aaagcaagaa cgacaaaaga ggtcattgtt cacattcgtc agcagctttc aaaagtagag
     1081 gatggattta gtttaattga gataaaatta aaagattatg accatctcaa tacagatgtt
     1141 ttggaacgga tacaatcagg agagctatta gactatttgt tagaggaatt ctcagatagg
     1201 ataaatgatt tctttatttg gcgtatttct ctcatagaga atacttttta tacgaagacc
     1261 ccacttgctg cttctgctaa attgatggaa cagttatttc aatactatca gacacctcaa
     1321 gatttccaac aaattttaaa tgaagtatat agtcatcaag aagcggctag aatattgagc
     1381 gaactgccgg aatatcaaga agaaacactt gaaaaagcca agcagctgct taatcaagat
     1441 tttttatttg aggaggatca ggaatgaaga ttttaaggat cgagattgct gcttttggaa
     1501 aatggcgtca aaaaagtttt gacttttatt caggcaatca gctgatctat gggggaaacg
     1561 aagcaggaaa atcaacgatt tatcaattta ttcaagcaat attatttggt ttcccttcaa
     1621 aaggccgtaa aaaaaaggat tatacaccaa aagacggctc agcctatggc ggcaaaatat
     1681 ggcttaaaca tcctgtatat ggtgaatttg ctgtcgagcg ctacaagcag caaaatcgcg
     1741 gaaaatcgaa ggtgtggctg ggggatcaag tgggaagtga tgagttacta gaaaaactga
     1801 tcgcaccttt gacgaaagag ttattccagc aggtatttac tttccagcaa gagcagttga
     1861 tggaactaga tcatttgaga gaaaaagagc tacatgatgc gctgatttct ttaggcatca
     1921 cgggcagttc tcaagtattc caaaagcggc aagaatatta tcagaaagca caacaattat
     1981 tcaagaaaaa aggccaaaaa ttactaatca atcaaaaatt aaatgaatgg aaagagctgc
     2041 aagaaaaaat tcatcaaaaa caagaacagg aagcttattt tggcaagttg atccaacaag
     2101 aacaggaata cgagtcgcaa cagcagcagt tattggcaca attaaaagag gcgaacaaac
     2161 aattttcatt agccagacag caagaactta atttttcttt atatgaagaa tggcaatctc
     2221 tcaaaaaaaa cagcactaca ggtcttcctg atgagcaact tcttttagat ctggagtctt
     2281 tctccaaacg gtatcagcaa acaaatgagc gtttggaaga attagaagca acactggaaa
     2341 agcatagcgg gatggatcag cagtcagcca gatattattt ttatttagag caggagcagg
     2401 aactaaaaga tctccagcaa cttcaattta cagcggaaca attaaacgaa gaatggcaaa
     2461 gattacaaat tgagactaga gaaacaaatt cagaattgaa gattttggaa caaaggtggc
     2521 attggcagaa aaatccgtta ccggaagaat ttttatatga agaagaatgg aagcatcttc
     2581 tggctgaaga aagaaggatt gctgatctag aaagccagat ttctgtgcgt ctccaaatag
     2641 ctaaagaaca gcaagagatg attgaagcag aagtgaatga cttggaagag acctatccag
     2701 cattattaca aaatcagtca gagatagcac cagtctcttc atctaaaccg tatatgctga
     2761 tggctggcgg agcaataatc attgcaggta tatttgtacc aatgcccttg aaagtgatcc
     2821 ttttactaat tggtgcaggc atgattggct atttcttcta caaaaggcaa ccaaaaatta
     2881 aaactaaaaa tgatttctct gagataaaag gaatgtggca agaaaaacta ggacaacttg
     2941 atctagcctt agctcaatta gctgaagcag aagaaaaaca aaagagaact ggagaagaaa
     3001 aacagattct tcagcaagaa gtatatcgtt ttgcggatca tcggcactta ggaaagatgg
     3061 atacgctcaa actcatgaaa gaatatggac aggaagtcat agattatcag aaattatatg
     3121 gcgtatttga gcggaaacat aaaagagaac aggaaataca agaaaaacta cgacaaatcg
     3181 accaaaaatt tgagtttgtt aaagaatggt taccgataca agataagaca atttcagaaa
     3241 aaatggtatt gctttcccgt tttatacaag agatggaaca gatgaaattt gccagaagct
     3301 atcagcaaaa tactttattg aagcaagaaa tcaatcaatt gaaaaagaaa caaaaagtat
     3361 ggatacaaga atacagcgaa caattgactc aagcaggctt atcttatcct tcggaagtac
     3421 ctgtcttttt acaaaaagcc aaacaagccg aacagcagat gaaaagatac aatgaattat
     3481 cggaaatgct tactccacta tttcctgaag agctgacaaa agagaaatta tctgtaagac
     3541 tgcgccaact gaaagaaaag caatcccaac tccagcaaga agaaaaagaa gcaagtgaaa
     3601 atcggcaacg actccaactt caagtagaag agttgcaaag agacggcaca ttggacgaac
     3661 tttatcaaca agctagccgg caaaaagcaa aattacagga attactggag gaatggggag
     3721 cacttgaaat cgccgggaca ttcttaggtg atctttcaac agagatgagt gaaagacaat
     3781 taccccagtt gttaagagca gcaggtgatt atttaggtat tttaacaaaa ggaaattatc
     3841 agaagatatt actgaaaaat gatacactga ctttaacaga cggatataca gaatttccca
     3901 tctatgagtt atctacaggt acgaaagatc agctgattat ggcgatgaga tttgcttacc
     3961 tctcattaga agctaaccgt tcgatatgcc cgatcatcat tgatgatggc tggcttcatt
     4021 atgatcatca gcgaaagtat caattagctg aacttttagc taaatttgga gaaaagtatc
     4081 aaataatttg tttttcttct gataaagaaa tggtaagcta ttaccatgag atgaaccaaa
     4141 tcgtaaaaca attagaagga gcaaataatg aaaaaaattc gtgatttagt aatcgatgag
     4201 cagtttgaac aatttgtcct gatcaaaagt gcagatgtaa gaatcgctaa aaacggaaaa
     4261 aaatttattg cttttacttt ccaagatact tcaggtacta tcgatggtaa atactgggat
     4321 gcttcggagg aggaaatcaa taaatttaca gccggcacag tcgtttttct aaacggtaaa
     4381 agagaggttt atcaaggaaa ccctcaagta aagattcttc atatgcgctt aacaagggta
     4441 gatgagccag gagagcctag tttatacatg gaaagagccc ctttgaagaa agaagaaatg
     4501 gaagaagaaa tcaatcaatt gttgtttgag atcaccaatg cgcattggaa tcgtattgtt
     4561 cgctatctac ttaataaata tcaaaaacaa ttttttgagt ttccggcagc aaaaagaaac
     4621 catcatgcat ttgccagtgg attagcttat catactttga caatgcttca cttagggaaa
     4681 tcaatcgccg atgaatatcc tgagctgaat cgagcattgt tgtatgctgg tatcattttg
     4741 catgatttag gaaaggtgat tgaactttcc ggtcctatgt cgacagaata tacgcttgca
     4801 ggaaatttga tcggtcatct ggtattgatt gacgaagaaa taactaaagc ctgtcttgcg
     4861 ttgaaaatca gcgaagctga cgaagatgtt ctcgtattac gtcatatggt tttagcacac
     4921 catggcttat tagaatatgg ctcacctgta cgtccaagaa taatggaagc agaaatatta
     4981 catcaaatcg acaatatcga tgcttcgatg cagatgatgt tgacttcgat tcgtcaaaca
     5041 gaaccaggaa aatacaccga tcggattttc ggtatggaca accgaagttt ctatgtacca
     5101 aaagatttat agcaaaaatt tatttttttc attcaaaaca aaaaaagcga gacataagtc
     5161 ttcgcttttt ttgttttc
//
LOCUS       DAFLWC010000132         5172 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.137, whole genome shotgun sequence.
ACCESSION   DAFLWC010000132 DAFLWC010000000
VERSION     DAFLWC010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5172)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5172)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5172
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.137"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            107..1153
                     /locus_tag="L1V17_002752"
     CDS             107..1153
                     /locus_tag="L1V17_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1237453.1"
                     /translation="MSVKISVIVPCYNVEKYIDECINSLINQTLKDIEIILLNDGSTD
                     NTLAILKKYEKLDSRIKVYEHKNMGLGPTRNRGIKIANGEFLAFVDSDDFVSNTMFES
                     LYNCAIAENADIAIGEVGIFSDREIERVKIRKSLTNLKTIELATYNKKEFFKQFYFNR
                     LYSHNAWDKIYRRSLVLEFNLSFGDNKIIFAEDNWFQLQVFMTNTRICFVDKLCYYYR
                     QQNNSIMHKPKSNLVFRHGNMIADYEKLIRQNGNNIIDKKACMLVAFDVLIMEIFNQK
                     NVGGTCEDYKNALVSLKHHKILRENISNIVRMKAYELEPNMRKKLALVTISIMFNFKM
                     YKTAYNMLWRIYNR"
     gene            1167..2246
                     /locus_tag="L1V17_002753"
     CDS             1167..2246
                     /locus_tag="L1V17_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBN1237454.1"
                     /translation="MRKLTFVIGIMGKGGAERVIANLANNFIQDNWEIDIITIYGNRQ
                     DYELNRKIQVHPIICKSSFRAFRPLERFKELRKKIREIQPDLVISFLADVNIHVIISL
                     LGVKQKLIVSERNDPQRNPEEPWIRKIRDFLYKNVDGIVFQTPDAKKYFSKINDKKVK
                     TIIIPNPIKENLPYYNKTTSSKKFITACRLDKQKNLPLMIDAIGKLIHEGYECELDIY
                     GEGGLKTELESYINHNGLTEFVHLKEFTNKIHEKMQNAAGFVISSDYEGISNSMLEAL
                     AIGVPVIATDCPVGGARMYLGDRNEIGHLVECNNLDKLTDAMRRVLLDRESVVRKAQK
                     GIKLRKELTSKNISNIWYEYLNQFF"
     gene            2289..3689
                     /gene="wzy"
                     /locus_tag="L1V17_002754"
     CDS             2289..3689
                     /gene="wzy"
                     /locus_tag="L1V17_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy"
                     /protein_id="HBN1237455.1"
                     /translation="MFSLTLVAFTIFCAFSLNQNYWLNWLGILIYLYAICTWHWRKGD
                     SIFSLYTIFFTLFLLFSYGQCIMWAFGIGTDRGIGTTVVAYGTGIIPSESDMIMVKWY
                     SCISMFVFHIGALLFTRKTTLRKVSWYESGDADADRKFLFKIGCIISIIVVPIVFVSK
                     LLEVRIALVHGYNALYYGDYATQSGYLQIILYLFFPALICLLIGSNFSKVITRFVFII
                     FALYSLLGIMSGDRGSWLYSSIILIWAYTQYKGTFNYKKLIKWLILAVIGIYILNVIT
                     KARDGGGLSKLTLKDFTSVFDSDDSPLVDSFFEMGGTMSIITFFLISGNGIYPFANTY
                     LTSLLGSISTRMLSMFGIKFVLLADWFSQDYLGITWGTGFSMIAEAYVNGGYIGGIVY
                     IFIIGIVIGKILSNSIDNQDIENHPMKMFLAITTANIIMGFPRAASYLIVKNFVYGVL
                     IILLINFFLQQFNKRL"
     gene            3735..>5172
                     /locus_tag="L1V17_002755"
     CDS             3735..>5172
                     /locus_tag="L1V17_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis C-terminal
                     domain-containing protein"
                     /protein_id="HBN1237456.1"
                     /translation="MERTARLKKNTIWALVFQITSIVCGMILLRLILTKYGSEVNGMI
                     SSINQFLQIISFLQLGVGAVMQSTLYKPLAEKDNLMISQILASGGKFYRQIAYILLVY
                     VGLLLAVYYVLVPNEFGRSYTMAMIATLSINSFAQYYFGIVNTLLLSADQKIYITYIA
                     QTIAFISNTVACALLISLNTEILMVKLITAIIYLACPIYYRWYVDRNYNIKRNVSYDK
                     EPIPQKWNGVAQHVASVVLDSTDVVVLSIFSNLIYVSIYNVYNLVIYGVKQLFMAMTN
                     GVQALLGELWVRKEIEVLYKTFAWFEWIVHTLTVFIFGCTGILIVPFIQVYTRGVTDA
                     NYNQLSFAALLVTANALHCLRTPYHVMIKAAGKYKETQNSFIIASLLNLGLSLILVKP
                     LGLVGVALGSLISITYHTLWSANYNSKYLLKWPMKKFYKQLFVNILTVVLSFGATSQL
                     KMMSITYLDWIVLAIKCAVIVFICIILVN"
BASE COUNT         1837 a          609 c          939 g         1787 t
ORIGIN      
        1 gcaaatataa agataattgg aaaggaatta gtgctaagtt tgcattgaaa aacaaatggg
       61 tatttttaat ttatatttat aacaaattga taaagaggta ataataatgt cagttaagat
      121 tagtgtaatt gtaccttgtt ataatgttga aaaatatatt gatgagtgta taaatagttt
      181 gataaatcaa acattgaaag atattgagat tattttgtta aacgatggtt caacagataa
      241 tacgttggcg atattaaaga aatatgaaaa gcttgattct agaataaaag tttacgaaca
      301 taaaaatatg gggttagggc caactagaaa tcgagggatc aaaatagcta atggagaatt
      361 tttggctttt gtggattctg atgattttgt ttccaatact atgtttgaaa gtttatataa
      421 ttgtgcaatt gcagagaatg cggacattgc aattggagaa gtaggcattt tttctgatag
      481 agaaatagaa agagtaaaaa taagaaaaag tctaacgaac ttaaaaacaa ttgaattagc
      541 aacatataac aagaaagaat tttttaagca attctatttc aatcgtttat attcacataa
      601 tgcttgggat aagatatata gacgtagttt agtattagag tttaatttat catttggtga
      661 taacaaaata atttttgcag aagataattg gtttcaatta caagtattta tgacaaatac
      721 aagaatctgt ttcgtagata aattgtgtta ttattatcgc caacaaaata attctataat
      781 gcataagcca aaaagtaatt tggtttttag acatggaaat atgattgctg attatgaaaa
      841 gttgataagg caaaatggaa acaacataat agataaaaaa gcttgtatgt tggttgcatt
      901 tgatgtacta attatggaga tttttaatca aaaaaacgtt ggtggaacat gtgaagatta
      961 taagaatgca ttagtttctt tgaaacatca taaaatattg agagaaaata tttcaaatat
     1021 agttagaatg aaagcatatg aacttgaacc taatatgaga aagaagttag cccttgtgac
     1081 cattagtata atgtttaatt ttaaaatgta taaaacagcg tataatatgc tctggagaat
     1141 atataatcga taaagaggta ggaaatatga ggaaattgac ctttgtgata ggaattatgg
     1201 gaaaaggagg ggcagaacga gtaattgcga atttggcaaa taattttatt caagataact
     1261 gggaaattga tattataact atatatggga atcggcaaga ctatgaactg aatagaaaaa
     1321 tacaggtaca tccaataata tgtaaaagtt cgtttcgtgc atttagacct ttggaacgct
     1381 ttaaggaact taggaaaaaa ataagggaaa tacagcctga tctggttatt tcgttccttg
     1441 ctgatgtaaa tatccatgtc attatttcat tgttaggagt aaaacaaaaa ttaattgttt
     1501 ctgaacgaaa tgatccacaa cggaatccag aagaaccatg gattaggaaa attagagatt
     1561 ttctttataa aaatgtagat ggaattgttt ttcaaacacc agacgcaaaa aaatatttta
     1621 gtaagatcaa tgataaaaaa gtaaaaacaa ttataattcc caacccaata aaggaaaatt
     1681 taccttatta taataaaact acaagtagta aaaaatttat tactgcatgt agattggata
     1741 aacaaaaaaa tttgccctta atgattgatg caataggaaa acttattcat gaaggatatg
     1801 agtgtgaact ggatatttat ggagaagggg gattaaaaac cgagcttgaa agttatatca
     1861 accataatgg attaacagaa tttgttcatc taaaagaatt tacaaataaa atacatgaaa
     1921 agatgcaaaa tgcggcagga tttgtaattt cttctgatta tgaaggtata tctaattcta
     1981 tgttagaagc actggctatt ggagtgccag ttatcgctac agattgtcca gtaggtggcg
     2041 caagaatgta tttaggtgat agaaatgaaa taggtcatct tgttgaatgt aataatctag
     2101 ataagttaac agatgcaatg cgtagggtac ttttggatag agaaagtgtg gtaagaaaag
     2161 cgcaaaaagg aattaaacta agaaaagaac tgacatctaa aaatatttca aatatatggt
     2221 acgaatattt aaaccagttc ttttaaccaa aaggaggata ttgtgtgaaa gaaaaaataa
     2281 atatattgat gttttcgtta acgttagtcg cgtttacaat attttgcgct ttttcattaa
     2341 atcagaacta ttggctaaat tggcttggaa tattgattta cttatatgca atctgtacat
     2401 ggcattggag aaaaggagat tcaatatttt cattatacac gatttttttc actctttttt
     2461 tattatttag ttatgggcaa tgcattatgt gggcattcgg tattggaaca gatcgtggaa
     2521 tcggtacaac agtagtagct tatggtacgg ggattattcc tagtgaatca gatatgataa
     2581 tggtaaaatg gtattcttgt atttctatgt ttgtatttca cataggagca ctcttattta
     2641 cgagaaaaac cacactaaga aaagttagtt ggtatgaatc tggagatgct gatgccgata
     2701 gaaagttttt atttaaaata gggtgtatca tttctataat agtagtaccg atagtttttg
     2761 tttctaaatt actagaggta cgtatagcat tagtccatgg ttataatgca ttatattatg
     2821 gtgattatgc tacacaaagt ggatatttac aaattattct atatcttttt tttccagcct
     2881 taatatgttt attaattggt agcaactttt caaaagtaat aacgagattt gtttttatta
     2941 tttttgcttt atattcttta ttaggaatta tgtcaggaga cagaggaagt tggttgtata
     3001 gctctattat actcatatgg gcatacactc aatataaagg aacctttaat tataaaaaat
     3061 taataaagtg gcttatttta gctgttatag gaatatatat tctaaacgta ataacgaaag
     3121 cacgtgatgg tggaggacta agtaaactta ctttaaaaga ttttacatct gtatttgatt
     3181 cagatgattc tcctttagtt gattcttttt ttgaaatggg ggggactatg agtattataa
     3241 cttttttcct aataagtggt aatggaatat atccctttgc taatacttat ttgacctcac
     3301 tcttaggctc tatatcaaca agaatgctat caatgtttgg aataaagttt gttttattag
     3361 ctgattggtt ttctcaggat tatttaggaa tcacttgggg gactggattc tcaatgattg
     3421 cagaagccta tgtcaatggt ggatacattg ggggtatagt ctatattttt attattggta
     3481 tagtcatcgg taaaatcctt tctaatagta tagacaacca agatattgaa aatcatccta
     3541 tgaagatgtt tttggctata actacagcaa atattataat gggttttcct agagctgctt
     3601 catatttaat tgtgaaaaat tttgtgtatg gtgttttaat tatattgttg ataaactttt
     3661 tcctacagca atttaataaa cgtctttaat atttaagctt aataaaaaga taaaacaagt
     3721 caggagttgc aaaaatggaa agaactgctc ggctcaaaaa aaacactatt tgggctctgg
     3781 tgtttcaaat aacttctatt gtctgtggta tgatcttgct acgtttgata ttaacaaagt
     3841 acggatccga ggttaatgga atgattagct ctattaacca atttctacaa attatttctt
     3901 ttttacaatt aggagtaggc gctgtaatgc aatcaactct atacaaacca ctagcagaaa
     3961 aggataattt aatgataagt caaatcttag cttctggagg gaagttttat cggcaaattg
     4021 catatattct actagtatac gtgggtttgt tacttgcagt ctattatgtt ctcgttccta
     4081 atgaatttgg gagatcatat acaatggcaa tgattgcaac attaagtatt aattcatttg
     4141 ctcaatatta ttttggtatt gttaatactt tgttattaag tgctgaccag aaaatttata
     4201 ttacgtatat tgcacagaca atagcattta tttctaatac agttgcatgt gctttattaa
     4261 ttagtctgaa cacagagatc cttatggtaa aacttattac tgctataatt tatcttgctt
     4321 gtccaatata ttatagatgg tatgtggatc gaaactataa tataaagagg aatgtgtcat
     4381 atgataagga accgatccct caaaaatgga atggggttgc acaacacgta gcttctgttg
     4441 tactagatag tactgatgtt gtagtgttat ctatattttc taacctgata tatgtatcta
     4501 tatataatgt gtacaattta gtaatatacg gagtaaaaca gctattcatg gctatgacaa
     4561 atggcgttca ggccttacta ggggaacttt gggtcagaaa agaaatagaa gttctttaca
     4621 aaacatttgc atggttcgaa tggattgtac atactttgac agtttttatt tttggctgta
     4681 ccggtatact aatcgttcca tttattcaag tatatacaag aggagtaaca gatgctaatt
     4741 ataatcaatt atcattcgca gctttacttg taactgctaa cgcacttcac tgtctgcgta
     4801 caccttatca tgtaatgata aaagcagctg gtaaatataa agaaactcaa aatagtttta
     4861 taattgcttc tttgttaaat ttaggtttat cattaatttt ggttaaacca ctagggctag
     4921 ttggagtagc attaggatct ctaatttcaa tcacatatca tacactttgg agtgcaaatt
     4981 ataattcaaa atatttgctt aaatggccga tgaaaaaatt ctataaacag ttatttgtaa
     5041 acatcttaac tgtagttctt tcttttgggg cgacatcaca attgaaaatg atgtcaatca
     5101 catatttgga ttggattgtt ctcgcaatta aatgtgcagt tattgtattt atatgtataa
     5161 tcctagttaa tg
//
LOCUS       DAFLWC010000133         5054 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.138, whole genome shotgun sequence.
ACCESSION   DAFLWC010000133 DAFLWC010000000
VERSION     DAFLWC010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5054
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.138"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(82..1890)
                     /gene="pepF"
                     /locus_tag="L1V17_002756"
     CDS             complement(82..1890)
                     /gene="pepF"
                     /locus_tag="L1V17_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBN1237457.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(2066..3064)
                     /locus_tag="L1V17_002757"
     CDS             complement(2066..3064)
                     /locus_tag="L1V17_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HBN1237458.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(3290..3943)
                     /locus_tag="L1V17_002758"
     CDS             complement(3290..3943)
                     /locus_tag="L1V17_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HBN1237459.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            complement(4275..4673)
                     /gene="spxA"
                     /locus_tag="L1V17_002759"
     CDS             complement(4275..4673)
                     /gene="spxA"
                     /locus_tag="L1V17_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBN1237460.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT         1498 a         1039 c          767 g         1750 t
ORIGIN      
        1 taaaaaaata cgtcgactcc cttacaagag agccgacgta tttttttcgt ttctattcga
       61 gaaaatcaaa aatagaaagc cttataaacg atcgatcaat tcttctaatt catttagacg
      121 ttgttcaaac atcgacattg catcttcaat atatgcagcc tgtgtcatat caactcctgc
      181 ttttttcatt acttccacag gataatcgct gttacctgct tttaggtaag ccaagtagtt
      241 ctctagtgcc tctggttcct ggtttagtat tttcttcgcc agtgctgaag cagcagaaaa
      301 gccagtcgag tattggaaaa catagtaatt ataataaaaa tgcggtatcc gtgaccattc
      361 gaatttaatt tctgggtctt cttcgactgc tggaccataa tattttgcat tcaatttacc
      421 ataactatca cttaggtatt cactagtcaa tggcacacct ttttcatctt ccgtatgcat
      481 gaaatgctcg aattcagcga attgtgtctg gcggaaaact gttcctttaa acccatccaa
      541 gtaatggttg agtacataag cccgtacacg agggtctttt tctgtttcca ataaatactc
      601 cgttaggata ttttcattcg ttgtcgaagc aatttctgct aaaaagatgg agtagtcgcc
      661 gtacacataa ggctggttcg aacgagtgaa ataactatga acactatgtc ccatttcgtg
      721 gacaagcgta aatagctgat ccagcgtatc atgccaattc aataaaatat atggatttgt
      781 gtcatagctt cccgaagaat aagcaccgct tcgtttccct ttattttcga caacatcgat
      841 ccaacgttca gagaatgctt tttctacgat ggccatgtat tcttcaccca ttggtttcag
      901 tgcttctaaa gctttttctt ttgcttcttc gtacgtaaag gtaattggag cttcccctaa
      961 gaccggtgta taaagatcat acatgtgcag tttttccact tctaataaac gtttccgtaa
     1021 ttccatgtat cgatgtaaca aaggcaaatg cttgtttacc acgtctacca aagtatcgta
     1081 tacactttca ggaatatgat tattgctcaa agacgcttct ctggcagagc tgtaattacg
     1141 gactttcgct ttaaaattat gtccttttat atgtgtgcct aaagtagaag caaatgtatt
     1201 tctaaattgt tcgtaaacac tgtacaaccc cttaaatgct gcttcgcgca cccttcgatc
     1261 cgtgctttct agcaactgac catacacgcc atgagataat tggactattt caccattttc
     1321 tccttcaatc gttggaaaaa ctagatctgc attattcaaa acagcaaatg tatcacttga
     1381 agcatcaaag atttcacctg ctccagcaag aagagattcc tgctcagcag ataagacatg
     1441 ggctcgatta tctactattt gctggatata atggcgatag acttccaatt ttggttcttc
     1501 tttgaaatat tgccaaatct ggtcatctga caattgcaat atttctggtt caaaccagga
     1561 aacggcttca ctaactttcg aaaacagact gcttgctctt gcataaagcg cttggtaatc
     1621 tgtatttcca gtgtcttgat cgtttttaag gtgcgcatat acataaatga cttcagtttg
     1681 gcgataaacc ctcaatacga attcaatcgc atttaaaaat tgagaagcgc cttgatcaag
     1741 tgttcctttg tgtttttcag attgttttaa ctcttctgat aattccaaat atttctcatc
     1801 aaactcttgg tcgcttgaaa agatcttggt caagtcccaa gttaaatttt caggcaattc
     1861 ttctcgtttt ggcaactgct ttacttccat gaaatccact ccttttcttc ccttagctct
     1921 atctatcaaa atagatcata gtctaacatc cacatgtcac agcatctaac ttttctactc
     1981 attcatgtgt ctgcttccat caattttagc ataactaaat cttgttttac atagaaaacc
     2041 gattcctagc ctatttttat acttactatt ttttcaaaga agacaagtgt atgcattcgt
     2101 taaaaaactg ctgatagacc atctcttcat caatcatagg aaaaagccat tcccttttat
     2161 gttcttttat ttggcaaagc catgagttga aatcaggaac tttctggttt tccaaggctt
     2221 cttcgtacaa cattcgataa agaaaaacct gttcttgtaa ataaaagaaa aaccgacttt
     2281 tttgatagat ccacgatgat agatgcaaaa gatgtttatg acgcaagtag cattgttctt
     2341 gtatggatac tgtattcttt tgcttgtgaa taagttggcg tgtcagccat ttcttcccat
     2401 cttcactcac tttttctatt tttttcattt ggttcatttt aatttcgtta ctagtgaata
     2461 tttctttaag gtccctacta gaaaaagtcc agcagctact gcaaaaggaa atatgccctg
     2521 atacagtctc tgtaatatga tgatacaaat aaagcttttg tttcttgaga tcagctttcc
     2581 agcaatgcac tcctcttttt ctattatagt agcagcaact tttttctatc aatgagaatt
     2641 gcgattgtcc aagaaaagaa ttaccaagta tccaccatac ttggtaactg ttattcaaat
     2701 aattttgggt tctttcaata aatctctggt gagacagtct agaacattgg atttctattg
     2761 ctagattcgc caacaaaata tccggccttt gccgcaacct cggcaaatag gcttccaaaa
     2821 atactggttc tactgactgt cccagccaat ccatgaagca ttcctttaac tgtaagtgct
     2881 cttttgattc tctttcacta aagaccgaac agttatctga tttttgatgg gcaaaatgag
     2941 cacatttttt ctttcccttt ttcaaaatca ctctttttcg acagccacga caataatatt
     3001 tctttccttt ttctgcatgt ttagcaaaac agcacttatt atattcattc attgcaagca
     3061 gcatttttct ccctctgaac ttatttacgt ctaagaattt atttacacga aaaaagaggg
     3121 cgtgaaaaag ctattctgca tcaagtaata agaacagcta aacaaaaata gttcccaata
     3181 tttttcgttt ggttgggctt gttaccgcag atgcaagctt ttgaacacat ttatacgaaa
     3241 aaaagactgc gacacaattt ttgtcacagt ctcttactat aatgctgatt tatacaaaat
     3301 aaaatttcgt tcgctcgata gcattacgcg ccatcagaca ttgtccatat tcattcaatg
     3361 tttctggtgt acgatcgctc ttttcagcaa actccaaaat tcgagcaatc tgattctcta
     3421 catccgcttg gttgagattt tccatccaga agtgaacgac taggtaatag cgctcttcga
     3481 ataaatacaa atcagtccaa gcagactcta gttcgacatc tgttgcaagt tggatcactt
     3541 gttcaaaatc ttcaaaagca aaagttgctt gtctttcctg ttcttctagg gcgcttccag
     3601 ataattcttc ctccggatcg ctgccaataa tctgctgacg aagaaagtca ctcacatctt
     3661 ctgaatcaac agtagaatct tctgattgag aaatttcttc atccggaaga tttttactga
     3721 taaacagttc taatccgtct ccttttggca aaacttggaa agtgacagct tcgcttcctc
     3781 ggaactcctc ttcgatatca acttcttcca aaatactata aaagaaattt tcgatttctt
     3841 tgtgattgcc aagtaaatcc aaaaatgaaa cgccccgttc ctctaaatct tcatgaccaa
     3901 ttagtacacg gatcgtattt tcattaatat gttccatttc cattttgcta cacctcactt
     3961 tgccacaatg tttaatatag attcattgta gcgaaatcag cttaaatgta aagaaaaaaa
     4021 atctcgctgt taagcgaatt taataaaacc agcggatttt tcaacctttc aagctatctt
     4081 atttaactat aacatttttg gcagacgaat actatatagc cgacttttca gctaattttc
     4141 cctctctatt tttcgtgcaa tcatcatctt ctactacctt tttatacatc taatcaagaa
     4201 tactttttgt aaaaacaaaa aaacttggaa aaactatctt tgtaatagtc ttttccaagt
     4261 ttcgtattat ccttctataa tccagccatc aattgtgctt gacgtaattc taattgtcgt
     4321 acatcgcgcg gtaggaaccg acgaatttca tcttcattaa aaccaacttg cagacgttta
     4381 tcatcaatca tgattggacg gcgaagcaat ccaggattgt tttgcacaag ttccaataat
     4441 tcttgtaacg gcagatcatc taaatccatg ttcagttttt ggaatacttt ggaacgtgtc
     4501 gagatgattt cttctgttcc gtcttctgtc atttgtaaaa tcgcttttaa ttcagaactg
     4561 ttcaatggtt ctgaaaaaat attacgttca acaaatggaa tctgatgttc ttgcaaccac
     4621 gcacgagcct ttctgcagga agtacaactt ggggaagtat ataatgttaa caacgtgcac
     4681 cactcctttt cgtgataaga atcacttttt tgtaacagaa gatcataata atctcccatc
     4741 tgtttctatt atacataatc aacttttaaa tagctacctt tttttcataa tttttttaaa
     4801 aaaatgaaag ttatctaagg ttaatataca gtaaaaccag cattctcgct ttttttatca
     4861 tttaaaaatt agagttttca aatctaattc aaattttcta aacatatgaa acagcgtata
     4921 aaactgtact attattttat ctcaaaagct aaatgaaacc gatttcttaa gattttttat
     4981 gttttttatt tctttaatag taatgttttc tgtcatttta aataatactg ttctttatta
     5041 taacgcttat tttc
//
LOCUS       DAFLWC010000134         5025 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.139, whole genome shotgun sequence.
ACCESSION   DAFLWC010000134 DAFLWC010000000
VERSION     DAFLWC010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5025
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.139"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            283..522
                     /locus_tag="L1V17_002760"
     CDS             283..522
                     /locus_tag="L1V17_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237461.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(884..1144)
                     /locus_tag="L1V17_002761"
     CDS             complement(884..1144)
                     /locus_tag="L1V17_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237462.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1329..1826)
                     /locus_tag="L1V17_002762"
     CDS             complement(1329..1826)
                     /locus_tag="L1V17_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HBN1237463.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            complement(1956..2666)
                     /gene="budA"
                     /locus_tag="L1V17_002763"
     CDS             complement(1956..2666)
                     /gene="budA"
                     /locus_tag="L1V17_002763"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HBN1237464.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(2679..4343)
                     /gene="alsS"
                     /locus_tag="L1V17_002764"
     CDS             complement(2679..4343)
                     /gene="alsS"
                     /locus_tag="L1V17_002764"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HBN1237465.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(4548..5015)
                     /locus_tag="L1V17_002765"
     CDS             complement(4548..5015)
                     /locus_tag="L1V17_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237466.1"
                     /translation="MIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLFAWIVSVI
                     MIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVLRIAFYYT
                     LKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTMDL"
BASE COUNT         1529 a         1043 c          771 g         1682 t
ORIGIN      
        1 ctatcctcct agcaactatt taaataccca aaaaaattac ctctagataa tatcatacct
       61 acgttttcac ttataaattt tttcataaaa aaagcgttta gaggcataat cgttaataca
      121 gatggtaacc aatgtatctg gtttgaactg ggatatcacc ctctccatat atgtattact
      181 aagactaata gatactataa aagacttgat agttttgcat tgattttgcc taatactgag
      241 cataggtgta tgctaaacga tactataagg agtgtgtaca taatgaaaag aattctgttt
      301 atcagtttat caaatttatt gttacttact gcttgtggga cttctgcatc aaagaacata
      361 ccttcagata cgcaaatttc gaatagtatc gattcaacaa tttctacaaa tgagaaaaat
      421 tctccggtag aaacttccga tataaaagtt tctacctctg caaaaaacag ggtaaagaaa
      481 ctgtcagcac gtctccttta tttcaaacaa actctgaatt agcttcttca tcttcttcag
      541 caaataatga tgatagtttc gcgtttactc ctaactaaat gcaaccttta caaatgcttt
      601 acgataacaa gcctgagcta aatgatcctg atatcagttt tgcatttttt gaaatgattg
      661 gatcggatga tctttttaaa actactagtt tgtctatccg aaaataggac agttctggca
      721 gtataggttt ttatcgagtt tctccaccag gcctcgttac agagacagat tctctaggcg
      781 aaccttttga ataaatcaaa aatcatgaac aatcactgcc aactaaataa agtgccttca
      841 aaagcttggt cttctcgctt ttgaaggcac tttatttaaa tctttatgaa actaaagtat
      901 gttcatattt gttgctatag ttatatagat attctgttgt ttccaactca taaacgtgag
      961 tatattttgc cactactttt ccgcattttt ctaatatttc attgcgatcg acgtcatgat
     1021 attcgtctac gcagatcaca acacaatttt ctaatttact gattacttct ccaaccactt
     1081 tttgtttcaa gccaataggt tggcaaatat atttttttcc taaaatgata gtttcgttat
     1141 tcatatttca tccatcctta atgtttttcc attatttaaa atgataatac cattaaaata
     1201 tgattatgaa aatcaataac acttgtgatt ttataaaaaa ataaaaaaac cgaaaaacag
     1261 aaatgcccac tgtctttccg gctcttttta ttcttgattt ctcttctttt ttgtttcaat
     1321 agacgatttt agttattaat aaatgaaaaa gcatttatat taaaatttgc taataaaaga
     1381 tctacatatt tttctagaaa tgcttgatcg atttcatcat accctttcgt tactccgcaa
     1441 tcgatatcta aaacaccgat taaattacct tcttttacca ttggcactac gatttctgat
     1501 tgtgcggctg aatcgcagga aatgtaattt gcatgggttt tgacatcatc aacgatcaat
     1561 gtttcttgtt tttcagctga ttctccacaa actccttttc ccatcttgat acgtgtgcaa
     1621 gaaactcgcc cttggaacgg tcctaaaatc aattcattac catcgaataa ataatatcct
     1681 gcaaagacag tctcaggcaa agtctcattc aacaatgcag atgaatttgc taaatttgct
     1741 aaccagttat cttctgcttc taataatcct tgttgctgta ataataaaat ttcgtatgca
     1801 tcttttttct gtttttctgt ccacatgata aaaaccgctc ctttttgatc tatggagaag
     1861 attatagctc agtttttttg taaacgctag gtttcctcct caaaaaaacg agatacgtca
     1921 ggttaatcac cttgaacgca tctcgctgtc tttttctatt ctgcttgttg gatttctgct
     1981 gctaaatcag cataatcaat cgtttcgtga acaaaagtcg gatcatcaac tggaaaatgc
     2041 tgtacaaggg acgagatgcg gctaatctca acttttcctt cagccacttc aaaatccatt
     2101 acatgtccgc caaatgtatg tgtatcatcg ataaaatgca agtgaaatcc cgctgcagca
     2161 actccttgga ataattcagg cgtaaagaac ccgactaatg ttccttggac attgctttgt
     2221 tggaattctg gttgagactc tgaaattttt gctagtcttc tgtaaggttt ttcttgcttc
     2281 ggcatgatac ggatgtgcat atttttgaat aatccagtta tcttcactgc caaaaatagg
     2341 ttttccccgg cttctcttac taatatgtct tttttcaatt gttctccatc tgcagttttt
     2401 gagacagaaa aactagtatc tggcgtaaaa tctgtaattg ctgcataggg ggtaagttca
     2461 cttccatcta attgggcaac tgagccatct gatcttcctt gataagctac gccatctaaa
     2521 aagatgactt caccatcaag cccatgcaat gttcccaatc ccagagttcc tttttctaat
     2581 atatgagcaa tcgtttctgt tccatccatc aagccagcca tcaaagctcc taatgtcccg
     2641 tgctggtata agattttttc agtcatgtcg acacttcctt aatagaattg atctggtaag
     2701 attgtttctc ccaatttctc attatcacgg taatcaatcg gaatatcaat aattacgggt
     2761 ccttctgtcg caaatccttc ttctaaagct ttttctaatt cctctacact tgtagctcgg
     2821 attcctttag cgccaaaagc ttctgcatat ttcacaaaat caactggacc aaagtctaca
     2881 cctgacgccc gctgatattt cattttttct tggaactcta ccatattgta gtgtccatca
     2941 ttccaaatca aatgaacgat attcaatttt ttacgtaccg ccgtttctaa atcctgggca
     3001 gagaataaaa atcccccatc gccggaaact gatacgattt gtgtatttgg acgcaccaat
     3061 gcagcagaaa tcgcccatgg caatgcaaca ccaagcgttt gcataccatt actgaataac
     3121 aaatgacgag gttcataact tctaaagtgg cgtgccatcc aaatataatg actacctaca
     3181 tctacggtaa cagtcatatc atctgttact tttgactgaa gcgtgttaat aacttctaaa
     3241 ggatgcaaga tacctgcttc tccttttgat tgaacaatgt cccgctccgt taattctgct
     3301 tgaagagatg ctaaatattc ttttgcatct tctgacactt gttgaggctc taatgaacct
     3361 gtcaataaat caagagtggc tgagatatca ccgatcaatt ctctttcagg ctgcataaaa
     3421 ggatcgattt cagctggcgc ttcatcgatc acaatgatcc gcgcatcttt ttccgcattc
     3481 cagtttcttg cttcatattc gattggatca tagccaatag caataactag atcacttcgt
     3541 ttcaaaagca tatctcctgg ttggtttcta aataaaccca cacgaccaaa gaaatgcgct
     3601 tctaattcac gtgagatcac tccagctgct tggaatgtct ctacaacagg caatgctgtc
     3661 tttccaacta attgcctgat ggctaacgtt tctttttcac ttgatcctcg catacctact
     3721 aatagtaccg gtagttttgc ttctctaatg cgttcagcta ggtaacggat atcatctgca
     3781 gaagcagaac ctaatttagg atcgctcaat ggcttgatga cattcccttg gacaggtgca
     3841 tccactacat cttgcgggat actgataaag ctcgcgcctt tttttgaact cttagccata
     3901 cgataagcat tggcaatcac ttctgaaatt gtttctggat cttggatttc tgcactgtat
     3961 tttgtgattg gctggaacag tgctgcatta tccatgcttt gatgggtcaa cttcaataga
     4021 tcgcttcgtt ttacttgtcc ggcaattgct aaaactgggt caccttctgc tgtcgctgtt
     4081 accaaacctg tagctaagtt actagcacca ggaccacttg ttgcgataac tactcctggc
     4141 tctcctgtaa tacgtccgat tgcttgtgcc ataaatgcag cattttgttc gtgacgagtc
     4201 acgattaatt caggaccttg atcctctaat tcattaaata caccatcgat ttttgcacct
     4261 ggtataccga atacataatc aacatgatga ttaatcaaac tttctactac agatttcgaa
     4321 ccttgtttca ttttttcgtc cattgaacat cgtccttttt atgctttatt tttaattatt
     4381 agttagaaat aatcacaaat aattgataca gtttctaaac ctgtttcatt caaaagtata
     4441 gcacgtttta tttcatttgt ttagccatat gtttcaaaaa atgaaaaaga atgacagttt
     4501 ttacataaaa actgtcattc ttaattgaaa gtttcaattt ataaagtcta cagatccata
     4561 gttctcatca atttacgatt gttgaagtaa atcaaaccaa atacgataga aggacctagt
     4621 agaatacacc attggggctt tacgaaaaag aagagaaaca aacttgtcaa tagtaaaaaa
     4681 tctagtaaac tcacatacca ttttttcaac gtatagtaga acgctatccg tagaacttga
     4741 tttggtttcg acgctggatt tctcacctga aaataccagt agttgatgct aaaggaaact
     4801 gataaacaag caagtaaaac aaacaacgga atcaaccatt ttccataaga aaaacgtata
     4861 aaaaagaaac aatcaaaaat cattatcaca ctaactatcc aagcaaatag ccaataaaaa
     4921 aatcccttta gccaaaattg gcgaaacgtc tttatgaaca aacgtactgg tgaaaaactt
     4981 ttttcttttg ctaattcttc tgtcatacct atcatcacga tgcaa
//
LOCUS       DAFLWC010000135         4933 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.140, whole genome shotgun sequence.
ACCESSION   DAFLWC010000135 DAFLWC010000000
VERSION     DAFLWC010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4933
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.140"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            85..972
                     /locus_tag="L1V17_002766"
     CDS             85..972
                     /locus_tag="L1V17_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBN1237467.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="L1V17_002767"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="L1V17_002767"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBN1237468.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="L1V17_002768"
     CDS             2274..2720
                     /locus_tag="L1V17_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBN1237469.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2993..4345
                     /locus_tag="L1V17_002769"
     CDS             2993..4345
                     /locus_tag="L1V17_002769"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HBN1237470.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4516..4803
                     /locus_tag="L1V17_002770"
     CDS             4516..4803
                     /locus_tag="L1V17_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237471.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1695 a          813 c         1030 g         1395 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca accacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tattaaaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2881 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2941 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     3001 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     3061 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     3121 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3181 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3241 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3301 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3361 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3421 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3481 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3541 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3601 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3661 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3721 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3781 caaagtgaat gaatacatgc agacaagtaa tccagacatt tttgcagctg gagactctgc
     3841 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3901 tcgtcaaggt ttgcttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3961 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     4021 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     4081 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     4141 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4201 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4261 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagcagcgct
     4321 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4381 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4441 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4501 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4561 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4621 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4681 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4741 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4801 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4861 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4921 aacccctttt ttt
//
LOCUS       DAFLWC010000136         4658 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.142, whole genome shotgun sequence.
ACCESSION   DAFLWC010000136 DAFLWC010000000
VERSION     DAFLWC010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4658
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.142"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(93..1055)
                     /locus_tag="L1V17_002771"
     CDS             complement(93..1055)
                     /locus_tag="L1V17_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBN1237472.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1057..2496)
                     /locus_tag="L1V17_002772"
     CDS             complement(1057..2496)
                     /locus_tag="L1V17_002772"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HBN1237473.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2681..4627
                     /locus_tag="L1V17_002773"
     CDS             2681..4627
                     /locus_tag="L1V17_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HBN1237474.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKGTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
BASE COUNT         1474 a          797 c          770 g         1617 t
ORIGIN      
        1 gttgacaact cctttttgtt tacaaatcaa ttggatatct acaaattgta ttttctaacg
       61 aattttatag acattaaaaa attaatttaa cgttaaatac ttcctccaga aagtattgag
      121 attggtaaaa tataatcctt atttgtcttt tcgcctttaa tttttttcag aagaatatca
      181 acaataagac ttgcaatttc atcaattggt tgtcttattg ttgtcaattg tgggaaaaat
      241 ttctcaataa aagaggtacc atcgtatcca ataattttta aatcttctgg gatattaagt
      301 ttaagttgat gagcaatttt catagtgaga atggctgtta aatcatcaga aacaaaaata
      361 ccatctggtt tgtgatttat aatagttgac tttatttcca tttcacgacg gatagtagac
      421 agattattag gaattttgaa aatttttcca tttggatttt gaaaagaaaa acctagtgca
      481 cgtaattctg tgggagaatc cgtgttatca tttcctgtaa tcataatggt attttgacaa
      541 ccattttttt gtaaagtctt agctgcaagt tttccccctt caaagttatc tgaagaaaca
      601 atggaaacat taggagctaa atttctatca aaagcaacaa taggtgctct cacacgctca
      661 taatcagcaa ttccaagatt atggcttgat gagattatgc catcaacttg gttggcttca
      721 agcatttcaa tgtattctct ctctttagca ggatcatttt gactattgca aataatcgtt
      781 ttatatccat gtttaaataa ctctatttcg agatactcaa tgagttcaga gtaaaagata
      841 ttactaatat taggaaaaat aagaccaata agctgaggtg actttccttg aagtccacgt
      901 gctaaattat ttggtttata accaagagtt ttcatagctt catgaacttt ttgttttgtt
      961 ttttctgata aatatccctt attattaatg acgcgtgaaa cggttgttgg gctaactcca
     1021 gctaattcag cgacatcagt taattttgct accattttaa tattttaatt caaagtattt
     1081 tccagtaggt tcgcctgatt tgatttgaat accattttgg tgattttcag ggaatacacg
     1141 actagtaaac actttttctc ctttattaat aaaaatctca atgattgagt tatctacaaa
     1201 aatgttagca gttgtttctt tagtatcaat tgagcattca cgaatcgtac caaagtcagt
     1261 ggcatattga atgcctgctt tgctgcgatc taaaataatt tttccttctt tggtatctac
     1321 aatcaagcta agtccatttc ctttactatc agagaaaaga agtaactccg atttctgatt
     1381 tggaggaaaa gttagttcaa gctcataagt attatttgtt tctgcttttg ctgtaaattg
     1441 ttcagaacta gcacgtaatg atgtaatagc ttctactgga tattggtaaa gtttaccatc
     1501 ttttattgaa agttctttta caagactcat tgctccctga taatcatact tatcagttgg
     1561 ataatcgata tcaggtagtc caatccaact gacaatcaga gcacgaccat caggagtatt
     1621 gaatccttga gtcgcatacg cttcaaatcc ataatcaaga ttttgaattt ctgaagcgcc
     1681 cacaagtttt actttttcta tgtcaagcga ttgacagatc ttaaaagtat tcggatagat
     1741 attcccataa tttagctcag atttatccaa cccttgagga caataaatga gaacaggttt
     1801 tttgtctaca aatactagat ttggacactc aatcatgtat tctgaaccag tgccgccaaa
     1861 atcaaggttg ccaacttcct cccatgtttc cacgttattg tcatccgctt tgtaaagttt
     1921 gataaagcct gatttttcta aattttgtgc tccaacaatc gcatacaatt gtccttcata
     1981 attaaacatt tgtggatcac gaaaatgatc agttacatca gcaggtttat gaataagaac
     2041 attctcacct ttcgtaatgt tgtagtcttt atccatccat gctccgattt gaagtgtatc
     2101 acgttcccaa ttttcatttc gaacgtttcc tgtatagagt aagaatagat tcccctctat
     2161 ttcatatgca gaaccggaat aagcgccgtg gctatctcgt tttgtgtctg gaagaagttc
     2221 tgctcctgtt acatgaaaat gaactaaatc atctgattca ttgtgtaccc attctttcaa
     2281 cccatgagca gctccaaatg gccaattttg ataaaaaagc gtatattttc cgttaaaaaa
     2341 agaaaaacca ttaggatcgt ttaacaatcc tgttttaggt tcgatatgat agctagcacg
     2401 ccaaggtgat cgttttacat tatccttaat tttatccatc tcatctttag tccaatcaga
     2461 ataagcacga tatcgtattt ctcgaggtaa gttcatattt tactccttca atttatcttt
     2521 ttacaactag tatggtaaac gttttccgtt gaaaaatcaa tcatttcatt taaaaaaata
     2581 aactatatga caaacgtttg acatattttt aagatatgct aaaataaatt tgcatttcag
     2641 tgaaccgttt tcacgtaaaa ataaaaaagg agtgattcga atgaattaca gtaaagtagc
     2701 ttccgacgta atacaagcgg tcggaaaaga taaccttatt gcagctgcac actgcgctac
     2761 acgtcttcgt ctcgtactaa aagatgacac gaaagtgaat caaaaagctt tagacgaaaa
     2821 tccagatgtg aaaggcacat ttaaaattga tggacaatat caagtgatta tcggtgcagg
     2881 tgatgttaat ttcgtttatg acgaacttat caaaaaaact ggactttcgg aaatttcaac
     2941 agatgattta aaacaaattg ctagtaaaga taaaaaattc aaccccatta tggcattaat
     3001 taaattatta tcagatattt ttgttccaat tatacctgcc cttgttgcag gtggtttatt
     3061 aatggcatta caaaactttt taacagctgc tggacttttt ggaccaaaat caattgaaga
     3121 aatgtatcct gcgattgaag gtatttcctc aatgatccaa ctgatgtccg ctgcaccatt
     3181 catgttctta ccaattttag taggtatttc agctgctaaa cgttttggag caaaccaatt
     3241 tcttggtgct gcaattggta tgatcatgac aacaccagat cttggtggct caactgaata
     3301 ttggaatatt tttggttatc atgtttcaca aacaaactat gcttatcaag ttattccagt
     3361 tttagcagct gtttggatat tatctatatt agaaaaattc tttcataaaa aattgccatc
     3421 atctattgac tttacattca cgccattatt atcagtaatg attactggat ttttgacttt
     3481 cacagttatt ggccctgtaa tgttattgtt gtctaatgga attacagaca ttattgtttg
     3541 gctatataac actactggat ttattggaat gggtattttt ggaggaacat attcacttat
     3601 agtcatgact ggtttacatc aatcatttcc agctattgaa actcaattac tttcagcgtg
     3661 gacaaatggt atcggacatg gagactttat ctttgtagtt gcatctatgg caaacgttgc
     3721 tcaaggtgct gcaacatttg ccatttggtt cttaactaaa aattctaaga caaaaagtct
     3781 tgcttcctct gcgggtgtct cagcacttct tggaattaca gagcctgcct tgttcggagt
     3841 taacttaaaa taccgctttc cattcttttg tgctttaatt ggttcaggaa ttgctacagc
     3901 agtagcagga ttacttaaag tagttgctgt ttcacttggt tcagcaggtt tcttgggatt
     3961 tctttcaatt aatgcaacat ctattccatt ttacgtattg tgtgaattga ttagctttgt
     4021 agttgctttt gcaattactt acttctacgg taaaacaaaa gctgctggta tctttaaagc
     4081 agaagaaatt gctgaacaaa caccagttaa ttcttcaaaa gtagcaacaa cagatccaat
     4141 atctactgat gttgaatcaa cacaaacaaa agtttcatca gaaacaattg ttagtcccat
     4201 ttctggtaaa gtgattagtc tttcttcagt aaatgatcca gtcttttcat cagaagctat
     4261 gggaaaaggg attgccatta aaccaaatgg aaacacggtc cattctccag tagatggtac
     4321 tattcaactc acgtttgaaa ctggacatgc ttatggtatt aaatcaaata atggtgctga
     4381 agttctaatt catattggta ttgatactgt atcaatggga ggaaaaggat ttacacaaaa
     4441 agttactact aatcaaaaag ttagaaaagg cgatattctt ggagcatttg accgttcaat
     4501 gattgagaaa gaaggtcttg atgatacaac aatgattatt gtgaccaata cttcggatta
     4561 ttcagaagta aatatagtag ctgaaaatac agtcactgag ggtactgatt tacttgaaat
     4621 caaataaata tatttccctg agtaaagatg gaattttc
//
LOCUS       DAFLWC010000137         4620 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.143, whole genome shotgun sequence.
ACCESSION   DAFLWC010000137 DAFLWC010000000
VERSION     DAFLWC010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4620
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.143"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            153..959
                     /locus_tag="L1V17_002774"
     CDS             153..959
                     /locus_tag="L1V17_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-B"
                     /protein_id="HBN1237475.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGWR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            977..1684
                     /locus_tag="L1V17_002775"
     CDS             977..1684
                     /locus_tag="L1V17_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBN1237476.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGETFSFWLFLHTP
                     LTIIQRRGHEVKEFPEPNSDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKII
                     GQVFADKEPQALYKITNGSIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKC
                     KICYPLPESVDIQEENQ"
     gene            1681..2652
                     /locus_tag="L1V17_002776"
     CDS             1681..2652
                     /locus_tag="L1V17_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HBN1237477.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVSHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            2645..3673
                     /gene="vanB"
                     /locus_tag="L1V17_002777"
     CDS             2645..3673
                     /gene="vanB"
                     /locus_tag="L1V17_002777"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HBN1237478.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKAAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGIFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            3679..4287
                     /locus_tag="L1V17_002778"
     CDS             3679..4287
                     /locus_tag="L1V17_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HBN1237479.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(4353..4526)
                     /locus_tag="L1V17_002779"
     CDS             complement(4353..4526)
                     /locus_tag="L1V17_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237480.1"
                     /translation="MLPEKNGGLDFSKPPPAKYKMGVGKVCPTAVFFFSAAGQIEYYN
                     LQCITKDALTTFQ"
BASE COUNT         1300 a          972 c         1230 g         1118 t
ORIGIN      
        1 attttgaccg acaggtataa ccctgccggt ctttttttgc tgctacagga aaactacaga
       61 ctggctacag ggaaagtaca gatgcgcttg ccataataac aatcgtacca gccacaaatc
      121 gtagttttat tgcaaaggag gcattcgatc aaatggaaaa aagcaactat cattccaatg
      181 cggatcatca caaacggcat atgaaacaat ccgtggaaaa gcgggctttt ctatgtgcgt
      241 tcattatttc gttcacagtc tgcacgctgt ttttggggtg gagactggct tccgtattgg
      301 aggcaacaca gataccgccc atccctgcaa ctcatacagg cagcagcact gacgtagtgg
      361 agaatttgga ggaaaacgct cttgccaccg ccaaagaaca gggagatgaa caggaatgga
      421 gcctgatttt agtgaacagg cagaacccca tccccgcaca gtacgatgtg gagcttgagc
      481 aactatcaaa tggtgagcgg atagatattc ggatttctcc ctatcttcaa gatttgtttg
      541 atgccgcaag aactgatgga gtttacccga ttgtcgcatc cggataccga acaacagaaa
      601 aacagcaaga aattatggat gaaaaaattg ccgaatataa ggcgaaaggc tacacctctg
      661 cacaggctaa agcggaagca gaaacttggg tggccgtgcc gggaacgagc gagcatcagc
      721 ttggtcttgc tgtggatatc aatgcggacg gaattcattc aacaggcaac gaggtttata
      781 gatggctgga tgaaaacagc tatcgttttg gttttattcg tcgctaccca ccagacaaga
      841 cagagataac cggtgtgagc aacgagccgt ggcattaccg atatgttggc atcgaagctg
      901 ccacagagat gtacaaccaa ggggtttgcc ttgaggaata tttaaaacca gaaaaatgag
      961 aaaaggatgt tatgttatgg acagaaaaag attgacacag cgtttcccgt tcctgcttcc
     1021 aatgagacgg gcgcagagaa aaatgtgctt ttatgcggga atgagatttg acggctgtcg
     1081 ctatgcgcag acgatagggg aaaaatcgct ttcccatttg ctctttgaaa cggattgcgc
     1141 attatacaac cacaataccg gatttgacat gatataccag gaaaacaagg tgttcaactt
     1201 aaagctggca gcaaagacct taaacggctt attgataaga ccgggggaaa ccttttcttt
     1261 ctggttgttc ctgcatacgc cattgacaat tatccagcgc agaggtcacg aagtaaagga
     1321 gtttccagag ccaaacagtg acgagattaa aggggtggat gcaaccattt cagagggctg
     1381 gattgattta aaagtgcgaa acgataccga ctgcacctac caaatatggg tgaccttaga
     1441 tgatgagaaa atcatcggtc aggtgttcgc cgacaaagag ccccaagcat tatacaaaat
     1501 tacaaatggc agtatccagt atgtccgtga aagtggcggg atttatgaat atgcccaggt
     1561 taaacggatg caagttgcct taggtaccgg ggaaataata gattgcaagc tgctttatac
     1621 aaacaaatgc aaaatctgtt atcccctccc ggaaagtgtg gatattcagg aggagaacca
     1681 atgagaaaaa gtgtgggcat tactgttttt ggatgcgaac aggatgaggc aaatgctttc
     1741 cgcgctttat cgccggattt tcatattatc cctacgctga ttagcgatgc gatatcggca
     1801 gacaacgcaa aattggccgc tggcaatcaa tgcgttagcg taagccataa gtccgaggtt
     1861 tccgaggcga caattcttgc gctgagaaag gtcggggtaa aatacatttc tacccgcagc
     1921 atcggctgcg atcacattga tacgactgcc gccgagagaa tgggaatctc ggttggcacg
     1981 gttgcgtatt cgccggacag cgttgcggat tatgctttga tgctgatgct gatggccata
     2041 cggggtgcaa aacccaccat gcacgccgtg gcgcaacaag atttcagatt ggatcgtatc
     2101 cgggggaaag aactggggga tatgactgtg ggagttattg gaaccggcca tatcgggcaa
     2161 gcggtcgtca aaaggctgcg gggatttgga tgccatgtgc tggcctatga taacagccga
     2221 aaaatggatg cagattatgt ccagcttgat gagcttctaa aaaacagcga tattgttacg
     2281 ctccatgtgc cgctttgtgc ggatacccgc catctgatcg gtcagaagca aattggagag
     2341 atgaagcaag gcgcattttt aatcaacacc gggcgcggag cgcttgtcga taccggggcg
     2401 ctggtggagg cgttggaaag cggaaagctg ggtggtgcgg cactggatgt gttggagggc
     2461 gaggatcagt ttgtttatac cgattgctcg cagaaagtgc ttgaccatcc ctttttgtcg
     2521 cagcttttaa ggatgccgaa tgtgatcatc acaccccata cggcgtacta cactgagcgt
     2581 gtgctgcagg atactacaga aaaaacaatc aggaattgtc tcaattttga aaggagttta
     2641 cagcatgaat agaataaaag tcgcaatcat cttcggcggt tgctcggagg aacatgatgt
     2701 gtcggtaaaa gccgcaatag aaattgctgc gaacattgat acggaaaaat tcgatccgca
     2761 ctacatcgga attacaaaaa acggtgtatg gaagctatgc aagaagccat gtacggaatg
     2821 ggaagccgac agtctccccg ccatactctc cccggatagg aaaacgcatg ggctgcttgt
     2881 catgaaagaa agcgaatacg aaacacggcg tattgatgtg gctttcccgg ttttgcatgg
     2941 caaatgcggg gaggatggtg cgatacaggg gctgtttgta ttgtctggta tcccctatgt
     3001 gggctgtgat attcaaagct ccgcagcttg catggacaaa tcactggcct acattcttac
     3061 aaaaaatgcg ggcatcgccg ttcccgaatt tcaaatgatt gataaaggtg acaagccgga
     3121 ggcgggtgcg cttacctacc ctgtctttgt gaagccggca cggtcaggtt cgtcctttgg
     3181 cgtaaccaaa gtaaacggta cggaagaact taacgctgcg atagaagcgg caggacaata
     3241 tgatggaaaa atcttaattg agcaagcgat ttcgggctgt gaggtcgggt gtgcggtcat
     3301 ggggaacgag gatgatttga ttgtcggcga agtggatcaa atccggctga gccacggtat
     3361 cttccgcatc catcaggaaa acgagccgga aaaaggctca gaaaatgcga tgattacagt
     3421 tcccgcagac attccggtcg aggaacgaaa tcgggtgcag gaaacggcaa agaaagtata
     3481 tcgggtgctt ggatgcagag ggcttgcccg tgttgatctt tttttgcagg aggatggcgg
     3541 catcgttcta aatgaggtca ataccctgcc cggttttaca tcgtacagcc gctacccacg
     3601 tatgatggcc gccgcaggaa tcacgcttcc tgcactgatt gacagcctga ttacattggc
     3661 gttaaagagg tgataagtat ggaaaatggt tttttgtttt tagatgaaat gttgcatggc
     3721 gtccgttggg atgccaagta cgccacatgg gataacttca caggaaaacc ggtggatggg
     3781 tatgaggtga atcgcatcat cggcacaaag gccgtggcgt ttgctctgcg cgaggcacaa
     3841 atccatgcgg ctgcgcttgg ctatggcttg cttttatggg atggatatcg gccaagaact
     3901 gcggtggact gcttcctgcg ttgggcagcg caaccggagg acaatctcac aaaagaaaaa
     3961 ttttacccca atatagagcg agccgagttg attacaaagg gttatgtggc ctcacaatcc
     4021 agccatagcc gtggaagcgc aattgatctt acgctctacc acctggatac aggggaactt
     4081 gtttcaatgg gaagtaactt cgattttatg gacgaacggt cgcatcatac agcaaaaggg
     4141 ataggggatg cagaggcaca aaatcgaaga tgcttgcgta aaatcatgga aagcagcgga
     4201 tttcagtctt atcgctttga atggtggcac tataagttga ttgatgagcc ataccccgat
     4261 acctatttta attttgccgt ttcataatga aagtattggt tttgtatcag attttggatt
     4321 tgataaaatc tatgctggtc atggacaatc ttttactgga aagtggttaa agcatctttt
     4381 gtaatacatt gcaaattata gtattcaatc tgcccagcgg cagaaaagaa aaaaaccgct
     4441 gttgggcaga cctttcccac gcccattttg tattttgctg gcggcggttt tgagaaatca
     4501 aggccgccgt tcttttctgg cagcaaaagg tgtggcggcc cataggagga tgccgctatg
     4561 ctgttttgct attgccatgc tctaatccac ttccaccact caaaaaaagc cttgcccctc
//
LOCUS       DAFLWC010000138         4591 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.144, whole genome shotgun sequence.
ACCESSION   DAFLWC010000138 DAFLWC010000000
VERSION     DAFLWC010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4591
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.144"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            190..2859
                     /locus_tag="L1V17_002780"
     CDS             190..2859
                     /locus_tag="L1V17_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HBN1237481.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEVSFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEKPRNTHRRRRRK"
     gene            complement(2950..3570)
                     /locus_tag="L1V17_002781"
     CDS             complement(2950..3570)
                     /locus_tag="L1V17_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBN1237482.1"
                     /translation="MFLINATDEILSVNKVFYTVPAEKMSRVSSDINTITSRIGLTKA
                     MHMVLKYNQEDPPVPKTYEAIDLIIVDEIDRLKLQHLEQLRDIYDRNDLAMVLIGMPG
                     IEKRLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWADLGIDIKLEDFSDYEAITTI
                     IKITKGNFRLIHRLFAQIDRILRINQMDKITVEVVEAARDSLVIGI"
     gene            3684..4223
                     /locus_tag="L1V17_002782"
     CDS             3684..4223
                     /locus_tag="L1V17_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237483.1"
                     /translation="MKKLFSALFILLFGFIGIGTSGNIVKASTMVEQTSEMAKTFSQL
                     TPEEQSYFKSKGFSDKDTFYTQKIEPQDPKTRFSANVLRLTASTKKITNTQGRTEYII
                     TSPNSAMYRISTRLSLGSAKSYTQTVNLANSYGYGGGMYFTFTGKRQYYSVKLAMQVY
                     NTFGVGSVSCTAGGLTIGK"
     gene            4220..4558
                     /locus_tag="L1V17_002783"
     CDS             4220..4558
                     /locus_tag="L1V17_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic metallochaperone ArsD family protein"
                     /protein_id="HBN1237484.1"
                     /translation="MIISYYVLNRSDDEGLFVFQSLHEDTMLKEFYNRIKNKQIETNL
                     YFLSDSILPFISNPKILNLLQTKDLKSLPIIVIDEEIVKYGAYLSVEELEKLTNIGMS
                     IQEDNGVHGT"
BASE COUNT         1423 a          790 c          860 g         1518 t
ORIGIN      
        1 aaaaattttt aagggtggga cttttgattc ctaccctttt tttgcgttta tttttgttat
       61 acgaacaaat tatgaagtta tttattctaa attttatttt tttgtgaaaa ttagactctt
      121 tttaagcaga gaaaaacaag gatatgataa actgaataca acttcataga aatttggtgg
      181 aaaataaata tgaaaaaaaa tttaaagtca ttctttagag aaaacggacg ctacgcagca
      241 gctagtttcc tgattccgtt tttgatttta gcacttgttt atctaagtat cgggatctat
      301 cctggaagca gcagaagtat tttggcaagt gatgcctttt cacagttttc taattttcat
      361 gccagcttcc gaaatgttct tcttggaaag caaagtattt tttatacatg gaatgcttct
      421 ctaggattga attatttatc tttaatttct tactatctag gcgggatctt cacgccactg
      481 gtgttctttt ttccaaacca gatgatgcca gatgcactgt atgttctgac tttgcttaag
      541 gtcggctgtg ccggattggc tttttggttt cttgcacgta cgttcaagat tcctcgctgg
      601 gggcatgttg cacttagcgt cagttacgca ttgatctcat ttatcactgc acattcggag
      661 atcatcatgt ggctggatgc atttgtttat cttccattag tgattttggg gattcatcgt
      721 gttatggatc ttaaacggcc gaaactttta tttatcagtt atttactctt gtttttatcc
      781 agtttttata tgggttttat gattggcgta ttttctttct tatattttat cgcccgtcta
      841 ttgacaaact ggtcagaata taaaaaaacg attgttcctt atggtatcac ttctttactg
      901 gcaggcggcg cttcaatgat cattgtattg ccagcagtgc tggatcttcg gtcaaatggc
      961 gaggcactga gtcagatcac tacgttgaaa acagaagcga cttcttatct ggatctaatc
     1021 atgaaaaata tgattggtgt ttatgacacg acaaaatacg gatcgattcc gttcgtttac
     1081 gcaggtctgc taccattagt cctctgtctg ttttattttg ccagtcggaa agtaccgttg
     1141 aaaaataaat ttttgtacgg cagtcttttc gccatactta tcgcaagttt ctatcttgtt
     1201 ccattgaatt tgttctggca tggtatgcat gcaccgaata tgtttttatt ccgttatgcc
     1261 tatctgttct ctttcttagt gctcctgctt gcaggaaaag gatgggaaaa gatagaacaa
     1321 gacgatcgtg ggctgttgtt aggaatcatt ttggtcgtag ctgctctctt tgcggtggca
     1381 tggggcatca aacctgaagg aagctacacc tatgtgacga tgacttcctt tgtattgaca
     1441 gtggttttct tagggattta tgcttttgct gtgggatttt atcagcataa aaaactttca
     1501 ttcaatcatc tgagtatatt gttattattg atcatgtctg ctgaagcact ggtcaatacg
     1561 aacagtatga tccatggcat tcttgatgat tggaattatg cttcccgcag tttatatact
     1621 gatccttatc ctgacttgaa agctcttgta aatgaaacaa aaaaagattc cgactcgttt
     1681 taccgcttgg aaaatctgga tccagtatct gcaaacgatt cgatcaacta tggttacagt
     1741 ggtatcagtt tgttttcttc tataagaaat cgtaattctt cctcttacct ggataaatta
     1801 ggtttccgtt caagagggac aaatttgaat atccgttata acaataatac tttgctaatg
     1861 gatgggttta caggaatcaa atataacatt tctaaaaacg aaagcacgtt cagtaaatat
     1921 ggcttccgcc aagctggtca aagtggcgac tatacactgt atcagaatgt caatgcattg
     1981 ccactagcat ttactgcacc gttgtccgtt aatgatgttg agcagccagt gacagataat
     2041 ttgaccagtc agacaaactt gatcaataca ttgtctggtt taaatgaaca gtattttaca
     2101 ttctatacac ctactttgaa gaatcagttg aatacgacga tcacaaagac aacgactggc
     2161 gtcacttact cagaaacagc agataaccag ccaaaagagc tcacttggga agtccatgtg
     2221 cctgcaaata cacaagctta cttaagtttg ttcccaacca attttgcaca attagaaagt
     2281 tctagtgcga cgatcactgt caatggtaca tcgcgaaaaa cgcaaatcaa catttctggt
     2341 caatactatg atcttggcta ttatcctcaa gagacaacag tgacatttac tgcaagtttt
     2401 tatggaacga aagaagtaag tttcatggag cctaaagtcg ttggtctaga tgttgtagcc
     2461 tatcaagccg caatgaatca gatcaaagaa aaaggtgtcg aaatggaagc cactggcaga
     2521 aaagcttctg ggactgtaaa taccgctgaa gattccatgt tggtgacaac tattccttat
     2581 gacaaaggat ggaaagctaa aattgatggg aaaccagtca aggtcagcaa tttcaaagac
     2641 gcattcttga tgataaaagt tccagcaggt aaacatactg tcactttcag ttacttgcct
     2701 gaaggattta cgataggtgc aatccttttt gtcctatgta ttgcattgtt tattctttat
     2761 gtctggtacc ttgaccgcaa tcgccccttt tatggcacga ttgatccagc aatagaagaa
     2821 aaaccgcgaa atacacacag aagaagacga agaaaataaa gaaacgatgg aatctgtgtc
     2881 actcttctat ttaaatggca aaaatttcaa tctttaaatg acaaaaacca cctgattttt
     2941 ggtggttttt tatataccta tgactaaact atctcttgct gcttcgacaa cttctacagt
     3001 gatcttatcc atttgattga ttcttaaaat ccgatcaatc tgcgcaaata aacgatgaat
     3061 aagcctaaaa tttccttttg tgatcttaat gatagttgtg atagcctcat aatcagaaaa
     3121 atcttctagc ttgatatcaa ttcctaaatc tgcccatttg tattccaaaa tatgatgtgt
     3181 ttcgtcctta ctaaggttat caaattcatg tgcaaatcct atgcgagagt aaagctgcgg
     3241 ataacgagac aatctttttt caataccagg cataccgata agaaccattg ccagatcatt
     3301 tctatcgtaa atatctctta gctgttctaa atgctgaagc tttaaacgat caatttcatc
     3361 gacaataatt aagtcaattg cttcataggt tttaggcaca ggaggatctt cttgattgta
     3421 ttttagtacc atatgcattg ctttagtcag acctattcta ctagttattg tgttaatatc
     3481 cgaactgaca cgagacatct tttcagctgg tacagtataa aaaactttat ttacacttaa
     3541 tatttcatct gttgcattta tcaagaacaa gaaaaagtct gaatattcaa aaaaaataac
     3601 ggtgtacatt tttaaaagga gatgtataat cgagatttag aaagcgtttt cctcaaaatt
     3661 taatgaatta ggaagtgatt actatgaaaa aattatttag cgcacttttt attctgttat
     3721 ttggctttat tggtattggg acttctggaa atatagttaa agctagcacg atggttgaac
     3781 aaacaagtga aatggcaaaa acttttagtc aattaacacc agaagaacaa agttacttca
     3841 aatccaaagg atttagtgat aaagatactt tttacactca aaagatagag cctcaagatc
     3901 cgaaaacacg tttttctgca aatgtattgc ggttaaccgc atctactaaa aaaattacta
     3961 atacgcaggg gcggacagaa tatattataa caagtcccaa ttcggcgatg tatcgtattt
     4021 ctacacgctt gagtttaggt agtgcaaaat catatactca aacagtaaat ctagctaatt
     4081 cttatggtta tggtggagga atgtatttta catttactgg gaaaagacaa tattacagtg
     4141 taaaattagc tatgcaagtt tataatacat ttggtgtagg gtcagtctct tgcactgcgg
     4201 gaggattgac aataggaaaa tgataatttc ttactatgtc ttaaatagaa gtgatgatga
     4261 aggactcttc gtttttcaat cattacatga ggatacgatg ctaaaagagt tttataatcg
     4321 gattaagaat aaacagatag aaacaaattt atatttttta agtgactcta tcttgccttt
     4381 tattagcaac cctaaaattc ttaacttgtt gcagacaaaa gatttgaaaa gtttaccgat
     4441 tattgtcatt gatgaggaaa ttgtaaaata tggcgcttat ctaagcgtag aagaattaga
     4501 aaaattaact aacattggaa tgagtattca ggaggataat ggggtacatg gaacatagaa
     4561 tgaatatgca cagttgagaa cggaatttga c
//
LOCUS       DAFLWC010000139         4578 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.145, whole genome shotgun sequence.
ACCESSION   DAFLWC010000139 DAFLWC010000000
VERSION     DAFLWC010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4578
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.145"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(261..764)
                     /locus_tag="L1V17_002784"
     CDS             complement(261..764)
                     /locus_tag="L1V17_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBN1237485.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            1123..2148
                     /locus_tag="L1V17_002785"
     CDS             1123..2148
                     /locus_tag="L1V17_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBN1237486.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            2471..3349
                     /locus_tag="L1V17_002786"
                     /pseudo
     CDS             2471..3349
                     /locus_tag="L1V17_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
     gene            3825..3941
                     /locus_tag="L1V17_002787"
     CDS             3825..3941
                     /locus_tag="L1V17_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBN1237487.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
BASE COUNT         1511 a          734 c          830 g         1503 t
ORIGIN      
        1 aaattaagac ggaattcctt tctagattga gatattgact aggaagaatg ttaagatttt
       61 aagcctttaa gctaaaaaaa aacccttttt gttaaataag gggaatatag cctgtcagtt
      121 tcaaactgca agtcgtcctg ctgcaataat atagtagatt agagatgaaa atagattttt
      181 ttaaaccaat gactgaataa aaagaccgtc atagatacac attggaatgt gtctattacg
      241 gtcttttttt acgaacgatt ttattgaaga cggacagttc gggtcaaaaa taaaaaagct
      301 acgatcagaa ataagaataa aatgtatccc aaaataatgg ctagacggtc taacttattt
      361 gtcgatagat gtttgtttag aagttgatag gcccataaac ctatcagtcc tcctgttgta
      421 ttagttatca aatcagtgat gtccgctacg ccaataccga ataggaattg aatcaattct
      481 gccaagaagc ttacaaggaa aataatccct aattttttag aaaaagaaag tctcttgaaa
      541 ttgacattca aaagcacccc aaaaggaaaa aagacaatca agttataagt ggtctcacgt
      601 aataccgtcg tattttcaaa agaaaaagta gaaaaaggga cgagattgac attgctgtaa
      661 gaataagtga gaaattgtgg aagattaaat gatagcttga ataaaatcaa ccataataga
      721 aagaataaat aaatccctaa taaaaatttt gatacatacc gcatagacat ctcctccatt
      781 taaaaagtat accatcgaaa accgctgaaa aatcataaaa aagtatgaag tttaaggacc
      841 aacgtagtta tcgtacgaaa attagaagct tttttttgtt gggaatccgg tttctttaac
      901 aaagctaaga tagcgagttg cttggaaaag ttgctatctt ttttctgtca aaacgactcg
      961 gaatgttcgt tttttgttct aatttctcca agttgtttac tttttgatac taagtttatg
     1021 aaaaatcaag aaatagttgt tatactaggt aatgctgaca aacgggattg gcatttcatc
     1081 ttggttcagc tttttttcca attactagga aggagggata gattgttcaa gacttatttt
     1141 cgtttcaata aaatacaaga taatcctttt cgtatcatga atctgatgct acttatcttt
     1201 attgtattat ggttaggtta cataaatcat gattttttga tttcaagttt ttcatcatta
     1261 gggatcttta cttttttcta ttatcaaaac ataccgatga aatatttgct gaaacgtatg
     1321 tttctgatcg gttgcggact gttggttgct ttcgttttgg ggatcttatc gacttatgtt
     1381 ttatggcttg aaccatttgc cgtagctttg gttgcttttt ccagcagatt cgtgttgcga
     1441 ttattccata tttctaaacc aggtggcttg ttttttgcga tgctttctgc catgggaacg
     1501 agcatgcagc tgccaatcgc tcaattaccg atcgtctcac tttatttttt tatgggtgtc
     1561 gtttttgccc tgattgcggc agtgattaca aaattactgg attcacggcc tgagcagaca
     1621 attgaaaaag caactttaaa agaaagattt cacgaagagc ctttagtgat cattgattct
     1681 gttttctaca gcgctgcctt atttctttcc gtttatgtca gtcacggctt gaatctgcat
     1741 aatccttatt ggttgacctt gtcatgtgca tcgattttgc tagcagaaaa cttggatgcg
     1801 atgaagcatc gacaagtcca atatctgatt ggatcgatgg gtgggttatg tgtgtcggca
     1861 ttcttgtcat ttgtgccgtt tacgcagttg cagaccattt ttctgatcac ttttctatat
     1921 ggaatcgcac aatttctagt tgctagaaat tatgcagttg ctaatatttt tcttaatccg
     1981 atggcgttga tgctatctac acttattcgt ggagcatact tgatttcttt gatcgaatat
     2041 cgttttttag ggatcgtcat aggaagtttc atcggtttag gtgttgcgtg ggtaatgacg
     2101 gttggtttgc aacattattt aacggttgtt cgtcaaaaat tagaatagaa ggacaaatat
     2161 atgtgccaaa agaggttatg acaagatttt tgtcacaacc tctaattcaa ggtgttcaaa
     2221 agccagattc tcagcattaa gtcaaattca cacaaaaatg tggaaaggaa ctttcaaaaa
     2281 aattttatat ttattctatc aaaaaatttt gtttatgatg gtaactgaat aaactttcct
     2341 gagatggtca atgctttcct tgaaagtctt acagatattc tttcttcata gaaagtttaa
     2401 gttttatagt tagtgtacaa taaaagtatg tttataccat atggtgtccg gataatcagt
     2461 catttaaaca atgaggttca aagatatgaa aaggggaaat ttgatgaaga aaataagcaa
     2521 tgaaatccaa attctggcag aaactttaac tcttcccaaa gtcgttatag agcaaatgat
     2581 tgtacaagca aaaaacatcc ttgatgaggt gtttgagcaa tatagtcatg aactaatgga
     2641 tcctaataaa gcaaaggcga ctgcaaagaa aatagacaaa gtctatgaag aggaaccttt
     2701 tgcagcatta gctatttatc tatatgcagc ttctcaaagt tggaaaaaaa tttatcaacc
     2761 attgaagatt ccaagaacta tctatttggc aacaatgaat gcttttacta gatttattca
     2821 tgaacatttc caagtaacag gaagctatcg ctttgaccgt ggtttttgga tttggcatta
     2881 cactagtggc ttgatctttc ggattggtga attggagtac gaaatgacat attttccgaa
     2941 agggtacacg gatctaagat tagaaggaaa gcagtgcctt tctcttcata ttccttccga
     3001 tgcagattta tctcagaata agataagaga tagttacgaa agtgccattc gtttttttga
     3061 actttatttt cctgattacc attaccaagt gatgtacaca gatacttggt tactatcacc
     3121 caatcttact aaatagttga aaaaagagtc aaaaatctgt ctttttgcag ccgattatcg
     3181 attattatca gttgatgaac aggacgatag tggagtccct tggatctttg gacgagtaga
     3241 tgcccaaata catgattatc cagaaagtac gagtttacag cgacaagcaa aagagcaatt
     3301 gcttgcaggc gagcacattg gctctggctt aggtattctt acttcataag tttagtactt
     3361 cgaaatagtt taaaagagcg tgagacaaaa gtaaagaaca cttttgtctc acgctctaaa
     3421 cacgtataaa cggcggaagc agaagcaact ccttcggaaa taagctgaaa ttcacaaaaa
     3481 tttgaaaagc aattttcgtg aatttcttct tatttcttgg agttaaacgc ttctgtccca
     3541 gcctcttttt tagtgttcta tcgaacacac agtacgttca ataggtaaac tagctataac
     3601 aatagatatt aaagttaacg gacaagaggg ccttttttag gtagctaaaa cgtaataatg
     3661 aaaatttatt tccagagata ggagtcaatc agctagtctg atcgactgtt ttaacaagtt
     3721 gactttcatt ttaacttttg ataccattta aaacacaaat cgtaattgtt tcgatttgtg
     3781 ttttttagca tgactacaat caaagaagaa agtgggtcgt ccatatggaa aaaacagata
     3841 tctcaagtgc ataccgccgc ttgaaaagcc caaatatcaa aacacgaaaa cgtgcgctga
     3901 agatcatcaa agatgtgaaa cggaatagtg ggaaaaggta agaagaagga aacttaatta
     3961 aaaaaatagc cgaaaaacgt ttttcggcta ttttcaataa tcggtttttg tgtaaggttt
     4021 ccgaaagaac tgctgttgat tttccatttt taacatatga taaattggta gaatctttct
     4081 tttcaaattg ataccattcc ctaattccag ttatatagtt aactacagaa ccacaaagca
     4141 cgtacgttta taaaagtatt atctgtagtt atttttcaat tccctttcaa cctcttattt
     4201 tgaccagtag tattgatcac tttacctttt aacacctttg ttcgtttttg aaacattttt
     4261 agtcaagaat ggaaacgtaa ctacataatc aaaggttttg cgaaatattt catgaaatat
     4321 ttcatgtaga agcgagcaat acggttgcaa ataaccatta tcgtttaata agcagttacg
     4381 aaagctccca atatctctaa cgttcagctc actccatttc ttttcttcaa aaaaatcagt
     4441 gattcgtatc tctttctatt tgtcgaaaaa gttaacttta aaaagtaacg ccgaaaaaat
     4501 atgcaaaaaa ataaaaaagc agttactatt gctagaataa catcaaggaa taataagttt
     4561 tggttttcag ataatagt
//
LOCUS       DAFLWC010000140         4473 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.146, whole genome shotgun sequence.
ACCESSION   DAFLWC010000140 DAFLWC010000000
VERSION     DAFLWC010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4473
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.146"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            15..1955
                     /locus_tag="L1V17_002788"
     CDS             15..1955
                     /locus_tag="L1V17_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HBN1237488.1"
                     /translation="MKKIIAITSCPVGIAHTYMAAENLEKAGKAVGAEVKVETHGSIG
                     IENELTARDIEEAAGVIIAADTKIDKSRFGGKPLITVGVQEGIHHADELVRDILAGKA
                     PVYKSTEAIISSENKSESENLGKKIYKSLMNGVSYMVPFVVTGGLLIAISLTLGGTAT
                     PEGIKIPEGTIWATMNSIGSIAMGLMVPILSAFIAQSIADRPGLVPGFVGGMLAANGA
                     LYGSDANAGFLGGIITGFLAGFIALGIKKVRVPKALQSIMPIIVIPILGSLAVGFVFI
                     YVIGEPVALLFSSLTHFLAGMQGGSEIVLAMILGAMIAFDMGGPFNKVAFLFGSGLIA
                     EGNYSIMGPIAVAICIPPLALGLASLILKTKFTKTEREAGKASLAMGLFGITEGAIPF
                     ASTDPLRVIPSIVIGAMTGSVIAMLSGVTDHVAHGGPIVAVLGAVDHVAMFFVAVIAG
                     IAVTVLMLRILKPTLQQTAVAAANGVTVADLSETETSDVYTKTETFDSITDIMSDEAI
                     VLGETATTKDGVIEDLVQRLEKTAAITDKTRFKEVIYDREHESTTGIGMGIAIPHGKS
                     AYVLKPTVAFARSQSGVDWHSLDGKPAHMIFMIAVPENSQGDMHLKILQRLSRKLMDD
                     DFRQALMEAPDKTTVHQLLSEM"
     gene            2042..3964
                     /locus_tag="L1V17_002789"
     CDS             2042..3964
                     /locus_tag="L1V17_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBN1237489.1"
                     /translation="MNQRQQSLIYQLSENNNYITTKKLAEHFHVSERTIHSDLNTIET
                     WLRDKHLPLMFERKKGTGILLNGLPHEREQLKRALNEETQTEMDKKQLRQLLIFHLLV
                     AKDGFSLEELSEKLYVGKRTIRKELTELQSFFEYHHLQLVSKTKLGTFLKGDEQEKRQ
                     LLVKTLRNMQKEDPQSPSLKEFFAKDTLKVIQHTLQDVFYENHLEQPNGLASVEIHIY
                     FMLERMKQYQKVKLSKDENEVVEHTQAQKLSSQILAKLATIYPIEFSPDEINYLALRI
                     ANLFTNSQAATRFQKESSALADHLIEQVEQFLGYSLKEDQLLKQNLRSHLSSTYFRLH
                     YGLQISNPLTKNVFSTYTQLFLVLQLILEDYFEKENFYVPQEETAYLTIHFQAAIERH
                     KHQKSRRYQTVLVSEYSKAMATFLEARLNRELPELTIMDLVEYKPELKRQDFPSVDFI
                     LATLPFKHISIPVIEISPMITETDLAYLTKYMLEHVPIKKKKTFDLASFTHPFLIFPQ
                     LERTDPADILNFMGNVLVEHHYVEPEFIDSVLERDSHSSTRVAPFVTIPHGNPLYVKH
                     SMISIATMKEPVLWHGEQIRIVLLLAIKKNDLKHAEFKKIFSVIHYLEKQPEQMAQLM
                     QSNHPLEILTLLSSYE"
     gene            complement(4244..>4473)
                     /locus_tag="L1V17_002790"
     CDS             complement(4244..>4473)
                     /locus_tag="L1V17_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HBN1237490.1"
                     /translation="IDRDYFTQADLIITLCGDAKDKCPAVPNNHEHLHWDLKDPAQAV
                     GSEEEILTEFRKVREGIKRKVLDLNQRTSIV"
BASE COUNT         1478 a          765 c          927 g         1303 t
ORIGIN      
        1 aaggcggtag gaaaatgaaa aaaattattg caatcacatc ctgtccagtt ggtattgccc
       61 atacatacat ggcagcagaa aacttagaga aagcggggaa agcagttggc gccgaggtaa
      121 aagtcgaaac acatggttcc atcggtattg aaaatgaatt gactgcaaga gatatcgaag
      181 aagcagctgg tgtaatcatc gcagcagata ctaaaataga taaatcacga ttcggcggta
      241 aacctttgat aaccgtaggt gtgcaagaag gaatccacca tgcagatgag ttggtgagag
      301 atattttagc aggaaaagcg ccagtctata aaagtacgga ggcaattatt tcttccgaaa
      361 ataaaagtga atcagaaaat ttaggtaaaa aaatctataa gagtttgatg aatggcgttt
      421 cgtacatggt acctttcgta gttacaggag ggttattgat cgcgatttct ttaacattag
      481 gaggaacagc tacacctgaa gggatcaaga taccagaagg aacgatttgg gcaacgatga
      541 atagtatcgg aagtatcgct atggggttga tggttccaat tctatctgca tttattgcgc
      601 aaagtattgc agatcgtcca ggacttgttc ctggatttgt tggtgggatg ttagcggcaa
      661 acggagcatt atatggtagt gatgcgaatg cgggattctt aggcgggatc atcactggat
      721 ttttagcagg attcattgct ttaggaatca agaaagtgcg agtaccgaaa gctttacaat
      781 cgatcatgcc aattattgtt atcccaattt taggatcatt ggcagttggt tttgtgttta
      841 tctatgttat tggagaacca gtagctcttc tatttagttc attgactcac tttttagcag
      901 ggatgcaagg aggaagtgaa attgttctag ctatgatctt aggagcgatg attgcttttg
      961 atatgggggg gccgttcaat aaagtagcct ttttgttcgg atctggcttg attgcagaag
     1021 gcaattattc cattatgggg ccaattgctg tagctatctg tatccctcca ttagcattgg
     1081 ggctggcatc attgatttta aaaaccaaat ttacgaaaac agaacgagaa gctggtaagg
     1141 cgtccttagc aatgggactg tttgggatta cagaaggcgc tattccgttt gcttcaacag
     1201 atccactacg ggtgattcca agcattgtaa tcggggcaat gacaggaagt gtgatcgcga
     1261 tgctttcagg agtgacagat catgtagctc atggcggtcc gatcgtagcg gttttaggag
     1321 cagtggatca cgtagccatg ttttttgtag cagtgattgc tggtattgct gtaaccgtgc
     1381 taatgttaag aatccttaaa ccgacattac aacaaactgc ggttgctgca gcaaatggtg
     1441 tgacagtagc agatctatca gagactgaaa caagtgatgt ttatacgaaa actgaaactt
     1501 ttgattctat cacggatatt atgtcagatg aagcaatcgt tttaggtgaa acagcaacaa
     1561 caaaagacgg agtaatcgaa gatttagtcc aacgtttaga aaaaacagcg gcgatcacag
     1621 ataaaaccag atttaaagaa gtcatctatg atagagaaca tgaaagtaca acgggaatcg
     1681 gtatggggat tgctattcca catggaaaat cagcttatgt tcttaaacca acagtggcat
     1741 ttgccagaag tcaatctggg gtagattggc attctttaga tggaaaacct gcacatatga
     1801 tctttatgat tgctgtacct gaaaacagcc aaggtgatat gcacttgaaa atactgcaac
     1861 gtctatcacg taaattgatg gatgatgact tccgtcaagc actgatggaa gcgccagata
     1921 aaacaacagt tcaccaatta ttaagcgaaa tgtaacataa gatgaaaaat cgaccgtgat
     1981 gagacataat agatgtgtta tcatgatcga ttttttattt agaagggagt ttctgcacat
     2041 tatgaatcag cgtcagcaat ctttgatcta tcaattaagt gagaacaata attatataac
     2101 aacaaaaaag ctagcagagc atttccatgt gtcagaaaga acgattcata gcgatttgaa
     2161 taccattgaa acttggttga gagacaaaca tctgccttta atgtttgaaa gaaaaaaagg
     2221 tacaggtatc ttgttgaatg gtctgcctca cgaaagggaa caactgaaac gagcgcttaa
     2281 tgaagagact caaacagaaa tggataaaaa acagcttcgt cagttattga ttttccatct
     2341 gctagtagca aaagacggat ttagtcttga agaactttca gaaaaactat atgttggaaa
     2401 acgtacgatt cgtaaagaat tgacagagtt gcaaagcttt tttgagtatc accatttaca
     2461 gctagtatcc aaaacaaaac taggaacttt tcttaaaggc gatgaacaag aaaaaagaca
     2521 gttgcttgtt aagacattac gaaatatgca gaaagaagat ccacaaagtc cgtcgttgaa
     2581 agaattcttc gctaaagata cattaaaagt tatccaacat acattacaag atgtttttta
     2641 tgaaaaccat ttagaacagc cgaatggact ggctagtgtg gagattcaca tctactttat
     2701 gctcgagcga atgaaacagt accagaaagt gaaattaagt aaagacgaaa acgaagtcgt
     2761 ggaacacacc caagcacaaa agttaagtag tcaaatatta gcaaaactag ccaccatcta
     2821 tccaattgaa ttttctcctg atgaaatcaa ttatctggct ttgcgtatcg ccaatctttt
     2881 tacaaattca caagcagcca cacgttttca aaaggaatct agcgcacttg ctgatcattt
     2941 gatcgaacaa gtggaacagt ttctaggcta ttcattaaaa gaagatcagc tactaaaaca
     3001 aaatttaagg tctcatttat cttcaactta ttttcgactc cattatggtt tgcagatttc
     3061 taatccattg acgaaaaatg tgtttagtac gtacacacaa cttttcttag ttttacagtt
     3121 aattttagaa gattattttg aaaaggaaaa tttttatgtt ccacaagagg agacagctta
     3181 tttaacgatc catttccaag cagcgatcga gcgacacaaa catcagaaaa gtagaagata
     3241 tcaaacggtt ttagttagtg aatattcaaa agctatggct acttttctcg aagcacggct
     3301 gaacagagaa cttccagaat taacgattat ggatctagtt gaatataagc cagaattaaa
     3361 gagacaagat tttccctctg ttgattttat cttggctacg ttaccattta aacatataag
     3421 cattccagta atcgagatct caccaatgat cacagaaact gatctagcct atttgacaaa
     3481 atatatgctg gagcatgtgc ctatcaagaa gaaaaaaaca tttgatctag caagctttac
     3541 tcatccattt ctgatctttc ctcaacttga acggacagac ccagccgata ttttaaactt
     3601 tatgggaaac gtcttagtgg aacatcatta tgtggagccg gaattcatcg attctgtctt
     3661 ggaaagagac agtcactcca gtactagagt agcaccattt gtaacaatcc ctcacggtaa
     3721 tccgctgtat gtgaagcatt cgatgatttc tattgctaca atgaaagaac cagtcctatg
     3781 gcacggggaa cagatacgta tcgtactgct attagcaata aagaaaaatg atttgaaaca
     3841 tgcagagttc aaaaaaatat tttctgttat tcactatcta gaaaagcagc cagaacaaat
     3901 ggctcagttg atgcaatcca atcatccgct agaaatctta acgttgttat ctagttatga
     3961 ataagtagcg attaaaaaac tgcctttata tttataataa ttctatctat ttatttggaa
     4021 gtagaaaact aaatacaaaa aaagaggatg tggccaaagt tgtggcacat ccttttattt
     4081 tgagtttctt ataatttttt atagttgctt acgatgtctt gactactggt aaacggtgtt
     4141 caagagacaa tttgtcggca ataaggcaca attttgtaaa atatggaaag ctattttttt
     4201 aacattgttt cttagtgctt gaaaaatcat tttgaatact tctttatacg atcgatgtac
     4261 gttgatttaa gtctaaaact tttcttttga ttccttctct gacttttctg aattccgtta
     4321 atatttcttc ttcgctcccg acagcttgtg caggatcttt taggtcccag tgaaggtgtt
     4381 cgtgattgtt tggaacggca gggcacttgt ctttggcatc accacaaagt gtaatgatca
     4441 agtctgcctg agtaaagtaa tctctatcaa tca
//
LOCUS       DAFLWC010000141         4416 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.147, whole genome shotgun sequence.
ACCESSION   DAFLWC010000141 DAFLWC010000000
VERSION     DAFLWC010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4416
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.147"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            59..913
                     /locus_tag="L1V17_002791"
     CDS             59..913
                     /locus_tag="L1V17_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBN1237491.1"
                     /translation="MENSIYLVTEPNTQLKDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINDQKYFLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYY
                     LKEIGVGKNHLTFKVENLNSFKGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSAS
                     YLNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISI
                     KEYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRL
                     GLGIINGE"
     gene            1010..3259
                     /locus_tag="L1V17_002792"
     CDS             1010..3259
                     /locus_tag="L1V17_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBN1237492.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3262..>4416
                     /locus_tag="L1V17_002793"
     CDS             3262..>4416
                     /locus_tag="L1V17_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1237493.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTR"
BASE COUNT         1556 a          625 c          806 g         1429 t
ORIGIN      
        1 gtaataatat aaacataata aaacaaaaat tatccaaatc taacatagga gggtggatat
       61 ggaaaattct atatatttag taacagaacc taacactcag ctgaaagatt gttactttaa
      121 tttttgtggg tattcaaaaa cagaacctag acatagtttt ggaccagcta ttcgagaaca
      181 atacttaata cacatagtgc tagaaggtga aggctattat tcaattaatg atcaaaaata
      241 ttttctgaag aaaggccaag gatttgttat cccaccagga gtatctactt tttatcaagc
      301 agatgaaaaa aatccgtggt catatgtatg gttgggttta agtggcaatc ttgtagaata
      361 ctatctaaaa gaaattggtg ttggaaagaa tcatcttacc tttaaagtcg aaaatttaaa
      421 ttcatttaaa ggattaattt ttgaaacttt atcgtatgat caggacaatc tagtcagtga
      481 attgtccaga caaaaacaag tttataaatt tttagaactc ctcttaaatt cagctagtta
      541 tctgaacgaa gggataatta ctaaaaagat gaatcctttt gttcgtcaaa caattgaaat
      601 aatacgtgag aatgcgtatc aaaaattatc tgttaaagat attgctgtca gtctatcgat
      661 acacgaaaat tatttatcac gattgtttaa gaatgatatg ggaatatcaa taaaagagta
      721 tattagtgaa atcaaaattt ctattgcaaa cgatctgtta tcatcaactg aatattcaat
      781 ccagcaaatc agtgacaaga taggattctc aacagtacaa tctttttcta aagcctttaa
      841 gaaagcaaat ggtgtttcac cgggagtata tcgaaaacgt agattaggtc taggaatcat
      901 taatggtgaa taaactaaac atttgatttt gataaatatt cgttacttta aacgcttact
      961 atttatgtga gcgtttttta taatgcaata aagaaacgga ggagagctta tgtataagga
     1021 taatgaaatg aatattattt atcgatcaga aaaccaacaa tttcatttgt ttaatcagga
     1081 gataagttac atttttaaga tatcggaaga tggtaaatta ttgcatttat attatggtga
     1141 gaacttacca gataatgact atagtcatct aattgagatg catcatcggc ctatgacaac
     1201 ctatagaaat gaaaacgatt tgctatattc gttagagcac ttaaaacaag aatttcctga
     1261 atatggtaca acagatttta gacatcctgc tatttcatta ctacagaaaa atggctctcg
     1321 cttatcagat tttgtctatc aagggtacga agtggaagaa ggaaaaccta aactagaagg
     1381 tttacctgct acctatgttg ataataatga tgaaagcaaa acattgaaag tttatatttt
     1441 agattcagtt acaaatgttc aagtagaatt attatataca atttatagag attatcctgt
     1501 tattactcgt agcgcgcgag ttatgaataa aggaaaagat attcaaataa tcgagaatat
     1561 tagcagttta tcattggatt tacccgatgc aaattatgaa tggcaacaat tatctggtgc
     1621 ttggggtaga gaaagaacta ttaagtcgcg tactttacaa caaggaattc aatcaatcga
     1681 atctactcga ggtatttcaa gccatcagca taacccattt gttactttaa aaagaaaaaa
     1741 tactgatgaa aatcaaggag aagctattgg tgcagcacta gtttactcag gaaacttctt
     1801 aattcaagca gaagtagata catgggatgt tactagacta caagttggca tcaatccatt
     1861 tggatttaat tggaaactca atccaggaga aatatttaca gcaccagaag cgattctggt
     1921 ttattcaagt aagggtttaa atgccatgag tcaaactttt catcaactat ttagaaaacg
     1981 cttagctcgt ggtaagtggc gagaaaaaga ccgtcctgtc ttaattaata attgggaagc
     2041 aacatatttt gattttgacg aagaaaagtt ggtaaatatt gctaaaaaag catttgatgt
     2101 tggtattgaa ttatttgtat tagatgatgg ctggtttgga gaaagagaaa acgattgtgc
     2161 aggattagga gattggcatg taaatcctaa aagactacct agaggaatcg gcagcctttc
     2221 agaaaaaatt cgtagttttg gtatgaaatt tggtttatgg tttgaacctg aaatggtgaa
     2281 taaggatagt gagttatatc gcacacatcc gaattggatt atttctacac ctaatcgaaa
     2341 acctaatcat ggtaggaacc aatatgtatt aaattttggg ttagatgagg ttgttgaaaa
     2401 tattttcgat caaatgtgta aaatcattga tgaatcaaac ttagattaca ttaagtggga
     2461 tatgaatcgt ccattgactg atgtatttga cagtcacttg tcagcagatc aacaaggaga
     2521 agtattccac agatatgtac taggcgtata tcgcttatat gaaaaactta taacaaaata
     2581 tcctaacata ctatttgagt cttgttcatc aggtggtggg cgctttgatc ctggaatgct
     2641 tcactatgca cctcaagctt gggctagtga tgattcagat gcaattgaaa ggttaaaaat
     2701 tcaatatgga actagtatgc tgtatcctct ttcgtctatt ggtgctcatg tatcaattgt
     2761 tccaaatcat caaacaaacc gtataacacc tataaaaact agaggaaatg tagctttttt
     2821 tggtgcattt ggatatgagc ttgacttaaa tgaattaagt gaaggcgatt tgaggattgt
     2881 aaaagaacaa attgcctttt ataaaaaata tagaaccata attcataatg gtacttttta
     2941 tagactatta tcaccattcg atgatgataa tcaaaccgcg tggatggttg ttagtcatga
     3001 taagaaaacg gctattgttg ctcattataa aacattaaat gaggtaaatg ctccttaccg
     3061 ccgactgaaa ttaaaagggt tagataatga cggactttat aatgtaggac aaaatagttt
     3121 gcgatctgga atggaattga tgagagcagg actagtctgt tcagatgcat ctagtggaca
     3181 aataaatgat cagaatcgac gcccagaaac atttgatttt gattccaaga tttgggttat
     3241 aacacaggag gaaaagtaga gatgaataac caaaaaagct tacttcaaaa aggagcaatc
     3301 ttaagtattt cactaatgtt aacaagctct caagcaatta atggtgttat tccacaaatg
     3361 aaacagtctt tggggatatc acaaagtcaa agtgaacttt taggaactgc accaagtata
     3421 actgttattt tgtttatctt attatctagt tactttgcca aaagaatagg aatgaaaaag
     3481 acaataattt taggtttatt attagctggt ataggaggaa ttattccagt atttacagct
     3541 accttccaaa ccgttcttat tagtcgagta atattaggtg ccggtttagg agtatataat
     3601 tcattggctg tgacatatat cagctcttta tactctggca atactagagc aacgctatta
     3661 ggtattagaa attcaatgga agctttaggt cagacaatcc ttatttttct tgctggagtt
     3721 ttagtgaaca ttaattggac ggcttcgttt ttagtctatg caattgcgtt tcctgtagct
     3781 ctcttattcg cgctaaaagt tcctgaaatt agagatgaaa atagtgacat acctgaaaat
     3841 catgtaaaag aaaagatgaa tccaatggtt tttgccctag ttctatttgc aatcttactc
     3901 gtaatgaata gtattgctat ttctgtacga tttgcatcaa ttgcaactga aattaaaggg
     3961 gtaaacttta atgctagtaa ctatttagct ctaatgccta tcttaggaat actagcagga
     4021 tttatgtttg gaccaataaa taagtggata ggaaaaggaa ccctatactt gggaattata
     4081 ttctttataa tttcaaattt gttaattgct gtgtcaaacg gtaatatgac gttcctgcta
     4141 acgggtttat ttttatcaag tataacagga tcatggtgct tcccatttat ctttagtaac
     4201 ttagataaag tcactacaaa gaatacaatt aattttgcta cttcattgat ttttattggc
     4261 tgtaatattg gtaattttat agctcctatt gctatgcaat tagcacaatt tctaacaaga
     4321 agtacaaatt tgactgctcc attttttgta ttcgcaggaa tatttattgt gatcctattt
     4381 gtaacatttt ttgcgacaaa taaaaaaaat actaga
//
LOCUS       DAFLWC010000142         4350 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.148, whole genome shotgun sequence.
ACCESSION   DAFLWC010000142 DAFLWC010000000
VERSION     DAFLWC010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4350
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.148"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            23..904
                     /locus_tag="L1V17_002794"
     CDS             23..904
                     /locus_tag="L1V17_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBN1237494.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            917..2527
                     /locus_tag="L1V17_002795"
     CDS             917..2527
                     /locus_tag="L1V17_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HBN1237495.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(2604..3263)
                     /locus_tag="L1V17_002796"
     CDS             complement(2604..3263)
                     /locus_tag="L1V17_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBN1237496.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVALYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(3546..4211)
                     /locus_tag="L1V17_002797"
     CDS             complement(3546..4211)
                     /locus_tag="L1V17_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HBN1237497.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
BASE COUNT         1163 a          853 c          867 g         1467 t
ORIGIN      
        1 tagaaaaagg agtggggttt ttatggcaga aatcgtcaaa gtcacacatt tgaaaaagag
       61 ctttggtcgt ttcgaagctt taaaagatgt ctctttcacc gtacattcag gtgaagtcgt
      121 tggatttatc ggaccaaatg gttctggaaa atccacgacg attcggacac ttttagggat
      181 tataaaaaaa gacggcggaa cggcaacgat ttttgggcaa gatgtatggg aagatagttt
      241 atctatccat gaacgtcttt cttatgttcc aggcgatatc tctttgtggg gaaatttgac
      301 tggaggagcg atcatcgatc tcttcatgaa gcttcatgga aaagggagtg ctcaaaaaaa
      361 agatgaactg attcaacgtt tctctcttga tcctaagaaa aaagcaaaaa actattcaaa
      421 aggaaatcgc caaaaagtgg gcttgattgc tgctttggct gttgattcgg atctctattt
      481 atttgatgag cctacttctg gtttagatcc tttgatggaa acgattttcc aagaagaagt
      541 tgaaaaattg aaagaacagg gcaaatccat cctactttct tctcatattc tcagtgaagt
      601 cgagcgacta gcggataaag tcgtgatcat acgcgaagga acactcgatg aagaaggaac
      661 actcgatgaa ttgcgtcatt tgactcgttc gaccatcact atagaaacag aagcagagaa
      721 tagtcactta gcacaattga acggtgtcca tgactttgtg caaaaaggtc acctcgctca
      781 atttgctgct gataacgaag ctttcgatgt gattttagct gaagcgtcca aattaggtgt
      841 gaaaaaattt gaatctattc caccgactct tgaggattta ttcatgagac attatgaagg
      901 atgaggagga agcgaaatga ctgataaatt ttcacgctgg tccacccttt tttctcaaaa
      961 ccttagccgt gactggaaaa agatcctgat atggctagtc ggtgtcactg ctttttctgg
     1021 tggttttgtc cctgcgtttg aagaattgac ttccggacaa ggattagctg gattatacga
     1081 aaccttgcaa aacccggcaa tgattgcaat ggtcggacca actccagctt cgaatgctgc
     1141 tgagtatact ttaggagcga tgtatgcaaa tgaaatgttg cttttttgca gtttgtttgc
     1201 tgctgtgatc tctgttttac acgtggtgag ccaaacgaga aaaaaagaag aacttggtct
     1261 gattgaactt attcgttcct ttcgagtcgg acgtcaagca aactctttag ctgtcatcgc
     1321 tgaaagtatt ctgatcaatt tgcttttagc aatatcgatc agctgtacga tgattttttt
     1381 ccaagcggat tcgatcactg cagaaggtgc ttggcttttt gggctatctg taggtagtat
     1441 ggggattttg gggagtgccg ttgcactgtt tgctgcacaa ctgatgccaa gttcagccag
     1501 ttcgaatggt ctgtctttag cgtttttagg tggactttac cttctacgag caataacaga
     1561 tgtagctgat tcctcccttt cgatgtggaa tcctttaggc tggtcttatt tgacctatcc
     1621 atttacaact aacaactgga ttcctttgct ttatttgttt ttgttcagtc taatcttgat
     1681 aatcagttca tttgttttag aggaacatcg agatttgaac accggctata tccccgaacg
     1741 tgaaggaaaa ccgtatgcta aacgttctct tttatccttg cgtggtttat tattctatct
     1801 aaataaaggg atgacaatca gttggcttat cacttttggt ttgatggggg cggcatacgg
     1861 ctctatctac gggaatatgc aacagttttt agaaagtaac gacttaatga aacagatgtt
     1921 tatccaatct ggcgtctcaa ttgaaaaaaa ctttacaagc acgatcatgg tagtcttgat
     1981 ttgtctagct gctattttac caattgctag catcaatcgt ttatttacag aagaaaccca
     2041 cggacgtatg aatcagctgt tcgcaacaaa aatttctagg aaccaacttt attggaccaa
     2101 tatgttacta gctattctat ttgctatatt ggcaatcctg attagttctg gtgcactagg
     2161 gctttctgct ttggcttcga tgaaggatgc gaaagacatg gatctattga tgtttcttaa
     2221 agccgggttc aatttcctgc ctgccgtttt agtgtttatc ggaattagtg gctttctatt
     2281 cggatggctt cctcgaatcg gtaaacttgc ttatatctac ttagcttact cctttgcact
     2341 caattacttt ggcggaattt tggatttacc agaatggttt tccaaaacag ctgtccctag
     2401 ctgggttcca cggatgccaa acgattcttt tgatctttcc gtgttcctta cgttatcatg
     2461 tatcagcctt gcactgttcg tccttggttc tattggttat aggcgaagag acttactaga
     2521 aggataataa aaaagcatgt acaatttcat gctagcctcc aaatctgggt caaaaatcca
     2581 acatttggag gtcatttttt tatttacaag tcttctaact gctctttatc aatgatccag
     2641 acttctcgat tctttctttt tacataacca ttctcctcta ataatttaaa ttttctagat
     2701 aaagtttcgg gggtcgtacc gataaatgca gcaagttctt tcattttcat tggcaggaaa
     2761 aagtgatcct tccctgtcgc tttagctaag tcaagcagat agagagcgac tcgttcttct
     2821 actttttcca tcatcaaaaa agttgtctgc tgctgtactt ttgttaattt ctcaacgttg
     2881 attgctaaaa gtttcagact aagggcggga taatgcagta agagttccga gaaatctttt
     2941 tgtctcaata tgcaaatttc cgttttttct agtgcttcgc caaataaaga ctcatttgga
     3001 acgcctagca actggctctc tccctcatat ccgcccggct ctattactcg taaaagctgt
     3061 tcctttccgc tagcagataa ttgatacact ttcatactgc cggaggccac gatcactaat
     3121 tgaggttctc cattcggcgc aagaatctgt tctccttttt ccacatagtg atgtttgaca
     3181 agtgcgtgta ctttttcttg atcttgctgt actaagtgat tgaacaaagg aacaaatgaa
     3241 acacataaat gatcatgact cataatctct cctccttcta aacagctatt tctaataaag
     3301 aaacataact tcccttattc caactgataa ttttctttta tcatagcata aacgtcaagc
     3361 gaaccagata ccagcaaata gagtggattt ctttttgtcc cttgctttat tttccttctt
     3421 ttgagacctt aagtaattga ttcctatcaa ttttttaaat atttactttt tgaataatca
     3481 aaaacaaacc ttcactcgca agccgagagt aaggtttgtt tttcgcattg cttatttcgt
     3541 gttgtctatt gaaatttttc cgcacctagc ttttgatata gtggtgctag ttcttgtaag
     3601 gtttcagcgg ttatttgctc aacgtgttcg atttcttgcg gatagaagaa tagtttaccc
     3661 atttgaaagg ttcggtctct catcgctttt ttcaactctt cttgtttctt tgtatcggac
     3721 aaatagtcag acaaagctaa gtggtcgtca agttcatgtt ctggttgcgg ccatatgtaa
     3781 taatccttga tatcgactgt tttgctccac tctttcagta tcgcaagcaa ctggttatac
     3841 gctgcaatgc taccatatcg ttcttcgctt ttataatgtt ggtacatcaa atagatttgg
     3901 tattgttttt gattcaacaa aactgctaga caggcattct cgtcttgacg agattcgctt
     3961 cggtacgcgc tccaaaaatg actgcgtaaa ttccagccat tcgtccagct ttcgatttta
     4021 ggtttgctca tgccgtacat atcaggcaaa agtgcagctg tctggagctg aatctctttc
     4081 catttttgcc agtgttcttt atattctttc ttgatttgtt caatcttatc tgttggatgg
     4141 ctctctttga gctgtttgaa tgcgtagatt ggtcgatcaa acaactgata atctgatttt
     4201 ccaagttcca ttgtttcgcc tctttccgtt atcttttgta ttctacctga attttgcgat
     4261 atggacaaat agaggttgtg aaaaagctgt tctgcatcaa gtcataagaa cagccaaaca
     4321 aaaaactgcg atgagcatca ccgcagtttt
//
LOCUS       DAFLWC010000143         4315 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.149, whole genome shotgun sequence.
ACCESSION   DAFLWC010000143 DAFLWC010000000
VERSION     DAFLWC010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4315
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.149"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(68..553)
                     /locus_tag="L1V17_002798"
     CDS             complement(68..553)
                     /locus_tag="L1V17_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HBN1237498.1"
                     /translation="MVRRVFFSFHYADVTRAMVVRNSWTLRGTKEAGFVDKAEFEKVK
                     RNGDIAIKNWIDNQLIGTSVTVVLIGKETLDREYVKYEIQESYKRGNAILAVNIGKIK
                     DFNQMTTTSQSVIKIIGQKPDGEYLWFDEIIDGQYDYISDDGYNNLGTWIDSAAYKKG
                     K"
     gene            complement(555..1319)
                     /locus_tag="L1V17_002799"
                     /pseudo
     CDS             complement(555..1319)
                     /locus_tag="L1V17_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287699.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1489..2682)
                     /locus_tag="L1V17_002800"
     CDS             complement(1489..2682)
                     /locus_tag="L1V17_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1237499.1"
                     /translation="MSEKRRDSKNRVLRSGESQRKDGRYAYKYVDTFGKPQFVYSWKL
                     VPTDKTPAGKREDISLREKEKEIQKDLDDGIDTIGKKMTVCQLYAKQIRHRGNVKHNT
                     KLGRERLMRILEQDRLGSCPIDSVKLSDAKEWALRMKEKGLSYKTINNDKRSLKAAFY
                     TAIQDDCIRKNPFDFQLSDVLDDDTEPKVPLTPAQEESFLSFIQGDKVYQKHYDAIVI
                     LLGTGLRISELCGLTDKDLDFENRVIIVSHQLLRNTGVGYYIDEPKTQSGVRKIPMNE
                     EVYQAFQRVIKNRKGAKPFIIDGYANFLFLKQNGYPMTAVDYGGMFGRLVKKYNKSHE
                     EALPKTTTPHAMRHTFCTRLANAGMNPKALQYIMGHSNITMTLNYYAHATFDSARAEM
                     ERLAA"
     gene            complement(2766..2966)
                     /locus_tag="L1V17_002801"
     CDS             complement(2766..2966)
                     /locus_tag="L1V17_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBN1237500.1"
                     /translation="MNHDVPIWEKYTLTIEEASKYFRIGENKLRKLAEENPASGWVIM
                     NGNRIQIKRKQFEKIIDTLDTI"
     gene            complement(3390..3623)
                     /locus_tag="L1V17_002802"
     CDS             complement(3390..3623)
                     /locus_tag="L1V17_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1237501.1"
                     /translation="MKNPNYKGIELLPLSVIEAARAGDAGAVERVLQYYSGYMNKLCT
                     RTLYDENGYPHVCLDEAMKRRLEIKLIHAIVTN"
     gene            complement(3630..4061)
                     /locus_tag="L1V17_002803"
     CDS             complement(3630..4061)
                     /locus_tag="L1V17_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBN1237502.1"
                     /translation="MDAIPRDYEARCMFDAFCKTVLRNEAKSYLAEMKRRRDREVSLS
                     SLSQADLDKLCTVDHYPSDSFTFSSHGYDLHINNELVAEAFAALPSMEQSILILHCVL
                     DMADGEIGGLVGMSRSAVQRHRTNTLSELRKQLKALMPKGG"
BASE COUNT         1075 a         1069 c          838 g         1333 t
ORIGIN      
        1 tttaaagata cagggataag taagtaaaaa aataacatgt cattagatag tagacagttc
       61 caactcttta tttacctttt ttgtatgctg cactgtcaat ccaagttcct aaattgttgt
      121 atccatcatc acttatataa tcatattggc catcaataat ttcgtcaaac cacaaatatt
      181 ctccatctgg tttttgccca attattttaa ttactgattg actagtagtt gtcatctggt
      241 taaaatcttt tattttacct atattaacgg ccaaaatagc atttcctcgc ttataactct
      301 cctggatttc atatttaaca tattctcgat caagagtttc tttacctatc agcaccacag
      361 tcactgatgt tccaattaat tgattatcta tccagttttt tatagcaata tctccattac
      421 gtttaacttt ctcaaattca gccttatcta caaaaccagc ttcctttgtt cctcgcaaag
      481 tccagctgtt tctaactacc attgctcttg ttacatctgc ataatggaaa ctaaaaaaaa
      541 cccttctcac catattaatc ctcctgaata ctatttatta aactgacaat ttgttcaact
      601 tttttatcta cttctccttc agtatctaat ttttctagcg cttgaaattt actttttaag
      661 gaatcatcaa aataatcact gaaattctct tgaatcttat caaacaaaac cttacttgca
      721 cctttggtaa atccaatcgg aactactata ttttcatttt gaacagataa ttcaaattct
      781 tcaatcattc catctgctgt aactatttca cctgattcaa gtttgtttcc aaaaacaaaa
      841 atactaatcc cagactctgc aataatgttt tctcgatatc ttctccactc atgaggcata
      901 tcaaggggaa gtggtcttaa agaaagtacg tcttgtatgt tattttttct taaatttctt
      961 ctctgcttta gaactcctga aacaatacta ttaccaattc caagtccgta acctgatact
     1021 attctataac cggattcaga aagcctatat gctaatttct cgacaaattt taatcctttc
     1081 gattcagatg taaatggagt ataatcaaca gcacttcccg aaataaaaat agtttttctc
     1141 aaatactttt ttctaatact tttcaaaata tcagtaatct cagaataatc atctacttca
     1201 acaacgttta tcgaaaatct ggacaaatca ttgatttgta gtcttctttt tgtcagttca
     1261 taattatatc tctcttgatc aaaaaaatcc tcagaatcga caaaattttc ctttaaaatt
     1321 atatgggatt ttagattatc tttttagaag ttcttgaatg tcggtatagc ccgtgtttcc
     1381 gggcttttcc ggcatttttg atattgttag atacttacaa atgttcttat tacctctcac
     1441 catttccccc tcaaaagtag taaatggagt agtaaaaccg gccttgtgtc aggctgccag
     1501 ccgttccatt tctgcccttg cggaatcgaa tgtggcgtgt gcataatagt tcagcgtcat
     1561 ggtgatattg gaatgtccca taatgtactg caaggctttg gggttcattc ccgcattggc
     1621 taaccgggtg cagaatgtat gacgcatagc atggggcgtc gtcgttttcg gcaacgcttc
     1681 ttcatggctc ttgttgtact tcttcacaag cctgccaaac atcccgccat aatctaccgc
     1741 cgtcatggga tagccgttct gtttgagaaa caggaaattg gcatacccgt caataatgaa
     1801 cggctttgca cctttgcggt tttttatcac tcgctggaac gcctgataca cttcctcatt
     1861 catggggatt tttctgacgc cgctttgggt cttgggttcg tcaatatagt aaccgacgcc
     1921 ggtatttctc aaaagctggt ggctcacgat gattacccgg ttttcaaaat ccaaatcttt
     1981 gtccgtcagt ccgcacagtt ccgaaatgcg aagccctgtc cccagcagaa taacgattgc
     2041 gtcataatgc ttttggtaaa ccttatcacc ttgaataaag gacagaaaac tttcttcctg
     2101 tgctggtgta agaggcacct ttggttccgt atcgtcgtcc agaacgtcac taagctggaa
     2161 gtcaaacggg ttttttcgga tgcaatcgtc ctgtatggcg gtgtaaaaag ccgctttcag
     2221 ggaacgcttg tcgttattga tggtcttata agaaaggccc ttttctttca tccgaagcgc
     2281 ccattccttt gcgtcggaca gcttcacact gtcaatcggg cagctcccca gccgatcttg
     2341 ttccagaata cgcatcagcc gttcccggcc cagtttggtg ttgtgcttca cattgccccg
     2401 gtgcctgatc tgcttggcgt agagctggca gacggtcatt ttcttgccga tggtgtctat
     2461 cccgtcgtca aggtctttct ggatttcttt ctccttttcc cggagtgaaa tatcctcccg
     2521 tttacctgcc ggggtcttat ccgtaggcac taacttccat gagtaaacaa actgcggttt
     2581 tccaaaggta tcaacatatt tgtaagcata tcgtccgtct tttctctggc tctctccaga
     2641 ccgcaaaacg cgatttttgc tgtctcgtct tttttctgac atctcgtcat gctcctttcc
     2701 atgacggaaa gagccgcata tatgcttata aattattata acatatctgc ggcccttttt
     2761 cactattaga ttgtgtccaa agtgtcaatt attttctcaa actgcttgcg tttgatctgg
     2821 atgcggttgc cattcataat gacccagcca gaggccggat tttcctcggc cagcttacgc
     2881 aatttgtttt ctccgatacg gaaatattta gacgcttcct caatcgtcag cgtgtatttt
     2941 tcccaaatag gcacatcatg gttcataatg cagccccctt tcacaaattc aaaggtttgt
     3001 gtgatttagg ggcatagacg gacggctgct ggcacagctc cacgggactt tcacccccgc
     3061 gtggttctca cgcggcccta cccattgcct gcgacgcttt taacgctcgg actgtggcta
     3121 taagggagta tcatagtcct gcctgtacgt cgtcgcccgc aagccgccac gctcacattg
     3181 cggcgtggtg ttcctcgctc cgcttttccc gtagggaaaa gtatcatggc gcaccagccg
     3241 tccggctcgg cacagacaga atgtgtccgt atgccctatg atgcgccgcc gttatcttgc
     3301 gggcatattt atcaaggtgc gatcaggcca ccgggaaaac accgaaacgg ggaaagggta
     3361 agccgtttca tgctgccggg gccggttcgt cagttcgtga cgatagcgtg gatgagcttg
     3421 atttccagac ggcgcttcat ggcctcgtcc agacacacat gcggatagcc gttttcgtca
     3481 tagagcgtcc gggtacacag cttgttcatg taaccgctgt aatactgcaa aacgcgctct
     3541 acggctccgg catccccagc gcgggcggcc tcgatcaccg aaaggggcaa aagctcaatg
     3601 cccttgtagt tcgggttctt catccgcgtc taacctccct tcggcatcaa cgcctttagc
     3661 tgtttccgca gctccgataa ggtatttgtc ctgtgccgct gaacggcact ccgggacatt
     3721 cccacaaggc cgccgatctc accatctgcc atatccagaa cacagtgcag gattaaaata
     3781 ctctgctcca tgctgggcag cgcggcaaag gcttcggcaa caagctcatt gttgatatgt
     3841 aggtcatagc catgcgacga aaacgtaaag ctgtcgctgg ggtagtgatc tactgtacag
     3901 agcttgtcca aatctgcctg tgacaaagag cttagtgaca cttcacggtc acggcggcgc
     3961 ttcatttcag ccaagtagct tttggcctcg ttacgcagta ccgtcttgca aaaagcatcg
     4021 aacatgcacc gcgcttcata gtcgcggggg atagcatcca tcttctcacc ccctttctgt
     4081 gggggactta ggtggttctc tccctttccg ctaacaagac tttgacaagg ccgccagcta
     4141 cccgctaaat acctcctttt tgaaaatttc tcaaaaaatt tttttgggga cagccgggcc
     4201 gcaaaagacg acaaaaatcg cccggcaggt cgcaaaccta ccgggcgaga aaatgctttg
     4261 ctatgctgct gatttacatg gtatagtaca tactcataac cggaatagcc ctgtg
//
LOCUS       DAFLWC010000144         4282 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.150, whole genome shotgun sequence.
ACCESSION   DAFLWC010000144 DAFLWC010000000
VERSION     DAFLWC010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.150"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            336..1643
                     /locus_tag="L1V17_002804"
     CDS             336..1643
                     /locus_tag="L1V17_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBN1237503.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSVT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETARLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAE
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            1764..2963
                     /locus_tag="L1V17_002805"
     CDS             1764..2963
                     /locus_tag="L1V17_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBN1237504.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYSSTWTFAVI
                     LTYFVVLEIFYSTFYFLIPLVFFSIFAFSYFSEKRRLLNGLLFNIFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVFLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCIPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYWAQSRATLNPPILLMSGGQGADEKVPE
                     AMAMKQYAMEQGIPERDILVETNSTTTLENMRYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(2990..4258)
                     /locus_tag="L1V17_002806"
     CDS             complement(2990..4258)
                     /locus_tag="L1V17_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HBN1237505.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVRKGILFLPIVKRMKEKNKV"
BASE COUNT         1356 a          893 c          788 g         1245 t
ORIGIN      
        1 ttatcttcat aatttcctca attatttagc cccagtcttc aactattctt catgaaatgc
       61 tgataaacta agaaaaagaa taaaagaggt ggatcttatg catttgatta tgattttcag
      121 tttattaagt attatcagtt tatttgcttt cagcgcttcc cgcttattag atgcggaaac
      181 acagcctatt cctgtaaaag tacgtaaaaa cgaccgctaa ccttccataa cgtgcgttct
      241 tatcctaaag ttttttcaga aacattgaaa ctctctcccc tctctgataa aattttaatt
      301 tgtagcgaaa caaattaatt acaaggagat cggatatgtc cataaaaaaa acacgtctag
      361 tcctattatt ggctagtctc attctttgcc ttgcttcttt tctaccagct gttgctgtgc
      421 aagctgaaga tactttcaaa gtaaatgcaa aagcagcctt tgctgtagat gcgcaaagcg
      481 gtaagattct ttatgatcaa gatggagaaa aaaccatggg gatcgcttca atcacaaaaa
      541 tcatcggtct ttacatcgtc cttgatcaag taaaagaagg gaaactatca tgggatgata
      601 aagtttcaat ttcagattat gcagaaaatt tgagtgtcac cccagattta tcaaatgttc
      661 ctttgcataa agaaaacacc tacaccgtta aagaattatt cgactctgca atcatccagt
      721 cagccaacgc ttcaatggtt gccttggcag aaaaaatctc tggcagcgaa gcaaaattca
      781 ctgaacgaat gaaagaacaa ttgaaagatt ggggtatcaa agatgcaacg atcgttaatg
      841 catcaggact gaataactct tatcttggcg aaaaccgacc agaaggtact ggagaaaacg
      901 acgaaaatca aatgtctgct caagatgtgg ctatcgttgc ccgtcatttg atcttggatt
      961 ttccagaaat actggatgta tctagcacta cgacacaaat gtttggcgaa aacacgcaat
     1021 caccagtaga aatggtcaac tggaactgga tgctcccagg attcgtgaat tataaagaag
     1081 gcgtggacgg attaaaaact ggtacgactg aacttgcagg agcctgtttc gtcggtacga
     1141 tcactaaaaa cgatcaacga atcatcactg tcgtattgaa tgcagacggc catgcggaaa
     1201 acccaagtgc ccgtttcaat gaaacagctc gcttaatgga ttattgctac gacaattggt
     1261 cagaaaaaga gcttggaaaa gccaatgcaa gtatccctag tctaaaaacc attgatgtaa
     1321 aagacggaaa agaatcaaca gtgcccgttg tgcttaaaag tcctgtaaaa gtatgggtac
     1381 ggaacgatat ggatactgga aaattaacaa tcacaccaac tcttgacaaa aaacaagtca
     1441 ctgacaatga gatccaagca cctatggata aaggaacaaa aatcggtacc gcaacgatca
     1501 ccttggcaga agataaatta ggttatcttg aagacaacaa cgcgccatcc acagaaatca
     1561 tcacggataa aaccgtagaa aaagcaaata ttttcgttat tggctggcga cgcgtcgcag
     1621 aatttttcgg taacttgttt taattgaaca aaaagaaaaa agcatctttc catgtggaag
     1681 atgttttttt gctttttcta gtttaaataa cagctttttt catctatttt cgttatactg
     1741 tataagaaaa aggagttgaa tttatgaatc taaccagaga tctgattttt ttggttctct
     1801 atcttattgg ggtattctcc atcgtttatt ggcgaaaaca gaaaaaggat ccttccttgt
     1861 tcttttacag cagtacatgg acgtttgcgg taatcttgac ttattttgtc gtgttggaaa
     1921 ttttttattc gaccttttat tttttgattc ccttagtgtt tttcagtatc tttgcctttt
     1981 cctatttttc agaaaagcga aggctgttga atggtctttt attcaatatt ttcctcatta
     2041 gttttggtat ctacttgttt gtcttgctat acgaaacaca aaatattttt cttggcggac
     2101 tgattgcctt gatcacgatc ccgttactgc ttgtctttct attcggcatt tatggattga
     2161 tcgtttttct tttttggaac ggtgtcacag ttttacgtag agagtcgcat tcattagcta
     2221 atcttttaac gttgatacta gccatttttc ttacattgtt tcttgttttt gactttttct
     2281 tgttaaaata tttaccacaa tggataaatg ctttgttttt ctgcatccca ttgatcttga
     2341 tctatctatt tatcgtattc tacaactttt tgactgtctc attcttgtat cagttcaacc
     2401 gccctcgata caaccaagac ttcatcgttg tgttaggcgc cgggttgatc aatggagaaa
     2461 cagtttctcc tcttcttgcc aagcgaatca ataaggcgat tgctttttat tgggcacaaa
     2521 gccgtgcgac attaaatccg cctatcctat taatgtcggg tggacaggga gcagacgaaa
     2581 aagtaccaga agcaatggcg atgaaacaat atgccatgga acaaggaatt cctgaaagag
     2641 atattcttgt cgaaaccaat tcgacaacca ctttggagaa tatgcgctat tcaaaggaaa
     2701 tcatggatca gcaaatgaaa ggtccctatc gcgcgatctt cagttccaac aattaccaca
     2761 ttttcagagc tggtctctat gcacgacaag cgaaactgaa ggcaaatggc attggggcaa
     2821 aaacagcttt ctattacttg cctaacgcgt ttttaagaga atacatcgcc atcttgatga
     2881 tgaacaaaaa aagacatatg atcatttgcg gattgctttt cgcaggttcc gcattcttat
     2941 cactgatcac tttacttttc taaaaaaaca aggtgtgaca aaacatatgt cacaccttgt
     3001 ttttttcttt cattctctta actattggca aaaagagtat cccttttctg accgctactt
     3061 gctgagcaga ataaataccg ctgttgcctg aacacataaa gctgatcaag cagatcataa
     3121 agaagtatac tgccgcttgt gaaccgaaca attcgatccc catcacaaag caggcaatcg
     3181 gtgtatttgt cgcaccagaa aatactccga taaagcccaa tcctgcaaga aaaggaacag
     3241 aaacatggag caaaggcgct agtgctgcac caagcgttgc accaatttca aacaatggtg
     3301 tcacttctcc cccttgatat cccgcgccta aagacaaaac tgtgaagaat aacttcccaa
     3361 taaaatcata gacatgtgcc tgtccattaa atgattcctg cagtaatgga agactcaatc
     3421 cgagataacg ttgtgtttgc aaaatcaatg ctgcggctac aactacagcc ccacctatcg
     3481 tatttcgcca aacaggatga ggaatccatt gtgcatatcg cgcttttaaa aagacgatcg
     3541 aacggctgaa tacccaacca atcaaaccaa aagcaatccc agcaacaaaa actttgaaga
     3601 acagcaacat actccattca ggaatcacac ccatttggta atgtagatga gaaacaccat
     3661 agctttctgt cataaaattt gcaaacagtg cagcaaagaa gctagggaag atcgcttctg
     3721 ttcggacttt cccgattgcc aacacttcta atccaaataa tgttccagct aaaggtgtgc
     3781 caaatacaga actaaaaccc gcactgattc cactgataat caagatttcc cgttctgatt
     3841 tatccaatcg gaacaaacgt gctgtattat ctgctaacgc tccccccatt tggactgctg
     3901 ttccttcacg gccaacagat cctccaaata aatgggtagt tatggttcca aacagtgtaa
     3961 gtggaataag tcgcaacggg attttttctt ctccaccatt tccttgatcg atcactaagt
     4021 tgtttccacg actagaaaga ccgccgtgat acgcatagag ataagcaaaa agcgcaccac
     4081 taactggtag tagataaagg agccaaggat gtgatagtcg gatatctgtc acaactgtca
     4141 ggctatttaa gaaaaaagca gataagctcc ccatgaatat accgagaatc gctgtgatca
     4201 ccagccactt cagcatgtac actaaaatgc gtactggact cggtaattgt ttttccataa
     4261 aaaattcctc ctcaataaaa aa
//
LOCUS       DAFLWC010000145         4259 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.151, whole genome shotgun sequence.
ACCESSION   DAFLWC010000145 DAFLWC010000000
VERSION     DAFLWC010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4259
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.151"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            75..503
                     /locus_tag="L1V17_002807"
     CDS             75..503
                     /locus_tag="L1V17_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBN1237506.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFFI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
     gene            490..732
                     /locus_tag="L1V17_002808"
     CDS             490..732
                     /locus_tag="L1V17_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1237507.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(1032..1247)
                     /locus_tag="L1V17_002809"
     CDS             complement(1032..1247)
                     /locus_tag="L1V17_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237508.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            1354..1668
                     /locus_tag="L1V17_002810"
     CDS             1354..1668
                     /locus_tag="L1V17_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1237509.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            1772..2950
                     /locus_tag="L1V17_002811"
     CDS             1772..2950
                     /locus_tag="L1V17_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1237510.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            3353..3646
                     /locus_tag="L1V17_002812"
     CDS             3353..3646
                     /locus_tag="L1V17_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBN1237511.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
BASE COUNT         1455 a          642 c          821 g         1341 t
ORIGIN      
        1 tcctagattg tagtaataat ggaaagggat agaagtaaaa cgagttgaat gaattttttg
       61 agggggagaa tattatgggc gactcagagg aaacccacat tcaacatacg tttgacagtt
      121 tttgtaagaa agtagtctgc aatgaggcgt taaatattca aaagaagtac gctagatttc
      181 gccaacggca aatatcaatg gaaatattgg aacaaaaagg gttaggtaca gagttctatt
      241 atttggaacc aaatttgaat agtagtggta cttttattgt ccttggtatg aaaatcttta
      301 tttccaatga ggagttggca aatgcgattg cagcattacc tagtcaaaga caagaaatca
      361 tttttatgtc cttcttcatc ggtcttaatg atcgtgaaat tggcgatatt attgggaaaa
      421 gtctcggcag tgtttggtac caacgacaaa tggctttgga agagctagga aagtatttgg
      481 gtgtcaaata tgaagcaaaa taaacgatat ataccattca taccactaac gacaatcaaa
      541 gccgcagctt ctggtgattc aattgccatg tccatcgttc tgtcaaaata tcaaaattat
      601 atttcacggt tagccatgaa accagtttat gaagaagaaa aaggaatggt tatgtatgta
      661 gatgaatata tgcgtagaca actggaaaca aaattgattg agaagatact tgaatttgat
      721 acaactcgtt aaagtatttt ttccctttcc ttttcattct atggaagttt tttatcgggt
      781 caaaataaag gatttccata ggctgaaaat agcctagcgc tctttgacaa atgaatagca
      841 aatctatcag tacatgtaga ttttgattct ctagttacgc catgacaagg ttagctttta
      901 agcgacaaat tttaatatga gaatcgcgac tacgataatg atacttccgt aaccaaatcg
      961 gcccgccatt actgggggga ggtgagattc ctatgtgctt tggcaaaaca gctgatagat
     1021 cagaaaaact actatttcca tatttcgatt ttggttggca tatttttcat gccaaattct
     1081 gtgattttaa tagcatcggc aagatttaat ttttcttcag ctctctctcc acttttaagt
     1141 ttttttactg tactcaagtt gattcctgtt ccgaatgcta ttgcattagc cgtagatttt
     1201 tcaagaattt ctttaattat ttttatgtct gcaattcctt gtttcatatt aaaaattcct
     1261 cttttctagt ccgttttgat ggagtactgg agtgtttttt tacaatttta aggggtaccg
     1321 tggtggtcgt tttgattttg agagagaagg gtgatggagt tggaagttaa aacaaatgtt
     1381 aattctctgg aaatagagtt ctattcaatt ttacaaaaaa aactggaaga ttacacggaa
     1441 aaattgcttg cagtcagtca tttacctctg gtattaacaa atactgattt aaagcgacta
     1501 tttcagataa gtgatagtac actgaaccgt ttagtaaaac ttggtgagtt tcctccctgt
     1561 tggtacggga ttcgaggaca ctattttcgt gatgatgttt tagaatggat gagaaagagt
     1621 gattcgaatg actatcgaga aaaattgcga ctacttcgat ctttataagt tacattttct
     1681 ttctaagatg cggtacaatg atgacataga tagaaagatt tccaaagggt ttctgcttgt
     1741 tgggttcctt caaaatagga ggaatcaata aatggaaaaa acagatcgat tcaagaagca
     1801 aatcagttct actggtagga tcacatggta ctttcaagca tatcgaacaa caagacgtgg
     1861 ctttaattca aaacgtgagg cgcaactcgc ttatctggaa atggagaaac aacaaaggct
     1921 taagaaaaaa attgttgcaa gcaatgacaa gtttagtgtt gtaggtgagc aatggttcca
     1981 atattaccgt tcgttaaatg aacaaaagga aataacctat gataagcgag aggaacaatt
     2041 aaaaattatt gttcgatgga ttggtgataa aaagttgtct gatttgacac cagagtgcct
     2101 tcaagaattg ctttttacct taaaggaatg tggcgttaat ggaacaaatg ttggctatgc
     2161 caaaaatagt ttacaatcac ttattcaagt tctaaatatg atttttaaat attgtcaaag
     2221 aaagaatttg ataagtgaaa atccaatgaa gtctgtgaga atgccaaaat atcagttaac
     2281 ggtaactgat ttaaaagaag ccataaataa tattgaggac aagtttctta ctgtcgatga
     2341 attgagaact tttttgaatt atggcattgt tcatgaggaa ttaccgatgt ctgtactttt
     2401 ccatgttcta ttttacactg gctgccgagt cagcgaggcg cttgctctac agcctggaga
     2461 tatagatttc aaaagaaatg aaattctgtt ctataagcaa acggcagtta aaggtaagag
     2521 taaggatttt cgaattgaaa ctactaagac agttagttct gctagacgag ttctagtaac
     2581 tcctctagtt atggaaaagc tacaacagtt gattaaggct ttgggtgaga tgaggcaaca
     2641 ttacaggttt attatagaag aaacatattt gtttgtgtat cttgattcta gtaaacgtgg
     2701 tgttccttat cgtcgagagt atgtaaatga tcacgtcaaa cggtgcgtga atcgctcagg
     2761 aattaataag ccatttcata ctcatttagc tcgtcataca atggcaagct tagtagcgga
     2821 acactgtagc tgggaagtct tgaaagatcg cttaggccat actgaccaaa caacttcgaa
     2881 aatttatcgc cacttaacgt caaatgaaaa ggtaaaacct ctgattgctt ttagttcttt
     2941 agagagttaa aaaaacggtg aaagcactgg tattacagga ttcttgaaaa acgatttttt
     3001 aacaaattag tcaatatgta gtcagaggta ataaaaatcc ttttatatca atactttaac
     3061 gacttttcac aagtatcaaa gaaatccgtc gttaatcatt gttatcagac tgagaaagaa
     3121 cccttggtat tcaagggttc ttttttctta gcatgtaatt tgaacaccct gatccagttt
     3181 tttctttaat tattggtagg ggagaataat ggattagaat aaatctacct ataagtagta
     3241 gtaaaaaaaa gagcactatg ataatatctt tcttaagagt aaccgcttta ataaaaaatc
     3301 cagaatattc taacataaat ggagtattct tagaatcaaa aggagaaaga agatggttta
     3361 tacttatacg gagcaagaaa agatgaaagt tttagacaca ttcatgaatg atggaaaagt
     3421 aaaacaagta ccaagttcaa caaaaaagaa atacatccta ttgaaagaag tcttgaaacg
     3481 ctttgaccat ggagtgactt atacagaaac agaggttaat tcgatactgc tgaacgtatt
     3541 ttctagtggc gattatgtcg aacaaagacg ttatctaatc acatttggct ttttcaaaag
     3601 aagttcagac ggtcgggcat atcagatgat gggaattgaa aattagaagt tttaatttat
     3661 actcattgaa aaaagttcaa gtatgcgata ttggttctac accgcatact tgaacttttt
     3721 ttgtcatctg tatctataat acaaagccaa gaacgttatt caaaatatgg atagctatga
     3781 taaaagctaa tgagcgattc gcagttaaat aagcaatcgt cagtaaaatc gttccaggag
     3841 cgtacatgaa aaaatcaatt ggatgcgtta catgaataaa gataattctc ttttatttgt
     3901 acgaataaat accaaaacgt acctcctaaa attagatttt ggacagatgc cctttaaaaa
     3961 gataacaaga tttcgttctt gaaacaatat atatgctttt attccaatga ggttgtgaaa
     4021 acagtatttt gtcctgagcg ttagaaaatt gaaaatgggg aatagcaact cgtactttac
     4081 cattttttaa gtgaatacaa gatcagctaa ttgaacaccg tttattcgtg atgagggaca
     4141 caacactgca gtcgacacat ttctctttta tgttcaaaga taacaaatat ttaaaacaaa
     4201 gaaaaatagt agataatccc gtcctaactc ttttattctt ccctcatagc ttccaaatt
//
LOCUS       DAFLWC010000146         4246 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.152, whole genome shotgun sequence.
ACCESSION   DAFLWC010000146 DAFLWC010000000
VERSION     DAFLWC010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.152"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..536
                     /locus_tag="L1V17_002813"
     CDS             <1..536
                     /locus_tag="L1V17_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBN1237512.1"
                     /translation="DYPRINRNNTTAFKIFRAIINRCLRMIKLPPKIRHHKFDLYHGS
                     QWWALSKECLTELIQMYEQNQQDYLNFKIGMFAPDEKFFHTLFFNSSFKNKNVIGGPD
                     LPLELKNIEETTLQTSKLANIHIIDPSMNKWFDERDIDQIKESEKLFVRKVKSDYSDK
                     LLNRIDKEILKVGNIDE"
     gene            529..1956
                     /locus_tag="L1V17_002814"
     CDS             529..1956
                     /locus_tag="L1V17_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HBN1237513.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKEN"
     gene            1958..3028
                     /locus_tag="L1V17_002815"
     CDS             1958..3028
                     /locus_tag="L1V17_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237514.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            3015..>4246
                     /locus_tag="L1V17_002816"
     CDS             3015..>4246
                     /locus_tag="L1V17_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBN1237515.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKIT"
BASE COUNT         1451 a          519 c          672 g         1604 t
ORIGIN      
        1 atgattatcc tagaattaat aggaataaca caactgcatt taaaattttt agagctataa
       61 ttaatcgttg tctgaggatg attaaacttc ccccaaaaat tagacaccat aaatttgatt
      121 tgtatcatgg ttctcaatgg tgggctttgt cgaaagaatg cctaacagaa ttaatacaaa
      181 tgtatgaaca aaatcaacaa gactacctga attttaaaat aggtatgttt gccccagatg
      241 aaaaattttt tcatacactt ttttttaatt cctcgttcaa aaataaaaat gttattggag
      301 gaccagattt accacttgaa ttgaaaaata ttgaagaaac tactttacaa acttcgaaat
      361 tagcaaatat tcatattatt gatccttcca tgaacaaatg gtttgatgaa agggatatag
      421 atcaaataaa agaaagtgaa aaattatttg taagaaaagt taaatcggat tactctgata
      481 aactattaaa tagaattgat aaagaaattt tgaaagttgg aaatatagat gaatagaata
      541 gtacctgttt tagagaagag tttattaagt cgagatgcgt ttcgagtaat aaatttaatc
      601 atttgtctgc tttattttat gcctagtact tttaatgtaa ctaatatccc gatgaaaata
      661 gcttttgctt ggggtggaat tatagttttg tatgaggttt ttataaagaa aaattttttt
      721 aaaatgcgtt tttcttggct actgattgga gcaatgatta gttttatctt aactataatc
      781 attaacagag aaaatttttt aattccatct atttataatt ttggatattt gctgattact
      841 ttgatagtaa tttttcctgc agacttttca caaagtgaag aggaaaaaaa gaaaaaaatg
      901 gtgtatttta ataatgtttt cattatcata atttttttag ctgcgctaat atctatctat
      961 caatttattt ttttgatttc ttatcatgtc ccaacaggaa cgccaggatt acttgcaaga
     1021 caaggtttta ttgaacatcg gttatttggt gtctatacaa gtccaaatgt tggagctatg
     1081 tttggatata cttctattat tttaagttta attagtgtat taatttcaaa aataacaaaa
     1141 acgattcgtg ttttttatat gatgaatttt atcgtacaaa tattttatat tacactttct
     1201 tcgtctagag gtgcccaggt agtaatttgt tcttttttag tattatttct tttgttgttt
     1261 gccaattcaa aatttagaaa gagcattaga gaagtactac ctgtaaaaat caaatggatg
     1321 gtaagcatat tattagttct attggtatat ttttcttttg gtactaatta tgctaaggat
     1381 tttttagcaa caattcctgt atcgattgat agaaaagtag aagttataga gtcaaatgaa
     1441 tcagataaaa ctccacttcc agaaaaagaa gtaatattac agcattctag tgataactcc
     1501 gaaatttcag ctggtcgttt tacgatttgg aaagctgcgc ttaaagttat aagaccaact
     1561 ttgttatttg gttatggaga gaccgatttc tatgggaata gcgatgcaaa atttttgaaa
     1621 aaagtagatc ttgatactac agatgtgaat gaactaaaaa gagcacatgg aaacatgcat
     1681 aatggatttc ttcaagtact tgtatcaagt ggtataattg cttttatatg tatctatgct
     1741 ttctatgtgt taaatatctt tagtttactc aaaacatttt ttagaagtaa agtgaattat
     1801 gcgtttcttg gtattgtttt aatttttata ctatctattt ttatagatga aatggtggag
     1861 gctcatgtac ttttcaataa gcgcgatgtc atttcaattg ttttctggta ttatttggga
     1921 agcatttctt acttgtattt aaaaaaggag aattaatatg aagacagctt tcattgcttg
     1981 gactccttta catttgatta atatattaaa tgtttatcaa aatttttacc gagaatcaaa
     2041 aggagattta tttatttatt ctgaatttga aaacgctaga agatatagtg agcgtataaa
     2101 agaattaggg ctatttaatg atgttgtttt tgtgaatcac cggaaaatcg gttcttcctt
     2161 taaacgtaaa attaacttgt taactaacca taatcaattt ttctcggatg atttatccgt
     2221 ttatgatgaa atttttatac agggggaaaa ttatttcaca aaaatacttt tctccaatgt
     2281 ttacaaaaaa aatccagatg taaaactaaa ttatatagaa gatggtttgg gtacttattt
     2341 gaagaagagt atattttcaa caagtaaaaa cgttcaaaga gtttttaaaa tattaaataa
     2401 aaatagcatc ttcaaaaaaa aaattgacga ttattttgtc tattgtccgg aattgttact
     2461 ttatgatgta aaaaatataa aaaaaattcc caaaatagat gaaaacagta aattgatgaa
     2521 aaacatacaa tcaatctttg ggatagaaga agtttttgtc ggagataaat gtatcttttt
     2581 tgatcaacct ttattatctg atggttatgg catagatgaa acagatattt tcgctaaagt
     2641 aaatagtata ttttctggaa aaaaagaaac tttaattaag cttcatccta gagcaaggac
     2701 aaatcgttat ggtgaaaaaa acatattgaa ttccagttta ccgtttgaag tcttgctact
     2761 tgaaaatgac ttctcttcaa cacttttgat tagtcctata tctacaattt ctttttcacc
     2821 atctatgatg tttgaaaaga cgatcaactc tattatgttg gctaaattaa ttttaaatga
     2881 atatacagca ttatctgaag ataaaaaaga aacattgaca aatattgttc ttttctgtga
     2941 acattataac cgtctatcag aagaaaaaat tttactccca gaaaactggg cagaattaag
     3001 aaagttggta gagtatggga ttatttaaca cactttccaa gtcaaaatta gttaagtcca
     3061 gtttctggta tactataggg aattttttta ttaagggaat ttcattcata actattccta
     3121 tttttgtaaa tattactact caagcagaat atggtttgat taataatttc acttcatttg
     3181 tatcaatttt ttcgattctt gttgggctaa gcctaaattc ggcaattaat aatgcaagtt
     3241 ttgactataa agatgacata aatgaattta tgtcatcggt actttctcta gctacacttt
     3301 cgttaattgt gttcttatta atagggaaca tatatttttt gttttcaaat gctttttttg
     3361 atatgaacca acttgtattt aatttgatgt tattacaaag ttttgctagt tttgtaatta
     3421 gttatatcca gtcttatttt acgattaact ttaaccattt taaatatttg attttatctt
     3481 ttatatctac ttttttgaat attgcaatct ctgtagcttt gatgcagaca ttatattttg
     3541 atgataaata tgttggcaga gtagtcggcg gaacactgtc atttgtgttg ataggtttag
     3601 taatttattt aagaataatg ataaagggtg ctcatttttt tgataaaaaa cagtggagat
     3661 acgctttaaa aatctctttg ccgctaatcc cacattcctt agcaaatata gttttagcac
     3721 aattcgatag aattatgatt aattcttatt taggtcctgc tgcgggggga atatattcct
     3781 acattagtaa cataggtatt attctaagcg taatatggat gtctactaat aacgcctggg
     3841 ttccatggtt ctatggtgag atgagtaaaa ataatgaaaa aaaagtgaag aaagttagta
     3901 actattattt agtagtcttt actttgatta cgatgattgt aatggtagtt tcgattgatt
     3961 tagcaaaatt tatggctccg aaagactatt attctgggtt atctttagtg gttccgataa
     4021 ccttaggcta tttctttcag tttttatata gtttaccagt taatgctgaa ttttatgaga
     4081 aaaaaacatc gtttattgcg attggtacag tagcaagtgc tatagttaat atactattaa
     4141 acatgatttt catacctagg ttaggaataa ttgctgctgg atacacaacc gtatttacgt
     4201 attttttact ttttattttt cattataata tcgctaaaaa aattac
//
LOCUS       DAFLWC010000147         4170 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.153, whole genome shotgun sequence.
ACCESSION   DAFLWC010000147 DAFLWC010000000
VERSION     DAFLWC010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4170
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.153"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(652..942)
                     /locus_tag="L1V17_002817"
     CDS             complement(652..942)
                     /locus_tag="L1V17_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237516.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            1344..1580
                     /locus_tag="L1V17_002818"
     CDS             1344..1580
                     /locus_tag="L1V17_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237517.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            1587..3539
                     /locus_tag="L1V17_002819"
     CDS             1587..3539
                     /locus_tag="L1V17_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HBN1237518.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3611..4108)
                     /gene="dfrG"
                     /locus_tag="L1V17_002820"
     CDS             complement(3611..4108)
                     /gene="dfrG"
                     /locus_tag="L1V17_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HBN1237519.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
BASE COUNT         1425 a          730 c          711 g         1304 t
ORIGIN      
        1 taacttaaaa gttatctttt aaatacttaa ttgttaaata ccttatttga tgcaaaagaa
       61 atctacgata gtcaacaaaa aaattttcat tatatccaga aaaatttttc ttagttaagg
      121 acctatggat tgcagtaatg cagaattcgt cgaataaact gccaaagaca tacaatcata
      181 ttgcttttaa aattgacgaa caagatatag attcgtttgt ctcaaaaatc caaatgttag
      241 gtttaactgt cgaaccagga cgttctcgtg tgaaaggcga ggcttcttca atttactttt
      301 acgactatga taatcacctc ttcgagttac ataccggtac tctccaggaa cgtttaaaat
      361 cctacaattc cactacctga gactagtaat gactagtctc tttttatggc ctctgatccc
      421 cccattgagc gaatactaat agggcttcga attgatctgt tcaatcttta agcaatatcc
      481 ctcaaatgag tttggaaagt ttagtgattc atcacaaata cttaaataca tgtagttata
      541 tatagattga ggttcttgtg agcgtatgct cgtgtgggtt caaatcccat cgtctgcatc
      601 catctttcca aaacaagcgg ctaggacatt tttgtctcag ccgcttgttt tctagtttat
      661 tctttcatct tgtcggacct tttttcttgg gtatagactt ttctcatatt ctaccacaat
      721 tttgggtttc cctaacacat gataggatct cacaacaaat tgctttctat tattataata
      781 acctgtaacg actaacttca tcccttcgtc tacttcagct aggaagttca aactatggga
      841 agcaatcaaa caattgaccc catttaaact gaaacggatc aacggtctgg cactaacttg
      901 caaagtacgg atcttatcta ctgttccata ttttttctcc ataaccttca cctcaatacc
      961 attatacgaa catacattcc ctttgtaaag aagaaactct gttttatctt tttgactttt
     1021 tgtctattac ctttcttaaa atcatattgg cacttcctgc gaagatgaag gacatgtact
     1081 aaaaaaaaga ggcagcagta tagatttaag tagttcagtt ttggagtaca aaaagtgaaa
     1141 atgtaaacct aaatgagtat caaattgcaa ctgaatttga tactcgtttt ttattgttaa
     1201 atcaacgttt gttgttaatt tacaccacaa aatgtaagtt aaaatgtata taaaaatgcg
     1261 aacgtgaaat aattattgta ggaatgcaaa ttggtgtgtt aaaatggtta caatttacta
     1321 agcaaaaagg ggtgcatttt cctatgcaat ttcttgagcc aaaaaataag aacgctaagt
     1381 ctgtggattg ggaaatatca gagcaagtaa gggtgatagt taagcaatac gctgaatatg
     1441 cagagcgtac tgaaagcgaa gcagtggatg aattcttatt gaacatttta gacgataaga
     1501 agtttattga atggattgcc aacaagcgaa gtaataagcg gattgttgaa aaaatgggta
     1561 tcaaagatag agtgggttga tagacaatga ccaagcttaa aagattagcc acgaaggaag
     1621 atgaaattgt agatgttaaa attccgattt caaacgaaga attaaaagat agggctaaac
     1681 aatatgattt attaactcca aaacgatttg caacaaggta taacaaaatg ttgttcttgc
     1741 caacgtcttt taaatggaac ggttctgaat atcccattca atataattac tgcatcaatc
     1801 cgttttgttg taattttggg aaagaacagc acaaattcaa agatgtaaaa gggaaaccaa
     1861 gtcgatataa aatgactggt agttccaaag ataaaggtca taaaggtatg tactgcaatg
     1921 acaatcctat tggcagaggt gtatcgcaaa actgtacagt aaccccttta tctaattggt
     1981 ctgttgttga agaaattaaa cgccttatag aaatcaatag catccaagat gttgagccag
     2041 attatcaatt tcataaagaa ggctgctcgg aagaagaatc aaccccattc aatgagccga
     2101 agcaatttta caaaaggggg aaaagtaggg gcaaatctca acgctatcaa tgtaaggcgt
     2161 gtaagaagtt cactaatgtt ctaccaaaaa gagaagaaac cactacttat caccaacaaa
     2221 agaacaccat tcttccaatg ttcgctaaga tggttgttgg aagggtttca gtcagtcgta
     2281 cttgtgatat tttaggaatt ggagttggaa cctactatca taagctggag tggctgtata
     2341 ggcgttgttt ggagttttta gaacgatatg agacacaacc ccttcaaaca aagaaattta
     2401 acgagatgtg gcttaatacg gacaagatgc actactacct aaataacgtc cgtaagaaag
     2461 gacaaggttc aaagaaatat acggggtttg aagaccttaa tatgcaaacg tatatagttg
     2521 tatctgctga ggtcttatca agatatgtgt tccgttctga tgttgcctat gattggaata
     2581 tttcaatgga tgaattaaat gaagatacaa gaaaattcaa agaagaccat ctcaatactt
     2641 ttagtcgtaa aaatgatagg ttagattggt cttattatcc acaagaacca tccgctaacg
     2701 atagcgaaaa taggaatgct tatcttcacg aattagggaa aattactaat aggagtagat
     2761 ttgtcgatgg tttaaatgtt gatgctcctt atactacaac tgctcactat tggttaatta
     2821 aacaaatggt taatgccgac gaatggcgaa tgattagtga tgatgacttc tctattagaa
     2881 acgcctttta tagagtattc acgaaagaat taaggttgag cgatgcacat cattttattt
     2941 gccaagttaa caagacgaaa agcagaaaac aatgcttaaa agaattcgga caagcaaaag
     3001 cagaactgct cgattgggga gatatcagag gattcaaaac aaagtttcta cggactttgg
     3061 catctcatta tctaactgaa ttactaacaa gtcatcaatt ccacgaagag gctattagta
     3121 aagatggaga aagatatcgc aaatatgccg ataaccctat caaacatcca ttagccacta
     3181 aggataaagg attttattca gttgattgta gaacggattt atctgctctg gaaccaaacg
     3241 aaatcgcaaa gatgctatta aatgttaatg accattcgac caatagcttt attcaacaga
     3301 taagacgtta tatatcatct cttgaaagac cattaacaac agctcgtggt gataagaaga
     3361 gctatattta cgctaacttc aatccgaagt atgctcaatt tgcgattaca attctaagaa
     3421 cttactacaa cttttgtcgc ccttttaaat cagcggataa aaaggttttg acacctgctc
     3481 aaagattagg gattacagat aaacaatttg attggaaaga tataatttat ttcaaatgac
     3541 aaaaagagct tggagtaatc ccaagctctt gtgctttatc tttactgttc ttcttcaatt
     3601 aacgcacccg ttaactcaat aagttttttc tttcatatac atgaaaatag tagttatacg
     3661 gatttttatc attctttatc cctttttggg caaatacctc attccattcc tcataattca
     3721 cttctggaaa aaaagtatct ccttcgaatt catgatgtat ttttgtgatg tacattttct
     3781 caacataagg gaaaaacaaa ttataaatct gttctcctcc gaaaataaaa atttcttctt
     3841 cgtttttaca taactcaaaa acatcttcta ttgaatgaac aatttcacaa ccattaaagg
     3901 taaacccctt atctctcgtc agaataatat ttcttctgtc aggtaaggct cttccgattg
     3961 attcaaggtt cttcctacct aatattatcg gatgtccctt tgtagtattt ttaacatatt
     4021 cccagtcctt gggaatcctc caaggaatgt cattctcttt gccaatcact ctattcttat
     4081 ccatcgcagc aatcaaagaa actttcattt ataacacagc ctttttaact aatttaccat
     4141 ctaatttctt atttctatca aaaaaccttt
//
LOCUS       DAFLWC010000148         4070 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.154, whole genome shotgun sequence.
ACCESSION   DAFLWC010000148 DAFLWC010000000
VERSION     DAFLWC010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4070
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.154"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            86..1435
                     /locus_tag="L1V17_002821"
     CDS             86..1435
                     /locus_tag="L1V17_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1237520.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(1563..2153)
                     /locus_tag="L1V17_002822"
     CDS             complement(1563..2153)
                     /locus_tag="L1V17_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBN1237521.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            2300..3652
                     /gene="brnQ"
                     /locus_tag="L1V17_002823"
     CDS             2300..3652
                     /gene="brnQ"
                     /locus_tag="L1V17_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBN1237522.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         1176 a          744 c          789 g         1361 t
ORIGIN      
        1 aaaattttgg aatcttagtt gtgtttttca gaaaactctc ttaatatgga agtaattaaa
       61 cttttttagt taggatgatt taaaaatgaa tgaagagcaa gaactgcagc gtggactgaa
      121 aaatagacat gtccaactga tttctattgg cggagcgatt ggaacggggt tgtttttagg
      181 ttccggaaag tctatccagc tagctggccc ttcgatattg ctcgcctatc ttattactgg
      241 atgcatctgt tttttcatta tgcgtgcgtt aggcgaactt ctgttatcaa acaccaataa
      301 ccattctttt ctggattttg ttgcagaata tcttggcaaa aaagcggctt tcatcactgg
      361 ctggacgtat tggttctgct gggtatcgat tgcaatggcc gatttaacag ccatcggaat
      421 gtatgtacgc tactgggcgc ctggtgttcc tcagtggctt cctgaactga ttgcattagg
      481 tcttcttctt tgcttgaata tggtggctgt ctcattgttt ggtgagttag agttttggtt
      541 tgcattgatc aaagttgtag cgatcattgc ctttatcctc gtaggagctt atatgatcct
      601 cacccactat acgacagata ttggcacagc cagtatcacg aatctatggt ctcatggcgg
      661 attctttcca actggtgcaa aaggatttat cttagctttc caaatggtaa cctttgcttt
      721 tgctgggata gaattagttg gattagtcgc tggagaaaca gaaaatcctg aaaaagtgtt
      781 gccggaagct atcaataata ttcctatcag gatcatctta ttttacttag gatctctttt
      841 tgtcattatg gcaatctatc catggaacag cttgaatcca gataacagtc catttgtaga
      901 agtattttcg gaaattggga tcacgattgc tgcttccttg atcaatttag tcgtattaag
      961 tgcagcagct tctgcctgca acagtgcaat atatagtaca ggacgtatgc ttcgttcttt
     1021 agcgcaagaa ggcagtgccc ctaaaaaatt caaaaagtta acaacacatc atgtgccagg
     1081 gaatgctttg acattttcta ctatcgtcat tttcatttct gttatcttga attacgtgat
     1141 gcctagtgaa gtattcacac tagtaagcag tattgccact acttgtttct tgtttatctg
     1201 gagtatgctt gtctacacgc acatgaaata tcgtaaaagt atcctcggca aaaaagctca
     1261 ttcatttaaa atgccgttgt acccatttag taattatctg gtatttcttt acatggcctt
     1321 tgtgtgtgtc gtcttgttcc taggaaaaga tacgagaatc gctttattac taacacctgt
     1381 gtggttcttg cttctattac taatctatca tatgaaatat gaacgtaaga agtaagaaag
     1441 tagttgtgac agaagtggtc agcttcgaga aataagaagg aatttacgaa aattgcttct
     1501 taaatttttg tgaaatttcg gcttatttct tggagataaa agcttctgtc ccagcctctt
     1561 ttctatttcc ccggaaacaa ccgctgataa taggcatctg cttttttata ggaaaaaatc
     1621 caaataccag atacaaaaaa acgtccgaat aacccgatca acggtacaaa aaagacaccg
     1681 gcaatcaagc ataagttaat catcatggag ataagacttc gacggtcctt tgacaaaact
     1741 ctcacgacat gggaatctgg tttatttgct ttcatgattt gcctcatcaa gataccaaaa
     1801 gaaaaactcc acatcgtgta tactaagaca taagccatct caggccaaaa agcttcaggg
     1861 ttacgcccga cccaactagt aacagaagga cataaagtca gccaaaagag caaaaagata
     1921 ttcgaccaga ccactcggta attaattcgt tctgccatct gaaatatacg atgatggttc
     1981 acccagatca ccgcaacaaa tataaagctg atggtataag ctaataatgt atttcggatg
     2041 acccataaag aatgaaagct agatgtatta gggatcttga tctctaatac aagaactctc
     2101 aaaacaatgg ctaccactcc atcagtaaat gcttctaatc tcgactttgt cacgatgatt
     2161 cctcctcaga tgattcagcg cttttatttt atcacttacg ttattaaata accatcgttt
     2221 tatataggga attttctgaa aattgttgca tatttttcga aattttgtta cttttaaaaa
     2281 aaccgtaaag gagttatgta tgacaaaaaa attatcattt aaagactatc tttttatagg
     2341 ctccatgctt ttcggtctat tttttggtgc tggaaatctt atctttcccg ttcatttggg
     2401 tcaagaagca ggcgctgcta ccttttgggc gaatctaggt ttcttggtta ccggtatcgg
     2461 tcttcccttc ttaggggtga ttgccattgg tgtatcgaaa agctcaggtg tatatgaatt
     2521 agcaaaacgg ataaatcaaa catatgcgat ggtttttacc atcttgcttt acttagttat
     2581 cggaccgttt tttgctttac ctcgccttgc aaccacatct ttcgagattg gtttagcacc
     2641 atttatcgat cctagcagac agacgctata tctagcaatt ttcagtattg tattttttgt
     2701 gctggcttgg tggttttcaa gaaaaccgac aaagatatta gattatgttg gaaagttcct
     2761 gaatcctgca tttttggttt tattaggtgc tttgcttctc cttgcttttt tgaatccact
     2821 aggttctgta aatcaagcgc ctattcagcc aaattatcaa gagcatgctt ttttcacagg
     2881 gtttactcaa ggatataaca cattagatgc gcttgctgct ttagcatttg ggatcatcat
     2941 tgtcacaaca atccaaaaca tgggtgtaac aaaacctgct gaaatcgcta aagacacgat
     3001 caaatctggt gcgatcagca ttatattgat gggaatcatt tatactttgc tcgcttattt
     3061 aggtgctatg agcttaggta gctttgctct aagtgaaaat ggcgggatca cgctggctca
     3121 gattgctgat cattatttag gtacttatgg cagtatctta ttagcattta tcgttatatt
     3181 agcttgcttg aagaccggta ttggtttgat tacagctttt gcagaaacat tcacagattt
     3241 gtttccgcaa agaaattacg cattctttgt tgcacttgct agtatccttc cttgtttagc
     3301 ggcaaacgta ggcttgacga atatcattca attttcgttg cctgttttga tgttcatcta
     3361 tccattagca atgacactga ttttactagt gttagttggt cctttgttta agcagcgtac
     3421 ggctgtttat cgaatgacta cttattttac attgattgct tcgatttttg atgggttgaa
     3481 cgcttgccca gaaactatca aacaaacacc tattgttcaa aatcttttat atgttgcgga
     3541 aagctacttg ccgtttttca aattggggat ggggtggatc gtaccagcag ttatcggttt
     3601 tgttatcgga ctgatttgga gtttcgctaa gaaagaagaa gtagcagatt gataaaagag
     3661 gttgtgaaag agacgttcag ccttgagcaa taaaaagtaa ttttgaaaaa tggcttctca
     3721 catttttgca taaatttgac ttaataccga gaaactgact tttgaacacc gtttattgag
     3781 aggtcgtgaa aaagccgctt agtttcaagt attaagaaat attttgtgaa aatggcttct
     3841 cacatttttg cataaatttg acttaatacc gagaaactgg cttttgaaca ccgtttattg
     3901 agcgtctata aactgacctg agtattagag aaacaaaacg gcaaagtagc tccatatact
     3961 ttgccgtttt gttttgaact aataccgaag agaagctgat caaacaacat ttcttttata
     4021 atatagattt tagacatata tatgatataa aaatagtttt cgcaaaaaaa
//
LOCUS       DAFLWC010000149         4059 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.155, whole genome shotgun sequence.
ACCESSION   DAFLWC010000149 DAFLWC010000000
VERSION     DAFLWC010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4059
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.155"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            30..1454
                     /locus_tag="L1V17_002824"
     CDS             30..1454
                     /locus_tag="L1V17_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1237523.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(1635..2408)
                     /locus_tag="L1V17_002825"
     CDS             complement(1635..2408)
                     /locus_tag="L1V17_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBN1237524.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(2405..3310)
                     /locus_tag="L1V17_002826"
     CDS             complement(2405..3310)
                     /locus_tag="L1V17_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1237525.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(3464..3784)
                     /locus_tag="L1V17_002827"
     CDS             complement(3464..3784)
                     /locus_tag="L1V17_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBN1237526.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
BASE COUNT         1220 a          751 c          815 g         1273 t
ORIGIN      
        1 aaagcggttt tattttggag gatgcttaca tggatacaga gcaacagaaa aaaggaattg
       61 gtttaattcc acttgctgcc ttagtaattg gttcagcgat tggaggtggc gtatttggta
      121 ttatgacgga catctccgga tcggctggcg gcccagctat tttcagttgg gtactcgtag
      181 gaacagcaat gttgatgctc tccttgtcga tcaataatat caataaaaaa cgtccagatt
      241 taaaaggcgg gatctttagt tacgcagaag aaggttttgg ccgtttcgct ggttttatca
      301 gcggttgggg ttactggctc acatgctggt taggcaacgt agcttttgca acattgttga
      361 tgagcgcatt aggatatttc ttcccagtat ttgaaggtgg gcaaaatctg gcatcgatcg
      421 tgatgagtac agtcttttta tggggatatg catggctagt gaatcgggga gtcgaaaatg
      481 ctagtttcgt caatgctatc gtcacattct gtaaattagt gccattattt ttatttattg
      541 tagtagctat cagcacgttt tcgatccaac aattcattga taacttttct agcgacatta
      601 tattgaatgc gaatggacag ccgatcccgt tttccagtca agtattgagt tgcatcatgg
      661 tgatgctttg ggtatttgtt ggtattgaag gagcctctgt cgtaggttca cgagcaaaaa
      721 aacaatcaga tgttgggaaa gcaacgattc tagggatatt cggcttgatt attatttacg
      781 tcttggtttc catgcttcca tatgggacaa tgacgatgaa tcagctgcaa acgatcaagg
      841 cgcagcctgc tatgggctat gtgtttgaaa tgatggttgg taaatgggga gcagtcgtga
      901 tcaacggcgg tttgatcatt tctttagttg gtgtttggct ctcatggacg atcttaccga
      961 ttgaaacaat gggaaacatg gctgaagacg gacttttgcc taaagcatgg ggaaaactca
     1021 acaaaaatgg ggcaccaact tatgctatcg tattgacgac gttatgtacg aatgtctttt
     1081 tactttcatt attattcact gacagtgctt ataactttgc ttacacactt ggtacagcag
     1141 ctattttctt cacgtggctt ttcttaggat tgtaccaaat gaaactttct tatcagcgga
     1201 aagaatgggt ccaattttta gtagggcttt tagcaagtgc ctttcaagta tgggctatgc
     1261 tagtcgtagc ctttaatgaa gtaatgcttg ttcttgttct tttcttgcca ggcatttatt
     1321 tttacctcaa agcacgtaag gagcaaaacg agcctgtaca acatatccac ttagataaga
     1381 ttttacttat aggtgtgacg atggtcggag tgattgcaat ggttttattt gccactggga
     1441 tgcttcacgt atagaagtat aaaagaagta taaagagagg ttgtgagcct gtcgtttatt
     1501 caaaaacata ctaggaaagg agctgtgaca caaatgttgt cacagctcct ttttcagaat
     1561 aaacggtgtt taagagacag ccaatcggca ataaggctga acgtctcttt cacagcctct
     1621 tttttgatga gtcatcatac attttttcgc ttaaatacga gatatcctaa tgctaagaac
     1681 aaaacgatgt aagctaaatt accgaatagc atttgattag tagaaagatg agtcaattgc
     1741 ttcatgatct cttcgtttcc aatttggttt tgcagattca acatactgat cggattccat
     1801 ttgatccact cccatttttg gatgagtgca ataaggatac cagatatgat tgacgaagca
     1861 aaataaaaga cgattcctgc tgagatggat gcgccggaac tattgataaa gcaagcaatc
     1921 atcaacacta aacttaaaat cagccataaa ccgatataac tacccaaagt ataagtgaac
     1981 aagctttgga tcagtgtttg accagtagaa accttctccg tgaaggaaat cgaagggaaa
     2041 agaatcagtt tcatcaacac agtgacaata atagctaaaa ggtataaata aacagaataa
     2101 ataactaatg tgatccattt gcttactaat atttctcctc gagaatactt tcgataaagg
     2161 agatttttca atgtaccata ttgtgcttcc atcgaaatga tcgtgcttgc agctgcaatc
     2221 atgataaaga caatccaaga tgtggcacta aaaagctgag cagtcatttc aactggatca
     2281 atgatcgtcg tgtatttttt ggctagaagt gctgttccta tgagcaaaac aactaataga
     2341 acagataaaa cagcagttga ctttttcttg atcaatttaa ataattcttg ttttacaagc
     2401 aatgtcattt ttcttcttcc ccctttactg aatccagaat ttccaataga gaagattcca
     2461 aatcattcgt cagatgctgg acgtctgtca catggatatt ttgtgcagac aatagctgga
     2521 tcacggttcc taataattct tcgttttctt ttaaaagctt gattttatca ggatcttcca
     2581 aagtatatcc agcttctgtc aagatcgttc gagcagctag atcatttgtt gtagagataa
     2641 cgatgaaatc ttgcgctgtt tggttcaatt cagccattgt acattgtttg atgatctttc
     2701 cttgattgat caggatcagc tcatcgacca ttttttcaag ctcgctgagt aagtgactgg
     2761 agatcaagaa agaggtgccc tgagtagcca agtcggtaat gatttttcgc acatctcttg
     2821 ttgcttgtgg atccaaaccg ttcatcggct catctaaaat aacgatagac ggatggttca
     2881 gtaaggcaag agcaattccc aatttttgtt tcattcccaa cgagtaggat ttcgcttttt
     2941 tgtgaatgta cttttccatc ttgagctgat tcacgatagt gtcgatagca gatacatcgt
     3001 tggtttcaga gaataacttc agatgatcat agcctgttaa gaatggatag atacccgggt
     3061 attcgatcaa tgctcctact tgttccaacc ctttatgact agagggagaa atctcatttt
     3121 caccaataca gattgttcca tctgagtaat ggatcagtcc taaaatagct ttcatgatcg
     3181 ttgtttttcc agcgccatta ggacctacta atccaacgat tttgccaggg gataagctaa
     3241 aactgacatc gctgagggct tgtttgtgac caaagttctt ggataattct tggaccgaaa
     3301 gacttttcaa aaatattcac tccttttcta tagatagtac aagcatacac ctgatgagtg
     3361 gagaagtcgc taggtcattg gacttatttc ttattttttc ataaaaaaat tgaatattaa
     3421 ataaaaaggc ttattttttc tgatcagtac ttattccaag tgtctagtgg ccgctagtaa
     3481 tcttgatgcc aatgatactg atgagtagca tccccacaaa gaaccaagtg gaaagattca
     3541 gcttatcatg aaacaagacc acaccaatta tgaccgaacc aactgcgcca atccctgtcc
     3601 agataggata agagagactc atcggcaaac ttttgattgc ctttgacaaa aagtaaaaac
     3661 tagcaatcat gccaatcact gtgtaaaaag aataattgat tttagaaaaa ccatcactcc
     3721 atttcatcat cgttgaccag aatacttcca aaattcctgc tatgattaat tccatccatg
     3781 ccatacttac attcctcctt aactataaaa aaatacacaa aaagaggaaa atcatccctt
     3841 caaagaccta atggaatgat catcctcttt atcctacccg gtggcagatt gtatatcttt
     3901 ttctgtagta tagcacacct atccagatat cggcaatctc atacttttta gtaaagtgta
     3961 ccaagcactg acggatatat cgttagcgga aaagaagatg aatgctttgc aatttcatag
     4021 aaagaagttg ttatttatta atcatttaaa aaaaacagt
//
LOCUS       DAFLWC010000150         4033 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.156, whole genome shotgun sequence.
ACCESSION   DAFLWC010000150 DAFLWC010000000
VERSION     DAFLWC010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4033
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.156"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(143..1648)
                     /locus_tag="L1V17_002828"
     CDS             complement(143..1648)
                     /locus_tag="L1V17_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBN1237527.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDPFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(1645..2331)
                     /locus_tag="L1V17_002829"
     CDS             complement(1645..2331)
                     /locus_tag="L1V17_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1237528.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2524..3945)
                     /gene="gndA"
                     /locus_tag="L1V17_002830"
     CDS             complement(2524..3945)
                     /gene="gndA"
                     /locus_tag="L1V17_002830"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HBN1237529.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1109 a          854 c          691 g         1379 t
ORIGIN      
        1 atacttacat ttaattaacg gatgttattc tatttaattg ttcgctagtt tttttataat
       61 gacatccctg aatttctcac ttgcttgtat tttgtacctt attctttgtt ggatatataa
      121 aaaaacaagt aaagcacatg ctttacttgt cttctgcctt tgcgatagga ataaagattc
      181 taaaaattgt cccttgccct actacacttt ctgctaagat acgtccttta tagttttcaa
      241 ccagttgttt agcgatagac aaccccagac catttccacc cttcgttcta gctcttgctt
      301 tatccactcg ataaaaacga ttgaagatct tattaaggtc ttctttgggt attccttcgc
      361 caaagtcctg aatcgcgatc tcaaattcat tcagagtgga agaaatagag atatggactt
      421 cttttcgtgt agttgaatac tttactgcgt tatccaatat gataatgatt aattgttcaa
      481 agtgattacg ataaatttgc agggtcactt cttttgtcaa atcatcatct aaagtgatca
      541 catagtctgg atataatatc ttgaaattat tataaacttg ataggtgact tcttttcctt
      601 tagttgtttc attcgcataa tgaacatcta cttgttctgc tcttgataag tctagcatct
      661 cttgaactaa gcttttcata cggctgattt cttgcatgct ggcgcttaat gattcttcta
      721 atatctcagg atcatctttc ccccaacgat ttagcagact aagatgccct tcaataattg
      781 caacaggtgt ccttaactca tgagatacgt cttccacgaa ttgctcttgt tgttcaatat
      841 acaaacgcat acggtcaagc atctcattga atatttcagc taaatctgcc aattcatcat
      901 ttgtgtcgat ttcaggcatg tggatatctg attgcggatc tttacgtata gtatccattg
      961 tatctctgag taccttgagt ggttttaaga aataagaaga taaaaagaaa cctaaaatac
     1021 tacttaagat caaagaaaca acttctaaaa caataagagt caataatagc ttatttcgaa
     1081 tatcatagaa agaagataat tcatagaagc tttgcgcata gccgatcttt tctcttgtac
     1141 ctttagaata tataggctgg atagataaaa agccagtttt tccttctagt gtaacgatcg
     1201 ttggaacttt acgtgtagtc tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca
     1261 agttctcgtc caaatcataa acataaagat ccattgatgg ctgccctagc tcagctataa
     1321 agggatcgat cttcattaag tttccttcga ccagtgaagt atgatctacg acctcatctc
     1381 cgtcatttgt cgctttcgtc agattacgat acgtatttac taatgtcagt tcttcatccg
     1441 agttagccaa acgagaagct acttctgaaa tcgtacgctc tacattgttt ctttcttttg
     1501 ccacaatcag attgatagat gatttatagg taatgacagc gaaaattgta aacacaacga
     1561 atatgaagaa agaactcgca aaggcccact tgattgtcaa ggagggccct ttcagttctc
     1621 ttttttccga ttttttcggc tttatcacga gcgcatcaca taacctgttc cgcgtacagt
     1681 ttggatatag ctttcctccc cgggaacgtc aattttgttg cgaagataac gaatatatac
     1741 gtccactacg tttgtttcaa cttctgtttc gtatccccac actttattta gtaaaacgtc
     1801 acgtgctaat accacgttca cgttttccat taaagtaagc agcaactcgt attctctttt
     1861 tgttagttca attacttcat ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa
     1921 atcgcgataa gtaatagtag tttgtttagc cacattttta tcgccttcaa tatcgattcg
     1981 acgcaacaat gcacgaagac gtgctaataa ttcttcgata gcaaatggtt tgacgatgta
     2041 gtcatctgct ccgtggtcaa gtccagatac acgatcgatc acagaatctc ttgcagtcat
     2101 cataatgatt ggtgtatttt tgacttggcg tacacgtctg cagacttcta aaccgttcaa
     2161 ttctgggagc atcagatcca acaatatggc atcccactca ttatttaatg ccgcatctaa
     2221 accagttcgg ccgttgtagt ggacttctgc gttataccct tcatgcttca actctagctc
     2281 gacaaatcgt gccaagttct tttcatcttc aatgattaga atattgctca tttattattt
     2341 tatcctttct attctactgg ctttttaaaa actctatcat tataccgata atatgcttaa
     2401 aaatctatag tcattttatc atggatagca attttaaaaa agagctgaag tctactcata
     2461 acaatcgact tcagctcttt cgtcctcttt ttattttctc atttcctaac agccgaaaga
     2521 ctattattct tcatggtacc atgagtaatg gaagattcct tctttgtcga cacgctcata
     2581 ggtatgtgcg ccaaagtaat cgcgttgggc ttggattata tttgcaggca gacgttctgc
     2641 tctgtatgaa tcgaagtaag cgatggctga tgagaaagtc ggtacaggta cgccagcttg
     2701 gacagccaag gcaacgacgt ctctgactga ttgctgatat tttttcgtga tttcaacgaa
     2761 gtaatcatct agcaataaat tttcgatctc aggatttttg tcataggcat ccgtaatttt
     2821 ttgcaagaat cgagctcgga tgatacatcc agcgcgccag atttttgcga tttcaccaaa
     2881 tggcaagtcc caatcaaatt cttttgaagc gacacgtaat tgagcaaatc cttgggcata
     2941 actcatgatt ttactgaaat acaacgcttc tcggattttt tcgaccaatt cttttttgtc
     3001 tcccgtgaac tcaaaatcgt tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc
     3061 tttataagca gaaatatagc gggcaaatac agattcagtg atcaatggaa gtggcacacc
     3121 taagtcaagc gcgctttggc ttgtccattt acctgttcct ttattcccag ctgcatcaag
     3181 gatcacatct actactggtt tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc
     3241 agtgatttct atcaaatagc tgtctaattc gccttgattc cattctttaa agatatcagc
     3301 catttcttct actgaaaggt ttaaaatatt cttcattaag tcataagatt cagcaatcag
     3361 ttgcatatct ccatactcaa taccgttgtg taccattttc acataatgtc cggctccatt
     3421 tgggccaata tatgtgacac atggtgctcc gtcttctgct tttgcagaaa tttgctctaa
     3481 gattggtgca actagcgcat aggcttcttt ttgtccacca ggcatgattg aaggtccttt
     3541 taaagctcct tcttcaccac cggaaacgcc tgtaccgata aagttgatgc cagagttggc
     3601 taactcttca ttacgacgca tcgtatcttt aaagaatgta tttcctccgt caatcaaaat
     3661 atcgccttta tcaaggtgag gaagtaactc ttggattgtt gcatctgttg ccggtcctgc
     3721 tttgaccatt agcaagatcc gacgtggttt ctcgatagat tctacaaatt cttcgattgt
     3781 atatgttgct ttgaaatttt tatctgggtg ttcttctact acagcggttg ttttagcccc
     3841 tgtacgattg aataaagcca ctgaatagcc gcggctttct atgttcaagg ctagattttt
     3901 acccataacg gccataccga caacgccgat ttgttgtttt gacatatgaa ctcctcctac
     3961 atacgggatt tctccctaat ctcttacatt atagcttaac acggctacat tgcaaactaa
     4021 agaacaacat att
//
LOCUS       DAFLWC010000151         3923 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.157, whole genome shotgun sequence.
ACCESSION   DAFLWC010000151 DAFLWC010000000
VERSION     DAFLWC010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3923
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.157"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(573..1130)
                     /locus_tag="L1V17_002831"
     CDS             complement(573..1130)
                     /locus_tag="L1V17_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237530.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(1309..1920)
                     /locus_tag="L1V17_002832"
     CDS             complement(1309..1920)
                     /locus_tag="L1V17_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237531.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(2033..2290)
                     /locus_tag="L1V17_002833"
     CDS             complement(2033..2290)
                     /locus_tag="L1V17_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237532.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(2887..3165)
                     /locus_tag="L1V17_002834"
     CDS             complement(2887..3165)
                     /locus_tag="L1V17_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237533.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(3199..3450)
                     /locus_tag="L1V17_002835"
     CDS             complement(3199..3450)
                     /locus_tag="L1V17_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237534.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT         1194 a          799 c          520 g         1410 t
ORIGIN      
        1 ttattccgaa taaatggtgt ccaaaagctt gcatctgcca gattatctca tttcttatga
       61 caagctaagc aaattatctc caccaaataa tttattcata tttttgactt gcgcatacta
      121 actaattctt aaattttcat acaaaatttc tcaatttccc ttaacgagta atatttatgt
      181 acggtgattc tcactagtat cccaatcact ttttaagtta tcccgatttc aattctactt
      241 caaaaatagt tgcttttatg tatgctgtta gttgattaga tggtcatttg ttgagctagg
      301 tcgtttattt taaacaagtt gtttctttag cttataccta tctcgtctac caaacgcaag
      361 atggcaaaca caaatgcata cgcatctgta tttgccactt tgattcgtat aaagctaaca
      421 actattaact cctctcagct aatagttgct ctctttttta ttcagattca tttttgctga
      481 tcacagccta gtatttcaat ggttttgaac actaaaccaa attgttccat tacaacattc
      541 actggctgat gaaatggatt agtagatttc gattattcaa agcgattttc tattggtgga
      601 tcgtgttccc aactaataag acggattcca aacctatcgt acagatcttc taaaccactt
      661 ataaattttg cacctatttc aggtgtttta ttgcgtggat attctattgt tacgccatta
      721 aatggatacc aattaggatt aggctctctt tttttctgta catctcccat agaatagtta
      781 gcactttctg ggacataata tattcttcga ccatcctcta attcatctaa taagatattt
      841 cgtgatcgtc tatcacttgc taaatgtaga cgccacgtgc gataccatgc catgctacct
      901 gcatctgcag aaaatccatc aaataatgca acaattgtat cttctatcac aatcctttcc
      961 ccatctactt catattctaa tctaaaatca aactcccctc gggtaatttc tggtcttggt
     1021 ggcttaggac ccaatattat tctacttaaa accgcattcg ttcccagatg aaacacagct
     1081 ataacaacaa taatgattaa tattttgttt ctatttgata aatttctcat tattcgcaca
     1141 tcacctctac attctcacat attagttcgt aatactcctt taatatcaaa atatctactg
     1201 gtcgtaataa tattcgctat gaattcctac tactcgtata agaaaggcca aatcatcagc
     1261 ttttacttgc tgatgatttg gcttgtttct atttatcgta attgttttct aatcaccaaa
     1321 attgttaaca atcggttcag atatttccca gttgattaag gtaattccgt attgtgtcaa
     1381 aacttcttgc gcttctccga aattaagtac agttcttatg tatccacttt ctcctaatat
     1441 aaagtctacc tctcttttaa aaccttcctc gagatttcta agggctatat gtggttttaa
     1501 tgacattgat tgtacatttt cccccatata atattgcgca cttcctcgac taaaatagat
     1561 tcctagatcg tccccaaaag gtagatcttc tctaccacta gctaatctac ttctccatct
     1621 tcgttctctt ttcatagaac ctgcgctgaa ctcacacccg ttaaactcag ctatgacagt
     1681 atcttcaatt atgttaatct gtccatctag ttcgtattca atcctaaatg gaaattctcc
     1741 ataggtgatt tccggttcgg gtattttagg tgagattaat gcaaagaaag gaaatattaa
     1801 gcttggcaac atcaaaaaaa ctcctcctat gatcacaatt cccgatgtaa tccaaaatat
     1861 aatttgtaca attctcattg atccattgta ttccatttta ttccccctat tactattcat
     1921 atccgcctat ctatatcgat cttccaatgc agagataatt gcttccatac cttgattttt
     1981 tactgagtta cctatgcgag atatcattct ccactaaggt gcatcatatt gtctatctaa
     2041 catgattaat tctccaatag gtgtatactc ctccaaaaac aacatttaat gcatctccct
     2101 cgacaacata agctaccatg tttgctgtat atgtgtttga gtctaattca taagcagata
     2161 aatttactgt cgctggatta aatataatcg cattcgtatt tatagctact gaatttgctg
     2221 cttcagcacc accttttgaa tgtccgatca ttgtgatttc aatagtagga tttacgtgga
     2281 cagccctcac cgtttaccct gaccattata gaaatcgctt acttttttga actacgcaac
     2341 aaaggataca atgctcctaa cttcactgtc tccatttttg tccactaagg aatataaaaa
     2401 ataggcatta attcatttaa ttcggtcaca acacgttacc ttttaaatca ttatactgta
     2461 tctcatacat tattatcaat aaactattat aaaaatgcaa aaaatgcttt atcaatctat
     2521 tttgtaattg gtcataatat cattgaaatc ataccctgta tcgatttttc ctatgaatct
     2581 cgtctatttg tgattgacga aaaagaggca agacagacac tggaatggta attttaccca
     2641 ctattttgct ccaactattt gtaatcgtac ccacttttga aataccgaga tgatcatttt
     2701 aattgatatg ctgattccca agcaaaaccc caagaaatta aatgctctat cgcatctagc
     2761 ttcttgggtt ttgcttatat aaattccaac atttaaattt tttatgctgt tcggtctcag
     2821 aaatgccgtt tttgcttata tcacaatatc aagatgtcaa attattcgtg ttgccgatga
     2881 ctttgattaa tttttttcaa attgtttatt aagactaatg ctgtcttttt gcagatacca
     2941 atgttcgaac tttttaacat tatcatatga tcctgcaagt tttaacttct taccattaga
     3001 tgttatcaaa gttataatta accttgcctt tttcccatta ggatctttta ttttatgaat
     3061 tttctgcagg taatctctcc taatggcagc tatttttacc tcatcagtgc tgataaacca
     3121 ttgatcatcc acatacatac tgcctgttat gttgtgtttt tccatttctt ccgagaacga
     3181 aaagtttaag gctcgttctt acttccaaag ttgaatgagt ccatggattg gacttagtgt
     3241 gagaattgag aacaacaata agaatccata tcctcccgca aacatcccta aggctatact
     3301 gtctctccat ccataagtag gattagaaga gaaaagagtc accgtttgta ataatatgaa
     3361 aaggaataat ccagcacaaa caccaaagat aacaactcca aacattgaat ttttatacaa
     3421 tgaccattta tttataggct tttctttcat tttacttccc cctactgttc tgttcacacg
     3481 gaatgaattc aaagttcata agccctcctc tttgaacata tgaatacgac ttgctaacta
     3541 tactttaaaa aagcttgttt taagcggtta taggcgagtt gtaatctcta ttcatctcat
     3601 tagcaaataa cttgccgaaa agtctactga aattaaagca gatagtggaa gaattattta
     3661 gccaggatag acactatttg tgaaacacat gtctttactt ttgaaattct atgatgaaaa
     3721 gccttggaat acagtagctc ttaattggta atactttttc cattataaat aacctctttt
     3781 cattttatat ttatcccctc taaaaataat atctaatcta atattttaaa cttatatttc
     3841 cctcgctgtg ctaatagagc attactaaat aaatagaaac tagaaaaaag cattacgcct
     3901 gccagaataa accaattatt tgt
//
LOCUS       DAFLWC010000152         3876 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.158, whole genome shotgun sequence.
ACCESSION   DAFLWC010000152 DAFLWC010000000
VERSION     DAFLWC010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3876
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.158"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(716..3865)
                     /locus_tag="L1V17_002836"
     CDS             complement(716..3865)
                     /locus_tag="L1V17_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HBN1237535.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMEPVKKESYLDPTVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
BASE COUNT         1076 a          803 c          635 g         1362 t
ORIGIN      
        1 actaatacag gtagtcctct tttttgttat tttgatattc taaatcattt tttattggat
       61 tattcccttg ttcgatatag acccaaattg atctatcaat aattatcaaa ctgagtcata
      121 tagagacaaa aatttcaaaa atgacctgtt aaatggtcat cgaatatcat ttaaaatcaa
      181 tacgacggag tcagacacgg agtcaaaaca agcccgctga gagtaaaaaa tatatacagt
      241 cccataggta aagtgccaca ggactgtata tttttttatt tgagattacc tgaaatgatt
      301 ccatttactt tttatctcat tttttcctac tagttagtat caaatactct cctattttct
      361 caataaacta ttttgggtta catggtatct gaaacagcta aaaccttgtc attacagcaa
      421 aaaatcactt tatctccgtt tcatttcaga tacatttcac ttaagcggat tccaaaaaaa
      481 caaaagaaaa aggaacccct agttagccta tgctttttat tggttcctct caaaacacgg
      541 tcatataaca acggggtggg gtaaatgaat gaaaaaggtg gaggaaacat tattcaatag
      601 ctgtcttaaa tacttcgtta taaaatgtga acaaataaaa gacatctatc cctattttct
      661 acacttccac tttactacca tctttgaatc gtacaatttt cttaactctt ctcgtttacc
      721 tcaattcatt ttcaagtgga atcagctcat catctaacat tttacgccat gctcgcttca
      781 tttcttgtgg gtatttaaat ggcttcgctt ctggatggtt ggctttatat ccttcgtaat
      841 ccttactgtt gataattgct ttcatattag gaattggatc ttcacctggc atatattgca
      901 gattagaagc atgtaattct ttctcagaaa caaaccactc attggaaaag acatgaatca
      961 aatcatcact cgcttgtgta aaatagcgac gtttaatgac aaagatatct tcattactat
     1021 ctaaagtccc cacatcaaac gcatttaaaa tttgtcggta aacttctttg actccttctg
     1081 ttttattcaa tttagccaaa gctttttcaa tttcttctcg tgcatctgaa ctattcgccg
     1141 cataagttcc tagtaattga tcaatataag tagaatcaat atcatacaac ttcgtggtat
     1201 tttcactata aaattcgatc gtggaaaaat cttctccctc tttttctggt tcttcctcta
     1261 ttaatgaacc cttcacggtc tcgtacacgc caatttgttc ttccaaaagt tgaatttgat
     1321 tgttcaaggt tgaagatttc accatgtcat cattgtaatc gtcataagtc actaacgatt
     1381 cataagcacg attcaattct tggaatgctt tgacgtactc gatacggatt tcaagtggcg
     1441 tatgttcatc aatggattcc atggatgaaa cctcttttaa cttaccatat gcttgcttga
     1501 atcttttttt ggattcctga taacttggat aaatcaaacc cgattcttct tttgcttctg
     1561 aatacagttt tgtcgcatcc tcgacattct tctccattgt ggctggcttt cggaaagtaa
     1621 caattagtcc ttttgttttt tctggatacg tacggttcgt acgtgaaaaa gcttggatca
     1681 atcctgcata ctctagatta cgatccacaa atagggtttg aatcgtaggt gcgtcaaaac
     1741 ctgtcaatag acgatccact acgatcacta aatcaatttg tttcccaaat tgtttgaatt
     1801 ccgctctttt tcgtgccaaa cgattattga tgtctccgtt ataacgctca atgtctgcta
     1861 atgaccagga agtatcataa tactgattat attcctcaat aattttttgc atttcttctt
     1921 gttggacact tgaatctcgg ctgttttctt ctaatgaata ggtaatagcg attcgtggaa
     1981 aatcaggatc ctccatcgtt cttccttcac gaatgggctg attaggaaac tcttttgtta
     2041 accagtcagg ttctttcgtc atttctttga tcgctcgata atactttttg gccatgtcaa
     2101 tggaactcgt ggttaagatc gcagacttcg ttggacggcc atttcgaaaa tcaaattttg
     2161 tataggcatt gtctggacgg aacattttat gaatgacttt ttggatatgt tcatctgctt
     2221 caaaaacagt agggtccaaa taactttctt ttttgacagg ctccatttga tcaatcatac
     2281 gattgatctg ttccggtgaa tactctgcat atgtttctac ttcttttaat ttccgataga
     2341 ttttattctc taatgaagtc ggctccacgg tgttttcatg ctctacttga aatcctaaaa
     2401 ccgagccatc ttctaatgca ttcttgatgg tataggtatg caagacctct ccatactgat
     2461 catgggtcgt acgtgccaat tgccctttgg cttgtttccg attctcaggg aaaatcggtg
     2521 tacctgtaaa gccaaaccaa gtggatttcg gaaacatttt tttgatttct tccatatttt
     2581 cagcacttaa cgctcgatga cactcatcta ctacaaacac gatatgttgc cccattaatt
     2641 tttggaagcg attggttcct tttttctctt cttgtttttt tgcatatttc aacgccgcat
     2701 ctagcttttg acgggttgta ataatcacaa catttgcatt ggcatctgcc aacagagttt
     2761 cacttaactc tttggcactt cctgttccca cgatcaagct attcgctttg gcgttcccgg
     2821 aagaaatccc agtattaaat tccgaagcaa atttcgtaaa ctctgtggtg gtttgattat
     2881 ctaaatcttt gcggtccact aacatgatcg tccgatcgat ccccgatttt cgtgctaaaa
     2941 gcttagtaga tacaaaacta gtcaacgttt ttcctgaacc agtcgcatgc cacacatatc
     3001 ctgattgatg tttatttgca gcaataaaca aggcttgaat cgcatgtact tgataaggat
     3061 gtaacaccat gaggatttta ttgtcttgat cttcactgac aatcgtataa tccgcaatca
     3121 agcgatgagc atccgggata tttagcactt gtttgcaaaa ctcatataag ttttctacct
     3181 ttttattatc tttcgttcgc caactaaata aaaacttagg atgcaaatcc tttggtaagg
     3241 catttgcaaa ataccgagtg gtttgttcat tggaaaccac aaacaactgt aaggtcgaaa
     3301 agatattgtt ccgaaacata ccttcttctg catatttttt gatttggtta aacgcctgat
     3361 aaaaactatc ttttgcggtt acttgtttca gctcgatttg gacaatcggt aatccattga
     3421 tcagtaaggt gacgtcaaaa cgtcgatccc gtgcttctat gttacttcca cgttttgcaa
     3481 tttgatggac cacttcatag gtagagattc ctccaccaat gtcttgatta gaataaagaa
     3541 tgagcgagac agaacccagt tgcggatctt cccgttcaat cgtgatccga gccattccat
     3601 tttcaccttt taaccatttc gcagcatcaa agggggtttt cgttcgtagt aacaattctg
     3661 ttttgatcgt ttcaaattct ttatcggtca aaggaaaatc attcagttct gcttgattat
     3721 ttgagatgat tttttggcgt aaattgaccc aaagatcttc ttctgatttt agatcgggac
     3781 gatacgtcca ctgattatgc ccttccccca atacacggat caactgttct tcgacttccg
     3841 cttcctcacg gtgactaatt ttcatttatc ttccct
//
LOCUS       DAFLWC010000153         3738 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.159, whole genome shotgun sequence.
ACCESSION   DAFLWC010000153 DAFLWC010000000
VERSION     DAFLWC010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.159"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            72..155
                     /locus_tag="L1V17_002837"
     CDS             72..155
                     /locus_tag="L1V17_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBN1237536.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            280..1017
                     /gene="erm(B)"
                     /locus_tag="L1V17_002838"
     CDS             280..1017
                     /gene="erm(B)"
                     /locus_tag="L1V17_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBN1237537.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1280..2143)
                     /locus_tag="L1V17_002839"
     CDS             complement(1280..2143)
                     /locus_tag="L1V17_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBN1237538.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(2145..2417)
                     /locus_tag="L1V17_002840"
     CDS             complement(2145..2417)
                     /locus_tag="L1V17_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBN1237539.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            complement(2434..2643)
                     /locus_tag="L1V17_002841"
     CDS             complement(2434..2643)
                     /locus_tag="L1V17_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HBN1237540.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
     gene            complement(2742..3638)
                     /locus_tag="L1V17_002842"
     CDS             complement(2742..3638)
                     /locus_tag="L1V17_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBN1237541.1"
                     /translation="MIQYYYTKKEWGVVMEKEKLKILEELRRILNNKNEAIIILNNYF
                     KGGVGKSKLSTMFAYLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKN
                     GNLASSIIHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIII
                     DTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFV
                     PYLVDTDSATIKSNLEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVL
                     SMYENVFFEMIERIIQLENEKE"
BASE COUNT         1148 a          654 c          579 g         1357 t
ORIGIN      
        1 aaattttgta taataggaat tgaagttaaa ttagatgcta aaaatttgta attaagaagg
       61 agggattcgt catgttggta ttccaaatgc gtaatgtaga taaaacatct accgttttga
      121 aacagactaa aaacagtgat tacgcagata aataaatacg ttagattaat tcctaccagt
      181 gactaatctt atgacttttt aaacagataa ctaaaattac aaacaaatcg tttaacttct
      241 gtatttattt atagatgtaa tcacttcagg agtgattaca tgaacaaaaa tataaaatat
      301 tctcaaaact ttttaacgag tgaaaaagta ctcaaccaaa taataaaaca attgaattta
      361 aaagaaaccg ataccgttta cgaaattgga acaggtaaag ggcatttaac gacgaaactg
      421 gctaaaataa gtaaacaggt aacgtctatt gaattagaca gtcatctatt caacttatcg
      481 tcagaaaaat taaaactgaa cactcgtgtc actttaattc accaagatat tctacagttt
      541 caattcccta acaaacagag gtataaaatt gttgggaata ttccttacca tttaagcaca
      601 caaattatta aaaaagtggt ttttgaaagc catgcgtctg acatctatct gattgttgaa
      661 gaaggattct acaagcgtac cttggatatt caccgaacac tagggttgct cttgcacact
      721 caagtctcga ttcagcaatt gcttaagctg ccagcggaat gctttcatcc taaaccaaaa
      781 gtaaacagtg tcttaataaa acttacccgc cataccacag atgttccaga taaatattgg
      841 aagctatata cgtactttgt ttcaaaatgg gtcaatcgag aatatcgtca actgtttact
      901 aaaaatcagt ttcatcaagc aatgaaacac gccaaagtaa acaatttaag taccgttact
      961 tatgagcaag tattgtctat ttttaatagt tatctattat ttaacgggag gaaataattc
     1021 tatgagtcgc ttttgtaaat ttggaaagtt acacgttact aaagggaatg tagataaatt
     1081 attaggtata gggcacctct aataactacc aattaattca cctcaaaatg aaattagaaa
     1141 aaaacagcga aatttttaaa tctatttctt atcgatacaa attcctcgta ggcgctcggg
     1201 accccaacat gaggaaatgt ttttataaaa aaagagtagt taccgttttt tggtaactac
     1261 tcttttcctt ttttaaggtt taaatacctg gaagtttagg tgttttgggt attggtggtg
     1321 taggtagctg caagctttcc attttttgtt gaattgcttt aaattcaggg gtttcttggt
     1381 gttgattttg aaccattttt tgctctattc tctccaaagt cggttgaatt tctttccctg
     1441 atactttacg atttaattct ctttctaagg tctctttcgg actaatggaa ggcgtttcta
     1501 agcttgaata gagtttcact ccttctctat tgtaaagcct tatatcgcta aataagcccg
     1561 ttttatgaag ggtttctaaa ttggtcggta agtttttgac aacaatatca tgcgcttgtt
     1621 ttggtgttgc cctagctgtc attggatcat ctgcatacat ggtttcatat cgttcaatcg
     1681 ttcctaagta tgattcaatt ttcggtactg ccatgacgta tatttttgtt tcataacctt
     1741 tagattgaag cattgtggct gtttgaatgg gaacgtctgt tgttcgtcct gttccttcaa
     1801 tcactaaatt atagccttga tcgcttaaac ggctaataag tgcttctgtc atgcgattcg
     1861 aataaggggt aacgtgtttt actacgtctt tttcatagag tttcactaat tcgtcaaaat
     1921 ttgggtgctg ttgtttaaag gtatcattat caatgacaat aacattccct tgtgtttctt
     1981 caaaaattgc tgatcgcaaa ctggttttcc ctgaccctgg ttgcccacca agtaaaaaag
     2041 cggttggcga ttcaaccgct agtctatttt tagttagtcg ttcaacattc ttttctaaac
     2101 gatcttcaaa ttgcttttcg gtgaagtcag taatattcgc catgttaagc cactttctct
     2161 ttattcaaaa tttgttttga atattgattc attgaccgcc aatactcatg aatagcttgt
     2221 aattcttcaa atggttgttg aaataaatca acttcttgtg ccacttctaa ttgatttaaa
     2281 agattcactt ctagtaaacg agtattttta gtatctagtt catgattcaa aacataattt
     2341 aatacccgat tataaacact tgccgataac tcattaatga tttcaatttc aaatgttttt
     2401 tcatacgtaa ctgccatttc attttcactc cttttaaagt ttgtcaggta aatatttccg
     2461 tatatattct tctaaggctt gatccataac ttcttttacg tttccgccat tctttgctgt
     2521 ttcgattttt atgatatggt gcaagtcggc acgaacacga accgtcttat cccccattat
     2581 atcttttttt gcgctgattg gcgtatcatt tcgttttgct ttctgtgcgc ctaaatttcc
     2641 cacgatcgct cacttctttc tatttcttct tactatttat tttatcatca cctatcacaa
     2701 atcacaagtg atttgtgatt aatcacttgt gatttgtgat tctattcttt ttcattttct
     2761 aattgaatga ttcgctcaat catttcaaaa aatacgttct catacataga caaaactttt
     2821 ttgtcatagc ctttgtgttc tgtaatgcca tttttagacc aagtacttac tttattactt
     2881 cgcttgataa tatttcggaa aaccaaatta tcctctttat gttctttgta cagttcttcc
     2941 aggtttgatt ttatcgttgc gctgtccgta tcaactaaat aaggaacaaa accaatcata
     3001 tctagtccag ggttaaactg ttcttgcaaa tcaatcaaat aggaaatata gttttgaatg
     3061 ttgtttgtac tttcttcttc tgcttgtaaa gggatcataa cgtaatcact cgccacgatt
     3121 gcattatttg tataaacgct tggcgttggt acagtatcaa taataataag atcatagtca
     3181 ctttttaaag gtgctaaaag agtagcaagc aatctacttt cattttcaaa cgtccatgag
     3241 cgagttaatt ttggcagtaa catcaaatca aacgtgccag ggatcaagtc taaattatca
     3301 gtcaaatgaa taatagaaga agccaagttt ccatttttca agccttcata aaaattgaca
     3361 cgtggcaatt ctacctcaaa agtttttgct aagtcttttg tcaatgttgc ctgtaagtcc
     3421 ttatcgatca ttaaaacttt taaattcaat ttgtctgtca agtaagcaaa catagtcgat
     3481 aatttggact ttccaacacc acctttaaag taattattca agataataat tgcttcattt
     3541 ttattgttta aaatacgtct taattcttca agtattttta gtttttcctt ctccataact
     3601 acgccccatt ctttttttgt atagtaatat tgtatcatta agaatcacaa atcacaagtg
     3661 atttgtgatt aatcacttgt gatttgtgat aagtgatttg tgattaatat ataaaagccc
     3721 tctttaaagg gcttttat
//
LOCUS       DAFLWC010000154         3735 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.160, whole genome shotgun sequence.
ACCESSION   DAFLWC010000154 DAFLWC010000000
VERSION     DAFLWC010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.160"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..1087
                     /locus_tag="L1V17_002843"
     CDS             <1..1087
                     /locus_tag="L1V17_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1237542.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1305..2447)
                     /locus_tag="L1V17_002844"
     CDS             complement(1305..2447)
                     /locus_tag="L1V17_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1237543.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2452..2637)
                     /locus_tag="L1V17_002845"
     CDS             complement(2452..2637)
                     /locus_tag="L1V17_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBN1237544.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(2991..3236)
                     /locus_tag="L1V17_002846"
     CDS             complement(2991..3236)
                     /locus_tag="L1V17_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1237545.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3230..3631)
                     /locus_tag="L1V17_002847"
     CDS             complement(3230..3631)
                     /locus_tag="L1V17_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBN1237546.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
BASE COUNT         1230 a          676 c          566 g         1263 t
ORIGIN      
        1 agatatcaat gatgatggct caagaaaaaa agtggagaaa gttggcggag acacccgacc
       61 agaggccgaa gctgctttac gaaaagtttt atcagatatt gacgaaacag gacaatactt
      121 tttaggtacg gatactcgag taaaacaata ccttgatttt tggatggagg aatacgttaa
      181 actaaatcta aaatacaata cctatgaaaa ctaccgattt accatcaaaa atcatataaa
      241 cggttattta ggaaagaaaa aacttacgga tctctcccct gctcttttac aaaatttcat
      301 caatgctgaa tttaaaaagg gttactcgaa gaaaacaatg actattactc actctgtcct
      361 taagaatgcg ctgaatatgg cggtttatcc ttggggatta atcaagcaaa atcctatgct
      421 gtatgtaaaa ataccaaaat atgaagcacg accaacgact aaaaaagatc taaaaatcat
      481 ttctcttgag gactttgatc atatgctaga aattactcct gaaggacatc ctttctatat
      541 tcctttgaat attggatttt atacgggaat gcgcgttggc gaagtttgtg gtctgacgtg
      601 ggatgatgtc gatttttcaa atggaacaat tactgtagag aaacaaatgg taaagaatga
      661 cggcgcatgg gtatatggta cgccaaagac aagcagttcc aatcgaacga tttttattgg
      721 acaaaccttg ctagcaattc tgaaaaaaca taagaaacaa caattagaaa atcgaatgaa
      781 gtatggaaag ctctacattg attcaaatgc agtatgtacg aaggaagacg gtgagctagt
      841 tacgccaagt gtagtgaaat ggaatactag gaggatatcg aatgcactct ccctctcttt
      901 taacttccat tctctcagac atactcatgc tacacttctt ctcgaaaatg gcgcaaaaat
      961 gaaagaaatc tctgaacgat tgggccacag cagaatttca attacgatgg atacttactc
     1021 gcatgtaaca gataagatga gaaatgaaac ggtcgatatc atggaaaatc ttagaaagaa
     1081 ttcttgattt ttgccaccga aaaaaaccac cggtggcaaa ccggtggcaa atccatgtaa
     1141 acatggttta ttttttacac tgttttcaaa caaacccttg ctatttcttc ggttcgtcct
     1201 cgtccatttt cgataccgac agctagctta taacccaagg tatatcaaca taaaaaaata
     1261 aaaataggct atgacagcag cgtgacagca aaaaagatgg aaagttaaat atcaaacctc
     1321 gtaatttcat ttgcgagtgc ttgatttgtt tctggatata agtgtccata tttgtccaaa
     1381 gtagttttaa tagaggcatg acctagacgc ttagatattg catagatatt tttattatgt
     1441 tcaattaaaa aggcaacatg cgagtgtctt aatccatgca tatgaattgg ttttactcct
     1501 gcaatttcag ctagtttttt tattctgctt aaaatagttc ttggagatgg cggtaatcca
     1561 tcaaaagaaa aaaccaattc tatatttttc ccaattgatt gttgagtttt tttccatgtt
     1621 tttaaatctt caacggtttg tctgtctaac gaaattatcc gaatacttga tgtatttttt
     1681 gtttcagcaa attcataatc ttgtcttgta cggatgtaaa ttgacttatt tacgctacat
     1741 ctgccattta ttaagtcaaa gtctttccat tgtaacgcta agagctcctc actccttaca
     1801 cctgtaacaa aaataaaacg catcaaacgt ttataaaatt cttcataaaa atccccgtga
     1861 taaacactat tatatacttt cttaaattca tcaactgtcc aaaattctac ttgaggacgc
     1921 tgagttttta ttttacctat agtatctaca ggattttctt caataatttc aagtacaatt
     1981 gcccttttaa aaactactct caacttattg aatatctgtt taatataatt tggtgataat
     2041 ggttgctcaa tgcccttttt tacaacatgg attttcgata aaaactgttg aaattcctgt
     2101 atatgaattg gtcgaatctt tacaacctgc atttctccaa aaaaatccaa tgcacgttgt
     2161 aaaatatgat ctgttttcat atatgttttt tctacagttc ccaacttata ccaaggaaaa
     2221 aaatactctc gataaaaatc atgaaacgtt attccttgca gataaattcc ttgtgaatca
     2281 gaaaaacttt gttttaactc ttcgagtccc cttctagctt ctccttgagt tttgaagcct
     2341 cttctggtca cttgaattct ttttccaaag cgatcttgtc ctaaagttgc agaaaaaaac
     2401 caagtgcctc tttttctgtc tttataaaca ttcgcaattt tcctcatttt actattcctc
     2461 ccaagaaata tggagaactt cttctaaaat tgaaatagga attcttttta tttttgaatt
     2521 acgataaaaa aagtatcctt tctcaactaa aagttcttta cattccttga agattttatt
     2581 agcatagtac tgagaaaaac ctagattaat caaatctttt cgagtagctg ttttcattat
     2641 agcaccttcc ttactttttt tcatttattt ctatcagctg cttttgtcaa aagcacatag
     2701 gaatttcacc tctccccaag tttacggcga gccttacgga agtatcatta tcccaacttt
     2761 aaatcatcgc tttttattga ctataaaaat tattttagaa tatttatcgc tccttcttta
     2821 cagcaagaaa tcatggcgca actaaaatat gctccttaaa gtgttaacgt actgatagaa
     2881 tctatttaat tttcaatgaa caataggttt tctacctaaa agaatctact aattccttaa
     2941 ctattagaag attcttttaa acagaaaaag tggaaagggg atttttttaa ttagttaatt
     3001 ttaaatttta agatcgcttc tattaattta atttctagct gacttatcat atattcatct
     3061 acataggtaa cgaattgacc tacctcgtta aatccatttg tcaaacataa cttagccata
     3121 taagaatgat aatgtttgag tatcatcttg atcgaaattg gatctccttc tagagcagat
     3181 aagataatgg atagtggaac taataggtac tgccgctttt tagatttatc taccataggt
     3241 cataccccat tttcaattgt tcaactgcct tctttcgttg ataccagata ccacttgtgc
     3301 tcatattgag aattttaccg atttcagcat cattaaaacc tgcaaaataa taaagtagga
     3361 taatctttct tcttatctcc gataactgat caattgctgc tgataacttt tgatctgaaa
     3421 ttaatatttc cattccaaat aagaaataga catcttgttc atcaaaatga gtttgggaat
     3481 acctgccttc atttgaatct gccaatggtt cctcattatc ctttatgtta gcgtttcgtt
     3541 ttcgaataga cttagcttcg tttcgtaata cttttttaca gtaggcatca aattggtgtt
     3601 gtatagatat gtcattgtaa tgttgttgca tgataatatg ctcctttttc cccctttcca
     3661 ctaatacaac aatcagaaag cccctttttt tcgaaaaaac tagaaaaaaa acataaaaat
     3721 atttatcatt cttta
//
LOCUS       DAFLWC010000155         3724 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.161, whole genome shotgun sequence.
ACCESSION   DAFLWC010000155 DAFLWC010000000
VERSION     DAFLWC010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3724
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.161"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            127..579
                     /locus_tag="L1V17_002848"
     CDS             127..579
                     /locus_tag="L1V17_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237547.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            593..1282
                     /locus_tag="L1V17_002849"
     CDS             593..1282
                     /locus_tag="L1V17_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237548.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1407..>3724
                     /locus_tag="L1V17_002850"
     CDS             1407..>3724
                     /locus_tag="L1V17_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HBN1237549.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKI"
BASE COUNT         1258 a          489 c          772 g         1205 t
ORIGIN      
        1 attcctcctg ctatcttttt ctattattct atcttatttg atagtagatt taaaactttg
       61 caacagaacc aattatctta tcgtagatat atattataaa tttaataaga aagcgaggtg
      121 agaatcgtga aaaaaacgat actaagtatt ttttcagtat ttacaatatt aattgggggc
      181 tattttcttt tgaatttaga ttctgttaat tcaaacgctc aaataaaaga tcaaagagta
      241 gctgaacata ataataaaaa aatgagtttg accaaaaata tctattctat gtcagatgaa
      301 gaattgtata aagaatttgg tgatttatcc ggggaacagt tagaagaaag tattccagga
      361 attagtgact cagataaaat tgttgtcttg tctgctggtg ggcaattaat gggagatggc
      421 aaatccgaat tagttagtta taaacaaaat cacagacagt ttattgatgt taatactgat
      481 tccaacgcta tttcgattaa ggatctaaaa gagcttttaa atagtaaaag aaatgaatta
      541 aagcagataa aagaaactaa ttcagtggaa ttagagtaaa ggaagattca ttatgaaaaa
      601 gatttttggt gtttctgttg ggctacttat gatgttaaca tttggaaatg cagtatatgc
      661 tgctgagaaa gaagttattt cagatccaga gcagtacgcc tcacgatact ttgctgattt
      721 tgaagaagaa gataaagtac ttgcattgcc agaaggtggt tttttaaaag gggaagctaa
      781 aattgtatct atggataatc cagatataat tcaaggttca tataattcag aaactgatcc
      841 tgcttcagtt tcagtgacag aagcaaaaaa aattgttgct gaaaaattca aaaatgatat
      901 tgaaactact ccaattatgc ctcgaggagc atttccaccc gatgttggta ctagcggaca
      961 ccttcttgta ctagcaggag gaggaagcta taaatcacag ccatttagtg gtgcgggatg
     1021 gcgttttgga ggtatgggtg taaaaccagc tgatggtaca ggcaactttt tacgttggaa
     1081 atcctacatt gacgatggaa gagtaggaaa tgtaaatcaa gccaacgcaa ctaaatctgg
     1141 ttctattcaa ggaatggcat tgtatgctcg tgaaggattc aaatactttg caccaaacgg
     1201 gcctggttgg acaatgaata taggtattta ttacacttat aatcctgttg caggtacgta
     1261 ttatgttgtt caaaatattt aataaaacag cacaaagaga tttctttgtg ctgttttatt
     1321 atttttagtt gttgacaaac actaaaatat aaaatataat caacacataa acgaacgtat
     1381 gttcggcaag aaagcagggg atttttatgg atgagatggt tttaagtact cagaaatggc
     1441 taaacaagaa atacagtaat gttacagggt ttgataaggt tccagaaaat gggcgaacag
     1501 ggtggcctac aatctatgga cttattgaag gactacaagt agaacttggt attactaatc
     1561 tagtagctaa ttttggacct accactgaaa aaatgtacga taatcaggtt actcctaaat
     1621 ggggcaaaaa tctacctaaa aatattgtat ttcttattca aggtgccttt tggtgtaagg
     1681 ggattaatcc aggtggcttc gatggggtat atactccata tttagatact gctgtaaaag
     1741 agttgcagac tgatgcaggg tttaatggaa gcgctgtaac tggagttttg gatgcgaaat
     1801 gggccaaagc gttatttgat atgagtgctt ttgttcttgt tcccggcgga gatagtaaaa
     1861 ttagaaaaat gcagcaatgg ttaaatgtaa attatttaga atacacggga ataatgcctt
     1921 gtgatggtat ttatcaaaga aattcaaatc aagcattaat ttttgcatta caagctgaac
     1981 taggatattc tcccagtgaa gcaacagggt cttatggtaa tgggacaact agtaaaactt
     2041 atcctgtgtc tgaaggtaac tcgggaaact atgtaagaat aattcaatat ggattatatg
     2101 ttaatggtta ttttgaagac ggtacattcg atggtatttt cactaaatat atgggtttag
     2161 aagtactggc attccgaaaa tttatggtat tgcctgaata tactgaaata gcagatgttg
     2221 ttgtaataaa aggactattg tctagcgctg gagatattag aagatctgca gatggcgcag
     2281 atacttctac gcaattaact agatctcaaa tccaaacatt ggttgataat gatataaaaa
     2341 tagttggtag atatcttact ggtactgttg gaattggaaa agatgaacga aataagtatc
     2401 taactacaga ggaattgaat aatatttttt ctaaaaattt atctgtgttt cctatctatc
     2461 aagatggagg tgcagcatta gcttatttta cttatgatcg tggcttatca gatggtaaga
     2521 aggctataga tgcagcaaaa aatctaaata taccattaac aacagttatt tattttgctg
     2581 ttgatctaga catgttaggg gaagaaattc ttgcatatgc tggagaatat tttaaggggg
     2641 tatctgctgt aatgtcatat agcgggtatc aaacgggtgt ttacggaaca agaaatgttt
     2701 gttctcaaat aatcaataac gggtatgctt cgtttgcatt tgtttcagat atgtcgactg
     2761 gttatagtgg gaatttaggt tttcctatgc ctagacaatg gtcttttgat caatttgttg
     2821 aatttaccat aggaagtggc aacggagctg ttggtatcga tttaatcgct acatcgggta
     2881 gagatagcgg atttaatgag ttatcaaatg atactaataa tgataattac attgccaaat
     2941 acaatcagaa ggttataaat cagatggtac gtgcgtatca atatctatca caagctggtc
     3001 ttgataatcc ttggaaccct catttgacat tttatagata tgtaaattat tctggtttgt
     3061 catgggacat catttcttct cctgtaacag agcatgatag aaaaatttat gatgaatata
     3121 ggaataaatt aactaatagc gagggcctgt ataattattt tatagatcct aatactggtt
     3181 caataatagg tttgcctcac ttaattgtga cgttacaatc acagatgttt ctagccgaca
     3241 caatcaatga tagtgtttct gactttgcag gttggttagg agatttaatg acttgctggg
     3301 gtgaagttaa gaaattagga atacaaatgg agcaaggtgt atttgcatta gtaggtacgg
     3361 ctgcaggtgg aacatttagt ctagaagatt tataccaaga tgttgacgcg gtaaatgttt
     3421 ataccttagc aaaaagaaat tctgattcaa cagctttatc ggctttaaaa acgtactatt
     3481 gtgataaggg tgctattgat agatttaatc aatttgttaa gaacagattt ggttcttcag
     3541 ataaaatcgc ttcagtaaca aatagtttat tagaaaatga cgaaacagtt gatatcttag
     3601 gtgtagggat aatttcattt ttcattgata aaatagttaa taattcactt gggacagatt
     3661 ttacttatct tgattttatt ggagatgagg ggaaagttgc aaatggattt tctgaaaaaa
     3721 ttat
//
LOCUS       DAFLWC010000156         3722 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.162, whole genome shotgun sequence.
ACCESSION   DAFLWC010000156 DAFLWC010000000
VERSION     DAFLWC010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3722
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.162"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(193..810)
                     /locus_tag="L1V17_002851"
     CDS             complement(193..810)
                     /locus_tag="L1V17_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237550.1"
                     /translation="MGFQVLFGSLILTIVFLKWKTSNKKSMWSLVGIVLIIFTVTAAT
                     EANYSHKIQSYKGRLVMTKKDVTRYTSSRTGGLYDYAPLDALKYKDHLKKHEVKVGDR
                     WENASHKAYNSKIVYTVEDADEQNITLPVFNYWGTVVKVNGKKSTIENDNGLVSIKGT
                     GKRTIVEVSSTYPTTMILSLLISSITFIFLFTRYLIRCCGEMKID"
     gene            complement(872..1552)
                     /locus_tag="L1V17_002852"
                     /pseudo
     CDS             complement(872..1552)
                     /locus_tag="L1V17_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
     gene            complement(1874..2095)
                     /locus_tag="L1V17_002853"
     CDS             complement(1874..2095)
                     /locus_tag="L1V17_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237551.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            complement(2193..2438)
                     /locus_tag="L1V17_002854"
     CDS             complement(2193..2438)
                     /locus_tag="L1V17_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237552.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
     gene            2678..3292
                     /locus_tag="L1V17_002855"
                     /pseudo
     CDS             2678..3292
                     /locus_tag="L1V17_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
BASE COUNT         1189 a          676 c          547 g         1310 t
ORIGIN      
        1 atatgaaaag gaaaacgtag aaaattacgt ctacgttttc ctatttagtt ctatattttc
       61 attaaatttt atatttgctc ttttcacttt tcggaataaa ttcactgtga ctcttgatac
      121 cttcttttat atattgctaa tgtattttct ccattgctat gaaaatagaa tcaacatatt
      181 tataatatct atctaatcta ttttcatttc accgcagcat cttattaaat aacgtgtaaa
      241 taagaatata aaagttattg aactaattaa taaagataga atcatcgtag ttggatacgt
      301 agatgaaacc tcaactatag ttcttttccc cgtaccttta atagacacta aaccattgtc
      361 attttctata gtgctctttt tcccatttac tttcacaact gttccccaat aattgaatac
      421 aggtaatgtg atattttgct catcggcatc ttctactgta tagactattt tggaattata
      481 tgctttatga gatgcattct cccaccgatc accaactttt acttcatgtt tctttaaatg
      541 atctttatat ttcaatgcat ctaatggtgc atagtcatat aggcctccag ttcttgagga
      601 tgtataacgt gtaacatctt ttttggtcat aactaaacga cctttatacg actgaatttt
      661 atgcgaataa tttgcttctg ttgctgcagt cacagtaaaa ataataagaa ctattcctac
      721 aaggctccac atactttttt tgttgcttgt tttccacttt aaaaacacta tggttaagat
      781 taatgaacca aaaagcactt gaaaacccaa ggttctcggt tctgttgcga agtttgaaaa
      841 tcaaacgcgc cctctctgaa ctccaaatat cttaggctgt tattcccatt aataccttga
      901 tttcagtaga caccgaaaag ccgaagagcg ttccatttct tcggttcttt ttatatattc
      961 ctcgaatggt ctccatgccc ttaatcgtgg aagaggctgt acggagactt tgataaaatt
     1021 tatttcgtcg tttaataggt cgatggtctt gttctattaa attgttaaga tacttcacag
     1081 ttcggtgctc tgtcttagta tataaaccca cactctgtaa ctttctaaag gcggagccaa
     1141 gagaaggtgc tttatcggtc acaattgctt tcggctcacc aaactgttta tggagtcgtt
     1201 ttaagaaagc ataggctgct tgcgtatccc gtttctttcg taaccagata tctaaggtta
     1261 agccgtccgc atcaattgca cgataaagat aatgccaacg tcccttaatt ttgatatagg
     1321 tttcgtccat tttccatgaa tagaaggatt gtctattttt cttcttccaa agataataga
     1381 ggactttgct gtactcttat acccaacgat aaatcgtagt atgacaaaca tttattccac
     1441 gatcatataa caattcctga acttcacgat agcttagatt gtaacgcagg tagtaaccaa
     1501 cagcgacaat aatgacgtct tttttgaatt gtttgccttt aaaatgattc attactctgt
     1561 cctctctgtc ttttttctca attttacact aaaatagatt ttttggaaaa ctttgcaaca
     1621 gaaccgtttt tactatatac ttcttcccag aacttgtccg tctccttcaa attatctcta
     1681 cctctcgagt tcattgggtg gtttgcccat ttattaaaca tggaatcacc tttctcatac
     1741 tcatatattt atgtcctatt tcaattatat ttatatatgc ttaaataaat ttgtatcctg
     1801 aaatttattg taatatgaag ctgtatttta catatagtaa ccaaagagtt aataaaataa
     1861 aaagagcgaa ccattataga tcagctcttt tttcattgct gtttttaatc ttatctagaa
     1921 tcacttcaaa tgtttcaaag gtatttacat ctaactgaca taaccaaagc aagtacttct
     1981 tttctttgta agtccaatca atattacggt aagaggacat tagattatgg taccttgctc
     2041 tttgttcaac tgaagccaat tcccagcgtt tttcaaatat tttttcttct tccattattg
     2101 atccctcgca agacgctacc tcaaacttaa ataatgggca gcgaaagtct aattccttag
     2161 atctaagtat agcaaacaaa tatgaaaaaa acttagaagg tagtaaaagt tcttccgtct
     2221 tttgctttgc ttctattctt aatgtgtttc gttatcggtg ccctacaaag attttcatta
     2281 attacacact catttattgt tgtgtatttt ctgacatttc tctcttgatc aattatttta
     2341 attccatggg catcctgata gttcatagga gaggagcggc tatcagaaat agttgcacct
     2401 atctcttgaa cttcttttac aacttctgga aaatccatcc atcctgcttc agctgtcaaa
     2461 agtaataatc tataatattt atctttcctt ttcaatctaa gaaatcgtca ccccattctt
     2521 tttcttctat tataaactat ttaactttta gaattcaaaa accgtttgtc tatttagagt
     2581 ttaccctaaa tagacaaaaa tataacattg aaaaatttag agttctaacg tatgattagg
     2641 gtgtattata aacgttatag aaaagtaggg aataaatttg aaaattgctt atattagagt
     2701 ttcatccatc gatcaaaatg aacaacgtca aattgaagaa atgaaaaagt ttggcgctga
     2761 aaaaattttt atcgaaaaac aatctggagc gacgattagt catcggccga ttttccagga
     2821 agctttagat tttgtcagag agcaagatat ttttattgta gaagccattg atcgacttgg
     2881 acgcaattat gacgagatta tcgattcagt gaattatcta aagaagaaga atgtgcgact
     2941 tattatcacc agtttaccga tcatggctga agcaattgga aatcctctcc tagataaatt
     3001 catcaaagac ttaatcattt aaatctcagc catgattgct gaacaagaac gtactgaatc
     3061 gaaacgacgc caggcacaag gaattaaaat cgctaaagca aacggcgtct ataaaggtcg
     3121 tcctaagtta tacagtgcag acaccaaaga tcctcaacgt cgccttgtct ataggagtat
     3181 cgttcaggat cttgagaatg gggttgctat ctcaaagatt gcaacagact acaatgtgac
     3241 taggcaaaca atttaccgaa taaaaaaaga aatcgaccaa ctaattgtat gatttctttt
     3301 ttgaatcacg taattattaa ttagctttgt catcaataca gacaatcatt ttagattcat
     3361 ctagctaagt tgattacatt tatgttaaaa agaatttagt taacataaat ataattgatg
     3421 cataaatcgt ccttatttaa aggcatttaa cattgacaac ttagtataat gtatcttatg
     3481 taaactaata agatttgaat tttattttat acacactcga taatagatca attttatggt
     3541 cccccgcatt tacgattgca caagagaaac ataaagtcga cctattagca tttcttttca
     3601 attcaaacat taaaaaagtt tatacctctg ctactaaaaa atgaaattat ctatttaaaa
     3661 tttaaaacgg taaatctgat tcatccaaat tggaaaatgg atcagcctgt attggagctt
     3721 tg
//
LOCUS       DAFLWC010000157         3718 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.163, whole genome shotgun sequence.
ACCESSION   DAFLWC010000157 DAFLWC010000000
VERSION     DAFLWC010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3718
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.163"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..353)
                     /locus_tag="L1V17_002856"
     CDS             complement(<1..353)
                     /locus_tag="L1V17_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237553.1"
                     /translation="MKKFKKKIYLGLVVGVSMFGFMAHTKQVTADTNQKERIMSQLDD
                     SQIEYVPNELIVSLKATQRISTEKNKPQNLLGVKVMVEKDLTLRINESDYNKRDQVLL
                     VKLNEEISVEEAVRT"
     gene            complement(613..1161)
                     /locus_tag="L1V17_002857"
     CDS             complement(613..1161)
                     /locus_tag="L1V17_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237554.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(1162..2019)
                     /locus_tag="L1V17_002858"
     CDS             complement(1162..2019)
                     /locus_tag="L1V17_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBN1237555.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            complement(2305..2591)
                     /locus_tag="L1V17_002859"
                     /pseudo
     CDS             complement(2305..2591)
                     /locus_tag="L1V17_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(2581..2910)
                     /locus_tag="L1V17_002860"
     CDS             complement(2581..2910)
                     /locus_tag="L1V17_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBN1237556.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            complement(2987..3259)
                     /locus_tag="L1V17_002861"
     CDS             complement(2987..3259)
                     /locus_tag="L1V17_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBN1237557.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            complement(3259..3522)
                     /locus_tag="L1V17_002862"
     CDS             complement(3259..3522)
                     /locus_tag="L1V17_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBN1237558.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
BASE COUNT         1091 a          754 c          473 g         1400 t
ORIGIN      
        1 aatgttctta ctgcctcttc cacactaatt tcttcgttca atttcactaa taatacttga
       61 tctcgcttat tataatcgct ttcatttatc ctaagagtca aatctttttc caccataact
      121 tttacaccca ataaattttg cggtttattt ttctctgttg aaattctttg tgtagccttt
      181 aaactgacaa ttagctcatt gggtacatac tctatttgag agtcatctaa ttggctcata
      241 atcctttctt tttggttagt atctgcagtt acttgtttag tatgagccat gaacccaaac
      301 atactcaccc caacaaccaa tcctaaatat attttctttt taaacttttt catctacatc
      361 tcctcctaat agttttattt tagagttagc tctattactt atttactaac tcaacaacag
      421 attatcatac acttgttaat gaaatcacaa tatctcatta aaacacaccc taaaatcata
      481 accgttccta tgctcatttt ttggattttt taatcacgta accagaaaaa taaatcccct
      541 ctatttcacg caaatcaaag aagaactaag taactaccgt ttaaaggtag ttacttagtt
      601 cttctttgat tattatctaa ctttattatt cattccccac cctttgcgca gtgagtcttc
      661 ggtatcttgt tttatctgac tggtagttct tattatttct ccacgatcat ctaattctgg
      721 aacaattgga tatttttctc tgaacaagtc tagttctttc accacgtcat taaacaaatc
      781 ttgcttatct tcttgcgtaa gattctgttt aatatactca tctaaagctt ttctaagcaa
      841 ttcatctctt gtcatattag tctcatactt ttctactaaa actctggaag tcgcatttaa
      901 caaagtcgac agttttaaag gatgcttggt ggaataaacc ttatcaaact ttctgattgg
      961 tgcgccaact ttttttgttc ttcctctact ctgtctttca acattggagg aagtttttat
     1021 ttcttgaact tggtgcactt ctaattgctt attttcagat ggtgtaattg cttgctgctt
     1081 tttctttgct tctgcttctt tttttatttt ggcgagtcct ttgttgttcc caaaaatatc
     1141 aagtcctttg atgtcagcca attactccac ctccgcatac caattctcgt gttcttccaa
     1201 ttctttcaaa atactgataa ataattcgtg gcttttgcga tcccattgtt ttaagagacc
     1261 tttctttgtc ttctccatcg taatacctga tccgtcgtat cgttttaagc gcgcattttt
     1321 gagtacaaca tttttaatca aatgttcccc ataaatctct tgggcttgtt tatacatttc
     1381 ctgatctact gcgtcaccgc tttccaacat gaaaggaata acaccagcaa catataaatt
     1441 tgtatcaaat tctttcacaa aaaagtccat atactcaaga tattgcatcg catttctcat
     1501 cgattttact tgggtctgta agacgacgat tgcccaatcc gcaatgtaca tcgcggattt
     1561 actatataca gaaatagaag gtgggacatc taaatagatg acgtcaaact catcaaataa
     1621 tggttctagc ttttctttca tatatttgaa ttgggataat gaatcattat attggtcttt
     1681 gatccaatca tcatacattt caaaggacat gtctgctgga agtatataga ggttattgat
     1741 tactttatag acagcctctt taggtggaag attgtttatc aacacgtcag tcacagtatt
     1801 ttcgtaaaca atcggttcac cttctccgcc tccttcttcg ttagtgaagt tcatatgcgt
     1861 taagttcatc acatcagaag tatttccttg catatccaag tcaattatca aggttctttt
     1921 tccttcatta actgctgatt caaaccctaa catttgcgcg cacgtacttt tacctacgcc
     1981 acctttaaaa ttaccgatta catatttctt cgctaccacg ttcctacctc ttttctttta
     2041 gcaatattca tttgatacta ttataacata tttattttta gttactacca aaaaaaagat
     2101 atatatgtac taccttataa ttaataagta aaaggtagta cataaataag gaaaagctga
     2161 aatatattga tttatagctt tcctcaaagt aatgacgtta tttaatttat cgagaagcag
     2221 agaatactcg cgactttagt catgtagacg aatcagattt tcgataaaaa agaagccgtc
     2281 cttcttaaga acgacaacaa atcactagat taattttttc aactgttcat aaaagttttc
     2341 atgcgttcca cataacaata ctggaataac cttgttttct ataatctcgt aagctactct
     2401 atatgttgtg cccgcatatt tgaacccact agaccaaata cctgataaat ccccagtttt
     2461 ttgttcaccc ttatatggat caatcgcaat ttcatcataa attaaattca aaaatttttc
     2521 tttcaatggc ttctctttta gctttttaaa tacttaatga catgttttga aggaacgatt
     2581 tcataagcca atttctgttg ccaactcctc tttagtcatt actttagaat tagtaagtgt
     2641 atcttcagca atatctctaa aggaagaatg cattttgttt tttctattct taaattctac
     2701 aagaatctca tctttatcgt agccttctgc aattatatca gacaaaatat cttcgctaaa
     2761 atcataaaat tctttttgtg gttcaacaaa ttcataaaga ataccattct ctaccaactt
     2821 tgcttcaact tcgactccat taggaacatt aaaatcttta ggtactgtca acatgattga
     2881 attgccttgt tttcttgttt ttgtaatcat ttaaatccct catttctaac agtatgtaat
     2941 tacttagtaa atacattata ccacgagata atgtatttac aagtaattac tgtgactcgt
     3001 aatgcgtcct tgctgaataa atttcaacca cgtgttcatc ttcatctacc ttataaacaa
     3061 cccggtgttg tctattcaat cttctagaat acctaccttc atgtgtaggt tttaacttct
     3121 caaatgattg ggtagggaga tagggatctt cctttaaagt ctgaataacc ttctcaaatt
     3181 gaggtttcaa attagactgt ttgattttct ttaaatcagc tttagccgag tttttaatca
     3241 tcacagaata gttattcatt ataagttatc ccaatcaatt tcatcaacat tagtaaatcc
     3301 actatcatct ttttctcgct tacgaacaac acccaaagtg cctatttgct caagtaatag
     3361 cgtttctttg attgctttcc aatcatccaa accaataagc accgcattat tttcactgcg
     3421 ctcactaatg atttcaattt ccgtatgatt ctcatttaca tctttcaaca acttataaaa
     3481 atttttccgt gctgagctag gatttaagac tgtttttgcc atatctactc cccctctaat
     3541 ttatatctcc attctaacgt acttaattaa gtacgtaaat tcgattgttt tgtttaaatt
     3601 ggagtaccaa aacagcattg taaagtgtta tccgtttcct ttatacccgt ggtgctagtt
     3661 aattttttcc tagaggaaaa tgtctaaaca tgttggtaaa tcaacaaaaa aacgcata
//
LOCUS       DAFLWC010000158         3677 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.164, whole genome shotgun sequence.
ACCESSION   DAFLWC010000158 DAFLWC010000000
VERSION     DAFLWC010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3677
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.164"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            64..972
                     /locus_tag="L1V17_002863"
     CDS             64..972
                     /locus_tag="L1V17_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HBN1237559.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKINYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FERWRQEQEHSFQDWREGQESDYLAWFESIKDILKTIDPGGVMLAELTDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVAFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            972..1592
                     /locus_tag="L1V17_002864"
     CDS             972..1592
                     /locus_tag="L1V17_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237560.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            1596..2045
                     /locus_tag="L1V17_002865"
     CDS             1596..2045
                     /locus_tag="L1V17_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237561.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKVKLDGLANITFEKVGTV"
     gene            2045..2539
                     /locus_tag="L1V17_002866"
     CDS             2045..2539
                     /locus_tag="L1V17_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237562.1"
                     /translation="MADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     DSVILTVPEGYRTPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSAYSFVI
                     TYSI"
     gene            2553..2984
                     /locus_tag="L1V17_002867"
     CDS             2553..2984
                     /locus_tag="L1V17_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237563.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            2986..3123
                     /locus_tag="L1V17_002868"
     CDS             2986..3123
                     /locus_tag="L1V17_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBN1237564.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFVPLCITDEEADKIINKDKSA
                     S"
     gene            3160..3453
                     /locus_tag="L1V17_002869"
     CDS             3160..3453
                     /locus_tag="L1V17_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237565.1"
                     /translation="MINLGEWGMIAGSITAIVSLILLVIRPIAASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERRK"
     gene            3450..3674
                     /locus_tag="L1V17_002870"
     CDS             3450..3674
                     /locus_tag="L1V17_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBN1237566.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
BASE COUNT         1324 a          546 c          814 g          993 t
ORIGIN      
        1 cagtattata gtgcaagtgc aatttcttcc attgtcatac caccaaaata gggaggtgat
       61 ttaatggcaa agtggaatgt catattaagt acaacagaac cctataatta cgtggggatg
      121 attcaagttc gacaaggcaa taagaataca gaggttatgg aagcgactat agttgaaaat
      181 ggtcttccct acgatttatc agaatgtaag gtatattttg aatcagttgt aggtgggaaa
      241 tatccagtcc aattagaaac aaaaattgtg gatgctaaaa aagggaaaat taactatatt
      301 tttgataaat attccatgca gtgtttacat cgacaaacag ccaatttcat tatatttaaa
      361 ggagaagact tgattggaac aactcaagac ttctcttatt ttgtcattaa tgctgtttca
      421 aaaacagaag gagaaatggg ttcttattgg caatcaatcg aagatttaat tgcggatatg
      481 acggacttta ttaatgaaaa taaaggcgat tttacggact ggatgaatga aaggaaagaa
      541 gaatttgaac gttggagaca agaacaggaa cacagtttcc aagattggag agaaggacaa
      601 gaatcagact atttggcatg gtttgaatca atcaaggata ttttaaagac gattgatcca
      661 ggtggagtca tgttagccga actaacggat gcgcgagtag atattcaagg agttcgtcat
      721 gcgtctattt cagagcgttt gctggcagat atggactatt tatatcagaa attgcgagca
      781 acgcttttca cgattgaata cggggagatt gaagtgactg atattttgca ggatgatctc
      841 ttttcagata atcatgaagt cgaaaaagtt ggaactgtag cattcccgat tgaagaagga
      901 gccttgatca tcgcaaccgt tgatgatcca aagcaaaatg tgttcactct tgagaaagtt
      961 ggggtgatct aatggctaaa actaaacgaa tgatggaaac ggatgaaaaa acgggtgtac
     1021 aacgccaatt ctttccaatc acacatgctt ccgcagttct tgggttagaa gaaataatag
     1081 caggagaagc aacagtttta tctgttaatg gaaaaattgg agccgtcgtc attactaaag
     1141 aagatttggg attagagaat gttctcacag aattacccta tgcaagtgaa gaagatgacg
     1201 gcattatcac ggcagaaatg tatcaaaaaa ttttaaacag tggagaaggt gactacgtgt
     1261 tgccagttgc cactatcgac cgtttgggtg gcataaaagt tggtgaatta ttgacgattg
     1321 atgagacagg gaaagtctct gcagtcagac aatctgatgt caatttttcg ctggagttaa
     1381 aagaaaaact cgattcactg aaaaattata ctgctggaga aaacatcact attgatgaag
     1441 atggaacaat tagttctaca ggtggtagtg ggactggtgg tgtcaatcag tcatatgtag
     1501 atcaaaaatt ccaagaagct gtaaatcaag cagaaaatta cacaaacgaa agaattccaa
     1561 attttacttt tgaaaaaatt ggggaggtat agagaatgac agatatcgta aaaataaaac
     1621 aaagcaatgt acaggtttat ccacaaactc attggaatgc tatagaaggc aaaccaacaa
     1681 cggtgaaggg agataaaggc gatcctggcc aagcagcaac aattaccata ggaaccgttt
     1741 ctagtggttc aaccgcttct gttacgaatg taggaacatc atctgcagct agatttaatt
     1801 ttgttttacc aaagggagat aaaggtgatc ctggaataaa tgccacaact acagctgtag
     1861 ctacaactac agcaaatggg ttgatgtcgt ccacagataa aactaagttg gatggaattg
     1921 cagctggagc acagaaaaat ccaggtaatg ctacaactac gacagcaggt ttaatgtcag
     1981 caaccgataa agtgaaactt gatggattag cgaatattac atttgagaaa gtggggacgg
     2041 tttaatggct gatattgttc aattaaaaga agacggagtt gctaaatact taaaaacgca
     2101 tgtagaagct attgatggta aagaagcatt ggtgcagaca gatggagacc aagccattgc
     2161 aggacataag aatttttcag gttctgtaac aatcaataat aaacgtgttt tgacgactga
     2221 tgataacaga tatgaagtgg taaatctggt tgtcactaac ggtaatacag ggacagcaaa
     2281 gctttatcgt gaaggaaaaa cagtttctat atattttgtg gctttaaacg gaaaaagtag
     2341 tggcgggaat gattcggtta ttttaactgt tccagaaggc tatcggacac caattagttt
     2401 tgaacaactg gttgggtcaa tagaccgttc tactttgaac agtgctcaac tatctattgg
     2461 cgcagacgga gccattaaat ggagaagaaa ttcaagttat ggatcagctt attcatttgt
     2521 tatcacttat tcaatttaag ggaggaaatc taatgaaagt agtttacaaa tcaatcaagc
     2581 cttacggatt cgagcaaatc attttgaaca atcaagaaaa tatccctgaa aactgtacag
     2641 agattaaacc accagttcct aactggagac caagatttga ttttgataaa aaacagtggg
     2701 ttgagttagc tactgaagaa gagaaaaaag ggaatgctgt tgatagcgta gatgaattgg
     2761 ctaatattaa ggcattatac gaaacgctga aggcagaaaa tgatgaattg aaacagctaa
     2821 attctaaagc aatgctaaac aatgtagcaa tcaagcaaga aaatgtctta ttgaaagaaa
     2881 agtcagaaag tttagcgcag ttgaattcaa aaacgatgct tgcttctgta caaaatacca
     2941 aggaaatcga agaaatcaaa aaacaattac aaggtgggaa gtaacatgta ttcatatgaa
     3001 gatatcaaac taatgtatga ctggggctgt ttcactaacg aacaagtaat ggttttcgtt
     3061 ccattatgca ttacagacga agaagcagat aaaatcatta ataaagataa gagcgcatct
     3121 taattgatgc gtttttattt aaggtaaagg agttgtcaca tgattaattt aggggaatgg
     3181 ggaatgatag caggatcaat aaccgctatc gtttctttga ttttattagt aattagaccg
     3241 attgctgcat ctttctcgaa aattactgag actctttcaa aagtaagcca caatttagat
     3301 ttgctgacta aagatttaga atcgagcaaa tcagatcgat tgatgattca tgaagaacta
     3361 aagaaacacg atgaaagatt agatacacat acagaaaaat tggtggaaca cacgcaacaa
     3421 atcaaaactt tgtttaggga gagaagaaaa tgaataataa aacgttcgaa gtactaaaat
     3481 ggttcgcact ggtaattatt cccgcactag ctactttcgt ggggttagtt ggtaaagcgc
     3541 tcaattggca gtacacagat atctgtgttg tcatcattac tggttttggc gcgtttttag
     3601 ggagtgtgtt gggtgtatca aatcgaacct acaaaatgtt ctcggctgaa agcgaagaag
     3661 gaggaaacaa atgaaaa
//
LOCUS       DAFLWC010000159         3566 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.165, whole genome shotgun sequence.
ACCESSION   DAFLWC010000159 DAFLWC010000000
VERSION     DAFLWC010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3566
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.165"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            142..1881
                     /gene="yfcC"
                     /locus_tag="L1V17_002871"
     CDS             142..1881
                     /gene="yfcC"
                     /locus_tag="L1V17_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBN1237567.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            2038..3222
                     /gene="iadA"
                     /locus_tag="L1V17_002872"
     CDS             2038..3222
                     /gene="iadA"
                     /locus_tag="L1V17_002872"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HBN1237568.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            3333..3536
                     /locus_tag="L1V17_002873"
     CDS             3333..3536
                     /locus_tag="L1V17_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBN1237569.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
BASE COUNT         1142 a          592 c          826 g         1006 t
ORIGIN      
        1 ataggagaaa aaaaacaaaa tagaaaaaag tgattttcta ataaattatt catgtggaaa
       61 tgtcattttt actgtataat tcatttgatt atccattttt tattcatcaa aattactgaa
      121 aaaagaaagg aagaaataaa tttgaagaaa acaaattctt caggaaaacc gaaacgcgac
      181 ttcactaaat tatcgacacc ccatacgtat gtcattattt ttggtgtagt catctttgca
      241 tggatactga cttttgtcgt tccagcagga aagttcagca cgcaagatat tgaatacaaa
      301 gatgcaaatg gcgaaacaag tactcgtact gttttacgtc aagattcctt ccgttatgct
      361 tacgagctgg ataagtcgta tgtgtttgat caattagaag aactgcaaga tcatccagca
      421 gaacgtgaaa aactggatgt tccggaaaaa ggattggaaa aagtcattgc tgacggagaa
      481 aaaaatctta cgcaggaaaa actagatgaa atctccttga cagatgatgt gctttacgat
      541 cagtacggcg aaaatatcta tgatacttct aaaaaattgc ataaaacagc caaaatatgg
      601 ggaacagatg attttggcgg ctttggtttc ttaaattttg tttttgaagg actagtatct
      661 ggagataagt atggatctgc tgtagggatc gctgcattga tccttgttgt tggaggtgct
      721 tttggtatta ttatgcgtac cggagcgatc gacgcaggta tctatgcgtt tatcagtaaa
      781 actaagggac tggagcgttt agctttaccg ctattattct ttgctttttc attcggtggc
      841 gctacattcg ggatggcaga agaggtaatt ccattctcaa tggtgatggt tccatttgtc
      901 attgcgttag gatatgactc gatcgtagca gtaaccgtga cttatgtcgc atctcaagtc
      961 ggaaatgcga cctcttggat gagcccgttt agcgtagcgg tggctcaagg gattgctgga
     1021 atccccgtgt tgtctggtgc gacattccga ttgattatgt gggtagttgt tactgcatta
     1081 gccgctggtt atatgatgat atatgcagaa aaaatccgta aaaaaccaga aagttcgttg
     1141 acttacaaat cagatgatta tttccgttct catatcaaaa agacatctga tgaaaataaa
     1201 aaattcatgc ttgggcataa attgatctta ttagagatgt tagttgtcct tgtctggatc
     1261 gtttggggcg tgactcaaaa aggctattac attccagaaa tcgcttctca attctttgtg
     1321 atgggattag ttgctggaat cattgctgtt cttttcaaat tagatggaat gaaagtcaat
     1381 gacatcgctt cttctttcca atctggtgca gctgatttag ctggtacagc aatcgtagta
     1441 ggtatggcca aagggattct tcttgtcttg ggaggatctg atgcatctgt tccttcagct
     1501 ttgaatacga ttttgcatgg gatcgggacg gcgttgaccg gtgttccagc tgtcattggt
     1561 gcttgggcga tgtacatctt ccaaagtttg ttcaacttgg ttgttacatc aaattcagga
     1621 caagcagctt tgactatgcc aatcatggct ccactggcag atttagtagg tgtatccaga
     1681 caagtagcag ttcttgctta tcagcttggt tcaggtttta tggacgcttt tacacccgta
     1741 tcagccagct tgattggtgt gctaggtgtt gcacggatcg aatgggcaaa atgggcaaga
     1801 ttccaaatca agatgcaagg attcctgttt gttttaggaa ctattttcat catgattgcc
     1861 attgcaatag gtctgcagta gtactggaga cctgtaaata aaaaagtaat ccaaacagta
     1921 gataaggact ccaagaaccg tcattttacg gtaaaatcaa aggagtaaag atcctatcgt
     1981 ttggattatt ttttaagatc ctatcatcag ttatacttaa agaaagagga aaaatgtatg
     2041 aaaatcattc gacaaattga agtgtttgca ccagattact taggaaaaat ggatgtactg
     2101 attgccggtg ggaagatttt ggctgtagaa gaacagctag aaggcggcta cgaaggagtg
     2161 gaagtagaag aactttcagg tgagggaaaa gtactaaccc cgggtttcat tgactgtcat
     2221 ttccatattt taggtggagg aggagaaggc ggttatcaaa atcgaacgcc agaagtcaca
     2281 ttgagccaat tgactacagc tggtgtaacg acagttgtcg gttgtttggg aacagacgga
     2341 gaaggtagag atatgactgc gttgatcagc aaagcgaaag gtctggaagc agaaggaatc
     2401 tccacttatg tatacgaagg ttcgtaccga ttgccggtaa aaacagtaac agattctatc
     2461 atcaaagact ttttgacaat tgataaaatt atcggaatcg gagaaatcgc agtatccgat
     2521 caccgttctt ctcagccaag ttttgaagag ttcgctcgtg cagtagcaga tgctcgtgta
     2581 ggaggcatgt tatccggaaa agctgggatc atcaatgtcc acttaggcgg aggaaaaaga
     2641 aagctagagc tattgacacg aatcgtagaa gaaacagaaa ttccgatcac acaatttttg
     2701 cctactcatg caaatcgcac accagaatta tttgaagctt gcgtggcatt tgccaaacgt
     2761 ggtggcacga ttgacttcac tgctagcgaa gatcctgatt tttgggagaa gacagatggt
     2821 gaagttcgct tcagcaaagc actgaaacga ttgatcgagg aagatgtttc tttagataat
     2881 ttcacgatga cctcagatgg acaaggaagc ttgccttatt ttgatgaaaa caatcatttc
     2941 ctagggttag gagtaggaag tgccaaggca ttgctagtag ggatcaaaga agctgtgcaa
     3001 aaagaaagta tccctttgga aatcgcctta cgagctataa ccagtaatcc agcacgtata
     3061 ttgaaattgg ataaaaaagg aaaaatcgaa attggtgctg atgcagatct gtgtatcttg
     3121 gataaagaaa cgcttgatat tgatacagtt atcgctaaag gagaaataat ggtccaagaa
     3181 aaagaagtca aagtatgggg gactttcgaa aaaagttttt aatcaacagc tctaactatc
     3241 ttttttagaa aacgagcgtt ctgtttgtct gtatctgttg ttgatgttac cctgaaggta
     3301 gatcaataaa caaactaaga ggaggaagca caatggcaga tttaaaagga cgttctaaag
     3361 atatgaaaga taaagtagtc ggtgaaggaa aagaagcata cggcaaagca acagacgaca
     3421 agagcaaaga aacagaaggg aaagcacaat cactaggtgc tgacatcaaa gaaaaagctc
     3481 gaaatttagg cgacgaagtc aaagacaagt tttctcgaaa agacgaaaaa aaataaaaac
     3541 cacttattac taattgaatc aagcaa
//
LOCUS       DAFLWC010000160         3463 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.166, whole genome shotgun sequence.
ACCESSION   DAFLWC010000160 DAFLWC010000000
VERSION     DAFLWC010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3463
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.166"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..2232)
                     /locus_tag="L1V17_002874"
     CDS             complement(<1..2232)
                     /locus_tag="L1V17_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237570.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
     gene            complement(2904..3172)
                     /locus_tag="L1V17_002875"
                     /pseudo
     CDS             complement(2904..3172)
                     /locus_tag="L1V17_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT          971 a          766 c          549 g         1177 t
ORIGIN      
        1 accggtttgt agcgtttctc cttctcggtt ctgtaactca aaaacagctc cttgaaggac
       61 ttcaccactg ccttcagcat gtttaattag ttcaacacca cccgtatcaa ggatgttttc
      121 aatggttaac gtcacttctt ctatggagta ttcatttata aaaacatcat gtaccgtcgc
      181 atctaaaaga tacccttccg gtgcttctgt ttctcggact tgatagctac ctacaggaag
      241 cggttcactt aaaaattctc cgttttctgc cgttatacct tcttgtatca cttgtgaatc
      301 gcttgataaa atttcaaatt ttgctcctgc cagcctttgg ccattctcat cagttttaat
      361 tactttaata cgcccatcga ttttccttgt tcttacagta ctcgtattca atcgattgtc
      421 actattcaca agcgttgcaa agtttaaaat ttgatcgccg accgcatacg cctctacatt
      481 gaccttaaaa gagagggtaa aacttgtcgg accaccaatc gtattattcg cactgaaacg
      541 aactattcca ttattgactt cggcatcaat gaaagaggga atatctgata gaaatgacac
      601 aaattccatg ccttcttcca aaacatcttc aataacaagc gtatttcttg ttccagaaaa
      661 catcgagaca tgcagagtat acgttagttc attttcattg agattgataa catttttgtc
      721 cacacttttt cttaaagaga ttgccggaag attactttca gggattctca agcggtagtc
      781 tcggctcatt acctgattat tgtaggtcat actcgctcga ttccgagaaa acccatcctc
      841 ttgtcttcct tcattgaaca agtcgacatc ggtcacttca agagcatatt caataaaata
      901 cgattgaccc tctgctagat taccaaagtc cacaacaagt gtattcgttt ccttattaaa
      961 agatactttg tccacaaatt cctcggaaac ataatgagtt ctaacgtttg cttcacctgg
     1021 attcgttact tctgcgatcc gaaccccacc tgaaataggt tctctatttc cagtggaact
     1081 ccatgtagtc ggattcggtg ccaaagttgt tccttgcggt agtacatcgg taaccactac
     1141 accgtctttt cgtgatcctt cataatttac ctgcaaaata aatttattac tgttggtcac
     1201 gtcttgcccg tcaatcagca gattcccaag atttccttgg ctgtcgattt ctctagagcc
     1261 atagtataat ttcgaaaaaa tgggtcttga tgaaggaata ggcgtaattg aaaattccgt
     1321 gtttgctgct cgctcagcat aagtaagact cacttgaaag tcattatttg gctcagtacc
     1381 gcctgattga aagaaagcaa cttcaaacgt gatactgaat gtatacgact gagcggcttc
     1441 atttaatcct tcataatcaa aggtaaatgg aaaaacaacg tctgtgcctt cttggtaaaa
     1501 tgccagtggc tttaaaggtg aatcatcagc gacctccact ctaatgaact caattaagcc
     1561 aatcgatgct ctaggaactc gtacgaccat ctccccatat tcttcaagaa tatcgccagc
     1621 gcctccttga atgtatccct ttaacgtttg tgtatgcctg ctcggcaaag tggggcgctc
     1681 agcagagatg ccgatgtcat aattcaagag ctcctcttgt ctttcaatct gagattcctg
     1741 cgttatagat ggctcagatg atctggcttc attaaaagat tcacttaagc tttcttctgg
     1801 tatattaaaa gattcacttg tgctttcttc tggtacatta aaagactcac ttgtgctttc
     1861 ttctggtaca ctgatttcta ttgagaccgt atttgattga atatcaccgc ttcttgcggt
     1921 caattcgtat ttacctgaat gctgggaaga ataagtaatc agacgttcgt aatcattgag
     1981 ttgcttcact tccccttcaa tcaaatcctc actcttatca atgaccaatg catttagcag
     2041 gtctggtgtt cctctgactc gcaactggaa ctgctcaccc aaagcagcct cctcttgatc
     2101 aacttcgatc gtcagcgaac gctctggctg ttctgctaaa gactcagcta gaaccgttat
     2161 gttcccaaat tgattgatca caataagcat aactagaaac atacttaaca gtttatgaaa
     2221 tttgttcctc actattactc ccccttataa ttttgactaa acaacaaggt acccgataat
     2281 tttctaaaaa gattccccaa ctcaaaatgg ctgcgttacc tccctcgtat tttcggttca
     2341 actcaagcgt tgcaatgtaa gctgtaaaca aagctaatga ttgccgattg tcttctgttg
     2401 attgattcga tagctttgta tgacttttag ttgtccgtgt ggcttaacca taattatgat
     2461 ttcacgattc ctcctgccag tgccttgcac aagctggagc gtaaccctaa tagttatttt
     2521 gttaatgtac ttatatactt ttatactttt ccattagaaa caatcactaa atcgttgata
     2581 ccaaggtcag actctagaat ttcatcagtg agtccctgta ttggttaacc ttcatcaatc
     2641 ccaaaaaaat atatcaatgc ttagcatcaa aatgaatata tagtttagaa tacttgggat
     2701 tcatcgataa ctgatcgctt atttggccat attatttggc acttggttca actaaacgca
     2761 tttaggatgt tccttcattc tcgtcatgga tgttctcaaa ccgtcattac taataaactg
     2821 tccaccgaat cgatggttca tttcttgcat tttccacgtc caattactct ttttgctctt
     2881 tatttgggcg tagtttcact ttcttaactt gtatcgtctt ccatcaactc cttaatcatc
     2941 ttcttagctt tattggctcg gtttccttgt aaaaggtatc tacaaatagt gacaatctgt
     3001 attaaatctt catcattttc tgtaatgtca ataatttcta tattctgtac catatattgc
     3061 aaagggtttc actaagttca taaccgaagc gaattaaaca acttttgtat agaataacta
     3121 ccttttctat ttttccattg gtaattctat ctattaattg gtttaatcct tttgttgtag
     3181 ttgattccac taccaagatg attctctcga attttaaagc ttgaagatgt attgctattt
     3241 ttgctaactg gcgtatttgc aactattttt cccttctatt cttccttcat tgattcccct
     3301 ctaaaattac tatccataaa aaattgcata aatgacaata gtatttatat tagtcatact
     3361 gctttttaac acagcaaatt ccagaaaaac attcgttaca tatttgtgaa tttttccaaa
     3421 aaataacatt tttataaaac gacgaaaaat aaatcactac cag
//
LOCUS       DAFLWC010000161         3307 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.167, whole genome shotgun sequence.
ACCESSION   DAFLWC010000161 DAFLWC010000000
VERSION     DAFLWC010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3307
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.167"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..705
                     /locus_tag="L1V17_002876"
     CDS             <1..705
                     /locus_tag="L1V17_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBN1237571.1"
                     /translation="DIKKNTKVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHP
                     TSVKYYDEIANSLTEALYSTIRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLE
                     NMFLRVGVQAKAVLDPHFQAQVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKI
                     IAITNYIHSPIGKSADLVLQTAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSV
                     ELREKVLRSIIDKSIE"
     gene            complement(1388..1486)
                     /locus_tag="L1V17_002877"
                     /pseudo
     CDS             complement(1388..1486)
                     /locus_tag="L1V17_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(1751..2206)
                     /gene="tnpA"
                     /locus_tag="L1V17_002878"
     CDS             complement(1751..2206)
                     /gene="tnpA"
                     /locus_tag="L1V17_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBN1237572.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            2449..3307
                     /locus_tag="L1V17_002879"
                     /pseudo
     CDS             2449..3307
                     /locus_tag="L1V17_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT         1091 a          576 c          577 g         1063 t
ORIGIN      
        1 gatattaaga aaaacacaaa agttggcgat gctactatta ttcgcttttg tcaaaaaatt
       61 ggtttttctg gtttttctga tttaaaaatt gaaattgcaa aggaagactt tagtcaaaaa
      121 aaagaacatc cgactagtgt aaagtactat gatgaaattg ctaatagttt aacagaagct
      181 ctctattcca ctattaggct tttagacgaa gaaaaattga atgaagccat taaaatgatc
      241 actcaatcaa aaaacatata tatatttgga gtgggatcta gtggaaatac tagtcttgat
      301 ttagaaaata tgtttcttcg cgtaggagtt caagcaaaag ctgtactaga ccctcatttt
      361 caagcccaag tcgcttcttt attaacagtt aatgatttag taatcatttt ttctttatct
      421 gggaaaacga aagatactta tgattcattg aaaatagcta aaaaaaatgg cgcaaaaatt
      481 attgctataa ctaactatat tcattcacct ataggaaagt ctgcagactt agttttacaa
      541 acagccattg aagaatttct taatggtgga tctttagctg gaaaaatatc acaactttat
      601 atttgtgatc tattagttca tggttatgaa caaaacaata atattgattc agttgaatta
      661 agagaaaaag ttttgcgctc tattattgat aaaagtattg agtgaactac ccccacttag
      721 ctaaacctaa cggtttttaa cgattgaagt aggcaattct tgggatgaga gcatacttga
      781 tagcttattt tttactaata gcggtggctc ttattgacca aatatccctg tagttcctac
      841 ggttcttgat tttatctaaa gatattttta tcgtggaagc tattgatcaa cttgaaagaa
      901 aaacgtgtag ctcattatca ctagtttatc gagtatggat gaagcaatgg atcatcctct
      961 cttaaataaa tttattaagg atctgatcct tcaaattttt tccatgatcg atgagcagga
     1021 acctactgaa tctaaacgac atcgggcaca aggaattatt aagattgcta agcgaatgtt
     1081 ttctataaag ggtgttctaa gctatacagt gttaattcaa aagattccca atcatcttgt
     1141 ttataagaac aacgttgaag attaaaaaag tgtttcaatg ctaaaattgc aaaatacttc
     1201 aatgttatga gacaaactgt ctataagaat caatttccac ccatttcatc acttgttaaa
     1261 agtttatgat ccttttgatt tttatattaa tttatctgta tttaatacag attttattta
     1321 ttagttcatc tgcctattgt attttatttt gttgccttac catctgaagt aaatatactc
     1381 ttaattgtca aattaagtta gacagatcat caatacttac gtaactcaaa aatacttcca
     1441 aaggtgttcg ataatccagt gattttctag gaagattatt tctgcgccag cattttctaa
     1501 tgtttgaatt tgtgttttgt aatcttggtt gcttgtgcta attcttgaat agccgtaaat
     1561 tgccaaaatt tcatcaccct ttctggacat aagtttctga caccagttaa aatcaagtct
     1621 atcagtaacc catacacccg tgaggacggg tgtattttta atccccctag aaggggtcga
     1681 cactcgctgc cccttaaaag gggattttta aaagaccgcc aactgctcat cttcactcac
     1741 ttacttctct ttatttttta aatggttcta cgtactctct tttacttata atatatcgaa
     1801 tgcgatcatc agcttcttgt tcacggatgt atttttcatt tgtcttttga ttcaatccga
     1861 ctgtactcac atagtatctc ttcgaccaaa aggatttgtt tccgtattta tatttgagat
     1921 ttgcgtgctg ctcgtggatt agtaccgcac tacgaccttt cagatacccc ataaaactgg
     1981 atatacatat ttttggtggt actcgaacaa gcatgtgaat atgatctagc attgcatgtg
     2041 cttctatgat ttccacatct ttcatttcgc acaacttcct aagtattttt ccaagatctt
     2101 ttcgtaattg cccatagatt acttttcgtt gatattttgg tgtaaaaata atatgatact
     2161 tacaattcca acgagtatat gctaaacttt tatcgtcatt tgacatgaaa aaactccttt
     2221 cgatctgatg agcggttggt agccactcac tagtatatcg aaaggagttt ttatcgctaa
     2281 agatacttct tccacgcgta gaaacgcgcg gttttcttgt ttcgcacgct ttacgcacaa
     2341 aactgactga agtcattaag aaaataaaag ggtctaaaac ttttaagttt tgtaccgacc
     2401 cccaaaagtt agaccaaaaa atctaacttt tggaggtcgg tattttttat ggctaagtat
     2461 acttttgaac ttaaattaaa gatcgttcat gattacttgg atggtaaagg cggaagtgat
     2521 tatctggcaa agaaatattc cattaaggct ccatcacaag tgaagcgctg gatcaatgcc
     2581 tatcaagaat ttggtgaaga gggtctagta agaaagcgac aaaagaaaaa atattctgtt
     2641 caatttaagc tggatgcgat agagttatat ctaacaagtg agctgtccta tcgtgaagtt
     2701 gccaacacac ttaacatgaa caaccctaat ttgatcgcta gttggatgcg tcaattccgt
     2761 gagggtggga tcgatggact ctcaaaaacg aaaggatgtc cacctatctt gtctaagaaa
     2821 aatgaaccca aaaataagaa aaaatctaca actaaagcaa cgtctaaaga acgtgaacgc
     2881 atcgaggagt tggagaaacg agtccgttcc cttcaaattg aaaatgcctt tttaaaagaa
     2941 ttgaggaagc tgcgaaaaca ggaagcccaa caacgacgaa tgaagcaatc gcacgaatca
     3001 tcgcaagcct ccgaggaccg tttaaattag ttgagcttct agaaacttta aagttcccta
     3061 aggcaatctt tatgtactgg caaaaacgat tggaccgtaa aaatccagat caagagattg
     3121 aagcggaaat gcttaaagtt cgggagaagc acaaggatta tggctgttta cggatgacca
     3181 atgaactaag aaaccgcggt ttctctatca ataaaaagaa agttcagcgc ctgatcaaga
     3241 agctaggaat aaaagtaacg acatacacac gtaaatcacg gcgctacaat tcttatcgag
     3301 gacaagt
//
LOCUS       DAFLWC010000162         3186 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.168, whole genome shotgun sequence.
ACCESSION   DAFLWC010000162 DAFLWC010000000
VERSION     DAFLWC010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3186
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.168"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            582..914
                     /locus_tag="L1V17_002880"
     CDS             582..914
                     /locus_tag="L1V17_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HBN1237573.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            1533..1874
                     /locus_tag="L1V17_002881"
     CDS             1533..1874
                     /locus_tag="L1V17_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HBN1237574.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
     gene            complement(2111..>3186)
                     /locus_tag="L1V17_002882"
     CDS             complement(2111..>3186)
                     /locus_tag="L1V17_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBN1237575.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT         1023 a          477 c          658 g         1028 t
ORIGIN      
        1 taatacgcga agagagataa tttcattatt taaacaagct aaaaatcttg atattacttc
       61 ttttcaggca atacgaatat tattcgctta cattttttgt ataaatttaa ttgtctgcta
      121 tgcttgtgat gaattgattt tcgttttgca cttttggatg ataaatttgg acaattgaaa
      181 atacaaaaaa aagaaaggcg gtatgaactc ggaaggctgg taaccttcgt cagcgttcat
      241 acacggcatt aagatttggc ccttaatgcg ttaacctttc agtgttacgg tattacccgc
      301 aatggattta gtataacaga tattcaaaag tgataccact ttttttggct gtgttaaggt
      361 taaaaatacg tgatattacg atgaatctat gcctaagcat aatgttataa aaatgtccgt
      421 gtggctcttt gccgtatgac gaacgctgaa attagaggga acgcatgttt ggatgcgttc
      481 cctctttttt gtttgtcatg aacgaaaatc aattctctat ttttgaaaaa taacaagaaa
      541 aacttgttaa aaatatttaa agaaattggg tggtttattt tatgtcatat acaggaattt
      601 tgagtctcaa agatatttgt cactacggta aacggtgtac cgctacagag aaaatcacga
      661 agaaactatc aactggccaa agtaaaaccg ttgtgcagtg taagaaatat ataatccaga
      721 aagacaaagt ctcagaggaa atgatttatt acattgggaa acaaaagcaa ataattttaa
      781 aagatcctat ccccttaaaa gagctatatc caacaatcaa acatgtttat gaccaaaacg
      841 gtgtactgat tggtcgaaga aaaaatggag tcttgcgttg taccgcaaaa gggatggggc
      901 gtttgatcgg ctgaattgat cattctcata acttgtattt tatcgttttt cgcttgcttg
      961 aaaatattgt cgagacttct aaaggaactt agagtcacta gaaaaataag gagtagactt
     1021 gatctatcaa caattccctt cggggagtga cggggtaggt tttaacgatt ggtaacgtaa
     1081 aaaattggtc aatcgagtaa atgcgcttgt ttggatagtg gtgaaatgaa tttgtgtaaa
     1141 taataagcgc agagtaaaca agagggaatt tagaagttag acaagttaga atagcgtcta
     1201 gattaatcat gagcagctac taagggatct agactttgac gcaaactcat ggaataagga
     1261 gtaggtcttc tcgtaatggg gaggacgcac aagaaattgt gtcgtgtgct gcagtacatg
     1321 tagatacttg cgaggacgtt gattattgga tcaatcgagc atttaccgct gtctactagg
     1381 gtttctcgtt tcggacgcca taaacgagtc gaaatttttt atgtattttt aagtaaacga
     1441 aaaacgataa aatatgaaca agtcctgaat aaagtgaaaa aattgatata aaacatagag
     1501 aaaatgaaat ttacgtaatg gaggaatgac aaatgaaaaa ttatgatccg aatatacgat
     1561 tgggcacaca tactattaag gtttctttcc aacgttggga ttacaaagga tttgtgacgt
     1621 ttagaagggg cggaaattgt aaaggattag atgttttagc attagacgag gatgatttat
     1681 acgatcaaac attgactgat aatccaattg gattcggctt gctacctgaa gatgatgaag
     1741 gtaatgaatg gtttaaaatg acgcttatga atgataatgg agacgaatta tctgttgaag
     1801 atacttggtc atatttgagt gattatattg tcagctttga aatcattgaa tttgtagcgg
     1861 ataaagaaga ataaaaactg gaggaataaa ttttacagat aaaggcttag aaggagtcac
     1921 gacgattaat aaaaaggtag tattacctta ggcattgagt aaggaattta tttagtctaa
     1981 tggtgataag tcaagatgaa atttaagatt ttctttattg agtaatatgt tttgaagcgc
     2041 acgaaactag acccgatcaa aatcaaattt ttttcgggtt gattcaagga tttgcgtcaa
     2101 taacggattg ttatttctct atcacactcc ttggtggcgt atagagttgg tgtttacgta
     2161 gtagcgtatc caccagacgc gtaaattttc ttgcggttag gacgagtgca cgtttgtgtt
     2221 gatgctttgg aacctcctta tatttacttt gataaaaagc tttgtattca ggaagataat
     2281 tttttacaga gttggcagct tcaactaagt agtatctaaa atatcgattt ccttgttttg
     2341 tcagaggtgt attttgcgac tgatagtttc cagattggtt cactttccaa cttaatccag
     2401 cgtattttgc caattttgtc tgatcttcaa atctttcgat ttgaccaatt tcagcgatta
     2461 aaccggcagc atagacttta ccaacgcctg gaatactggt taagcattga tattctggaa
     2521 tgacaacaat tacttgttcg atggctttat ctaattcttt gatatttttt tcaagtgctc
     2581 gtatttctcg tacgagaaca cttaaaacaa cattaattga ttcttgtgca agagcaccta
     2641 ggcggtaact catggtaatt gcacgttgaa ttgctttagc gattttttct ggttgcttga
     2701 aacggccttt tcctttttct tgaagtaaat cacagaaagc ttctaaagga agctcagcaa
     2761 gttcatccaa tgtgaaatct tccgtcatga gtgaaatgag ggttgcacta aaaagactcg
     2821 tcgattcgtc tcgcatttct cgagcaagcg tattacattt gtacgttaga ttttcaagaa
     2881 aatgttgctt tgtacgaatc aattgcttaa taagttgata gcgagtacgt gttaaacgct
     2941 gtaaggccat gtatttctct tctttgatag gggaagttgt gaatcgttga atacgcaaga
     3001 aatcagcgat tcttaatgca tcgtttcgat cagttttatt ctcatcaaac atgcgactaa
     3061 attgtttcac ccgaaaagga ttttcaatcg ttacaagtgt gttgagcttc tttagtttct
     3121 catcttcatg aaaaaacatg gaaggatgga agctgtacat ggacgttgac tccatgccaa
     3181 tcacaa
//
LOCUS       DAFLWC010000163         3088 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.169, whole genome shotgun sequence.
ACCESSION   DAFLWC010000163 DAFLWC010000000
VERSION     DAFLWC010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3088
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.169"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..712
                     /locus_tag="L1V17_002883"
     CDS             <1..712
                     /locus_tag="L1V17_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBN1237576.1"
                     /translation="ANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTL
                     DTPYNQPGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSDD
                     KPVIDPTRAGAANPTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNT
                     GKELARVKADGIYRPDVNQAYNTLGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTK
                     GGAQDFHDKRWYLNIPQR"
     gene            969..1616
                     /locus_tag="L1V17_002884"
     CDS             969..1616
                     /locus_tag="L1V17_002884"
                     /inference="COORDINATES: protein motif:HMM:NF014505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBN1237577.1"
                     /translation="MPNKNYRVYKRGTIVYVDFGVNVGYELSGNHFAIVLNNKDNSKN
                     GVVCVVPISSKKKSNYVSVGKILEVASIKQFISQADKLKEKLRIIILLSLNRGIIDES
                     DLNSFIKDIEAKGEKLSVEEVEKRAVKHNLVCETREQVIKEIKSLSEDMVKYQKVFNC
                     YKKYTQESYVMPLNIQTISKNRIRRINKFDPSGNMKAPGNVLNEVDESLKKYFTK"
     gene            1899..1972
                     /locus_tag="L1V17_002885"
     tRNA            1899..1972
                     /locus_tag="L1V17_002885"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1933..1935,aa:Ile,seq:cat)
     gene            2518..>3088
                     /locus_tag="L1V17_002886"
     CDS             2518..>3088
                     /locus_tag="L1V17_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HBN1237578.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNG"
BASE COUNT         1100 a          470 c          576 g          942 t
ORIGIN      
        1 tgctaatgca aatagtcctg tgcagattga gttacaacac acacatgata aagcaacgtt
       61 tgagaaaaac tacaaggcat acgttgaatt agctagagat tcagcaatga aatatggtat
      121 tccacttaca ctagacacac cgtataatca accagggatc aaatcgcatt tatgggtaac
      181 acaaaatatt tggggcgatc atacagatcc ttacggttat ctttctgaaa tgggcgtaag
      241 taaagaaaaa ttagcctatg atttggctca tggatttacc gatgaaaatc cgacaacttc
      301 agatgataaa ccagtcattg atccaactcg agcaggtgct gcaaatccta ccctgacaga
      361 tggaacaaat tacgcccaca ttgatcagtt cggagaaatc gaaaacgcaa acttacatgt
      421 ggctggttgg cacatcgcta actataaata cgagtatatc ttcattatgg attacaatac
      481 tgggaaagaa ttagctcgag taaaagctga tggaatatat agaccagatg taaatcaagc
      541 ttataatact ttaggaaatg ttggctatca tgtatctttt aacatgcgca acttccctaa
      601 taagaaagtc tatgtaatga tgcgggcaac gaatgatcca gaagggaaca ctaaaggcgg
      661 agcacaagat tttcatgata aacgctggta tttaaatatt ccgcaacgat aaaaatagcc
      721 cctcgttttt gaggggaagt acataatgca aatttgtcca taacttattg attatcttgt
      781 aaaaatgcgg taatttaata gttagtgaga agaggtgctt aattatagtt aaaaaagagg
      841 aaatagaagc agcatgtaac caagcaaatg ttaggtttat tggagaagct ttatctggat
      901 atcctaagta taaatactta cacaactggt tacaaagtaa aagtttttat cttaataaag
      961 aaagatgcat gcctaataaa aattataggg tttataaaag aggaactatt gtatatgttg
     1021 attttggggt gaacgtgggt tatgagttat ctggtaatca ttttgctatt gttttaaata
     1081 ataaagataa ttcgaaaaat ggtgttgtat gtgtagtacc aatctcttca aaaaagaaaa
     1141 gtaattatgt atctgtagga aaaatattag aagttgctag tattaaacaa tttataagcc
     1201 aagctgataa attaaaagag aaacttagga taattatttt actttcatta aatagaggca
     1261 tcattgatga aagcgatttg aatagtttta ttaaagatat tgaagctaaa ggtgaaaagc
     1321 tttcagtgga agaagtagaa aaacgagctg taaaacataa tttggtttgc gagacaaggg
     1381 aacaagtaat taaagaaata aaatcattat ctgaagatat ggtaaaatat cagaaggtgt
     1441 ttaattgcta caagaaatat acacaagaat cctatgtaat gccacttaat atccaaacga
     1501 ttagtaaaaa tagaattaga agaattaaca agtttgatcc ttctggaaat atgaaggcac
     1561 ctggaaatgt cctcaatgaa gtagatgaaa gtttaaaaaa atattttaca aagtaaacga
     1621 tatttttgtt gacatttttc tgttcgttag ttaccatgta gttatagaag gacgtaagcg
     1681 cctattttta atgtacacat cgggacgtat gcgcccacat agaaacatag ttgagagaca
     1741 tctatatggt gtctcttttt ttattaatat gcaaaaaagt ctagtttttt caataatatt
     1801 tatgtaataa taaattagcc accacaacaa agaatgaaac ccattattat ctagtctatg
     1861 tccattcttt ttgtttgcag tagttgtgat ggctttccgt actcttagct cagttggtta
     1921 gagcagacgg ctcataaccg tccggtcgta ggctcgagtc ctacagggta catactctaa
     1981 gtgatttaaa ttgcgaataa aatataaaaa tgactcccct tttgactccc ccaagcagta
     2041 tatggatgtc tctaaaagtt gtttttttag ataataaaaa gctgataata agcgaaaaac
     2101 acttaaaatc agctttaaac cctattctcg aaatccggcg aaccggctaa taccggcgcg
     2161 caggttcaaa tcctgtacct tccttatatc aacgattaga ggttgtgaag aagctgtcct
     2221 gcatcaagta ataagaacgg ccaaacaaaa atagcttttc ctattttttc gtttgattgg
     2281 gcttattacc gcagatgcaa gcttttgaac accgtttgtt cggaataagg ggctgtgaca
     2341 agacttttgt cacagcccct tattgttgta cttttaacct acaatatttt ttgattcccc
     2401 ctgagtacta ttttttataa atgctagtaa atcaatcttc tttggccttt ttttgataaa
     2461 aaaaatacta gatgtaagat aaaagtgtaa aaacgatttg ttttaggagg ggaaacgatg
     2521 tgtaccgcaa tcacttatgc aacgaaagac cattattttg gaaggaattt tgattatgag
     2581 atgtcttata atgaagtggt cactattact ccaagaaatt atcgtttcga ttttagaaag
     2641 gtaaaaaatt tagataaaca ttatgcaatg ataggaatag cagctggggt atccaactat
     2701 ccactctatt atgaggctac aaatgaaaaa gggttgagta tggcaggact gaattttcct
     2761 ggcaatgctg attataaaga attacaagaa ggaaaagata acgttgcacc atttgagttt
     2821 attccatgga tactagggca atgctcaacc atagacgaag ctaaagaatt attggctact
     2881 atcaatctag tcaatatcga ttttagtgaa aaactaccct tgtcaccttt acactggtta
     2941 ttagctgata aagaaaaatc gatagtaatt gaaagtatga aagatggact tcatttatat
     3001 gataatcctg tcggtgtgtt gacaaataat ccgccatttg attatcaatt atttaatctg
     3061 aacaattatc gctcgctatc aaatggaa
//
LOCUS       DAFLWC010000164         3003 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.170, whole genome shotgun sequence.
ACCESSION   DAFLWC010000164 DAFLWC010000000
VERSION     DAFLWC010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.170"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..1131)
                     /locus_tag="L1V17_002887"
     CDS             complement(<1..1131)
                     /locus_tag="L1V17_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBN1237579.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIEGKVLSMYARGMSQCDIAATVEDIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKVRGVEDVFFISMDGVSGLKEGAKAIFPSVIVQRCIVHLVRNALRYLPSK
                     DYKEVCRDMKKFYSASSLNAAHAAFDSFQNRWSHYSGAVDVCKRNFSHVEQLFDYGSA
                     IRKIMYTTNAVESIHSSFRKVTKKGVFSNENAQTVDKVHFMDD"
     gene            complement(1261..2637)
                     /locus_tag="L1V17_002888"
     CDS             complement(1261..2637)
                     /locus_tag="L1V17_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1237580.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(2637..>3003)
                     /locus_tag="L1V17_002889"
     CDS             complement(2637..>3003)
                     /locus_tag="L1V17_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1237581.1"
                     /translation="IENIRLVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIA
                     RALVSDAPIILADEPTGNLDSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADII
                     LELSGKKLKKVNKMNLEVE"
BASE COUNT          913 a          575 c          418 g         1097 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgcgcattc tcattagaga acactccctt
       61 ttttgtgact tttctgaagc tagagtgaat actttcaact gcattagtag tgtacatgat
      121 ttttctaatg gcgctgccat aatcaaagag ttgttcaaca tgagaaaagt ttcgtttgca
      181 tacatctact gcaccagaat aatgagacca ccgattttga aaactgtcga aggcagcgtg
      241 tgcagcgttt aaagaagaag cactgtagaa ttttttcatg tctcgacaga cttccttata
      301 atccttactt gggaggtatc gtaacgcatt tcgaacaaga tgaacaatac agcgctgcac
      361 aatgacagaa ggaaaaattg cttttgcgcc ttctttgaga ccggaaacac cgtccatcga
      421 aatgaaaaaa acatcttcta caccacgtac tttcagttca tcaaatactt gcatccagcg
      481 atttttagat tctgtttgat tgagccatag gcctaaaatc tccttgtttc ctttaagatc
      541 atagccaaga atggtgtaca cagcatattc tttagcttca tagttttcgc gtaaagtgac
      601 gtacatacaa tcaacgaata gaaatgcata acacttggct aatggccgag cttgccattc
      661 ttccaattca ggaaggacgg catccgtgat atcagaaatc atttcgtggg aaatatcaaa
      721 gccgtaaata tcttcaacgg ttgcggcgat atcgcattga ctcattcctc gtgcatacat
      781 ggaaagaacc ttaccttcga tgtcggagac atctcgtttt ctattaggaa tcaactcagg
      841 ttcaaaagaa gcctcccggt ctctgggaac atcaatgttt actttaccaa agctcgtttt
      901 aagcgtctta ttgccataac cgtttcgtcg attgtcatgt ttctttggct ctttagaatg
      961 ggcgtcatac cctaaatggt tattcaattc tccttgaagc attttttcaa ataagggacc
     1021 aaacacatct tttaaaacat cttgcatatc ctctacagat tcgggttgat aagtattcaa
     1081 aatggattca gctaacttct cagcatcagg atttcttttc tttctagcca tcgtgtaatc
     1141 acctcttgat cttattttag aaaaataaaa accgtgaagc aaccacccgc ctaggattga
     1201 tggttactta cacggtttat attacactct catttttggt gctaaaaagc accgaaaatt
     1261 ttaattattg tcaattaata attcttttgg attccttctt aatatattga atgaagaaat
     1321 aatcaatgat acaagaagta ctaaactcat aaatataact acataaatca tgaatttagg
     1381 taatacattg atatctaaac ttgataatgt cttgttaaat ccttcagctt ctgccccacc
     1441 acctaattgg ctagatgcag attgtttagc tatttgttta gctatatcac cagtaacctt
     1501 attcaatata ttattcccaa gcttgtcagc tgtatattga gctaagaaat aggaaccaac
     1561 gaatgcgggg attgatataa ataccatctc aattaggaat tgaccaaaaa tttctaattt
     1621 tgatatacct aatgatagta atactgctat ttctttcttt ctagcattca tccataagaa
     1681 taataataat gaaactacaa ctcctgcaaa tattaatgag ccaaaaaata atttatttga
     1741 aattgagtaa atacctgata tagattgttg taatgcaggg taatttgatg aacttttaat
     1801 caaattatat tctctccaat ttatatctaa tttcccaaga tcttttatta cactatcaag
     1861 attcttatca ccttttacaa agaatgttgc atcttggtat acagctgtat cttcggtatt
     1921 accataaact ttagcagctg tatgaatatc agtgattaat gtattttcgt atagttcttg
     1981 tgctgcactt actccaccgc tattatgccc atcgaataga cctttaattt ctacttctac
     2041 tgtttcatct gcacctttct cattatcagc atcaaataaa ttagatttta tttttatctt
     2101 atctccaact ttaaggttat ttttttcagc taaatcttta tgcattaaga ttttattttt
     2161 atcttcattt tctaaatgct ttccttctac taatttatat gcttctgata caaattttgt
     2221 ttcttttgtt gagtcgttaa ccccagttaa cataactgtt cttttaaaat tctttgctct
     2281 ttcaggtgat tgattcgcaa gagtctcttg agtttcaata atatcataat caactaaatc
     2341 tgcaacactg tttattcttt ttacatagga gtctatacta tctgtttgag atatcttttt
     2401 aatatcttca ccttttacat ttcccccacc tctaggtgtt cctggattta cttgtctatt
     2461 tatctccata gaaaaactat ttgttatatt agcaaatgtt tcttttgaag ctctgtccgt
     2521 agcatcttta atagataaac taatgagact taaagttgac atagataaaa taactaatat
     2581 gataattaat gattttaaac tttttctagt tacataagca aatgcatttt ttatcattat
     2641 tcaacctcca aattcatttt atttactttt ttcaactttt taccacttag ttctaaaatg
     2701 atatccgcag aatctgctac ttccttacta tgtgttacaa ctattacaca tttatttcta
     2761 tctttagcta atgtctttaa tatattaatt atttctccag cagtaacact gtctagatta
     2821 ccagtaggct catcagctag tattattgga gcatctgata ccaatgctct agcaatagct
     2881 actctttgtt gctgtccacc agataatttc ataacatttc tttttatttg ttttttatct
     2941 aaacctagtt caaacaagat actttcatct gctgatttat ttactaatct aatattttca
     3001 att
//
LOCUS       DAFLWC010000165         2917 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.171, whole genome shotgun sequence.
ACCESSION   DAFLWC010000165 DAFLWC010000000
VERSION     DAFLWC010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2917
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.171"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            36..1514
                     /locus_tag="L1V17_002890"
     CDS             36..1514
                     /locus_tag="L1V17_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HBN1237582.1"
                     /translation="MKKLSQKRLAQIIIDSRKSLKMTQQQLAVATGINRALISRLESL
                     DFIPSIQQLESLAEVLNFEPTDLFINESNKSNRTKHQSKNIAVAGTGYVGLSIATLLA
                     QHNQVTAVDILPEKVKQINNKKSPIQDDYIEKYLAEKNLNLIATTDGAAAYREADFVV
                     IAAPTNYDSKQNYFDTSAVESVIKLVLEVNPKAIMVIKSTVPVGYTESIRKKYNTKNI
                     LFSPEFLRESKALYDNLYPSRIIVGTDQTDKTLREASHTFADLLQEGAIKKDIETLFM
                     GFTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLNTQEIIHGVCLDPRIGTHYNNPS
                     FGYGGYCLPKDTKQLLTNYNDVPQNMISAIVDSNRTRKDFIADRVLELAGTYEANSSW
                     NAEKEKEVVIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGATIVIYEPTLENNTTFFG
                     SKVINNLDDFKNISHSIIANRYDSNLDDVKEKVYTRDLFQRD"
     gene            complement(1582..2673)
                     /locus_tag="L1V17_002891"
     CDS             complement(1582..2673)
                     /locus_tag="L1V17_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HBN1237583.1"
                     /translation="MLELNTSLSNRTILITGAAGFIGSNLVLELLRTQSSIKIIGIDN
                     MNDYYDVSIKNYRLSEIETEAKNHPGSTWNFIKGSIADKATIDFIFDNYKPSIVVNLA
                     AQAGVRYSITNPDMYIESNIIGFYNILEACRHSYDNGESGVEHLVYASSSSVYGTNKK
                     IPYSTEDKVDNQVSLYAATKKSNESMAHAYSKLYNIPSTGLRFFTVYGPAGRPDMAYF
                     GFTDKLRAGDNIQIFNYGNCKRDFTYIDDIVEGVKRVMQCAPEKIDGEDGLPIPPYHI
                     YNIGNNTPENLLDFVDILQQELIAAGVLPEDYDFESHTELVPMQPGDVPVTYADTSAL
                     ERDFEFKPSTSLRDGLRKFAQWYKSFYEV"
BASE COUNT         1024 a          521 c          459 g          913 t
ORIGIN      
        1 tttgttatta ttagcaacaa aaaaaggagt gcatcatgaa aaagttatct caaaaacgtt
       61 tagctcaaat cattattgat tctagaaaat ctctgaaaat gacacaacaa caacttgcag
      121 tagctactgg tatcaaccgt gccttaatta gtcgattaga atctctcgat tttatcccgt
      181 caatacaaca attagaatca ttagcagaag ttctaaattt tgaaccaaca gatctattta
      241 taaatgaatc aaataaatca aacagaacaa aacatcagtc gaagaatatt gctgtagccg
      301 gtactggtta cgtaggtctt tccattgcta ctcttcttgc ccagcacaat caggtaacag
      361 cagtagacat tcttcctgaa aaagtaaaac aaattaacaa taagaaatct ccaatacaag
      421 acgattacat tgaaaaatat ctagctgaaa aaaatcttaa tttaattgca acgactgatg
      481 gtgcagccgc ctatagagaa gccgattttg ttgtcattgc tgctccaaca aattatgata
      541 gtaaacaaaa ttattttgat acttctgctg tagagtcagt aatcaaattg gtgttagaag
      601 tcaatccaaa ggcaataatg gtcatcaagt cgacggtacc cgtaggctat accgaaagta
      661 ttcgtaaaaa atacaatact aaaaatattc tattcagccc agaatttctc agagaatcta
      721 aggcattata tgacaatcta tatccttcgc gaattattgt cggcacggac caaactgaca
      781 aaactttacg agaagcctct cacacttttg cagatttact ccaagaagga gcaatcaaaa
      841 aagatatcga aactcttttc atgggattca cagaagctga agcagttaaa ttattcgcta
      901 atacttacct tgcacttcga gtatcttact tcaatgagct ggatacttat gcagaaatga
      961 aaggactaaa tacacaagaa atcattcacg gggtttgctt agatccaaga attggcacac
     1021 attataataa tccatctttt ggatatggag gctattgttt accgaaagat acaaaacaac
     1081 ttctcactaa ctataacgat gttcctcaga atatgataag tgcaattgtc gatagtaatc
     1141 gtacaagaaa agactttata gcagatcgag tgttagaact tgctggcacg tatgaggcta
     1201 acagttcgtg gaatgcagaa aaagaaaaag aggtagtcat aggtgtatac cgtcttacaa
     1261 tgaagagtaa ttcagacaac ttccgtcagt catctattca aggagttatg aagcgaatta
     1321 aagcaaaggg ggcaactatt gtaatttatg aaccaacact tgaaaataac actacatttt
     1381 ttggttcaaa agtaataaat aatttagatg attttaaaaa tatcagtcac agtattattg
     1441 ctaatcgtta cgatagtaat cttgatgatg taaaagaaaa agtatatacc agagatttat
     1501 ttcaacgaga ttaaaaaata acacctcaga tttgtagtgt ctgaggtgtt tctataaact
     1561 tttataagta aaaaaataca attatacttc ataaaaagac ttataccact gcgcaaattt
     1621 acgaagcccg tcacgcaaac ttgtacttgg tttaaattca aaatctcgtt ctaacgcact
     1681 agtatctgca taagtaactg gcacatctcc tggttgcatt ggaactagtt cggtatgaga
     1741 ttcaaagtcg taatcttctg gtagcacccc tgctgcaatt agctcttgtt gtagaatatc
     1801 tacaaaatct agtaggtttt ccggcgtatt gttaccaata ttataaatat gatatggtgg
     1861 gattggtagc ccatcttccc catcaatttt ctctggagcg cactgcataa ccctctttac
     1921 tccttcaaca atatcatcta tataggtaaa gtcacgcttg caattcccat aattgaatat
     1981 ttggatatta tcaccagcac gaagtttatc agtaaaacca aaataagcca tatctggacg
     2041 cccagcagga ccatatactg taaagaaacg taaccctgta gacggaatat tgtaaagttt
     2101 agaatatgca tgtgccattg attcattact tttcttagtt gctgcataca acgatacttg
     2161 attgtctact ttatcctctg tagaataagg aattttctta ttagtaccat aaacggaaga
     2221 cgatgaggca tacactaaat gttccacacc agattctcca ttatcatatg aatgacgaca
     2281 agcttcaaga atattataga atcctattat gttagattcg atatacatat ctggattagt
     2341 aattgaataa cggactcctg cctgagctgc taaattcacc acgatacttg gtttataatt
     2401 atcaaagatg aaatcaattg ttgctttatc agcaatagaa cctttgataa aattccaagt
     2461 agatcctgga tggttctttg cctccgtttc tatctctgat aatctatagt tcttaataga
     2521 gacatcatag taatcattca tattgtcaat gccaatgatt tttattgatg actgagtacg
     2581 taataactca agaaccaaat ttgatccaat aaaaccggct gcgccagtta ttaatattgt
     2641 tctatttgat aaggacgtgt ttaattccag cattttttag cactcacttt ctttttttct
     2701 tatgaataca tatttgttat atattaaaaa atcttattta gacttatcta ttgtcacttt
     2761 tatcattcta atctttgcac gtagtagaat aattatacag ataggaaatt gctaagcaac
     2821 ccacttcttt ctattatcta ttaacttatt ctaaaacgaa tagaaattat tcttgatcac
     2881 ataagtaacc ttaaaagaaa aaatttaata tatgtgt
//
LOCUS       DAFLWC010000166         2897 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.172, whole genome shotgun sequence.
ACCESSION   DAFLWC010000166 DAFLWC010000000
VERSION     DAFLWC010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2897
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.172"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..1402
                     /locus_tag="L1V17_002892"
     CDS             <1..1402
                     /locus_tag="L1V17_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBN1237584.1"
                     /translation="EGEKVEVGGTVDLTDNVTNLPALPEGTTVTDVTPGGTIDTNTPG
                     NYEGVIEVTYPDGTKDTVKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNL
                     PALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKY
                     NPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDG
                     SSDEVEVDVTVTDTRSDADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKE
                     KVDVSTAGNKKGTVVVTYPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTE
                     PNAEVTVTLPDGSQHHGTADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVS
                     SNKKDSGKNGSKGSKTDNQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILL
                     GTLGLLGYKNRKKENE"
     gene            1536..2879
                     /locus_tag="L1V17_002893"
     CDS             1536..2879
                     /locus_tag="L1V17_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBN1237585.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
BASE COUNT         1138 a          395 c          566 g          798 t
ORIGIN      
        1 agaaggcgaa aaagtagaag ttgggggcac agtagatcta acagataatg ttactaactt
       61 gccagcgtta ccagaaggaa caacagtaac agatgttact cccggcggta caattgatac
      121 caacacacca ggtaattacg aaggtgtcat tgaagtaacg tatccagacg gtacgaaaga
      181 tacggtgaaa gttccagtag aagtgacaga caatcgttct gacgccgata aatatgaacc
      241 aacagtagaa ggcgaaaaag tagaaattgg aggcacagta gatttaacag ataatgttac
      301 taacttgcca gcgttaccag aaggaacaac agtaacagat gttactcccg gcggtacaat
      361 tgataccaac acaccaggca attatgaagg tgtcattgaa gtaacgtatc cagacggtac
      421 gaaagatacg gtgaaagttc cagtagaagt gacagacaat cgttctaatg cagataaata
      481 caatcctgaa ggacaaaaag tgactacaga cttaaataaa gagccagatg catctgaggg
      541 aattaagaac aaagaagatt taccaaaagg aactacttat gcttggaaag agaaagtaga
      601 tgttagcaca gctggaaata aaaaaggtac tattgtagtg acatatccag atggatcatc
      661 tgatgaagtt gaagtagacg ttacagtgac agatactcgt tccgatgcag ataaatataa
      721 tcctgaagga caaaaagtga ctacagactt aaataaagag ccagatgcat ctgagggaat
      781 taagaacaaa gaagatctac caaaaggaac tacttatact tggaaagaaa aagtagatgt
      841 tagtacagct ggaaacaaaa aaggtactgt agtagtaaca tatccagatg gatctaaaga
      901 agaagtagaa gttactattt ctgtagtaga taaaaaagca ccgaataaac ctcaagttga
      961 tcctattaca gagggtgacc aaattgttac tggtaaaact gaaccaaatg cagaggtgac
     1021 agttacatta ccagacggaa gtcaacacca tgggacagct gataaaaatg gtaattttac
     1081 agttaaagtt cctaaattag aggcagggac aaaagtgata gtaactgcaa ctgatgaatc
     1141 tggtaatact agtgaaccta ctaatgtagt tgtttcttcc aacaaaaaag acagtggaaa
     1201 aaacggtagt aaaggtagta agactgacaa tcaaggtagc aacagcaatc aagacaaaaa
     1261 tagaggcaaa agccagtcct caaaagtttt tcctaagacg ggagagagtg acagtaatat
     1321 ctttactatt agcggtggtt taatactgtt aggaacgtta ggattattag ggtataaaaa
     1381 tcgaaaaaaa gagaatgaat agaaaatcaa tttcttaagt cttctctgag aagaggaaga
     1441 atctttttct tcctcttttt gcttttttat gatgggaaat aagtgttagt taaagatgaa
     1501 tatacttttt atagaaagga aaagaatgta attaagtgga aaaaatagta attattggtt
     1561 caaaccattc agggctagcc gcagctcgat ttctaaactt aagcgattca aattatgaag
     1621 ttattctaat cgataaaaaa tcagaaatta gttacttgga atgtgggaca tcgttattta
     1681 taaaaggaga agtaagtaat ttagaagatc ttttttatca aaatagaatg acactaaatt
     1741 ctgagataaa aaagttattt ctagagacag aagttgacaa aattgatatt caaaataaaa
     1801 agattagttg tgtaaaaaaa gatggtacaa gattctctca agaatatgac aaagttatat
     1861 tagctacagg ttcaaagcaa attatgctag atataccggg gaataattta gctaatattt
     1921 tttcgataaa gaattttcca aatgcaaaag agatttttaa agctttggat gatagtacta
     1981 ttaaaaaagt aggaattatt ggagcaggat atattggagt tgaaattgct gaagccataa
     2041 gaaaaagagg gaaagaagta tatcttttcg atgttgcaga tagagtgttg tcgacttatt
     2101 acgaccgtag tttttcagat aaagttgaag aaatactatc aaaaaatgga atacatcttt
     2161 gtctatcaga aagtcctaaa aaatatttag gaagaaaaaa gattgaaaaa atagtcacta
     2221 caagtggtac ccaatactct atggatatgg tcgtacaagc tataggattt ctatctaata
     2281 gtccaattgg ggaaaaggaa ctcttgagag atgttagtgg agcatatcta actaatgaat
     2341 accagcaaac aaatataaaa gatatatatg ctattgggga ttgtgctaca acttttttta
     2401 cgtccattaa tagaagtagt gttgattttt ctatttctaa tgctctaaga acagcttata
     2461 ttgcaactca acatattaac aatcaagatt ttacaccttc tggttcccaa tttacaaatg
     2521 gcttttctat atttaattac aatttttacg cagcaggttt gaatttaaaa acagcacgat
     2581 tattaagtga gtctatagat tatatagaaa tagaagattt cattagacct gcttttttga
     2641 gaaaaaatag tcgtgtaaaa ttaagaatta gctttgaaaa aaatacaaag agaatagtag
     2701 gtgtacaact ttgtagtcaa gaagatttat ctggactatt atcaatgttt tctcttgcta
     2761 tagaagaaca aattacatta gacaaattga aaatgttaga ttatttattt catcctagtt
     2821 ttagccaacc ctataatttt attttaaagg cagtaacagg attaaacatt gaaacataat
     2881 cgttactaaa tgaaatc
//
LOCUS       DAFLWC010000167         2837 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.173, whole genome shotgun sequence.
ACCESSION   DAFLWC010000167 DAFLWC010000000
VERSION     DAFLWC010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2837
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.173"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            152..841
                     /locus_tag="L1V17_002894"
     CDS             152..841
                     /locus_tag="L1V17_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBN1237586.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            855..2357
                     /locus_tag="L1V17_002895"
     CDS             855..2357
                     /locus_tag="L1V17_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1237587.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            2370..>2837
                     /locus_tag="L1V17_002896"
     CDS             2370..>2837
                     /locus_tag="L1V17_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1237588.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKI"
BASE COUNT          914 a          392 c          558 g          973 t
ORIGIN      
        1 tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact cctaaatact
       61 ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag ttgttatcca
      121 aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt tagatcttat
      181 ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt acaaagagga
      241 agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag ttggtatacg
      301 tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac caatgattgg
      361 aattattaaa agagattatc caccagaatc tccattcatt actgccacta tgagagaagt
      421 agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc ttagaaatcg
      481 acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat atcctcatca
      541 gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata aagcaggaat
      601 agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac aagatgggcc
      661 agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg ctgagggaag
      721 gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag gtattgttgt
      781 gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag cattaagtta
      841 gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc atgttaccaa
      901 ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta acaaatgaga
      961 gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt ttaagtatta
     1021 tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca attggtattg
     1081 ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga gtagcttatc
     1141 tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa gatgcaacac
     1201 tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt ttacacaatc
     1261 gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca agatttattc
     1321 cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta atttggccac
     1381 caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt agtttaggaa
     1441 cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac cacaccattt
     1501 accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga tcaacaattg
     1561 ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact ggtctgttta
     1621 cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga ttaccagcag
     1681 catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat ggtgggcttt
     1741 attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt gaatatatgt
     1801 ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga ttatcttttt
     1861 attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt ttgatcgact
     1921 ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa ttaattcctt
     1981 ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc aaaaaattta
     2041 aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa gtaataaaca
     2101 aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt ggaaaagaaa
     2161 atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg aatggggaga
     2221 ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa gtgaagggtg
     2281 gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc aatcaaatat
     2341 taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag aaaaaacaag
     2401 aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta aatgatcctg
     2461 tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt tcaaaaattt
     2521 atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct attaatataa
     2581 aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt gaattacaag
     2641 gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa acctcgttgg
     2701 ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt atagttgttt
     2761 ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt gctcatggga
     2821 attcatgtgg aaaaatc
//
LOCUS       DAFLWC010000168         2769 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.174, whole genome shotgun sequence.
ACCESSION   DAFLWC010000168 DAFLWC010000000
VERSION     DAFLWC010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2769
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.174"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(76..1875)
                     /locus_tag="L1V17_002897"
     CDS             complement(76..1875)
                     /locus_tag="L1V17_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBN1237589.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(1999..2595)
                     /locus_tag="L1V17_002898"
     CDS             complement(1999..2595)
                     /locus_tag="L1V17_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBN1237590.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT          977 a          522 c          480 g          790 t
ORIGIN      
        1 aaaaacgcat atacctgcgg tggcaggtta tgcgtttttt gttgtataaa gacttttttc
       61 attaacgatt tttgattagc cgactcccaa aacaaaattt agcagtttat ctgaataagt
      121 gatttcttca tctgtttgtt tcacactttc atttagtagt cccatctcat cggttatgat
      181 accatccaca ccataaaaca tcatgcgact catagcatct gaatcgttga ttgtccatac
      241 atatacttct tttccgtctt ggtgggcaga attaatgaag ttacggttga tcgtactata
      301 ttccattgtc agaaaatcag caggcgtcac agggggccca acaatattga aaggtaagat
      361 gtagcccaca taaaagtttg gttctgcttc ttttaaatct gaaacggttt ggtacgtcaa
      421 actttgcaaa atatgatggt tctctaagat aactttgcgg tatttatgga caaatcgttc
      481 gacaaggtca tccgaatctt ttttagaggt cttgatctca ataagtaatt tttggtttag
      541 cttatgtgct ttttccaaat aagaatcaaa agaacaaaca ggggcttgca ctccgttttc
      601 agtaactgta agatttgtca attctttcaa tgtaagatcc tgtggtgttc catttacccc
      661 tgttaagtga cgaagatttg catcatgcat cactacgaaa tgaccatctt ttgtttcctg
      721 aacatccatc tctacataat caggatgata gtctctgctt gttttttcaa gtgcttctaa
      781 agtattttgc gccccatttt gggtactcac acctctgtga gagacagtca ctggttttgt
      841 ctgaacagct gaagtcagat aatccatatt gtaaagacag acgccaatac cgaaaaaaac
      901 tgcaaaaaga gtcaaaccag tgtttttcag cgcagagaaa cgcaagttgg gggcttgtgg
      961 gataaaccac ttagggatct caggcaagaa gccttcgtca tccatgaaat caacaatgat
     1021 ataaaaaatc cctacggtag acatcacgat attgaataat aaaatccctt gtaaaagcgt
     1081 catagcaaac acagcgctga tcaatgcata gtctgggaaa aattgttcaa ccatactttg
     1141 tgccaaaata acaacgatat atcctaaaga agaaaggagt aaaatcgtac cgccaatcac
     1201 aataaattgg cccgtgatgg ccaaaagacg cgatttggtc aatgaccagc tttcccgaat
     1261 ggctgctcga aaaggacgat ctcgtagaat catttccggt aaagcaaaaa tcagtcgaat
     1321 cccaatatag ccaaggaaaa tataaacgag taaaaaggaa ctgacgatga tccaacgatt
     1381 agcaaaaata aaatccataa tgaaagcggg gatttttatt tttgacagta gatcagaatt
     1441 aaaacttaat ccgctgatcg gtagaatcaa taaaaaataa gcaaggaaaa acaaaaaagt
     1501 aatgggtctc actttcttca gctgaagtat cgtcaagtgt aagagttgct tcaaagagat
     1561 tggttctttc tttttaataa aaaaaacact catcaaaaga aaagtaaatt cgaaataaac
     1621 taacagtaaa atcgtcatca aaactacgat taacgagagt agaaccccag gatgttgaga
     1681 aaaaattgaa ggaatattgt cataagacaa atagtcaatt gcccctcggt gtaaaataaa
     1741 acgggtcgta ctgctcaata agggtaaaca aataaataaa ataaagccat gcatcagcaa
     1801 gacatcacgg aaataagctt gtgttccttt taaaaagtcc caagcattac ctaagctacg
     1861 tttcaaataa ttcatcctat cacctgctct tcacattgta gcgcaaatct aatgaaaaag
     1921 gaaagggtgc agtgtgtttt gcagaccctt tcccagattt aacattgtca atcaatgact
     1981 aattttacaa aataaatatt atccaagaag accacttaga tattgacctc cataaatcaa
     2041 ggccatacta tataagaaaa tcgacagtgg tttagcaatc aaaatgatta gtgtatatcg
     2101 tttcactgac atgtttgtca atccagccat caaacataac gcatcgtcag gagcaactgg
     2161 aagaaaaata gctagagcaa acagcttctc aaaacggttt tgattatcca gccagccaat
     2221 atatttgtta tatgtcttat cgctaatcat ggaaagtatg aatggctttc cataacgacg
     2281 ccctagcaga aaaatgataa tcgaaccaat gcagattcca atatagttat agataaatcc
     2341 agcataaggg ccaaatatca ggacaccagc tgcagtactg atccctccag gaatgattgg
     2401 aataactact tgcaggattt ggatgaagac aaaaataatc ggtcctaaaa tgatggaatc
     2461 acctactaat cctcttaacg cattcaaatc tttgaaaaca cctaaattaa taaaataaat
     2521 cgtcagcgcg attgataggc ctaatccgat aatggatatg aaatttatca gttttcgaga
     2581 ggcagcaata ttcattattc atcaactcct tagaggttct ttgttaacta tactttacta
     2641 gaaaagcaac taactgcgcc attttttgat atgacagaaa acaaacaatt ttgtaagttc
     2701 atcataagta taaaagattg atctcaaaaa aacatccaac taaagactta tttaataact
     2761 tgttttttt
//
LOCUS       DAFLWC010000169         2677 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.176, whole genome shotgun sequence.
ACCESSION   DAFLWC010000169 DAFLWC010000000
VERSION     DAFLWC010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2677
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.176"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            692..787
                     /locus_tag="L1V17_002899"
     CDS             692..787
                     /locus_tag="L1V17_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBN1237591.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(1089..1334)
                     /locus_tag="L1V17_002900"
     CDS             complement(1089..1334)
                     /locus_tag="L1V17_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237592.1"
                     /translation="MRLEKEKMEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLEYKNM
                     TPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
     gene            1679..1963
                     /locus_tag="L1V17_002901"
     CDS             1679..1963
                     /locus_tag="L1V17_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237593.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            1966..2382
                     /locus_tag="L1V17_002902"
     CDS             1966..2382
                     /locus_tag="L1V17_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237594.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
BASE COUNT          882 a          498 c          430 g          867 t
ORIGIN      
        1 tccgtttttt catccattcc tttcttcccc ccttacaaat aaataataac ctttaacaac
       61 caactcgtaa ataggttggt tgttattata caaaaggata ttagtactca gataaaaagt
      121 tgttagtact cagataaaaa gttgttagta ctcagataaa aagttgttag tactcagata
      181 aaaagttgtt agtactcaga taaaaagttg ttagtaccct tctgtatccg ttgggagagt
      241 aaggctcaac tgccccctaa aaagggttct aaaaaatctt taaaaaataa ataaaataaa
      301 cgcgcgcgcg cgagcaaaat ttcccgccaa aaaatcaccc actttttaaa ataaacaggt
      361 tcgcgcatga tattaaactg ccaatctagc tccctatggt cgctgtaaga aggagtgatc
      421 gctacgctct cacattttac ttgcagcagt cgcctttagg ctccttcgcc aaaaataatt
      481 cattagggac tcctttgtgg cgtcctgaga gctcgtctaa gccgttctaa gacaagattc
      541 gataaaaact atgtccttcg ttctaaagcg ccttacaggc ggtcagggca agccctaaca
      601 accccaaggc aataaaaaac ttaggcttat ttttgctttt ttattgtata attgattgtc
      661 gcctatccga cagtcttgcg actggaagga ggtgtgtttc gtgttcacta actttatttg
      721 ctcccttctt gttgggcttt taagcgcttt gttcagttac tggttgaata accgaaacaa
      781 gaagtaaaac ttaattaagg cgactcagcc cacaaaaaaa gccccagaga atccgacctc
      841 tctggggctt tcgtgtgttt cgtgttcact tatttgcaat caaattataa cagaaataaa
      901 tatttatttc aaaaatatcc tacaaaagtc taaaatccgt aattatttct tatatgcaac
      961 atttacaaat aaagtcgctc tgagagctcg tatttttcga tttaagacgt tttatttagt
     1021 ttttggtgta tttcattggt ccaagctaaa aaactcttag aagcgatttt agagccattt
     1081 aaacccactt aattatattc tccatgaaat tcgctccatg cgtcaaaagc tgcgtctgaa
     1141 attccgccgt cttcgttcac tagttgcatt aatttttcca acgatcgttt tctttcgggt
     1201 gtcatatttt tatattccaa caatttttcg tctgttaaat cgaacttgat tgcttgaatt
     1261 gcttgctcta atttttctaa gttttgaaaa tattcgtaag gaaatttttc cattttttct
     1321 ttctccagtc tcacaatttt tctagaaata aaatcacttc tttgccgtct atactctcaa
     1381 aaaaaatgtc gtttgaaaaa ctaaataaat ttttgatcgt gcatttttaa atttggttat
     1441 cgattacacg tgcagcactc ccccccgaat tttaaagagc ataaggaaac gtgtacccac
     1501 tttctaaaaa aagtgggtag ataggctgtg cctatcacgt ttctcagaaa aaaatttgat
     1561 atcacttttt cgccatcgtg ggtagcttat gtatagcatt ttggcaaaaa acagctatac
     1621 aaatatagta tttgtatggt atacataaat tatacataat tgcaaaagga gattttttat
     1681 ggacatttta gttcggaata ttgatccaaa gtttgttgca acaatagaca aacgttgcca
     1741 agaactcacg aataaaacag gagaaaaatg gagtcgaaat aaatatctaa aagttttaat
     1801 cgaaagtgat tttgaccgtc aacttacgac ttacaaaaaa gaccaattcg atttattgct
     1861 cgataaattt attgctatcc aaacagaaaa tactcaaata ttaagcgagt atgtctacac
     1921 aaataatcaa atcattgaaa tgcttatcgg aggaatgata taaccatgag aaaaacttct
     1981 gtccaaaaac atgttacttt gtaccctagt catgttgacg ttttagattc catcatcgaa
     2041 aaaaatccag atatcaataa ctactcggaa gccattcgct ttttatgtat gagttatgaa
     2101 cccgatacca acacgaccac taccagcaat caggcaaaac taaatgctat gggaaaagaa
     2161 atttccatca tgactgaaat catcgcagaa tttgctgatt tatatctaaa agatacaggc
     2221 gttcttattg gcacaaattc taaagtatat caagaagtga aagaaaaaat cgaagctaaa
     2281 ctaaatccat caaatcgaaa tcgaccaaag aatcatcaaa aagaaaccag tcaaacagtc
     2341 acttctagaa atttcgaccc aacaaatttt ctaaaacgat aaaaaacaga taggagttat
     2401 tcctatctgt tttttattta gaagccccat acaatatgct agaatgtact agcaatctta
     2461 gtcggttgta agggacttgt ctacttgctt aatgtaaggg gggcgagttc ttttttattt
     2521 attcttctaa ccagttacgc agagaaatct ttggcaaatc tgacgttagg cttgaaaaag
     2581 taaattctaa tttggcgatt ttattgccct tttttgcttt tatttttgtg actttaagat
     2641 cattgaagta tttttttagt tctcgtaatg caggatt
//
LOCUS       DAFLWC010000170         2637 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.177, whole genome shotgun sequence.
ACCESSION   DAFLWC010000170 DAFLWC010000000
VERSION     DAFLWC010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2637
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.177"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            28..1035
                     /locus_tag="L1V17_002903"
     CDS             28..1035
                     /locus_tag="L1V17_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBN1237595.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            1047..2051
                     /gene="neuB"
                     /locus_tag="L1V17_002904"
     CDS             1047..2051
                     /gene="neuB"
                     /locus_tag="L1V17_002904"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HBN1237596.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            2048..>2637
                     /gene="neuC"
                     /locus_tag="L1V17_002905"
     CDS             2048..>2637
                     /gene="neuC"
                     /locus_tag="L1V17_002905"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HBN1237597.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHL"
BASE COUNT          971 a          338 c          523 g          805 t
ORIGIN      
        1 gactataatt cataggagga gatataagtg tttaaaggaa aaacaatatt agtaactggc
       61 ggaactggtt ccattggaag tgaaattgtt cgtcagcttt taaaatatga accaaaagct
      121 atcagaattt atagtagagg tgaagaaaaa caattttata tgcaacaaga gctctcaaat
      181 cacactaatt tgagattttt aattggtgat atcagagact ctcaaaggat tgattatgca
      241 tgtcgtgatg tggatattat ttttcatgct gccgcaatga aacacgttcc agcaagtgaa
      301 tataatccta tggaagctgt aaaaacaaat gtgatgggaa ctcaaaatgt aatagatgca
      361 gcgatcaaaa ataatgtaaa acattttgta ggtatcagta cagataaagt agtgagtcct
      421 actaacacca tgggtgcgac aaagttattg agtgaaaaat taataatagc tgccaatcag
      481 tataaaggaa aaacagaaac aatattttct tgtgtaaggt ttggaaatgt catggggtca
      541 agtggatctg ttattcctct ttttagtaaa caaataaaaa acaataaaga tattactttg
      601 acagatgttg atatgacacg atttatgatg tcaataccgg atgctgcaag attagttctg
      661 tctgctgcta tgaattcaaa atttggagaa acatatgtct taaaaatgcc ggcaatcaat
      721 attttaactt tagctcaatc attaataaaa atatataatg atacacatga tgaaaaatat
      781 agaggtgaaa taaaagttgt aggtatcagg ccaggagaaa aattatatga agagctaatg
      841 actacagacg aaattgaacg ctcatatgaa aatgataaaa tgtatatcat tccaccacac
      901 tatcatgcta ctgacgaact gtacaaagat tatgaaaaaa ttaaaatcac tgcatactct
      961 tcagatgcaa cagaattaat gagtggacag gaatttatta gaatcgcaaa agagaataat
     1021 gtcgtgactt ggtaaggagt tttatgatga aatcagaagt atatgtaatt gcagaaattg
     1081 gtgtaaacca taatggaagt ctagatttag ctttagaaag tattgataaa gctaaagaat
     1141 gtggagctaa cgcggttaaa tttcaaacat ttaaaacgaa taagctagtt tccaaaaagg
     1201 ctccaatggc aaaatatcag aaggataatc ttaaagagga cagttctcaa tttgaaatgc
     1261 taaaaaaatt agaattatct caatctgatt ttattagaat aaaagattat tgtatacaaa
     1321 ataaaattga ttttttgtct actccttttg atgaagaaag tgcagacttt ctaaaacaaa
     1381 ttggtgtaca aggatttaaa attggctcag gagatttaac aaatttacct tttcttagaa
     1441 aaatagatat gtatgggttg ccagttttat tatctacagg tatggctgat attcatgagg
     1501 tcagtgaggc tgtagattgt ttcatagata gtccagttac tattttacat tgtacttcaa
     1561 attatccggc tagttctgaa gatattaatt tattggcgat taacacatta aaagaaatgt
     1621 tcgggatacc cgttgggtac tccgatcatt cattgggata tgatgttggt atttgtgctg
     1681 ttgcgatggg tgctaaggta attgagaaac attttacctt ggataaggaa ctacctggtc
     1741 cagatcataa agcttcttta gatcctcagg aatttgcaga ttttgtaaag catattagaa
     1801 acactgaaat atttttaggt gatggtgtta agcgagcaat gccttctgaa cttagtacaa
     1861 aagaagtatc aagaaaaagc ctagtggtca ctgagaattt aaatgtggga gatattctta
     1921 cagagaaatc tcttacaata aaacgtcctg gaaatggaat agctcctaag tttttatatc
     1981 aatatattgg caaaaaagtt aaaagaccaa taagtgcaga tagtgttctg cttgaggaag
     2041 atgttgaatg aaaaaaatac ttatagtaag tggaacacga gctgattatg gaatatataa
     2101 acctgttgct gagaatttac tacaagataa ttgggatgta tcatttgttg tttctggaat
     2161 gcatttatcc cataaatatg gatttactaa agaattgatc ttagctgacg gatttagaat
     2221 tagtggagaa gttcaaagtt tgtttttaga gaacaataag ggaaacatgg ctcggtctgt
     2281 ggcattagag ataaatggtt tcacaaatat atttgaacaa actagccctg attttgtatt
     2341 attactaggg gatagaggag aaatgttggc agctgcgata gcttgtttgt atcttggaat
     2401 caaaacagca catattcacg gaggcgaagt gtctggtact gtagatgaat caataagaca
     2461 tgccataacg aaaatagcat ctgttcattt tgctgctacg gaaaaaagca aagagcgttt
     2521 aataaaaatg ggggaagatt cttggagagt ttttcccgtc ggagctccta gaatagatac
     2581 tattttaaat aatagattac ctagttttag agatataaaa gaaaaatatc atctaaa
//
LOCUS       DAFLWC010000171         2558 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.178, whole genome shotgun sequence.
ACCESSION   DAFLWC010000171 DAFLWC010000000
VERSION     DAFLWC010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2558
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.178"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(45..1022)
                     /locus_tag="L1V17_002906"
     CDS             complement(45..1022)
                     /locus_tag="L1V17_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBN1237598.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            complement(1025..2134)
                     /gene="pdhA"
                     /locus_tag="L1V17_002907"
     CDS             complement(1025..2134)
                     /gene="pdhA"
                     /locus_tag="L1V17_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HBN1237599.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
BASE COUNT          698 a          535 c          473 g          852 t
ORIGIN      
        1 aatttaaatt gataagccat gactttgttt cgtcccttct tttcttaaaa ttccgcgatt
       61 tcttttactt tgtcttcgat atcttttgca tttggcaacc agacattttc tgcttgtcca
      121 aatgggaaga ctgtatcagg tgcagaaact cgtccgattg gggcttctaa tgaaaggata
      181 gcgcgttctg agatctcaga aactacttgc gcggcaacgc ccgcttgtcg ttgtgcttct
      241 tggacaacaa ctacgcgacc agttttttcc acggattgaa tgatcgtttc tacatctaat
      301 ggcgcaactg tacgaagatc aatgatttca acagatatat tttcttttgc aagattgtct
      361 gctgctttga ttgcttcacg caccattgct ccgtatgtga taatagatac atctgttccc
      421 tcacgagtaa ctgctgcttt atccaaagga acttcgtaag cttcatccgg cacttcttct
      481 cggaatgagc gatatagttt catgtgttct aggaaaacaa ccggatcgtt acttctaata
      541 gaagaaatca atagtccttt tgcatcataa gggttggaag gaatcactac tcgaatacca
      601 ggagactgag cgatcaaacc ttctaaatta tccgaatgca attctggtgt atgaacaccg
      661 ccaccaaatg gcgaacgaat tgtgatgggt agatttctag tgccgctcat tcgatatctt
      721 gtacgagcca tttgagctac tacttcgtcc attgcttcga aaataaaacc aaagaattgg
      781 atttcaggaa ctggacgaaa tccttctaac gcaagaccga aactcaatcc tgcgattcca
      841 gattcagcta aaggagtatc gaatactcgg tcttctccga acttttcctg caatccttca
      901 gttgcccgga aaactcctcc gtttttccca acatcttcac caaaaacaac gacattctcg
      961 tcattttcta gttcaagtgc taaggcatct gtgattgctt ggatcattgt tttttgtgcc
     1021 atgattattt cgactccttc gcttcataaa ttgcaatttg ttctttgatt gattgtggag
     1081 atacttcgaa catgtttttc aagaaatctg aaaccttttg ttttggtact ttgtcggctt
     1141 cagcaatagc tgctttgatt tcttctttag ttgcttcgat gacttgttct tctttttctt
     1201 cagaccaaag tcctttttcc gtcaaatatt tacggaagcg gatcaatgga tcttttttct
     1261 gccaatcgtc atctgtgtct tttgtacggt agcgggttgg atcgtcacca gatagtgtat
     1321 gtggtccata acgataagtc agtgtttcga ttaggactgg tccatttcca ctgatcgccc
     1381 attcccgtgc cattttagat acagtatata ctgcaagcgg atccattcca tcgacttgaa
     1441 taccaggaat cccagctgcg acagcttttt gtgcaagtgt ttttgctgca gtttgttttt
     1501 cacgaggtgt agagatcgca tacccgttgt tttggatata aaatacggca tttgcatggt
     1561 aagcgccagc gaaattgatt gcttcgtaaa aatcaccttg tgatgaaccg ccatcaccag
     1621 tataagtgaa gacgacattt ttcttgtttc gtttcttcaa acctaatgca acaccggctg
     1681 cttgtacata ttgtgcaccg atgataattt gtggtggtag agctttcaat tcttccggat
     1741 aagaattacc tgcagcatgt cctcgagacc ataaaaaagc ttgagataaa ggtaaaccat
     1801 gttttactag ttgaggtaca tcccgataac ctggaagaag aacatcttct ttatcaaatg
     1861 cgtaagcact agccagctga cttgcctctt gtccagcagt tggtgcaaaa aagcctaggc
     1921 gtccttggcg gttcagcgct gttgaacgtt ggtctaatac acgagaccat accatatgag
     1981 tcattaattc aacgagttca tcatcggata aatcaggtac taaatctttg ttaactacgt
     2041 ttccatcttg atcaagtgct tgatatactg ggaaatctgc attgacttca tctagcagtg
     2101 cttggaagtc gatcggtgct tttttgtttg ccatttgtca cacattcctc tctcatctat
     2161 aagaaaatct cttcattctg cgattgaaac agtgaataaa actgtatcac tatttaaccg
     2221 tcttcattaa taaattatca tggatttatg agaaatacaa gctaaaagca caaattttca
     2281 cgatgaaagg aaattatgcc aatccgcata ttaacagcat tagtgaataa aatcacaata
     2341 aggaaagcgt tttatatttc atctgcattt tttctatttt ctaatcaaac ttacaaccat
     2401 ctgtttctat ttaaaaacgt tggtgttata cagttttgtt gcaaacattt attttattta
     2461 cacatcgtga acggacgtac aaataatggt tttttcttag tttctttata tcgtattctt
     2521 tttccgaaaa aaaagaaaca gcttgaaatt taaatcca
//
LOCUS       DAFLWC010000172         2555 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.179, whole genome shotgun sequence.
ACCESSION   DAFLWC010000172 DAFLWC010000000
VERSION     DAFLWC010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2555
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.179"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(56..1444)
                     /gene="ltrA"
                     /locus_tag="L1V17_002908"
     CDS             complement(56..1444)
                     /gene="ltrA"
                     /locus_tag="L1V17_002908"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBN1237600.1"
                     /translation="MRRPQKTRKLGYHQRASVEHEGYDEVRSTSCGEQRKQDGVENLF
                     GRILDRNNLNQAYLQVVRNKGAAGADGMTVDQLLPYLKEHREELLSNLRQGNYKPQPV
                     LRVEIPKPNGGVRKLGIPTVIDRMLQQAINQVLQPLFEPEFSDNSYGFRPNRSAHDAV
                     KKAKSYYEQGYRYVVDIDMKAYFDTVNHDKLMYFIERKVKDKQVLKLIRQYLMSGVME
                     NGLITTTEEGTPQGGNLSPLLSNIYLNEFDQVLENLGHKFVRYADDCNIYVRSKRAGQ
                     RVMKKSIQFLEEQLKLTVNREKSAVGSPLKRKFLGFCILPTKKGIKIRPHAKAKQRVK
                     SKLKQLTKRNRGRSIQLILKEIKQLMTGWINYYGIGEMKEFMRELNGWLKRRIRQYIW
                     KQWKNPRTKRKNLIRLGIDKAKAYEWSNTRKGIWSVSKSHILHRSLTDKELARQGYED
                     ISLKYQFVHSTY"
     gene            complement(2013..2390)
                     /locus_tag="L1V17_002909"
     CDS             complement(2013..2390)
                     /locus_tag="L1V17_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237601.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
BASE COUNT          632 a          567 c          464 g          892 t
ORIGIN      
        1 aactgacctt ccgcccctct cacaccaccg tacgtacgga cccgtatacg gcggttcaat
       61 aagttgagtg tacgaactgg tacttcaagg agatgtcctc atatccttgg cgggccagtt
      121 ctttgtctgt taatgatcga tgaagaatat gacttttgga gactgaccaa ataccttttc
      181 ttgtatttga ccattcatac gctttcgctt tatcgatccc taaacgaatc agattttttc
      241 ttttggttct tggattcttc cattgtttcc aaatatattg tctgattctt cgcttcaacc
      301 aaccgtttaa ctccctcatg aattctttca tctcaccaat tccatagtag ttgatccaac
      361 cagtcattag ttgcttgatt tcttttaaaa taagttggat acttcttcca cggtttcttt
      421 tagtgagttg tttgagcttg cttttcacac gctgttttgc ttttgcgtga gggcgaattt
      481 taataccttt ctttgttggc agaatgcaga atccaagaaa ctttcgtttc aatggacttc
      541 ctaccgcact cttttctcga tttaccgtca actttagttg ttcttcgaga aattgaatgg
      601 atttcttcat cacacgctgt cctgctcgtt tgcttctaac atagatattg cagtcatcgg
      661 cgtatcgaac aaatttatgt cctagatttt ctagcacttg atcaaattcg ttcaggtaga
      721 tgttacttaa caggggagag agattgcctc cttggggcgt tccttcttca gttgttgtga
      781 tgagtccatt ttccattaca ccactcatta agtattgacg gatcagtttt aggacttgtt
      841 tgtcctttac tttccgctca atgaaataca tcagcttatc gtgatttacg gtgtcaaagt
      901 aggctttcat atcaatgtcc accacatatc ggtaaccttg ttcataataa gattttgctt
      961 tcttcactgc gtcatgtgcg ctgcgatttg ggcgaaaccc ataactatta tctgagaatt
     1021 ctggttcaaa tagcggttgt aacacttgat tgattgcctg ttgaagcata cgatcaataa
     1081 ccgtgggaat tcctagtttt cttacaccgc cgtttggttt cggtatttct actcgcaaaa
     1141 caggctgagg tttatagttc ccttggcgta aattggatag taattcctcg cggtgctctt
     1201 tcaagtaagg aagcagttga tcgacggtca tcccatctgc accagccgcc cctttatttc
     1261 tgactacttg aagatacgct tgattgagat tattccgatc tagaattctc ccaaacagat
     1321 tttctacacc atcttgtttc ctctgttcac cgcaagaagt gctgcgcact tcatcatacc
     1381 cttcgtgttc cacactagct ctttgatgat agccaagttt tcttgttttc tgcggtcgtc
     1441 gcatcttctc acacctccta aattattcaa gattcttatt gttcagtcct tcgtaacggt
     1501 cagtgtcgtt actactatga cctcggctga cttctcatga ttcaccatca tgtcgccatg
     1561 atcgttgtgc tggtttgttt tcattcaacg cccacaacac cctcatgaga tctcccccgg
     1621 taagagtgaa aactttcctc ccatgtaact gctagattta ctgtataggt ttcgggcagt
     1681 attggacttt gtcttgtgat gaagacttat ccgacctaat tcagccttgt atctagtttc
     1741 tgttcgtcag ttcaggagtt tgcgtccgac ttccttcagc cacaacctca cgattgccgc
     1801 cttgtctttc gctaacagtt cctactgcca agcctgtagt ggactttcac caccaagttt
     1861 tcacccatgc agggcgcaca ccaaaaaaga agcagatccg ttagcggttc tgcttctttt
     1921 agtttattat attttcttat caataatagg aacctgattt taaaagcggc tacctcttta
     1981 ccgtgcctct ttacatacaa aaaatagagg aattaagcgt aaatggcttg gctattataa
     2041 ctaaaatgct ggttatggag atgttgcagc aagttttcga gaaaagcgta ttccatctct
     2101 tgtccattga ataagatctg gatacgataa tgatttttga aacgcttctg ttcatgaatc
     2161 tgactgattg aaagttcgcc tttgtgttct gtctgataaa gaaaagtcct tttacggcat
     2221 tcagcacagc gcttggttgc tcggcggatt tttcggaatg tataaaaact agtatcttta
     2281 ttgcataaat aaacgtcttt gatcgacagc aaatcattat atagacagga acgttcttca
     2341 gctgttaatt ctgataaaaa aagctgacct tgttttattg catcttccat cggcaagtgc
     2401 ctcctcgaac ccattatcca aatttttagt taattctaat ataccatcat taagtataaa
     2461 tgtaaacgct tgttgatggt ataagatttt cgtttctgat aaaacacgaa cattaaaaga
     2521 atctaatgcc ttaaatgtac atatttttgt tgatt
//
LOCUS       DAFLWC010000173         2463 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.180, whole genome shotgun sequence.
ACCESSION   DAFLWC010000173 DAFLWC010000000
VERSION     DAFLWC010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2463
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.180"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            160..2313
                     /locus_tag="L1V17_002910"
     CDS             160..2313
                     /locus_tag="L1V17_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBN1237602.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT          841 a          428 c          545 g          649 t
ORIGIN      
        1 atagttggat atgtaacttt aagtgattgc tgtgaaacaa aaagttgatt ttatcttgaa
       61 attaggtaaa gaatttcttg ctccgcccat tttttctttt ttattaagaa gtttttgggt
      121 acaatgaagc atgaatgtaa ataggcggaa ggataggaaa tgatgaaaga ttttatgaaa
      181 aaaatattaa atacttcttg gttagaaaaa ataagaaaag gtgcacaaga acctaagaac
      241 aaaacgtttc gccggtccca tgttcctttt cgcttaaatt ttcttttttt cattatattt
      301 acgttatttg ttgcgttgat tgctagattg ggttatttgc agatcgtgaa cggcgaagag
      361 atggaggcgc gagtgaagtc tacttctacg attacggtcc aagaaagtac tcctcgcgga
      421 atgatctacg actccacagg aaaagcttta gttacgaata aagcgaatca ggccatcaca
      481 tatacgagag gaacacaagt tacggctaaa gatttgcttg aaatcgcaac gaagctgaac
      541 tcgctgatcg atgttccggt agatgaaaat ctgacagata gagataaaaa agatttttgg
      601 ctggctgatc ccaaacattt gaaagaagcc acaaaaagac tttcggcaaa agaaaagcaa
      661 ttagggaaca gcgaacaata tagtgcgatg gtcaataaag tcacagctga tgagattaat
      721 ttaaacgagg agcaattaaa aattgctacc atctttaaac ggatgaatag tgcatatgaa
      781 ttaaacactg tctatatcaa aaactctggt gttactgatc aagagttagc tgttgtggca
      841 gaacgcgctt ctgaacttcc aggagtttcg actggcacag actggacacg agaatataat
      901 gcagcaagtt cactgaaaag tattcttggc agtgtgacga ctgaaaagca aggacttcca
      961 gcagatgaag cagagaaata cctagcaaaa ggttattctc ggaatgaccg tgtaggacaa
     1021 agttatttgg aaaaacaata tgaagatgtc ctgcaaggaa ccaaaaccca atatgaagtt
     1081 tcccttgata atgaaggaaa tgtttcgaat caaaaagaaa tcttctctgg ggaaaaaggt
     1141 tctaatttaa tgttatctat gaatgcagaa ttccaatcaa aagtagaaga aattttgaaa
     1201 aggaattatc aaacattgat caacaacggc aaagcacagt attcgcctgg tgcttatgca
     1261 gtggctatga atcctcagac aggagaagtg ctagcaatga ctggtttcag tcatgaacaa
     1321 ggttccaaag aaatcaccga gaatgcttta ggcacgatta ctagcgcctt tgatccaggg
     1381 tctgtagtca aggctggtac tttgacagca ggctgggcaa gtaacgcgat cagcggaaat
     1441 caagttttga ttgatgagcc gattcgtctg caaggtgctt cagaaaaaag ctctgtcttt
     1501 aatcgaagcg gacaagttgc tcttgatgca gtcaaagcat cggaattgtc ttctaatacg
     1561 tatatgatca aagtggcgtt aaagatgtta ggactagact atacacctgg aatgggacta
     1621 cctagtttag atgaagaagc taaagcttat cagcaattga gagactcttt caaagagttt
     1681 ggtcttggta caacgactgg gatcgatttg ccgaatgaat ctcctgggat ctcacgttct
     1741 gttgattata tgaagaagtt caatgcggat aatggcaaag aatggtatgc tccaggtaac
     1801 tttaccgatt tggcatttgg acagtttgac acatatacac caatccaatt agctcaatat
     1861 gcttcaacag tcgctaatgg cgggaaacga gtacagccgc acctagtcaa agcgatctat
     1921 ggcaatgacg aaaatggaaa cttgggtgaa gtgaagaaag aaattggcac aacagtagaa
     1981 aatacggtca atatttctgc agaaaatatg gcgatcctcc gtgaaggatt ccaccaagtt
     2041 gtccatggta ccgatcctta cacaacagcc aaaccattag ccagtgcgaa aatggacctt
     2101 tccgcaaaaa cagggactgc agaaacggtt gcggaaggtc atccagatat tgcgacagtc
     2161 aatagtaata tcgtggcata cggaccaaca gacaatccgg aaattgccat cagtgttgtc
     2221 ttgccgaact tattagacga acaagaccac ataaacttga cgattgctaa agaaataatg
     2281 gacgcgtatt atgatatgtt catggcaaaa taaaaaagag gtcgtgaaaa agccgcttag
     2341 tttcgagtat gaagaaaaat tttgtgaaaa tagcttctca catttttgct taaatttgac
     2401 ttcataccga gaaactggct tttgaacacc gtttactcgg caaaaaaggt tgtgacaaaa
     2461 att
//
LOCUS       DAFLWC010000174         2458 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.181, whole genome shotgun sequence.
ACCESSION   DAFLWC010000174 DAFLWC010000000
VERSION     DAFLWC010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2458
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.181"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(4..249)
                     /locus_tag="L1V17_002911"
     CDS             complement(4..249)
                     /locus_tag="L1V17_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237603.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(266..1117)
                     /locus_tag="L1V17_002912"
     CDS             complement(266..1117)
                     /locus_tag="L1V17_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBN1237604.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            1283..2287
                     /locus_tag="L1V17_002913"
     CDS             1283..2287
                     /locus_tag="L1V17_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBN1237605.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
BASE COUNT          790 a          420 c          495 g          753 t
ORIGIN      
        1 tttctatttt ttcggtatca aggcaaaaac aggtagttca ggtgaataaa tgacttcatg
       61 ttcgtgccag ggtttgacca ttagcgaatg atcgaaccgt tttttcagtt cttcgatgat
      121 ttgatcatgt gtccagtttc ttgcaggaaa atgttggatt ttctctgcat cgatcaaaaa
      181 gacaaaatcg gaatgaaaag tctgggtaac ttcttccgag agagaattca agcgttcgat
      241 tggatccata aaatcacctt tcgacttaaa attgggtagt atctgggtct tttgctttgc
      301 cgactacacc atctaactga tcgatttgtt tcatttcttc ttctgttaat tcaaaatcaa
      361 ataattcagt attttctttg attctgcttg gtgtcactga cttaggaaga ggaaggaatt
      421 cgtgttgcag cgaccaacgc aaagcaactt gtgcaatcgt cttgtcatgt gcttcagcga
      481 tttgtttcat ttcaggcaca tcgaagattt taccagtgcc taatggacta tatgcttcga
      541 ggatcatatc atgttttttt gcatactcaa ctacagttgt ctgtaattcg cctggtgcaa
      601 ggaaaacttg attgaccatc ggcataattt ttgctgtttt tgctagtgta tctagatggt
      661 ggggtaagaa attgctcaca ccgattgctt tgattttacc tgcttcatac agttcttcaa
      721 atgctcgcca tgtatctgca tttgcttgtt cccaattatc acgaaaagca acagggtttg
      781 gccagtggat caaaaacaga tctaaataat ctgtttggag cttcttcaat gattcttcaa
      841 aagaagacat cacaagttca tagctgtggt ttgcattcca taattttgtt gtcaagaata
      901 tctcttctct aggaattcca ctttccttaa tcgcttggcc gacgctttct tcattcttgt
      961 atccttgggc agtatcgata tggcgataac ctgcagccag cgcttcttta acagaggaaa
     1021 cagcgacatc cccatcaggt gtttgccatg tgccgaatcc tactaccggg atttcgtaac
     1081 catttgatag acgataagtg cttgttaatg aattcatact ttcagctcct tttttattcg
     1141 ttcaactata agtgtagcgc atttttcgaa aaaaagaatc cattttgttt ctactcttga
     1201 aatttttgtt taaaagaaaa tgattttgat tctggtattt ttgatttttt ttccgtaaac
     1261 taagacagaa gggaatgaga aaatggatat ctatttaaaa aaagcaattc tgcatattat
     1321 tgacagagaa actggttctc cagtcttttc acaaaaagag ctggatctga caaaagaata
     1381 tattcgtgat tttcttcaaa agaagatcca aaaaatctct tctgctcaaa caaaaactgg
     1441 acaactagca gaagaaagca tgatcgttga atcacttaaa atcgctcaag aaaattttgt
     1501 ggaagcaagt gaagcaatcg ttcagcggtg gttcgatatc taccaagaaa gtgaagaagc
     1561 acctagtgca gatgtatttg ttgtcttgta tgaattagat acagtgatgt acttatcttt
     1621 attgaaagtc aattatcgtg aggcttacac tcactttgtt gaagcagacg aagcagggat
     1681 cgacaaccgc ttgattttga atcgagcaat tctaggggcg aaaacacaaa aagcagatga
     1741 agcattcgct gtgaatttga ctgattggac ctacgaatta attgaaaaaa aatatgagtt
     1801 ttctggcaaa aaagagcttt atttttctgg aagagtgatc gaaagtgttc ctgcaccttc
     1861 tttagaagaa aatgtaaaag tgatccaaaa agtagccaag catcttggaa aaaaatttga
     1921 gacagaagaa tttgatatca tggctgattt gaaagaagct gtctatgata cgatagaaga
     1981 aaaaggtcgg ttggatcatg agatgattgc ggaaaaagtc ttcaaggaaa acatcacggc
     2041 aaaaatggct tttaaagaag aagtacaaga gcaaggattt gtcccagaag cacctcctgt
     2101 aaaagaagta caagaaattt ctgagaaaaa atttggaaaa caaaaattca agctatcaaa
     2161 cgggatcgaa ctgatcgtac cagtagatgt atatcgcaac ccagatttga ttgaatttgt
     2221 gaataatccg gatggtacga tatccgtgat gatcaaaaat gtggatgaag tattgaatcg
     2281 tttataaaaa tgactagaat attaggtgtt caagtaccag tgatcagtta aatgaattgt
     2341 gtcaagagaa ggatcggaaa agacgaatat aacaaaaaaa gagcgtgaga caaaagtaaa
     2401 gaacactttt gtctcacgct ctaaacacgt ataaacggcg gaagcagaag caactcct
//
LOCUS       DAFLWC010000175         2398 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.182, whole genome shotgun sequence.
ACCESSION   DAFLWC010000175 DAFLWC010000000
VERSION     DAFLWC010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.182"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            207..2069
                     /locus_tag="L1V17_002914"
     CDS             207..2069
                     /locus_tag="L1V17_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBN1237606.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2398
                     /locus_tag="L1V17_002915"
     CDS             2069..>2398
                     /locus_tag="L1V17_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBN1237607.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          865 a          353 c          466 g          714 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataat
//
LOCUS       DAFLWC010000176         2191 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.183, whole genome shotgun sequence.
ACCESSION   DAFLWC010000176 DAFLWC010000000
VERSION     DAFLWC010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2191
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.183"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            71..>2191
                     /gene="acm"
                     /locus_tag="L1V17_002916"
     CDS             71..>2191
                     /gene="acm"
                     /locus_tag="L1V17_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HBN1237608.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIV"
BASE COUNT          861 a          343 c          429 g          558 t
ORIGIN      
        1 ttgaagaaag gatttttgag agatgatata gtaggtttta tttttagtta aaatagggga
       61 gatagaaaaa atgaaaaagt gtagaaatat tattttatca atgttattta ttattactaa
      121 tataacatca ctgattcctg ttcatgtcta tgcggatgca ggcagagata tcagcagtaa
      181 tgtcacttcg ttgaccgtgg acccaacgaa tattacagat ggaggaaaca taaaagtaaa
      241 attctcgttt gacgaaaaaa aacaaaatat ccaaccaggt gattatcttt ggatcaattg
      301 gccaagtgaa ggaaatattc gcggtgaagg attccaaaaa gaaatcccat taatgattga
      361 aaataaaaat gttggaactt taacggtcag aaaagattct gcgcaggttg tgtttaatga
      421 aaatattaaa aacctagact cagtagaagg ttgggggcaa tttgagatac aggccagaaa
      481 cgtaaccgat accggtgaag aaaatacggg accattcacc gtgacgagcg gtgataaaac
      541 agctactgta aatgtgacaa agccagcttc tggttcttct tctagcgttt tttattataa
      601 aacaggagac atgctacctg aagatactaa gcacattcga tggtttttga atattaacaa
      661 taacggcact tatgttgaac aaccagttaa aatcagtgat gaaatccaaa gtggacaaag
      721 attagatcca agtacgtttg aaattaatca aatacactta ggtgaacaga aggtttatag
      781 aggagaagag ggaatccaac aatttttaca agatttcccc agcgctacat ttaatttttc
      841 agtaactgat aattacattg aaataactat accaaaaaac tttgtcaatc ttaggaaaat
      901 aatggtgagt tataagacga tcatagaaaa cccagaacaa ataaattttg agaatcattc
      961 ggaagcttgg tttaaagaat ttaataaacc tgctgttgat ggagaaagtt tcaatcatac
     1021 agttaaaaat atttcagctt ctggtggagt caacggtaca gttagaggcg aattgaagat
     1081 tttcaaatat atcaatgaca cagagattgg tatcccaaat gtgactttcg aattaagacg
     1141 agcagatgaa cagcctattc aaggacagtc tagtatcctg ttgacttcga atgaacaggg
     1201 agaagctagt atcaaaggcc tgcaagtagg agactatgtt gtaaaagaaa aagaagcacc
     1261 caattggatt gattttgatc cactaagttc aaatgaactc aaattctcca taaacgaaaa
     1321 tgatacagag ggagtcagtt tacctattta taacaagaaa aaggttacga acatcacagc
     1381 aactaaaatt tggaacggtg gaaccactcc aagaccgagt atttatttta aattattcag
     1441 agcaagtaca aacaattggg aaccagttcc tgatgcagaa acaaaacgat tagacaatgg
     1501 aataacttca gtgacttggg aagatatcca acagtatgat gatagtggaa acgaatatac
     1561 gtttaaagtg caagaagtag atcaaaacgg aaatgattat gtcccttcag gttatcaaaa
     1621 aattgaaaac gggctagtcg ttacaaatga gaataaagaa gtcatttcag tctcaggaca
     1681 aaaaacatgg gaagacaatg agaaccaaga cggcaaacga ccgacgacga tcacagtaaa
     1741 tctattagcc gacggtcaac cgatccaaca caaagaagta agtgaaaaag atgattggcg
     1801 ctatcgtttc acaaatctgc caaaatacag agacgggcaa gaaatcatct atactgtaac
     1861 ggaagacaac gtgcccgaat acagtacgac gattgacggg tataacatca aaaacagtta
     1921 tacaccggaa aaaacaaata tatctatacc aggtagccat ataacaccgt ggaaaaattt
     1981 tccagagaag acagagagag agaaaattag aaatctattc tctcaaaaat tgcaaatatt
     2041 tgctcataca ggagaatcca gcgaacaaag aagcaattat attagtaaga gagctgtacc
     2101 taaacagata acaaataaat caaaaagcat tcttcctaaa acaagtagta aaaaatctag
     2161 ttttgctgta atcattggtt tattgatagt a
//
LOCUS       DAFLWC010000177         2057 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.184, whole genome shotgun sequence.
ACCESSION   DAFLWC010000177 DAFLWC010000000
VERSION     DAFLWC010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2057
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.184"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(569..934)
                     /locus_tag="L1V17_002917"
     CDS             complement(569..934)
                     /locus_tag="L1V17_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237609.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(1010..1255)
                     /locus_tag="L1V17_002918"
     CDS             complement(1010..1255)
                     /locus_tag="L1V17_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1237610.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(1325..1579)
                     /locus_tag="L1V17_002919"
     CDS             complement(1325..1579)
                     /locus_tag="L1V17_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237611.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(1743..2048)
                     /locus_tag="L1V17_002920"
     CDS             complement(1743..2048)
                     /locus_tag="L1V17_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237612.1"
                     /translation="MPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVITLLLLV
                     MMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINPLIFSR"
BASE COUNT          760 a          355 c          366 g          576 t
ORIGIN      
        1 aattattaat tttcgtctga aaacaaaaaa agaaagcgtt attattttag tctattttca
       61 gggggggaac cttatgataa aaaaactatt tttactatca atattaacgc tagcaatggc
      121 aggttgttct gactctggct tagcaactga actgatcaca aaatcaactg aagccacgac
      181 agaggagtta aaatgtggaa acgatcacag tgactacaga ggcttaaatc gacgatgcat
      241 gggaatatta ggcagaagca attgtaagca tcgatgtagt aatcgaagaa ggtgtagaag
      301 aagcaacaga aaaatcaaaa gaaagatcaa aagaagcaat ctgtgctgtg catcgtatac
      361 agacgtcgaa gatgcggtac ttttaaacca cgtcaggaga tgttcattta tgtctaggga
      421 agttggcgat gaaccaaaac tagagtacgc ttttagtttt gcacgtgagg atgaagataa
      481 ccctaaaact tacgacattt tagcttgatc taagatggtt aaagcttttt aatgaagtaa
      541 gaggagatag aaggcttttc tagttatatt aggtaagata aattcctttt tgctccaaat
      601 ttgctaaaca ttctgctaga taaacttcat cgtgttccgg ataaatcggc acgttgcgct
      661 ctacagtagg taaatcaaaa aatgcttcgc atgatttgcc acgatacata ggatttttcc
      721 actctggtgc tgggctgtaa ccacgttttt ccatttcatc catgacaagc tgatgatatt
      781 ggaataatct ataaggagaa tagtgaaaaa cataatccac agtagcatgt ttctttcccc
      841 agccatttcc tcttaatgca cagcattccc gatgttgtcc taaaagctgt tgacgaggaa
      901 gctttgaaat caatttttca tgccataatc gcatagaaat gtctccttta tatatagatt
      961 gttaacctta gacgttaaat gaaaaaacca gcaccaaggc tggaaaaaat cacttcagtt
     1021 tgcttgctgt ttctgagcga ccaattaggt aatcaacgga aatatcgtaa aagtcagcga
     1081 tatagattaa ttcaatgatg cttggaattt cttctccttc ttcgtactta cgatatttga
     1141 ataaaggaat acttaacgcg ctagaaacag ctacttgaga taaagatcgg ccagttctta
     1201 agaaattcag acgacaacgt aaagtatcca gtaaaatagc ttcttcgata ctcatttaat
     1261 cacctttcat tatagtagaa tagttataat gactatagaa agctacacat gcaatcaata
     1321 gtactcaatg ttttttattt aaacgtatca aataaagaat gacgatcaat aaagacaaaa
     1381 ccagtcctga taattcttct ataaaaacac tatcgggttc aaagtagttg taattaaaaa
     1441 ctttccacat aaagtagata gccggaagag tcaaaatagc taaataaaac cgttctttgt
     1501 tccaattcat aagataaaca atacttgcga ccagtgcgac cgcaggcacc caaaacaaaa
     1561 ctctcaccaa cgtaatcatg taacggactc ctcaacgatt catataataa aagataacat
     1621 gttattgcat acatcacaaa tgaaatgcta ggaaaataaa agaagaatag atcaatgaaa
     1681 aatgaaaaag cagaacagtt ttctgctgat aagcaggaac tgttccgctg aatgtgtctt
     1741 atctatcgag aaaaaatcaa tggattgata tctaagtaat tcaatacata taaaaagagg
     1801 acgatcgcat tcactaaaaa ggaaagaatg atgatcccat agcgaatgga aacatattta
     1861 acaaatactt ttgtttgaat acgggcatat ctttttcctt tatagctgag catcatgaca
     1921 agaagcaaaa gggtaatcac accttgaaaa atcattccaa taaacagaat tcctgaggtt
     1981 tgataattta attggagaaa ataagctgct gccgcaacta aatcgaataa aatcgcaata
     2041 aatggcaaaa taatcac
//
LOCUS       DAFLWC010000178         2053 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.185, whole genome shotgun sequence.
ACCESSION   DAFLWC010000178 DAFLWC010000000
VERSION     DAFLWC010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2053
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.185"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..122)
                     /locus_tag="L1V17_002921"
     CDS             complement(<1..122)
                     /locus_tag="L1V17_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBN1237613.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGVNEGSS"
     gene            complement(133..330)
                     /locus_tag="L1V17_002922"
     CDS             complement(133..330)
                     /locus_tag="L1V17_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBN1237614.1"
                     /translation="MILPDKYYQVIKWTVLTVLPALSVLVATLGKAYGWNGTDMAVLT
                     INAAATFLGVITGVSAYNLKK"
     gene            complement(353..646)
                     /locus_tag="L1V17_002923"
     CDS             complement(353..646)
                     /locus_tag="L1V17_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237615.1"
                     /translation="MINLGEWGTIAGSITAIVSLILLVIRPVTASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERSR"
     gene            complement(683..820)
                     /locus_tag="L1V17_002924"
     CDS             complement(683..820)
                     /locus_tag="L1V17_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBN1237616.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEADKIISKEESA
                     S"
     gene            complement(822..1268)
                     /locus_tag="L1V17_002925"
     CDS             complement(822..1268)
                     /locus_tag="L1V17_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237617.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            complement(1265..1414)
                     /locus_tag="L1V17_002926"
     CDS             complement(1265..1414)
                     /locus_tag="L1V17_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237618.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPILNWKPKFNY
                     WEGNK"
     gene            complement(1431..>2053)
                     /locus_tag="L1V17_002927"
     CDS             complement(1431..>2053)
                     /locus_tag="L1V17_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237619.1"
                     /translation="TRTPNISEYKYRGTGMRDSNNPKDYVWDLAPEYVEDNLATDIKI
                     SEITGKANNYTDGKVSEINSQLTASINEVDTTAKDAQTKANANATAIDELDNKIDERI
                     NDTATTTLTVTNGNTGSAKLYREGKTVSIYFVALNGKSSGGNDSTILTIPEGYRPPIS
                     FEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSDYTFAITYTI"
BASE COUNT          558 a          424 c          323 g          748 t
ORIGIN      
        1 gaactacctt cgtttacacc taaattaaat tcattgttaa tcgtataggc aaacccatta
       61 atcggcaata aaaaaagagc cgttaatagg ctcatcgcag taatagtaat tttctttttc
      121 atttgtttcc tcctattttt tcaaattata agccgacaca ccagtgataa cacctaaaaa
      181 tgttgctgct gcattgatag tcagaactgc catatctgtt ccattccatc catatgcttt
      241 gcctaatgtg gctactaata cagataaagc tggcaatact gttaaaactg tccatttaat
      301 gacttgataa tacttatcgg gtaaaatcat ttcttcttaa ctcctttctt ttttaccgag
      361 acctttctct aaataaagtt ttaatttgtt gtgtgtgttc taccaatttt tctgcatgtg
      421 tatctaatct ttcatcgtgt ttctttagtt cttcatgaat catcaatcga tctgatttgc
      481 tcgattctaa atctttagtc agcaaatcta aattgtgact tacttttgaa agagtttcag
      541 taatcttcga gaaagatgca gtgactggtc ttattactaa taaaatcaaa gaaacaatcg
      601 cagtaattga tcctgcgatt gttccccatt cccctaaatt gatcatgtga caactccttt
      661 accttaaata aaaacgcatc acttaagatg cgctttcttc tttgctaatg attttatctg
      721 cttcttcgtc tgtaatgcat agtggaacga atagtcgaac ttgatcgtca gtaaaacagc
      781 cccaatcata catcattttc acatcgctaa aactaaacat actactcacc tccctttgaa
      841 gctggattta gttgctcttt aatttctgaa atgtctttgc tattttgtaa cgaagcaagc
      901 atcatttttg aattgatttg tgctaaacta tccgcttttt ctttcaatgc agtattttcc
      961 tgtttaattg ctacatcgct tagcatgagt ttggcattga tctgttttaa atcgccgttc
     1021 tcattttcta acgactcata cattgctttg agattgttta aatcgttgtg atctagtgcg
     1081 ttcgctaaaa taatccattg attcaattta ggatcaaaca tttgatcagc gattgttaac
     1141 ggttcgccat cagcacgaat tccttcaagc ggtggctgat ctgtgtaagg aacggataca
     1201 agcatgtcgt ccaatacttt tcctgcgtac tctccgccag tacgtccata tttccaaatg
     1261 tttttcattt atttccctcc cagtaattga atttcggttt ccaatttaga atcggtggtt
     1321 cgacttctgt gcattcttcc ggtaaatgtt cttcatcatt cacaatgatt tgctcgaatc
     1381 cgtaaggttc aattggtcta tatgctgcct tcatatcgat tcacgctttt ctaaatcgtg
     1441 taagtaattg caaaggtata atccgatcca taacttgagt ttcttcgcca tttaatggct
     1501 ccatctgcac caatagataa ctgagcactg ttcaaagtag aacggtctat cgagccaacc
     1561 agttgctcaa aactaattgg tggccgatag ccttctggaa ttgttagtat cgttgaatca
     1621 tttccaccac tgctttttcc gtttaaagcc acaaaatata tagaaactgt ttttccttca
     1681 cgataaagct ttgctgatcc ggtattcccg tttgtaactg ttaatgtggt agtagctgta
     1741 tcattaatgc gttcatcgat cttattgtct aattcatcta tagcagtcgc attagcattc
     1801 gcttttgttt gagcatcctt agctgtggtg tctacttcat taattgaagc agtcaactgc
     1861 gaattaatct ccgatacttt cccatcggta taattgtttg ctttaccagt aatttcagaa
     1921 attttaatat ctgtggccaa attatcttcg acatattctg gtgctagatc ccaaacataa
     1981 tcttttggat tgtttgaatc acgcatacca gtaccacgat atttatactc actaatattc
     2041 ggggttcgag tat
//
LOCUS       DAFLWC010000179         2025 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.186, whole genome shotgun sequence.
ACCESSION   DAFLWC010000179 DAFLWC010000000
VERSION     DAFLWC010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2025
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.186"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..425)
                     /locus_tag="L1V17_002928"
     CDS             complement(<1..425)
                     /locus_tag="L1V17_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBN1237620.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIP"
     gene            complement(534..1565)
                     /locus_tag="L1V17_002929"
     CDS             complement(534..1565)
                     /locus_tag="L1V17_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1237621.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
BASE COUNT          626 a          330 c          348 g          721 t
ORIGIN      
        1 ggaatctgtt ttgattttgt tccatttgaa atttctctca ctcgcttttt tgtctcatca
       61 tcaaataaaa tgaaagggtc ttctaaacga tcgataaata cttccattgt tgttgttggt
      121 agatgataag aagtcatgac aggcactgca ccaaggtaag acacagaaac agctagaagg
      181 tatgtgtcaa aagcggaact cttataaata ataactttgt ctccggattt cactccaaga
      241 tgagccaatt gataagcccg tttcaacaca ctttcgcagc attttttgta agttgtttca
      301 agtcctaatt ctgggaaagc tgaaagtggc tcatcaaaga taatcggggt ctcggaaaag
      361 ttagctgcag cttcttgaaa attcgtaaat aagttcaaag gggaatacgt tatggtctcc
      421 atcattcaca ctccattatc ttttgttaag taatatacaa attcaagata atcgtaacat
      481 aatcctttat ataataacat agtttattgt gaaaaaaaga tcatacattt gttttatatg
      541 gaagaaaccc gaacgaatgc cgctaattcg tgataagaaa aatcaaccat cttttcccag
      601 atatcttgaa aagaatggga tgagaggtat cgattaccac ataaataatt taccgcgtca
      661 gcatcatcta aatatagttc tgcataataa cgatatgttt ttctgcatag ttctggcgat
      721 acgtttttat atactgtaat tttgctcaaa atttggcgaa tagtccgagg agaaatttgc
      781 tgatcatgtg aggaacgaaa aacaaaagaa ttttcgtccg tattttgtgc tgttaactta
      841 aaatagttct ccagaaatgg catcgcttct tttggtattg gtactttatt cagtctgttt
      901 tcttttctat tcagattaag aatctgcttg gtcaaagata catctttacg tttaagttct
      961 actacttcat ggatctttaa tccgcaatac agaagaatgg cagtaattgc aaggttcctc
     1021 ggtctattct tttcttcaaa gctagcttct ctgcttgttt gaaagccttc aatcgggata
     1081 aacaaatgct caaaatcttt gaaaagttct gcatcgatat atcgcggagc tgctttggtt
     1141 gtttccggta aacttgtacc caaaagagaa atctcttctt caatcagtcc tttttgatac
     1201 aaaaatcgta aaaaatgatt taatgaatat tgcttccttg aaatcccgta atagctattt
     1261 tcaaacaatt gctccgtttc ttggttcgct gtagtttgga acgaacgagt atgtcgatag
     1321 attttagcta agaaattctg ataatcttgt ttttctaaat ggataatcag ctgatcatcc
     1381 acttcttcag aaaatacttt tctcaaataa tcagtaaaca gatgaaaatc ttttgcgtat
     1441 tcatagcgac tgcctaatga aagggaagaa cgattttctt ctaaaaactg ttgaaagacg
     1501 gaagggagca agtgtgtacg ttgctttaac ttttcttgca gttgttttct agttttgctg
     1561 tccattacaa attccctcca atagtgttca ttttctatat tttaccgcat ttcatcaaat
     1621 gaagatagac agtttgtctt gatcttagga agcaaatttt taactaagta ctagctaaaa
     1681 gatatgaagt aagaagatac atttttagtt attttattag tgcagtcatt cttttgatct
     1741 tttaattgat ttatcctctt tttagctatg tggttacttc atgagcaatg aaatggattt
     1801 ggttcgttct aatggcagga ggctctttct tttatttccg aaaaattaga aaacattttt
     1861 tcagaatcga ttggctctcc atttattcaa taatggtttg tctaacgata ttgttgggat
     1921 aattcttaaa gaagtattag aaatagttgg tacttcatta ctttacatga agatttattc
     1981 tatggtagga gcaattatat tgagaattaa tcctttttta tataa
//
LOCUS       DAFLWC010000180         2017 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.187, whole genome shotgun sequence.
ACCESSION   DAFLWC010000180 DAFLWC010000000
VERSION     DAFLWC010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2017
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.187"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="L1V17_002930"
     CDS             complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="L1V17_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HBN1237622.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLW"
     gene            661..915
                     /locus_tag="L1V17_002931"
     CDS             661..915
                     /locus_tag="L1V17_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBN1237623.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            916..1233
                     /locus_tag="L1V17_002932"
     CDS             916..1233
                     /locus_tag="L1V17_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBN1237624.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
BASE COUNT          694 a          304 c          376 g          643 t
ORIGIN      
        1 ttccaaagaa attgtttgac tcttggaaag tcacgtttta tcaatcttga gctggcactt
       61 ttataggcat tgatgaattt tgtcaattct gttttaggtt gagctttgaa cataatatga
      121 acgtggtctt tatcatgatt ccactccact aaagtaatgt gatacgattc tgaaattctt
      181 tcaaaagtag ttttggcata atcagatatt tcatcatcaa tcacttgtct acgatatttc
      241 gttactaaaa caaggtggta ataaagaaga aatactgaat gattatttgt atctaattcc
      301 atgttatatc aactcatttc ttgtatagac tgattgtaac atgggacaaa ataaaaaggc
      361 aatacgcctt agttgtcggt cttcgagtta ccaacggtaa ccctcatacc gaacggcatt
      421 catcacccac ctatagagga tgggcgactt ctgcctaatt ctgttaaatg gatgttaacg
      481 gaagtgtatg gtgagtagtt cactcgtatt ttgatatcgt ttgtatatgt tttcagcgtt
      541 ctaagtggct tattttgtcc aataataata tggagtggaa tcccttaaga aacaccgttg
      601 gcaattgttg ttataacatg ttataattta ttcatcaaaa actaaaagga gtgtgataac
      661 atgggaaaag aactaaaggt tagaaagatc ggcaatagcg tgggagtgat ccttccaagc
      721 tctcttggat taaaaagcgg agacattatc caagccaaac aagaaggcaa cttattcata
      781 ttagatacta ctcaaatagc aaaagaacac gatcgcaaat tgattgaaga aagtttccaa
      841 gactttgaga aaggtttaac agtttcagaa attgaaatgg taaaagcttt cggaaaatac
      901 ggctggagtg aatagatgaa agagtacacg ctagtttatt ctaaaagttt tcagaccagc
      961 cttgaaacga taatagaaga atgggaaaat gagcttgctc tttctccagc cagcataaaa
     1021 agatttgtag gtgcgatcca gaaggcttta gaactaacca aaaattttcc aactatgcat
     1081 gaggaagttt ccgaaatcta tggaatggat atcccaacat atcggatcgt gatcggcaaa
     1141 agctatgcct tattttatcg gatcgaccat gaaaaaaaag agatacttgt aggacgtatt
     1201 ttccaatcta aacaaatgaa actaggcttt taacaataat taggaaaaag tcgctcatcc
     1261 tctacaggtg ggtgattaat gccgctcgat atggttgtta accgtcggtt actcgaagat
     1321 tgatatataa gacttagtac ctttttattt tgctccatgt tatggccgaa ggtctaaaga
     1381 tacaatcatt agtctagaga aaaattaaga accgtaggaa ctacggggat cgcttggtga
     1441 ataagagaca ctgctattag tgaaaaaata agatatcaag tacgctctat tcccaaaaat
     1501 ttcgtgactt tactcatgag aggttcaagt agtatatttt taatcaaaat tgacgtaact
     1561 tttaataaat actacctaaa taaggtagta tttatttttg tgttttaaaa gaggaagtcc
     1621 aatatatcta tgggaaactt cttaaatatt atgttggtac atgaaaatat acatccctgc
     1681 tagactattt acaacatttt actttgtacg tattcttgtt ttaaaaggaa tgggataaaa
     1741 tataggtaca ataactattt gatgctaaat ataattaatg gaggagagat agtgaacata
     1801 cttaatgaaa aaagatatgt atggtttgct ggtaaaaaat atattactac tttcaaaaga
     1861 ttatccgagt taatgcagca gactgttaaa agtgctatgc ctgaaggata caagtttaat
     1921 tttgttcaat cttcagtatc tactgaaagt atctattttt caattctttc tgagagtagg
     1981 ctttttcatt ttagaataag ttctcatgta aagaaaa
//
LOCUS       DAFLWC010000181         2005 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.188, whole genome shotgun sequence.
ACCESSION   DAFLWC010000181 DAFLWC010000000
VERSION     DAFLWC010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2005
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.188"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            83..565
                     /locus_tag="L1V17_002933"
     CDS             83..565
                     /locus_tag="L1V17_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237625.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSTFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            762..1652
                     /locus_tag="L1V17_002934"
     CDS             762..1652
                     /locus_tag="L1V17_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HBN1237626.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT          657 a          339 c          416 g          593 t
ORIGIN      
        1 aaaaaaaagt ttttccccct aattttttta gatagaaaat tgtatagtat gatgagagaa
       61 aaagtagttt gggggaacgt taatgagaag aaaagcagta atcgatcggc tttatttatt
      121 tttttggttt tttcctatcg ttttgctacc ttttacatgg gtaaatgctg ttgtacaagg
      181 tgcggagata ttaggcctga tccaaggaag cggatttgtg gtttctagga attttccagc
      241 tttgattgtt ttctatttag tgataagtgt aggtctctta ttaccaaaat ctctgatcaa
      301 tcactacaat tggcagctgc tttacttttc ttgcttatta gtatttacat ctacgttttc
      361 tttgctgcct cgcttgatta tcggccctaa tggtttgagc gagagtggat tgaaggattt
      421 agcttattcc tccatgtatt tcttgacgat caaaccatgg ttctatttag taattgcctc
      481 atttattctt gcaacatttt tttacttctg gacagaaatc aggataaaaa gtgaacgatc
      541 tgtatctata aaaaataact attgatggtg gatcatcagt aaaaaaacat atgagctgcg
      601 taaaatgcat gtttctcata tgcttttttt attattatgt aaagaatgcg aaaaacgttt
      661 acatgatttt tacataactt aactatattt ttacagcaac catacgaggg atttacagtc
      721 gactgataaa ctttagttgt aaataagaaa ggagcaataa aatgaaaaaa gtattgttta
      781 ctctaggtat gatgggaatt cttttagccg gatgcggctc aggatcagga aatacagatg
      841 gctctgccac acaaaataat tcaagtgact caaatgaaca agtaaaaatc gttgcggtag
      901 gttcgacagc attacagccg ttagtcgatg cagcacaaga aagctttgta caagaaaatc
      961 caaattatca aatctctgta caaggaggag gaagcggaac tggtttgagc caagtcgaag
     1021 ctggagcagt tactatcgga aactctgatg tatttgcaga agaaagagac ggagttgatg
     1081 cttcaaaatt agtggatcat aaagtagcag tggtcgggat ggcaccaatc gtcaataaag
     1141 atacagatgt caaagatatc accaaacagg aattgattga tatctttaca ggaaaaatca
     1201 ctaactggaa ggaagttggc gggaaagatc aaaaaatcaa cgtcgtgaac cgtgcaaacg
     1261 gcagcggtac ccgcgcgaca ttcgaaaaat ggggactgga tggtgctacc cctgtgcagt
     1321 cccaagaaca agattcatca ggaacagttc ggcagctggt aagtcaaaca ccaggagcaa
     1381 tcagctattt agctttctca tatctcgatg attccacaca agcactaagt atcgacggtg
     1441 tagaaccaaa agaagagaat gtagcagata acagctgggg aatctggtca tatgaacata
     1501 tgtacacgaa cggaaaacct tcccctgaag tccaaaaatt cttagactac atgatgacag
     1561 aagaaatcca agaaggacct gtcaaagaat tgggctattt accaatcaca atgatggaag
     1621 tagaacgtga tcacgaagga aatatcaaat aactagcaga taaacatgcc acggtagtcg
     1681 ttactattaa ggaaaaatca actatgtttc cccacatata catttttcct ttaattgtga
     1741 aaaatagttc ctcatatttt gccgtttttt gagctaatac cgagggtcag ctgattgaac
     1801 accgtttatt cgaaaaaaag agctacgaca tagaactgtc gtaacttttt ttggctcttc
     1861 gtcaaatcgt gttggtgaag acaaatttga ataaaactta gaccgatatg cggcgcgttc
     1921 tgtgcgccgc atattttttt agttttcaaa gatcagacct tgttgtaaag gctctttgtc
     1981 aaatgatgtt ggtaaagaga aatct
//
LOCUS       DAFLWC010000182         1941 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.189, whole genome shotgun sequence.
ACCESSION   DAFLWC010000182 DAFLWC010000000
VERSION     DAFLWC010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1941
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.189"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            270..836
                     /gene="amaP"
                     /locus_tag="L1V17_002935"
     CDS             270..836
                     /gene="amaP"
                     /locus_tag="L1V17_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBN1237627.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            849..1037
                     /locus_tag="L1V17_002936"
     CDS             849..1037
                     /locus_tag="L1V17_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBN1237628.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            1050..1607
                     /locus_tag="L1V17_002937"
     CDS             1050..1607
                     /locus_tag="L1V17_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBN1237629.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            1639..1881
                     /locus_tag="L1V17_002938"
     CDS             1639..1881
                     /locus_tag="L1V17_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBN1237630.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
BASE COUNT          713 a          301 c          400 g          527 t
ORIGIN      
        1 aaatagaatc ttgtaataat aactgagcat aatctttgca atttttaatc ttgaataata
       61 tcctttaagt atagccagca atcaaaagta aatagagaat aagtaagcaa ttgttatttc
      121 agtatcagac tggcaataaa acgccgttat gatccagcaa tgtttggtag cgctttattt
      181 actgatgcta tgctaactgt tcgctatcta tactgtgatt gtcggtagag ttatttacag
      241 ggtaaaaata agtttatagg aggtggaaaa tgaataaggg gttaaaaata atcggtgtta
      301 tcatgagttt actgctactt tcagtatttc tagcgattgc gttgatcaat gcgccgtata
      361 ttatgcctga acaattggaa cgatttcgct tctttacttt aacgaattac tacatgcaac
      421 aatatatttt ctgggcagct gtagtatttg ccgttcttgc tattatcatc ttgctagtcg
      481 ttcttttcta tccaaagtca agaggaactt tcgttatgaa acgggaagat ggcaaactaa
      541 caatcgacaa aaaagcgatc gaagggttgg tacgttccca tttacacgaa gaagagttca
      601 ttcattcacc taaagtacgg atacgttcaa cgaaaaatcg aatccatatc catgtcaacg
      661 gagacttgaa acgaacttct tcattagtag ggaaaacagg tgtattgatg caagatatcg
      721 aagaagaagt aactaaagta ctcggaacaa aagaaacggt caaagtggca gtcacataca
      781 gcggttatga agaacaagaa gatacaagag actacaagca ctctcgagtg gaataggagg
      841 gccaaataat gaaagaacta ttttcagcat acaagctccc tattatcttt gggggtcttg
      901 gactactgct agctgtttta tggttaacga ttggattttt caagacattg ttgatcataa
      961 tcatgacagc aattggcgca ggaatcggtt tttatttgaa acagtcagga atagttgatc
     1021 aattttttaa atcataggag gaaacaaaga tggaaaacaa aaacatgaat acaacaaatg
     1081 gatcagtttt ggcaaatgaa aaaggagaaa accgcatgat gaatggtgaa ttgacttatg
     1141 aagacaaagt catccaaaaa atcatcggtt atgcattgaa agatgtagat ggtctattga
     1201 cattagatgg cggatttttc tcaaatatgg ctgaaaaatt agtcaacaca gataacgtaa
     1261 cagcaggtat caatacagaa gtaggtaaga aacaagtagc tgtggatcta gatgtgatcg
     1321 tagaatacgg taaagacatc gaagatattt acaaccaaat caaagaattg atcagtactg
     1381 aagtaaacaa tatgacacat ttagatgtta tcgaagtgaa tgtgaatgtt gcagacatca
     1441 aaacacaaga agaataccaa aaagatcaag aaacagtaca agacaaagta acagaagcag
     1501 caaaatccac aggacaattt gcttcacgcc aaacagataa agcaaaatct gctgtaggca
     1561 aaggtgcaca aaaagtcaaa gaaaataacg aaccacgtgt acaataagaa gtaagaagtc
     1621 agttaggagg aatttaaaat gggatttatt tgggcattaa tcgtcggcgg tatcattgga
     1681 gcaattgcag gagcaatcac gaataaagga tcatcaatgg ggatcatcgc aaacatcatt
     1741 gctggtttag taggttcagc aattggacaa gctttactag gaacttgggg accaacaatt
     1801 gcaggaatgg ctatcattcc atcattgatc ggtgcaatca ttttagtatt agtcgtttca
     1861 ttctttgcac gtaaattata agcaaattga agaaaaactt atgttgaaat gaagaacaaa
     1921 tttgagaacc gtagcgacac t
//
LOCUS       DAFLWC010000183         1925 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.190, whole genome shotgun sequence.
ACCESSION   DAFLWC010000183 DAFLWC010000000
VERSION     DAFLWC010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1925
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.190"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            72..1538
                     /locus_tag="L1V17_002939"
     CDS             72..1538
                     /locus_tag="L1V17_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBN1237631.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
BASE COUNT          590 a          330 c          396 g          609 t
ORIGIN      
        1 cttgtaagtt tgttaaaaat tgaatatgat tacatctgga taacaaattt ttatcataaa
       61 ggagagaacg aatgaacaac aaacaattac gctggtttac tgttgcgtta attgcattta
      121 acatggtttg gggcatgggg aatgtagtta ataactatgc tcagcaagga gtatcagttg
      181 tcacctcttg gctattgatt ttggccattt attttattcc atacgcattg atcgttggac
      241 aattaggatc agccttcaag gatagtaaag gaggcgtcag ttcatgggtc gaaaatacga
      301 catctaataa acgactggca tactatgccg cttggactta ctgggtcgtc catattcctt
      361 atttggcaca aaagcctcaa gcaattctga ttgctggtgg ttgggcagtc caaggaaatg
      421 gaaatatcgt aaatacgatg tcagtacaaa tggtagcagt tatttcactt attatatttc
      481 ttgccttttt atatttatca acaaaaggac tttctacttt gaaagtgatt ggcggactgg
      541 ccggaacagc gatgttcgtc atgtcgatct tatttattct tttagctgta acggcaccgt
      601 tcatcaatcc aacgatggaa tttgccacac cacatatgaa tcaagtgaaa acatatattc
      661 caacatttga tttcagttat ttcacaaccg tttcgatgct agtatttgca gttggagggg
      721 cggaaaaaat atccccttat gtcaactcta caagaaatcc tgcaaaggaa tttcctaaag
      781 ggatgatctt cttagcagca atggtaggga tttgtgctgt attaggctca gtcgcaatgg
      841 gtatgctgtt tgctagtgat aatattccta aagacttgat ggcaaatggg gcatacagtg
      901 cttttcaaat tttaggtaat tactatggta tcggtaactc attgatgatc atttacgcat
      961 tgacaaacat gattggacaa atctccgcat tagccttttc aattgatgca ccactaaaaa
     1021 tcttgttagc agatgcggat ccagaatttg taccaaactg gctacgtaaa cgtaatcgta
     1081 aaggtacatt ggtgaatggt tatcttctga caggtatact agtaggaatc attattttgt
     1141 tgccgatttt tggtatcaaa gatatgaatg aattagtaaa atggttgacg aacttgaact
     1201 cagttgtcat gccaatgcgt tacctatggg tgttcttggc atatatgatg ttgaataaag
     1261 cttataagaa attcaattct gaatataaat ttgttaaaaa tccaaaaatc ggttttatct
     1321 ttggtgcttg gtgctttgcc ttcactgcgt ttgcatgtat cctaggaatg gtgccaaaag
     1381 tagattatac tgctgatcct aaagcatggt ggttccaatt atttacgaat atcatcacac
     1441 caatcgtctt gatcttatta ggtatgatct tgccagcaat tgctcgtcga gacaaaaaca
     1501 aagaaatcac tgaaccagaa acagtggttc agccttaaaa tagaaatact tgttacaaga
     1561 ggttgtgaca gaagtggtca gcttcaagaa ataagaagga atttacgaaa attgcttctc
     1621 aaatttttgt gaagtttcgg cttgtttttc gaagaagcta cttctggaac accgtgaatc
     1681 agaggttgtg aaaaagctgt cctgcatcaa gtaataagaa cagccaaaca aaaatagccc
     1741 ctcatatttt tcgtttggct gggcttatta ccgcagatgc aagctttgga acaccgttta
     1801 aggaagaggt tgtaaaatca gcgatttgac ctgagtatta gagaaacaaa cggaaaaata
     1861 gctcctcata ttttgccgct ttttgagcta atgctgaagg tcagctgatt gaacaccatt
     1921 tattc
//
LOCUS       DAFLWC010000184         1846 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.191, whole genome shotgun sequence.
ACCESSION   DAFLWC010000184 DAFLWC010000000
VERSION     DAFLWC010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1846
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.191"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            86..1651
                     /gene="guaA"
                     /locus_tag="L1V17_002940"
     CDS             86..1651
                     /gene="guaA"
                     /locus_tag="L1V17_002940"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBN1237632.1"
                     /translation="MSSPTRFDEEPKIIVLDYGSQYNQLITRRIREFGVFSELMSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDEKAFGIDEKIFDLGIPVLGICYGMQLITYKLGGK
                     VKPAKNREYGKAELEITSAEAALFQNTPEKQTVWMSHGDLVTQAPTDFDVVATSKDCP
                     IASIQNAERKMYGIQFHAEVRHSEYGNDLLRHFTLDVCQCTGDWTMDNFIDMEIAKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHVLLRKGEAEQVMESLGGK
                     FGLNIIKVDAKERFLSKLAGVSDPEEKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGELTEEKLEIVRESDAILREEIANAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
BASE COUNT          567 a          383 c          388 g          508 t
ORIGIN      
        1 tttacaacaa ggtctgatct ttgaaaacta aaaaaatatg cggcgcacag aacgcgccgc
       61 atatcggact aagttttatt caaatttgtc ttcaccaaca cgatttgacg aagagccaaa
      121 aattatcgta cttgattacg gtagtcagta taaccaactg atcactcgcc gtattcgtga
      181 gttcggtgtt ttctcagagt tgatgagcca ccgcattacc gcagaagaag taaaggcaat
      241 gaaccctaaa ggaatcatcc tttctggcgg accaaacagt gtttatgatg agaaggcctt
      301 tggtattgat gaaaagattt ttgatttggg gatcccagtt ttaggaatct gttacggtat
      361 gcagttgatt acttataaat taggcggaaa agttaaacca gccaaaaacc gtgaatacgg
      421 aaaagcagaa ttggaaatca cttctgcaga agcggccctt ttccaaaaca ctcctgaaaa
      481 acaaaccgtt tggatgagtc atggtgacct agttacccaa gcaccgactg atttcgatgt
      541 cgttgctacc agcaaagatt gccccatcgc atcgatccaa aatgcagaac gcaaaatgta
      601 cggaatccaa ttccatgcag aagttcgcca ttccgaatat ggaaatgact tgttgcgcca
      661 ttttacacta gatgtctgcc aatgtactgg tgactggaca atggataact tcatcgacat
      721 ggagatcgca aaaattcgtg aacaagtcgg tgacaaaaaa gttttattag gcctttcagg
      781 cggagtagat tcctctgttg ttggtgttct tttacaaaaa gcgatcggcg atcaattaac
      841 atgtatcttc gttgatcacg tattgttgcg taaaggtgaa gcagaacaag ttatggaaag
      901 tcttggcgga aaatttggct tgaacattat aaaagtcgat gccaaagaac gtttcttatc
      961 aaaacttgct ggcgtgtctg atccagaaga aaaacgtaaa atcattggaa atgaatttgt
     1021 atatgtcttc gatgatgaag caaccaaact tgccggtgaa gaaggcgttt ctttccttgc
     1081 acaaggaacc ctttataccg atgtgatcga atcaggaact gaaactgccc aaaccatcaa
     1141 atcacatcac aatgtaggtg gattacctga agacatgcaa ttcaagctga tcgagccatt
     1201 gaacacattg ttcaaagacg aagtacgtga attaggtacc caattaggca tgcctgacag
     1261 catcgtttgg cgccaaccat tccctggacc aggcttaggt attcgtgtcc ttggtgaatt
     1321 gacagaagaa aaattagaaa tcgtccgtga atcagacgct atcttgcgcg aagaaatcgc
     1381 caatgccggt ttagatcgcg acatctggca atacttcacc gtcctaccag gcattcgctc
     1441 tgttggggtt atgggagatg gccgtacgta tgactacact gtaggtatcc gtgctgtcac
     1501 ttctattgac ggcatgaccg ctgactttgc ccgtatccct tgggaagtct tgcaaaaaat
     1561 cagtgtccgt atcgtaaatg aagtcgcaca cgttaaccgt atcgtgtatg atattaccag
     1621 caaaccacct gcaacagtgg agtgggaata aagagccaac ataatatgga tgaggaatac
     1681 ctataaatca acattattca attactaaag ttcctgattt tcgtaaaaaa taagatggtt
     1741 tcctaccatt ttccctacca aagcccttgt tagattaact actaacaagg gctttgcttt
     1801 tattcactac ctttattttc ctattgaatt agctttttat ctaatc
//
LOCUS       DAFLWC010000185         1815 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.192, whole genome shotgun sequence.
ACCESSION   DAFLWC010000185 DAFLWC010000000
VERSION     DAFLWC010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1815
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.192"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..122)
                     /locus_tag="L1V17_002941"
     CDS             complement(<1..122)
                     /locus_tag="L1V17_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBN1237633.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGPNEGSS"
     gene            complement(133..330)
                     /locus_tag="L1V17_002942"
     CDS             complement(133..330)
                     /locus_tag="L1V17_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBN1237634.1"
                     /translation="MILPDKYYQVIKWTVLTVLPAASVLVATLGKAYGWNGTDMTVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            complement(353..646)
                     /locus_tag="L1V17_002943"
     CDS             complement(353..646)
                     /locus_tag="L1V17_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237635.1"
                     /translation="MINLGEWGTIAGSITAIVSLILLVIRPVTASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERSR"
     gene            complement(683..820)
                     /locus_tag="L1V17_002944"
     CDS             complement(683..820)
                     /locus_tag="L1V17_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBN1237636.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEAEKIINKDKSA
                     S"
     gene            complement(822..1268)
                     /locus_tag="L1V17_002945"
     CDS             complement(822..1268)
                     /locus_tag="L1V17_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237637.1"
                     /translation="MKNIWKYGRTGGEYAGQVLDDMVMTVPFTDVPPLEGIRADGEPL
                     TIADQMFDPKLNQWIVLVNVLDHNDLNNLKAMYESLENENGDLKQLNAKLMLSDVAIK
                     QENTALKEKADGLAQINSKTMLASFQNSKDIAEIKEQLNPASKGGE"
     gene            complement(1271..>1815)
                     /locus_tag="L1V17_002946"
     CDS             complement(1271..>1815)
                     /locus_tag="L1V17_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237638.1"
                     /translation="TRTPNISQFKYFGEGLKDSNNPNDYSWDVTPEYTEKGLNDAVNV
                     YDPQRVEGLKNFADGIQIAGDKVISENDCTVYTLTKDNSQSFIDGYATFIKHGKEVIV
                     NGTVKFKKAYAFGVPLDDEVPDEFVAKIVHGMLTGPSGTSSVSKAMYVRKDLGTIITN
                     SEFAANEWFTFHGNYWVGEE"
BASE COUNT          505 a          382 c          272 g          656 t
ORIGIN      
        1 gagctacctt cgtttgggcc taaattaaat tcattgttaa tcgtataggc aaacccatta
       61 attggcaata aaaaaagagc cgttaatagg ctcatcgcag taatagtaat tttctttttc
      121 atttgtttcc tcctattttt tcaaattata agccgacacg ccagtgataa cgcctaaaaa
      181 tgttgctact gcattgatag tgagtactgt catatctgtt ccattccatc catacgcttt
      241 gcctagtgtt gcaactaata cagatgcagc tggcaatact gttaaaactg tccatttaat
      301 gacttgataa tacttatcgg gtaaaatcat ttcttcttaa ctcctttctt ttttaccgag
      361 atctttctct aaataaagtt ttgatttgtt gtgtgtgttc taccaatttt tctgtatgtg
      421 tatctaatct ttcatcgtgt ttctttagtt cttcatgaat catcaatcga tctgatttgc
      481 tcgattctaa atctttagtc agcaaatcta aattgtgact tacttttgaa agagtttcag
      541 taatcttcga gaaagatgca gtgactggtc ttattactaa taaaatcaaa gaaacaatcg
      601 cagtgattga tcctgcgatt gttccccatt ctcctaaatt aatcatgtga caactccttt
      661 accttaaata aaaacgcatc acttaagatg cgctcttatc tttattaatg attttttctg
      721 cttcttcgtc tgtaatgcat agtggaacga atagtcgaac ttgatcgtca gtaaaacagc
      781 cccaatcata catcattttc acatcgctaa aactaaacat actactcacc tccctttgaa
      841 gctggattta gttgctcttt aatttctgca atgtctttgc tattttggaa cgaagcaagc
      901 atcgtttttg aattgatttg tgctaaacca tccgcttttt ctttcaatgc agtattttcc
      961 tgtttaatcg ctacatcgct tagcatgagt ttggcgttga gctgttttaa atcgccgttc
     1021 tcattttcta acgactcata catcgctttg agattgttta aatcgttgtg atctagtaca
     1081 ttcactaaaa caatccattg gttcagttta ggatcaaaca tctgatcagc aatcgttagt
     1141 ggttccccat cagcacgaat tccttcgagt ggtggaacat cggtaaatgg aacagtcata
     1201 accatatcat caagcacttg tccagcatac tctccacctg ttcgtccgta tttccaaata
     1261 tttttcattt ttattcctcc cctacccaat aattaccatg gaatgtaaac cattcatttg
     1321 cagcaaattc gctattcgta ataattgttc ctaagtcttt tcgcacgtac atcgcttttg
     1381 atacactact tgttcctgac ggacctgtaa gcatgccatg aacaattttt gcgacaaatt
     1441 catctgggac ttcatcatca agtggtacac caaaagcata agcttttttg aactttactg
     1501 taccatttac aataacttct tttccgtgtt taataaatgt tgcataccca tcgataaacg
     1561 attgactgtt gtctttagtt aatgtataaa cagtgcaatc attttcactg atcactttat
     1621 ctcctgctat ttgaatacca tcggcaaagt ttttcaaacc ttcaactctc tgaggatcat
     1681 acacattaac agcatcattc aagccttttt cagtatattc aggtgtgaca tcccaactgt
     1741 aatcattggg attgttactg tctttcaagc cttcaccaaa gtatttaaac tgactaatat
     1801 tcggggttcg tgtgt
//
LOCUS       DAFLWC010000186         1740 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.193, whole genome shotgun sequence.
ACCESSION   DAFLWC010000186 DAFLWC010000000
VERSION     DAFLWC010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1740
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.193"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..911)
                     /locus_tag="L1V17_002947"
     CDS             complement(<1..911)
                     /locus_tag="L1V17_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HBN1237639.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYINNSSGQSVINKQIVENSDILLAIFGHKLGSPVDNYRSGTIAEIDY
                     FYKNSKGEVGVFFLDEPVPQVLAEEYIEVKKYRDSLEDKGFYGTYSKDNIRRFLTKKV
                     NYLIEKAQNNLESKRFDLDSISYKTPSVINKKVTGTDKDFDDNLDIFDPIEFDNDERL
                     LLIYAFMDENSIFSTDNSTYRKVVQWESDNNLRSYLSDRVFDVLEKLSKSGILKEEYD
                     SSFDEYPSRYILISEDYKKFKRYFLKN"
     gene            complement(1070..1336)
                     /locus_tag="L1V17_002948"
     CDS             complement(1070..1336)
                     /locus_tag="L1V17_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1237640.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            complement(1326..1682)
                     /locus_tag="L1V17_002949"
     CDS             complement(1326..1682)
                     /locus_tag="L1V17_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBN1237641.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
BASE COUNT          504 a          331 c          207 g          698 t
ORIGIN      
        1 tcatttttta aaaaatacct tttaaatttc ttatagtcct ctgaaatcaa aatatagcgt
       61 gatggatact catcaaaaga agaatcgtat tcttccttta aaattcccga tttacttaat
      121 ttttctagta catcaaatac tctatcactc aagtaactcc ttaaattgtt atcactttcc
      181 cattgaacta cttttctata agttgaatta tcagttgaaa agatagaatt ttcatccata
      241 aacgcatata ttagcagcaa tctttcatca ttgtcaaatt ctattggatc aaaaatatct
      301 aagttgtcat caaaatcttt atcagttccg gtaacttttt tgttaattac tgaaggtgtc
      361 ttgtaagaaa tagaatctaa atcaaagcgt tttgattcta aattattttg tgctttctca
      421 attaaataat tcactttttt tgtgagaaac cttctgatat tgtctttgct atatgttcca
      481 taaaaaccct tatcttctaa agagtccctg tacttcttaa cttctatata ctcttcagcc
      541 aaaacttgtg gaactggttc atctaagaaa aaaaccccta cctcgccttt gctattttta
      601 taaaagtaat caatttctgc tatagttccc gatctataat tatcaactgg agaacccaac
      661 ttatggccaa aaatcgctaa taatatatca ctattttcta caatttgttt attaataaca
      721 ctttgcccag agctattatt tatataagta ggaatcgcat tcgtttccca tcgaattggc
      781 atcaaaatta cttttgtatt atctgtattt tctatattcc atctatatat ggtttcttct
      841 acttcattcc tctttgctgc tatatcacct ggtgatgcta taaatacttt tattagattt
      901 atggttttca tttattgtac ctttctcttt atgtctcttt aaagtaattt ttgtataaaa
      961 tttattgact tttacactat aggacaactt ttatctattt agtacaaaaa ggcccactaa
     1021 actaattgat tagttaggag cctattacag gtatattttc aactcgcttt taagcaaatt
     1081 ctactaccag ctttttgcct aatgccctag cgatatcatc aagtttatcg aaagatacgt
     1141 tatcccctct ctcaattcga gcaatagtag attgagttgt atgtgctttt tgtgcaagct
     1201 ccgcttgagt taggcctgct tcctcccgtg catgataaag agcaaccgca gtttcgagtt
     1261 ttcttccttc acggtcatat gcttctgcaa aatctttgtc tttttgcttt tcttcaatca
     1321 attttttaat catcatttgt gaaccactcc tctctaagtt cttttgcatg tttaagttca
     1381 cttattggtg ttttctccgt ttttttagta aatccatggg taatgacata ccttccattg
     1441 accacatgga aatagatagc tctttggatg tttgatccta ccttacttct taattcgtac
     1501 aaattagtgt ctaatttttt cacccatttc aaccgttgag ctactagcat cccattcttt
     1561 tctgtttctt ctattgtacg taaaagcttc gcactatctt tttttggtaa tgtttccaac
     1621 cattctaaaa attcatcatg accattaggt cttttaaatg tttcaaaaga tattttttcc
     1681 atacccaatt atatcatata ttgattttat attatagtat ataacataaa aattcgaatt
//
LOCUS       DAFLWC010000187         1723 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.194, whole genome shotgun sequence.
ACCESSION   DAFLWC010000187 DAFLWC010000000
VERSION     DAFLWC010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1723
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.194"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..506)
                     /locus_tag="L1V17_002950"
     CDS             complement(<1..506)
                     /locus_tag="L1V17_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1237642.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSM"
     gene            complement(914..1618)
                     /locus_tag="L1V17_002951"
     CDS             complement(914..1618)
                     /locus_tag="L1V17_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237643.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
BASE COUNT          493 a          321 c          317 g          592 t
ORIGIN      
        1 ttcattgatt tgaactcatc catacacaac accgtcggaa ggaagttcat acgtggctgg
       61 taatgcttcg ttgcttcacg caagatccgt gtcaccgtcc catccgagac gaagtacttc
      121 ttagcgatta gtttacgtga ttgattttcg tacagttcca tgagaatcgc ctgcttcagt
      181 tcctttgtta gttgatgatg ttcatcaact aagtccgttt tcgcagaaaa ggtccgtcca
      241 caatcatggc agagaaaacg ggtacgtttt aattctaaaa tagtcaactt ttctttgact
      301 ttcaacatct gagtgcgtgt cgtataggaa ccgttgcgga taatacgaat cgatccacag
      361 tgttcacaat gggaaggtga gtcatccaat ctccctttaa taaactgcgc ttgaacgcct
      421 ttatattctt tttcaatcag ccattcttca tcaaaaaata aatgtttatc tgttaatccg
      481 agtaattttc tagtatgatt atccattgag agactccttt ggtagggtga cgttttggtc
      541 gactaaattt taccaaaagt gagtctcttt ttgagttgaa acgaagaaaa aagtgttagt
      601 agaaaatcgc tttcgatttt ccaccaacac aaaatattat agaaccgctt ttttctctat
      661 cagaaaatat gtttattatt agaatttttt atagttaagg ttaggcatct taagaaatca
      721 ggcaactcca agatatcttc aggtagaaga gaagtcgcct aacattgtag gatcataggt
      781 gatttgttgg acaggtcaag ctgatatttg agcctgatgt tagaaggaat ttctttttac
      841 ttgctgtaga aattattata tgactaaaaa ggctgggatt ttaaatccca gccttttatg
      901 acaaatagaa tttttatcga tcagtaatcg ctgtcgctgc aaattgttcg atcaaaggaa
      961 tcaaagtcaa tttgactttg tatttccgtt cgagtgcttt ttcgataacg aactcatttt
     1021 cagtagtcat agaaatagtt gctaatttac gaggttcatc agcatttttt tcattaataa
     1081 ctacttcatg ttcattttgt tctgtgtaaa atttaggata ctcagcaacg gcttttgaaa
     1141 aatcagcaaa acttaaagcg gcattcgtat cagttgagcg tgtattttca gttgtgtccg
     1201 cttttggttt ttccgttttt tcttctggca cactgactgt ttcttctgta actggtgtcg
     1261 caacagcttg cgcagttggt tcatcgtttt tcaatcgttg atcattccag taagacacga
     1321 tttcaataag aagattgtca cggaatcgtt cgaaaatccc gttttctcct gaacgaattc
     1381 tctttaatac agtattgaag ttgtcatcga ttggcacgtt gatccgtgta tcttcatttg
     1441 ttttcccagc taatccgatc gttaagattt gacggttttt gggatcaagc atgacttgta
     1501 acggcaaacc ataacgtcgc aagctctctt cttctagaga acggaataat tgtcctctta
     1561 caccatccaa tgaaggacgg aattgattta ataatttttg tttctgtttt ttcttcatat
     1621 gttctctcct tcgctcatac cctttcgatt ataagaaaaa aacagccaaa tgaaaaggag
     1681 taatgcaaaa aaacttgcgt atacgcaaat tacaacagaa aaa
//
LOCUS       DAFLWC010000188         1664 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.195, whole genome shotgun sequence.
ACCESSION   DAFLWC010000188 DAFLWC010000000
VERSION     DAFLWC010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.195"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            131..505
                     /locus_tag="L1V17_002952"
     CDS             131..505
                     /locus_tag="L1V17_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBN1237644.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="L1V17_002953"
     CDS             complement(619..1248)
                     /locus_tag="L1V17_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBN1237645.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="L1V17_002954"
     tRNA            complement(1382..1454)
                     /locus_tag="L1V17_002954"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
BASE COUNT          584 a          240 c          283 g          557 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt actt
//
LOCUS       DAFLWC010000189         1655 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.196, whole genome shotgun sequence.
ACCESSION   DAFLWC010000189 DAFLWC010000000
VERSION     DAFLWC010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1655
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.196"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            81..1604
                     /locus_tag="L1V17_002955"
     CDS             81..1604
                     /locus_tag="L1V17_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HBN1237646.1"
                     /translation="MDPTVFEAEEHIQKVIHKMFRPDNAYTKFDFRNGRPTKSAILTT
                     SSIDMAKKYYRAIKEMTKESDWLIKEFPNQPIREGRTMEDPDFPRIAITYSLEENSRD
                     SSAQQEEMQKIIEEYNQYYDTAWSLADIERYNGDINNRLARKRAEFKQFGKQIDLVIV
                     VDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTYPEKTKGLIVTFRKPATMEKN
                     VEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKEVSSMESIDEHTPLEIRIEYV
                     KAFQELNRAYESLVTYDDYNDDMVQSSTLNNQIQLLEEQIGVYETVKGSLMEEEPEKE
                     GEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSDAREEIEKALAKLNKTEGVKE
                     VYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDNLIHAFSNEWFVSEKELHASNLQYM
                     PGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMKRAWRKMLDDELIPLENELR"
BASE COUNT          608 a          269 c          339 g          439 t
ORIGIN      
        1 tagaaacata tgcagagtat tcaccggaac agatcaatcg tatgatcgat caaatggagt
       61 ctgtcaaaaa agaaagttat ttggacccta ctgtttttga agcagaggaa catatccaaa
      121 aagtcattca taaaatgttc cgtccagaca atgcctatac aaaatttgat tttcgaaatg
      181 gccgtccaac gaagtctgcg atcttaacca cgagttccat tgatatggcc aaaaagtatt
      241 atcgggccat caaagagatg acgaaagaat ctgattggtt aataaaagag tttcccaatc
      301 agcctatccg tgaaggacga acgatggagg atcctgattt cccacgaatc gctattacct
      361 attcattaga agaaaatagc cgagattcaa gtgcccaaca agaagaaatg caaaaaatta
      421 ttgaggaata taatcagtat tatgatactg cctggtcact agcagacatt gagcgttata
      481 acggagacat caataatcgt ttggcacgaa aaagagcgga attcaaacaa tttgggaaac
      541 aaatcgattt agtaatcgta gtggatcgtc tattgacagg ttttgacgcc cctacgattc
      601 aaaccctatt tgtggatcgt aatctagagt atgcaggatt gatccaagcc ttttcacgta
      661 cgaaccgtac gtatcctgaa aaaacaaaag gactaattgt tactttccga aagccagcga
      721 caatggagaa gaatgtcgag gatgcgacaa aactgtattc agaagctaaa gaagaatcgg
      781 gtttgattta tccaagttac caagaatcca aaaaaagatt caagcaagca tatggtaagt
      841 taaaagaggt ttcatccatg gaatccattg atgaacatac gccacttgaa atccgtatcg
      901 agtacgtcaa agcatttcaa gaattgaatc gtgcgtatga atcgttagtg acttatgatg
      961 attacaatga tgacatggtg caatcttcaa ctttgaacaa tcaaattcaa cttttggaag
     1021 aacaaattgg cgtgtacgag accgtgaagg gttcattgat ggaggaagaa ccagaaaaag
     1081 agggagaaga tttttcaacg atcgaatttt atagtgaaaa taccactaag ttgtatgata
     1141 ttgattctac ttatattgat caattactag gaacttatgc tgcgaatagt tcagatgcac
     1201 gagaagaaat tgaaaaagct ttggctaaat tgaataaaac agaaggagtc aaagaagttt
     1261 accgacaaat tttaaatgca tttgatgtgg ggactttaga tagtaatgaa gatatctttg
     1321 tcattaaacg tcgctatttt acacaagcaa gtgataattt gattcatgcc ttttccaatg
     1381 agtggtttgt ttctgagaaa gaattacatg cttctaatct gcaatatatg ccaggtgaag
     1441 atccaattcc taatatgaaa gcaattatca acagtaagga ttacgaagga tataaagcca
     1501 aacatccaga agcgaaacca tttaaatacc cacaagaaat gaagcgagca tggcgtaaaa
     1561 tgttagatga tgagttgatt ccacttgaaa atgaattgag gtaaacgaga agagttaaga
     1621 aaattgtacg attcaaagat agtagtaaag tggaa
//
LOCUS       DAFLWC010000190         1610 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.197, whole genome shotgun sequence.
ACCESSION   DAFLWC010000190 DAFLWC010000000
VERSION     DAFLWC010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1610
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.197"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(60..278)
                     /locus_tag="L1V17_002956"
                     /pseudo
     CDS             complement(60..278)
                     /locus_tag="L1V17_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(544..738)
                     /locus_tag="L1V17_002957"
     CDS             complement(544..738)
                     /locus_tag="L1V17_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237647.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            complement(838..924)
                     /locus_tag="L1V17_002958"
                     /pseudo
     CDS             complement(838..924)
                     /locus_tag="L1V17_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
BASE COUNT          569 a          242 c          214 g          585 t
ORIGIN      
        1 ggtattttta ttatatatag atttaacata tgtcggtcgg ttgattgata tagctaaagt
       61 tataactcaa ccgaagccga ttcatctaca cgaataaagt tgcgagtgtt ctcggctaat
      121 tcataaaaat tgttatgtgt tccatatagc aatactggaa taactttatt ttcttgaatc
      181 tcataagcaa ctctatacac ggtgaccgca tacttaaatc cattagacca attacctgat
      241 aaacctccag ttttttgctc ttacttaaat ggatcaatgg caatttcatc acaaacctat
      301 agaggatgag tgacttctgc ctaattacgt taaaaaatat tgaaagtaac tctatgtagc
      361 aaaaaatatc tagaatttca tttcctcaaa actgatcgat attgtatcta aaaatatata
      421 ctacctaaaa taggtagtat atattaaaat atgtgctttt gttagaaaaa tcaatacata
      481 aattatcata tctgtatatg tcatttaggt atttcagtta tgttataata gttttgctgt
      541 ctgctacccc ggcctaatct ggcaagggga ggaggagata taatgaaata cctttttgat
      601 tttgtttttg caatcaagcc acttgcagat gtagtgtgca gttacctctg caaatggctt
      661 gattgcaaaa ttgccaaaaa agacagtaag cctacccgtt aattctataa tatagaaacg
      721 taaaaaaaac cccatcagcc tgcacgctga tggggtttgg tgatataatg aaatacctct
      781 ttgttactca taattatacc ataattagtc acgaatgcaa ccaatagaaa aaactactta
      841 gaacggtaga tcatcgctaa taacaatgca ttgtccacca aatggatttt gtgaagcatt
      901 aaatacattg ttattaattg tcgctgcttt taactaggcc tctccccttc tattataaaa
      961 gaagatatat atcatttctt aattacctac taccttaaac caaaatttaa gtactaccta
     1021 atttaagtag tacttaaaca atctaaaaaa tagttatccc aattgttatg cttttataat
     1081 acgattattt gtaacaaaat gaatattata taattaaaca ctaccatatt taggtagtgt
     1141 ttaattatta gcaaaacaaa aaatatttat tctattctct taacttcaac taagttatgc
     1201 tgcacacctt tatataaatc atatgcaact cattagctag acaaactaca agcatgtagt
     1261 tttatctgtt aattatgtac tacctaaata aagtagttta taattagcaa gtatatatat
     1321 ttaaaaattt aagattaatt tttttatgac ttgtacaaat ttatctgata ttctcttatt
     1381 aagaactacc taatttgggt agttcttatt ttttacattt taagtagtat ttaattgcaa
     1441 tttggtagta tttttttatt atcttattct tagaacggta gtacttaata taaatatagg
     1501 tagtatctaa tttaagtatt aatggtagta tctaaattaa caggtagtat gtaactactt
     1561 taaagtaatt tttttcagat taacacagta gtatcttatt aaataagtta
//
LOCUS       DAFLWC010000191         1609 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.198, whole genome shotgun sequence.
ACCESSION   DAFLWC010000191 DAFLWC010000000
VERSION     DAFLWC010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1609
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.198"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            780..>1609
                     /locus_tag="L1V17_002959"
     CDS             780..>1609
                     /locus_tag="L1V17_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBN1237648.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     "
BASE COUNT          574 a          222 c          245 g          568 t
ORIGIN      
        1 gtaattccta attttgctcc acttttagat aatttttagg tctatttaac tcatcagaca
       61 ttctatgctc atttttctcc aaatttgttt caactctttc gtacttaatt ttgcgtattt
      121 gaaaattctt cttttagagt acttttatta cgatactagt atgatatata tctatagcaa
      181 acagttaaaa tcttcctaaa ataagcgaat agcattccta aaacctataa aatttttaga
      241 tgaagcgaca agtggacaat taataaacta cttgaacatg aaattatgga tcacctttca
      301 aatttagaaa atggaattct tatacttatt gcgcaacatt tattgattgc aaaattatgt
      361 gacaaaaaaa actagtagaa gaaagaataa tggcttgata ataaagtact acctattaaa
      421 ggtagtactt tatttaattt agtataaatt aacatactac tatattttag gtttcatatt
      481 atataaatta ataatatact accatttgtt ggtagtataa tttaaaggta ataagttatt
      541 cttttattac tatgtttggg ttttatagca aagaaagttt aataagagtt tggacctagc
      601 aaacaatatt aatgaggtca ttaaatctta ttatctttag tgatataacg aaatatctac
      661 acagacaaaa tgatagcgta aaatattttg tgtaaataga tatttagggt agaaaaaaag
      721 aaagtccatt ctgtaaaatt aaagttacca caaccgaaat tttataggag gactttctca
      781 tgcccaattt tactacagaa attatggaaa cactaatcaa taaaggtgat ttagatgaat
      841 tatttcgatg tcatttagaa ttagctgtta attcattatt gcaggctgaa ttaacagctt
      901 ttcttgatta tgaaaaatat gatcgtgctg ggttcaattc aggtaattcc cgtaatggga
      961 attattcacg ttcattcaga acagagtatg gagaattaaa tttggtaatt cctagagata
     1021 gaaatggtaa gttttctcaa caaactttac ctgcttataa aagaaccaat gactctttag
     1081 aaaccactat tattcagcta tttcaaaaag gaattactat gtctgaaatc tctgaattga
     1141 ttgaaaaaat gtacgggcat cactatacgc cacaaaccat ttcaaatatg actaaaatag
     1201 tttctgaaga tattattgcc tttaaagaaa ggtccttaga atccagatac tctgtcattt
     1261 ttatggatgc tactcacatt cctttaaaaa gacaaactgt ttcaaaagaa gcagtttata
     1321 ttgtaattgg cattcgatta gatggaacca aagaggttct tgggtttagt cttgctccaa
     1381 ctgaatctgc ttatgtttgg aaagagattc ttcaagacct aaaagaccgt ggtttaaaag
     1441 aggttttatt agtcgtaact gatggtttaa gtggcattaa cgatagtatt catagtgttt
     1501 atccaaatgc tcaatttcaa caatgttgtg tccatatatc tagaaatatc gctcataagg
     1561 ttcgtgttag tgatcgacaa gaaatctgta gcgatttcaa attagttta
//
LOCUS       DAFLWC010000192         1539 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.199, whole genome shotgun sequence.
ACCESSION   DAFLWC010000192 DAFLWC010000000
VERSION     DAFLWC010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1539
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.199"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            25..1491
                     /locus_tag="L1V17_002960"
     CDS             25..1491
                     /locus_tag="L1V17_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBN1237649.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT          423 a          289 c          326 g          501 t
ORIGIN      
        1 atttaaagaa ttggggtata gattatggaa aaacagcaag acaagggctt cttcgggcag
       61 ccgaagggat tgtcaacttt gttcttcact gagatgtggg aacgatttag ttattacggt
      121 atgcgtgcat tacttatcta ttatatgtac gatacagttg ccaacggggg acttggatta
      181 ccacgagcaa cagcattagc tatcatgtcg atctacggat ctttgatcta catgtctagt
      241 atcgtcggcg gatgggtatc tgaccgagtg ttaggagcaa aacgcactgt attcttcggt
      301 ggagttttca ttatgcttgg ccacatcgtc ttggctttac catttggtgt aagtacattg
      361 tttgtttcga tggcattgat tattatcgga accgcctttt tgaaaccaaa tgtttctggc
      421 atggtcggac atctttattc aaagactgac ttgcgaagag atgcaggatt ttcgattttt
      481 tacatgggtg tcaacttagg ggcattatta gcaccactaa tcgttggtac aatcggtcaa
      541 gaatataact atcatttagg gttctcttta gctgctattg ggatgttctt tggattatta
      601 caatacatca tccaaggacg caagacatta gacggagtgg gtacaacacc gccgaatcct
      661 ttgacaactg aagaacgtaa aggattcatc cgtaacttga tcatcgcact tgttgttatc
      721 gctgcagtat tcggcggggc acaactaact ggtcatctga caattgactt ttttgtcaat
      781 acaatcagtg tattggggat tatcttaccg ttgtattact ttatcaaaat gctgacttca
      841 aaagatgtaa ctgctgaaga aaaaccaaga gtatgggctt atatcccatt attccttgca
      901 gcaatcattt tctggtcatt acaagaacaa ggttcatcta tcttagcttt atttgctagt
      961 gaacgtacac aatctacgct atttggtgta acgatccaag caagctggta tcaatcattg
     1021 aatccaattt tcatctttat tctgacacca gtattcgtaa cgatgtggac gaaacttggt
     1081 gaacgtcaac catctacagt agtgaaattc tctcttggac ttttatttgc aggattatcg
     1141 tacttgctat tgatgttgcc gggtatgctt tatggtacaa gtggaaaagt aagtccattg
     1201 tggttgttgg gaagtttctt catcgtggtt attgctgaat tgtgtctttc accagttggt
     1261 ttgtctgtga caacaaaatt agcaccacga gcatttgaat cacaaacaat cgctatttgg
     1321 ttcttagctg atgcttcttc acaagcaatc aatgcacaaa ttgcacgctt ctacacaccg
     1381 ggaacagaat ctgcttactt cggtattatc ggtgcagtag caatcgtcgg tggtatcttg
     1441 ctatttactg tgaaagaacc aatcaaaaaa ctaatgggct ctattcatta atcaatgaac
     1501 ataaaaacag gaattgctta tttgcagcag ttcctgttt
//
LOCUS       DAFLWC010000193         1499 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.200, whole genome shotgun sequence.
ACCESSION   DAFLWC010000193 DAFLWC010000000
VERSION     DAFLWC010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1499
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.200"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            20..442
                     /locus_tag="L1V17_002961"
     CDS             20..442
                     /locus_tag="L1V17_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237650.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            452..655
                     /locus_tag="L1V17_002962"
     CDS             452..655
                     /locus_tag="L1V17_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237651.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            866..1450
                     /locus_tag="L1V17_002963"
     CDS             866..1450
                     /locus_tag="L1V17_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1237652.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT          533 a          218 c          282 g          466 t
ORIGIN      
        1 gatttcgagg tgatagacaa tgaaaaataa gtttatttta tctttaggta ttttaactat
       61 tggaattagt gtaactggaa ctacaattcc tacatttgct gatagtacaa atgaaccaac
      121 tactgtagta gataataacc aagaattaac tcctttagat aggaacggaa tagccattgg
      181 taacccaact aacgacttaa ctgttactga aaattattta atagtttctc cattacttgc
      241 tcgagcagct tctaaaacga tacgagtgac aggaacgatg atttttgata aagttggttg
      301 gccttctaga cctcctcaat cacggaattg gaaagaaaaa agaaatggtt attggtacta
      361 tggaaaattg tatttacaaa gttataaatc agctggaaac aattggattg cgacttattc
      421 aggaacctta actagaaagt agggattttt tatgccagaa tttgtgaaca caccaaattt
      481 ttatcaagat agcgatattc taagtaaaat taatttaccg aaagaagaat cagctttaca
      541 agttcagcga actttacagg agacacaaaa aattcaaaaa tcaatttcta atctagaaga
      601 ttctgaagaa aaaagaaaaa aaagagacca aaaaacatat caaaaagaaa aataatgatt
      661 ttaaaaaaag agtgtctagt cgacattctt tttttctaat tgaaagtgtt cataaaatca
      721 cccatttctg gacactttct ttttttgctt tatttttcaa aaaaacaatt catttcatgt
      781 tcataaaccc ataacaatat ctatgttcag ttaaactata tggataaagt tatgttacaa
      841 taaaattaat gaaggagtga tttttttgaa aataggatac gcccgggtat ctactggttt
      901 acaaaatttg gatttacaag aagacagcct aaataaattt ggttgtgaaa aaatttttac
      961 tgatcatatg agtggggcaa aaagtaatcg accaggatta gaaatggcca ttgattttgt
     1021 tcgctctggc gatacacttg tcgtttggcg cttagatcgt ttaggtagaa atatggaaga
     1081 tttgatttca atcgtcaatc gactgaatga gcgtggtgtg agttttcata gtattcaaga
     1141 aaatattacg atggacaaat caagttctac aggacagctc atgtttcatt tgtttgcggc
     1201 atttgcagaa tttgagcgta atttgatcct ggaacgatcc gcagcaggac gagcagctgc
     1261 tcgtgcaaga ggacggtttg gtggtcgtcc tgaaaaattg tctgaacaag atttggaatt
     1321 actgaagact ttagtggata gcggtacacc tattaagact attgcggaac ggtggaacgt
     1381 ctcaagaacc accatttatc gttatttggc aaaaatggag gagaaaaatg gaaagacaaa
     1441 ttctcattag tttttgtcat ttaatgctga aaatttttgc catttatcta gaaaagtga
//
LOCUS       DAFLWC010000194         1495 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.201, whole genome shotgun sequence.
ACCESSION   DAFLWC010000194 DAFLWC010000000
VERSION     DAFLWC010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1495
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.201"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..613)
                     /locus_tag="L1V17_002964"
     CDS             complement(<1..613)
                     /locus_tag="L1V17_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1237653.1"
                     /translation="MDNHTRKLLVLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCYDCGQTFSAKTDLVDE
                     HHQLTKELKQAILIELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTHQLFTILEDRRLYKLTQYFL"
     gene            901..>1495
                     /locus_tag="L1V17_002965"
     CDS             901..>1495
                     /locus_tag="L1V17_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBN1237654.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKK"
BASE COUNT          526 a          214 c          283 g          472 t
ORIGIN      
        1 gcaggaagta ttgagttagt ttgtaaagtc tgcgatcttc aaggatcgta aatagctgat
       61 gggttgtccc atcaacacaa ataaaactca tggaaccaga aacagacttc attgatttga
      121 actcatccat acacaacacc gtcggaagga agttcatacg tggctggtaa tgcttcgttg
      181 cttcacgcaa gatccgtgtc accgtcccat ccgagacgaa gtacttctta gcgattagtt
      241 tacgtgattg attttcgtac agttctatga gaatcgcctg cttcagttcc tttgttagtt
      301 gatgatgttc atcaactaag tccgttttcg cagaaaaggt ctgcccacaa tcatagcata
      361 gaaaacgggt acgttttaat tctaaaatag tcaacttttc tttgactttc aatatctgag
      421 tacgtgtcgt ataggaaccg ttgcggataa tacgaatcga tccacagtgt tcacaatggg
      481 aaggtgagtc atccaatctc cctttaataa actgcgcttg aacgccttta tattcttttt
      541 caatcagcca ttcttcatca aaaaataaat gtttatctgt taatacgagt aattttctag
      601 tatgattatc catagagcga ctcctttggt agggtgatgt tttggtcgac taaattttac
      661 caaaagtgag tctctttttg agttgaaacg aagaaaaagt gttagtagaa aatcgccttc
      721 gattttccaa caacacaaaa tattatagaa ccctttattc taaaggattt caaggtgtct
      781 gtttgcattt attagaaaaa agaaaaagta ttggcaacag aaggtgtcac caacactaga
      841 tattatagag ccataatatg ctgtataata tctagtgtat aggcttaagt ggaggtatat
      901 atgaaaatat taactgttga agatgataat atgataagag agggaataag tgaatatctt
      961 tcagaatttg gatatactgt tattcaagct aaagatggaa gagaagcctt gtcaaaattt
     1021 aatagcgata taaatttggt tatcttagac attcagatac cttttataaa tggtttagaa
     1081 gtgttgaaag aaattagaaa gaaaagcaat ttaccaattc taatcttgac tgcatttagt
     1141 gatgaagaat ataaaattga tgcatttact aatttagtag acggatatgt agaaaagcca
     1201 ttttcattgc cggtcttaaa agctagaata gattctttaa ttaagaagaa ttatggacat
     1261 ttagagaagt ttgaatataa ggatctatcg gttaatttta atagctatac agctaaaata
     1321 aatggtgaag aaatagatgt aaatgcaaaa gaactagaag tattaaaatg tttattggat
     1381 aataatggac aagtgttaac aagaatgcaa attattgatt atgtatggaa agatagcgaa
     1441 gaaactcctt atgatcgagt aatagatgta tatataaaag aacttagaaa aaaat
//
LOCUS       DAFLWC010000195         1480 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.202, whole genome shotgun sequence.
ACCESSION   DAFLWC010000195 DAFLWC010000000
VERSION     DAFLWC010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.202"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            64..972
                     /locus_tag="L1V17_002966"
     CDS             64..972
                     /locus_tag="L1V17_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HBN1237655.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDLQGVR
                     HESISERFLSDLNYLYQKMKAALFTIEYGEIEVTDILQDDLFSDNHEVEKIETVEFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            972..>1480
                     /locus_tag="L1V17_002967"
     CDS             972..>1480
                     /locus_tag="L1V17_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237656.1"
                     /translation="MVKVKRMMETDESGVKRQFMPITHVSAVLGLEKMISGQSKVLSV
                     NGKYGAVILTKADLGLENAITELPYASETSDGILTAEMFQKIVNGEGGTYILPIATPE
                     QLGGIKVGELLEVTEEGVLSATKQTDFNFSEELKGKLESLKILKAGANISIAEDGTIS
                     STGGSGTGGV"
BASE COUNT          529 a          197 c          316 g          438 t
ORIGIN      
        1 cagtattata gtgcaagtgc aatttcttcc attgtcatac caccaaaata gggaggtgat
       61 ttaatggcaa agtggaatgt catattaagt acaacagaac cctataatta cgtggggatg
      121 attcaagttc gacaaggcaa taaaaacact gaagttatgg aagctacaat tgtcgaaaat
      181 ggtcttccat atgatttatc agaatgtaag gtatattttg aatcagttgt tggcggaaaa
      241 tatccagtcc aattagaaac aaaaattgtg gatgctaaaa aagggaaaat caaatatatt
      301 tttgataaat attccatgca gtgtttgcat cgacaaacag ccaatttcat tatatttaaa
      361 ggagaagact tgattggaac aactcaagac ttctcttatt ttgtcatcaa tgctgtttca
      421 aaaacagaag gagaaatggg ttcttattgg caatcaattg aagatttaat tgctgatatg
      481 acagatttta ttaatgaaaa taaaggcgat tttacggact ggatgaatga aaggaaagaa
      541 gaatttgatc gctggagaga ggaacaggag aatagtttcc aagattggag agaaggacaa
      601 gaatcagatt acttgtcatg gtttgaatca atcaaggata ttttgaagtc tatcgatcca
      661 ggtggagtaa tgttagccga attaatggat gcacgtgtag atcttcaagg tgtacgccat
      721 gaatcgattt ctgaacgttt cctatccgat ctaaattatt tgtatcaaaa aatgaaagca
      781 gcacttttca cgattgaata cggtgaaatt gaagtgactg atattcttca agacgatctc
      841 ttttcagata atcacgaagt cgaaaaaatt gaaacagtag aatttccaat tgaagaagga
      901 gctttgatta ttgcaactgt tgatgatcca aaacagaatg ttttcactct tgagaaagtt
      961 ggggtgattt gatggttaaa gtaaagagaa tgatggaaac tgatgaatct ggtgttaaac
     1021 gtcaatttat gccaattaca catgtctctg cagttttagg cttagaaaaa atgatatcag
     1081 gacaatcaaa agttctttcg gttaatggta aatatggtgc agtcatttta acgaaagctg
     1141 atttaggatt agagaatgca attactgaac taccttatgc aagcgagaca agcgatggta
     1201 ttcttactgc tgaaatgttt caaaagatcg taaatggaga aggtggaaca tatattttgc
     1261 cgattgctac tcctgaacaa ttaggaggta taaaagttgg ggaactctta gaagttactg
     1321 aagaaggtgt tttatctgca actaagcaaa cagacttcaa tttctctgaa gaattaaaag
     1381 gaaaattaga atctctaaaa atattaaaag caggtgcaaa tatatcaatt gcagaagatg
     1441 gaacaattag ttctacaggt ggtagtggga ctggtggtgt
//
LOCUS       DAFLWC010000196         1449 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.203, whole genome shotgun sequence.
ACCESSION   DAFLWC010000196 DAFLWC010000000
VERSION     DAFLWC010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1449
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.203"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(141..1052)
                     /locus_tag="L1V17_002968"
     CDS             complement(141..1052)
                     /locus_tag="L1V17_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBN1237657.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
BASE COUNT          403 a          266 c          209 g          571 t
ORIGIN      
        1 gattctaagt aaaaaaaatt tttaaaataa aaagaactaa atcaagtagt aattaaacta
       61 ctgttgattt agttctaata aaaagattta gatgaacagt tttattgatt taaatagttc
      121 atatttttta tttataccgc ttatttacta cttgctgtac tagaatctga agtgaatgta
      181 ctcaaaacat tttcaaagtc tttgtctttg atttttacat tagcgtcttt caatacttcg
      241 ccaattactt tattctggaa ggtactgtca cttaattttg tgtctgttgc aatttctttc
      301 aattcttttt tgtatttatc catgtcgttg cctttgtttt ggtttttcac cattttaacc
      361 acataatatt ccgtagtata agttgaagca ttggtagaag tgatcacatc agaaacttga
      421 ccatctttca acttaaaggc tgcttctttg acttctgccg gaaccgttgt agtagtggaa
      481 tcaaatttca cttttccgcc atcttctttt gtcgtagtat cagttgactt gtctttggct
      541 aatttagaga aatcgtctcc cttatcagca gctttcttca catcttttgc atcatcttca
      601 cttgctactt ggataatttg agcttccact tctggatgga aagattccca agccgttttt
      661 aaatcttcat cggtcaattt gatatgtttc tttagacctt cttgaaaggc tagactttgt
      721 ttgatactgt ctttgaatgt ttgttctgtg taacctgcag atttcaattg tgaatcaaat
      781 gaatcaccca attgtttctt tgtttgatca tattgagaat cgatttcttt ggttgatacg
      841 tcatctccat atttatcttc aaatacttga taaacgatca actgttgcac agcggaatct
      901 gctccttgca tttttttcaa gctatccatt acttcttgtt cgctgattgt accgccttta
      961 taactaacgg ctgttttttc accggcattc gtacagcctg acaataagcc agtgcctagt
     1021 acgatggcaa gtgctaaaaa tctttttttc atttatcaat tctcctactt ttcgtttttt
     1081 gcgaattgct aaaaacaaag gtgttcaaga tgaaaatcat caagaacacc tttactaatc
     1141 tgctcgatac gtcctgaata gatataaggc tacacaatcc agaaagttcg ctcagcagaa
     1201 taaatgtcaa gtagcacatc acaccttaat atactacttc ttttgttacc gtttttcaag
     1261 tctatcttgc gttccgtatt taacgtaact aattcttaga acaaatgtta tcgattttgt
     1321 ttttcttctt ccgctgctgg gatattcaaa tcagacactt ttatgttcga ttttccagac
     1381 atttttttgt tgtttttatt atgatatatt tttatacaac taaaaatgaa tatattaaaa
     1441 ctaccaaaa
//
LOCUS       DAFLWC010000197         1430 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.204, whole genome shotgun sequence.
ACCESSION   DAFLWC010000197 DAFLWC010000000
VERSION     DAFLWC010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.204"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..916
                     /locus_tag="L1V17_002969"
     CDS             <1..916
                     /locus_tag="L1V17_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HBN1237658.1"
                     /translation="KEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGLLNKLTI
                     SNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITEEKEQQK
                     AIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKELYANKIQ
                     ELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEPMDRIKE
                     LSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLDEIEKVV
                     LENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            988..>1430
                     /locus_tag="L1V17_002970"
     CDS             988..>1430
                     /locus_tag="L1V17_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBN1237659.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQDMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRR"
BASE COUNT          621 a          168 c          225 g          416 t
ORIGIN      
        1 aaaggaatat attattgacg atgctgtttc tgtccctctt attttaaata aacgagagaa
       61 aaataattta aagaaaaaaa tgctcattcc atttgattca gaagtgaaag gattactcaa
      121 taaactaact atttctaata tagactcgac tagggaaaaa atcataaaaa tatttgataa
      181 aattaataat ttattcaaga atgacaatgc tgaattaagg aagggtcttt tagagtttaa
      241 acttcaagaa ctagaacttc attactctta tttagtgaaa attaccgaag aaaaagaaca
      301 acaaaaagca ataaaagaac agatgataga agaggaaaaa gttcgtagag aaattgatcg
      361 tgaaaagaaa cgtattgata aagaacaacg tcaattcaat tctgaaattt ccaaattaat
      421 cgcatatatg caaaaagcta atgcagatgt ggaaaaagaa ttatatgcaa ataaaattca
      481 agaactggaa gaaaaattaa aagaattaga agttatacgt gaaaatgtat tacaaagaga
      541 attaaatact agagccggtt atgtgtatgt aattagtaat attgggtctt ttggtgaaga
      601 catatataaa attggtatga ctagaagatt agaacctatg gatagaataa aagaattgag
      661 tagtgcatcg gttccatttg aatttgacgt tcatgcgatg attttttcag aggacgctcc
      721 gtctttggaa actaaattgc ataatcattt tagaaaacaa gaagttaata aaattaatca
      781 aagaaaagaa tttttcaaag tttcactaga cgaaatagag aaagttgttt tagaaaatta
      841 taatggaaca gtaacattta caaaattagc taaagctgaa caatatagac gatctttaga
      901 attgtcaaaa gattaaatat ataaaaagcc ttcgggcttt ttcttttaac aattaatagg
      961 aacgtatatt cgaaaggaat agaaataatg tggttagaaa aaataaatga caaaaaattt
     1021 aagtacaccg aacgttatac ggatccctta actgaaaaaa agagaaaagt gtccgttact
     1081 ttatctagca attcacgcca agcttggaat caagctaact tacttttgaa tgaaaaaatc
     1141 gcagaaaaaa taaaacgaaa tgaagaatta ccactaactt ttggagaatt aaaaactaaa
     1201 tgggatgaaa aatacaagcc aactgtaaaa gaaagttcct atcgaacaac tcaggtttat
     1261 ctatcattaa tttcaaaata tataaaagat gatgtacttg taaaaaacgt taatagtaat
     1321 cttatacaag atatgctaga ttactactat tttgaaaaaa atttatcata taattatgta
     1381 atacatttaa aaacttttac aggaatgatt tttaaattcg ccaaccgtcg
//
LOCUS       DAFLWC010000198         1424 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.205, whole genome shotgun sequence.
ACCESSION   DAFLWC010000198 DAFLWC010000000
VERSION     DAFLWC010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.205"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(150..1337)
                     /locus_tag="L1V17_002971"
     CDS             complement(150..1337)
                     /locus_tag="L1V17_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HBN1237660.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DAFLWC010000199         1421 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.206, whole genome shotgun sequence.
ACCESSION   DAFLWC010000199 DAFLWC010000000
VERSION     DAFLWC010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1421
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.206"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            36..446
                     /gene="spx"
                     /locus_tag="L1V17_002972"
     CDS             36..446
                     /gene="spx"
                     /locus_tag="L1V17_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBN1237661.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            460..816
                     /locus_tag="L1V17_002973"
     CDS             460..816
                     /locus_tag="L1V17_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HBN1237662.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT          523 a          208 c          267 g          423 t
ORIGIN      
        1 gtagaattgg attataatta aaaaggagtg agaaaatgat aaaagtatat acttcgccta
       61 gctgtacttc ctgtagaaaa gcaagagcat ggttgcaagc gaatcaactt gaatttgaag
      121 agaagaatat ttttgccgaa ccgttaacag aaagtgagat caaaaagatc ttggcagcga
      181 ctgaaggagg agttcaagat attatttcca ctcggtcgaa aatttacgaa aagctgggca
      241 tagattttaa cgaattaact ttaaagcaaa tgatcgtctt attcaaagaa tatccttcat
      301 tattgagacg acctattttg attgatgaaa aaagaatact aatcggattt aatgaagatg
      361 agatccggtc atttgtccct cgtgaaattc gatgtgttgc cagaaatctg atctatttac
      421 aaaacaataa catcttaaat tcatagggag ggagccttcg tggaagtgaa agtctatgga
      481 tcagcgcact gtgtaacaag tctgaaggcg aaacaatggt tagaacacca tcaattgcct
      541 tatcaatttg ttgacttaga agaacgcgat ttaagtacag aagaagcaga agaattatgc
      601 agttttgaag aagtgcaagc agaacagcta tttgcgactt ggtctgaggc ttttcacaac
      661 attgcgattg acctttcctg tgtaggaaaa aaacaactga tttttttatg cacacaacat
      721 accaatctcc tcagacgtcc tttgattatt atcgatgaag ttctatttat tggatacaat
      781 gagcagttga tggaacagct tatcttaaat aaatagactt taactgtttt aatcaagtca
      841 ctgagcattt catacagttg taacagtcga acacttagca tcaagcgtgt tatgtgttct
      901 ttttttgact ttatttttct actatagaga catgctcaat ttatgtggtc aaaattcaaa
      961 tctaggtggg gatatagagt taaaaatata ttgacatgtg taaatttaca tgatatattc
     1021 atttctgttg ttttaagtag caaagcaata aaatagtatt ttaaaaaaca tataaaatag
     1081 ttgttgacat gttagaaatg acatgataag ataactgagt tgttaaaaaa gaaccacttg
     1141 tgaagcttga ttctatcgaa aaaaacttca aaaaagttct tgacaaataa caaatgataa
     1201 gttatgataa atgagttgct gtaagatttc gaaaaacgaa atcaaaaaaa cttttaaaaa
     1261 agagttgaca attacttgtc tctctgatat gatataaaag ttgctacggc agccaaaaac
     1321 gaatcgggga acactcctga tgaagtagac ctttgaaaac tgaacaaagt aagacaaacc
     1381 aaatgtgtag ggcgtcttga ttcaattcaa gacaacaaac a
//
LOCUS       DAFLWC010000200         1417 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.207, whole genome shotgun sequence.
ACCESSION   DAFLWC010000200 DAFLWC010000000
VERSION     DAFLWC010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1417
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.207"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(149..448)
                     /locus_tag="L1V17_002974"
     CDS             complement(149..448)
                     /locus_tag="L1V17_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBN1237663.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            799..>1417
                     /locus_tag="L1V17_002975"
     CDS             799..>1417
                     /locus_tag="L1V17_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBN1237664.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQ"
BASE COUNT          480 a          226 c          200 g          511 t
ORIGIN      
        1 tgttaattaa aggataaaat acaatataaa gaaacatctg tttctttatt tagaataaaa
       61 aaatacagac tctgttcaaa taaatgaacc tagcctgcat tatgagattg actatacttt
      121 ttaattcatt gagatgaata actcgttttt ataaatgccc aaaagtaatc ggtgccgaag
      181 ccattcctcg acctaattct ttttcaaatt ttcctattgt tgatatctcc atataaaacg
      241 gtgatactgg tttagacaat tctcccctga ttgctaacgg acgtaaacta cgttccaaat
      301 tatttatgac tttaggataa tactgacctt tttctaagcc tgtctttgcg tctatcaaaa
      361 gtatacgttc cttttctttg atctctggat ttaaaacgag atcatataat tttagtacca
      421 tgttttctat ttcttcactt ttagacatca cgatttcctc ccaaaaatat atttcttccc
      481 actacattct ataaacaaag tatacgctac atctagattt ttttaaatca ttactggatt
      541 gttaaaacct ttcaatacac tgttatggca acgattttta ttttaaaaac attctaaatt
      601 aaatcagtaa aaatttttat tctaagattt ttattagaat tacgcctaat ttgtgtctct
      661 cagggcaatt ctaagaacgt ttcaagagat agcgacacta tcgttatcga aaaaggcgaa
      721 aacctatctc attttctgct aatgtaagtt ggtttagctt ttgttaatat gactttatga
      781 aaatggaggt aattaaatat gatttttcct aaagttaatg aagcaagctt gaataaagga
      841 tccttttttc atatctatga aaacgaagat tttgaactgt ataatatcct ttcacaaaaa
      901 gaggtcatcg aaaaccaaat aatctgccat ccaattattt acaaatctat tttcaagtat
      961 gcattttttg cttccaatga ttttcaaaga atggagatta ccgactgtat attcgaaaac
     1021 tgtgattttt caggctgtat attgacaaaa agcatgttgc atcgcgtgaa atttgtcaat
     1081 tgtaaattaa caggtactaa attgatggaa agttatattg ggaacacgtt attcgagaat
     1141 tgtaaaatgg actatgtaaa tttatctggt tcaaacataa aagaaagtac ctttgagcac
     1201 tctgtcttat caagcgcaga ttttgtagac tgttccctca ctaaaataat gttttctact
     1261 aatgatttag aaaatgctag cttttttgat actgatttaa aaaatatcga tttaagtagc
     1321 aactcctttg aaatgattga agtacgctcg gaacatctaa aaaattgtac gcttaatcag
     1381 ttgcaagcac ttggttttgc tagaaaattt ttacaaa
//
LOCUS       DAFLWC010000201         1385 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.208, whole genome shotgun sequence.
ACCESSION   DAFLWC010000201 DAFLWC010000000
VERSION     DAFLWC010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1385
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.208"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(140..1288)
                     /locus_tag="L1V17_002976"
     CDS             complement(140..1288)
                     /locus_tag="L1V17_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1237665.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSS
                     GKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQ
                     RKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDI
                     ICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICS
                     ECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
     gene            complement(1305..>1385)
                     /locus_tag="L1V17_002977"
     CDS             complement(1305..>1385)
                     /locus_tag="L1V17_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBN1237666.1"
                     /translation="FCLLTTGGAPIDVIKKYIQNQGNNHK"
BASE COUNT          403 a          246 c          220 g          516 t
ORIGIN      
        1 taaacctgac ggttcttaac gcttgaagtg ggagcttctt gggaatagag catacttgat
       61 agcgtatttc tttactaaca gcggtgtctc ttatttacca agctatcccc gtagttccta
      121 cggttcttga tgattggatc taagccaatc ccatagaatg tagtcttaga ccttcggtca
      181 gaatattgat actagcattg atatcacgat catgatgagt atgacaaaca ggacaagtcc
      241 attctcgaat ttcaagagat ttcttgccat ctttatgtcc gcactctgaa caaatctgac
      301 tagacggaaa ccatttatct actttgatga tttttcgtcc ataccagtca gccttgtatt
      361 gtaatttagt cacaaacttt gaccaagaaa catcagaaat acttttagct aatttatgat
      421 ttcgcaacat accttttgtg tttaagtctt caatacagat aatatcgtga tttttgatca
      481 tttctgtact caacttattc agaaaatcag tacgttgatt cattactttt tcatgcaatc
      541 tagctacttt gcgtttttgt ttttgataat ttttagcttc aaatagattg gtacctttat
      601 ttttagccaa taaagcacgc ctagacaatt tgcgttgttc acgctttagt ttcttttcca
      661 ttttggacgt gaatttatta ttatcaattt tttgtccatc agaaagaatc gcaaagtcca
      721 taatacctaa gtcaatacca attgtggaat tagttttagg taattcgata atttcttctt
      781 tacacaacaa agaaatatag tatttaccgc tagaatgacg tgatattgta gcagatttga
      841 taatcccttt tggttgtcta tgaagcttaa ttcttactaa tgacttcaat ttaggaactt
      901 tgatgaattt actatcaatc aaagcaactg taccattttg attattcgtt gtataactct
      961 gaacaggatt tttcttactt ttgaaacgtg gaaatccaac ggatttatcc cgaaaaaaat
     1021 tcttgtatgc tttatctaaa ttaagttggg cattggctaa agcaaggcta tcaatttctt
     1081 tcaaaaacgg aaattctttc ttgtatttag ctggtgtcgg aaaagtcatt tttttagaag
     1141 aatcattttt aacttcttca tacgcctttt ttcggtcatc aagcattaga ttgtagacct
     1201 tacggacaca accaaaagat ttggcaaaga agatttcttg ttcctctgtt ggatagattc
     1261 tgaatttgta tgcttttagt tgttccataa agttcaccta ctttctattt atgattgttt
     1321 ccttgatttt ggatatactt cttaatcaca tcaattggtg cgccaccagt tgtcagaaga
     1381 caaaa
//
LOCUS       DAFLWC010000202         1380 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.209, whole genome shotgun sequence.
ACCESSION   DAFLWC010000202 DAFLWC010000000
VERSION     DAFLWC010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1380
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.209"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            97..711
                     /locus_tag="L1V17_002978"
     CDS             97..711
                     /locus_tag="L1V17_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBN1237667.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            complement(735..1085)
                     /locus_tag="L1V17_002979"
     CDS             complement(735..1085)
                     /locus_tag="L1V17_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBN1237668.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(1079..1342)
                     /locus_tag="L1V17_002980"
     CDS             complement(1079..1342)
                     /locus_tag="L1V17_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HBN1237669.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
BASE COUNT          436 a          261 c          225 g          458 t
ORIGIN      
        1 taccctaact agacacgacc gcgacattga aaaatctggt tttctcgtgt atgattaggg
       61 tgttttttaa atagttgcag aaagtaggta aaaattttga gagttgcata catacgtgtc
      121 tcatccatcg atcaaaatga acaacggcag attgaagaaa tgaaaaaatt cggtgcagag
      181 agaattttca ttgagaaaca atctggcgca acgattactc atcgacctgt ttttcaagaa
      241 gcactggatt tcgtccgaga tcaagatatt tttattgtgg aagctattga tcgacttgga
      301 agaaattacg acgagatcat cgcttcagtc aattacttga agaagaaaaa tgtgcagctg
      361 atcatcacaa gtctaccgat catggccgaa gcaattggca atcctctcct ggataaattc
      421 attaaagatt tgatcattca aattttggcc atgatcgctg aacaagaacg taccgaatct
      481 aaacgacgtc aggcacaagg cattaagatt gcaaaagcga acggtgttta taaaggacgt
      541 cctaagctat acagtgccaa tgcaaaagat ccccaacgtc gtcttgttta taaaaacatc
      601 gttgaggatc taaaaaaagg tgttgcgatc gctaagattg caaaagacta caatgttacg
      661 agacaaaccg tatatagaat aaaaaaagac agcatggtca atcacgaata gttgatcatg
      721 ctgctgtttc tattttattt gcttactttt tgaaaaactg ttctaacttt catcaataac
      781 tcctcaacta aactatcatg cgctttttcc aaaaaaatac actctctggc ttcataatca
      841 attgtcgtta gttgatctaa taatactttt cctgttgtct tcatttcata ttctgagttt
      901 atatttacat atagcggata gtttctagtt gtactagaaa ttggagcaac tgtaacaacg
      961 ttactataat ccgcaataat atcatgactt aaaacaatat aaggtctttt acctgtctgt
     1021 tcgtgtccag atcgaggtgc tgtattcaat aatagaatat cgccttgtct aggttttctc
     1081 accatttttc attacctact gcttcaccta aattttgaat cgtcacatga tttctttcat
     1141 cagtgtaatt ttcaaataac tgttcaattg ttaattcatt ttctatatta gccgcttcga
     1201 taattagccg cttctgaccg tttacttctt cttgtattat cttcactttg tcttctgtat
     1261 gaattccaag atattccata atatactttg gcaatctaag gccattacta tttccccatt
     1321 tttttatagg taacatttcc atagtagaca cctctttctg tatatacata gtataacata
//
LOCUS       DAFLWC010000203         1364 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.210, whole genome shotgun sequence.
ACCESSION   DAFLWC010000203 DAFLWC010000000
VERSION     DAFLWC010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1364
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.210"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            82..>1364
                     /locus_tag="L1V17_002981"
     CDS             82..>1364
                     /locus_tag="L1V17_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HBN1237670.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQL"
BASE COUNT          465 a          262 c          257 g          380 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat taat
//
LOCUS       DAFLWC010000204         1363 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.211, whole genome shotgun sequence.
ACCESSION   DAFLWC010000204 DAFLWC010000000
VERSION     DAFLWC010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1363
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.211"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            103..1335
                     /locus_tag="L1V17_002982"
     CDS             103..1335
                     /locus_tag="L1V17_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBN1237671.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
BASE COUNT          444 a          258 c          301 g          360 t
ORIGIN      
        1 aaataacctc ctttttttat ttaaagcctc attgtttgaa tcataattaa atggtatcat
       61 gctaatagtt accagaaaaa atggtgagga ggaattttta ttatgttatc tgattttaat
      121 gaacttctaa aaaaatatgc acgcttaatt gcagaaactg gcgtagccac agaaaaagga
      181 cacacagttg ttttacagat cagcgtggaa caggcacccc ttgctcgatt gatcacacaa
      241 gaagcttata aactaggagc cgctgaggtt atcgttcaat ggactgacga ccagatccaa
      301 agagaatttc ttttacatgc tgcaacggat cgtattgaga atgtaccaca atctaaaatc
      361 gatcaagcgg atgaatggct tgaaaaagga gcaagcagga tcagcgttgt ttctgccgat
      421 cccgatgcat ttgctggtgt agatagccat cgagtagcgt cttatcaatc agcgaatggc
      481 aaagcactaa tgaatttacg caaggcaact caagcaaata aagtcagttg gactgtcgtg
      541 gctgcggctg gtaaacaatg ggcagcaaaa gtcttcccag aactgccaga agaaaaacaa
      601 gttgaggcat tatgggatca gattttcaaa acgactcgtg tctatgaaga agaccctgtc
      661 ttagcatgga agaagcatga tgaaaaatta gcaaaaaaag cagaagaatt gaatcgagaa
      721 caattttctg cccttcacta tactgctccc ggtacagata tcattatcgg attgcctaaa
      781 aaccatcttt gggaaggcgc tggaagctat aatgctcgtg gagaaaaatt catggcaaat
      841 atgccgacgg aagaagtgtt cacagcacct gacagtcatc gagtagatgg ttacatttca
      901 agtacaaagc cactgagtta tgctggcacc atcatctcgg gtatgaaatt tacttttaaa
      961 gatggaaaag ttgttgattt ttctgccgaa caaggagaag atgtcttagc aaaactgctt
     1021 gatacagatg aaggtgcgcg tcgtttagga gaagtcgcac ttgtacctga cccttcacct
     1081 atttctcaat ctggcatcat ctttttcaat acattatttg atgaaaacgc atcgaatcac
     1141 ttagcactag gttctgctta tgccttcagt gtgaaaggcg gtacagaaat gtccgatgaa
     1201 gaattagcag aagctggatt gaatagaagt caaacccacg tagatttcat ggtaggatct
     1261 gacaagatgg atatcgacgg aatccgtgaa gatggctcta cagtaccgat tttccgaaat
     1321 ggcgattggg cttgagtata ctttcgcaca catgcaaaaa ata
//
LOCUS       DAFLWC010000205         1355 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.212, whole genome shotgun sequence.
ACCESSION   DAFLWC010000205 DAFLWC010000000
VERSION     DAFLWC010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1355
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.212"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..1355
                     /locus_tag="L1V17_002983"
     rRNA            <1..1355
                     /locus_tag="L1V17_002983"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          362 a          295 c          415 g          283 t
ORIGIN      
        1 caagctgtga tggggaggga aataatagta ccgaagttcc tgatgtcaca ctgccgagaa
       61 aagcttctag tgagaaaaca gcggcccgta ccgcaaaccg acacaggtag tcgaggagag
      121 aatcctaagg tgagcgagag aactctcgtt aaggaactcg gcaaaatgac cccgtaactt
      181 cgggagaagg ggtgctgatc atacgatcag ccgcagtgaa taggcccaag cgactgttta
      241 tcaaaaacac aggtctctgc aaaatcgtaa gatgaagtat aggggctgac gcctgcccgg
      301 tgctggaagg ttaagaggag tgcttagcgc aagcgaaggt acgaattgaa gccccagtaa
      361 acggcggccg taactataac ggtcctaagg tagcgaaatt ccttgtcggg taagttccga
      421 cccgcacgaa aggcgtaacg atttgggcac tgtctcaacg agagactcgg tgaaatttta
      481 gtacctgtga agatgcaggt tacccgcgac aggacggaaa gaccccatgg agctttactg
      541 tagtttgata ttgagtgtct gtaccgcatg tacaggatag gtaggagccg tagaaatcgg
      601 aacgctagtt tcgatggagg cgctggtggg atactacccc tgcgttatgg ccactctaac
      661 ccgcaccact aatcgtggtg ggagacagtg tcagatgggc agtttgactg gggcggtcgc
      721 ctcctaaaag gtaacggagg cgcccaaagg ttccctcaga atggttggaa atcattcgaa
      781 gagtgtaaag gcagaaggga gcttgactgc gagaccaaca agtcgagcag ggacgaaagt
      841 cgggcttagt gatccggtgg ttccgcatgg aagggccatc gctcaacgga taaaagctac
      901 cctggggata acaggcttat ctcccccaag agtccacatc gacggggagg tttggcacct
      961 cgatgtcggc tcgtcgcatc ctggggctgt agtcggtccc aagggttggg ctgttcgccc
     1021 attaaagcgg cacgcgagct gggttcagaa cgtcgtgaga cagttcggtc cctatccgtc
     1081 gcgggcgttg gaaatttgag aggagctgtc cttagtacga gaggaccggg atggacttac
     1141 cgctggtgta ccagttgttc tgccaagggc attgctgggt agctatgtag ggaagggata
     1201 aacgctgaaa gcatctaagt gtgaagccca cctcaagatg agatttccca tttctttaag
     1261 aaagtaagat ccctgagaga tgatcaggta gataggtcag gagtggaagt acagtgatgt
     1321 atggagcgga ctgatactaa tcgatcgagg actta
//
LOCUS       DAFLWC010000206         1311 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.213, whole genome shotgun sequence.
ACCESSION   DAFLWC010000206 DAFLWC010000000
VERSION     DAFLWC010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1311
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.213"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            102..>1311
                     /locus_tag="L1V17_002984"
     CDS             102..>1311
                     /locus_tag="L1V17_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBN1237672.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVL"
BASE COUNT          412 a          258 c          252 g          389 t
ORIGIN      
        1 ggtgaacttc accaacatct tttttgtata aaaaaatata gaaaagacac cctgaaatcc
       61 tttagaatta atttggctac caattcatag gaggattcaa gatgtctcat actcagctta
      121 tcaaagatac cctaaatatt ctagacctaa atatctattt cgaggaaaat tgtttaacta
      181 aagaaaaata caaagggcaa atttgcttga tttacaaagg aactcttctg tacaagccag
      241 aagagtgttc ccattgtctt tgtgtcgtcc cctctaggat cattcgttgg gggacgacaa
      301 ccgttcggtt gttactgaat gatgtgtctg agtatcgcac ttatctggag ctgaagaaac
      361 aacgatttaa atgtaagtct tgccaaagaa cattcgtagc ggatacctct gttgctgaaa
      421 aacactgttt cattagtcaa aaagttcgtt ggtctgtcat tgctcgctta aaagagaata
      481 cttccatgac ggaaatcgct cgtcagaaaa atatttccac ttcttcggtc tatcgtgtca
      541 tgaagcgatt ctaccgccca ttgaatcctt tcaaacagac tttgccaaag gtcttatgct
      601 ttgatgaatt caaatcggtt cgaagtgttg ccagtgcaat gagttttatc atgatggacg
      661 gacaaagcca tgcattattg gatattgtcg aaaatcgacg cttgccttat ttagaacgct
      721 atttttctcg gttttcatta gcgactcgtg aagccgttca attgattgtt attgatatgt
      781 atgcgcctta tgtttcgttg gtgaaaaagc ttttcccgaa tgctcagttg atcatcgatc
      841 gtttccacat cgtccaacat attggcagaa ctttcttgaa tcatcgagtg aaagaaacca
      901 cggtacgact taaaggaaat tcccactctc aacgagggtt agggaaaaaa ttgaagcgct
      961 attggaaact cctacaaaaa gaagaagcaa agttaaacta tgaaaaacgg gtttggcgtg
     1021 ccagttttaa agattatttg actgaaagtg agattgccga tcgactgtta gctgcttgtc
     1081 ccaacttacg ccaaggctat cagttatacc aagacattct ttatgcggta aagaaaagag
     1141 atcagtcact atttgaggat tgtttaacta gagacattag cggtctgcca gaaacctata
     1201 caaccacttt acgaacgttt aaaaagtttc tgccacagat ccaaaatgcg cttcactaca
     1261 gctattcaaa cggaccattg gaatgcttaa acaaccacat caaagtatta a
//
LOCUS       DAFLWC010000207         1303 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.214, whole genome shotgun sequence.
ACCESSION   DAFLWC010000207 DAFLWC010000000
VERSION     DAFLWC010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1303
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.214"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            502..1035
                     /locus_tag="L1V17_002985"
     CDS             502..1035
                     /locus_tag="L1V17_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HBN1237673.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
BASE COUNT          421 a          239 c          242 g          401 t
ORIGIN      
        1 tattaagagg ttgtgaaaaa gctgcactgc atcaagtaat aagaacagcc aaacaaaaat
       61 agttcctcat atttttcgtt tggttggact tattaccgca gatgcaagct tttgaacacc
      121 gtttattgag aagttgtgaa atcagcgtcc tgacctgagt attagagaaa caaatggcaa
      181 aatagttcct catattttgc tattttttga gctaataccg agggtcagct gattgaacac
      241 cgtttagtgg agaagttgtg aaaaagtcgc ctactttcga gtcgtaagaa atttttttga
      301 aaatggttcc tcacaacttt gcataaattt gacttaatac cgagaagtca tgatccccat
      361 ctaactccaa atcacaagga atgagttcaa aaactagctt ttctcaacaa atattacata
      421 aaaaattcta tgttttttgt taaatttatt tgcttttttc aaaagtatgt tacagtaatt
      481 tcccaaggag gttttacaga aatgaatttt gttgccatgg attttgaaac tgccaatcat
      541 cagccttata gtgcttgttc tcttgcgcta gtcatggtaa aaaatagcca gatcgttgat
      601 gaattctata cattgataca gcctgagact ccttttttct ggcgaaatgt ccaaattcac
      661 ggaatccatc aagaagacgt acgcaatgcg ccgaaattcc cagaagtctg gcaaactatc
      721 caaccatatt ttcaaaaaaa tcgtttagtc gttgcacata atgctgcttt tgatacaaag
      781 gtcttagcgg gatgcttaga ttattatcat cttgaacagc ctaattatct ttctttatgt
      841 acagtgaaaa gtagccgtcg cctgtttcct gaatttccaa atcatcgatt gaacactgtg
      901 tgcgaaaatt tgaacatcca attagatcat caccatgatg cattggaaga tagtcgtgca
      961 tgtgcggaaa tcctgcttta tcaagaaaaa aaattcggga cagatccatt gaaaaaactt
     1021 gtgactataa agtaaaagaa tacttatgaa acacacaaag aggtcgtgag cctgccgttt
     1081 cactccgagt cacaaggagc aatttcaaaa aatagcttct catgtttatt aaatattgtg
     1141 actggtgacc gaggagctgg caggagaaca ccgtttattg gagaggttgt gaaaaagctg
     1201 ttctgcatca agtaataaga acagccaaac aaaaatagct tctcatattt ttcatttggt
     1261 tggacttatt accgcagatg caagcttttg gacaccgttt acc
//
LOCUS       DAFLWC010000208         1298 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.215, whole genome shotgun sequence.
ACCESSION   DAFLWC010000208 DAFLWC010000000
VERSION     DAFLWC010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1298
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.215"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(840..>1298)
                     /locus_tag="L1V17_002986"
     CDS             complement(840..>1298)
                     /locus_tag="L1V17_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HBN1237674.1"
                     /translation="YILEFETIPEELKDKRVEEVDRTPAENLAYQVGWTNLILKWEND
                     ERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKELEEILNRNIDDINMMIDSMSD
                     EDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTFRTKIRKWKRLAL"
BASE COUNT          404 a          257 c          195 g          442 t
ORIGIN      
        1 ggtatttaga taacacgaaa gaataaaaat aacagctgat agtaaagttt gttgacgatt
       61 gctactcaat cgaaagtgag ttagtgcgta tgaacttgct tctgaaaact tatgaaatga
      121 aagacctttt acatcttgca gaaatcgtta ctgggattaa actaagcaat aaaaactaat
      181 gttcccctca ttctttgaac ttctactatt tgatttattt attctgataa atgacgattt
      241 caccttcagg atcttcaaat cccgtataga atttatttaa gatctcttca gtatcagtaa
      301 taggataggc gataggccac ataccctttg atggttagaa taaactgctc aaaatctgta
      361 tcgtatgttg gctttagcat attaacaaag gctatctcca aattataaac cataagcgtt
      421 gaatcgttct taacaatttc aattcttcct aacccaaagt cagaagatat aattaccgga
      481 cttgccttac ccttcatgtg ggttgttgag attccatatt taaagggaat tgtcggtact
      541 atcggcggtc tgaaaaacat cccaaaaata aaaaaatctt tcccctgcta gtctcctaag
      601 tccctttgta gcggatatgg caccataatc tcattttatc gaagtgagtc atggtttatc
      661 tgttggccaa ccaaaattga tacaatctaa cgatgcaccc tctacggcat tctaggggag
      721 tgcacttgca ttcacccaat aaaaaccggc agttagcaaa gaacttatgt agtcgtatgt
      781 tcttactgtt aacatacaag aggtctcctt tccacaattg cttagcagta aacgggaatt
      841 tacaaagcta atctcttcca ttttcttatc tttgttctaa aagtcccaaa tggagcaact
      901 gtatttacat gaataaattt atatacttcc catacagccg ttttggttgc ctcgtctgcc
      961 cattttcttt tgtgtgcagt gaatagatct tcatcactca ttgaatcaat catcatgtta
     1021 atatcatcaa tattacgatt gagaatttcc tctaattctt tcaatggtag atgtgcatag
     1081 gtatttgtaa accacttata taactctcct aactgattcc atttaaattg atcagaaggc
     1141 gttttaacag ataatccatt tctttcatca ttttcccatt ttagaattaa attcgtccaa
     1201 ccaacttgat atgctaaatt ttcagcaggt gttctatcca cttcctcaac tcttttatcc
     1261 ttcaattctt caggaatagt ttcaaattct aaaatata
//
LOCUS       DAFLWC010000209         1270 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.216, whole genome shotgun sequence.
ACCESSION   DAFLWC010000209 DAFLWC010000000
VERSION     DAFLWC010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1270
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.216"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(46..119)
                     /locus_tag="L1V17_002987"
     tRNA            complement(46..119)
                     /locus_tag="L1V17_002987"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(83..85),aa:Ile,seq:cat)
     gene            complement(308..1267)
                     /locus_tag="L1V17_002988"
     CDS             complement(308..1267)
                     /locus_tag="L1V17_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HBN1237675.1"
                     /translation="MNGFAYTINNEFNLGANEGSSQVANNQYILLHETANETATGRNE
                     AQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGSYANANSPVQIELQHTHDKAT
                     FEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHLWVTQNIWGDHTDPYGYLSEM
                     GVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNYAHIDQFGEIEN
                     ANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRADVNQAYNTSGNVGYHVSF
                     NMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
BASE COUNT          353 a          260 c          239 g          418 t
ORIGIN      
        1 tcttcaaaaa attctaacac agaacgattc aaatggctac gttaatgtac cctgtaggac
       61 tcgaacctac gaccggacgg ttatgagccg tctgctctga ccaactgagc taagggtact
      121 ggttgttgcc acataaagcc ataaacaatc aaccagtaga atgtgtggca acaaacctgt
      181 tatcgcatag cttggagtgt gactattatg ggtgatagtg aagatatgcg ataacatcac
      241 tattttatcg aatgattttt atagttgtca atatagttat gtaatgctcc tcaacgagga
      301 gctattttta tcgtttagga atatttaaat accaacgttt gtcatggaaa tcttgcgcac
      361 cgcctttagt gtttccctct ggatcattcg ttgcccgcat catgacatag actttcttat
      421 tagggaagtt acgcatgtta aaagatacat gatagccaac atttccagaa gtattataag
      481 cttgatttac atctgctcta taaattccat cagctcttac tcgagctaat tctttcccag
      541 tattgtaatc cataatgaag atatactcgt atttatagtt agcaatgtgc catccagcta
      601 catgcaaatt tgcattttcg atttctccaa actgatcaat gtgggcgtaa ttcgttccat
      661 ctgtcagtgt aggattagct gcaccagctc gtgttggatc aatgacaggc ttgttttcag
      721 aagttgttgg attttcatcg gtaaatccat gagctaaatc atatgctaat ttttctttac
      781 ttacgcccat ttcagaaaga taaccgtaag gatctgtatg atcgccccag atgttttgtg
      841 ttacccataa atgcgatttg attcccggtt ggttataagg agtgtccaac gttaatggaa
      901 taccatattt cattgctgaa tctctagcca attcaacgta tgccttgtag tttttctcaa
      961 acgttgcttt atcatgtgtg tgttgtaact caatctgcac aggactgttg gcattagcat
     1021 acgaaccagc accgtactgt acataaccag gttgaccgac ttgataaaca attccgccgt
     1081 ctcccacaat ataagcagta taagcgctag tccatgaacg ttgcatatac tgcgcttcat
     1141 tgcgtcctgt tgctgtttca ttagccgttt catgcagtaa aatatactga ttatttgcta
     1201 cttgtgagct accttcattt gcgcccaaat taaattcatt gttgatagta taggcaaatc
     1261 cgttaattgg
//
LOCUS       DAFLWC010000210         1264 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.217, whole genome shotgun sequence.
ACCESSION   DAFLWC010000210 DAFLWC010000000
VERSION     DAFLWC010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1264
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.217"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            130..1170
                     /locus_tag="L1V17_002989"
     CDS             130..1170
                     /locus_tag="L1V17_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBN1237676.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
BASE COUNT          513 a          179 c          205 g          367 t
ORIGIN      
        1 tctgatttta ggtagtattt aattaaaaaa cagttttaat gcgtttgcat tttttattta
       61 tctttgctat tttcgaaaag agtaggtaat tttacataaa taaaacaacg tgaaagtaga
      121 ggatctacaa tgactgattt taaatttttt aaggcggata gagtttacaa cgaattattt
      181 tatcaatttc caaaagtctt tattgtttct gacgaataca aaaaaatgaa agattcaact
      241 aagattgcct atatgctttt aaaagcaaga ttagagatcg caatcagcaa acggcaaatc
      301 gatgaagaag gtaatgttta ttttacttat acgacaaatg aactatgtag agtattaaac
      361 tgccaaaaac aaaaagcgat agcaatcaaa aaagagttgg aatcctttgg tttattatta
      421 caaaagcaga tgggatttaa caaacagtta gggaaaaata atcctaatag actatatcta
      481 gcagaattaa aagtctcaga aaatgatatc tacttactcg aaaaatttga tagagagaat
      541 agggaaaacg ttgataaatc agagggtatg aaaatcatac ccaccctcga cgaaaaatca
      601 gacgctgaat cccttggggc tcaagagggt atgaaaatca taccgtgcca aaacgttgat
      661 aaatcagagg gtatgaaaat cataccagaa cttaataata atatattaga cactaataga
      721 cacaatatag acactgaaaa agaccgccta caagatcaat tgttgttaga caattttgag
      781 acaattatga caaacgacag cattgctacg tttgtccctg aacgagtatt aaatttgata
      841 aaaacatttt cttcaagtta cagtgaagct caaaaaaccg tccagactat tcataatgca
      901 aagaaaaaag ctgaaataga aagtgatatt tcgatagttt ttgaagaact cgatagttat
      961 tatgtcaatg cagaacaaga attatacacg acactgttaa aagcctatca aaaattaaaa
     1021 accgaaaaag tcgaaaatat ccagaacctg atttttgtct atgtaaaaaa ttggtttatc
     1081 gaaaaaccaa tagctgctaa agtatcaagt gaaaaacgtt tgaattatgc aagctcccca
     1141 agcactatta cgaaagactg gttagagtga aactttactg acaaagtgat tgttgcttca
     1201 tggagtaaca ttaaaattaa aaatttttta ttattctaat tatattacga atattacaaa
     1261 ataa
//
LOCUS       DAFLWC010000211         1244 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.218, whole genome shotgun sequence.
ACCESSION   DAFLWC010000211 DAFLWC010000000
VERSION     DAFLWC010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1244
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.218"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(214..363)
                     /locus_tag="L1V17_002990"
     CDS             complement(214..363)
                     /locus_tag="L1V17_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237677.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            825..1037
                     /locus_tag="L1V17_002991"
     CDS             825..1037
                     /locus_tag="L1V17_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237678.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
BASE COUNT          463 a          187 c          206 g          388 t
ORIGIN      
        1 aatattatca tcgaaacagc taacaaaatt gtcataaaaa acgagatggt tgatattaga
       61 acttgtgttt ttgtttaggt ctagagataa agagagacaa tttccaaata tatgtaatga
      121 atacaaaaag acgtttgtcg cggattaccg ttacaaacgt cttttattga ttttccgaga
      181 tctcatcagt cgccatttgg aatggttcac tccttatcta gattcgttta atgctcggac
      241 tgcttgttcg attgtaatac caaacgcaac gttattttcg ttttgtgcat caatcgccat
      301 aaaacggtta gaagttgtat caaaagctac gcggtattgc atatttgttt ttgtaaacgt
      361 cataaaattc atctcctttg taatgtaatt tagttcttga aagtttcctt taaactttcg
      421 aacttatacc aagtttagca tcgtacgttt tttgatgcaa ttaaaaagca tttatcattt
      481 tccttattta ttttttctta aatggtttag ctattttctt ttaatccgat aagtagccca
      541 atcatcaagg ttacaaatac tattgcttga atataaatca tatgctcacc tctttataaa
      601 taacttagca atataaagaa aaaaacgcac gaacaacata ggaatataaa caaacgtttt
      661 tgtcacaacg tctaagatcg tgttaaaaaa tagttatcta aaaagcagaa agatactcaa
      721 aataaaaaat aaaaaaatgg ataaaaacgt tttcaaatac aaggtaattt gttattataa
      781 aataaagaaa aaacaaaata aaaataaaga aaagagggaa tgaaatggta aaagcagaag
      841 taggaagatc ttatatatgc aaaccgatcg gagtatctca tgaactaatc ggctgtattg
      901 aacgtacata tatcaacacg gctgtcgtgt atgttgaaag ttatgaccaa cgagactatc
      961 aacttatcaa tgaaagcaag tatcgcatgc tcgtaaaatt ctgtgatatt agcgcacctg
     1021 ctgaattggt ttcttaaaca gtatttttga gaattcgcaa gaactccctt ataatataaa
     1081 taaagacaga agggagcgag aagatatgcc aaaaagaaaa agttcaggga aaatgggaat
     1141 tattcttgca gtgatctctg caattcctgc tattttagct attgttcgtg cgatgaagga
     1201 atcaagagaa agttaagcac acattatgag cgtcaaacaa aaaa
//
LOCUS       DAFLWC010000212         1219 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.219, whole genome shotgun sequence.
ACCESSION   DAFLWC010000212 DAFLWC010000000
VERSION     DAFLWC010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.219"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..460
                     /locus_tag="L1V17_002992"
     CDS             <1..460
                     /locus_tag="L1V17_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBN1237679.1"
                     /translation="LLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTTLFVSV
                     IYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGLLPKFM
                     KVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            469..696
                     /locus_tag="L1V17_002993"
     CDS             469..696
                     /locus_tag="L1V17_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1237680.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT          377 a          195 c          204 g          443 t
ORIGIN      
        1 attgctatta aaatttgtcg ttttaggtat aagtgccgta tttattttgt tcggcgtact
       61 tttttatact cagatcgcta caagcgaaaa aggattcaat tttgattggc agaccacatt
      121 atttgtttct gtcatttact ttgcccttct cctagggatc gttattgctt atttcttatt
      181 gaaactattg aaaaaaatcg aagataacca agctttttcc actcaaagct taaacatact
      241 aaaaaaaatc gaacgaacca ttttgtttat tggtttcgcc ttttttggct tacttcctaa
      301 atttatgaaa gtagcggatt tagacgatgc tccaggtttg atgttggtag gaatcgctgt
      361 cgtattcatt ccttttgcag tatacacatt aacaagcgtg ctggaaaaac tgcttgaaca
      421 tgcgatttta cttaagacag atcatgattt gacagtgtga ggtgcgacat ggcaattatc
      481 gttaatttag atgtagtatt agctcaaaaa aaaatgagtg tgactgaatt gagtgagaaa
      541 gtgggcatta cgatggcaaa catctctatt ctaaaaaatg gaaaagcaaa agccatccgt
      601 ttttccactc tcgaaaaaat ctgccaagtt ttggagtgtc aaccaggtga tttgttgacc
      661 tataaaaatg actcgaatac tataccagaa gaataaaata aagtagaaca aacagtaaat
      721 aaaaaataat ctgaatgata gatgtgtgag acttttagaa gttatttacg tctattattc
      781 agatttttta tttcgattga ataccgtttt atctataaat aagatatgta ctgactcata
      841 caaagggggc cttttcttct ccatgtacta tcacttttcc tgatacaact ggtttcctgt
      901 tacgttgtag ttggatctgc ttttagtata atactttatt cattccacca gactgatagc
      961 agtttgagca gtctaaataa tcatgtagta ttacaggcca ttctgtttca taccttgaag
     1021 tgcttaaaac ttcagctaat ggcccattgt gttaactctt actccattct tttttagtaa
     1081 gctcccatat atactgtaaa gccttctata tattatgtca tgttgctttt taacatttac
     1141 tatgtagttt tgataaaatg atttgaataa cagtgatgga caattctttt ttatttttaa
     1201 cattattttg ataataatg
//
LOCUS       DAFLWC010000213         1207 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.220, whole genome shotgun sequence.
ACCESSION   DAFLWC010000213 DAFLWC010000000
VERSION     DAFLWC010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1207
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.220"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            1098..>1207
                     /locus_tag="L1V17_002994"
     CDS             1098..>1207
                     /locus_tag="L1V17_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1237681.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELT"
BASE COUNT          429 a          202 c          188 g          388 t
ORIGIN      
        1 ctaattgtct cctttaattc atctataatt tcatccacga tattttaatc cgttctacaa
       61 tgcatatctg atatgcattg actgtctaac tcatatgtga atgatttata aaatatccca
      121 acgtctcatc taaagaaatg ttgatcgtca gcaaggagct aaaaaatacg aatatatttc
      181 ttttgtagta aaatcggact ggtttgcata tcattttctt cgtaaatatc aaaatcatgt
      241 taactactat caattactaa taaaaactac cactttaagc gttaagaact gttaagttta
      301 gttaagtgag gatagttcac aaaatccatt gttaaacttc acgaaagtgg taaaactcaa
      361 aatgctttat ataggattac agcatcgctc tttcttcgat tgcgcgttgg gtaaaaaata
      421 ttatgaagta aaaattgacg atgacacgtt ccttacggct catcagatga aacagctaca
      481 aaaacgaaat gatcaactcg aagaaaattt aattctaaaa aagcgattgc catattcacg
      541 cctcgctcga cgaactatta aaggtcaaga tttacctgaa gatcatcctt tttaggaaat
      601 tgaagctttt tatgttgcac aatgcattta taatactaca atgatgtttt caccagatat
      661 tcttctaggg tgcggtgtaa tgaaacagat acacttgcaa aagaaaattc accgcgaatt
      721 tactaaaatt atgaataatt atgttaatct tccgaaattt ttttccaaaa ttaagggatc
      781 aagctggtgt tatagattgt ttaaggttgg caaaaaaata acttcttttt aaacaattat
      841 agaaaaccga tactctgtta agttggttga cacggtgtcg atttttatga ctttcttatt
      901 ctgaaacttc actaacggac agtacctaaa aagtctatag tatggacgtt tacgagtact
      961 attttatcaa aaatgctgct catttcaact tatatgtttt agtgaactac ccccacttag
     1021 cttggatagg ctacaattaa ctagacagaa aaattaaggt gtgtagacta gaagaaaaca
     1081 taccaggagg aatttttatg tctaagagaa cacgaagaac tttttcacaa gaattcaagc
     1141 aacaaatcgt caatctttac ttagctggaa agccacgtgt agaaatcatt cgagaatatg
     1201 aactaac
//
LOCUS       DAFLWC010000214         1201 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.221, whole genome shotgun sequence.
ACCESSION   DAFLWC010000214 DAFLWC010000000
VERSION     DAFLWC010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1201
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.221"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(252..325)
                     /locus_tag="L1V17_002995"
     tRNA            complement(252..325)
                     /locus_tag="L1V17_002995"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(289..291),aa:Ile,seq:cat)
     gene            complement(880..1194)
                     /locus_tag="L1V17_002996"
     CDS             complement(880..1194)
                     /locus_tag="L1V17_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237682.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT          448 a          190 c          179 g          384 t
ORIGIN      
        1 tggtttttgg ggaacgcttt aaactcttct ttattattat ctcacaatat aacccaaatg
       61 tctttccatt taaaaatcaa agtaaaactt ttcaaatata cagaagtata actatgtgaa
      121 acatcctttc attaatccat aaaaggatac ataaaaaagc cactcatttg agtggcaatg
      181 aagaaaagct ttagcttgta taatactctt caaaaaattc taacacagaa cgattcaatt
      241 ggctacatta atgtaccctg taggactcga acctacgacc ggacggttat gagccgtctg
      301 ctctgaccaa ctgagctaag ggtagtggtt gttgccacat aaagccataa acaatcaacc
      361 agtagaatgc gtggcaacaa acctgttatc gcatatcttg gagtgtgact atttatgagt
      421 gatagtgaag atatgcgtct ccatatatgt atggttgaga cagataaaca tgtatgaaaa
      481 acgttgttaa atcaacgttt ttttattttg gtcaaggaga gaaaagtaga gaaatacaaa
      541 attttttgca ttgattttgc attcaaaaaa acattcaaac atttagaaat ccccaatacg
      601 tattcaggaa aatctatttt aaggtttaca aaaagaactt ttgttcgtac actctttttg
      661 aggtgaactt ttatgctgat ggaaggaaaa acacaattat ggtttaagca tgttccttca
      721 aataagtttt ttaattataa actctagaga aattaattca tcctaacata aaataattgt
      781 tcactcaaaa gtttttctag aacaattaaa acagcaggct tcacattcgc tatacatttg
      841 taagaagtaa taattcctgt actaaaaggc ataattgctt taattatttt ttgacttctc
      901 ttcaaacaca agaagtagtt gtgtaataat tgcagaaata aggattccaa taatagatat
      961 aaaatttgac atggaaacgt ctataacatt aaaagaataa agtgttgaag aaagtaaact
     1021 gattgaaata acccctccgt aaaaaatagt ctgtgaatat acccactttt tttcagaaga
     1081 cgtacttcgt ttggttctaa aacctatccc tgcatttcta ctcttatcaa aaaaccaaat
     1141 atttagaagt aataatattg ctattattaa gataaaatta ctgtaaaaat ccaaaagcta
     1201 t
//
LOCUS       DAFLWC010000215         1197 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.222, whole genome shotgun sequence.
ACCESSION   DAFLWC010000215 DAFLWC010000000
VERSION     DAFLWC010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1197
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.222"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..1101
                     /locus_tag="L1V17_002997"
     CDS             <1..1101
                     /locus_tag="L1V17_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBN1237683.1"
                     /translation="KKETIVRFEQYNHMPLVTRLKKQRYTCKNCRTHWTAQSYFVRLS
                     HSIADHVRYKIASLLTEKVSLSFIAKSCQVSLTTVTRTLKEFKSYLPKPSKKILPRVL
                     MVDEFRSHASIEDKMSFICADGETGNLIAVLPTRKLPRLTSYFLGCTNPEEVEFLVTD
                     MNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQALNELRIREMNELRKAGQKSQAEKLKK
                     NWRFLLKNRASINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSAPLKEAYPFFHELV
                     EAFRDKDPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITSAMIYPYSNGKIEAKNT
                     HIKTMKRVSYGFKSFENMRIRIFLINQLINVR"
BASE COUNT          394 a          244 c          223 g          336 t
ORIGIN      
        1 aagaaggaaa cgattgtccg ttttgaacaa tacaatcata tgcctttggt tacgcgccta
       61 aaaaagcaac gctatacctg taaaaactgt cgtacccatt ggacggctca aagttatttt
      121 gtccgactca gccattcaat cgcagatcat gttcgatata aaattgcttc tttactgact
      181 gaaaaagtat ctttgtcttt tattgcgaaa agttgtcagg tatctttgac taccgttact
      241 cgtacattga aagagtttaa aagctattta ccaaagcctt ctaagaagat tctccccaga
      301 gtattgatgg ttgatgaatt tcgttcgcac gcttccatag aagataaaat gagctttatt
      361 tgcgcagatg gtgaaacagg aaacttaatt gctgtcttgc ctacgcgtaa attacctcga
      421 ttaacaagct atttcttagg ctgcaccaat ccagaagaag tagaattctt agtcacagac
      481 atgaacgccg cttacttcca gcttaccaaa cgtgttctgc caaatgcgaa agtagtgatt
      541 gatcggtttc atattgtcaa acacatgaat caggcactca atgagttgcg tatccgtgaa
      601 atgaatgagc ttcgtaaagc aggacagaaa agtcaggcag aaaaactgaa aaagaactgg
      661 cgctttctgc taaaaaatcg tgcaagcatc aaccattatg agtacaaaac atggaaaagt
      721 ttccgagcac caaaataccc atttctcact gaagcaatga tgattgatcg attgcttgag
      781 ttttctgcgc ctctaaagga ggcgtatccc ttttttcatg aattagtcga agcctttcga
      841 gacaaagacc ctgacttatt tttctcctta ttggcagaac ttcccgaaac gttagatgac
      901 ggctttcggg agaagcttca aaaccttctg acctatgaag aaggtatcac cagcgcaatg
      961 atctatcctt attccaatgg aaaaattgaa gcgaagaata cccacataaa gacaatgaaa
     1021 cgagtatcct acggatttaa atcattcgag aacatgagaa ttagaatctt tttgatcaat
     1081 caattaatca atgtaagata acaaaaaatc tgaaccagaa tgtggttcat tctgacccgg
     1141 atttgatttt gcacaactca tcagtcctta ttgacaaaga gccaaaaatc tgagcca
//
LOCUS       DAFLWC010000216         1149 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.223, whole genome shotgun sequence.
ACCESSION   DAFLWC010000216 DAFLWC010000000
VERSION     DAFLWC010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1149
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.223"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            34..906
                     /locus_tag="L1V17_002998"
     CDS             34..906
                     /locus_tag="L1V17_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBN1237684.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT          333 a          220 c          279 g          317 t
ORIGIN      
        1 tgatttcatt ctaaaataaa gggagaaatg tctatgctat acggtgcaat tgaagcaggc
       61 ggcacaaaat ttgtgtgtgc cattggcgat gaagaaatga cgatcaagga aagagtgagc
      121 tttccgacaa cgacacctga ggaaacaatg cctttagtca ttgacttctt caaacaatac
      181 caagcagatt tagcagggat tgggattggc tcatttgggc ctatcgatat ccatcgcgat
      241 tccgccactt atgggtacat tacctcgacc ccgaaattgg catggcaaaa ttttgatttc
      301 atcggtacca tgaaaaaaga atttccgatc ccgatttctt ggacaacaga tgtcaatgcg
      361 gctgcctatg gtgagtatgt cttcggcagt ggcaaaggat tgagcagtgt cgtttactat
      421 acgatcggta cgggtgttgg cggcggtgcc ttacaagaag ggcgctttat cgaagggttt
      481 agtcatccag aaatggggca tatgctcgtc gtccctcatc caaaagatga ctttgctggc
      541 agctgtccat ttcatggcaa ctgtttagaa gggatggccg ctggacccgc catcgaaaac
      601 cgcttaggga aaaaaggaca agaggttgca gaagatgatc cttattggga aatcgaagcc
      661 tcctatattg ctcaatgtgc ctacaataca accttgatgt tttctccaga tgtgatcatt
      721 tttggcggtg gtgtgatgaa acaacgccat atgctgcaaa acgtccacga cgcatttgca
      781 aaattggtca atgggtatgt cgaaacacct gagttaagca aatatatcgt gaccccagca
      841 ttagaagaca acgctggaac gctcggttgt ttggcattgg ctcgagaagc ggtcttacat
      901 tcataaacga aaaaaggctc ttcgacattt agtgttggta gagaaagata caactgaaaa
      961 tttagtcata accagttagg cagagtgctt aactggtttt tgttttactt ggaagatcaa
     1021 gccttgaatg agataaattc ttgctcgaaa gttatggaaa tttcgatagc cgtaggccac
     1081 ttgtattgtg caatagtttt ttacaaaaaa aagggggtgc ggatattttt ttggaccttt
     1141 ttaacaaat
//
LOCUS       DAFLWC010000217         1136 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.224, whole genome shotgun sequence.
ACCESSION   DAFLWC010000217 DAFLWC010000000
VERSION     DAFLWC010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1136
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.224"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            290..1135
                     /locus_tag="L1V17_002999"
     CDS             290..1135
                     /locus_tag="L1V17_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1237685.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
BASE COUNT          424 a          134 c          188 g          390 t
ORIGIN      
        1 tttaaatctt ttgctaagtt gaactaatag agtcttttat gaatatcgaa gttagttttt
       61 cacctaactt cgttttttat agttggttat tataaaatag taatatagct gatttggatt
      121 caattcatat ttatttataa atcaaaaata cagagaatag tatataaatg tcctttccta
      181 ttcttaaaat gatgtttgta cttacttaaa ttaggtataa ttagtatatg ttttgtgaga
      241 aatttagact tacaataagc agtgaattta taatcaacgt ataggagaca tggatgaaat
      301 gaaactaatt ggtatagatt tagacggtac tcttttgaat tctgaccaga gcattagtca
      361 aaaaaatgca agaacaatga aacatttacc ggaagactgt tttccattca tttgttctgg
      421 aagagaagta gaagacatta ataatattct caaaaaatct ggtttaagga taccagcagt
      481 agggttaaat ggttctgttg gatttgatgg agaaaaaaag atatttgagt cttccttcga
      541 taaaaatgat gtaaaaaaaa ttgattctgt cctatcgaaa tttccaacca aaatatatac
      601 aaatctcgga agttatgaat ctcagaatta taaaaataaa atgaaaaaaa tttttcacga
      661 ggtagggagt gaattttcta tcaaagagct aaactatgag cttgagtatg aaaaatctat
      721 ttgttcaatc ccttataata atattgagga aattatagaa aaggatgcta tcagcattta
      781 caaatttttt atttttattc ctaatcgtca attgaaagct aatatattta accatttgaa
      841 aaagatgcta aatgtgtctg ttactgaatc ggcacctgta aatattgaaa tcgtacctca
      901 aaatgtatct aaaggtgtgg tgtttgatcg tttggaatca atctacaatt taaagaaacc
      961 tttgagaatc gcgatcggag atagtttaaa tgacttatct atgtttgaaa gtgcagatat
     1021 tagttttgca atgggaaata gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt
     1081 ttcaaatgat aaagacggag tatctcaagc atttgaaaga attcttacca tataaa
//
LOCUS       DAFLWC010000218         1069 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.225, whole genome shotgun sequence.
ACCESSION   DAFLWC010000218 DAFLWC010000000
VERSION     DAFLWC010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1069
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.225"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..969
                     /locus_tag="L1V17_003000"
     CDS             <1..969
                     /locus_tag="L1V17_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBN1237686.1"
                     /translation="PINTFAYTINDEYNLAPNQGDSRLAIPNKIILHETGIDAPARNV
                     AANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAGNANPYAPVQIELQRTYDKA
                     LFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIISHLWVTNYVWGNHTDPYGYL
                     SQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNHAHIDQFGE
                     IENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTSGNVGYH
                     VSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
BASE COUNT          368 a          185 c          214 g          302 t
ORIGIN      
        1 cccattaata cgtttgctta tactattaat gacgagtata atttagcgcc gaatcaagga
       61 gactccagat tagcaattcc taacaaaatt attttgcacg aaactggaat agatgcacca
      121 gcaagaaacg tagccgccaa catgaaaaat aattataacg gaagcaattc ttatactaca
      181 gatgttattg gtgacggtgg gattgtttac cgtgtgggtg agcaaggata tgtttcgtgg
      241 ggagctggta acgctaatcc ttatgcgcct gtacagattg aattacagcg cacatatgat
      301 aaagcattgt ttgaaaaaaa ctatcgagct tatattgaat atacaagaga tagtgcaaaa
      361 aaatatggaa ttccattgac tcttgatcaa ggaacttctt tatttacaaa aggaatcatt
      421 tctcatttgt gggtgacaaa ttatgtttgg gggaaccaca cagatccata tggttactta
      481 tcgcaaatgg gagttagcaa agaaaagctt gcttatgatt tagctcatgg atttaccgat
      541 gaaaatccaa caacttctga aaacaagcct gtcattgatc caacacgagc tggtgcagct
      601 aatcctacgc tgacagatgg aacaaatcac gcccacattg atcagtttgg ggaaatcgaa
      661 aacgcaaact tgcatgtggc tggatggcac attgctaact ataaatacga gtatattttc
      721 attatggact acaatactgg gaaagaatta gctcgagtaa gagctgatgg aatttataga
      781 ccagatgtaa accaagctta taatacttct ggaaatgttg gttatcatgt atctttcaat
      841 atgcgtaatt ttcctagtaa gaaagtctat gtaatgatgc gggcaacgaa tgatccagag
      901 ggaaacacta aaggcggtgc gcaagatttc catgacaaac gttggtattt aaatattcct
      961 aaacgataaa aatagctcct cgttgaggag cagtacataa ctatattgac aactataaaa
     1021 attattcgat aaaatagtga tgttatcgca tatcttcact atcacccat
//
LOCUS       DAFLWC010000219         1066 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.226, whole genome shotgun sequence.
ACCESSION   DAFLWC010000219 DAFLWC010000000
VERSION     DAFLWC010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1066
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.226"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(35..844)
                     /locus_tag="L1V17_003001"
     CDS             complement(35..844)
                     /locus_tag="L1V17_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBN1237687.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT          323 a          202 c          187 g          354 t
ORIGIN      
        1 tcacaacctc ttttttgtgg aatctaattc tctattatag tttaagtagt ttttccagat
       61 aaacagctaa accgtcttcc tgattgctca aaggagtgac atcatttgca atgcctttga
      121 gttggtcagt accgttagcc atagctactc cccaacctgc ataatccaac aattccaaat
      181 cattatgctc gtcaccaaag gcaatgacgt ctttttgatc gatagacagg tagttagcaa
      241 tctcttgcac gccttttgct ttttggattc cttttgaaac aatctctaag atggcagtag
      301 gtccacccca tgtccgaaca tcgacataac tgccaaattg acgtgttaat tcagcagata
      361 cagctcctgc aaaacgtttg tctgttcgga caagcaaaga tgtaggattt gtcgtcaaat
      421 ttttaggaga aagcaaattc ttctctcctg gacgagaaga agcaaaaatt ttttcatcaa
      481 agaaatcaaa actgtcaata aaaaaagtat cacgattttc agcagcgata aaatctaaat
      541 ttagctgctt tttttgcgat aagatttcaa aagcgatttc acgattgatc aacgtttctc
      601 tttcaccatc ccagtgctga ttagggatgt gtactaatgc gccgttaaaa ttaaccatcg
      661 gtgttgttaa ttctaattgt tggtaaaact gatggctcat tcggaatggg cgtcctgtag
      721 caatactgac atgatgaccg gcattgattg ctttttttag agtctctttt gttttagatg
      781 taatcatcga atcttgattg agggtagttc cgtccagatc gatggcaatt aattttttat
      841 tcaataaggg tccttccttc ctcaactagc atttgtttta gtctagcata ttttaggtaa
      901 ttaacaagag caatcagcta ttcctaacaa aaactacagt tatggctata taaatagcta
      961 aacataagct aaacacgaac gttaagtatt attttcgctt tttttgttaa aaaaacgttg
     1021 aaaagcgaat gaaacgtcta tataatttga aattgttcga tggatt
//
LOCUS       DAFLWC010000220         1063 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.227, whole genome shotgun sequence.
ACCESSION   DAFLWC010000220 DAFLWC010000000
VERSION     DAFLWC010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1063
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.227"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            1..611
                     /locus_tag="L1V17_003002"
                     /pseudo
     CDS             1..611
                     /locus_tag="L1V17_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177099.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            669..>1063
                     /locus_tag="L1V17_003003"
     CDS             669..>1063
                     /locus_tag="L1V17_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237688.1"
                     /translation="MIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDSELLSFGIG
                     LTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLNIIQAPWRF
                     MIFSTLFISFSVSLFISPQLEKFSYTRRR"
BASE COUNT          335 a          150 c          144 g          434 t
ORIGIN      
        1 tttatgcatt tgttagttta ttatatttat ttccagcatt taaaaacatg gaaatatttg
       61 gcttttatga tacggcattt cacattaatc gtgcgttaag tttagaatct atttttagct
      121 cccctattaa ttttgaaacg tttagatcat atggcatgca agtaaataat ttttacccat
      181 ggttaactct atatccttta tttttattga tcaagtttac taatttagca ataggctata
      241 acctttttct ttatattgtt acgctcatta ctctatttat atgtcattat gtaatgtatg
      301 aaattaccaa aaaacatgtt actagctcct ttttcgctat tatatataca acatcttctt
      361 ttaggagtgt agaaatattt cttcgagggg caatggggga attactcgca atgtcaatac
      421 ttcctcttat tttactcggg tttataaagc tttacgactc aaaaaaagaa tcttgggtta
      481 tgttggcgat tagcatgact ttattaattt acactcatgt tctttctgta gctatgacta
      541 tggtaatgat tataattgct ttaattattc aattttatcg gaaaaagaaa atagaaatct
      601 tcttaattat taaattaata aaagctgcta tagttacttt acttctttca ctagcgttta
      661 taggtcctat gattgagcag acattgtatc aagatctgaa tagaccttat gtggatatat
      721 tacaaaaaag agcaatttat ctgggtaaag agtttttgat tggaagtata gattcagaat
      781 tactatcatt tggtattggc ttaactttgc ttatttgttt aattatacta acatttaact
      841 ttaaaaaatt aggaatctta tctaaaatca cttatataat gggtataata tctattctac
      901 tttgtacaaa aatatttcca tggtttgcct tacaaaatac tcctttaaat attattcaag
      961 ctccttggcg ttttatgata ttttcaacat tgttcatatc tttttcagta tctctattta
     1021 tttctccaca gttggaaaaa ttttcttata caaggagaag aaa
//
LOCUS       DAFLWC010000221         1060 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.228, whole genome shotgun sequence.
ACCESSION   DAFLWC010000221 DAFLWC010000000
VERSION     DAFLWC010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1060
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.228"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(38..994)
                     /locus_tag="L1V17_003004"
     CDS             complement(38..994)
                     /locus_tag="L1V17_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237689.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          344 a          176 c          160 g          380 t
ORIGIN      
        1 tttagaaaaa gcagtcggac tttctaaaag aagttcacta ttcgatcctg tcgatgattt
       61 cttcaggaaa atcgtctatt tgcttgtcaa ttttgctgtc tttgtatttc tcttcttgga
      121 tagtcaacaa aatctttgta agattccccc agtctactgc tcttggcgga tcgagccaaa
      181 ccactacttg agatgcactt tcttcatata gattattcct attcgtgatt ataacatccg
      241 ggaactcagg ctttcctgcc tctatcactt ccgtgttcag attaatgtac aagcttaaat
      301 ttttcttgat aaattgatta taggcagcac cataagaaaa atcgatgatg atctttactg
      361 gttcagaaat cagttgaatg ggtatgtgat tgatcaataa taataaataa ctgaaaaaaa
      421 gaaaaaattt atcttgaagc aactctttgc gttttgacgt tagatcattt atatactcta
      481 tcaaatagca ataaaatgct ggatagtttt ctctaaaaaa agaaacatca agtggaaatt
      541 catcagcttt attaatagtg taatgcaaaa gtttaaaatg tattttggtt aactctcttc
      601 ggatcaattg gctcgtctct tctcgcaaca gattaaactg attttcaaaa ctttcaatga
      661 atcgttcatt caaccattcg attgtttcat cttcattttt tctcaagtat ttttgatcca
      721 atttatcatg aagataaagc caagagagtg tcttattgat aaaaataacg gatttttctc
      781 ctaatactcc ttttaagtgg taaaatccta tatccgaaaa aaatagcgac tgattgctag
      841 caatatctaa agaatcagct tgttcagcca acaggttgat tgctaaaaag tggaataatt
      901 tctttttttc ataagcagac agaggataat actgttttaa atcttttaac attttttctg
      961 tttttataat tataggtagc gtatacaatt ccacaaaact tatctctgtt gagttaaaaa
     1021 gattatataa aaaaagccga atgtttttag gattccctgt
//
LOCUS       DAFLWC010000222         1054 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.229, whole genome shotgun sequence.
ACCESSION   DAFLWC010000222 DAFLWC010000000
VERSION     DAFLWC010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1054
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.229"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            143..400
                     /locus_tag="L1V17_003005"
     CDS             143..400
                     /locus_tag="L1V17_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237690.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(632..1048)
                     /locus_tag="L1V17_003006"
     CDS             complement(632..1048)
                     /locus_tag="L1V17_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HBN1237691.1"
                     /translation="MMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVLSASIP
                     ILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEKLLYIT
                     KTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          394 a          135 c          140 g          385 t
ORIGIN      
        1 ttttctgtcc acgttcattt tactccaaag ttttcctcat ttcaaaagaa aatcacagaa
       61 tacacgaaga agcgtttcta tttgtataaa ctatatcaaa gttctatact taaattatca
      121 aataaaaagg acgtgaagat aaatgtcaaa tttagaaaac aaagaagaaa aagttgtaaa
      181 caaaattgtt tctgttgtca ataaactgga taaagagtta gacgaacttg atacgttatc
      241 tgaaaatcca gaaaaaaaac ataacctaaa aaaatggtta gttgaacgaa aggctattca
      301 tgaaattaaa aaagttcttc atgaagctga taaatatgaa aaatatgatg aaaaagaact
      361 tgataaagaa tttaaagaaa tcaatgactt attactataa ttgatttata cgactcattt
      421 ttgagtcgtc agactgcaaa caacactcta aatttaggag tttgtctaca gtctgaatag
      481 attttaaatt tattgtccat aatgttatta tgaatttata gcattaagaa aagagataag
      541 actttacatt tttttaggaa tgtaaagtct tatctctttt cttaattgta caattagtat
      601 tatctgcact actttctaat taaataaatt tttagttatt aacttgatta aaatcagaga
      661 taatatcatt taattcagtt tgaagggttg taacgattaa atggaaattt tcttcatctg
      721 ttttattata tggggatgtt ttcgttatat ataacaactt ttctttttca attttcatta
      781 ataactctgt cgaagtctgt actttatctt gataattaaa tgcagacata ccactttgta
      841 taattgtaat tattgctgaa gcaattgaaa caatcaatag taaagacctg tgttcggaag
      901 cctgatcaat taatattggg atactagctg ataagactat ttttataata tttccgatac
      961 caattactct attataaaat cgaatttctt tttttaatct atcgattgta gaatcaatag
     1021 attcgataaa cgctttttga tccatcattt tctc
//
LOCUS       DAFLWC010000223         1045 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.230, whole genome shotgun sequence.
ACCESSION   DAFLWC010000223 DAFLWC010000000
VERSION     DAFLWC010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1045
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.230"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="L1V17_003007"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="L1V17_003007"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HBN1237692.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          376 a          132 c          182 g          355 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaagct aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgacga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgtaggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaac
//
LOCUS       DAFLWC010000224         1035 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.231, whole genome shotgun sequence.
ACCESSION   DAFLWC010000224 DAFLWC010000000
VERSION     DAFLWC010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.231"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..>1035)
                     /locus_tag="L1V17_003008"
     rRNA            complement(<1..>1035)
                     /locus_tag="L1V17_003008"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          218 a          324 c          234 g          259 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatgcaccgc gggtccatcc atcagcgaca
     1021 cccgaaagcg ccttt
//
LOCUS       DAFLWC010000225         1021 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.232, whole genome shotgun sequence.
ACCESSION   DAFLWC010000225 DAFLWC010000000
VERSION     DAFLWC010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1021
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.232"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            4..684
                     /locus_tag="L1V17_003009"
     CDS             4..684
                     /locus_tag="L1V17_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBN1237693.1"
                     /translation="MIINAGVIIGLMLVIFSGKQYADNILLWGGEDNIEKINNNLTIL
                     DTALENKEQKISILNSQLSSNNQTLEQLRTNIEVSKQKVASLENDKNQLVSEKTNLEN
                     QLSAKDSELQGKQNEINAKIDEINQKVAEINRLNSDWNNRLQNEKNKFNEEQSTINSL
                     NQQINQMLSEKNNIQNQLQATQQKLEEEKSKNSSLNNYIEKLQKAKNDVEDTANKAQQ
                     IVNEHTIQ"
BASE COUNT          448 a          118 c          150 g          305 t
ORIGIN      
        1 aagattatta ttaatgctgg agtaattata ggattgatgt tagtaatttt ctccggaaag
       61 caatatgctg ataatatttt attatgggga ggggaagata atattgaaaa gatcaacaac
      121 aatttaacta tattagacac agctctagaa aataaagagc aaaaaattag tattttaaat
      181 tcacaattgt cttcaaacaa ccaaactctt gaacaactaa gaactaatat tgaagtttcc
      241 aaacaaaaag tggcatcttt agaaaacgac aagaatcaat tagtatcaga gaaaactaat
      301 ttagaaaatc aattgtcagc aaaagactct gaattgcaag gaaaacaaaa tgaaattaat
      361 gcgaaaatag acgaaattaa ccaaaaagta gctgaaataa atcgattaaa tagcgattgg
      421 aataatcgtt tacaaaatga aaagaacaaa tttaatgaag aacaatctac tattaatagt
      481 ttaaaccagc aaattaatca aatgttgagt gaaaaaaata acattcaaaa tcaactgcaa
      541 gctactcagc aaaagctaga agaagaaaag tcaaaaaata gtagtttgaa taattacatt
      601 gaaaagcttc aaaaagctaa aaatgatgta gaggataccg caaataaagc acaacaaatt
      661 gtaaatgaac atacaatcca atagatatag ttttaattta acaaatggta tgtttggaga
      721 taatgagata gaatataaat gtcataatat tatacaatct aaacaccgtt tccttttcta
      781 tttttgatga catcagtata tagctactcg aaagagtagt ctttttatta ttctcgctta
      841 ttattgatat gaaaatttcg atttgacaaa aggtaccgaa taattttgta atatgaatta
      901 ttatcaagaa gtaattatga tgataacata tggaaactag ttagtaataa taacaggtga
      961 ttaaactttt gaacgacttg taattctata ttttttcttt taagtaaaaa atataggtga
     1021 t
//
LOCUS       DAFLWC010000226         1003 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.233, whole genome shotgun sequence.
ACCESSION   DAFLWC010000226 DAFLWC010000000
VERSION     DAFLWC010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.233"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            370..1003
                     /locus_tag="L1V17_003010"
                     /pseudo
     CDS             370..1003
                     /locus_tag="L1V17_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          182 c          184 g          295 t
ORIGIN      
        1 gtttcaaagt tagtagagaa aatgtagtta tatatttaaa tttttaccag aaagaaatga
       61 acaccttcaa ttatctaaat ctcgaaaatg gttagatgta atcatcagga aaaacaatct
      121 taaacgaatt actattcatg gtcttagaca cacacatgct agcttgcttt tagcaagcta
      181 gtgcaaatat taaagatgtg caagagcgtt taggccactc ttctattcaa atcattatgg
      241 atctatatat tcatattaca gacaaaagaa aagaagaaac cgtagcgcaa ttcgcaaaat
      301 ataggctcta taatttatgg gactgatgaa tcaaaattga ttcttcagtc ccattgttat
      361 tttaggtata tgattcgtac attgaaagag ttgaaaaact atcttccgaa gccgtcaaaa
      421 aggaccctgc caaaagtatt gatggtggat gaatttcgtt cgcacgcttc aattgtggat
      481 aaaatgagct ttatttgtgc ggatggcgag actggaaaac tcattgatat tttgcctaca
      541 cgaaaattgt ctcgattaac acactatttt agtcgctgtg caaatcctga agcggtggaa
      601 tatttagtga cagatatgaa cgccgcctac ttccaactga caaaacgtgt cttaccaaat
      661 gcgaaagtcg tcattgattg ttttcatatc atcaaacatt tgaatcaggc gttcaatgat
      721 tttcgtgtac aagaaatgaa aagattacac cagttagggc aacgacggga agccgagaaa
      781 gtgaaaaaga actggcgctt tcttctaaaa aaccgtcaaa aaatcaatca ctatgattac
      841 aaaacatggc gcagttttcg tgcacctaaa tacccgctac tcactgaagc aatgatgatt
      901 gatcgattgc tggcattttc aacgccttta aaggacgcct atactttttt ccatgagctg
      961 accgaagcct ttagagacaa ggaatcagac ttatttttta cct
//
LOCUS       DAFLWC010000227          986 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.234, whole genome shotgun sequence.
ACCESSION   DAFLWC010000227 DAFLWC010000000
VERSION     DAFLWC010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..986
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.234"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..>986
                     /locus_tag="L1V17_003011"
     CDS             <1..>986
                     /locus_tag="L1V17_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBN1237694.1"
                     /translation="LEPGDFIMSGAGTIGRISRVPKQIKPGVFNQALIRLRINKEITD
                     SEYFIQFIRADFMQRKLTGANPGSAITNLVPMSEVKKWIVQFPILEEQKKIGNFFKQL
                     DDTIALQQRKLDLLKETKKGFLQKMFPKNGAKVPEIRFPGFTEDWEQRKFKEFSKKTG
                     KKNTKDLDFPAYSVSNKAGLISQTEQFDGSRLDDLEKTNYKFVEPNEFAYNPARVNVG
                     SIAFNNLGMTVIVSSLYVVVKMSEDLDNEFILQFIKSPTFIKEVKRNTEGSVREYLFY
                     ENFANIKFPFTRNKEEQQKIGAFFKQLDDTIALHQRKLDLLKETKKGFLQKM"
BASE COUNT          375 a          159 c          189 g          263 t
ORIGIN      
        1 ttagaaccag gcgattttat catgagtggc gctggaacaa ttgggagaat ttcaagagta
       61 ccaaagcaaa taaaaccggg tgtattcaat caggctttga ttagacttag aataaataaa
      121 gaaatcacag attcagaata ttttattcaa tttattcgtg cagattttat gcaaagaaaa
      181 ctcacaggag ctaatccagg ttcagcaatt acaaatctcg taccaatgtc agaagtgaaa
      241 aaatggatag tacaatttcc aatattagaa gaacaaaaga aaattgggaa cttcttcaaa
      301 caactggacg acactatcgc tcttcaacaa cgtaagctag atttattaaa ggaaacgaaa
      361 aaaggattct tacaaaaaat gttccctaaa aacggagcaa aagtgccaga aattcggttt
      421 cctggattta cggaagattg ggaacagcgt aagttcaaag agtttagtaa gaagactgga
      481 aaaaagaaca cgaaagattt agacttccct gcctattcgg taagtaataa agcaggttta
      541 atttctcaaa cagaacagtt tgatggtagt aggttggatg atttagaaaa aacaaattat
      601 aaattcgttg aaccaaatga attcgcctat aatccagcaa gagtaaacgt aggatcaatt
      661 gcatttaaca atcttggtat gacggtcatt gttagctctc tttatgtagt tgtgaaaatg
      721 agcgaggact tagataatga gttcatactt cagtttatca agtcaccaac atttatcaaa
      781 gaggtcaagc gcaacactga aggaagcgta cgagaatact tattctatga gaatttcgct
      841 aatatcaagt ttccttttac taggaataaa gaggaacaac aaaaaatcgg cgctttcttc
      901 aaacaactcg acgacacgat cgctcttcat caacgtaagt tagatttgct gaaggaaacg
      961 aaaaaaggct tcttacaaaa gatgtt
//
LOCUS       DAFLWC010000228          972 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.235, whole genome shotgun sequence.
ACCESSION   DAFLWC010000228 DAFLWC010000000
VERSION     DAFLWC010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..972
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.235"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            100..>972
                     /locus_tag="L1V17_003012"
     CDS             100..>972
                     /locus_tag="L1V17_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBN1237695.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDEFFIQSAASKRNN"
BASE COUNT          340 a          169 c          179 g          284 t
ORIGIN      
        1 ttattacgcc gattgtaaaa ttaagctaga caactaaaaa agtcatttgt gctacactca
       61 aaatagttcc gaccaaagaa ttataaggag tgagtacaaa tgacctatac ccatcttaca
      121 acggatgaac ttgtaataat agagtcttat ttcaaaatga atcaatctgt tgctaaaact
      181 gcccattgct tgaatcgttc aagacaaacg atccataaag tatatctgtt cttcaagcaa
      241 ggaaaatcag ccttagaata ttatcaacag tataagaaaa acaaatcaaa ctgtggtaga
      301 cgtccgcttg ttttacccga ggaacaatca gaatatattc aaagaaaggt tgttcaagga
      361 tggacacccg atgtgattgt tggtcgtgca gcgtttccta ttagttgttc tgctcgtacc
      421 atttatcgta tgttcaaaaa ggggctattt gattcttctg acttaccgat gaaaggcaag
      481 cgtaaaccga atggacatca agaaagacgt ggaaaacaaa ctttccgccg ctctattcat
      541 gaacgtgaaa aggattatag ccaattctca aatgagtttg gtcaccttga aggtgacact
      601 atcgtaggtc tgaaacataa aagtgctgta attaccttag ttgaacgatt atcaaaagtt
      661 atcatcacat tgaaaccgtg tggtagacaa gcgattgata ttgaaaaaaa attaaatcaa
      721 tggtttgaat ctgtaccgaa aaacctattc aaatccatca cttttgattg tggaaaggaa
      781 ttttcaaatt ggaaacagat cagtaatgtc aatgatattg ccatttattt cgctgatcca
      841 ggaacgccgt ctcaaagagg cctaaacgag aattctaacg gattgttacg tagagatggt
      901 ttattgaaat ctatggattt caattcagta gatgaatttt ttattcaatc tgccgcatct
      961 aaacgaaata at
//
LOCUS       DAFLWC010000229          959 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.236, whole genome shotgun sequence.
ACCESSION   DAFLWC010000229 DAFLWC010000000
VERSION     DAFLWC010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.236"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(107..511)
                     /locus_tag="L1V17_003013"
                     /pseudo
     CDS             complement(107..511)
                     /locus_tag="L1V17_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
     gene            complement(570..>959)
                     /locus_tag="L1V17_003014"
     CDS             complement(570..>959)
                     /locus_tag="L1V17_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1237696.1"
                     /translation="KDRKEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSL
                     IENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFD
                     TYNQKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          287 a          170 c          159 g          343 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgagacacg acctaaagat cgtgtctaat
       61 tatgactgta tcagaaaata tgataccaaa cggatctatt cattaattaa ttgacatagt
      121 ttatctgttg ctcttttatg actggataac tgaccaattc atgacgatcc aagtcttctt
      181 tattcatatt tacagcagta atttgactgt cttcatacgt acgataataa taaatccctt
      241 tatcaacgtt acagcaagaa gaataaatcg tatattcgta ttttccttct ccagtatcgc
      301 atactccttt ttgttgctcg actgagccta gtatatgaaa aaattgactg atactttcag
      361 attctgaatc acctgatgca gcattcattt tagtaaatgt ggcttttaca aatcgagaaa
      421 cagaagagag atctccaggt aagcccaatc ctcccatccc acgactataa acattcaagc
      481 tgatctggtt tgaaaaatga ttttctggtg ttccattggg agcgtcaata attttgtgta
      541 aataaattgt cctcctgcaa aataattagt tactcagtaa acattgaaac taatgtatcg
      601 gttacctgtt gaaaaccttt atggcttctg tttagaaatt tttgattgta tgtatcaaaa
      661 atgctgacta gaaagcgttc tagtgattct tcattttgaa actgctcttt tctacggctg
      721 tatcttttaa tttgcttatt gaaagactcg attagattgg ttgagtaaat ggttctacga
      781 atgctaggtg gaaaatcata aaaagttaat aagtcttggt tttctatgag tgactgcgtc
      841 actttaggat agtttttctt ccatttctca atcatgccgg ataagaaggt attcgcttct
      901 tcttttgagt tagcttgata aacagcctta aagtcatcac agatttcttt tcggtcttt
//
LOCUS       DAFLWC010000230          955 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.237, whole genome shotgun sequence.
ACCESSION   DAFLWC010000230 DAFLWC010000000
VERSION     DAFLWC010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..955
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.237"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            57..749
                     /locus_tag="L1V17_003015"
     CDS             57..749
                     /locus_tag="L1V17_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBN1237697.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSWKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT          415 a          143 c          163 g          234 t
ORIGIN      
        1 tgtttgagat cacttacttt tagcatgtaa aagtattgga ttaaggagct atgcaaatga
       61 aaaagaaatt tattactggt gggattgtcg ttgcatttct atgtctaatt ggctacacag
      121 gcacgcggta cgcaaatgaa attattttgt ggggtggaga gacagatatt gatacaatca
      181 atgagaatct gacacagctt gatcatacat tgacagataa agagcaagcg attacagatc
      241 ttaccgctcg actagcacaa aaagaacaga cattgcaaga ttcaaaggca gatgtccaag
      301 aataccaaac aaaagtaaat gaattagaaa accaaaaaaa tcaatcggca gcagaaaaac
      361 aaaacttaga aagtcaatta gtcagcaagg atgcacaact acaaagcaaa caaaatgaaa
      421 tcaatgtcaa actagatgag atcaaccaaa aaaatgatga aatcaatcat ctgaatgcag
      481 attggacagc aagactacaa gaagcacaag caaaactttc agaattacaa aatactgtaa
      541 atggtttgaa tcaacaaatc gcaacactga cacaagaaaa aacaaatgta gaaactcagt
      601 taacagatac acaaaagaaa ttagacgaag caactgctga aaactcaagc tggaaacaat
      661 atattcaaaa gttagaaaaa gcaaaagatg aagtggaaga tacagctgat aaatctcagc
      721 aaattgttga agaacatttg cgtaaataat ctttcttaac aagtaaacct aaattagtaa
      781 agaagcaaca gtaatctata ctaagtagtt cagttttgga gtacaaaatg acaaaatgta
      841 cttcaaaatg gactactttt ttcattttaa cttacatacc aaattacata caaaatgatt
      901 tataaaatgc aattgaaaat gataattgaa tgaaaatttg tgattttgtg gtatt
//
LOCUS       DAFLWC010000231          943 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.238, whole genome shotgun sequence.
ACCESSION   DAFLWC010000231 DAFLWC010000000
VERSION     DAFLWC010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.238"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..>943
                     /locus_tag="L1V17_003016"
     rRNA            <1..>943
                     /locus_tag="L1V17_003016"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          293 a          187 c          274 g          189 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact agg
//
LOCUS       DAFLWC010000232          858 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.239, whole genome shotgun sequence.
ACCESSION   DAFLWC010000232 DAFLWC010000000
VERSION     DAFLWC010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..858
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.239"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..117
                     /locus_tag="L1V17_003017"
     CDS             <1..117
                     /locus_tag="L1V17_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBN1237698.1"
                     /translation="KKILIIDDVYTTGQTLFHAADCLQNAQPKIIRTISLAR"
     gene            245..796
                     /gene="raiA"
                     /locus_tag="L1V17_003018"
     CDS             245..796
                     /gene="raiA"
                     /locus_tag="L1V17_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBN1237699.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
BASE COUNT          307 a          151 c          177 g          223 t
ORIGIN      
        1 aaaaaaatat tgattattga cgatgtctat acaacaggac agacgctttt tcatgcagca
       61 gattgcttgc agaacgcaca gccgaaaatc atccgaacca tttctttggc aagatgaatc
      121 agatgtggaa atttgatagc gatttaattt gcaaataacc tagagttcga tataatagaa
      181 ttaagaagag ggaaagagtg gtccttctcc ttcttgattg tggtagacga aaggggtaat
      241 ttttatgttt agatataatg tacgcggcga aaatatcgaa gtaactgaag cgattcgcga
      301 ctacgttgag aaaaaagtag gcaaactaga acgctatttc agtgacgcac ccgatgcaac
      361 ggcgcatgtg aacttaaaag tttatacaga aaaaacagca aaagtggaag taacgatccc
      421 attaccttat cttgtattac gtgccgaaga aacttctcca gatttatacg caagtatcga
      481 tttggttgtt gacaaattgg aacgccaaat ccgcaaattc aaaacaaaaa ttaatcgtaa
      541 atcccgtgaa acgggcatga atactgcaga tgctgctgct ttattcaatg aagaggacga
      601 aaacgaaaat gattctgaat tagatatcgt acgtacgaaa cgcctttcat tgaaaccaat
      661 ggatagtgaa gaagcagtct tacaaatgaa catgctggga cataacttct ttatttttga
      721 agatgcagaa acaaatggta caagtatcgt ttaccgccgt aaagatggaa aatacggact
      781 gattgaaaca gactgatcag ccttacttaa ataacaacga aaacttgcag cagctactga
      841 cagctgccgc aagttttt
//
LOCUS       DAFLWC010000233          842 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.240, whole genome shotgun sequence.
ACCESSION   DAFLWC010000233 DAFLWC010000000
VERSION     DAFLWC010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..842
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.240"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..>842
                     /locus_tag="L1V17_003019"
     CDS             <1..>842
                     /locus_tag="L1V17_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HBN1237700.1"
                     /translation="RNLDSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYY
                     WVKKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMG
                     LTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPIL
                     DLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLK
                     ENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKR
                     IKLK"
BASE COUNT          367 a          108 c          136 g          231 t
ORIGIN      
        1 agaaaccttg attcaagaac aagatttgag caagaagaaa tcaaggttaa aacaatcctt
       61 cagctcaaaa aagaatttaa attgaatcta ttactttcaa ttgcacaatt agcgaagtca
      121 acttattatt actgggtaaa aaaattagat aagccagata aatatagcaa gataaagcaa
      181 gaaattacag cgattgtaaa agaatcaaga aactcttatg gttatcgtag agtcacttta
      241 gcgttaaaga tgaaaggata tacaatcaat cataaaacag ttagaaaatt aatgtcccaa
      301 atgggactta cctgtcaaat ccgaataaag cgatataaat cttataaagg aacagtagga
      361 aaaattgcca agaatgtgtt aaaacgaaat ttttcagtag atacacccaa taaaaaatgg
      421 gtgacagacg tcactgaatt caagataaaa ggaagaaaaa tctatctatc tcctatactt
      481 gatttattta acggagaaat aattagttat agtatatcaa ctagtccaac atataaactg
      541 attgaagaaa tgcttcaaca agcaattaaa aaaaagggaa ctgagggttc actgattcta
      601 cattcagatc aaggatggca gtatcagatg ccacaatatc aaaaaaaatt aaaagagaat
      661 aacattattc aaagcatgtc tagaaaagga aattgcttag ataattctgt aatagaaaat
      721 ttttttggtg tgcttaaatc agagtttttt tatcgagaaa aattccgatc aattgagata
      781 tttcaaagta aattaaatga gtatattagg tggtataata acaaaaggat aaaactaaag
      841 tt
//
LOCUS       DAFLWC010000234          825 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.241, whole genome shotgun sequence.
ACCESSION   DAFLWC010000234 DAFLWC010000000
VERSION     DAFLWC010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 825)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 825)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..825
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.241"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            159..>825
                     /locus_tag="L1V17_003020"
     CDS             159..>825
                     /locus_tag="L1V17_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBN1237701.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKN"
BASE COUNT          317 a          123 c          125 g          260 t
ORIGIN      
        1 tactccttct ttttggactg attttatcga aacttatttt ttcttttttt catgtattct
       61 tttattttta taactagtgt attacttcaa aatttgatat tatatggcat gaacagaatt
      121 aaaatatcag ttaaaataaa agttaaggag cattgtgtat gacaattaaa actagtctcc
      181 aaaatcaagc ttaccaatct attcgccgac aaattatcta tgctgactta gaacctggaa
      241 aaaaagtatc agaaaaaaaa ttagaagaaa cactttctat tggtcgtaca ccaatacgtg
      301 aagcactgat tcaactccga caacaaggtc ttgttgatac aattcctcaa agcggaaatt
      361 atatctcatt aattgattta gattcggcca aaaatgctcg atttgtcaga gaacatttgg
      421 aacgacaaat tatgttagag tgttgtgcca aaatgaataa ccaaaaaaaa cggattttag
      481 aaactataat ttcagaacaa gaaaaagctg ttagtcaaaa aaatgctcgt agtttttttc
      541 ataatgataa tttattccat aaagcttgtt ttgaaattgc agagcgagaa gaagtatggc
      601 aatggttaga aaataacaat acacacttag aacgatttcg atggctacga gtaaaaacgg
      661 aaggattaaa gtgggaaaaa attatggaac aacattatca actatttgag gcattaacaa
      721 aacaagatcc agaagaagct aactttctaa catcgttgca tcttcattta atgcttaatg
      781 agcaaaatat tgttttagct actcatccaa aatatttcaa aaata
//
LOCUS       DAFLWC010000235          824 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.242, whole genome shotgun sequence.
ACCESSION   DAFLWC010000235 DAFLWC010000000
VERSION     DAFLWC010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 824)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 824)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..824
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.242"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(348..548)
                     /locus_tag="L1V17_003021"
     CDS             complement(348..548)
                     /locus_tag="L1V17_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBN1237702.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
BASE COUNT          295 a          129 c          131 g          269 t
ORIGIN      
        1 attgaaacat ccatctggaa tttgtctttt tcgttgcttt gctcataaaa atctgcatat
       61 tcatcactaa tattttttct aataaattct tccatcataa agatcacctc gaaaagagta
      121 tacgaacaaa cgttcttttt gtaaaggtgg aatttattat actaaataaa taggtgaaca
      181 agtacttgtg ccaaattatg tgccaaaaaa aatcgaattt aataaaacac aaacaaaaag
      241 aaatcctatt atgataacat ttcttataat aacaaacaca acagaagacg tgtaatagtt
      301 agtcaggaac gtacaaataa cccctgtatc ctttgcggta cagggggtta ttttgtataa
      361 gtagacattg tagtttctaa actgctatgt cctaaacgtt tcgatacgct aagtatattt
      421 actccttgat aaagtaaaat agatgcatgc gtatgtctta gtccatcaat aaacagtcga
      481 agagaaaata gggaaaaatt gattactaaa gaaaaactta ctaggtcgac ggtgtagttg
      541 attttcatac ttcaatagat tcgaattaaa cgatttcgat tggcttatac cagtcctatc
      601 caacgaaaga tatatcgttc ttaactctag cggtataact tgaagcttta cgtaaagcca
      661 atgggaatga actggagatg actttttatt atttttagta atagctgatg ggttaatact
      721 tacaactttc cttttcaaag taccatataa aaaaacggtg gggttgttta gcgaaataaa
      781 ggatctaagc caatagctta gatcctttat tctatgcttt atat
//
LOCUS       DAFLWC010000236          815 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.243, whole genome shotgun sequence.
ACCESSION   DAFLWC010000236 DAFLWC010000000
VERSION     DAFLWC010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..815
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.243"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(680..753)
                     /locus_tag="L1V17_003022"
     tRNA            complement(680..753)
                     /locus_tag="L1V17_003022"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(717..719),aa:Ile,seq:cat)
BASE COUNT          275 a          144 c          135 g          261 t
ORIGIN      
        1 catgaaaaat cctccagtgt gttttttatt attctacaca ccttattttt tctgtctagt
       61 ctagtgtagc cgattcatga ctgacgtgcc ggacgcacgt agcgatcatc ggcgttatga
      121 ctatataaag tatactttcg ttgatccaga aaggtataaa gattaaagta ggctacctaa
      181 aaaggtagcc cggaacgaat tttatcacca tacttgtgaa aggagatatt ttttaagtta
      241 gtattaagat tgtgtaatat gatgatatct atattttata gtatcagtgc tataaaatca
      301 aaaataagtc actaattaac taccactcca attgtaagcc ttttttctca ctttttttca
      361 aaaatatggt atgcttttta atggcttcaa atataaaaga gtttaaagcg taacacactt
      421 atggggaagt ggtttggggt gcgctttaaa ctcttcttta ttattatctc acaatttaac
      481 ccaaatgtct ttctatttaa aaatcaaagt aaaacttttc aaatatacag aagtataact
      541 atgtgaaaca tcctttcatt aatccataaa aggatacata aaaaagccac tcatttgagt
      601 ggcaatgaag aaaagcttta gcttgtataa tactcttcaa aaaaattcta acacagaacg
      661 attcaaatgg ctacgttaat gtaccctgta ggactcgaac ctacgaccgg acggttatga
      721 gccgtctgct ctgaccaact gagctaaggg tactggttgt tgccacataa agccataaac
      781 aatcaaccag tagaatgtgt ggcaacaaac ctgtt
//
LOCUS       DAFLWC010000237          788 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.244, whole genome shotgun sequence.
ACCESSION   DAFLWC010000237 DAFLWC010000000
VERSION     DAFLWC010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..788
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.244"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(58..130)
                     /locus_tag="L1V17_003023"
     tRNA            complement(58..130)
                     /locus_tag="L1V17_003023"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(95..97),aa:His,seq:gtg)
     gene            complement(133..206)
                     /locus_tag="L1V17_003024"
     tRNA            complement(133..206)
                     /locus_tag="L1V17_003024"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(172..174),aa:Trp,seq:cca)
     gene            complement(213..293)
                     /locus_tag="L1V17_003025"
     tRNA            complement(213..293)
                     /locus_tag="L1V17_003025"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(257..259),aa:Tyr,seq:gta)
     gene            complement(295..370)
                     /locus_tag="L1V17_003026"
     tRNA            complement(295..370)
                     /locus_tag="L1V17_003026"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(335..337),aa:Phe,seq:gaa)
     gene            complement(406..478)
                     /locus_tag="L1V17_003027"
     tRNA            complement(406..478)
                     /locus_tag="L1V17_003027"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(443..445),aa:Asp,seq:gtc)
     gene            complement(488..560)
                     /locus_tag="L1V17_003028"
     tRNA            complement(488..560)
                     /locus_tag="L1V17_003028"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(525..527),aa:Val,seq:tac)
     gene            complement(576..647)
                     /locus_tag="L1V17_003029"
     tRNA            complement(576..647)
                     /locus_tag="L1V17_003029"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(612..614),aa:Glu,seq:ttc)
     gene            complement(662..751)
                     /locus_tag="L1V17_003030"
     tRNA            complement(662..751)
                     /locus_tag="L1V17_003030"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(715..717),aa:Ser,seq:gga)
BASE COUNT          216 a          216 c          183 g          173 t
ORIGIN      
        1 catgagggag tcaaagtccc ttgccttacc gcttggctat accccaagaa taaaaagggc
       61 gaatgatggg aatcgaaccc acgaatgccg gagccacaat ccggtgcgtt aaccacttcg
      121 ccacattcgc catggcaggg gcagcaggaa ttgaacccac actaacggtt ttggagaccg
      181 ctgttctacc tttaaactat gcccctataa aatggaggag agtggattcg aaccactgaa
      241 ccctaaggaa cggatttaca gtccgtcgcg tttagccact tcgctactcc tccatggtgg
      301 cgcgggacag aatcgaactg ccgacacacg gagcttcaat ccgttgctct accaactgag
      361 ctaccgcgcc atattttaaa attattaatt gaataacaag aacgacggtt ccgacgggaa
      421 tcgaacccgc gatctcctgc gtgacaggca ggcatgttaa cccctacacc acggaaccag
      481 ttcattatgg aggttaacgg gatcgaaccg ctgaccctct gcttgtaagg cagatgctct
      541 cccagctgag ctaaacctcc aacattcaat taaaatgacc cgtacgggat tcgaacccgt
      601 gttaccgccg tgaaagggcg gtgtcttaac cgcttgacca acgggccagg taaatttgct
      661 acggagagta agggattcga acccttgaga cagtttggca ccatctacat gatttccaat
      721 catgctcctt cggcctctcg gacaactctc cagagtgaaa gaagctcaat actctttctc
      781 aaaatgag
//
LOCUS       DAFLWC010000238          726 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.245, whole genome shotgun sequence.
ACCESSION   DAFLWC010000238 DAFLWC010000000
VERSION     DAFLWC010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..726
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.245"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(47..433)
                     /locus_tag="L1V17_003031"
     CDS             complement(47..433)
                     /locus_tag="L1V17_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237703.1"
                     /translation="MKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRFEVLKIQKNE
                     LLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTDVVMITDIYV
                     EDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          226 a          133 c           85 g          282 t
ORIGIN      
        1 tttgttgatt taccaacatg tttagacatt tttctctagg aaaaaattaa ctagcaccac
       61 gggttccttt atttttatta acaagtttta tcacaggctt catatatttg attatatctt
      121 catcttctac atagatatct gttatcatta cgacatctgt actatttcga ttgagtactt
      181 tcacttgatc tccagcattg attttccctc taaatctttt aggaatgaac caactataca
      241 tatgattagc atcaccaaaa tgtgctttta tcgcattctc aggatataac ttattcaata
      301 gttcattctt ttgaattttc aaaacttcaa atctatactt atcatcttct gctaatctaa
      361 ataaatcttc taaacgcatg ttttctaact gtaagttttg aaaatcttcc ggtataaatt
      421 ttctatattt cattaataat gaacgcccag cccgatttat tagaatctgg ccattttggt
      481 catctctata aagaattccg taacccatca acgccaatag cacacgtgac gttttgttac
      541 ttgtaatatt catatttcct tgattacctg aggcaatgaa agacttatct acttgaatta
      601 gggtgaaatt ctcattcaaa tatggtagta aaattaatat atgtgaaaat cgaatcttga
      661 gatagctatt ccccttgaga tattcactga tacttctact caaatcattt aaatttttat
      721 aattat
//
LOCUS       DAFLWC010000239          661 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.246, whole genome shotgun sequence.
ACCESSION   DAFLWC010000239 DAFLWC010000000
VERSION     DAFLWC010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..661
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.246"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..>661
                     /locus_tag="L1V17_003032"
     CDS             <1..>661
                     /locus_tag="L1V17_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1237704.1"
                     /translation="EVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSEN
                     MVFVDYSTSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDS
                     NAFEESLESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKI
                     QIIMQFIFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSN
                     IT"
BASE COUNT          258 a           59 c          112 g          232 t
ORIGIN      
        1 gaagttgatc ttgaattact agatattgaa aaaagtggaa aaataaaaag tcataaattt
       61 aaaattatag ggatcttttc tggtaaaaaa caggaaacat atacaggatt atcttctgat
      121 tttagtgaaa atatggtgtt tgtagattat tcaacaagcc aagagatatt aaataattca
      181 gaaaataatg aaattgcaaa taaaatttta atgtattctg gtagtgcaga atctacagac
      241 ttagccttaa acaaattgaa agagcttaaa attgatgagt caaagtattt tgttgaaaaa
      301 gattctaatg cgtttgaaga gtctttagag tcagtgagtg gaataaaata tataataaaa
      361 gtaatgactt attctattat gttaggtggg atggttgttc tttcattaat cttgattcta
      421 tggttaaggg aaagaattta tgaaataggt atattcttat ctattggaac atctaagata
      481 caaattataa tgcaatttat attcgagtta atattcatat cgataccaag tataatatct
      541 tccttatttt taggaaatgt attactaaaa gtaattgtag atggattcat taactcagag
      601 gattcaatga tttccggtgg aagtttaata aataatagta gttttatgtc aaatataaca
      661 a
//
LOCUS       DAFLWC010000240          627 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.247, whole genome shotgun sequence.
ACCESSION   DAFLWC010000240 DAFLWC010000000
VERSION     DAFLWC010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..627
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.247"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(205..570)
                     /locus_tag="L1V17_003033"
     CDS             complement(205..570)
                     /locus_tag="L1V17_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237705.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
BASE COUNT          243 a           84 c          115 g          185 t
ORIGIN      
        1 aatattatag atgtttccac ctcaaattca atatctatta ttggaatcat tattgctgca
       61 attattacac aactgttttt agtgtttgga gagaagaaaa gaagtaaaaa atagaaaaac
      121 tagtgatagt tttggtgata taagaaaaac atatatgtat aaaaagaaga aagtagcttc
      181 tctttgtaca tatatggttt gtttttatgg atgccgagct tttttataag ataaggctac
      241 cgcccataac gacccaagga tttgtggaac taagtaaata cctgcaagaa gcaagatcag
      301 ctgggtcggt tttaaaggat gatagaagta acgccattca gtaaaattgg cgcaaaataa
      361 ataggaagtg acagtagata taatattggc aatgaataaa gatataatac gcctgttcct
      421 ttgaaaataa tatccagcaa aaagagataa aaatatcaat gtgatgaacc cgcttacgga
      481 atgataacga aaatcaagca gtaaggcgaa atgcacataa ggaacaaaag ataaaagcaa
      541 cggaaggttt ttccagcaag tttttatcat ctttcatcac cacctaacaa gtgttattat
      601 tttgttagtt ttattgtaaa ttgaatc
//
LOCUS       DAFLWC010000241          625 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.248, whole genome shotgun sequence.
ACCESSION   DAFLWC010000241 DAFLWC010000000
VERSION     DAFLWC010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.248"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            1..625
                     /locus_tag="L1V17_003034"
                     /pseudo
     CDS             1..625
                     /locus_tag="L1V17_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
BASE COUNT          247 a          105 c          118 g          155 t
ORIGIN      
        1 gtaaagcaat ctaaaacgag tggttcattc aaagaaaaag ataatcttac gcctgaacaa
       61 aaagaattgt tagaactacg taaaagaaac cagcaattag aaatggaaaa tgatatttta
      121 aagcaagcag cgctgatatt cggacgaaga gacaagtaat cgatgcgaat aagcatcttt
      181 accctatatc agcgatgtgc agaatattag gtctatcacg tcagtcctat tattatcaat
      241 caaaaccaaa gaaagacgaa tcagaacttg aagaagtagt cgctgaagaa tttatccgca
      301 gccgaaaggc ctacggctca agaaaaataa aaaaagcctt atcaaaacga ggcattcaga
      361 tcagccgacg aaaaattagt agaatcatga aaaatagagg attaaaatcg agctatactg
      421 ttgcttattt taaagtacat cattctactt gcaatgaagc caaaacgaca aacgtattga
      481 atcgtaaatt cttaagagac aacccattag aagcgatcgt aacagacttg acttatgtac
      541 gagtcgggaa aaaatggaat tatgtctgtt tcattttgga tctgttcaat cgagaaattc
      601 tcggctattc ttgtggagaa cataa
//
LOCUS       DAFLWC010000242          619 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.249, whole genome shotgun sequence.
ACCESSION   DAFLWC010000242 DAFLWC010000000
VERSION     DAFLWC010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..619
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.249"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            73..234
                     /locus_tag="L1V17_003035"
     CDS             73..234
                     /locus_tag="L1V17_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBN1237706.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            253..>619
                     /locus_tag="L1V17_003036"
     CDS             253..>619
                     /locus_tag="L1V17_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBN1237707.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEAT"
BASE COUNT          254 a           61 c          108 g          196 t
ORIGIN      
        1 catgaaaaat cctccagtgt gttttttatt attctacaca ccttattttt tctgtctagt
       61 ctagtgtagc cgattcagga taaggataag tgtattaatt gtggaaaatg taaaaaagtt
      121 tgccaaatga ataaagattc agttgagaat tgcaatcatc tggagtgtat cagatgtgga
      181 cgatgtaaaa atgcttgtcc agtggatgca attagttatg gagtaagaaa atagagagga
      241 gtagttagga aagtgataaa aaatgctata gcatatatta caagaaagaa aaatagaact
      301 ttaataattt ttatcatatt aactatagtt ctttcttgct tgtattcttg tttaacaata
      361 atgaaatcaa gcaatgaaat agaaaaggct ttatatgaaa gttctaattc ttcaatatca
      421 ataacaaaaa aagatggtaa atattttaat gttaatcaat ttaaagatat tgaaaaatta
      481 aaagaaattg aagaaaaaat aattcaatat gatggattag caaaactaaa agatgctaaa
      541 gtagttagcg gagaacaaag aataaataga gaagatttat ctgacgaatt taagaatgtt
      601 gtttcactcg aagctacaa
//
LOCUS       DAFLWC010000243          608 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.250, whole genome shotgun sequence.
ACCESSION   DAFLWC010000243 DAFLWC010000000
VERSION     DAFLWC010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..608
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.250"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..>608
                     /locus_tag="L1V17_003037"
     CDS             <1..>608
                     /locus_tag="L1V17_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237708.1"
                     /translation="KFANSFWFLKNINKTVEKNGVYKGDFHFQNAETIEREHHYFDLL
                     VNTVVELAKWAKSNETYSQVLKRIMSQETSFIYELSKSNLKYTYNEDELEILDNPENS
                     QWIKELKREDFIETLRILKSLFDLKLAKATIMGIERDSYYWEEIGLYAPQIEGEDKEK
                     RIDNIINYINSLSEPLKCRGLDFIGTLGWTETYYEKIYKEII"
BASE COUNT          253 a           62 c          110 g          183 t
ORIGIN      
        1 ctaaatttgc aaactcattc tggtttttaa aaaatattaa taaaacagtg gaaaagaatg
       61 gagtttataa aggtgatttt cattttcaaa atgctgagac tattgaacga gaacatcatt
      121 atttcgattt attagtgaat acagtggtag aattagcgaa atgggcaaag tcaaacgaaa
      181 cttatagtca agtacttaaa agaattatga gtcaagaaac ttcatttatc tatgagttaa
      241 gcaagtcaaa tttgaaatat acttataatg aagatgaact tgaaatttta gataatccag
      301 aaaattcaca atggattaaa gagttgaaga gagaagactt tattgagaca ctaagaattc
      361 taaaatcgtt atttgatttg aaattagcca aagctaccat catgggaatt gaaagagatt
      421 catattattg ggaggaaatt ggactatatg ctccccagat tgaaggtgaa gataaagaga
      481 aaaggataga caacattatt aactatatta atagtttaag tgaaccttta aaatgtagag
      541 gacttgattt tataggaaca ttaggatgga cagaaacata ctatgagaaa atatataaag
      601 aaataatt
//
LOCUS       DAFLWC010000244          577 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.251, whole genome shotgun sequence.
ACCESSION   DAFLWC010000244 DAFLWC010000000
VERSION     DAFLWC010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..577
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.251"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(32..>577)
                     /locus_tag="L1V17_003038"
     CDS             complement(32..>577)
                     /locus_tag="L1V17_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBN1237709.1"
                     /translation="IHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYLDPFMD
                     MFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGWAYQMKAYRNKLK
                     EYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCFEELKSAIDSYIYYYNNER
                     IKQKLNWQSPVQFRKTTVTVV"
BASE COUNT          164 a          108 c          100 g          205 t
ORIGIN      
        1 actccttttt tcatgctcta aaatgatatt tttacacaac tgttacggtt gttttacgaa
       61 attggacggg actttgccag tttaatttct gttttatccg ttcattattg tagtaataga
      121 tatagctatc gatggctgat tttaattcct cgaaacagtt ataaactttc ccgtgaaaaa
      181 tctcttgttt taataagcca aaaaaattct ccataagtga attatctaag cagttccctt
      241 tccgagacat gctttgaaag attttgtact ccttcaattt gtttctataa gctttcattt
      301 gatacgccca accttgatct gagtgaaacg tacgacgata gggacaatcg ttagtggtct
      361 ggatagcttc ctccaaacct tccattaccg ctaatgcatt gggcttttca gagatacgat
      421 aggataaaat ctcactattg aacatatcca taaaaggatc tagatacaat ttcttttgac
      481 ggataatgcc tttggcatcc acttcatggt atttaaattc agttgtatcc gtcgtgattt
      541 tctgatggca gatactggtg tagaaacgac gatggat
//
LOCUS       DAFLWC010000245          575 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.252, whole genome shotgun sequence.
ACCESSION   DAFLWC010000245 DAFLWC010000000
VERSION     DAFLWC010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..575
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.252"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
BASE COUNT          186 a           81 c           81 g          227 t
ORIGIN      
        1 tttttcttga tgtgatatcc ttgtcttttt tgtaatgttt ttaacttatt gcttttgcaa
       61 aatttattta cctgttttct ggatcaacga tagtgtacat tatgctatcc ttgtttggat
      121 tttaggacgt ttaaagaggc acttttttac ataacttaat ccatagacct tttaagcatg
      181 ctgtgagata ataataaaga agagtttaaa gcgcacccca aaccacttcc ccataagtgt
      241 attacgcttt aaactctttt atatttgaat tcactaagaa gcataccata tttttgaaaa
      301 aaagtgagaa aaaaggctta taattaggat ttagagtaat taattagatg tttattttat
      361 aggactgata ctatagatta caaatagtat cgtatttcgc aatcttaaaa ttatcttctt
      421 actgtgaata agataataaa atttgtattt gtccttttta ggtaacttat tttaatctat
      481 atacctttct ggatcaacga aagtatactt tatatagtca taacgccgat ggtaactatg
      541 cactgtaacg ataatgctgc taaaatatct tttta
//
LOCUS       DAFLWC010000246          536 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.253, whole genome shotgun sequence.
ACCESSION   DAFLWC010000246 DAFLWC010000000
VERSION     DAFLWC010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..536
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.253"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            112..306
                     /locus_tag="L1V17_003039"
     CDS             112..306
                     /locus_tag="L1V17_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237710.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
BASE COUNT          227 a           68 c           87 g          154 t
ORIGIN      
        1 aaaactttca aattgattct ttttatttat cataaagata tagatacata atcattttca
       61 cttacatata tttgaatatt aactaaaaac agcaagaaag aagaggatca aatgtattat
      121 gtagaagtaa aaacaaaagg cgtcaaaaac aaacaatatg tgaaaggtat cagtaacgaa
      181 tatcctttac ttggttcatg gaaagaagct gctccttttt ccaaaccatg tgccataaaa
      241 ataaagaacg agctagaaaa agaactgact tgtggtaaag ctgttgtaga tatcatcgaa
      301 aagtaaatcc aatgtataga aaggaagatc acacatgaaa agcgacgtac aaattgctaa
      361 gattatagaa ttagaagaag aagacgcagt gttgacaatt gaaaaaaaat aaatgtttgt
      421 ataccatatg attatttcaa tatgtatcct ggaattggag atctcgtaga gctatatcaa
      481 gatgaatcaa atatacttgt cattcatcat gaaatataga gacttataaa attgtt
//
LOCUS       DAFLWC010000247          534 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.254, whole genome shotgun sequence.
ACCESSION   DAFLWC010000247 DAFLWC010000000
VERSION     DAFLWC010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.254"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..>534
                     /locus_tag="L1V17_003040"
     CDS             <1..>534
                     /locus_tag="L1V17_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HBN1237711.1"
                     /translation="DGFKACTDPRQAAYAFERNYERPAATHPERQDYAVNWYNKFKDL
                     KPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYSGYLGGCGMGAGTKYGLTHVIGNT
                     SAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIINWARGGQVGSWFADGTYGHTGVIR
                     GLANGRMQTYEQNTELG"
BASE COUNT          163 a           80 c          137 g          154 t
ORIGIN      
        1 tgatggattt aaggcctgta ctgatccaag acaagcagca tatgcttttg aacgaaacta
       61 tgaacgtccg gcagcgacac atcctgaacg tcaagattat gcagttaact ggtataacaa
      121 atttaaagat ttaaaaccag gaggagctac tggagaagca ggactaaaac atttagagtc
      181 tttgattgga caacgaattg gcaatggtca gtgttatggc ttgtctgcag aatattcagg
      241 atatctgggt ggttgtggca tgggtgctgg aacaaaatat ggtttaactc atgtgatagg
      301 aaatacttct gcagcatctg atattggtat tgcctatgat tggtctgctg ttggttggaa
      361 agtgattcaa aaccctagat atgatcaatt agtagttggt gcaattatta attgggcaag
      421 aggtggacaa gtgggttcat ggtttgcaga tggaacttat ggacatactg gcgttatccg
      481 aggcttagct aatggtcgta tgcaaactta tgaacaaaac acagagttag gtat
//
LOCUS       DAFLWC010000248          514 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.255, whole genome shotgun sequence.
ACCESSION   DAFLWC010000248 DAFLWC010000000
VERSION     DAFLWC010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.255"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
BASE COUNT          175 a           98 c           59 g          182 t
ORIGIN      
        1 aacacagtta tttttaaaaa taagaatgct aaatcactct acaataacgg cgaaagcaca
       61 aaaaataaaa aaattattac gttattaaaa aaacagatga aagatcaggt tttattagat
      121 ctcattcttt catcacttga agggatttaa tgaactactt tttcctcttt gtcgttttta
      181 tatattcgta ttccttcaaa cagtaggata gcctctttca atgcttgata tttgaactgt
      241 ccgttactta aaaatttaga tgtgccgccc tcttcctaga acatattctt ttttactttt
      301 tcattaattg acagaccaat cgaacgaaac tgtaaatttc gataggataa tgattggtca
      361 aactcattca ttttcaagac atctcgattc atattcaaga taggaatctt tttatcaaca
      421 tcactttatt cgtattttcc tctaccataa aagcttcacg ctccacaaaa ttgttttata
      481 cactactatt cagcccattc aacgaccaat gaat
//
LOCUS       DAFLWC010000249          481 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.257, whole genome shotgun sequence.
ACCESSION   DAFLWC010000249 DAFLWC010000000
VERSION     DAFLWC010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.257"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..231)
                     /locus_tag="L1V17_003041"
     CDS             complement(<1..231)
                     /locus_tag="L1V17_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237712.1"
                     /translation="MATNYAKKINFDVDKLYKSLIVVPKNKSEDGNYELEVLQFKIEQ
                     KSSERFMSNQLVKIKKWLPMIDQLVSNNKEAKN"
BASE COUNT          157 a           88 c           51 g          185 t
ORIGIN      
        1 atttttagct tccttattat tagatactaa ttgatcaatc atagggagcc attttttgat
       61 tttcactaat tgattgctca taaatctttc actggacttt tgttcaatct taaattgcaa
      121 aacttctaac tcataattcc catcttctga tttatttttg ggaacaacta tcaaactttt
      181 ataaagttta tccacatcaa aatttatctt ttttgcataa tttgtagcca ttaatacatc
      241 tccttattca taataaattt catatgacgc tcctctcaaa atttaccggt agactagaaa
      301 aaagaataaa agatacgtca attcacactt tattcttaaa aaaaaactgg tctctctacc
      361 ggtaatatcg attgagtccg cctttatcga ctttatcctt tttttatatt aaattttttc
      421 accggtagac agggagagaa agaataaact aaaaagccct taattcttaa tgttttcacc
      481 t
//
LOCUS       DAFLWC010000250          471 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.258, whole genome shotgun sequence.
ACCESSION   DAFLWC010000250 DAFLWC010000000
VERSION     DAFLWC010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.258"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..>471
                     /locus_tag="L1V17_003042"
     CDS             <1..>471
                     /locus_tag="L1V17_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237713.1"
                     /translation="AGEGTSIESGTTVFAVKDGVSLPEDKLPVLKAKDGYTDAKWPEE
                     ATQPITADDTEFVSSATKLDDKSDADKYNPEGQKVTTELNKEPDAFEGIKNKEDLPKD
                     TKYTWKEKVDVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEG"
BASE COUNT          191 a           70 c          112 g           98 t
ORIGIN      
        1 cgcaggagaa ggaacaagta ttgaaagtgg aacaacagtc tttgcagtga aagacggcgt
       61 aagcttacca gaagataaac ttccagtgtt gaaagcaaaa gatggttata cagatgcgaa
      121 atggccagag gaagcaactc aaccaattac agcagatgat acagaatttg tatcaagtgc
      181 aacaaaactg gatgataaat ctgacgctga caaatataat cctgaaggtc aaaaagtgac
      241 tacagaattg aataaggaac cagacgcatt tgagggaatt aagaacaaag aagatttacc
      301 aaaagatact aagtatactt ggaaagaaaa agtagatgtt agcgcagctg gaaataaaaa
      361 agggactgtt gtagtgacat atccagatgg atcatctgat gaagttgaag tagatgttac
      421 agtgacagac aatcgttctg acgccgataa atatgagcca acagtagaag g
//
LOCUS       DAFLWC010000251          468 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.259, whole genome shotgun sequence.
ACCESSION   DAFLWC010000251 DAFLWC010000000
VERSION     DAFLWC010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.259"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..>468
                     /locus_tag="L1V17_003043"
     CDS             <1..>468
                     /locus_tag="L1V17_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HBN1237714.1"
                     /translation="CVIWGIINGYTSQRATYRAVCSVLFPNGDFPSRSRFTRLSSNLA
                     YTIKIIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYF
                     YGLKIHMIVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHK"
BASE COUNT          155 a           86 c           83 g          144 t
ORIGIN      
        1 cttgtgttat atggggcata attaatggct atactagcca aagagccacg tatagagcgg
       61 tttgttccgt cttatttcct aatggtgact ttcctagtag gagtcgattc actcgcttaa
      121 gttcaaactt agcttacact atcaagatta ttcgatactt tttcatcaag aagctcacca
      181 aaggtgaact agtcggaatt atagatagtt ttcctagtcc attatgtaaa ccagttagaa
      241 atagacaagc aaaactattg aatcaaatag ccaaagttgg ctataactca acaaaaaaat
      301 cttattttta tggtcttaaa attcatatga tcgttactaa gactggcttt ccgattactt
      361 actcaatcac gaatccaggt gtccatgacg tgaaagtgtt agagacttta tcggaagaag
      421 cgaatcttcc caatatccta ggggacaaag gatatattag ccataaaa
//
LOCUS       DAFLWC010000252          464 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.260, whole genome shotgun sequence.
ACCESSION   DAFLWC010000252 DAFLWC010000000
VERSION     DAFLWC010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.260"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..>464
                     /locus_tag="L1V17_003044"
     CDS             <1..>464
                     /locus_tag="L1V17_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1237715.1"
                     /translation="LVTKGDLNELFRSHLEKAINTLLRTELTAFLDYEKYDRTGFNSG
                     NSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLETTIIHLFEKGVT
                     MSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAIFMDAT"
BASE COUNT          168 a           85 c           77 g          134 t
ORIGIN      
        1 ctagtcacta aaggcgattt aaatgaatta ttccgttcgc acttagaaaa agcgataaac
       61 acactcctac ggactgaatt aacggctttt ttagattacg aaaaatatga tcgcactggt
      121 tttaattcag gtaattcgag aaacggttct tactttcgat caatcaaaac cgaatatggt
      181 gaattaacat tggaaatacc tagagatcgt aatggtgagt ttaaacaaca aactttacca
      241 gcctacaaaa gaacaaacga tacattggaa accactatta tccatttatt cgaaaaaggt
      301 gttacgatgt ctgaaattgc tgatttgatc gaaaaaatgt acggtcatca ctatactcca
      361 caaaccatgt ccaacatgac taaagttctg actgaagaag taaatgcctt taaatccaga
      421 gccttaaatg ataagtatgt cgctattttt atggacgcta ctta
//
LOCUS       DAFLWC010000253          396 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.261, whole genome shotgun sequence.
ACCESSION   DAFLWC010000253 DAFLWC010000000
VERSION     DAFLWC010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.261"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(91..>396)
                     /locus_tag="L1V17_003045"
     CDS             complement(91..>396)
                     /locus_tag="L1V17_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1237716.1"
                     /translation="TIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQYQF
                     ETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT          107 a           95 c           78 g          116 t
ORIGIN      
        1 ttgtgaatgc tgcggtgtta tggctacgat tgcccttgac aatgagcatc ctcggatctg
       61 attttctccg gcagaagcac aatcattcaa ttacgctgcc tctccagagg tatcagatcc
      121 gcgctcatta tcaaggattc gcttcgccaa tctctgttgt cgaatttgga tcggtgtttc
      181 atacgccaac gtgccatgta agcgtagata gttccaccaa tgcacataat caaacaattc
      241 tagacgtagc tgtgccagtg tctcaaattg gtattgatgc acgaattcta ctttgacaga
      301 tttataggtt gattccacaa cggcattatc atacggacaa cccttcctac tcaatgaacg
      361 agtaattcca aaaccattca gaatctcatg aatggt
//
LOCUS       DAFLWC010000254          375 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.262, whole genome shotgun sequence.
ACCESSION   DAFLWC010000254 DAFLWC010000000
VERSION     DAFLWC010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.262"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..>375)
                     /locus_tag="L1V17_003046"
     CDS             complement(<1..>375)
                     /locus_tag="L1V17_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237717.1"
                     /translation="PYQPNLLDDPYWLGKAPLGENIANKSVTFPIKSSAYSLYQANME
                     EEFVLGQTYTITMKATKPPIQTFIVYNEDSGDYRYGNLEPVEGLVDTWGLTFTPQKVG
                     VNYPKRLTIIQYPQSTTGACQID"
BASE COUNT          100 a           73 c           80 g          122 t
ORIGIN      
        1 gtcaatttga catgcacctg ttgttgattg gggatactgg ataatagtta accgtttggg
       61 gtagttaact ccaaccttct gcggtgtaaa agtcagaccc catgtatcaa ctaacccttc
      121 tactggctct aagttaccat atctataatc tccactatcc tcgttgtaaa caatgaacgt
      181 ttggataggt ggtttggttg ccttcatggt aattgtatag gtttgaccta aaacaaattc
      241 ttcttccatg ttagcttggt ataggctgta ggcgctagat ttgattggaa acgtaacaga
      301 cttattagca atattctcac ccaaaggcgc tttacctagc cagtaagggt catcaagtaa
      361 gtttggctga tatgg
//
LOCUS       DAFLWC010000255          342 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.263, whole genome shotgun sequence.
ACCESSION   DAFLWC010000255 DAFLWC010000000
VERSION     DAFLWC010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..342
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.263"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(70..315)
                     /locus_tag="L1V17_003047"
     CDS             complement(70..315)
                     /locus_tag="L1V17_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBN1237718.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
BASE COUNT          102 a           78 c           58 g          104 t
ORIGIN      
        1 tattcttagc ataccgattc gcacacaaaa aagcaaacga accttacgaa tctcaggctc
       61 gtttgctttt taaactgctt cagttaaaaa ttcgatctca actgtccgag taagtacatc
      121 tgaatagctg taagatactc gttcaaaaga attttcttca ggatccaaat caacaacgaa
      181 tactgaagga taggtttctg ttaaaacgcc gcggcgttct gtttgacgct ttcttcctgt
      241 ctgagcaacc aacatgattg ggctgccgat acgaccttct aaatctttct tgattgaagc
      301 taaagttgtt ggcatacagt tcacctctac tatcaactat ac
//
LOCUS       DAFLWC010000256          333 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.265, whole genome shotgun sequence.
ACCESSION   DAFLWC010000256 DAFLWC010000000
VERSION     DAFLWC010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.265"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            162..272
                     /locus_tag="L1V17_003048"
                     /pseudo
     CDS             162..272
                     /locus_tag="L1V17_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          114 a           56 c           40 g          123 t
ORIGIN      
        1 acatctttca gcattttact atatttggta tatagtgcta aggttcatat tcgattgaca
       61 agagaatata aattgatcta tttctatttc ctaagttgag taaacataac tttgcccttt
      121 ataaatatct tccctctctc tcttctctct atattttata tttgaataat catatcaagg
      181 tattccaacg aaatgccaat ggatttcgaa gcttttataa ctttaaatta cggatcatga
      241 tttggcatgg ggaatcatta ctaataaaat aaaaaaatga acagaaagaa aacagttctt
      301 tctgttcacc aacttcattt gacaaatatc cta
//
LOCUS       DAFLWC010000257          321 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.266, whole genome shotgun sequence.
ACCESSION   DAFLWC010000257 DAFLWC010000000
VERSION     DAFLWC010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.266"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(69..321)
                     /locus_tag="L1V17_003049"
                     /pseudo
     CDS             complement(69..321)
                     /locus_tag="L1V17_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT           79 a           78 c           51 g          113 t
ORIGIN      
        1 tccaaactcg taactcgagc ttggaacagc tttttatcta cttcgtttcg aatttttgaa
       61 caaaaaaata aaggctcctt gcctttccat agccaggtgg ctaatttctt taaattcatt
      121 gcagcaaaca ctagcatcgt atgcgtcgcg actttttcca agcctcgata cttggtccaa
      181 cgcatcccat gcttttcttt tgcatccgca aatattcgtt caatcgtttg tttccgtttt
      241 ttgtaaattg atttattcag atctgttagg cgaagatgtt ccacttcatc catcagatct
      301 ccccaaacat gtctcgtgat g
//
LOCUS       DAFLWC010000258          317 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.267, whole genome shotgun sequence.
ACCESSION   DAFLWC010000258 DAFLWC010000000
VERSION     DAFLWC010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.267"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
BASE COUNT          114 a           34 c           59 g          110 t
ORIGIN      
        1 taagaaggag tataaaaatg aacaaacata atagaaaaat aacgaataac aaagaactga
       61 tcttgttact aatagggatt tggggtatct ttttactctt taatatgtat atgccgacta
      121 tgagagcgga tgacgtagtt tatgcaagta gattagatga acttggctat ttgggtgctt
      181 cgatagaaca ttataagaca tggagttcaa gaattattat agaactattc ttaatgttct
      241 tttctaaaca ctttatgcta tggaaattat taaattctac gattatgtta ggaattgtag
      301 tattactttg caagtat
//
LOCUS       DAFLWC010000259          283 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.268, whole genome shotgun sequence.
ACCESSION   DAFLWC010000259 DAFLWC010000000
VERSION     DAFLWC010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..283
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.268"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            1..283
                     /locus_tag="L1V17_003050"
                     /pseudo
     CDS             1..283
                     /locus_tag="L1V17_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          109 a           57 c           56 g           61 t
ORIGIN      
        1 aacaaatcgt cgatctctat ctcgctggta agcctcgcgc agaaattatt cgagagtatg
       61 agcttacgcc ttcttctttc gataaatgga tgaagcaagc acaatcaacg ggctcattca
      121 aagaaagaga caacttaaca ccagaacaag cagaattgat cgcactaaga aagaaaaata
      181 agcaactcga aatggagaat gatattttaa agcaagcggc gctgatattc ggacgaaaag
      241 acaagtaatt gatgccaaca agcataaata ttccatatca gcg
//
LOCUS       DAFLWC010000260          282 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.269, whole genome shotgun sequence.
ACCESSION   DAFLWC010000260 DAFLWC010000000
VERSION     DAFLWC010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.269"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..>282
                     /locus_tag="L1V17_003051"
     CDS             <1..>282
                     /locus_tag="L1V17_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HBN1237719.1"
                     /translation="QSKRLFPEINCVVADAGYKTPKFVHFLTHLNLRPCLPYSRPKGK
                     KGLLSKNEFLYDEYFDCYICPQDQMLAFSTVTREGYREYKSNPKECVNC"
BASE COUNT           84 a           52 c           56 g           90 t
ORIGIN      
        1 aacaatcgaa gagacttttt cctgaaatca attgtgttgt cgctgatgct gggtataaga
       61 cacctaagtt tgttcacttt ttgactcatt tgaaccttcg accttgtttg ccttattcaa
      121 ggcccaaagg gaaaaagggg ctattatcaa aaaatgagtt tctctatgac gagtattttg
      181 attgttatat ttgtccgcaa gatcaaatgc tcgctttttc aacggttact cgagaagggt
      241 accgagaata caaatccaat ccaaaagaat gtgtgaactg tc
//
LOCUS       DAFLWC010000261          268 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.270, whole genome shotgun sequence.
ACCESSION   DAFLWC010000261 DAFLWC010000000
VERSION     DAFLWC010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..268
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.270"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(36..>268)
                     /locus_tag="L1V17_003052"
     CDS             complement(36..>268)
                     /locus_tag="L1V17_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBN1237720.1"
                     /translation="LKNLPETLDAQLRTKLQNLLTYEEGIYNAMIYPYSNGKIEAKIP
                     HIKTLKRLSYGFKSFENMKIRIFLINQLIQVK"
BASE COUNT           79 a           39 c           47 g          103 t
ORIGIN      
        1 atagaaggac tgaccttctg tctcagattt ttttgttatt tcacttgaat caattgattg
       61 atcaaaaaaa tcctgatttt catgttctca aatgatttaa atccataaga taatcgtttc
      121 agtgtcttga tatggggaat cttggcctct attttgccat tagaatacgg gtaaatcata
      181 gcattgtaaa taccttcttc atacgttaaa aggttttgaa gtttcgtgcg aagttgtgca
      241 tcaagtgttt caggaagatt ttttaata
//
LOCUS       DAFLWC010000262          266 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.271, whole genome shotgun sequence.
ACCESSION   DAFLWC010000262 DAFLWC010000000
VERSION     DAFLWC010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..266
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.271"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            40..>266
                     /locus_tag="L1V17_003053"
     CDS             40..>266
                     /locus_tag="L1V17_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBN1237721.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYS"
BASE COUNT          118 a           27 c           47 g           74 t
ORIGIN      
        1 cctaaagaaa tcttatcaaa aataagttag gagaaaataa tggatatatt agaaataaag
       61 aatgtagcat atagttatgc aaattctaaa gaaaaagttt tgtcaggagt aaatcaaaaa
      121 tttgaacttg ggaagtttta tgcgatagta ggaaagtcag gaacaggaaa atctacactt
      181 ctttccttac ttgctggact tgataaacct caaacaggaa aaatattgtt taagaatgaa
      241 gatatacaaa ataaaggata tagtaa
//
LOCUS       DAFLWC010000263          253 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.272, whole genome shotgun sequence.
ACCESSION   DAFLWC010000263 DAFLWC010000000
VERSION     DAFLWC010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..253
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.272"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            28..>253
                     /locus_tag="L1V17_003054"
     CDS             28..>253
                     /locus_tag="L1V17_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HBN1237722.1"
                     /translation="MLGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWD
                     GKVYVQNLFNAAGIKEPITSLDAQVRLLIWT"
BASE COUNT           80 a           40 c           58 g           75 t
ORIGIN      
        1 ggatttacga aacaatctgc atgtggaata ttggggaaca ttcaacaaga aacaggagga
       61 acttttgatc ctgatactgt tcaaataggt ggaccagcat acggattagt tcagtgggat
      121 ggttcttcat atcctcttgt tggtccagca acatgggatg gaaaagttta tgttcaaaac
      181 ttatttaatg ctgcaggtat taaagaacca ataacgagct tagatgcaca agttcgattg
      241 cttatttgga cat
//
LOCUS       DAFLWC010000264          248 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.273, whole genome shotgun sequence.
ACCESSION   DAFLWC010000264 DAFLWC010000000
VERSION     DAFLWC010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..248
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.273"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            66..>248
                     /locus_tag="L1V17_003055"
     CDS             66..>248
                     /locus_tag="L1V17_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBN1237723.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTS"
BASE COUNT          107 a           39 c           38 g           64 t
ORIGIN      
        1 tgaaaatatt tatcataatt tttaatagaa aacactatta aagagaaaaa agagaggtaa
       61 atcaaatgaa aaaatcttta aaacttgcat cagcagttat attaatgtcc caactcctta
      121 tagcaacacc tttccatgtg ttggcaagcg aaaattcaac atacaaaatt gcaaaagaaa
      181 gaaccgagac gactgaaatg agtaattccg atgtaacagc agagagtagt gaacttttga
      241 caacttca
//
LOCUS       DAFLWC010000265          247 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.274, whole genome shotgun sequence.
ACCESSION   DAFLWC010000265 DAFLWC010000000
VERSION     DAFLWC010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..247
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.274"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            <1..>247
                     /locus_tag="L1V17_003056"
     CDS             <1..>247
                     /locus_tag="L1V17_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBN1237724.1"
                     /translation="PIENESDLEEIVQEEFIRNRKAYGTRKLKKCLAKRGLQLSRRRI
                     GRIMKRRGLTSTYTIAHFKGQRTACNEAKTANVLDRTF"
BASE COUNT           80 a           51 c           61 g           55 t
ORIGIN      
        1 ccgatcgaaa atgagtccga cttagaagag atcgttcagg aagagtttat tcgaaaccga
       61 aaggcttacg gtacccgaaa attgaagaag tgtttagcaa agcgtgggct tcaactcagt
      121 cggcgccgaa tcggtcgaat catgaaacgc cgcggattga catctaccta tacgatcgct
      181 cattttaaag ggcaacgaac agcttgtaat gaagcgaaaa cagcgaatgt attagatcgg
      241 accttta
//
LOCUS       DAFLWC010000266          244 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.275, whole genome shotgun sequence.
ACCESSION   DAFLWC010000266 DAFLWC010000000
VERSION     DAFLWC010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..244
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.275"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(68..>244)
                     /locus_tag="L1V17_003057"
     CDS             complement(68..>244)
                     /locus_tag="L1V17_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237725.1"
                     /translation="NLYYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYD
                     YLKYTFVDPERYKD"
BASE COUNT           73 a           47 c           39 g           85 t
ORIGIN      
        1 aaaaatatcc cttttataag tatggtgata aaatccgttc cgggctacct tttttaggta
       61 gcctacttta atctttatac ctttctggat caacgaaagt atacttcaaa tagtcataac
      121 gccgatgatc gctccgtgcg tctggcacat cagtcacgat atcaaacaaa aaatacacat
      181 ctttcttcat tctggttttt gttgccggaa ttttaaagta gttcttatta gagtaataga
      241 gatt
//
LOCUS       DAFLWC010000267          241 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.276, whole genome shotgun sequence.
ACCESSION   DAFLWC010000267 DAFLWC010000000
VERSION     DAFLWC010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..241
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.276"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..220)
                     /locus_tag="L1V17_003058"
     CDS             complement(<1..220)
                     /locus_tag="L1V17_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBN1237726.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFP"
BASE COUNT           63 a           45 c           46 g           87 t
ORIGIN      
        1 caggaaaaat gatttcggtt ctcccacaac gtcgcttatt ttctttgtat tgttcaaagt
       61 attcaagtgc tgttccacca catttgagaa agttatagac attgtaaatt gtttggcgtc
      121 cacgtttaag ctgcttcgca acgatagcaa ccggagtttc ttgatgaaaa tatgcttcta
      181 tcattacaag ctcgtttggt gtaagatggg tataagtcat ttatgttcac tctccttgta
      241 t
//
LOCUS       DAFLWC010000268          233 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.denovo.277, whole genome shotgun sequence.
ACCESSION   DAFLWC010000268 DAFLWC010000000
VERSION     DAFLWC010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..233
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.denovo.277"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
BASE COUNT           79 a           35 c           45 g           74 t
ORIGIN      
        1 tgagaaaaag catggaatgc gctgcatcag gtatcgaggc ttagaaaaaa atcaggtgca
       61 tacgatgctt gtttttgccg aaatgagtct gaaaaaattg gtcacttagc agtgggagca
      121 tatgtcttca tattttttat tatacaaaaa tagacaaaag tatcagtcta cactcttagt
      181 aaagaggaaa ctgatacttt tgtctacagt atgatatttc ttacatctac ttt
//
LOCUS       DAFLWC010000269        28619 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.guided.030, whole genome shotgun sequence.
ACCESSION   DAFLWC010000269 DAFLWC010000000
VERSION     DAFLWC010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28619
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.guided.030"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(<1..416)
                     /locus_tag="L1V17_003059"
     CDS             complement(<1..416)
                     /locus_tag="L1V17_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237727.1"
                     /translation="MKKFAIILTCALLIGTISGCTTSDTSSTSTETSTTTSEKNYPIH
                     FFPVPDGFEAYYHDKKLDVPLSETESTEKILPIEIERNQDDIKLKADLPLLNSTQIDR
                     HENIKVNIEKGALAQLYTEKVEQFFEAGANKDFSKI"
     gene            521..766
                     /locus_tag="L1V17_003060"
     CDS             521..766
                     /locus_tag="L1V17_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBN1237728.1"
                     /translation="MLFLKEEKIIDKENVIGSNIRRVRLEKGIGQTELIRDLQLRKIA
                     ITRETLVKIEGGRQHIKLDQLKAIKDILQVSYEDLLQ"
     gene            922..1773
                     /locus_tag="L1V17_003061"
     CDS             922..1773
                     /locus_tag="L1V17_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HBN1237729.1"
                     /translation="MYKAYELDFTNADLNAFSSSSQSYTHVVNQIDHNQKSINKRIEN
                     LFESENDLVDYYSKDSKILDADEIIKDWFPTIKADIFISHSHADEKLAIRFASWLFEN
                     FGLTAFIDSSVWGYSSDLLKKIDQKYCYKEQTKTYDYDKRNVTTSHVHMMLSTALNNM
                     IDSTECLFFLNTPNSISLSNEITNEQKFTYSPWLYSELTTASIVEKKNPRLESNPQMS
                     TEDVRSIIKHYSSQENLQIKYSLNLSELTYLRKADLKKWALDAVECTKGSNTLDILYK
                     NTIFTNL"
     gene            1806..2480
                     /locus_tag="L1V17_003062"
                     /pseudo
     CDS             1806..2480
                     /locus_tag="L1V17_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287699.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
     gene            2737..2925
                     /locus_tag="L1V17_003063"
                     /pseudo
     CDS             2737..2925
                     /locus_tag="L1V17_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604486.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            2971..3936
                     /locus_tag="L1V17_003064"
     CDS             2971..3936
                     /locus_tag="L1V17_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1237730.1"
                     /translation="MAVFRVEKNKGYTVMSNHHLRNKNLTLKAKGLLSQMLSLPEDWD
                     YTLKGLSYINRESIDAIRTAVWELEKAGYIRREQGRDAKGKMADMVYTIYEQPVLENP
                     VLENPTSDNPVLENPTSDNPASENPTQLNKEVQRTDLSKKEKIITDGQSTHSIPIPSP
                     TPAPMEGEAAATPPERKRTGKDEAVRIYREIILENIEYAYLIQDRSIDREQLDEIVDL
                     MLETVCTARKTIRVAGDDYPAELVKSKYMKLTGEHIRFVLDCLRENTTKVRNIKQYLR
                     AMLFNAPSTISNYYTALVAHDMAQPDWGKPKSGLPDYSCGEGESL"
     gene            3958..4170
                     /locus_tag="L1V17_003065"
     CDS             3958..4170
                     /locus_tag="L1V17_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBN1237731.1"
                     /translation="MKQGALIFDERTDRYDIRFDLADYYGGLHCGECFDVMIGGKWRP
                     TRIEMAENWYLVGIRADDLSGLRVRI"
     gene            4245..4721
                     /locus_tag="L1V17_003066"
     CDS             4245..4721
                     /locus_tag="L1V17_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HBN1237732.1"
                     /translation="MQEEVTQKTIALSMKTGKLTAQVLQAALKKYLQHRAKGKNTLHH
                     GQQSLKQLKKHGADLSNIEITEANIGAFKPCAKKYGVDFTLRKDKTTQPPHYVVIFKA
                     KDADNLDLAFREFTAKTLSKEQRPSIRKVLSAVKQKAAAQTKQRAKEKIKERGLEL"
     gene            4718..6526
                     /locus_tag="L1V17_003067"
     CDS             4718..6526
                     /locus_tag="L1V17_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBN1237733.1"
                     /translation="MKPDVKKLLILNLPYLIFVYLFAKCGEAYRLAAGADLSGKLLHF
                     ADGFAAAFANPLPSLHLFDLCIGIAGAVIVRLVVYCKSKNVKKYRKGMEYGSARWGTA
                     KDIAPYIDPKFENNILLTQTERLTMTGRPKDPKTARNKNVLVIGGSGSGKTRFFVKPN
                     LMQCFPTTDYPTSFVVTDPKGTLVLETGRMFQQAGYRIKILNTINFSKSMKYNPFVYI
                     HSEKDVLKLVNTLISNTKGEGEKSAEDFWVKSERLFYSALIGYIWYEAPAEEMNFSTL
                     LEMINASEAREDDPEFQSPVDLMFERLEQKDPDHFAVRQYKKFLLSAGKTRSSILISC
                     GARLAPFDIREVRELMEDDEMELDTIGDEKTVLYLIMSDTDTTFNFILAMLQSQLINL
                     LCDRADDVYGGRLPVHVRLILDEFANIGQIPNFDKLIATIRSREISASIILQSQSQLK
                     AIYKDAAEIISDNCDSVLFLSGRGKNAKEISDALGKETIDSFNTSENRGSQTSHGLNY
                     QKLGKELMSQDEIAVMDGGKCILQLRGVRPFLSEKFDITKHPRYKYLADADKKNTFDV
                     DRFLTITRRKRQQVVTQDEVFDLYEIDLSDEDAAAE"
     gene            6603..6818
                     /locus_tag="L1V17_003068"
     CDS             6603..6818
                     /locus_tag="L1V17_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016147847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HBN1237734.1"
                     /translation="MAFFNSAVTTLQTIVIGLGGALCVWGGINLLEGYGQDNPGAKSQ
                     GVKQLVAGGGVALIGVTLVPLLSGLLG"
     gene            6910..7773
                     /locus_tag="L1V17_003069"
     CDS             6910..7773
                     /locus_tag="L1V17_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237735.1"
                     /translation="MISEIIEEWIKGILMDGITGNLSGLFDTVNAKVGEIAADVGRTP
                     QAWNSGIFNMLHSLSETVIVPIAGAILALVMCYELIQMITEKNNMHDFDSSMFFRWIF
                     KSAFAILIVTNTWNIVMGVFDATQSVVNQSAGVIIGQTSIDFNTLIPDLESQLEAMSV
                     GALLGLWFQTLVVGLTMNILSICIFLVTYGRMVEIYVVTSLGPIPLATMGNAEWRGMG
                     QGYLKSLLALGFQAFLIMVVVGIYAVLIQNIGSASDISGAIWGCMGYTVLLCFCLFKT
                     GSISKAVFGAH"
     gene            7810..8346
                     /locus_tag="L1V17_003070"
     CDS             7810..8346
                     /locus_tag="L1V17_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methyltransferase"
                     /protein_id="HBN1237736.1"
                     /translation="MSTYNIIYADPPWRYDCKNVQGAAENHYSTMSIDELCALPVERL
                     ASKDCLLFLWATFPMLPEALRLIKAWGFSFKTVAFVWLKQNRKSLTWFYGLGRWTRGN
                     AEICLLATHGKPKRRSASVHQFIISPIEQHSKKPDVTREKIVELAGDLPRVELFARQK
                     TPGWDVWGNEVECDLILT"
     gene            8360..8782
                     /locus_tag="L1V17_003071"
     CDS             8360..8782
                     /locus_tag="L1V17_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBN1237737.1"
                     /translation="MAYVTVPKDLTHVKSKVVFGLTKRQLICFSGALVIGVPLYFLTR
                     DYLTNSAAALLMVFAMLPGFLLAMYERHGQPLEVVIMQIIQCCFIQPKERPYQTDNTY
                     TALVRQYQMEQEVKAIVQKGNPKRNRKNKADPRPAKRN"
     gene            8712..11111
                     /locus_tag="L1V17_003072"
     CDS             8712..11111
                     /locus_tag="L1V17_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBN1237738.1"
                     /translation="MSKKEIPRETEKTKLTRAQRKEIDAVIRKYKGDGRPHTAQQSIP
                     YEVMYPDGVCRVSPGVFSKCIEFADISYQLAQPDTQTAIFEKLCDLYNYVDASIHIQF
                     SFLNRKVDPVQYAKSFEIAPQGDDFDDIRAEYTGILQKQLANGNNGMVKTKYLTFTIE
                     AESVKAARARLKRIGFDLLGYFKSMGAVAHVMDGWERLNLLHGVYHPDGEIFNFDWKW
                     LAPSGLSTKDFIAPSSLCFGNAKTFGMGGKYGAVSFLQILSPELSDDMLADFLNTESG
                     VLVNLHVQAIEQTKAIKTIKRKITDLDAMKIAEQKKAVRSGYDMDILPSDLATYGEDA
                     KKLLTKLQTRNERLFQLTFLVLNVADTKQKLNNDVFQAAGVAQKHNCPLVRLDYQQEQ
                     GLASSLPLGVNQIKIQRSLTTSSVAVFVPFVTQELFQGGAAMYYGINAKSRNMIMLDR
                     KQARCPNALKLGTPGSGKSMSCKSEIVSVFLTTPDDIFISDPEAEYYPLVKRLHGQVI
                     RLSPTSKDFVNPLDINLNYSEDDNPLALKSDFVLSFCELVMGGKNGLEAIEKTVIDRA
                     VRVIYRPYLADPRPENMPILSDLHKALLDQHVPEADRVAQALDLYVSGSLNVFNHRTN
                     VDIGNRLVSFDIKELGKQLKKLGMLIVQDQIWGRVTANRSQGKATWYFADEFHLLLKE
                     EQTAAYSAEIWKRFRKWGGIPTGATQNVKDLLSSPEIENILENSDFITLLNQASGDRK
                     ILAERLNLSTEQQKYIDNSEPGEGLLIFENVVLPFTNPIPHNTQLYKIMTTRLNEVAG
                     V"
     gene            11143..13134
                     /locus_tag="L1V17_003073"
     CDS             11143..13134
                     /locus_tag="L1V17_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBN1237739.1"
                     /translation="MKELKAKAKVTQAMTRDGLTLENQATGEVENISSREAEQDLSAP
                     GPGGTADKLLERADAIHDGHKAKKAAKQAGAVAAEGDAALHRPSARLQLSEEERADPD
                     LQPYIRKSDKRADKLDKARAAIPKKRVPVKETVFDEASGKAKTVLHFDKQDKGPPSLK
                     PNPAGRPVSEVFLFGHGKIHEVEHENVGVEGGHKGEELAERQAGKAIRSTIRHHRLKP
                     YWDAEKAERRLLSANAEYFYQKSLRDNPEIAQAASNPISRFWQKQQIKRQYAKAARTA
                     GQTAGAAAQGAAKTAGASTKAAKAAAKESERAASFVARHWKGALAVLVLGLLMLLIIG
                     GLQSCTAMFGSAGSGITASSYFSEDSDMLAAEDAYAELEAELQDYLDNYEATHDYDEY
                     HFDLDEISHDPYVLISILSALHDGIFTIGEVQGDLSMLFDKQYILTENVVVETRYRTE
                     TDTWTDAEGNTHTDTYQVPYDYYICYVTLENFDLSHVPVYIMDEETLSFYSLYMSTLG
                     NRPDLFSGSQYPNASTLTPPTYYDVPPEALEDATFAAMLKEAEKYIGYPYVWGGSSPS
                     TSFDCSGFISWVINHSGWNVGRLGAQGLYNICTPVSSSQAKPGDLVFFKGTYDTPGVS
                     HVGLYVGNNVMLHCGNPISYTNLTSNYWQSHFYSYGRLP"
     gene            13157..13408
                     /locus_tag="L1V17_003074"
     CDS             13157..13408
                     /locus_tag="L1V17_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HBN1237740.1"
                     /translation="MATKLDRIEKDIQKTKSKIAEFQKQLRELETQKTEQENLQIIQL
                     VRGMNMKPEEFAAFLRSGAMQAAPAATPYHEQEDNAHEE"
     gene            13398..14627
                     /locus_tag="L1V17_003075"
     CDS             13398..14627
                     /locus_tag="L1V17_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HBN1237741.1"
                     /translation="MKNKTRRISRILPALLAVMLCVTAFPVTALAGGNDPAPAPLPEA
                     TTEPATGGLEPETDETGTATDGTETEAEKDTGPLTGKDITDLFSALFGSKVSIAATDD
                     GIQITTGTDKKEPEQTGTVTTNGGRLNVRTGAGLDKTAFTQLPNGTTVEVVGTDGDWI
                     KILLPERIGYVHSDYMTVSEKEVAATGEGGFSLSIDPEEIASLLELFNGGGASAALSP
                     DGNLSLIDDIGSAAKNGKQFITVETKNGNVFYLIIDRDDEGKETVHFLNQVDEADLLT
                     LMEDGETVTPAAVCSCTTKCKAGAVNTNCPVCKTNLTECSGPEPQEPQPEEPEAPEEE
                     PKGGAGGLIVFLLVALAGGGAALYYFKFKKPKAETTGSDDLGEYDFGEDEDLEDEEPE
                     TEFDPEADFVSEQEDEE"
     gene            14624..16705
                     /locus_tag="L1V17_003076"
     CDS             14624..16705
                     /locus_tag="L1V17_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HBN1237742.1"
                     /translation="MTYKLVIAEKPSVARSIAGVIGATEKHDGYLEGNGYLVSWCIGH
                     LVSFADAGRYDERFKKWRYEDLPILPETWQYIVPDDKKQQFDVLCSLMQRPDVTGLVC
                     ATDAGREGELIFRFVYQMAGCQKPFERLWISSMEDSAIKDGFAHLKPGGDYDPLYQSA
                     LCRAKADWLIGINATRLFSVLYHKNLTVGRVQTPTLKMLVDRDAKITDFKKEKYHIVH
                     ITAGGADAVSSRFSDAAEANTVKAACAKAQAVCVSVTREKKTEQPPKLYDLTTLQREA
                     NRLFGYTAKQTLDYAQALYLKKLLTYPRTDSQYLTDDMLPAVESLVSGLWELVPFAKG
                     LNLSPQFDRILNSKKVSDHHAIIPTAEFVKQGFGTLAESEKKLLSLICCKLLCAVAGP
                     HIYEAVTATFTCAGQEFTAKGKTVLSPGWKEIERRFRSSLKTDADEDAEAVRELPELC
                     EGQTFADVAASVTEHFTTPPKPYTEDTLLSAMERAGAEDMPEDAERKGLGTPATRAAI
                     LEKLVQMGFVQRKGKQLIPTKDGINLAVVLPEALTSPQLTAEWENRLTEIAKGQADPD
                     EFMDGIETQARELVQTYSCISEEKQKLFQAERVPIGTCPRCGEAVYEGKKNYYCGNRA
                     CQFVMWKNDRFFEERKKAFTPKIAAALLKTGKVKVKGLYSVKTGKTYDGTVLLADTGG
                     KYVNYRIEHRS"
     gene            16854..20774
                     /locus_tag="L1V17_003077"
     CDS             16854..20774
                     /locus_tag="L1V17_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
                     /protein_id="HBN1237743.1"
                     /translation="MNEVFSIQVHNRQFLEQGKQGVWLDLPTTTETLQAALRDVGITA
                     DNPQDFFINGYSCPEDRHLAIPYDMVLAADVDELNFLAARLGQLDAAEIAELNAALQN
                     PRGGFENIGQIIDYTENVDYYVHLPDVRGDGQLGDYYLNRSGMVDMPEEWKAGIDTAQ
                     FGRHIAQQEQGVFTQYGYLVRSGDEWQRVHEGQPVPEEYRVMHYPQPEADREEPQAQQ
                     PEASESPDKAPPPVIPIMLDGMNSKERMKVITDRLETGVQELFESSRYMAYLSAMSKM
                     HDYSLNNTLLIAMQGGSIVAGYNRWQDEFDRHVKRGEKGIKILAPAPFKVKQQMEKTD
                     PATQQPVIGADGKPVTEEQEVTVPAFKVVTVFDISQTEGKDFPMPYISELTGDVQQYQ
                     DFFAALERTSPYPISIEPISDGAKGRCFYAKQRIAINEGMSELQTLKTAIHEIAHAKL
                     HAIDREAPAEEQAARPDRSTREVQAESVAYTVCQYYGLDTSDYSFGYVADWSSGRELS
                     ELKASLETIRATASELITEIDGHFAQLQQEREARQEQEAVTVDVTPEAAAPAQAEEEQ
                     APALDPAAEPLVTVLWSESPQLKDGQQMPLHEADALFARLDAAYPAEAGYDKTAFRID
                     CIFQGEPDSYEGRQDFGDRDGSLIEHIQSYHQFYAQDENWKKHVIATTGIEGWEQDKA
                     HRDMLLGEFVPYMKLHCSLAQMEQTAQGRLQSGETLTPEETAYLGALLSYVQECRPML
                     NQGQYQLPEPPKLADFDQSLQDYKAQVQAEIAQEAAAAGMTVEEYAAAGYEAPQQDTF
                     SIYQLRGGEETRDYRFEPYERLQAAGLAVDSANYDLVYTAPLDKSTSLEDIYRTFNID
                     HPADFRGHSLSVSDVVVLHQNGQDTAHYVDSFGYMEVPEFLRENPLRTAELSTEQNEN
                     MIDGIINNTPPEPQPEEPEQLSFEDVAVASGQTQEEPPEAAPPQTAVRYYPINEGAAR
                     RAKEAMSFSDYRPGSATAEYRHYVDQAVEIAERQKKRVEPEYHEKIDSLLDTYARKLA
                     ENMNKGYEITARVPSVLIAGPSNFPVRAKEKQNAASDRNMEEFQYIQGLLDKIRSTGM
                     GGISADDPQAVSKLEKKLEKLEASQELMKAVNAYYRKHGTLDGCPHLIERGIENLKAD
                     MASGWHYEKKPFQSWQLSNNNAEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRVA
                     NRLQIFFEGKPDAAVRDELKSNGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGEK
                     PSALQLAARREKEKPSIRAQLNAAKTEQAKQPPAREKSKGLEVE"
     gene            20775..21719
                     /locus_tag="L1V17_003078"
     CDS             20775..21719
                     /locus_tag="L1V17_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237744.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            21723..21926
                     /locus_tag="L1V17_003079"
     CDS             21723..21926
                     /locus_tag="L1V17_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HBN1237745.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMPVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(22226..22462)
                     /locus_tag="L1V17_003080"
     CDS             complement(22226..22462)
                     /locus_tag="L1V17_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBN1237746.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(22645..23031)
                     /locus_tag="L1V17_003081"
     CDS             complement(22645..23031)
                     /locus_tag="L1V17_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HBN1237747.1"
                     /translation="MDARAMSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECI
                     CVQSISYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAA
                     CSKRMRRRKEAERQRKRYWKPTHLEL"
     gene            complement(23013..24341)
                     /locus_tag="L1V17_003082"
     CDS             complement(23013..24341)
                     /locus_tag="L1V17_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBN1237748.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            complement(24302..24631)
                     /gene="mobC"
                     /locus_tag="L1V17_003083"
     CDS             complement(24302..24631)
                     /gene="mobC"
                     /locus_tag="L1V17_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBN1237749.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            complement(24889..25259)
                     /locus_tag="L1V17_003084"
                     /pseudo
     CDS             complement(24889..25259)
                     /locus_tag="L1V17_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            25404..25589
                     /locus_tag="L1V17_003085"
     CDS             25404..25589
                     /locus_tag="L1V17_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBN1237750.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            25747..25914
                     /locus_tag="L1V17_003086"
     CDS             25747..25914
                     /locus_tag="L1V17_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237751.1"
                     /translation="MKKRNFIMTEMENARNKDEEAAAVSAVYGRIEKAGIWILYGEVS
                     RHWITAGLMRL"
     gene            26532..27191
                     /gene="vanR"
                     /locus_tag="L1V17_003087"
     CDS             26532..27191
                     /gene="vanR"
                     /locus_tag="L1V17_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance response
                     regulator transcription factor VanR"
                     /protein_id="HBN1237752.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            27194..28555
                     /gene="vanS"
                     /locus_tag="L1V17_003088"
     CDS             27194..28555
                     /gene="vanS"
                     /locus_tag="L1V17_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBN1237753.1"
                     /translation="MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPNFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQARSRKSGRSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLT
                     STL"
BASE COUNT         7363 a         7297 c         7599 g         6360 t
ORIGIN      
        1 cttatttttg aaaagtcttt attggcacca gcctcaaaaa attgttcaac tttttcagta
       61 taaagttgtg ctaacgctcc tttttcaata ttaactttaa tattttcatg tctatcaatt
      121 tgtgtgctgt tcagtaaggg aagatcagct tttagtttta tatcgtcttg atttctttca
      181 atttcaattg gcaaaatctt ttcagtagat tcagtttctg ataaaggaac atctagtttt
      241 ttatcatgat aataagcttc aaatccatct ggaaccggaa aaaaatgtat tgggtaattc
      301 ttttctgagg ttgttgtact agtttccgta cttgtagaac ttgtgtcaga agtggtacac
      361 ccgcttatag ttccgatgag taaagcgcaa gttagaatga ttgcaaattt cttcaaaaaa
      421 attcctcctt aaaattgaat atggactaat actagtccca ttgtagcata ccgaatcttt
      481 aagattaata agaaaaagga ctaattttag tccaaaaggt gtgctattct tgaaagagga
      541 aaaaattatt gataaagaaa atgtaatcgg tagcaatatt agacgagtcc gattagaaaa
      601 aggaattggt caaaccgagc tgattagaga cctacagctt cgtaaaattg ctataactag
      661 ggaaacgttg gttaagattg aaggtggccg ccaacacatt aagttggatc aattgaaagc
      721 catcaaagat attctacagg tgtcttatga agatttgctt caatgactac ttgtagtcat
      781 ttcgtttgaa attattatgt tacaccctta tgtgtcacga agaaatactg gtataataat
      841 gaatgggata tgtaacgata gggtatactg ttatgttgcc taataaattg tggatcaaaa
      901 tacaagaatg gagggatatc cttgtataag gcatatgaat tggattttac aaatgctgac
      961 ttaaatgcat tctcctcaag ctcgcaatca tatacacatg tagtaaatca aatagatcac
     1021 aaccaaaaat ctattaacaa gagaatagaa aatctatttg aaagtgaaaa tgatttagtt
     1081 gattattatt ctaaggacag caaaattcta gatgcagacg aaattattaa agattggttt
     1141 ccaactataa aagcagatat ttttatatct cactctcatg ctgatgaaaa attagctata
     1201 cgttttgcat catggctatt tgaaaatttt ggtcttactg catttattga ttcttcggtt
     1261 tggggataca gttctgattt attaaaaaaa atagaccaaa aatattgcta taaggaacaa
     1321 acaaaaacat atgattatga taaaagaaat gtaacaacta gtcatgttca tatgatgctt
     1381 tctacagctt taaataatat gattgatagt acagaatgtc tgttttttct taatacacct
     1441 aattcaatta gtttgagcaa tgaaatcact aatgaacaga aatttacgta ttcgccatgg
     1501 ctatatagcg aactgacgac agcttcaata gtggaaaaaa agaatccacg attggaaagt
     1561 aatcctcaaa tgagcaccga ggatgttaga agcattataa agcactattc ttcgcaagaa
     1621 aatctgcaaa taaaatattc tttaaattta agtgaattaa cttatttacg aaaagctgat
     1681 ttgaaaaaat gggctttaga tgctgtggaa tgcactaaag gaagtaatac attagatatt
     1741 ttatataaaa acaccatttt cactaatctc taatcaattt actgaatcga aaggaaccgg
     1801 gtagaatgga taagaaagtt ttaataaaga ggttctctga agctattgaa aaaggaaatg
     1861 cagcaatatt tgcaggtgca ggattatcga tgtcacaagg atatgtaagt tggccggaac
     1921 tacttaatga tcctgcaaca gaaatcgggt tggattctaa aaaagaaaca gacttagtta
     1981 ctctggctca atattataaa aatgaaaatg gtggatcaag aggaattttg aatcagatac
     2041 ttatggataa ttttggtgaa gaattagaaa tatctgaaaa tcatcgaata ctagcaagtt
     2101 tacctattga aacttattgg acaactaatt atgatcatct aatagaaaaa tcaatccgag
     2161 aagcttataa aaaccctcag gttaagaaaa attatactca gttagcaaca actaatccaa
     2221 atgtggatac aattgtttat aaaatgcatg gtgatataga tgatgtcagt tcgacagtaa
     2281 taacaagaga tgattatgaa aaatatgatg attcgtacgc gttatttaaa gaaactttaa
     2341 aaggagattt gttaacaaaa acttttctct ttttaggatt tagttttaca gaccctaatt
     2401 tagaaagaat tttatcagat ataagatggg ttttgagaga aaaccaaaga cctcattatt
     2461 gtataatgag aaaaatatta tagaaaaaat tttaggttat cgctgaaagc cccggaaata
     2521 cgggcatttc gcaggatatg agaactcaat ttactaccaa tttactactt tcggattgag
     2581 ccgcatatat gctgaaccat actgctaata cccgccaccc caaatacggc acatcataaa
     2641 ttgaatacga caccgtaaac gcggcgttcc tctttcccgt catgggagaa caggacgccg
     2701 cttttttatg cccaaataga gaaaggaggc gacgccatgc tatttacttc cggccctgac
     2761 cgggcgtttg aacggctgat gcaggaaaag cccggtttcg atcactacga cggcggcggg
     2821 gcggacgcgc cggaggattg cggcacctgc cgattttacc gcccggattg gaaatatcaa
     2881 ttctgccagt ttgcagagtg tccctatcag ccgggcaagc tgaccgacta tgcagcggtc
     2941 aaattcacag tgaaaggagc gaacaacgct atggcagttt tccgtgtgga aaagaacaaa
     3001 ggctatacgg tgatgtcaaa tcaccacctg cggaataaga acctgacctt aaaggccaag
     3061 ggcctgctgt cgcagatgtt gtccttgccg gaggattggg actataccct aaaaggactg
     3121 tcctatatca accgggaaag catcgacgcg atcaggacag cggtatggga gcttgaaaaa
     3181 gctggatata tccggcgtga gcagggccgt gacgcaaaag gcaaaatggc cgatatggtc
     3241 tataccatct acgaacagcc ggtattggaa aacccggtat tggaaaatcc aacatcggat
     3301 aacccggtgt tggaaaatcc gacatcggat aatccggcgt cggaaaatcc aacgcaatta
     3361 aataaagaag tacaaagaac tgacttatca aaaaaagaaa aaataattac agatggacaa
     3421 agtacccatt ccattcctat cccatccccg acccctgccc ctatggaggg cgaggcagcg
     3481 gctacgccgc cggaacggaa aaggacagga aaggatgagg ctgtacggat ttatcgggaa
     3541 atcattttgg agaacatcga gtatgcctat ctcattcagg acaggagcat tgaccgtgaa
     3601 cagcttgacg aaatcgtaga cctgatgctg gaaaccgtct gcaccgcccg aaagacaatc
     3661 cgtgtcgccg gggacgacta ccctgccgag ctggtgaaat ccaagtacat gaagctgacc
     3721 ggcgaacata tccgctttgt ccttgactgt ctgcgggaga acacaacgaa agtccgcaat
     3781 atcaaacaat acctgcgggc tatgctgttc aacgccccca gcaccatttc caactactac
     3841 acggcccttg tcgcgcacga catggcacag cccgattggg gaaagcctaa atccggcctg
     3901 ccggactatt cctgcggcga gggcgaaagc ctgtaacgag aaaaggagga cgaccctatg
     3961 aagcagggcg cattgatttt tgacgagcga acagaccgtt acgacatccg ctttgatctg
     4021 gccgactatt acggcggcct gcattgcggg gagtgtttcg acgtgatgat cggcggcaaa
     4081 tggaggccca cccgcattga aatggccgaa aactggtatc ttgtcggcat ccgggccgac
     4141 gacctttccg gcctgcgggt gcggatttga cctatatcta cctgcggcgt ctggtggttc
     4201 cgccttagac gccgcttttg actttctgac aaggagggat gcgattgcag gaagaagtta
     4261 ctcaaaagac cattgccctg tccatgaaaa cgggcaagct cacggctcaa gtgctgcaag
     4321 cggcgctgaa aaagtacctg caacaccggg ccaagggcaa aaacacgctg caccacggcc
     4381 agcagagcct aaagcagctt aaaaagcatg gggctgatct ctccaacatt gagatcaccg
     4441 aggccaacat tggagcgttc aagccatgcg ccaagaaata cggcgtggat tttaccttac
     4501 gaaaagataa gaccacccag ccgccccact acgttgtgat tttcaaggcc aaggatgcag
     4561 ataaccttga tctggcgttt cgggagttta ccgccaagac gctttccaag gagcagcggc
     4621 cctctatccg caaggttttg tccgctgtga agcaaaaggc ggcggcccag accaagcagc
     4681 gggccaagga gaaaatcaag gaaagggggc tggaactgtg aagcctgacg taaagaaatt
     4741 gctgatcctg aacctcccgt atctgatttt tgtgtacctg tttgcgaaat gcggggaggc
     4801 gtaccggctg gccgctggtg ctgacctgtc ggggaagctc ctgcattttg cggatggttt
     4861 tgcggcggct tttgccaacc cgctgccaag cctgcacctg tttgacctgt gtatcggtat
     4921 cgccggtgcc gtgatcgtgc ggctggtggt gtactgcaag agcaagaacg tgaagaaata
     4981 ccgcaaaggc atggagtatg gcagcgcccg ctgggggacg gccaaagaca tagcgcctta
     5041 catcgacccc aagtttgaaa ataatatcct gctcacccaa acggaacggc ttaccatgac
     5101 cggcaggccc aaagacccca agacagcgcg gaataaaaac gtgctggtga tcggtggcag
     5161 cggttcaggg aaaacgagat ttttcgtgaa acccaacctg atgcaatgct ttccgaccac
     5221 ggactatccg acttcgtttg tggtgacaga tccgaaaggc actttggttc tggaaaccgg
     5281 caggatgttc cagcaggcgg gctaccgcat taaaatcctg aataccatta acttttccaa
     5341 gtccatgaag tacaacccct ttgtctacat ccattcggaa aaggacgtgc taaagctggt
     5401 aaataccctg atttccaaca ccaagggcga gggggaaaag tcagcggagg atttttgggt
     5461 gaagtcggaa cggttgtttt attcggccct gatcggctat atctggtacg aggccccagc
     5521 ggaggaaatg aacttctcaa cgctgctgga aatgataaac gccagtgaag cccgcgagga
     5581 cgacccggag tttcaaagcc ccgtcgatct catgtttgag cgtttggagc agaaagaccc
     5641 cgaccatttt gcggtgcgcc agtacaagaa attcctgctg tccgcaggca agacccgttc
     5701 ttccatcctg atttcatgcg gtgccagact tgcgcccttt gacatccggg aggtacgcga
     5761 gctgatggag gacgacgaaa tggagctgga caccatcggg gacgaaaaga cggtgctgta
     5821 tctcattatg agcgatacgg acacgacctt taatttcatt ctggctatgc tccaaagcca
     5881 gctaatcaac ctgctttgtg accgggctga tgatgtgtac ggcgggcggc tgcctgtcca
     5941 tgtacgcctg attttggatg aatttgccaa cattggccaa atacccaatt tcgataaact
     6001 cattgccacc attcgaagcc gtgaaatatc ggcctctatt attttgcaga gccagtcgca
     6061 gctaaaagcg atttacaagg acgccgccga gatcatttcg gataactgcg atagtgtgct
     6121 tttccttagt gggcgcggca aaaatgccaa ggagatttcc gatgcgctgg ggaaagaaac
     6181 gattgacagt ttcaacacca gcgagaaccg gggaagccaa acgtcccacg gattgaacta
     6241 tcaaaaatta ggaaaggagt tgatgtccca agacgaaatt gccgtgatgg acggcggcaa
     6301 gtgtatcttg cagctacggg gtgtgcgccc gtttttatcg gagaaattcg atattaccaa
     6361 gcatccccgg tacaaatacc ttgccgacgc cgacaagaag aatacctttg acgtggacag
     6421 atttttgact atcacgcgcc ggaaacggca gcaagtggta acgcaggatg aagtattcga
     6481 cctgtatgaa atcgacctgt cggacgagga cgccgccgct gaataaacag cggctttttt
     6541 cattccaaca acaaaatcaa aaaatcatta tgagccggaa accggcagaa agaggtaaat
     6601 ttatggcatt ttttaattcc gcagttacta ctttgcagac tatcgtgatc ggactgggcg
     6661 gcgctctgtg cgtatggggc ggcatcaatc tgttggaggg atacgggcag gacaatccgg
     6721 gggcaaaatc gcagggtgtc aagcagcttg tcgctggcgg cggcgtggcc ctgatcggtg
     6781 tcactctggt tcccctgctg tccgggctgc tgggctgatc ctggcctttg tccctgtcca
     6841 aacccttaac taatcgcctc cgcgtcctcc cggccagacc gggagggcgc gggaaaggag
     6901 gtgctacccg tgattagtga aatcattgaa gaatggataa aaggcatcct catggacggt
     6961 atcacgggca acctgtccgg gctgttcgat acggtaaatg ccaaagtcgg agaaatcgcc
     7021 gccgacgtgg gacgaacccc gcaggcatgg aacagcggta ttttcaatat gctgcacagc
     7081 ctgtcggaaa ccgtgatcgt ccccatagcc ggggccatac tcgcccttgt catgtgctat
     7141 gagcttatcc agatgataac ggaaaagaac aatatgcacg actttgacag ctccatgttc
     7201 ttccgctgga tattcaaatc cgcgtttgca atcctgatcg taacgaacac atggaacatc
     7261 gtcatgggcg tattcgacgc cacccaaagc gtcgtcaatc aaagcgccgg tgtgattatc
     7321 gggcagacat ccattgattt taacaccctg ataccagacc ttgaaagcca attggaggct
     7381 atgagcgtgg gcgctctttt ggggctgtgg ttccaaaccc ttgttgtggg cctcaccatg
     7441 aatatccttt ccatctgcat tttccttgtg acctatggcc gcatggtgga aatctatgtt
     7501 gtcacgtcgc tggggcctat cccccttgcc acaatgggca acgcggaatg gcgcggcatg
     7561 ggccaagggt atctgaaatc cctgctggcg ctgggcttcc aagccttttt aatcatggtt
     7621 gtggtgggta tctacgcggt gctgatacag aatatcggtt ccgcttccga catatccggc
     7681 gcaatctggg gctgtatggg ctatacggtg ctgctgtgct tctgcctgtt caagaccggc
     7741 agtatatcaa aggccgtatt cggggcgcat tgatcccaaa atccaagcat acacaggagg
     7801 aacttgttta tttcaacgta caacatcatt tacgctgacc cgccgtggcg gtatgactgc
     7861 aaaaacgtac agggcgcagc ggaaaatcac tattccacca tgagcattga cgagctgtgc
     7921 gccctgccgg tggaacggct ggcgtccaaa gactgcctgc tgtttttgtg ggccacattc
     7981 cccatgctgc cggaagctct gcggttaatc aaagcgtggg gcttttcatt caagaccgtg
     8041 gcttttgtat ggctgaaaca gaaccgtaaa agccttacat ggttttacgg gctgggccgc
     8101 tggacaaggg gaaacgcgga aatctgcctg ctggcaacac acggcaagcc gaagcgtcgt
     8161 tctgcctctg tccatcagtt tattatcagc ccgattgaac aacacagcaa aaagccggat
     8221 gtgacccgtg aaaaaatcgt agagctggcg ggcgatttgc cccgcgtgga gctgtttgcc
     8281 agacagaaaa cccccggctg ggacgtgtgg gggaacgagg tggaatgtga ccttatcctg
     8341 acgtgaaagg aggtgccaaa tggcttatgt aaccgtcccc aaggacttaa cccatgtgaa
     8401 aagcaaggtt gtgtttgggc ttaccaaacg gcaactgatc tgtttttccg gggcgctggt
     8461 gatcggcgtc cccttatatt ttctcacccg tgactatctt accaacagcg cggcggccct
     8521 gctcatggta tttgccatgc tgccgggctt tttgcttgcc atgtacgagc gtcacggcca
     8581 gccccttgaa gtggtgatta tgcagatcat ccagtgctgc ttcatccagc caaaggagcg
     8641 tccctatcag accgacaaca cctacaccgc ccttgtgcgg caataccaga tggaacagga
     8701 ggtaaaggcc attgtccaaa aaggaaatcc caagagaaac cgaaaaaaca aagctgaccc
     8761 gcgcccagcg aaaagaaatt gacgcggtaa tccgtaaata taagggcgac ggcaggcccc
     8821 acacggcgca gcagagcatc ccctacgagg tcatgtaccc ggacggcgtg tgccgggtat
     8881 cgcccggcgt cttttccaag tgcattgagt ttgcggacat cagctatcag cttgcccagc
     8941 cggacacgca gacggctatc tttgaaaaac tgtgcgacct gtataactat gtggacgcct
     9001 ccattcatat ccagttttct ttcctcaatc ggaaagttga cccggtgcag tacgccaaga
     9061 gctttgagat cgcgccgcag ggggacgact tcgacgacat ccgggccgag tacaccggca
     9121 ttctgcaaaa gcagcttgca aacggcaaca acggcatggt aaagaccaaa tacctgacat
     9181 tcaccatcga ggccgaaagc gtgaaagcgg cgcgagccag attgaagcgc atcggctttg
     9241 acctgttagg ctatttcaag agcatggggg ccgtagccca tgtgatggac ggctgggaac
     9301 ggctgaacct gctgcatggc gtgtaccacc cggacggcga gatattcaat tttgactgga
     9361 agtggctggc cccgtccggc ctctccacca aggattttat tgccccgtcc tccctgtgct
     9421 tcggcaatgc aaagacattc ggcatgggcg gcaaatacgg cgcggtaagt ttcctgcaaa
     9481 tcctgtcccc ggagctgtcg gacgatatgc tggccgactt cctcaatacg gaaagcggtg
     9541 ttttagtcaa tctccatgtg caggccattg aacagaccaa ggcgatcaag accatcaagc
     9601 gcaaaattac cgaccttgac gctatgaaga ttgcggagca gaaaaaggcc gtccgcagcg
     9661 gttacgatat ggacattctt cccagcgacc ttgccaccta cggcgaggac gccaagaagc
     9721 tgctgacaaa gttgcagacc cgcaatgaac ggctgttcca gttgacgttc cttgtcctca
     9781 acgtggccga caccaagcaa aagctgaata acgacgtgtt ccaagccgca ggcgtggccc
     9841 aaaagcataa ctgtcccctt gtccggctgg actaccagca ggaacagggc cttgcaagca
     9901 gcctgccgct gggcgtcaat cagatcaaga tacagcgcag ccttacgact tccagcgtgg
     9961 ccgtgttcgt cccctttgtg acgcaggagc tttttcaggg cggcgcggcc atgtattacg
    10021 gcatcaacgc caagtcccgc aacatgatta tgctggacag gaagcaggcc cgttgcccca
    10081 atgccttgaa gctcggcacc cccggcagcg gcaaatccat gagctgtaaa tccgagatcg
    10141 tcagtgtgtt cttaacgacg cctgacgata tttttatttc agacccggag gccgaatatt
    10201 acccccttgt caaacggctc cacggacagg taatccggct gtcgcctacc agcaaggact
    10261 ttgtgaaccc gctggacatc aacctgaatt attcggagga cgataacccg ctggccctga
    10321 aatccgactt tgtgctgtcg ttctgtgagc ttgtcatggg cggcaagaac gggctggaag
    10381 ccattgaaaa gaccgtgata gaccgggctg tgcgcgtgat ctaccggccc tatctggcag
    10441 acccccgccc ggagaatatg ccgatcctgt ccgacctcca caaagcgttg ttagatcagc
    10501 atgtcccgga ggctgaccgg gtggcgcagg cccttgacct gtatgtgtcc ggctccctga
    10561 acgtatttaa ccaccgtacc aacgtggaca tcggcaaccg gcttgtgtcc tttgacatta
    10621 aggagctggg caagcagctc aaaaagctgg ggatgctcat tgtccaagac cagatatggg
    10681 ggcgcgtcac ggccaaccga agccaaggaa aggccacatg gtattttgcc gacgagttcc
    10741 atttgctttt gaaagaggaa cagacggcgg cctattctgc ggagatttgg aagcggttta
    10801 ggaaatgggg cggcattcca acaggtgcca cccagaacgt caaagacctg ctttcctccc
    10861 cggaaattga aaatatcctt gaaaacagcg acttcattac gctgctcaat caggcgtccg
    10921 gggatagaaa aatccttgcg gaacgcttga atttgtccac cgaacagcag aagtacatcg
    10981 acaattccga acccggcgag ggccttttga tctttgaaaa cgtggtgctg ccctttacca
    11041 accccatccc gcacaacacc cagctttaca agattatgac gacccgctta aacgaggtgg
    11101 cgggagtatg acccggcgac gccacaaagg aggtgaacca ccatgaaaga gctgaaagcc
    11161 aaggcgaaag tgacgcaggc catgacccgc gacgggctga cgctggaaaa tcaggccacc
    11221 ggcgaggtgg agaacatttc cagccgggag gccgaacagg atttgtccgc gccggggccg
    11281 ggcggcaccg ccgataagct gctggaacgg gccgacgcca tccatgacgg ccataaggcc
    11341 aagaaagccg cgaagcaggc cggggctgtg gccgccgagg gggacgctgc cctgcaccgg
    11401 ccatccgccc ggctccaact gtcggaggaa gaacgggccg acccggattt acagccctat
    11461 atccgaaaat cggacaaacg ggccgataag ctggataagg cccgcgccgc catccccaag
    11521 aagcgcgtcc cggtcaagga aaccgtcttt gacgaggcaa gcggcaaagc aaagaccgtc
    11581 ctgcactttg acaaacagga caaggggcct ccctccctga aacccaatcc ggcaggccgt
    11641 cctgtttccg aggtttttct attcggccac gggaaaatcc atgaagtcga gcatgaaaac
    11701 gtgggtgtgg agggcggcca taagggggag gaacttgccg agcggcaggc cggaaaagcc
    11761 atccgcagca ccatccggca ccacaggctg aaaccctact gggacgcgga aaaggccgag
    11821 cgcaggctat tgtctgccaa cgcggagtat ttctaccaga aatctttgcg ggataacccg
    11881 gagatcgcac aggcggccag caaccccatt tcccggttct ggcagaaaca gcagatcaag
    11941 cgccagtacg ccaaggccgc ccggacagcg ggccagaccg caggcgcggc ggcacagggc
    12001 gcggccaaga cagccggggc ctccacgaaa gcggccaagg ccgcagccaa agaaagtgaa
    12061 cgggcggcct cctttgtggc ccgccactgg aaaggggcgc tggccgtcct tgtgttgggg
    12121 cttttgatgc tgcttatcat cggcggctta cagtcctgca ccgccatgtt cggcagcgcc
    12181 ggaagcggca tcacggcgtc ctcttacttt tccgaggata gcgatatgtt ggccgccgag
    12241 gacgcctacg cggagctgga agccgagctg caagactatc tggacaacta cgaggccacc
    12301 catgactatg acgaatacca ttttgacctt gacgagatca gccatgaccc ctatgtgctg
    12361 atttccattc tgtcggcgct ccatgacggg atatttacca tcggggaggt acagggtgat
    12421 ttgtccatgc tctttgacaa gcaatatatc ctgacagaaa acgtcgtggt agaaacccgt
    12481 taccgcaccg aaaccgatac atggacggac gcggagggca acacccatac agacacctac
    12541 caagtgccgt atgactatta catctgctac gtcacgctgg aaaacttcga cctgtcccat
    12601 gtgccagtct atatcatgga cgaggaaacg ctaagtttct attccctgta tatgtccacg
    12661 ctaggaaacc ggcctgatct gttttccggc agccagtacc ccaacgcctc caccctgacg
    12721 ccgccgacct actacgacgt acccccggag gctttggagg atgccacctt tgccgccatg
    12781 ctcaaagagg cggaaaaata tatcggttat ccctatgtgt ggggcggcag ctctcccagc
    12841 accagctttg attgcagcgg cttcatttcg tgggtaatca atcatagtgg atggaacgtg
    12901 ggacggctgg gggcgcaggg cctatataac atctgcaccc ctgtttccag ttcgcaggcc
    12961 aagcccggcg accttgtatt tttcaaggga acctacgaca cccccggcgt gtcccacgtc
    13021 ggcctgtatg tgggcaacaa tgtgatgctg cattgcggga acccgatttc ctacacgaac
    13081 cttacttcaa actactggca atcccatttt tacagttacg ggcgtttacc ttaacgccag
    13141 aaaggagctt tcaattatgg caaccaaact tgaccgcatc gaaaaggaca tccagaaaac
    13201 caagtctaag atcgcggagt ttcagaaaca gcttcgggag ctggaaacgc agaaaaccga
    13261 acaggagaat ttgcagatca tccagcttgt gcgcggcatg aacatgaagc cggaggaatt
    13321 tgccgcgttc ttacgcagcg gcgcaatgca ggccgcccct gccgcaaccc cttaccatga
    13381 acaggaggac aatgcccatg aagaataaga ccagacggat ttcccgtatt ctccccgcac
    13441 ttctggccgt gatgctctgc gtcacggcct ttcccgttac cgcccttgca ggcggcaatg
    13501 acccggcacc ggccccgctg ccggaggcta caaccgaacc cgctacgggc ggtttggagc
    13561 ctgaaacaga cgaaaccggc accgccacgg acgggacaga aaccgaggcc gaaaaagata
    13621 ccggccctct gaccggcaag gacatcaccg acctgttttc cgcgctgttc ggttccaagg
    13681 tgagcattgc cgccacggac gacggcatcc agatcaccac cggcaccgac aaaaaagaac
    13741 ctgaacagac cggcaccgtc accaccaacg gcggcaggct gaatgtccgc accggcgcgg
    13801 ggcttgacaa gaccgcgttc acccagcttc ccaatgggac gacggttgag gtagtcggca
    13861 cagacggcga ctggattaaa attctcttgc cggagcgcat cggctatgtc cattccgact
    13921 atatgaccgt cagcgaaaag gaagtagcgg ctaccggcga gggcggtttt tccctctcca
    13981 ttgacccgga ggaaattgct tctctgctgg aactgttcaa tggcggcggg gccagcgccg
    14041 ccctgtcccc ggacgggaac ctgtcactga ttgacgacat cggcagcgcc gcgaaaaatg
    14101 gcaagcagtt tatcaccgtg gaaaccaaaa acggcaatgt gttttatctg attattgacc
    14161 gggacgacga gggaaaagaa actgtccatt tcttaaatca ggtggatgaa gccgatctgc
    14221 tgacgctgat ggaggacggg gaaaccgtca cccccgctgc tgtctgctcc tgtaccacga
    14281 aatgcaaggc cggggctgtg aacacgaatt gcccggtatg taaaaccaac ctgaccgagt
    14341 gcagcggccc ggagccgcag gaaccccagc cggaggaacc cgaagccccg gaggaagaac
    14401 ccaagggcgg cgcgggcggc ctgatcgtgt tcctgctggt ggcgctggcg ggcggcggtg
    14461 cggcccttta ctatttcaag ttcaaaaagc ccaaggctga aaccaccggc agcgacgatt
    14521 tgggcgagta tgattttggg gaggacgagg atttggagga cgaggaaccc gaaaccgagt
    14581 ttgacccgga agctgatttt gtgagtgaac aggaggacga ggaatgacat ataaacttgt
    14641 aatcgcggaa aaacccagcg tggcccgcag cattgcgggc gtgatcgggg ccacggagaa
    14701 acacgacggc tatttggagg ggaacggcta tctggtgagc tggtgcatcg gacatctggt
    14761 gtcctttgcc gacgccggac gctatgacga gcgtttcaaa aaatggcgct atgaggattt
    14821 gcccattctc ccggaaacat ggcagtacat cgtccccgac gacaagaaac agcagtttga
    14881 cgttctctgt tcgctgatgc agcgccccga cgtgaccggc cttgtgtgcg ccaccgacgc
    14941 cgggcgcgag ggggaattga ttttccgttt cgtctaccag atggcgggat gccaaaagcc
    15001 ctttgagcgc ctttggattt cctctatgga ggacagtgct attaaggacg gctttgccca
    15061 cctgaaaccg ggcggcgact atgatccgct gtatcaatcg gccctgtgcc gggccaaggc
    15121 cgactggctg atcggcatta acgccacccg gcttttttcc gtcctgtacc acaagaacct
    15181 gactgtgggc cgcgtccaga cgccgacctt aaaaatgctg gtggacaggg acgccaagat
    15241 taccgatttc aagaaagaga aatatcacat cgtccatatc acggcgggcg gcgcggacgc
    15301 ggtaagcagc cgcttttccg acgctgccga ggcaaacacc gtcaaggcgg cttgtgcaaa
    15361 agcgcaggcc gtttgcgttt ccgtgacgcg ggagaaaaag acggaacagc cgcccaagct
    15421 ctatgacctt accaccttgc agcgggaggc taaccggctt ttcggctata ccgccaagca
    15481 gacccttgac tatgcccagg cactgtatct aaagaagctg ctgacctatc cgagaacgga
    15541 tagtcaatat cttaccgacg atatgctgcc cgccgtggaa agccttgtgt ccggcctgtg
    15601 ggagctggtg ccgtttgcca agggcctgaa cctttccccg cagtttgacc gcatcctgaa
    15661 cagcaaaaag gtgtccgacc accacgccat tatccccacc gctgaatttg tgaagcaggg
    15721 ctttggcact ctggccgaga gtgaaaaaaa gctgctgtcc ctgatctgct gcaagctctt
    15781 atgtgccgtg gccgggccgc atatctatga ggccgtcacc gccacattta cctgtgccgg
    15841 gcaggagttt accgccaagg gcaagaccgt cctttccccc ggctggaaag agattgaacg
    15901 ccggttccgt tcttccttaa agaccgacgc cgacgaggac gccgaggcgg tgcgggagct
    15961 gccggagctt tgcgagggcc agacctttgc agacgtggcc gcctctgtca ccgagcattt
    16021 caccacgccg cccaagccct acaccgaaga tacgcttttg tccgctatgg aacgggccgg
    16081 ggccgaggat atgccggagg atgccgagcg caagggatta ggcacaccgg ccacccgcgc
    16141 cgccattctg gaaaagctgg tgcagatggg ctttgtccag agaaaaggca agcagctcat
    16201 tcccaccaag gacggcatca atctggctgt ggtgctgccg gaggcgctta cttctcccca
    16261 gcttactgcc gaatgggaaa accggctgac cgagatcgcc aaggggcagg ccgatcctga
    16321 cgaatttatg gacggcatcg agacgcaggc gcgggagctg gtgcagacct attcctgtat
    16381 cagtgaggaa aagcagaaat tgtttcaggc cgagcgtgtt cctatcggga cgtgtccccg
    16441 ctgtggtgag gctgtctatg agggcaagaa aaactactac tgcggaaacc gggcctgcca
    16501 gttcgtcatg tggaagaatg accgattttt tgaggaacgc aagaaagcgt tcaccccgaa
    16561 gatcgccgct gcgctgctca aaaccggcaa agtcaaggta aagggcctct attccgtaaa
    16621 gaccggcaaa acctacgacg ggacggtgct tttggctgat accgggggca agtacgtcaa
    16681 ctaccgcatt gaacacagga gctaaaggac agtaacacag caagcatagg gagtgtggct
    16741 acactcccgg taaaatcccc cggccgcgtc cctgccgggc cggggatttt tgcttgttgg
    16801 ggaagtcccc aaccccctat tttttgaaac agaacagaga aaggagtgac cgcgtgaacg
    16861 aagtattttc tatccaagtc cataaccggc agtttttgga acagggcaaa caaggcgtct
    16921 ggctggattt gcccaccaca accgaaacgc tgcaagccgc cctgcgggat gttggcatta
    16981 ctgccgacaa tccgcaggat ttttttatca acgggtattc ctgcccggag gacagacacc
    17041 ttgccattcc ctatgacatg gtgctggccg ccgacgtgga cgagctgaat ttccttgccg
    17101 cccggctggg ccagcttgac gccgccgaga tcgcagagct gaacgccgcc ctgcaaaatc
    17161 cccgtggcgg ctttgagaat atcggccaga tcatcgacta caccgaaaat gtggattact
    17221 atgtgcatct tcccgacgtt aggggggatg gacagttggg cgactactac ctgaaccgtt
    17281 ccggcatggt ggatatgccg gaggaatgga aagccgggat tgatacggcg cagtttggac
    17341 gccacattgc ccagcaggaa caaggcgttt ttacccagta cggctatctg gtgagaagcg
    17401 gcgacgaatg gcagcgcgtc catgagggcc agccggtgcc ggaggaatac cgggtgatgc
    17461 actaccccca gccggaagct gaccgggagg aaccgcaggc ccagcagccg gaggcatccg
    17521 aaagccccga caaagcgccg cccccggtta tcccgatcat gctggacggc atgaacagca
    17581 aagaacgcat gaaagtgatt actgaccgtc tggaaaccgg cgtacaggag ctttttgaaa
    17641 gtagccgcta tatggcttac ttatccgcta tgtccaagat gcacgattac agtctgaaca
    17701 atacgctgct gatcgccatg cagggcggtt cgattgtggc gggctataac aggtggcagg
    17761 atgaatttga ccgccatgtg aagcggggcg agaaaggcat taagatactg gccccggccc
    17821 cgttcaaggt taagcagcag atggagaaaa ccgacccggc cacccagcag cccgtgatcg
    17881 gcgcggacgg caagcccgtg accgaagaac aggaagtgac ggttccggcc tttaaggtgg
    17941 tgacagtctt tgacatcagc cagaccgagg gcaaggattt tcccatgccc tatatcagtg
    18001 aacttaccgg cgacgtgcag cagtatcagg atttctttgc cgcgctggaa cggacatcac
    18061 cctatcccat aagcattgag ccgatttcag acggggccaa gggccgctgc ttctacgcaa
    18121 aacagcgcat tgccatcaac gagggcatga gcgaattgca gaccctaaag accgccatcc
    18181 atgagattgc ccatgccaag ctccacgcca ttgaccggga ggcccccgcc gaggaacagg
    18241 cggcccggcc agaccgcagc acccgcgagg tacaggccga aagcgtggcc tataccgtct
    18301 gccagtatta cgggctggac acgtcggact attcttttgg ctatgtggcc gattggagca
    18361 gcggcaggga gttatccgag ctgaaagcct cccttgaaac catccgggcc acggccagcg
    18421 aattgataac cgagatcgac ggccattttg cccagcttca gcaggagcgc gaggcccggc
    18481 aggaacagga ggccgtcacg gttgacgtta ccccggaggc agcggccccg gcgcaggccg
    18541 aggaagaaca ggccccggcc cttgatccgg cagccgagcc gcttgtgact gtgctatgga
    18601 gcgaaagccc ccagctaaag gacggccagc aaatgccgtt gcatgaggcc gacgcgctgt
    18661 ttgcccgtct ggatgcagca tatccggcag aggcaggcta tgacaaaacc gcgttccgca
    18721 ttgactgtat ctttcagggc gagccggaca gctacgaggg gcggcaggat tttggagata
    18781 gggacggttc cctgatcgaa catatccaga gctaccacca attttacgcg caggacgaaa
    18841 actggaaaaa gcatgtaatc gctacaaccg gcatagaggg ctgggagcag gacaaggccc
    18901 atcgggatat gctgttaggc gagtttgtcc cctatatgaa gctgcattgc agccttgccc
    18961 aaatggaaca gacggcgcag ggccgcttac agtccgggga aaccctgacg ccggaggaaa
    19021 cggcctattt gggggcgctt ctctcttatg tgcaggagtg ccgccccatg ctcaatcagg
    19081 gccagtatca gttgccggag ccgccgaaac tggctgactt cgaccagagc ttgcaggact
    19141 acaaagcaca ggtacaggcc gagatcgcgc aggaggccgc cgcagccggt atgaccgtgg
    19201 aggaatacgc ggcggctggc tatgaagcac cccaacagga caccttttcc atctaccagc
    19261 ttcgaggcgg ggaggaaacc cgcgactatc ggtttgagcc atacgagcgt ttacaggccg
    19321 cagggctggc cgtggacagt gccaactatg accttgttta tacggcaccg ctggataaaa
    19381 gcacgtcttt ggaggatatt taccgcacat tcaacatcga ccacccggca gattttaggg
    19441 gacacagcct ttccgtttcc gacgtggtgg tgctgcacca gaatggacag gacaccgccc
    19501 actatgtaga cagcttcggc tatatggaag tgccggagtt tttgcgggaa aatcccctgc
    19561 gtaccgccga actgtctacg gagcagaacg aaaacatgat tgacggcatt atcaacaata
    19621 cgccgcccga accgcagccg gaggaacccg aacagctatc ttttgaggat gtggcagttg
    19681 cttccggcca gacacaggag gaacccccgg aggctgcgcc cccgcaaacg gctgtccgct
    19741 attatcccat caatgaggga gccgcccgcc gcgccaagga agccatgagc ttttctgact
    19801 accggcccgg cagcgccacg gcggaatacc ggcactatgt cgatcaggcc gtggaaattg
    19861 cggagcgcca gaaaaagcgt gtggagccag agtatcacga aaagatagac agcctccttg
    19921 acacctacgc ccgcaagctg gccgagaaca tgaataaggg ctatgagatt accgcccgcg
    19981 tcccctctgt cctgattgcc gggccgtcca atttcccggt acgggcgaaa gaaaagcaga
    20041 acgccgccag tgaccgcaac atggaggaat ttcagtacat tcagggcttg cttgacaaaa
    20101 tccgcagcac cggcatgggt ggtatcagcg ccgacgatcc gcaggccgtt tccaagctgg
    20161 aaaagaaact ggaaaagctg gaagcgtcgc aggagttgat gaaggccgtc aatgcctact
    20221 accgcaagca tgggacgctg gacggatgcc cccatctgat cgaaagaggc attgaaaacc
    20281 tgaaagcgga tatggcgtcg ggctggcact atgagaaaaa accgttccag tcctggcagc
    20341 tctccaacaa taacgccgag atacgccggt taaagggccg cattgaggaa ttgacccgcc
    20401 aaaaggaggc ggcctatgtg ggatgggagt ttgacggcgg cactgtggag atcaaccggg
    20461 tggccaaccg cctgcaaatc ttctttgagg ggaagccgga tgctgctgta cgcgacgagc
    20521 tgaaaagcaa cggtttccgc tggtcgccca aggccggggc atggcagcgg cagttaaacg
    20581 acaccacaat ccgcgtcgct gaccgtatca agtgcatcca gcccctttcc ggcgaaaagc
    20641 ccagcgcctt acagcttgcg gcccgcaggg agaaagaaaa gccctctatc cgggcgcagc
    20701 tcaacgcggc caagaccgaa caggccaagc agccaccggc gcgggaaaaa tcaaagggat
    20761 tggaggtaga gtaaatgcag aagtttgaaa atgtggacgt tctggccgcg ctggaacaga
    20821 tcatgcggca gaacaccgcg ttttatcaaa gtgactttgg cattgacaaa gacattatca
    20881 ggcgggatgc cgccagcgat caggccgcag acaagaccct gctctggatg tcccggccct
    20941 ccgggacgta ctgtttccgg gaacgtgatg ttttcctgaa agacacccga cagtacaaca
    21001 catggaaatt ttacggggag cagacccgtg acaagatact ggcctacgcg gtggagctga
    21061 ccggcacaca gggcggcact atccggggca atctctatga gctggactat ccgcagcatt
    21121 tccggcacgt cattgaaacc gcccagccgg tgagtgtgaa ccggctcttt tatgagcatg
    21181 gcacccgtga catcccggag agccagcgtt ttgacggaag ccctgaccgg gtattgggaa
    21241 actttttgta ctatgaggcc cagccccatg acccggctgt gctgcaggag gcgctacgga
    21301 cggagcagca cagccggggg cgggccgtcc ccggcgattt caaagtccac gtcaccgctt
    21361 tgcatgacag ccggattgaa accgaggccc ggcgtattgt ggacagcctg aaagatctgt
    21421 ccgcgcctaa cagccccaat aaaacgcatt tcatggtgga gatctccccg cactttgcgg
    21481 cgattgcttc caccaaggat aatgaccggc tctttgccat gctgccctat aaatccctgt
    21541 gttttaccgg gatgaaaggc aggcatggcg tgtatgccgt gattaaccgg gacgagcgcc
    21601 gggatgtgag tattcgcagg ccccggccct ctatccgcaa gcagctatcc gacagcaaac
    21661 aggccgccag cccaaaaaag gcggcggcca gaaccaaaaa gaatgaattg gaggtataag
    21721 gaatgatgca ctttaccgtg gaggaagaaa acctgatctg tatgtaccac aatgcagacc
    21781 ggcgcagaac gataaacagg ctcaccgccg tcatgccggt tatggatggg gatatgcggg
    21841 cgcaggccca gcagaccctt tccaagctgg aacgcatgac ggatgccgac tatgacggcc
    21901 agaagttcca cttcacagac gaataacgaa cagcagacgc cgggcgcggc ggccatgtgg
    21961 tcgcttgcgt ccggcgtctt ttctttttgc ctattcctac gcatttagaa cccggtattg
    22021 tcggggatag gatgaagtat tcgcttgccc ctgcaaacat gcgggagaag ccttgcagcg
    22081 ggcggttttc aatcccttaa atgcgtaggt tgcagctata attagacccc tgaaacagat
    22141 atagccgcgc agcgggtgta tctgtttcag gggtgtgcag gtgatagccg caaagcggcg
    22201 taagagggtg cagccctctt gccgtctatc tctgttccag cgggaagctc ggcaatgctt
    22261 ccagcagttt cagggaaatg cgctgccgta tatcttcgtc aatgactttc ttctttttgc
    22321 cgtttgcctg tctgatctcc accgtggaaa gctcgttgat gtagtcagca taatgggcca
    22381 acactttttc cgtggcccac ctctcaccgg caacggcggc tttgatcgtt tcatagtcca
    22441 gcagcttttc ttgtccgtcc atcctgatac ccccgtcaga ctgatttttt ctatgatacc
    22501 atattcggaa gcatggaacc agagaaaacg gcgcttttct gctggtaaat tctacgcatt
    22561 tagaacagca cttcggcggg gataggataa aacacccaca taccccgctg accatgccgg
    22621 aaaagccttg aaatataagg gcttttacag ctctaagtgc gtaggtttcc agtatctttt
    22681 ccgctggcgc tcggcctctt tgcggcggcg catccgtttg gagcaggccg cgcagtattt
    22741 ggcccggtta gacttcggcg tgaacgtggc cccgcactca cagcagcgtt tcacttcgtc
    22801 ccggtctttg gtgatctcgg catacagggc cgcatccagc gggaggacag cggccttaaa
    22861 ccagcggcac agaagcgaat aggaaatgct ctgtacgcaa atacattctt cgccgtcgtc
    22921 cagcaacagg cagttgccgt cacaatagtt gcagcactca tgcgtcagct tccgggcctt
    22981 gcgatattga gggtaattca ttcgtggaat actcatagct cttgcgtcca ttcctttccc
    23041 ggcgtcatac gcaaaatgcc gtccacattc tgcttgatga tgccgtattc ctgcatctgc
    23101 tttttcgctt cgccgtactt ctcatacagc cgttcctttt cctcggccaa tcgcttgtac
    23161 tcggctttca gggcgtacag atcggggagc tttttcacac cctgtccctt tagggccttt
    23221 gccgcagctt catacaaaat caacgtgctt tcatgctcac gccggaattt tgccttatcc
    23281 gctgcattgc ggtattccat agccacgggc cagagctgct tgtaggtaga aatattcttt
    23341 atcagcaccg ccatatccgc aagccggtgt tccatagctt tgagggtagc ggcggcctcg
    23401 tcgctggcgg cggtgatctc ggccactttg ctttccaaat ccgggtaggt gtctatccca
    23461 tgttcagtca ggaaattcaa agtctttgcg gcctgcttca aattgtggag cttcgcccac
    23521 ctctcatagc ctgccgactg ctgggcctta atgttgtttt ccagatcaat ccgcaaagaa
    23581 atccccttgc gctctttggg cgctctggtg ataacgcggc ctttgatacg ctctttgatg
    23641 gcttcctcgg tgtaggcttc ccccaatgtc ttgcagcggg taaagcgttc ctgtccggga
    23701 gcgcggaaag aaataaactt tcccggcttg atctcatagc cctgcgcctg catgagccgc
    23761 aggaaatcat caaaatcttt tgcctgcggg atagcggcgt caatggctgc tttgagcttc
    23821 gctttccagc tcgtcccttt ccgctgggcg tcccactcgg catagctctt gcccttactc
    23881 tggccgggct tcaccacgga caatccgttt tccttgcaca gcctgtcgct ggtgcgccgg
    23941 atataggcat agctctgttt gttggaaatg tacttgcgct gatttaccat atccacggca
    24001 cagaaaataa tgtgattgtg gacgtggccc ttatcaatat gggtagtcag cacataggga
    24061 tatttccctt gcagcacttc ctcggcaagc tgcttcccga tctcatgggc ctgttccggc
    24121 gtggcttcgc cgggggcaaa ggattgtatc aggtggtggc ccagattatt gcccttttgg
    24181 tatgcctgcg ccagcagcat ttcaaattca atgtccgctg tttcataaga gcaggcaaag
    24241 gaggccacca gcagcttgcc gtcagttttg tccgggttct cgatgtagtc aagggctttt
    24301 ttcagcgttg acttgatagg atgtatcttt gtaactgcca tatctgcgcc agcgccccct
    24361 ttatatcctc gatgtcctgt gcgtacaccg gccccatacc gttcagcctc tttgcaatct
    24421 gattgacgtt gacgccgatc ttctgtatct cggcggtctg cgcccggatg tcgctggtgt
    24481 ccatgttgac gatatagccg tcaatgagca tcttccgggc gtaggctgaa aagttcttcg
    24541 tatgcagcag cgccattttc tgttcaatca tagcccgttc ctccggcgtc acagggacgc
    24601 gcagcacgat ttttcgcttt ctgtttgcca tgcttcaccg tcctttccat tcaggggttt
    24661 ggggatttcc ccaacaagca aaacggacgc ggcccggcag ggacggggca ggccgttttt
    24721 ccgggagtgg ctacactccc tatgcttgct acgttactgt ttctccacta acaagacgtt
    24781 tccaaagccc caaactaccc gcaaaatagc cctctggaaa gaaaaaagtg caaaaaaata
    24841 gaagctacgc tgtgcagctc ccgctaaaag taaaacagag gatgccagtt acacatcctc
    24901 cgtttcattc ttcttcggct tttcaattag tatggcgctg tcaatcgcgc cctcgatgat
    24961 cggcaggtat tcttcggggc agagtttcag cttgtggctg accctttgcc gcagttcgct
    25021 ttcctcccgc atgatctccg ggttaaagta gcgttccaca ggaagcccgc aggctttaat
    25081 aagctgtatg acaaccggca gactgggaat ggcccgtcgt tttcgatgtt ggcaagatag
    25141 cgccagtcaa tatttatttt ctctgccatt gctttgcgcg aaacgcgctt tgcttgccgg
    25201 gccgctttca catccgcgcc gaaagtttca aagccgggac aatcttcaat attcgccata
    25261 tcgcacctcc cacttacatt gtatatttca tactctgccc gtggaatgtt ggtatatgca
    25321 cctttcttaa agtttatatt tcacattttg tttcttttat tcttcgagca aaagaattat
    25381 aatgtaccct gtggaggtgt actatggact acatgacgtt gaaagaggca ggcgagaaat
    25441 ggggtgtgcc cccacgatgg ataaactact attgtgctgc gggacgcatc cccggcgctg
    25501 taaagatggc gacgatctgg ctcattccca aaactgcgga aaagccgatt gacaggcgta
    25561 caaagaaagg aaaggcggtt actgaatagt ataatgaaac cggcgcattt tggatatggt
    25621 tttgaagaga gagaaagcat ggtattttgt cacggaaaaa ctataagatg atagatggca
    25681 ggctgctcca gaccgataaa aagtattctc atctgaaaca gaaagaaaag atttacacat
    25741 ggatgtatga agaagcgaaa ctttatcatg acagaaatgg aaaatgcccg aaacaaagac
    25801 gaggaagctg ctgctgtatc agccgtatat ggtagaattg aaaaggccgg catctggatt
    25861 ctttatggtg aagtctccag acattggata actgctggtc taatgcgcct ttgagtatgg
    25921 ggtgattgat tttaataccg gggaggtacg gctttttgag gaaaatattc tgggatttac
    25981 atttggcgat tattacattt cctgtaactg caaggacacg gatgatgaag atatgaggaa
    26041 tatagacttg ctgattttct actgtcttga acggtattag gactgaatct gctgcgcgga
    26101 gtgcggcaag agcgaccgga gggagtacac acaggccctg cctgtgtgaa aagccatacc
    26161 gcaaggtgca ttcgcaaaaa agaggccgcg cattttgctg aggcttgggg tgtccccaac
    26221 aagcaaaacg agaacgccgc aggcgggcaa gtggtggatc agaatatccg taaaggatat
    26281 tctgatccat tgcttgccag tattatcggg atgttttgac aaccgctgta atcgaaacat
    26341 cccaaacatt aagaaggtgt taattattat tatcttgatt taattcgttt aaaccaataa
    26401 tatagataca tacaccatga aaagaagcga gtatcccaat gacggatgat taaaatccga
    26461 aaagaaatcg ctttgaaact acagggaaac tacagactgt tatgttatct tcttaaaatg
    26521 gagggatttt tatgtcgata cgaattctac ttgtcgagga tgatgatcat atctgtaata
    26581 cagtaagggc gtttctggct gaggcaggat atcaggtgga tgcctgcaca gatggaaatg
    26641 aggcatacac caagttttac gaaaacactt atcaactggt tattcttgat attatgctgc
    26701 ccggtatgaa cgggcatgaa cttttgcgtg aatttcgtgc gaaaaatgat actcccattc
    26761 tgatgatgac agccctgtcg gatgacgaaa accaaatccg ggcgtttgat gcagaggcag
    26821 acgactatgt aacaaagcca ttcaagatgc agattttact aaagcgggtg gaagccctgc
    26881 tgcggcgcag cggtgcgctg gcaaaggaaa tccgtgtcgg caggctgaca cttctgccgg
    26941 aggatttcac ggtactttgt gacggtacag agctgcccct gacacgaaaa gaatttgaaa
    27001 tccttttgct gctggtgcag aacaaaggca gaaccttaac gcatgaaatc attttgtcac
    27061 gtatatgggg atatgacttt gagggtgatg gcagcacagt ccacactcat atcaaaaatt
    27121 tgcgggccaa gctgccggaa aatatcatca aaaccattcg cggtgtagga taccgattgg
    27181 aggaatcata ataatggaaa gaaaagggat tttcattaag gttttttcct atacgatcat
    27241 tgtcctgcta ctgcttgtcg gtgtaacagc aacactgttt gcacagcaat ttgtgtctta
    27301 tttcagagtg atggaattac agcaaacagt aaaatcctat cagccattgg tggaactgat
    27361 tcagaatagc gataggcttg atattcaaga ggtggcaggg ctgtttcact acaataacca
    27421 atcctttgag ttttatattg aagataaaga gggaagcgta ctctatgcca caccaaatgc
    27481 caatacatca aatagtttta gacccaactt tctttatgtg gtacatagag atgataatat
    27541 ttcgattgtt gctcaaagca aggcaggtgt gggattgctt tatcaagggc tgacaattcg
    27601 gggaattgtt atgattgcga taatggttgt attcagcctt ttatgcgcgt atatctttgc
    27661 gcggcaaatg acaacgccga tcaaagcctt agcggacagt gcgaataaaa tggcaaacct
    27721 gaaagatgta ccgccgccgc tggagcgaaa ggatgagctt ggcgcactgg ctcatgatat
    27781 gcattccatg tatgtcaggc tgaaagaaac catcgcaagg ctggaggatg aaatcgcaag
    27841 ggaacatgag ttggaggaaa cacagcgata tttctttgcg gcagcttctc atgagctaaa
    27901 aacgcccatc gcggctacaa gcgttctgtt ggagggaatg cttgaaaata tcggtgacta
    27961 caaagatcat tctaagtatc tgcgcgaatg catcaaaatg atggataggc agggcaaaat
    28021 catttccgaa atactggagc ttgtcagcct gaatgatggg agaatcgtac ccatagctga
    28081 accgttggac atagggcgca cggttgccga gttgctgccc gattttcaaa ccttggcaga
    28141 ggcaaacaac cagcggttcg tcacagatat tccagccggg caaattgtcc tgtccgatcc
    28201 gaggctgctc caaaaggcac tatccaatgt catattgaat gcagttcaga acacgccgca
    28261 gggaggcgag gtacggatat ggagtgagcc tggtgctgaa aaatgccgcc tttttgtttt
    28321 gaacatgggc gttcacattg atgatactgc gcttccaagg ctgttcaccc cattctatcg
    28381 cattgatcag gcgcgaagca gaaaaagtgg gcgaagcaga aaaagtgggc gaagcggttt
    28441 aggacttgcc atcgtacaaa aaacgctgga tgccatgagc ctccagtatg cgctggaaaa
    28501 cacctcggat ggcgttttgt tctggctgga tttaccgctc acatcaacat tgtaaatatt
    28561 taaaacttaa atgattttgg gctctttgtc aaataggact gatagagtga gataagaac
//
LOCUS       DAFLWC010000270        13213 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.guided.081, whole genome shotgun sequence.
ACCESSION   DAFLWC010000270 DAFLWC010000000
VERSION     DAFLWC010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13213
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.guided.081"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            complement(204..2162)
                     /locus_tag="L1V17_003089"
     CDS             complement(204..2162)
                     /locus_tag="L1V17_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBN1237754.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(2159..3031)
                     /locus_tag="L1V17_003090"
     CDS             complement(2159..3031)
                     /locus_tag="L1V17_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBN1237755.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(3373..4245)
                     /locus_tag="L1V17_003091"
     CDS             complement(3373..4245)
                     /locus_tag="L1V17_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBN1237756.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            4373..4942
                     /locus_tag="L1V17_003092"
     CDS             4373..4942
                     /locus_tag="L1V17_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBN1237757.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            5009..5746
                     /locus_tag="L1V17_003093"
     CDS             5009..5746
                     /locus_tag="L1V17_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBN1237758.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            5977..7245
                     /locus_tag="L1V17_003094"
     CDS             5977..7245
                     /locus_tag="L1V17_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBN1237759.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            7732..8196
                     /locus_tag="L1V17_003095"
     CDS             7732..8196
                     /locus_tag="L1V17_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBN1237760.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            8180..8809
                     /locus_tag="L1V17_003096"
     CDS             8180..8809
                     /locus_tag="L1V17_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBN1237761.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            9163..10641
                     /gene="msr(C)"
                     /locus_tag="L1V17_003097"
     CDS             9163..10641
                     /gene="msr(C)"
                     /locus_tag="L1V17_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBN1237762.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            10688..11134
                     /locus_tag="L1V17_003098"
     CDS             10688..11134
                     /locus_tag="L1V17_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBN1237763.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(11333..11848)
                     /locus_tag="L1V17_003099"
     CDS             complement(11333..11848)
                     /locus_tag="L1V17_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBN1237764.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            11965..13167
                     /locus_tag="L1V17_003100"
     CDS             11965..13167
                     /locus_tag="L1V17_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBN1237765.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         4116 a         2424 c         2708 g         3965 t
ORIGIN      
        1 agaggttgta aaaaagctgt tctgcatcaa gtaataagaa gagtcaaata aaaaatagct
       61 cttcatatgt tacgtttggc tggacttatt accgcggagt tggcaggaga acgccgtttt
      121 tattcggaaa aaggagctga gacaagattt ttgtctcagc tcctgtttgt ttatcgataa
      181 aaaagtctgg ggaagacgat ggctcaggct ttgttggaaa cagagccgat tttatcattt
      241 gcttttacat cacgtgcggg ttcgatttct aagctttgga ctttgtcgcc atttgtgaat
      301 acaacgacca tatccgtgtt tttgcctgca gattgaatag cggcaagatc aactaaagca
      361 atcaattgac ctcttgcgac tttttgacct tcttttacat ataaagtgaa tggttcgcct
      421 tttaagtcaa cagtgttgat gcccatatga agcaagactt cgataccagc atctgtttgg
      481 attccgacag catgtttcgt tgggaaaatg tttgtgatcg taccagcgat tggagagaag
      541 atttctccat tttctggtaa tacagcatag ccgtcaccca tcattttttc cgcgaataca
      601 tcatctgaaa cttcagtgat tggaatcagt ttcccatttg cgatagcgta aatatcttgt
      661 tcgatcgttc caccggcaaa tgtttctgtt ttaaccacgg tgtttgtttg tgcaggtcgt
      721 gttgcagcac caccatgtag ttttgccatc tcatctgcaa cgaattgtac ttctgtacct
      781 acgatgactt gcgcattttt tccgtcgatg atcttcatac caggtacgcc agtggctttg
      841 attttatttt gatcgatcag gcctgtatct ttgacttgca aacgaaggcg tgtagtacag
      901 ttatcgatcg aagttacatt gtcggctccg cctaatgcag cgtagatttt gcttgcttgt
      961 gccgcatatt tattgtctga attagtcgtt gcagtatcgt catctgaaag atctgcttcc
     1021 tcgcggccag gagtcatcag atggaatttt ttgatagcaa agttaaagcc aaagtagtaa
     1081 atcactgctg ttactaatcc ttggacgatc aacatcaatg gctgattcgc aatcggattt
     1141 ttcaaagata ggaagtaatc gacaaatccg gcactaaagg caaatcctgc tgtccaatgg
     1201 aagaatgcac tcactgctaa agaaatccca gtgaaaattg catgcaagac atataatggc
     1261 caagcaacga acataaatga gaattcaagt ggttctgtta caccagtaaa gaatgaagca
     1321 aaagctgctg ctaacatcaa ggaagctgtt tttgctttgt tttctggacg tgcatttctg
     1381 taaatagcat atgctcctgc tggaagcccg aacatcatga ttgggaaaaa tccagcttga
     1441 tacattcctg ttacgccttt tgttccttca gaagccaaaa atttaccaat atcattgatt
     1501 cctgctacgt caaaccagaa cacggagttc attgcttgat gcaatcctgt agggatcagt
     1561 aaacggttga agaagccata aagacctgca ccaccccagc ctaaactcaa aatgaattta
     1621 gcaaaagaaa ctaaagcaga gtaaaccgga ggccatacga gcagtagcac tgcactgatc
     1681 agcaacatga caaaggcagc caagattggc actagacgct tgccgctaaa gaaagataaa
     1741 gccatcggta attttgcttc gtggaaacga ttataaagag ctgccgcaat caatccggca
     1801 ataataccaa taaatacgtt actgatctga gcaaaagatg gatcaactga ttctggtttg
     1861 atattcaata aagtagctac tgaatcagtt tttaaaacat ttactggaac ttcaaatgcg
     1921 accaaacctg ccaaggcagc agcacctgat ttgtccactg acatccctag tgctaaccca
     1981 acggcaaaca gcaaaggtaa ttgacctaaa actgcgttac cgccagcttg taaaaaatga
     2041 gcgacaatgt cgttactata agatgcccac cagtttccga tccctactag taaagcagca
     2101 gcaggtaaga ccgcaactgg aagttgaagg gaacgtccca ttcgttgtag atatgctttc
     2161 aatttttttc ctcctcatga ttgttaacat ttgtttgtac gattgcgctt cttaaacgct
     2221 cgatatggat ggccaagtaa cccagttctt ctttcgtgat cgcgagctgg tattctttgg
     2281 tcagcaacac acggattttt ttagaaatct tatagctttc tgggtatttt cgtttgacca
     2341 tttctacgat ttccgtgtct aaaacagcat attgttgcgc atgggttcgt tgtagaagca
     2401 gtcgtaaatg attcaccagt cttgaataat tcagtgaaaa tggttctgaa tggatatctg
     2461 tttccaattc tgattccact aaatggatga tgtcagatac aatcgtcact tcacggatac
     2521 tgcgatggtt attgttccga ccgcttcgtc cgctgtgaat atggattgcg atatatcctg
     2581 cttcgtcata agtatatgga atcccaagct cttttgtcag atactctact gcccattgag
     2641 caatactgaa ttcatcactg taaagcactt cgatttctct taaaagtttg ttgcggatga
     2701 cgataccgtt attaatgttc tccgcagaaa aagcaatgtg gtcggtcaaa gcgatcaata
     2761 catgttcatt caacttttcc atcaaaacag tttccgcatg atcaatgatc gtttctgctg
     2821 caaataaaaa gcgttcatca atctgattaa gtaaattttg caacttgatt tgaccttctg
     2881 gttccatgac aaatatccgt tcgacatcac gatcaaaaat caaatcattt ctttttctgt
     2941 caaatccaat cccttttcca atagctactt tttcctgtcc accgtcatct accaatactg
     3001 cattttgatt aaagatcttt ttgattttca tgcgcgcacc ctttttgaag atttggtttt
     3061 cacgtttgct agaccagttg attgcggcca aacaaaaata gacacgaaaa acctcctagg
     3121 gaaaccatgt tcctcagaga tttttcatgc ctagtatgat ctagtcacat gaaacgaatt
     3181 attgttaacg taatcaattt tatatagaca gttatgtttt gtcaattctt tttttataat
     3241 tatagtaatt tactggaatt atcagaaata aaaggaagga acaaattaag aaacttatgt
     3301 tatttaatca ttggatcttt tgcttaactt attcgttgtt aaaaagctga aagcgaagga
     3361 aaaaaactct acttaactgt atttctccgt taggacatct aaaaatttac gagcagcagg
     3421 agaaagaggc tggtcttttt tccaaatgag attcagtgaa gcttgtaatg gcggatcgag
     3481 tgggatgaat actttttccg tcccataagt attgatgatc ccatctagag ctaatgcacc
     3541 aaaagtcccg ttatcgacca tcaaagaagc attgtacaat aagttatatg ttccgacgat
     3601 cgataactga tctatgctga aacctagcca ttcagctagt tgactgtcca ctgacgtttg
     3661 ccgggaaatg atcaaaggaa cagttttcag ttcctgcgga tggatgactg tttgctttgc
     3721 taaaggatga ttccgatgta tcaaaagtcc ccaacgatct tgggctggca gtcgaaatga
     3781 ctggtatttt tgtttgtttg tcggttcgat tacgagtcca aaatcaagta atccgctatc
     3841 cagtttgtct atgatatcat ctgcattccc gctatataaa tgaaactgga tatcaggatg
     3901 cgccttgatc aacgaatgaa ggctatcaga aatgaaagag attgctttag tttcgcctcc
     3961 gccaatgtag atttctccag agatgattgc gtcatttgtt aaattgttcg ccgttttttc
     4021 taccaacgac aagatttctt ttccttttga ataaagatat cgaccagaat ccgtcaactg
     4081 tatctctcgg gagcctcgag tgaaaagtgt cacaccaagt tcttcttcta aatctttcag
     4141 ttgttttgag agagtaggtt gcgtgatatg cagagatttt gctgctcggc tgatattttt
     4201 ttctctagct actgctaaaa aatacgtcag tatacgaata tccatttttt ccctcctgtt
     4261 tttaaaaaag cataccacta agtatagtta aaaggaatag ttaagtatgt tttataagta
     4321 ttagacatca taagccgtcc gttataaagt aaggataaaa ggagggagca aaatgacaag
     4381 cctcatcgaa aaacaaatcg tcaataaaga gattcgagta acggatccgc tctttgaagt
     4441 gatccatcag atccaagcgg aaaacgaaga gcctttagca gcgctgaata ctgggtacca
     4501 tgaaccagca gatatccgca aacggctaga aaatatcatt agtgacaaag tagatgatac
     4561 ggtgactgtt ctgctgcctt tttatacaga tttcggcaaa catattagta tagggaaaaa
     4621 tgtctttatc aatcgtcaag tgatgttcgt tgacttaggt ggcatctgtt tagaagattc
     4681 agtattgatt ggtcctcgtg tcaacctcat cacggtgaac catctaaccg atccaaaaga
     4741 acgaagaggc ttgtcagtaa agccaatcca catcaagaaa aatgcttgga tcggagcagg
     4801 agcaactatt ctgccaggcg taacgattgg cgagaatgcc attgttgcag cgaatgcaac
     4861 tgttacgaaa gatgtcccag acaataccat cgttgcagga atccctgcca aaatcgtcaa
     4921 acctgtcgaa cggattattt gaacagtaag atgaaataag agatagtgag tataagcaag
     4981 agatttttca aaacaggagg agaatagaat gaatgattta tcagaaaaag tgattgtcat
     5041 catgggcgct tcaagcggaa tcggtgaagc aacaacgaag ctattagcag aaaaaggggc
     5101 taaactagtt atagctgcac gccgagaaga tcgcctaaaa gcaataaaag aatctttacc
     5161 agaagctgag ctatatattc aaacagcaga tgtaagagat tttgcacaag tccaagcagt
     5221 tatcgattta gcgatggaaa agttcggtcg aatcgatgta ttgtacaata atgcaggaat
     5281 catgccaacc gctccattag ttgaaggtca ccgtgatgaa tggcaaaata tgcttgatat
     5341 caacatcatg ggtgtgttaa atggaatttc cgccgtactt ccaatcatgg aaaaacaaaa
     5401 atctgggcat atcatttcaa ctgattctgt ggcgggacat gttgtttatc ctgattccgc
     5461 cgtttattgc ggaacaaaat ttgctgtccg tgcaatcatg gaaggattac gtcaagagca
     5521 acggcaaaat aacatcaaat ctacgatcat ctctccagga gctgttcaaa ctgaattata
     5581 tcaaaccatc agcgacaaaa aggctgctct tgaacttcat gaagcgcaaa aagaatgggg
     5641 attaacatct gaagatatag cttctgctgt agcatttgcg atagaaacgc cagaccggat
     5701 gtctgtcagc aacatgatta tccgtccgac gacacaggaa gtataatcca taacggataa
     5761 tatccagaga gaattacttg ttaaatagtt attcaaacga ccatcaattt aaggcgtgaa
     5821 tggagaagaa tattcttcat ttacgtcttt ttatgcagaa aaagcaaatt tattaaaaag
     5881 aaacaaatgt tatttaaata tggacattga cttgctttta cttttttagt tacactgtta
     5941 tttaggaaaa gtttcataat tcaaaggaga aaaaagatga aagcaaagaa tttattattt
     6001 agcgttattc ttttaggaaa tctagcagtt gccaacacaa cagtgctagc tgaagaatcg
     6061 acagaaactg tcgcaactca gacatcgagt tcttcagaaa caggaattga aaacgataca
     6121 gaaagtactt tgcagtcagc tactgtctca gaaaatacaa tttcaaccga agaaccaaca
     6181 actgaaacaa cagaacaaac acaaaccgaa gacagtacat cagcagaagc tcagaacaat
     6241 ccagagaatg cagaagaaat cacgaaccaa ttgacagatg ggcaaacatt gacacatacc
     6301 catcaagcag atttgtctga attcgaaaac tatactggct atgcttttta tgctcgctca
     6361 tctgctaatt ctcaacaagc gttcattgat agtattgcct caactgcaca aagtttggca
     6421 agtgccaatg acttatatgc atcagtcatg attgctcaag ccatcgttga aagtggctgg
     6481 gggaacagta ctttggcttc tgcccctaat tacaatctat ttgggattaa aggaagctat
     6541 aatggccaat ctgttacgat gcctacttcg gaatatgtga atgggcaatg gattacggtg
     6601 aatgccgctt ttagaaaata tccttcgtac aaagaatcat tgcaagataa cgtaacggta
     6661 ttgaagacga cttcttttca gccaggcgtt tactactatt ccggtgcatg gaaaagcaat
     6721 acgaactctt acaaagatgc tacggcttgg ctaacaggtc gttatgccac tgcgcctaat
     6781 tatggttcta cattgaacaa tgtaatcgaa acctataatc tgacacagta tgatacagca
     6841 ccaacttcaa cttctccgat gtatcgtctg tataaccgtc atacaggaga acatttatat
     6901 acattgaatg ccggagaaaa aaattatctg ccaactgtag gctgggaata tgaagggatt
     6961 gcttggcaag caccaaacag cggacaacct gtctaccgtt tatacaatcc ttacagtgga
     7021 gaccatcatt acacaatggc acaatctgag atcaactctt taacaaaaat cggttggcgt
     7081 tatgaaggtc taagttttta ttctggtggt tccaagccaa tttatcgact atttaatcca
     7141 aatgaaaaaa ctggtaccca tcactatacc ttgagtgcta aggaaagaga ttggctaaca
     7201 ccgatgggct ggagatatga aggaatagga ttttatggtt attaaaaaga ggtagtgaaa
     7261 aagctgccct gcatcaagta gtaagaacag ccaaacaaaa acagattttc atgttttttg
     7321 tttggttgaa cttattaccg cagatgcaag tttttgaaca ccgtttactc aaaaaaggtt
     7381 gtgacaacat cttgtcataa cttttttatt actgtttaag catactgatc caatttctaa
     7441 tattcgacgg gattcttgca aaaggcgatt tcggaaattt ttggcggtgt aaaattatct
     7501 actgcagaag agctatcttc tatagtttga taagaatcaa taatcttggt tttagcgttg
     7561 tgctttcttt atcatttttt ccgttcattc tacaaaaaat ttcttttctc tatacttttc
     7621 tattgagagc gtttttttta ttacacagct gattctttga cttttttctt tttttattct
     7681 attattgaca agtcaatcgt tgacgagtca attattagaa aggaggaaat tatgtcttta
     7741 gaagagatta gtcacctttt atatcaaatc aaattagccg atcaaaaaat cgtccagatc
     7801 tttgaagaaa atatcggtat aagtcttact agatacgaga tcatgatgag actgaaagaa
     7861 gaaaatccat tgctacaaag cagtttgcaa gaaaagttgc agattgatca aggagcagtt
     7921 actcgtcatc tgaaggtatt ggaagcaaat ggctatgttt cgcgtcagag aaatcctcag
     7981 aacaaccggg aagtgtatgt agcgctaaca gaaaaagccc agaagaaaat caagcattgt
     8041 gaaatggacc ataaagatac aggttccgtg ctatccccgg ctttcagcga tgtagaaatg
     8101 aaacaatttc taacactttt agataaattg aatacccaac tttgcaatat aacaacagaa
     8161 acgaaagagg ttaataataa tggaacaaaa aaatgatttt tcaacaatta tgactggtag
     8221 aagatccgtt cgcgtatatg atgaaacata caaaatccca cacgaagaaa tgctggaaat
     8281 gatcaaagaa gcgacgactg caccttcttc tgtcaatatg aaaccatggc gctttgtggt
     8341 cgctgaaagc gaggaagcaa aagaaatctt gcgtcctttg atccgtttca atacgagaca
     8401 aaatgatact tcttctgcaa tggtcatgat ttttggcgat atgcaatgtt acgaatatgg
     8461 cgaagaaatc tacaaccaag cttacgaatc agggaagatg ccaaaagaag tcagagatca
     8521 acaattagct gcgatcattc cttattacaa gagtttttca agagaagaaa tgaacgatgt
     8581 agtcaaagtc gattctagct tagcggctat gcaattcatg ttagttgcgc gtgatcatgg
     8641 ctatgaaaca aatccaattg gtggattcga agcagatcag ttggcagagg catttggttt
     8701 ggataaagac cgttatgttc cagttattat tttatcaata ggaaaagcgg tagaagaagg
     8761 ttacgagtct gttcgtttag caccagaaaa gatcactatg ttcgaataaa aggttttcag
     8821 ttactattca gtagctattg ctttttttga atcgtgtgtg gtaacctaat aaaaaaggag
     8881 gtcggaaaaa tgactgcatc gatgaaatta cgtttcgaac ttttgaataa caactaaata
     8941 aattcaaaag acatgtataa acaacaattt catggatgga gtatgtccat tttttcgaac
     9001 gacagtagaa taggtgaaag ctatgacaga tttggtgatt tagtcatagt tatttcgttc
     9061 agagtaggaa aagatgtgat gcagtttttt tgcaaacaga tttttctgct cttttttagt
     9121 atcgataatt gttgttttac atgaaatagg agtgtaaaac atatggaaaa tttagcagta
     9181 aatataacaa atctacaagt cagctttggc aaccagctag aactatctat tgattctctt
     9241 cgtgtctatc agcaagatcg tatagggatc ataggagaaa atggtgtcgg taaatcgact
     9301 ttgctcaaac taatagccgg tgaacttttt cccgatcatg ggaaaatcca aacagagatc
     9361 accttcaact acctgcctca attaacctat ctcgctgaag caaaggacct aaatttggaa
     9421 ttagccagtc atttccagtt aagactggaa gaaacttcag agcggaaatg gagcggaggg
     9481 gaagaacgaa agatcgagtt gatacgtctt ctttcttctt atgaacaagg gatgcttcta
     9541 gacgagccaa caacccatct agatagaaaa agtattgatc gactgattga agagcttcgt
     9601 tattattatg gtacgctggt ttttgttagt catgatcgct attttctaga tgagctagca
     9661 tcgaaaatct gggaagtaaa agacggagaa atccgagagt tttcggggaa ttatagtgcc
     9721 tatctcactc aaaaggaatt ggagaaaaag actcagctac gagaagcaga gtcgatcatg
     9781 aaagagaaaa aacgattgga aaaatcgatc caagaaaaga aaaaacaagc ggaaaagttg
     9841 gaaaaagtgt ccagtaaaaa gaaaaagcaa caaatcagac tggatcggtt gtcttcctct
     9901 aaacaaaaag acagtgtaca aaaagccatc caaaagaatg cgaaaacatt agagagaaga
     9961 ctccaaaaaa taggagaaac aaccaagccg cagcagatga aacaaatccg ttttccagta
    10021 ccaaaatctc ttgaactcca cagccgctat cccatcatgg gacaaaatgt ccaattggaa
    10081 agaagtggga gaacattact ggtaaatggt gattttcagt tttctttagg taaaaaaatc
    10141 gcgattgtcg gtgaaaatgg ttcaggtaag acaaccttat tagaacatat ccgcaaacaa
    10201 ggagaaggaa tccttctctc tccgaaagta agctttcaag tatatcagca aaagggttat
    10261 caaatgacat ctgaagaatc catcattcgt tttgtcatga gacaaacaga gttttcagaa
    10321 tcgcttgtcc gtagtttgct gaatcactta gggtttgctc aggaaacttt gacgaaaccg
    10381 ttatgtacat taagtggggg agaagcgacc cgtctgacga ttgctttgct ttttactaag
    10441 ccaagtaatg tgttgctgtt agatgaaccg actaatttta ttgatatggc aacgatcgaa
    10501 gctttagaga agctaatgca aatatatccg ggaacgattt tgtttacttc tcatgattct
    10561 tactttgtcg agcgtacggc tgatgaagtt tatgaaataa aagggcagaa aataaaaaaa
    10621 gtacttacga gaaattttta aatgtgctac gatgattttc gtgacaaatt taaaggagtg
    10681 gtacagattg cctacaaata aaaaagaagg aataattttt acaacaatga tgtgtttttt
    10741 gatggtcttg gggatgagcg cgtataattt atggctgcat caagatcttc atttatcaag
    10801 tttgttgatt ggtctagtgc ctggattcgt ggtggctttc attttggatg tcttcatcat
    10861 cggtgtgctg gcgaaaaaaa ttgcctttaa actaccagta aatccagaaa gcaaggtcca
    10921 aatgatctta actatttcat gcttgatggt tttaggaatg gtgacatgta tgtctttatt
    10981 cggtgtgatc atggaacaag gaatacctga tcaattattc tctgcttata tgaatgcttg
    11041 gaaaatgaat gtgattgccg ctttaccgtt gcagttgatc atcgttggcc cgctttcaag
    11101 aagtgtgcta aaagcaattc aaagtaatga atgatggaac actgttattt gaaaaaaggc
    11161 cttggcatgc tttttgtcat agtctcttga atgcagttct agaaaaatag tgatccgaac
    11221 gataggtttt ggcctgtcgt tcggatcgct ttttcttttc caactgtatt gctcttttat
    11281 tgaagataat ttgctcttca atagatattt ctagaaaggt tctgtttatc ccttactcaa
    11341 aaaactgctg catttgttct cttacttgct gacaccattg gagttcctgc tgacaaagca
    11401 taattctgcg ctggatcaca acataacgtc caaattcttg tttcttgtct agcgagaggt
    11461 cattcaattt tttttgattt ttttgcatga ttttgttcag ctgttgttct ctagtgaata
    11521 gcagtccagt agctgttgtt ttatcgagcg tcgaaaaagc atagattttt gctagaaatt
    11581 catctttttg cgtaggagcg ggagtttcct ctttgatcca ttcctctaca agagcacgtc
    11641 cttcatcagt caagtggtag atcttttttt gagagtgctc gtctttgtcc aaaacggtca
    11701 cataaccctg ctggtctaac ttggcaagcg ttgtatagat ctgactgtga tgggcttccc
    11761 aaaaaattgt gatcagctgc ttcaattcat acccagaacg tggtttggat aaaagcacgc
    11821 ataataatat ataggctaaa gtattcataa aaatcctacc tctcgtctta ttttctttat
    11881 tatatcacag taaagtttcc acgttttaca tgtgcatatt gacatgtaaa ataaatcatg
    11941 tatgatgcta atagagagaa agggatggaa atattggaga atcaaataga tatacaagaa
    12001 caaacaaatg aagaaacaaa ggggaaaagt tcagcgctag ttgtagcagc tacctgtatg
    12061 atcgctttta tgggagtggg tctagtagac ccaatcttaa aaacgattgc tgcacagtta
    12121 aacgctacgc cagctgaaac gaccctgtta tttactagtt acatgttagt cactggtgtg
    12181 gtgatgctat ttacaggttt cttatctagt cggatcggtt tgaaaaaaac attgatgaca
    12241 ggattgttta tcatcgttgt attcgctggt cttggcggat tatctgggaa tatcggaatg
    12301 ctgattgggt tacgtgccgg ctggggtgtc gggaatgctt tatttgtctc tactgcttta
    12361 gcaacgatcg tcagtatttt agttggtaac acagaaaaag caatcatgat gtatgaagca
    12421 gcacttggct gcggaatggc tgttggccct ctagtcggtg gggtcttggg cagtggttca
    12481 tggcgttatc cattttttgg ggtagcattt ttgatgtttt gcggttttat agccctagcg
    12541 gtacttttac ctgaaactga gaaaccaaag agaaaagtag gcctttggga aggtgtcaaa
    12601 gcgttaagca atcataaact tcgttcagtt ggactaatcg cattgttata taatttcgga
    12661 ttctttactt tacttgcgta tgcgccattt ttattgattg gctattctga attagaagtc
    12721 ggttttgtat tttttggctg gggtgtgctt ctggctattg cttcgatttt cgttgcaccg
    12781 gctcttgagc ggaagtttac gacttatcgg acaattttag cagcatttgt cttattcatt
    12841 atttgtttgc tgttattagg agctggaact tctatgccag tccttgtacc gatcagcatt
    12901 gtgttagcag gatttttcca aggaattatc aatacactgt tgacgacgat tgctatggaa
    12961 ataccaggtc tgcaacgaaa cgttgcttcg tccagctata gttttgtccg ctttttcggt
    13021 ggagctttag caccatttat tgcaggtgtg attggtgaac atattggtga aagctatgcg
    13081 ttttattttg caggtgccat tgttcttatc agtgtatgtt gtatcattta tcaccgtaat
    13141 tattttgcta caaatgaaga agaataagaa atcagaggtt gtgaaaaagc tgtcctgcat
    13201 caagtcataa gaa
//
LOCUS       DAFLWC010000271        10137 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.guided.098, whole genome shotgun sequence.
ACCESSION   DAFLWC010000271 DAFLWC010000000
VERSION     DAFLWC010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10137
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.guided.098"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            92..988
                     /locus_tag="L1V17_003101"
     CDS             92..988
                     /locus_tag="L1V17_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBN1237766.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(1138..2079)
                     /locus_tag="L1V17_003102"
     CDS             complement(1138..2079)
                     /locus_tag="L1V17_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBN1237767.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            2205..3326
                     /locus_tag="L1V17_003103"
     CDS             2205..3326
                     /locus_tag="L1V17_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBN1237768.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            3584..5086
                     /gene="eat(A)"
                     /locus_tag="L1V17_003104"
     CDS             3584..5086
                     /gene="eat(A)"
                     /locus_tag="L1V17_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBN1237769.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            5114..5680
                     /locus_tag="L1V17_003105"
     CDS             5114..5680
                     /locus_tag="L1V17_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBN1237770.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            5891..6952
                     /locus_tag="L1V17_003106"
     CDS             5891..6952
                     /locus_tag="L1V17_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBN1237771.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            6955..7851
                     /gene="murQ"
                     /locus_tag="L1V17_003107"
     CDS             6955..7851
                     /gene="murQ"
                     /locus_tag="L1V17_003107"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBN1237772.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            7865..9847
                     /locus_tag="L1V17_003108"
     CDS             7865..9847
                     /locus_tag="L1V17_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBN1237773.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(9912..>10137)
                     /locus_tag="L1V17_003109"
     CDS             complement(9912..>10137)
                     /locus_tag="L1V17_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBN1237774.1"
                     /translation="ILTETMREYLEHEDNHKLCLGVVGSGNKNFNNQYCLTAKQYAQT
                     FGFPFLADYELRGTPSDVTRIYQILAENNK"
BASE COUNT         3320 a         1796 c         2212 g         2809 t
ORIGIN      
        1 ttcatacaaa tataggaaac gttttactgg ctttttacta tttaaacagg ctatcatagg
       61 aaaaagtgac agagaaagtg aggcggaaaa gatgaacaaa aatgacgtac tgctagttgc
      121 aaaaaataaa tcactttatt ttttgccttc catccgctct ttagatgttt ggtccggaaa
      181 agatttacta cagtcggaat tcattaaatc agctagacaa cagttggcaa attatcagct
      241 gatcgttttt ttagattatg gatttgatat ggagatggct cgacgcgtgc gcccatttac
      301 caatgcaaaa attgtgttat ttttttggaa tcacttcaaa gcagaacacg aggcgatgct
      361 gaagcaggca caagatgaac cggcaatcga tgagatttat cattttgatt ttttggaagc
      421 aaaagaactt gggctgaaac ataatagttc attttattcg aaacatatga atttttcttc
      481 tagcgaacca aagacggatc tattttttgg tgcaacgaat aatgggagaa aagaacgagc
      541 agaaagctat aagcaggaat ttataaaaag agatgttacg accaactatt tcattcttcc
      601 acatcgaggg aatgaacaac ctggatatct tacttatgaa gagtacctga aaaaaacagg
      661 ggaatcgcgc gggattctgg aactgttgcg ggagggtcag caaggagtga ctttgcggac
      721 atttgaatcc atgtattttc aaaagaaact agtgacggat aatcaagcga ttgctcatta
      781 tcatttttat cgtcctgaaa atattttttt gcttcgagaa cgtgatttag atgaattacc
      841 ggaatttctg catacaccat ttaagccaat cctatcagag ctattggaat tttatgatgc
      901 agaaaattgg gcaaaacgat ttatcactaa cgattccact atttatgagc aatacgaata
      961 tgacctctcc tctgttgaaa acaaataaaa aacctacatt ttgaagagat tatgtactga
     1021 aacaaacaag cacaattctt atggcatcat gagagttgtg ttttcttttt gatcttttat
     1081 tgggcttaaa aaaagagaac cagctgctga ttcagctgat tctcatcaga gagcctttta
     1141 ttctgcgcca aggattcctt cttttgcatg gactaattgg gtcaaaaagg cacaatatgg
     1201 tgtagcaata tcatattttt gtccttttcg ccaaatggca ccattgatgt agtcgatttc
     1261 agtcaaacga tggtttttga tcaggtcttg gtacatagat gggtaatgca acccgatgtt
     1321 gtcaggatca taagtagaag caatatgttg gtacacttct tcttgatcta gtatgattcc
     1381 ttcttttgct gcgatagaag caaattcaga tacgattgtt cgaaccatgc tctctgccgc
     1441 tttttgcgcg cctagttcag caatattaca atccaaaatc gtgcataaac cattcaatgt
     1501 tccatttaca caagcttttc gccaaatgga ataacgaacg ttatggctat agatcggatt
     1561 taaatttgct tcttgaaaga cttctacaac tttttttgta aatgcttcgc cttctggttc
     1621 caagttctct agttcgattt ctccatcacc taacaatgtg acttttccgg gaccagctag
     1681 accagctgtc cacatcgtga tcccaaataa gatatttttc tttggcacat atttttccag
     1741 tacatcttca tgacctaatc catttagtaa acacaaaaca taagtattgt cagtaataat
     1801 ggattggatc gaacaaaaca tatcatctaa ttgattggct tttgttaatg ctacgatcaa
     1861 gtccacgtgt tcgttgcttt cgatgatttc ttctggtgaa tagattggca gttttgcgac
     1921 cacttcttta ccgttaaagt cagcaatcaa cccatttgta cgaatggctt caatgtgagc
     1981 aggccaacga tcgatcaaga ggacctcatt tccgctttga tgtagcatca atccgattcg
     2041 gctgcccatt gctccggccc cagctattgc gattttcatg ttttttctct cctttattca
     2101 atgagttccc ttttagtata tagaaaaatg gaagaaaata gcattgtttt gtttgaaaaa
     2161 aatgaaaaaa agtgtcttac ttaagaagaa agtgagggat acagatggat attttggcgg
     2221 caattgattc atttaaagga agtgcttctt catttgaact aaatcaggca gttctaaatg
     2281 gctgggaaga tcgtaaagga agaaaaatca atgtgccgat tgcagatggc ggagaaaata
     2341 ctgcagaagc aatctattac gcgctcaggg gaacatggcg taccattgat gggatggatc
     2401 tcttattccg tcagcgaaaa atcagctatt tattgacaac ttggcaagga aaaaacaccg
     2461 cagtcatcga atctgcacaa gcattggggt tagatctact tgataaacca acggatcaaa
     2521 ctatccgact tgcttccagt tatgccttag gagaacttat taaagatgca ctgcttcaag
     2581 aagtagaaca aattattgtc actttaggag gaagcgggtg tagcgatggt ggtctaggat
     2641 tactccaatc cttgggtgct tctttagaag ggtacacaga aggaaatcct ttattatcta
     2701 ctaaaaaact tcattttgat cgaagaaacg ttcttgtttc taaagtaaaa ttgattatcg
     2761 ctgcagatgt taccaatcca tatacaggtc aacaaggagc tgcttggcaa tttggaagac
     2821 aaaaaggagg aatagatacg acgctagctt tcttagataa acaagcagga aagattgctc
     2881 agcaaataaa agatttctgg gaggtggatt tagatgatat tccaggaagt ggagcagcag
     2941 gcggtattgg tggagccctt tttttgttgg gagcgaagat ggtttctggt ttcgatttag
     3001 tcagccaaat cactggattg gaaaaaaaga tcgaacaagc agatgtcatc attacaggag
     3061 aagggcggat cgatcagcaa acgatccacg gaaaagttcc atacggtgta gcagtgcttg
     3121 caaaaaaata tcgaaaacca ataatcgcta tttgcggaag tagagaccaa gagctagaag
     3181 gactttctga ttttctccca attgtcttaa gtattcattt gggtccaata ggtttagaag
     3241 aagcaatgga acacaggcaa acattagaaa aaacaaaaat cttaggacag acacttagca
     3301 gatttttcac catcctcccg aagtagttga caaaatcatt ttctttatgc tatcgtaatt
     3361 tcaaatatag gacaaagtga gggatccgtg cattgaaaaa ttaagtcgat tgatgaaagc
     3421 tgcattcaga ctgtaccttg tggagacaag gaagcagtgt gcagattttc gggattggct
     3481 tggttttttc gatgtatggg tctttttgtg tgtatccaac ccttgcatcc tctttagcca
     3541 gttctgaaaa taggactggt ctttttttac gaggtgatgg aaaatgtcta aaatcgaaat
     3601 aaaaaatctg acattcggct acgacagcca aggcacatta ttatttgaac aagcaaatct
     3661 aaattttgac acacaatgga aactaggact tatcggacga aacggtcgag gaaagacaac
     3721 tttactgaat attctacaaa acaaactacc ttatcaaggg caagtaatcc atcagcaaga
     3781 atttgcctat ttcccgcaac agacaaaaga taaagaacgt ttaacctatt acgtgttaaa
     3841 tgatattacg gattttgaga tatgggaaat cgaaagagag ctccaattga tgcaaacaga
     3901 tcctgaaatc ttatggagag aattcagcac actatcgggg ggagagaaga caaaagtcct
     3961 actggcactt ttatttgtgg atgacactca tttcccgtta atcgatgaac caacgaatca
     4021 tttggatatc tctggtagaa aacaagtagc ggcttatttg aaaaagaaaa aacaaggctt
     4081 catcgtggtc agccatgacc ggggatttat cgatgaagta gtggaccatg ttttagcaat
     4141 cgaaaaaagt caactggaac tttatcaagg gaatttctct atctatgaag aacagaaaaa
     4201 acttcgtgat gaatttgaaa tggctcaaaa tgaaaaattg aaaaaagaag tcagtaggct
     4261 aaagaaaaca gcagctgaaa aagccgaatg gtctcgttcc cgagaaggag ataaaacaaa
     4321 gaaacaagtc ggattcatcg atactgaatc tagacgagtg aataaaggag cagtgggtgc
     4381 tgatgctgca cggacgatga aacgatccaa agcaatcgtg aatcggatgg agacccagat
     4441 cagcgagaaa gaaaaactat taaaagatat cgaatatatc gattctttga cgatgaatag
     4501 ccaagcgtct caccataagc gacttttaag cgtagaagat cttcaattag ggtatgaaaa
     4561 tctgttattc gagccaattc attttacaat cgagcctcat cagcgggtgg cgatttcagg
     4621 tcctaacggt gcaggaaagt catccattat ccattatctt ctgggggcat tcaacggcaa
     4681 ggttatagga gaaaaatacc agccaaaaca tctgagcatt agttatgcaa gccaaaatta
     4741 tgaagacaat cgaggaacgt tggcggaatt tgcagagaaa aaccaagtag actaccaagc
     4801 atttttgaac aacctccgaa agcttgggat ggaaagagat gtttttcata acaagatcga
     4861 gcagatgagt atgggccaac ggaaaaaagt ggaattggct aaatctttat cacagccagc
     4921 tgaactatat acatgggatg aaccattgaa ttatttggat gtcttcaatc aagaacaatt
     4981 agaacaactg atcttgaacg tgaaacctgc catgttacta gtggaacatg atcaaacctt
     5041 cctggataaa gtatctactg agattatttc tcttgagaga atctaaccct tgtaatctca
     5101 agaacaacaa ggtatggtta aggggaactt tgccaacgaa ggagagaatc acatgcttta
     5161 tgtaacgaga cacggagaaa caacttggaa cgcacaagga ttagtttgcg gacgggcaga
     5221 tgtgccgctg actgaaaaag gacagatgca ggcacagaaa ctagcagaaa aggtagtaga
     5281 tttgcctgtt ccaatcacga aaatcatcca ttcccctctt caacgagcaa gagatacagc
     5341 acaagcagtt gctgatcgtc tcagcttgcc gctgaccgtt gatgaacgat tggtagaaat
     5401 ggattttggg gattatgatg gactgccaag caaagatgag aactttcaaa aagcacgttt
     5461 agcgttcgct gtacgattcc caaatgggga gtcagtctta gatgtgtatg cacggatcgt
     5521 tcctttattg aaagaatgca tcgaagacga agaaaatgtc tatctgttag tttgccataa
     5581 tgccttgata agagtgatca atgcttattt tcatccgatg cctaatgagg ggttctttac
     5641 attcatggta gataatacag aattggtttc ttatgagtaa ttatgttttt gtgttattta
     5701 aataaaatat ttcaaggcac tgcttttgct tagcagtgcc ttttttaggt tatgacaatt
     5761 cttttgataa tataaactca acctttagaa atgaaattta attattttaa taaaagtatt
     5821 gaaattttgt ttctttagat atatactcta gtcatagaaa tgaagacgga tacagaaaaa
     5881 gagggataat atgtttggct tttcaatatt tatgaacgat tctttgtcag aagagaagaa
     5941 acagtatatc cgccaaatgg catccaatgg ctttgtcggt attttcactt ccatgcatat
     6001 accagaagat gatgtttcgg catatcaaaa gcgattgatc gaactaggaa gcgaagcgaa
     6061 aaagaataaa ctagaattga tggtcgatat ttcaggagag gcattggaac gagcgggttt
     6121 ttcattagaa gatctaacgc ctttgaaagc aattggtgta acaggtttaa gaatggatta
     6181 tcatatttcc aatcagcaga ttgccgactg gtcacatcaa ttgaaaatca gtttgaatgc
     6241 tagcacgatc acgcctaaag atatcgatga attgaaagaa gcagaagctg atttctcaca
     6301 gattgaagct tggcataatt attatccacg tcccgaaaca gggctggaca aagaatggta
     6361 tcagaaaaaa aatcaatggc tcaaaattca aggtctcctt gtccaaggtt ttgtaccagg
     6421 agatacagag ttgagaggcc cactatatca aggattgcca actttggaag aacatcgagg
     6481 gatccatcct cttgcaggcg ctctagatct attagcaagt aacacggata ttgtttacat
     6541 cggagatgca ggtctgtcag aaaacgttca ggagcaattt gcttctttcc aaaaagaaca
     6601 gacagtcttg ctccatacgg aacctgtaga tgaagaattt tacgaatata tattagggaa
     6661 gcatacgaat cggcaagacg atgcaagaga tgtcatacga agcgtagatg cacgttttcg
     6721 agagattccg cctatcccag caagaaatac agctacgcgt atgaaagggt ctattacttt
     6781 agataacgaa aagtatttgc gctatatggg tgagatccaa ttaaccaaat atgatttgcc
     6841 agcggatgaa aaagtgaatg tagtagctaa agttatcaaa gaagagctac cattgatcaa
     6901 ccaaatcaaa gctggtatga actatcaatt tataagaaaa gaaggaagat aaaaatgagc
     6961 aaaatcaatt tagagaacct aacaacggaa cgcagaaacc aagaaacttt tggattagat
     7021 gagatgagta tttctcaagc cgttcaacta atgaacaaag aagatcagaa agtggccgct
     7081 gcggttgaaa aagaactgac aagtatcgaa ccagtgattg ctaacacgat tgagtccttt
     7141 aaaaaaggtg gacgtctgat ttatatggga gccggaacaa gtggaagact aggtgtgtta
     7201 gatgctgctg aatgcgtacc gacattcggt gtagaaccgg aaatggtcat aggtctaatt
     7261 gctggtggag aagaagcaat gactgtagct gtcgaagggg ccgaagattc ttatgagcta
     7321 gggcaagaag atctaatcaa gctgaatttg acaaaaaatg atatagttat tggtatcgca
     7381 gctagcggtc gtacaccata tgtgatcggt ggattagatt acgcaaaatc gatcggtgct
     7441 gtcacaggaa cgatttcttg caataaacaa gccgaaatca gtaaacacgc ggatttccca
     7501 atcgaagtcg atgcaggtcc agaatttttg acaggctcta ctcgattgaa gtcaggaaca
     7561 gcacaaaaac ttatcttgaa tatgatttct actatcagta tgattggtat aggtaaagta
     7621 ttcaataact tgatggtcga tgtcaaacca acaaatgaaa aactaatcga acgctcaaaa
     7681 cgaatcatca tgcaagcgac agaagctgat tacgaaacag ctgaaaagta ctttgaagaa
     7741 gcagatcaaa atgttaagct ggctatcgtc atgattttga caaatagtga taaagaggaa
     7801 gctcaagcaa aattagctga agcaaacgga tttgtaaaag ggaccttatg agggggaaaa
     7861 gaccatggca aaaaacgaac tgactttgga agaactggca aaacaaattt ataaaggggc
     7921 aggcggcatg ggcaatgtag aaagcattgt ccactgcatg actcgtgtgc gtatgaagat
     7981 catcaatgat gatcttgtaa atgtctctga attaaaagcg attccaggag tgcttggtgt
     8041 agtagaagat gaacagcttc aagtcatcat cggacctggg aaagtgaaca aagtagcaca
     8101 gcaaatggtt gatttggcag gcgtgaaatt aggagaaaaa ctttcttctg taagtacagc
     8161 tacagcaaat tcatcagcat ctggaaaaga ccgtgtaaac gaacgggcac aagaaatgaa
     8221 agcggcacaa aaatcgaaac aaaaaccatc taaaatcaaa tcggtattaa aagacatttc
     8281 taatatcttt gtgccaatga ttcctgcatt tgtcggtact gggatcgtgg cagggattgc
     8341 cgcagtttta gcaaacttag tcacagccgg aacacttgat gcagcaacat ggcaacaata
     8401 tatcgatgtg atgaacatct tgaaaaacgg gatgtttagc tacctagtta tctatacagg
     8461 tatcaatgct gcacaagttt ttggtgcaac accaactctt ggtggagtta tcggggccgt
     8521 tgtgatgctg acagggatga atccggaagc accactgaaa aacttattta ctggtgaagc
     8581 tcttgcagct ggacaaggtg ggatcctagg tgtcatcttc gctgtttggc tattgtcaat
     8641 cgttgagaaa aaactgcata aagtagtacc tgatgcggta gatatcatcg ttacaccaac
     8701 tctttcattg attgccatcg gtctgattga aattttcttc atcatgcctt tagcaggttt
     8761 catttctgat ggcatggtcg gtgggatcaa ctgggtactt ggcgttggtg gagcatttgc
     8821 cggcttcgtt ctaggcacat tattcttgcc gatggttatg ttcggactgc atcaaatttt
     8881 gactccaatc catgtgcaaa tgattgatga aactggtcgt acgctattgc ttccaattct
     8941 tgcgatggct ggtgcaggac aagtgggtgc agcattggca ttatggattc gctgcaaaaa
     9001 agataaagaa ttaacagaaa tgatcaaagg agctttacca gtcgggatcc taggaatcgg
     9061 cgaaccattg atttacggag taacattacc tctaggacgc ccatttatta ctgcttgtat
     9121 cggtggaggt atcggcgggg cagtgatcgg aatgatcgga aatgtcgggg ctatcgctat
     9181 tggaccttca ggagccgctt tgatcccatt gatctctgac ggtaaatggt taggctacat
     9241 ccttggatta ttggcagctt atgctggtgg cttcgttgct acattcttct tcggtattcc
     9301 taaagaccgt ttagaaaaag aagaattagc gactgaaaca gccacagtaa atgaagtgcc
     9361 tgaaaaagta gtacctcaaa cttcagctga aagtgtgact atcctctcat cagttgctga
     9421 cggaacagtt gtttctttag ataaagcaag tgatccagtt tttgcacaaa agatgatggg
     9481 tgaaggctac tttgtagaac cagaaaacgg acatatctat tctccagtta ctggggtagt
     9541 cagctctgtc ttcccaacga aacacgctat tgggatcaca acgccaaatg gtttagaaat
     9601 cttgcttcat atgggaatca acacagttga cttaggcggt acgccatttg atgtgaaagt
     9661 aacagaaggg cagcaagtga cacctgatac gcttgtagca gaagctgact tagaagcgat
     9721 caaagcagca ggcaaagaaa catccatgat cgtcttggta accaatatgg atcgtgtaaa
     9781 aaactttgtc ttggaaaaaa caggtaaagc aaaagcaaaa gcacctgtga tggatgtcaa
     9841 agcttaatat gatagaaaca atagaaacga aagaagaaac tgaaatctat ttttcagctt
     9901 cttctttttt attatttatt gttttctgct aaaatctgat aaattcgtgt cacatcagat
     9961 ggtgttcccc gtaattcata atctgccaag aaaggaaagc caaatgtttg tgcatattgt
    10021 ttggctgtta gacaatactg attattgaag tttttatttc cgctaccgac tacaccaaga
    10081 caaagtttat gattgtcttc atgttccaga tattcacgca tcgtttcggt caagatt
//
LOCUS       DAFLWC010000272         7943 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.guided.112, whole genome shotgun sequence.
ACCESSION   DAFLWC010000272 DAFLWC010000000
VERSION     DAFLWC010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.guided.112"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            128..1564
                     /locus_tag="L1V17_003110"
     CDS             128..1564
                     /locus_tag="L1V17_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBN1237775.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKSSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            1753..4185
                     /locus_tag="L1V17_003111"
     CDS             1753..4185
                     /locus_tag="L1V17_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBN1237776.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQLSFVPI
                     DSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQDYELPT
                     VDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEVQPAVG
                     VKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIEAQPNH
                     PDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRAKPHEV
                     KLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAATGVRNI
                     SGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMARAAGI
                     HMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGDMLFLP
                     MGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQPQDELF
                     EEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKVFIEQE
                     ETSETLPDDNDM"
     gene            4415..5482
                     /gene="rlmN"
                     /locus_tag="L1V17_003112"
     CDS             4415..5482
                     /gene="rlmN"
                     /locus_tag="L1V17_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBN1237777.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(5675..6778)
                     /locus_tag="L1V17_003113"
     CDS             complement(5675..6778)
                     /locus_tag="L1V17_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBN1237778.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7330..7878
                     /gene="aac(6')"
                     /locus_tag="L1V17_003114"
     CDS             7330..7878
                     /gene="aac(6')"
                     /locus_tag="L1V17_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBN1237779.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2658 a         1357 c         1724 g         2204 t
ORIGIN      
        1 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacataa ttttattttg
       61 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
      121 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
      181 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
      241 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
      301 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
      361 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
      421 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
      481 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
      541 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
      601 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
      661 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
      721 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
      781 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
      841 aaatgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
      901 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
      961 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     1021 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa
     1081 aatgaatacg acaggaaaaa aaagttcatc agaagaaact ggagttcctg gaatgtataa
     1141 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     1201 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     1261 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     1321 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     1381 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     1441 aaagcgatat ggatttgtat atgttgatca agacgaaaca caagaaggat ctttggaacg
     1501 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     1561 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     1621 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     1681 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     1741 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     1801 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     1861 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     1921 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     1981 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     2041 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     2101 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     2161 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     2221 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     2281 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     2341 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     2401 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     2461 gcaaaagaag ctgcagaata tgagaagaaa aaagcggtga gccagcaaag ggaaaatact
     2521 gctgatgaat ggcaggaacc agaaaataca gagccggagc agctaagttt tgttccaatc
     2581 gacagttttc aagaaaatat ccatcctgcg aatctagaga aaccagtacc agatacacca
     2641 aaacagacca atacagcaga aggtttttca gatgagttgc cagaggatga cggtacctca
     2701 ttagaatttg agattgaagc agaacaggaa aatcaagact atgaattacc gacagttgat
     2761 ttgcttgatt ctataccaac tgtggatcaa agtgatgagt ataaaaaaat tgaaaaaaat
     2821 atcggcgtat tagaacaaac tttccaaagt ttcggtgtcg atgccaaggt cgtcaaagcc
     2881 agcttaggac catccgtcac aaaattcgaa gtccagccgg ctgtaggggt aaaagtaagt
     2941 aaaattgtga acttaacaga tgatatcgcg cttgctttag cggcgaaaga tgtccggatg
     3001 gaagcaccga ttccaggtaa atcactgatt ggtattgaag taccaaatgg aaagatcagt
     3061 atggtttcct ttagagaaat catcgaagca caaccaaacc acccagataa attactagaa
     3121 gtacctttag gacgtgatgt ttctggacgg gtacaaacgg ctgatctttc gaagatgcct
     3181 cacttactcg tggctggttc gactggtagt gggaagtcag tagcaattaa tgggattatc
     3241 acaagtatat taatgcgtgc taagccccat gaagtaaaac tgatgatgat cgatccgaaa
     3301 atggttgaat tgaatatgta caacggcata cctcatctgt tgacgccggt cgtgacgaac
     3361 cctagaaaag cagcgcaagc cttacaaaaa gtagtacaag aaatggaaga acgatatgaa
     3421 aaattcgcgg caaccggagt aagaaatatt tctggttaca atgaatttgt tcaacagaaa
     3481 aacttggaaa acggaacgaa acatccaacc ttaccattca tcgtagtgat cgtagatgaa
     3541 ttagctgatt tgatgatggt agccagcaat gaagttgaag atgcgattat tcgtttagcg
     3601 caaatggctc gggcagcggg gattcatatg atcctagcta ctcaacgtcc aagtgtggat
     3661 gttatcacag gaatcatcaa agcaaatgta ccttccagaa tggcatttgc ggtatcaagc
     3721 ggtacagatt ctcggacgat cattgattct aatggggcag aaaagctctt agggcgagga
     3781 gatatgctat tcttgccaat gggtgagaat aaaccgatcc gtgtgcaagg agcattcatt
     3841 tctgaccacg aagtagaacg ggtcgttcaa tttgttacag atcagcaaga agctcattat
     3901 gaagagaaaa tgatgccgac agatgaagtt gaaacgacag gtgctccaga acagccacaa
     3961 gatgagctgt ttgaagaagc aaaagcactt gtcgttgaaa tgcaaacggc aagtatttcc
     4021 cttctccaaa gaagatttcg gatcggttac aaccgagcag cacgtttagt agatgaactg
     4081 gaagctcatg gagttgttgg cccgtcagaa ggaagcaagc ctcggaaagt attcattgag
     4141 caggaagaaa catcagaaac gttgccggac gataatgaca tgtaaaactt gtgtgatgaa
     4201 gggttgaaaa acgaataacc aataaaaaga caaggcatga tgataccaaa agaaaaaatg
     4261 gtttttttcc atcttttcta atacggtatg atgtcttgtc tttttagttt ttgtgagatt
     4321 aaagttctat tcgatttatt tgtgaagtat tgcattaagg aaatgaatca tgtatagtat
     4381 gtagcgaaac tttgagaaaa agagggaaaa tactttggaa aaacagtcca tttatggctt
     4441 gacgaatgaa gaattaatca attggtttat agaaaacggc gagaaaaaat tccgagctgc
     4501 ccaagtttgg gaatggttgt atcaaaaacg tgtaagtaat ttcacagaaa tgacgaatct
     4561 atcgaaacaa ttgatcgaaa aattatcgga gcattttatc atcaatcctc taaaacagat
     4621 ggtcgtccaa gaagcttcgg atggtacagt aaaatatttg tttgaactcc ctgataaaaa
     4681 catgattgag actgtactga tgagacaaga atatggcttg tcagtttgtg tgacgacaca
     4741 agtaggatgt aatatcggct gtacgttttg tgcaagcggg ctgctcaaaa agaaccgtga
     4801 tctgactgct ggagaaattg ttgcacagat catgatggtc caacattatt ttgatgagcg
     4861 caatcttggc gaacgcgttt cacatgtcgt tgtaatgggg atcggtgagc catttgataa
     4921 ttacgacaat gtaatggact ttttgcatat catcaatgat gccaaaggat tggcaattgg
     4981 tgctcggcac attacagttt ccactagtgg attagcacac aaaatcaagg aattcgctaa
     5041 taacggcttg caagtcaatc tggctatttc cttgcacgcg ccgaataatg aggtgcgaac
     5101 atcgatcatg cggatcaacc gaagtttccc aattgagaaa ttgatggaag ctgtggatga
     5161 gtatttagag aaaacaaacc gtcgaatcac gtttgaatat atcatgttga atcaagtaaa
     5221 tgatagacca gagcatgcgc aacaattagc agatctatta aaagataaga aaaaattagc
     5281 atatgtcaac ttgattccat ataatccagt cagtgaacat gatcaatatt ctcgcagtcc
     5341 aaaagctgat gtattgagat tttatgatgt attgaagaaa aacggcgtaa actgtgtgat
     5401 acgtaaagaa catggtacag atattgatgc agcttgcgga caattgcgaa gcaagcaaat
     5461 gaaaaaaaca gttgccaaat aatcgtatcc tactcgtttt ttcaattacc ataaaaggag
     5521 cagttttctt aattaaggaa ctgttcaact taaataagag aaaagattct atagcgaaag
     5581 ctataaagct ttttttgaca agaaaaaccc tcatcaagca aagaaatgtc ctcaatttga
     5641 tgacagcctg cttgatgggg gttttagcaa ttatttaact gattttctta tatccttgct
     5701 ggctttcttg tgtagcatga taagtttcta cgtcaagaat ggcctgttta aatttttctc
     5761 gggtgatttc ataaggcaca tgtttaatat catttgttgc catggcttta tctaagattg
     5821 cttctaaatc ggtcgtgaca ttgagattca tgtcggttaa cgatactgga agttggttct
     5881 ttttcataaa cacatagatt ttatcaaaca aatcgaactg ctgatccatc atcaataagg
     5941 tcagtacacc ataactgaca gatgctccgt gaaggtatcc ctccattttt tctagaacag
     6001 tcgtaccgta atagaatgag tgtgccatag cagaattata gttattgtta actaaaacag
     6061 aaaccaatcc ggtagtaaca atgatatccg aaacgacttg ttcaattgca tatgagggac
     6121 gatcgtcggc actatctttc aatgcttgcg taccataagt caagagacga tcaatgcaca
     6181 tttttccgat ttggattcct aatctatccg tgtagcctag atcatcgcca cgagcagaaa
     6241 aagtagattc gacttctttg gataaagcat cgccaatacc tgcccataag tatttatcag
     6301 gtgcttcggc aataattgct gtatcaatga aggtgtgtac aggtggtttt gaaggaaaga
     6361 agagtccgtc cattacgcct tcttcgttat agatgacaca taccgcagtg acgggcgaac
     6421 agttcgaacc aatagtggga aaggtgaaga ctggtttagc tagtttttca ccaatgactt
     6481 ttacagtatc gcaagcacgg ccaccaccga ctgcaaacag gacgtctgct ttttggacac
     6541 tttcatgctg gatcaactgt tcaatatttc cataagttga attacccccg taccagagac
     6601 tggcgacaac ctctatttcc tgtgtcaaag ctacttttat tttgttttct gcctttgaaa
     6661 gtgcagtctt ccctccaatc agcactactt ttgtcccata ttctttgacg attccatttg
     6721 ctttttcata cgcatctgtt ccaatggtat aatttggtaa gaaaacactt tgactcatat
     6781 tcatttcctt ctttcttcgt tgaaacgggt taaaatttta aagagtgatc gatctgactg
     6841 cggctgtaga tggagtagag gtgaacctaa gacaggataa gtgatgaata aggtggcatg
     6901 aacaccttga aatcatcaat aagtatccta aaaacgaaca agtacaaaaa cattgaaaac
     6961 gacaataatg aatttttgtt cctcttagta tttctaccga ttccctttgc ttttttgtaa
     7021 ttatctaaaa attctaaaaa ttaagattat tatatgaaaa caggttttat ttgtcaattc
     7081 ataattggtt ttttttaaag caaaagataa tctatatcat gatgaacaaa cagagttttt
     7141 tcctccaatt gatggctttc ctgatctttc ctattttgaa taaagtgttt ctgtataatt
     7201 ttttatttta taagtaagat aaataatgaa agaatagaga tactgattgg tagctaaaga
     7261 tttttgagcg agaacatttc gttttttcaa aaggactgtt agaataagca agaacaaggg
     7321 ggaagacgta tgataatcag tgaatttgac cgtaataatc cagtattgaa agatcagctt
     7381 tctgatttac tgagactgac ttggccggaa gaatatggag acagctcggc agaagaagta
     7441 gaagaaatga tgaatccaga acgaatcgcg gtagcagcgg tagaccaaga tgagttagta
     7501 ggatttattg gtgcaatccc tcaatacggt atcacaggtt gggaattgca tccattagtt
     7561 gtagaaagct cccgacgaaa gaaccaaata ggtactcgat tagtcaatta cttagaaaaa
     7621 gaagtagctt ccagaggagg aatcacgatt tatttaggta cggatgattt agaccatgga
     7681 acaacgttaa gtcaaacgga cctgtatgag catacatttg ataaagtggc ttccatccag
     7741 aaccttcgtg aacatccgta tgaattctat gaaaaattag gttataaaat cgtaggtgtc
     7801 ttaccaaatg caaatggctg ggacaaaccg gatatttgga tggcaaaaac gattattcct
     7861 cgaccaaatt ctcaataata aaaagaggtt gtgacagaag taatcagctt caagaaataa
     7921 gaaggaattt acgaaaatta ctt
//
LOCUS       DAFLWC010000273         5643 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.guided.131, whole genome shotgun sequence.
ACCESSION   DAFLWC010000273 DAFLWC010000000
VERSION     DAFLWC010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5643
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.guided.131"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            114..806
                     /locus_tag="L1V17_003115"
     CDS             114..806
                     /locus_tag="L1V17_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBN1237780.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSWKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
     gene            1133..1630
                     /gene="dfrG"
                     /locus_tag="L1V17_003116"
     CDS             1133..1630
                     /gene="dfrG"
                     /locus_tag="L1V17_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HBN1237781.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(1702..3654)
                     /locus_tag="L1V17_003117"
     CDS             complement(1702..3654)
                     /locus_tag="L1V17_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HBN1237782.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3661..3897)
                     /locus_tag="L1V17_003118"
     CDS             complement(3661..3897)
                     /locus_tag="L1V17_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237783.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            4299..4589
                     /locus_tag="L1V17_003119"
     CDS             4299..4589
                     /locus_tag="L1V17_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237784.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            5303..5605
                     /locus_tag="L1V17_003120"
                     /pseudo
     CDS             5303..5605
                     /locus_tag="L1V17_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1915 a          905 c          982 g         1841 t
ORIGIN      
        1 gtatttgata gtatttatat taaaattaca tatgtaattt aaaaacgctt gacattgtgt
       61 ttgagatcac ttacttttag catgtaaaag tattggatta aggagctatg caaatgaaaa
      121 agaaatttat tactggtggg attgtcgttg catttctatg tctaattggc tacacaggca
      181 cgcggtacgc aaatgaaatt attttgtggg gtggagagac agatattgat acaatcaatg
      241 agaatctgac acagcttgat catacattga cagataaaga gcaagcgatt acagatctta
      301 ccgctcgact agcacaaaaa gaacagacat tgcaagattc aaaggcagat gtccaagaat
      361 accaaacaaa agtaaatgaa ttagaaaacc aaaaaaatca atcggcagca gaaaaacaaa
      421 acttagaaag tcaattagtc agcaaggatg cacaactaca aagcaaacaa aatgaaatca
      481 atgtcaaact agatgagatc aaccaaaaaa atgatgaaat caatcatctg aatgcagatt
      541 ggacagcaag actacaagaa gcacaagcaa aactttcaga attacaaaat actgtaaatg
      601 gtttgaatca acaaatcgca acactgacac aagaaaaaac aaatgtagaa actcagttaa
      661 cagatacaca aaagaaatta gacgaagcaa ctgctgaaaa ctcaagctgg aaacaatata
      721 ttcaaaagtt agaaaaagca aaagatgaag tggaagatac agctgataaa tctcagcaaa
      781 ttgttgaaga acatttgcgt aaataatctt tcttaacaag taaacctaaa ttagtaaaga
      841 agcaacagta atctatacta agtagttcag ttttggagta caaaatgaca aaatgtactt
      901 caaaatggac tacttttttc attttaactt acataccaaa ttacatacaa aatgatttat
      961 aaaatgcaat tgaaaatgat aattgaatga aaatttgtga ttttgtggta ttatgataat
     1021 ataacttata gaaaaaattg cttattcaac taacgggcag gataatgaga aaaggttttt
     1081 tgatagaaat aagaaattag atggtaaatt agttaaaaag gctgtgttat aaatgaaagt
     1141 ttctttgatt gctgcgatgg ataagaatag agtgattggc aaagagaatg acattccttg
     1201 gaggattccc aaggactggg aatatgttaa aaatactaca aagggacatc cgataatatt
     1261 aggtaggaag aaccttgaat caatcggaag agccttacct gacagaagaa atattattct
     1321 gacgagagat aaggggttta cctttaatgg ttgtgaaatt gttcattcaa tagaagatgt
     1381 ttttgagtta tgtaaaaacg aagaagaaat ttttattttc ggaggagaac agatttataa
     1441 tttgtttttc ccttatgttg agaaaatgta catcacaaaa atacatcatg aattcgaagg
     1501 agatactttt tttccagaag tgaattatga ggaatggaat gaggtatttg cccaaaaagg
     1561 gataaagaat gataaaaatc cgtataacta ctattttcat gtatatgaaa gaaaaaactt
     1621 attgagttaa cgggtgcgtt aattgaagaa gaacagtaaa gataaagcac aagagcttgg
     1681 gattactcca agctcttttt gtcatttgaa ataaattata tctttccaat caaattgttt
     1741 atctgtaatc cctaatcttt gagcaggtgt caaaaccttt ttatccgctg atttaaaagg
     1801 gcgacaaaag ttgtagtaag ttcttagaat tgtaatcgca aattgagcat acttcggatt
     1861 gaagttagcg taaatatagc tcttcttatc accacgagct gttgttaatg gtctttcaag
     1921 agatgatata taacgtctta tctgttgaat aaagctattg gtcgaatggt cattaacatt
     1981 taatagcatc tttgcgattt cgtttggttc cagagcagat aaatccgttc tacaatcaac
     2041 tgaataaaat cctttatcct tagtggctaa tggatgtttg atagggttat cggcatattt
     2101 gcgatatctt tctccatctt tactaatagc ctcttcgtgg aattgatgac ttgttagtaa
     2161 ttcagttaga taatgagatg ccaaagtccg tagaaacttt gttttgaatc ctctgatatc
     2221 tccccaatcg agcagttctg cttttgcttg tccgaattct tttaagcatt gttttctgct
     2281 tttcgtcttg ttaacttggc aaataaaatg atgtgcatcg ctcaacctta attctttcgt
     2341 gaatactcta taaaaggcgt ttctaataga gaagtcatca tcactaatca ttcgccattc
     2401 gtcggcatta accatttgtt taattaacca atagtgagca gttgtagtat aaggagcatc
     2461 aacatttaaa ccatcgacaa atctactcct attagtaatt ttccctaatt cgtgaagata
     2521 agcattccta ttttcgctat cgttagcgga tggttcttgt ggataataag accaatctaa
     2581 cctatcattt ttacgactaa aagtattgag atggtcttct ttgaattttc ttgtatcttc
     2641 atttaattca tccattgaaa tattccaatc ataggcaaca tcagaacgga acacatatct
     2701 tgataagacc tcagcagata caactatata cgtttgcata ttaaggtctt caaaccccgt
     2761 atatttcttt gaaccttgtc ctttcttacg gacgttattt aggtagtagt gcatcttgtc
     2821 cgtattaagc cacatctcgt taaatttctt tgtttgaagg ggttgtgtct catatcgttc
     2881 taaaaactcc aaacaacgcc tatacagcca ctccagctta tgatagtagg ttccaactcc
     2941 aattcctaaa atatcacaag tacgactgac tgaaaccctt ccaacaacca tcttagcgaa
     3001 cattggaaga atggtgttct tttgttggtg ataagtagtg gtttcttctc tttttggtag
     3061 aacattagtg aacttcttac acgccttaca ttgatagcgt tgagatttgc ccctactttt
     3121 cccccttttg taaaattgct tcggctcatt gaatggggtt gattcttctt ccgagcagcc
     3181 ttctttatga aattgataat ctggctcaac atcttggatg ctattgattt ctataaggcg
     3241 tttaatttct tcaacaacag accaattaga taaaggggtt actgtacagt tttgcgatac
     3301 acctctgcca ataggattgt cattgcagta cataccttta tgacctttat ctttggaact
     3361 accagtcatt ttatatcgac ttggtttccc ttttacatct ttgaatttgt gctgttcttt
     3421 cccaaaatta caacaaaacg gattgatgca gtaattatat tgaatgggat attcagaacc
     3481 gttccattta aaagacgttg gcaagaacaa cattttgtta taccttgttg caaatcgttt
     3541 tggagttaat aaatcatatt gtttagccct atcttttaat tcttcgtttg aaatcggaat
     3601 tttaacatct acaatttcat cttccttcgt ggctaatctt ttaagcttgg tcattgtcta
     3661 tcaacccact ctatctttga tacccatttt ttcaacaatc cgcttattac ttcgcttgtt
     3721 ggcaatccat tcaataaact tcttatcgtc taaaatgttc aataagaatt catccactgc
     3781 ttcgctttca gtacgctctg catattcagc gtattgctta actatcaccc ttacttgctc
     3841 tgatatttcc caatccacag acttagcgtt cttatttttt ggctcaagaa attgcatagg
     3901 aaaatgcacc cctttttgct tagtaaattg taaccatttt aacacaccaa tttgcattcc
     3961 tacaataatt atttcacgtt cgcattttta tatacatttt aacttacatt ttgtggtgta
     4021 aattaacaac aaacgttgat ttaacaataa aaaacgagta tcaaattcag ttgcaatttg
     4081 atactcattt aggtttacat tttcactttt tgtactccaa aactgaacta cttaaatcta
     4141 tactgctgcc tctttttttt agtacatgtc cttcatcttc gcaggaagtg ccaatatgat
     4201 tttaagaaag gtaatagaca aaaagtcaaa aagataaaac agagtttctt ctttacaaag
     4261 ggaatgtatg ttcgtataat ggtattgagg tgaaggttat ggagaaaaaa tatggaacag
     4321 tagataagat ccgtactttg caagttagtg ccagaccgtt gatccgtttc agtttaaatg
     4381 gggtcaattg tttgattgct tcccatagtt tgaacttcct agctgaagta gacgaaggga
     4441 tgaagttagt cgttacaggt tattataata atagaaagca atttgttgtg agatcctatc
     4501 atgtgttagg gaaacccaaa attgtggtag aatatgagaa aagtctatac ccaagaaaaa
     4561 aggtccgaca agatgaaaga ataaactaga aaacaagcgg ctgagacaaa aatgtcctag
     4621 ccgcttgttt tggaaagatg gatgcagacg atgggatttg aacccacacg agcatacgct
     4681 cacaagaacc tcaatctata tataactaca tgtatttaag tatttgtgat gaatcactaa
     4741 actttccaaa ctcatttgag ggatattgct taaagattga acagatcaat tcgaagccct
     4801 attagtattc gctcaatggg gggatcagag gccataaaaa gagactagtc attactagtc
     4861 tcaggtagtg gaattgtagg attttaaacg ttcctggaga gtaccggtat gtaactcgaa
     4921 gaggtgatta tcatagtcgt aaaagtaaat tgaagaagcc tcgcctttca cacgagaacg
     4981 tcctggttcg acagttaaac ctaacatttg gatttttgag acaaacgaat ctatatcttg
     5041 ttcgtcaatt ttaaaagcaa tatgattgta tgtctttggc agtttattcg acgaattctg
     5101 cattactgca atccataggt ccttaactaa gaaaaatttt tctggatata atgaaaattt
     5161 ttttgttgac tatcgtagat ttcttttgca tcaaataagg tatttaacaa ttaagtattt
     5221 aaaagataac ttttaagtta tctttaagta atgcttaaag ctatgttata ctctattagg
     5281 aaatataaga aggagtataa aaatgaacaa acataataga aaaataacga ataacaaaga
     5341 actgatcttg ttactaatag ggatttgggg tatcttttta ctctttaata tgtatatgcc
     5401 gactatgaga gcggatgacg tagtttatgc aagtagatta gatgaacttg gctatttggg
     5461 tgcttcgata gaacattata agacatggag ttcaagaatt attatagaac tattcttaat
     5521 gttcttttct aaacacttta tgctatggaa attattaaat tctacgatta tgttaggaat
     5581 tgtagtatta ctttgcaagt atgttgagag tataaaatat tttgtgtaaa tgaaaaaatc
     5641 cat
//
LOCUS       DAFLWC010000274         4702 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.guided.141, whole genome shotgun sequence.
ACCESSION   DAFLWC010000274 DAFLWC010000000
VERSION     DAFLWC010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4702
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.guided.141"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            194..1000
                     /locus_tag="L1V17_003121"
     CDS             194..1000
                     /locus_tag="L1V17_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-B"
                     /protein_id="HBN1237785.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGWR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            1018..1725
                     /locus_tag="L1V17_003122"
     CDS             1018..1725
                     /locus_tag="L1V17_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBN1237786.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGETFSFWLFLHTP
                     LTIIQRRGHEVKEFPEPNSDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKII
                     GQVFADKEPQALYKITNGSIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKC
                     KICYPLPESVDIQEENQ"
     gene            1722..2693
                     /locus_tag="L1V17_003123"
     CDS             1722..2693
                     /locus_tag="L1V17_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HBN1237787.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVSHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            2686..3714
                     /gene="vanB"
                     /locus_tag="L1V17_003124"
     CDS             2686..3714
                     /gene="vanB"
                     /locus_tag="L1V17_003124"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HBN1237788.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKAAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGIFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            3720..4328
                     /locus_tag="L1V17_003125"
     CDS             3720..4328
                     /locus_tag="L1V17_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HBN1237789.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(4394..4567)
                     /locus_tag="L1V17_003126"
     CDS             complement(4394..4567)
                     /locus_tag="L1V17_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBN1237790.1"
                     /translation="MLPEKNGGLDFSKPPPAKYKMGVGKVCPTAVFFFSAAGQIEYYN
                     LQCITKDALTTFQ"
BASE COUNT         1329 a          986 c         1245 g         1142 t
ORIGIN      
        1 gatagaatga ttttctatca gtcctagaaa ttatagagcc gattttgacc gacaggtata
       61 accctgccgg tctttttttg ctgctacagg aaaactacag actggctaca gggaaagtac
      121 agatgcgctt gccataataa caatcgtacc agccacaaat cgtagtttta ttgcaaagga
      181 ggcattcgat caaatggaaa aaagcaacta tcattccaat gcggatcatc acaaacggca
      241 tatgaaacaa tccgtggaaa agcgggcttt tctatgtgcg ttcattattt cgttcacagt
      301 ctgcacgctg tttttggggt ggagactggc ttccgtattg gaggcaacac agataccgcc
      361 catccctgca actcatacag gcagcagcac tgacgtagtg gagaatttgg aggaaaacgc
      421 tcttgccacc gccaaagaac agggagatga acaggaatgg agcctgattt tagtgaacag
      481 gcagaacccc atccccgcac agtacgatgt ggagcttgag caactatcaa atggtgagcg
      541 gatagatatt cggatttctc cctatcttca agatttgttt gatgccgcaa gaactgatgg
      601 agtttacccg attgtcgcat ccggataccg aacaacagaa aaacagcaag aaattatgga
      661 tgaaaaaatt gccgaatata aggcgaaagg ctacacctct gcacaggcta aagcggaagc
      721 agaaacttgg gtggccgtgc cgggaacgag cgagcatcag cttggtcttg ctgtggatat
      781 caatgcggac ggaattcatt caacaggcaa cgaggtttat agatggctgg atgaaaacag
      841 ctatcgtttt ggttttattc gtcgctaccc accagacaag acagagataa ccggtgtgag
      901 caacgagccg tggcattacc gatatgttgg catcgaagct gccacagaga tgtacaacca
      961 aggggtttgc cttgaggaat atttaaaacc agaaaaatga gaaaaggatg ttatgttatg
     1021 gacagaaaaa gattgacaca gcgtttcccg ttcctgcttc caatgagacg ggcgcagaga
     1081 aaaatgtgct tttatgcggg aatgagattt gacggctgtc gctatgcgca gacgataggg
     1141 gaaaaatcgc tttcccattt gctctttgaa acggattgcg cattatacaa ccacaatacc
     1201 ggatttgaca tgatatacca ggaaaacaag gtgttcaact taaagctggc agcaaagacc
     1261 ttaaacggct tattgataag accgggggaa accttttctt tctggttgtt cctgcatacg
     1321 ccattgacaa ttatccagcg cagaggtcac gaagtaaagg agtttccaga gccaaacagt
     1381 gacgagatta aaggggtgga tgcaaccatt tcagagggct ggattgattt aaaagtgcga
     1441 aacgataccg actgcaccta ccaaatatgg gtgaccttag atgatgagaa aatcatcggt
     1501 caggtgttcg ccgacaaaga gccccaagca ttatacaaaa ttacaaatgg cagtatccag
     1561 tatgtccgtg aaagtggcgg gatttatgaa tatgcccagg ttaaacggat gcaagttgcc
     1621 ttaggtaccg gggaaataat agattgcaag ctgctttata caaacaaatg caaaatctgt
     1681 tatcccctcc cggaaagtgt ggatattcag gaggagaacc aatgagaaaa agtgtgggca
     1741 ttactgtttt tggatgcgaa caggatgagg caaatgcttt ccgcgcttta tcgccggatt
     1801 ttcatattat ccctacgctg attagcgatg cgatatcggc agacaacgca aaattggccg
     1861 ctggcaatca atgcgttagc gtaagccata agtccgaggt ttccgaggcg acaattcttg
     1921 cgctgagaaa ggtcggggta aaatacattt ctacccgcag catcggctgc gatcacattg
     1981 atacgactgc cgccgagaga atgggaatct cggttggcac ggttgcgtat tcgccggaca
     2041 gcgttgcgga ttatgctttg atgctgatgc tgatggccat acggggtgca aaacccacca
     2101 tgcacgccgt ggcgcaacaa gatttcagat tggatcgtat ccgggggaaa gaactggggg
     2161 atatgactgt gggagttatt ggaaccggcc atatcgggca agcggtcgtc aaaaggctgc
     2221 ggggatttgg atgccatgtg ctggcctatg ataacagccg aaaaatggat gcagattatg
     2281 tccagcttga tgagcttcta aaaaacagcg atattgttac gctccatgtg ccgctttgtg
     2341 cggatacccg ccatctgatc ggtcagaagc aaattggaga gatgaagcaa ggcgcatttt
     2401 taatcaacac cgggcgcgga gcgcttgtcg ataccggggc gctggtggag gcgttggaaa
     2461 gcggaaagct gggtggtgcg gcactggatg tgttggaggg cgaggatcag tttgtttata
     2521 ccgattgctc gcagaaagtg cttgaccatc cctttttgtc gcagctttta aggatgccga
     2581 atgtgatcat cacaccccat acggcgtact acactgagcg tgtgctgcag gatactacag
     2641 aaaaaacaat caggaattgt ctcaattttg aaaggagttt acagcatgaa tagaataaaa
     2701 gtcgcaatca tcttcggcgg ttgctcggag gaacatgatg tgtcggtaaa agccgcaata
     2761 gaaattgctg cgaacattga tacggaaaaa ttcgatccgc actacatcgg aattacaaaa
     2821 aacggtgtat ggaagctatg caagaagcca tgtacggaat gggaagccga cagtctcccc
     2881 gccatactct ccccggatag gaaaacgcat gggctgcttg tcatgaaaga aagcgaatac
     2941 gaaacacggc gtattgatgt ggctttcccg gttttgcatg gcaaatgcgg ggaggatggt
     3001 gcgatacagg ggctgtttgt attgtctggt atcccctatg tgggctgtga tattcaaagc
     3061 tccgcagctt gcatggacaa atcactggcc tacattctta caaaaaatgc gggcatcgcc
     3121 gttcccgaat ttcaaatgat tgataaaggt gacaagccgg aggcgggtgc gcttacctac
     3181 cctgtctttg tgaagccggc acggtcaggt tcgtcctttg gcgtaaccaa agtaaacggt
     3241 acggaagaac ttaacgctgc gatagaagcg gcaggacaat atgatggaaa aatcttaatt
     3301 gagcaagcga tttcgggctg tgaggtcggg tgtgcggtca tggggaacga ggatgatttg
     3361 attgtcggcg aagtggatca aatccggctg agccacggta tcttccgcat ccatcaggaa
     3421 aacgagccgg aaaaaggctc agaaaatgcg atgattacag ttcccgcaga cattccggtc
     3481 gaggaacgaa atcgggtgca ggaaacggca aagaaagtat atcgggtgct tggatgcaga
     3541 gggcttgccc gtgttgatct ttttttgcag gaggatggcg gcatcgttct aaatgaggtc
     3601 aataccctgc ccggttttac atcgtacagc cgctacccac gtatgatggc cgccgcagga
     3661 atcacgcttc ctgcactgat tgacagcctg attacattgg cgttaaagag gtgataagta
     3721 tggaaaatgg ttttttgttt ttagatgaaa tgttgcatgg cgtccgttgg gatgccaagt
     3781 acgccacatg ggataacttc acaggaaaac cggtggatgg gtatgaggtg aatcgcatca
     3841 tcggcacaaa ggccgtggcg tttgctctgc gcgaggcaca aatccatgcg gctgcgcttg
     3901 gctatggctt gcttttatgg gatggatatc ggccaagaac tgcggtggac tgcttcctgc
     3961 gttgggcagc gcaaccggag gacaatctca caaaagaaaa attttacccc aatatagagc
     4021 gagccgagtt gattacaaag ggttatgtgg cctcacaatc cagccatagc cgtggaagcg
     4081 caattgatct tacgctctac cacctggata caggggaact tgtttcaatg ggaagtaact
     4141 tcgattttat ggacgaacgg tcgcatcata cagcaaaagg gataggggat gcagaggcac
     4201 aaaatcgaag atgcttgcgt aaaatcatgg aaagcagcgg atttcagtct tatcgctttg
     4261 aatggtggca ctataagttg attgatgagc cataccccga tacctatttt aattttgccg
     4321 tttcataatg aaagtattgg ttttgtatca gattttggat ttgataaaat ctatgctggt
     4381 catggacaat cttttactgg aaagtggtta aagcatcttt tgtaatacat tgcaaattat
     4441 agtattcaat ctgcccagcg gcagaaaaga aaaaaaccgc tgttgggcag acctttccca
     4501 cgcccatttt gtattttgct ggcggcggtt ttgagaaatc aaggccgccg ttcttttctg
     4561 gcagcaaaag gtgtggcggc ccataggagg atgccgctat gctgttttgc tattgccatg
     4621 ctctaatcca cttccaccac tcaaaaaaag ccttgcccct ccatgaactg aaccccaaaa
     4681 gttgaactat ttaatggact gt
//
LOCUS       DAFLWC010000275         2704 bp    DNA     linear   BCT 15-JAN-2022
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE-ING-27
            SAMN14852342-rid13729623.guided.175, whole genome shotgun sequence.
ACCESSION   DAFLWC010000275 DAFLWC010000000
VERSION     DAFLWC010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14852342
            Sequence Read Archive: SRR11730528
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-JAN-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001222339.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001222339.1
            Genome Coverage       :: 157x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/14/2022 05:38:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,131
            CDSs (total)                      :: 3,068
            Genes (coding)                    :: 2,995
            CDSs (with protein)               :: 2,995
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 31 of 73
            Pseudo Genes (incomplete)         :: 32 of 73
            Pseudo Genes (internal stop)      :: 17 of 73
            Pseudo Genes (multiple problems)  :: 6 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2704
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14852342-rid13729623.guided.175"
                     /isolate="VRE-ING-27"
                     /isolation_source="screening"
                     /host="Homo sapiens sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Hesse"
                     /collection_date="2017"
     gene            43..126
                     /locus_tag="L1V17_003127"
     CDS             43..126
                     /locus_tag="L1V17_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBN1237791.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            251..988
                     /gene="erm(B)"
                     /locus_tag="L1V17_003128"
     CDS             251..988
                     /gene="erm(B)"
                     /locus_tag="L1V17_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBN1237792.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1251..2114)
                     /locus_tag="L1V17_003129"
     CDS             complement(1251..2114)
                     /locus_tag="L1V17_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBN1237793.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(2116..2388)
                     /locus_tag="L1V17_003130"
     CDS             complement(2116..2388)
                     /locus_tag="L1V17_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBN1237794.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            complement(2405..2614)
                     /locus_tag="L1V17_003131"
     CDS             complement(2405..2614)
                     /locus_tag="L1V17_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HBN1237795.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
BASE COUNT          823 a          482 c          433 g          966 t
ORIGIN      
        1 attagatgct aaaaatttgt aattaagaag gagggattcg tcatgttggt attccaaatg
       61 cgtaatgtag ataaaacatc taccgttttg aaacagacta aaaacagtga ttacgcagat
      121 aaataaatac gttagattaa ttcctaccag tgactaatct tatgactttt taaacagata
      181 actaaaatta caaacaaatc gtttaacttc tgtatttatt tatagatgta atcacttcag
      241 gagtgattac atgaacaaaa atataaaata ttctcaaaac tttttaacga gtgaaaaagt
      301 actcaaccaa ataataaaac aattgaattt aaaagaaacc gataccgttt acgaaattgg
      361 aacaggtaaa gggcatttaa cgacgaaact ggctaaaata agtaaacagg taacgtctat
      421 tgaattagac agtcatctat tcaacttatc gtcagaaaaa ttaaaactga acactcgtgt
      481 cactttaatt caccaagata ttctacagtt tcaattccct aacaaacaga ggtataaaat
      541 tgttgggaat attccttacc atttaagcac acaaattatt aaaaaagtgg tttttgaaag
      601 ccatgcgtct gacatctatc tgattgttga agaaggattc tacaagcgta ccttggatat
      661 tcaccgaaca ctagggttgc tcttgcacac tcaagtctcg attcagcaat tgcttaagct
      721 gccagcggaa tgctttcatc ctaaaccaaa agtaaacagt gtcttaataa aacttacccg
      781 ccataccaca gatgttccag ataaatattg gaagctatat acgtactttg tttcaaaatg
      841 ggtcaatcga gaatatcgtc aactgtttac taaaaatcag tttcatcaag caatgaaaca
      901 cgccaaagta aacaatttaa gtaccgttac ttatgagcaa gtattgtcta tttttaatag
      961 ttatctatta tttaacggga ggaaataatt ctatgagtcg cttttgtaaa tttggaaagt
     1021 tacacgttac taaagggaat gtagataaat tattaggtat agggcacctc taataactac
     1081 caattaattc acctcaaaat gaaattagaa aaaaacagcg aaatttttaa atctatttct
     1141 tatcgataca aattcctcgt aggcgctcgg gaccccaaca tgaggaaatg tttttataaa
     1201 aaaagagtag ttaccgtttt ttggtaacta ctcttttcct tttttaaggt ttaaatacct
     1261 ggaagtttag gtgttttggg tattggtggt gtaggtagct gcaagctttc cattttttgt
     1321 tgaattgctt taaattcagg ggtttcttgg tgttgatttt gaaccatttt ttgctctatt
     1381 ctctccaaag tcggttgaat ttctttccct gatactttac gatttaattc tctttctaag
     1441 gtctctttcg gactaatgga aggcgtttct aagcttgaat agagtttcac tccttctcta
     1501 ttgtaaagcc ttatatcgct aaataagccc gttttatgaa gggtttctaa attggtcggt
     1561 aagtttttga caacaatatc atgcgcttgt tttggtgttg ccctagctgt cattggatca
     1621 tctgcataca tggtttcata tcgttcaatc gttcctaagt atgattcaat tttcggtact
     1681 gccatgacgt atatttttgt ttcataacct ttagattgaa gcattgtggc tgtttgaatg
     1741 ggaacgtctg ttgttcgtcc tgttccttca atcactaaat tatagccttg atcgcttaaa
     1801 cggctaataa gtgcttctgt catgcgattc gaataagggg taacgtgttt tactacgtct
     1861 ttttcataga gtttcactaa ttcgtcaaaa tttgggtgct gttgtttaaa ggtatcatta
     1921 tcaatgacaa taacattccc ttgtgtttct tcaaaaattg ctgatcgcaa actggttttc
     1981 cctgaccctg gttgcccacc aagtaaaaaa gcggttggcg attcaaccgc tagtctattt
     2041 ttagttagtc gttcaacatt cttttctaaa cgatcttcaa attgcttttc ggtgaagtca
     2101 gtaatattcg ccatgttaag ccactttctc tttattcaaa atttgttttg aatattgatt
     2161 cattgaccgc caatactcat gaatagcttg taattcttca aatggttgtt gaaataaatc
     2221 aacttcttgt gccacttcta attgatttaa aagattcact tctagtaaac gagtattttt
     2281 agtatctagt tcatgattca aaacataatt taatacccga ttataaacac ttgccgataa
     2341 ctcattaatg atttcaattt caaatgtttt ttcatacgta actgccattt cattttcact
     2401 ccttttaaag tttgtcaggt aaatatttcc gtatatattc ttctaaggct tgatccataa
     2461 cttcttttac gtttccgcca ttctttgctg tttcgatttt tatgatatgg tgcaagtcgg
     2521 cacgaacacg aaccgtctta tcccccatta tatctttttt tgcgctgatt ggcgtatcat
     2581 ttcgttttgc tttctgtgcg cctaaatttc ccacgatcgc tcacttcttt ctatttcttc
     2641 ttactattta ttttatcatc acctatcaca aatcacaagt gatttgtgat taatcacttg
     2701 tgat
//
